ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0042277	peptide binding	27/524	249/18639	0.108433734939759	3.857054170882	2.18434200196029e-09	1.9091149097133e-06
GO:0140375	immune receptor activity	20/524	156/18639	0.128205128205128	4.56033470346447	1.60724497945783e-08	7.02366056023071e-06
GO:0001540	amyloid-beta binding	14/524	83/18639	0.168674698795181	5.99986204359422	7.23377359408033e-08	2.10743937374207e-05
GO:0038024	cargo receptor activity	12/524	65/18639	0.184615384615385	6.56688197298884	2.23171946676005e-07	4.8763070348707e-05
GO:0140313	molecular sequestering activity	10/524	55/18639	0.181818181818182	6.46738376127689	2.6559762560987e-06	0.000402495020350447
GO:0140311	protein sequestering activity	8/524	33/18639	0.242424242424242	8.62317834836919	2.76312370949963e-06	0.000402495020350447
GO:0042605	peptide antigen binding	9/524	45/18639	0.2	7.11412213740458	3.68280042659692e-06	0.000459823938977959
GO:0030169	low-density lipoprotein particle binding	6/524	17/18639	0.352941176470588	12.5543331836551	4.56001232357596e-06	0.000498181346350674
GO:0032396	inhibitory MHC class I receptor activity	5/524	13/18639	0.384615384615385	13.6810041103934	1.83923267226674e-05	0.00164352925995546
GO:0042056	chemoattractant activity	8/524	42/18639	0.19047619047619	6.77535441657579	1.8804682608186e-05	0.00164352925995546
GO:0071813	lipoprotein particle binding	7/524	32/18639	0.21875	7.78107108778626	2.43655400321132e-05	0.00177462349900558
GO:0071814	protein-lipid complex binding	7/524	32/18639	0.21875	7.78107108778626	2.43655400321132e-05	0.00177462349900558
GO:0051015	actin filament binding	18/524	209/18639	0.0861244019138756	3.06349757113116	2.68556467057246e-05	0.00180552578621564
GO:0005126	cytokine receptor binding	21/524	275/18639	0.0763636363636364	2.71630117973629	3.60650524477133e-05	0.00225148970280725
GO:0005041	low-density lipoprotein particle receptor activity	5/524	15/18639	0.333333333333333	11.8568702290076	4.09570759626153e-05	0.00238643229275505
GO:0005539	glycosaminoglycan binding	19/524	242/18639	0.0785123966942149	2.79273389691502	5.79077298687232e-05	0.003163209744079
GO:0023023	MHC protein complex binding	7/524	37/18639	0.189189189189189	6.72957499484217	6.59927067269494e-05	0.00320431253774188
GO:0043394	proteoglycan binding	7/524	37/18639	0.189189189189189	6.72957499484217	6.59927067269494e-05	0.00320431253774188
GO:0046332	SMAD binding	10/524	79/18639	0.126582278481013	4.50260894772442	7.15801143054221e-05	0.00329268525804942
GO:0045296	cadherin binding	23/524	334/18639	0.0688622754491018	2.44947319102254	7.7646242427446e-05	0.00339314079407939
GO:0030228	lipoprotein particle receptor activity	5/524	18/18639	0.277777777777778	9.88072519083969	0.000108962677258654	0.00428318894523033
GO:0032393	MHC class I receptor activity	5/524	18/18639	0.277777777777778	9.88072519083969	0.000108962677258654	0.00428318894523033
GO:0031720	haptoglobin binding	4/524	10/18639	0.4	14.2282442748092	0.000113322608463993	0.00428318894523033
GO:0002020	protease binding	13/524	136/18639	0.0955882352941176	3.4001319039066	0.000122319965341046	0.00428318894523033
GO:0003823	antigen binding	15/524	174/18639	0.0862068965517241	3.06643195577784	0.000122516846259449	0.00428318894523033
GO:0001530	lipopolysaccharide binding	7/524	41/18639	0.170731707317073	6.07303109290635	0.000130766628929885	0.00439577052633535
GO:0097110	scaffold protein binding	9/524	70/18639	0.128571428571429	4.57336423118866	0.000145010081948816	0.00469403006012093
GO:0001968	fibronectin binding	6/524	30/18639	0.2	7.11412213740458	0.000160315911628711	0.00500414667012477
GO:0005178	integrin binding	14/524	161/18639	0.0869565217391304	3.09309658148025	0.000186697270693163	0.00562666946847671
GO:0019903	protein phosphatase binding	13/524	144/18639	0.0902777777777778	3.2112356870229	0.000217075127379749	0.00632412204433001
GO:0033218	amide binding	18/524	247/18639	0.0728744939271255	2.5921902524956	0.000229370063045215	0.00646675597101671
GO:0035259	nuclear glucocorticoid receptor binding	4/524	12/18639	0.333333333333333	11.8568702290076	0.000255394407423173	0.00697545975274541
GO:0140297	DNA-binding transcription factor binding	28/524	488/18639	0.0573770491803279	2.04093667876361	0.000309094375166312	0.0081863176937987
GO:0001618	virus receptor activity	9/524	81/18639	0.111111111111111	3.95229007633588	0.000442933532462633	0.0113859972756571
GO:0140272	exogenous protein binding	9/524	82/18639	0.109756097560976	3.90409141686837	0.000485386189453747	0.011989344273943
GO:0005344	oxygen carrier activity	4/524	14/18639	0.285714285714286	10.1630316248637	0.000493840267576601	0.011989344273943
GO:0120020	cholesterol transfer activity	5/524	25/18639	0.2	7.11412213740458	0.000574258819900335	0.0135649245565647
GO:0030695	GTPase regulator activity	27/524	489/18639	0.0552147239263804	1.96402144897672	0.000708115520983825	0.016286656982628
GO:0060589	nucleoside-triphosphatase regulator activity	27/524	490/18639	0.0551020408163265	1.960013241938	0.000730161035026265	0.0163630960157168
GO:0055102	lipase inhibitor activity	4/524	16/18639	0.25	8.89265267175572	0.000858633363227245	0.0187611389865153
GO:0005518	collagen binding	8/524	72/18639	0.111111111111111	3.95229007633588	0.000912845289007335	0.0194100257434139
GO:0001217	DNA-binding transcription repressor activity	18/524	278/18639	0.0647482014388489	2.30313306606623	0.000932747232521035	0.0194100257434139
GO:0035198	miRNA binding	6/524	42/18639	0.142857142857143	5.08151581243184	0.00106499324769707	0.0216466069415637
GO:0061980	regulatory RNA binding	7/524	58/18639	0.120689655172414	4.29300473808897	0.00115951297311332	0.022927708678885
GO:0008201	heparin binding	13/524	172/18639	0.0755813953488372	2.68847638913545	0.00118048843312337	0.022927708678885
GO:0005506	iron ion binding	12/524	154/18639	0.0779220779220779	2.7717358976901	0.00138855487051184	0.0263825425397249
GO:0004714	transmembrane receptor protein tyrosine kinase activity	7/524	60/18639	0.116666666666667	4.14990458015267	0.00141935516094161	0.0263939661843185
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	17/524	268/18639	0.0634328358208955	2.25634470775892	0.00159502004236606	0.0285131550835715
GO:0070325	lipoprotein particle receptor binding	5/524	31/18639	0.161290322580645	5.73719527210047	0.00159856361452518	0.0285131550835715
GO:0003779	actin binding	24/524	443/18639	0.054176072234763	1.92707597401478	0.00176918136235583	0.0309252902139799
GO:0120015	sterol transfer activity	5/524	32/18639	0.15625	5.55790791984733	0.00185139345733046	0.0317278016020946
GO:0042288	MHC class I protein binding	4/524	20/18639	0.2	7.11412213740458	0.0020908012932404	0.0350674946623127
GO:0140693	molecular condensate scaffold activity	6/524	48/18639	0.125	4.44632633587786	0.00216191355931234	0.0350674946623127
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	20/524	349/18639	0.0573065902578797	2.03843041186378	0.00218442691152473	0.0350674946623127
GO:0051082	unfolded protein binding	10/524	121/18639	0.0826446280991736	2.9397198914895	0.00220676453824622	0.0350674946623127
GO:0005125	cytokine activity	15/524	234/18639	0.0641025641025641	2.28016735173224	0.00265530122233322	0.0409482946043377
GO:0048020	CCR chemokine receptor binding	6/524	50/18639	0.12	4.26847328244275	0.00267054095245681	0.0409482946043377
GO:0019902	phosphatase binding	13/524	190/18639	0.068421052631579	2.4337786259542	0.00285946307193793	0.0423550906882836
GO:0016209	antioxidant activity	8/524	86/18639	0.0930232558139535	3.30889401739748	0.00287744769363484	0.0423550906882836
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	7/524	68/18639	0.102941176470588	3.66168051189942	0.00294006086172755	0.0423550906882836
GO:0005021	vascular endothelial growth factor receptor activity	6/524	51/18639	0.117647058823529	4.18477772788505	0.00295613333179096	0.0423550906882836
GO:0001851	complement component C3b binding	3/524	11/18639	0.272727272727273	9.70107564191534	0.00307985874344896	0.0427269292345142
GO:0042608	T cell receptor binding	3/524	11/18639	0.272727272727273	9.70107564191534	0.00307985874344896	0.0427269292345142
GO:0001216	DNA-binding transcription activator activity	25/524	491/18639	0.0509164969450102	1.81113089037795	0.00327264062593549	0.0446919985479315
GO:0005003	ephrin receptor activity	6/524	53/18639	0.113207547169811	4.02686158721014	0.00359501068319243	0.0470268956554835
GO:0005005	transmembrane-ephrin receptor activity	6/524	53/18639	0.113207547169811	4.02686158721014	0.00359501068319243	0.0470268956554835
GO:0004857	enzyme inhibitor activity	22/524	416/18639	0.0528846153846154	1.8811380651791	0.00360503662347528	0.0470268956554835
GO:0043531	ADP binding	5/524	38/18639	0.131578947368421	4.68034351145038	0.00401974488229234	0.0506855682285247
GO:0004859	phospholipase inhibitor activity	3/524	12/18639	0.25	8.89265267175572	0.00402134685545756	0.0506855682285247
GO:0042379	chemokine receptor binding	7/524	72/18639	0.0972222222222222	3.45825381679389	0.00405948486956148	0.0506855682285247
GO:0140104	molecular carrier activity	15/524	249/18639	0.0602409638554217	2.14280787271222	0.00474089316473254	0.0583597271264259
GO:0019838	growth factor binding	10/524	136/18639	0.0735294117647059	2.61548607992815	0.0051162391424308	0.0604658275820752
GO:0005172	vascular endothelial growth factor receptor binding	3/524	13/18639	0.230769230769231	8.20860246623605	0.00511953231244115	0.0604658275820752
GO:0017154	semaphorin receptor activity	3/524	13/18639	0.230769230769231	8.20860246623605	0.00511953231244115	0.0604658275820752
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	24/524	484/18639	0.0495867768595041	1.7638319348937	0.00541461429650386	0.060940107039001
GO:0009055	electron transfer activity	9/524	116/18639	0.0775862068965517	2.75978876020005	0.00547184732241751	0.060940107039001
GO:0042169	SH2 domain binding	5/524	41/18639	0.121951219512195	4.33787935207596	0.00560257954970145	0.060940107039001
GO:0004896	cytokine receptor activity	8/524	96/18639	0.0833333333333333	2.96421755725191	0.00564296838279849	0.060940107039001
GO:0008157	protein phosphatase 1 binding	4/524	26/18639	0.153846153846154	5.47240164415737	0.00564776735716142	0.060940107039001
GO:0050750	low-density lipoprotein particle receptor binding	4/524	26/18639	0.153846153846154	5.47240164415737	0.00564776735716142	0.060940107039001
GO:0070006	metalloaminopeptidase activity	4/524	26/18639	0.153846153846154	5.47240164415737	0.00564776735716142	0.060940107039001
GO:0008237	metallopeptidase activity	12/524	184/18639	0.0652173913043478	2.31982243611019	0.00596269440057104	0.0635535964158426
GO:0004713	protein tyrosine kinase activity	10/524	140/18639	0.0714285714285714	2.54075790621592	0.00625626757325956	0.0636851802557307
GO:0019199	transmembrane receptor protein kinase activity	7/524	78/18639	0.0897435897435897	3.19223429242513	0.00630828745838208	0.0636851802557307
GO:0005161	platelet-derived growth factor receptor binding	3/524	14/18639	0.214285714285714	7.62227371864776	0.00638108468831328	0.0636851802557307
GO:0019763	immunoglobulin receptor activity	3/524	14/18639	0.214285714285714	7.62227371864776	0.00638108468831328	0.0636851802557307
GO:0044548	S100 protein binding	3/524	14/18639	0.214285714285714	7.62227371864776	0.00638108468831328	0.0636851802557307
GO:0005044	scavenger receptor activity	4/524	27/18639	0.148148148148148	5.26972010178117	0.00648510416791766	0.0636851802557307
GO:0023026	MHC class II protein complex binding	4/524	27/18639	0.148148148148148	5.26972010178117	0.00648510416791766	0.0636851802557307
GO:0008186	ATP-dependent activity, acting on RNA	7/524	79/18639	0.0886075949367089	3.15182626340709	0.00675851119373364	0.0656326531480356
GO:0048156	tau protein binding	5/524	43/18639	0.116279069767442	4.13611752174685	0.0068745862635015	0.0660262460912123
GO:0030547	signaling receptor inhibitor activity	5/524	44/18639	0.113636363636364	4.04211485079806	0.00758070385666742	0.0720166866383405
GO:0008009	chemokine activity	5/524	45/18639	0.111111111111111	3.95229007633588	0.00833575412692685	0.0780807627002402
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	4/524	29/18639	0.137931034482759	4.90629112924454	0.00839770216684506	0.0780807627002402
GO:0017070	U6 snRNA binding	3/524	16/18639	0.1875	6.66948950381679	0.00941628410911351	0.0866298138038443
GO:0044389	ubiquitin-like protein ligase binding	17/524	322/18639	0.0527950310559006	1.87795149589872	0.00996410727334045	0.0885070135873951
GO:0000510	H3-H4 histone complex chaperone activity	10/524	151/18639	0.0662251655629139	2.35566958192205	0.0104217103105116	0.0885070135873951
GO:0140584	chromatin extrusion motor activity	10/524	151/18639	0.0662251655629139	2.35566958192205	0.0104217103105116	0.0885070135873951
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	10/524	151/18639	0.0662251655629139	2.35566958192205	0.0104217103105116	0.0885070135873951
GO:0140849	ATP-dependent H2AZ histone chaperone activity	10/524	151/18639	0.0662251655629139	2.35566958192205	0.0104217103105116	0.0885070135873951
GO:0015616	DNA translocase activity	10/524	152/18639	0.0657894736842105	2.34017175572519	0.0108851297891278	0.0885070135873951
GO:0140674	ATP-dependent histone chaperone activity	10/524	152/18639	0.0657894736842105	2.34017175572519	0.0108851297891278	0.0885070135873951
GO:0004175	endopeptidase activity	20/524	405/18639	0.0493827160493827	1.75657336726039	0.0110104775435303	0.0885070135873951
GO:1901681	sulfur compound binding	15/524	275/18639	0.0545454545454545	1.94021512838307	0.0113623531383171	0.0885070135873951
GO:0061775	cohesin loader activity	10/524	153/18639	0.065359477124183	2.32487651549169	0.0113640200090759	0.0885070135873951
GO:0031625	ubiquitin protein ligase binding	16/524	302/18639	0.0529801324503311	1.88453566553764	0.011818314944237	0.0885070135873951
GO:0061134	peptidase regulator activity	13/524	226/18639	0.0575221238938053	2.04609707491725	0.0118353542199403	0.0885070135873951
GO:0005004	GPI-linked ephrin receptor activity	5/524	49/18639	0.102040816326531	3.62965415173703	0.0118766855873285	0.0885070135873951
GO:0005008	hepatocyte growth factor receptor activity	5/524	49/18639	0.102040816326531	3.62965415173703	0.0118766855873285	0.0885070135873951
GO:0005009	insulin receptor activity	5/524	49/18639	0.102040816326531	3.62965415173703	0.0118766855873285	0.0885070135873951
GO:0005011	macrophage colony-stimulating factor receptor activity	5/524	49/18639	0.102040816326531	3.62965415173703	0.0118766855873285	0.0885070135873951
GO:0005018	platelet-derived growth factor alpha-receptor activity	5/524	49/18639	0.102040816326531	3.62965415173703	0.0118766855873285	0.0885070135873951
GO:0005020	stem cell factor receptor activity	5/524	49/18639	0.102040816326531	3.62965415173703	0.0118766855873285	0.0885070135873951
GO:0008288	boss receptor activity	5/524	49/18639	0.102040816326531	3.62965415173703	0.0118766855873285	0.0885070135873951
GO:0036332	placental growth factor receptor activity	5/524	49/18639	0.102040816326531	3.62965415173703	0.0118766855873285	0.0885070135873951
GO:0038062	protein tyrosine kinase collagen receptor activity	5/524	49/18639	0.102040816326531	3.62965415173703	0.0118766855873285	0.0885070135873951
GO:0060175	brain-derived neurotrophic factor receptor activity	5/524	49/18639	0.102040816326531	3.62965415173703	0.0118766855873285	0.0885070135873951
GO:0004197	cysteine-type endopeptidase activity	7/524	88/18639	0.0795454545454545	2.82948039555864	0.0119494595003577	0.0885070135873951
GO:0004222	metalloendopeptidase activity	8/524	110/18639	0.0727272727272727	2.58695350451076	0.0124395479864401	0.0913627305894845
GO:0005006	epidermal growth factor receptor activity	5/524	50/18639	0.1	3.55706106870229	0.0128995905467587	0.0916605051859111
GO:0005007	fibroblast growth factor receptor activity	5/524	50/18639	0.1	3.55706106870229	0.0128995905467587	0.0916605051859111
GO:0005017	platelet-derived growth factor receptor activity	5/524	50/18639	0.1	3.55706106870229	0.0128995905467587	0.0916605051859111
GO:0005019	platelet-derived growth factor beta-receptor activity	5/524	50/18639	0.1	3.55706106870229	0.0128995905467587	0.0916605051859111
GO:0035615	clathrin adaptor activity	3/524	18/18639	0.166666666666667	5.92843511450382	0.0131623894540951	0.0927736159909606
GO:0005010	insulin-like growth factor receptor activity	5/524	51/18639	0.0980392156862745	3.48731477323754	0.013980401113603	0.0963564441491398
GO:0005030	neurotrophin receptor activity	5/524	51/18639	0.0980392156862745	3.48731477323754	0.013980401113603	0.0963564441491398
GO:0140658	ATP-dependent chromatin remodeler activity	10/524	158/18639	0.0632911392405063	2.25130447386221	0.0140014512665226	0.0963564441491398
GO:0019825	oxygen binding	4/524	34/18639	0.117647058823529	4.18477772788505	0.0146908745651618	0.100311127890246
GO:0005080	protein kinase C binding	5/524	52/18639	0.0961538461538462	3.42025102759836	0.015120449683886	0.100606334969955
GO:0003689	DNA clamp loader activity	10/524	160/18639	0.0625	2.22316316793893	0.0151756182679254	0.100606334969955
GO:0061135	endopeptidase regulator activity	11/524	184/18639	0.0597826086956522	2.12650389976767	0.0151853766132975	0.100606334969955
GO:0034987	immunoglobulin receptor binding	3/524	19/18639	0.157894736842105	5.61641221374046	0.015309659669341	0.100606334969955
GO:0097001	ceramide binding	3/524	19/18639	0.157894736842105	5.61641221374046	0.015309659669341	0.100606334969955
GO:0017124	SH3 domain binding	8/524	115/18639	0.0695652173913043	2.4744772651842	0.0159270262892368	0.10235456600583
GO:0035401	histone H3Y41 kinase activity	8/524	115/18639	0.0695652173913043	2.4744772651842	0.0159270262892368	0.10235456600583
GO:0140801	histone H2AXY142 kinase activity	8/524	115/18639	0.0695652173913043	2.4744772651842	0.0159270262892368	0.10235456600583
GO:0005154	epidermal growth factor receptor binding	4/524	35/18639	0.114285714285714	4.06521264994547	0.0162270751237785	0.103366436227569
GO:0038064	collagen receptor activity	5/524	53/18639	0.0943396226415094	3.35571798934178	0.0163210162464583	0.103366436227569
GO:0008234	cysteine-type peptidase activity	11/524	187/18639	0.0588235294117647	2.09238886394252	0.0169333351592669	0.106472913159707
GO:0140597	protein carrier chaperone	11/524	188/18639	0.0585106382978723	2.08125913594283	0.0175481242481458	0.107683117431774
GO:0140463	chromatin-protein adaptor activity	5/524	54/18639	0.0925925925925926	3.29357506361323	0.017583326601364	0.107683117431774
GO:0000339	RNA cap binding	3/524	20/18639	0.15	5.33559160305343	0.0176423993827705	0.107683117431774
GO:0016004	phospholipase activator activity	3/524	20/18639	0.15	5.33559160305343	0.0176423993827705	0.107683117431774
GO:0140713	histone chaperone activity	10/524	164/18639	0.0609756097560976	2.16893967603798	0.0177418408583244	0.107683117431774
GO:0022853	active monoatomic ion transmembrane transporter activity	8/524	118/18639	0.0677966101694915	2.41156682623884	0.0183311972503541	0.110492871702134
GO:0001846	opsonin binding	3/524	21/18639	0.142857142857143	5.08151581243184	0.0201618044906739	0.119866746374789
GO:0140312	cargo adaptor activity	3/524	21/18639	0.142857142857143	5.08151581243184	0.0201618044906739	0.119866746374789
GO:0170055	lipid transmembrane transporter activity	5/524	56/18639	0.0892857142857143	3.1759473827699	0.0202978014456165	0.119866746374789
GO:0003697	single-stranded DNA binding	8/524	121/18639	0.0661157024793388	2.3517759131916	0.0209847108145884	0.123091525180874
GO:0003724	RNA helicase activity	6/524	77/18639	0.0779220779220779	2.7717358976901	0.0211997684536782	0.123523984190099
GO:0004601	peroxidase activity	5/524	57/18639	0.087719298245614	3.12022900763359	0.0217521329239466	0.125903074010128
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	5/524	59/18639	0.0847457627118644	3.01445853279855	0.0248599559589036	0.142010467373083
GO:0045309	protein phosphorylated amino acid binding	5/524	59/18639	0.0847457627118644	3.01445853279855	0.0248599559589036	0.142010467373083
GO:0004177	aminopeptidase activity	4/524	40/18639	0.1	3.55706106870229	0.0253938623931999	0.144118413841927
GO:0008137	NADH dehydrogenase (ubiquinone) activity	4/524	41/18639	0.0975609756097561	3.47030348166077	0.027533460538443	0.154257977632046
GO:0042287	MHC protein binding	4/524	41/18639	0.0975609756097561	3.47030348166077	0.027533460538443	0.154257977632046
GO:0031490	chromatin DNA binding	8/524	128/18639	0.0625	2.22316316793893	0.0282128516001124	0.156578771128962
GO:0019887	protein kinase regulator activity	13/524	255/18639	0.0509803921568627	1.81340368208352	0.0287650373107006	0.156578771128962
GO:0005540	hyaluronic acid binding	3/524	24/18639	0.125	4.44632633587786	0.0288434578395457	0.156578771128962
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/524	24/18639	0.125	4.44632633587786	0.0288434578395457	0.156578771128962
GO:0060229	lipase activator activity	3/524	24/18639	0.125	4.44632633587786	0.0288434578395457	0.156578771128962
GO:0005319	lipid transporter activity	10/524	178/18639	0.0561797752808989	1.99834891500129	0.02926025446887	0.157160369120281
GO:0008135	translation factor activity, RNA binding	6/524	83/18639	0.072289156626506	2.57136944725467	0.0293788425659696	0.157160369120281
GO:0003713	transcription coactivator activity	13/524	256/18639	0.05078125	1.80632007395038	0.0295615942794552	0.157160369120281
GO:0008307	structural constituent of muscle	4/524	42/18639	0.0952380952380952	3.3876772082879	0.0297774282911412	0.157160369120281
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/524	10/18639	0.2	7.11412213740458	0.0305689505153865	0.157160369120281
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/524	10/18639	0.2	7.11412213740458	0.0305689505153865	0.157160369120281
GO:0005031	tumor necrosis factor receptor activity	2/524	10/18639	0.2	7.11412213740458	0.0305689505153865	0.157160369120281
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/524	10/18639	0.2	7.11412213740458	0.0305689505153865	0.157160369120281
GO:0032395	MHC class II receptor activity	2/524	10/18639	0.2	7.11412213740458	0.0305689505153865	0.157160369120281
GO:0180051	translation factor activity	6/524	84/18639	0.0714285714285714	2.54075790621592	0.0309175807069958	0.158023190280201
GO:0004386	helicase activity	9/524	155/18639	0.0580645161290323	2.06539029795617	0.0312904387843236	0.158370189920592
GO:0019888	protein phosphatase regulator activity	7/524	107/18639	0.0654205607476635	2.32704929728187	0.0313478751215817	0.158370189920592
GO:0001848	complement binding	3/524	25/18639	0.12	4.26847328244275	0.0321104169472938	0.159457411431448
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/524	25/18639	0.12	4.26847328244275	0.0321104169472938	0.159457411431448
GO:0042974	nuclear retinoic acid receptor binding	3/524	25/18639	0.12	4.26847328244275	0.0321104169472938	0.159457411431448
GO:0046982	protein heterodimerization activity	17/524	369/18639	0.046070460704607	1.63875442189536	0.0325208210348246	0.160583037200207
GO:0019207	kinase regulator activity	14/524	287/18639	0.0487804878048781	1.73515174083039	0.032968296755611	0.161878041373056
GO:0003954	NADH dehydrogenase activity	4/524	44/18639	0.0909090909090909	3.23369188063845	0.0345810111171941	0.166959662714917
GO:0005160	transforming growth factor beta receptor binding	3/524	26/18639	0.115384615384615	4.10430123311803	0.0355620668938328	0.166959662714917
GO:0019865	immunoglobulin binding	3/524	26/18639	0.115384615384615	4.10430123311803	0.0355620668938328	0.166959662714917
GO:0034237	protein kinase A regulatory subunit binding	3/524	26/18639	0.115384615384615	4.10430123311803	0.0355620668938328	0.166959662714917
GO:0120013	lipid transfer activity	5/524	65/18639	0.0769230769230769	2.73620082207868	0.0358361387849335	0.166959662714917
GO:0015078	proton transmembrane transporter activity	10/524	185/18639	0.0540540540540541	1.92273571281205	0.0366680228315901	0.166959662714917
GO:0016176	superoxide-generating NADPH oxidase activator activity	2/524	11/18639	0.181818181818182	6.46738376127689	0.0366776375758171	0.166959662714917
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/524	11/18639	0.181818181818182	6.46738376127689	0.0366776375758171	0.166959662714917
GO:0019864	IgG binding	2/524	11/18639	0.181818181818182	6.46738376127689	0.0366776375758171	0.166959662714917
GO:0032050	clathrin heavy chain binding	2/524	11/18639	0.181818181818182	6.46738376127689	0.0366776375758171	0.166959662714917
GO:0034713	type I transforming growth factor beta receptor binding	2/524	11/18639	0.181818181818182	6.46738376127689	0.0366776375758171	0.166959662714917
GO:0048185	activin binding	2/524	11/18639	0.181818181818182	6.46738376127689	0.0366776375758171	0.166959662714917
GO:0048407	platelet-derived growth factor binding	2/524	11/18639	0.181818181818182	6.46738376127689	0.0366776375758171	0.166959662714917
GO:0140537	transcription regulator activator activity	2/524	11/18639	0.181818181818182	6.46738376127689	0.0366776375758171	0.166959662714917
GO:0008235	metalloexopeptidase activity	5/524	66/18639	0.0757575757575758	2.69474323386537	0.0379135443030225	0.17169138715462
GO:0004866	endopeptidase inhibitor activity	9/524	161/18639	0.0559006211180124	1.98841923095159	0.038469757075473	0.173312204556512
GO:0005200	structural constituent of cytoskeleton	7/524	112/18639	0.0625	2.22316316793893	0.0387371073795817	0.173621701793613
GO:0035255	ionotropic glutamate receptor binding	3/524	27/18639	0.111111111111111	3.95229007633588	0.0391966872345722	0.17478522777049
GO:0016500	protein-hormone receptor activity	5/524	67/18639	0.0746268656716418	2.65452318559872	0.0400631802024779	0.177742230949064
GO:0001784	phosphotyrosine residue binding	4/524	47/18639	0.0851063829787234	3.02728601591684	0.0425811569487756	0.183323178928073
GO:0046625	sphingolipid binding	3/524	28/18639	0.107142857142857	3.81113685932388	0.0430121949667375	0.183323178928073
GO:0051959	dynein light intermediate chain binding	3/524	28/18639	0.107142857142857	3.81113685932388	0.0430121949667375	0.183323178928073
GO:0000340	RNA 7-methylguanosine cap binding	2/524	12/18639	0.166666666666667	5.92843511450382	0.043208895719889	0.183323178928073
GO:0004875	complement receptor activity	2/524	12/18639	0.166666666666667	5.92843511450382	0.043208895719889	0.183323178928073
GO:0005078	MAP-kinase scaffold activity	2/524	12/18639	0.166666666666667	5.92843511450382	0.043208895719889	0.183323178928073
GO:0015132	prostaglandin transmembrane transporter activity	2/524	12/18639	0.166666666666667	5.92843511450382	0.043208895719889	0.183323178928073
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/524	12/18639	0.166666666666667	5.92843511450382	0.043208895719889	0.183323178928073
GO:1990247	N6-methyladenosine-containing RNA reader activity	2/524	12/18639	0.166666666666667	5.92843511450382	0.043208895719889	0.183323178928073
GO:0005096	GTPase activator activity	13/524	271/18639	0.0479704797047971	1.70633925804907	0.0435087606558487	0.183703656102472
GO:0015399	primary active transmembrane transporter activity	9/524	166/18639	0.0542168674698795	1.928527085441	0.0452502337195538	0.190106815536309
GO:0038187	pattern recognition receptor activity	4/524	48/18639	0.0833333333333333	2.96421755725191	0.0454603254543348	0.190106815536309
GO:0004629	phospholipase C activity	3/524	29/18639	0.103448275862069	3.6797183469334	0.0470061749051867	0.194521717365181
GO:0051213	dioxygenase activity	6/524	93/18639	0.0645161290322581	2.29487810884019	0.0471479469830318	0.194521717365181
GO:0019208	phosphatase regulator activity	7/524	117/18639	0.0598290598290598	2.12815619495009	0.0471837575302271	0.194521717365181
GO:0060590	ATPase regulator activity	4/524	49/18639	0.0816326530612245	2.90372332138962	0.0484455378869575	0.198785916024417
GO:0030414	peptidase inhibitor activity	9/524	169/18639	0.0532544378698225	1.8942928768237	0.0496793411383043	0.200996885190672
GO:0005035	death receptor activity	2/524	13/18639	0.153846153846154	5.47240164415737	0.0501342345212431	0.200996885190672
GO:0030955	potassium ion binding	2/524	13/18639	0.153846153846154	5.47240164415737	0.0501342345212431	0.200996885190672
GO:0071714	icosanoid transmembrane transporter activity	2/524	13/18639	0.153846153846154	5.47240164415737	0.0501342345212431	0.200996885190672
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/524	13/18639	0.153846153846154	5.47240164415737	0.0501342345212431	0.200996885190672
GO:0019955	cytokine binding	8/524	144/18639	0.0555555555555556	1.97614503816794	0.0507814263856975	0.201476324068726
GO:0031210	phosphatidylcholine binding	3/524	30/18639	0.1	3.55706106870229	0.0511759084018961	0.201476324068726
GO:0035925	mRNA 3'-UTR AU-rich region binding	3/524	30/18639	0.1	3.55706106870229	0.0511759084018961	0.201476324068726
GO:0048019	receptor antagonist activity	3/524	30/18639	0.1	3.55706106870229	0.0511759084018961	0.201476324068726
GO:0032813	tumor necrosis factor receptor superfamily binding	4/524	50/18639	0.08	2.84564885496183	0.0515364898295836	0.201986063278278
GO:0003743	translation initiation factor activity	4/524	51/18639	0.0784313725490196	2.78985181859003	0.0547327526990287	0.213555472584603
GO:0008191	metalloendopeptidase inhibitor activity	2/524	14/18639	0.142857142857143	5.08151581243184	0.0574264261600648	0.221104389708796
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/524	14/18639	0.142857142857143	5.08151581243184	0.0574264261600648	0.221104389708796
GO:0046030	inositol trisphosphate phosphatase activity	2/524	14/18639	0.142857142857143	5.08151581243184	0.0574264261600648	0.221104389708796
GO:0003725	double-stranded RNA binding	5/524	75/18639	0.0666666666666667	2.37137404580153	0.0598916633925469	0.228115540849142
GO:0044183	protein folding chaperone	5/524	75/18639	0.0666666666666667	2.37137404580153	0.0598916633925469	0.228115540849142
GO:0043425	bHLH transcription factor binding	3/524	32/18639	0.09375	3.3347447519084	0.0600304054866163	0.228115540849142
GO:0005085	guanyl-nucleotide exchange factor activity	11/524	230/18639	0.0478260869565217	1.70120311981414	0.0610280524519541	0.230170914689573
GO:0004252	serine-type endopeptidase activity	9/524	176/18639	0.0511363636363636	1.81895168285913	0.0610980002379644	0.230170914689573
GO:0051018	protein kinase A binding	4/524	53/18639	0.0754716981132075	2.68457439147343	0.061438901354685	0.230461801648046
GO:0098631	cell adhesion mediator activity	5/524	76/18639	0.0657894736842105	2.34017175572519	0.062700507172196	0.234189073797005
GO:0030296	protein tyrosine kinase activator activity	3/524	33/18639	0.0909090909090909	3.23369188063845	0.0647084512381292	0.236924856528104
GO:0071889	14-3-3 protein binding	3/524	33/18639	0.0909090909090909	3.23369188063845	0.0647084512381292	0.236924856528104
GO:0140416	transcription regulator inhibitor activity	3/524	33/18639	0.0909090909090909	3.23369188063845	0.0647084512381292	0.236924856528104
GO:0017069	snRNA binding	4/524	54/18639	0.0740740740740741	2.63486005089058	0.0649473473349508	0.236924856528104
GO:0000774	adenyl-nucleotide exchange factor activity	2/524	15/18639	0.133333333333333	4.74274809160305	0.0650594571701886	0.236924856528104
GO:0004129	cytochrome-c oxidase activity	2/524	15/18639	0.133333333333333	4.74274809160305	0.0650594571701886	0.236924856528104
GO:0003712	transcription coregulator activity	20/524	495/18639	0.0404040404040404	1.43719639139486	0.0675972141521003	0.244961333798796
GO:0008238	exopeptidase activity	6/524	102/18639	0.0588235294117647	2.09238886394252	0.067826822401955	0.244961333798796
GO:0098632	cell-cell adhesion mediator activity	4/524	55/18639	0.0727272727272727	2.58695350451076	0.0685582333417019	0.24658393391213
GO:0090482	vitamin transmembrane transporter activity	3/524	34/18639	0.0882352941176471	3.13858329591379	0.0695488618839003	0.248936050282681
GO:0005543	phospholipid binding	20/524	497/18639	0.0402414486921529	1.43141290491038	0.0697818447588752	0.248936050282681
GO:0035591	signaling adaptor activity	7/524	129/18639	0.0542635658914729	1.9301881768152	0.0719535634610496	0.255639896199014
GO:0005159	insulin-like growth factor receptor binding	2/524	16/18639	0.125	4.44632633587786	0.0730084818931994	0.256262703512676
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/524	16/18639	0.125	4.44632633587786	0.0730084818931994	0.256262703512676
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/524	16/18639	0.125	4.44632633587786	0.0730084818931994	0.256262703512676
GO:0008094	ATP-dependent activity, acting on DNA	10/524	210/18639	0.0476190476190476	1.69383860414395	0.0734283231896813	0.256705417871126
GO:0141003	histone H2AX kinase activity	15/524	354/18639	0.0423728813559322	1.50722926639928	0.0760811379249141	0.263876161397306
GO:0016504	peptidase activator activity	4/524	57/18639	0.0701754385964912	2.49618320610687	0.0760832868102072	0.263876161397306
GO:0001664	G protein-coupled receptor binding	13/524	297/18639	0.0437710437710438	1.55696275734444	0.0775171462324	0.267786505166473
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	4/524	58/18639	0.0689655172413793	2.45314556462227	0.0799951939983409	0.270008766565176
GO:0140996	histone H3 kinase activity	15/524	357/18639	0.0420168067226891	1.49456347424466	0.0803776989051373	0.270008766565176
GO:0005092	GDP-dissociation inhibitor activity	2/524	17/18639	0.117647058823529	4.18477772788505	0.0812497775819694	0.270008766565176
GO:0008429	phosphatidylethanolamine binding	2/524	17/18639	0.117647058823529	4.18477772788505	0.0812497775819694	0.270008766565176
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/524	17/18639	0.117647058823529	4.18477772788505	0.0812497775819694	0.270008766565176
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/524	17/18639	0.117647058823529	4.18477772788505	0.0812497775819694	0.270008766565176
GO:0046965	nuclear retinoid X receptor binding	2/524	17/18639	0.117647058823529	4.18477772788505	0.0812497775819694	0.270008766565176
GO:0048038	quinone binding	2/524	17/18639	0.117647058823529	4.18477772788505	0.0812497775819694	0.270008766565176
GO:0051787	misfolded protein binding	2/524	17/18639	0.117647058823529	4.18477772788505	0.0812497775819694	0.270008766565176
GO:1990226	histone methyltransferase binding	2/524	17/18639	0.117647058823529	4.18477772788505	0.0812497775819694	0.270008766565176
GO:0001786	phosphatidylserine binding	4/524	59/18639	0.0677966101694915	2.41156682623884	0.0840050294921181	0.272499774147868
GO:0004879	nuclear receptor activity	4/524	59/18639	0.0677966101694915	2.41156682623884	0.0840050294921181	0.272499774147868
GO:0015459	potassium channel regulator activity	4/524	59/18639	0.0677966101694915	2.41156682623884	0.0840050294921181	0.272499774147868
GO:0036002	pre-mRNA binding	4/524	59/18639	0.0677966101694915	2.41156682623884	0.0840050294921181	0.272499774147868
GO:0070063	RNA polymerase binding	4/524	59/18639	0.0677966101694915	2.41156682623884	0.0840050294921181	0.272499774147868
GO:0070888	E-box binding	4/524	59/18639	0.0677966101694915	2.41156682623884	0.0840050294921181	0.272499774147868
GO:0051087	protein-folding chaperone binding	7/524	134/18639	0.0522388059701493	1.85816622991911	0.0841818524255426	0.272499774147868
GO:0035173	histone kinase activity	15/524	360/18639	0.0416666666666667	1.48210877862595	0.0848286596068426	0.273580252754171
GO:0004860	protein kinase inhibitor activity	5/524	84/18639	0.0595238095238095	2.11729825517993	0.0877784979376448	0.278194513331956
GO:0051117	ATPase binding	5/524	84/18639	0.0595238095238095	2.11729825517993	0.0877784979376448	0.278194513331956
GO:0098531	ligand-modulated transcription factor activity	4/524	60/18639	0.0666666666666667	2.37137404580153	0.0881114420248333	0.278194513331956
GO:0042578	phosphoric ester hydrolase activity	15/524	363/18639	0.0413223140495868	1.46985994574475	0.0894348021426489	0.278194513331956
GO:0000400	four-way junction DNA binding	2/524	18/18639	0.111111111111111	3.95229007633588	0.0897607010979537	0.278194513331956
GO:0008525	phosphatidylcholine transporter activity	2/524	18/18639	0.111111111111111	3.95229007633588	0.0897607010979537	0.278194513331956
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/524	18/18639	0.111111111111111	3.95229007633588	0.0897607010979537	0.278194513331956
GO:0034185	apolipoprotein binding	2/524	18/18639	0.111111111111111	3.95229007633588	0.0897607010979537	0.278194513331956
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	2/524	18/18639	0.111111111111111	3.95229007633588	0.0897607010979537	0.278194513331956
GO:0050811	GABA receptor binding	2/524	18/18639	0.111111111111111	3.95229007633588	0.0897607010979537	0.278194513331956
GO:1990381	ubiquitin-specific protease binding	2/524	18/18639	0.111111111111111	3.95229007633588	0.0897607010979537	0.278194513331956
GO:0016922	nuclear receptor binding	7/524	137/18639	0.0510948905109489	1.81747645846102	0.0920557098485298	0.284299259390866
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	5/524	86/18639	0.0581395348837209	2.06805876087342	0.0947564943467746	0.291609774855919
GO:0000217	DNA secondary structure binding	3/524	39/18639	0.0769230769230769	2.73620082207868	0.0960460830469864	0.29287813472001
GO:0008236	serine-type peptidase activity	9/524	194/18639	0.0463917525773196	1.65018297001653	0.097642993126498	0.29287813472001
GO:0008081	phosphoric diester hydrolase activity	5/524	87/18639	0.0574712643678161	2.04428797051856	0.0983485922689407	0.29287813472001
GO:0008301	DNA binding, bending	2/524	19/18639	0.105263157894737	3.74427480916031	0.0985196471483787	0.29287813472001
GO:0015245	fatty acid transmembrane transporter activity	2/524	19/18639	0.105263157894737	3.74427480916031	0.0985196471483787	0.29287813472001
GO:0031420	alkali metal ion binding	2/524	19/18639	0.105263157894737	3.74427480916031	0.0985196471483787	0.29287813472001
GO:0042834	peptidoglycan binding	2/524	19/18639	0.105263157894737	3.74427480916031	0.0985196471483787	0.29287813472001
GO:0043395	heparan sulfate proteoglycan binding	2/524	19/18639	0.105263157894737	3.74427480916031	0.0985196471483787	0.29287813472001
GO:0140036	ubiquitin-modified protein reader activity	2/524	19/18639	0.105263157894737	3.74427480916031	0.0985196471483787	0.29287813472001
GO:1990380	K48-linked deubiquitinase activity	2/524	19/18639	0.105263157894737	3.74427480916031	0.0985196471483787	0.29287813472001
GO:0032451	demethylase activity	3/524	40/18639	0.075	2.66779580152672	0.101774641478375	0.298487950852478
GO:0050997	quaternary ammonium group binding	3/524	40/18639	0.075	2.66779580152672	0.101774641478375	0.298487950852478
GO:0140662	ATP-dependent protein folding chaperone	3/524	40/18639	0.075	2.66779580152672	0.101774641478375	0.298487950852478
GO:0016651	oxidoreductase activity, acting on NAD(P)H	5/524	88/18639	0.0568181818181818	2.02105742539903	0.102008469981113	0.298487950852478
GO:0005201	extracellular matrix structural constituent	8/524	168/18639	0.0476190476190476	1.69383860414395	0.102114298975848	0.298487950852478
GO:0001221	transcription coregulator binding	6/524	115/18639	0.0521739130434783	1.85585794888815	0.105623365600237	0.307018951221907
GO:0003727	single-stranded RNA binding	5/524	89/18639	0.0561797752808989	1.99834891500129	0.105735359631343	0.307018951221907
GO:0017171	serine hydrolase activity	9/524	198/18639	0.0454545454545455	1.61684594031922	0.107177970266682	0.307430320709002
GO:0001614	purinergic nucleotide receptor activity	2/524	20/18639	0.1	3.55706106870229	0.107506008011224	0.307430320709002
GO:0016502	nucleotide receptor activity	2/524	20/18639	0.1	3.55706106870229	0.107506008011224	0.307430320709002
GO:0052745	inositol phosphate phosphatase activity	2/524	20/18639	0.1	3.55706106870229	0.107506008011224	0.307430320709002
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	3/524	41/18639	0.0731707317073171	2.60272761124558	0.107635787342053	0.307430320709002
GO:0019210	kinase inhibitor activity	5/524	90/18639	0.0555555555555556	1.97614503816794	0.109528452834586	0.311817158884131
GO:0005123	death receptor binding	2/524	21/18639	0.0952380952380952	3.3876772082879	0.116700134697598	0.331155577031495
GO:0004712	protein serine/threonine/tyrosine kinase activity	3/524	43/18639	0.0697674418604651	2.48167051304811	0.119737275946023	0.337581868312336
GO:0008375	acetylglucosaminyltransferase activity	3/524	43/18639	0.0697674418604651	2.48167051304811	0.119737275946023	0.337581868312336
GO:0051219	phosphoprotein binding	5/524	93/18639	0.0537634408602151	1.91239842403349	0.12129629267101	0.340877684226568
GO:0003714	transcription corepressor activity	9/524	204/18639	0.0441176470588235	1.56929164795689	0.122425911143011	0.342949507496767
GO:0005548	phospholipid transporter activity	4/524	68/18639	0.0588235294117647	2.09238886394252	0.124252744232426	0.345849995092802
GO:0032934	sterol binding	4/524	68/18639	0.0588235294117647	2.09238886394252	0.124252744232426	0.345849995092802
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/524	22/18639	0.0909090909090909	3.23369188063845	0.126083299502757	0.346530829450973
GO:0061133	endopeptidase activator activity	2/524	22/18639	0.0909090909090909	3.23369188063845	0.126083299502757	0.346530829450973
GO:0140035	ubiquitin-like protein reader activity	2/524	22/18639	0.0909090909090909	3.23369188063845	0.126083299502757	0.346530829450973
GO:0140517	protein-RNA adaptor activity	2/524	22/18639	0.0909090909090909	3.23369188063845	0.126083299502757	0.346530829450973
GO:0140303	intramembrane lipid transporter activity	3/524	45/18639	0.0666666666666667	2.37137404580153	0.132312986307205	0.362512696026636
GO:0030276	clathrin binding	3/524	46/18639	0.0652173913043478	2.31982243611019	0.138766808014062	0.377879246058716
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	8/524	181/18639	0.0441988950276243	1.57218168782422	0.138786313483808	0.377879246058716
GO:0004725	protein tyrosine phosphatase activity	5/524	98/18639	0.0510204081632653	1.81482707586852	0.142147308631048	0.385828409141415
GO:0061749	forked DNA-dependent helicase activity	3/524	47/18639	0.0638297872340425	2.27046451193763	0.145324920586695	0.388478897654982
GO:1990518	single-stranded 3'-5' DNA helicase activity	3/524	47/18639	0.0638297872340425	2.27046451193763	0.145324920586695	0.388478897654982
GO:0015149	hexose transmembrane transporter activity	2/524	24/18639	0.0833333333333333	2.96421755725191	0.145346223722173	0.388478897654982
GO:0035035	histone acetyltransferase binding	2/524	24/18639	0.0833333333333333	2.96421755725191	0.145346223722173	0.388478897654982
GO:0055056	D-glucose transmembrane transporter activity	2/524	24/18639	0.0833333333333333	2.96421755725191	0.145346223722173	0.388478897654982
GO:0009378	four-way junction helicase activity	3/524	48/18639	0.0625	2.22316316793893	0.151982560262185	0.402523508088333
GO:0036121	double-stranded DNA helicase activity	3/524	48/18639	0.0625	2.22316316793893	0.151982560262185	0.402523508088333
GO:0043138	3'-5' DNA helicase activity	3/524	48/18639	0.0625	2.22316316793893	0.151982560262185	0.402523508088333
GO:0140097	catalytic activity, acting on DNA	13/524	336/18639	0.0386904761904762	1.37624386586696	0.154035284905323	0.406103355832545
GO:0031491	nucleosome binding	4/524	74/18639	0.0540540540540541	1.92273571281205	0.154819347769571	0.406103355832545
GO:0048029	monosaccharide binding	4/524	74/18639	0.0540540540540541	1.92273571281205	0.154819347769571	0.406103355832545
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/524	25/18639	0.08	2.84564885496183	0.155192815615641	0.406103355832545
GO:0035254	glutamate receptor binding	3/524	49/18639	0.0612244897959184	2.17779249104222	0.158734974764918	0.414132441625486
GO:0016298	lipase activity	6/524	130/18639	0.0461538461538462	1.64172049324721	0.160092841504563	0.416431974627942
GO:0031072	heat shock protein binding	6/524	131/18639	0.0458015267175573	1.62918827574151	0.164095213024056	0.420850224625777
GO:0004435	phosphatidylinositol phospholipase C activity	2/524	26/18639	0.0769230769230769	2.73620082207868	0.165162044675791	0.420850224625777
GO:0005112	Notch binding	2/524	26/18639	0.0769230769230769	2.73620082207868	0.165162044675791	0.420850224625777
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	2/524	26/18639	0.0769230769230769	2.73620082207868	0.165162044675791	0.420850224625777
GO:0008143	poly(A) binding	2/524	26/18639	0.0769230769230769	2.73620082207868	0.165162044675791	0.420850224625777
GO:0015145	monosaccharide transmembrane transporter activity	2/524	26/18639	0.0769230769230769	2.73620082207868	0.165162044675791	0.420850224625777
GO:0070412	R-SMAD binding	2/524	26/18639	0.0769230769230769	2.73620082207868	0.165162044675791	0.420850224625777
GO:0030246	carbohydrate binding	11/524	280/18639	0.0392857142857143	1.39741684841876	0.167076231559642	0.424490192974206
GO:0008083	growth factor activity	7/524	162/18639	0.0432098765432099	1.53700169635284	0.172416050976431	0.436787329140291
GO:0015252	proton channel activity	2/524	27/18639	0.0740740740740741	2.63486005089058	0.175239273271089	0.439066440488567
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	2/524	27/18639	0.0740740740740741	2.63486005089058	0.175239273271089	0.439066440488567
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	2/524	27/18639	0.0740740740740741	2.63486005089058	0.175239273271089	0.439066440488567
GO:0031267	small GTPase binding	11/524	283/18639	0.03886925795053	1.38260324225177	0.175325157586396	0.439066440488567
GO:0030159	signaling receptor complex adaptor activity	3/524	52/18639	0.0576923076923077	2.05215061655901	0.17951367951935	0.448271302571177
GO:0044325	transmembrane transporter binding	6/524	136/18639	0.0441176470588235	1.56929164795689	0.184726548244624	0.454280772331107
GO:0019789	SUMO transferase activity	2/524	28/18639	0.0714285714285714	2.54075790621592	0.185410586986808	0.454280772331107
GO:0046875	ephrin receptor binding	2/524	28/18639	0.0714285714285714	2.54075790621592	0.185410586986808	0.454280772331107
GO:0051119	sugar transmembrane transporter activity	2/524	28/18639	0.0714285714285714	2.54075790621592	0.185410586986808	0.454280772331107
GO:0097718	disordered domain specific binding	2/524	28/18639	0.0714285714285714	2.54075790621592	0.185410586986808	0.454280772331107
GO:0141052	histone H3 demethylase activity	2/524	28/18639	0.0714285714285714	2.54075790621592	0.185410586986808	0.454280772331107
GO:0005246	calcium channel regulator activity	3/524	53/18639	0.0566037735849057	2.01343079360507	0.18659816620923	0.454280772331107
GO:0005544	calcium-dependent phospholipid binding	3/524	53/18639	0.0566037735849057	2.01343079360507	0.18659816620923	0.454280772331107
GO:0140296	general transcription initiation factor binding	3/524	53/18639	0.0566037735849057	2.01343079360507	0.18659816620923	0.454280772331107
GO:0048306	calcium-dependent protein binding	4/524	80/18639	0.05	1.77853053435115	0.187865593292124	0.455156872553989
GO:0004843	cysteine-type deubiquitinase activity	5/524	108/18639	0.0462962962962963	1.64678753180662	0.187999577794039	0.455156872553989
GO:0004620	phospholipase activity	5/524	109/18639	0.0458715596330275	1.63167938931298	0.192853801517125	0.456444961032641
GO:0033192	calmodulin-dependent protein phosphatase activity	4/524	81/18639	0.0493827160493827	1.75657336726039	0.193581387335228	0.456444961032641
GO:0140791	histone H2AXS140 phosphatase activity	4/524	81/18639	0.0493827160493827	1.75657336726039	0.193581387335228	0.456444961032641
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	4/524	81/18639	0.0493827160493827	1.75657336726039	0.193581387335228	0.456444961032641
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	4/524	81/18639	0.0493827160493827	1.75657336726039	0.193581387335228	0.456444961032641
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	4/524	81/18639	0.0493827160493827	1.75657336726039	0.193581387335228	0.456444961032641
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	4/524	81/18639	0.0493827160493827	1.75657336726039	0.193581387335228	0.456444961032641
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	4/524	81/18639	0.0493827160493827	1.75657336726039	0.193581387335228	0.456444961032641
GO:1990439	MAP kinase serine/threonine phosphatase activity	4/524	81/18639	0.0493827160493827	1.75657336726039	0.193581387335228	0.456444961032641
GO:0015485	cholesterol binding	3/524	54/18639	0.0555555555555556	1.97614503816794	0.193754096731247	0.456444961032641
GO:0106222	lncRNA binding	2/524	29/18639	0.0689655172413793	2.45314556462227	0.195662765659521	0.459702304264573
GO:0030295	protein kinase activator activity	6/524	139/18639	0.0431654676258993	1.53542204404415	0.197571409507934	0.461704309919609
GO:0070851	growth factor receptor binding	6/524	139/18639	0.0431654676258993	1.53542204404415	0.197571409507934	0.461704309919609
GO:0016887	ATP hydrolysis activity	15/524	417/18639	0.0359712230215827	1.27951837003679	0.19844258895112	0.462155207530295
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	4/524	82/18639	0.0487804878048781	1.73515174083039	0.199350701646363	0.462155207530295
GO:0033549	MAP kinase phosphatase activity	4/524	82/18639	0.0487804878048781	1.73515174083039	0.199350701646363	0.462155207530295
GO:1902936	phosphatidylinositol bisphosphate binding	5/524	111/18639	0.045045045045045	1.60227976067671	0.202692274783687	0.468247637832292
GO:0141108	transporter regulator activity	7/524	170/18639	0.0411764705882353	1.46467220475977	0.203050177046269	0.468247637832292
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	4/524	83/18639	0.0481927710843374	1.71424629816978	0.205171298209163	0.470050562076289
GO:0001965	G-protein alpha-subunit binding	2/524	30/18639	0.0666666666666667	2.37137404580153	0.205983255463637	0.470050562076289
GO:0032452	histone demethylase activity	2/524	30/18639	0.0666666666666667	2.37137404580153	0.205983255463637	0.470050562076289
GO:0051721	protein phosphatase 2A binding	2/524	30/18639	0.0666666666666667	2.37137404580153	0.205983255463637	0.470050562076289
GO:0020037	heme binding	6/524	142/18639	0.0422535211267606	1.5029835501559	0.210737586942654	0.479090337679673
GO:0017018	myosin phosphatase activity	4/524	84/18639	0.0476190476190476	1.69383860414395	0.211040938222739	0.479090337679673
GO:0005164	tumor necrosis factor receptor binding	2/524	31/18639	0.0645161290322581	2.29487810884019	0.216360142013918	0.488627297468125
GO:0140457	protein demethylase activity	2/524	31/18639	0.0645161290322581	2.29487810884019	0.216360142013918	0.488627297468125
GO:0022804	active transmembrane transporter activity	16/524	457/18639	0.0350109409190372	1.24536054921743	0.218042078886566	0.491156641615616
GO:0101005	deubiquitinase activity	5/524	115/18639	0.0434782608695652	1.54654829074013	0.222851953080282	0.497453030022197
GO:0017116	single-stranded DNA helicase activity	3/524	58/18639	0.0517241379310345	1.8398591734667	0.223002398048005	0.497453030022197
GO:0031369	translation initiation factor binding	2/524	32/18639	0.0625	2.22316316793893	0.226782124449072	0.497453030022197
GO:0070717	poly-purine tract binding	2/524	32/18639	0.0625	2.22316316793893	0.226782124449072	0.497453030022197
GO:0008514	organic anion transmembrane transporter activity	10/524	269/18639	0.0371747211895911	1.32232753483357	0.22713376972658	0.497453030022197
GO:0031593	polyubiquitin modification-dependent protein binding	3/524	59/18639	0.0508474576271186	1.80867511967913	0.230448685649214	0.497453030022197
GO:0043021	ribonucleoprotein complex binding	7/524	177/18639	0.0395480225988701	1.40674731530599	0.231429790753414	0.497453030022197
GO:1990782	protein tyrosine kinase binding	5/524	117/18639	0.0427350427350427	1.52011156782149	0.233151548024415	0.497453030022197
GO:0019209	kinase activator activity	6/524	148/18639	0.0405405405405405	1.44205178460904	0.23793722558398	0.497453030022197
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	3/524	60/18639	0.05	1.77853053435115	0.237940119524181	0.497453030022197
GO:0004674	protein serine/threonine kinase activity	15/524	433/18639	0.0346420323325635	1.23223824550888	0.239346271680437	0.497453030022197
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	4/524	89/18639	0.0449438202247191	1.59867913200103	0.241046665247029	0.497453030022197
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	4/524	89/18639	0.0449438202247191	1.59867913200103	0.241046665247029	0.497453030022197
GO:0140793	histone H2AXY142 phosphatase activity	4/524	90/18639	0.0444444444444444	1.58091603053435	0.247163791405747	0.497453030022197
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/524	34/18639	0.0588235294117647	2.09238886394252	0.247719092248855	0.497453030022197
GO:0030332	cyclin binding	2/524	34/18639	0.0588235294117647	2.09238886394252	0.247719092248855	0.497453030022197
GO:0051427	hormone receptor binding	2/524	34/18639	0.0588235294117647	2.09238886394252	0.247719092248855	0.497453030022197
GO:0052866	phosphatidylinositol phosphate phosphatase activity	2/524	34/18639	0.0588235294117647	2.09238886394252	0.247719092248855	0.497453030022197
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0004955	prostaglandin receptor activity	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0005131	growth hormone receptor binding	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0005345	purine nucleobase transmembrane transporter activity	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0005381	iron ion transmembrane transporter activity	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0005522	profilin binding	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0016427	tRNA (cytidine) methyltransferase activity	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0030957	Tat protein binding	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0031996	thioesterase binding	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0042975	peroxisome proliferator activated receptor binding	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0043208	glycosphingolipid binding	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0043422	protein kinase B binding	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0050815	phosphoserine residue binding	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0051880	G-quadruplex DNA binding	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0070513	death domain binding	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0098505	G-rich strand telomeric DNA binding	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0099122	RNA polymerase II C-terminal domain binding	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0140940	histone H2A methyltransferase activity	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0141109	transporter activator activity	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:1990259	histone H2AQ104 methyltransferase activity	1/524	10/18639	0.1	3.55706106870229	0.248157346784528	0.497453030022197
GO:0072341	modified amino acid binding	4/524	91/18639	0.043956043956044	1.56354332690211	0.253314452981454	0.502933435201963
GO:0046906	tetrapyrrole binding	6/524	152/18639	0.0394736842105263	1.40410305343511	0.256632910604319	0.502933435201963
GO:0043178	alcohol binding	4/524	92/18639	0.0434782608695652	1.54654829074013	0.259496481640941	0.502933435201963
GO:0003774	cytoskeletal motor activity	6/524	153/18639	0.0392156862745098	1.39492590929502	0.261368570188121	0.502933435201963
GO:1901981	phosphatidylinositol phosphate binding	7/524	185/18639	0.0378378378378378	1.34591499896843	0.265362763811227	0.502933435201963
GO:0045505	dynein intermediate chain binding	2/524	36/18639	0.0555555555555556	1.97614503816794	0.268715096243558	0.502933435201963
GO:0000099	sulfur amino acid transmembrane transporter activity	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0002162	dystroglycan binding	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0004954	prostanoid receptor activity	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0005114	type II transforming growth factor beta receptor binding	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0008046	axon guidance receptor activity	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0008199	ferric iron binding	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0008432	JUN kinase binding	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0008526	phosphatidylinositol transfer activity	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0010854	adenylate cyclase regulator activity	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0015173	aromatic amino acid transmembrane transporter activity	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0015205	nucleobase transmembrane transporter activity	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0015217	ADP transmembrane transporter activity	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0019215	intermediate filament binding	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0031731	CCR6 chemokine receptor binding	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0032794	GTPase activating protein binding	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0050786	RAGE receptor binding	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0070697	activin receptor binding	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0070990	snRNP binding	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0097493	structural molecule activity conferring elasticity	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0140031	phosphorylation-dependent protein binding	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0180030	inositol phosphate kinase activity	1/524	11/18639	0.0909090909090909	3.23369188063845	0.269305317705399	0.502933435201963
GO:0051020	GTPase binding	11/524	315/18639	0.0349206349206349	1.24214830970556	0.273929048962128	0.510477588044563
GO:0004867	serine-type endopeptidase inhibitor activity	4/524	95/18639	0.0421052631578947	1.49770992366412	0.278209351515428	0.512828413182745
GO:0035091	phosphatidylinositol binding	10/524	284/18639	0.0352112676056338	1.25248629179658	0.278583481279469	0.512828413182745
GO:0019213	deacetylase activity	2/524	37/18639	0.0540540540540541	1.92273571281205	0.27921282103621	0.512828413182745
GO:0019783	ubiquitin-like protein peptidase activity	5/524	127/18639	0.0393700787401575	1.40041774358358	0.286410777910356	0.512828413182745
GO:0042826	histone deacetylase binding	5/524	127/18639	0.0393700787401575	1.40041774358358	0.286410777910356	0.512828413182745
GO:0000146	microfilament motor activity	2/524	38/18639	0.0526315789473684	1.87213740458015	0.289699384573722	0.512828413182745
GO:0003995	acyl-CoA dehydrogenase activity	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0005095	GTPase inhibitor activity	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0005165	neurotrophin receptor binding	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0008603	cAMP-dependent protein kinase regulator activity	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0010853	cyclase activator activity	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0015368	calcium:monoatomic cation antiporter activity	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0016273	arginine N-methyltransferase activity	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0016274	protein-arginine N-methyltransferase activity	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0016801	hydrolase activity, acting on ether bonds	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0016803	ether hydrolase activity	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0017166	vinculin binding	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0035497	cAMP response element binding	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0036009	protein-glutamine N-methyltransferase activity	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0043047	single-stranded telomeric DNA binding	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0097677	STAT family protein binding	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/524	12/18639	0.0833333333333333	2.96421755725191	0.289859537885899	0.512828413182745
GO:0003777	microtubule motor activity	3/524	68/18639	0.0441176470588235	1.56929164795689	0.299016336979861	0.527960158627068
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/524	13/18639	0.0769230769230769	2.73620082207868	0.309836646499621	0.536232136714195
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/524	13/18639	0.0769230769230769	2.73620082207868	0.309836646499621	0.536232136714195
GO:0008035	high-density lipoprotein particle binding	1/524	13/18639	0.0769230769230769	2.73620082207868	0.309836646499621	0.536232136714195
GO:0019855	calcium channel inhibitor activity	1/524	13/18639	0.0769230769230769	2.73620082207868	0.309836646499621	0.536232136714195
GO:0031994	insulin-like growth factor I binding	1/524	13/18639	0.0769230769230769	2.73620082207868	0.309836646499621	0.536232136714195
GO:0043560	insulin receptor substrate binding	1/524	13/18639	0.0769230769230769	2.73620082207868	0.309836646499621	0.536232136714195
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/524	13/18639	0.0769230769230769	2.73620082207868	0.309836646499621	0.536232136714195
GO:0051011	microtubule minus-end binding	1/524	13/18639	0.0769230769230769	2.73620082207868	0.309836646499621	0.536232136714195
GO:0097157	pre-mRNA intronic binding	1/524	13/18639	0.0769230769230769	2.73620082207868	0.309836646499621	0.536232136714195
GO:0140333	glycerophospholipid flippase activity	1/524	13/18639	0.0769230769230769	2.73620082207868	0.309836646499621	0.536232136714195
GO:0015144	carbohydrate transmembrane transporter activity	2/524	40/18639	0.05	1.77853053435115	0.310608840556079	0.536506179142319
GO:0008028	monocarboxylic acid transmembrane transporter activity	3/524	70/18639	0.0428571428571429	1.52445474372955	0.314465608631813	0.542096532434329
GO:0106310	protein serine kinase activity	12/524	361/18639	0.0332409972299169	1.18240257131378	0.317841453289426	0.546837460974327
GO:0015175	neutral L-amino acid transmembrane transporter activity	2/524	41/18639	0.0487804878048781	1.73515174083039	0.321017715079875	0.551217058899432
GO:0004722	protein serine/threonine phosphatase activity	4/524	103/18639	0.0388349514563107	1.38138293930186	0.32896877783664	0.557687911464738
GO:0005347	ATP transmembrane transporter activity	1/524	14/18639	0.0714285714285714	2.54075790621592	0.329252817294971	0.557687911464738
GO:0008494	translation activator activity	1/524	14/18639	0.0714285714285714	2.54075790621592	0.329252817294971	0.557687911464738
GO:0019992	diacylglycerol binding	1/524	14/18639	0.0714285714285714	2.54075790621592	0.329252817294971	0.557687911464738
GO:0034236	protein kinase A catalytic subunit binding	1/524	14/18639	0.0714285714285714	2.54075790621592	0.329252817294971	0.557687911464738
GO:0070742	C2H2 zinc finger domain binding	1/524	14/18639	0.0714285714285714	2.54075790621592	0.329252817294971	0.557687911464738
GO:0098847	sequence-specific single stranded DNA binding	1/524	14/18639	0.0714285714285714	2.54075790621592	0.329252817294971	0.557687911464738
GO:0043175	RNA polymerase core enzyme binding	2/524	42/18639	0.0476190476190476	1.69383860414395	0.331387356239648	0.559136195663035
GO:0051879	Hsp90 protein binding	2/524	42/18639	0.0476190476190476	1.69383860414395	0.331387356239648	0.559136195663035
GO:0016247	channel regulator activity	6/524	168/18639	0.0357142857142857	1.27037895310796	0.334612164986291	0.563489464736067
GO:0140789	histone phosphatase activity	5/524	136/18639	0.0367647058823529	1.30774303996408	0.336047072697954	0.564817579880792
GO:0004521	RNA endonuclease activity	3/524	73/18639	0.0410958904109589	1.46180591864478	0.337662369034232	0.566443206402915
GO:0003678	DNA helicase activity	3/524	74/18639	0.0405405405405405	1.44205178460904	0.345388130496119	0.568710610036092
GO:0004559	alpha-mannosidase activity	1/524	15/18639	0.0666666666666667	2.37137404580153	0.348123771589599	0.568710610036092
GO:0004953	icosanoid receptor activity	1/524	15/18639	0.0666666666666667	2.37137404580153	0.348123771589599	0.568710610036092
GO:0015929	hexosaminidase activity	1/524	15/18639	0.0666666666666667	2.37137404580153	0.348123771589599	0.568710610036092
GO:0016846	carbon-sulfur lyase activity	1/524	15/18639	0.0666666666666667	2.37137404580153	0.348123771589599	0.568710610036092
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/524	15/18639	0.0666666666666667	2.37137404580153	0.348123771589599	0.568710610036092
GO:0017081	chloride channel regulator activity	1/524	15/18639	0.0666666666666667	2.37137404580153	0.348123771589599	0.568710610036092
GO:0031005	filamin binding	1/524	15/18639	0.0666666666666667	2.37137404580153	0.348123771589599	0.568710610036092
GO:0033130	acetylcholine receptor binding	1/524	15/18639	0.0666666666666667	2.37137404580153	0.348123771589599	0.568710610036092
GO:0047372	monoacylglycerol lipase activity	1/524	15/18639	0.0666666666666667	2.37137404580153	0.348123771589599	0.568710610036092
GO:0050780	dopamine receptor binding	1/524	15/18639	0.0666666666666667	2.37137404580153	0.348123771589599	0.568710610036092
GO:0120283	protein serine/threonine kinase binding	1/524	15/18639	0.0666666666666667	2.37137404580153	0.348123771589599	0.568710610036092
GO:0141050	histone H3K deacetylase activity	1/524	15/18639	0.0666666666666667	2.37137404580153	0.348123771589599	0.568710610036092
GO:0141051	histone H4K deacetylase activity	1/524	15/18639	0.0666666666666667	2.37137404580153	0.348123771589599	0.568710610036092
GO:0001046	core promoter sequence-specific DNA binding	2/524	44/18639	0.0454545454545455	1.61684594031922	0.351985251745422	0.572877299861264
GO:0030020	extracellular matrix structural constituent conferring tensile strength	2/524	44/18639	0.0454545454545455	1.61684594031922	0.351985251745422	0.572877299861264
GO:0140030	modification-dependent protein binding	6/524	173/18639	0.0346820809248555	1.23366279839386	0.359621481513134	0.576061559800275
GO:0005496	steroid binding	4/524	108/18639	0.037037037037037	1.31743002544529	0.360987308202721	0.576061559800275
GO:0016791	phosphatase activity	9/524	273/18639	0.032967032967033	1.17265749517658	0.361144308673687	0.576061559800275
GO:0004715	non-membrane spanning protein tyrosine kinase activity	2/524	45/18639	0.0444444444444444	1.58091603053435	0.362202566416967	0.576061559800275
GO:0046915	transition metal ion transmembrane transporter activity	2/524	45/18639	0.0444444444444444	1.58091603053435	0.362202566416967	0.576061559800275
GO:0141110	transporter inhibitor activity	2/524	45/18639	0.0444444444444444	1.58091603053435	0.362202566416967	0.576061559800275
GO:0000062	fatty-acyl-CoA binding	1/524	16/18639	0.0625	2.22316316793893	0.366464790902692	0.576061559800275
GO:0003688	DNA replication origin binding	1/524	16/18639	0.0625	2.22316316793893	0.366464790902692	0.576061559800275
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/524	16/18639	0.0625	2.22316316793893	0.366464790902692	0.576061559800275
GO:0008142	oxysterol binding	1/524	16/18639	0.0625	2.22316316793893	0.366464790902692	0.576061559800275
GO:0015923	mannosidase activity	1/524	16/18639	0.0625	2.22316316793893	0.366464790902692	0.576061559800275
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/524	16/18639	0.0625	2.22316316793893	0.366464790902692	0.576061559800275
GO:0022858	alanine transmembrane transporter activity	1/524	16/18639	0.0625	2.22316316793893	0.366464790902692	0.576061559800275
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/524	16/18639	0.0625	2.22316316793893	0.366464790902692	0.576061559800275
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/524	16/18639	0.0625	2.22316316793893	0.366464790902692	0.576061559800275
GO:0070411	I-SMAD binding	1/524	16/18639	0.0625	2.22316316793893	0.366464790902692	0.576061559800275
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/524	16/18639	0.0625	2.22316316793893	0.366464790902692	0.576061559800275
GO:0140327	flippase activity	1/524	16/18639	0.0625	2.22316316793893	0.366464790902692	0.576061559800275
GO:0140328	floppase activity	1/524	16/18639	0.0625	2.22316316793893	0.366464790902692	0.576061559800275
GO:0004721	phosphoprotein phosphatase activity	6/524	175/18639	0.0342857142857143	1.21956379498364	0.369662084895438	0.580044276837725
GO:0004180	carboxypeptidase activity	2/524	46/18639	0.0434782608695652	1.54654829074013	0.372358737253463	0.582185217101121
GO:0030291	protein serine/threonine kinase inhibitor activity	2/524	46/18639	0.0434782608695652	1.54654829074013	0.372358737253463	0.582185217101121
GO:0005504	fatty acid binding	2/524	47/18639	0.0425531914893617	1.51364300795842	0.382449129105319	0.583107807902079
GO:0033293	monocarboxylic acid binding	3/524	79/18639	0.0379746835443038	1.35078268431733	0.38383765343464	0.583107807902079
GO:0004029	aldehyde dehydrogenase (NAD+) activity	1/524	17/18639	0.0588235294117647	2.09238886394252	0.384290729235237	0.583107807902079
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/524	17/18639	0.0588235294117647	2.09238886394252	0.384290729235237	0.583107807902079
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/524	17/18639	0.0588235294117647	2.09238886394252	0.384290729235237	0.583107807902079
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/524	17/18639	0.0588235294117647	2.09238886394252	0.384290729235237	0.583107807902079
GO:0008484	sulfuric ester hydrolase activity	1/524	17/18639	0.0588235294117647	2.09238886394252	0.384290729235237	0.583107807902079
GO:0008569	minus-end-directed microtubule motor activity	1/524	17/18639	0.0588235294117647	2.09238886394252	0.384290729235237	0.583107807902079
GO:0019198	transmembrane receptor protein phosphatase activity	1/524	17/18639	0.0588235294117647	2.09238886394252	0.384290729235237	0.583107807902079
GO:0030548	acetylcholine receptor regulator activity	1/524	17/18639	0.0588235294117647	2.09238886394252	0.384290729235237	0.583107807902079
GO:0032183	SUMO binding	1/524	17/18639	0.0588235294117647	2.09238886394252	0.384290729235237	0.583107807902079
GO:0036041	long-chain fatty acid binding	1/524	17/18639	0.0588235294117647	2.09238886394252	0.384290729235237	0.583107807902079
GO:0038191	neuropilin binding	1/524	17/18639	0.0588235294117647	2.09238886394252	0.384290729235237	0.583107807902079
GO:0045125	bioactive lipid receptor activity	1/524	17/18639	0.0588235294117647	2.09238886394252	0.384290729235237	0.583107807902079
GO:0045236	CXCR chemokine receptor binding	1/524	17/18639	0.0588235294117647	2.09238886394252	0.384290729235237	0.583107807902079
GO:0070403	NAD+ binding	1/524	17/18639	0.0588235294117647	2.09238886394252	0.384290729235237	0.583107807902079
GO:1901567	fatty acid derivative binding	1/524	17/18639	0.0588235294117647	2.09238886394252	0.384290729235237	0.583107807902079
GO:0008194	UDP-glycosyltransferase activity	5/524	145/18639	0.0344827586206897	1.22657278231113	0.386322967861463	0.584551378708662
GO:0043022	ribosome binding	4/524	112/18639	0.0357142857142857	1.27037895310796	0.386579744729527	0.584551378708662
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	2/524	48/18639	0.0416666666666667	1.48210877862595	0.392469414707195	0.588946989692968
GO:0035402	histone H3T11 kinase activity	8/524	247/18639	0.0323886639676113	1.15208455666471	0.392715553206001	0.588946989692968
GO:0042393	histone binding	8/524	247/18639	0.0323886639676113	1.15208455666471	0.392715553206001	0.588946989692968
GO:0030971	receptor tyrosine kinase binding	3/524	81/18639	0.037037037037037	1.31743002544529	0.399084141627047	0.588946989692968
GO:0000900	mRNA regulatory element binding translation repressor activity	1/524	18/18639	0.0555555555555556	1.97614503816794	0.401616025008019	0.588946989692968
GO:0003746	translation elongation factor activity	1/524	18/18639	0.0555555555555556	1.97614503816794	0.401616025008019	0.588946989692968
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	1/524	18/18639	0.0555555555555556	1.97614503816794	0.401616025008019	0.588946989692968
GO:0004706	JUN kinase kinase kinase activity	1/524	18/18639	0.0555555555555556	1.97614503816794	0.401616025008019	0.588946989692968
GO:0008409	5'-3' exonuclease activity	1/524	18/18639	0.0555555555555556	1.97614503816794	0.401616025008019	0.588946989692968
GO:0015172	acidic amino acid transmembrane transporter activity	1/524	18/18639	0.0555555555555556	1.97614503816794	0.401616025008019	0.588946989692968
GO:0016854	racemase and epimerase activity	1/524	18/18639	0.0555555555555556	1.97614503816794	0.401616025008019	0.588946989692968
GO:0017128	phospholipid scramblase activity	1/524	18/18639	0.0555555555555556	1.97614503816794	0.401616025008019	0.588946989692968
GO:0031690	adrenergic receptor binding	1/524	18/18639	0.0555555555555556	1.97614503816794	0.401616025008019	0.588946989692968
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/524	18/18639	0.0555555555555556	1.97614503816794	0.401616025008019	0.588946989692968
GO:0070628	proteasome binding	1/524	18/18639	0.0555555555555556	1.97614503816794	0.401616025008019	0.588946989692968
GO:0098641	cadherin binding involved in cell-cell adhesion	1/524	18/18639	0.0555555555555556	1.97614503816794	0.401616025008019	0.588946989692968
GO:0099602	neurotransmitter receptor regulator activity	1/524	18/18639	0.0555555555555556	1.97614503816794	0.401616025008019	0.588946989692968
GO:1901611	phosphatidylglycerol binding	1/524	18/18639	0.0555555555555556	1.97614503816794	0.401616025008019	0.588946989692968
GO:0001222	transcription corepressor binding	2/524	49/18639	0.0408163265306122	1.45186166069481	0.402415561087718	0.589130988929088
GO:0140098	catalytic activity, acting on RNA	12/524	387/18639	0.0310077519379845	1.10296467246583	0.405975694584474	0.593349092085
GO:0015605	organophosphate ester transmembrane transporter activity	2/524	50/18639	0.04	1.42282442748092	0.412283816497616	0.601562697193517
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/524	19/18639	0.0526315789473684	1.87213740458015	0.418454712666888	0.605512282898775
GO:0005520	insulin-like growth factor binding	1/524	19/18639	0.0526315789473684	1.87213740458015	0.418454712666888	0.605512282898775
GO:0030506	ankyrin binding	1/524	19/18639	0.0526315789473684	1.87213740458015	0.418454712666888	0.605512282898775
GO:0046624	sphingolipid transporter activity	1/524	19/18639	0.0526315789473684	1.87213740458015	0.418454712666888	0.605512282898775
GO:0120227	acyl-CoA binding	1/524	19/18639	0.0526315789473684	1.87213740458015	0.418454712666888	0.605512282898775
GO:0004527	exonuclease activity	3/524	84/18639	0.0357142857142857	1.27037895310796	0.421750457953709	0.609272562399243
GO:0010851	cyclase regulator activity	1/524	20/18639	0.05	1.77853053435115	0.434820433964554	0.623005015221345
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/524	20/18639	0.05	1.77853053435115	0.434820433964554	0.623005015221345
GO:0030742	GTP-dependent protein binding	1/524	20/18639	0.05	1.77853053435115	0.434820433964554	0.623005015221345
GO:0031418	L-ascorbic acid binding	1/524	20/18639	0.05	1.77853053435115	0.434820433964554	0.623005015221345
GO:0140939	histone H4 methyltransferase activity	1/524	20/18639	0.05	1.77853053435115	0.434820433964554	0.623005015221345
GO:0032182	ubiquitin-like protein binding	4/524	120/18639	0.0333333333333333	1.18568702290076	0.43726699372058	0.625485028660863
GO:0004864	protein phosphatase inhibitor activity	2/524	53/18639	0.0377358490566038	1.34228719573671	0.441387677094666	0.629319461306261
GO:1901505	carbohydrate derivative transmembrane transporter activity	2/524	53/18639	0.0377358490566038	1.34228719573671	0.441387677094666	0.629319461306261
GO:0004540	RNA nuclease activity	4/524	121/18639	0.0330578512396694	1.1758879565958	0.443527891602968	0.629548127521308
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/524	21/18639	0.0476190476190476	1.69383860414395	0.450726448927902	0.629548127521308
GO:0015125	bile acid transmembrane transporter activity	1/524	21/18639	0.0476190476190476	1.69383860414395	0.450726448927902	0.629548127521308
GO:0035613	RNA stem-loop binding	1/524	21/18639	0.0476190476190476	1.69383860414395	0.450726448927902	0.629548127521308
GO:0036122	BMP binding	1/524	21/18639	0.0476190476190476	1.69383860414395	0.450726448927902	0.629548127521308
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/524	21/18639	0.0476190476190476	1.69383860414395	0.450726448927902	0.629548127521308
GO:0051428	peptide hormone receptor binding	1/524	21/18639	0.0476190476190476	1.69383860414395	0.450726448927902	0.629548127521308
GO:0061891	calcium ion sensor activity	1/524	21/18639	0.0476190476190476	1.69383860414395	0.450726448927902	0.629548127521308
GO:0070182	DNA polymerase binding	1/524	21/18639	0.0476190476190476	1.69383860414395	0.450726448927902	0.629548127521308
GO:0072542	protein phosphatase activator activity	1/524	21/18639	0.0476190476190476	1.69383860414395	0.450726448927902	0.629548127521308
GO:0003925	G protein activity	2/524	54/18639	0.037037037037037	1.31743002544529	0.450912045570182	0.629548127521308
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	2/524	54/18639	0.037037037037037	1.31743002544529	0.450912045570182	0.629548127521308
GO:0051287	NAD binding	2/524	54/18639	0.037037037037037	1.31743002544529	0.450912045570182	0.629548127521308
GO:0004407	histone deacetylase activity	1/524	22/18639	0.0454545454545455	1.61684594031922	0.466185646519576	0.644693441547641
GO:0031683	G-protein beta/gamma-subunit complex binding	1/524	22/18639	0.0454545454545455	1.61684594031922	0.466185646519576	0.644693441547641
GO:0033558	protein lysine deacetylase activity	1/524	22/18639	0.0454545454545455	1.61684594031922	0.466185646519576	0.644693441547641
GO:0050321	tau-protein kinase activity	1/524	22/18639	0.0454545454545455	1.61684594031922	0.466185646519576	0.644693441547641
GO:0070034	telomerase RNA binding	1/524	22/18639	0.0454545454545455	1.61684594031922	0.466185646519576	0.644693441547641
GO:0140784	metal ion sensor activity	1/524	22/18639	0.0454545454545455	1.61684594031922	0.466185646519576	0.644693441547641
GO:0099106	ion channel regulator activity	5/524	160/18639	0.03125	1.11158158396947	0.469270684256703	0.646457067176964
GO:0019212	phosphatase inhibitor activity	2/524	56/18639	0.0357142857142857	1.27037895310796	0.469679905786467	0.646457067176964
GO:0030170	pyridoxal phosphate binding	2/524	56/18639	0.0357142857142857	1.27037895310796	0.469679905786467	0.646457067176964
GO:0070279	vitamin B6 binding	2/524	57/18639	0.0350877192982456	1.24809160305344	0.478918976044134	0.648040100265101
GO:0016758	hexosyltransferase activity	6/524	197/18639	0.0304568527918782	1.08336885341187	0.479409332248521	0.648040100265101
GO:0004519	endonuclease activity	4/524	127/18639	0.031496062992126	1.12033419486686	0.480608091959775	0.648040100265101
GO:0052689	carboxylic ester hydrolase activity	3/524	92/18639	0.0326086956521739	1.15991121805509	0.480609630928208	0.648040100265101
GO:0000295	adenine nucleotide transmembrane transporter activity	1/524	23/18639	0.0434782608695652	1.54654829074013	0.481210555002346	0.648040100265101
GO:0003887	DNA-directed DNA polymerase activity	1/524	23/18639	0.0434782608695652	1.54654829074013	0.481210555002346	0.648040100265101
GO:0004602	glutathione peroxidase activity	1/524	23/18639	0.0434782608695652	1.54654829074013	0.481210555002346	0.648040100265101
GO:0005158	insulin receptor binding	1/524	23/18639	0.0434782608695652	1.54654829074013	0.481210555002346	0.648040100265101
GO:0005212	structural constituent of eye lens	1/524	23/18639	0.0434782608695652	1.54654829074013	0.481210555002346	0.648040100265101
GO:0005283	amino acid:sodium symporter activity	1/524	23/18639	0.0434782608695652	1.54654829074013	0.481210555002346	0.648040100265101
GO:0017134	fibroblast growth factor binding	1/524	23/18639	0.0434782608695652	1.54654829074013	0.481210555002346	0.648040100265101
GO:0043274	phospholipase binding	1/524	23/18639	0.0434782608695652	1.54654829074013	0.481210555002346	0.648040100265101
GO:0070577	lysine-acetylated histone binding	1/524	23/18639	0.0434782608695652	1.54654829074013	0.481210555002346	0.648040100265101
GO:0140103	catalytic activity, acting on a glycoprotein	1/524	23/18639	0.0434782608695652	1.54654829074013	0.481210555002346	0.648040100265101
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	4/524	128/18639	0.03125	1.11158158396947	0.486696554324863	0.654419674584508
GO:0016829	lyase activity	6/524	200/18639	0.03	1.06711832061069	0.494026330247231	0.65558376650635
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/524	24/18639	0.0416666666666667	1.48210877862595	0.495813352014528	0.65558376650635
GO:0005315	phosphate transmembrane transporter activity	1/524	24/18639	0.0416666666666667	1.48210877862595	0.495813352014528	0.65558376650635
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/524	24/18639	0.0416666666666667	1.48210877862595	0.495813352014528	0.65558376650635
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/524	24/18639	0.0416666666666667	1.48210877862595	0.495813352014528	0.65558376650635
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/524	24/18639	0.0416666666666667	1.48210877862595	0.495813352014528	0.65558376650635
GO:0050431	transforming growth factor beta binding	1/524	24/18639	0.0416666666666667	1.48210877862595	0.495813352014528	0.65558376650635
GO:0050699	WW domain binding	1/524	24/18639	0.0416666666666667	1.48210877862595	0.495813352014528	0.65558376650635
GO:0070300	phosphatidic acid binding	1/524	24/18639	0.0416666666666667	1.48210877862595	0.495813352014528	0.65558376650635
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/524	24/18639	0.0416666666666667	1.48210877862595	0.495813352014528	0.65558376650635
GO:0140033	acetylation-dependent protein binding	1/524	24/18639	0.0416666666666667	1.48210877862595	0.495813352014528	0.65558376650635
GO:0004709	MAP kinase kinase kinase activity	1/524	25/18639	0.04	1.42282442748092	0.510005874364481	0.669286988280115
GO:0005537	D-mannose binding	1/524	25/18639	0.04	1.42282442748092	0.510005874364481	0.669286988280115
GO:0008139	nuclear localization sequence binding	1/524	25/18639	0.04	1.42282442748092	0.510005874364481	0.669286988280115
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/524	25/18639	0.04	1.42282442748092	0.510005874364481	0.669286988280115
GO:0019211	phosphatase activator activity	1/524	25/18639	0.04	1.42282442748092	0.510005874364481	0.669286988280115
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	2/524	61/18639	0.0327868852459016	1.16624953072206	0.514866879841519	0.671699377469674
GO:0015179	L-amino acid transmembrane transporter activity	2/524	62/18639	0.032258064516129	1.14743905442009	0.523594378132814	0.671699377469674
GO:0004529	DNA exonuclease activity	1/524	26/18639	0.0384615384615385	1.36810041103934	0.523799627552029	0.671699377469674
GO:0008198	ferrous iron binding	1/524	26/18639	0.0384615384615385	1.36810041103934	0.523799627552029	0.671699377469674
GO:0015216	purine nucleotide transmembrane transporter activity	1/524	26/18639	0.0384615384615385	1.36810041103934	0.523799627552029	0.671699377469674
GO:0030247	polysaccharide binding	1/524	26/18639	0.0384615384615385	1.36810041103934	0.523799627552029	0.671699377469674
GO:0050681	nuclear androgen receptor binding	1/524	26/18639	0.0384615384615385	1.36810041103934	0.523799627552029	0.671699377469674
GO:0120014	phospholipid transfer activity	1/524	26/18639	0.0384615384615385	1.36810041103934	0.523799627552029	0.671699377469674
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	7/524	243/18639	0.0288065843621399	1.02466779756856	0.527513377860592	0.671699377469674
GO:0005507	copper ion binding	2/524	63/18639	0.0317460317460317	1.12922573609596	0.532215693634231	0.671699377469674
GO:0004676	3-phosphoinositide-dependent protein kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0004711	ribosomal protein S6 kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0035175	histone H3S10 kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0035979	histone H2AXS139 kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0044022	histone H3S28 kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0044023	histone H4S1 kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0044024	histone H2AS1 kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0044025	histone H2BS14 kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0072354	histone H3T3 kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0072371	histone H2AS121 kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0072518	Rho-dependent protein serine/threonine kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0140823	histone H2BS36 kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0140855	histone H3S57 kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0140995	histone H2A kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0140997	histone H4 kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0140998	histone H2B kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:1990244	histone H2AT120 kinase activity	7/524	245/18639	0.0285714285714286	1.01630316248637	0.53621774049803	0.671699377469674
GO:0043130	ubiquitin binding	3/524	100/18639	0.03	1.06711832061069	0.536496284285142	0.671699377469674
GO:0004518	nuclease activity	6/524	209/18639	0.0287081339712919	1.02116585704372	0.536985983976103	0.671699377469674
GO:0001671	ATPase activator activity	1/524	27/18639	0.037037037037037	1.31743002544529	0.537205795024373	0.671699377469674
GO:0004364	glutathione transferase activity	1/524	27/18639	0.037037037037037	1.31743002544529	0.537205795024373	0.671699377469674
GO:0005385	zinc ion transmembrane transporter activity	1/524	27/18639	0.037037037037037	1.31743002544529	0.537205795024373	0.671699377469674
GO:0008320	protein transmembrane transporter activity	1/524	27/18639	0.037037037037037	1.31743002544529	0.537205795024373	0.671699377469674
GO:0004677	DNA-dependent protein kinase activity	7/524	246/18639	0.0284552845528455	1.01217184881772	0.540545956429418	0.673947454949089
GO:0140857	histone H3T45 kinase activity	7/524	246/18639	0.0284552845528455	1.01217184881772	0.540545956429418	0.673947454949089
GO:0035403	histone H3T6 kinase activity	7/524	247/18639	0.0283400809716599	1.00807398708162	0.544857676523435	0.67835556877704
GO:0160215	deacylase activity	2/524	65/18639	0.0307692307692308	1.09448032883147	0.549136164941606	0.681169413640226
GO:0004679	AMP-activated protein kinase activity	7/524	248/18639	0.0282258064516129	1.00400917261758	0.549152522194224	0.681169413640226
GO:0051019	mitogen-activated protein kinase binding	1/524	28/18639	0.0357142857142857	1.27037895310796	0.550235247173913	0.681169413640226
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	1/524	28/18639	0.0357142857142857	1.27037895310796	0.550235247173913	0.681169413640226
GO:0004181	metallocarboxypeptidase activity	1/524	29/18639	0.0344827586206897	1.22657278231113	0.562898550085141	0.691945615716474
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/524	29/18639	0.0344827586206897	1.22657278231113	0.562898550085141	0.691945615716474
GO:0005416	amino acid:monoatomic cation symporter activity	1/524	29/18639	0.0344827586206897	1.22657278231113	0.562898550085141	0.691945615716474
GO:0051861	glycolipid binding	1/524	29/18639	0.0344827586206897	1.22657278231113	0.562898550085141	0.691945615716474
GO:0097472	cyclin-dependent protein kinase activity	1/524	29/18639	0.0344827586206897	1.22657278231113	0.562898550085141	0.691945615716474
GO:0050840	extracellular matrix binding	2/524	67/18639	0.0298507462686567	1.06180927423949	0.565622392514954	0.694317375081558
GO:0030145	manganese ion binding	2/524	68/18639	0.0294117647058824	1.04619443197126	0.573701363894805	0.700277539764177
GO:1990841	promoter-specific chromatin binding	2/524	68/18639	0.0294117647058824	1.04619443197126	0.573701363894805	0.700277539764177
GO:0008187	poly-pyrimidine tract binding	1/524	30/18639	0.0333333333333333	1.18568702290076	0.575205974037607	0.700277539764177
GO:0015215	nucleotide transmembrane transporter activity	1/524	30/18639	0.0333333333333333	1.18568702290076	0.575205974037607	0.700277539764177
GO:0033612	receptor serine/threonine kinase binding	1/524	30/18639	0.0333333333333333	1.18568702290076	0.575205974037607	0.700277539764177
GO:0004497	monooxygenase activity	3/524	106/18639	0.0283018867924528	1.00671539680253	0.576086442895244	0.700277539764177
GO:0008013	beta-catenin binding	3/524	106/18639	0.0283018867924528	1.00671539680253	0.576086442895244	0.700277539764177
GO:0005452	solute:inorganic anion antiporter activity	1/524	31/18639	0.032258064516129	1.14743905442009	0.587167501771729	0.71176754028917
GO:0070273	phosphatidylinositol-4-phosphate binding	1/524	31/18639	0.032258064516129	1.14743905442009	0.587167501771729	0.71176754028917
GO:0140299	molecular sensor activity	2/524	71/18639	0.028169014084507	1.00198903343726	0.597278142370226	0.721855088444193
GO:0022884	macromolecule transmembrane transporter activity	1/524	32/18639	0.03125	1.11158158396947	0.598792836524073	0.721855088444193
GO:0042910	xenobiotic transmembrane transporter activity	1/524	32/18639	0.03125	1.11158158396947	0.598792836524073	0.721855088444193
GO:0051059	NF-kappaB binding	1/524	32/18639	0.03125	1.11158158396947	0.598792836524073	0.721855088444193
GO:0003730	mRNA 3'-UTR binding	7/524	262/18639	0.0267175572519084	0.950359827515879	0.60731663430188	0.731122229173337
GO:0019956	chemokine binding	1/524	33/18639	0.0303030303030303	1.07789729354615	0.610091409838492	0.732444906866541
GO:0042923	neuropeptide binding	1/524	33/18639	0.0303030303030303	1.07789729354615	0.610091409838492	0.732444906866541
GO:0046943	carboxylic acid transmembrane transporter activity	5/524	188/18639	0.0265957446808511	0.946026879974013	0.612145697401111	0.733255962843568
GO:0043539	protein serine/threonine kinase activator activity	2/524	73/18639	0.0273972602739726	0.974537279096518	0.612444911757214	0.733255962843568
GO:0005342	organic acid transmembrane transporter activity	5/524	189/18639	0.0264550264550265	0.941021446746638	0.616826856551645	0.73749202821633
GO:0008175	tRNA methyltransferase activity	1/524	34/18639	0.0294117647058824	1.04619443197126	0.62107238915939	0.737523462126776
GO:0008376	acetylgalactosaminyltransferase activity	1/524	34/18639	0.0294117647058824	1.04619443197126	0.62107238915939	0.737523462126776
GO:0015020	glucuronosyltransferase activity	1/524	34/18639	0.0294117647058824	1.04619443197126	0.62107238915939	0.737523462126776
GO:0015035	protein-disulfide reductase activity	1/524	34/18639	0.0294117647058824	1.04619443197126	0.62107238915939	0.737523462126776
GO:0016831	carboxy-lyase activity	1/524	34/18639	0.0294117647058824	1.04619443197126	0.62107238915939	0.737523462126776
GO:0000287	magnesium ion binding	6/524	230/18639	0.0260869565217391	0.927928974444076	0.630392338553189	0.745134756918092
GO:0005343	organic acid:sodium symporter activity	1/524	35/18639	0.0285714285714286	1.01630316248637	0.631744685213165	0.745134756918092
GO:0034061	DNA polymerase activity	1/524	35/18639	0.0285714285714286	1.01630316248637	0.631744685213165	0.745134756918092
GO:0043015	gamma-tubulin binding	1/524	35/18639	0.0285714285714286	1.01630316248637	0.631744685213165	0.745134756918092
GO:0140566	histone reader activity	1/524	35/18639	0.0285714285714286	1.01630316248637	0.631744685213165	0.745134756918092
GO:0000993	RNA polymerase II complex binding	1/524	36/18639	0.0277777777777778	0.988072519083969	0.642116959183725	0.753302311847753
GO:0004190	aspartic-type endopeptidase activity	1/524	36/18639	0.0277777777777778	0.988072519083969	0.642116959183725	0.753302311847753
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/524	36/18639	0.0277777777777778	0.988072519083969	0.642116959183725	0.753302311847753
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/524	36/18639	0.0277777777777778	0.988072519083969	0.642116959183725	0.753302311847753
GO:0030280	structural constituent of skin epidermis	1/524	37/18639	0.027027027027027	0.961367856406024	0.652197629687822	0.763079957626716
GO:0070001	aspartic-type peptidase activity	1/524	37/18639	0.027027027027027	0.961367856406024	0.652197629687822	0.763079957626716
GO:0015370	solute:sodium symporter activity	2/524	79/18639	0.0253164556962025	0.900521789544884	0.655314100385314	0.765701234942198
GO:0008017	microtubule binding	7/524	276/18639	0.0253623188405797	0.902153169598407	0.661283333473328	0.771444699642326
GO:0042162	telomeric DNA binding	1/524	38/18639	0.0263157894736842	0.936068702290076	0.661994879555771	0.771444699642326
GO:0015101	organic cation transmembrane transporter activity	2/524	81/18639	0.0246913580246914	0.878286683630195	0.668737362866793	0.778264254521408
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	1/524	39/18639	0.0256410256410256	0.912066940692895	0.67151666242297	0.780459525209676
GO:0004532	RNA exonuclease activity	1/524	40/18639	0.025	0.889265267175573	0.680770709137506	0.782886315508132
GO:0015036	disulfide oxidoreductase activity	1/524	40/18639	0.025	0.889265267175573	0.680770709137506	0.782886315508132
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/524	40/18639	0.025	0.889265267175573	0.680770709137506	0.782886315508132
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	1/524	40/18639	0.025	0.889265267175573	0.680770709137506	0.782886315508132
GO:0061791	GTPase motor activity	1/524	40/18639	0.025	0.889265267175573	0.680770709137506	0.782886315508132
GO:0071855	neuropeptide receptor binding	1/524	40/18639	0.025	0.889265267175573	0.680770709137506	0.782886315508132
GO:0071949	FAD binding	1/524	40/18639	0.025	0.889265267175573	0.680770709137506	0.782886315508132
GO:1990606	membrane scission GTPase motor activity	1/524	40/18639	0.025	0.889265267175573	0.680770709137506	0.782886315508132
GO:0001727	lipid kinase activity	1/524	41/18639	0.024390243902439	0.867575870415193	0.689764533988947	0.789076181552801
GO:0017080	sodium channel regulator activity	1/524	41/18639	0.024390243902439	0.867575870415193	0.689764533988947	0.789076181552801
GO:0140318	protein transporter activity	1/524	41/18639	0.024390243902439	0.867575870415193	0.689764533988947	0.789076181552801
GO:0140828	metal cation:monoatomic cation antiporter activity	1/524	41/18639	0.024390243902439	0.867575870415193	0.689764533988947	0.789076181552801
GO:0019894	kinesin binding	1/524	42/18639	0.0238095238095238	0.846919302071974	0.69850544076332	0.795950137193145
GO:0031492	nucleosomal DNA binding	1/524	42/18639	0.0238095238095238	0.846919302071974	0.69850544076332	0.795950137193145
GO:0048487	beta-tubulin binding	1/524	42/18639	0.0238095238095238	0.846919302071974	0.69850544076332	0.795950137193145
GO:0015291	secondary active transmembrane transporter activity	7/524	287/18639	0.024390243902439	0.867575870415193	0.700380264205233	0.796086444666546
GO:0050660	flavin adenine dinucleotide binding	2/524	86/18639	0.0232558139534884	0.82722350434937	0.700446768819878	0.796086444666546
GO:0008200	ion channel inhibitor activity	1/524	43/18639	0.0232558139534884	0.82722350434937	0.707000528629106	0.802491509119271
GO:0016798	hydrolase activity, acting on glycosyl bonds	3/524	130/18639	0.0230769230769231	0.820860246623605	0.71188661590297	0.806989497145519
GO:0016248	channel inhibitor activity	1/524	44/18639	0.0227272727272727	0.808422970159611	0.715256697858959	0.808711971447258
GO:0043014	alpha-tubulin binding	1/524	44/18639	0.0227272727272727	0.808422970159611	0.715256697858959	0.808711971447258
GO:0003924	GTPase activity	8/524	331/18639	0.0241691842900302	0.859712645003575	0.716475291153248	0.809043158227311
GO:0005179	hormone activity	3/524	132/18639	0.0227272727272727	0.808422970159611	0.721531052846595	0.813700826048934
GO:0051539	4 iron, 4 sulfur cluster binding	1/524	45/18639	0.0222222222222222	0.790458015267176	0.723280655391732	0.814622800015945
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	2/524	91/18639	0.021978021978022	0.781771663451053	0.729596739189844	0.820234886122084
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/524	46/18639	0.0217391304347826	0.773274145370063	0.731078920239249	0.820234886122084
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/524	46/18639	0.0217391304347826	0.773274145370063	0.731078920239249	0.820234886122084
GO:0015297	antiporter activity	3/524	135/18639	0.0222222222222222	0.790458015267176	0.735524220204941	0.824164318537332
GO:0043495	protein-membrane adaptor activity	1/524	47/18639	0.0212765957446809	0.756821503979211	0.73865782874216	0.824366254950502
GO:0140359	ABC-type transporter activity	1/524	47/18639	0.0212765957446809	0.756821503979211	0.73865782874216	0.824366254950502
GO:0140938	histone H3 methyltransferase activity	1/524	47/18639	0.0212765957446809	0.756821503979211	0.73865782874216	0.824366254950502
GO:0005525	GTP binding	9/524	378/18639	0.0238095238095238	0.846919302071974	0.739477281328597	0.824366254950502
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/524	48/18639	0.0208333333333333	0.741054389312977	0.746023539679075	0.830604552457976
GO:0016853	isomerase activity	4/524	180/18639	0.0222222222222222	0.790458015267176	0.748725346790221	0.832552103173859
GO:0016763	pentosyltransferase activity	1/524	49/18639	0.0204081632653061	0.725930830347406	0.753182039233061	0.836443586136843
GO:0015631	tubulin binding	9/524	385/18639	0.0233766233766234	0.831520769307029	0.75845128801536	0.841226428585565
GO:0016757	glycosyltransferase activity	6/524	267/18639	0.0224719101123595	0.799339566000515	0.765101309732233	0.845234615279899
GO:0042626	ATPase-coupled transmembrane transporter activity	2/524	98/18639	0.0204081632653061	0.725930830347406	0.766336007018983	0.845234615279899
GO:0005048	signal sequence binding	1/524	51/18639	0.0196078431372549	0.697462954647508	0.76690051477913	0.845234615279899
GO:0016830	carbon-carbon lyase activity	1/524	51/18639	0.0196078431372549	0.697462954647508	0.76690051477913	0.845234615279899
GO:0030544	Hsp70 protein binding	1/524	51/18639	0.0196078431372549	0.697462954647508	0.76690051477913	0.845234615279899
GO:0031406	carboxylic acid binding	4/524	187/18639	0.0213903743315508	0.760868677797281	0.77471178186832	0.852768384575456
GO:0008146	sulfotransferase activity	1/524	53/18639	0.0188679245283019	0.671143597868357	0.779857873052492	0.856276106844067
GO:0016860	intramolecular oxidoreductase activity	1/524	53/18639	0.0188679245283019	0.671143597868357	0.779857873052492	0.856276106844067
GO:0043177	organic acid binding	4/524	189/18639	0.0211640211640212	0.75281715739731	0.781735967088363	0.857261273820865
GO:0015171	amino acid transmembrane transporter activity	2/524	102/18639	0.0196078431372549	0.697462954647508	0.785323304921593	0.859850167633057
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	1/524	54/18639	0.0185185185185185	0.658715012722646	0.786064398099328	0.859850167633057
GO:0019001	guanyl nucleotide binding	9/524	400/18639	0.0225	0.800338740458015	0.795798467766745	0.868324420509532
GO:0032561	guanyl ribonucleotide binding	9/524	400/18639	0.0225	0.800338740458015	0.795798467766745	0.868324420509532
GO:0019842	vitamin binding	3/524	150/18639	0.02	0.711412213740458	0.7972889169704	0.868865976848041
GO:0000149	SNARE binding	2/524	106/18639	0.0188679245283019	0.671143597868357	0.80294167735588	0.873625520732479
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/524	57/18639	0.0175438596491228	0.624045801526718	0.80365551335116	0.873625520732479
GO:0008408	3'-5' exonuclease activity	1/524	58/18639	0.0172413793103448	0.613286391155567	0.809192296851536	0.878551636581667
GO:0001098	basal transcription machinery binding	1/524	60/18639	0.0166666666666667	0.592843511450382	0.819802710181643	0.885670665882269
GO:0001099	basal RNA polymerase II transcription machinery binding	1/524	60/18639	0.0166666666666667	0.592843511450382	0.819802710181643	0.885670665882269
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/524	60/18639	0.0166666666666667	0.592843511450382	0.819802710181643	0.885670665882269
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/524	60/18639	0.0166666666666667	0.592843511450382	0.819802710181643	0.885670665882269
GO:0015026	coreceptor activity	1/524	61/18639	0.0163934426229508	0.583124765361031	0.824884974020645	0.890061070733387
GO:1901682	sulfur compound transmembrane transporter activity	1/524	63/18639	0.0158730158730159	0.564612868047982	0.834624300737859	0.899459480696534
GO:0005516	calmodulin binding	4/524	207/18639	0.0193236714975845	0.6873547958845	0.837361308985222	0.901297763612173
GO:0004536	DNA nuclease activity	1/524	64/18639	0.015625	0.555790791984733	0.839289291393186	0.90226179665147
GO:0015294	solute:monoatomic cation symporter activity	2/524	116/18639	0.0172413793103448	0.613286391155567	0.841483034128279	0.903508810599651
GO:0015081	sodium ion transmembrane transporter activity	3/524	164/18639	0.0182926829268293	0.650681902811394	0.84359817363401	0.903800544498467
GO:0019843	rRNA binding	1/524	65/18639	0.0153846153846154	0.547240164415737	0.843822933993992	0.903800544498467
GO:0016874	ligase activity	3/524	167/18639	0.0179640718562874	0.638993006353705	0.852240086742823	0.908651794560409
GO:0008173	RNA methyltransferase activity	1/524	67/18639	0.0149253731343284	0.530904637119745	0.852510837001757	0.908651794560409
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1/524	67/18639	0.0149253731343284	0.530904637119745	0.852510837001757	0.908651794560409
GO:0042054	histone methyltransferase activity	1/524	67/18639	0.0149253731343284	0.530904637119745	0.852510837001757	0.908651794560409
GO:0140223	general transcription initiation factor activity	1/524	68/18639	0.0147058823529412	0.523097215985631	0.856672172421264	0.911975004502052
GO:0002039	p53 binding	1/524	69/18639	0.0144927536231884	0.515516096913375	0.860716315528865	0.91345536489592
GO:0016279	protein-lysine N-methyltransferase activity	1/524	69/18639	0.0144927536231884	0.515516096913375	0.860716315528865	0.91345536489592
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/524	122/18639	0.0163934426229508	0.583124765361031	0.861198192991119	0.91345536489592
GO:0016278	lysine N-methyltransferase activity	1/524	70/18639	0.0142857142857143	0.508151581243184	0.864646560583408	0.914892365556778
GO:0016782	transferase activity, transferring sulphur-containing groups	1/524	70/18639	0.0142857142857143	0.508151581243184	0.864646560583408	0.914892365556778
GO:0061630	ubiquitin protein ligase activity	7/524	353/18639	0.0198300283286119	0.705366217589689	0.87100907421101	0.920510194510789
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/524	73/18639	0.0136986301369863	0.487268639548259	0.875785479044949	0.92444022788078
GO:0003684	damaged DNA binding	1/524	74/18639	0.0135135135135135	0.480683928203012	0.879291264296508	0.925904295174877
GO:0035064	methylated histone binding	1/524	74/18639	0.0135135135135135	0.480683928203012	0.879291264296508	0.925904295174877
GO:0051536	iron-sulfur cluster binding	1/524	76/18639	0.0131578947368421	0.468034351145038	0.886009324416586	0.93073575665877
GO:0140034	methylation-dependent protein binding	1/524	76/18639	0.0131578947368421	0.468034351145038	0.886009324416586	0.93073575665877
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	2/524	132/18639	0.0151515151515152	0.538948646773074	0.889130486815424	0.931875856135894
GO:0051540	metal cluster binding	1/524	77/18639	0.012987012987013	0.461955982948349	0.889227075534709	0.931875856135894
GO:0016835	carbon-oxygen lyase activity	1/524	79/18639	0.0126582278481013	0.450260894772442	0.895393138974137	0.937213896363348
GO:0000049	tRNA binding	1/524	80/18639	0.0125	0.444632633587786	0.898346479231548	0.93918041010571
GO:0061659	ubiquitin-like protein ligase activity	7/524	372/18639	0.0188172043010753	0.669339448411721	0.901789249061026	0.941653289939471
GO:0005254	chloride channel activity	1/524	83/18639	0.0120481927710843	0.428561574542445	0.906716440429897	0.944541321735078
GO:0030165	PDZ domain binding	1/524	83/18639	0.0120481927710843	0.428561574542445	0.906716440429897	0.944541321735078
GO:0015293	symporter activity	2/524	146/18639	0.0136986301369863	0.487268639548259	0.919556914778022	0.956777075614275
GO:0015085	calcium ion transmembrane transporter activity	2/524	147/18639	0.0136054421768707	0.483953886898271	0.921399191552535	0.957553975525465
GO:0008276	protein methyltransferase activity	1/524	95/18639	0.0105263157894737	0.374427480916031	0.933858411480268	0.96934946749852
GO:0016407	acetyltransferase activity	1/524	96/18639	0.0104166666666667	0.370527194656489	0.935727382165359	0.970137285898605
GO:0008170	N-methyltransferase activity	1/524	98/18639	0.0102040816326531	0.362965415173703	0.939308666202509	0.971545294983423
GO:0030527	structural constituent of chromatin	1/524	98/18639	0.0102040816326531	0.362965415173703	0.939308666202509	0.971545294983423
GO:0005253	monoatomic anion channel activity	1/524	103/18639	0.00970873786407767	0.345345734825465	0.947414441400049	0.978702252879931
GO:0015103	inorganic anion transmembrane transporter activity	2/524	165/18639	0.0121212121212121	0.431158917418459	0.948467743923686	0.978702252879931
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	2/524	167/18639	0.0119760479041916	0.425995337569137	0.950856843981492	0.980010473631868
GO:0003735	structural constituent of ribosome	2/524	175/18639	0.0114285714285714	0.406521264994547	0.959397559988377	0.987648371531027
GO:0019787	ubiquitin-like protein transferase activity	8/524	479/18639	0.0167014613778706	0.594081180576583	0.961628355044547	0.988780214481099
GO:0015108	chloride transmembrane transporter activity	1/524	121/18639	0.00826446280991736	0.29397198914895	0.968624644635257	0.992495159734473
GO:0008528	G protein-coupled peptide receptor activity	1/524	122/18639	0.00819672131147541	0.291562382680516	0.969512466549672	0.992495159734473
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	1/524	122/18639	0.00819672131147541	0.291562382680516	0.969512466549672	0.992495159734473
GO:0016755	aminoacyltransferase activity	8/524	496/18639	0.0161290322580645	0.573719527210047	0.970722916372418	0.992495159734473
GO:0004842	ubiquitin-protein transferase activity	7/524	449/18639	0.0155902004454343	0.554552950577194	0.970919178001115	0.992495159734473
GO:0001653	peptide receptor activity	1/524	128/18639	0.0078125	0.277895395992366	0.974336861806293	0.993797064335619
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1/524	130/18639	0.00769230769230769	0.273620082207868	0.975769253907812	0.993797064335619
GO:0005262	calcium channel activity	1/524	131/18639	0.00763358778625954	0.271531379290251	0.976455239695932	0.993797064335619
GO:0016779	nucleotidyltransferase activity	1/524	136/18639	0.00735294117647059	0.261548607992815	0.979605106087234	0.993797064335619
GO:0099094	ligand-gated monoatomic cation channel activity	1/524	136/18639	0.00735294117647059	0.261548607992815	0.979605106087234	0.993797064335619
GO:0008168	methyltransferase activity	2/524	204/18639	0.00980392156862745	0.348731477323754	0.979925363768708	0.993797064335619
GO:0140101	catalytic activity, acting on a tRNA	1/524	139/18639	0.00719424460431655	0.255903674007359	0.981289320962974	0.993797064335619
GO:0140767	enzyme-substrate adaptor activity	1/524	139/18639	0.00719424460431655	0.255903674007359	0.981289320962974	0.993797064335619
GO:0016741	transferase activity, transferring one-carbon groups	2/524	215/18639	0.00930232558139535	0.330889401739748	0.984700007907847	0.996096998740114
GO:0008509	monoatomic anion transmembrane transporter activity	1/524	149/18639	0.00671140939597315	0.238728930785389	0.985963072573816	0.996194415131349
GO:0005261	monoatomic cation channel activity	4/524	341/18639	0.0117302052785924	0.41725056524367	0.987536115485608	0.996194415131349
GO:0046873	metal ion transmembrane transporter activity	6/524	450/18639	0.0133333333333333	0.474274809160305	0.98821574132595	0.996194415131349
GO:0045182	translation regulator activity	4/524	356/18639	0.0112359550561798	0.399669783000257	0.990929578027469	0.997779321654387
GO:0015276	ligand-gated monoatomic ion channel activity	1/524	186/18639	0.00537634408602151	0.191239842403349	0.995159935928949	0.999189480367572
GO:0022834	ligand-gated channel activity	1/524	188/18639	0.00531914893617021	0.189205375994803	0.995430921771643	0.999189480367572
GO:0005216	monoatomic ion channel activity	5/524	448/18639	0.0111607142857143	0.396993422846238	0.995759768192397	0.999189480367572
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	1/524	229/18639	0.00436681222707424	0.155330177672589	0.99859957553215	0.999893479195957
GO:0030371	translation repressor activity	2/524	329/18639	0.0060790273556231	0.216234715422632	0.999172364890263	0.999893479195957
GO:0022836	gated channel activity	1/524	318/18639	0.00314465408805031	0.111857266311393	0.999893479195957	0.999893479195957