ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0042605 peptide antigen binding 10/279 45/18639 0.222222222222222 14.8458781362007 9.6646841551833e-10 5.93411607128254e-07 GO:0023026 MHC class II protein complex binding 6/279 27/18639 0.222222222222222 14.8458781362007 2.42236497660173e-06 0.00074366604781673 GO:0042277 peptide binding 15/279 249/18639 0.0602409638554217 4.02448503692188 5.565179447854e-06 0.00113900672699412 GO:0042608 T cell receptor binding 4/279 11/18639 0.363636363636364 24.2932551319648 1.49261251700551e-05 0.00206038276312741 GO:0023023 MHC protein complex binding 6/279 37/18639 0.162162162162162 10.8334786399303 1.67783612632525e-05 0.00206038276312741 GO:0045296 cadherin binding 16/279 334/18639 0.0479041916167665 3.20030905930075 4.67381387283104e-05 0.00478286952986377 GO:0003712 transcription coregulator activity 19/279 495/18639 0.0383838383838384 2.5642880417074 0.000179630479554649 0.0157561592066506 GO:0043394 proteoglycan binding 5/279 37/18639 0.135135135135135 9.02789886660854 0.000213491075916512 0.0163854400765923 GO:0003823 antigen binding 10/279 174/18639 0.0574712643678161 3.83945124212088 0.000300593003810429 0.0205071227044004 GO:0043021 ribonucleoprotein complex binding 10/279 177/18639 0.0564971751412429 3.77437579733916 0.000344521289761875 0.0205590919197148 GO:0032395 MHC class II receptor activity 3/279 10/18639 0.3 20.041935483871 0.000368322493675673 0.0205590919197148 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 6/279 68/18639 0.0882352941176471 5.89468690702087 0.000536165944370129 0.0274338241536049 GO:0003743 translation initiation factor activity 5/279 51/18639 0.0980392156862745 6.54965211891208 0.000970234368800689 0.0434551051381162 GO:0035925 mRNA 3'-UTR AU-rich region binding 4/279 30/18639 0.133333333333333 8.90752688172043 0.000990833016178545 0.0434551051381162 GO:0071813 lipoprotein particle binding 4/279 32/18639 0.125 8.3508064516129 0.00127000233489049 0.0466385884445738 GO:0071814 protein-lipid complex binding 4/279 32/18639 0.125 8.3508064516129 0.00127000233489049 0.0466385884445738 GO:0033218 amide binding 11/279 247/18639 0.0445344129554656 2.97518610421836 0.0012912964227325 0.0466385884445738 GO:0008135 translation factor activity, RNA binding 6/279 83/18639 0.072289156626506 4.82938204430626 0.0015345667725236 0.0523457776849716 GO:0180051 translation factor activity 6/279 84/18639 0.0714285714285714 4.77188940092166 0.00163224904863496 0.0527474166243088 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 5/279 58/18639 0.0862068965517241 5.75917686318131 0.00173852566924165 0.0533727380457185 GO:0030169 low-density lipoprotein particle binding 3/279 17/18639 0.176470588235294 11.7893738140417 0.00193127317474763 0.0564667490140496 GO:0004197 cysteine-type endopeptidase activity 6/279 88/18639 0.0681818181818182 4.5549853372434 0.00207094641116495 0.0577982316570582 GO:0008137 NADH dehydrogenase (ubiquinone) activity 4/279 41/18639 0.0975609756097561 6.5177025963808 0.00321926290890724 0.0859403228725671 GO:0005201 extracellular matrix structural constituent 8/279 168/18639 0.0476190476190476 3.18125960061444 0.00386599041709237 0.0989049215039464 GO:0003954 NADH dehydrogenase activity 4/279 44/18639 0.0909090909090909 6.0733137829912 0.00416705366423683 0.0989677848171887 GO:0042393 histone binding 10/279 247/18639 0.0404858299595142 2.70471464019851 0.00419081824958779 0.0989677848171887 GO:0003725 double-stranded RNA binding 5/279 75/18639 0.0666666666666667 4.45376344086021 0.00533342289705723 0.121285987362709 GO:0031625 ubiquitin protein ligase binding 11/279 302/18639 0.0364238410596026 2.43334757530442 0.00600636343619571 0.131710969636577 GO:0070412 R-SMAD binding 3/279 26/18639 0.115384615384615 7.70843672456576 0.00668684930358877 0.139158566821472 GO:0043022 ribosome binding 6/279 112/18639 0.0535714285714286 3.57891705069124 0.00679927850919245 0.139158566821472 GO:0061134 peptidase regulator activity 9/279 226/18639 0.0398230088495575 2.66043391378818 0.00716655562474791 0.139799083992015 GO:0008234 cysteine-type peptidase activity 8/279 187/18639 0.0427807486631016 2.85803001552527 0.00728594574551218 0.139799083992015 GO:0009055 electron transfer activity 6/279 116/18639 0.0517241379310345 3.45550611790879 0.0080284786336667 0.147177013447089 GO:0001540 amyloid-beta binding 5/279 83/18639 0.0602409638554217 4.02448503692188 0.0081498671941385 0.147177013447089 GO:0022853 active monoatomic ion transmembrane transporter activity 6/279 118/18639 0.0508474576271186 3.39693821760525 0.00869959734903414 0.152615793494485 GO:0044389 ubiquitin-like protein ligase binding 11/279 322/18639 0.0341614906832298 2.28220797435384 0.00949345529951876 0.160050892739861 GO:0001968 fibronectin binding 3/279 30/18639 0.1 6.68064516129032 0.00999354025673981 0.160050892739861 GO:0031210 phosphatidylcholine binding 3/279 30/18639 0.1 6.68064516129032 0.00999354025673981 0.160050892739861 GO:0016651 oxidoreductase activity, acting on NAD(P)H 5/279 88/18639 0.0568181818181818 3.7958211143695 0.010356991897057 0.160050892739861 GO:0016504 peptidase activator activity 4/279 57/18639 0.0701754385964912 4.68817204301075 0.0104267682566684 0.160050892739861 GO:0005178 integrin binding 7/279 161/18639 0.0434782608695652 2.90462833099579 0.0108196841928434 0.162031368156241 GO:0008526 phosphatidylinositol transfer activity 2/279 11/18639 0.181818181818182 12.1466275659824 0.0112320181690142 0.164201408470827 GO:0003714 transcription corepressor activity 8/279 204/18639 0.0392156862745098 2.61986084756483 0.0119429681728592 0.170534475770595 GO:0015399 primary active transmembrane transporter activity 7/279 166/18639 0.0421686746987952 2.81713952584532 0.0126448161191556 0.176452661299126 GO:0051015 actin filament binding 8/279 209/18639 0.0382775119617225 2.55718475073314 0.0136566126402814 0.186336892469617 GO:0003713 transcription coactivator activity 9/279 256/18639 0.03515625 2.34866431451613 0.0153021909266439 0.204250983238247 GO:0140297 DNA-binding transcription factor binding 14/279 488/18639 0.0286885245901639 1.91657852987837 0.0156496180645028 0.204443946629887 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 11/279 349/18639 0.0315186246418338 2.10564747203993 0.016461851445153 0.210574516402583 GO:0004175 endopeptidase activity 12/279 405/18639 0.0296296296296296 1.9794504181601 0.0194226742193572 0.234258505187504 GO:0005041 low-density lipoprotein particle receptor activity 2/279 15/18639 0.133333333333333 8.90752688172043 0.0206162153903608 0.234258505187504 GO:0015929 hexosaminidase activity 2/279 15/18639 0.133333333333333 8.90752688172043 0.0206162153903608 0.234258505187504 GO:0042809 nuclear vitamin D receptor binding 2/279 15/18639 0.133333333333333 8.90752688172043 0.0206162153903608 0.234258505187504 GO:0140776 protein-containing complex destabilizing activity 2/279 15/18639 0.133333333333333 8.90752688172043 0.0206162153903608 0.234258505187504 GO:0097110 scaffold protein binding 4/279 70/18639 0.0571428571428571 3.81751152073733 0.0208343333396064 0.234258505187504 GO:0015078 proton transmembrane transporter activity 7/279 185/18639 0.0378378378378378 2.52781168265039 0.0216151867890098 0.234258505187504 GO:0050997 quaternary ammonium group binding 3/279 40/18639 0.075 5.01048387096774 0.0218058750020991 0.234258505187504 GO:0140662 ATP-dependent protein folding chaperone 3/279 40/18639 0.075 5.01048387096774 0.0218058750020991 0.234258505187504 GO:0005518 collagen binding 4/279 72/18639 0.0555555555555556 3.71146953405018 0.0228463244412429 0.234258505187504 GO:1901681 sulfur compound binding 9/279 275/18639 0.0327272727272727 2.18639296187683 0.023132473421784 0.234258505187504 GO:0004812 aminoacyl-tRNA ligase activity 3/279 41/18639 0.0731707317073171 4.8882769472856 0.0232732391147195 0.234258505187504 GO:0016875 ligase activity, forming carbon-oxygen bonds 3/279 41/18639 0.0731707317073171 4.8882769472856 0.0232732391147195 0.234258505187504 GO:0042056 chemoattractant activity 3/279 42/18639 0.0714285714285714 4.77188940092166 0.0247929598127387 0.245274249714827 GO:0008429 phosphatidylethanolamine binding 2/279 17/18639 0.117647058823529 7.8595825426945 0.0261850363257193 0.245274249714827 GO:0032183 SUMO binding 2/279 17/18639 0.117647058823529 7.8595825426945 0.0261850363257193 0.245274249714827 GO:0051787 misfolded protein binding 2/279 17/18639 0.117647058823529 7.8595825426945 0.0261850363257193 0.245274249714827 GO:0048156 tau protein binding 3/279 43/18639 0.0697674418604651 4.6609152288072 0.0263649844970335 0.245274249714827 GO:0008525 phosphatidylcholine transporter activity 2/279 18/18639 0.111111111111111 7.42293906810036 0.029171660245039 0.263402932212558 GO:0030228 lipoprotein particle receptor activity 2/279 18/18639 0.111111111111111 7.42293906810036 0.029171660245039 0.263402932212558 GO:0008009 chemokine activity 3/279 45/18639 0.0666666666666667 4.45376344086021 0.0296655507930808 0.263980408506545 GO:0046332 SMAD binding 4/279 79/18639 0.0506329113924051 3.38260514495713 0.0307962842500816 0.270127407565002 GO:0046624 sphingolipid transporter activity 2/279 19/18639 0.105263157894737 7.03225806451613 0.0322869264535513 0.271564011540829 GO:0097001 ceramide binding 2/279 19/18639 0.105263157894737 7.03225806451613 0.0322869264535513 0.271564011540829 GO:1990380 K48-linked deubiquitinase activity 2/279 19/18639 0.105263157894737 7.03225806451613 0.0322869264535513 0.271564011540829 GO:0001664 G protein-coupled receptor binding 9/279 297/18639 0.0303030303030303 2.02443792766373 0.0353693415031244 0.29084233739371 GO:0042288 MHC class I protein binding 2/279 20/18639 0.1 6.68064516129032 0.0355263441441828 0.29084233739371 GO:0048020 CCR chemokine receptor binding 3/279 50/18639 0.06 4.00838709677419 0.03882180531195 0.313639321862333 GO:0016209 antioxidant activity 4/279 86/18639 0.0465116279069767 3.1072768192048 0.0401868146805051 0.320450704075716 GO:0019783 ubiquitin-like protein peptidase activity 5/279 127/18639 0.0393700787401575 2.63017526035052 0.0423019803515883 0.329229850468255 GO:0140517 protein-RNA adaptor activity 2/279 22/18639 0.0909090909090909 6.0733137829912 0.0423601924869578 0.329229850468255 GO:0003727 single-stranded RNA binding 4/279 89/18639 0.0449438202247191 3.00253715114172 0.0446568154823874 0.34173535324397 GO:0008201 heparin binding 6/279 172/18639 0.0348837209302326 2.3304576144036 0.0450823511608495 0.34173535324397 GO:0005158 insulin receptor binding 2/279 23/18639 0.0869565217391304 5.80925666199158 0.0459461569724044 0.344035858305565 GO:0140463 chromatin-protein adaptor activity 3/279 54/18639 0.0555555555555556 3.71146953405018 0.0470599178631755 0.344916804697485 GO:0031072 heat shock protein binding 5/279 131/18639 0.0381679389312977 2.54986456537799 0.0472433557824506 0.344916804697485 GO:0072341 modified amino acid binding 4/279 91/18639 0.043956043956044 2.9365473236441 0.0477853278395942 0.344916804697485 GO:0003735 structural constituent of ribosome 6/279 175/18639 0.0342857142857143 2.2905069124424 0.0483108228077911 0.344916804697485 GO:0098632 cell-cell adhesion mediator activity 3/279 55/18639 0.0545454545454545 3.64398826979472 0.0492433705922337 0.347533672915305 GO:0120020 cholesterol transfer activity 2/279 25/18639 0.08 5.34451612903226 0.0534357433916725 0.370856381945038 GO:0004601 peroxidase activity 3/279 57/18639 0.0526315789473684 3.51612903225806 0.0537560553633687 0.370856381945038 GO:0016407 acetyltransferase activity 4/279 96/18639 0.0416666666666667 2.78360215053763 0.0561239076291353 0.376302447236113 GO:0030247 polysaccharide binding 2/279 26/18639 0.0769230769230769 5.13895781637717 0.0573314845656794 0.376302447236113 GO:0120014 phospholipid transfer activity 2/279 26/18639 0.0769230769230769 5.13895781637717 0.0573314845656794 0.376302447236113 GO:0001786 phosphatidylserine binding 3/279 59/18639 0.0508474576271186 3.39693821760525 0.0584600130222543 0.376302447236113 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/279 59/18639 0.0508474576271186 3.39693821760525 0.0584600130222543 0.376302447236113 GO:0070063 RNA polymerase binding 3/279 59/18639 0.0508474576271186 3.39693821760525 0.0584600130222543 0.376302447236113 GO:0061135 endopeptidase regulator activity 6/279 184/18639 0.0326086956521739 2.17847124824684 0.058835561782845 0.376302447236113 GO:0004713 protein tyrosine kinase activity 5/279 140/18639 0.0357142857142857 2.38594470046083 0.0595640323271504 0.377034184008973 GO:0005044 scavenger receptor activity 2/279 27/18639 0.0740740740740741 4.94862604540024 0.0613227596193116 0.38420586128834 GO:0046625 sphingolipid binding 2/279 28/18639 0.0714285714285714 4.77188940092166 0.0654058589409348 0.394733435954729 GO:0046966 nuclear thyroid hormone receptor binding 2/279 28/18639 0.0714285714285714 4.77188940092166 0.0654058589409348 0.394733435954729 GO:0097718 disordered domain specific binding 2/279 28/18639 0.0714285714285714 4.77188940092166 0.0654058589409348 0.394733435954729 GO:0019903 protein phosphatase binding 5/279 144/18639 0.0347222222222222 2.31966845878136 0.0655746098817302 0.394733435954729 GO:0019902 phosphatase binding 6/279 190/18639 0.0315789473684211 2.10967741935484 0.0665565875968436 0.39675480373264 GO:0003779 actin binding 11/279 443/18639 0.0248306997742664 1.65885094298405 0.0704900445594072 0.415904080611767 GO:0005539 glycosaminoglycan binding 7/279 242/18639 0.0289256198347107 1.93241802186084 0.0723354939599499 0.415904080611767 GO:0019843 rRNA binding 3/279 65/18639 0.0461538461538462 3.0833746898263 0.0736784593654742 0.415904080611767 GO:0038024 cargo receptor activity 3/279 65/18639 0.0461538461538462 3.0833746898263 0.0736784593654742 0.415904080611767 GO:0120013 lipid transfer activity 3/279 65/18639 0.0461538461538462 3.0833746898263 0.0736784593654742 0.415904080611767 GO:0070566 adenylyltransferase activity 2/279 30/18639 0.0666666666666667 4.45376344086021 0.0738331348317306 0.415904080611767 GO:0019888 protein phosphatase regulator activity 4/279 107/18639 0.0373831775700935 2.49743744347302 0.077021720567013 0.429921240255873 GO:0004843 cysteine-type deubiquitinase activity 4/279 108/18639 0.037037037037037 2.47431302270012 0.0790910964464499 0.433666162330181 GO:0050840 extracellular matrix binding 3/279 67/18639 0.0447761194029851 2.9913336543091 0.0791052283077854 0.433666162330181 GO:1990841 promoter-specific chromatin binding 3/279 68/18639 0.0441176470588235 2.94734345351044 0.0818823032610686 0.444801968236819 GO:0120015 sterol transfer activity 2/279 32/18639 0.0625 4.17540322580645 0.0825853817247514 0.444801968236819 GO:0004222 metalloendopeptidase activity 4/279 110/18639 0.0363636363636364 2.42932551319648 0.0833122703501275 0.444815078217202 GO:0008080 N-acetyltransferase activity 3/279 69/18639 0.0434782608695652 2.90462833099579 0.0847010087585463 0.448331201532305 GO:0140416 transcription regulator inhibitor activity 2/279 33/18639 0.0606060606060606 4.04887585532747 0.0870750083169953 0.456035632877644 GO:0005200 structural constituent of cytoskeleton 4/279 112/18639 0.0357142857142857 2.38594470046083 0.0876420271654104 0.456035632877644 GO:0051427 hormone receptor binding 2/279 34/18639 0.0588235294117647 3.92979127134725 0.0916360069056644 0.465294304212953 GO:0042379 chemokine receptor binding 3/279 72/18639 0.0416666666666667 2.78360215053763 0.0934005244618236 0.465294304212953 GO:0017124 SH3 domain binding 4/279 115/18639 0.0347826086956522 2.32370266479663 0.0943365864256794 0.465294304212953 GO:0035401 histone H3Y41 kinase activity 4/279 115/18639 0.0347826086956522 2.32370266479663 0.0943365864256794 0.465294304212953 GO:0101005 deubiquitinase activity 4/279 115/18639 0.0347826086956522 2.32370266479663 0.0943365864256794 0.465294304212953 GO:0140801 histone H2AXY142 kinase activity 4/279 115/18639 0.0347826086956522 2.32370266479663 0.0943365864256794 0.465294304212953 GO:0004866 endopeptidase inhibitor activity 5/279 161/18639 0.031055900621118 2.07473452213985 0.0947260391313014 0.465294304212953 GO:0140566 histone reader activity 2/279 35/18639 0.0571428571428571 3.81751152073733 0.096265253511784 0.469102108382821 GO:0016887 ATP hydrolysis activity 10/279 417/18639 0.0239808153477218 1.60207318016555 0.0975658251369035 0.471696193968967 GO:0019208 phosphatase regulator activity 4/279 117/18639 0.0341880341880342 2.28398125172319 0.0989303058080334 0.473096570297408 GO:0031491 nucleosome binding 3/279 74/18639 0.0405405405405405 2.70836965998256 0.0993965106976639 0.473096570297408 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/279 36/18639 0.0555555555555556 3.71146953405018 0.100959701083563 0.476840434348518 GO:0044183 protein folding chaperone 3/279 75/18639 0.04 2.67225806451613 0.102451402966646 0.480192071920003 GO:0098631 cell adhesion mediator activity 3/279 76/18639 0.0394736842105263 2.63709677419355 0.105543328003567 0.490936389349927 GO:0016874 ligase activity 5/279 167/18639 0.029940119760479 2.00019316206297 0.106363570061611 0.491031819682927 GO:0030414 peptidase inhibitor activity 5/279 169/18639 0.029585798816568 1.97652223706814 0.110392481290413 0.500491307706086 GO:0042162 telomeric DNA binding 2/279 38/18639 0.0526315789473684 3.51612903225806 0.110532386047401 0.500491307706086 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/279 122/18639 0.0327868852459016 2.19037546271814 0.110858009524475 0.500491307706086 GO:0016835 carbon-oxygen lyase activity 3/279 79/18639 0.0379746835443038 2.53695385871784 0.115034464906628 0.511820010526591 GO:0033293 monocarboxylic acid binding 3/279 79/18639 0.0379746835443038 2.53695385871784 0.115034464906628 0.511820010526591 GO:0005126 cytokine receptor binding 7/279 275/18639 0.0254545454545455 1.70052785923754 0.12002388777372 0.530177461101182 GO:0001618 virus receptor activity 3/279 81/18639 0.037037037037037 2.47431302270012 0.121534454756277 0.533015394431101 GO:0042826 histone deacetylase binding 4/279 127/18639 0.031496062992126 2.10414020828042 0.123393353419393 0.537123554808106 GO:0140272 exogenous protein binding 3/279 82/18639 0.0365853658536585 2.4441384736428 0.124834132157915 0.537123554808106 GO:0042287 MHC protein binding 2/279 41/18639 0.0487804878048781 3.2588512981904 0.125308493778116 0.537123554808106 GO:0031490 chromatin DNA binding 4/279 128/18639 0.03125 2.08770161290323 0.125970345101575 0.537123554808106 GO:0005543 phospholipid binding 11/279 497/18639 0.0221327967806841 1.47861361718699 0.128054527712459 0.539249432862162 GO:0031492 nucleosomal DNA binding 2/279 42/18639 0.0476190476190476 3.18125960061444 0.130334270476385 0.539249432862162 GO:0043175 RNA polymerase core enzyme binding 2/279 42/18639 0.0476190476190476 3.18125960061444 0.130334270476385 0.539249432862162 GO:0048487 beta-tubulin binding 2/279 42/18639 0.0476190476190476 3.18125960061444 0.130334270476385 0.539249432862162 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/279 132/18639 0.0303030303030303 2.02443792766373 0.136501837422002 0.539249432862162 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/279 10/18639 0.1 6.68064516129032 0.140027137890217 0.539249432862162 GO:0004090 carbonyl reductase (NADPH) activity 1/279 10/18639 0.1 6.68064516129032 0.140027137890217 0.539249432862162 GO:0005131 growth hormone receptor binding 1/279 10/18639 0.1 6.68064516129032 0.140027137890217 0.539249432862162 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/279 10/18639 0.1 6.68064516129032 0.140027137890217 0.539249432862162 GO:0031720 haptoglobin binding 1/279 10/18639 0.1 6.68064516129032 0.140027137890217 0.539249432862162 GO:0043208 glycosphingolipid binding 1/279 10/18639 0.1 6.68064516129032 0.140027137890217 0.539249432862162 GO:0043295 glutathione binding 1/279 10/18639 0.1 6.68064516129032 0.140027137890217 0.539249432862162 GO:0043422 protein kinase B binding 1/279 10/18639 0.1 6.68064516129032 0.140027137890217 0.539249432862162 GO:0047429 nucleoside triphosphate diphosphatase activity 1/279 10/18639 0.1 6.68064516129032 0.140027137890217 0.539249432862162 GO:0097177 mitochondrial ribosome binding 1/279 10/18639 0.1 6.68064516129032 0.140027137890217 0.539249432862162 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/279 44/18639 0.0454545454545455 3.0366568914956 0.140521024850075 0.539249432862162 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/279 45/18639 0.0444444444444444 2.96917562724014 0.145677093410865 0.540669609553726 GO:0002020 protease binding 4/279 136/18639 0.0294117647058824 1.96489563567362 0.147376673726284 0.540669609553726 GO:0016922 nuclear receptor binding 4/279 137/18639 0.0291970802919708 1.9505533317636 0.150146744062832 0.540669609553726 GO:0001851 complement component C3b binding 1/279 11/18639 0.0909090909090909 6.0733137829912 0.152906649862337 0.540669609553726 GO:0008199 ferric iron binding 1/279 11/18639 0.0909090909090909 6.0733137829912 0.152906649862337 0.540669609553726 GO:0008271 secondary active sulfate transmembrane transporter activity 1/279 11/18639 0.0909090909090909 6.0733137829912 0.152906649862337 0.540669609553726 GO:0019864 IgG binding 1/279 11/18639 0.0909090909090909 6.0733137829912 0.152906649862337 0.540669609553726 GO:0034713 type I transforming growth factor beta receptor binding 1/279 11/18639 0.0909090909090909 6.0733137829912 0.152906649862337 0.540669609553726 GO:0048185 activin binding 1/279 11/18639 0.0909090909090909 6.0733137829912 0.152906649862337 0.540669609553726 GO:0048407 platelet-derived growth factor binding 1/279 11/18639 0.0909090909090909 6.0733137829912 0.152906649862337 0.540669609553726 GO:1900750 oligopeptide binding 1/279 11/18639 0.0909090909090909 6.0733137829912 0.152906649862337 0.540669609553726 GO:0005504 fatty acid binding 2/279 47/18639 0.0425531914893617 2.84282772820865 0.156102809962401 0.540669609553726 GO:0000340 RNA 7-methylguanosine cap binding 1/279 12/18639 0.0833333333333333 5.56720430107527 0.165593950951472 0.540669609553726 GO:0004300 enoyl-CoA hydratase activity 1/279 12/18639 0.0833333333333333 5.56720430107527 0.165593950951472 0.540669609553726 GO:0004859 phospholipase inhibitor activity 1/279 12/18639 0.0833333333333333 5.56720430107527 0.165593950951472 0.540669609553726 GO:0005078 MAP-kinase scaffold activity 1/279 12/18639 0.0833333333333333 5.56720430107527 0.165593950951472 0.540669609553726 GO:0017166 vinculin binding 1/279 12/18639 0.0833333333333333 5.56720430107527 0.165593950951472 0.540669609553726 GO:0031543 peptidyl-proline dioxygenase activity 1/279 12/18639 0.0833333333333333 5.56720430107527 0.165593950951472 0.540669609553726 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/279 12/18639 0.0833333333333333 5.56720430107527 0.165593950951472 0.540669609553726 GO:0035197 siRNA binding 1/279 12/18639 0.0833333333333333 5.56720430107527 0.165593950951472 0.540669609553726 GO:0035497 cAMP response element binding 1/279 12/18639 0.0833333333333333 5.56720430107527 0.165593950951472 0.540669609553726 GO:0070410 co-SMAD binding 1/279 12/18639 0.0833333333333333 5.56720430107527 0.165593950951472 0.540669609553726 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/279 12/18639 0.0833333333333333 5.56720430107527 0.165593950951472 0.540669609553726 GO:1990817 poly(A) RNA polymerase activity 1/279 12/18639 0.0833333333333333 5.56720430107527 0.165593950951472 0.540669609553726 GO:0016410 N-acyltransferase activity 3/279 94/18639 0.0319148936170213 2.13212079615649 0.166739971491159 0.540669609553726 GO:0004867 serine-type endopeptidase inhibitor activity 3/279 95/18639 0.0315789473684211 2.10967741935484 0.170403318491431 0.540669609553726 GO:0140104 molecular carrier activity 6/279 249/18639 0.0240963855421687 1.60979401476875 0.1711660231064 0.540669609553726 GO:0004857 enzyme inhibitor activity 9/279 416/18639 0.0216346153846154 1.44533188585608 0.173320835330189 0.540669609553726 GO:0030544 Hsp70 protein binding 2/279 51/18639 0.0392156862745098 2.61986084756483 0.177346242015748 0.540669609553726 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/279 13/18639 0.0769230769230769 5.13895781637717 0.178091899503818 0.540669609553726 GO:0005172 vascular endothelial growth factor receptor binding 1/279 13/18639 0.0769230769230769 5.13895781637717 0.178091899503818 0.540669609553726 GO:0008035 high-density lipoprotein particle binding 1/279 13/18639 0.0769230769230769 5.13895781637717 0.178091899503818 0.540669609553726 GO:0019104 DNA N-glycosylase activity 1/279 13/18639 0.0769230769230769 5.13895781637717 0.178091899503818 0.540669609553726 GO:0019855 calcium channel inhibitor activity 1/279 13/18639 0.0769230769230769 5.13895781637717 0.178091899503818 0.540669609553726 GO:0046974 histone H3K9 methyltransferase activity 1/279 13/18639 0.0769230769230769 5.13895781637717 0.178091899503818 0.540669609553726 GO:0051011 microtubule minus-end binding 1/279 13/18639 0.0769230769230769 5.13895781637717 0.178091899503818 0.540669609553726 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/279 13/18639 0.0769230769230769 5.13895781637717 0.178091899503818 0.540669609553726 GO:0140666 annealing activity 1/279 13/18639 0.0769230769230769 5.13895781637717 0.178091899503818 0.540669609553726 GO:0005080 protein kinase C binding 2/279 52/18639 0.0384615384615385 2.56947890818859 0.182726454099159 0.540669609553726 GO:0016860 intramolecular oxidoreductase activity 2/279 53/18639 0.0377358490566038 2.52099817407182 0.188130407662378 0.540669609553726 GO:0051018 protein kinase A binding 2/279 53/18639 0.0377358490566038 2.52099817407182 0.188130407662378 0.540669609553726 GO:0140296 general transcription initiation factor binding 2/279 53/18639 0.0377358490566038 2.52099817407182 0.188130407662378 0.540669609553726 GO:0005344 oxygen carrier activity 1/279 14/18639 0.0714285714285714 4.77188940092166 0.190403311510606 0.540669609553726 GO:0008191 metalloendopeptidase inhibitor activity 1/279 14/18639 0.0714285714285714 4.77188940092166 0.190403311510606 0.540669609553726 GO:0008195 phosphatidate phosphatase activity 1/279 14/18639 0.0714285714285714 4.77188940092166 0.190403311510606 0.540669609553726 GO:0008559 ABC-type xenobiotic transporter activity 1/279 14/18639 0.0714285714285714 4.77188940092166 0.190403311510606 0.540669609553726 GO:0019763 immunoglobulin receptor activity 1/279 14/18639 0.0714285714285714 4.77188940092166 0.190403311510606 0.540669609553726 GO:0019992 diacylglycerol binding 1/279 14/18639 0.0714285714285714 4.77188940092166 0.190403311510606 0.540669609553726 GO:0030983 mismatched DNA binding 1/279 14/18639 0.0714285714285714 4.77188940092166 0.190403311510606 0.540669609553726 GO:0031404 chloride ion binding 1/279 14/18639 0.0714285714285714 4.77188940092166 0.190403311510606 0.540669609553726 GO:0034236 protein kinase A catalytic subunit binding 1/279 14/18639 0.0714285714285714 4.77188940092166 0.190403311510606 0.540669609553726 GO:0043176 amine binding 1/279 14/18639 0.0714285714285714 4.77188940092166 0.190403311510606 0.540669609553726 GO:0044548 S100 protein binding 1/279 14/18639 0.0714285714285714 4.77188940092166 0.190403311510606 0.540669609553726 GO:0061665 SUMO ligase activity 1/279 14/18639 0.0714285714285714 4.77188940092166 0.190403311510606 0.540669609553726 GO:0071933 Arp2/3 complex binding 1/279 14/18639 0.0714285714285714 4.77188940092166 0.190403311510606 0.540669609553726 GO:1990825 sequence-specific mRNA binding 1/279 14/18639 0.0714285714285714 4.77188940092166 0.190403311510606 0.540669609553726 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/279 54/18639 0.037037037037037 2.47431302270012 0.193556195731578 0.540669609553726 GO:0017069 snRNA binding 2/279 54/18639 0.037037037037037 2.47431302270012 0.193556195731578 0.540669609553726 GO:0051287 NAD binding 2/279 54/18639 0.037037037037037 2.47431302270012 0.193556195731578 0.540669609553726 GO:0051020 GTPase binding 7/279 315/18639 0.0222222222222222 1.48458781362007 0.194597636428365 0.540669609553726 GO:0003730 mRNA 3'-UTR binding 6/279 262/18639 0.0229007633587786 1.52991873922679 0.200319083978433 0.540669609553726 GO:0004129 cytochrome-c oxidase activity 1/279 15/18639 0.0666666666666667 4.45376344086021 0.20253096123348 0.540669609553726 GO:0015116 sulfate transmembrane transporter activity 1/279 15/18639 0.0666666666666667 4.45376344086021 0.20253096123348 0.540669609553726 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/279 15/18639 0.0666666666666667 4.45376344086021 0.20253096123348 0.540669609553726 GO:0031386 protein tag activity 1/279 15/18639 0.0666666666666667 4.45376344086021 0.20253096123348 0.540669609553726 GO:0045504 dynein heavy chain binding 1/279 15/18639 0.0666666666666667 4.45376344086021 0.20253096123348 0.540669609553726 GO:0050780 dopamine receptor binding 1/279 15/18639 0.0666666666666667 4.45376344086021 0.20253096123348 0.540669609553726 GO:0051371 muscle alpha-actinin binding 1/279 15/18639 0.0666666666666667 4.45376344086021 0.20253096123348 0.540669609553726 GO:0061578 K63-linked deubiquitinase activity 1/279 15/18639 0.0666666666666667 4.45376344086021 0.20253096123348 0.540669609553726 GO:0141047 molecular tag activity 1/279 15/18639 0.0666666666666667 4.45376344086021 0.20253096123348 0.540669609553726 GO:0140375 immune receptor activity 4/279 156/18639 0.0256410256410256 1.71298593879239 0.206196966053359 0.546428361982958 GO:0000062 fatty-acyl-CoA binding 1/279 16/18639 0.0625 4.17540322580645 0.214477581820672 0.546428361982958 GO:0003688 DNA replication origin binding 1/279 16/18639 0.0625 4.17540322580645 0.214477581820672 0.546428361982958 GO:0004708 MAP kinase kinase activity 1/279 16/18639 0.0625 4.17540322580645 0.214477581820672 0.546428361982958 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/279 16/18639 0.0625 4.17540322580645 0.214477581820672 0.546428361982958 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/279 16/18639 0.0625 4.17540322580645 0.214477581820672 0.546428361982958 GO:0017070 U6 snRNA binding 1/279 16/18639 0.0625 4.17540322580645 0.214477581820672 0.546428361982958 GO:0043023 ribosomal large subunit binding 1/279 16/18639 0.0625 4.17540322580645 0.214477581820672 0.546428361982958 GO:0055102 lipase inhibitor activity 1/279 16/18639 0.0625 4.17540322580645 0.214477581820672 0.546428361982958 GO:0070411 I-SMAD binding 1/279 16/18639 0.0625 4.17540322580645 0.214477581820672 0.546428361982958 GO:0097027 ubiquitin-protein transferase activator activity 1/279 16/18639 0.0625 4.17540322580645 0.214477581820672 0.546428361982958 GO:0061980 regulatory RNA binding 2/279 58/18639 0.0344827586206897 2.30367074527252 0.215441329080985 0.546615603536052 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/279 17/18639 0.0588235294117647 3.92979127134725 0.226245865914107 0.560140974480894 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/279 17/18639 0.0588235294117647 3.92979127134725 0.226245865914107 0.560140974480894 GO:0032977 membrane insertase activity 1/279 17/18639 0.0588235294117647 3.92979127134725 0.226245865914107 0.560140974480894 GO:0048038 quinone binding 1/279 17/18639 0.0588235294117647 3.92979127134725 0.226245865914107 0.560140974480894 GO:0070403 NAD+ binding 1/279 17/18639 0.0588235294117647 3.92979127134725 0.226245865914107 0.560140974480894 GO:1901567 fatty acid derivative binding 1/279 17/18639 0.0588235294117647 3.92979127134725 0.226245865914107 0.560140974480894 GO:0016836 hydro-lyase activity 2/279 61/18639 0.0327868852459016 2.19037546271814 0.231998410235774 0.568221082786051 GO:0003746 translation elongation factor activity 1/279 18/18639 0.0555555555555556 3.71146953405018 0.237838466247581 0.568221082786051 GO:0015172 acidic amino acid transmembrane transporter activity 1/279 18/18639 0.0555555555555556 3.71146953405018 0.237838466247581 0.568221082786051 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/279 18/18639 0.0555555555555556 3.71146953405018 0.237838466247581 0.568221082786051 GO:0017075 syntaxin-1 binding 1/279 18/18639 0.0555555555555556 3.71146953405018 0.237838466247581 0.568221082786051 GO:0070064 proline-rich region binding 1/279 18/18639 0.0555555555555556 3.71146953405018 0.237838466247581 0.568221082786051 GO:0098641 cadherin binding involved in cell-cell adhesion 1/279 18/18639 0.0555555555555556 3.71146953405018 0.237838466247581 0.568221082786051 GO:1901611 phosphatidylglycerol binding 1/279 18/18639 0.0555555555555556 3.71146953405018 0.237838466247581 0.568221082786051 GO:1990381 ubiquitin-specific protease binding 1/279 18/18639 0.0555555555555556 3.71146953405018 0.237838466247581 0.568221082786051 GO:1901682 sulfur compound transmembrane transporter activity 2/279 63/18639 0.0317460317460317 2.12083973374296 0.243080772853431 0.573200036288349 GO:0022804 active transmembrane transporter activity 9/279 457/18639 0.0196936542669584 1.3156631608668 0.247384880070021 0.573200036288349 GO:0003756 protein disulfide isomerase activity 1/279 19/18639 0.0526315789473684 3.51612903225806 0.249257996236139 0.573200036288349 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/279 19/18639 0.0526315789473684 3.51612903225806 0.249257996236139 0.573200036288349 GO:0030506 ankyrin binding 1/279 19/18639 0.0526315789473684 3.51612903225806 0.249257996236139 0.573200036288349 GO:0031420 alkali metal ion binding 1/279 19/18639 0.0526315789473684 3.51612903225806 0.249257996236139 0.573200036288349 GO:0042577 lipid phosphatase activity 1/279 19/18639 0.0526315789473684 3.51612903225806 0.249257996236139 0.573200036288349 GO:0043395 heparan sulfate proteoglycan binding 1/279 19/18639 0.0526315789473684 3.51612903225806 0.249257996236139 0.573200036288349 GO:0120227 acyl-CoA binding 1/279 19/18639 0.0526315789473684 3.51612903225806 0.249257996236139 0.573200036288349 GO:0140036 ubiquitin-modified protein reader activity 1/279 19/18639 0.0526315789473684 3.51612903225806 0.249257996236139 0.573200036288349 GO:0031267 small GTPase binding 6/279 283/18639 0.0212014134275618 1.41639120027357 0.250829906197432 0.574662546288147 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 5/279 229/18639 0.0218340611353712 1.45865614875335 0.259500308401879 0.577441576757601 GO:0000339 RNA cap binding 1/279 20/18639 0.05 3.34032258064516 0.260507030556768 0.577441576757601 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/279 20/18639 0.05 3.34032258064516 0.260507030556768 0.577441576757601 GO:0016004 phospholipase activator activity 1/279 20/18639 0.05 3.34032258064516 0.260507030556768 0.577441576757601 GO:0016408 C-acyltransferase activity 1/279 20/18639 0.05 3.34032258064516 0.260507030556768 0.577441576757601 GO:0016505 peptidase activator activity involved in apoptotic process 1/279 20/18639 0.05 3.34032258064516 0.260507030556768 0.577441576757601 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/279 20/18639 0.05 3.34032258064516 0.260507030556768 0.577441576757601 GO:0031418 L-ascorbic acid binding 1/279 20/18639 0.05 3.34032258064516 0.260507030556768 0.577441576757601 GO:0043024 ribosomal small subunit binding 1/279 20/18639 0.05 3.34032258064516 0.260507030556768 0.577441576757601 GO:0000287 magnesium ion binding 5/279 230/18639 0.0217391304347826 1.4523141654979 0.262330585911889 0.579392013488849 GO:0005548 phospholipid transporter activity 2/279 68/18639 0.0294117647058824 1.96489563567362 0.270857681577525 0.58150585132382 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/279 21/18639 0.0476190476190476 3.18125960061444 0.271588105720561 0.58150585132382 GO:0001846 opsonin binding 1/279 21/18639 0.0476190476190476 3.18125960061444 0.271588105720561 0.58150585132382 GO:0035613 RNA stem-loop binding 1/279 21/18639 0.0476190476190476 3.18125960061444 0.271588105720561 0.58150585132382 GO:0051428 peptide hormone receptor binding 1/279 21/18639 0.0476190476190476 3.18125960061444 0.271588105720561 0.58150585132382 GO:0061891 calcium ion sensor activity 1/279 21/18639 0.0476190476190476 3.18125960061444 0.271588105720561 0.58150585132382 GO:0072542 protein phosphatase activator activity 1/279 21/18639 0.0476190476190476 3.18125960061444 0.271588105720561 0.58150585132382 GO:0003697 single-stranded DNA binding 3/279 121/18639 0.0247933884297521 1.65635830445215 0.271811366986867 0.58150585132382 GO:0051082 unfolded protein binding 3/279 121/18639 0.0247933884297521 1.65635830445215 0.271811366986867 0.58150585132382 GO:0005125 cytokine activity 5/279 234/18639 0.0213675213675214 1.42748828232699 0.27372189798802 0.583559879738349 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/279 22/18639 0.0454545454545455 3.0366568914956 0.282503720636447 0.589990763506049 GO:0034062 5'-3' RNA polymerase activity 1/279 22/18639 0.0454545454545455 3.0366568914956 0.282503720636447 0.589990763506049 GO:0061133 endopeptidase activator activity 1/279 22/18639 0.0454545454545455 3.0366568914956 0.282503720636447 0.589990763506049 GO:0097747 RNA polymerase activity 1/279 22/18639 0.0454545454545455 3.0366568914956 0.282503720636447 0.589990763506049 GO:0140035 ubiquitin-like protein reader activity 1/279 22/18639 0.0454545454545455 3.0366568914956 0.282503720636447 0.589990763506049 GO:0140784 metal ion sensor activity 1/279 22/18639 0.0454545454545455 3.0366568914956 0.282503720636447 0.589990763506049 GO:0140299 molecular sensor activity 2/279 71/18639 0.028169014084507 1.88187187641981 0.287520090132166 0.597250108411068 GO:0004602 glutathione peroxidase activity 1/279 23/18639 0.0434782608695652 2.90462833099579 0.293256337166631 0.597250108411068 GO:0008171 O-methyltransferase activity 1/279 23/18639 0.0434782608695652 2.90462833099579 0.293256337166631 0.597250108411068 GO:0031681 G-protein beta-subunit binding 1/279 23/18639 0.0434782608695652 2.90462833099579 0.293256337166631 0.597250108411068 GO:0070577 lysine-acetylated histone binding 1/279 23/18639 0.0434782608695652 2.90462833099579 0.293256337166631 0.597250108411068 GO:0008237 metallopeptidase activity 4/279 184/18639 0.0217391304347826 1.4523141654979 0.297188124287257 0.597250108411068 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 9/279 484/18639 0.0185950413223141 1.24226872833911 0.301181031077738 0.597250108411068 GO:0005315 phosphate transmembrane transporter activity 1/279 24/18639 0.0416666666666667 2.78360215053763 0.303848380673856 0.597250108411068 GO:0005540 hyaluronic acid binding 1/279 24/18639 0.0416666666666667 2.78360215053763 0.303848380673856 0.597250108411068 GO:0060229 lipase activator activity 1/279 24/18639 0.0416666666666667 2.78360215053763 0.303848380673856 0.597250108411068 GO:0070300 phosphatidic acid binding 1/279 24/18639 0.0416666666666667 2.78360215053763 0.303848380673856 0.597250108411068 GO:0140033 acetylation-dependent protein binding 1/279 24/18639 0.0416666666666667 2.78360215053763 0.303848380673856 0.597250108411068 GO:0003678 DNA helicase activity 2/279 74/18639 0.027027027027027 1.80557977332171 0.304140463671114 0.597250108411068 GO:0003684 damaged DNA binding 2/279 74/18639 0.027027027027027 1.80557977332171 0.304140463671114 0.597250108411068 GO:0048029 monosaccharide binding 2/279 74/18639 0.027027027027027 1.80557977332171 0.304140463671114 0.597250108411068 GO:0035591 signaling adaptor activity 3/279 129/18639 0.0232558139534884 1.5536384096024 0.304414375709738 0.597250108411068 GO:0031406 carboxylic acid binding 4/279 187/18639 0.0213903743315508 1.42901500776264 0.307280063612238 0.597250108411068 GO:0016798 hydrolase activity, acting on glycosyl bonds 3/279 130/18639 0.0230769230769231 1.54168734491315 0.308506243493527 0.597250108411068 GO:0019003 GDP binding 2/279 75/18639 0.0266666666666667 1.78150537634409 0.309666191361648 0.597250108411068 GO:0140597 protein carrier chaperone 4/279 188/18639 0.0212765957446809 1.42141386410432 0.310652234687255 0.597250108411068 GO:0043177 organic acid binding 4/279 189/18639 0.0211640211640212 1.41389315582864 0.314028014602323 0.597250108411068 GO:0001848 complement binding 1/279 25/18639 0.04 2.67225806451613 0.314282240560614 0.597250108411068 GO:0005537 D-mannose binding 1/279 25/18639 0.04 2.67225806451613 0.314282240560614 0.597250108411068 GO:0019211 phosphatase activator activity 1/279 25/18639 0.04 2.67225806451613 0.314282240560614 0.597250108411068 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/279 25/18639 0.04 2.67225806451613 0.314282240560614 0.597250108411068 GO:0019707 protein-cysteine S-acyltransferase activity 1/279 25/18639 0.04 2.67225806451613 0.314282240560614 0.597250108411068 GO:0042974 nuclear retinoic acid receptor binding 1/279 25/18639 0.04 2.67225806451613 0.314282240560614 0.597250108411068 GO:0051536 iron-sulfur cluster binding 2/279 76/18639 0.0263157894736842 1.75806451612903 0.31518302550646 0.597250108411068 GO:0001216 DNA-binding transcription activator activity 9/279 491/18639 0.0183299389002037 1.22455817620393 0.315590823281498 0.597250108411068 GO:0003724 RNA helicase activity 2/279 77/18639 0.025974025974026 1.73523250942606 0.320689996733867 0.597250108411068 GO:0051540 metal cluster binding 2/279 77/18639 0.025974025974026 1.73523250942606 0.320689996733867 0.597250108411068 GO:0005112 Notch binding 1/279 26/18639 0.0384615384615385 2.56947890818859 0.324560270800411 0.597250108411068 GO:0005160 transforming growth factor beta receptor binding 1/279 26/18639 0.0384615384615385 2.56947890818859 0.324560270800411 0.597250108411068 GO:0008198 ferrous iron binding 1/279 26/18639 0.0384615384615385 2.56947890818859 0.324560270800411 0.597250108411068 GO:0019865 immunoglobulin binding 1/279 26/18639 0.0384615384615385 2.56947890818859 0.324560270800411 0.597250108411068 GO:0034237 protein kinase A regulatory subunit binding 1/279 26/18639 0.0384615384615385 2.56947890818859 0.324560270800411 0.597250108411068 GO:0043548 phosphatidylinositol 3-kinase binding 1/279 26/18639 0.0384615384615385 2.56947890818859 0.324560270800411 0.597250108411068 GO:0050681 nuclear androgen receptor binding 1/279 26/18639 0.0384615384615385 2.56947890818859 0.324560270800411 0.597250108411068 GO:0050750 low-density lipoprotein particle receptor binding 1/279 26/18639 0.0384615384615385 2.56947890818859 0.324560270800411 0.597250108411068 GO:0051087 protein-folding chaperone binding 3/279 134/18639 0.0223880597014925 1.49566682715455 0.324888495454881 0.597250108411068 GO:0008186 ATP-dependent activity, acting on RNA 2/279 79/18639 0.0253164556962025 1.69130257247856 0.331670626253755 0.602628918894988 GO:0016779 nucleotidyltransferase activity 3/279 136/18639 0.0220588235294118 1.47367172675522 0.333081787628988 0.602628918894988 GO:0019838 growth factor binding 3/279 136/18639 0.0220588235294118 1.47367172675522 0.333081787628988 0.602628918894988 GO:0001671 ATPase activator activity 1/279 27/18639 0.037037037037037 2.47431302270012 0.334684790461223 0.602628918894988 GO:0004364 glutathione transferase activity 1/279 27/18639 0.037037037037037 2.47431302270012 0.334684790461223 0.602628918894988 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/279 27/18639 0.037037037037037 2.47431302270012 0.334684790461223 0.602628918894988 GO:0005385 zinc ion transmembrane transporter activity 1/279 27/18639 0.037037037037037 2.47431302270012 0.334684790461223 0.602628918894988 GO:0019789 SUMO transferase activity 1/279 28/18639 0.0357142857142857 2.38594470046083 0.344658084221234 0.612871469411305 GO:0036408 histone H3K14 acetyltransferase activity 1/279 28/18639 0.0357142857142857 2.38594470046083 0.344658084221234 0.612871469411305 GO:0051393 alpha-actinin binding 1/279 28/18639 0.0357142857142857 2.38594470046083 0.344658084221234 0.612871469411305 GO:0051537 2 iron, 2 sulfur cluster binding 1/279 28/18639 0.0357142857142857 2.38594470046083 0.344658084221234 0.612871469411305 GO:0140101 catalytic activity, acting on a tRNA 3/279 139/18639 0.0215827338129496 1.44186586214899 0.345364052795296 0.612871469411305 GO:0016829 lyase activity 4/279 200/18639 0.02 1.33612903225806 0.351318800248094 0.616578457128815 GO:0004629 phospholipase C activity 1/279 29/18639 0.0344827586206897 2.30367074527252 0.35448240287699 0.616578457128815 GO:0010484 histone H3 acetyltransferase activity 1/279 29/18639 0.0344827586206897 2.30367074527252 0.35448240287699 0.616578457128815 GO:0016417 S-acyltransferase activity 1/279 29/18639 0.0344827586206897 2.30367074527252 0.35448240287699 0.616578457128815 GO:0043236 laminin binding 1/279 29/18639 0.0344827586206897 2.30367074527252 0.35448240287699 0.616578457128815 GO:0051861 glycolipid binding 1/279 29/18639 0.0344827586206897 2.30367074527252 0.35448240287699 0.616578457128815 GO:0106222 lncRNA binding 1/279 29/18639 0.0344827586206897 2.30367074527252 0.35448240287699 0.616578457128815 GO:0051117 ATPase binding 2/279 84/18639 0.0238095238095238 1.59062980030722 0.358887501258128 0.61937456454365 GO:0140098 catalytic activity, acting on RNA 7/279 387/18639 0.0180878552971576 1.20838542969076 0.359827434592328 0.61937456454365 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/279 30/18639 0.0333333333333333 2.22688172043011 0.364159963844068 0.61937456454365 GO:0031624 ubiquitin conjugating enzyme binding 1/279 30/18639 0.0333333333333333 2.22688172043011 0.364159963844068 0.61937456454365 GO:0043995 histone H4K5 acetyltransferase activity 1/279 30/18639 0.0333333333333333 2.22688172043011 0.364159963844068 0.61937456454365 GO:0043996 histone H4K8 acetyltransferase activity 1/279 30/18639 0.0333333333333333 2.22688172043011 0.364159963844068 0.61937456454365 GO:0043997 histone H4K12 acetyltransferase activity 1/279 30/18639 0.0333333333333333 2.22688172043011 0.364159963844068 0.61937456454365 GO:0051721 protein phosphatase 2A binding 1/279 30/18639 0.0333333333333333 2.22688172043011 0.364159963844068 0.61937456454365 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/279 31/18639 0.032258064516129 2.15504682622268 0.373692951650371 0.63208670058768 GO:0070325 lipoprotein particle receptor binding 1/279 31/18639 0.032258064516129 2.15504682622268 0.373692951650371 0.63208670058768 GO:0015106 bicarbonate transmembrane transporter activity 1/279 32/18639 0.03125 2.08770161290323 0.383083518422165 0.640908120738991 GO:0031369 translation initiation factor binding 1/279 32/18639 0.03125 2.08770161290323 0.383083518422165 0.640908120738991 GO:0042910 xenobiotic transmembrane transporter activity 1/279 32/18639 0.03125 2.08770161290323 0.383083518422165 0.640908120738991 GO:0043425 bHLH transcription factor binding 1/279 32/18639 0.03125 2.08770161290323 0.383083518422165 0.640908120738991 GO:0008094 ATP-dependent activity, acting on DNA 4/279 210/18639 0.019047619047619 1.27250384024578 0.38526222044035 0.642801639539062 GO:0019210 kinase inhibitor activity 2/279 90/18639 0.0222222222222222 1.48458781362007 0.390995144904715 0.645825586055905 GO:0019001 guanyl nucleotide binding 7/279 400/18639 0.0175 1.16911290322581 0.391607651014737 0.645825586055905 GO:0032561 guanyl ribonucleotide binding 7/279 400/18639 0.0175 1.16911290322581 0.391607651014737 0.645825586055905 GO:0042923 neuropeptide binding 1/279 33/18639 0.0303030303030303 2.02443792766373 0.392333784362952 0.645825586055905 GO:0071889 14-3-3 protein binding 1/279 33/18639 0.0303030303030303 2.02443792766373 0.392333784362952 0.645825586055905 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/279 91/18639 0.021978021978022 1.46827366182205 0.396278285926458 0.650574512189426 GO:0015035 protein-disulfide reductase activity 1/279 34/18639 0.0294117647058824 1.96489563567362 0.401445838225294 0.6538136463404 GO:0019825 oxygen binding 1/279 34/18639 0.0294117647058824 1.96489563567362 0.401445838225294 0.6538136463404 GO:0030332 cyclin binding 1/279 34/18639 0.0294117647058824 1.96489563567362 0.401445838225294 0.6538136463404 GO:0051219 phosphoprotein binding 2/279 93/18639 0.021505376344086 1.43669788414846 0.406780790718567 0.659683107314855 GO:0030246 carbohydrate binding 5/279 280/18639 0.0178571428571429 1.19297235023041 0.409000971055301 0.659683107314855 GO:0004386 helicase activity 3/279 155/18639 0.0193548387096774 1.29302809573361 0.410269029727617 0.659683107314855 GO:0010485 histone H4 acetyltransferase activity 1/279 35/18639 0.0285714285714286 1.90875576036866 0.410421737775691 0.659683107314855 GO:0061631 ubiquitin conjugating enzyme activity 1/279 35/18639 0.0285714285714286 1.90875576036866 0.410421737775691 0.659683107314855 GO:0042562 hormone binding 2/279 94/18639 0.0212765957446809 1.42141386410432 0.411999069397424 0.660489369738951 GO:0008276 protein methyltransferase activity 2/279 95/18639 0.0210526315789474 1.40645161290323 0.417194676943789 0.661768111298463 GO:0000993 RNA polymerase II complex binding 1/279 36/18639 0.0277777777777778 1.85573476702509 0.419263510252609 0.661768111298463 GO:0004033 aldo-keto reductase (NADPH) activity 1/279 36/18639 0.0277777777777778 1.85573476702509 0.419263510252609 0.661768111298463 GO:0004190 aspartic-type endopeptidase activity 1/279 36/18639 0.0277777777777778 1.85573476702509 0.419263510252609 0.661768111298463 GO:0016409 palmitoyltransferase activity 1/279 36/18639 0.0277777777777778 1.85573476702509 0.419263510252609 0.661768111298463 GO:0055106 ubiquitin-protein transferase regulator activity 1/279 36/18639 0.0277777777777778 1.85573476702509 0.419263510252609 0.661768111298463 GO:0042805 actinin binding 1/279 37/18639 0.027027027027027 1.80557977332171 0.427973152817761 0.672060142787994 GO:0070001 aspartic-type peptidase activity 1/279 37/18639 0.027027027027027 1.80557977332171 0.427973152817761 0.672060142787994 GO:0000146 microfilament motor activity 1/279 38/18639 0.0263157894736842 1.75806451612903 0.436552633000744 0.681319342057106 GO:0043531 ADP binding 1/279 38/18639 0.0263157894736842 1.75806451612903 0.436552633000744 0.681319342057106 GO:0141003 histone H2AX kinase activity 6/279 354/18639 0.0169491525423729 1.13231273920175 0.43719840516368 0.681319342057106 GO:0000217 DNA secondary structure binding 1/279 39/18639 0.0256410256410256 1.71298593879239 0.445003889137124 0.68796990638029 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/279 39/18639 0.0256410256410256 1.71298593879239 0.445003889137124 0.68796990638029 GO:0140996 histone H3 kinase activity 6/279 357/18639 0.0168067226890756 1.12279750609921 0.445137125904344 0.68796990638029 GO:0140713 histone chaperone activity 3/279 164/18639 0.0182926829268293 1.2220692368214 0.445947919770937 0.68796990638029 GO:0005085 guanyl-nucleotide exchange factor activity 4/279 230/18639 0.0173913043478261 1.16185133239832 0.45227795531056 0.688970054730794 GO:0035173 histone kinase activity 6/279 360/18639 0.0166666666666667 1.11344086021505 0.453053477807015 0.688970054730794 GO:0015036 disulfide oxidoreductase activity 1/279 40/18639 0.025 1.67016129032258 0.453328830800067 0.688970054730794 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/279 40/18639 0.025 1.67016129032258 0.453328830800067 0.688970054730794 GO:0061791 GTPase motor activity 1/279 40/18639 0.025 1.67016129032258 0.453328830800067 0.688970054730794 GO:1990606 membrane scission GTPase motor activity 1/279 40/18639 0.025 1.67016129032258 0.453328830800067 0.688970054730794 GO:0001530 lipopolysaccharide binding 1/279 41/18639 0.024390243902439 1.6294256490952 0.461529339225615 0.696262934360019 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/279 41/18639 0.024390243902439 1.6294256490952 0.461529339225615 0.696262934360019 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/279 41/18639 0.024390243902439 1.6294256490952 0.461529339225615 0.696262934360019 GO:0016755 aminoacyltransferase activity 8/279 496/18639 0.0161290322580645 1.07752341311134 0.465551679512021 0.700609635344071 GO:0004402 histone acetyltransferase activity 1/279 42/18639 0.0238095238095238 1.59062980030722 0.469607267731694 0.703265518017708 GO:0035198 miRNA binding 1/279 42/18639 0.0238095238095238 1.59062980030722 0.469607267731694 0.703265518017708 GO:0000149 SNARE binding 2/279 106/18639 0.0188679245283019 1.26049908703591 0.472723050757774 0.704495031954547 GO:0008013 beta-catenin binding 2/279 106/18639 0.0188679245283019 1.26049908703591 0.472723050757774 0.704495031954547 GO:0046982 protein heterodimerization activity 6/279 369/18639 0.016260162601626 1.08628376606347 0.476640704250538 0.704866748722115 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/279 43/18639 0.0232558139534884 1.5536384096024 0.477564442130944 0.704866748722115 GO:0008200 ion channel inhibitor activity 1/279 43/18639 0.0232558139534884 1.5536384096024 0.477564442130944 0.704866748722115 GO:0008375 acetylglucosaminyltransferase activity 1/279 43/18639 0.0232558139534884 1.5536384096024 0.477564442130944 0.704866748722115 GO:0140030 modification-dependent protein binding 3/279 173/18639 0.0173410404624277 1.15849338057058 0.480747029323325 0.707862532384944 GO:0001046 core promoter sequence-specific DNA binding 1/279 44/18639 0.0227272727272727 1.5183284457478 0.485402661137476 0.707926921468908 GO:0001223 transcription coactivator binding 1/279 44/18639 0.0227272727272727 1.5183284457478 0.485402661137476 0.707926921468908 GO:0016248 channel inhibitor activity 1/279 44/18639 0.0227272727272727 1.5183284457478 0.485402661137476 0.707926921468908 GO:0043014 alpha-tubulin binding 1/279 44/18639 0.0227272727272727 1.5183284457478 0.485402661137476 0.707926921468908 GO:0046915 transition metal ion transmembrane transporter activity 1/279 45/18639 0.0222222222222222 1.48458781362007 0.493123696767627 0.714098938243686 GO:0051539 4 iron, 4 sulfur cluster binding 1/279 45/18639 0.0222222222222222 1.48458781362007 0.493123696767627 0.714098938243686 GO:0141110 transporter inhibitor activity 1/279 45/18639 0.0222222222222222 1.48458781362007 0.493123696767627 0.714098938243686 GO:0005319 lipid transporter activity 3/279 178/18639 0.0168539325842697 1.12595143167814 0.499633284583695 0.718215900435005 GO:0030291 protein serine/threonine kinase inhibitor activity 1/279 46/18639 0.0217391304347826 1.4523141654979 0.500729294734811 0.718215900435005 GO:0016853 isomerase activity 3/279 180/18639 0.0166666666666667 1.11344086021505 0.507090555765872 0.718215900435005 GO:0061733 protein-lysine-acetyltransferase activity 1/279 47/18639 0.0212765957446809 1.42141386410432 0.508221174838559 0.718215900435005 GO:0140359 ABC-type transporter activity 1/279 47/18639 0.0212765957446809 1.42141386410432 0.508221174838559 0.718215900435005 GO:0140938 histone H3 methyltransferase activity 1/279 47/18639 0.0212765957446809 1.42141386410432 0.508221174838559 0.718215900435005 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/279 47/18639 0.0212765957446809 1.42141386410432 0.508221174838559 0.718215900435005 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/279 48/18639 0.0208333333333333 1.39180107526882 0.515601031347813 0.718215900435005 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/279 48/18639 0.0208333333333333 1.39180107526882 0.515601031347813 0.718215900435005 GO:0038187 pattern recognition receptor activity 1/279 48/18639 0.0208333333333333 1.39180107526882 0.515601031347813 0.718215900435005 GO:0043138 3'-5' DNA helicase activity 1/279 48/18639 0.0208333333333333 1.39180107526882 0.515601031347813 0.718215900435005 GO:0001221 transcription coregulator binding 2/279 115/18639 0.0173913043478261 1.16185133239832 0.515721490390083 0.718215900435005 GO:0005004 GPI-linked ephrin receptor activity 1/279 49/18639 0.0204081632653061 1.3633969716919 0.522870533378578 0.718215900435005 GO:0005008 hepatocyte growth factor receptor activity 1/279 49/18639 0.0204081632653061 1.3633969716919 0.522870533378578 0.718215900435005 GO:0005009 insulin receptor activity 1/279 49/18639 0.0204081632653061 1.3633969716919 0.522870533378578 0.718215900435005 GO:0005011 macrophage colony-stimulating factor receptor activity 1/279 49/18639 0.0204081632653061 1.3633969716919 0.522870533378578 0.718215900435005 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/279 49/18639 0.0204081632653061 1.3633969716919 0.522870533378578 0.718215900435005 GO:0005020 stem cell factor receptor activity 1/279 49/18639 0.0204081632653061 1.3633969716919 0.522870533378578 0.718215900435005 GO:0008288 boss receptor activity 1/279 49/18639 0.0204081632653061 1.3633969716919 0.522870533378578 0.718215900435005 GO:0036332 placental growth factor receptor activity 1/279 49/18639 0.0204081632653061 1.3633969716919 0.522870533378578 0.718215900435005 GO:0038062 protein tyrosine kinase collagen receptor activity 1/279 49/18639 0.0204081632653061 1.3633969716919 0.522870533378578 0.718215900435005 GO:0060175 brain-derived neurotrophic factor receptor activity 1/279 49/18639 0.0204081632653061 1.3633969716919 0.522870533378578 0.718215900435005 GO:0060590 ATPase regulator activity 1/279 49/18639 0.0204081632653061 1.3633969716919 0.522870533378578 0.718215900435005 GO:1990782 protein tyrosine kinase binding 2/279 117/18639 0.0170940170940171 1.14199062586159 0.524958091255625 0.719473812569093 GO:0005006 epidermal growth factor receptor activity 1/279 50/18639 0.02 1.33612903225806 0.530031325266011 0.719998304675511 GO:0005007 fibroblast growth factor receptor activity 1/279 50/18639 0.02 1.33612903225806 0.530031325266011 0.719998304675511 GO:0005017 platelet-derived growth factor receptor activity 1/279 50/18639 0.02 1.33612903225806 0.530031325266011 0.719998304675511 GO:0005019 platelet-derived growth factor beta-receptor activity 1/279 50/18639 0.02 1.33612903225806 0.530031325266011 0.719998304675511 GO:0005010 insulin-like growth factor receptor activity 1/279 51/18639 0.0196078431372549 1.30993042378242 0.537085026931016 0.72428007899771 GO:0005021 vascular endothelial growth factor receptor activity 1/279 51/18639 0.0196078431372549 1.30993042378242 0.537085026931016 0.72428007899771 GO:0005030 neurotrophin receptor activity 1/279 51/18639 0.0196078431372549 1.30993042378242 0.537085026931016 0.72428007899771 GO:0032182 ubiquitin-like protein binding 2/279 120/18639 0.0166666666666667 1.11344086021505 0.538589504065535 0.72428007899771 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/279 52/18639 0.0192307692307692 1.28473945409429 0.544033234241445 0.72428007899771 GO:0030159 signaling receptor complex adaptor activity 1/279 52/18639 0.0192307692307692 1.28473945409429 0.544033234241445 0.72428007899771 GO:0008528 G protein-coupled peptide receptor activity 2/279 122/18639 0.0163934426229508 1.09518773135907 0.54752657282794 0.72428007899771 GO:0004864 protein phosphatase inhibitor activity 1/279 53/18639 0.0188679245283019 1.26049908703591 0.550877519367965 0.72428007899771 GO:0005003 ephrin receptor activity 1/279 53/18639 0.0188679245283019 1.26049908703591 0.550877519367965 0.72428007899771 GO:0005005 transmembrane-ephrin receptor activity 1/279 53/18639 0.0188679245283019 1.26049908703591 0.550877519367965 0.72428007899771 GO:0005246 calcium channel regulator activity 1/279 53/18639 0.0188679245283019 1.26049908703591 0.550877519367965 0.72428007899771 GO:0005544 calcium-dependent phospholipid binding 1/279 53/18639 0.0188679245283019 1.26049908703591 0.550877519367965 0.72428007899771 GO:0017046 peptide hormone binding 1/279 53/18639 0.0188679245283019 1.26049908703591 0.550877519367965 0.72428007899771 GO:0034212 protein N-acetyltransferase activity 1/279 53/18639 0.0188679245283019 1.26049908703591 0.550877519367965 0.72428007899771 GO:0038064 collagen receptor activity 1/279 53/18639 0.0188679245283019 1.26049908703591 0.550877519367965 0.72428007899771 GO:0003925 G protein activity 1/279 54/18639 0.0185185185185185 1.23715651135006 0.55761943113469 0.731577629736538 GO:0140097 catalytic activity, acting on DNA 5/279 336/18639 0.0148809523809524 0.994143625192012 0.567637972808429 0.743133721331291 GO:0019212 phosphatase inhibitor activity 1/279 56/18639 0.0178571428571429 1.19297235023041 0.570802215220057 0.745686298181095 GO:0001653 peptide receptor activity 2/279 128/18639 0.015625 1.04385080645161 0.573606439910808 0.747758713599227 GO:0019787 ubiquitin-like protein transferase activity 7/279 479/18639 0.0146137787056367 0.976294699979796 0.578779989366409 0.752904477692744 GO:0005096 GTPase activator activity 4/279 271/18639 0.014760147601476 0.986073086537317 0.580504227060621 0.753550941681229 GO:0017116 single-stranded DNA helicase activity 1/279 58/18639 0.0172413793103448 1.15183537263626 0.583593523159903 0.755962918186035 GO:0031593 polyubiquitin modification-dependent protein binding 1/279 59/18639 0.0169491525423729 1.13231273920175 0.589846007258627 0.758352181293075 GO:0036002 pre-mRNA binding 1/279 59/18639 0.0169491525423729 1.13231273920175 0.589846007258627 0.758352181293075 GO:0070888 E-box binding 1/279 59/18639 0.0169491525423729 1.13231273920175 0.589846007258627 0.758352181293075 GO:0005179 hormone activity 2/279 132/18639 0.0151515151515152 1.01221896383187 0.590378408237931 0.758352181293075 GO:0001098 basal transcription machinery binding 1/279 60/18639 0.0166666666666667 1.11344086021505 0.596004939657704 0.758432081803331 GO:0001099 basal RNA polymerase II transcription machinery binding 1/279 60/18639 0.0166666666666667 1.11344086021505 0.596004939657704 0.758432081803331 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/279 60/18639 0.0166666666666667 1.11344086021505 0.596004939657704 0.758432081803331 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/279 60/18639 0.0166666666666667 1.11344086021505 0.596004939657704 0.758432081803331 GO:0030695 GTPase regulator activity 7/279 489/18639 0.0143149284253579 0.956329573190844 0.600639001165679 0.758432081803331 GO:0005516 calmodulin binding 3/279 207/18639 0.0144927536231884 0.968209443665264 0.601627817029109 0.758432081803331 GO:0015026 coreceptor activity 1/279 61/18639 0.0163934426229508 1.09518773135907 0.602071715148069 0.758432081803331 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/279 61/18639 0.0163934426229508 1.09518773135907 0.602071715148069 0.758432081803331 GO:0019905 syntaxin binding 1/279 61/18639 0.0163934426229508 1.09518773135907 0.602071715148069 0.758432081803331 GO:0060589 nucleoside-triphosphatase regulator activity 7/279 490/18639 0.0142857142857143 0.954377880184332 0.602792924951182 0.758432081803331 GO:0015179 L-amino acid transmembrane transporter activity 1/279 62/18639 0.0161290322580645 1.07752341311134 0.608047707799253 0.763479125948346 GO:0005507 copper ion binding 1/279 63/18639 0.0158730158730159 1.06041986687148 0.613934271266121 0.769297229708976 GO:0035091 phosphatidylinositol binding 4/279 284/18639 0.0140845070422535 0.940935938209905 0.617453475486933 0.771918650712368 GO:0140767 enzyme-substrate adaptor activity 2/279 139/18639 0.0143884892086331 0.961243908099327 0.618540677769519 0.771918650712368 GO:0019207 kinase regulator activity 4/279 287/18639 0.0139372822299652 0.931100370911543 0.625687965515288 0.779254383014983 GO:0016500 protein-hormone receptor activity 1/279 67/18639 0.0149253731343284 0.997111218103033 0.636612608674568 0.789656851972091 GO:0042054 histone methyltransferase activity 1/279 67/18639 0.0149253731343284 0.997111218103033 0.636612608674568 0.789656851972091 GO:0030145 manganese ion binding 1/279 68/18639 0.0147058823529412 0.982447817836812 0.642071637437211 0.794822551182354 GO:0016279 protein-lysine N-methyltransferase activity 1/279 69/18639 0.0144927536231884 0.968209443665264 0.647448946852698 0.799866505769732 GO:0016278 lysine N-methyltransferase activity 1/279 70/18639 0.0142857142857143 0.954377880184332 0.652745755890291 0.804790952041443 GO:0061659 ubiquitin-like protein ligase activity 5/279 372/18639 0.0134408602150538 0.897936177592785 0.657249084066312 0.80622043227083 GO:0000510 H3-H4 histone complex chaperone activity 2/279 151/18639 0.0132450331125828 0.884853663747063 0.663320442543948 0.80622043227083 GO:0140584 chromatin extrusion motor activity 2/279 151/18639 0.0132450331125828 0.884853663747063 0.663320442543948 0.80622043227083 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/279 151/18639 0.0132450331125828 0.884853663747063 0.663320442543948 0.80622043227083 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/279 151/18639 0.0132450331125828 0.884853663747063 0.663320442543948 0.80622043227083 GO:0015616 DNA translocase activity 2/279 152/18639 0.0131578947368421 0.879032258064516 0.666855159582449 0.80622043227083 GO:0140674 ATP-dependent histone chaperone activity 2/279 152/18639 0.0131578947368421 0.879032258064516 0.666855159582449 0.80622043227083 GO:0004842 ubiquitin-protein transferase activity 6/279 449/18639 0.0133630289532294 0.892736547165745 0.666913430172496 0.80622043227083 GO:0004521 RNA endonuclease activity 1/279 73/18639 0.0136986301369863 0.915156871409633 0.668165100262448 0.80622043227083 GO:0043539 protein serine/threonine kinase activator activity 1/279 73/18639 0.0136986301369863 0.915156871409633 0.668165100262448 0.80622043227083 GO:0003774 cytoskeletal motor activity 2/279 153/18639 0.0130718954248366 0.873286949188278 0.670359972158892 0.80622043227083 GO:0061775 cohesin loader activity 2/279 153/18639 0.0130718954248366 0.873286949188278 0.670359972158892 0.80622043227083 GO:0005525 GTP binding 5/279 378/18639 0.0132275132275132 0.8836832223929 0.670974985163508 0.80622043227083 GO:0035064 methylated histone binding 1/279 74/18639 0.0135135135135135 0.902789886660854 0.673151739119864 0.806500346430522 GO:0005506 iron ion binding 2/279 154/18639 0.012987012987013 0.867616254713029 0.67383497999814 0.806500346430522 GO:0140034 methylation-dependent protein binding 1/279 76/18639 0.0131578947368421 0.879032258064516 0.682902115054462 0.815762448722645 GO:0140658 ATP-dependent chromatin remodeler activity 2/279 158/18639 0.0126582278481013 0.845651286239281 0.687439085657042 0.819473701196411 GO:0019199 transmembrane receptor protein kinase activity 1/279 78/18639 0.0128205128205128 0.856492969396195 0.692362634077225 0.819473701196411 GO:0003689 DNA clamp loader activity 2/279 160/18639 0.0125 0.83508064516129 0.69406516347754 0.819473701196411 GO:0008083 growth factor activity 2/279 162/18639 0.0123456790123457 0.824771007566706 0.700575204451126 0.819473701196411 GO:0000049 tRNA binding 1/279 80/18639 0.0125 0.83508064516129 0.701541882911382 0.819473701196411 GO:0048306 calcium-dependent protein binding 1/279 80/18639 0.0125 0.83508064516129 0.701541882911382 0.819473701196411 GO:0030971 receptor tyrosine kinase binding 1/279 81/18639 0.0123456790123457 0.824771007566706 0.706028644841859 0.819473701196411 GO:0033192 calmodulin-dependent protein phosphatase activity 1/279 81/18639 0.0123456790123457 0.824771007566706 0.706028644841859 0.819473701196411 GO:0140791 histone H2AXS140 phosphatase activity 1/279 81/18639 0.0123456790123457 0.824771007566706 0.706028644841859 0.819473701196411 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/279 81/18639 0.0123456790123457 0.824771007566706 0.706028644841859 0.819473701196411 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/279 81/18639 0.0123456790123457 0.824771007566706 0.706028644841859 0.819473701196411 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/279 81/18639 0.0123456790123457 0.824771007566706 0.706028644841859 0.819473701196411 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/279 81/18639 0.0123456790123457 0.824771007566706 0.706028644841859 0.819473701196411 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/279 81/18639 0.0123456790123457 0.824771007566706 0.706028644841859 0.819473701196411 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/279 81/18639 0.0123456790123457 0.824771007566706 0.706028644841859 0.819473701196411 GO:0015103 inorganic anion transmembrane transporter activity 2/279 165/18639 0.0121212121212121 0.809775171065494 0.7101249347958 0.819953367680588 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/279 82/18639 0.0121951219512195 0.8147128245476 0.710448194798164 0.819953367680588 GO:0033549 MAP kinase phosphatase activity 1/279 82/18639 0.0121951219512195 0.8147128245476 0.710448194798164 0.819953367680588 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/279 83/18639 0.0120481927710843 0.804897007384376 0.71480153605221 0.821887908494488 GO:0030165 PDZ domain binding 1/279 83/18639 0.0120481927710843 0.804897007384376 0.71480153605221 0.821887908494488 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/279 167/18639 0.0119760479041916 0.800077264825188 0.716349427446852 0.82212812794835 GO:0004860 protein kinase inhibitor activity 1/279 84/18639 0.0119047619047619 0.79531490015361 0.719089656953343 0.822199347056523 GO:0017018 myosin phosphatase activity 1/279 84/18639 0.0119047619047619 0.79531490015361 0.719089656953343 0.822199347056523 GO:0008081 phosphoric diester hydrolase activity 1/279 87/18639 0.0114942528735632 0.767890248424175 0.731572361815986 0.834917156421961 GO:0003924 GTPase activity 4/279 331/18639 0.0120845921450151 0.807328720397622 0.733144715149902 0.835159285903598 GO:0052689 carboxylic ester hydrolase activity 1/279 92/18639 0.0108695652173913 0.726157082748948 0.751160541116301 0.854097356010017 GO:0051213 dioxygenase activity 1/279 93/18639 0.010752688172043 0.718348942074228 0.754903799272798 0.856766973666355 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 3/279 268/18639 0.0111940298507463 0.747833413577275 0.767908159941021 0.869040540420593 GO:0008514 organic anion transmembrane transporter activity 3/279 269/18639 0.0111524163568773 0.745053363712675 0.770087844897021 0.869040540420593 GO:0008170 N-methyltransferase activity 1/279 98/18639 0.0102040816326531 0.681698485845951 0.772795008256749 0.869040540420593 GO:0030527 structural constituent of chromatin 1/279 98/18639 0.0102040816326531 0.681698485845951 0.772795008256749 0.869040540420593 GO:0042626 ATPase-coupled transmembrane transporter activity 1/279 98/18639 0.0102040816326531 0.681698485845951 0.772795008256749 0.869040540420593 GO:0061630 ubiquitin protein ligase activity 4/279 353/18639 0.0113314447592068 0.757013616010235 0.777448131758354 0.87267486818945 GO:0015171 amino acid transmembrane transporter activity 1/279 102/18639 0.00980392156862745 0.654965211891208 0.78616614797973 0.880850392079478 GO:0001217 DNA-binding transcription repressor activity 3/279 278/18639 0.0107913669064748 0.720932931074495 0.788963115949534 0.881240214343376 GO:0004722 protein serine/threonine phosphatase activity 1/279 103/18639 0.00970873786407767 0.648606326338866 0.789384556822242 0.881240214343376 GO:0004620 phospholipase activity 1/279 109/18639 0.00917431192660551 0.612903225806452 0.807706232188903 0.900057398482734 GO:0008168 methyltransferase activity 2/279 204/18639 0.00980392156862745 0.654965211891208 0.812557529545189 0.903823049168019 GO:0015294 solute:monoatomic cation symporter activity 1/279 116/18639 0.00862068965517241 0.575917686318131 0.827083512966533 0.918316956530653 GO:0016741 transferase activity, transferring one-carbon groups 2/279 215/18639 0.00930232558139535 0.62145536384096 0.834956572792941 0.925385082481707 GO:0004540 RNA nuclease activity 1/279 121/18639 0.00826446280991736 0.552119434817382 0.839721045117887 0.926407652845978 GO:0015108 chloride transmembrane transporter activity 1/279 121/18639 0.00826446280991736 0.552119434817382 0.839721045117887 0.926407652845978 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/279 122/18639 0.00819672131147541 0.547593865679535 0.842135875467391 0.926407652845978 GO:0004519 endonuclease activity 1/279 127/18639 0.0078740157480315 0.526035052070104 0.85367693791137 0.926407652845978 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/279 128/18639 0.0078125 0.521925403225806 0.855882217423186 0.926407652845978 GO:0016298 lipase activity 1/279 130/18639 0.00769230769230769 0.513895781637717 0.860193914763176 0.926407652845978 GO:0015297 antiporter activity 1/279 135/18639 0.00740740740740741 0.494862604540024 0.87041908282034 0.926407652845978 GO:0140789 histone phosphatase activity 1/279 136/18639 0.00735294117647059 0.491223908918406 0.872372880696104 0.926407652845978 GO:0030295 protein kinase activator activity 1/279 139/18639 0.00719424460431655 0.480621954049664 0.878059895625076 0.926407652845978 GO:0070851 growth factor receptor binding 1/279 139/18639 0.00719424460431655 0.480621954049664 0.878059895625076 0.926407652845978 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 2/279 243/18639 0.00823045267489712 0.549847338377804 0.881471528228775 0.926407652845978 GO:0020037 heme binding 1/279 142/18639 0.00704225352112676 0.470467969104952 0.883494367190863 0.926407652845978 GO:0004676 3-phosphoinositide-dependent protein kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0004711 ribosomal protein S6 kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0035175 histone H3S10 kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0035979 histone H2AXS139 kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0044022 histone H3S28 kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0044023 histone H4S1 kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0044024 histone H2AS1 kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0044025 histone H2BS14 kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0072354 histone H3T3 kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0072371 histone H2AS121 kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0072518 Rho-dependent protein serine/threonine kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0140823 histone H2BS36 kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0140855 histone H3S57 kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0140995 histone H2A kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0140997 histone H4 kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0140998 histone H2B kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:1990244 histone H2AT120 kinase activity 2/279 245/18639 0.00816326530612245 0.545358788676761 0.884282906047168 0.926407652845978 GO:0004677 DNA-dependent protein kinase activity 2/279 246/18639 0.00813008130081301 0.543141883031734 0.88566540858908 0.926407652845978 GO:0140857 histone H3T45 kinase activity 2/279 246/18639 0.00813008130081301 0.543141883031734 0.88566540858908 0.926407652845978 GO:0035402 histone H3T11 kinase activity 2/279 247/18639 0.00809716599190283 0.540942928039702 0.887032648421474 0.926407652845978 GO:0035403 histone H3T6 kinase activity 2/279 247/18639 0.00809716599190283 0.540942928039702 0.887032648421474 0.926407652845978 GO:0004679 AMP-activated protein kinase activity 2/279 248/18639 0.00806451612903226 0.538761706555671 0.888384770575651 0.926407652845978 GO:0008194 UDP-glycosyltransferase activity 1/279 145/18639 0.00689655172413793 0.460734149054505 0.888687471541174 0.926407652845978 GO:0015293 symporter activity 1/279 146/18639 0.00684931506849315 0.457578435704817 0.890366729432383 0.92658503707031 GO:0019209 kinase activator activity 1/279 148/18639 0.00675675675675676 0.451394943330427 0.893649891936856 0.92765510080446 GO:0008509 monoatomic anion transmembrane transporter activity 1/279 149/18639 0.00671140939597315 0.448365447066465 0.89525454718263 0.92765510080446 GO:0019842 vitamin binding 1/279 150/18639 0.00666666666666667 0.445376344086022 0.896835076189447 0.92765510080446 GO:0019887 protein kinase regulator activity 2/279 255/18639 0.00784313725490196 0.523972169512966 0.897438322276627 0.92765510080446 GO:0046906 tetrapyrrole binding 1/279 152/18639 0.00657894736842105 0.439516129032258 0.899925195915944 0.92866230301242 GO:0106310 protein serine kinase activity 3/279 361/18639 0.00831024930747922 0.555178268251273 0.909314073028108 0.9357753606647 GO:0042578 phosphoric ester hydrolase activity 3/279 363/18639 0.00826446280991736 0.552119434817382 0.911234988863884 0.9357753606647 GO:0099106 ion channel regulator activity 1/279 160/18639 0.00625 0.417540322580645 0.911390334979627 0.9357753606647 GO:0016791 phosphatase activity 2/279 273/18639 0.00732600732600733 0.489424553940683 0.91767988341032 0.940660180991547 GO:0008017 microtubule binding 2/279 276/18639 0.0072463768115942 0.484104721832632 0.920666123289908 0.941479737755956 GO:0016247 channel regulator activity 1/279 168/18639 0.00595238095238095 0.397657450076805 0.921546127673175 0.941479737755956 GO:0141108 transporter regulator activity 1/279 170/18639 0.00588235294117647 0.392979127134725 0.923898344957905 0.942314923262714 GO:0004721 phosphoprotein phosphatase activity 1/279 175/18639 0.00571428571428571 0.381751152073733 0.929475976197577 0.94461377753669 GO:0015631 tubulin binding 3/279 385/18639 0.00779220779220779 0.520569752827817 0.930058094442407 0.94461377753669 GO:0015291 secondary active transmembrane transporter activity 2/279 287/18639 0.00696864111498258 0.465550185455772 0.930767647247064 0.94461377753669 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/279 181/18639 0.00552486187845304 0.369096417750847 0.935633965644162 0.947985569151016 GO:0046943 carboxylic acid transmembrane transporter activity 1/279 188/18639 0.00531914893617021 0.355353466026081 0.942144239899497 0.952325193850618 GO:0005342 organic acid transmembrane transporter activity 1/279 189/18639 0.00529100529100529 0.35347328895716 0.943019084464455 0.952325193850618 GO:0016758 hexosyltransferase activity 1/279 197/18639 0.0050761421319797 0.339119043720321 0.949559548715473 0.957355604123646 GO:0004518 nuclease activity 1/279 209/18639 0.00478468899521531 0.319648093841642 0.95799414180517 0.96380372166683 GO:0004674 protein serine/threonine kinase activity 3/279 433/18639 0.0069284064665127 0.462862251359607 0.959094582961617 0.96380372166683 GO:0016757 glycosyltransferase activity 1/279 267/18639 0.00374531835205993 0.25021142926181 0.982682997539588 0.985894379884488 GO:0005216 monoatomic ion channel activity 1/279 448/18639 0.00223214285714286 0.149121543778802 0.998929477730175 0.99896206454393 GO:0046873 metal ion transmembrane transporter activity 1/279 450/18639 0.00222222222222222 0.148458781362007 0.99896206454393 0.99896206454393