category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	16/165	82/9376	11.0876570583888	HLA-DRA/HSPA1A/CTSL/HLA-B/CTSB/HLA-A/HLA-DPA1/B2M/LGMN/HSPA1B/HLA-C/HLA-DPB1/IFI30/HLA-E/HLA-DRB1/HLA-G	12.279201347615
Human Diseases	Immune disease	hsa05330	Allograft rejection	9/165	39/9376	13.1132867132867	HLA-DRA/HLA-B/HLA-A/HLA-DPA1/HLA-C/HLA-DPB1/HLA-E/HLA-DRB1/HLA-G	10.1452987447979
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	10/165	54/9376	10.5230078563412	HLA-DRA/CGA/HLA-B/HLA-A/HLA-DPA1/HLA-C/HLA-DPB1/HLA-E/HLA-DRB1/HLA-G	9.39270521355296
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	9/165	44/9376	11.6231404958678	HLA-DRA/HLA-B/HLA-A/HLA-DPA1/HLA-C/HLA-DPB1/HLA-E/HLA-DRB1/HLA-G	9.4529229409814
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	9/165	45/9376	11.3648484848485	HLA-DRA/HLA-B/HLA-A/HLA-DPA1/HLA-C/HLA-DPB1/HLA-E/HLA-DRB1/HLA-G	9.32780243838005
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	16/165	205/9376	4.43506282335551	HLA-DRA/HLA-B/HLA-A/HLA-DPA1/B2M/HLA-C/JUN/HLA-DPB1/SNW1/PSMD4/PSMC5/PSMD7/HLA-E/HLA-DRB1/PSMD6/HLA-G	6.65545095150049
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	18/165	275/9376	3.71940495867769	HSPA1A/C1QA/C1QB/HSPA1B/PSMD4/PSMC5/PSMD7/NDUFB8/MT-ND1/C1QC/NDUFB10/NDUFS8/PSMD6/BAD/EIF2S1/COX7B/NDUFAB1/UQCRFS1	6.12589987252929
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	16/165	224/9376	4.05887445887446	HLA-DRA/HLA-B/HLA-A/HLA-DPA1/B2M/HLA-C/JUN/HLA-DPB1/FOS/MAP2K2/SMAD2/HLA-E/HLA-DRB1/TLN1/ANAPC5/HLA-G	6.20157322230688
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	13/165	155/9376	4.76590420332356	HLA-DRA/CTSL/HLA-B/FCGR2B/HLA-A/HLA-DPA1/CD14/HLA-C/HLA-DPB1/HLA-E/HLA-DRB1/DYNC1LI1/HLA-G	6.32732766840248
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	9/165	70/9376	7.30597402597403	HLA-DRA/HLA-B/HLA-A/HLA-DPA1/HLA-C/HLA-DPB1/HLA-E/HLA-DRB1/HLA-G	7.08751339411126
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	13/165	160/9376	4.6169696969697	HLA-DRA/HLA-B/HLA-A/HLA-DPA1/HLA-C/HLA-DPB1/JAM2/PECAM1/HLA-E/HLA-DRB1/ESAM/JAM3/HLA-G	6.17600796884267
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	10/165	95/9376	5.98149920255183	CCL3/FLT1/HLA-DRA/CTSL/HLA-DPA1/CCL3L1/JUN/HLA-DPB1/FOS/HLA-DRB1	6.53128598489484
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	10/165	103/9376	5.51691674021771	CCL3/SERPINE1/C1QA/CCL3L1/C1QB/JUN/FOS/SMAD2/C1QC/PPP2R2A	6.16914228546464
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	15/165	268/9376	3.18046132971506	UBC/PSMD4/PSMC5/PSMD7/NDUFB8/MT-ND1/UBE2L3/NDUFB10/NDUFS8/PSMD6/EIF2S1/COX7B/NDUFAB1/UQCRFS1/SLC39A10	4.84706109790594
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	12/165	180/9376	3.78828282828283	HLA-DRA/HLA-B/HLA-A/HLA-DPA1/B2M/HLA-C/HLA-DPB1/HLA-E/HLA-DRB1/BAD/EIF2S1/HLA-G	5.05531025774183
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	9/165	109/9376	4.69190992493745	SPP1/CCL4/CCL3/CCL4L2/CCL3L1/CD14/JUN/FOS/MAP2K2	5.18882451509466
Human Diseases	Immune disease	hsa05310	Asthma	5/165	32/9376	8.87878787878788	PRG2/HLA-DRA/HLA-DPA1/HLA-DPB1/HLA-DRB1	5.97505904806681
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	8/165	99/9376	4.59185797367616	HLA-DRA/C1QA/FCGR2B/HLA-DPA1/C1QB/HLA-DPB1/C1QC/HLA-DRB1	4.80847313489673
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	10/165	157/9376	3.61937849835939	JUN/FOS/NDUFB8/IRS2/NDUFB10/NDUFS8/EIF2S1/COX7B/NDUFAB1/UQCRFS1	4.42976202838617
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	13/165	250/9376	2.95486060606061	HSPA1A/HLA-B/HLA-A/HSPA1B/HLA-C/CYTH1/SMAD2/WWP1/CAPZA1/HLA-E/VPS35/HLA-G/USP8	4.19295099049735
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	17/165	388/9376	2.48972196188691	APOE/PSMD4/PSMC5/MAP2K2/PSMD7/NDUFB8/MT-ND1/IRS2/NDUFB10/NDUFS8/PSMD6/BAD/EIF2S1/COX7B/NDUFAB1/UQCRFS1/SLC39A10	4.01110259479455
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	12/165	227/9376	3.00392470965158	CCL4/CCL3/CCL4L2/HLA-B/HLA-A/B2M/CCL3L1/HLA-C/MAP2K2/GNG11/HLA-E/HLA-G	4.09055027168469
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	16/165	368/9376	2.47061923583663	PSMD4/PSMC5/PSMD7/NDUFB8/MT-ND1/RANBP2/ANXA11/NDUFB10/NDUFS8/DERL1/PSMD6/BAD/EIF2S1/COX7B/NDUFAB1/UQCRFS1	3.85198140564364
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	6/165	66/9376	5.16584022038568	HLA-DRA/HLA-DPA1/JUN/HLA-DPB1/SMAD2/HLA-DRB1	4.54541933642126
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	11/165	214/9376	2.9208722741433	HLA-B/HLA-A/B2M/HLA-C/JUN/FOS/MAP2K2/GNG11/HLA-E/BAD/HLA-G	3.80438490743872
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	9/165	157/9376	3.25744064852345	SERPINE1/HLA-B/HLA-A/HLA-C/MAP2K2/SMAD2/HIPK1/HLA-E/HLA-G	3.81767082245958
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	7/165	101/9376	3.93831383138314	FN1/SERPINE1/COL4A1/COL4A2/JUN/SMAD2/VEGFC	3.97352661554968
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	8/165	130/9376	3.49687645687646	COL4A1/COL4A2/JUN/FOS/MAP2K2/SMAD2/GNG11/VEGFC	3.83677211589025
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	11/165	227/9376	2.75359765051395	JUN/FOS/MAP2K2/NDUFB8/MT-ND1/NDUFB10/NDUFS8/BAD/COX7B/NDUFAB1/UQCRFS1	3.57956529563561
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	10/165	196/9376	2.89919604205319	HLA-B/HLA-A/HLA-C/JUN/UBC/FOS/MAP2K2/GNG11/HLA-E/HLA-G	3.596256921578
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	6/165	78/9376	4.37109557109557	C1QA/CD14/C1QB/JUN/FOS/C1QC	4.0012696005949
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	6/165	78/9376	4.37109557109557	HLA-DRA/HLA-DPA1/JUN/HLA-DPB1/FOS/HLA-DRB1	4.0012696005949
Human Diseases	Infectious disease: viral	hsa05162	Measles	8/165	136/9376	3.34260249554367	HSPA1A/FCGR2B/HSPA1B/JUN/FOS/MSN/BAD/EIF2S1	3.68303875974158
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	9/165	169/9376	3.02614308768155	CTSL/CTSB/UBC/MAP2K2/IGBP1/IRS2/BAD/EIF2S1/DAPK1	3.55736650998671
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	8/165	138/9376	3.2941589811155	NDUFB8/MT-ND1/PPA1/NDUFB10/NDUFS8/COX7B/NDUFAB1/UQCRFS1	3.63369351520624
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	7/165	109/9376	3.64926327495135	HLA-DRA/HLA-DPA1/JUN/HLA-DPB1/FOS/SMAD2/HLA-DRB1	3.72342839004677
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	7/165	112/9376	3.55151515151515	HLA-DRA/HSPA1A/HLA-DPA1/HSPA1B/HLA-DPB1/HLA-DRB1/BAD	3.6356503466317
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	6/165	87/9376	3.91891327063741	JUN/FOS/MAP2K2/SMAD2/APPL1/BAD	3.66075407981479
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	6/165	88/9376	3.87438016528926	SERPINE1/F13A1/SERPINE2/C1QA/C1QB/C1QC	3.62575670869857
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	17/165	480/9376	2.01252525252525	UBC/PSMD4/PSMC5/MAP2K2/PSMD7/NDUFB8/MT-ND1/UBE2L3/NDUFB10/NDUFS8/DERL1/PSMD6/BAD/EIF2S1/COX7B/NDUFAB1/UQCRFS1	3.04791824828072
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	14/165	362/9376	2.1976226351917	SPP1/FN1/FLT1/CSH1/COL4A1/COL4A2/MAP2K2/PPP2R5E/GNG11/PPP2R2A/EIF4B/BAD/VEGFC/EIF4E2	3.11021007010773
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	13/165	333/9376	2.21836381836382	SPP1/FN1/COL4A1/HLA-B/HLA-A/HLA-C/COL4A2/MAP2K2/PPP2R5E/HLA-E/PPP2R2A/BAD/HLA-G	3.02982164462557
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	6/165	93/9376	3.66608015640274	HLA-DRA/HLA-DPA1/JUN/HLA-DPB1/FOS/HLA-DRB1	3.4581571142137
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	12/165	308/9376	2.21393152302243	PSMD4/PSMC5/PSMD7/NDUFB8/MT-ND1/NDUFB10/NDUFS8/PSMD6/COX7B/NDUFAB1/POLR2F/UQCRFS1	2.89926565501589
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	4/165	46/9376	4.94123847167325	PSMD4/PSMC5/PSMD7/PSMD6	3.58628687299173
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	7/165	133/9376	2.99074960127592	HLA-B/HLA-A/HLA-C/MAP2K2/HLA-E/LCP2/HLA-G	3.09464046880543
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	10/165	238/9376	2.38757321110262	F13A1/C1QA/C1QB/JUN/FOS/RPS18/RPS17/RPS4Y1/C1QC/RPL7A	2.90197072823285
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	9/165	203/9376	2.51930138826691	SPP1/FN1/FLT1/COL4A1/COL4A2/JUN/BAD/TLN1/VEGFC	2.92894000595843
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	7/165	137/9376	2.90342844503428	CTSL/CTSB/JUN/FOS/MAP2K2/BAD/EIF2S1	3.00371396950873
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	4/165	50/9376	4.54593939393939	AOC1/SAT1/P4HA1/SAT2	3.3646726987582
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	4/165	50/9376	4.54593939393939	HLA-DRA/HLA-DPA1/HLA-DPB1/HLA-DRB1	3.3646726987582
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	6/165	110/9376	3.0995041322314	FLT1/SERPINE1/EPAS1/LDHA/MAP2K2/EIF4E2	2.96442964422635
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	7/165	143/9376	2.78160627251536	HLA-DRA/C1QA/HLA-DPA1/C1QB/HLA-DPB1/C1QC/HLA-DRB1	2.8733104553318
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	9/165	216/9376	2.36767676767677	CCL3/HSPA1A/CCL3L1/CD14/HSPA1B/JUN/FOS/BAD/EIF2S1	2.72167853172417
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	4/165	56/9376	4.05887445887446	HSPA1A/CD14/HSPA1B/SAR1B	3.07271251788241
NA	NA	hsa04518	Integrin signaling	7/165	154/9376	2.58292011019284	SPP1/FN1/FLT1/COL4A1/COL4A2/TLN1/VEGFC	2.6508247526163
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	6/165	122/9376	2.7946348733234	JUN/FOS/MAP2K2/PPP2R5E/PPP2R2A/LCP2	2.67033341077949
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	7/165	157/9376	2.53356494885157	C1QA/STAB1/C1QB/MAP2K2/PECAM1/C1QC/UQCRFS1	2.5934884106064
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	8/165	204/9376	2.22840166369578	FN1/TIMP3/CTSL/MAP2K2/SMAD2/MSN/EIF4B/HCLS1	2.37409271734732
Genetic Information Processing	Transcription	hsa03040	Spliceosome	9/165	243/9376	2.10460157126824	HSPA1A/HSPA1B/SF3B5/BUD31/SNW1/RBM25/LSM7/SNRPE/SNRPA1	2.33494300343933
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	8/165	205/9376	2.21753141167775	HLA-B/HLA-A/HLA-C/JUN/SNW1/HLA-E/BAD/HLA-G	2.35897304038733
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	8/165	205/9376	2.21753141167775	NDUFB8/MT-ND1/SMAD2/NDUFB10/NDUFS8/COX7B/NDUFAB1/UQCRFS1	2.35897304038733
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	5/165	100/9376	2.84121212121212	HLA-DRA/HLA-DPA1/CD14/HLA-DPB1/HLA-DRB1	2.47740879182496
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	7/165	173/9376	2.29924680329305	HLA-DRA/HLA-DPA1/HLA-DPB1/MAP2K2/HLA-DRB1/EIF2S1/IL33	2.30846990247783
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	7/165	174/9376	2.28603274120516	HSPA1A/HSPA1B/SAR1B/DERL2/DERL1/EIF2S1/LMAN2	2.29171049854731
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	4/165	70/9376	3.24709956709957	EPAS1/JUN/MAP2K2/BAD	2.52559687276222
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	6/165	138/9376	2.47061923583663	FN1/JUN/FOS/MAP2K2/WASF2/LCP2	2.32929784927057
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	4/165	71/9376	3.20136577037986	JUN/JAM2/CSK/JAM3	2.49193903993547
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	6/165	140/9376	2.43532467532468	SPP1/SERPINE1/MAP2K2/SMAD2/GNG11/APLNR	2.2900577054714
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	3/165	42/9376	4.05887445887446	FTL/SAT1/SAT2	2.65905070735996
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	6/165	142/9376	2.40102432778489	UBC/UBE2L3/WWP1/UBA2/TRIP12/ANAPC5	2.25148538820236
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	7/165	181/9376	2.1976226351917	HLA-DRA/FCGR2B/HLA-DPA1/CD14/HLA-DPB1/HLA-DRB1/BAD	2.17749735139948
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	6/165	149/9376	2.2882245271507	NDUFB8/MT-ND1/GNG11/NDUFB10/NDUFS8/NDUFAB1	2.12142975874432
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	8/165	233/9376	1.95104695018858	FN1/FBLN1/COL4A1/COL4A2/SPTBN1/PDLIM5/CAPZA1/TLN1	1.96747751139653
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	5/165	116/9376	2.44932079414838	JAM2/PECAM1/MSN/ESAM/JAM3	2.10214294089287
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	4/165	83/9376	2.73851770719241	CCL4/CCL4L2/POLR2F/IL33	2.12918998729099
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	3/165	52/9376	3.27832167832168	APOE/APOC1/PLTP	2.20490458751955
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	4/165	89/9376	2.55389853592101	SPP1/FN1/COL4A1/COL4A2	1.97130651491569
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	4/165	91/9376	2.4977688977689	FCGR2B/JUN/FOS/MAP2K2	1.92153707869547
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	8/165	253/9376	1.79681398969937	CD14/CYTH1/JUN/UBE2V2/UBC/WASF2/TLN1/HCLS1	1.71958082126071
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	6/165	170/9376	2.0055614973262	JUN/JAM2/MSN/PPP2R2A/JAM3/HCLS1	1.77080944837211
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	4/165	94/9376	2.4180528691167	FOSB/JUN/FOS/ANAPC5	1.84931029268047
NA	NA	hsa04081	Hormone signaling	7/165	219/9376	1.816299986163	CSH1/CGA/RAMP2/DIO2/IRS2/GNG11/APPL1	1.63594786244922
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	3/165	62/9376	2.74956011730205	HSPA1A/HSPA1B/IRS2	1.84982573512561
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	4/165	99/9376	2.29592898683808	JUN/FOS/MAP2K2/BAD	1.73487920836891
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	4/165	99/9376	2.29592898683808	JUN/FOS/MAP2K2/WASF2	1.73487920836891
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	5/165	139/9376	2.04403749727491	HSPA1A/HSPA1B/JUN/FOS/MAP2K2	1.65971012875748
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	4/165	100/9376	2.2729696969697	CCL4/CCL3/CCL4L2/CCL3L1	1.71282074600038
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	2/165	31/9376	3.66608015640274	GET3/SRP72	1.9899337398919
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	5/165	142/9376	2.00085360648741	FCGR2B/FOSB/JUN/FOS/LCP2	1.60839981579678
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	3/165	65/9376	2.62265734265734	SPP1/CGA/MAP2K2	1.75695061144529
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	4/165	103/9376	2.20676669608708	PPP2R5E/PAPOLA/PPP2R2A/SSU72	1.64818522937008
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	4/165	103/9376	2.20676669608708	FN1/COL4A1/CD14/COL4A2	1.64818522937008
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	2/165	32/9376	3.55151515151515	LDHA/HADHA	1.9349998917201
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	5/165	144/9376	1.97306397306397	C1QA/CD14/C1QB/LPIN2/C1QC	1.57488541397508
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	5/165	144/9376	1.97306397306397	PSMD4/PSMC5/PSMD7/PUM1/PSMD6	1.57488541397508
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	4/165	105/9376	2.16473304473304	JUN/UBC/EIF2S1/USP8	1.60631966151656
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	3/165	68/9376	2.50695187165775	CD14/MAP2K2/BAD	1.6691673092504
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	7/165	235/9376	1.69263700838169	NDUFB8/MT-ND1/NDUFB10/NDUFS8/COX7B/NDUFAB1/UQCRFS1	1.43918620823466
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	3/165	69/9376	2.47061923583663	FOSB/JUN/FOS	1.64094547200538
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	6/165	193/9376	1.76655675930287	CCL4/CCL3/CCL4L2/CCL3L1/GNG11/BAD	1.44014061637444
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	3/165	71/9376	2.40102432778489	CGA/FOS/MAP2K2	1.5859550762907
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	3/165	71/9376	2.40102432778489	LDHA/MAP2K2/IDH2	1.5859550762907
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	6/165	200/9376	1.70472727272727	CYTH1/JUN/FOS/WASF2/MYO6/HCLS1	1.34829086917761
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	5/165	158/9376	1.79823551975451	CDKN1C/PPP2R5E/SMC1A/SMAD2/ANAPC5	1.35430181277196
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	7/165	248/9376	1.6039100684262	CD14/CYTH1/JUN/FOS/MAP2K2/DYNC1LI1/MYO6	1.28998456568904
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	4/165	117/9376	1.94270914270914	MEAF6/BAZ1B/EPC2/MORF4L2	1.37329180045984
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	3/165	77/9376	2.21393152302243	SMAD2/RALBP1/BAD	1.43151415613991
NA	NA	hsa04517	IgSF CAM signaling	8/165	299/9376	1.52038106820716	MAP2K2/JAM2/SPTBN1/MSN/CSK/ESAM/JAM3/LCP2	1.22394001555792
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	3/165	78/9376	2.18554778554779	FN1/WASF2/HCLS1	1.40716755556808
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	8/165	300/9376	1.51531313131313	FLT1/HSPA1A/CD14/HSPA1B/JUN/FOS/MAP2K2/VEGFC	1.21411216967041
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	2/165	41/9376	2.77191426459719	MAP2K2/DAPK1	1.52177936465616
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	3/165	80/9376	2.13090909090909	MAP2K2/BAD/EIF4E2	1.35956147674124
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	4/165	122/9376	1.86308991554893	CSH1/FOS/MAP2K2/IRS2	1.28423774231531
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	2/165	42/9376	2.70591630591631	AOC1/HADHA	1.4829369498259
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	6/165	212/9376	1.6082332761578	FLT1/ID1/MAP2K2/LCP2/TLN1/VEGFC	1.19886363189966
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	4/165	125/9376	1.81837575757576	MAP2K2/PPP2R5E/ORMDL1/PPP2R2A	1.23278585074648
Genetic Information Processing	Information processing in viruses	hsa03265	Virion - Ebolavirus, Lyssavirus and Morbillivirus	1/165	12/9376	4.73535353535353	FCGR2B	1.73286947630704
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	3/165	86/9376	1.98224101479915	JUN/MAP2K2/BAD	1.22471109570681
Genetic Information Processing	Translation	hsa03010	Ribosome	6/165	222/9376	1.53579033579034	RPS18/RPS17/RPS4Y1/DAP3/RPL7A/MRPS18C	1.08128487512905
Genetic Information Processing	Replication and repair	hsa03450	Non-homologous end-joining	1/165	13/9376	4.37109557109557	XRCC6	1.62783150155362
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	4/165	133/9376	1.70899977215767	FOS/PPP2R5E/GNG11/PPP2R2A	1.10214734484271
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	3/165	90/9376	1.89414141414141	IRS2/APPL1/EIF4E2	1.14074177176977
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/165	90/9376	1.89414141414141	JUN/FOS/MAP2K2	1.14074177176977
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	2/165	49/9376	2.31935683364255	FOSB/JUN	1.23926316618797
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	3/165	93/9376	1.83304007820137	CGA/JUN/MAP2K2	1.08053145586746
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	3/165	93/9376	1.83304007820137	FN1/COL4A1/COL4A2	1.08053145586746
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	4/165	138/9376	1.64707949055775	MAP2K2/IRS2/BAD/EIF4E2	1.02490218333491
Metabolism	Glycan biosynthesis and metabolism	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/165	15/9376	3.78828282828283	HEXB	1.44642376990297
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	4/165	142/9376	1.60068288518993	CTSL/JUN/FOS/PECAM1	0.965314243391213
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	6/165	238/9376	1.43254392666157	FLT1/MAP2K2/GNG11/RALBP1/BAD/VEGFC	0.904622403922979
Metabolism	Glycan biosynthesis and metabolism	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	1/165	16/9376	3.55151515151515	HEXB	1.36708159907478
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	4/165	144/9376	1.57845117845118	ID1/MAP2K2/KLF4/SMAD2	0.936212159587954
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	2/165	55/9376	2.06633608815427	PSAP/HEXB	1.06149613513633
Metabolism	Energy metabolism	hsa00910	Nitrogen metabolism	1/165	17/9376	3.34260249554367	GLUL	1.29384591148649
Metabolism	Glycan biosynthesis and metabolism	hsa00511	Other glycan degradation	1/165	18/9376	3.15690235690236	HEXB	1.22588416804999
Organismal Systems	Digestive system	hsa04980	Cobalamin transport and metabolism	1/165	18/9376	3.15690235690236	MMADHC	1.22588416804999
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	6/165	250/9376	1.36378181818182	PSAP/CTSL/CTSB/LGMN/HEXB/VPS35	0.780270127773547
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/165	59/9376	1.92624550590652	CGA/IRS2	0.955186753512486
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	2/165	59/9376	1.92624550590652	MAP2K2/BAD	0.955186753512486
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	3/165	105/9376	1.62354978354978	CCL4/CCL4L2/CD14	0.859956950461538
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	2/165	60/9376	1.89414141414141	MAP2K2/BAD	0.929910850165008
Metabolism	Glycan biosynthesis and metabolism	hsa00531	Glycosaminoglycan degradation	1/165	19/9376	2.99074960127592	HEXB	1.16251707981772
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	4/165	156/9376	1.45703185703186	MAP2K2/PPP2R2A/BAD/EIF2S1	0.770402229731051
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	4/165	157/9376	1.44775139934376	SERPINE1/ID1/SMAD2/PPP2R2A	0.757214792826633
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	4/165	158/9376	1.43858841580361	MAP2K2/LPIN2/EIF4B/EIF4E2	0.744117584201565
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	2/165	63/9376	1.8039442039442	PRDM2/HADHA	0.856891038438248
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	4/165	163/9376	1.39445993679123	JUN/FOS/MAP2K2/BAD	0.67993968007157
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/165	22/9376	2.58292011019284	AOC1	0.994823128120321
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	5/165	217/9376	1.30931434157241	JUN/FOS/MAP2K2/KLF4/BAD	0.616992824636064
Metabolism	Amino acid metabolism	hsa00220	Arginine biosynthesis	1/165	23/9376	2.47061923583663	GLUL	0.94506768244468
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	2/165	69/9376	1.64707949055775	MAP2K2/LCP2	0.722023848310555
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	3/165	119/9376	1.43254392666157	JUN/FOS/VEGFC	0.635539849017358
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	2/165	70/9376	1.62354978354978	IRS2/APPL1	0.700830264222607
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	3/165	120/9376	1.42060606060606	JUN/MAP2K2/BAD	0.620624184886942
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	3/165	122/9376	1.3973174366617	PPP2R5E/IRS2/PPP2R2A	0.591189908083219
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	3/165	122/9376	1.3973174366617	MAP2K2/DIO2/BAD	0.591189908083219
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	5/165	226/9376	1.25717350496112	CGA/JUN/FOS/MAP2K2/BAD	0.523774216050578
Human Diseases	Cancer: specific types	hsa05218	Melanoma	2/165	73/9376	1.55682855956829	MAP2K2/BAD	0.639213061639723
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	2/165	73/9376	1.55682855956829	MAP2K2/BAD	0.639213061639723
Metabolism	Carbohydrate metabolism	hsa00650	Butanoate metabolism	1/165	27/9376	2.10460157126824	HADHA	0.769270676389407
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	2/165	75/9376	1.51531313131313	GLUL/IDH2	0.599668502309406
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	2/165	75/9376	1.51531313131313	TOP2B/BAD	0.599668502309406
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	2/165	76/9376	1.49537480063796	PLTP/UBC	0.580327901677672
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/165	28/9376	2.02943722943723	HADHA	0.730119173253575
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	2/165	77/9376	1.47595434868162	MAP2K2/BAD	0.561263444347924
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	2/165	78/9376	1.45703185703186	CNOT4/LSM7	0.542466873892481
Metabolism	Carbohydrate metabolism	hsa00020	Citrate cycle (TCA cycle)	1/165	30/9376	1.89414141414141	IDH2	0.65649008125534
Metabolism	Metabolism of other amino acids	hsa00410	beta-Alanine metabolism	1/165	31/9376	1.83304007820137	HADHA	0.621772212779893
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/165	31/9376	1.83304007820137	GLUL	0.621772212779893
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	6/165	298/9376	1.14411226357535	CCL4/CCL3/CCL4L2/CSH1/CCL3L1/IL33	0.338367156452524
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	1/165	32/9376	1.77575757575758	IGBP1	0.588313506271194
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	3/165	138/9376	1.23530961791831	PPP2R5E/SMC1A/ANAPC5	0.372704350367071
Metabolism	Global and overview maps	hsa01210	2-Oxocarboxylic acid metabolism	1/165	33/9376	1.72194674012856	IDH2	0.556023534865307
Genetic Information Processing	Transcription	hsa03020	RNA polymerase	1/165	34/9376	1.67130124777184	POLR2F	0.524820995414026
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	2/165	87/9376	1.3063044235458	COX7B/UQCRFS1	0.384151588003762
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/165	89/9376	1.2769492679605	GLUL/GNG11	0.351343336524918
Metabolism	Carbohydrate metabolism	hsa00040	Pentose and glucuronate interconversions	1/165	36/9376	1.57845117845118	DCXR	0.465391815712078
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	1/165	37/9376	1.53579033579034	GLUL	0.437038572861752
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/165	37/9376	1.53579033579034	MAP2K2	0.437038572861752
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	3/165	148/9376	1.15184275184275	JUN/FOS/MAP2K2	0.249198457506764
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/165	38/9376	1.49537480063796	HEXB	0.409517997815627
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	3/165	154/9376	1.10696576151122	JUN/FOS/MAP2K2	0.179129373915049
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/165	97/9376	1.17163386441737	FOS/GNG11	0.227411529883337
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/165	98/9376	1.15967841682127	FCGR2B/WASF2	0.212670029313894
NA	NA	hsa04382	Cornified envelope formation	4/165	217/9376	1.04745147325792	COL4A1/COL4A2/PPP2R5E/PPP2R2A	0.094651991788413
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/165	43/9376	1.3214940098661	HADHA	0.282794331214685
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/165	44/9376	1.29146005509642	HEXB	0.259353572728549
Genetic Information Processing	Replication and repair	hsa03410	Base excision repair	1/165	44/9376	1.29146005509642	TDG	0.259353572728549
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/165	44/9376	1.29146005509642	DYNC1LI1	0.259353572728549
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	2/165	103/9376	1.10338334804354	COL4A1/COL4A2	0.141199544005229
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/165	46/9376	1.23530961791831	FTL	0.214117415095381
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	2/165	106/9376	1.07215551743854	MAP2K2/BAD	0.0999900602674359
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	3/165	166/9376	1.02694414019715	MAP2K2/IRS2/BAD	0.0468773202979244
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	1/165	47/9376	1.20902643455835	LDHA	0.192267913915071
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/165	47/9376	1.20902643455835	IRS2	0.192267913915071
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	3/165	168/9376	1.01471861471861	FTL/GLUL/IL33	0.0257639911828924
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	1/165	48/9376	1.18383838383838	HADHA	0.170897914322302
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	2/165	109/9376	1.0426466499861	OGA/IRS2	0.0599380774270335
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	3/165	170/9376	1.0027807486631	MAP2K2/SMAD2/BAD	0.00489694167811893
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/165	110/9376	1.03316804407713	ID1/SMAD2	0.0468321693650412
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/165	232/9376	0.979728317659352	FN1/MAP2K2/MSN/WASF2	-0.0418446457034391
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/165	50/9376	1.13648484848485	PECAM1	0.12950780948936
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/165	52/9376	1.09277389277389	CGA	0.0897843284052366
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	2/165	115/9376	0.988247694334651	FOS/GNG11	-0.0169713846117038
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	2/165	116/9376	0.979728317659352	GLUL/GNG11	-0.0294027202979968
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	3/165	178/9376	0.957711950970378	NOTUM/JUN/TBL1XR1	-0.07623513382537
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/165	54/9376	1.05230078563412	LDHA	0.0515851576843333
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/165	57/9376	0.996916533758639	HADHA	-0.00312511633636863
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/165	59/9376	0.963122752953261	IDH2	-0.0380295047699881
Organismal Systems	Immune system	hsa04611	Platelet activation	2/165	126/9376	0.901972101972102	LCP2/TLN1	-0.148264888625278
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/165	60/9376	0.947070707070707	MAP2K2	-0.0550466883739793
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/165	61/9376	0.931544957774466	FTL	-0.071788214158221
Cellular Processes	Cell motility	hsa04814	Motor proteins	3/165	194/9376	0.878725398313027	CAPZA1/DYNC1LI1/MYO6	-0.228442180459488
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/165	62/9376	0.916520039100684	SNW1	-0.0882641176554514
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/165	63/9376	0.901972101972102	PTGES	-0.104483901898836
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/165	63/9376	0.901972101972102	POLR2F	-0.104483901898836
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	2/165	133/9376	0.854499886078833	MAP2K2/IRS2	-0.226181404465762
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/165	65/9376	0.874219114219114	LPIN2	-0.136190678322111
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	2/165	134/9376	0.84812302125735	RAMP2/MAP2K2	-0.236993036513514
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/165	67/9376	0.84812302125735	LDHA	-0.166975231622729
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/165	67/9376	0.84812302125735	MAP2K2	-0.166975231622729
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/165	69/9376	0.823539745278876	CTSB	-0.196897775384268
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/165	73/9376	0.778414279784143	RANBP2	-0.254370010662952
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/165	75/9376	0.757656565656566	SERPINE1	-0.282014401509473
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/165	75/9376	0.757656565656566	CGA	-0.282014401509473
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/165	76/9376	0.747687400318979	MAP2K2	-0.295582337557655
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	2/165	149/9376	0.762741509050234	CYTH1/MAP2K2	-0.390713895448695
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	2/165	150/9376	0.757656565656566	MAP2K2/SMAD2	-0.400446388914072
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	2/165	154/9376	0.737977174340811	PPP2R5E/PPP2R2A	-0.438794470760263
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/165	155/9376	0.733216031280547	MAP2K2/USP8	-0.448240182337899
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/165	83/9376	0.684629426798102	IDH2	-0.386239302579267
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/165	89/9376	0.638474633980252	MAP2K2	-0.458638252670467
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/165	91/9376	0.624442224442224	GNG11	-0.48181544696357
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/165	93/9376	0.611013359400456	WASF2	-0.504552316363364
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/165	101/9376	0.562616261626163	MAP2K2	-0.591480701303768
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/165	104/9376	0.546386946386946	LPIN2	-0.622572195762404
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/165	187/9376	0.607745908280668	CTSB/JUN	-0.725150881428804
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/165	105/9376	0.541183261183261	JUN	-0.632768471648502
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/165	107/9376	0.531067686207873	LDHA	-0.652919782996287
Human Diseases	Substance dependence	hsa05034	Alcoholism	2/165	191/9376	0.595018245280025	FOSB/GNG11	-0.756809857652204
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/165	108/9376	0.526150392817059	RANBP2	-0.662878005568044
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/165	110/9376	0.516584022038567	ANAPC5	-0.682567199350286
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/165	115/9376	0.494123847167325	GNG11	-0.730530586940553
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/165	115/9376	0.494123847167325	FOS	-0.730530586940553
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/165	201/9376	0.5654153475049	FLT1/CD14	-0.8335729180681
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/165	116/9376	0.489864158829676	IDH2	-0.739917940694951
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	3/165	323/9376	0.527779341401632	TIMP3/MAP2K2/IRS2	-1.15591048385499
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/165	254/9376	0.447434979718444	FLT1/VEGFC	-1.19489414276804
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/165	168/9376	0.338239538239538	CSH1	-1.15836925063475
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	3/165	370/9376	0.460737100737101	CSH1/CGA/APLNR	-1.41647740803014
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/165	195/9376	0.291406371406371	MAP2K2	-1.33827009753623
NA	NA	hsa04082	Neuroactive ligand signaling	1/165	199/9376	0.285548956905741	GNG11	-1.36339867042607
NA	NA	hsa04519	Cadherin signaling	1/165	404/9376	0.140654065406541	MAP2K2	-2.36313371311742