ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	166/2658	495/18639	0.335353535353535	2.35163827895205	3.89979269564118e-28	4.81234418642121e-25
GO:0140297	DNA-binding transcription factor binding	144/2658	488/18639	0.295081967213115	2.06923731636014	1.11497647115587e-18	6.8794048270317e-16
GO:0004674	protein serine/threonine kinase activity	131/2658	433/18639	0.302540415704388	2.12153905504668	4.40297711174951e-18	1.8110912519663e-15
GO:0106310	protein serine kinase activity	115/2658	361/18639	0.318559556786704	2.23387192586432	7.01257566523465e-18	2.16337959272489e-15
GO:0019787	ubiquitin-like protein transferase activity	137/2658	479/18639	0.286012526096033	2.00563862825582	1.40522937421391e-16	3.46810609555992e-14
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	108/2658	349/18639	0.30945558739255	2.17003111113986	7.00001501121844e-16	1.43966975397393e-13
GO:0016755	aminoacyltransferase activity	138/2658	496/18639	0.278225806451613	1.95103491589602	1.29283616644047e-15	2.27908547055362e-13
GO:0031625	ubiquitin protein ligase binding	97/2658	302/18639	0.321192052980132	2.25233208257964	1.52181226480936e-15	2.34739541846844e-13
GO:0044389	ubiquitin-like protein ligase binding	101/2658	322/18639	0.313664596273292	2.19954642962298	2.29610124990518e-15	3.14820993598111e-13
GO:0004842	ubiquitin-protein transferase activity	127/2658	449/18639	0.282850779510022	1.98346714796362	4.68177743564703e-15	5.77731335558844e-13
GO:0003714	transcription corepressor activity	73/2658	204/18639	0.357843137254902	2.50934470853804	1.01861335439315e-14	1.14269898120104e-12
GO:0042393	histone binding	82/2658	247/18639	0.331983805668016	2.32800833478034	3.05768226015888e-14	3.14431659086339e-12
GO:0061659	ubiquitin-like protein ligase activity	106/2658	372/18639	0.28494623655914	1.99816136313988	5.27133316053478e-13	5.0037116308461e-11
GO:0035173	histone kinase activity	103/2658	360/18639	0.286111111111111	2.00632994732882	8.5474942110225e-13	7.53400561171555e-11
GO:0140996	histone H3 kinase activity	102/2658	357/18639	0.285714285714286	2.0035472428249	1.21164787144805e-12	9.96782315577933e-11
GO:0003713	transcription coactivator activity	80/2658	256/18639	0.3125	2.19137979683973	2.30622442650319e-12	1.77867558894059e-10
GO:0030695	GTPase regulator activity	126/2658	489/18639	0.257668711656442	1.80688002880527	8.41126914483194e-12	6.10559183807212e-10
GO:0060589	nucleoside-triphosphatase regulator activity	126/2658	490/18639	0.257142857142857	1.80319251854241	9.76632154781985e-12	6.69535599444983e-10
GO:0141003	histone H2AX kinase activity	99/2658	354/18639	0.279661016949153	1.96109920801928	1.03121935359897e-11	6.6974983281112e-10
GO:0016922	nuclear receptor binding	51/2658	137/18639	0.372262773722628	2.61046118864412	1.9211920323907e-11	1.18537548398506e-09
GO:0061630	ubiquitin protein ligase activity	98/2658	353/18639	0.277620396600567	1.94678953056357	2.07482627088366e-11	1.21920743727163e-09
GO:0035403	histone H3T6 kinase activity	74/2658	247/18639	0.299595141700405	2.10088557041153	1.38892468925174e-10	7.79060484789385e-09
GO:0070063	RNA polymerase binding	29/2658	59/18639	0.491525423728814	3.44678042621571	1.88698231334956e-10	1.01240703246668e-08
GO:0140857	histone H3T45 kinase activity	73/2658	246/18639	0.296747967479675	2.08092000220228	2.98484574336322e-10	1.53470818637926e-08
GO:0035402	histone H3T11 kinase activity	73/2658	247/18639	0.295546558704453	2.07249522486543	3.65439882928365e-10	1.78179566568817e-08
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	72/2658	243/18639	0.296296296296296	2.07775269626285	4.25115511517262e-10	1.78179566568817e-08
GO:0004679	AMP-activated protein kinase activity	73/2658	248/18639	0.294354838709677	2.06413838928129	4.46660150448351e-10	1.78179566568817e-08
GO:0004676	3-phosphoinositide-dependent protein kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0004711	ribosomal protein S6 kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0035175	histone H3S10 kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0035979	histone H2AXS139 kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0044022	histone H3S28 kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0044023	histone H4S1 kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0044024	histone H2AS1 kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0044025	histone H2BS14 kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0072354	histone H3T3 kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0072371	histone H2AS121 kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0072518	Rho-dependent protein serine/threonine kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0140823	histone H2BS36 kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0140855	histone H3S57 kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0140995	histone H2A kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0140997	histone H4 kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0140998	histone H2B kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:1990244	histone H2AT120 kinase activity	72/2658	245/18639	0.293877551020408	2.06079144976275	6.35324224394486e-10	1.78179566568817e-08
GO:0004677	DNA-dependent protein kinase activity	72/2658	246/18639	0.292682926829268	2.05241424874745	7.7470614855648e-10	2.12441641626377e-08
GO:0001221	transcription coregulator binding	42/2658	115/18639	0.365217391304348	2.56105604082834	2.20774969421047e-09	5.92252852751245e-08
GO:0031490	chromatin DNA binding	45/2658	128/18639	0.3515625	2.4653022714447	2.43827353615849e-09	6.40176498642463e-08
GO:0004386	helicase activity	51/2658	155/18639	0.329032258064516	2.30731085705964	3.03267246129399e-09	7.64574109691983e-08
GO:0140030	modification-dependent protein binding	55/2658	173/18639	0.317919075144509	2.22938060256527	3.03599119731825e-09	7.64574109691983e-08
GO:0001222	transcription corepressor binding	24/2658	49/18639	0.489795918367347	3.43465241627125	7.5962865635135e-09	1.87476352387513e-07
GO:0071889	14-3-3 protein binding	19/2658	33/18639	0.575757575757576	4.03745126205623	8.72240221291118e-09	2.11047928053576e-07
GO:0001098	basal transcription machinery binding	27/2658	60/18639	0.45	3.15558690744921	9.17911520492811e-09	2.13717512507194e-07
GO:0001099	basal RNA polymerase II transcription machinery binding	27/2658	60/18639	0.45	3.15558690744921	9.17911520492811e-09	2.13717512507194e-07
GO:0019207	kinase regulator activity	77/2658	287/18639	0.268292682926829	1.8813797280185	1.49548375891239e-08	3.41745733055165e-07
GO:0008094	ATP-dependent activity, acting on DNA	61/2658	210/18639	0.29047619047619	2.03693969687198	2.03926954954672e-08	4.57537931661936e-07
GO:0140693	molecular condensate scaffold activity	23/2658	48/18639	0.479166666666667	3.36011568848758	2.64614713671891e-08	5.83097422626989e-07
GO:0043175	RNA polymerase core enzyme binding	21/2658	42/18639	0.5	3.50620767494357	4.14751811052571e-08	8.97901289191004e-07
GO:0061775	cohesin loader activity	48/2658	153/18639	0.313725490196078	2.19997344310185	4.78077725159093e-08	1.01715157387297e-06
GO:0140658	ATP-dependent chromatin remodeler activity	49/2658	158/18639	0.310126582278481	2.17473640597766	5.23286713070939e-08	1.08348023095447e-06
GO:1990841	promoter-specific chromatin binding	28/2658	68/18639	0.411764705882353	2.88746514407117	5.26813726558088e-08	1.08348023095447e-06
GO:0000993	RNA polymerase II complex binding	19/2658	36/18639	0.527777777777778	3.70099699021821	5.95065926772347e-08	1.20378910432308e-06
GO:0140713	histone chaperone activity	50/2658	164/18639	0.304878048780488	2.13793150911193	7.04840561208006e-08	1.38395770201539e-06
GO:0051219	phosphoprotein binding	34/2658	93/18639	0.365591397849462	2.56367873006626	7.06558632309313e-08	1.38395770201539e-06
GO:0032452	histone demethylase activity	17/2658	30/18639	0.566666666666667	3.97370203160271	7.41236747272331e-08	1.42919710333446e-06
GO:0019902	phosphatase binding	55/2658	190/18639	0.289473684210526	2.02990970654628	1.12898977596018e-07	2.14334366697671e-06
GO:0005085	guanyl-nucleotide exchange factor activity	63/2658	230/18639	0.273913043478261	1.92079203062126	1.32244538913367e-07	2.47257213665294e-06
GO:0045309	protein phosphorylated amino acid binding	25/2658	59/18639	0.423728813559322	2.97136243639285	1.38600380480112e-07	2.55272939570834e-06
GO:0140457	protein demethylase activity	17/2658	31/18639	0.548387096774194	3.8455180950994	1.42282282111597e-07	2.58200494302516e-06
GO:0141052	histone H3 demethylase activity	16/2658	28/18639	0.571428571428571	4.00709448564979	1.54102232841282e-07	2.75597326559627e-06
GO:0019783	ubiquitin-like protein peptidase activity	41/2658	127/18639	0.322834645669291	2.26385062476671	1.86559883552406e-07	3.28878423290956e-06
GO:0000510	H3-H4 histone complex chaperone activity	46/2658	151/18639	0.304635761589404	2.13623249069409	2.37713598520729e-07	3.96403487262946e-06
GO:0140584	chromatin extrusion motor activity	46/2658	151/18639	0.304635761589404	2.13623249069409	2.37713598520729e-07	3.96403487262946e-06
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	46/2658	151/18639	0.304635761589404	2.13623249069409	2.37713598520729e-07	3.96403487262946e-06
GO:0140849	ATP-dependent H2AZ histone chaperone activity	46/2658	151/18639	0.304635761589404	2.13623249069409	2.37713598520729e-07	3.96403487262946e-06
GO:0015616	DNA translocase activity	46/2658	152/18639	0.302631578947368	2.12217832957111	2.94278976590759e-07	4.77816127780259e-06
GO:0140674	ATP-dependent histone chaperone activity	46/2658	152/18639	0.302631578947368	2.12217832957111	2.94278976590759e-07	4.77816127780259e-06
GO:0008234	cysteine-type peptidase activity	53/2658	187/18639	0.283422459893048	1.98747600825678	3.9917860865599e-07	6.39722601404535e-06
GO:0003689	DNA clamp loader activity	47/2658	160/18639	0.29375	2.05989700902935	5.77058234723992e-07	9.12935720063341e-06
GO:0001046	core promoter sequence-specific DNA binding	20/2658	44/18639	0.454545454545455	3.18746152267597	6.26975358635533e-07	9.79351382982591e-06
GO:0140033	acetylation-dependent protein binding	14/2658	24/18639	0.583333333333333	4.09057562076749	6.64218558449389e-07	1.02455712640818e-05
GO:0101005	deubiquitinase activity	37/2658	115/18639	0.321739130434783	2.25616841692021	7.97455870368589e-07	1.21488956053684e-05
GO:0001727	lipid kinase activity	19/2658	41/18639	0.463414634146341	3.24965589385014	8.26525288076435e-07	1.2438197627882e-05
GO:0003727	single-stranded RNA binding	31/2658	89/18639	0.348314606741573	2.44252669490451	9.01749071101293e-07	1.34067271534819e-05
GO:0051020	GTPase binding	77/2658	315/18639	0.244444444444444	1.71414597441685	9.25377500874142e-07	1.35942361437939e-05
GO:0140597	protein carrier chaperone	52/2658	188/18639	0.276595744680851	1.93960424571346	1.15727591703091e-06	1.6800923313131e-05
GO:0004843	cysteine-type deubiquitinase activity	35/2658	108/18639	0.324074074074074	2.2725420115375	1.29648837004906e-06	1.86031005655876e-05
GO:0019887	protein kinase regulator activity	65/2658	255/18639	0.254901960784314	1.78747842252025	1.38966680532173e-06	1.97109061812301e-05
GO:0005096	GTPase activator activity	68/2658	271/18639	0.250922509225092	1.75957285532223	1.47004525670517e-06	2.06140437133429e-05
GO:0140097	catalytic activity, acting on DNA	80/2658	336/18639	0.238095238095238	1.66962270235408	1.74499457322514e-06	2.41946438579755e-05
GO:0046332	SMAD binding	28/2658	79/18639	0.354430379746835	2.48541303540303	2.02042923512333e-06	2.77023297349132e-05
GO:0001784	phosphotyrosine residue binding	20/2658	47/18639	0.425531914893617	2.98400653186687	2.25970824166509e-06	3.06426370353266e-05
GO:0032451	demethylase activity	18/2658	40/18639	0.45	3.15558690744921	2.7288229462745e-06	3.64938285969419e-05
GO:0070577	lysine-acetylated histone binding	13/2658	23/18639	0.565217391304348	3.96353911080577	2.75034526703047e-06	3.64938285969419e-05
GO:0004715	non-membrane spanning protein tyrosine kinase activity	19/2658	45/18639	0.422222222222222	2.96079759217457	4.64681018777989e-06	6.10017422523445e-05
GO:0031491	nucleosome binding	26/2658	74/18639	0.351351351351351	2.4638216094198	5.57630825254705e-06	7.24333093015059e-05
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	12/2658	21/18639	0.571428571428571	4.00709448564979	5.7714472292531e-06	7.41871445926909e-05
GO:0004706	JUN kinase kinase kinase activity	11/2658	18/18639	0.611111111111111	4.28536493604214	5.85657149849103e-06	7.45052497849271e-05
GO:0035591	signaling adaptor activity	38/2658	129/18639	0.294573643410853	2.06567273872644	6.23792979288413e-06	7.85469935144798e-05
GO:0031267	small GTPase binding	68/2658	283/18639	0.240282685512367	1.68496199219903	7.30613246336434e-06	9.10683581797131e-05
GO:0046966	nuclear thyroid hormone receptor binding	14/2658	28/18639	0.5	3.50620767494357	7.7323758562786e-06	9.54175180664779e-05
GO:0031072	heat shock protein binding	38/2658	131/18639	0.290076335877863	2.03413575034894	9.27059204655115e-06	0.000113266441440041
GO:0004709	MAP kinase kinase kinase activity	13/2658	25/18639	0.52	3.64645598194131	9.44599034690306e-06	0.000114277961647827
GO:1990518	single-stranded 3'-5' DNA helicase activity	19/2658	47/18639	0.404255319148936	2.83480620527352	9.98562511359915e-06	0.000119633605729916
GO:0050321	tau-protein kinase activity	12/2658	22/18639	0.545454545454545	3.82495382721116	1.10460393826815e-05	0.000131065505752201
GO:0140104	molecular carrier activity	61/2658	249/18639	0.244979919678715	1.71790094916914	1.11923045530776e-05	0.000131536226842835
GO:0043138	3'-5' DNA helicase activity	19/2658	48/18639	0.395833333333333	2.77574774266366	1.43289457210931e-05	0.000166810556790839
GO:0050681	nuclear androgen receptor binding	13/2658	26/18639	0.5	3.50620767494357	1.64250657323378e-05	0.000189425524427148
GO:0003725	double-stranded RNA binding	25/2658	75/18639	0.333333333333333	2.33747178329571	2.38115243300438e-05	0.000272068713178463
GO:0016887	ATP hydrolysis activity	90/2658	417/18639	0.215827338129496	1.51347093882456	2.80122517972651e-05	0.000317129529521331
GO:0140566	histone reader activity	15/2658	35/18639	0.428571428571429	3.00532086423734	3.77205535087989e-05	0.000423156027544162
GO:0003724	RNA helicase activity	25/2658	77/18639	0.324675324675325	2.27675823048284	3.93876256096355e-05	0.000437876846867479
GO:0061749	forked DNA-dependent helicase activity	18/2658	47/18639	0.382978723404255	2.68560587868018	4.05731314524356e-05	0.0004470289661813
GO:0009931	calcium-dependent protein serine/threonine kinase activity	11/2658	21/18639	0.523809523809524	3.67316994517898	4.28709397538204e-05	0.000468165837665614
GO:0004721	phosphoprotein phosphatase activity	45/2658	175/18639	0.257142857142857	1.80319251854241	4.36970759456807e-05	0.000473001681727807
GO:0051019	mitogen-activated protein kinase binding	13/2658	28/18639	0.464285714285714	3.25576426959045	4.47147522090315e-05	0.000479808732399521
GO:0002039	p53 binding	23/2658	69/18639	0.333333333333333	2.33747178329571	4.97890864998984e-05	0.000529652868455816
GO:0009378	four-way junction helicase activity	18/2658	48/18639	0.375	2.62965575620767	5.63196428912411e-05	0.000585395790070564
GO:0036121	double-stranded DNA helicase activity	18/2658	48/18639	0.375	2.62965575620767	5.63196428912411e-05	0.000585395790070564
GO:0140789	histone phosphatase activity	37/2658	136/18639	0.272058823529412	1.90778947018988	5.64522682482959e-05	0.000585395790070564
GO:0008186	ATP-dependent activity, acting on RNA	25/2658	79/18639	0.316455696202532	2.21911878160985	6.35854065205907e-05	0.000653869930386741
GO:1990380	K48-linked deubiquitinase activity	10/2658	19/18639	0.526315789473684	3.69074492099323	9.17581675623451e-05	0.000931103369526908
GO:0019903	protein phosphatase binding	38/2658	144/18639	0.263888888888889	1.8504984951091	9.20539798073605e-05	0.000931103369526908
GO:0052742	phosphatidylinositol kinase activity	12/2658	26/18639	0.461538461538462	3.2364993922556	9.46425576236063e-05	0.000947881913765236
GO:0008140	cAMP response element binding protein binding	7/2658	10/18639	0.7	4.90869074492099	9.60172116861057e-05	0.000947881913765236
GO:0045322	unmethylated CpG binding	7/2658	10/18639	0.7	4.90869074492099	9.60172116861057e-05	0.000947881913765236
GO:0008276	protein methyltransferase activity	28/2658	95/18639	0.294736842105263	2.06681715575621	9.78903918185456e-05	0.000958704313524487
GO:0001217	DNA-binding transcription repressor activity	63/2658	278/18639	0.226618705035971	1.58914448576579	0.000100525533185587	0.000976759905126093
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	9/2658	16/18639	0.5625	3.94448363431151	0.000106237106193311	0.00102419210189489
GO:0008187	poly-pyrimidine tract binding	13/2658	30/18639	0.433333333333333	3.03871331828442	0.000108216346775747	0.00103518582884707
GO:0032182	ubiquitin-like protein binding	33/2658	120/18639	0.275	1.92841422121896	0.000110809532087813	0.00105183817381817
GO:0035198	miRNA binding	16/2658	42/18639	0.380952380952381	2.67139632376653	0.000116022753282211	0.00109291662252098
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	20/2658	60/18639	0.333333333333333	2.33747178329571	0.000151353722112673	0.0014049484888437
GO:0140938	histone H3 methyltransferase activity	17/2658	47/18639	0.361702127659574	2.53640555208684	0.000151424756090933	0.0014049484888437
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	34/2658	128/18639	0.265625	1.86267282731377	0.000183330267966166	0.00168828022888245
GO:0035035	histone acetyltransferase binding	11/2658	24/18639	0.458333333333333	3.2140237020316	0.000200704849269828	0.00183459099258495
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	60/2658	268/18639	0.223880597014925	1.56994373504936	0.000205836238544529	0.0018676611644408
GO:0019789	SUMO transferase activity	12/2658	28/18639	0.428571428571429	3.00532086423734	0.000226025883894232	0.00203588277901812
GO:0070717	poly-purine tract binding	13/2658	32/18639	0.40625	2.84879373589165	0.000237645937974606	0.00212503686565698
GO:0004713	protein tyrosine kinase activity	36/2658	140/18639	0.257142857142857	1.80319251854241	0.000242213913647522	0.00215030193842477
GO:0042054	histone methyltransferase activity	21/2658	67/18639	0.313432835820896	2.1979212290691	0.000277143602515767	0.0024428228964604
GO:0017116	single-stranded DNA helicase activity	19/2658	58/18639	0.327586206896552	2.29717054565268	0.000283438006953499	0.00246311620127195
GO:0061980	regulatory RNA binding	19/2658	58/18639	0.327586206896552	2.29717054565268	0.000283438006953499	0.00246311620127195
GO:0140463	chromatin-protein adaptor activity	18/2658	54/18639	0.333333333333333	2.33747178329571	0.000319074531530058	0.00275341239096567
GO:0140098	catalytic activity, acting on RNA	80/2658	387/18639	0.20671834625323	1.44959490436943	0.000328214003063108	0.00281261166513803
GO:1990782	protein tyrosine kinase binding	31/2658	117/18639	0.264957264957265	1.85799039185044	0.000362101844649776	0.00306645299348448
GO:0036002	pre-mRNA binding	19/2658	59/18639	0.322033898305085	2.25823545165857	0.000362805621595408	0.00306645299348448
GO:0004197	cysteine-type endopeptidase activity	25/2658	88/18639	0.284090909090909	1.99216345167248	0.000421435106436708	0.00350266287377925
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	8/2658	15/18639	0.533333333333333	3.73995485327314	0.000425769393084998	0.00350266287377925
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	8/2658	15/18639	0.533333333333333	3.73995485327314	0.000425769393084998	0.00350266287377925
GO:0061578	K63-linked deubiquitinase activity	8/2658	15/18639	0.533333333333333	3.73995485327314	0.000425769393084998	0.00350266287377925
GO:0004722	protein serine/threonine phosphatase activity	28/2658	103/18639	0.271844660194175	1.90628766793048	0.00043550875391679	0.00355905829359814
GO:0003678	DNA helicase activity	22/2658	74/18639	0.297297297297297	2.08477213104753	0.000460198663160055	0.0037360865153915
GO:0035014	phosphatidylinositol 3-kinase regulator activity	7/2658	12/18639	0.583333333333333	4.09057562076749	0.000486848647717229	0.00388149567233054
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	7/2658	12/18639	0.583333333333333	4.09057562076749	0.000486848647717229	0.00388149567233054
GO:0035925	mRNA 3'-UTR AU-rich region binding	12/2658	30/18639	0.4	2.80496613995485	0.000487546052845408	0.00388149567233054
GO:0004712	protein serine/threonine/tyrosine kinase activity	15/2658	43/18639	0.348837209302326	2.44619140112342	0.000572743015147124	0.00450168713816274
GO:0048156	tau protein binding	15/2658	43/18639	0.348837209302326	2.44619140112342	0.000572743015147124	0.00450168713816274
GO:0017124	SH3 domain binding	30/2658	115/18639	0.260869565217391	1.82932574344882	0.000592714940094257	0.00457131397547696
GO:0035401	histone H3Y41 kinase activity	30/2658	115/18639	0.260869565217391	1.82932574344882	0.000592714940094257	0.00457131397547696
GO:0140801	histone H2AXY142 kinase activity	30/2658	115/18639	0.260869565217391	1.82932574344882	0.000592714940094257	0.00457131397547696
GO:0043130	ubiquitin binding	27/2658	100/18639	0.27	1.89335214446953	0.00061338377415438	0.0047013389894814
GO:0010485	histone H4 acetyltransferase activity	13/2658	35/18639	0.371428571428571	2.60461141567236	0.000666128052003371	0.00507408651958123
GO:0003697	single-stranded DNA binding	31/2658	121/18639	0.256198347107438	1.79656922187191	0.000675888104376094	0.00511684613987791
GO:0005521	lamin binding	8/2658	16/18639	0.5	3.50620767494357	0.000745301679976687	0.00560794068958068
GO:0019209	kinase activator activity	36/2658	148/18639	0.243243243243243	1.70572265267525	0.000752035598124235	0.00562431471566852
GO:0140296	general transcription initiation factor binding	17/2658	53/18639	0.320754716981132	2.24926530090719	0.000766041150883725	0.00569454686861757
GO:0045296	cadherin binding	69/2658	334/18639	0.206586826347305	1.44867263216231	0.000826417846982179	0.00610658456991622
GO:0004532	RNA exonuclease activity	14/2658	40/18639	0.35	2.4543453724605	0.000834846451144388	0.00613214595662009
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	23/2658	82/18639	0.280487804878049	1.96689698838298	0.000854420813759564	0.00623878866378285
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	94/2658	484/18639	0.194214876033058	1.36191537787064	0.000954255060311011	0.00692676908484581
GO:0051087	protein-folding chaperone binding	33/2658	134/18639	0.246268656716418	1.72693810855429	0.00097346570441618	0.00702489286110857
GO:0008170	N-methyltransferase activity	26/2658	98/18639	0.26530612244898	1.86043672548026	0.0010179527739078	0.00727371663070282
GO:0001216	DNA-binding transcription activator activity	95/2658	491/18639	0.193482688391039	1.35678097401075	0.00101973498955558	0.00727371663070282
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	6/2658	10/18639	0.6	4.20744920993228	0.00104699842879641	0.00734088671099304
GO:0016303	1-phosphatidylinositol-3-kinase activity	6/2658	10/18639	0.6	4.20744920993228	0.00104699842879641	0.00734088671099304
GO:0051864	histone H3K36 demethylase activity	6/2658	10/18639	0.6	4.20744920993228	0.00104699842879641	0.00734088671099304
GO:0016279	protein-lysine N-methyltransferase activity	20/2658	69/18639	0.289855072463768	2.03258415938758	0.00116339697594481	0.00811091451025932
GO:0023023	MHC protein complex binding	13/2658	37/18639	0.351351351351351	2.4638216094198	0.00121890856658609	0.0084501863548721
GO:1990226	histone methyltransferase binding	8/2658	17/18639	0.470588235294118	3.29996016465277	0.00123252612463792	0.0084968560771128
GO:0140416	transcription regulator inhibitor activity	12/2658	33/18639	0.363636363636364	2.54996921814078	0.00132347007637933	0.00907312263473385
GO:0016278	lysine N-methyltransferase activity	20/2658	70/18639	0.285714285714286	2.0035472428249	0.00141386203234613	0.00958629531821498
GO:0097110	scaffold protein binding	20/2658	70/18639	0.285714285714286	2.0035472428249	0.00141386203234613	0.00958629531821498
GO:0008139	nuclear localization sequence binding	10/2658	25/18639	0.4	2.80496613995485	0.00143495054720547	0.00959090768015854
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	10/2658	25/18639	0.4	2.80496613995485	0.00143495054720547	0.00959090768015854
GO:0044183	protein folding chaperone	21/2658	75/18639	0.28	1.9634762979684	0.00144159032346113	0.00959090768015854
GO:0019210	kinase inhibitor activity	24/2658	90/18639	0.266666666666667	1.86997742663657	0.00144563114141774	0.00959090768015854
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	13/2658	38/18639	0.342105263157895	2.3989841986456	0.00161380051645857	0.0105967103579117
GO:0032454	histone H3K9 demethylase activity	7/2658	14/18639	0.5	3.50620767494357	0.00162299696729766	0.0105967103579117
GO:0061665	SUMO ligase activity	7/2658	14/18639	0.5	3.50620767494357	0.00162299696729766	0.0105967103579117
GO:0030971	receptor tyrosine kinase binding	22/2658	81/18639	0.271604938271605	1.90460663824095	0.00173284087045434	0.0107996244148518
GO:0033192	calmodulin-dependent protein phosphatase activity	22/2658	81/18639	0.271604938271605	1.90460663824095	0.00173284087045434	0.0107996244148518
GO:0140791	histone H2AXS140 phosphatase activity	22/2658	81/18639	0.271604938271605	1.90460663824095	0.00173284087045434	0.0107996244148518
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	22/2658	81/18639	0.271604938271605	1.90460663824095	0.00173284087045434	0.0107996244148518
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	22/2658	81/18639	0.271604938271605	1.90460663824095	0.00173284087045434	0.0107996244148518
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	22/2658	81/18639	0.271604938271605	1.90460663824095	0.00173284087045434	0.0107996244148518
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	22/2658	81/18639	0.271604938271605	1.90460663824095	0.00173284087045434	0.0107996244148518
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	22/2658	81/18639	0.271604938271605	1.90460663824095	0.00173284087045434	0.0107996244148518
GO:1990439	MAP kinase serine/threonine phosphatase activity	22/2658	81/18639	0.271604938271605	1.90460663824095	0.00173284087045434	0.0107996244148518
GO:0015631	tubulin binding	76/2658	385/18639	0.197402597402597	1.38426900413356	0.00177280117122401	0.010949282245779
GO:0030159	signaling receptor complex adaptor activity	16/2658	52/18639	0.307692307692308	2.15766626150373	0.00177460003983452	0.010949282245779
GO:0043021	ribonucleoprotein complex binding	40/2658	177/18639	0.225988700564972	1.58472663274285	0.00181031011717918	0.0111140432069607
GO:0030295	protein kinase activator activity	33/2658	139/18639	0.237410071942446	1.66481803270702	0.00187786432768894	0.0114717058434067
GO:0004143	ATP-dependent diacylglycerol kinase activity	6/2658	11/18639	0.545454545454545	3.82495382721116	0.00202571936319577	0.0122112888933516
GO:0070412	R-SMAD binding	10/2658	26/18639	0.384615384615385	2.69708282687967	0.002036734711826	0.0122112888933516
GO:0033549	MAP kinase phosphatase activity	22/2658	82/18639	0.268292682926829	1.8813797280185	0.00205492822457575	0.0122112888933516
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	15/2658	48/18639	0.3125	2.19137979683973	0.00205769425096764	0.0122112888933516
GO:0070034	telomerase RNA binding	9/2658	22/18639	0.409090909090909	2.86871537040837	0.00205830477294744	0.0122112888933516
GO:0140517	protein-RNA adaptor activity	9/2658	22/18639	0.409090909090909	2.86871537040837	0.00205830477294744	0.0122112888933516
GO:0000175	3'-5'-RNA exonuclease activity	12/2658	35/18639	0.342857142857143	2.40425669138987	0.00236575934012633	0.0138860061237831
GO:0001223	transcription coactivator binding	14/2658	44/18639	0.318181818181818	2.23122306587318	0.00237434950738917	0.0138860061237831
GO:0043014	alpha-tubulin binding	14/2658	44/18639	0.318181818181818	2.23122306587318	0.00237434950738917	0.0138860061237831
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	22/2658	83/18639	0.265060240963855	1.85871250237972	0.00242639524795812	0.0141234515848128
GO:0043539	protein serine/threonine kinase activator activity	20/2658	73/18639	0.273972602739726	1.92120968490058	0.00245694906669324	0.0142341556258191
GO:0005164	tumor necrosis factor receptor binding	11/2658	31/18639	0.354838709677419	2.48827641447608	0.00261394104580249	0.0150729123856087
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	23/2658	89/18639	0.258426966292135	1.81219722525173	0.00279261526959237	0.015954107604986
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	23/2658	89/18639	0.258426966292135	1.81219722525173	0.00279261526959237	0.015954107604986
GO:0008266	poly(U) RNA binding	10/2658	27/18639	0.37037037037037	2.59719087032857	0.00282617216664833	0.0160029549978425
GO:0016791	phosphatase activity	56/2658	273/18639	0.205128205128205	1.43844417433582	0.00284289336009216	0.0160029549978425
GO:0004860	protein kinase inhibitor activity	22/2658	84/18639	0.261904761904762	1.83658497258949	0.00285303897854567	0.0160029549978425
GO:0017018	myosin phosphatase activity	22/2658	84/18639	0.261904761904762	1.83658497258949	0.00285303897854567	0.0160029549978425
GO:0044013	histone H2B acetyltransferase activity	9/2658	23/18639	0.391304347826087	2.74398861517323	0.00295801598401491	0.0165167046347258
GO:0042826	histone deacetylase binding	30/2658	127/18639	0.236220472440945	1.65647606690247	0.00318553598566648	0.0177069883167227
GO:0140793	histone H2AXY142 phosphatase activity	23/2658	90/18639	0.255555555555556	1.79206170052671	0.00325501280612994	0.0180120439585845
GO:0140313	molecular sequestering activity	16/2658	55/18639	0.290909090909091	2.03997537451262	0.00335236824088567	0.0184679571841648
GO:0030515	snoRNA binding	11/2658	32/18639	0.34375	2.4105177765237	0.00347698880905346	0.0190693519572087
GO:0019208	phosphatase regulator activity	28/2658	117/18639	0.239316239316239	1.67818487005846	0.00352252241256032	0.0192335958278736
GO:0034452	dynactin binding	6/2658	12/18639	0.5	3.50620767494357	0.0035645900786743	0.0192925620924741
GO:0035259	nuclear glucocorticoid receptor binding	6/2658	12/18639	0.5	3.50620767494357	0.0035645900786743	0.0192925620924741
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	37/2658	167/18639	0.221556886227545	1.55364890985523	0.00373817366483592	0.020143695643701
GO:0036408	histone H3K14 acetyltransferase activity	10/2658	28/18639	0.357142857142857	2.50443405353112	0.00384185394685334	0.0206123816105088
GO:0019888	protein phosphatase regulator activity	26/2658	107/18639	0.242990654205607	1.70395139343052	0.00386849808928089	0.0206654832994486
GO:0140034	methylation-dependent protein binding	20/2658	76/18639	0.263157894736842	1.84537246049661	0.00408231638514764	0.0217137000830698
GO:0001091	RNA polymerase II general transcription initiation factor binding	9/2658	24/18639	0.375	2.62965575620767	0.00414126639535866	0.021932715587436
GO:0004708	MAP kinase kinase activity	7/2658	16/18639	0.4375	3.06793171557562	0.00416800286176699	0.0219799809035063
GO:0004402	histone acetyltransferase activity	13/2658	42/18639	0.30952380952381	2.1705095130603	0.00438560423614504	0.0230290877761829
GO:0061733	protein-lysine-acetyltransferase activity	14/2658	47/18639	0.297872340425532	2.08880457230681	0.00466233219546407	0.0243784658017062
GO:0051213	dioxygenase activity	23/2658	93/18639	0.247311827956989	1.73425325857424	0.00504404435772124	0.026263083280287
GO:0010484	histone H3 acetyltransferase activity	10/2658	29/18639	0.344827586206897	2.41807425858177	0.00512568210509466	0.0265760156205328
GO:0008135	translation factor activity, RNA binding	21/2658	83/18639	0.253012048192771	1.77422557045337	0.00542859512083738	0.0280288133017294
GO:0017025	TBP-class protein binding	9/2658	25/18639	0.36	2.52446952595937	0.00566356905994483	0.0288795215701319
GO:0017056	structural constituent of nuclear pore	9/2658	25/18639	0.36	2.52446952595937	0.00566356905994483	0.0288795215701319
GO:0042974	nuclear retinoic acid receptor binding	9/2658	25/18639	0.36	2.52446952595937	0.00566356905994483	0.0288795215701319
GO:0046975	histone H3K36 methyltransferase activity	6/2658	13/18639	0.461538461538462	3.2364993922556	0.00582706249703196	0.0294696521366289
GO:0140852	histone ubiquitin ligase activity	6/2658	13/18639	0.461538461538462	3.2364993922556	0.00582706249703196	0.0294696521366289
GO:0035613	RNA stem-loop binding	8/2658	21/18639	0.380952380952381	2.67139632376653	0.00608058488667307	0.0305017957323357
GO:0051010	microtubule plus-end binding	8/2658	21/18639	0.380952380952381	2.67139632376653	0.00608058488667307	0.0305017957323357
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	7/2658	17/18639	0.411764705882353	2.88746514407117	0.00622283657775734	0.0309636303909377
GO:0032183	SUMO binding	7/2658	17/18639	0.411764705882353	2.88746514407117	0.00622283657775734	0.0309636303909377
GO:0180051	translation factor activity	21/2658	84/18639	0.25	1.75310383747178	0.0062871138349346	0.0311578251899972
GO:0043995	histone H4K5 acetyltransferase activity	10/2658	30/18639	0.333333333333333	2.33747178329571	0.00672235455752231	0.0329181965237402
GO:0043996	histone H4K8 acetyltransferase activity	10/2658	30/18639	0.333333333333333	2.33747178329571	0.00672235455752231	0.0329181965237402
GO:0043997	histone H4K12 acetyltransferase activity	10/2658	30/18639	0.333333333333333	2.33747178329571	0.00672235455752231	0.0329181965237402
GO:0140767	enzyme-substrate adaptor activity	31/2658	139/18639	0.223021582733813	1.56391997011871	0.00678299901218942	0.0330838766049081
GO:0005154	epidermal growth factor receptor binding	11/2658	35/18639	0.314285714285714	2.20390196710738	0.0074890528980912	0.0363838239222226
GO:0008143	poly(A) binding	9/2658	26/18639	0.346153846153846	2.4273745441917	0.00758365783247836	0.0365556006456183
GO:0043548	phosphatidylinositol 3-kinase binding	9/2658	26/18639	0.346153846153846	2.4273745441917	0.00758365783247836	0.0365556006456183
GO:0015924	mannosyl-oligosaccharide mannosidase activity	5/2658	10/18639	0.5	3.50620767494357	0.00791944180871561	0.03719325122941
GO:0042975	peroxisome proliferator activated receptor binding	5/2658	10/18639	0.5	3.50620767494357	0.00791944180871561	0.03719325122941
GO:0099122	RNA polymerase II C-terminal domain binding	5/2658	10/18639	0.5	3.50620767494357	0.00791944180871561	0.03719325122941
GO:0140999	histone H3K4 trimethyltransferase activity	5/2658	10/18639	0.5	3.50620767494357	0.00791944180871561	0.03719325122941
GO:0030331	nuclear estrogen receptor binding	12/2658	40/18639	0.3	2.10372460496614	0.00800606090235926	0.03719325122941
GO:0140662	ATP-dependent protein folding chaperone	12/2658	40/18639	0.3	2.10372460496614	0.00800606090235926	0.03719325122941
GO:0004407	histone deacetylase activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0032931	histone H3K56 acetyltransferase activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0033558	protein lysine deacetylase activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0043992	histone H3K9 acetyltransferase activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0043993	histone H3K18 acetyltransferase activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0043994	histone H3K23 acetyltransferase activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0043999	histone H2AK5 acetyltransferase activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0044012	histone H2AK9 acetyltransferase activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0044014	histone H2BK5 acetyltransferase activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0044015	histone H2BK12 acetyltransferase activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0044016	histone H3K4 acetyltransferase activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0044017	histone H3K27 acetyltransferase activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0044018	histone H3K36 acetyltransferase activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0046972	histone H4K16 acetyltransferase activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0140035	ubiquitin-like protein reader activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0140908	histone H3K122 acetyltransferase activity	8/2658	22/18639	0.363636363636364	2.54996921814078	0.00837903066594488	0.03719325122941
GO:0032813	tumor necrosis factor receptor superfamily binding	14/2658	50/18639	0.28	1.9634762979684	0.00846953151838649	0.037460221841179
GO:0019992	diacylglycerol binding	6/2658	14/18639	0.428571428571429	3.00532086423734	0.00898011164433271	0.0394357927726212
GO:0034236	protein kinase A catalytic subunit binding	6/2658	14/18639	0.428571428571429	3.00532086423734	0.00898011164433271	0.0394357927726212
GO:0004725	protein tyrosine phosphatase activity	23/2658	98/18639	0.23469387755102	1.64577094946331	0.00979140499497647	0.0428460771765992
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	12/2658	41/18639	0.292682926829268	2.05241424874745	0.00988139520648642	0.0429353580450854
GO:0042287	MHC protein binding	12/2658	41/18639	0.292682926829268	2.05241424874745	0.00988139520648642	0.0429353580450854
GO:0001671	ATPase activator activity	9/2658	27/18639	0.333333333333333	2.33747178329571	0.00996240066539336	0.0431354470915628
GO:0003743	translation initiation factor activity	14/2658	51/18639	0.274509803921569	1.92497676271412	0.0101769840695037	0.043910483712474
GO:0042578	phosphoric ester hydrolase activity	68/2658	363/18639	0.18732782369146	1.31362050631495	0.0103274648053081	0.0444045002430322
GO:0051059	NF-kappaB binding	10/2658	32/18639	0.3125	2.19137979683973	0.0110431751872384	0.0473169381286535
GO:0042800	histone H3K4 methyltransferase activity	7/2658	19/18639	0.368421052631579	2.58352144469526	0.0124501476963646	0.0529775250252204
GO:0140036	ubiquitin-modified protein reader activity	7/2658	19/18639	0.368421052631579	2.58352144469526	0.0124501476963646	0.0529775250252204
GO:0070990	snRNP binding	5/2658	11/18639	0.454545454545455	3.18746152267597	0.0128308771799821	0.0538007560850878
GO:0140537	transcription regulator activator activity	5/2658	11/18639	0.454545454545455	3.18746152267597	0.0128308771799821	0.0538007560850878
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	5/2658	11/18639	0.454545454545455	3.18746152267597	0.0128308771799821	0.0538007560850878
GO:0046875	ephrin receptor binding	9/2658	28/18639	0.321428571428571	2.25399064817801	0.0128616070057544	0.0538007560850878
GO:0097718	disordered domain specific binding	9/2658	28/18639	0.321428571428571	2.25399064817801	0.0128616070057544	0.0538007560850878
GO:0042809	nuclear vitamin D receptor binding	6/2658	15/18639	0.4	2.80496613995485	0.013186472010732	0.0546043840981318
GO:0141050	histone H3K deacetylase activity	6/2658	15/18639	0.4	2.80496613995485	0.013186472010732	0.0546043840981318
GO:0141051	histone H4K deacetylase activity	6/2658	15/18639	0.4	2.80496613995485	0.013186472010732	0.0546043840981318
GO:0034212	protein N-acetyltransferase activity	14/2658	53/18639	0.264150943396226	1.85233613015887	0.0143906209919528	0.0593913923213034
GO:0035064	methylated histone binding	18/2658	74/18639	0.243243243243243	1.70572265267525	0.0144774382507603	0.0595505293381275
GO:0043998	histone H2A acetyltransferase activity	8/2658	24/18639	0.333333333333333	2.33747178329571	0.0148347245467819	0.06081744216189
GO:0035091	phosphatidylinositol binding	54/2658	284/18639	0.190140845070423	1.33334658061234	0.0155433123823136	0.0635114154959437
GO:0016779	nucleotidyltransferase activity	29/2658	136/18639	0.213235294117647	1.49529444960829	0.0159080058825318	0.0647870602608719
GO:0106222	lncRNA binding	9/2658	29/18639	0.310344827586207	2.17626683272359	0.0163427732110513	0.066338757047491
GO:0031593	polyubiquitin modification-dependent protein binding	15/2658	59/18639	0.254237288135593	1.78281746183571	0.0164210301161262	0.0664378726665565
GO:0042288	MHC class I protein binding	7/2658	20/18639	0.35	2.4543453724605	0.016841923631419	0.0676968526422511
GO:0043024	ribosomal small subunit binding	7/2658	20/18639	0.35	2.4543453724605	0.016841923631419	0.0676968526422511
GO:0005525	GTP binding	69/2658	378/18639	0.182539682539683	1.28004407180479	0.0172747437631946	0.0692111487135783
GO:0060590	ATPase regulator activity	13/2658	49/18639	0.26530612244898	1.86043672548026	0.0173494854880694	0.0692856475478239
GO:0005095	GTPase inhibitor activity	5/2658	12/18639	0.416666666666667	2.92183972911964	0.0194496536809163	0.0759521286147175
GO:0016273	arginine N-methyltransferase activity	5/2658	12/18639	0.416666666666667	2.92183972911964	0.0194496536809163	0.0759521286147175
GO:0016274	protein-arginine N-methyltransferase activity	5/2658	12/18639	0.416666666666667	2.92183972911964	0.0194496536809163	0.0759521286147175
GO:0035497	cAMP response element binding	5/2658	12/18639	0.416666666666667	2.92183972911964	0.0194496536809163	0.0759521286147175
GO:0070410	co-SMAD binding	5/2658	12/18639	0.416666666666667	2.92183972911964	0.0194496536809163	0.0759521286147175
GO:0141221	histone deacetylase activity, hydrolytic mechanism	5/2658	12/18639	0.416666666666667	2.92183972911964	0.0194496536809163	0.0759521286147175
GO:1990247	N6-methyladenosine-containing RNA reader activity	5/2658	12/18639	0.416666666666667	2.92183972911964	0.0194496536809163	0.0759521286147175
GO:0003924	GTPase activity	61/2658	331/18639	0.18429003021148	1.29231823668615	0.0199829833910316	0.0777886482792837
GO:0001965	G-protein alpha-subunit binding	9/2658	30/18639	0.3	2.10372460496614	0.0204658097768494	0.0791686810803517
GO:0031624	ubiquitin conjugating enzyme binding	9/2658	30/18639	0.3	2.10372460496614	0.0204658097768494	0.0791686810803517
GO:0061631	ubiquitin conjugating enzyme activity	10/2658	35/18639	0.285714285714286	2.0035472428249	0.02107328776741	0.0812638659530747
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	11/2658	40/18639	0.275	1.92841422121896	0.0211829943071426	0.0814324454050279
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	7/2658	21/18639	0.333333333333333	2.33747178329571	0.022222593003792	0.0848999373581402
GO:0072542	protein phosphatase activator activity	7/2658	21/18639	0.333333333333333	2.33747178329571	0.022222593003792	0.0848999373581402
GO:0005048	signal sequence binding	13/2658	51/18639	0.254901960784314	1.78747842252025	0.0239905826888019	0.0913715402406836
GO:0005160	transforming growth factor beta receptor binding	8/2658	26/18639	0.307692307692308	2.15766626150373	0.0242914089075904	0.0922326110522048
GO:0043022	ribosome binding	24/2658	112/18639	0.214285714285714	1.50266043211867	0.0250520348495118	0.0948288681113424
GO:0051787	misfolded protein binding	6/2658	17/18639	0.352941176470588	2.47497012348958	0.0253473990941221	0.0956534877129866
GO:0044390	ubiquitin-like protein conjugating enzyme binding	10/2658	36/18639	0.277777777777778	1.94789315274643	0.0255543350933542	0.096140394832924
GO:0005516	calmodulin binding	40/2658	207/18639	0.193236714975845	1.35505610625838	0.0264385892439371	0.0991647997781714
GO:0016504	peptidase activator activity	14/2658	57/18639	0.245614035087719	1.72234762979684	0.0266949330343912	0.0998228708013294
GO:0004535	poly(A)-specific ribonuclease activity	5/2658	13/18639	0.384615384615385	2.69708282687967	0.0279637731708441	0.103625513792257
GO:0097157	pre-mRNA intronic binding	5/2658	13/18639	0.384615384615385	2.69708282687967	0.0279637731708441	0.103625513792257
GO:0140666	annealing activity	5/2658	13/18639	0.384615384615385	2.69708282687967	0.0279637731708441	0.103625513792257
GO:0019001	guanyl nucleotide binding	71/2658	400/18639	0.1775	1.24470372460497	0.0284196892524954	0.104686258321132
GO:0032561	guanyl ribonucleotide binding	71/2658	400/18639	0.1775	1.24470372460497	0.0284196892524954	0.104686258321132
GO:0031492	nucleosomal DNA binding	11/2658	42/18639	0.261904761904762	1.83658497258949	0.0300275341777175	0.109952454526123
GO:0048487	beta-tubulin binding	11/2658	42/18639	0.261904761904762	1.83658497258949	0.0300275341777175	0.109952454526123
GO:0008408	3'-5' exonuclease activity	14/2658	58/18639	0.241379310344828	1.69265198100724	0.0307186354994776	0.112150284634187
GO:0051018	protein kinase A binding	13/2658	53/18639	0.245283018867925	1.72002640657609	0.032343426898577	0.117733890244378
GO:0008168	methyltransferase activity	39/2658	204/18639	0.191176470588235	1.34060881689019	0.0327077756845067	0.11870998586671
GO:0051082	unfolded protein binding	25/2658	121/18639	0.206611570247934	1.4488461466709	0.033989659033877	0.123000701606464
GO:0003887	DNA-directed DNA polymerase activity	7/2658	23/18639	0.304347826086957	2.13421336735695	0.0363009711691221	0.130219181461328
GO:0005158	insulin receptor binding	7/2658	23/18639	0.304347826086957	2.13421336735695	0.0363009711691221	0.130219181461328
GO:0043274	phospholipase binding	7/2658	23/18639	0.304347826086957	2.13421336735695	0.0363009711691221	0.130219181461328
GO:0042162	telomeric DNA binding	10/2658	38/18639	0.263157894736842	1.84537246049661	0.0364860594486076	0.130503760462556
GO:0017069	snRNA binding	13/2658	54/18639	0.240740740740741	1.68817406571357	0.0372256931551713	0.132417402962838
GO:0140311	protein sequestering activity	9/2658	33/18639	0.272727272727273	1.91247691360558	0.0372356878671839	0.132417402962838
GO:0070742	C2H2 zinc finger domain binding	5/2658	14/18639	0.357142857142857	2.50443405353112	0.0385102517966837	0.136556467577896
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	14/2658	60/18639	0.233333333333333	1.636230248307	0.0400601332218736	0.141645284801696
GO:0001094	TFIID-class transcription factor complex binding	4/2658	10/18639	0.4	2.80496613995485	0.0423938689117014	0.144513906732153
GO:0004862	cAMP-dependent protein kinase inhibitor activity	4/2658	10/18639	0.4	2.80496613995485	0.0423938689117014	0.144513906732153
GO:0005031	tumor necrosis factor receptor activity	4/2658	10/18639	0.4	2.80496613995485	0.0423938689117014	0.144513906732153
GO:0005522	profilin binding	4/2658	10/18639	0.4	2.80496613995485	0.0423938689117014	0.144513906732153
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	4/2658	10/18639	0.4	2.80496613995485	0.0423938689117014	0.144513906732153
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	4/2658	10/18639	0.4	2.80496613995485	0.0423938689117014	0.144513906732153
GO:0043422	protein kinase B binding	4/2658	10/18639	0.4	2.80496613995485	0.0423938689117014	0.144513906732153
GO:0070513	death domain binding	4/2658	10/18639	0.4	2.80496613995485	0.0423938689117014	0.144513906732153
GO:0098505	G-rich strand telomeric DNA binding	4/2658	10/18639	0.4	2.80496613995485	0.0423938689117014	0.144513906732153
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	4/2658	10/18639	0.4	2.80496613995485	0.0423938689117014	0.144513906732153
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	4/2658	10/18639	0.4	2.80496613995485	0.0423938689117014	0.144513906732153
GO:1905394	retromer complex binding	4/2658	10/18639	0.4	2.80496613995485	0.0423938689117014	0.144513906732153
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	4/2658	10/18639	0.4	2.80496613995485	0.0423938689117014	0.144513906732153
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	9/2658	34/18639	0.264705882352941	1.85622759261718	0.044451387489661	0.151110226342264
GO:0016741	transferase activity, transferring one-carbon groups	40/2658	215/18639	0.186046511627907	1.30463541393249	0.0450678331453018	0.152723956512533
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	8/2658	29/18639	0.275862068965517	1.93445940686542	0.0452973809429394	0.152723956512533
GO:0097472	cyclin-dependent protein kinase activity	8/2658	29/18639	0.275862068965517	1.93445940686542	0.0452973809429394	0.152723956512533
GO:0016407	acetyltransferase activity	20/2658	96/18639	0.208333333333333	1.46091986455982	0.0497181000311365	0.167172031167364
GO:0004177	aminopeptidase activity	10/2658	40/18639	0.25	1.75310383747178	0.0502890222326731	0.16772068495978
GO:0061791	GTPase motor activity	10/2658	40/18639	0.25	1.75310383747178	0.0502890222326731	0.16772068495978
GO:1990606	membrane scission GTPase motor activity	10/2658	40/18639	0.25	1.75310383747178	0.0502890222326731	0.16772068495978
GO:0004559	alpha-mannosidase activity	5/2658	15/18639	0.333333333333333	2.33747178329571	0.0511721416896594	0.170205991496064
GO:0030544	Hsp70 protein binding	12/2658	51/18639	0.235294117647059	1.64998008232638	0.051734372407556	0.171613482663774
GO:0043015	gamma-tubulin binding	9/2658	35/18639	0.257142857142857	1.80319251854241	0.0525438066242863	0.173831253014395
GO:0000287	magnesium ion binding	42/2658	230/18639	0.182608695652174	1.28052802041417	0.0528339352042417	0.174323732732712
GO:0051721	protein phosphatase 2A binding	8/2658	30/18639	0.266666666666667	1.86997742663657	0.0543270431851539	0.178772190107946
GO:0016505	peptidase activator activity involved in apoptotic process	6/2658	20/18639	0.3	2.10372460496614	0.0546181992891161	0.178776811466231
GO:0061608	nuclear import signal receptor activity	6/2658	20/18639	0.3	2.10372460496614	0.0546181992891161	0.178776811466231
GO:0030291	protein serine/threonine kinase inhibitor activity	11/2658	46/18639	0.239130434782609	1.67688193149475	0.0550330118970792	0.178936551542907
GO:0015662	P-type ion transporter activity	7/2658	25/18639	0.28	1.9634762979684	0.0552470228021456	0.178936551542907
GO:0019211	phosphatase activator activity	7/2658	25/18639	0.28	1.9634762979684	0.0552470228021456	0.178936551542907
GO:0140358	P-type transmembrane transporter activity	7/2658	25/18639	0.28	1.9634762979684	0.0552470228021456	0.178936551542907
GO:0004540	RNA nuclease activity	24/2658	121/18639	0.198347107438017	1.39089230080406	0.0562539735059107	0.181720951063596
GO:0000049	tRNA binding	17/2658	80/18639	0.2125	1.49013826185102	0.0568635394234612	0.183210463834337
GO:0061650	ubiquitin-like protein conjugating enzyme activity	10/2658	41/18639	0.24390243902439	1.71034520728954	0.0583413152182506	0.187110400747915
GO:0005080	protein kinase C binding	12/2658	52/18639	0.230769230769231	1.6182496961278	0.0588727115892278	0.187110400747915
GO:0015173	aromatic amino acid transmembrane transporter activity	4/2658	11/18639	0.363636363636364	2.54996921814078	0.0592870070441124	0.187110400747915
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	4/2658	11/18639	0.363636363636364	2.54996921814078	0.0592870070441124	0.187110400747915
GO:0034713	type I transforming growth factor beta receptor binding	4/2658	11/18639	0.363636363636364	2.54996921814078	0.0592870070441124	0.187110400747915
GO:0042608	T cell receptor binding	4/2658	11/18639	0.363636363636364	2.54996921814078	0.0592870070441124	0.187110400747915
GO:0140031	phosphorylation-dependent protein binding	4/2658	11/18639	0.363636363636364	2.54996921814078	0.0592870070441124	0.187110400747915
GO:0180030	inositol phosphate kinase activity	4/2658	11/18639	0.363636363636364	2.54996921814078	0.0592870070441124	0.187110400747915
GO:0008017	microtubule binding	49/2658	276/18639	0.177536231884058	1.24495779762489	0.0595325908627398	0.187406166134237
GO:0008080	N-acetyltransferase activity	15/2658	69/18639	0.217391304347826	1.52443811954068	0.0597276973479301	0.187541930095027
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	24/2658	122/18639	0.19672131147541	1.37949154424009	0.0609308972854055	0.190834333122311
GO:0003688	DNA replication origin binding	5/2658	16/18639	0.3125	2.19137979683973	0.0659787726849089	0.203544513732944
GO:0015923	mannosidase activity	5/2658	16/18639	0.3125	2.19137979683973	0.0659787726849089	0.203544513732944
GO:0031435	mitogen-activated protein kinase kinase kinase binding	5/2658	16/18639	0.3125	2.19137979683973	0.0659787726849089	0.203544513732944
GO:0034450	ubiquitin-ubiquitin ligase activity	5/2658	16/18639	0.3125	2.19137979683973	0.0659787726849089	0.203544513732944
GO:0043023	ribosomal large subunit binding	5/2658	16/18639	0.3125	2.19137979683973	0.0659787726849089	0.203544513732944
GO:0140328	floppase activity	5/2658	16/18639	0.3125	2.19137979683973	0.0659787726849089	0.203544513732944
GO:0016251	RNA polymerase II general transcription initiation factor activity	12/2658	53/18639	0.226415094339623	1.58771668299331	0.0666373802791742	0.204597576517449
GO:0070006	metalloaminopeptidase activity	7/2658	26/18639	0.269230769230769	1.88795797881577	0.0666517226580343	0.204597576517449
GO:0051879	Hsp90 protein binding	10/2658	42/18639	0.238095238095238	1.66962270235408	0.0671893717934171	0.20573619055354
GO:0044325	transmembrane transporter binding	26/2658	136/18639	0.191176470588235	1.34060881689019	0.0704419986256318	0.215161946297103
GO:0000149	SNARE binding	21/2658	106/18639	0.19811320754717	1.38925209761915	0.0712713045917679	0.216622635138526
GO:0008013	beta-catenin binding	21/2658	106/18639	0.19811320754717	1.38925209761915	0.0712713045917679	0.216622635138526
GO:0019213	deacetylase activity	9/2658	37/18639	0.243243243243243	1.70572265267525	0.0714601263972619	0.216662889371551
GO:0015485	cholesterol binding	12/2658	54/18639	0.222222222222222	1.55831452219714	0.0750407194574609	0.226961391692418
GO:0140142	nucleocytoplasmic carrier activity	8/2658	32/18639	0.25	1.75310383747178	0.0756162788265347	0.228143002620889
GO:0030165	PDZ domain binding	17/2658	83/18639	0.204819277108434	1.43627784274797	0.0758840851048609	0.228392587852191
GO:0008375	acetylglucosaminyltransferase activity	10/2658	43/18639	0.232558139534884	1.63079426741561	0.0768470739665078	0.23072819774859
GO:0004000	adenosine deaminase activity	4/2658	12/18639	0.333333333333333	2.33747178329571	0.0792056837257104	0.232713842184587
GO:0008603	cAMP-dependent protein kinase regulator activity	4/2658	12/18639	0.333333333333333	2.33747178329571	0.0792056837257104	0.232713842184587
GO:0043047	single-stranded telomeric DNA binding	4/2658	12/18639	0.333333333333333	2.33747178329571	0.0792056837257104	0.232713842184587
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	4/2658	12/18639	0.333333333333333	2.33747178329571	0.0792056837257104	0.232713842184587
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	4/2658	12/18639	0.333333333333333	2.33747178329571	0.0792056837257104	0.232713842184587
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	4/2658	12/18639	0.333333333333333	2.33747178329571	0.0792056837257104	0.232713842184587
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	4/2658	12/18639	0.333333333333333	2.33747178329571	0.0792056837257104	0.232713842184587
GO:1990459	transferrin receptor binding	4/2658	12/18639	0.333333333333333	2.33747178329571	0.0792056837257104	0.232713842184587
GO:1990817	poly(A) RNA polymerase activity	4/2658	12/18639	0.333333333333333	2.33747178329571	0.0792056837257104	0.232713842184587
GO:0061133	endopeptidase activator activity	6/2658	22/18639	0.272727272727273	1.91247691360558	0.0821615116939174	0.240824953516138
GO:0036041	long-chain fatty acid binding	5/2658	17/18639	0.294117647058824	2.06247510290798	0.0829085116810699	0.241865492705533
GO:0046965	nuclear retinoid X receptor binding	5/2658	17/18639	0.294117647058824	2.06247510290798	0.0829085116810699	0.241865492705533
GO:0015026	coreceptor activity	13/2658	61/18639	0.213114754098361	1.49444917292677	0.0864362564782649	0.251562123807026
GO:0051959	dynein light intermediate chain binding	7/2658	28/18639	0.25	1.75310383747178	0.0933849512184041	0.271145952478849
GO:0030145	manganese ion binding	14/2658	68/18639	0.205882352941176	1.44373257203559	0.0971381087481519	0.280066416343971
GO:0032934	sterol binding	14/2658	68/18639	0.205882352941176	1.44373257203559	0.0971381087481519	0.280066416343971
GO:0140223	general transcription initiation factor activity	14/2658	68/18639	0.205882352941176	1.44373257203559	0.0971381087481519	0.280066416343971
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	6/2658	23/18639	0.260869565217391	1.82932574344882	0.0983475848203157	0.282234696902953
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	6/2658	23/18639	0.260869565217391	1.82932574344882	0.0983475848203157	0.282234696902953
GO:1901981	phosphatidylinositol phosphate binding	33/2658	185/18639	0.178378378378378	1.25086327862852	0.100463659643167	0.287313139004709
GO:0030332	cyclin binding	8/2658	34/18639	0.235294117647059	1.64998008232638	0.10126627730087	0.287313139004709
GO:0008525	phosphatidylcholine transporter activity	5/2658	18/18639	0.277777777777778	1.94789315274643	0.101893364314039	0.287313139004709
GO:1990381	ubiquitin-specific protease binding	5/2658	18/18639	0.277777777777778	1.94789315274643	0.101893364314039	0.287313139004709
GO:0005035	death receptor activity	4/2658	13/18639	0.307692307692308	2.15766626150373	0.10197986619454	0.287313139004709
GO:0043560	insulin receptor substrate binding	4/2658	13/18639	0.307692307692308	2.15766626150373	0.10197986619454	0.287313139004709
GO:0046974	histone H3K9 methyltransferase activity	4/2658	13/18639	0.307692307692308	2.15766626150373	0.10197986619454	0.287313139004709
GO:0140333	glycerophospholipid flippase activity	4/2658	13/18639	0.307692307692308	2.15766626150373	0.10197986619454	0.287313139004709
GO:0019003	GDP binding	15/2658	75/18639	0.2	1.40248306997743	0.107168398973786	0.301243290053877
GO:0030276	clathrin binding	10/2658	46/18639	0.217391304347826	1.52443811954068	0.110721350048099	0.310523058998531
GO:0016410	N-acyltransferase activity	18/2658	94/18639	0.191489361702128	1.34280293934009	0.115321865006541	0.322628304448539
GO:0034061	DNA polymerase activity	8/2658	35/18639	0.228571428571429	1.60283779425992	0.115702564908747	0.322628304448539
GO:0030552	cAMP binding	6/2658	24/18639	0.25	1.75310383747178	0.116083441795098	0.322628304448539
GO:0070840	dynein complex binding	6/2658	24/18639	0.25	1.75310383747178	0.116083441795098	0.322628304448539
GO:0043495	protein-membrane adaptor activity	10/2658	47/18639	0.212765957446809	1.49200326593343	0.123628714950292	0.342826593817215
GO:0160215	deacylase activity	13/2658	65/18639	0.2	1.40248306997743	0.127307817490314	0.347725125112487
GO:0005161	platelet-derived growth factor receptor binding	4/2658	14/18639	0.285714285714286	2.0035472428249	0.127367711953683	0.347725125112487
GO:0008474	palmitoyl-(protein) hydrolase activity	4/2658	14/18639	0.285714285714286	2.0035472428249	0.127367711953683	0.347725125112487
GO:0042043	neurexin family protein binding	4/2658	14/18639	0.285714285714286	2.0035472428249	0.127367711953683	0.347725125112487
GO:0071933	Arp2/3 complex binding	4/2658	14/18639	0.285714285714286	2.0035472428249	0.127367711953683	0.347725125112487
GO:0098599	palmitoyl hydrolase activity	4/2658	14/18639	0.285714285714286	2.0035472428249	0.127367711953683	0.347725125112487
GO:0098847	sequence-specific single stranded DNA binding	4/2658	14/18639	0.285714285714286	2.0035472428249	0.127367711953683	0.347725125112487
GO:0004527	exonuclease activity	16/2658	84/18639	0.19047619047619	1.33569816188326	0.136449921019279	0.371698018847218
GO:0070273	phosphatidylinositol-4-phosphate binding	7/2658	31/18639	0.225806451612903	1.58344862739387	0.142963285237383	0.388583026394121
GO:0000339	RNA cap binding	5/2658	20/18639	0.25	1.75310383747178	0.145560346809123	0.393906727987846
GO:0140939	histone H4 methyltransferase activity	5/2658	20/18639	0.25	1.75310383747178	0.145560346809123	0.393906727987846
GO:0046982	protein heterodimerization activity	60/2658	369/18639	0.16260162601626	1.14023013819303	0.150627718902513	0.406727801150331
GO:0019905	syntaxin binding	12/2658	61/18639	0.19672131147541	1.37949154424009	0.151965094617928	0.409443071525159
GO:0050700	CARD domain binding	4/2658	15/18639	0.266666666666667	1.86997742663657	0.155075192049691	0.416006058672432
GO:0120283	protein serine/threonine kinase binding	4/2658	15/18639	0.266666666666667	1.86997742663657	0.155075192049691	0.416006058672432
GO:0002020	protease binding	24/2658	136/18639	0.176470588235294	1.23748506174479	0.155948078867508	0.417440193758146
GO:0005131	growth hormone receptor binding	3/2658	10/18639	0.3	2.10372460496614	0.160925797449812	0.423416703737886
GO:0008239	dipeptidyl-peptidase activity	3/2658	10/18639	0.3	2.10372460496614	0.160925797449812	0.423416703737886
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/2658	10/18639	0.3	2.10372460496614	0.160925797449812	0.423416703737886
GO:0031434	mitogen-activated protein kinase kinase binding	3/2658	10/18639	0.3	2.10372460496614	0.160925797449812	0.423416703737886
GO:0031996	thioesterase binding	3/2658	10/18639	0.3	2.10372460496614	0.160925797449812	0.423416703737886
GO:0050815	phosphoserine residue binding	3/2658	10/18639	0.3	2.10372460496614	0.160925797449812	0.423416703737886
GO:0070097	delta-catenin binding	3/2658	10/18639	0.3	2.10372460496614	0.160925797449812	0.423416703737886
GO:1990757	ubiquitin ligase activator activity	3/2658	10/18639	0.3	2.10372460496614	0.160925797449812	0.423416703737886
GO:0031369	translation initiation factor binding	7/2658	32/18639	0.21875	1.53396585778781	0.161820447032421	0.424864748165973
GO:0003684	damaged DNA binding	14/2658	74/18639	0.189189189189189	1.32667317430297	0.162241408035064	0.425065599820103
GO:0005548	phospholipid transporter activity	13/2658	68/18639	0.191176470588235	1.34060881689019	0.163998273735876	0.428758198707778
GO:0019205	nucleobase-containing compound kinase activity	9/2658	44/18639	0.204545454545455	1.43435768520419	0.166596147748789	0.434629273408046
GO:0070182	DNA polymerase binding	5/2658	21/18639	0.238095238095238	1.66962270235408	0.16993031712346	0.442392428966982
GO:0004683	calcium/calmodulin-dependent protein kinase activity	6/2658	27/18639	0.222222222222222	1.55831452219714	0.177751256874199	0.459842874177698
GO:0023026	MHC class II protein complex binding	6/2658	27/18639	0.222222222222222	1.55831452219714	0.177751256874199	0.459842874177698
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	6/2658	27/18639	0.222222222222222	1.55831452219714	0.177751256874199	0.459842874177698
GO:0019239	deaminase activity	7/2658	33/18639	0.212121212121212	1.48748204391545	0.181722626020585	0.469133306505024
GO:0004707	MAP kinase activity	4/2658	16/18639	0.25	1.75310383747178	0.184773998504618	0.471097343294833
GO:0022858	alanine transmembrane transporter activity	4/2658	16/18639	0.25	1.75310383747178	0.184773998504618	0.471097343294833
GO:0030275	LRR domain binding	4/2658	16/18639	0.25	1.75310383747178	0.184773998504618	0.471097343294833
GO:0070411	I-SMAD binding	4/2658	16/18639	0.25	1.75310383747178	0.184773998504618	0.471097343294833
GO:0097027	ubiquitin-protein transferase activator activity	4/2658	16/18639	0.25	1.75310383747178	0.184773998504618	0.471097343294833
GO:0140327	flippase activity	4/2658	16/18639	0.25	1.75310383747178	0.184773998504618	0.471097343294833
GO:0031683	G-protein beta/gamma-subunit complex binding	5/2658	22/18639	0.227272727272727	1.59373076133798	0.195744671661561	0.495193113534891
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/2658	11/18639	0.272727272727273	1.91247691360558	0.19904034385195	0.495193113534891
GO:0002162	dystroglycan binding	3/2658	11/18639	0.272727272727273	1.91247691360558	0.19904034385195	0.495193113534891
GO:0005114	type II transforming growth factor beta receptor binding	3/2658	11/18639	0.272727272727273	1.91247691360558	0.19904034385195	0.495193113534891
GO:0005225	volume-sensitive anion channel activity	3/2658	11/18639	0.272727272727273	1.91247691360558	0.19904034385195	0.495193113534891
GO:0008526	phosphatidylinositol transfer activity	3/2658	11/18639	0.272727272727273	1.91247691360558	0.19904034385195	0.495193113534891
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	3/2658	11/18639	0.272727272727273	1.91247691360558	0.19904034385195	0.495193113534891
GO:0019864	IgG binding	3/2658	11/18639	0.272727272727273	1.91247691360558	0.19904034385195	0.495193113534891
GO:0032794	GTPase activating protein binding	3/2658	11/18639	0.272727272727273	1.91247691360558	0.19904034385195	0.495193113534891
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/2658	11/18639	0.272727272727273	1.91247691360558	0.19904034385195	0.495193113534891
GO:0043522	leucine zipper domain binding	3/2658	11/18639	0.272727272727273	1.91247691360558	0.19904034385195	0.495193113534891
GO:0045294	alpha-catenin binding	3/2658	11/18639	0.272727272727273	1.91247691360558	0.19904034385195	0.495193113534891
GO:0004896	cytokine receptor activity	17/2658	96/18639	0.177083333333333	1.24178188487585	0.202114849440823	0.501830431005986
GO:0120013	lipid transfer activity	12/2658	65/18639	0.184615384615385	1.29459975690224	0.209248712377264	0.518499821432819
GO:0051117	ATPase binding	15/2658	84/18639	0.178571428571429	1.25221702676556	0.210989889807689	0.521766581207792
GO:0070888	E-box binding	11/2658	59/18639	0.186440677966102	1.30739947201286	0.212966121245909	0.524977669135693
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	4/2658	17/18639	0.235294117647059	1.64998008232638	0.216117225219556	0.524977669135693
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	4/2658	17/18639	0.235294117647059	1.64998008232638	0.216117225219556	0.524977669135693
GO:0005092	GDP-dissociation inhibitor activity	4/2658	17/18639	0.235294117647059	1.64998008232638	0.216117225219556	0.524977669135693
GO:0008429	phosphatidylethanolamine binding	4/2658	17/18639	0.235294117647059	1.64998008232638	0.216117225219556	0.524977669135693
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	4/2658	17/18639	0.235294117647059	1.64998008232638	0.216117225219556	0.524977669135693
GO:0019198	transmembrane receptor protein phosphatase activity	4/2658	17/18639	0.235294117647059	1.64998008232638	0.216117225219556	0.524977669135693
GO:0030169	low-density lipoprotein particle binding	4/2658	17/18639	0.235294117647059	1.64998008232638	0.216117225219556	0.524977669135693
GO:0048038	quinone binding	4/2658	17/18639	0.235294117647059	1.64998008232638	0.216117225219556	0.524977669135693
GO:0042169	SH2 domain binding	8/2658	41/18639	0.195121951219512	1.36827616583164	0.222425763510301	0.539087219254582
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	5/2658	23/18639	0.217391304347826	1.52443811954068	0.222799418006351	0.539087219254582
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	22/2658	130/18639	0.169230769230769	1.18671644382705	0.224005782309996	0.540945470392436
GO:0008235	metalloexopeptidase activity	12/2658	66/18639	0.181818181818182	1.27498460907039	0.224863784506278	0.54195685562646
GO:0051015	actin filament binding	34/2658	209/18639	0.162679425837321	1.14077570285245	0.227850932624658	0.548085869120523
GO:0003779	actin binding	69/2658	443/18639	0.155756207674944	1.09222722153998	0.229732660207611	0.551537164778583
GO:0043178	alcohol binding	16/2658	92/18639	0.173913043478261	1.21955049563254	0.232977147193794	0.558240387644935
GO:0000340	RNA 7-methylguanosine cap binding	3/2658	12/18639	0.25	1.75310383747178	0.238985230560696	0.562801096396754
GO:0003995	acyl-CoA dehydrogenase activity	3/2658	12/18639	0.25	1.75310383747178	0.238985230560696	0.562801096396754
GO:0005078	MAP-kinase scaffold activity	3/2658	12/18639	0.25	1.75310383747178	0.238985230560696	0.562801096396754
GO:0015166	polyol transmembrane transporter activity	3/2658	12/18639	0.25	1.75310383747178	0.238985230560696	0.562801096396754
GO:0035197	siRNA binding	3/2658	12/18639	0.25	1.75310383747178	0.238985230560696	0.562801096396754
GO:0045295	gamma-catenin binding	3/2658	12/18639	0.25	1.75310383747178	0.238985230560696	0.562801096396754
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	3/2658	12/18639	0.25	1.75310383747178	0.238985230560696	0.562801096396754
GO:0070008	serine-type exopeptidase activity	3/2658	12/18639	0.25	1.75310383747178	0.238985230560696	0.562801096396754
GO:0097677	STAT family protein binding	3/2658	12/18639	0.25	1.75310383747178	0.238985230560696	0.562801096396754
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	12/2658	67/18639	0.17910447761194	1.25595498803949	0.240932352026795	0.566305756954409
GO:0016859	cis-trans isomerase activity	8/2658	42/18639	0.19047619047619	1.33569816188326	0.242998846746599	0.570077142367498
GO:0005484	SNAP receptor activity	7/2658	36/18639	0.194444444444444	1.3635252069225	0.246779655123037	0.576753966708007
GO:0055106	ubiquitin-protein transferase regulator activity	7/2658	36/18639	0.194444444444444	1.3635252069225	0.246779655123037	0.576753966708007
GO:0003746	translation elongation factor activity	4/2658	18/18639	0.222222222222222	1.55831452219714	0.248752614049704	0.57699384537093
GO:0017075	syntaxin-1 binding	4/2658	18/18639	0.222222222222222	1.55831452219714	0.248752614049704	0.57699384537093
GO:0031690	adrenergic receptor binding	4/2658	18/18639	0.222222222222222	1.55831452219714	0.248752614049704	0.57699384537093
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	4/2658	18/18639	0.222222222222222	1.55831452219714	0.248752614049704	0.57699384537093
GO:0070566	adenylyltransferase activity	6/2658	30/18639	0.2	1.40248306997743	0.249667314661938	0.577591587568767
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	5/2658	24/18639	0.208333333333333	1.46091986455982	0.250882569640891	0.577591587568767
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	5/2658	24/18639	0.208333333333333	1.46091986455982	0.250882569640891	0.577591587568767
GO:0070300	phosphatidic acid binding	5/2658	24/18639	0.208333333333333	1.46091986455982	0.250882569640891	0.577591587568767
GO:0070851	growth factor receptor binding	23/2658	139/18639	0.165467625899281	1.1603277197655	0.251930163205682	0.578923317310636
GO:0016763	pentosyltransferase activity	9/2658	49/18639	0.183673469387755	1.28799465610172	0.258297329605484	0.592451495786557
GO:0030551	cyclic nucleotide binding	7/2658	37/18639	0.189189189189189	1.32667317430297	0.269909614825991	0.617937782365999
GO:0008327	methyl-CpG binding	6/2658	31/18639	0.193548387096774	1.35724168062332	0.275276281723831	0.629057280828163
GO:0120020	cholesterol transfer activity	5/2658	25/18639	0.2	1.40248306997743	0.279779476418685	0.634178275963762
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/2658	13/18639	0.230769230769231	1.6182496961278	0.280086839870543	0.634178275963762
GO:0051011	microtubule minus-end binding	3/2658	13/18639	0.230769230769231	1.6182496961278	0.280086839870543	0.634178275963762
GO:0140410	monoatomic cation:bicarbonate symporter activity	3/2658	13/18639	0.230769230769231	1.6182496961278	0.280086839870543	0.634178275963762
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	3/2658	13/18639	0.230769230769231	1.6182496961278	0.280086839870543	0.634178275963762
GO:0008238	exopeptidase activity	17/2658	102/18639	0.166666666666667	1.16873589164786	0.28166710015778	0.636588281308974
GO:0016790	thiolester hydrolase activity	8/2658	44/18639	0.181818181818182	1.27498460907039	0.285851422950639	0.644864087607109
GO:0004518	nuclease activity	33/2658	209/18639	0.157894736842105	1.10722347629797	0.290252263342271	0.653597249934967
GO:0140375	immune receptor activity	25/2658	156/18639	0.16025641025641	1.12378451119986	0.295379428366562	0.663931174142691
GO:0043425	bHLH transcription factor binding	6/2658	32/18639	0.1875	1.31482787810384	0.301458397421849	0.676363022579203
GO:0051539	4 iron, 4 sulfur cluster binding	8/2658	45/18639	0.177777777777778	1.24665161775771	0.30796170093113	0.686417979275973
GO:0004112	cyclic-nucleotide phosphodiesterase activity	5/2658	26/18639	0.192307692307692	1.34854141343983	0.309277468782367	0.686417979275973
GO:0005112	Notch binding	5/2658	26/18639	0.192307692307692	1.34854141343983	0.309277468782367	0.686417979275973
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/2658	26/18639	0.192307692307692	1.34854141343983	0.309277468782367	0.686417979275973
GO:0034237	protein kinase A regulatory subunit binding	5/2658	26/18639	0.192307692307692	1.34854141343983	0.309277468782367	0.686417979275973
GO:0120014	phospholipid transfer activity	5/2658	26/18639	0.192307692307692	1.34854141343983	0.309277468782367	0.686417979275973
GO:0005543	phospholipid binding	75/2658	497/18639	0.150905432595573	1.05821157191456	0.314632154902871	0.697048616068479
GO:0015095	magnesium ion transmembrane transporter activity	4/2658	20/18639	0.2	1.40248306997743	0.31652661556671	0.699988967041793
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	7/2658	39/18639	0.179487179487179	1.25863865254384	0.317686733604091	0.700045409406159
GO:0016776	phosphotransferase activity, phosphate group as acceptor	7/2658	39/18639	0.179487179487179	1.25863865254384	0.317686733604091	0.700045409406159
GO:0004705	JUN kinase activity	3/2658	14/18639	0.214285714285714	1.50266043211867	0.321737511120596	0.702697502164275
GO:0015926	glucosidase activity	3/2658	14/18639	0.214285714285714	1.50266043211867	0.321737511120596	0.702697502164275
GO:0019763	immunoglobulin receptor activity	3/2658	14/18639	0.214285714285714	1.50266043211867	0.321737511120596	0.702697502164275
GO:0044548	S100 protein binding	3/2658	14/18639	0.214285714285714	1.50266043211867	0.321737511120596	0.702697502164275
GO:1990825	sequence-specific mRNA binding	3/2658	14/18639	0.214285714285714	1.50266043211867	0.321737511120596	0.702697502164275
GO:0050997	quaternary ammonium group binding	7/2658	40/18639	0.175	1.22717268623025	0.342113859755391	0.745880747240552
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	4/2658	21/18639	0.19047619047619	1.33569816188326	0.351019862259239	0.759927210575266
GO:0005123	death receptor binding	4/2658	21/18639	0.19047619047619	1.33569816188326	0.351019862259239	0.759927210575266
GO:0008373	sialyltransferase activity	4/2658	21/18639	0.19047619047619	1.33569816188326	0.351019862259239	0.759927210575266
GO:0140312	cargo adaptor activity	4/2658	21/18639	0.19047619047619	1.33569816188326	0.351019862259239	0.759927210575266
GO:0005178	integrin binding	25/2658	161/18639	0.15527950310559	1.08888437110049	0.354996819585928	0.767191025164684
GO:0003925	G protein activity	9/2658	54/18639	0.166666666666667	1.16873589164786	0.362040001229618	0.779894633315113
GO:0000774	adenyl-nucleotide exchange factor activity	3/2658	15/18639	0.2	1.40248306997743	0.363403090888323	0.779894633315113
GO:0004129	cytochrome-c oxidase activity	3/2658	15/18639	0.2	1.40248306997743	0.363403090888323	0.779894633315113
GO:0015929	hexosaminidase activity	3/2658	15/18639	0.2	1.40248306997743	0.363403090888323	0.779894633315113
GO:0004812	aminoacyl-tRNA ligase activity	7/2658	41/18639	0.170731707317073	1.19724164510268	0.36675552662938	0.784361039619853
GO:0016875	ligase activity, forming carbon-oxygen bonds	7/2658	41/18639	0.170731707317073	1.19724164510268	0.36675552662938	0.784361039619853
GO:0001618	virus receptor activity	13/2658	81/18639	0.160493827160494	1.12544937714238	0.368361990037365	0.786433729595342
GO:0005496	steroid binding	17/2658	108/18639	0.157407407407407	1.10380611988964	0.369733861650489	0.787999283724876
GO:0008970	phospholipase A1 activity	4/2658	22/18639	0.181818181818182	1.27498460907039	0.385525460169835	0.818188866201929
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	4/2658	22/18639	0.181818181818182	1.27498460907039	0.385525460169835	0.818188866201929
GO:0140272	exogenous protein binding	13/2658	82/18639	0.158536585365854	1.1117243847382	0.385888103832677	0.818188866201929
GO:0009055	electron transfer activity	18/2658	116/18639	0.155172413793103	1.0881334163618	0.38808805399729	0.821441953057729
GO:0015179	L-amino acid transmembrane transporter activity	10/2658	62/18639	0.161290322580645	1.13103473385276	0.389709071944414	0.823460607498984
GO:0003785	actin monomer binding	5/2658	29/18639	0.172413793103448	1.20903712929089	0.3993586289146	0.839892401269043
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	5/2658	29/18639	0.172413793103448	1.20903712929089	0.3993586289146	0.839892401269043
GO:0017022	myosin binding	12/2658	76/18639	0.157894736842105	1.10722347629797	0.399527422645809	0.839892401269043
GO:0005126	cytokine receptor binding	41/2658	275/18639	0.149090909090909	1.04548737943772	0.404363774955317	0.842002501496296
GO:0000062	fatty-acyl-CoA binding	3/2658	16/18639	0.1875	1.31482787810384	0.404625189130716	0.842002501496296
GO:0005159	insulin-like growth factor receptor binding	3/2658	16/18639	0.1875	1.31482787810384	0.404625189130716	0.842002501496296
GO:0008142	oxysterol binding	3/2658	16/18639	0.1875	1.31482787810384	0.404625189130716	0.842002501496296
GO:0015385	sodium:proton antiporter activity	3/2658	16/18639	0.1875	1.31482787810384	0.404625189130716	0.842002501496296
GO:0016675	oxidoreductase activity, acting on a heme group of donors	3/2658	16/18639	0.1875	1.31482787810384	0.404625189130716	0.842002501496296
GO:0045505	dynein intermediate chain binding	6/2658	36/18639	0.166666666666667	1.16873589164786	0.40902951950994	0.849734725715936
GO:0016782	transferase activity, transferring sulphur-containing groups	11/2658	70/18639	0.157142857142857	1.10195098355369	0.414279813617459	0.859195445384781
GO:0022853	active monoatomic ion transmembrane transporter activity	18/2658	118/18639	0.152542372881356	1.06969047710143	0.41772851069738	0.859302592591659
GO:0017134	fibroblast growth factor binding	4/2658	23/18639	0.173913043478261	1.21955049563254	0.419783574309516	0.859302592591659
GO:0042171	lysophosphatidic acid acyltransferase activity	4/2658	23/18639	0.173913043478261	1.21955049563254	0.419783574309516	0.859302592591659
GO:0071617	lysophospholipid acyltransferase activity	4/2658	23/18639	0.173913043478261	1.21955049563254	0.419783574309516	0.859302592591659
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	34/2658	229/18639	0.148471615720524	1.04114463710115	0.427827342443061	0.859302592591659
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/2658	10/18639	0.2	1.40248306997743	0.428258585448841	0.859302592591659
GO:0004090	carbonyl reductase (NADPH) activity	2/2658	10/18639	0.2	1.40248306997743	0.428258585448841	0.859302592591659
GO:0004955	prostaglandin receptor activity	2/2658	10/18639	0.2	1.40248306997743	0.428258585448841	0.859302592591659
GO:0005528	FK506 binding	2/2658	10/18639	0.2	1.40248306997743	0.428258585448841	0.859302592591659
GO:0008190	eukaryotic initiation factor 4E binding	2/2658	10/18639	0.2	1.40248306997743	0.428258585448841	0.859302592591659
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/2658	10/18639	0.2	1.40248306997743	0.428258585448841	0.859302592591659
GO:0015279	store-operated calcium channel activity	2/2658	10/18639	0.2	1.40248306997743	0.428258585448841	0.859302592591659
GO:0016427	tRNA (cytidine) methyltransferase activity	2/2658	10/18639	0.2	1.40248306997743	0.428258585448841	0.859302592591659
GO:0030957	Tat protein binding	2/2658	10/18639	0.2	1.40248306997743	0.428258585448841	0.859302592591659
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/2658	10/18639	0.2	1.40248306997743	0.428258585448841	0.859302592591659
GO:0043208	glycosphingolipid binding	2/2658	10/18639	0.2	1.40248306997743	0.428258585448841	0.859302592591659
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/2658	10/18639	0.2	1.40248306997743	0.428258585448841	0.859302592591659
GO:0051880	G-quadruplex DNA binding	2/2658	10/18639	0.2	1.40248306997743	0.428258585448841	0.859302592591659
GO:0140940	histone H2A methyltransferase activity	2/2658	10/18639	0.2	1.40248306997743	0.428258585448841	0.859302592591659
GO:1990259	histone H2AQ104 methyltransferase activity	2/2658	10/18639	0.2	1.40248306997743	0.428258585448841	0.859302592591659
GO:0031210	phosphatidylcholine binding	5/2658	30/18639	0.166666666666667	1.16873589164786	0.429296891765131	0.859987604607422
GO:0003954	NADH dehydrogenase activity	7/2658	44/18639	0.159090909090909	1.11561153293659	0.440940302259294	0.880055088120577
GO:0016248	channel inhibitor activity	7/2658	44/18639	0.159090909090909	1.11561153293659	0.440940302259294	0.880055088120577
GO:0016018	cyclosporin A binding	3/2658	17/18639	0.176470588235294	1.23748506174479	0.445019752825964	0.880055088120577
GO:0016805	dipeptidase activity	3/2658	17/18639	0.176470588235294	1.23748506174479	0.445019752825964	0.880055088120577
GO:0045125	bioactive lipid receptor activity	3/2658	17/18639	0.176470588235294	1.23748506174479	0.445019752825964	0.880055088120577
GO:0070402	NADPH binding	3/2658	17/18639	0.176470588235294	1.23748506174479	0.445019752825964	0.880055088120577
GO:0070403	NAD+ binding	3/2658	17/18639	0.176470588235294	1.23748506174479	0.445019752825964	0.880055088120577
GO:1901567	fatty acid derivative binding	3/2658	17/18639	0.176470588235294	1.23748506174479	0.445019752825964	0.880055088120577
GO:0019957	C-C chemokine binding	4/2658	24/18639	0.166666666666667	1.16873589164786	0.453563775243241	0.892659806459584
GO:0048027	mRNA 5'-UTR binding	4/2658	24/18639	0.166666666666667	1.16873589164786	0.453563775243241	0.892659806459584
GO:0050699	WW domain binding	4/2658	24/18639	0.166666666666667	1.16873589164786	0.453563775243241	0.892659806459584
GO:0016411	acylglycerol O-acyltransferase activity	5/2658	31/18639	0.161290322580645	1.13103473385276	0.458916239849997	0.900322162122252
GO:0047499	calcium-independent phospholipase A2 activity	5/2658	31/18639	0.161290322580645	1.13103473385276	0.458916239849997	0.900322162122252
GO:0140303	intramembrane lipid transporter activity	7/2658	45/18639	0.155555555555556	1.090820165538	0.465436360398692	0.91021944331535
GO:0141110	transporter inhibitor activity	7/2658	45/18639	0.155555555555556	1.090820165538	0.465436360398692	0.91021944331535
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0001851	complement component C3b binding	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0003953	NAD+ nucleosidase activity	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0004954	prostanoid receptor activity	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0008172	S-methyltransferase activity	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0019107	myristoyltransferase activity	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0019215	intermediate filament binding	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0032050	clathrin heavy chain binding	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0032404	mismatch repair complex binding	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0034056	estrogen response element binding	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0034511	U3 snoRNA binding	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0047676	arachidonate-CoA ligase activity	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0048185	activin binding	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0050998	nitric-oxide synthase binding	2/2658	11/18639	0.181818181818182	1.27498460907039	0.479195972470373	0.911171971037366
GO:0004857	enzyme inhibitor activity	60/2658	416/18639	0.144230769230769	1.01140606007987	0.483566473901344	0.911171971037366
GO:0008308	voltage-gated monoatomic anion channel activity	3/2658	18/18639	0.166666666666667	1.16873589164786	0.484273180581217	0.911171971037366
GO:0070064	proline-rich region binding	3/2658	18/18639	0.166666666666667	1.16873589164786	0.484273180581217	0.911171971037366
GO:0070628	proteasome binding	3/2658	18/18639	0.166666666666667	1.16873589164786	0.484273180581217	0.911171971037366
GO:1901611	phosphatidylglycerol binding	3/2658	18/18639	0.166666666666667	1.16873589164786	0.484273180581217	0.911171971037366
GO:0000030	mannosyltransferase activity	4/2658	25/18639	0.16	1.12198645598194	0.486665546447918	0.911171971037366
GO:0008483	transaminase activity	4/2658	25/18639	0.16	1.12198645598194	0.486665546447918	0.911171971037366
GO:0047617	fatty acyl-CoA hydrolase activity	4/2658	25/18639	0.16	1.12198645598194	0.486665546447918	0.911171971037366
GO:0022884	macromolecule transmembrane transporter activity	5/2658	32/18639	0.15625	1.09568989841986	0.488075099558913	0.911171971037366
GO:0047498	calcium-dependent phospholipase A2 activity	5/2658	32/18639	0.15625	1.09568989841986	0.488075099558913	0.911171971037366
GO:0071813	lipoprotein particle binding	5/2658	32/18639	0.15625	1.09568989841986	0.488075099558913	0.911171971037366
GO:0071814	protein-lipid complex binding	5/2658	32/18639	0.15625	1.09568989841986	0.488075099558913	0.911171971037366
GO:0120015	sterol transfer activity	5/2658	32/18639	0.15625	1.09568989841986	0.488075099558913	0.911171971037366
GO:0005246	calcium channel regulator activity	8/2658	53/18639	0.150943396226415	1.05847778866221	0.490165177037928	0.911646345667084
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	9/2658	60/18639	0.15	1.05186230248307	0.490545521493472	0.911646345667084
GO:0098531	ligand-modulated transcription factor activity	9/2658	60/18639	0.15	1.05186230248307	0.490545521493472	0.911646345667084
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	10/2658	68/18639	0.147058823529412	1.03123755145399	0.510691098431666	0.941559082817844
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	8/2658	54/18639	0.148148148148148	1.03887634813143	0.512447816308938	0.941559082817844
GO:0019956	chemokine binding	5/2658	33/18639	0.151515151515152	1.06248717422532	0.516648091154767	0.941559082817844
GO:0004435	phosphatidylinositol phospholipase C activity	4/2658	26/18639	0.153846153846154	1.07883313075187	0.518917924205291	0.941559082817844
GO:0016289	acyl-CoA hydrolase activity	4/2658	26/18639	0.153846153846154	1.07883313075187	0.518917924205291	0.941559082817844
GO:0019865	immunoglobulin binding	4/2658	26/18639	0.153846153846154	1.07883313075187	0.518917924205291	0.941559082817844
GO:0051139	metal cation:proton antiporter activity	4/2658	26/18639	0.153846153846154	1.07883313075187	0.518917924205291	0.941559082817844
GO:0008301	DNA binding, bending	3/2658	19/18639	0.157894736842105	1.10722347629797	0.522136896599846	0.941559082817844
GO:0008381	mechanosensitive monoatomic ion channel activity	3/2658	19/18639	0.157894736842105	1.10722347629797	0.522136896599846	0.941559082817844
GO:0031420	alkali metal ion binding	3/2658	19/18639	0.157894736842105	1.10722347629797	0.522136896599846	0.941559082817844
GO:0046624	sphingolipid transporter activity	3/2658	19/18639	0.157894736842105	1.10722347629797	0.522136896599846	0.941559082817844
GO:0050145	nucleoside monophosphate kinase activity	3/2658	19/18639	0.157894736842105	1.10722347629797	0.522136896599846	0.941559082817844
GO:0120227	acyl-CoA binding	3/2658	19/18639	0.157894736842105	1.10722347629797	0.522136896599846	0.941559082817844
GO:0000995	RNA polymerase III general transcription initiation factor activity	2/2658	12/18639	0.166666666666667	1.16873589164786	0.527238120852308	0.941559082817844
GO:0004126	cytidine deaminase activity	2/2658	12/18639	0.166666666666667	1.16873589164786	0.527238120852308	0.941559082817844
GO:0005049	nuclear export signal receptor activity	2/2658	12/18639	0.166666666666667	1.16873589164786	0.527238120852308	0.941559082817844
GO:0005165	neurotrophin receptor binding	2/2658	12/18639	0.166666666666667	1.16873589164786	0.527238120852308	0.941559082817844
GO:0005527	macrolide binding	2/2658	12/18639	0.166666666666667	1.16873589164786	0.527238120852308	0.941559082817844
GO:0008179	adenylate cyclase binding	2/2658	12/18639	0.166666666666667	1.16873589164786	0.527238120852308	0.941559082817844
GO:0016423	tRNA (guanine) methyltransferase activity	2/2658	12/18639	0.166666666666667	1.16873589164786	0.527238120852308	0.941559082817844
GO:0016840	carbon-nitrogen lyase activity	2/2658	12/18639	0.166666666666667	1.16873589164786	0.527238120852308	0.941559082817844
GO:0017166	vinculin binding	2/2658	12/18639	0.166666666666667	1.16873589164786	0.527238120852308	0.941559082817844
GO:0036009	protein-glutamine N-methyltransferase activity	2/2658	12/18639	0.166666666666667	1.16873589164786	0.527238120852308	0.941559082817844
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	2/2658	12/18639	0.166666666666667	1.16873589164786	0.527238120852308	0.941559082817844
GO:0070679	inositol 1,4,5 trisphosphate binding	2/2658	12/18639	0.166666666666667	1.16873589164786	0.527238120852308	0.941559082817844
GO:0097371	MDM2/MDM4 family protein binding	2/2658	12/18639	0.166666666666667	1.16873589164786	0.527238120852308	0.941559082817844
GO:0001540	amyloid-beta binding	12/2658	83/18639	0.144578313253012	1.01384318311621	0.527242565824255	0.941559082817844
GO:0008137	NADH dehydrogenase (ubiquinone) activity	6/2658	41/18639	0.146341463414634	1.02620712437373	0.540332203285486	0.962149983916724
GO:0016877	ligase activity, forming carbon-sulfur bonds	6/2658	41/18639	0.146341463414634	1.02620712437373	0.540332203285486	0.962149983916724
GO:0008175	tRNA methyltransferase activity	5/2658	34/18639	0.147058823529412	1.03123755145399	0.544526052013974	0.966827551345675
GO:0052866	phosphatidylinositol phosphate phosphatase activity	5/2658	34/18639	0.147058823529412	1.03123755145399	0.544526052013974	0.966827551345675
GO:0005385	zinc ion transmembrane transporter activity	4/2658	27/18639	0.148148148148148	1.03887634813143	0.550178469341762	0.972665087632856
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	4/2658	27/18639	0.148148148148148	1.03887634813143	0.550178469341762	0.972665087632856
GO:0035255	ionotropic glutamate receptor binding	4/2658	27/18639	0.148148148148148	1.03887634813143	0.550178469341762	0.972665087632856
GO:0019212	phosphatase inhibitor activity	8/2658	56/18639	0.142857142857143	1.00177362141245	0.555964179938928	0.97882328519855
GO:0016004	phospholipase activator activity	3/2658	20/18639	0.15	1.05186230248307	0.558421063840988	0.97882328519855
GO:0016408	C-acyltransferase activity	3/2658	20/18639	0.15	1.05186230248307	0.558421063840988	0.97882328519855
GO:0030742	GTP-dependent protein binding	3/2658	20/18639	0.15	1.05186230248307	0.558421063840988	0.97882328519855
GO:0052745	inositol phosphate phosphatase activity	3/2658	20/18639	0.15	1.05186230248307	0.558421063840988	0.97882328519855
GO:0140664	ATP-dependent DNA damage sensor activity	3/2658	20/18639	0.15	1.05186230248307	0.558421063840988	0.97882328519855
GO:0035254	glutamate receptor binding	7/2658	49/18639	0.142857142857143	1.00177362141245	0.560070254310525	0.980321551516579
GO:0042277	peptide binding	35/2658	249/18639	0.140562248995984	0.985680872474095	0.564874017867884	0.980643890645482
GO:0004623	phospholipase A2 activity	5/2658	35/18639	0.142857142857143	1.00177362141245	0.571615748108727	0.980643890645482
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/2658	13/18639	0.153846153846154	1.07883313075187	0.572174717394446	0.980643890645482
GO:0005172	vascular endothelial growth factor receptor binding	2/2658	13/18639	0.153846153846154	1.07883313075187	0.572174717394446	0.980643890645482
GO:0005338	nucleotide-sugar transmembrane transporter activity	2/2658	13/18639	0.153846153846154	1.07883313075187	0.572174717394446	0.980643890645482
GO:0008035	high-density lipoprotein particle binding	2/2658	13/18639	0.153846153846154	1.07883313075187	0.572174717394446	0.980643890645482
GO:0008253	5'-nucleotidase activity	2/2658	13/18639	0.153846153846154	1.07883313075187	0.572174717394446	0.980643890645482
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/2658	13/18639	0.153846153846154	1.07883313075187	0.572174717394446	0.980643890645482
GO:0019855	calcium channel inhibitor activity	2/2658	13/18639	0.153846153846154	1.07883313075187	0.572174717394446	0.980643890645482
GO:0030955	potassium ion binding	2/2658	13/18639	0.153846153846154	1.07883313075187	0.572174717394446	0.980643890645482
GO:0035673	oligopeptide transmembrane transporter activity	2/2658	13/18639	0.153846153846154	1.07883313075187	0.572174717394446	0.980643890645482
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/2658	13/18639	0.153846153846154	1.07883313075187	0.572174717394446	0.980643890645482
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/2658	13/18639	0.153846153846154	1.07883313075187	0.572174717394446	0.980643890645482
GO:0070123	transforming growth factor beta receptor activity, type III	2/2658	13/18639	0.153846153846154	1.07883313075187	0.572174717394446	0.980643890645482
GO:0089720	caspase binding	2/2658	13/18639	0.153846153846154	1.07883313075187	0.572174717394446	0.980643890645482
GO:0046625	sphingolipid binding	4/2658	28/18639	0.142857142857143	1.00177362141245	0.580331744202	0.991868936766299
GO:0050698	proteoglycan sulfotransferase activity	4/2658	28/18639	0.142857142857143	1.00177362141245	0.580331744202	0.991868936766299
GO:0019955	cytokine binding	20/2658	144/18639	0.138888888888889	0.973946576373213	0.587366660939874	1
GO:0008200	ion channel inhibitor activity	6/2658	43/18639	0.13953488372093	0.978476560449367	0.589277403262654	1
GO:0019843	rRNA binding	9/2658	65/18639	0.138461538461538	0.97094981767668	0.59213468926152	1
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	5/2658	36/18639	0.138888888888889	0.973946576373213	0.597839333366596	1
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	5/2658	36/18639	0.138888888888889	0.973946576373213	0.597839333366596	1
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	5/2658	36/18639	0.138888888888889	0.973946576373213	0.597839333366596	1
GO:0099106	ion channel regulator activity	22/2658	160/18639	0.1375	0.964207110609481	0.608064708004667	1
GO:0004629	phospholipase C activity	4/2658	29/18639	0.137931034482759	0.967229703432708	0.609287442647984	1
GO:0004065	arylsulfatase activity	2/2658	14/18639	0.142857142857143	1.00177362141245	0.613914251773421	1
GO:0005545	1-phosphatidylinositol binding	2/2658	14/18639	0.142857142857143	1.00177362141245	0.613914251773421	1
GO:0008191	metalloendopeptidase inhibitor activity	2/2658	14/18639	0.142857142857143	1.00177362141245	0.613914251773421	1
GO:0008195	phosphatidate phosphatase activity	2/2658	14/18639	0.142857142857143	1.00177362141245	0.613914251773421	1
GO:0008494	translation activator activity	2/2658	14/18639	0.142857142857143	1.00177362141245	0.613914251773421	1
GO:0030983	mismatched DNA binding	2/2658	14/18639	0.142857142857143	1.00177362141245	0.613914251773421	1
GO:0032036	myosin heavy chain binding	2/2658	14/18639	0.142857142857143	1.00177362141245	0.613914251773421	1
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/2658	14/18639	0.142857142857143	1.00177362141245	0.613914251773421	1
GO:0016247	channel regulator activity	23/2658	168/18639	0.136904761904762	0.960033053853596	0.617663986578898	1
GO:0004879	nuclear receptor activity	8/2658	59/18639	0.135593220338983	0.950835979645713	0.617889769794493	1
GO:0015459	potassium channel regulator activity	8/2658	59/18639	0.135593220338983	0.950835979645713	0.617889769794493	1
GO:0008093	cytoskeletal anchor activity	3/2658	22/18639	0.136363636363636	0.956238456802791	0.625745162971507	1
GO:0034062	5'-3' RNA polymerase activity	3/2658	22/18639	0.136363636363636	0.956238456802791	0.625745162971507	1
GO:0097747	RNA polymerase activity	3/2658	22/18639	0.136363636363636	0.956238456802791	0.625745162971507	1
GO:0008173	RNA methyltransferase activity	9/2658	67/18639	0.134328358208955	0.941966241029615	0.629981207237061	1
GO:0046915	transition metal ion transmembrane transporter activity	6/2658	45/18639	0.133333333333333	0.934988713318284	0.635354849311164	1
GO:0015215	nucleotide transmembrane transporter activity	4/2658	30/18639	0.133333333333333	0.934988713318284	0.636978296629962	1
GO:0016769	transferase activity, transferring nitrogenous groups	4/2658	30/18639	0.133333333333333	0.934988713318284	0.636978296629962	1
GO:0141108	transporter regulator activity	23/2658	170/18639	0.135294117647059	0.948738547337671	0.641152250388314	1
GO:0005200	structural constituent of cytoskeleton	15/2658	112/18639	0.133928571428571	0.93916277007417	0.644772853554385	1
GO:0004864	protein phosphatase inhibitor activity	7/2658	53/18639	0.132075471698113	0.926168065079433	0.646387407702205	1
GO:0008146	sulfotransferase activity	7/2658	53/18639	0.132075471698113	0.926168065079433	0.646387407702205	1
GO:0043531	ADP binding	5/2658	38/18639	0.131578947368421	0.922686230248307	0.647449150187927	1
GO:0004467	long-chain fatty acid-CoA ligase activity	2/2658	15/18639	0.133333333333333	0.934988713318284	0.652454430371129	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/2658	15/18639	0.133333333333333	0.934988713318284	0.652454430371129	1
GO:0004953	icosanoid receptor activity	2/2658	15/18639	0.133333333333333	0.934988713318284	0.652454430371129	1
GO:0005041	low-density lipoprotein particle receptor activity	2/2658	15/18639	0.133333333333333	0.934988713318284	0.652454430371129	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	2/2658	15/18639	0.133333333333333	0.934988713318284	0.652454430371129	1
GO:0008252	nucleotidase activity	2/2658	15/18639	0.133333333333333	0.934988713318284	0.652454430371129	1
GO:0010181	FMN binding	2/2658	15/18639	0.133333333333333	0.934988713318284	0.652454430371129	1
GO:0017081	chloride channel regulator activity	2/2658	15/18639	0.133333333333333	0.934988713318284	0.652454430371129	1
GO:0031386	protein tag activity	2/2658	15/18639	0.133333333333333	0.934988713318284	0.652454430371129	1
GO:0045504	dynein heavy chain binding	2/2658	15/18639	0.133333333333333	0.934988713318284	0.652454430371129	1
GO:0050780	dopamine receptor binding	2/2658	15/18639	0.133333333333333	0.934988713318284	0.652454430371129	1
GO:0055105	ubiquitin-protein transferase inhibitor activity	2/2658	15/18639	0.133333333333333	0.934988713318284	0.652454430371129	1
GO:0140776	protein-containing complex destabilizing activity	2/2658	15/18639	0.133333333333333	0.934988713318284	0.652454430371129	1
GO:0141047	molecular tag activity	2/2658	15/18639	0.133333333333333	0.934988713318284	0.652454430371129	1
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	8/2658	61/18639	0.131147540983607	0.919661029493395	0.656496683260085	1
GO:0000295	adenine nucleotide transmembrane transporter activity	3/2658	23/18639	0.130434782608696	0.914662871724409	0.656639401270806	1
GO:0004602	glutathione peroxidase activity	3/2658	23/18639	0.130434782608696	0.914662871724409	0.656639401270806	1
GO:0016493	C-C chemokine receptor activity	3/2658	23/18639	0.130434782608696	0.914662871724409	0.656639401270806	1
GO:0016849	phosphorus-oxygen lyase activity	3/2658	23/18639	0.130434782608696	0.914662871724409	0.656639401270806	1
GO:0051536	iron-sulfur cluster binding	10/2658	76/18639	0.131578947368421	0.922686230248307	0.658045519584109	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	12/2658	91/18639	0.131868131868132	0.924714112073029	0.660688105295937	1
GO:0016878	acid-thiol ligase activity	4/2658	31/18639	0.129032258064516	0.904827787082211	0.663357860597363	1
GO:0051540	metal cluster binding	10/2658	77/18639	0.12987012987013	0.910703292193134	0.6746004291052	1
GO:0005504	fatty acid binding	6/2658	47/18639	0.127659574468085	0.89520195956006	0.678227833575485	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	24/2658	181/18639	0.132596685082873	0.929823029819288	0.682396071818319	1
GO:0008374	O-acyltransferase activity	7/2658	55/18639	0.127272727272727	0.892489226349271	0.685576692764205	1
GO:0005315	phosphate transmembrane transporter activity	3/2658	24/18639	0.125	0.876551918735892	0.685650204989029	1
GO:0060229	lipase activator activity	3/2658	24/18639	0.125	0.876551918735892	0.685650204989029	1
GO:0140612	DNA damage sensor activity	3/2658	24/18639	0.125	0.876551918735892	0.685650204989029	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/2658	16/18639	0.125	0.876551918735892	0.687858607691188	1
GO:0005024	transforming growth factor beta receptor activity	2/2658	16/18639	0.125	0.876551918735892	0.687858607691188	1
GO:0008296	3'-5'-DNA exonuclease activity	2/2658	16/18639	0.125	0.876551918735892	0.687858607691188	1
GO:0015562	efflux transmembrane transporter activity	2/2658	16/18639	0.125	0.876551918735892	0.687858607691188	1
GO:0017070	U6 snRNA binding	2/2658	16/18639	0.125	0.876551918735892	0.687858607691188	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/2658	16/18639	0.125	0.876551918735892	0.687858607691188	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/2658	16/18639	0.125	0.876551918735892	0.687858607691188	1
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	2/2658	16/18639	0.125	0.876551918735892	0.687858607691188	1
GO:0003730	mRNA 3'-UTR binding	35/2658	262/18639	0.133587786259542	0.936773042923854	0.689263929466643	1
GO:0015036	disulfide oxidoreductase activity	5/2658	40/18639	0.125	0.876551918735892	0.693009081883572	1
GO:0050660	flavin adenine dinucleotide binding	11/2658	86/18639	0.127906976744186	0.896936847078587	0.697956920664776	1
GO:0140101	catalytic activity, acting on a tRNA	18/2658	139/18639	0.129496402877698	0.908082563294737	0.707243610609798	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	4/2658	33/18639	0.121212121212121	0.849989739380259	0.712087932807519	1
GO:0008081	phosphoric diester hydrolase activity	11/2658	87/18639	0.126436781609195	0.886627228146649	0.71264893779594	1
GO:0003707	nuclear steroid receptor activity	3/2658	25/18639	0.12	0.841489841986456	0.712784476608271	1
GO:0001530	lipopolysaccharide binding	5/2658	41/18639	0.121951219512195	0.855172603644772	0.714214203911083	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	5/2658	41/18639	0.121951219512195	0.855172603644772	0.714214203911083	1
GO:0017080	sodium channel regulator activity	5/2658	41/18639	0.121951219512195	0.855172603644772	0.714214203911083	1
GO:0140318	protein transporter activity	5/2658	41/18639	0.121951219512195	0.855172603644772	0.714214203911083	1
GO:0140828	metal cation:monoatomic cation antiporter activity	5/2658	41/18639	0.121951219512195	0.855172603644772	0.714214203911083	1
GO:0004659	prenyltransferase activity	2/2658	17/18639	0.117647058823529	0.824990041163192	0.720237121673217	1
GO:0008484	sulfuric ester hydrolase activity	2/2658	17/18639	0.117647058823529	0.824990041163192	0.720237121673217	1
GO:0015278	intracellularly gated calcium channel activity	2/2658	17/18639	0.117647058823529	0.824990041163192	0.720237121673217	1
GO:0017110	nucleoside diphosphate phosphatase activity	2/2658	17/18639	0.117647058823529	0.824990041163192	0.720237121673217	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/2658	17/18639	0.117647058823529	0.824990041163192	0.720237121673217	1
GO:0031489	myosin V binding	2/2658	17/18639	0.117647058823529	0.824990041163192	0.720237121673217	1
GO:0015932	nucleobase-containing compound transmembrane transporter activity	7/2658	57/18639	0.12280701754386	0.86117381489842	0.721872341373028	1
GO:0038024	cargo receptor activity	8/2658	65/18639	0.123076923076923	0.863066504601493	0.726404827625289	1
GO:0004521	RNA endonuclease activity	9/2658	73/18639	0.123287671232877	0.864544358205263	0.731108921582781	1
GO:0019894	kinesin binding	5/2658	42/18639	0.119047619047619	0.83481135117704	0.734359849475814	1
GO:0015605	organophosphate ester transmembrane transporter activity	6/2658	50/18639	0.12	0.841489841986456	0.736124688224372	1
GO:0001637	G protein-coupled chemoattractant receptor activity	3/2658	26/18639	0.115384615384615	0.8091248480639	0.738071418226051	1
GO:0004950	chemokine receptor activity	3/2658	26/18639	0.115384615384615	0.8091248480639	0.738071418226051	1
GO:0008157	protein phosphatase 1 binding	3/2658	26/18639	0.115384615384615	0.8091248480639	0.738071418226051	1
GO:0015145	monosaccharide transmembrane transporter activity	3/2658	26/18639	0.115384615384615	0.8091248480639	0.738071418226051	1
GO:0015216	purine nucleotide transmembrane transporter activity	3/2658	26/18639	0.115384615384615	0.8091248480639	0.738071418226051	1
GO:0030507	spectrin binding	3/2658	26/18639	0.115384615384615	0.8091248480639	0.738071418226051	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	7/2658	58/18639	0.120689655172414	0.84632599050362	0.738908694968005	1
GO:0004519	endonuclease activity	16/2658	127/18639	0.125984251968504	0.883453902347985	0.74139416414514	1
GO:0000400	four-way junction DNA binding	2/2658	18/18639	0.111111111111111	0.77915726109857	0.749732614309718	1
GO:0000900	mRNA regulatory element binding translation repressor activity	2/2658	18/18639	0.111111111111111	0.77915726109857	0.749732614309718	1
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/2658	18/18639	0.111111111111111	0.77915726109857	0.749732614309718	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/2658	18/18639	0.111111111111111	0.77915726109857	0.749732614309718	1
GO:0008409	5'-3' exonuclease activity	2/2658	18/18639	0.111111111111111	0.77915726109857	0.749732614309718	1
GO:0015172	acidic amino acid transmembrane transporter activity	2/2658	18/18639	0.111111111111111	0.77915726109857	0.749732614309718	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/2658	18/18639	0.111111111111111	0.77915726109857	0.749732614309718	1
GO:0030228	lipoprotein particle receptor activity	2/2658	18/18639	0.111111111111111	0.77915726109857	0.749732614309718	1
GO:0035615	clathrin adaptor activity	2/2658	18/18639	0.111111111111111	0.77915726109857	0.749732614309718	1
GO:0016830	carbon-carbon lyase activity	6/2658	51/18639	0.117647058823529	0.824990041163192	0.753679237752182	1
GO:0001786	phosphatidylserine binding	7/2658	59/18639	0.11864406779661	0.831981482189999	0.755199704125978	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	7/2658	59/18639	0.11864406779661	0.831981482189999	0.755199704125978	1
GO:0015399	primary active transmembrane transporter activity	21/2658	166/18639	0.126506024096386	0.887112785226685	0.75617144129331	1
GO:0004364	glutathione transferase activity	3/2658	27/18639	0.111111111111111	0.77915726109857	0.761558036836588	1
GO:0008320	protein transmembrane transporter activity	3/2658	27/18639	0.111111111111111	0.77915726109857	0.761558036836588	1
GO:0016405	CoA-ligase activity	3/2658	27/18639	0.111111111111111	0.77915726109857	0.761558036836588	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	3/2658	27/18639	0.111111111111111	0.77915726109857	0.761558036836588	1
GO:0004033	aldo-keto reductase (NADPH) activity	4/2658	36/18639	0.111111111111111	0.77915726109857	0.775137546618624	1
GO:0004190	aspartic-type endopeptidase activity	4/2658	36/18639	0.111111111111111	0.77915726109857	0.775137546618624	1
GO:0003774	cytoskeletal motor activity	19/2658	153/18639	0.124183006535948	0.870822821227814	0.776157600848886	1
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/2658	19/18639	0.105263157894737	0.738148984198646	0.776508581099114	1
GO:0005520	insulin-like growth factor binding	2/2658	19/18639	0.105263157894737	0.738148984198646	0.776508581099114	1
GO:0030506	ankyrin binding	2/2658	19/18639	0.105263157894737	0.738148984198646	0.776508581099114	1
GO:0034987	immunoglobulin receptor binding	2/2658	19/18639	0.105263157894737	0.738148984198646	0.776508581099114	1
GO:0042577	lipid phosphatase activity	2/2658	19/18639	0.105263157894737	0.738148984198646	0.776508581099114	1
GO:0046527	glucosyltransferase activity	2/2658	19/18639	0.105263157894737	0.738148984198646	0.776508581099114	1
GO:0097001	ceramide binding	2/2658	19/18639	0.105263157894737	0.738148984198646	0.776508581099114	1
GO:0051119	sugar transmembrane transporter activity	3/2658	28/18639	0.107142857142857	0.751330216059336	0.783305191952738	1
GO:0000182	rDNA binding	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0004382	GDP phosphatase activity	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0004935	adrenergic receptor activity	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0008519	ammonium channel activity	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0015187	glycine transmembrane transporter activity	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0015643	toxic substance binding	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0016783	sulfurtransferase activity	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0016868	intramolecular phosphotransferase activity	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0019911	structural constituent of myelin sheath	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0031419	cobalamin binding	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0035256	G protein-coupled glutamate receptor binding	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0047429	nucleoside triphosphate diphosphatase activity	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0050308	sugar-phosphatase activity	1/2658	10/18639	0.1	0.701241534988713	0.78539542505144	1
GO:0070001	aspartic-type peptidase activity	4/2658	37/18639	0.108108108108108	0.758098956744555	0.793562266014854	1
GO:0001614	purinergic nucleotide receptor activity	2/2658	20/18639	0.1	0.701241534988713	0.800740527461128	1
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	2/2658	20/18639	0.1	0.701241534988713	0.800740527461128	1
GO:0016502	nucleotide receptor activity	2/2658	20/18639	0.1	0.701241534988713	0.800740527461128	1
GO:0031418	L-ascorbic acid binding	2/2658	20/18639	0.1	0.701241534988713	0.800740527461128	1
GO:0016209	antioxidant activity	10/2658	86/18639	0.116279069767442	0.815397133707806	0.800895362445168	1
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	6/2658	54/18639	0.111111111111111	0.77915726109857	0.801174063999736	1
GO:0004181	metallocarboxypeptidase activity	3/2658	29/18639	0.103448275862069	0.725422277574531	0.803384163026364	1
GO:0004180	carboxypeptidase activity	5/2658	46/18639	0.108695652173913	0.762219059770341	0.804524826111935	1
GO:0000146	microfilament motor activity	4/2658	38/18639	0.105263157894737	0.738148984198646	0.810752044347434	1
GO:0042887	amide transmembrane transporter activity	4/2658	38/18639	0.105263157894737	0.738148984198646	0.810752044347434	1
GO:0005507	copper ion binding	7/2658	63/18639	0.111111111111111	0.77915726109857	0.813005716252765	1
GO:0004175	endopeptidase activity	52/2658	405/18639	0.128395061728395	0.900359501713904	0.814790423769769	1
GO:0004016	adenylate cyclase activity	1/2658	11/18639	0.0909090909090909	0.637492304535194	0.816015370309547	1
GO:0005536	D-glucose binding	1/2658	11/18639	0.0909090909090909	0.637492304535194	0.816015370309547	1
GO:0008271	secondary active sulfate transmembrane transporter activity	1/2658	11/18639	0.0909090909090909	0.637492304535194	0.816015370309547	1
GO:0008432	JUN kinase binding	1/2658	11/18639	0.0909090909090909	0.637492304535194	0.816015370309547	1
GO:0010854	adenylate cyclase regulator activity	1/2658	11/18639	0.0909090909090909	0.637492304535194	0.816015370309547	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/2658	11/18639	0.0909090909090909	0.637492304535194	0.816015370309547	1
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/2658	11/18639	0.0909090909090909	0.637492304535194	0.816015370309547	1
GO:0019203	carbohydrate phosphatase activity	1/2658	11/18639	0.0909090909090909	0.637492304535194	0.816015370309547	1
GO:0019206	nucleoside kinase activity	1/2658	11/18639	0.0909090909090909	0.637492304535194	0.816015370309547	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/2658	11/18639	0.0909090909090909	0.637492304535194	0.816015370309547	1
GO:0050786	RAGE receptor binding	1/2658	11/18639	0.0909090909090909	0.637492304535194	0.816015370309547	1
GO:0070697	activin receptor binding	1/2658	11/18639	0.0909090909090909	0.637492304535194	0.816015370309547	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/2658	11/18639	0.0909090909090909	0.637492304535194	0.816015370309547	1
GO:1990948	ubiquitin ligase inhibitor activity	1/2658	11/18639	0.0909090909090909	0.637492304535194	0.816015370309547	1
GO:0001968	fibronectin binding	3/2658	30/18639	0.1	0.701241534988713	0.821873703737075	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	3/2658	30/18639	0.1	0.701241534988713	0.821873703737075	1
GO:0098918	structural constituent of synapse	3/2658	30/18639	0.1	0.701241534988713	0.821873703737075	1
GO:0015297	antiporter activity	16/2658	135/18639	0.118518518518519	0.831101078505142	0.822089295596236	1
GO:0001846	opsonin binding	2/2658	21/18639	0.0952380952380952	0.667849080941632	0.822609221849533	1
GO:0009975	cyclase activity	2/2658	21/18639	0.0952380952380952	0.667849080941632	0.822609221849533	1
GO:0010314	phosphatidylinositol-5-phosphate binding	2/2658	21/18639	0.0952380952380952	0.667849080941632	0.822609221849533	1
GO:0015174	basic amino acid transmembrane transporter activity	2/2658	21/18639	0.0952380952380952	0.667849080941632	0.822609221849533	1
GO:0019200	carbohydrate kinase activity	2/2658	21/18639	0.0952380952380952	0.667849080941632	0.822609221849533	1
GO:0048306	calcium-dependent protein binding	9/2658	80/18639	0.1125	0.788896726862303	0.823314899545643	1
GO:0000217	DNA secondary structure binding	4/2658	39/18639	0.102564102564103	0.719222087167911	0.826752359250084	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/2658	39/18639	0.102564102564103	0.719222087167911	0.826752359250084	1
GO:0032266	phosphatidylinositol-3-phosphate binding	5/2658	48/18639	0.104166666666667	0.73045993227991	0.833649114761405	1
GO:0015101	organic cation transmembrane transporter activity	9/2658	81/18639	0.111111111111111	0.77915726109857	0.834244594460372	1
GO:0016757	glycosyltransferase activity	33/2658	267/18639	0.123595505617978	0.866703020772567	0.837125234632083	1
GO:0015144	carbohydrate transmembrane transporter activity	4/2658	40/18639	0.1	0.701241534988713	0.841612723401919	1
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	4/2658	40/18639	0.1	0.701241534988713	0.841612723401919	1
GO:0071949	FAD binding	4/2658	40/18639	0.1	0.701241534988713	0.841612723401919	1
GO:0003720	telomerase activity	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0005025	transforming growth factor beta receptor activity, type I	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0005026	transforming growth factor beta receptor activity, type II	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0005247	voltage-gated chloride channel activity	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0005436	sodium:phosphate symporter activity	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0015132	prostaglandin transmembrane transporter activity	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0015368	calcium:monoatomic cation antiporter activity	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0016208	AMP binding	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0016361	activin receptor activity, type I	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0016362	activin receptor activity, type II	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0016801	hydrolase activity, acting on ether bonds	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0016803	ether hydrolase activity	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0017002	activin receptor activity	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0031543	peptidyl-proline dioxygenase activity	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0035251	UDP-glucosyltransferase activity	1/2658	12/18639	0.0833333333333333	0.584367945823928	0.842267847532933	1
GO:0008649	rRNA methyltransferase activity	2/2658	22/18639	0.0909090909090909	0.637492304535194	0.842295627737336	1
GO:0015377	chloride:monoatomic cation symporter activity	2/2658	22/18639	0.0909090909090909	0.637492304535194	0.842295627737336	1
GO:0033691	sialic acid binding	2/2658	22/18639	0.0909090909090909	0.637492304535194	0.842295627737336	1
GO:0042626	ATPase-coupled transmembrane transporter activity	11/2658	98/18639	0.112244897959184	0.787107845395495	0.843458449621552	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	15/2658	130/18639	0.115384615384615	0.8091248480639	0.845874558893261	1
GO:0015106	bicarbonate transmembrane transporter activity	3/2658	32/18639	0.09375	0.657413939051919	0.854422298112305	1
GO:0005319	lipid transporter activity	21/2658	178/18639	0.117977528089888	0.827307428919269	0.854462232224857	1
GO:0015085	calcium ion transmembrane transporter activity	17/2658	147/18639	0.115646258503401	0.810959598286267	0.855801721671425	1
GO:0005283	amino acid:sodium symporter activity	2/2658	23/18639	0.0869565217391304	0.609775247816272	0.859977173115101	1
GO:0008171	O-methyltransferase activity	2/2658	23/18639	0.0869565217391304	0.609775247816272	0.859977173115101	1
GO:0099186	structural constituent of postsynapse	2/2658	23/18639	0.0869565217391304	0.609775247816272	0.859977173115101	1
GO:0140102	catalytic activity, acting on a rRNA	2/2658	23/18639	0.0869565217391304	0.609775247816272	0.859977173115101	1
GO:0140103	catalytic activity, acting on a glycoprotein	2/2658	23/18639	0.0869565217391304	0.609775247816272	0.859977173115101	1
GO:0002161	aminoacyl-tRNA editing activity	1/2658	13/18639	0.0769230769230769	0.539416565375933	0.864775608377806	1
GO:0003964	RNA-directed DNA polymerase activity	1/2658	13/18639	0.0769230769230769	0.539416565375933	0.864775608377806	1
GO:0005542	folic acid binding	1/2658	13/18639	0.0769230769230769	0.539416565375933	0.864775608377806	1
GO:0009982	pseudouridine synthase activity	1/2658	13/18639	0.0769230769230769	0.539416565375933	0.864775608377806	1
GO:0031432	titin binding	1/2658	13/18639	0.0769230769230769	0.539416565375933	0.864775608377806	1
GO:0031994	insulin-like growth factor I binding	1/2658	13/18639	0.0769230769230769	0.539416565375933	0.864775608377806	1
GO:0035325	Toll-like receptor binding	1/2658	13/18639	0.0769230769230769	0.539416565375933	0.864775608377806	1
GO:0045159	myosin II binding	1/2658	13/18639	0.0769230769230769	0.539416565375933	0.864775608377806	1
GO:0061459	L-arginine transmembrane transporter activity	1/2658	13/18639	0.0769230769230769	0.539416565375933	0.864775608377806	1
GO:0070700	BMP receptor binding	1/2658	13/18639	0.0769230769230769	0.539416565375933	0.864775608377806	1
GO:0071714	icosanoid transmembrane transporter activity	1/2658	13/18639	0.0769230769230769	0.539416565375933	0.864775608377806	1
GO:0071837	HMG box domain binding	1/2658	13/18639	0.0769230769230769	0.539416565375933	0.864775608377806	1
GO:1901338	catecholamine binding	1/2658	13/18639	0.0769230769230769	0.539416565375933	0.864775608377806	1
GO:0004520	DNA endonuclease activity	4/2658	42/18639	0.0952380952380952	0.667849080941632	0.868125082303429	1
GO:0030296	protein tyrosine kinase activator activity	3/2658	33/18639	0.0909090909090909	0.637492304535194	0.868655734642783	1
GO:0016597	amino acid binding	5/2658	51/18639	0.0980392156862745	0.687491700969327	0.870587203836797	1
GO:0004622	lysophospholipase activity	2/2658	24/18639	0.0833333333333333	0.584367945823928	0.87582507930838	1
GO:0015149	hexose transmembrane transporter activity	2/2658	24/18639	0.0833333333333333	0.584367945823928	0.87582507930838	1
GO:0015295	solute:proton symporter activity	2/2658	24/18639	0.0833333333333333	0.584367945823928	0.87582507930838	1
GO:0050431	transforming growth factor beta binding	2/2658	24/18639	0.0833333333333333	0.584367945823928	0.87582507930838	1
GO:0055056	D-glucose transmembrane transporter activity	2/2658	24/18639	0.0833333333333333	0.584367945823928	0.87582507930838	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/2658	24/18639	0.0833333333333333	0.584367945823928	0.87582507930838	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	9/2658	86/18639	0.104651162790698	0.733857420337026	0.881162648630945	1
GO:0008376	acetylgalactosaminyltransferase activity	3/2658	34/18639	0.0882352941176471	0.618742530872394	0.881645368616602	1
GO:0015035	protein-disulfide reductase activity	3/2658	34/18639	0.0882352941176471	0.618742530872394	0.881645368616602	1
GO:0016831	carboxy-lyase activity	3/2658	34/18639	0.0882352941176471	0.618742530872394	0.881645368616602	1
GO:0051427	hormone receptor binding	3/2658	34/18639	0.0882352941176471	0.618742530872394	0.881645368616602	1
GO:0090482	vitamin transmembrane transporter activity	3/2658	34/18639	0.0882352941176471	0.618742530872394	0.881645368616602	1
GO:0016874	ligase activity	19/2658	167/18639	0.11377245508982	0.797819710466201	0.883800030987141	1
GO:0005344	oxygen carrier activity	1/2658	14/18639	0.0714285714285714	0.500886810706224	0.884072635808913	1
GO:0008559	ABC-type xenobiotic transporter activity	1/2658	14/18639	0.0714285714285714	0.500886810706224	0.884072635808913	1
GO:0015386	potassium:proton antiporter activity	1/2658	14/18639	0.0714285714285714	0.500886810706224	0.884072635808913	1
GO:0031404	chloride ion binding	1/2658	14/18639	0.0714285714285714	0.500886810706224	0.884072635808913	1
GO:0042813	Wnt receptor activity	1/2658	14/18639	0.0714285714285714	0.500886810706224	0.884072635808913	1
GO:0043176	amine binding	1/2658	14/18639	0.0714285714285714	0.500886810706224	0.884072635808913	1
GO:0046030	inositol trisphosphate phosphatase activity	1/2658	14/18639	0.0714285714285714	0.500886810706224	0.884072635808913	1
GO:0098821	BMP receptor activity	1/2658	14/18639	0.0714285714285714	0.500886810706224	0.884072635808913	1
GO:1901474	azole transmembrane transporter activity	1/2658	14/18639	0.0714285714285714	0.500886810706224	0.884072635808913	1
GO:1901612	cardiolipin binding	1/2658	14/18639	0.0714285714285714	0.500886810706224	0.884072635808913	1
GO:0001848	complement binding	2/2658	25/18639	0.08	0.560993227990971	0.890002523021433	1
GO:0005537	D-mannose binding	2/2658	25/18639	0.08	0.560993227990971	0.890002523021433	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/2658	25/18639	0.08	0.560993227990971	0.890002523021433	1
GO:0015645	fatty acid ligase activity	2/2658	25/18639	0.08	0.560993227990971	0.890002523021433	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	2/2658	25/18639	0.08	0.560993227990971	0.890002523021433	1
GO:0120515	fatty acid-CoA ligase activity	2/2658	25/18639	0.08	0.560993227990971	0.890002523021433	1
GO:1901505	carbohydrate derivative transmembrane transporter activity	5/2658	53/18639	0.0943396226415094	0.661548617913881	0.891150909684384	1
GO:0015370	solute:sodium symporter activity	8/2658	79/18639	0.10126582278481	0.710118010115153	0.892205385255156	1
GO:0005343	organic acid:sodium symporter activity	3/2658	35/18639	0.0857142857142857	0.601064172847468	0.893477333316954	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	9/2658	88/18639	0.102272727272727	0.717178842602093	0.89659666983506	1
GO:0050661	NADP binding	5/2658	54/18639	0.0925925925925926	0.649297717582142	0.900332220468532	1
GO:0051287	NAD binding	5/2658	54/18639	0.0925925925925926	0.649297717582142	0.900332220468532	1
GO:0004089	carbonate dehydratase activity	1/2658	15/18639	0.0666666666666667	0.467494356659142	0.900616793340183	1
GO:0005523	tropomyosin binding	1/2658	15/18639	0.0666666666666667	0.467494356659142	0.900616793340183	1
GO:0015116	sulfate transmembrane transporter activity	1/2658	15/18639	0.0666666666666667	0.467494356659142	0.900616793340183	1
GO:0015250	water channel activity	1/2658	15/18639	0.0666666666666667	0.467494356659142	0.900616793340183	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/2658	15/18639	0.0666666666666667	0.467494356659142	0.900616793340183	1
GO:0016846	carbon-sulfur lyase activity	1/2658	15/18639	0.0666666666666667	0.467494356659142	0.900616793340183	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/2658	15/18639	0.0666666666666667	0.467494356659142	0.900616793340183	1
GO:0031005	filamin binding	1/2658	15/18639	0.0666666666666667	0.467494356659142	0.900616793340183	1
GO:0034483	heparan sulfate sulfotransferase activity	1/2658	15/18639	0.0666666666666667	0.467494356659142	0.900616793340183	1
GO:0047372	monoacylglycerol lipase activity	1/2658	15/18639	0.0666666666666667	0.467494356659142	0.900616793340183	1
GO:0048531	beta-1,3-galactosyltransferase activity	1/2658	15/18639	0.0666666666666667	0.467494356659142	0.900616793340183	1
GO:0051371	muscle alpha-actinin binding	1/2658	15/18639	0.0666666666666667	0.467494356659142	0.900616793340183	1
GO:0004529	DNA exonuclease activity	2/2658	26/18639	0.0769230769230769	0.539416565375933	0.902663448421048	1
GO:0050750	low-density lipoprotein particle receptor binding	2/2658	26/18639	0.0769230769230769	0.539416565375933	0.902663448421048	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/2658	36/18639	0.0833333333333333	0.584367945823928	0.904235495744075	1
GO:0004536	DNA nuclease activity	6/2658	64/18639	0.09375	0.657413939051919	0.90958232569122	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	4/2658	46/18639	0.0869565217391304	0.609775247816272	0.90985729741447	1
GO:0015252	proton channel activity	2/2658	27/18639	0.0740740740740741	0.519438174065713	0.913951881347805	1
GO:0043394	proteoglycan binding	3/2658	37/18639	0.0810810810810811	0.568574217558416	0.914000780720183	1
GO:0005149	interleukin-1 receptor binding	1/2658	16/18639	0.0625	0.438275959367946	0.91480067238345	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/2658	16/18639	0.0625	0.438275959367946	0.91480067238345	1
GO:0015378	sodium:chloride symporter activity	1/2658	16/18639	0.0625	0.438275959367946	0.91480067238345	1
GO:0022841	potassium ion leak channel activity	1/2658	16/18639	0.0625	0.438275959367946	0.91480067238345	1
GO:0015294	solute:monoatomic cation symporter activity	12/2658	116/18639	0.103448275862069	0.725422277574531	0.915352911798653	1
GO:0017171	serine hydrolase activity	22/2658	198/18639	0.111111111111111	0.77915726109857	0.919463001501081	1
GO:0004620	phospholipase activity	11/2658	109/18639	0.100917431192661	0.707674943566591	0.922649815754382	1
GO:0004601	peroxidase activity	5/2658	57/18639	0.087719298245614	0.615124153498871	0.92394559079464	1
GO:0016866	intramolecular transferase activity	2/2658	28/18639	0.0714285714285714	0.500886810706224	0.924001626685887	1
GO:0051537	2 iron, 2 sulfur cluster binding	2/2658	28/18639	0.0714285714285714	0.500886810706224	0.924001626685887	1
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	2/2658	28/18639	0.0714285714285714	0.500886810706224	0.924001626685887	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	1/2658	17/18639	0.0588235294117647	0.412495020581596	0.926960894302839	1
GO:0008569	minus-end-directed microtubule motor activity	1/2658	17/18639	0.0588235294117647	0.412495020581596	0.926960894302839	1
GO:0009881	photoreceptor activity	1/2658	17/18639	0.0588235294117647	0.412495020581596	0.926960894302839	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/2658	17/18639	0.0588235294117647	0.412495020581596	0.926960894302839	1
GO:0038191	neuropilin binding	1/2658	17/18639	0.0588235294117647	0.412495020581596	0.926960894302839	1
GO:0045236	CXCR chemokine receptor binding	1/2658	17/18639	0.0588235294117647	0.412495020581596	0.926960894302839	1
GO:0070492	oligosaccharide binding	1/2658	17/18639	0.0588235294117647	0.412495020581596	0.926960894302839	1
GO:0015171	amino acid transmembrane transporter activity	10/2658	102/18639	0.0980392156862745	0.687491700969327	0.930213014512345	1
GO:0005416	amino acid:monoatomic cation symporter activity	2/2658	29/18639	0.0689655172413793	0.483614851716354	0.93293625362363	1
GO:0035250	UDP-galactosyltransferase activity	2/2658	29/18639	0.0689655172413793	0.483614851716354	0.93293625362363	1
GO:0043236	laminin binding	2/2658	29/18639	0.0689655172413793	0.483614851716354	0.93293625362363	1
GO:0051861	glycolipid binding	2/2658	29/18639	0.0689655172413793	0.483614851716354	0.93293625362363	1
GO:0099604	ligand-gated calcium channel activity	2/2658	29/18639	0.0689655172413793	0.483614851716354	0.93293625362363	1
GO:0061134	peptidase regulator activity	25/2658	226/18639	0.110619469026549	0.775709662598134	0.934496574889125	1
GO:0008194	UDP-glycosyltransferase activity	15/2658	145/18639	0.103448275862069	0.725422277574531	0.934832819343331	1
GO:0008236	serine-type peptidase activity	21/2658	194/18639	0.108247422680412	0.759075888389844	0.934833638807012	1
GO:0005372	water transmembrane transporter activity	1/2658	18/18639	0.0555555555555556	0.389578630549285	0.937386087243611	1
GO:0015373	monoatomic anion:sodium symporter activity	1/2658	18/18639	0.0555555555555556	0.389578630549285	0.937386087243611	1
GO:0016854	racemase and epimerase activity	1/2658	18/18639	0.0555555555555556	0.389578630549285	0.937386087243611	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/2658	18/18639	0.0555555555555556	0.389578630549285	0.937386087243611	1
GO:0017128	phospholipid scramblase activity	1/2658	18/18639	0.0555555555555556	0.389578630549285	0.937386087243611	1
GO:0032393	MHC class I receptor activity	1/2658	18/18639	0.0555555555555556	0.389578630549285	0.937386087243611	1
GO:0034185	apolipoprotein binding	1/2658	18/18639	0.0555555555555556	0.389578630549285	0.937386087243611	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/2658	18/18639	0.0555555555555556	0.389578630549285	0.937386087243611	1
GO:0050811	GABA receptor binding	1/2658	18/18639	0.0555555555555556	0.389578630549285	0.937386087243611	1
GO:0099602	neurotransmitter receptor regulator activity	1/2658	18/18639	0.0555555555555556	0.389578630549285	0.937386087243611	1
GO:0015293	symporter activity	15/2658	146/18639	0.102739726027397	0.720453631837719	0.938760263247482	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/2658	30/18639	0.0666666666666667	0.467494356659142	0.940869292901241	1
GO:0033612	receptor serine/threonine kinase binding	2/2658	30/18639	0.0666666666666667	0.467494356659142	0.940869292901241	1
GO:0016853	isomerase activity	19/2658	180/18639	0.105555555555556	0.740199398043642	0.942505549372244	1
GO:0033293	monocarboxylic acid binding	7/2658	79/18639	0.0886075949367089	0.621353258850759	0.945795536341479	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/2658	19/18639	0.0526315789473684	0.369074492099323	0.946323726473861	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/2658	19/18639	0.0526315789473684	0.369074492099323	0.946323726473861	1
GO:0015245	fatty acid transmembrane transporter activity	1/2658	19/18639	0.0526315789473684	0.369074492099323	0.946323726473861	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/2658	19/18639	0.0526315789473684	0.369074492099323	0.946323726473861	1
GO:0022821	solute:potassium antiporter activity	1/2658	19/18639	0.0526315789473684	0.369074492099323	0.946323726473861	1
GO:0022840	leak channel activity	1/2658	19/18639	0.0526315789473684	0.369074492099323	0.946323726473861	1
GO:0022842	narrow pore channel activity	1/2658	19/18639	0.0526315789473684	0.369074492099323	0.946323726473861	1
GO:0042834	peptidoglycan binding	1/2658	19/18639	0.0526315789473684	0.369074492099323	0.946323726473861	1
GO:0043395	heparan sulfate proteoglycan binding	1/2658	19/18639	0.0526315789473684	0.369074492099323	0.946323726473861	1
GO:0070003	threonine-type peptidase activity	1/2658	19/18639	0.0526315789473684	0.369074492099323	0.946323726473861	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/2658	31/18639	0.0645161290322581	0.452413893541105	0.947904585923846	1
GO:0005452	solute:inorganic anion antiporter activity	2/2658	31/18639	0.0645161290322581	0.452413893541105	0.947904585923846	1
GO:0017147	Wnt-protein binding	2/2658	31/18639	0.0645161290322581	0.452413893541105	0.947904585923846	1
GO:0070325	lipoprotein particle receptor binding	2/2658	31/18639	0.0645161290322581	0.452413893541105	0.947904585923846	1
GO:0072349	modified amino acid transmembrane transporter activity	2/2658	31/18639	0.0645161290322581	0.452413893541105	0.947904585923846	1
GO:0015291	secondary active transmembrane transporter activity	32/2658	287/18639	0.111498257839721	0.781872094760935	0.949437528678155	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	4/2658	52/18639	0.0769230769230769	0.539416565375933	0.950595168044669	1
GO:0001972	retinoic acid binding	1/2658	20/18639	0.05	0.350620767494357	0.95398600010611	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/2658	20/18639	0.05	0.350620767494357	0.95398600010611	1
GO:0010851	cyclase regulator activity	1/2658	20/18639	0.05	0.350620767494357	0.95398600010611	1
GO:0008378	galactosyltransferase activity	2/2658	32/18639	0.0625	0.438275959367946	0.954136738444615	1
GO:0042910	xenobiotic transmembrane transporter activity	2/2658	32/18639	0.0625	0.438275959367946	0.954136738444615	1
GO:0005518	collagen binding	6/2658	72/18639	0.0833333333333333	0.584367945823928	0.955072589325431	1
GO:0005544	calcium-dependent phospholipid binding	4/2658	53/18639	0.0754716981132075	0.529238894331104	0.955447760563876	1
GO:0015078	proton transmembrane transporter activity	19/2658	185/18639	0.102702702702703	0.720194008907327	0.957108139522449	1
GO:0072341	modified amino acid binding	8/2658	91/18639	0.0879120879120879	0.616476074715352	0.95777415973231	1
GO:0042923	neuropeptide binding	2/2658	33/18639	0.0606060606060606	0.424994869690129	0.959651641915701	1
GO:0022804	active transmembrane transporter activity	53/2658	457/18639	0.115973741794311	0.813256047142272	0.959905700892403	1
GO:0036122	BMP binding	1/2658	21/18639	0.0476190476190476	0.333924540470816	0.960554839018939	1
GO:0048029	monosaccharide binding	6/2658	74/18639	0.0810810810810811	0.568574217558416	0.962586120397671	1
GO:1902936	phosphatidylinositol bisphosphate binding	10/2658	111/18639	0.0900900900900901	0.631749130620462	0.964392281364687	1
GO:0015020	glucuronosyltransferase activity	2/2658	34/18639	0.0588235294117647	0.412495020581596	0.964527033996894	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	2/2658	34/18639	0.0588235294117647	0.412495020581596	0.964527033996894	1
GO:0042605	peptide antigen binding	3/2658	45/18639	0.0666666666666667	0.467494356659142	0.96484441802664	1
GO:0016758	hexosyltransferase activity	20/2658	197/18639	0.101522842639594	0.711920340090064	0.965650067698173	1
GO:0016881	acid-amino acid ligase activity	1/2658	22/18639	0.0454545454545455	0.318746152267597	0.966186230032348	1
GO:0033218	amide binding	26/2658	247/18639	0.105263157894737	0.738148984198646	0.9667813447163	1
GO:0030170	pyridoxal phosphate binding	4/2658	56/18639	0.0714285714285714	0.500886810706224	0.967487228151518	1
GO:0070279	vitamin B6 binding	4/2658	57/18639	0.0701754385964912	0.492099322799097	0.970773389461472	1
GO:0050840	extracellular matrix binding	5/2658	67/18639	0.0746268656716418	0.523314578349786	0.970847943340932	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/2658	23/18639	0.0434782608695652	0.304887623908136	0.971013914437678	1
GO:0005212	structural constituent of eye lens	1/2658	23/18639	0.0434782608695652	0.304887623908136	0.971013914437678	1
GO:0031681	G-protein beta-subunit binding	1/2658	23/18639	0.0434782608695652	0.304887623908136	0.971013914437678	1
GO:0140359	ABC-type transporter activity	3/2658	47/18639	0.0638297872340425	0.44760097978003	0.972118708293399	1
GO:0016409	palmitoyltransferase activity	2/2658	36/18639	0.0555555555555556	0.389578630549285	0.972632934151655	1
GO:0008237	metallopeptidase activity	18/2658	184/18639	0.0978260869565217	0.685997153793307	0.972874479435251	1
GO:0003777	microtubule motor activity	5/2658	68/18639	0.0735294117647059	0.515618775726995	0.973627345090599	1
GO:0004252	serine-type endopeptidase activity	17/2658	176/18639	0.0965909090909091	0.677335573568643	0.97374314988146	1
GO:0004806	triacylglycerol lipase activity	1/2658	24/18639	0.0416666666666667	0.292183972911964	0.975152559443299	1
GO:0005540	hyaluronic acid binding	1/2658	24/18639	0.0416666666666667	0.292183972911964	0.975152559443299	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/2658	24/18639	0.0416666666666667	0.292183972911964	0.975152559443299	1
GO:0030215	semaphorin receptor binding	1/2658	24/18639	0.0416666666666667	0.292183972911964	0.975152559443299	1
GO:0038187	pattern recognition receptor activity	3/2658	48/18639	0.0625	0.438275959367946	0.975196711671742	1
GO:0022829	wide pore channel activity	2/2658	37/18639	0.0540540540540541	0.379049478372277	0.975983342919168	1
GO:0042805	actinin binding	2/2658	37/18639	0.0540540540540541	0.379049478372277	0.975983342919168	1
GO:0005251	delayed rectifier potassium channel activity	1/2658	25/18639	0.04	0.280496613995485	0.978700477627544	1
GO:0015271	outward rectifier potassium channel activity	1/2658	25/18639	0.04	0.280496613995485	0.978700477627544	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/2658	25/18639	0.04	0.280496613995485	0.978700477627544	1
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/2658	25/18639	0.04	0.280496613995485	0.978700477627544	1
GO:0019707	protein-cysteine S-acyltransferase activity	1/2658	25/18639	0.04	0.280496613995485	0.978700477627544	1
GO:0005109	frizzled binding	2/2658	38/18639	0.0526315789473684	0.369074492099323	0.978935157947495	1
GO:0019838	growth factor binding	12/2658	136/18639	0.0882352941176471	0.618742530872394	0.979587573317747	1
GO:0048020	CCR chemokine receptor binding	3/2658	50/18639	0.06	0.420744920993228	0.980410223988423	1
GO:0005227	calcium-activated cation channel activity	1/2658	26/18639	0.0384615384615385	0.269708282687967	0.981741958795804	1
GO:0008198	ferrous iron binding	1/2658	26/18639	0.0384615384615385	0.269708282687967	0.981741958795804	1
GO:0030247	polysaccharide binding	1/2658	26/18639	0.0384615384615385	0.269708282687967	0.981741958795804	1
GO:0097602	cullin family protein binding	1/2658	26/18639	0.0384615384615385	0.269708282687967	0.981741958795804	1
GO:0005010	insulin-like growth factor receptor activity	3/2658	51/18639	0.0588235294117647	0.412495020581596	0.982607059400387	1
GO:0016298	lipase activity	11/2658	130/18639	0.0846153846153846	0.593358221913527	0.983900082909925	1
GO:0005044	scavenger receptor activity	1/2658	27/18639	0.037037037037037	0.259719087032857	0.984349269466881	1
GO:0008395	steroid hydroxylase activity	1/2658	27/18639	0.037037037037037	0.259719087032857	0.984349269466881	1
GO:0061135	endopeptidase regulator activity	17/2658	184/18639	0.0923913043478261	0.647886200804789	0.98474945070959	1
GO:0017046	peptide hormone binding	3/2658	53/18639	0.0566037735849057	0.396929170748328	0.986314123749173	1
GO:0045499	chemorepellent activity	1/2658	28/18639	0.0357142857142857	0.250443405353112	0.986584367347658	1
GO:0051393	alpha-actinin binding	1/2658	28/18639	0.0357142857142857	0.250443405353112	0.986584367347658	1
GO:0031406	carboxylic acid binding	17/2658	187/18639	0.0909090909090909	0.637492304535194	0.987650481272398	1
GO:0046943	carboxylic acid transmembrane transporter activity	17/2658	188/18639	0.0904255319148936	0.634101388021709	0.988498985296647	1
GO:0016417	S-acyltransferase activity	1/2658	29/18639	0.0344827586206897	0.241807425858177	0.988500371409231	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/2658	43/18639	0.0465116279069767	0.326158853483122	0.989146932539662	1
GO:0005342	organic acid transmembrane transporter activity	17/2658	189/18639	0.0899470899470899	0.630746354222652	0.989293670761857	1
GO:0043177	organic acid binding	17/2658	189/18639	0.0899470899470899	0.630746354222652	0.989293670761857	1
GO:0022839	monoatomic ion-gated channel activity	1/2658	30/18639	0.0333333333333333	0.233747178329571	0.990142822392265	1
GO:0170055	lipid transmembrane transporter activity	3/2658	56/18639	0.0535714285714286	0.375665108029668	0.990487881870109	1
GO:0019199	transmembrane receptor protein kinase activity	5/2658	78/18639	0.0641025641025641	0.449513804479944	0.990661278457752	1
GO:0016829	lyase activity	18/2658	200/18639	0.09	0.631117381489842	0.990852981382292	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/2658	32/18639	0.03125	0.219137979683973	0.992757667645403	1
GO:0005262	calcium channel activity	10/2658	131/18639	0.0763358778625954	0.535298881670774	0.993281836179056	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	9/2658	122/18639	0.0737704918032787	0.517309329090034	0.993645697596845	1
GO:0140299	molecular sensor activity	4/2658	71/18639	0.0563380281690141	0.395065653514768	0.993860201805308	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	3/2658	60/18639	0.05	0.350620767494357	0.994185914547089	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	2/2658	48/18639	0.0416666666666667	0.292183972911964	0.994467689344841	1
GO:0042379	chemokine receptor binding	4/2658	72/18639	0.0555555555555556	0.389578630549285	0.994530970238712	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/2658	34/18639	0.0294117647058824	0.206247510290798	0.994679055099534	1
GO:0019825	oxygen binding	1/2658	34/18639	0.0294117647058824	0.206247510290798	0.994679055099534	1
GO:0008514	organic anion transmembrane transporter activity	25/2658	269/18639	0.0929368029739777	0.651711463744157	0.994719992293182	1
GO:0005004	GPI-linked ephrin receptor activity	2/2658	49/18639	0.0408163265306122	0.286221034689271	0.995170575846136	1
GO:0005008	hepatocyte growth factor receptor activity	2/2658	49/18639	0.0408163265306122	0.286221034689271	0.995170575846136	1
GO:0005009	insulin receptor activity	2/2658	49/18639	0.0408163265306122	0.286221034689271	0.995170575846136	1
GO:0005011	macrophage colony-stimulating factor receptor activity	2/2658	49/18639	0.0408163265306122	0.286221034689271	0.995170575846136	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	2/2658	49/18639	0.0408163265306122	0.286221034689271	0.995170575846136	1
GO:0005020	stem cell factor receptor activity	2/2658	49/18639	0.0408163265306122	0.286221034689271	0.995170575846136	1
GO:0008288	boss receptor activity	2/2658	49/18639	0.0408163265306122	0.286221034689271	0.995170575846136	1
GO:0036332	placental growth factor receptor activity	2/2658	49/18639	0.0408163265306122	0.286221034689271	0.995170575846136	1
GO:0038062	protein tyrosine kinase collagen receptor activity	2/2658	49/18639	0.0408163265306122	0.286221034689271	0.995170575846136	1
GO:0060175	brain-derived neurotrophic factor receptor activity	2/2658	49/18639	0.0408163265306122	0.286221034689271	0.995170575846136	1
GO:0001664	G protein-coupled receptor binding	28/2658	297/18639	0.0942760942760943	0.66110313062909	0.995418927660015	1
GO:0016229	steroid dehydrogenase activity	1/2658	35/18639	0.0285714285714286	0.200354724282489	0.995439230941804	1
GO:0015081	sodium ion transmembrane transporter activity	13/2658	164/18639	0.0792682926829268	0.555862192369102	0.995512743958151	1
GO:0005006	epidermal growth factor receptor activity	2/2658	50/18639	0.04	0.280496613995485	0.995785590506874	1
GO:0005007	fibroblast growth factor receptor activity	2/2658	50/18639	0.04	0.280496613995485	0.995785590506874	1
GO:0005017	platelet-derived growth factor receptor activity	2/2658	50/18639	0.04	0.280496613995485	0.995785590506874	1
GO:0005019	platelet-derived growth factor beta-receptor activity	2/2658	50/18639	0.04	0.280496613995485	0.995785590506874	1
GO:1901682	sulfur compound transmembrane transporter activity	3/2658	63/18639	0.0476190476190476	0.333924540470816	0.996000490241077	1
GO:0005021	vascular endothelial growth factor receptor activity	2/2658	51/18639	0.0392156862745098	0.274996680387731	0.99632348973571	1
GO:0005030	neurotrophin receptor activity	2/2658	51/18639	0.0392156862745098	0.274996680387731	0.99632348973571	1
GO:0008509	monoatomic anion transmembrane transporter activity	11/2658	149/18639	0.0738255033557047	0.517695092944688	0.996822359095168	1
GO:0019842	vitamin binding	11/2658	150/18639	0.0733333333333333	0.514243792325056	0.997095510421707	1
GO:0005501	retinoid binding	1/2658	38/18639	0.0263157894736842	0.184537246049661	0.997128143775993	1
GO:0019840	isoprenoid binding	1/2658	38/18639	0.0263157894736842	0.184537246049661	0.997128143775993	1
GO:0005003	ephrin receptor activity	2/2658	53/18639	0.0377358490566038	0.264619447165552	0.997204716234666	1
GO:0005005	transmembrane-ephrin receptor activity	2/2658	53/18639	0.0377358490566038	0.264619447165552	0.997204716234666	1
GO:0016860	intramolecular oxidoreductase activity	2/2658	53/18639	0.0377358490566038	0.264619447165552	0.997204716234666	1
GO:0038064	collagen receptor activity	2/2658	53/18639	0.0377358490566038	0.264619447165552	0.997204716234666	1
GO:0030246	carbohydrate binding	25/2658	280/18639	0.0892857142857143	0.62610851338278	0.997495902564553	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	9/2658	132/18639	0.0681818181818182	0.478119228401395	0.997520919069894	1
GO:0052689	carboxylic ester hydrolase activity	5/2658	92/18639	0.0543478260869565	0.38110952988517	0.99800862611897	1
GO:0008227	G protein-coupled amine receptor activity	1/2658	41/18639	0.024390243902439	0.171034520728954	0.99819177580947	1
GO:0003735	structural constituent of ribosome	13/2658	175/18639	0.0742857142857143	0.520922283134473	0.998251484438511	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	3/2658	70/18639	0.0428571428571429	0.300532086423734	0.998353071079116	1
GO:0042562	hormone binding	5/2658	94/18639	0.0531914893617021	0.373000816483358	0.99841467339736	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/2658	44/18639	0.0227272727272727	0.159373076133798	0.998861568738107	1
GO:0004866	endopeptidase inhibitor activity	11/2658	161/18639	0.0683229813664596	0.479109123284214	0.998947232107413	1
GO:0008009	chemokine activity	1/2658	45/18639	0.0222222222222222	0.155831452219714	0.999024297982211	1
GO:0016836	hydro-lyase activity	2/2658	61/18639	0.0327868852459016	0.229915257373349	0.999076265988049	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/2658	46/18639	0.0217391304347826	0.152443811954068	0.999163773940223	1
GO:0008188	neuropeptide receptor activity	1/2658	48/18639	0.0208333333333333	0.146091986455982	0.999385778522699	1
GO:0046873	metal ion transmembrane transporter activity	42/2658	450/18639	0.0933333333333333	0.654492099322799	0.999432158394807	1
GO:0005253	monoatomic anion channel activity	5/2658	103/18639	0.0485436893203883	0.340408512130443	0.999442605675037	1
GO:0016835	carbon-oxygen lyase activity	3/2658	79/18639	0.0379746835443038	0.266294253793182	0.999486705188189	1
GO:0030414	peptidase inhibitor activity	11/2658	169/18639	0.0650887573964497	0.456429401471944	0.999510604053151	1
GO:0015079	potassium ion transmembrane transporter activity	10/2658	160/18639	0.0625	0.438275959367946	0.999568648654253	1
GO:0016500	protein-hormone receptor activity	2/2658	67/18639	0.0298507462686567	0.209325831339914	0.999601382148133	1
GO:0003823	antigen binding	11/2658	174/18639	0.0632183908045977	0.443313614073325	0.999700093944504	1
GO:0098632	cell-cell adhesion mediator activity	1/2658	55/18639	0.0181818181818182	0.127498460907039	0.999791451641506	1
GO:0005267	potassium channel activity	6/2658	124/18639	0.0483870967741935	0.339310420155829	0.999812550555571	1
GO:0098631	cell adhesion mediator activity	2/2658	76/18639	0.0263157894736842	0.184537246049661	0.999888460413681	1
GO:0005506	iron ion binding	8/2658	154/18639	0.051948051948052	0.364281316877254	0.999916529804475	1
GO:0004222	metalloendopeptidase activity	4/2658	110/18639	0.0363636363636364	0.254996921814078	0.999949219339497	1
GO:0005249	voltage-gated potassium channel activity	3/2658	98/18639	0.0306122448979592	0.214665776016953	0.999959202858031	1
GO:0008201	heparin binding	9/2658	172/18639	0.0523255813953488	0.366928710168513	0.999960504644893	1
GO:0046906	tetrapyrrole binding	7/2658	152/18639	0.0460526315789474	0.322940180586907	0.999971736230696	1
GO:0015103	inorganic anion transmembrane transporter activity	8/2658	165/18639	0.0484848484848485	0.339995895752103	0.999975718112656	1
GO:0020037	heme binding	6/2658	142/18639	0.0422535211267606	0.296299240136076	0.999977814517548	1
GO:1901681	sulfur compound binding	18/2658	275/18639	0.0654545454545455	0.45899445926534	0.999982672148833	1
GO:0005125	cytokine activity	14/2658	234/18639	0.0598290598290598	0.419546217514615	0.999982873839128	1
GO:0004497	monooxygenase activity	3/2658	106/18639	0.0283018867924528	0.198464585374164	0.999986266600811	1
GO:0015108	chloride transmembrane transporter activity	4/2658	121/18639	0.0330578512396694	0.231815383467343	0.999987839705637	1
GO:0008083	growth factor activity	7/2658	162/18639	0.0432098765432099	0.303005601538333	0.999991301853117	1
GO:0005539	glycosaminoglycan binding	14/2658	242/18639	0.0578512396694215	0.405676921067851	0.999992379085611	1
GO:0030527	structural constituent of chromatin	2/2658	98/18639	0.0204081632653061	0.143110517344635	0.999995281434163	1
GO:0005254	chloride channel activity	1/2658	83/18639	0.0120481927710843	0.084486931926351	0.999997240557752	1
GO:0005244	voltage-gated monoatomic ion channel activity	7/2658	173/18639	0.0404624277456647	0.283739349417398	0.999997680855363	1
GO:0022832	voltage-gated channel activity	7/2658	175/18639	0.04	0.280496613995485	0.999998181149118	1
GO:0099094	ligand-gated monoatomic cation channel activity	4/2658	136/18639	0.0294117647058824	0.206247510290798	0.999998331953323	1
GO:0008528	G protein-coupled peptide receptor activity	3/2658	122/18639	0.0245901639344262	0.172436443030011	0.999998491369165	1
GO:0001653	peptide receptor activity	3/2658	128/18639	0.0234375	0.16435348476298	0.999999346985271	1
GO:0022843	voltage-gated monoatomic cation channel activity	4/2658	143/18639	0.027972027972028	0.196151478318521	0.999999348207093	1
GO:0004867	serine-type endopeptidase inhibitor activity	1/2658	95/18639	0.0105263157894737	0.0738148984198645	0.99999956861953	1
GO:0005179	hormone activity	3/2658	132/18639	0.0227272727272727	0.159373076133798	0.999999627242514	1
GO:0005261	monoatomic cation channel activity	19/2658	341/18639	0.0557184750733138	0.390721089876409	0.999999928232507	1
GO:0015276	ligand-gated monoatomic ion channel activity	5/2658	186/18639	0.0268817204301075	0.188505788975461	0.999999985892738	1
GO:0022834	ligand-gated channel activity	5/2658	188/18639	0.0265957446808511	0.186500408241679	0.999999989219484	1
GO:0005216	monoatomic ion channel activity	27/2658	448/18639	0.0602678571428571	0.422623246533376	0.999999992585643	1
GO:0022836	gated channel activity	14/2658	318/18639	0.0440251572327044	0.308722688359811	0.999999998111896	1
GO:0005201	extracellular matrix structural constituent	1/2658	168/18639	0.00595238095238095	0.041740567558852	0.999999999994755	1
GO:0030371	translation repressor activity	2/2658	329/18639	0.0060790273556231	0.0426286647409552	1	1
GO:0045182	translation regulator activity	7/2658	356/18639	0.0196629213483146	0.137884571486545	1	1