ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0038024 cargo receptor activity 13/696 65/18639 0.2 5.35603448275862 6.71831871606978e-07 0.000657051570431625 GO:1990841 promoter-specific chromatin binding 12/696 68/18639 0.176470588235294 4.72591277890467 7.1468595128715e-06 0.00258687006358472 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 31/696 349/18639 0.0888252148997135 2.37875456970655 7.93518424412492e-06 0.00258687006358472 GO:0042605 peptide antigen binding 9/696 45/18639 0.2 5.35603448275862 3.5545917697527e-05 0.00752057517619934 GO:0140297 DNA-binding transcription factor binding 37/696 488/18639 0.0758196721311475 2.03046389202939 3.84487483445774e-05 0.00752057517619934 GO:0008135 translation factor activity, RNA binding 12/696 83/18639 0.144578313253012 3.87183215621105 5.70286055589941e-05 0.00898498118782003 GO:0180051 translation factor activity 12/696 84/18639 0.142857142857143 3.82573891625616 6.43096813034154e-05 0.00898498118782003 GO:0048029 monosaccharide binding 11/696 74/18639 0.148648648648649 3.98083643988816 8.91953076526607e-05 0.0109041263605378 GO:0019210 kinase inhibitor activity 12/696 90/18639 0.133333333333333 3.57068965517241 0.000127148789973233 0.0138168351770913 GO:0050840 extracellular matrix binding 10/696 67/18639 0.149253731343284 3.99704065877509 0.000178936405181705 0.0160166972325657 GO:0031625 ubiquitin protein ligase binding 25/696 302/18639 0.0827814569536424 2.21690168988354 0.000180146901388776 0.0160166972325657 GO:0001216 DNA-binding transcription activator activity 35/696 491/18639 0.0712830957230143 1.90897359365124 0.000206791800333842 0.0168535317272081 GO:0004860 protein kinase inhibitor activity 11/696 84/18639 0.130952380952381 3.50692733990148 0.000282889599087604 0.0199911669235266 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 34/696 484/18639 0.0702479338842975 1.88125178113423 0.000331630452145337 0.0199911669235266 GO:0031720 haptoglobin binding 4/696 10/18639 0.4 10.7120689655172 0.000338079798925659 0.0199911669235266 GO:0005178 integrin binding 16/696 161/18639 0.0993788819875776 2.66138359391733 0.000354972926793869 0.0199911669235266 GO:0043394 proteoglycan binding 7/696 37/18639 0.189189189189189 5.06651910531221 0.000380188767511678 0.0199911669235266 GO:0005044 scavenger receptor activity 6/696 27/18639 0.222222222222222 5.95114942528736 0.000401050943991877 0.0199911669235266 GO:0003746 translation elongation factor activity 5/696 18/18639 0.277777777777778 7.4389367816092 0.000408817319499521 0.0199911669235266 GO:0030228 lipoprotein particle receptor activity 5/696 18/18639 0.277777777777778 7.4389367816092 0.000408817319499521 0.0199911669235266 GO:0044389 ubiquitin-like protein ligase binding 25/696 322/18639 0.077639751552795 2.07920593274791 0.000474873072812377 0.0221155173909764 GO:0019887 protein kinase regulator activity 21/696 255/18639 0.0823529411764706 2.20542596348884 0.000616666089287232 0.027413610696496 GO:0001968 fibronectin binding 6/696 30/18639 0.2 5.35603448275862 0.000731360550480102 0.0293647447065543 GO:0031543 peptidyl-proline dioxygenase activity 4/696 12/18639 0.333333333333333 8.92672413793103 0.000750632533398628 0.0293647447065543 GO:0097677 STAT family protein binding 4/696 12/18639 0.333333333333333 8.92672413793103 0.000750632533398628 0.0293647447065543 GO:0045296 cadherin binding 25/696 334/18639 0.0748502994011976 2.00450392318811 0.000807698228818275 0.0303818795301643 GO:0004857 enzyme inhibitor activity 29/696 416/18639 0.0697115384615385 1.86688701923077 0.000998499032062838 0.0361678538280539 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 4/696 13/18639 0.307692307692308 8.24005305039788 0.00105236176078437 0.0367574929302541 GO:0097110 scaffold protein binding 9/696 70/18639 0.128571428571429 3.44316502463054 0.00113806614627236 0.0381684380288104 GO:0019207 kinase regulator activity 22/696 287/18639 0.0766550522648084 2.05283551603989 0.00119594016172233 0.0381684380288104 GO:0140311 protein sequestering activity 6/696 33/18639 0.181818181818182 4.86912225705329 0.00124048475427215 0.0381684380288104 GO:0031072 heat shock protein binding 13/696 131/18639 0.099236641221374 2.65757436167412 0.00124886504797744 0.0381684380288104 GO:0005518 collagen binding 9/696 72/18639 0.125 3.34752155172414 0.00139435041166558 0.0399593144205147 GO:0005161 platelet-derived growth factor receptor binding 4/696 14/18639 0.285714285714286 7.65147783251232 0.0014300368146401 0.0399593144205147 GO:0005344 oxygen carrier activity 4/696 14/18639 0.285714285714286 7.65147783251232 0.0014300368146401 0.0399593144205147 GO:0005201 extracellular matrix structural constituent 15/696 168/18639 0.0892857142857143 2.3910868226601 0.00161051721395788 0.0437523843125224 GO:0048027 mRNA 5'-UTR binding 5/696 24/18639 0.208333333333333 5.5792025862069 0.00168444656859843 0.0445240201105207 GO:0005041 low-density lipoprotein particle receptor activity 4/696 15/18639 0.266666666666667 7.14137931034483 0.00189285489576822 0.0479787942327784 GO:0005539 glycosaminoglycan binding 19/696 242/18639 0.0785123966942149 2.10257552009119 0.00191326480069362 0.0479787942327784 GO:0030246 carbohydrate binding 21/696 280/18639 0.075 2.00851293103448 0.00199714407744416 0.0484484552587411 GO:0008201 heparin binding 15/696 172/18639 0.0872093023255814 2.33548015236568 0.00203107021023352 0.0484484552587411 GO:0008157 protein phosphatase 1 binding 5/696 26/18639 0.192307692307692 5.15003315649867 0.00245106314870414 0.0570747561769678 GO:0008083 growth factor activity 14/696 162/18639 0.0864197530864197 2.31433588761175 0.00306693911002363 0.0690777927822055 GO:0030169 low-density lipoprotein particle binding 4/696 17/18639 0.235294117647059 6.30121703853955 0.00310997845580276 0.0690777927822055 GO:0001618 virus receptor activity 9/696 81/18639 0.111111111111111 2.97557471264368 0.00317842604826099 0.0690777927822055 GO:0140272 exogenous protein binding 9/696 82/18639 0.109756097560976 2.93928721614802 0.00345498358660897 0.0734559553848604 GO:0004725 protein tyrosine phosphatase activity 10/696 98/18639 0.102040816326531 2.73267065446868 0.00359930819487382 0.0736010406750628 GO:0003712 transcription coregulator activity 31/696 495/18639 0.0626262626262626 1.6771421107628 0.00361232101472701 0.0736010406750628 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 8/696 68/18639 0.117647058823529 3.15060851926978 0.00372231136870325 0.0742942962977913 GO:0050811 GABA receptor binding 4/696 18/18639 0.222222222222222 5.95114942528736 0.00388173878046084 0.0759268105458139 GO:0140313 molecular sequestering activity 7/696 55/18639 0.127272727272727 3.4083855799373 0.00419841757193802 0.0803138515161588 GO:0042056 chemoattractant activity 6/696 42/18639 0.142857142857143 3.82573891625616 0.00442338201532582 0.0803138515161588 GO:0043175 RNA polymerase core enzyme binding 6/696 42/18639 0.142857142857143 3.82573891625616 0.00442338201532582 0.0803138515161588 GO:0051087 protein-folding chaperone binding 12/696 134/18639 0.0895522388059701 2.39822439526505 0.00443450713892901 0.0803138515161588 GO:0016209 antioxidant activity 9/696 86/18639 0.104651162790698 2.80257618283881 0.00475515180122688 0.0845552447563615 GO:0008190 eukaryotic initiation factor 4E binding 3/696 10/18639 0.3 8.03405172413793 0.00511023348508526 0.0857221765190143 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 3/696 10/18639 0.3 8.03405172413793 0.00511023348508526 0.0857221765190143 GO:0004601 peroxidase activity 7/696 57/18639 0.12280701754386 3.28879310344828 0.00513108767087722 0.0857221765190143 GO:0005506 iron ion binding 13/696 154/18639 0.0844155844155844 2.26066390506046 0.0051713787470571 0.0857221765190143 GO:0051082 unfolded protein binding 11/696 121/18639 0.0909090909090909 2.43456112852665 0.00563624947901652 0.0918708665079692 GO:0031418 L-ascorbic acid binding 4/696 20/18639 0.2 5.35603448275862 0.00579297061897752 0.0924906212556018 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 9/696 89/18639 0.101123595505618 2.70810732274312 0.0059579848048087 0.0924906212556018 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 9/696 89/18639 0.101123595505618 2.70810732274312 0.0059579848048087 0.0924906212556018 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 7/696 59/18639 0.11864406779661 3.17730859146698 0.00621128355786503 0.0931266126696682 GO:0070063 RNA polymerase binding 7/696 59/18639 0.11864406779661 3.17730859146698 0.00621128355786503 0.0931266126696682 GO:0008013 beta-catenin binding 10/696 106/18639 0.0943396226415094 2.5264313597918 0.00628461803292239 0.0931266126696682 GO:0140793 histone H2AXY142 phosphatase activity 9/696 90/18639 0.1 2.67801724137931 0.00640702076138586 0.0935233776811249 GO:0044183 protein folding chaperone 8/696 75/18639 0.106666666666667 2.85655172413793 0.00677202960968834 0.0941251919734822 GO:0001851 complement component C3b binding 3/696 11/18639 0.272727272727273 7.30368338557994 0.00683321945819758 0.0941251919734822 GO:0005536 D-glucose binding 3/696 11/18639 0.272727272727273 7.30368338557994 0.00683321945819758 0.0941251919734822 GO:0097493 structural molecule activity conferring elasticity 3/696 11/18639 0.272727272727273 7.30368338557994 0.00683321945819758 0.0941251919734822 GO:0030291 protein serine/threonine kinase inhibitor activity 6/696 46/18639 0.130434782608696 3.49306596701649 0.00696689930965574 0.0946337156228238 GO:0019903 protein phosphatase binding 12/696 144/18639 0.0833333333333333 2.23168103448276 0.00780606717493369 0.104579913658701 GO:0003724 RNA helicase activity 8/696 77/18639 0.103896103896104 2.78235557545902 0.00791779804094672 0.104643330865485 GO:0019825 oxygen binding 5/696 34/18639 0.147058823529412 3.93826064908722 0.00811323195396194 0.105796544679664 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 6/696 48/18639 0.125 3.34752155172414 0.0085736776483864 0.109693822374705 GO:0045295 gamma-catenin binding 3/696 12/18639 0.25 6.69504310344828 0.00886074843313056 0.109693822374705 GO:0070008 serine-type exopeptidase activity 3/696 12/18639 0.25 6.69504310344828 0.00886074843313056 0.109693822374705 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/696 12/18639 0.25 6.69504310344828 0.00886074843313056 0.109693822374705 GO:0008186 ATP-dependent activity, acting on RNA 8/696 79/18639 0.10126582278481 2.71191619380183 0.00920328486352721 0.11251015745662 GO:0003714 transcription corepressor activity 15/696 204/18639 0.0735294117647059 1.96913032454361 0.00980342808283451 0.11725451014584 GO:0042578 phosphoric ester hydrolase activity 23/696 363/18639 0.0633608815426997 1.69681533200342 0.00983115524740176 0.11725451014584 GO:0000993 RNA polymerase II complex binding 5/696 36/18639 0.138888888888889 3.7194683908046 0.0103418050976343 0.121858860066101 GO:0035035 histone acetyltransferase binding 4/696 24/18639 0.166666666666667 4.46336206896552 0.0112927839517392 0.131480270295249 GO:0016830 carbon-carbon lyase activity 6/696 51/18639 0.117647058823529 3.15060851926978 0.0114575388428723 0.131829093980342 GO:0042805 actinin binding 5/696 37/18639 0.135135135135135 3.61894221808015 0.0115991840784113 0.131907000333561 GO:0140789 histone phosphatase activity 11/696 136/18639 0.0808823529411765 2.16604335699797 0.0130730893607674 0.14695955626242 GO:0016860 intramolecular oxidoreductase activity 6/696 53/18639 0.113207547169811 3.03171763175016 0.0137232247503154 0.15080127871695 GO:0140296 general transcription initiation factor binding 6/696 53/18639 0.113207547169811 3.03171763175016 0.0137232247503154 0.15080127871695 GO:0004721 phosphoprotein phosphatase activity 13/696 175/18639 0.0742857142857143 1.9893842364532 0.0143658909239477 0.156109348040232 GO:0005125 cytokine activity 16/696 234/18639 0.0683760683760684 1.83112290008842 0.0149089777399726 0.157561903559783 GO:0017069 snRNA binding 6/696 54/18639 0.111111111111111 2.97557471264368 0.0149657217069389 0.157561903559783 GO:0008198 ferrous iron binding 4/696 26/18639 0.153846153846154 4.12002652519894 0.0149828803998567 0.157561903559783 GO:0097718 disordered domain specific binding 4/696 28/18639 0.142857142857143 3.82573891625616 0.019354247013666 0.200234358032699 GO:0008307 structural constituent of muscle 5/696 42/18639 0.119047619047619 3.1881157635468 0.0194501677025628 0.200234358032699 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 6/696 58/18639 0.103448275862069 2.77036266349584 0.0207153065456876 0.208861544347242 GO:0061980 regulatory RNA binding 6/696 58/18639 0.103448275862069 2.77036266349584 0.0207153065456876 0.208861544347242 GO:0043178 alcohol binding 8/696 92/18639 0.0869565217391304 2.32871064467766 0.0216286721601377 0.211144332056821 GO:0003725 double-stranded RNA binding 7/696 75/18639 0.0933333333333333 2.49948275862069 0.0217533452400046 0.211144332056821 GO:0004629 phospholipase C activity 4/696 29/18639 0.137931034482759 3.69381688466112 0.021805294005868 0.211144332056821 GO:0051861 glycolipid binding 4/696 29/18639 0.137931034482759 3.69381688466112 0.021805294005868 0.211144332056821 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 3/696 17/18639 0.176470588235294 4.72591277890467 0.0238483922592408 0.21609894156939 GO:0008429 phosphatidylethanolamine binding 3/696 17/18639 0.176470588235294 4.72591277890467 0.0238483922592408 0.21609894156939 GO:0019198 transmembrane receptor protein phosphatase activity 3/696 17/18639 0.176470588235294 4.72591277890467 0.0238483922592408 0.21609894156939 GO:0038191 neuropilin binding 3/696 17/18639 0.176470588235294 4.72591277890467 0.0238483922592408 0.21609894156939 GO:0070403 NAD+ binding 3/696 17/18639 0.176470588235294 4.72591277890467 0.0238483922592408 0.21609894156939 GO:0001098 basal transcription machinery binding 6/696 60/18639 0.1 2.67801724137931 0.0240846468620281 0.21609894156939 GO:0001099 basal RNA polymerase II transcription machinery binding 6/696 60/18639 0.1 2.67801724137931 0.0240846468620281 0.21609894156939 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 6/696 60/18639 0.1 2.67801724137931 0.0240846468620281 0.21609894156939 GO:0008106 alcohol dehydrogenase (NADP+) activity 4/696 30/18639 0.133333333333333 3.57068965517241 0.0244374974121881 0.21727156790109 GO:0042277 peptide binding 16/696 249/18639 0.0642570281124498 1.72081429164936 0.0250756872902064 0.218964483659123 GO:0140104 molecular carrier activity 16/696 249/18639 0.0642570281124498 1.72081429164936 0.0250756872902064 0.218964483659123 GO:0019902 phosphatase binding 13/696 190/18639 0.068421052631579 1.8323275862069 0.0263364252255006 0.227938264341058 GO:0016854 racemase and epimerase activity 3/696 18/18639 0.166666666666667 4.46336206896552 0.0278417229549968 0.232728248290486 GO:0034185 apolipoprotein binding 3/696 18/18639 0.166666666666667 4.46336206896552 0.0278417229549968 0.232728248290486 GO:0070628 proteasome binding 3/696 18/18639 0.166666666666667 4.46336206896552 0.0278417229549968 0.232728248290486 GO:1990381 ubiquitin-specific protease binding 3/696 18/18639 0.166666666666667 4.46336206896552 0.0278417229549968 0.232728248290486 GO:0005126 cytokine receptor binding 17/696 275/18639 0.0618181818181818 1.65550156739812 0.0296209979557551 0.245502847463801 GO:0071813 lipoprotein particle binding 4/696 32/18639 0.125 3.34752155172414 0.0302550889414834 0.24657897487309 GO:0071814 protein-lipid complex binding 4/696 32/18639 0.125 3.34752155172414 0.0302550889414834 0.24657897487309 GO:0004386 helicase activity 11/696 155/18639 0.0709677419354839 1.90052836484983 0.0310589096294248 0.249641226850225 GO:0003713 transcription coactivator activity 16/696 256/18639 0.0625 1.67376077586207 0.0313003165652915 0.249641226850225 GO:0002020 protease binding 10/696 136/18639 0.0735294117647059 1.96913032454361 0.0313965960149056 0.249641226850225 GO:0097001 ceramide binding 3/696 19/18639 0.157894736842105 4.22844827586207 0.032167027009704 0.251819765020635 GO:0001217 DNA-binding transcription repressor activity 17/696 278/18639 0.0611510791366906 1.63763644257008 0.0323707689404932 0.251819765020635 GO:0038187 pattern recognition receptor activity 5/696 48/18639 0.104166666666667 2.78960129310345 0.0326731470879201 0.251819765020635 GO:0022853 active monoatomic ion transmembrane transporter activity 9/696 118/18639 0.076271186440678 2.04255552308591 0.0327005216335589 0.251819765020635 GO:0071889 14-3-3 protein binding 4/696 33/18639 0.121212121212121 3.24608150470219 0.0334441045827548 0.253552978929722 GO:0140416 transcription regulator inhibitor activity 4/696 33/18639 0.121212121212121 3.24608150470219 0.0334441045827548 0.253552978929722 GO:0001222 transcription corepressor binding 5/696 49/18639 0.102040816326531 2.73267065446868 0.0353099343344841 0.263611570833018 GO:0060590 ATPase regulator activity 5/696 49/18639 0.102040816326531 2.73267065446868 0.0353099343344841 0.263611570833018 GO:0042288 MHC class I protein binding 3/696 20/18639 0.15 4.01702586206896 0.0368212722551264 0.27076300806563 GO:0016831 carboxy-lyase activity 4/696 34/18639 0.117647058823529 3.15060851926978 0.0368215542665939 0.27076300806563 GO:0016853 isomerase activity 12/696 180/18639 0.0666666666666667 1.78534482758621 0.0379178410225323 0.276743645671915 GO:0003743 translation initiation factor activity 5/696 51/18639 0.0980392156862745 2.62550709939148 0.0409675147359578 0.294604628027697 GO:0030544 Hsp70 protein binding 5/696 51/18639 0.0980392156862745 2.62550709939148 0.0409675147359578 0.294604628027697 GO:0001846 opsonin binding 3/696 21/18639 0.142857142857143 3.82573891625616 0.0418001767355818 0.298398341951818 GO:0008081 phosphoric diester hydrolase activity 7/696 87/18639 0.0804597701149425 2.15472651605232 0.0439470939331539 0.310594920366403 GO:0004033 aldo-keto reductase (NADPH) activity 4/696 36/18639 0.111111111111111 2.97557471264368 0.0441438588250818 0.310594920366403 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 16/696 268/18639 0.0597014925373134 1.59881626351004 0.0445094679710521 0.310930426254921 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/696 22/18639 0.136363636363636 3.65184169278997 0.0470983435324435 0.323075871146128 GO:0140517 protein-RNA adaptor activity 3/696 22/18639 0.136363636363636 3.65184169278997 0.0470983435324435 0.323075871146128 GO:0015399 primary active transmembrane transporter activity 11/696 166/18639 0.0662650602409639 1.7745897382634 0.0472391099937591 0.323075871146128 GO:0023023 MHC protein complex binding 4/696 37/18639 0.108108108108108 2.89515377446412 0.0480886678852843 0.32582366555083 GO:0031406 carboxylic acid binding 12/696 187/18639 0.0641711229946524 1.71851373778351 0.0483071896777815 0.32582366555083 GO:0140597 protein carrier chaperone 12/696 188/18639 0.0638297872340425 1.70937270726339 0.0499360187731542 0.327705822682356 GO:0015485 cholesterol binding 5/696 54/18639 0.0925925925925926 2.47964559386973 0.0504263698091849 0.327705822682356 GO:0016791 phosphatase activity 16/696 273/18639 0.0586080586080586 1.5695339143615 0.0510411854136647 0.327705822682356 GO:0004090 carbonyl reductase (NADPH) activity 2/696 10/18639 0.2 5.35603448275862 0.051360241688413 0.327705822682356 GO:0004955 prostaglandin receptor activity 2/696 10/18639 0.2 5.35603448275862 0.051360241688413 0.327705822682356 GO:0005381 iron ion transmembrane transporter activity 2/696 10/18639 0.2 5.35603448275862 0.051360241688413 0.327705822682356 GO:0008401 retinoic acid 4-hydroxylase activity 2/696 10/18639 0.2 5.35603448275862 0.051360241688413 0.327705822682356 GO:0099122 RNA polymerase II C-terminal domain binding 2/696 10/18639 0.2 5.35603448275862 0.051360241688413 0.327705822682356 GO:0043177 organic acid binding 12/696 189/18639 0.0634920634920635 1.70032840722496 0.0516019393589804 0.327705822682356 GO:0070577 lysine-acetylated histone binding 3/696 23/18639 0.130434782608696 3.49306596701649 0.0527093859041277 0.329162211736088 GO:1901681 sulfur compound binding 16/696 275/18639 0.0581818181818182 1.55811912225705 0.0538326197862972 0.329162211736088 GO:0000510 H3-H4 histone complex chaperone activity 10/696 151/18639 0.0662251655629139 1.77352135190683 0.0569293769529113 0.329162211736088 GO:0140584 chromatin extrusion motor activity 10/696 151/18639 0.0662251655629139 1.77352135190683 0.0569293769529113 0.329162211736088 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 10/696 151/18639 0.0662251655629139 1.77352135190683 0.0569293769529113 0.329162211736088 GO:0140849 ATP-dependent H2AZ histone chaperone activity 10/696 151/18639 0.0662251655629139 1.77352135190683 0.0569293769529113 0.329162211736088 GO:0005540 hyaluronic acid binding 3/696 24/18639 0.125 3.34752155172414 0.0586260433258975 0.329162211736088 GO:0015149 hexose transmembrane transporter activity 3/696 24/18639 0.125 3.34752155172414 0.0586260433258975 0.329162211736088 GO:0030215 semaphorin receptor binding 3/696 24/18639 0.125 3.34752155172414 0.0586260433258975 0.329162211736088 GO:0055056 D-glucose transmembrane transporter activity 3/696 24/18639 0.125 3.34752155172414 0.0586260433258975 0.329162211736088 GO:0060229 lipase activator activity 3/696 24/18639 0.125 3.34752155172414 0.0586260433258975 0.329162211736088 GO:0140033 acetylation-dependent protein binding 3/696 24/18639 0.125 3.34752155172414 0.0586260433258975 0.329162211736088 GO:0015616 DNA translocase activity 10/696 152/18639 0.0657894736842105 1.76185344827586 0.0590062540519866 0.329162211736088 GO:0140674 ATP-dependent histone chaperone activity 10/696 152/18639 0.0657894736842105 1.76185344827586 0.0590062540519866 0.329162211736088 GO:0051213 dioxygenase activity 7/696 93/18639 0.0752688172043011 2.01571190211346 0.0591061469094571 0.329162211736088 GO:0015144 carbohydrate transmembrane transporter activity 4/696 40/18639 0.1 2.67801724137931 0.0610487842305002 0.329162211736088 GO:0140662 ATP-dependent protein folding chaperone 4/696 40/18639 0.1 2.67801724137931 0.0610487842305002 0.329162211736088 GO:0061775 cohesin loader activity 10/696 153/18639 0.065359477124183 1.75033806626099 0.0611319263216243 0.329162211736088 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 2/696 11/18639 0.181818181818182 4.86912225705329 0.0612551355173498 0.329162211736088 GO:0004954 prostanoid receptor activity 2/696 11/18639 0.181818181818182 4.86912225705329 0.0612551355173498 0.329162211736088 GO:0008432 JUN kinase binding 2/696 11/18639 0.181818181818182 4.86912225705329 0.0612551355173498 0.329162211736088 GO:0008503 benzodiazepine receptor activity 2/696 11/18639 0.181818181818182 4.86912225705329 0.0612551355173498 0.329162211736088 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/696 11/18639 0.181818181818182 4.86912225705329 0.0612551355173498 0.329162211736088 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/696 11/18639 0.181818181818182 4.86912225705329 0.0612551355173498 0.329162211736088 GO:0019215 intermediate filament binding 2/696 11/18639 0.181818181818182 4.86912225705329 0.0612551355173498 0.329162211736088 GO:0042608 T cell receptor binding 2/696 11/18639 0.181818181818182 4.86912225705329 0.0612551355173498 0.329162211736088 GO:0043522 leucine zipper domain binding 2/696 11/18639 0.181818181818182 4.86912225705329 0.0612551355173498 0.329162211736088 GO:0140031 phosphorylation-dependent protein binding 2/696 11/18639 0.181818181818182 4.86912225705329 0.0612551355173498 0.329162211736088 GO:0004867 serine-type endopeptidase inhibitor activity 7/696 95/18639 0.0736842105263158 1.97327586206897 0.064792799059609 0.33911124398031 GO:0001848 complement binding 3/696 25/18639 0.12 3.21362068965517 0.0648402889819202 0.33911124398031 GO:0005537 D-mannose binding 3/696 25/18639 0.12 3.21362068965517 0.0648402889819202 0.33911124398031 GO:0008483 transaminase activity 3/696 25/18639 0.12 3.21362068965517 0.0648402889819202 0.33911124398031 GO:0015296 monoatomic anion:monoatomic cation symporter activity 3/696 25/18639 0.12 3.21362068965517 0.0648402889819202 0.33911124398031 GO:0008137 NADH dehydrogenase (ubiquinone) activity 4/696 41/18639 0.0975609756097561 2.61269974768713 0.0657393268884398 0.34198437072816 GO:0001221 transcription coregulator binding 8/696 115/18639 0.0695652173913043 1.86296851574213 0.0662577243567575 0.342857430798459 GO:0019838 growth factor binding 9/696 136/18639 0.0661764705882353 1.77221729208925 0.0688147805278261 0.349034152485778 GO:0044325 transmembrane transporter binding 9/696 136/18639 0.0661764705882353 1.77221729208925 0.0688147805278261 0.349034152485778 GO:0009055 electron transfer activity 8/696 116/18639 0.0689655172413793 1.84690844233056 0.0689629104734212 0.349034152485778 GO:0035198 miRNA binding 4/696 42/18639 0.0952380952380952 2.55049261083744 0.0706118699606374 0.349034152485778 GO:0004435 phosphatidylinositol phospholipase C activity 3/696 26/18639 0.115384615384615 3.0900198938992 0.0713434292317546 0.349034152485778 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/696 26/18639 0.115384615384615 3.0900198938992 0.0713434292317546 0.349034152485778 GO:0015145 monosaccharide transmembrane transporter activity 3/696 26/18639 0.115384615384615 3.0900198938992 0.0713434292317546 0.349034152485778 GO:0097602 cullin family protein binding 3/696 26/18639 0.115384615384615 3.0900198938992 0.0713434292317546 0.349034152485778 GO:0016922 nuclear receptor binding 9/696 137/18639 0.0656934306569343 1.75928139944626 0.071348061185667 0.349034152485778 GO:0004875 complement receptor activity 2/696 12/18639 0.166666666666667 4.46336206896552 0.0717340129341937 0.349034152485778 GO:0015166 polyol transmembrane transporter activity 2/696 12/18639 0.166666666666667 4.46336206896552 0.0717340129341937 0.349034152485778 GO:0017166 vinculin binding 2/696 12/18639 0.166666666666667 4.46336206896552 0.0717340129341937 0.349034152485778 GO:0140658 ATP-dependent chromatin remodeler activity 10/696 158/18639 0.0632911392405063 1.69494762112615 0.0725000594482058 0.35101513930864 GO:0048156 tau protein binding 4/696 43/18639 0.0930232558139535 2.49117882919006 0.0756639684045873 0.359641476852849 GO:0003689 DNA clamp loader activity 10/696 160/18639 0.0625 1.67376077586207 0.0773957390144134 0.359641476852849 GO:0001671 ATPase activator activity 3/696 27/18639 0.111111111111111 2.97557471264368 0.0781261955447321 0.359641476852849 GO:0023026 MHC class II protein complex binding 3/696 27/18639 0.111111111111111 2.97557471264368 0.0781261955447321 0.359641476852849 GO:0035255 ionotropic glutamate receptor binding 3/696 27/18639 0.111111111111111 2.97557471264368 0.0781261955447321 0.359641476852849 GO:0003954 NADH dehydrogenase activity 4/696 44/18639 0.0909090909090909 2.43456112852665 0.0808928739934782 0.359641476852849 GO:0030547 signaling receptor inhibitor activity 4/696 44/18639 0.0909090909090909 2.43456112852665 0.0808928739934782 0.359641476852849 GO:0061134 peptidase regulator activity 13/696 226/18639 0.0575221238938053 1.54045239548367 0.0820273971176144 0.359641476852849 GO:0033192 calmodulin-dependent protein phosphatase activity 6/696 81/18639 0.0740740740740741 1.98371647509579 0.0821117015980541 0.359641476852849 GO:0140791 histone H2AXS140 phosphatase activity 6/696 81/18639 0.0740740740740741 1.98371647509579 0.0821117015980541 0.359641476852849 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 6/696 81/18639 0.0740740740740741 1.98371647509579 0.0821117015980541 0.359641476852849 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 6/696 81/18639 0.0740740740740741 1.98371647509579 0.0821117015980541 0.359641476852849 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 6/696 81/18639 0.0740740740740741 1.98371647509579 0.0821117015980541 0.359641476852849 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 6/696 81/18639 0.0740740740740741 1.98371647509579 0.0821117015980541 0.359641476852849 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 6/696 81/18639 0.0740740740740741 1.98371647509579 0.0821117015980541 0.359641476852849 GO:1990439 MAP kinase serine/threonine phosphatase activity 6/696 81/18639 0.0740740740740741 1.98371647509579 0.0821117015980541 0.359641476852849 GO:0005172 vascular endothelial growth factor receptor binding 2/696 13/18639 0.153846153846154 4.12002652519894 0.0827396035704407 0.359641476852849 GO:0008035 high-density lipoprotein particle binding 2/696 13/18639 0.153846153846154 4.12002652519894 0.0827396035704407 0.359641476852849 GO:0032396 inhibitory MHC class I receptor activity 2/696 13/18639 0.153846153846154 4.12002652519894 0.0827396035704407 0.359641476852849 GO:0035673 oligopeptide transmembrane transporter activity 2/696 13/18639 0.153846153846154 4.12002652519894 0.0827396035704407 0.359641476852849 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/696 13/18639 0.153846153846154 4.12002652519894 0.0827396035704407 0.359641476852849 GO:0097157 pre-mRNA intronic binding 2/696 13/18639 0.153846153846154 4.12002652519894 0.0827396035704407 0.359641476852849 GO:0140666 annealing activity 2/696 13/18639 0.153846153846154 4.12002652519894 0.0827396035704407 0.359641476852849 GO:0008237 metallopeptidase activity 11/696 184/18639 0.0597826086956522 1.60098856821589 0.0845743044961868 0.360627251611922 GO:0020037 heme binding 9/696 142/18639 0.0633802816901408 1.69733487129675 0.0848739960743571 0.360627251611922 GO:0045499 chemorepellent activity 3/696 28/18639 0.107142857142857 2.86930418719212 0.0851788293684601 0.360627251611922 GO:0046625 sphingolipid binding 3/696 28/18639 0.107142857142857 2.86930418719212 0.0851788293684601 0.360627251611922 GO:0051119 sugar transmembrane transporter activity 3/696 28/18639 0.107142857142857 2.86930418719212 0.0851788293684601 0.360627251611922 GO:0051393 alpha-actinin binding 3/696 28/18639 0.107142857142857 2.86930418719212 0.0851788293684601 0.360627251611922 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 6/696 82/18639 0.0731707317073171 1.95952481076535 0.0859546291502782 0.360671161774905 GO:0033549 MAP kinase phosphatase activity 6/696 82/18639 0.0731707317073171 1.95952481076535 0.0859546291502782 0.360671161774905 GO:0046915 transition metal ion transmembrane transporter activity 4/696 45/18639 0.0888888888888889 2.38045977011494 0.0862955540443024 0.360671161774905 GO:0015078 proton transmembrane transporter activity 11/696 185/18639 0.0594594594594595 1.59233457595527 0.0870660373615943 0.362342912934635 GO:0140713 histone chaperone activity 10/696 164/18639 0.0609756097560976 1.63293734230446 0.0877887930535277 0.363802710196399 GO:0001540 amyloid-beta binding 6/696 83/18639 0.072289156626506 1.93591607810553 0.089894928291218 0.369400167516013 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 6/696 83/18639 0.072289156626506 1.93591607810553 0.089894928291218 0.369400167516013 GO:0004722 protein serine/threonine phosphatase activity 7/696 103/18639 0.0679611650485437 1.82001171744225 0.0907382859789969 0.370061410359499 GO:0022804 active transmembrane transporter activity 23/696 457/18639 0.050328227571116 1.3477986116351 0.091294250932804 0.370061410359499 GO:0004180 carboxypeptidase activity 4/696 46/18639 0.0869565217391304 2.32871064467766 0.0918687100318246 0.370061410359499 GO:0004181 metallocarboxypeptidase activity 3/696 29/18639 0.103448275862069 2.77036266349584 0.0924911603718361 0.370061410359499 GO:0017018 myosin phosphatase activity 6/696 84/18639 0.0714285714285714 1.91286945812808 0.0939318994758224 0.370061410359499 GO:0051117 ATPase binding 6/696 84/18639 0.0714285714285714 1.91286945812808 0.0939318994758224 0.370061410359499 GO:0005347 ATP transmembrane transporter activity 2/696 14/18639 0.142857142857143 3.82573891625616 0.0942180891406088 0.370061410359499 GO:0008494 translation activator activity 2/696 14/18639 0.142857142857143 3.82573891625616 0.0942180891406088 0.370061410359499 GO:0042043 neurexin family protein binding 2/696 14/18639 0.142857142857143 3.82573891625616 0.0942180891406088 0.370061410359499 GO:0043176 amine binding 2/696 14/18639 0.142857142857143 3.82573891625616 0.0942180891406088 0.370061410359499 GO:0098847 sequence-specific single stranded DNA binding 2/696 14/18639 0.142857142857143 3.82573891625616 0.0942180891406088 0.370061410359499 GO:0016769 transferase activity, transferring nitrogenous groups 3/696 30/18639 0.1 2.67801724137931 0.100052678478464 0.387793540004753 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/696 30/18639 0.1 2.67801724137931 0.100052678478464 0.387793540004753 GO:0048019 receptor antagonist activity 3/696 30/18639 0.1 2.67801724137931 0.100052678478464 0.387793540004753 GO:0042826 histone deacetylase binding 8/696 127/18639 0.062992125984252 1.68693999456964 0.103125261633952 0.387793540004753 GO:0140693 molecular condensate scaffold activity 4/696 48/18639 0.0833333333333333 2.23168103448276 0.103512036829061 0.387793540004753 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5/696 67/18639 0.0746268656716418 1.99852032938754 0.104854033581902 0.387793540004753 GO:0019888 protein phosphatase regulator activity 7/696 107/18639 0.0654205607476635 1.75197389622946 0.105610228158549 0.387793540004753 GO:0004129 cytochrome-c oxidase activity 2/696 15/18639 0.133333333333333 3.57068965517241 0.106118926091033 0.387793540004753 GO:0004953 icosanoid receptor activity 2/696 15/18639 0.133333333333333 3.57068965517241 0.106118926091033 0.387793540004753 GO:0005523 tropomyosin binding 2/696 15/18639 0.133333333333333 3.57068965517241 0.106118926091033 0.387793540004753 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/696 15/18639 0.133333333333333 3.57068965517241 0.106118926091033 0.387793540004753 GO:0031386 protein tag activity 2/696 15/18639 0.133333333333333 3.57068965517241 0.106118926091033 0.387793540004753 GO:0042809 nuclear vitamin D receptor binding 2/696 15/18639 0.133333333333333 3.57068965517241 0.106118926091033 0.387793540004753 GO:0051371 muscle alpha-actinin binding 2/696 15/18639 0.133333333333333 3.57068965517241 0.106118926091033 0.387793540004753 GO:0140776 protein-containing complex destabilizing activity 2/696 15/18639 0.133333333333333 3.57068965517241 0.106118926091033 0.387793540004753 GO:0141047 molecular tag activity 2/696 15/18639 0.133333333333333 3.57068965517241 0.106118926091033 0.387793540004753 GO:0141050 histone H3K deacetylase activity 2/696 15/18639 0.133333333333333 3.57068965517241 0.106118926091033 0.387793540004753 GO:0141051 histone H4K deacetylase activity 2/696 15/18639 0.133333333333333 3.57068965517241 0.106118926091033 0.387793540004753 GO:0003779 actin binding 22/696 443/18639 0.0496613995485327 1.32994084221997 0.107386906432784 0.387793540004753 GO:0005164 tumor necrosis factor receptor binding 3/696 31/18639 0.0967741935483871 2.59162958843159 0.107852600083122 0.387793540004753 GO:0008327 methyl-CpG binding 3/696 31/18639 0.0967741935483871 2.59162958843159 0.107852600083122 0.387793540004753 GO:0070325 lipoprotein particle receptor binding 3/696 31/18639 0.0967741935483871 2.59162958843159 0.107852600083122 0.387793540004753 GO:0072349 modified amino acid transmembrane transporter activity 3/696 31/18639 0.0967741935483871 2.59162958843159 0.107852600083122 0.387793540004753 GO:0019842 vitamin binding 9/696 150/18639 0.06 1.60681034482759 0.109489381008302 0.39223668361216 GO:0032934 sterol binding 5/696 68/18639 0.0735294117647059 1.96913032454361 0.109909504039608 0.39230472609758 GO:0016651 oxidoreductase activity, acting on NAD(P)H 6/696 88/18639 0.0681818181818182 1.82592084639498 0.111029371251642 0.394860818487658 GO:0008236 serine-type peptidase activity 11/696 194/18639 0.0567010309278351 1.51846338428724 0.111495051258783 0.395080290330036 GO:0140030 modification-dependent protein binding 10/696 173/18639 0.0578034682080925 1.54798684472793 0.114100280993774 0.400657417868434 GO:0003727 single-stranded RNA binding 6/696 89/18639 0.0674157303370786 1.80540488182875 0.115536100452738 0.400657417868434 GO:0032813 tumor necrosis factor receptor superfamily binding 4/696 50/18639 0.08 2.14241379310345 0.115791842991448 0.400657417868434 GO:0031369 translation initiation factor binding 3/696 32/18639 0.09375 2.5106411637931 0.115879928821912 0.400657417868434 GO:0043425 bHLH transcription factor binding 3/696 32/18639 0.09375 2.5106411637931 0.115879928821912 0.400657417868434 GO:0046906 tetrapyrrole binding 9/696 152/18639 0.0592105263157895 1.58566810344828 0.11620756882461 0.400657417868434 GO:0004222 metalloendopeptidase activity 7/696 110/18639 0.0636363636363636 1.70419278996865 0.117571812678428 0.400657417868434 GO:0015562 efflux transmembrane transporter activity 2/696 16/18639 0.125 3.34752155172414 0.118394676650284 0.400657417868434 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/696 16/18639 0.125 3.34752155172414 0.118394676650284 0.400657417868434 GO:0017070 U6 snRNA binding 2/696 16/18639 0.125 3.34752155172414 0.118394676650284 0.400657417868434 GO:0030275 LRR domain binding 2/696 16/18639 0.125 3.34752155172414 0.118394676650284 0.400657417868434 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/696 16/18639 0.125 3.34752155172414 0.118394676650284 0.400657417868434 GO:0097027 ubiquitin-protein transferase activator activity 2/696 16/18639 0.125 3.34752155172414 0.118394676650284 0.400657417868434 GO:0003735 structural constituent of ribosome 10/696 175/18639 0.0571428571428571 1.53029556650246 0.120490887021101 0.406345129333232 GO:0017171 serine hydrolase activity 11/696 198/18639 0.0555555555555556 1.48778735632184 0.123499062691562 0.415058705540713 GO:0030296 protein tyrosine kinase activator activity 3/696 33/18639 0.0909090909090909 2.43456112852665 0.124123511245827 0.415728746569929 GO:0004175 endopeptidase activity 20/696 405/18639 0.0493827160493827 1.32247765006386 0.125033935416307 0.417348767362281 GO:0043021 ribonucleoprotein complex binding 10/696 177/18639 0.0564971751412429 1.51300409117475 0.127075283357751 0.422719820149253 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 4/696 52/18639 0.0769230769230769 2.06001326259947 0.128674012697033 0.422834419962275 GO:0016829 lyase activity 11/696 200/18639 0.055 1.47290948275862 0.129760757883149 0.422834419962275 GO:0140375 immune receptor activity 9/696 156/18639 0.0576923076923077 1.5450099469496 0.130304440245206 0.422834419962275 GO:0005092 GDP-dissociation inhibitor activity 2/696 17/18639 0.117647058823529 3.15060851926978 0.131000847902423 0.422834419962275 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/696 17/18639 0.117647058823529 3.15060851926978 0.131000847902423 0.422834419962275 GO:0032183 SUMO binding 2/696 17/18639 0.117647058823529 3.15060851926978 0.131000847902423 0.422834419962275 GO:0048038 quinone binding 2/696 17/18639 0.117647058823529 3.15060851926978 0.131000847902423 0.422834419962275 GO:0051787 misfolded protein binding 2/696 17/18639 0.117647058823529 3.15060851926978 0.131000847902423 0.422834419962275 GO:1990226 histone methyltransferase binding 2/696 17/18639 0.117647058823529 3.15060851926978 0.131000847902423 0.422834419962275 GO:0090482 vitamin transmembrane transporter activity 3/696 34/18639 0.0882352941176471 2.36295638945233 0.132572087727689 0.426498361176578 GO:0005096 GTPase activator activity 14/696 271/18639 0.0516605166051661 1.38347754167197 0.138625612355341 0.44451097994598 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 10/696 181/18639 0.0552486187845304 1.47956753667365 0.140815156021758 0.450056282971501 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/696 54/18639 0.0740740740740741 1.98371647509579 0.142121866505946 0.451057795748052 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/696 18/18639 0.111111111111111 2.97557471264368 0.143895738520851 0.451057795748052 GO:0017075 syntaxin-1 binding 2/696 18/18639 0.111111111111111 2.97557471264368 0.143895738520851 0.451057795748052 GO:0022851 GABA-gated chloride ion channel activity 2/696 18/18639 0.111111111111111 2.97557471264368 0.143895738520851 0.451057795748052 GO:0032393 MHC class I receptor activity 2/696 18/18639 0.111111111111111 2.97557471264368 0.143895738520851 0.451057795748052 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/696 18/18639 0.111111111111111 2.97557471264368 0.143895738520851 0.451057795748052 GO:0019208 phosphatase regulator activity 7/696 117/18639 0.0598290598290598 1.60223253757737 0.148050461353928 0.461440476717981 GO:0098632 cell-cell adhesion mediator activity 4/696 55/18639 0.0727272727272727 1.94764890282132 0.149045888186493 0.461440476717981 GO:0004866 endopeptidase inhibitor activity 9/696 161/18639 0.0559006211180124 1.4970282715785 0.149127799777632 0.461440476717981 GO:0030295 protein kinase activator activity 8/696 139/18639 0.0575539568345324 1.54130488712478 0.149326692935145 0.461440476717981 GO:0045505 dynein intermediate chain binding 3/696 36/18639 0.0833333333333333 2.23168103448276 0.150038928012595 0.461440476717981 GO:0055106 ubiquitin-protein transferase regulator activity 3/696 36/18639 0.0833333333333333 2.23168103448276 0.150038928012595 0.461440476717981 GO:0061135 endopeptidase regulator activity 10/696 184/18639 0.0543478260869565 1.45544415292354 0.15160773019749 0.464803636781018 GO:0016887 ATP hydrolysis activity 20/696 417/18639 0.0479616306954436 1.28442073927065 0.152298902114993 0.465098328046618 GO:0030695 GTPase regulator activity 23/696 489/18639 0.0470347648261759 1.2595991114872 0.152654972702418 0.465098328046618 GO:0098631 cell adhesion mediator activity 5/696 76/18639 0.0657894736842105 1.76185344827586 0.154340545580423 0.466824943386997 GO:0060589 nucleoside-triphosphatase regulator activity 23/696 490/18639 0.0469387755102041 1.25702850105559 0.154881259821173 0.466824943386997 GO:0004890 GABA-A receptor activity 2/696 19/18639 0.105263157894737 2.81896551724138 0.15704029281628 0.466824943386997 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/696 19/18639 0.105263157894737 2.81896551724138 0.15704029281628 0.466824943386997 GO:0008301 DNA binding, bending 2/696 19/18639 0.105263157894737 2.81896551724138 0.15704029281628 0.466824943386997 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/696 19/18639 0.105263157894737 2.81896551724138 0.15704029281628 0.466824943386997 GO:0042577 lipid phosphatase activity 2/696 19/18639 0.105263157894737 2.81896551724138 0.15704029281628 0.466824943386997 GO:0046624 sphingolipid transporter activity 2/696 19/18639 0.105263157894737 2.81896551724138 0.15704029281628 0.466824943386997 GO:0016504 peptidase activator activity 4/696 57/18639 0.0701754385964912 1.87931034482759 0.163269137396519 0.483870352647865 GO:0015103 inorganic anion transmembrane transporter activity 9/696 165/18639 0.0545454545454545 1.46073667711599 0.165106110433887 0.487836181281999 GO:0003697 single-stranded DNA binding 7/696 121/18639 0.0578512396694215 1.54926617269877 0.166980019840714 0.491014132315572 GO:0005501 retinoid binding 3/696 38/18639 0.0789473684210526 2.11422413793103 0.168189912398483 0.491014132315572 GO:0019840 isoprenoid binding 3/696 38/18639 0.0789473684210526 2.11422413793103 0.168189912398483 0.491014132315572 GO:0042887 amide transmembrane transporter activity 3/696 38/18639 0.0789473684210526 2.11422413793103 0.168189912398483 0.491014132315572 GO:0001972 retinoic acid binding 2/696 20/18639 0.1 2.67801724137931 0.170397961767519 0.491590579966471 GO:0016004 phospholipase activator activity 2/696 20/18639 0.1 2.67801724137931 0.170397961767519 0.491590579966471 GO:0016505 peptidase activator activity involved in apoptotic process 2/696 20/18639 0.1 2.67801724137931 0.170397961767519 0.491590579966471 GO:0043024 ribosomal small subunit binding 2/696 20/18639 0.1 2.67801724137931 0.170397961767519 0.491590579966471 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 7/696 122/18639 0.0573770491803279 1.53656726964387 0.171872828376452 0.494387135741677 GO:0048306 calcium-dependent protein binding 5/696 80/18639 0.0625 1.67376077586207 0.178949273967269 0.513232815073282 GO:0008238 exopeptidase activity 6/696 102/18639 0.0588235294117647 1.57530425963489 0.181836401539984 0.518530771421155 GO:0030414 peptidase inhibitor activity 9/696 169/18639 0.0532544378698225 1.42616302795348 0.181856906541366 0.518530771421155 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/696 21/18639 0.0952380952380952 2.55049261083744 0.183934570718249 0.519907543822104 GO:0019200 carbohydrate kinase activity 2/696 21/18639 0.0952380952380952 2.55049261083744 0.183934570718249 0.519907543822104 GO:0070182 DNA polymerase binding 2/696 21/18639 0.0952380952380952 2.55049261083744 0.183934570718249 0.519907543822104 GO:0019209 kinase activator activity 8/696 148/18639 0.0540540540540541 1.44757688723206 0.189511697829935 0.534128070540854 GO:0140097 catalytic activity, acting on DNA 16/696 336/18639 0.0476190476190476 1.27524630541872 0.192043534095633 0.539708552717036 GO:0008509 monoatomic anion transmembrane transporter activity 8/696 149/18639 0.0536912751677852 1.4378616061097 0.194237803826336 0.544311094963201 GO:0042169 SH2 domain binding 3/696 41/18639 0.0731707317073171 1.95952481076535 0.196503477042452 0.544424206144281 GO:0042287 MHC protein binding 3/696 41/18639 0.0731707317073171 1.95952481076535 0.196503477042452 0.544424206144281 GO:0004519 endonuclease activity 7/696 127/18639 0.0551181102362205 1.47607249524844 0.197233566455308 0.544424206144281 GO:0004407 histone deacetylase activity 2/696 22/18639 0.0909090909090909 2.43456112852665 0.19761819343683 0.544424206144281 GO:0015377 chloride:monoatomic cation symporter activity 2/696 22/18639 0.0909090909090909 2.43456112852665 0.19761819343683 0.544424206144281 GO:0033558 protein lysine deacetylase activity 2/696 22/18639 0.0909090909090909 2.43456112852665 0.19761819343683 0.544424206144281 GO:0031490 chromatin DNA binding 7/696 128/18639 0.0546875 1.46454067887931 0.202475217266494 0.55623809687256 GO:0003823 antigen binding 9/696 174/18639 0.0517241379310345 1.38518133174792 0.203808582405962 0.558332755162553 GO:0048487 beta-tubulin binding 3/696 42/18639 0.0714285714285714 1.91286945812808 0.206187446817976 0.563271851921735 GO:0000295 adenine nucleotide transmembrane transporter activity 2/696 23/18639 0.0869565217391304 2.32871064467766 0.211419032249468 0.566487160383507 GO:0003887 DNA-directed DNA polymerase activity 2/696 23/18639 0.0869565217391304 2.32871064467766 0.211419032249468 0.566487160383507 GO:0008171 O-methyltransferase activity 2/696 23/18639 0.0869565217391304 2.32871064467766 0.211419032249468 0.566487160383507 GO:0016917 GABA receptor activity 2/696 23/18639 0.0869565217391304 2.32871064467766 0.211419032249468 0.566487160383507 GO:0031681 G-protein beta-subunit binding 2/696 23/18639 0.0869565217391304 2.32871064467766 0.211419032249468 0.566487160383507 GO:0042171 lysophosphatidic acid acyltransferase activity 2/696 23/18639 0.0869565217391304 2.32871064467766 0.211419032249468 0.566487160383507 GO:0071617 lysophospholipid acyltransferase activity 2/696 23/18639 0.0869565217391304 2.32871064467766 0.211419032249468 0.566487160383507 GO:0004252 serine-type endopeptidase activity 9/696 176/18639 0.0511363636363636 1.36944063479624 0.212883298996202 0.568852094039032 GO:0046982 protein heterodimerization activity 17/696 369/18639 0.046070460704607 1.23377488085226 0.219763215942889 0.585636035945901 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 7/696 132/18639 0.053030303030303 1.42016065830721 0.22395750473399 0.59220362214122 GO:0001091 RNA polymerase II general transcription initiation factor binding 2/696 24/18639 0.0833333333333333 2.23168103448276 0.225309303969793 0.59220362214122 GO:0005315 phosphate transmembrane transporter activity 2/696 24/18639 0.0833333333333333 2.23168103448276 0.225309303969793 0.59220362214122 GO:0019957 C-C chemokine binding 2/696 24/18639 0.0833333333333333 2.23168103448276 0.225309303969793 0.59220362214122 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/696 24/18639 0.0833333333333333 2.23168103448276 0.225309303969793 0.59220362214122 GO:0001046 core promoter sequence-specific DNA binding 3/696 44/18639 0.0681818181818182 1.82592084639498 0.225860890653042 0.59220362214122 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/696 25/18639 0.08 2.14241379310345 0.239263131360043 0.623998246586992 GO:0120020 cholesterol transfer activity 2/696 25/18639 0.08 2.14241379310345 0.239263131360043 0.623998246586992 GO:0043022 ribosome binding 6/696 112/18639 0.0535714285714286 1.43465209359606 0.240951109213389 0.626729214922059 GO:0030145 manganese ion binding 4/696 68/18639 0.0588235294117647 1.57530425963489 0.248697509849254 0.645162240404697 GO:0008143 poly(A) binding 2/696 26/18639 0.0769230769230769 2.06001326259947 0.253256439870733 0.646696601027617 GO:0015216 purine nucleotide transmembrane transporter activity 2/696 26/18639 0.0769230769230769 2.06001326259947 0.253256439870733 0.646696601027617 GO:0030247 polysaccharide binding 2/696 26/18639 0.0769230769230769 2.06001326259947 0.253256439870733 0.646696601027617 GO:0050681 nuclear androgen receptor binding 2/696 26/18639 0.0769230769230769 2.06001326259947 0.253256439870733 0.646696601027617 GO:0050750 low-density lipoprotein particle receptor binding 2/696 26/18639 0.0769230769230769 2.06001326259947 0.253256439870733 0.646696601027617 GO:0070412 R-SMAD binding 2/696 26/18639 0.0769230769230769 2.06001326259947 0.253256439870733 0.646696601027617 GO:0008080 N-acetyltransferase activity 4/696 69/18639 0.0579710144927536 1.55247376311844 0.25692005950151 0.654343276542909 GO:0008094 ATP-dependent activity, acting on DNA 10/696 210/18639 0.0476190476190476 1.27524630541872 0.260377150937193 0.661425593809284 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/696 70/18639 0.0571428571428571 1.53029556650246 0.265196025335234 0.670223047460622 GO:0015294 solute:monoatomic cation symporter activity 6/696 116/18639 0.0517241379310345 1.38518133174792 0.266055524665588 0.670223047460622 GO:0004683 calcium/calmodulin-dependent protein kinase activity 2/696 27/18639 0.0740740740740741 1.98371647509579 0.267266859416813 0.670223047460622 GO:0005385 zinc ion transmembrane transporter activity 2/696 27/18639 0.0740740740740741 1.98371647509579 0.267266859416813 0.670223047460622 GO:0015252 proton channel activity 2/696 27/18639 0.0740740740740741 1.98371647509579 0.267266859416813 0.670223047460622 GO:1990782 protein tyrosine kinase binding 6/696 117/18639 0.0512820512820513 1.37334217506631 0.272434176736489 0.681433823141397 GO:0016410 N-acyltransferase activity 5/696 94/18639 0.0531914893617021 1.42447725605282 0.274393920399416 0.684584832016909 GO:0035254 glutamate receptor binding 3/696 49/18639 0.0612244897959184 1.63960239268121 0.276358589074139 0.687732061360071 GO:0140098 catalytic activity, acting on RNA 17/696 387/18639 0.0439276485788114 1.17639000267308 0.280003610312248 0.689437621749113 GO:0005242 inward rectifier potassium channel activity 2/696 28/18639 0.0714285714285714 1.91286945812808 0.281273630958994 0.689437621749113 GO:0016866 intramolecular transferase activity 2/696 28/18639 0.0714285714285714 1.91286945812808 0.281273630958994 0.689437621749113 GO:0019789 SUMO transferase activity 2/696 28/18639 0.0714285714285714 1.91286945812808 0.281273630958994 0.689437621749113 GO:0046966 nuclear thyroid hormone receptor binding 2/696 28/18639 0.0714285714285714 1.91286945812808 0.281273630958994 0.689437621749113 GO:0051019 mitogen-activated protein kinase binding 2/696 28/18639 0.0714285714285714 1.91286945812808 0.281273630958994 0.689437621749113 GO:0048020 CCR chemokine receptor binding 3/696 50/18639 0.06 1.60681034482759 0.286607530313459 0.697067880863319 GO:0016407 acetyltransferase activity 5/696 96/18639 0.0520833333333333 1.39480064655172 0.288870582367479 0.697067880863319 GO:0004521 RNA endonuclease activity 4/696 73/18639 0.0547945205479452 1.4674067076051 0.290293986248833 0.697067880863319 GO:0043236 laminin binding 2/696 29/18639 0.0689655172413793 1.84690844233056 0.295257517669154 0.697067880863319 GO:0005010 insulin-like growth factor receptor activity 3/696 51/18639 0.0588235294117647 1.57530425963489 0.296885509025046 0.697067880863319 GO:0015108 chloride transmembrane transporter activity 6/696 121/18639 0.0495867768595041 1.32794243374181 0.298291655296957 0.697067880863319 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 6/696 122/18639 0.0491803278688525 1.31705765969474 0.304830560137673 0.697067880863319 GO:0008187 poly-pyrimidine tract binding 2/696 30/18639 0.0666666666666667 1.78534482758621 0.309200720468488 0.697067880863319 GO:0015215 nucleotide transmembrane transporter activity 2/696 30/18639 0.0666666666666667 1.78534482758621 0.309200720468488 0.697067880863319 GO:0031210 phosphatidylcholine binding 2/696 30/18639 0.0666666666666667 1.78534482758621 0.309200720468488 0.697067880863319 GO:0033612 receptor serine/threonine kinase binding 2/696 30/18639 0.0666666666666667 1.78534482758621 0.309200720468488 0.697067880863319 GO:0001094 TFIID-class transcription factor complex binding 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0005131 growth hormone receptor binding 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0005337 nucleoside transmembrane transporter activity 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0005345 purine nucleobase transmembrane transporter activity 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0008140 cAMP response element binding protein binding 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0015203 polyamine transmembrane transporter activity 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0016868 intramolecular phosphotransferase activity 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0019911 structural constituent of myelin sheath 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0030957 Tat protein binding 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0031434 mitogen-activated protein kinase kinase binding 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0031996 thioesterase binding 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0042166 acetylcholine binding 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0043208 glycosphingolipid binding 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0045322 unmethylated CpG binding 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0050308 sugar-phosphatase activity 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0050815 phosphoserine residue binding 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0051880 G-quadruplex DNA binding 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0070097 delta-catenin binding 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0070513 death domain binding 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0140940 histone H2A methyltransferase activity 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0140999 histone H3K4 trimethyltransferase activity 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0141109 transporter activator activity 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:1990259 histone H2AQ104 methyltransferase activity 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:1990757 ubiquitin ligase activator activity 1/696 10/18639 0.1 2.67801724137931 0.316586108075842 0.697067880863319 GO:0004864 protein phosphatase inhibitor activity 3/696 53/18639 0.0566037735849057 1.51585881587508 0.317495445939986 0.697067880863319 GO:0034212 protein N-acetyltransferase activity 3/696 53/18639 0.0566037735849057 1.51585881587508 0.317495445939986 0.697067880863319 GO:0038064 collagen receptor activity 3/696 53/18639 0.0566037735849057 1.51585881587508 0.317495445939986 0.697067880863319 GO:1901505 carbohydrate derivative transmembrane transporter activity 3/696 53/18639 0.0566037735849057 1.51585881587508 0.317495445939986 0.697067880863319 GO:0033218 amide binding 11/696 247/18639 0.0445344129554656 1.19263925729443 0.318291119516349 0.697067880863319 GO:0042393 histone binding 11/696 247/18639 0.0445344129554656 1.19263925729443 0.318291119516349 0.697067880863319 GO:0005452 solute:inorganic anion antiporter activity 2/696 31/18639 0.0645161290322581 1.72775305895439 0.323086797736444 0.697067880863319 GO:0016411 acylglycerol O-acyltransferase activity 2/696 31/18639 0.0645161290322581 1.72775305895439 0.323086797736444 0.697067880863319 GO:0017147 Wnt-protein binding 2/696 31/18639 0.0645161290322581 1.72775305895439 0.323086797736444 0.697067880863319 GO:0051287 NAD binding 3/696 54/18639 0.0555555555555556 1.48778735632184 0.327811538847869 0.697067880863319 GO:0140463 chromatin-protein adaptor activity 3/696 54/18639 0.0555555555555556 1.48778735632184 0.327811538847869 0.697067880863319 GO:0015106 bicarbonate transmembrane transporter activity 2/696 32/18639 0.0625 1.67376077586207 0.336900588997414 0.697067880863319 GO:0042910 xenobiotic transmembrane transporter activity 2/696 32/18639 0.0625 1.67376077586207 0.336900588997414 0.697067880863319 GO:0051059 NF-kappaB binding 2/696 32/18639 0.0625 1.67376077586207 0.336900588997414 0.697067880863319 GO:0070717 poly-purine tract binding 2/696 32/18639 0.0625 1.67376077586207 0.336900588997414 0.697067880863319 GO:0120015 sterol transfer activity 2/696 32/18639 0.0625 1.67376077586207 0.336900588997414 0.697067880863319 GO:0033293 monocarboxylic acid binding 4/696 79/18639 0.0506329113924051 1.35595809690092 0.341269406337235 0.697067880863319 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0005225 volume-sensitive anion channel activity 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0008172 S-methyltransferase activity 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0008199 ferric iron binding 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0008526 phosphatidylinositol transfer activity 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0015205 nucleobase transmembrane transporter activity 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0015217 ADP transmembrane transporter activity 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0019203 carbohydrate phosphatase activity 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0031731 CCR6 chemokine receptor binding 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0032050 clathrin heavy chain binding 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0032794 GTPase activating protein binding 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0045294 alpha-catenin binding 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0048185 activin binding 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0048407 platelet-derived growth factor binding 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0070697 activin receptor binding 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0070990 snRNP binding 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0140537 transcription regulator activator activity 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/696 11/18639 0.0909090909090909 2.43456112852665 0.34211920533169 0.697067880863319 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 6/696 128/18639 0.046875 1.25532058189655 0.344520093684765 0.700500315225987 GO:0019212 phosphatase inhibitor activity 3/696 56/18639 0.0535714285714286 1.43465209359606 0.348428428684747 0.704055791846451 GO:0030170 pyridoxal phosphate binding 3/696 56/18639 0.0535714285714286 1.43465209359606 0.348428428684747 0.704055791846451 GO:0170055 lipid transmembrane transporter activity 3/696 56/18639 0.0535714285714286 1.43465209359606 0.348428428684747 0.704055791846451 GO:0019956 chemokine binding 2/696 33/18639 0.0606060606060606 1.6230407523511 0.350628142400742 0.707039841789538 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 6/696 130/18639 0.0461538461538462 1.23600795755968 0.35787185866562 0.707361507821961 GO:0015932 nucleobase-containing compound transmembrane transporter activity 3/696 57/18639 0.0526315789473684 1.40948275862069 0.358715055978537 0.707361507821961 GO:0070279 vitamin B6 binding 3/696 57/18639 0.0526315789473684 1.40948275862069 0.358715055978537 0.707361507821961 GO:0015035 protein-disulfide reductase activity 2/696 34/18639 0.0588235294117647 1.57530425963489 0.364256645817808 0.707361507821961 GO:0030332 cyclin binding 2/696 34/18639 0.0588235294117647 1.57530425963489 0.364256645817808 0.707361507821961 GO:0004000 adenosine deaminase activity 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0004300 enoyl-CoA hydratase activity 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0005095 GTPase inhibitor activity 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0008179 adenylate cyclase binding 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0008504 monoamine transmembrane transporter activity 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0015132 prostaglandin transmembrane transporter activity 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0015269 calcium-activated potassium channel activity 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0016208 AMP binding 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0035197 siRNA binding 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0035497 cAMP response element binding 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0036009 protein-glutamine N-methyltransferase activity 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0043047 single-stranded telomeric DNA binding 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0070679 inositol 1,4,5 trisphosphate binding 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0140900 chloride:bicarbonate antiporter activity 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/696 12/18639 0.0833333333333333 2.23168103448276 0.366699677367826 0.707361507821961 GO:0005496 steroid binding 5/696 108/18639 0.0462962962962963 1.23982279693487 0.377674229112692 0.716367827169904 GO:0005154 epidermal growth factor receptor binding 2/696 35/18639 0.0571428571428571 1.53029556650246 0.377774361387758 0.716367827169904 GO:0034061 DNA polymerase activity 2/696 35/18639 0.0571428571428571 1.53029556650246 0.377774361387758 0.716367827169904 GO:0043015 gamma-tubulin binding 2/696 35/18639 0.0571428571428571 1.53029556650246 0.377774361387758 0.716367827169904 GO:0015459 potassium channel regulator activity 3/696 59/18639 0.0508474576271186 1.36170368205728 0.379211360828048 0.716367827169904 GO:0031593 polyubiquitin modification-dependent protein binding 3/696 59/18639 0.0508474576271186 1.36170368205728 0.379211360828048 0.716367827169904 GO:0036002 pre-mRNA binding 3/696 59/18639 0.0508474576271186 1.36170368205728 0.379211360828048 0.716367827169904 GO:0045309 protein phosphorylated amino acid binding 3/696 59/18639 0.0508474576271186 1.36170368205728 0.379211360828048 0.716367827169904 GO:0070888 E-box binding 3/696 59/18639 0.0508474576271186 1.36170368205728 0.379211360828048 0.716367827169904 GO:0004518 nuclease activity 9/696 209/18639 0.0430622009569378 1.1532131661442 0.379425904370154 0.716367827169904 GO:0051015 actin filament binding 9/696 209/18639 0.0430622009569378 1.1532131661442 0.379425904370154 0.716367827169904 GO:0004620 phospholipase activity 5/696 109/18639 0.0458715596330275 1.22844827586207 0.385128947022903 0.718973692053148 GO:0015291 secondary active transmembrane transporter activity 12/696 287/18639 0.0418118466898955 1.11972846329449 0.386010647550562 0.718973692053148 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/696 60/18639 0.05 1.33900862068966 0.389408548258129 0.718973692053148 GO:0002161 aminoacyl-tRNA editing activity 1/696 13/18639 0.0769230769230769 2.06001326259947 0.390363016850942 0.718973692053148 GO:0005542 folic acid binding 1/696 13/18639 0.0769230769230769 2.06001326259947 0.390363016850942 0.718973692053148 GO:0019855 calcium channel inhibitor activity 1/696 13/18639 0.0769230769230769 2.06001326259947 0.390363016850942 0.718973692053148 GO:0031994 insulin-like growth factor I binding 1/696 13/18639 0.0769230769230769 2.06001326259947 0.390363016850942 0.718973692053148 GO:0046974 histone H3K9 methyltransferase activity 1/696 13/18639 0.0769230769230769 2.06001326259947 0.390363016850942 0.718973692053148 GO:0070700 BMP receptor binding 1/696 13/18639 0.0769230769230769 2.06001326259947 0.390363016850942 0.718973692053148 GO:0071714 icosanoid transmembrane transporter activity 1/696 13/18639 0.0769230769230769 2.06001326259947 0.390363016850942 0.718973692053148 GO:0071837 HMG box domain binding 1/696 13/18639 0.0769230769230769 2.06001326259947 0.390363016850942 0.718973692053148 GO:0089720 caspase binding 1/696 13/18639 0.0769230769230769 2.06001326259947 0.390363016850942 0.718973692053148 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/696 13/18639 0.0769230769230769 2.06001326259947 0.390363016850942 0.718973692053148 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 3/696 61/18639 0.0491803278688525 1.31705765969474 0.399563890183352 0.733158507691029 GO:0019905 syntaxin binding 3/696 61/18639 0.0491803278688525 1.31705765969474 0.399563890183352 0.733158507691029 GO:0019213 deacetylase activity 2/696 37/18639 0.0540540540540541 1.44757688723206 0.404435479016757 0.73598222440011 GO:0022829 wide pore channel activity 2/696 37/18639 0.0540540540540541 1.44757688723206 0.404435479016757 0.73598222440011 GO:0005200 structural constituent of cytoskeleton 5/696 112/18639 0.0446428571428571 1.19554341133005 0.407455230329047 0.73598222440011 GO:0005545 1-phosphatidylinositol binding 1/696 14/18639 0.0714285714285714 1.91286945812808 0.413143395905583 0.73598222440011 GO:0008191 metalloendopeptidase inhibitor activity 1/696 14/18639 0.0714285714285714 1.91286945812808 0.413143395905583 0.73598222440011 GO:0008195 phosphatidate phosphatase activity 1/696 14/18639 0.0714285714285714 1.91286945812808 0.413143395905583 0.73598222440011 GO:0008559 ABC-type xenobiotic transporter activity 1/696 14/18639 0.0714285714285714 1.91286945812808 0.413143395905583 0.73598222440011 GO:0019763 immunoglobulin receptor activity 1/696 14/18639 0.0714285714285714 1.91286945812808 0.413143395905583 0.73598222440011 GO:0019992 diacylglycerol binding 1/696 14/18639 0.0714285714285714 1.91286945812808 0.413143395905583 0.73598222440011 GO:0032454 histone H3K9 demethylase activity 1/696 14/18639 0.0714285714285714 1.91286945812808 0.413143395905583 0.73598222440011 GO:0042813 Wnt receptor activity 1/696 14/18639 0.0714285714285714 1.91286945812808 0.413143395905583 0.73598222440011 GO:0044548 S100 protein binding 1/696 14/18639 0.0714285714285714 1.91286945812808 0.413143395905583 0.73598222440011 GO:0061665 SUMO ligase activity 1/696 14/18639 0.0714285714285714 1.91286945812808 0.413143395905583 0.73598222440011 GO:0070742 C2H2 zinc finger domain binding 1/696 14/18639 0.0714285714285714 1.91286945812808 0.413143395905583 0.73598222440011 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/696 14/18639 0.0714285714285714 1.91286945812808 0.413143395905583 0.73598222440011 GO:1901474 azole transmembrane transporter activity 1/696 14/18639 0.0714285714285714 1.91286945812808 0.413143395905583 0.73598222440011 GO:0043531 ADP binding 2/696 38/18639 0.0526315789473684 1.40948275862069 0.417560232717773 0.738296861850972 GO:0004197 cysteine-type endopeptidase activity 4/696 88/18639 0.0454545454545455 1.21728056426332 0.417892942207666 0.738296861850972 GO:0070851 growth factor receptor binding 6/696 139/18639 0.0431654676258993 1.15597866534359 0.4181307298758 0.738296861850972 GO:0140767 enzyme-substrate adaptor activity 6/696 139/18639 0.0431654676258993 1.15597866534359 0.4181307298758 0.738296861850972 GO:0005507 copper ion binding 3/696 63/18639 0.0476190476190476 1.27524630541872 0.419727050295645 0.738296861850972 GO:0022824 transmitter-gated monoatomic ion channel activity 3/696 63/18639 0.0476190476190476 1.27524630541872 0.419727050295645 0.738296861850972 GO:0022835 transmitter-gated channel activity 3/696 63/18639 0.0476190476190476 1.27524630541872 0.419727050295645 0.738296861850972 GO:0008514 organic anion transmembrane transporter activity 11/696 269/18639 0.0408921933085502 1.09509998718113 0.42265541388081 0.742113096544762 GO:0004536 DNA nuclease activity 3/696 64/18639 0.046875 1.25532058189655 0.429724535442585 0.745187554192879 GO:0000217 DNA secondary structure binding 2/696 39/18639 0.0512820512820513 1.37334217506631 0.430536792611988 0.745187554192879 GO:0001664 G protein-coupled receptor binding 12/696 297/18639 0.0404040404040404 1.08202716823406 0.431753342580127 0.745187554192879 GO:0000774 adenyl-nucleotide exchange factor activity 1/696 15/18639 0.0666666666666667 1.78534482758621 0.435073715178051 0.745187554192879 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/696 15/18639 0.0666666666666667 1.78534482758621 0.435073715178051 0.745187554192879 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/696 15/18639 0.0666666666666667 1.78534482758621 0.435073715178051 0.745187554192879 GO:0015250 water channel activity 1/696 15/18639 0.0666666666666667 1.78534482758621 0.435073715178051 0.745187554192879 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/696 15/18639 0.0666666666666667 1.78534482758621 0.435073715178051 0.745187554192879 GO:0015929 hexosaminidase activity 1/696 15/18639 0.0666666666666667 1.78534482758621 0.435073715178051 0.745187554192879 GO:0031005 filamin binding 1/696 15/18639 0.0666666666666667 1.78534482758621 0.435073715178051 0.745187554192879 GO:0034483 heparan sulfate sulfotransferase activity 1/696 15/18639 0.0666666666666667 1.78534482758621 0.435073715178051 0.745187554192879 GO:0050780 dopamine receptor binding 1/696 15/18639 0.0666666666666667 1.78534482758621 0.435073715178051 0.745187554192879 GO:0120283 protein serine/threonine kinase binding 1/696 15/18639 0.0666666666666667 1.78534482758621 0.435073715178051 0.745187554192879 GO:0140161 monocarboxylate:sodium symporter activity 1/696 15/18639 0.0666666666666667 1.78534482758621 0.435073715178051 0.745187554192879 GO:0019843 rRNA binding 3/696 65/18639 0.0461538461538462 1.23600795755968 0.439659499955627 0.750413596782903 GO:0120013 lipid transfer activity 3/696 65/18639 0.0461538461538462 1.23600795755968 0.439659499955627 0.750413596782903 GO:0015036 disulfide oxidoreductase activity 2/696 40/18639 0.05 1.33900862068966 0.443357920197114 0.754093992961352 GO:0050997 quaternary ammonium group binding 2/696 40/18639 0.05 1.33900862068966 0.443357920197114 0.754093992961352 GO:0008235 metalloexopeptidase activity 3/696 66/18639 0.0454545454545455 1.21728056426332 0.449527416987416 0.761347383542908 GO:0019955 cytokine binding 6/696 144/18639 0.0416666666666667 1.11584051724138 0.451375535907796 0.761347383542908 GO:0001530 lipopolysaccharide binding 2/696 41/18639 0.0487804878048781 1.30634987384357 0.456017122410174 0.761347383542908 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/696 16/18639 0.0625 1.67376077586207 0.456185651079902 0.761347383542908 GO:0015378 sodium:chloride symporter activity 1/696 16/18639 0.0625 1.67376077586207 0.456185651079902 0.761347383542908 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/696 16/18639 0.0625 1.67376077586207 0.456185651079902 0.761347383542908 GO:0016722 oxidoreductase activity, acting on metal ions 1/696 16/18639 0.0625 1.67376077586207 0.456185651079902 0.761347383542908 GO:0019841 retinol binding 1/696 16/18639 0.0625 1.67376077586207 0.456185651079902 0.761347383542908 GO:0022841 potassium ion leak channel activity 1/696 16/18639 0.0625 1.67376077586207 0.456185651079902 0.761347383542908 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/696 16/18639 0.0625 1.67376077586207 0.456185651079902 0.761347383542908 GO:0055102 lipase inhibitor activity 1/696 16/18639 0.0625 1.67376077586207 0.456185651079902 0.761347383542908 GO:0016500 protein-hormone receptor activity 3/696 67/18639 0.0447761194029851 1.19911219763253 0.459324006400536 0.763225434311412 GO:0042054 histone methyltransferase activity 3/696 67/18639 0.0447761194029851 1.19911219763253 0.459324006400536 0.763225434311412 GO:0051219 phosphoprotein binding 4/696 93/18639 0.043010752688172 1.15183537263626 0.459652127616995 0.763225434311412 GO:0015293 symporter activity 6/696 146/18639 0.0410958904109589 1.10055503070383 0.464561054523739 0.770069002244436 GO:0032182 ubiquitin-like protein binding 5/696 120/18639 0.0416666666666667 1.11584051724138 0.466285615678765 0.770086414880014 GO:0004402 histone acetyltransferase activity 2/696 42/18639 0.0476190476190476 1.27524630541872 0.468508606189783 0.770086414880014 GO:0004520 DNA endonuclease activity 2/696 42/18639 0.0476190476190476 1.27524630541872 0.468508606189783 0.770086414880014 GO:0019894 kinesin binding 2/696 42/18639 0.0476190476190476 1.27524630541872 0.468508606189783 0.770086414880014 GO:0051879 Hsp90 protein binding 2/696 42/18639 0.0476190476190476 1.27524630541872 0.468508606189783 0.770086414880014 GO:0004540 RNA nuclease activity 5/696 121/18639 0.0413223140495868 1.10661869478484 0.47352673466074 0.771567032864848 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/696 17/18639 0.0588235294117647 1.57530425963489 0.476509701278495 0.771567032864848 GO:0004659 prenyltransferase activity 1/696 17/18639 0.0588235294117647 1.57530425963489 0.476509701278495 0.771567032864848 GO:0008484 sulfuric ester hydrolase activity 1/696 17/18639 0.0588235294117647 1.57530425963489 0.476509701278495 0.771567032864848 GO:0008569 minus-end-directed microtubule motor activity 1/696 17/18639 0.0588235294117647 1.57530425963489 0.476509701278495 0.771567032864848 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/696 17/18639 0.0588235294117647 1.57530425963489 0.476509701278495 0.771567032864848 GO:0015278 intracellularly gated calcium channel activity 1/696 17/18639 0.0588235294117647 1.57530425963489 0.476509701278495 0.771567032864848 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/696 17/18639 0.0588235294117647 1.57530425963489 0.476509701278495 0.771567032864848 GO:0070492 oligosaccharide binding 1/696 17/18639 0.0588235294117647 1.57530425963489 0.476509701278495 0.771567032864848 GO:0002039 p53 binding 3/696 69/18639 0.0434782608695652 1.16435532233883 0.478687282491778 0.773811838474312 GO:0008200 ion channel inhibitor activity 2/696 43/18639 0.0465116279069767 1.24558941459503 0.480827235384457 0.775988508590757 GO:0004896 cytokine receptor activity 4/696 96/18639 0.0416666666666667 1.11584051724138 0.484212859780534 0.780165036022014 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 9/696 229/18639 0.0393013100436681 1.05249585905737 0.485789667327764 0.781418247773937 GO:0005085 guanyl-nucleotide exchange factor activity 9/696 230/18639 0.0391304347826087 1.04791979010495 0.491029631013854 0.782295473248553 GO:0016248 channel inhibitor activity 2/696 44/18639 0.0454545454545455 1.21728056426332 0.492968489895476 0.782295473248553 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/696 44/18639 0.0454545454545455 1.21728056426332 0.492968489895476 0.782295473248553 GO:0000900 mRNA regulatory element binding translation repressor activity 1/696 18/18639 0.0555555555555556 1.48778735632184 0.496075228499533 0.782295473248553 GO:0005372 water transmembrane transporter activity 1/696 18/18639 0.0555555555555556 1.48778735632184 0.496075228499533 0.782295473248553 GO:0008409 5'-3' exonuclease activity 1/696 18/18639 0.0555555555555556 1.48778735632184 0.496075228499533 0.782295473248553 GO:0008525 phosphatidylcholine transporter activity 1/696 18/18639 0.0555555555555556 1.48778735632184 0.496075228499533 0.782295473248553 GO:0015373 monoatomic anion:sodium symporter activity 1/696 18/18639 0.0555555555555556 1.48778735632184 0.496075228499533 0.782295473248553 GO:0031690 adrenergic receptor binding 1/696 18/18639 0.0555555555555556 1.48778735632184 0.496075228499533 0.782295473248553 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/696 18/18639 0.0555555555555556 1.48778735632184 0.496075228499533 0.782295473248553 GO:0098641 cadherin binding involved in cell-cell adhesion 1/696 18/18639 0.0555555555555556 1.48778735632184 0.496075228499533 0.782295473248553 GO:1901611 phosphatidylglycerol binding 1/696 18/18639 0.0555555555555556 1.48778735632184 0.496075228499533 0.782295473248553 GO:0140299 molecular sensor activity 3/696 71/18639 0.0422535211267606 1.1315565808645 0.497719809906907 0.782295473248553 GO:0005319 lipid transporter activity 7/696 178/18639 0.0393258426966292 1.05315284773344 0.498815589651299 0.782295473248553 GO:0008009 chemokine activity 2/696 45/18639 0.0444444444444444 1.19022988505747 0.50492842694792 0.782295473248553 GO:0051539 4 iron, 4 sulfur cluster binding 2/696 45/18639 0.0444444444444444 1.19022988505747 0.50492842694792 0.782295473248553 GO:0141110 transporter inhibitor activity 2/696 45/18639 0.0444444444444444 1.19022988505747 0.50492842694792 0.782295473248553 GO:0042379 chemokine receptor binding 3/696 72/18639 0.0416666666666667 1.11584051724138 0.507103803113341 0.782295473248553 GO:0003756 protein disulfide isomerase activity 1/696 19/18639 0.0526315789473684 1.40948275862069 0.514910502704158 0.782295473248553 GO:0005520 insulin-like growth factor binding 1/696 19/18639 0.0526315789473684 1.40948275862069 0.514910502704158 0.782295473248553 GO:0015245 fatty acid transmembrane transporter activity 1/696 19/18639 0.0526315789473684 1.40948275862069 0.514910502704158 0.782295473248553 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/696 19/18639 0.0526315789473684 1.40948275862069 0.514910502704158 0.782295473248553 GO:0016918 retinal binding 1/696 19/18639 0.0526315789473684 1.40948275862069 0.514910502704158 0.782295473248553 GO:0022840 leak channel activity 1/696 19/18639 0.0526315789473684 1.40948275862069 0.514910502704158 0.782295473248553 GO:0022842 narrow pore channel activity 1/696 19/18639 0.0526315789473684 1.40948275862069 0.514910502704158 0.782295473248553 GO:0030506 ankyrin binding 1/696 19/18639 0.0526315789473684 1.40948275862069 0.514910502704158 0.782295473248553 GO:0042800 histone H3K4 methyltransferase activity 1/696 19/18639 0.0526315789473684 1.40948275862069 0.514910502704158 0.782295473248553 GO:0042834 peptidoglycan binding 1/696 19/18639 0.0526315789473684 1.40948275862069 0.514910502704158 0.782295473248553 GO:0043395 heparan sulfate proteoglycan binding 1/696 19/18639 0.0526315789473684 1.40948275862069 0.514910502704158 0.782295473248553 GO:0140036 ubiquitin-modified protein reader activity 1/696 19/18639 0.0526315789473684 1.40948275862069 0.514910502704158 0.782295473248553 GO:1990380 K48-linked deubiquitinase activity 1/696 19/18639 0.0526315789473684 1.40948275862069 0.514910502704158 0.782295473248553 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/696 73/18639 0.0410958904109589 1.10055503070383 0.516395652407535 0.782295473248553 GO:0043539 protein serine/threonine kinase activator activity 3/696 73/18639 0.0410958904109589 1.10055503070383 0.516395652407535 0.782295473248553 GO:0030276 clathrin binding 2/696 46/18639 0.0434782608695652 1.16435532233883 0.516703644388227 0.782295473248553 GO:0003678 DNA helicase activity 3/696 74/18639 0.0405405405405405 1.08568266542404 0.525592643756072 0.782295473248553 GO:0031491 nucleosome binding 3/696 74/18639 0.0405405405405405 1.08568266542404 0.525592643756072 0.782295473248553 GO:0001784 phosphotyrosine residue binding 2/696 47/18639 0.0425531914893617 1.13958180484226 0.528291245911316 0.782295473248553 GO:0043495 protein-membrane adaptor activity 2/696 47/18639 0.0425531914893617 1.13958180484226 0.528291245911316 0.782295473248553 GO:0061733 protein-lysine-acetyltransferase activity 2/696 47/18639 0.0425531914893617 1.13958180484226 0.528291245911316 0.782295473248553 GO:0099095 ligand-gated monoatomic anion channel activity 2/696 47/18639 0.0425531914893617 1.13958180484226 0.528291245911316 0.782295473248553 GO:0140938 histone H3 methyltransferase activity 2/696 47/18639 0.0425531914893617 1.13958180484226 0.528291245911316 0.782295473248553 GO:0000339 RNA cap binding 1/696 20/18639 0.05 1.33900862068966 0.533042741700823 0.782295473248553 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/696 20/18639 0.05 1.33900862068966 0.533042741700823 0.782295473248553 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/696 20/18639 0.05 1.33900862068966 0.533042741700823 0.782295473248553 GO:0015464 acetylcholine receptor activity 1/696 20/18639 0.05 1.33900862068966 0.533042741700823 0.782295473248553 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/696 20/18639 0.05 1.33900862068966 0.533042741700823 0.782295473248553 GO:0030742 GTP-dependent protein binding 1/696 20/18639 0.05 1.33900862068966 0.533042741700823 0.782295473248553 GO:0052745 inositol phosphate phosphatase activity 1/696 20/18639 0.05 1.33900862068966 0.533042741700823 0.782295473248553 GO:0016298 lipase activity 5/696 130/18639 0.0384615384615385 1.03000663129973 0.537048679864136 0.782295473248553 GO:0005253 monoatomic anion channel activity 4/696 103/18639 0.0388349514563107 1.04000669568129 0.539634700812634 0.782295473248553 GO:0015276 ligand-gated monoatomic ion channel activity 7/696 186/18639 0.0376344086021505 1.00785595105673 0.545531689382779 0.782295473248553 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/696 21/18639 0.0476190476190476 1.27524630541872 0.550498150249952 0.782295473248553 GO:0005123 death receptor binding 1/696 21/18639 0.0476190476190476 1.27524630541872 0.550498150249952 0.782295473248553 GO:0005248 voltage-gated sodium channel activity 1/696 21/18639 0.0476190476190476 1.27524630541872 0.550498150249952 0.782295473248553 GO:0008373 sialyltransferase activity 1/696 21/18639 0.0476190476190476 1.27524630541872 0.550498150249952 0.782295473248553 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/696 21/18639 0.0476190476190476 1.27524630541872 0.550498150249952 0.782295473248553 GO:0015125 bile acid transmembrane transporter activity 1/696 21/18639 0.0476190476190476 1.27524630541872 0.550498150249952 0.782295473248553 GO:0035613 RNA stem-loop binding 1/696 21/18639 0.0476190476190476 1.27524630541872 0.550498150249952 0.782295473248553 GO:0051010 microtubule plus-end binding 1/696 21/18639 0.0476190476190476 1.27524630541872 0.550498150249952 0.782295473248553 GO:0061891 calcium ion sensor activity 1/696 21/18639 0.0476190476190476 1.27524630541872 0.550498150249952 0.782295473248553 GO:0072542 protein phosphatase activator activity 1/696 21/18639 0.0476190476190476 1.27524630541872 0.550498150249952 0.782295473248553 GO:0005004 GPI-linked ephrin receptor activity 2/696 49/18639 0.0408163265306122 1.09306826178747 0.550894349360841 0.782295473248553 GO:0005008 hepatocyte growth factor receptor activity 2/696 49/18639 0.0408163265306122 1.09306826178747 0.550894349360841 0.782295473248553 GO:0005009 insulin receptor activity 2/696 49/18639 0.0408163265306122 1.09306826178747 0.550894349360841 0.782295473248553 GO:0005011 macrophage colony-stimulating factor receptor activity 2/696 49/18639 0.0408163265306122 1.09306826178747 0.550894349360841 0.782295473248553 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/696 49/18639 0.0408163265306122 1.09306826178747 0.550894349360841 0.782295473248553 GO:0005020 stem cell factor receptor activity 2/696 49/18639 0.0408163265306122 1.09306826178747 0.550894349360841 0.782295473248553 GO:0008288 boss receptor activity 2/696 49/18639 0.0408163265306122 1.09306826178747 0.550894349360841 0.782295473248553 GO:0016763 pentosyltransferase activity 2/696 49/18639 0.0408163265306122 1.09306826178747 0.550894349360841 0.782295473248553 GO:0036332 placental growth factor receptor activity 2/696 49/18639 0.0408163265306122 1.09306826178747 0.550894349360841 0.782295473248553 GO:0038062 protein tyrosine kinase collagen receptor activity 2/696 49/18639 0.0408163265306122 1.09306826178747 0.550894349360841 0.782295473248553 GO:0060175 brain-derived neurotrophic factor receptor activity 2/696 49/18639 0.0408163265306122 1.09306826178747 0.550894349360841 0.782295473248553 GO:0005525 GTP binding 14/696 378/18639 0.037037037037037 0.991858237547893 0.551101713538873 0.782295473248553 GO:0022834 ligand-gated channel activity 7/696 188/18639 0.0372340425531915 0.997134079236977 0.556927939749275 0.782295473248553 GO:0019199 transmembrane receptor protein kinase activity 3/696 78/18639 0.0384615384615385 1.03000663129973 0.561384602186253 0.782295473248553 GO:0005006 epidermal growth factor receptor activity 2/696 50/18639 0.04 1.07120689655172 0.561906300154481 0.782295473248553 GO:0005007 fibroblast growth factor receptor activity 2/696 50/18639 0.04 1.07120689655172 0.561906300154481 0.782295473248553 GO:0005017 platelet-derived growth factor receptor activity 2/696 50/18639 0.04 1.07120689655172 0.561906300154481 0.782295473248553 GO:0005019 platelet-derived growth factor beta-receptor activity 2/696 50/18639 0.04 1.07120689655172 0.561906300154481 0.782295473248553 GO:0015605 organophosphate ester transmembrane transporter activity 2/696 50/18639 0.04 1.07120689655172 0.561906300154481 0.782295473248553 GO:0005243 gap junction channel activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0008649 rRNA methyltransferase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0032931 histone H3K56 acetyltransferase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0034062 5'-3' RNA polymerase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0043992 histone H3K9 acetyltransferase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0043993 histone H3K18 acetyltransferase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0043994 histone H3K23 acetyltransferase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0043999 histone H2AK5 acetyltransferase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0044012 histone H2AK9 acetyltransferase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0044014 histone H2BK5 acetyltransferase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0044015 histone H2BK12 acetyltransferase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0044016 histone H3K4 acetyltransferase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0044017 histone H3K27 acetyltransferase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0044018 histone H3K36 acetyltransferase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0046972 histone H4K16 acetyltransferase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0061133 endopeptidase activator activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0070034 telomerase RNA binding 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0097747 RNA polymerase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0140035 ubiquitin-like protein reader activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0140784 metal ion sensor activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0140908 histone H3K122 acetyltransferase activity 1/696 22/18639 0.0454545454545455 1.21728056426332 0.567301957717243 0.782295473248553 GO:0015370 solute:sodium symporter activity 3/696 79/18639 0.0379746835443038 1.01696857267569 0.570073359917135 0.782295473248553 GO:0016835 carbon-oxygen lyase activity 3/696 79/18639 0.0379746835443038 1.01696857267569 0.570073359917135 0.782295473248553 GO:0046332 SMAD binding 3/696 79/18639 0.0379746835443038 1.01696857267569 0.570073359917135 0.782295473248553 GO:0005021 vascular endothelial growth factor receptor activity 2/696 51/18639 0.0392156862745098 1.05020283975659 0.572723475302622 0.782295473248553 GO:0005030 neurotrophin receptor activity 2/696 51/18639 0.0392156862745098 1.05020283975659 0.572723475302622 0.782295473248553 GO:0005272 sodium channel activity 2/696 51/18639 0.0392156862745098 1.05020283975659 0.572723475302622 0.782295473248553 GO:0016597 amino acid binding 2/696 51/18639 0.0392156862745098 1.05020283975659 0.572723475302622 0.782295473248553 GO:0099094 ligand-gated monoatomic cation channel activity 5/696 136/18639 0.0367647058823529 0.984565162271805 0.577372018089793 0.783848802656824 GO:0005080 protein kinase C binding 2/696 52/18639 0.0384615384615385 1.03000663129973 0.583345047432105 0.783848802656824 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/696 23/18639 0.0434782608695652 1.16435532233883 0.583478454329415 0.783848802656824 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/696 23/18639 0.0434782608695652 1.16435532233883 0.583478454329415 0.783848802656824 GO:0004602 glutathione peroxidase activity 1/696 23/18639 0.0434782608695652 1.16435532233883 0.583478454329415 0.783848802656824 GO:0005212 structural constituent of eye lens 1/696 23/18639 0.0434782608695652 1.16435532233883 0.583478454329415 0.783848802656824 GO:0005283 amino acid:sodium symporter activity 1/696 23/18639 0.0434782608695652 1.16435532233883 0.583478454329415 0.783848802656824 GO:0016493 C-C chemokine receptor activity 1/696 23/18639 0.0434782608695652 1.16435532233883 0.583478454329415 0.783848802656824 GO:0043274 phospholipase binding 1/696 23/18639 0.0434782608695652 1.16435532233883 0.583478454329415 0.783848802656824 GO:0044013 histone H2B acetyltransferase activity 1/696 23/18639 0.0434782608695652 1.16435532233883 0.583478454329415 0.783848802656824 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/696 23/18639 0.0434782608695652 1.16435532233883 0.583478454329415 0.783848802656824 GO:0140102 catalytic activity, acting on a rRNA 1/696 23/18639 0.0434782608695652 1.16435532233883 0.583478454329415 0.783848802656824 GO:0005003 ephrin receptor activity 2/696 53/18639 0.0377358490566038 1.01057254391672 0.593770522000423 0.78958477562039 GO:0005005 transmembrane-ephrin receptor activity 2/696 53/18639 0.0377358490566038 1.01057254391672 0.593770522000423 0.78958477562039 GO:0005246 calcium channel regulator activity 2/696 53/18639 0.0377358490566038 1.01057254391672 0.593770522000423 0.78958477562039 GO:0008146 sulfotransferase activity 2/696 53/18639 0.0377358490566038 1.01057254391672 0.593770522000423 0.78958477562039 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/696 24/18639 0.0416666666666667 1.11584051724138 0.599051026084181 0.78958477562039 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/696 24/18639 0.0416666666666667 1.11584051724138 0.599051026084181 0.78958477562039 GO:0015295 solute:proton symporter activity 1/696 24/18639 0.0416666666666667 1.11584051724138 0.599051026084181 0.78958477562039 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/696 24/18639 0.0416666666666667 1.11584051724138 0.599051026084181 0.78958477562039 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/696 24/18639 0.0416666666666667 1.11584051724138 0.599051026084181 0.78958477562039 GO:0043998 histone H2A acetyltransferase activity 1/696 24/18639 0.0416666666666667 1.11584051724138 0.599051026084181 0.78958477562039 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/696 24/18639 0.0416666666666667 1.11584051724138 0.599051026084181 0.78958477562039 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/696 24/18639 0.0416666666666667 1.11584051724138 0.599051026084181 0.78958477562039 GO:0050431 transforming growth factor beta binding 1/696 24/18639 0.0416666666666667 1.11584051724138 0.599051026084181 0.78958477562039 GO:0070300 phosphatidic acid binding 1/696 24/18639 0.0416666666666667 1.11584051724138 0.599051026084181 0.78958477562039 GO:0005254 chloride channel activity 3/696 83/18639 0.036144578313253 0.967958039052763 0.603743014406553 0.792901637529683 GO:0030165 PDZ domain binding 3/696 83/18639 0.036144578313253 0.967958039052763 0.603743014406553 0.792901637529683 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/696 54/18639 0.037037037037037 0.991858237547893 0.603999713660137 0.792901637529683 GO:0004527 exonuclease activity 3/696 84/18639 0.0357142857142857 0.956434729064039 0.611882998478759 0.794356164312616 GO:0008374 O-acyltransferase activity 2/696 55/18639 0.0363636363636364 0.973824451410658 0.614032723920118 0.794356164312616 GO:0003707 nuclear steroid receptor activity 1/696 25/18639 0.04 1.07120689655172 0.614042188364354 0.794356164312616 GO:0015645 fatty acid ligase activity 1/696 25/18639 0.04 1.07120689655172 0.614042188364354 0.794356164312616 GO:0015662 P-type ion transporter activity 1/696 25/18639 0.04 1.07120689655172 0.614042188364354 0.794356164312616 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/696 25/18639 0.04 1.07120689655172 0.614042188364354 0.794356164312616 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/696 25/18639 0.04 1.07120689655172 0.614042188364354 0.794356164312616 GO:0019211 phosphatase activator activity 1/696 25/18639 0.04 1.07120689655172 0.614042188364354 0.794356164312616 GO:0042974 nuclear retinoic acid receptor binding 1/696 25/18639 0.04 1.07120689655172 0.614042188364354 0.794356164312616 GO:0120515 fatty acid-CoA ligase activity 1/696 25/18639 0.04 1.07120689655172 0.614042188364354 0.794356164312616 GO:0140358 P-type transmembrane transporter activity 1/696 25/18639 0.04 1.07120689655172 0.614042188364354 0.794356164312616 GO:0017124 SH3 domain binding 4/696 115/18639 0.0347826086956522 0.931484257871064 0.626961063162984 0.801365317733257 GO:0001637 G protein-coupled chemoattractant receptor activity 1/696 26/18639 0.0384615384615385 1.03000663129973 0.628473618304098 0.801365317733257 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/696 26/18639 0.0384615384615385 1.03000663129973 0.628473618304098 0.801365317733257 GO:0004529 DNA exonuclease activity 1/696 26/18639 0.0384615384615385 1.03000663129973 0.628473618304098 0.801365317733257 GO:0004950 chemokine receptor activity 1/696 26/18639 0.0384615384615385 1.03000663129973 0.628473618304098 0.801365317733257 GO:0005160 transforming growth factor beta receptor binding 1/696 26/18639 0.0384615384615385 1.03000663129973 0.628473618304098 0.801365317733257 GO:0005227 calcium-activated cation channel activity 1/696 26/18639 0.0384615384615385 1.03000663129973 0.628473618304098 0.801365317733257 GO:0034237 protein kinase A regulatory subunit binding 1/696 26/18639 0.0384615384615385 1.03000663129973 0.628473618304098 0.801365317733257 GO:0043548 phosphatidylinositol 3-kinase binding 1/696 26/18639 0.0384615384615385 1.03000663129973 0.628473618304098 0.801365317733257 GO:0052742 phosphatidylinositol kinase activity 1/696 26/18639 0.0384615384615385 1.03000663129973 0.628473618304098 0.801365317733257 GO:0120014 phospholipid transfer activity 1/696 26/18639 0.0384615384615385 1.03000663129973 0.628473618304098 0.801365317733257 GO:0019001 guanyl nucleotide binding 14/696 400/18639 0.035 0.937306034482759 0.636268310746835 0.809194288570096 GO:0032561 guanyl ribonucleotide binding 14/696 400/18639 0.035 0.937306034482759 0.636268310746835 0.809194288570096 GO:0004364 glutathione transferase activity 1/696 27/18639 0.037037037037037 0.991858237547893 0.642366185953609 0.810327885418455 GO:0008266 poly(U) RNA binding 1/696 27/18639 0.037037037037037 0.991858237547893 0.642366185953609 0.810327885418455 GO:0008320 protein transmembrane transporter activity 1/696 27/18639 0.037037037037037 0.991858237547893 0.642366185953609 0.810327885418455 GO:0008395 steroid hydroxylase activity 1/696 27/18639 0.037037037037037 0.991858237547893 0.642366185953609 0.810327885418455 GO:0016405 CoA-ligase activity 1/696 27/18639 0.037037037037037 0.991858237547893 0.642366185953609 0.810327885418455 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/696 27/18639 0.037037037037037 0.991858237547893 0.642366185953609 0.810327885418455 GO:0008408 3'-5' exonuclease activity 2/696 58/18639 0.0344827586206897 0.923454221165279 0.642959549166382 0.810327885418455 GO:0003730 mRNA 3'-UTR binding 9/696 262/18639 0.0343511450381679 0.919929586733351 0.647736410904429 0.815297567393219 GO:0001786 phosphatidylserine binding 2/696 59/18639 0.0338983050847458 0.907802454704851 0.652213871564218 0.818002174276065 GO:0008527 taste receptor activity 1/696 28/18639 0.0357142857142857 0.956434729064039 0.655739984286743 0.818002174276065 GO:0036408 histone H3K14 acetyltransferase activity 1/696 28/18639 0.0357142857142857 0.956434729064039 0.655739984286743 0.818002174276065 GO:0050698 proteoglycan sulfotransferase activity 1/696 28/18639 0.0357142857142857 0.956434729064039 0.655739984286743 0.818002174276065 GO:0051537 2 iron, 2 sulfur cluster binding 1/696 28/18639 0.0357142857142857 0.956434729064039 0.655739984286743 0.818002174276065 GO:0051959 dynein light intermediate chain binding 1/696 28/18639 0.0357142857142857 0.956434729064039 0.655739984286743 0.818002174276065 GO:0141052 histone H3 demethylase activity 1/696 28/18639 0.0357142857142857 0.956434729064039 0.655739984286743 0.818002174276065 GO:0005516 calmodulin binding 7/696 207/18639 0.0338164251207729 0.905609695152424 0.658044485259516 0.819831218578098 GO:0098531 ligand-modulated transcription factor activity 2/696 60/18639 0.0333333333333333 0.892672413793103 0.661276124092014 0.822809223106858 GO:0072341 modified amino acid binding 3/696 91/18639 0.032967032967033 0.882862826828344 0.665670101681359 0.82544644242588 GO:0005416 amino acid:monoatomic cation symporter activity 1/696 29/18639 0.0344827586206897 0.923454221165279 0.668614358094514 0.82544644242588 GO:0010484 histone H3 acetyltransferase activity 1/696 29/18639 0.0344827586206897 0.923454221165279 0.668614358094514 0.82544644242588 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/696 29/18639 0.0344827586206897 0.923454221165279 0.668614358094514 0.82544644242588 GO:0099604 ligand-gated calcium channel activity 1/696 29/18639 0.0344827586206897 0.923454221165279 0.668614358094514 0.82544644242588 GO:0106222 lncRNA binding 1/696 29/18639 0.0344827586206897 0.923454221165279 0.668614358094514 0.82544644242588 GO:0015026 coreceptor activity 2/696 61/18639 0.0327868852459016 0.878038439796495 0.67014772524146 0.82544644242588 GO:0016836 hydro-lyase activity 2/696 61/18639 0.0327868852459016 0.878038439796495 0.67014772524146 0.82544644242588 GO:0052689 carboxylic ester hydrolase activity 3/696 92/18639 0.0326086956521739 0.873266491754123 0.672893525376913 0.827785997256127 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/696 30/18639 0.0333333333333333 0.892672413793103 0.681007931805757 0.831492830594295 GO:0022839 monoatomic ion-gated channel activity 1/696 30/18639 0.0333333333333333 0.892672413793103 0.681007931805757 0.831492830594295 GO:0032452 histone demethylase activity 1/696 30/18639 0.0333333333333333 0.892672413793103 0.681007931805757 0.831492830594295 GO:0043995 histone H4K5 acetyltransferase activity 1/696 30/18639 0.0333333333333333 0.892672413793103 0.681007931805757 0.831492830594295 GO:0043996 histone H4K8 acetyltransferase activity 1/696 30/18639 0.0333333333333333 0.892672413793103 0.681007931805757 0.831492830594295 GO:0043997 histone H4K12 acetyltransferase activity 1/696 30/18639 0.0333333333333333 0.892672413793103 0.681007931805757 0.831492830594295 GO:1901682 sulfur compound transmembrane transporter activity 2/696 63/18639 0.0317460317460317 0.850164203612479 0.687325442355536 0.838159953396153 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/696 31/18639 0.032258064516129 0.863876529477197 0.692938636274733 0.841855883573527 GO:0016878 acid-thiol ligase activity 1/696 31/18639 0.032258064516129 0.863876529477197 0.692938636274733 0.841855883573527 GO:0140457 protein demethylase activity 1/696 31/18639 0.032258064516129 0.863876529477197 0.692938636274733 0.841855883573527 GO:0008276 protein methyltransferase activity 3/696 95/18639 0.0315789473684211 0.845689655172414 0.693872250960215 0.841944244961651 GO:0003924 GTPase activity 11/696 331/18639 0.0332326283987915 0.889975518283154 0.695839480529472 0.843285021013412 GO:0160215 deacylase activity 2/696 65/18639 0.0307692307692308 0.824005305039788 0.703761360111878 0.85157776565312 GO:0022884 macromolecule transmembrane transporter activity 1/696 32/18639 0.03125 0.836880387931034 0.704423734574002 0.85157776565312 GO:0008017 microtubule binding 9/696 276/18639 0.0326086956521739 0.873266491754123 0.707025644960291 0.852927456910162 GO:0030594 neurotransmitter receptor activity 3/696 97/18639 0.0309278350515464 0.828252755065766 0.707284424901985 0.852927456910162 GO:0008170 N-methyltransferase activity 3/696 98/18639 0.0306122448979592 0.819801196340605 0.713819636741735 0.857523639949962 GO:0042626 ATPase-coupled transmembrane transporter activity 3/696 98/18639 0.0306122448979592 0.819801196340605 0.713819636741735 0.857523639949962 GO:0035591 signaling adaptor activity 4/696 129/18639 0.0310077519379845 0.830392943063352 0.714492688318736 0.857523639949962 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/696 33/18639 0.0303030303030303 0.811520376175549 0.715479846829416 0.857523639949962 GO:0019239 deaminase activity 1/696 33/18639 0.0303030303030303 0.811520376175549 0.715479846829416 0.857523639949962 GO:0008173 RNA methyltransferase activity 2/696 67/18639 0.0298507462686567 0.799408131755018 0.719471775894025 0.861252627691991 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/696 34/18639 0.0294117647058824 0.787652129817444 0.726122974132798 0.861897126088332 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/696 34/18639 0.0294117647058824 0.787652129817444 0.726122974132798 0.861897126088332 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/696 34/18639 0.0294117647058824 0.787652129817444 0.726122974132798 0.861897126088332 GO:0051427 hormone receptor binding 1/696 34/18639 0.0294117647058824 0.787652129817444 0.726122974132798 0.861897126088332 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/696 34/18639 0.0294117647058824 0.787652129817444 0.726122974132798 0.861897126088332 GO:0043130 ubiquitin binding 3/696 100/18639 0.03 0.803405172413793 0.726551072105915 0.861897126088332 GO:0003777 microtubule motor activity 2/696 68/18639 0.0294117647058824 0.787652129817444 0.727060459123593 0.861897126088332 GO:0140223 general transcription initiation factor activity 2/696 68/18639 0.0294117647058824 0.787652129817444 0.727060459123593 0.861897126088332 GO:0005179 hormone activity 4/696 132/18639 0.0303030303030303 0.811520376175549 0.731144780430065 0.865689582639955 GO:0016279 protein-lysine N-methyltransferase activity 2/696 69/18639 0.0289855072463768 0.77623688155922 0.734474583799169 0.868580583984991 GO:0005343 organic acid:sodium symporter activity 1/696 35/18639 0.0285714285714286 0.765147783251231 0.736368521566476 0.868719437987953 GO:0010485 histone H4 acetyltransferase activity 1/696 35/18639 0.0285714285714286 0.765147783251231 0.736368521566476 0.868719437987953 GO:0015081 sodium ion transmembrane transporter activity 5/696 164/18639 0.0304878048780488 0.816468671152229 0.737569770592482 0.869088235710177 GO:0016278 lysine N-methyltransferase activity 2/696 70/18639 0.0285714285714286 0.765147783251231 0.741716583542859 0.871873580174178 GO:0016782 transferase activity, transferring sulphur-containing groups 2/696 70/18639 0.0285714285714286 0.765147783251231 0.741716583542859 0.871873580174178 GO:0004190 aspartic-type endopeptidase activity 1/696 36/18639 0.0277777777777778 0.74389367816092 0.746231320372632 0.873951377120001 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/696 36/18639 0.0277777777777778 0.74389367816092 0.746231320372632 0.873951377120001 GO:0005484 SNAP receptor activity 1/696 36/18639 0.0277777777777778 0.74389367816092 0.746231320372632 0.873951377120001 GO:0015297 antiporter activity 4/696 135/18639 0.0296296296296296 0.793486590038314 0.747058641382742 0.873951377120001 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 5/696 167/18639 0.029940119760479 0.801801569275243 0.751762083444588 0.876820316739521 GO:0016874 ligase activity 5/696 167/18639 0.029940119760479 0.801801569275243 0.751762083444588 0.876820316739521 GO:0016779 nucleotidyltransferase activity 4/696 136/18639 0.0294117647058824 0.787652129817444 0.752200660270407 0.876820316739521 GO:0030280 structural constituent of skin epidermis 1/696 37/18639 0.027027027027027 0.72378844361603 0.755725649299184 0.878532002024883 GO:0070001 aspartic-type peptidase activity 1/696 37/18639 0.027027027027027 0.72378844361603 0.755725649299184 0.878532002024883 GO:0016247 channel regulator activity 5/696 168/18639 0.0297619047619048 0.797028940886699 0.75636395266355 0.878532002024883 GO:0016755 aminoacyltransferase activity 16/696 496/18639 0.032258064516129 0.863876529477197 0.760691661157339 0.881669404021039 GO:0000149 SNARE binding 3/696 106/18639 0.0283018867924528 0.757929407937541 0.762085573598573 0.881669404021039 GO:0004497 monooxygenase activity 3/696 106/18639 0.0283018867924528 0.757929407937541 0.762085573598573 0.881669404021039 GO:0000146 microfilament motor activity 1/696 38/18639 0.0263157894736842 0.704741379310345 0.764865255152736 0.881669404021039 GO:0005109 frizzled binding 1/696 38/18639 0.0263157894736842 0.704741379310345 0.764865255152736 0.881669404021039 GO:0042162 telomeric DNA binding 1/696 38/18639 0.0263157894736842 0.704741379310345 0.764865255152736 0.881669404021039 GO:0141108 transporter regulator activity 5/696 170/18639 0.0294117647058824 0.787652129817444 0.765375586926239 0.881669404021039 GO:0035064 methylated histone binding 2/696 74/18639 0.027027027027027 0.72378844361603 0.769014004911187 0.884818466827225 GO:0004713 protein tyrosine kinase activity 4/696 140/18639 0.0285714285714286 0.765147783251231 0.771966633607029 0.887171994909135 GO:0015631 tubulin binding 12/696 385/18639 0.0311688311688312 0.834706672637707 0.778121645726681 0.888415589793934 GO:0051536 iron-sulfur cluster binding 2/696 76/18639 0.0263157894736842 0.704741379310345 0.781697064909528 0.888415589793934 GO:0140034 methylation-dependent protein binding 2/696 76/18639 0.0263157894736842 0.704741379310345 0.781697064909528 0.888415589793934 GO:0004177 aminopeptidase activity 1/696 40/18639 0.025 0.669504310344828 0.782132743162145 0.888415589793934 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/696 40/18639 0.025 0.669504310344828 0.782132743162145 0.888415589793934 GO:0032451 demethylase activity 1/696 40/18639 0.025 0.669504310344828 0.782132743162145 0.888415589793934 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/696 40/18639 0.025 0.669504310344828 0.782132743162145 0.888415589793934 GO:0061791 GTPase motor activity 1/696 40/18639 0.025 0.669504310344828 0.782132743162145 0.888415589793934 GO:0071949 FAD binding 1/696 40/18639 0.025 0.669504310344828 0.782132743162145 0.888415589793934 GO:1990606 membrane scission GTPase motor activity 1/696 40/18639 0.025 0.669504310344828 0.782132743162145 0.888415589793934 GO:0051540 metal cluster binding 2/696 77/18639 0.025974025974026 0.695588893864756 0.787806579029173 0.889412370241614 GO:0005216 monoatomic ion channel activity 14/696 448/18639 0.03125 0.836880387931034 0.788833921265211 0.889412370241614 GO:0001727 lipid kinase activity 1/696 41/18639 0.024390243902439 0.653174936921783 0.790285633680944 0.889412370241614 GO:0004812 aminoacyl-tRNA ligase activity 1/696 41/18639 0.024390243902439 0.653174936921783 0.790285633680944 0.889412370241614 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/696 41/18639 0.024390243902439 0.653174936921783 0.790285633680944 0.889412370241614 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/696 41/18639 0.024390243902439 0.653174936921783 0.790285633680944 0.889412370241614 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/696 41/18639 0.024390243902439 0.653174936921783 0.790285633680944 0.889412370241614 GO:0140318 protein transporter activity 1/696 41/18639 0.024390243902439 0.653174936921783 0.790285633680944 0.889412370241614 GO:0046873 metal ion transmembrane transporter activity 14/696 450/18639 0.0311111111111111 0.83316091954023 0.794059795696191 0.89263273585158 GO:0031492 nucleosomal DNA binding 1/696 42/18639 0.0238095238095238 0.63762315270936 0.798133853863655 0.896182444407181 GO:0000049 tRNA binding 2/696 80/18639 0.025 0.669504310344828 0.805239848410074 0.901560206335844 GO:0008375 acetylglucosaminyltransferase activity 1/696 43/18639 0.0232558139534884 0.622794707297514 0.805688773351255 0.901560206335844 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/696 43/18639 0.0232558139534884 0.622794707297514 0.805688773351255 0.901560206335844 GO:0001223 transcription coactivator binding 1/696 44/18639 0.0227272727272727 0.608640282131661 0.812961338082785 0.906586304042147 GO:0016790 thiolester hydrolase activity 1/696 44/18639 0.0227272727272727 0.608640282131661 0.812961338082785 0.906586304042147 GO:0043014 alpha-tubulin binding 1/696 44/18639 0.0227272727272727 0.608640282131661 0.812961338082785 0.906586304042147 GO:0016741 transferase activity, transferring one-carbon groups 6/696 215/18639 0.027906976744186 0.747353648757017 0.818124394594585 0.9113048495598 GO:0005261 monoatomic cation channel activity 10/696 341/18639 0.0293255131964809 0.785342299524724 0.82335529178537 0.916088140348227 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/696 46/18639 0.0217391304347826 0.582177661169415 0.826701162544787 0.917279865143305 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/696 46/18639 0.0217391304347826 0.582177661169415 0.826701162544787 0.917279865143305 GO:0003774 cytoskeletal motor activity 4/696 153/18639 0.0261437908496732 0.700135226504395 0.827712276399919 0.917279865143305 GO:0008234 cysteine-type peptidase activity 5/696 187/18639 0.0267379679144385 0.716047390743131 0.831986436703153 0.917279865143305 GO:0005504 fatty acid binding 1/696 47/18639 0.0212765957446809 0.56979090242113 0.833188334645514 0.917279865143305 GO:0061749 forked DNA-dependent helicase activity 1/696 47/18639 0.0212765957446809 0.56979090242113 0.833188334645514 0.917279865143305 GO:0140359 ABC-type transporter activity 1/696 47/18639 0.0212765957446809 0.56979090242113 0.833188334645514 0.917279865143305 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/696 47/18639 0.0212765957446809 0.56979090242113 0.833188334645514 0.917279865143305 GO:0046943 carboxylic acid transmembrane transporter activity 5/696 188/18639 0.0265957446808511 0.712238628026412 0.83537315634973 0.917279865143305 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/696 86/18639 0.0232558139534884 0.622794707297514 0.836324645308536 0.917279865143305 GO:0005342 organic acid transmembrane transporter activity 5/696 189/18639 0.0264550264550265 0.708470169677066 0.838703908569346 0.917279865143305 GO:0009378 four-way junction helicase activity 1/696 48/18639 0.0208333333333333 0.55792025862069 0.839433005422554 0.917279865143305 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/696 48/18639 0.0208333333333333 0.55792025862069 0.839433005422554 0.917279865143305 GO:0032266 phosphatidylinositol-3-phosphate binding 1/696 48/18639 0.0208333333333333 0.55792025862069 0.839433005422554 0.917279865143305 GO:0036121 double-stranded DNA helicase activity 1/696 48/18639 0.0208333333333333 0.55792025862069 0.839433005422554 0.917279865143305 GO:0043138 3'-5' DNA helicase activity 1/696 48/18639 0.0208333333333333 0.55792025862069 0.839433005422554 0.917279865143305 GO:0005267 potassium channel activity 3/696 124/18639 0.0241935483870968 0.647907397107898 0.846651992457467 0.924135768552905 GO:0015079 potassium ion transmembrane transporter activity 4/696 160/18639 0.025 0.669504310344828 0.852732592242544 0.928699861039208 GO:0099106 ion channel regulator activity 4/696 160/18639 0.025 0.669504310344828 0.852732592242544 0.928699861039208 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/696 91/18639 0.021978021978022 0.588575217885563 0.858724947077821 0.934185760002346 GO:0019787 ubiquitin-like protein transferase activity 14/696 479/18639 0.0292275574112735 0.78271902670794 0.859684108986606 0.934190065098779 GO:0004842 ubiquitin-protein transferase activity 13/696 449/18639 0.0289532293986637 0.775372475232317 0.860740105953886 0.934299471279579 GO:0030159 signaling receptor complex adaptor activity 1/696 52/18639 0.0192307692307692 0.515003315649867 0.862162739232587 0.934806162937328 GO:0005544 calcium-dependent phospholipid binding 1/696 53/18639 0.0188679245283019 0.50528627195836 0.867324128025513 0.935218299017587 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/696 53/18639 0.0188679245283019 0.50528627195836 0.867324128025513 0.935218299017587 GO:0017046 peptide hormone binding 1/696 53/18639 0.0188679245283019 0.50528627195836 0.867324128025513 0.935218299017587 GO:0051018 protein kinase A binding 1/696 53/18639 0.0188679245283019 0.50528627195836 0.867324128025513 0.935218299017587 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/696 53/18639 0.0188679245283019 0.50528627195836 0.867324128025513 0.935218299017587 GO:0042562 hormone binding 2/696 94/18639 0.0212765957446809 0.56979090242113 0.870783691125664 0.937474810892054 GO:0005262 calcium channel activity 3/696 131/18639 0.0229007633587786 0.613286391155567 0.871719321071387 0.937474810892054 GO:0003925 G protein activity 1/696 54/18639 0.0185185185185185 0.495929118773946 0.872292513202218 0.937474810892054 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/696 56/18639 0.0178571428571429 0.47821736453202 0.881678832471767 0.946185325384867 GO:0008168 methyltransferase activity 5/696 204/18639 0.0245098039215686 0.65637677484787 0.882332327966256 0.946185325384867 GO:0005249 voltage-gated potassium channel activity 2/696 98/18639 0.0204081632653061 0.546534130893737 0.885390919909272 0.948425322750568 GO:0017116 single-stranded DNA helicase activity 1/696 58/18639 0.0172413793103448 0.46172711058264 0.890376188697599 0.952722004974017 GO:0061659 ubiquitin-like protein ligase activity 10/696 372/18639 0.0268817204301075 0.719897107897664 0.892249764485291 0.953683354826901 GO:0004879 nuclear receptor activity 1/696 59/18639 0.0169491525423729 0.453901227352425 0.894482435544726 0.955026006509544 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/696 60/18639 0.0166666666666667 0.446336206896552 0.898435084891382 0.957156332269904 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/696 60/18639 0.0166666666666667 0.446336206896552 0.898435084891382 0.957156332269904 GO:0061630 ubiquitin protein ligase activity 9/696 353/18639 0.0254957507082153 0.682780599785093 0.914460201463014 0.973168745408952 GO:0015085 calcium ion transmembrane transporter activity 3/696 147/18639 0.0204081632653061 0.546534130893737 0.915861232744568 0.973600310461073 GO:1902936 phosphatidylinositol bisphosphate binding 2/696 111/18639 0.018018018018018 0.482525629077353 0.922943795889042 0.980064095960351 GO:0005548 phospholipid transporter activity 1/696 68/18639 0.0147058823529412 0.393826064908722 0.925172271138172 0.981364947042442 GO:0098960 postsynaptic neurotransmitter receptor activity 1/696 69/18639 0.0144927536231884 0.38811844077961 0.927976648893157 0.983273198935545 GO:0035401 histone H3Y41 kinase activity 2/696 115/18639 0.0173913043478261 0.465742128935532 0.931938663924816 0.985336230614562 GO:0140801 histone H2AXY142 kinase activity 2/696 115/18639 0.0173913043478261 0.465742128935532 0.931938663924816 0.985336230614562 GO:0004674 protein serine/threonine kinase activity 11/696 433/18639 0.0254041570438799 0.68032770566218 0.934116068781741 0.985650650870869 GO:0000287 magnesium ion binding 5/696 230/18639 0.0217391304347826 0.582177661169415 0.934251690549382 0.985650650870869 GO:0003684 damaged DNA binding 1/696 74/18639 0.0135135135135135 0.361894221808015 0.940500479542234 0.991173996758949 GO:0030971 receptor tyrosine kinase binding 1/696 81/18639 0.0123456790123457 0.330619412515964 0.954466462356557 0.999680268806859 GO:0022836 gated channel activity 7/696 318/18639 0.0220125786163522 0.589500650618087 0.955159810434292 0.999680268806859 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/696 130/18639 0.0153846153846154 0.412002652519894 0.957572553737079 0.999680268806859 GO:0045182 translation regulator activity 8/696 356/18639 0.0224719101123595 0.60180162727625 0.957988142050634 0.999680268806859 GO:0005543 phospholipid binding 12/696 497/18639 0.0241448692152917 0.646603760493998 0.962065951915869 0.999680268806859 GO:0050660 flavin adenine dinucleotide binding 1/696 86/18639 0.0116279069767442 0.311397353648757 0.962388829759372 0.999680268806859 GO:1901981 phosphatidylinositol phosphate binding 3/696 185/18639 0.0162162162162162 0.434273066169618 0.97096732291278 0.999680268806859 GO:0022843 voltage-gated monoatomic cation channel activity 2/696 143/18639 0.013986013986014 0.374547865927176 0.972055468501738 0.999680268806859 GO:0051020 GTPase binding 6/696 315/18639 0.019047619047619 0.510098522167488 0.979029738948144 0.999680268806859 GO:0015171 amino acid transmembrane transporter activity 1/696 102/18639 0.00980392156862745 0.262550709939148 0.979605316757057 0.999680268806859 GO:0031267 small GTPase binding 5/696 283/18639 0.0176678445229682 0.473147922505179 0.982076405406864 0.999680268806859 GO:0004677 DNA-dependent protein kinase activity 4/696 246/18639 0.016260162601626 0.435449957947855 0.983411960943446 0.999680268806859 GO:0004843 cysteine-type deubiquitinase activity 1/696 108/18639 0.00925925925925926 0.247964559386973 0.983790048635225 0.999680268806859 GO:0101005 deubiquitinase activity 1/696 115/18639 0.00869565217391304 0.232871064467766 0.987601124351077 0.999680268806859 GO:0005244 voltage-gated monoatomic ion channel activity 2/696 173/18639 0.0115606936416185 0.309597368945585 0.989578462461968 0.999680268806859 GO:0022832 voltage-gated channel activity 2/696 175/18639 0.0114285714285714 0.306059113300493 0.990251094287242 0.999680268806859 GO:0016757 glycosyltransferase activity 4/696 267/18639 0.0149812734082397 0.401201084850833 0.990778154729591 0.999680268806859 GO:0019783 ubiquitin-like protein peptidase activity 1/696 127/18639 0.0078740157480315 0.210867499321206 0.99217046252379 0.999680268806859 GO:0001653 peptide receptor activity 1/696 128/18639 0.0078125 0.209220096982759 0.992464831478168 0.999680268806859 GO:0035091 phosphatidylinositol binding 4/696 284/18639 0.0140845070422535 0.377185526954832 0.994332692010825 0.999680268806859 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/696 243/18639 0.0123456790123457 0.330619412515964 0.994932934769664 0.999680268806859 GO:0140101 catalytic activity, acting on a tRNA 1/696 139/18639 0.00719424460431655 0.192663110890598 0.995057371807695 0.999680268806859 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0004711 ribosomal protein S6 kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0035175 histone H3S10 kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0035979 histone H2AXS139 kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0044022 histone H3S28 kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0044023 histone H4S1 kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0044024 histone H2AS1 kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0044025 histone H2BS14 kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0072354 histone H3T3 kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0072371 histone H2AS121 kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0140823 histone H2BS36 kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0140855 histone H3S57 kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0140995 histone H2A kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0140997 histone H4 kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0140998 histone H2B kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:1990244 histone H2AT120 kinase activity 3/696 245/18639 0.0122448979591837 0.327920478536242 0.995238513140195 0.999680268806859 GO:0140857 histone H3T45 kinase activity 3/696 246/18639 0.0121951219512195 0.326587468460892 0.995384519957438 0.999680268806859 GO:0035402 histone H3T11 kinase activity 3/696 247/18639 0.0121457489878543 0.32526525198939 0.995526177306511 0.999680268806859 GO:0035403 histone H3T6 kinase activity 3/696 247/18639 0.0121457489878543 0.32526525198939 0.995526177306511 0.999680268806859 GO:0004679 AMP-activated protein kinase activity 3/696 248/18639 0.0120967741935484 0.323953698553949 0.995663609902547 0.999680268806859 GO:0008194 UDP-glycosyltransferase activity 1/696 145/18639 0.00689655172413793 0.184690844233056 0.9960733759986 0.999680268806859 GO:0141003 histone H2AX kinase activity 5/696 354/18639 0.0141242937853107 0.378251022793688 0.99737022277972 0.999680268806859 GO:0140996 histone H3 kinase activity 5/696 357/18639 0.0140056022408964 0.375072442770212 0.997583701125638 0.999680268806859 GO:0035173 histone kinase activity 5/696 360/18639 0.0138888888888889 0.37194683908046 0.997780415361789 0.999680268806859 GO:0106310 protein serine kinase activity 5/696 361/18639 0.0138504155124654 0.370916515426497 0.997842482111156 0.999680268806859 GO:0016758 hexosyltransferase activity 1/696 197/18639 0.0050761421319797 0.135939961491336 0.999467281870026 0.999680268806859 GO:0030371 translation repressor activity 3/696 329/18639 0.00911854103343465 0.244196101037627 0.999680268806859 0.999680268806859