ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0038024 cargo receptor activity 18/862 65/18639 0.276923076923077 5.98789933963948 5.01973764712248e-10 5.34100085653832e-07 GO:0015399 primary active transmembrane transporter activity 25/862 166/18639 0.150602409638554 3.25647136108238 1.84382700612968e-07 9.80915967260992e-05 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 14/862 59/18639 0.23728813559322 5.13087419874946 3.51147342686356e-07 0.000119436617276169 GO:0022853 active monoatomic ion transmembrane transporter activity 20/862 118/18639 0.169491525423729 3.6649101419639 4.49009839384094e-07 0.000119436617276169 GO:0009055 electron transfer activity 19/862 116/18639 0.163793103448276 3.54169333546684 1.48358157956389e-06 0.000264976748907526 GO:0004601 peroxidase activity 13/862 57/18639 0.228070175438596 4.93155452436195 1.49422978707251e-06 0.000264976748907526 GO:0016209 antioxidant activity 16/862 86/18639 0.186046511627907 4.02287810931851 1.76178311812889e-06 0.000267791033955592 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 14/862 68/18639 0.205882352941176 4.4517879077385 2.20889050167971e-06 0.000293782436723402 GO:0015078 proton transmembrane transporter activity 24/862 185/18639 0.12972972972973 2.80514203298426 4.90475989233928e-06 0.000579851613938777 GO:0005044 scavenger receptor activity 8/862 27/18639 0.296296296296296 6.40680587780356 2.05065241705992e-05 0.00218189417175175 GO:0038187 pattern recognition receptor activity 10/862 48/18639 0.208333333333333 4.50478538283063 5.60342475039841e-05 0.00542003994038538 GO:0001851 complement component C3b binding 5/862 11/18639 0.454545454545455 9.82862265344864 7.65077615834122e-05 0.00678368819372922 GO:0035615 clathrin adaptor activity 6/862 18/18639 0.333333333333333 7.207656612529 0.000110551713784507 0.00904823257436269 GO:0003725 double-stranded RNA binding 12/862 75/18639 0.16 3.45967517401392 0.000157713508255612 0.0113144060610607 GO:0051287 NAD binding 10/862 54/18639 0.185185185185185 4.00425367362722 0.000159507604244277 0.0113144060610607 GO:0017154 semaphorin receptor activity 5/862 13/18639 0.384615384615385 8.31652686061039 0.000197219358220081 0.0131150873216354 GO:0043394 proteoglycan binding 8/862 37/18639 0.216216216216216 4.67523672164043 0.000236500272107627 0.014802134677795 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 6/862 21/18639 0.285714285714286 6.17799138216772 0.000286849041632643 0.0156577173667181 GO:0140312 cargo adaptor activity 6/862 21/18639 0.285714285714286 6.17799138216772 0.000286849041632643 0.0156577173667181 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 10/862 58/18639 0.172413793103448 3.72809824785983 0.000294317995615001 0.0156577173667181 GO:0022804 active transmembrane transporter activity 38/862 457/18639 0.0831509846827133 1.79797123375997 0.000361687739466692 0.0183255121329791 GO:0004129 cytochrome-c oxidase activity 5/862 15/18639 0.333333333333333 7.207656612529 0.000425906256805679 0.0205983753291474 GO:0005543 phospholipid binding 40/862 497/18639 0.0804828973843058 1.74027926258246 0.000493281679386819 0.0220324657670251 GO:0008137 NADH dehydrogenase (ubiquinone) activity 8/862 41/18639 0.195121951219512 4.21911606587064 0.00049697291203816 0.0220324657670251 GO:0016675 oxidoreductase activity, acting on a heme group of donors 5/862 16/18639 0.3125 6.75717807424594 0.000596026629500681 0.025366893351549 GO:0004622 lysophospholipase activity 6/862 24/18639 0.25 5.40574245939675 0.000631780661206061 0.025854408597048 GO:0008190 eukaryotic initiation factor 4E binding 4/862 10/18639 0.4 8.6491879350348 0.000762549604288339 0.0289768849629569 GO:0031720 haptoglobin binding 4/862 10/18639 0.4 8.6491879350348 0.000762549604288339 0.0289768849629569 GO:0003954 NADH dehydrogenase activity 8/862 44/18639 0.181818181818182 3.93144906137946 0.000815623195270815 0.0299249337851085 GO:0033218 amide binding 23/862 247/18639 0.0931174089068826 2.01347492414778 0.00116556468290961 0.0413386940871941 GO:0005178 integrin binding 17/862 161/18639 0.105590062111801 2.28317072819242 0.0012918391603735 0.0431509330806343 GO:0042277 peptide binding 23/862 249/18639 0.0923694779116466 1.99730243479719 0.00129777242347772 0.0431509330806343 GO:0050145 nucleoside monophosphate kinase activity 5/862 19/18639 0.263157894736842 5.69025522041763 0.00141346519137218 0.0455735443521211 GO:0001540 amyloid-beta binding 11/862 83/18639 0.132530120481928 2.8656947977525 0.00149427296707604 0.0459061738385793 GO:0097718 disordered domain specific binding 6/862 28/18639 0.214285714285714 4.63349353662579 0.001510071507848 0.0459061738385793 GO:0016801 hydrolase activity, acting on ether bonds 4/862 12/18639 0.333333333333333 7.207656612529 0.00166877870088943 0.046725803624904 GO:0016803 ether hydrolase activity 4/862 12/18639 0.333333333333333 7.207656612529 0.00166877870088943 0.046725803624904 GO:0097677 STAT family protein binding 4/862 12/18639 0.333333333333333 7.207656612529 0.00166877870088943 0.046725803624904 GO:0051015 actin filament binding 20/862 209/18639 0.0956937799043062 2.0691837165155 0.00171574265110742 0.0468089789943153 GO:0016776 phosphotransferase activity, phosphate group as acceptor 7/862 39/18639 0.179487179487179 3.88104586828485 0.00185757830182866 0.0494115828286423 GO:0048029 monosaccharide binding 10/862 74/18639 0.135135135135135 2.92202295102527 0.0020845495947839 0.0540966041182945 GO:0001846 opsonin binding 5/862 21/18639 0.238095238095238 5.14832615180643 0.00229065455520885 0.0580299153986241 GO:0016651 oxidoreductase activity, acting on NAD(P)H 11/862 88/18639 0.125 2.70287122969838 0.00240528840029016 0.0595169036722961 GO:0001530 lipopolysaccharide binding 7/862 41/18639 0.170731707317073 3.69172655763681 0.00250627389930491 0.0606062597468279 GO:0008238 exopeptidase activity 12/862 102/18639 0.117647058823529 2.543878804422 0.00261684306438423 0.0618738004556627 GO:0005344 oxygen carrier activity 4/862 14/18639 0.285714285714286 6.17799138216772 0.00313387362524302 0.0695831478442675 GO:0005347 ATP transmembrane transporter activity 4/862 14/18639 0.285714285714286 6.17799138216772 0.00313387362524302 0.0695831478442675 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 11/862 91/18639 0.120879120879121 2.61376558476326 0.00313908937643312 0.0695831478442675 GO:0019205 nucleobase-containing compound kinase activity 7/862 44/18639 0.159090909090909 3.44001792870702 0.0037894947187789 0.0814738772914642 GO:0005096 GTPase activator activity 23/862 271/18639 0.0848708487084871 1.83515980171403 0.00382865964715527 0.0814738772914642 GO:0004559 alpha-mannosidase activity 4/862 15/18639 0.266666666666667 5.7661252900232 0.00411858903194751 0.0859250731371011 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 13/862 122/18639 0.10655737704918 2.30408694990681 0.00424373913325372 0.0863830572975503 GO:0004175 endopeptidase activity 31/862 405/18639 0.0765432098765432 1.65509151843259 0.00430291544809226 0.0863830572975503 GO:0004620 phospholipase activity 12/862 109/18639 0.110091743119266 2.38051044083527 0.00452922122775742 0.0892424330802574 GO:0097110 scaffold protein binding 9/862 70/18639 0.128571428571429 2.78009612197547 0.00480893835580666 0.0928611624014288 GO:0030276 clathrin binding 7/862 46/18639 0.152173913043478 3.29045193180672 0.0048874296000752 0.0928611624014288 GO:0001848 complement binding 5/862 25/18639 0.2 4.3245939675174 0.00513201110763599 0.0957975406758718 GO:0015923 mannosidase activity 4/862 16/18639 0.25 5.40574245939675 0.00529277649942979 0.0970950723343672 GO:0001786 phosphatidylserine binding 8/862 59/18639 0.135593220338983 2.93192811357112 0.00555393117009754 0.0985518700429054 GO:0042626 ATPase-coupled transmembrane transporter activity 11/862 98/18639 0.112244897959184 2.42706804299446 0.00555743628061496 0.0985518700429054 GO:0070006 metalloaminopeptidase activity 5/862 26/18639 0.192307692307692 4.15826343030519 0.00611616656515679 0.10668198730044 GO:0004550 nucleoside diphosphate kinase activity 4/862 17/18639 0.235294117647059 5.087757608844 0.00667134909063076 0.110911178631736 GO:0030169 low-density lipoprotein particle binding 4/862 17/18639 0.235294117647059 5.087757608844 0.00667134909063076 0.110911178631736 GO:0048038 quinone binding 4/862 17/18639 0.235294117647059 5.087757608844 0.00667134909063076 0.110911178631736 GO:0015026 coreceptor activity 8/862 61/18639 0.131147540983607 2.83579932296223 0.00680439166986597 0.111382657488268 GO:0030695 GTPase regulator activity 35/862 489/18639 0.0715746421267894 1.54765632784365 0.00717437771799421 0.11241402571288 GO:0023026 MHC class II protein complex binding 5/862 27/18639 0.185185185185185 4.00425367362722 0.00722570699363838 0.11241402571288 GO:0016798 hydrolase activity, acting on glycosyl bonds 13/862 130/18639 0.1 2.1622969837587 0.00722691361866225 0.11241402571288 GO:0004197 cysteine-type endopeptidase activity 10/862 88/18639 0.113636363636364 2.45715566336216 0.00735387059721609 0.11241402571288 GO:0060589 nucleoside-triphosphatase regulator activity 35/862 490/18639 0.0714285714285714 1.54449784554193 0.00739565958637369 0.11241402571288 GO:0044389 ubiquitin-like protein ligase binding 25/862 322/18639 0.077639751552795 1.67880200602384 0.0081668046771681 0.117298228502326 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 13/862 132/18639 0.0984848484848485 2.12953490824721 0.0081850180198805 0.117298228502326 GO:0030228 lipoprotein particle receptor activity 4/862 18/18639 0.222222222222222 4.80510440835267 0.00826820219706246 0.117298228502326 GO:0034185 apolipoprotein binding 4/862 18/18639 0.222222222222222 4.80510440835267 0.00826820219706246 0.117298228502326 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 4/862 18/18639 0.222222222222222 4.80510440835267 0.00826820219706246 0.117298228502326 GO:0003743 translation initiation factor activity 7/862 51/18639 0.137254901960784 2.967858605159 0.00866662330813412 0.121332726313878 GO:0072341 modified amino acid binding 10/862 91/18639 0.10989010989011 2.37615053160297 0.00925827221527525 0.126440294660704 GO:0016853 isomerase activity 16/862 180/18639 0.0888888888888889 1.92204176334107 0.00948111550679337 0.126440294660704 GO:0004177 aminopeptidase activity 6/862 40/18639 0.15 3.24344547563805 0.00961697574337599 0.126440294660704 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 6/862 40/18639 0.15 3.24344547563805 0.00961697574337599 0.126440294660704 GO:0005080 protein kinase C binding 7/862 52/18639 0.134615384615385 2.91078440121364 0.00962562393563632 0.126440294660704 GO:0005346 purine ribonucleotide transmembrane transporter activity 4/862 19/18639 0.210526315789474 4.55220417633411 0.0100961320652466 0.129425114667739 GO:0008301 DNA binding, bending 4/862 19/18639 0.210526315789474 4.55220417633411 0.0100961320652466 0.129425114667739 GO:0019838 growth factor binding 13/862 136/18639 0.0955882352941176 2.06690152859288 0.0103994171998573 0.131725951198192 GO:0008235 metalloexopeptidase activity 8/862 66/18639 0.121212121212121 2.62096604091964 0.01085454152758 0.13460557548904 GO:0046906 tetrapyrrole binding 14/862 152/18639 0.0921052631578947 1.99158932714617 0.0109522916490548 0.13460557548904 GO:0030246 carbohydrate binding 22/862 280/18639 0.0785714285714286 1.69894763009612 0.0110329784623761 0.13460557548904 GO:0031210 phosphatidylcholine binding 5/862 30/18639 0.166666666666667 3.6038283062645 0.0113813555100193 0.13460557548904 GO:0070566 adenylyltransferase activity 5/862 30/18639 0.166666666666667 3.6038283062645 0.0113813555100193 0.13460557548904 GO:0019001 guanyl nucleotide binding 29/862 400/18639 0.0725 1.56766531322506 0.0115123189562994 0.13460557548904 GO:0032561 guanyl ribonucleotide binding 29/862 400/18639 0.0725 1.56766531322506 0.0115123189562994 0.13460557548904 GO:0008526 phosphatidylinositol transfer activity 3/862 11/18639 0.272727272727273 5.89717359206918 0.0123054631696135 0.136682974555447 GO:0015217 ADP transmembrane transporter activity 3/862 11/18639 0.272727272727273 5.89717359206918 0.0123054631696135 0.136682974555447 GO:0019864 IgG binding 3/862 11/18639 0.272727272727273 5.89717359206918 0.0123054631696135 0.136682974555447 GO:0032050 clathrin heavy chain binding 3/862 11/18639 0.272727272727273 5.89717359206918 0.0123054631696135 0.136682974555447 GO:0001618 virus receptor activity 9/862 81/18639 0.111111111111111 2.40255220417633 0.0123322984561305 0.136682974555447 GO:0070325 lipoprotein particle receptor binding 5/862 31/18639 0.161290322580645 3.48757578025597 0.0130657178302279 0.143318801766624 GO:0140272 exogenous protein binding 9/862 82/18639 0.109756097560976 2.37325278705223 0.0133027178894274 0.144429508513783 GO:0008200 ion channel inhibitor activity 6/862 43/18639 0.13953488372093 3.01715858198888 0.0135944906243979 0.146106444690499 GO:0005200 structural constituent of cytoskeleton 11/862 112/18639 0.0982142857142857 2.12368453762015 0.0145993385120904 0.153445498442889 GO:0031369 translation initiation factor binding 5/862 32/18639 0.15625 3.37858903712297 0.0149105487709756 0.153445498442889 GO:0071813 lipoprotein particle binding 5/862 32/18639 0.15625 3.37858903712297 0.0149105487709756 0.153445498442889 GO:0071814 protein-lipid complex binding 5/862 32/18639 0.15625 3.37858903712297 0.0149105487709756 0.153445498442889 GO:0016248 channel inhibitor activity 6/862 44/18639 0.136363636363636 2.94858679603459 0.0151426478726535 0.153445498442889 GO:0030547 signaling receptor inhibitor activity 6/862 44/18639 0.136363636363636 2.94858679603459 0.0151426478726535 0.153445498442889 GO:0019902 phosphatase binding 16/862 190/18639 0.0842105263157895 1.82088167053364 0.0153181748150526 0.153759792483169 GO:0042605 peptide antigen binding 6/862 45/18639 0.133333333333333 2.8830626450116 0.016808882251594 0.165598617737926 GO:0141110 transporter inhibitor activity 6/862 45/18639 0.133333333333333 2.8830626450116 0.016808882251594 0.165598617737926 GO:0005525 GTP binding 27/862 378/18639 0.0714285714285714 1.54449784554193 0.0171557274202129 0.167465082340427 GO:0016298 lipase activity 12/862 130/18639 0.0923076923076923 1.99596644654649 0.0174022891248814 0.168327596626126 GO:0045309 protein phosphorylated amino acid binding 7/862 59/18639 0.11864406779661 2.56543709937473 0.0186179913252621 0.17846434927999 GO:0008035 high-density lipoprotein particle binding 3/862 13/18639 0.230769230769231 4.98991611636623 0.0199094905343219 0.186043270735053 GO:0035325 Toll-like receptor binding 3/862 13/18639 0.230769230769231 4.98991611636623 0.0199094905343219 0.186043270735053 GO:0000295 adenine nucleotide transmembrane transporter activity 4/862 23/18639 0.173913043478261 3.76051649349339 0.0199332075787557 0.186043270735053 GO:0002020 protease binding 12/862 136/18639 0.0882352941176471 1.9079091033165 0.023904789017609 0.210879141369816 GO:0061135 endopeptidase regulator activity 15/862 184/18639 0.0815217391304348 1.76274210632503 0.02398787870847 0.210879141369816 GO:0004033 aldo-keto reductase (NADPH) activity 5/862 36/18639 0.138888888888889 3.00319025522042 0.0240076841785287 0.210879141369816 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 5/862 36/18639 0.138888888888889 3.00319025522042 0.0240076841785287 0.210879141369816 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 5/862 36/18639 0.138888888888889 3.00319025522042 0.0240076841785287 0.210879141369816 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 5/862 36/18639 0.138888888888889 3.00319025522042 0.0240076841785287 0.210879141369816 GO:0003779 actin binding 30/862 443/18639 0.0677200902934537 1.46430946981402 0.0241340176962989 0.210879141369816 GO:0031625 ubiquitin protein ligase binding 22/862 302/18639 0.0728476821192053 1.5751832332017 0.024179751172103 0.210879141369816 GO:0019763 immunoglobulin receptor activity 3/862 14/18639 0.214285714285714 4.63349353662579 0.0244846587822525 0.21180225157981 GO:0043178 alcohol binding 9/862 92/18639 0.0978260869565217 2.11529052759003 0.0263409965988142 0.221872553553483 GO:0015662 P-type ion transporter activity 4/862 25/18639 0.16 3.45967517401392 0.0264829081779063 0.221872553553483 GO:0120020 cholesterol transfer activity 4/862 25/18639 0.16 3.45967517401392 0.0264829081779063 0.221872553553483 GO:0140358 P-type transmembrane transporter activity 4/862 25/18639 0.16 3.45967517401392 0.0264829081779063 0.221872553553483 GO:0023023 MHC protein complex binding 5/862 37/18639 0.135135135135135 2.92202295102527 0.0267359062990471 0.222242221110829 GO:0051219 phosphoprotein binding 9/862 93/18639 0.0967741935483871 2.09254546815358 0.0280143375713273 0.231063993611568 GO:0005021 vascular endothelial growth factor receptor activity 6/862 51/18639 0.117647058823529 2.543878804422 0.0294912771212309 0.240221767159525 GO:0005041 low-density lipoprotein particle receptor activity 3/862 15/18639 0.2 4.3245939675174 0.0295761762198287 0.240221767159525 GO:0015216 purine nucleotide transmembrane transporter activity 4/862 26/18639 0.153846153846154 3.32661074424416 0.0301859521074972 0.241487616859978 GO:0050750 low-density lipoprotein particle receptor binding 4/862 26/18639 0.153846153846154 3.32661074424416 0.0301859521074972 0.241487616859978 GO:1901681 sulfur compound binding 20/862 275/18639 0.0727272727272727 1.57257962455178 0.0310011606752567 0.245800487356179 GO:0005516 calmodulin binding 16/862 207/18639 0.0772946859903382 1.67134066377484 0.0311870919107934 0.245800487356179 GO:0020037 heme binding 12/862 142/18639 0.0845070422535211 1.82729322571158 0.0320368979948785 0.250641613724637 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 5/862 39/18639 0.128205128205128 2.77217562020346 0.0327649238643581 0.254466270012241 GO:0061134 peptidase regulator activity 17/862 226/18639 0.0752212389380531 1.62650658070345 0.0337381050603551 0.260125679595781 GO:0015252 proton channel activity 4/862 27/18639 0.148148148148148 3.20340293890178 0.0341790382142552 0.261629472373868 GO:1901505 carbohydrate derivative transmembrane transporter activity 6/862 53/18639 0.113207547169811 2.44788337784004 0.0348172499895348 0.261759161581595 GO:0019955 cytokine binding 12/862 144/18639 0.0833333333333333 1.80191415313225 0.0351422038514411 0.261759161581595 GO:0000062 fatty-acyl-CoA binding 3/862 16/18639 0.1875 4.05430684454756 0.035180037693767 0.261759161581595 GO:0005324 long-chain fatty acid transmembrane transporter activity 3/862 16/18639 0.1875 4.05430684454756 0.035180037693767 0.261759161581595 GO:0050997 quaternary ammonium group binding 5/862 40/18639 0.125 2.70287122969838 0.036071773595927 0.266197122294227 GO:0051020 GTPase binding 22/862 315/18639 0.0698412698412698 1.51017567119655 0.0362768634705478 0.266197122294227 GO:0032934 sterol binding 7/862 68/18639 0.102941176470588 2.22589395386925 0.0371863465803073 0.266799402989574 GO:0045296 cadherin binding 23/862 334/18639 0.0688622754491018 1.48900690498354 0.0376424984159149 0.266799402989574 GO:0015485 cholesterol binding 6/862 54/18639 0.111111111111111 2.40255220417633 0.0376978510721376 0.266799402989574 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 6/862 54/18639 0.111111111111111 2.40255220417633 0.0376978510721376 0.266799402989574 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 6/862 54/18639 0.111111111111111 2.40255220417633 0.0376978510721376 0.266799402989574 GO:0008135 translation factor activity, RNA binding 8/862 83/18639 0.0963855421686747 2.08414167109272 0.0378634491084827 0.266799402989574 GO:0042169 SH2 domain binding 5/862 41/18639 0.121951219512195 2.63694754116915 0.0395767486505892 0.26951865710235 GO:0180051 translation factor activity 8/862 84/18639 0.0952380952380952 2.05933046072257 0.0402267849737369 0.26951865710235 GO:0017124 SH3 domain binding 10/862 115/18639 0.0869565217391304 1.8802582467467 0.0404401380939934 0.26951865710235 GO:0140313 molecular sequestering activity 6/862 55/18639 0.109090909090909 2.35886943682767 0.040726176017147 0.26951865710235 GO:0035091 phosphatidylinositol binding 20/862 284/18639 0.0704225352112676 1.52274435475965 0.041244365341777 0.26951865710235 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 3/862 17/18639 0.176470588235294 3.815818206633 0.041289042394439 0.26951865710235 GO:0008429 phosphatidylethanolamine binding 3/862 17/18639 0.176470588235294 3.815818206633 0.041289042394439 0.26951865710235 GO:0016805 dipeptidase activity 3/862 17/18639 0.176470588235294 3.815818206633 0.041289042394439 0.26951865710235 GO:0019198 transmembrane receptor protein phosphatase activity 3/862 17/18639 0.176470588235294 3.815818206633 0.041289042394439 0.26951865710235 GO:0038191 neuropilin binding 3/862 17/18639 0.176470588235294 3.815818206633 0.041289042394439 0.26951865710235 GO:0070403 NAD+ binding 3/862 17/18639 0.176470588235294 3.815818206633 0.041289042394439 0.26951865710235 GO:1901567 fatty acid derivative binding 3/862 17/18639 0.176470588235294 3.815818206633 0.041289042394439 0.26951865710235 GO:0051861 glycolipid binding 4/862 29/18639 0.137931034482759 2.98247859828786 0.0430422630016983 0.279101189011539 GO:0016859 cis-trans isomerase activity 5/862 42/18639 0.119047619047619 2.57416307590321 0.0432816693485939 0.279101189011539 GO:0008237 metallopeptidase activity 14/862 184/18639 0.0760869565217391 1.64522596590336 0.0467656469708855 0.291312084827158 GO:0008525 phosphatidylcholine transporter activity 3/862 18/18639 0.166666666666667 3.6038283062645 0.0478932104339143 0.291312084827158 GO:0016854 racemase and epimerase activity 3/862 18/18639 0.166666666666667 3.6038283062645 0.0478932104339143 0.291312084827158 GO:0070064 proline-rich region binding 3/862 18/18639 0.166666666666667 3.6038283062645 0.0478932104339143 0.291312084827158 GO:0001965 G-protein alpha-subunit binding 4/862 30/18639 0.133333333333333 2.8830626450116 0.0479131718465721 0.291312084827158 GO:0001968 fibronectin binding 4/862 30/18639 0.133333333333333 2.8830626450116 0.0479131718465721 0.291312084827158 GO:0008106 alcohol dehydrogenase (NADP+) activity 4/862 30/18639 0.133333333333333 2.8830626450116 0.0479131718465721 0.291312084827158 GO:0015215 nucleotide transmembrane transporter activity 4/862 30/18639 0.133333333333333 2.8830626450116 0.0479131718465721 0.291312084827158 GO:0016769 transferase activity, transferring nitrogenous groups 4/862 30/18639 0.133333333333333 2.8830626450116 0.0479131718465721 0.291312084827158 GO:0048019 receptor antagonist activity 4/862 30/18639 0.133333333333333 2.8830626450116 0.0479131718465721 0.291312084827158 GO:0005518 collagen binding 7/862 72/18639 0.0972222222222222 2.10223317865429 0.0483610553698429 0.292364562008596 GO:0016779 nucleotidyltransferase activity 11/862 136/18639 0.0808823529411765 1.74891667804013 0.050799491197494 0.305370952735218 GO:0047499 calcium-independent phospholipase A2 activity 4/862 31/18639 0.129032258064516 2.79006062420477 0.0530757576267712 0.317261832106093 GO:0003727 single-stranded RNA binding 8/862 89/18639 0.0898876404494382 1.94363773821007 0.0535082664637778 0.318060310153405 GO:0015245 fatty acid transmembrane transporter activity 3/862 19/18639 0.157894736842105 3.41415313225058 0.0549801626280395 0.321422489210077 GO:0046624 sphingolipid transporter activity 3/862 19/18639 0.157894736842105 3.41415313225058 0.0549801626280395 0.321422489210077 GO:0120227 acyl-CoA binding 3/862 19/18639 0.157894736842105 3.41415313225058 0.0549801626280395 0.321422489210077 GO:0008201 heparin binding 13/862 172/18639 0.0755813953488372 1.63429423191065 0.0563075144851328 0.32738358148733 GO:0005539 glycosaminoglycan binding 17/862 242/18639 0.0702479338842975 1.51896895553297 0.0575489975283022 0.332783333533226 GO:0004714 transmembrane receptor protein tyrosine kinase activity 6/862 60/18639 0.1 2.1622969837587 0.0581332517395999 0.333014534015858 GO:0140375 immune receptor activity 12/862 156/18639 0.0769230769230769 1.66330537212208 0.058333882292597 0.333014534015858 GO:0120015 sterol transfer activity 4/862 32/18639 0.125 2.70287122969838 0.0585279303204563 0.333014534015858 GO:0000339 RNA cap binding 3/862 20/18639 0.15 3.24344547563805 0.0625354662246697 0.35019861085815 GO:0042288 MHC class I protein binding 3/862 20/18639 0.15 3.24344547563805 0.0625354662246697 0.35019861085815 GO:0043024 ribosomal small subunit binding 3/862 20/18639 0.15 3.24344547563805 0.0625354662246697 0.35019861085815 GO:0019239 deaminase activity 4/862 33/18639 0.121212121212121 2.62096604091964 0.0642667042347728 0.355595406745506 GO:0140311 protein sequestering activity 4/862 33/18639 0.121212121212121 2.62096604091964 0.0642667042347728 0.355595406745506 GO:0001784 phosphotyrosine residue binding 5/862 47/18639 0.106382978723404 2.30031594016883 0.0648360046133723 0.355595406745506 GO:0140359 ABC-type transporter activity 5/862 47/18639 0.106382978723404 2.30031594016883 0.0648360046133723 0.355595406745506 GO:0031267 small GTPase binding 19/862 283/18639 0.0671378091872792 1.45171882301821 0.067135229293053 0.366317353681068 GO:0005319 lipid transporter activity 13/862 178/18639 0.0730337078651685 1.57920566229568 0.069883121059529 0.370137071512871 GO:0015035 protein-disulfide reductase activity 4/862 34/18639 0.117647058823529 2.543878804422 0.0702882529488661 0.370137071512871 GO:0019825 oxygen binding 4/862 34/18639 0.117647058823529 2.543878804422 0.0702882529488661 0.370137071512871 GO:0004866 endopeptidase inhibitor activity 12/862 161/18639 0.0745341614906832 1.61164992578288 0.070461457576814 0.370137071512871 GO:1902936 phosphatidylinositol bisphosphate binding 9/862 111/18639 0.0810810810810811 1.75321377061516 0.0717764544243255 0.370137071512871 GO:0046332 SMAD binding 7/862 79/18639 0.0886075949367089 1.91595935269758 0.0725907557317751 0.370137071512871 GO:0008083 growth factor activity 12/862 162/18639 0.0740740740740741 1.60170146945089 0.0730687688028422 0.370137071512871 GO:0004857 enzyme inhibitor activity 26/862 416/18639 0.0625 1.35143561484919 0.0742501253551098 0.370137071512871 GO:0060590 ATPase regulator activity 5/862 49/18639 0.102040816326531 2.20642549363133 0.0748686966339863 0.370137071512871 GO:0004090 carbonyl reductase (NADPH) activity 2/862 10/18639 0.2 4.3245939675174 0.075140608502613 0.370137071512871 GO:0005345 purine nucleobase transmembrane transporter activity 2/862 10/18639 0.2 4.3245939675174 0.075140608502613 0.370137071512871 GO:0005381 iron ion transmembrane transporter activity 2/862 10/18639 0.2 4.3245939675174 0.075140608502613 0.370137071512871 GO:0005528 FK506 binding 2/862 10/18639 0.2 4.3245939675174 0.075140608502613 0.370137071512871 GO:0008239 dipeptidyl-peptidase activity 2/862 10/18639 0.2 4.3245939675174 0.075140608502613 0.370137071512871 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/862 10/18639 0.2 4.3245939675174 0.075140608502613 0.370137071512871 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/862 10/18639 0.2 4.3245939675174 0.075140608502613 0.370137071512871 GO:0031419 cobalamin binding 2/862 10/18639 0.2 4.3245939675174 0.075140608502613 0.370137071512871 GO:0043422 protein kinase B binding 2/862 10/18639 0.2 4.3245939675174 0.075140608502613 0.370137071512871 GO:0047429 nucleoside triphosphate diphosphatase activity 2/862 10/18639 0.2 4.3245939675174 0.075140608502613 0.370137071512871 GO:0050815 phosphoserine residue binding 2/862 10/18639 0.2 4.3245939675174 0.075140608502613 0.370137071512871 GO:1905394 retromer complex binding 2/862 10/18639 0.2 4.3245939675174 0.075140608502613 0.370137071512871 GO:0004623 phospholipase A2 activity 4/862 35/18639 0.114285714285714 2.47119655286709 0.0765879650467003 0.375528086680595 GO:0061133 endopeptidase activator activity 3/862 22/18639 0.136363636363636 2.94858679603459 0.0789849850512102 0.383890779721342 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 10/862 130/18639 0.0769230769230769 1.66330537212208 0.0791460256158982 0.383890779721342 GO:0120013 lipid transfer activity 6/862 65/18639 0.0923076923076923 1.99596644654649 0.0793759131002774 0.383890779721342 GO:0004190 aspartic-type endopeptidase activity 4/862 36/18639 0.111111111111111 2.40255220417633 0.0831605001552217 0.400374534683963 GO:0003713 transcription coactivator activity 17/862 256/18639 0.06640625 1.43590034077726 0.0862822149805419 0.401671954662312 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/862 23/18639 0.130434782608696 2.82038737012004 0.0878427516720783 0.401671954662312 GO:0004602 glutathione peroxidase activity 3/862 23/18639 0.130434782608696 2.82038737012004 0.0878427516720783 0.401671954662312 GO:0031681 G-protein beta-subunit binding 3/862 23/18639 0.130434782608696 2.82038737012004 0.0878427516720783 0.401671954662312 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 3/862 23/18639 0.130434782608696 2.82038737012004 0.0878427516720783 0.401671954662312 GO:1901981 phosphatidylinositol phosphate binding 13/862 185/18639 0.0702702702702703 1.51945193453314 0.0882283712274766 0.401671954662312 GO:0008199 ferric iron binding 2/862 11/18639 0.181818181818182 3.93144906137946 0.0891039741321684 0.401671954662312 GO:0015205 nucleobase transmembrane transporter activity 2/862 11/18639 0.181818181818182 3.93144906137946 0.0891039741321684 0.401671954662312 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/862 11/18639 0.181818181818182 3.93144906137946 0.0891039741321684 0.401671954662312 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/862 11/18639 0.181818181818182 3.93144906137946 0.0891039741321684 0.401671954662312 GO:0019107 myristoyltransferase activity 2/862 11/18639 0.181818181818182 3.93144906137946 0.0891039741321684 0.401671954662312 GO:0032794 GTPase activating protein binding 2/862 11/18639 0.181818181818182 3.93144906137946 0.0891039741321684 0.401671954662312 GO:0034713 type I transforming growth factor beta receptor binding 2/862 11/18639 0.181818181818182 3.93144906137946 0.0891039741321684 0.401671954662312 GO:0042608 T cell receptor binding 2/862 11/18639 0.181818181818182 3.93144906137946 0.0891039741321684 0.401671954662312 GO:0048185 activin binding 2/862 11/18639 0.181818181818182 3.93144906137946 0.0891039741321684 0.401671954662312 GO:0003924 GTPase activity 21/862 331/18639 0.0634441087613293 1.37185005011881 0.0894701628336164 0.401671954662312 GO:0070001 aspartic-type peptidase activity 4/862 37/18639 0.108108108108108 2.33761836082022 0.0899998448650612 0.402352247632038 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 5/862 52/18639 0.0961538461538462 2.0791317151526 0.0913960325487079 0.406884429421863 GO:0030414 peptidase inhibitor activity 12/862 169/18639 0.0710059171597633 1.53535880503576 0.093044452012769 0.412497070589943 GO:0030145 manganese ion binding 6/862 68/18639 0.0882352941176471 1.9079091033165 0.0939510858743629 0.413176150067758 GO:0008234 cysteine-type peptidase activity 13/862 187/18639 0.0695187165775401 1.50320111170391 0.0939742747334561 0.413176150067758 GO:0005315 phosphate transmembrane transporter activity 3/862 24/18639 0.125 2.70287122969838 0.0970964641042804 0.418162333804839 GO:0044325 transmembrane transporter binding 10/862 136/18639 0.0735294117647059 1.58992425276375 0.099445050774145 0.418162333804839 GO:0000340 RNA 7-methylguanosine cap binding 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0003995 acyl-CoA dehydrogenase activity 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0004000 adenosine deaminase activity 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0004032 aldose reductase (NADPH) activity 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0004300 enoyl-CoA hydratase activity 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0004875 complement receptor activity 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0005078 MAP-kinase scaffold activity 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0005095 GTPase inhibitor activity 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0005527 macrolide binding 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0008179 adenylate cyclase binding 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0031543 peptidyl-proline dioxygenase activity 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0035497 cAMP response element binding 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0070008 serine-type exopeptidase activity 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:1990459 transferrin receptor binding 2/862 12/18639 0.166666666666667 3.6038283062645 0.103754564026764 0.418162333804839 GO:0005537 D-mannose binding 3/862 25/18639 0.12 2.59475638051044 0.106725585366968 0.428513293699825 GO:0008081 phosphoric diester hydrolase activity 7/862 87/18639 0.0804597701149425 1.73977918233459 0.107671389596367 0.430685558385469 GO:0015036 disulfide oxidoreductase activity 4/862 40/18639 0.1 2.1622969837587 0.112049665252875 0.444853894884547 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 4/862 40/18639 0.1 2.1622969837587 0.112049665252875 0.444853894884547 GO:0003735 structural constituent of ribosome 12/862 175/18639 0.0685714285714286 1.48271793172025 0.112579351155838 0.445295277434246 GO:0004713 protein tyrosine kinase activity 10/862 140/18639 0.0714285714285714 1.54449784554193 0.114520555857745 0.447569080581744 GO:0004435 phosphatidylinositol phospholipase C activity 3/862 26/18639 0.115384615384615 2.49495805818312 0.116709015792116 0.447569080581744 GO:0008198 ferrous iron binding 3/862 26/18639 0.115384615384615 2.49495805818312 0.116709015792116 0.447569080581744 GO:0019865 immunoglobulin binding 3/862 26/18639 0.115384615384615 2.49495805818312 0.116709015792116 0.447569080581744 GO:0070412 R-SMAD binding 3/862 26/18639 0.115384615384615 2.49495805818312 0.116709015792116 0.447569080581744 GO:0120014 phospholipid transfer activity 3/862 26/18639 0.115384615384615 2.49495805818312 0.116709015792116 0.447569080581744 GO:0019855 calcium channel inhibitor activity 2/862 13/18639 0.153846153846154 3.32661074424416 0.118999122843572 0.447569080581744 GO:0030955 potassium ion binding 2/862 13/18639 0.153846153846154 3.32661074424416 0.118999122843572 0.447569080581744 GO:0032396 inhibitory MHC class I receptor activity 2/862 13/18639 0.153846153846154 3.32661074424416 0.118999122843572 0.447569080581744 GO:0071837 HMG box domain binding 2/862 13/18639 0.153846153846154 3.32661074424416 0.118999122843572 0.447569080581744 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/862 13/18639 0.153846153846154 3.32661074424416 0.118999122843572 0.447569080581744 GO:0097157 pre-mRNA intronic binding 2/862 13/18639 0.153846153846154 3.32661074424416 0.118999122843572 0.447569080581744 GO:0140666 annealing activity 2/862 13/18639 0.153846153846154 3.32661074424416 0.118999122843572 0.447569080581744 GO:0042287 MHC protein binding 4/862 41/18639 0.0975609756097561 2.10955803293532 0.119884575155824 0.447569080581744 GO:0061650 ubiquitin-like protein conjugating enzyme activity 4/862 41/18639 0.0975609756097561 2.10955803293532 0.119884575155824 0.447569080581744 GO:0140318 protein transporter activity 4/862 41/18639 0.0975609756097561 2.10955803293532 0.119884575155824 0.447569080581744 GO:0015932 nucleobase-containing compound transmembrane transporter activity 5/862 57/18639 0.087719298245614 1.89675174013921 0.122698965248031 0.454883968724407 GO:0016504 peptidase activator activity 5/862 57/18639 0.087719298245614 1.89675174013921 0.122698965248031 0.454883968724407 GO:0001671 ATPase activator activity 3/862 27/18639 0.111111111111111 2.40255220417633 0.127025262989349 0.468327453547314 GO:0005496 steroid binding 8/862 108/18639 0.0740740740740741 1.60170146945089 0.127205483153359 0.468327453547314 GO:0042056 chemoattractant activity 4/862 42/18639 0.0952380952380952 2.05933046072257 0.127948038925007 0.469436942814507 GO:0019903 protein phosphatase binding 10/862 144/18639 0.0694444444444444 1.50159512761021 0.130805430774417 0.473186903187354 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 21/862 349/18639 0.0601719197707736 1.30109560627314 0.132371893720607 0.473186903187354 GO:0019003 GDP binding 6/862 75/18639 0.08 1.72983758700696 0.133054353916722 0.473186903187354 GO:0005545 1-phosphatidylinositol binding 2/862 14/18639 0.142857142857143 3.08899569108386 0.134751533520459 0.473186903187354 GO:0008191 metalloendopeptidase inhibitor activity 2/862 14/18639 0.142857142857143 3.08899569108386 0.134751533520459 0.473186903187354 GO:0008474 palmitoyl-(protein) hydrolase activity 2/862 14/18639 0.142857142857143 3.08899569108386 0.134751533520459 0.473186903187354 GO:0008559 ABC-type xenobiotic transporter activity 2/862 14/18639 0.142857142857143 3.08899569108386 0.134751533520459 0.473186903187354 GO:0031404 chloride ion binding 2/862 14/18639 0.142857142857143 3.08899569108386 0.134751533520459 0.473186903187354 GO:0034236 protein kinase A catalytic subunit binding 2/862 14/18639 0.142857142857143 3.08899569108386 0.134751533520459 0.473186903187354 GO:0042043 neurexin family protein binding 2/862 14/18639 0.142857142857143 3.08899569108386 0.134751533520459 0.473186903187354 GO:0071933 Arp2/3 complex binding 2/862 14/18639 0.142857142857143 3.08899569108386 0.134751533520459 0.473186903187354 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 2/862 14/18639 0.142857142857143 3.08899569108386 0.134751533520459 0.473186903187354 GO:0098599 palmitoyl hydrolase activity 2/862 14/18639 0.142857142857143 3.08899569108386 0.134751533520459 0.473186903187354 GO:0008375 acetylglucosaminyltransferase activity 4/862 43/18639 0.0930232558139535 2.01143905465926 0.136231132448037 0.475245655490857 GO:0048156 tau protein binding 4/862 43/18639 0.0930232558139535 2.01143905465926 0.136231132448037 0.475245655490857 GO:0004222 metalloendopeptidase activity 8/862 110/18639 0.0727272727272727 1.57257962455178 0.137066437748043 0.475527142656966 GO:0051537 2 iron, 2 sulfur cluster binding 3/862 28/18639 0.107142857142857 2.31674676831289 0.137652593927016 0.475527142656966 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 3/862 28/18639 0.107142857142857 2.31674676831289 0.137652593927016 0.475527142656966 GO:0051536 iron-sulfur cluster binding 6/862 76/18639 0.0789473684210526 1.70707656612529 0.139190424402474 0.479283532570331 GO:0140297 DNA-binding transcription factor binding 28/862 488/18639 0.0573770491803279 1.24066220379598 0.141403997475208 0.485335010689102 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 5/862 60/18639 0.0833333333333333 1.80191415313225 0.143567365717692 0.491175810686893 GO:0051540 metal cluster binding 6/862 77/18639 0.0779220779220779 1.6849067405912 0.145455732118893 0.496041342866995 GO:0004629 phospholipase C activity 3/862 29/18639 0.103448275862069 2.2368589487159 0.148569170572245 0.498733008120098 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 3/862 29/18639 0.103448275862069 2.2368589487159 0.148569170572245 0.498733008120098 GO:0019905 syntaxin binding 5/862 61/18639 0.0819672131147541 1.77237457685139 0.150843550080604 0.498733008120098 GO:0015929 hexosaminidase activity 2/862 15/18639 0.133333333333333 2.8830626450116 0.150932357720556 0.498733008120098 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/862 15/18639 0.133333333333333 2.8830626450116 0.150932357720556 0.498733008120098 GO:0017081 chloride channel regulator activity 2/862 15/18639 0.133333333333333 2.8830626450116 0.150932357720556 0.498733008120098 GO:0031386 protein tag activity 2/862 15/18639 0.133333333333333 2.8830626450116 0.150932357720556 0.498733008120098 GO:0034483 heparan sulfate sulfotransferase activity 2/862 15/18639 0.133333333333333 2.8830626450116 0.150932357720556 0.498733008120098 GO:0050780 dopamine receptor binding 2/862 15/18639 0.133333333333333 2.8830626450116 0.150932357720556 0.498733008120098 GO:0141047 molecular tag activity 2/862 15/18639 0.133333333333333 2.8830626450116 0.150932357720556 0.498733008120098 GO:0019199 transmembrane receptor protein kinase activity 6/862 78/18639 0.0769230769230769 1.66330537212208 0.151847136944517 0.500202333464291 GO:0004180 carboxypeptidase activity 4/862 46/18639 0.0869565217391304 1.8802582467467 0.162304572740307 0.531360201217496 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 4/862 46/18639 0.0869565217391304 1.8802582467467 0.162304572740307 0.531360201217496 GO:0035401 histone H3Y41 kinase activity 8/862 115/18639 0.0695652173913043 1.50420659739736 0.163324833768075 0.531430040150555 GO:0140801 histone H2AXY142 kinase activity 8/862 115/18639 0.0695652173913043 1.50420659739736 0.163324833768075 0.531430040150555 GO:0048306 calcium-dependent protein binding 6/862 80/18639 0.075 1.62172273781903 0.164994992887822 0.535094238014245 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 2/862 16/18639 0.125 2.70287122969838 0.167468403438669 0.535094238014245 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/862 16/18639 0.125 2.70287122969838 0.167468403438669 0.535094238014245 GO:0017070 U6 snRNA binding 2/862 16/18639 0.125 2.70287122969838 0.167468403438669 0.535094238014245 GO:0022858 alanine transmembrane transporter activity 2/862 16/18639 0.125 2.70287122969838 0.167468403438669 0.535094238014245 GO:0097027 ubiquitin-protein transferase activator activity 2/862 16/18639 0.125 2.70287122969838 0.167468403438669 0.535094238014245 GO:0016411 acylglycerol O-acyltransferase activity 3/862 31/18639 0.0967741935483871 2.09254546815358 0.171182893231069 0.545325144903766 GO:0042578 phosphoric ester hydrolase activity 21/862 363/18639 0.0578512396694215 1.25091561043892 0.172870584653746 0.549057618124138 GO:0005506 iron ion binding 10/862 154/18639 0.0649350649350649 1.40408895049266 0.176531361259751 0.559015977322545 GO:0140104 molecular carrier activity 15/862 249/18639 0.0602409638554217 1.30258854443295 0.179702609195311 0.566868755381806 GO:0005085 guanyl-nucleotide exchange factor activity 14/862 230/18639 0.0608695652173913 1.31618077272269 0.180082245366166 0.566868755381806 GO:0032266 phosphatidylinositol-3-phosphate binding 4/862 48/18639 0.0833333333333333 1.80191415313225 0.180609500069955 0.566868755381806 GO:0019843 rRNA binding 5/862 65/18639 0.0769230769230769 1.66330537212208 0.181407177307773 0.567697754869029 GO:0047498 calcium-dependent phospholipase A2 activity 3/862 32/18639 0.09375 2.02715342227378 0.182836854911478 0.570493881600622 GO:0070492 oligosaccharide binding 2/862 17/18639 0.117647058823529 2.543878804422 0.184292318244566 0.573353878983094 GO:0005004 GPI-linked ephrin receptor activity 4/862 49/18639 0.0816326530612245 1.76514039490506 0.190008682597597 0.574344426942736 GO:0005008 hepatocyte growth factor receptor activity 4/862 49/18639 0.0816326530612245 1.76514039490506 0.190008682597597 0.574344426942736 GO:0005009 insulin receptor activity 4/862 49/18639 0.0816326530612245 1.76514039490506 0.190008682597597 0.574344426942736 GO:0005011 macrophage colony-stimulating factor receptor activity 4/862 49/18639 0.0816326530612245 1.76514039490506 0.190008682597597 0.574344426942736 GO:0005018 platelet-derived growth factor alpha-receptor activity 4/862 49/18639 0.0816326530612245 1.76514039490506 0.190008682597597 0.574344426942736 GO:0005020 stem cell factor receptor activity 4/862 49/18639 0.0816326530612245 1.76514039490506 0.190008682597597 0.574344426942736 GO:0008288 boss receptor activity 4/862 49/18639 0.0816326530612245 1.76514039490506 0.190008682597597 0.574344426942736 GO:0036332 placental growth factor receptor activity 4/862 49/18639 0.0816326530612245 1.76514039490506 0.190008682597597 0.574344426942736 GO:0038062 protein tyrosine kinase collagen receptor activity 4/862 49/18639 0.0816326530612245 1.76514039490506 0.190008682597597 0.574344426942736 GO:0060175 brain-derived neurotrophic factor receptor activity 4/862 49/18639 0.0816326530612245 1.76514039490506 0.190008682597597 0.574344426942736 GO:0051117 ATPase binding 6/862 84/18639 0.0714285714285714 1.54449784554193 0.192651410840201 0.580683006045251 GO:0016500 protein-hormone receptor activity 5/862 67/18639 0.0746268656716418 1.61365446549157 0.197484687006307 0.583727814580476 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5/862 67/18639 0.0746268656716418 1.61365446549157 0.197484687006307 0.583727814580476 GO:0005006 epidermal growth factor receptor activity 4/862 50/18639 0.08 1.72983758700696 0.19955875501197 0.583727814580476 GO:0005007 fibroblast growth factor receptor activity 4/862 50/18639 0.08 1.72983758700696 0.19955875501197 0.583727814580476 GO:0005017 platelet-derived growth factor receptor activity 4/862 50/18639 0.08 1.72983758700696 0.19955875501197 0.583727814580476 GO:0005019 platelet-derived growth factor beta-receptor activity 4/862 50/18639 0.08 1.72983758700696 0.19955875501197 0.583727814580476 GO:0015605 organophosphate ester transmembrane transporter activity 4/862 50/18639 0.08 1.72983758700696 0.19955875501197 0.583727814580476 GO:0000400 four-way junction DNA binding 2/862 18/18639 0.111111111111111 2.40255220417633 0.201342206720897 0.583727814580476 GO:0000900 mRNA regulatory element binding translation repressor activity 2/862 18/18639 0.111111111111111 2.40255220417633 0.201342206720897 0.583727814580476 GO:0022851 GABA-gated chloride ion channel activity 2/862 18/18639 0.111111111111111 2.40255220417633 0.201342206720897 0.583727814580476 GO:0032393 MHC class I receptor activity 2/862 18/18639 0.111111111111111 2.40255220417633 0.201342206720897 0.583727814580476 GO:0050811 GABA receptor binding 2/862 18/18639 0.111111111111111 2.40255220417633 0.201342206720897 0.583727814580476 GO:1901611 phosphatidylglycerol binding 2/862 18/18639 0.111111111111111 2.40255220417633 0.201342206720897 0.583727814580476 GO:1990381 ubiquitin-specific protease binding 2/862 18/18639 0.111111111111111 2.40255220417633 0.201342206720897 0.583727814580476 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 3/862 34/18639 0.0882352941176471 1.9079091033165 0.206733123240143 0.597164730254838 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/862 86/18639 0.0697674418604651 1.50857929099444 0.207099422428605 0.597164730254838 GO:0005010 insulin-like growth factor receptor activity 4/862 51/18639 0.0784313725490196 1.695919202948 0.209249474299128 0.598498496382453 GO:0005030 neurotrophin receptor activity 4/862 51/18639 0.0784313725490196 1.695919202948 0.209249474299128 0.598498496382453 GO:0005272 sodium channel activity 4/862 51/18639 0.0784313725490196 1.695919202948 0.209249474299128 0.598498496382453 GO:0003712 transcription coregulator activity 27/862 495/18639 0.0545454545454545 1.17943471841384 0.213303357133927 0.608457833754687 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 2/862 19/18639 0.105263157894737 2.27610208816705 0.218561270731822 0.613015849098179 GO:0004890 GABA-A receptor activity 2/862 19/18639 0.105263157894737 2.27610208816705 0.218561270731822 0.613015849098179 GO:0031420 alkali metal ion binding 2/862 19/18639 0.105263157894737 2.27610208816705 0.218561270731822 0.613015849098179 GO:0070003 threonine-type peptidase activity 2/862 19/18639 0.105263157894737 2.27610208816705 0.218561270731822 0.613015849098179 GO:0097001 ceramide binding 2/862 19/18639 0.105263157894737 2.27610208816705 0.218561270731822 0.613015849098179 GO:1990380 K48-linked deubiquitinase activity 2/862 19/18639 0.105263157894737 2.27610208816705 0.218561270731822 0.613015849098179 GO:0005154 epidermal growth factor receptor binding 3/862 35/18639 0.0857142857142857 1.85339741465031 0.218934231820778 0.613015849098179 GO:0008028 monocarboxylic acid transmembrane transporter activity 5/862 70/18639 0.0714285714285714 1.54449784554193 0.222461387259887 0.621256997492179 GO:0005003 ephrin receptor activity 4/862 53/18639 0.0754716981132075 1.63192225189336 0.229011895564429 0.631265950467751 GO:0005005 transmembrane-ephrin receptor activity 4/862 53/18639 0.0754716981132075 1.63192225189336 0.229011895564429 0.631265950467751 GO:0008146 sulfotransferase activity 4/862 53/18639 0.0754716981132075 1.63192225189336 0.229011895564429 0.631265950467751 GO:0016860 intramolecular oxidoreductase activity 4/862 53/18639 0.0754716981132075 1.63192225189336 0.229011895564429 0.631265950467751 GO:0038064 collagen receptor activity 4/862 53/18639 0.0754716981132075 1.63192225189336 0.229011895564429 0.631265950467751 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/862 36/18639 0.0833333333333333 1.80191415313225 0.231277298335829 0.635863166484036 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/862 20/18639 0.1 2.1622969837587 0.235897471232616 0.645861980355027 GO:0003714 transcription corepressor activity 12/862 204/18639 0.0588235294117647 1.271939402211 0.236128111238821 0.645861980355027 GO:0050661 NADP binding 4/862 54/18639 0.0740740740740741 1.60170146945089 0.239063211039518 0.652213478323198 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 8/862 128/18639 0.0625 1.35143561484919 0.240957245011086 0.655699510720705 GO:0043539 protein serine/threonine kinase activator activity 5/862 73/18639 0.0684931506849315 1.48102533134158 0.248322548235475 0.670434367826966 GO:0031406 carboxylic acid binding 11/862 187/18639 0.0588235294117647 1.271939402211 0.248712578010343 0.670434367826966 GO:0008374 O-acyltransferase activity 4/862 55/18639 0.0727272727272727 1.57257962455178 0.249214452710329 0.670434367826966 GO:0098632 cell-cell adhesion mediator activity 4/862 55/18639 0.0727272727272727 1.57257962455178 0.249214452710329 0.670434367826966 GO:0052689 carboxylic ester hydrolase activity 6/862 92/18639 0.0652173913043478 1.41019368506002 0.252533584011487 0.670434367826966 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/862 21/18639 0.0952380952380952 2.05933046072257 0.25330321040079 0.670434367826966 GO:0005248 voltage-gated sodium channel activity 2/862 21/18639 0.0952380952380952 2.05933046072257 0.25330321040079 0.670434367826966 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/862 21/18639 0.0952380952380952 2.05933046072257 0.25330321040079 0.670434367826966 GO:0010314 phosphatidylinositol-5-phosphate binding 2/862 21/18639 0.0952380952380952 2.05933046072257 0.25330321040079 0.670434367826966 GO:0019200 carbohydrate kinase activity 2/862 21/18639 0.0952380952380952 2.05933046072257 0.25330321040079 0.670434367826966 GO:0036122 BMP binding 2/862 21/18639 0.0952380952380952 2.05933046072257 0.25330321040079 0.670434367826966 GO:0042887 amide transmembrane transporter activity 3/862 38/18639 0.0789473684210526 1.70707656612529 0.256312406380282 0.676715633718661 GO:0170055 lipid transmembrane transporter activity 4/862 56/18639 0.0714285714285714 1.54449784554193 0.25945563416721 0.681714094689214 GO:0043177 organic acid binding 11/862 189/18639 0.0582010582010582 1.25847972599713 0.259487037922116 0.681714094689214 GO:0141108 transporter regulator activity 10/862 170/18639 0.0588235294117647 1.271939402211 0.262393210704167 0.687651172879886 GO:0008093 cytoskeletal anchor activity 2/862 22/18639 0.0909090909090909 1.96572453068973 0.270735032935748 0.702590426935697 GO:0015377 chloride:monoatomic cation symporter activity 2/862 22/18639 0.0909090909090909 1.96572453068973 0.270735032935748 0.702590426935697 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 2/862 22/18639 0.0909090909090909 1.96572453068973 0.270735032935748 0.702590426935697 GO:0016881 acid-amino acid ligase activity 2/862 22/18639 0.0909090909090909 1.96572453068973 0.270735032935748 0.702590426935697 GO:0098631 cell adhesion mediator activity 5/862 76/18639 0.0657894736842105 1.42256380510441 0.274899767622878 0.711662658760929 GO:0004867 serine-type endopeptidase inhibitor activity 6/862 95/18639 0.0631578947368421 1.36566125290023 0.276216762322968 0.713336492989413 GO:0051087 protein-folding chaperone binding 8/862 134/18639 0.0597014925373134 1.29092357239325 0.280376472750069 0.722213752186942 GO:0061791 GTPase motor activity 3/862 40/18639 0.075 1.62172273781903 0.281690514245847 0.722213752186942 GO:1990606 membrane scission GTPase motor activity 3/862 40/18639 0.075 1.62172273781903 0.281690514245847 0.722213752186942 GO:0003724 RNA helicase activity 5/862 77/18639 0.0649350649350649 1.40408895049266 0.283888936755099 0.723101791379766 GO:0004896 cytokine receptor activity 6/862 96/18639 0.0625 1.35143561484919 0.284225585135033 0.723101791379766 GO:0008236 serine-type peptidase activity 11/862 194/18639 0.0567010309278351 1.22604468151267 0.287077289259432 0.723101791379766 GO:0005158 insulin receptor binding 2/862 23/18639 0.0869565217391304 1.8802582467467 0.28815334543705 0.723101791379766 GO:0016917 GABA receptor activity 2/862 23/18639 0.0869565217391304 1.8802582467467 0.28815334543705 0.723101791379766 GO:0017134 fibroblast growth factor binding 2/862 23/18639 0.0869565217391304 1.8802582467467 0.28815334543705 0.723101791379766 GO:0042171 lysophosphatidic acid acyltransferase activity 2/862 23/18639 0.0869565217391304 1.8802582467467 0.28815334543705 0.723101791379766 GO:0070577 lysine-acetylated histone binding 2/862 23/18639 0.0869565217391304 1.8802582467467 0.28815334543705 0.723101791379766 GO:0071617 lysophospholipid acyltransferase activity 2/862 23/18639 0.0869565217391304 1.8802582467467 0.28815334543705 0.723101791379766 GO:0036002 pre-mRNA binding 4/862 59/18639 0.0677966101694915 1.46596405678556 0.290620917380448 0.727578014335993 GO:0004721 phosphoprotein phosphatase activity 10/862 175/18639 0.0571428571428571 1.23559827643354 0.291684689904077 0.728527018915346 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/862 41/18639 0.0731707317073171 1.58216852470149 0.294464667331901 0.732033658974633 GO:0017080 sodium channel regulator activity 3/862 41/18639 0.0731707317073171 1.58216852470149 0.294464667331901 0.732033658974633 GO:0004252 serine-type endopeptidase activity 10/862 176/18639 0.0568181818181818 1.22857783168108 0.29764876487019 0.73380489980162 GO:0008170 N-methyltransferase activity 6/862 98/18639 0.0612244897959184 1.3238552961788 0.300388992263108 0.73380489980162 GO:0008186 ATP-dependent activity, acting on RNA 5/862 79/18639 0.0632911392405063 1.36854239478399 0.302025566969772 0.73380489980162 GO:0016835 carbon-oxygen lyase activity 5/862 79/18639 0.0632911392405063 1.36854239478399 0.302025566969772 0.73380489980162 GO:0033293 monocarboxylic acid binding 5/862 79/18639 0.0632911392405063 1.36854239478399 0.302025566969772 0.73380489980162 GO:0005540 hyaluronic acid binding 2/862 24/18639 0.0833333333333333 1.80191415313225 0.305522152830938 0.73380489980162 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/862 24/18639 0.0833333333333333 1.80191415313225 0.305522152830938 0.73380489980162 GO:0030215 semaphorin receptor binding 2/862 24/18639 0.0833333333333333 1.80191415313225 0.305522152830938 0.73380489980162 GO:0035035 histone acetyltransferase binding 2/862 24/18639 0.0833333333333333 1.80191415313225 0.305522152830938 0.73380489980162 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/862 24/18639 0.0833333333333333 1.80191415313225 0.305522152830938 0.73380489980162 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/862 24/18639 0.0833333333333333 1.80191415313225 0.305522152830938 0.73380489980162 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/862 24/18639 0.0833333333333333 1.80191415313225 0.305522152830938 0.73380489980162 GO:0048027 mRNA 5'-UTR binding 2/862 24/18639 0.0833333333333333 1.80191415313225 0.305522152830938 0.73380489980162 GO:0050699 WW domain binding 2/862 24/18639 0.0833333333333333 1.80191415313225 0.305522152830938 0.73380489980162 GO:0140033 acetylation-dependent protein binding 2/862 24/18639 0.0833333333333333 1.80191415313225 0.305522152830938 0.73380489980162 GO:0017171 serine hydrolase activity 11/862 198/18639 0.0555555555555556 1.20127610208817 0.309731198043377 0.742238726842687 GO:0016836 hydro-lyase activity 4/862 61/18639 0.0655737704918033 1.41789966148112 0.311670791089996 0.745208363415182 GO:0030295 protein kinase activator activity 8/862 139/18639 0.0575539568345324 1.24448747266688 0.314430375848242 0.748442773831161 GO:0070851 growth factor receptor binding 8/862 139/18639 0.0575539568345324 1.24448747266688 0.314430375848242 0.748442773831161 GO:0043130 ubiquitin binding 6/862 100/18639 0.06 1.29737819025522 0.316718190915979 0.75220570342545 GO:0016829 lyase activity 11/862 200/18639 0.055 1.18926334106729 0.321220989274681 0.756538710940629 GO:0015179 L-amino acid transmembrane transporter activity 4/862 62/18639 0.0645161290322581 1.39503031210239 0.322250077345101 0.756538710940629 GO:0008483 transaminase activity 2/862 25/18639 0.08 1.72983758700696 0.322808810871283 0.756538710940629 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/862 25/18639 0.08 1.72983758700696 0.322808810871283 0.756538710940629 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/862 25/18639 0.08 1.72983758700696 0.322808810871283 0.756538710940629 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/862 25/18639 0.08 1.72983758700696 0.322808810871283 0.756538710940629 GO:0015108 chloride transmembrane transporter activity 7/862 121/18639 0.0578512396694215 1.25091561043892 0.327290199136331 0.765355542595728 GO:0005507 copper ion binding 4/862 63/18639 0.0634920634920635 1.37288697381505 0.332853832066003 0.775146828586655 GO:0016790 thiolester hydrolase activity 3/862 44/18639 0.0681818181818182 1.4742933980173 0.332934305135434 0.775146828586655 GO:0001637 G protein-coupled chemoattractant receptor activity 2/862 26/18639 0.0769230769230769 1.66330537212208 0.339983793794547 0.781230225448963 GO:0004529 DNA exonuclease activity 2/862 26/18639 0.0769230769230769 1.66330537212208 0.339983793794547 0.781230225448963 GO:0004950 chemokine receptor activity 2/862 26/18639 0.0769230769230769 1.66330537212208 0.339983793794547 0.781230225448963 GO:0005160 transforming growth factor beta receptor binding 2/862 26/18639 0.0769230769230769 1.66330537212208 0.339983793794547 0.781230225448963 GO:0030247 polysaccharide binding 2/862 26/18639 0.0769230769230769 1.66330537212208 0.339983793794547 0.781230225448963 GO:0046915 transition metal ion transmembrane transporter activity 3/862 45/18639 0.0666666666666667 1.4415313225058 0.345756826339952 0.781230225448963 GO:0051539 4 iron, 4 sulfur cluster binding 3/862 45/18639 0.0666666666666667 1.4415313225058 0.345756826339952 0.781230225448963 GO:0015103 inorganic anion transmembrane transporter activity 9/862 165/18639 0.0545454545454545 1.17943471841384 0.354549376414006 0.781230225448963 GO:0004364 glutathione transferase activity 2/862 27/18639 0.0740740740740741 1.60170146945089 0.357020476258963 0.781230225448963 GO:0035255 ionotropic glutamate receptor binding 2/862 27/18639 0.0740740740740741 1.60170146945089 0.357020476258963 0.781230225448963 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/862 27/18639 0.0740740740740741 1.60170146945089 0.357020476258963 0.781230225448963 GO:0008514 organic anion transmembrane transporter activity 14/862 269/18639 0.0520446096654275 1.12535902500453 0.363723755976634 0.781230225448963 GO:0046943 carboxylic acid transmembrane transporter activity 10/862 188/18639 0.0531914893617021 1.15015797008442 0.371180103127071 0.781230225448963 GO:0005504 fatty acid binding 3/862 47/18639 0.0638297872340425 1.3801895641013 0.371318393810554 0.781230225448963 GO:0099095 ligand-gated monoatomic anion channel activity 3/862 47/18639 0.0638297872340425 1.3801895641013 0.371318393810554 0.781230225448963 GO:0045499 chemorepellent activity 2/862 28/18639 0.0714285714285714 1.54449784554193 0.373894928746035 0.781230225448963 GO:0046625 sphingolipid binding 2/862 28/18639 0.0714285714285714 1.54449784554193 0.373894928746035 0.781230225448963 GO:0046875 ephrin receptor binding 2/862 28/18639 0.0714285714285714 1.54449784554193 0.373894928746035 0.781230225448963 GO:0050698 proteoglycan sulfotransferase activity 2/862 28/18639 0.0714285714285714 1.54449784554193 0.373894928746035 0.781230225448963 GO:0051019 mitogen-activated protein kinase binding 2/862 28/18639 0.0714285714285714 1.54449784554193 0.373894928746035 0.781230225448963 GO:0016247 channel regulator activity 9/862 168/18639 0.0535714285714286 1.15837338415645 0.374341630350094 0.781230225448963 GO:0050840 extracellular matrix binding 4/862 67/18639 0.0597014925373134 1.29092357239325 0.375346273588471 0.781230225448963 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0004955 prostaglandin receptor activity 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0005031 tumor necrosis factor receptor activity 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0005131 growth hormone receptor binding 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0005337 nucleoside transmembrane transporter activity 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0005522 profilin binding 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0015187 glycine transmembrane transporter activity 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0015203 polyamine transmembrane transporter activity 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0016868 intramolecular phosphotransferase activity 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0031434 mitogen-activated protein kinase kinase binding 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0031996 thioesterase binding 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0032052 bile acid binding 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0033204 ribonuclease P RNA binding 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0043121 neurotrophin binding 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0043208 glycosphingolipid binding 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0043295 glutathione binding 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0051378 serotonin binding 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0051880 G-quadruplex DNA binding 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0070097 delta-catenin binding 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0070513 death domain binding 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0140940 histone H2A methyltransferase activity 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0141109 transporter activator activity 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:1990259 histone H2AQ104 methyltransferase activity 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:1990757 ubiquitin ligase activator activity 1/862 10/18639 0.1 2.1622969837587 0.377258539179719 0.781230225448963 GO:0005342 organic acid transmembrane transporter activity 10/862 189/18639 0.0529100529100529 1.14407247817921 0.377419939172041 0.781230225448963 GO:0019209 kinase activator activity 8/862 148/18639 0.0540540540540541 1.16880918041011 0.377434926623507 0.781230225448963 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/862 48/18639 0.0625 1.35143561484919 0.384032320059928 0.781230225448963 GO:0008509 monoatomic anion transmembrane transporter activity 8/862 149/18639 0.0536912751677852 1.1609648234946 0.384509060678378 0.781230225448963 GO:0005548 phospholipid transporter activity 4/862 68/18639 0.0588235294117647 1.271939402211 0.385949063220432 0.781230225448963 GO:1990841 promoter-specific chromatin binding 4/862 68/18639 0.0588235294117647 1.271939402211 0.385949063220432 0.781230225448963 GO:0003785 actin monomer binding 2/862 29/18639 0.0689655172413793 1.49123929914393 0.390585725647798 0.781230225448963 GO:0035250 UDP-galactosyltransferase activity 2/862 29/18639 0.0689655172413793 1.49123929914393 0.390585725647798 0.781230225448963 GO:0019842 vitamin binding 8/862 150/18639 0.0533333333333333 1.15322505800464 0.391589079112615 0.781230225448963 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 5/862 89/18639 0.0561797752808989 1.21477358638129 0.394351401706565 0.781230225448963 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 5/862 89/18639 0.0561797752808989 1.21477358638129 0.394351401706565 0.781230225448963 GO:0005126 cytokine receptor binding 14/862 275/18639 0.0509090909090909 1.10080573718625 0.394941548294724 0.781230225448963 GO:0016763 pentosyltransferase activity 3/862 49/18639 0.0612244897959184 1.3238552961788 0.396686035546602 0.781230225448963 GO:0035254 glutamate receptor binding 3/862 49/18639 0.0612244897959184 1.3238552961788 0.396686035546602 0.781230225448963 GO:0000510 H3-H4 histone complex chaperone activity 8/862 151/18639 0.0529801324503311 1.14558780596487 0.398672640331653 0.781230225448963 GO:0140584 chromatin extrusion motor activity 8/862 151/18639 0.0529801324503311 1.14558780596487 0.398672640331653 0.781230225448963 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 8/862 151/18639 0.0529801324503311 1.14558780596487 0.398672640331653 0.781230225448963 GO:0140849 ATP-dependent H2AZ histone chaperone activity 8/862 151/18639 0.0529801324503311 1.14558780596487 0.398672640331653 0.781230225448963 GO:0019887 protein kinase regulator activity 13/862 255/18639 0.0509803921568627 1.1023474819162 0.399582434561804 0.781230225448963 GO:0140793 histone H2AXY142 phosphatase activity 5/862 90/18639 0.0555555555555556 1.20127610208817 0.403603010023935 0.781230225448963 GO:0015616 DNA translocase activity 8/862 152/18639 0.0526315789473684 1.13805104408353 0.40575743080348 0.781230225448963 GO:0140674 ATP-dependent histone chaperone activity 8/862 152/18639 0.0526315789473684 1.13805104408353 0.40575743080348 0.781230225448963 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0004016 adenylate cyclase activity 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0004954 prostanoid receptor activity 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0005114 type II transforming growth factor beta receptor binding 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0005225 volume-sensitive anion channel activity 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0005536 D-glucose binding 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0008046 axon guidance receptor activity 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0008271 secondary active sulfate transmembrane transporter activity 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0008503 benzodiazepine receptor activity 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0010854 adenylate cyclase regulator activity 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0047676 arachidonate-CoA ligase activity 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0050786 RAGE receptor binding 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0050998 nitric-oxide synthase binding 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0070697 activin receptor binding 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0070990 snRNP binding 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0140031 phosphorylation-dependent protein binding 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0140537 transcription regulator activator activity 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:1900750 oligopeptide binding 1/862 11/18639 0.0909090909090909 1.96572453068973 0.406073995684474 0.781230225448963 GO:0016782 transferase activity, transferring sulphur-containing groups 4/862 70/18639 0.0571428571428571 1.23559827643354 0.407078279983853 0.781230225448963 GO:0140030 modification-dependent protein binding 9/862 173/18639 0.0520231213872832 1.12489438461435 0.407502608199412 0.781230225448963 GO:0016741 transferase activity, transferring one-carbon groups 11/862 215/18639 0.0511627906976744 1.10629148006259 0.409573541801494 0.783788216684874 GO:0061775 cohesin loader activity 8/862 153/18639 0.0522875816993464 1.13061280196533 0.412841166729467 0.788556009444428 GO:0005164 tumor necrosis factor receptor binding 2/862 31/18639 0.0645161290322581 1.39503031210239 0.423342101311344 0.788556009444428 GO:0008327 methyl-CpG binding 2/862 31/18639 0.0645161290322581 1.39503031210239 0.423342101311344 0.788556009444428 GO:0017147 Wnt-protein binding 2/862 31/18639 0.0645161290322581 1.39503031210239 0.423342101311344 0.788556009444428 GO:0070273 phosphatidylinositol-4-phosphate binding 2/862 31/18639 0.0645161290322581 1.39503031210239 0.423342101311344 0.788556009444428 GO:0004386 helicase activity 8/862 155/18639 0.0516129032258065 1.11602424968191 0.426996497868268 0.788556009444428 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0004126 cytidine deaminase activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0004526 ribonuclease P activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0004859 phospholipase inhibitor activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0005049 nuclear export signal receptor activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0008504 monoamine transmembrane transporter activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0008603 cAMP-dependent protein kinase regulator activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0010853 cyclase activator activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0015132 prostaglandin transmembrane transporter activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0016208 AMP binding 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0016273 arginine N-methyltransferase activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0016274 protein-arginine N-methyltransferase activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0016423 tRNA (guanine) methyltransferase activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0017166 vinculin binding 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0034452 dynactin binding 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0035197 siRNA binding 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0036009 protein-glutamine N-methyltransferase activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0045295 gamma-catenin binding 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0070679 inositol 1,4,5 trisphosphate binding 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/862 12/18639 0.0833333333333333 1.80191415313225 0.43355758038063 0.788556009444428 GO:0008378 galactosyltransferase activity 2/862 32/18639 0.0625 1.35143561484919 0.439375784404669 0.792365821367064 GO:0022884 macromolecule transmembrane transporter activity 2/862 32/18639 0.0625 1.35143561484919 0.439375784404669 0.792365821367064 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/862 32/18639 0.0625 1.35143561484919 0.439375784404669 0.792365821367064 GO:0042910 xenobiotic transmembrane transporter activity 2/862 32/18639 0.0625 1.35143561484919 0.439375784404669 0.792365821367064 GO:0043425 bHLH transcription factor binding 2/862 32/18639 0.0625 1.35143561484919 0.439375784404669 0.792365821367064 GO:0140789 histone phosphatase activity 7/862 136/18639 0.0514705882352941 1.11294697693463 0.441332780873799 0.794548356767719 GO:0005544 calcium-dependent phospholipid binding 3/862 53/18639 0.0566037735849057 1.22394168892002 0.446490067182598 0.798036077368041 GO:0051018 protein kinase A binding 3/862 53/18639 0.0566037735849057 1.22394168892002 0.446490067182598 0.798036077368041 GO:0140658 ATP-dependent chromatin remodeler activity 8/862 158/18639 0.0506329113924051 1.09483391582719 0.448166369914714 0.798036077368041 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/862 33/18639 0.0606060606060606 1.31048302045982 0.455161714367606 0.798036077368041 GO:0019956 chemokine binding 2/862 33/18639 0.0606060606060606 1.31048302045982 0.455161714367606 0.798036077368041 GO:0030296 protein tyrosine kinase activator activity 2/862 33/18639 0.0606060606060606 1.31048302045982 0.455161714367606 0.798036077368041 GO:1990782 protein tyrosine kinase binding 6/862 117/18639 0.0512820512820513 1.10887024808139 0.457625147548728 0.798036077368041 GO:0019207 kinase regulator activity 14/862 287/18639 0.0487804878048781 1.05477901646766 0.457825059258363 0.798036077368041 GO:0017069 snRNA binding 3/862 54/18639 0.0555555555555556 1.20127610208817 0.45869164695572 0.798036077368041 GO:0004993 G protein-coupled serotonin receptor activity 1/862 13/18639 0.0769230769230769 1.66330537212208 0.459770785175384 0.798036077368041 GO:0005035 death receptor activity 1/862 13/18639 0.0769230769230769 1.66330537212208 0.459770785175384 0.798036077368041 GO:0005172 vascular endothelial growth factor receptor binding 1/862 13/18639 0.0769230769230769 1.66330537212208 0.459770785175384 0.798036077368041 GO:0005542 folic acid binding 1/862 13/18639 0.0769230769230769 1.66330537212208 0.459770785175384 0.798036077368041 GO:0031432 titin binding 1/862 13/18639 0.0769230769230769 1.66330537212208 0.459770785175384 0.798036077368041 GO:0035673 oligopeptide transmembrane transporter activity 1/862 13/18639 0.0769230769230769 1.66330537212208 0.459770785175384 0.798036077368041 GO:0039706 co-receptor binding 1/862 13/18639 0.0769230769230769 1.66330537212208 0.459770785175384 0.798036077368041 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/862 13/18639 0.0769230769230769 1.66330537212208 0.459770785175384 0.798036077368041 GO:0045159 myosin II binding 1/862 13/18639 0.0769230769230769 1.66330537212208 0.459770785175384 0.798036077368041 GO:0061459 L-arginine transmembrane transporter activity 1/862 13/18639 0.0769230769230769 1.66330537212208 0.459770785175384 0.798036077368041 GO:0071714 icosanoid transmembrane transporter activity 1/862 13/18639 0.0769230769230769 1.66330537212208 0.459770785175384 0.798036077368041 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/862 13/18639 0.0769230769230769 1.66330537212208 0.459770785175384 0.798036077368041 GO:0140852 histone ubiquitin ligase activity 1/862 13/18639 0.0769230769230769 1.66330537212208 0.459770785175384 0.798036077368041 GO:0003689 DNA clamp loader activity 8/862 160/18639 0.05 1.08114849187935 0.4622128923381 0.799665882028843 GO:0099106 ion channel regulator activity 8/862 160/18639 0.05 1.08114849187935 0.4622128923381 0.799665882028843 GO:0016887 ATP hydrolysis activity 20/862 417/18639 0.0479616306954436 1.03707289388907 0.466202307230096 0.805258530670165 GO:0008376 acetylgalactosaminyltransferase activity 2/862 34/18639 0.0588235294117647 1.271939402211 0.470688501313072 0.80906714926835 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 2/862 34/18639 0.0588235294117647 1.271939402211 0.470688501313072 0.80906714926835 GO:0090482 vitamin transmembrane transporter activity 2/862 34/18639 0.0588235294117647 1.271939402211 0.470688501313072 0.80906714926835 GO:0004725 protein tyrosine phosphatase activity 5/862 98/18639 0.0510204081632653 1.10321274681566 0.476625964845528 0.809150080314135 GO:0032182 ubiquitin-like protein binding 6/862 120/18639 0.05 1.08114849187935 0.48207196343699 0.809150080314135 GO:0030170 pyridoxal phosphate binding 3/862 56/18639 0.0535714285714286 1.15837338415645 0.482738449070464 0.809150080314135 GO:0004065 arylsulfatase activity 1/862 14/18639 0.0714285714285714 1.54449784554193 0.484772266071917 0.809150080314135 GO:0004705 JUN kinase activity 1/862 14/18639 0.0714285714285714 1.54449784554193 0.484772266071917 0.809150080314135 GO:0005161 platelet-derived growth factor receptor binding 1/862 14/18639 0.0714285714285714 1.54449784554193 0.484772266071917 0.809150080314135 GO:0008494 translation activator activity 1/862 14/18639 0.0714285714285714 1.54449784554193 0.484772266071917 0.809150080314135 GO:0015926 glucosidase activity 1/862 14/18639 0.0714285714285714 1.54449784554193 0.484772266071917 0.809150080314135 GO:0016530 metallochaperone activity 1/862 14/18639 0.0714285714285714 1.54449784554193 0.484772266071917 0.809150080314135 GO:0019992 diacylglycerol binding 1/862 14/18639 0.0714285714285714 1.54449784554193 0.484772266071917 0.809150080314135 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/862 14/18639 0.0714285714285714 1.54449784554193 0.484772266071917 0.809150080314135 GO:0042813 Wnt receptor activity 1/862 14/18639 0.0714285714285714 1.54449784554193 0.484772266071917 0.809150080314135 GO:0043176 amine binding 1/862 14/18639 0.0714285714285714 1.54449784554193 0.484772266071917 0.809150080314135 GO:0044548 S100 protein binding 1/862 14/18639 0.0714285714285714 1.54449784554193 0.484772266071917 0.809150080314135 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/862 14/18639 0.0714285714285714 1.54449784554193 0.484772266071917 0.809150080314135 GO:0061665 SUMO ligase activity 1/862 14/18639 0.0714285714285714 1.54449784554193 0.484772266071917 0.809150080314135 GO:1901474 azole transmembrane transporter activity 1/862 14/18639 0.0714285714285714 1.54449784554193 0.484772266071917 0.809150080314135 GO:1901612 cardiolipin binding 1/862 14/18639 0.0714285714285714 1.54449784554193 0.484772266071917 0.809150080314135 GO:0016229 steroid dehydrogenase activity 2/862 35/18639 0.0571428571428571 1.23559827643354 0.485946335827756 0.809150080314135 GO:0061631 ubiquitin conjugating enzyme activity 2/862 35/18639 0.0571428571428571 1.23559827643354 0.485946335827756 0.809150080314135 GO:0015081 sodium ion transmembrane transporter activity 8/862 164/18639 0.0487804878048781 1.05477901646766 0.490073624366305 0.80998338155729 GO:0140713 histone chaperone activity 8/862 164/18639 0.0487804878048781 1.05477901646766 0.490073624366305 0.80998338155729 GO:0070279 vitamin B6 binding 3/862 57/18639 0.0526315789473684 1.13805104408353 0.494569646674443 0.80998338155729 GO:0016791 phosphatase activity 13/862 273/18639 0.0476190476190476 1.02966523036129 0.497349367845619 0.80998338155729 GO:0000287 magnesium ion binding 11/862 230/18639 0.0478260869565217 1.03414203571068 0.498426026174727 0.80998338155729 GO:0005484 SNAP receptor activity 2/862 36/18639 0.0555555555555556 1.20127610208817 0.500926867444928 0.80998338155729 GO:0055106 ubiquitin-protein transferase regulator activity 2/862 36/18639 0.0555555555555556 1.20127610208817 0.500926867444928 0.80998338155729 GO:0001216 DNA-binding transcription activator activity 23/862 491/18639 0.0468431771894094 1.01288860746334 0.505498673653749 0.80998338155729 GO:0140597 protein carrier chaperone 9/862 188/18639 0.0478723404255319 1.03514217307597 0.506152219030627 0.80998338155729 GO:0008094 ATP-dependent activity, acting on DNA 10/862 210/18639 0.0476190476190476 1.02966523036129 0.508206956226149 0.80998338155729 GO:0008194 UDP-glycosyltransferase activity 7/862 145/18639 0.0482758620689655 1.04386750940075 0.508596812445901 0.80998338155729 GO:0000774 adenyl-nucleotide exchange factor activity 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0004089 carbonate dehydratase activity 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0004467 long-chain fatty acid-CoA ligase activity 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0004953 icosanoid receptor activity 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0015116 sulfate transmembrane transporter activity 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0016846 carbon-sulfur lyase activity 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0031005 filamin binding 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0033130 acetylcholine receptor binding 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0042809 nuclear vitamin D receptor binding 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0047372 monoacylglycerol lipase activity 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0048531 beta-1,3-galactosyltransferase activity 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0051371 muscle alpha-actinin binding 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0120283 protein serine/threonine kinase binding 1/862 15/18639 0.0666666666666667 1.4415313225058 0.5086179738113 0.80998338155729 GO:0001664 G protein-coupled receptor binding 14/862 297/18639 0.0471380471380471 1.01926457146875 0.50975189393239 0.80998338155729 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 8/862 167/18639 0.0479041916167665 1.03583089042333 0.510706694636491 0.80998338155729 GO:0016874 ligase activity 8/862 167/18639 0.0479041916167665 1.03583089042333 0.510706694636491 0.80998338155729 GO:0015171 amino acid transmembrane transporter activity 5/862 102/18639 0.0490196078431373 1.0599495018425 0.512051113947523 0.80998338155729 GO:0031593 polyubiquitin modification-dependent protein binding 3/862 59/18639 0.0508474576271186 1.09947304258917 0.517816575944727 0.80998338155729 GO:0070888 E-box binding 3/862 59/18639 0.0508474576271186 1.09947304258917 0.517816575944727 0.80998338155729 GO:0030971 receptor tyrosine kinase binding 4/862 81/18639 0.0493827160493827 1.06780097963393 0.519389032270758 0.80998338155729 GO:0005253 monoatomic anion channel activity 5/862 103/18639 0.0485436893203883 1.04965872997995 0.520755310205895 0.80998338155729 GO:0001217 DNA-binding transcription repressor activity 13/862 278/18639 0.0467625899280576 1.01114607154184 0.524009068183153 0.80998338155729 GO:0000146 microfilament motor activity 2/862 38/18639 0.0526315789473684 1.13805104408353 0.530029240099467 0.80998338155729 GO:0005501 retinoid binding 2/862 38/18639 0.0526315789473684 1.13805104408353 0.530029240099467 0.80998338155729 GO:0019840 isoprenoid binding 2/862 38/18639 0.0526315789473684 1.13805104408353 0.530029240099467 0.80998338155729 GO:0043531 ADP binding 2/862 38/18639 0.0526315789473684 1.13805104408353 0.530029240099467 0.80998338155729 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0004707 MAP kinase activity 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0004708 MAP kinase kinase activity 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0005149 interleukin-1 receptor binding 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0005159 insulin-like growth factor receptor binding 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0005521 lamin binding 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0008142 oxysterol binding 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0008296 3'-5'-DNA exonuclease activity 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0015562 efflux transmembrane transporter activity 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0019841 retinol binding 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0030275 LRR domain binding 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0034450 ubiquitin-ubiquitin ligase activity 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0055102 lipase inhibitor activity 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0070411 I-SMAD binding 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0140328 floppase activity 1/862 16/18639 0.0625 1.35143561484919 0.531361278502809 0.80998338155729 GO:0005254 chloride channel activity 4/862 83/18639 0.0481927710843374 1.04207083554636 0.538763600339184 0.81892067251556 GO:0030165 PDZ domain binding 4/862 83/18639 0.0481927710843374 1.04207083554636 0.538763600339184 0.81892067251556 GO:0046982 protein heterodimerization activity 17/862 369/18639 0.046070460704607 0.996180182219456 0.541956065659514 0.820709185751968 GO:0000217 DNA secondary structure binding 2/862 39/18639 0.0512820512820513 1.10887024808139 0.544140688182067 0.820709185751968 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/862 39/18639 0.0512820512820513 1.10887024808139 0.544140688182067 0.820709185751968 GO:0000149 SNARE binding 5/862 106/18639 0.0471698113207547 1.01995140743335 0.546454651778952 0.820709185751968 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/862 17/18639 0.0588235294117647 1.271939402211 0.553053088518949 0.820709185751968 GO:0004549 tRNA-specific ribonuclease activity 1/862 17/18639 0.0588235294117647 1.271939402211 0.553053088518949 0.820709185751968 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/862 17/18639 0.0588235294117647 1.271939402211 0.553053088518949 0.820709185751968 GO:0008484 sulfuric ester hydrolase activity 1/862 17/18639 0.0588235294117647 1.271939402211 0.553053088518949 0.820709185751968 GO:0015278 intracellularly gated calcium channel activity 1/862 17/18639 0.0588235294117647 1.271939402211 0.553053088518949 0.820709185751968 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/862 17/18639 0.0588235294117647 1.271939402211 0.553053088518949 0.820709185751968 GO:0016018 cyclosporin A binding 1/862 17/18639 0.0588235294117647 1.271939402211 0.553053088518949 0.820709185751968 GO:0017110 nucleoside diphosphate phosphatase activity 1/862 17/18639 0.0588235294117647 1.271939402211 0.553053088518949 0.820709185751968 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/862 17/18639 0.0588235294117647 1.271939402211 0.553053088518949 0.820709185751968 GO:0032977 membrane insertase activity 1/862 17/18639 0.0588235294117647 1.271939402211 0.553053088518949 0.820709185751968 GO:0036041 long-chain fatty acid binding 1/862 17/18639 0.0588235294117647 1.271939402211 0.553053088518949 0.820709185751968 GO:0045125 bioactive lipid receptor activity 1/862 17/18639 0.0588235294117647 1.271939402211 0.553053088518949 0.820709185751968 GO:1990226 histone methyltransferase binding 1/862 17/18639 0.0588235294117647 1.271939402211 0.553053088518949 0.820709185751968 GO:0003823 antigen binding 8/862 174/18639 0.0459770114942529 0.994159532762621 0.557697611366428 0.825678584097563 GO:0030331 nuclear estrogen receptor binding 2/862 40/18639 0.05 1.08114849187935 0.557953855231342 0.825678584097563 GO:0022824 transmitter-gated monoatomic ion channel activity 3/862 63/18639 0.0476190476190476 1.02966523036129 0.562505976946298 0.828572220293905 GO:0022835 transmitter-gated channel activity 3/862 63/18639 0.0476190476190476 1.02966523036129 0.562505976946298 0.828572220293905 GO:1901682 sulfur compound transmembrane transporter activity 3/862 63/18639 0.0476190476190476 1.02966523036129 0.562505976946298 0.828572220293905 GO:0016758 hexosyltransferase activity 9/862 197/18639 0.0456852791878173 0.987851413899914 0.563024168489186 0.828572220293905 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 22/862 484/18639 0.0454545454545455 0.982862265344864 0.564779066185216 0.830006804448992 GO:0003774 cytoskeletal motor activity 7/862 153/18639 0.0457516339869281 0.989286201719667 0.565927492713528 0.830547382409922 GO:0015291 secondary active transmembrane transporter activity 13/862 287/18639 0.0452961672473868 0.97943765814854 0.57085958310135 0.830559795387265 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/862 41/18639 0.0487804878048781 1.05477901646766 0.571466121277467 0.830559795387265 GO:0003746 translation elongation factor activity 1/862 18/18639 0.0555555555555556 1.20127610208817 0.573741963918834 0.830559795387265 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/862 18/18639 0.0555555555555556 1.20127610208817 0.573741963918834 0.830559795387265 GO:0004970 glutamate-gated receptor activity 1/862 18/18639 0.0555555555555556 1.20127610208817 0.573741963918834 0.830559795387265 GO:0008409 5'-3' exonuclease activity 1/862 18/18639 0.0555555555555556 1.20127610208817 0.573741963918834 0.830559795387265 GO:0015172 acidic amino acid transmembrane transporter activity 1/862 18/18639 0.0555555555555556 1.20127610208817 0.573741963918834 0.830559795387265 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/862 18/18639 0.0555555555555556 1.20127610208817 0.573741963918834 0.830559795387265 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/862 18/18639 0.0555555555555556 1.20127610208817 0.573741963918834 0.830559795387265 GO:0070628 proteasome binding 1/862 18/18639 0.0555555555555556 1.20127610208817 0.573741963918834 0.830559795387265 GO:0005179 hormone activity 6/862 132/18639 0.0454545454545455 0.982862265344864 0.575719387965334 0.832289984775972 GO:0043021 ribonucleoprotein complex binding 8/862 177/18639 0.0451977401129944 0.977309371190373 0.577244575870908 0.833362589859765 GO:0016757 glycosyltransferase activity 12/862 267/18639 0.0449438202247191 0.971818869105034 0.582179312644894 0.839347952105918 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 12/862 268/18639 0.0447761194029851 0.968192679294941 0.587420315359832 0.845323393613305 GO:0003756 protein disulfide isomerase activity 1/862 19/18639 0.0526315789473684 1.13805104408353 0.593474224651446 0.845323393613305 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/862 19/18639 0.0526315789473684 1.13805104408353 0.593474224651446 0.845323393613305 GO:0005229 intracellularly calcium-gated chloride channel activity 1/862 19/18639 0.0526315789473684 1.13805104408353 0.593474224651446 0.845323393613305 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/862 19/18639 0.0526315789473684 1.13805104408353 0.593474224651446 0.845323393613305 GO:0016918 retinal binding 1/862 19/18639 0.0526315789473684 1.13805104408353 0.593474224651446 0.845323393613305 GO:0043395 heparan sulfate proteoglycan binding 1/862 19/18639 0.0526315789473684 1.13805104408353 0.593474224651446 0.845323393613305 GO:0099589 serotonin receptor activity 1/862 19/18639 0.0526315789473684 1.13805104408353 0.593474224651446 0.845323393613305 GO:0141147 intracellularly calcium-gated channel activity 1/862 19/18639 0.0526315789473684 1.13805104408353 0.593474224651446 0.845323393613305 GO:0043022 ribosome binding 5/862 112/18639 0.0446428571428571 0.965311153463706 0.595766789495508 0.847454363667407 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/862 43/18639 0.0465116279069767 1.00571952732963 0.597581790217786 0.848074286481834 GO:0015297 antiporter activity 6/862 135/18639 0.0444444444444444 0.961020881670534 0.597796724493774 0.848074286481834 GO:0042054 histone methyltransferase activity 3/862 67/18639 0.0447761194029851 0.968192679294941 0.604583769566095 0.852723656047897 GO:0001223 transcription coactivator binding 2/862 44/18639 0.0454545454545455 0.982862265344864 0.610184051412184 0.852723656047897 GO:0001614 purinergic nucleotide receptor activity 1/862 20/18639 0.05 1.08114849187935 0.612294053778753 0.852723656047897 GO:0001972 retinoic acid binding 1/862 20/18639 0.05 1.08114849187935 0.612294053778753 0.852723656047897 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/862 20/18639 0.05 1.08114849187935 0.612294053778753 0.852723656047897 GO:0010851 cyclase regulator activity 1/862 20/18639 0.05 1.08114849187935 0.612294053778753 0.852723656047897 GO:0015095 magnesium ion transmembrane transporter activity 1/862 20/18639 0.05 1.08114849187935 0.612294053778753 0.852723656047897 GO:0016004 phospholipase activator activity 1/862 20/18639 0.05 1.08114849187935 0.612294053778753 0.852723656047897 GO:0016408 C-acyltransferase activity 1/862 20/18639 0.05 1.08114849187935 0.612294053778753 0.852723656047897 GO:0016502 nucleotide receptor activity 1/862 20/18639 0.05 1.08114849187935 0.612294053778753 0.852723656047897 GO:0016505 peptidase activator activity involved in apoptotic process 1/862 20/18639 0.05 1.08114849187935 0.612294053778753 0.852723656047897 GO:0030627 pre-mRNA 5'-splice site binding 1/862 20/18639 0.05 1.08114849187935 0.612294053778753 0.852723656047897 GO:0031418 L-ascorbic acid binding 1/862 20/18639 0.05 1.08114849187935 0.612294053778753 0.852723656047897 GO:0140939 histone H4 methyltransferase activity 1/862 20/18639 0.05 1.08114849187935 0.612294053778753 0.852723656047897 GO:0015079 potassium ion transmembrane transporter activity 7/862 160/18639 0.04375 0.946004930394431 0.613441086706618 0.853204334974956 GO:0001221 transcription coregulator binding 5/862 115/18639 0.0434782608695652 0.940129123373348 0.619267087998078 0.854583482151659 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/862 45/18639 0.0444444444444444 0.961020881670534 0.622482992113218 0.854583482151659 GO:0008009 chemokine activity 2/862 45/18639 0.0444444444444444 0.961020881670534 0.622482992113218 0.854583482151659 GO:0140303 intramembrane lipid transporter activity 2/862 45/18639 0.0444444444444444 0.961020881670534 0.622482992113218 0.854583482151659 GO:0016279 protein-lysine N-methyltransferase activity 3/862 69/18639 0.0434782608695652 0.940129123373348 0.624590323026205 0.854583482151659 GO:0015294 solute:monoatomic cation symporter activity 5/862 116/18639 0.0431034482758621 0.932024561964957 0.626918194314831 0.854583482151659 GO:0051213 dioxygenase activity 4/862 93/18639 0.043010752688172 0.930020208068258 0.629145098509242 0.854583482151659 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/862 21/18639 0.0476190476190476 1.02966523036129 0.630243595947651 0.854583482151659 GO:0009975 cyclase activity 1/862 21/18639 0.0476190476190476 1.02966523036129 0.630243595947651 0.854583482151659 GO:0015125 bile acid transmembrane transporter activity 1/862 21/18639 0.0476190476190476 1.02966523036129 0.630243595947651 0.854583482151659 GO:0015174 basic amino acid transmembrane transporter activity 1/862 21/18639 0.0476190476190476 1.02966523036129 0.630243595947651 0.854583482151659 GO:0072542 protein phosphatase activator activity 1/862 21/18639 0.0476190476190476 1.02966523036129 0.630243595947651 0.854583482151659 GO:0015276 ligand-gated monoatomic ion channel activity 8/862 186/18639 0.043010752688172 0.930020208068258 0.633327479750892 0.854583482151659 GO:0016278 lysine N-methyltransferase activity 3/862 70/18639 0.0428571428571429 0.926698707325157 0.634329668237056 0.854583482151659 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/862 46/18639 0.0434782608695652 0.940129123373348 0.634479681719403 0.854583482151659 GO:0030291 protein serine/threonine kinase inhibitor activity 2/862 46/18639 0.0434782608695652 0.940129123373348 0.634479681719403 0.854583482151659 GO:0042562 hormone binding 4/862 94/18639 0.0425531914893617 0.920126376067532 0.63753408255951 0.854583482151659 GO:0022834 ligand-gated channel activity 8/862 188/18639 0.0425531914893617 0.920126376067532 0.645217751564044 0.854583482151659 GO:0005125 cytokine activity 10/862 234/18639 0.0427350427350427 0.924058540067821 0.645975479751928 0.854583482151659 GO:0008970 phospholipase A1 activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0031683 G-protein beta/gamma-subunit complex binding 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0032931 histone H3K56 acetyltransferase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0033691 sialic acid binding 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0034062 5'-3' RNA polymerase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0043992 histone H3K9 acetyltransferase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0043993 histone H3K18 acetyltransferase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0043994 histone H3K23 acetyltransferase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0043999 histone H2AK5 acetyltransferase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0044012 histone H2AK9 acetyltransferase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0044014 histone H2BK5 acetyltransferase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0044015 histone H2BK12 acetyltransferase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0044016 histone H3K4 acetyltransferase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0044017 histone H3K27 acetyltransferase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0044018 histone H3K36 acetyltransferase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0046972 histone H4K16 acetyltransferase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0050321 tau-protein kinase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0070034 telomerase RNA binding 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0097747 RNA polymerase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0140517 protein-RNA adaptor activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0140908 histone H3K122 acetyltransferase activity 1/862 22/18639 0.0454545454545455 0.982862265344864 0.64736305132917 0.854583482151659 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/862 48/18639 0.0416666666666667 0.900957076566125 0.657573278911965 0.860687915471853 GO:0030594 neurotransmitter receptor activity 4/862 97/18639 0.0412371134020619 0.891668859281938 0.661951034011333 0.860687915471853 GO:0004521 RNA endonuclease activity 3/862 73/18639 0.0410958904109589 0.888615198804945 0.662481194399956 0.860687915471853 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/862 73/18639 0.0410958904109589 0.888615198804945 0.662481194399956 0.860687915471853 GO:0003887 DNA-directed DNA polymerase activity 1/862 23/18639 0.0434782608695652 0.940129123373348 0.663690765233358 0.860687915471853 GO:0005212 structural constituent of eye lens 1/862 23/18639 0.0434782608695652 0.940129123373348 0.663690765233358 0.860687915471853 GO:0005283 amino acid:sodium symporter activity 1/862 23/18639 0.0434782608695652 0.940129123373348 0.663690765233358 0.860687915471853 GO:0008171 O-methyltransferase activity 1/862 23/18639 0.0434782608695652 0.940129123373348 0.663690765233358 0.860687915471853 GO:0016493 C-C chemokine receptor activity 1/862 23/18639 0.0434782608695652 0.940129123373348 0.663690765233358 0.860687915471853 GO:0016849 phosphorus-oxygen lyase activity 1/862 23/18639 0.0434782608695652 0.940129123373348 0.663690765233358 0.860687915471853 GO:0043274 phospholipase binding 1/862 23/18639 0.0434782608695652 0.940129123373348 0.663690765233358 0.860687915471853 GO:0044013 histone H2B acetyltransferase activity 1/862 23/18639 0.0434782608695652 0.940129123373348 0.663690765233358 0.860687915471853 GO:0140103 catalytic activity, acting on a glycoprotein 1/862 23/18639 0.0434782608695652 0.940129123373348 0.663690765233358 0.860687915471853 GO:0051082 unfolded protein binding 5/862 121/18639 0.0413223140495868 0.893511150313513 0.663751499703171 0.860687915471853 GO:0005201 extracellular matrix structural constituent 7/862 168/18639 0.0416666666666667 0.900957076566125 0.664121032521045 0.860687915471853 GO:0001222 transcription corepressor binding 2/862 49/18639 0.0408163265306122 0.882570197452531 0.668674863736023 0.865535346733733 GO:0035064 methylated histone binding 3/862 74/18639 0.0405405405405405 0.876606885307581 0.671508132934235 0.865832812139227 GO:0004806 triacylglycerol lipase activity 1/862 24/18639 0.0416666666666667 0.900957076566125 0.67926331359868 0.865832812139227 GO:0015295 solute:proton symporter activity 1/862 24/18639 0.0416666666666667 0.900957076566125 0.67926331359868 0.865832812139227 GO:0019957 C-C chemokine binding 1/862 24/18639 0.0416666666666667 0.900957076566125 0.67926331359868 0.865832812139227 GO:0030552 cAMP binding 1/862 24/18639 0.0416666666666667 0.900957076566125 0.67926331359868 0.865832812139227 GO:0043998 histone H2A acetyltransferase activity 1/862 24/18639 0.0416666666666667 0.900957076566125 0.67926331359868 0.865832812139227 GO:0050431 transforming growth factor beta binding 1/862 24/18639 0.0416666666666667 0.900957076566125 0.67926331359868 0.865832812139227 GO:0060229 lipase activator activity 1/862 24/18639 0.0416666666666667 0.900957076566125 0.67926331359868 0.865832812139227 GO:0070300 phosphatidic acid binding 1/862 24/18639 0.0416666666666667 0.900957076566125 0.67926331359868 0.865832812139227 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/862 24/18639 0.0416666666666667 0.900957076566125 0.67926331359868 0.865832812139227 GO:0070840 dynein complex binding 1/862 24/18639 0.0416666666666667 0.900957076566125 0.67926331359868 0.865832812139227 GO:0032813 tumor necrosis factor receptor superfamily binding 2/862 50/18639 0.04 0.86491879350348 0.679483456894976 0.865832812139227 GO:0048020 CCR chemokine receptor binding 2/862 50/18639 0.04 0.86491879350348 0.679483456894976 0.865832812139227 GO:0005216 monoatomic ion channel activity 19/862 448/18639 0.0424107142857143 0.91704559579052 0.68448422560286 0.866829791028846 GO:0140034 methylation-dependent protein binding 3/862 76/18639 0.0394736842105263 0.853538283062645 0.689026719983662 0.866829791028846 GO:0005048 signal sequence binding 2/862 51/18639 0.0392156862745098 0.847959601474 0.690002380644872 0.866829791028846 GO:0016597 amino acid binding 2/862 51/18639 0.0392156862745098 0.847959601474 0.690002380644872 0.866829791028846 GO:0016830 carbon-carbon lyase activity 2/862 51/18639 0.0392156862745098 0.847959601474 0.690002380644872 0.866829791028846 GO:0005251 delayed rectifier potassium channel activity 1/862 25/18639 0.04 0.86491879350348 0.694115584545655 0.866829791028846 GO:0008139 nuclear localization sequence binding 1/862 25/18639 0.04 0.86491879350348 0.694115584545655 0.866829791028846 GO:0015271 outward rectifier potassium channel activity 1/862 25/18639 0.04 0.86491879350348 0.694115584545655 0.866829791028846 GO:0015645 fatty acid ligase activity 1/862 25/18639 0.04 0.86491879350348 0.694115584545655 0.866829791028846 GO:0017025 TBP-class protein binding 1/862 25/18639 0.04 0.86491879350348 0.694115584545655 0.866829791028846 GO:0017056 structural constituent of nuclear pore 1/862 25/18639 0.04 0.86491879350348 0.694115584545655 0.866829791028846 GO:0019211 phosphatase activator activity 1/862 25/18639 0.04 0.86491879350348 0.694115584545655 0.866829791028846 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/862 25/18639 0.04 0.86491879350348 0.694115584545655 0.866829791028846 GO:0019707 protein-cysteine S-acyltransferase activity 1/862 25/18639 0.04 0.86491879350348 0.694115584545655 0.866829791028846 GO:0047617 fatty acyl-CoA hydrolase activity 1/862 25/18639 0.04 0.86491879350348 0.694115584545655 0.866829791028846 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/862 25/18639 0.04 0.86491879350348 0.694115584545655 0.866829791028846 GO:0120515 fatty acid-CoA ligase activity 1/862 25/18639 0.04 0.86491879350348 0.694115584545655 0.866829791028846 GO:0030159 signaling receptor complex adaptor activity 2/862 52/18639 0.0384615384615385 0.831652686061039 0.7002352765908 0.867075510510921 GO:0042826 histone deacetylase binding 5/862 127/18639 0.0393700787401575 0.851298025101851 0.704715098148711 0.867075510510921 GO:0004722 protein serine/threonine phosphatase activity 4/862 103/18639 0.0388349514563107 0.839726983983961 0.707350787380092 0.867075510510921 GO:0005112 Notch binding 1/862 26/18639 0.0384615384615385 0.831652686061039 0.7082808561757 0.867075510510921 GO:0005227 calcium-activated cation channel activity 1/862 26/18639 0.0384615384615385 0.831652686061039 0.7082808561757 0.867075510510921 GO:0008066 glutamate receptor activity 1/862 26/18639 0.0384615384615385 0.831652686061039 0.7082808561757 0.867075510510921 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/862 26/18639 0.0384615384615385 0.831652686061039 0.7082808561757 0.867075510510921 GO:0008143 poly(A) binding 1/862 26/18639 0.0384615384615385 0.831652686061039 0.7082808561757 0.867075510510921 GO:0008157 protein phosphatase 1 binding 1/862 26/18639 0.0384615384615385 0.831652686061039 0.7082808561757 0.867075510510921 GO:0016289 acyl-CoA hydrolase activity 1/862 26/18639 0.0384615384615385 0.831652686061039 0.7082808561757 0.867075510510921 GO:0030507 spectrin binding 1/862 26/18639 0.0384615384615385 0.831652686061039 0.7082808561757 0.867075510510921 GO:0034237 protein kinase A regulatory subunit binding 1/862 26/18639 0.0384615384615385 0.831652686061039 0.7082808561757 0.867075510510921 GO:0050681 nuclear androgen receptor binding 1/862 26/18639 0.0384615384615385 0.831652686061039 0.7082808561757 0.867075510510921 GO:0097602 cullin family protein binding 1/862 26/18639 0.0384615384615385 0.831652686061039 0.7082808561757 0.867075510510921 GO:0004864 protein phosphatase inhibitor activity 2/862 53/18639 0.0377358490566038 0.815961125946679 0.710186069116612 0.867075510510921 GO:0005246 calcium channel regulator activity 2/862 53/18639 0.0377358490566038 0.815961125946679 0.710186069116612 0.867075510510921 GO:0017046 peptide hormone binding 2/862 53/18639 0.0377358490566038 0.815961125946679 0.710186069116612 0.867075510510921 GO:0140296 general transcription initiation factor binding 2/862 53/18639 0.0377358490566038 0.815961125946679 0.710186069116612 0.867075510510921 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/862 53/18639 0.0377358490566038 0.815961125946679 0.710186069116612 0.867075510510921 GO:0042393 histone binding 10/862 247/18639 0.0404858299595142 0.875423880064251 0.710935127349992 0.867075510510921 GO:0035591 signaling adaptor activity 5/862 129/18639 0.0387596899224806 0.838099606108024 0.717568639423938 0.867075510510921 GO:0003925 G protein activity 2/862 54/18639 0.037037037037037 0.800850734725445 0.719858931507415 0.867075510510921 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/862 27/18639 0.037037037037037 0.800850734725445 0.721790870787882 0.867075510510921 GO:0005385 zinc ion transmembrane transporter activity 1/862 27/18639 0.037037037037037 0.800850734725445 0.721790870787882 0.867075510510921 GO:0008266 poly(U) RNA binding 1/862 27/18639 0.037037037037037 0.800850734725445 0.721790870787882 0.867075510510921 GO:0008320 protein transmembrane transporter activity 1/862 27/18639 0.037037037037037 0.800850734725445 0.721790870787882 0.867075510510921 GO:0008395 steroid hydroxylase activity 1/862 27/18639 0.037037037037037 0.800850734725445 0.721790870787882 0.867075510510921 GO:0016405 CoA-ligase activity 1/862 27/18639 0.037037037037037 0.800850734725445 0.721790870787882 0.867075510510921 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/862 27/18639 0.037037037037037 0.800850734725445 0.721790870787882 0.867075510510921 GO:0004497 monooxygenase activity 4/862 106/18639 0.0377358490566038 0.815961125946679 0.728322523868976 0.867075510510921 GO:0008013 beta-catenin binding 4/862 106/18639 0.0377358490566038 0.815961125946679 0.728322523868976 0.867075510510921 GO:0015101 organic cation transmembrane transporter activity 3/862 81/18639 0.037037037037037 0.800850734725445 0.729728454474938 0.867075510510921 GO:0033192 calmodulin-dependent protein phosphatase activity 3/862 81/18639 0.037037037037037 0.800850734725445 0.729728454474938 0.867075510510921 GO:0140791 histone H2AXS140 phosphatase activity 3/862 81/18639 0.037037037037037 0.800850734725445 0.729728454474938 0.867075510510921 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 3/862 81/18639 0.037037037037037 0.800850734725445 0.729728454474938 0.867075510510921 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 3/862 81/18639 0.037037037037037 0.800850734725445 0.729728454474938 0.867075510510921 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 3/862 81/18639 0.037037037037037 0.800850734725445 0.729728454474938 0.867075510510921 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 3/862 81/18639 0.037037037037037 0.800850734725445 0.729728454474938 0.867075510510921 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 3/862 81/18639 0.037037037037037 0.800850734725445 0.729728454474938 0.867075510510921 GO:1990439 MAP kinase serine/threonine phosphatase activity 3/862 81/18639 0.037037037037037 0.800850734725445 0.729728454474938 0.867075510510921 GO:0031072 heat shock protein binding 5/862 131/18639 0.0381679389312977 0.825304192274313 0.730019750580905 0.867075510510921 GO:0008168 methyltransferase activity 8/862 204/18639 0.0392156862745098 0.847959601474 0.731969229386898 0.867075510510921 GO:0005242 inward rectifier potassium channel activity 1/862 28/18639 0.0357142857142857 0.772248922770965 0.734675905678321 0.867075510510921 GO:0016866 intramolecular transferase activity 1/862 28/18639 0.0357142857142857 0.772248922770965 0.734675905678321 0.867075510510921 GO:0019789 SUMO transferase activity 1/862 28/18639 0.0357142857142857 0.772248922770965 0.734675905678321 0.867075510510921 GO:0036408 histone H3K14 acetyltransferase activity 1/862 28/18639 0.0357142857142857 0.772248922770965 0.734675905678321 0.867075510510921 GO:0046966 nuclear thyroid hormone receptor binding 1/862 28/18639 0.0357142857142857 0.772248922770965 0.734675905678321 0.867075510510921 GO:0051393 alpha-actinin binding 1/862 28/18639 0.0357142857142857 0.772248922770965 0.734675905678321 0.867075510510921 GO:0051959 dynein light intermediate chain binding 1/862 28/18639 0.0357142857142857 0.772248922770965 0.734675905678321 0.867075510510921 GO:0019888 protein phosphatase regulator activity 4/862 107/18639 0.0373831775700935 0.80833532103129 0.735058374512077 0.867075510510921 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 3/862 82/18639 0.0365853658536585 0.791084262350744 0.737346304159181 0.867158376709479 GO:0033549 MAP kinase phosphatase activity 3/862 82/18639 0.0365853658536585 0.791084262350744 0.737346304159181 0.867158376709479 GO:0019212 phosphatase inhibitor activity 2/862 56/18639 0.0357142857142857 0.772248922770965 0.738388617762019 0.867158376709479 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/862 56/18639 0.0357142857142857 0.772248922770965 0.738388617762019 0.867158376709479 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 3/862 83/18639 0.036144578313253 0.781553126659771 0.744793155552431 0.870504480266038 GO:0004181 metallocarboxypeptidase activity 1/862 29/18639 0.0344827586206897 0.745619649571966 0.74696484067941 0.870504480266038 GO:0005416 amino acid:monoatomic cation symporter activity 1/862 29/18639 0.0344827586206897 0.745619649571966 0.74696484067941 0.870504480266038 GO:0010484 histone H3 acetyltransferase activity 1/862 29/18639 0.0344827586206897 0.745619649571966 0.74696484067941 0.870504480266038 GO:0016417 S-acyltransferase activity 1/862 29/18639 0.0344827586206897 0.745619649571966 0.74696484067941 0.870504480266038 GO:0043236 laminin binding 1/862 29/18639 0.0344827586206897 0.745619649571966 0.74696484067941 0.870504480266038 GO:0099604 ligand-gated calcium channel activity 1/862 29/18639 0.0344827586206897 0.745619649571966 0.74696484067941 0.870504480266038 GO:0004527 exonuclease activity 3/862 84/18639 0.0357142857142857 0.772248922770965 0.752070636009204 0.872693056037317 GO:0004860 protein kinase inhibitor activity 3/862 84/18639 0.0357142857142857 0.772248922770965 0.752070636009204 0.872693056037317 GO:0017018 myosin phosphatase activity 3/862 84/18639 0.0357142857142857 0.772248922770965 0.752070636009204 0.872693056037317 GO:0004518 nuclease activity 8/862 209/18639 0.0382775119617225 0.827673486606201 0.755883625256426 0.872693056037317 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/862 30/18639 0.0333333333333333 0.7207656612529 0.758685222588833 0.872693056037317 GO:0008187 poly-pyrimidine tract binding 1/862 30/18639 0.0333333333333333 0.7207656612529 0.758685222588833 0.872693056037317 GO:0022839 monoatomic ion-gated channel activity 1/862 30/18639 0.0333333333333333 0.7207656612529 0.758685222588833 0.872693056037317 GO:0033612 receptor serine/threonine kinase binding 1/862 30/18639 0.0333333333333333 0.7207656612529 0.758685222588833 0.872693056037317 GO:0043995 histone H4K5 acetyltransferase activity 1/862 30/18639 0.0333333333333333 0.7207656612529 0.758685222588833 0.872693056037317 GO:0043996 histone H4K8 acetyltransferase activity 1/862 30/18639 0.0333333333333333 0.7207656612529 0.758685222588833 0.872693056037317 GO:0043997 histone H4K12 acetyltransferase activity 1/862 30/18639 0.0333333333333333 0.7207656612529 0.758685222588833 0.872693056037317 GO:0051721 protein phosphatase 2A binding 1/862 30/18639 0.0333333333333333 0.7207656612529 0.758685222588833 0.872693056037317 GO:0016922 nuclear receptor binding 5/862 137/18639 0.0364963503649635 0.789159483123613 0.76497089516562 0.878973037209741 GO:0046873 metal ion transmembrane transporter activity 18/862 450/18639 0.04 0.86491879350348 0.769809574680848 0.880789870468631 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/862 31/18639 0.032258064516129 0.697515156051194 0.769863326631416 0.880789870468631 GO:0005452 solute:inorganic anion antiporter activity 1/862 31/18639 0.032258064516129 0.697515156051194 0.769863326631416 0.880789870468631 GO:0016878 acid-thiol ligase activity 1/862 31/18639 0.032258064516129 0.697515156051194 0.769863326631416 0.880789870468631 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/862 60/18639 0.0333333333333333 0.7207656612529 0.772317215344053 0.881701198633125 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/862 60/18639 0.0333333333333333 0.7207656612529 0.772317215344053 0.881701198633125 GO:0140996 histone H3 kinase activity 14/862 357/18639 0.0392156862745098 0.847959601474 0.773604793310314 0.882224544568246 GO:0140767 enzyme-substrate adaptor activity 5/862 139/18639 0.0359712230215827 0.777804670416799 0.775829840309729 0.883814721723289 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/862 61/18639 0.0327868852459016 0.708949830740558 0.780176306458549 0.884427864596512 GO:0030515 snoRNA binding 1/862 32/18639 0.03125 0.675717807424594 0.780524215090343 0.884427864596512 GO:0051059 NF-kappaB binding 1/862 32/18639 0.03125 0.675717807424594 0.780524215090343 0.884427864596512 GO:0070717 poly-purine tract binding 1/862 32/18639 0.03125 0.675717807424594 0.780524215090343 0.884427864596512 GO:0140142 nucleocytoplasmic carrier activity 1/862 32/18639 0.03125 0.675717807424594 0.780524215090343 0.884427864596512 GO:0035173 histone kinase activity 14/862 360/18639 0.0388888888888889 0.840893271461717 0.783741579877293 0.887128767010043 GO:0071889 14-3-3 protein binding 1/862 33/18639 0.0303030303030303 0.655241510229909 0.790691793237929 0.893095613593584 GO:0140416 transcription regulator inhibitor activity 1/862 33/18639 0.0303030303030303 0.655241510229909 0.790691793237929 0.893095613593584 GO:0019210 kinase inhibitor activity 3/862 90/18639 0.0333333333333333 0.7207656612529 0.792283338594578 0.893944297205335 GO:0019208 phosphatase regulator activity 4/862 117/18639 0.0341880341880342 0.739246832054257 0.795586801508511 0.896435526213021 GO:0005261 monoatomic cation channel activity 13/862 341/18639 0.0381231671554252 0.824336093515047 0.799904936862114 0.896435526213021 GO:0008175 tRNA methyltransferase activity 1/862 34/18639 0.0294117647058824 0.6359697011055 0.800388862690197 0.896435526213021 GO:0015020 glucuronosyltransferase activity 1/862 34/18639 0.0294117647058824 0.6359697011055 0.800388862690197 0.896435526213021 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/862 34/18639 0.0294117647058824 0.6359697011055 0.800388862690197 0.896435526213021 GO:0030332 cyclin binding 1/862 34/18639 0.0294117647058824 0.6359697011055 0.800388862690197 0.896435526213021 GO:0051427 hormone receptor binding 1/862 34/18639 0.0294117647058824 0.6359697011055 0.800388862690197 0.896435526213021 GO:0004536 DNA nuclease activity 2/862 64/18639 0.03125 0.675717807424594 0.802341312700717 0.897677346701959 GO:0022836 gated channel activity 12/862 318/18639 0.0377358490566038 0.815961125946679 0.803564054622023 0.898101002224614 GO:0160215 deacylase activity 2/862 65/18639 0.0307692307692308 0.665322148848831 0.809276484017378 0.901102459551507 GO:0005343 organic acid:sodium symporter activity 1/862 35/18639 0.0285714285714286 0.617799138216772 0.809637172303798 0.901102459551507 GO:0010485 histone H4 acetyltransferase activity 1/862 35/18639 0.0285714285714286 0.617799138216772 0.809637172303798 0.901102459551507 GO:0034061 DNA polymerase activity 1/862 35/18639 0.0285714285714286 0.617799138216772 0.809637172303798 0.901102459551507 GO:0015293 symporter activity 5/862 146/18639 0.0342465753424658 0.740512665670788 0.810810987330975 0.901465925308419 GO:0015085 calcium ion transmembrane transporter activity 5/862 147/18639 0.0340136054421769 0.735475164543776 0.815434253080909 0.905659754987565 GO:0004540 RNA nuclease activity 4/862 121/18639 0.0330578512396694 0.71480892025081 0.816463015389046 0.905856776198065 GO:0016409 palmitoyltransferase activity 1/862 36/18639 0.0277777777777778 0.600638051044084 0.818457466728337 0.906179755045734 GO:0045505 dynein intermediate chain binding 1/862 36/18639 0.0277777777777778 0.600638051044084 0.818457466728337 0.906179755045734 GO:0008276 protein methyltransferase activity 3/862 95/18639 0.0315789473684211 0.682830626450116 0.82150827258465 0.908612060322316 GO:0019213 deacetylase activity 1/862 37/18639 0.027027027027027 0.584404590205054 0.826869532722004 0.909813012219454 GO:0022829 wide pore channel activity 1/862 37/18639 0.027027027027027 0.584404590205054 0.826869532722004 0.909813012219454 GO:0030280 structural constituent of skin epidermis 1/862 37/18639 0.027027027027027 0.584404590205054 0.826869532722004 0.909813012219454 GO:0030551 cyclic nucleotide binding 1/862 37/18639 0.027027027027027 0.584404590205054 0.826869532722004 0.909813012219454 GO:0042805 actinin binding 1/862 37/18639 0.027027027027027 0.584404590205054 0.826869532722004 0.909813012219454 GO:0098960 postsynaptic neurotransmitter receptor activity 2/862 69/18639 0.0289855072463768 0.626752748915565 0.834892230660523 0.915799326708003 GO:0005109 frizzled binding 1/862 38/18639 0.0263157894736842 0.569025522041763 0.834892243333423 0.915799326708003 GO:0042162 telomeric DNA binding 1/862 38/18639 0.0263157894736842 0.569025522041763 0.834892243333423 0.915799326708003 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 8/862 229/18639 0.0349344978165939 0.755387592579459 0.836288768295331 0.916386456710847 GO:0141003 histone H2AX kinase activity 13/862 354/18639 0.0367231638418079 0.794063864092178 0.838993747878648 0.91840467874782 GO:0004519 endonuclease activity 4/862 127/18639 0.031496062992126 0.681038420081481 0.844462836728553 0.923441375415396 GO:0140299 molecular sensor activity 2/862 71/18639 0.028169014084507 0.609097741903859 0.846498360195279 0.924716894504904 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 6/862 181/18639 0.0331491712707182 0.716783530527746 0.847982561682922 0.925289601921353 GO:0031490 chromatin DNA binding 4/862 128/18639 0.03125 0.675717807424594 0.848761890484249 0.925289601921353 GO:0071855 neuropeptide receptor binding 1/862 40/18639 0.025 0.540574245939675 0.849840772991948 0.92551748460945 GO:0042379 chemokine receptor binding 2/862 72/18639 0.0277777777777778 0.600638051044084 0.852019008970612 0.926940925914858 GO:0008227 G protein-coupled amine receptor activity 1/862 41/18639 0.024390243902439 0.527389508233829 0.85680013928481 0.929361341083262 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/862 41/18639 0.024390243902439 0.527389508233829 0.85680013928481 0.929361341083262 GO:0140097 catalytic activity, acting on DNA 12/862 336/18639 0.0357142857142857 0.772248922770965 0.856864168799511 0.929361341083262 GO:0005262 calcium channel activity 4/862 131/18639 0.0305343511450382 0.660243353819451 0.861060217850007 0.930797677891858 GO:0003678 DNA helicase activity 2/862 74/18639 0.027027027027027 0.584404590205054 0.862520601488926 0.930797677891858 GO:0003684 damaged DNA binding 2/862 74/18639 0.027027027027027 0.584404590205054 0.862520601488926 0.930797677891858 GO:0004402 histone acetyltransferase activity 1/862 42/18639 0.0238095238095238 0.514832615180643 0.863437319623368 0.930797677891858 GO:0008307 structural constituent of muscle 1/862 42/18639 0.0238095238095238 0.514832615180643 0.863437319623368 0.930797677891858 GO:0048487 beta-tubulin binding 1/862 42/18639 0.0238095238095238 0.514832615180643 0.863437319623368 0.930797677891858 GO:0044183 protein folding chaperone 2/862 75/18639 0.0266666666666667 0.57661252900232 0.867511397626541 0.934243043597813 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/862 43/18639 0.0232558139534884 0.502859763664814 0.869767213180643 0.935725293047729 GO:0001046 core promoter sequence-specific DNA binding 1/862 44/18639 0.0227272727272727 0.491431132672432 0.875804030896189 0.941268170579338 GO:0061659 ubiquitin-like protein ligase activity 13/862 372/18639 0.0349462365591398 0.75564141905546 0.883160032823944 0.947859493384825 GO:0016755 aminoacyltransferase activity 18/862 496/18639 0.0362903225806452 0.784704550557593 0.883718625411416 0.947859493384825 GO:0015370 solute:sodium symporter activity 2/862 79/18639 0.0253164556962025 0.547416957913595 0.885852709435084 0.949191624208388 GO:0000049 tRNA binding 2/862 80/18639 0.025 0.540574245939675 0.890055647997409 0.950345279045994 GO:0043495 protein-membrane adaptor activity 1/862 47/18639 0.0212765957446809 0.460063188033766 0.892288471585478 0.950345279045994 GO:0061733 protein-lysine-acetyltransferase activity 1/862 47/18639 0.0212765957446809 0.460063188033766 0.892288471585478 0.950345279045994 GO:0061749 forked DNA-dependent helicase activity 1/862 47/18639 0.0212765957446809 0.460063188033766 0.892288471585478 0.950345279045994 GO:0140938 histone H3 methyltransferase activity 1/862 47/18639 0.0212765957446809 0.460063188033766 0.892288471585478 0.950345279045994 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/862 47/18639 0.0212765957446809 0.460063188033766 0.892288471585478 0.950345279045994 GO:0009378 four-way junction helicase activity 1/862 48/18639 0.0208333333333333 0.450478538283063 0.897282411855127 0.952092712930518 GO:0036121 double-stranded DNA helicase activity 1/862 48/18639 0.0208333333333333 0.450478538283063 0.897282411855127 0.952092712930518 GO:0043138 3'-5' DNA helicase activity 1/862 48/18639 0.0208333333333333 0.450478538283063 0.897282411855127 0.952092712930518 GO:0019787 ubiquitin-like protein transferase activity 17/862 479/18639 0.0354906054279749 0.767412290686804 0.897508450253111 0.952092712930518 GO:0030544 Hsp70 protein binding 1/862 51/18639 0.0196078431372549 0.423979800737 0.910918838069861 0.964999952273192 GO:0022832 voltage-gated channel activity 5/862 175/18639 0.0285714285714286 0.617799138216772 0.911818994544205 0.964999952273192 GO:0050660 flavin adenine dinucleotide binding 2/862 86/18639 0.0232558139534884 0.502859763664814 0.912396571416195 0.964999952273192 GO:0034212 protein N-acetyltransferase activity 1/862 53/18639 0.0188679245283019 0.40798056297334 0.918989577125293 0.971007855075781 GO:0003697 single-stranded DNA binding 3/862 121/18639 0.0247933884297521 0.536106690188108 0.922888909393211 0.974160515470612 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/862 122/18639 0.0245901639344262 0.531712373055418 0.925447457735754 0.975893057513223 GO:0005267 potassium channel activity 3/862 124/18639 0.0241935483870968 0.523136367038395 0.930332523017197 0.98007307375277 GO:0016410 N-acyltransferase activity 2/862 94/18639 0.0212765957446809 0.460063188033766 0.935611956266044 0.982273023127868 GO:0008408 3'-5' exonuclease activity 1/862 58/18639 0.0172413793103448 0.372809824785983 0.93611357655231 0.982273023127868 GO:0017116 single-stranded DNA helicase activity 1/862 58/18639 0.0172413793103448 0.372809824785983 0.93611357655231 0.982273023127868 GO:0061980 regulatory RNA binding 1/862 58/18639 0.0172413793103448 0.372809824785983 0.93611357655231 0.982273023127868 GO:0019783 ubiquitin-like protein peptidase activity 3/862 127/18639 0.0236220472440945 0.51077881506111 0.937110197759329 0.98235000040978 GO:0015459 potassium channel regulator activity 1/862 59/18639 0.0169491525423729 0.36649101419639 0.939077361978924 0.982611627277995 GO:0061630 ubiquitin protein ligase activity 11/862 353/18639 0.0311614730878187 0.673803592672683 0.93920679035876 0.982611627277995 GO:0035402 histone H3T11 kinase activity 7/862 247/18639 0.0283400809716599 0.612796716044976 0.942592457759159 0.985185044259082 GO:0005249 voltage-gated potassium channel activity 2/862 98/18639 0.0204081632653061 0.441285098726265 0.94490565924242 0.98663358335028 GO:0140098 catalytic activity, acting on RNA 12/862 387/18639 0.0310077519379845 0.670479684886419 0.948386520490341 0.989297311570317 GO:0099094 ligand-gated monoatomic cation channel activity 3/862 136/18639 0.0220588235294118 0.476977275829125 0.953955037289261 0.994131400270102 GO:0004842 ubiquitin-protein transferase activity 14/862 449/18639 0.0311804008908686 0.674212867987123 0.957541665479654 0.995623831445576 GO:0008173 RNA methyltransferase activity 1/862 67/18639 0.0149253731343284 0.322730893098314 0.958341967727089 0.995623831445576 GO:0003777 microtubule motor activity 1/862 68/18639 0.0147058823529412 0.31798485055275 0.960275481824615 0.995623831445576 GO:0140223 general transcription initiation factor activity 1/862 68/18639 0.0147058823529412 0.31798485055275 0.960275481824615 0.995623831445576 GO:0005244 voltage-gated monoatomic ion channel activity 4/862 173/18639 0.023121387283237 0.499953059828601 0.961567637917226 0.995623831445576 GO:0002039 p53 binding 1/862 69/18639 0.0144927536231884 0.313376374457783 0.962119353165264 0.995623831445576 GO:0008080 N-acetyltransferase activity 1/862 69/18639 0.0144927536231884 0.313376374457783 0.962119353165264 0.995623831445576 GO:0004843 cysteine-type deubiquitinase activity 2/862 108/18639 0.0185185185185185 0.400425367362722 0.962873047516445 0.995623831445576 GO:0004674 protein serine/threonine kinase activity 13/862 433/18639 0.0300230946882217 0.649188470874437 0.966190462622761 0.995759918783298 GO:0031491 nucleosome binding 1/862 74/18639 0.0135135135135135 0.292202295102527 0.970132831796495 0.995759918783298 GO:0101005 deubiquitinase activity 2/862 115/18639 0.0173913043478261 0.376051649349339 0.971943111207352 0.995759918783298 GO:0017022 myosin binding 1/862 76/18639 0.0131578947368421 0.284512761020882 0.972842065268604 0.995759918783298 GO:0106310 protein serine kinase activity 9/862 361/18639 0.0249307479224377 0.539076810355355 0.987340157454169 0.995759918783298 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 5/862 243/18639 0.0205761316872428 0.444917074847469 0.988955268748804 0.995759918783298 GO:0140101 catalytic activity, acting on a tRNA 2/862 139/18639 0.0143884892086331 0.31112186816672 0.989471013297055 0.995759918783298 GO:0016407 acetyltransferase activity 1/862 96/18639 0.0104166666666667 0.225239269141531 0.989512478546109 0.995759918783298 GO:0004676 3-phosphoinositide-dependent protein kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0004711 ribosomal protein S6 kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0035175 histone H3S10 kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0035979 histone H2AXS139 kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0044022 histone H3S28 kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0044023 histone H4S1 kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0044024 histone H2AS1 kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0044025 histone H2BS14 kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0072354 histone H3T3 kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0072371 histone H2AS121 kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0072518 Rho-dependent protein serine/threonine kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0140823 histone H2BS36 kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0140855 histone H3S57 kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0140995 histone H2A kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0140997 histone H4 kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0140998 histone H2B kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:1990244 histone H2AT120 kinase activity 5/862 245/18639 0.0204081632653061 0.441285098726265 0.989658570664374 0.995759918783298 GO:0004677 DNA-dependent protein kinase activity 5/862 246/18639 0.0203252032520325 0.439491256861525 0.989994089280245 0.995759918783298 GO:0140857 histone H3T45 kinase activity 5/862 246/18639 0.0203252032520325 0.439491256861525 0.989994089280245 0.995759918783298 GO:0035403 histone H3T6 kinase activity 5/862 247/18639 0.0202429149797571 0.437711940032126 0.990319262168553 0.995759918783298 GO:0004679 AMP-activated protein kinase activity 5/862 248/18639 0.0201612903225806 0.435946972531996 0.990634386415035 0.995759918783298 GO:0022843 voltage-gated monoatomic cation channel activity 2/862 143/18639 0.013986013986014 0.30241915856765 0.991080595856685 0.995759918783298 GO:0008017 microtubule binding 5/862 276/18639 0.0181159420289855 0.391720468072228 0.996369647320981 0.999872714443972 GO:0003730 mRNA 3'-UTR binding 4/862 262/18639 0.0152671755725191 0.330121676909725 0.998321456347033 0.999872714443972 GO:0015631 tubulin binding 7/862 385/18639 0.0181818181818182 0.393144906137946 0.999100852125816 0.999872714443972 GO:0045182 translation regulator activity 6/862 356/18639 0.0168539325842697 0.364432075914388 0.999249507280661 0.999872714443972 GO:0030371 translation repressor activity 4/862 329/18639 0.0121580547112462 0.262893250305009 0.999872714443972 0.999872714443972