ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0042605	peptide antigen binding	20/1249	45/18639	0.444444444444444	6.63250600480384	1.81075920728774e-12	2.02623955295498e-09
GO:0023026	MHC class II protein complex binding	13/1249	27/18639	0.481481481481481	7.1852148385375	4.27364977126809e-09	2.3911070470245e-06
GO:0042277	peptide binding	43/1249	249/18639	0.172690763052209	2.57708817656535	8.84850998066885e-09	3.30049422278948e-06
GO:0140297	DNA-binding transcription factor binding	67/1249	488/18639	0.137295081967213	2.04887352504955	1.56104705465565e-08	4.36702913539919e-06
GO:0023023	MHC protein complex binding	14/1249	37/18639	0.378378378378378	5.6465929500357	4.8517731794203e-08	1.08582683755426e-05
GO:0031072	heat shock protein binding	27/1249	131/18639	0.206106870229008	3.07576137245674	1.32756365964391e-07	2.47590622523588e-05
GO:0051082	unfolded protein binding	25/1249	121/18639	0.206611570247934	3.08329308074559	3.6507810256186e-07	5.21196620984957e-05
GO:0044389	ubiquitin-like protein ligase binding	47/1249	322/18639	0.145962732919255	2.17822208077021	3.72615993554929e-07	5.21196620984957e-05
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	7/1249	10/18639	0.7	10.4461969575661	5.98564276820779e-07	7.44214917513835e-05
GO:0031625	ubiquitin protein ligase binding	44/1249	302/18639	0.145695364238411	2.17423210091252	9.17297134299023e-07	0.000102645549328061
GO:0044183	protein folding chaperone	18/1249	75/18639	0.24	3.58155324259408	1.61238386940479e-06	0.000164023413623996
GO:0060590	ATPase regulator activity	14/1249	49/18639	0.285714285714286	4.26375386023104	2.50788391570044e-06	0.000233860175139066
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	47/1249	349/18639	0.134670487106017	2.00970633240116	3.72798048068001e-06	0.000320893089067764
GO:0038024	cargo receptor activity	16/1249	65/18639	0.246153846153846	3.67338794112213	4.25207916997632e-06	0.000339862613657393
GO:0030169	low-density lipoprotein particle binding	8/1249	17/18639	0.470588235294118	7.02265341685113	5.59740941482832e-06	0.000417566742346193
GO:0001221	transcription coregulator binding	22/1249	115/18639	0.191304347826087	2.85486128032861	6.82942432504391e-06	0.000469561834924226
GO:0140662	ATP-dependent protein folding chaperone	12/1249	40/18639	0.3	4.47694155324259	7.48268627070414e-06	0.000469561834924226
GO:0008135	translation factor activity, RNA binding	18/1249	83/18639	0.216867469879518	3.23634329150067	7.55327348403581e-06	0.000469561834924226
GO:0180051	translation factor activity	18/1249	84/18639	0.214285714285714	3.19781539517328	9.01821068748979e-06	0.000530570241466127
GO:0003746	translation elongation factor activity	8/1249	18/18639	0.444444444444444	6.63250600480384	9.48293550430968e-06	0.000530570241466127
GO:0042826	histone deacetylase binding	23/1249	127/18639	0.181102362204724	2.70261563581574	1.10143537208181e-05	0.000586907705409306
GO:0045296	cadherin binding	43/1249	334/18639	0.12874251497006	1.92124238312806	2.89749614207953e-05	0.00132568829849024
GO:0071813	lipoprotein particle binding	10/1249	32/18639	0.3125	4.6634807846277	2.90988554342696e-05	0.00132568829849024
GO:0071814	protein-lipid complex binding	10/1249	32/18639	0.3125	4.6634807846277	2.90988554342696e-05	0.00132568829849024
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	17/1249	83/18639	0.204819277108434	3.05654644197286	2.96177010386559e-05	0.00132568829849024
GO:0140311	protein sequestering activity	10/1249	33/18639	0.303030303030303	4.52216318509353	3.9256304661975e-05	0.00162695573765741
GO:0140416	transcription regulator inhibitor activity	10/1249	33/18639	0.303030303030303	4.52216318509353	3.9256304661975e-05	0.00162695573765741
GO:0001671	ATPase activator activity	9/1249	27/18639	0.333333333333333	4.97437950360288	4.11339170662124e-05	0.00164388761418185
GO:0140597	protein carrier chaperone	28/1249	188/18639	0.148936170212766	2.22259509735448	5.67731840177674e-05	0.00219066182468558
GO:0033192	calmodulin-dependent protein phosphatase activity	16/1249	81/18639	0.197530864197531	2.94778044657949	7.98427003703061e-05	0.00236664843272889
GO:0140791	histone H2AXS140 phosphatase activity	16/1249	81/18639	0.197530864197531	2.94778044657949	7.98427003703061e-05	0.00236664843272889
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	16/1249	81/18639	0.197530864197531	2.94778044657949	7.98427003703061e-05	0.00236664843272889
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	16/1249	81/18639	0.197530864197531	2.94778044657949	7.98427003703061e-05	0.00236664843272889
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	16/1249	81/18639	0.197530864197531	2.94778044657949	7.98427003703061e-05	0.00236664843272889
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	16/1249	81/18639	0.197530864197531	2.94778044657949	7.98427003703061e-05	0.00236664843272889
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	16/1249	81/18639	0.197530864197531	2.94778044657949	7.98427003703061e-05	0.00236664843272889
GO:1990439	MAP kinase serine/threonine phosphatase activity	16/1249	81/18639	0.197530864197531	2.94778044657949	7.98427003703061e-05	0.00236664843272889
GO:0051087	protein-folding chaperone binding	22/1249	134/18639	0.164179104477612	2.45006751669993	8.03687582159946e-05	0.00236664843272889
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	16/1249	82/18639	0.195121951219512	2.91183190454803	9.31140262935059e-05	0.00260486488556083
GO:0033549	MAP kinase phosphatase activity	16/1249	82/18639	0.195121951219512	2.91183190454803	9.31140262935059e-05	0.00260486488556083
GO:0035925	mRNA 3'-UTR AU-rich region binding	9/1249	30/18639	0.3	4.47694155324259	0.000104574124594905	0.00285410842491949
GO:0017018	myosin phosphatase activity	16/1249	84/18639	0.19047619047619	2.84250257348736	0.000125555655011724	0.00334516137995521
GO:0140104	molecular carrier activity	33/1249	249/18639	0.132530120481928	1.97776534480597	0.000136173361432761	0.00354367421961069
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	8/1249	26/18639	0.307692307692308	4.59173492640266	0.000208895819929071	0.00529581437415088
GO:0042288	MHC class I protein binding	7/1249	20/18639	0.35	5.22309847878303	0.000212968406467194	0.00529581437415088
GO:0032395	MHC class II receptor activity	5/1249	10/18639	0.5	7.46156925540432	0.000254085154703291	0.00618089756767354
GO:0003712	transcription coregulator activity	54/1249	495/18639	0.109090909090909	1.62797874663367	0.000277808350222235	0.00661420306167407
GO:0004722	protein serine/threonine phosphatase activity	17/1249	103/18639	0.16504854368932	2.46304227848298	0.000469813632397923	0.0109525303052766
GO:1990841	promoter-specific chromatin binding	13/1249	68/18639	0.191176470588235	2.85295295059577	0.000508353538786392	0.0116091348959586
GO:0003714	transcription corepressor activity	27/1249	204/18639	0.132352941176471	1.97512127348938	0.000542907864046876	0.0121502779973691
GO:0140296	general transcription initiation factor binding	11/1249	53/18639	0.207547169811321	3.09725516262066	0.000655294716939574	0.0143779370246154
GO:0140789	histone phosphatase activity	20/1249	136/18639	0.147058823529412	2.19457919276598	0.000731964992987544	0.0155533429718095
GO:0060229	lipase activator activity	7/1249	24/18639	0.291666666666667	4.35258206565252	0.000750386985488914	0.0155533429718095
GO:0004725	protein tyrosine phosphatase activity	16/1249	98/18639	0.163265306122449	2.43643077727488	0.000770312022716078	0.0155533429718095
GO:0016411	acylglycerol O-acyltransferase activity	8/1249	31/18639	0.258064516129032	3.85113251891836	0.000781426256263176	0.0155533429718095
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	15/1249	89/18639	0.168539325842697	2.51513570406887	0.000792261438242306	0.0155533429718095
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	15/1249	89/18639	0.168539325842697	2.51513570406887	0.000792261438242306	0.0155533429718095
GO:0030228	lipoprotein particle receptor activity	6/1249	18/18639	0.333333333333333	4.97437950360288	0.000824107647196762	0.0158995940898823
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	19/1249	128/18639	0.1484375	2.21515337269816	0.000875299718978474	0.0166010234836765
GO:0140793	histone H2AXY142 phosphatase activity	15/1249	90/18639	0.166666666666667	2.48718975180144	0.000892944775548825	0.0166534200639856
GO:0140313	molecular sequestering activity	11/1249	55/18639	0.2	2.98462770216173	0.000909639081090022	0.0166866578973727
GO:0001217	DNA-binding transcription repressor activity	33/1249	278/18639	0.118705035971223	1.77145169372908	0.0010048505325342	0.018135931385577
GO:0003689	DNA clamp loader activity	22/1249	160/18639	0.1375	2.05193154523619	0.00102818963335358	0.0182626063448041
GO:0000510	H3-H4 histone complex chaperone activity	21/1249	151/18639	0.139072847682119	2.07540336905286	0.00114250198734373	0.0190814884154871
GO:0140584	chromatin extrusion motor activity	21/1249	151/18639	0.139072847682119	2.07540336905286	0.00114250198734373	0.0190814884154871
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	21/1249	151/18639	0.139072847682119	2.07540336905286	0.00114250198734373	0.0190814884154871
GO:0140849	ATP-dependent H2AZ histone chaperone activity	21/1249	151/18639	0.139072847682119	2.07540336905286	0.00114250198734373	0.0190814884154871
GO:0001216	DNA-binding transcription activator activity	51/1249	491/18639	0.103869653767821	1.55006123024693	0.00122783084351093	0.0198849473823421
GO:0015616	DNA translocase activity	21/1249	152/18639	0.138157894736842	2.06174939951962	0.00124391985412328	0.0198849473823421
GO:0140674	ATP-dependent histone chaperone activity	21/1249	152/18639	0.138157894736842	2.06174939951962	0.00124391985412328	0.0198849473823421
GO:0001222	transcription corepressor binding	10/1249	49/18639	0.204081632653061	3.0455384715936	0.00130805483141994	0.0206156810754777
GO:0061775	cohesin loader activity	21/1249	153/18639	0.137254901960784	2.04827391324825	0.00135294666671464	0.0210270461118568
GO:0140713	histone chaperone activity	22/1249	164/18639	0.134146341463415	2.00188443437677	0.0014257535919324	0.0218550447859227
GO:0016004	phospholipase activator activity	6/1249	20/18639	0.3	4.47694155324259	0.00153253830496963	0.023174464368392
GO:0035198	miRNA binding	9/1249	42/18639	0.214285714285714	3.19781539517328	0.00157464238314924	0.0234446301601527
GO:0044548	S100 protein binding	5/1249	14/18639	0.357142857142857	5.3296923252888	0.00160965645907085	0.0234446301601527
GO:0005044	scavenger receptor activity	7/1249	27/18639	0.259259259259259	3.86896183613558	0.00161325873309362	0.0234446301601527
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	6/1249	21/18639	0.285714285714286	4.26375386023104	0.00202512859567006	0.02837758824064
GO:0097718	disordered domain specific binding	7/1249	28/18639	0.25	3.73078462770216	0.00202816714740647	0.02837758824064
GO:0140658	ATP-dependent chromatin remodeler activity	21/1249	158/18639	0.132911392405063	1.9834551185252	0.00202878200111814	0.02837758824064
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	31/1249	268/18639	0.115671641791045	1.7261839322204	0.00211894860844979	0.0292728826278434
GO:0008186	ATP-dependent activity, acting on RNA	13/1249	79/18639	0.164556962025316	2.45570633722168	0.00216025198722661	0.0294795362647144
GO:0031490	chromatin DNA binding	18/1249	128/18639	0.140625	2.09856635308247	0.0022003125331208	0.0296644545127973
GO:0005041	low-density lipoprotein particle receptor activity	5/1249	15/18639	0.333333333333333	4.97437950360288	0.00228223775354518	0.0303387179659322
GO:0003727	single-stranded RNA binding	14/1249	89/18639	0.157303370786517	2.34745999046428	0.00230454962207706	0.0303387179659322
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	49/1249	484/18639	0.101239669421488	1.51081360956534	0.00256397055439629	0.0333614308182494
GO:0001618	virus receptor activity	13/1249	81/18639	0.160493827160494	2.39507161284583	0.00271486582978944	0.034918791534878
GO:0003697	single-stranded DNA binding	17/1249	121/18639	0.140495867768595	2.096639294907	0.00290581590474488	0.0369500908796537
GO:0140272	exogenous protein binding	13/1249	82/18639	0.158536585365854	2.36586342244527	0.00303292863316781	0.0377701013747997
GO:0030957	Tat protein binding	4/1249	10/18639	0.4	5.96925540432346	0.00303780976204824	0.0377701013747997
GO:0019207	kinase regulator activity	32/1249	287/18639	0.111498257839721	1.66390394545602	0.00323562712085073	0.039168869116046
GO:0004721	phosphoprotein phosphatase activity	22/1249	175/18639	0.125714285714286	1.87605169850166	0.00325397502816999	0.039168869116046
GO:0016887	ATP hydrolysis activity	43/1249	417/18639	0.103117505995204	1.53883682485557	0.0032553215619234	0.039168869116046
GO:0042171	lysophosphatidic acid acyltransferase activity	6/1249	23/18639	0.260869565217391	3.89299265499356	0.00335717586470922	0.0394062849961207
GO:0071617	lysophospholipid acyltransferase activity	6/1249	23/18639	0.260869565217391	3.89299265499356	0.00335717586470922	0.0394062849961207
GO:0001540	amyloid-beta binding	13/1249	83/18639	0.156626506024096	2.3373590438616	0.0033807000532865	0.0394062849961207
GO:0004386	helicase activity	20/1249	155/18639	0.129032258064516	1.92556625945918	0.00362086673580161	0.0417706172923918
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	9/1249	48/18639	0.1875	2.79808847077662	0.00412827189435058	0.0471381249977378
GO:0048027	mRNA 5'-UTR binding	6/1249	24/18639	0.25	3.73078462770216	0.00422610549111598	0.0477677984298867
GO:0042608	T cell receptor binding	4/1249	11/18639	0.363636363636364	5.42659582211224	0.00452220102832539	0.0506034295069611
GO:0061980	regulatory RNA binding	10/1249	58/18639	0.172413793103448	2.57295491565666	0.00481012238488343	0.0532923460265798
GO:0003724	RNA helicase activity	12/1249	77/18639	0.155844155844156	2.32568392376239	0.00496950364154428	0.054518378185177
GO:0008137	NADH dehydrogenase (ubiquinone) activity	8/1249	41/18639	0.195121951219512	2.91183190454803	0.00521765009868073	0.0560756318100979
GO:0042287	MHC protein binding	8/1249	41/18639	0.195121951219512	2.91183190454803	0.00521765009868073	0.0560756318100979
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	11/1249	68/18639	0.161764705882353	2.41403711204258	0.00526178850764994	0.0560756318100979
GO:0036002	pre-mRNA binding	10/1249	59/18639	0.169491525423729	2.52934551030655	0.00545206886691806	0.0575469706383484
GO:0000900	mRNA regulatory element binding translation repressor activity	5/1249	18/18639	0.277777777777778	4.1453162530024	0.00550270407355074	0.0575469706383484
GO:0016830	carbon-carbon lyase activity	9/1249	51/18639	0.176470588235294	2.63349503131917	0.0062569865508057	0.0642345683518494
GO:0030544	Hsp70 protein binding	9/1249	51/18639	0.176470588235294	2.63349503131917	0.0062569865508057	0.0642345683518494
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	4/1249	12/18639	0.333333333333333	4.97437950360288	0.00642682650609173	0.0653783532756058
GO:0019887	protein kinase regulator activity	28/1249	255/18639	0.109803921568627	1.6386191305986	0.00691332361383359	0.0696632132166698
GO:0004712	protein serine/threonine/tyrosine kinase activity	8/1249	43/18639	0.186046511627907	2.77639786247603	0.00703480169212125	0.0696632132166698
GO:0048156	tau protein binding	8/1249	43/18639	0.186046511627907	2.77639786247603	0.00703480169212125	0.0696632132166698
GO:0003713	transcription coactivator activity	28/1249	256/18639	0.109375	1.6322182746197	0.00728172327135212	0.0714758626372195
GO:0001046	core promoter sequence-specific DNA binding	8/1249	44/18639	0.181818181818182	2.71329791105612	0.00810491605403833	0.0780290562403524
GO:0003954	NADH dehydrogenase activity	8/1249	44/18639	0.181818181818182	2.71329791105612	0.00810491605403833	0.0780290562403524
GO:0005525	GTP binding	38/1249	378/18639	0.100529100529101	1.50020969156277	0.00815853403049262	0.0780290562403524
GO:0008035	high-density lipoprotein particle binding	4/1249	13/18639	0.307692307692308	4.59173492640266	0.00879659083060523	0.082717522180229
GO:0017154	semaphorin receptor activity	4/1249	13/18639	0.307692307692308	4.59173492640266	0.00879659083060523	0.082717522180229
GO:0017069	snRNA binding	9/1249	54/18639	0.166666666666667	2.48718975180144	0.00914292062137572	0.0852577347943286
GO:0051019	mitogen-activated protein kinase binding	6/1249	28/18639	0.214285714285714	3.19781539517328	0.00940706127998881	0.0869958807628717
GO:0016922	nuclear receptor binding	17/1249	137/18639	0.124087591240876	1.8517763115602	0.0101787381224733	0.0933607209758006
GO:0043394	proteoglycan binding	7/1249	37/18639	0.189189189189189	2.82329647501785	0.0104229307255988	0.0948232478206918
GO:0035613	RNA stem-loop binding	5/1249	21/18639	0.238095238095238	3.5531282168592	0.0110551668954751	0.0989658540482928
GO:0070182	DNA polymerase binding	5/1249	21/18639	0.238095238095238	3.5531282168592	0.0110551668954751	0.0989658540482928
GO:0019001	guanyl nucleotide binding	39/1249	400/18639	0.0975	1.45500600480384	0.011980873546164	0.105241095869351
GO:0032561	guanyl ribonucleotide binding	39/1249	400/18639	0.0975	1.45500600480384	0.011980873546164	0.105241095869351
GO:0140030	modification-dependent protein binding	20/1249	173/18639	0.115606936416185	1.72521832494898	0.0120383022978346	0.105241095869351
GO:0003823	antigen binding	20/1249	174/18639	0.114942528735632	1.71530327710444	0.0127736125490572	0.110803662344147
GO:0016504	peptidase activator activity	9/1249	57/18639	0.157894736842105	2.35628502802242	0.012936823880317	0.111356199400575
GO:0008187	poly-pyrimidine tract binding	6/1249	30/18639	0.2	2.98462770216173	0.0132290565067464	0.1130023987103
GO:0061133	endopeptidase activator activity	5/1249	22/18639	0.227272727272727	3.39162238882015	0.0135336015131571	0.114712078869065
GO:0140693	molecular condensate scaffold activity	8/1249	48/18639	0.166666666666667	2.48718975180144	0.0136342327878335	0.114712078869065
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	9/1249	58/18639	0.155172413793103	2.315659424091	0.014429483338662	0.120496954148976
GO:0000774	adenyl-nucleotide exchange factor activity	4/1249	15/18639	0.266666666666667	3.97950360288231	0.0150855925158276	0.124123367832435
GO:0050780	dopamine receptor binding	4/1249	15/18639	0.266666666666667	3.97950360288231	0.0150855925158276	0.124123367832435
GO:0005164	tumor necrosis factor receptor binding	6/1249	31/18639	0.193548387096774	2.88834938918877	0.0154974478921252	0.126581344461957
GO:0070888	E-box binding	9/1249	59/18639	0.152542372881356	2.2764109592759	0.0160454179435759	0.130107410716387
GO:0008171	O-methyltransferase activity	5/1249	23/18639	0.217391304347826	3.24416054582797	0.0163603864155038	0.131477669654652
GO:0016791	phosphatase activity	28/1249	273/18639	0.102564102564103	1.53057830880089	0.0164493956672487	0.131477669654652
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	9/1249	60/18639	0.15	2.2384707766213	0.0177900706978586	0.139321205202003
GO:0005126	cytokine receptor binding	28/1249	275/18639	0.101818181818182	1.51944683019143	0.0179613947335063	0.139321205202003
GO:0043425	bHLH transcription factor binding	6/1249	32/18639	0.1875	2.79808847077662	0.0180214018338132	0.139321205202003
GO:0070717	poly-purine tract binding	6/1249	32/18639	0.1875	2.79808847077662	0.0180214018338132	0.139321205202003
GO:0001530	lipopolysaccharide binding	7/1249	41/18639	0.170731707317073	2.54785291647953	0.0180532392799736	0.139321205202003
GO:0017070	U6 snRNA binding	4/1249	16/18639	0.25	3.73078462770216	0.0190680793144693	0.145869992053324
GO:0001091	RNA polymerase II general transcription initiation factor binding	5/1249	24/18639	0.208333333333333	3.1089871897518	0.019553618237711	0.145869992053324
GO:0015149	hexose transmembrane transporter activity	5/1249	24/18639	0.208333333333333	3.1089871897518	0.019553618237711	0.145869992053324
GO:0035035	histone acetyltransferase binding	5/1249	24/18639	0.208333333333333	3.1089871897518	0.019553618237711	0.145869992053324
GO:0055056	D-glucose transmembrane transporter activity	5/1249	24/18639	0.208333333333333	3.1089871897518	0.019553618237711	0.145869992053324
GO:0004402	histone acetyltransferase activity	7/1249	42/18639	0.166666666666667	2.48718975180144	0.0204489214590307	0.1515386961103
GO:0017124	SH3 domain binding	14/1249	115/18639	0.121739130434783	1.81672990566366	0.0215869932442767	0.158920035791747
GO:0004549	tRNA-specific ribonuclease activity	4/1249	17/18639	0.235294117647059	3.51132670842556	0.0236419209635001	0.168153972490408
GO:0004659	prenyltransferase activity	4/1249	17/18639	0.235294117647059	3.51132670842556	0.0236419209635001	0.168153972490408
GO:0008429	phosphatidylethanolamine binding	4/1249	17/18639	0.235294117647059	3.51132670842556	0.0236419209635001	0.168153972490408
GO:1990226	histone methyltransferase binding	4/1249	17/18639	0.235294117647059	3.51132670842556	0.0236419209635001	0.168153972490408
GO:0016831	carboxy-lyase activity	6/1249	34/18639	0.176470588235294	2.63349503131917	0.0238831383459168	0.168153972490408
GO:0090482	vitamin transmembrane transporter activity	6/1249	34/18639	0.176470588235294	2.63349503131917	0.0238831383459168	0.168153972490408
GO:0016860	intramolecular oxidoreductase activity	8/1249	53/18639	0.150943396226415	2.25254920917866	0.0238931918015861	0.168153972490408
GO:0008094	ATP-dependent activity, acting on DNA	22/1249	210/18639	0.104761904761905	1.56337641541805	0.0249751218011819	0.171843866663877
GO:0003680	minor groove of adenine-thymine-rich DNA binding	3/1249	10/18639	0.3	4.47694155324259	0.0252310079157215	0.171843866663877
GO:0008190	eukaryotic initiation factor 4E binding	3/1249	10/18639	0.3	4.47694155324259	0.0252310079157215	0.171843866663877
GO:0031720	haptoglobin binding	3/1249	10/18639	0.3	4.47694155324259	0.0252310079157215	0.171843866663877
GO:0051880	G-quadruplex DNA binding	3/1249	10/18639	0.3	4.47694155324259	0.0252310079157215	0.171843866663877
GO:0048029	monosaccharide binding	10/1249	74/18639	0.135135135135135	2.01664033929847	0.0253389079531186	0.171843866663877
GO:0003735	structural constituent of ribosome	19/1249	175/18639	0.108571428571429	1.6202264668878	0.0256555347194489	0.172943032235321
GO:0042393	histone binding	25/1249	247/18639	0.101214574898785	1.51043912052719	0.0259123630584679	0.1736283488768
GO:0140463	chromatin-protein adaptor activity	8/1249	54/18639	0.148148148148148	2.21083533493461	0.0264584563546661	0.176232218219473
GO:0008143	poly(A) binding	5/1249	26/18639	0.192307692307692	2.86983432900166	0.0271018324417464	0.178393826484201
GO:0015145	monosaccharide transmembrane transporter activity	5/1249	26/18639	0.192307692307692	2.86983432900166	0.0271018324417464	0.178393826484201
GO:0030695	GTPase regulator activity	44/1249	489/18639	0.0899795501022495	1.34277728931612	0.0283775269720385	0.185698553694217
GO:0034185	apolipoprotein binding	4/1249	18/18639	0.222222222222222	3.31625300240192	0.0288245543606284	0.185857714463441
GO:0050811	GABA receptor binding	4/1249	18/18639	0.222222222222222	3.31625300240192	0.0288245543606284	0.185857714463441
GO:0008009	chemokine activity	7/1249	45/18639	0.155555555555556	2.32137710168135	0.0289427313007121	0.185857714463441
GO:0008374	O-acyltransferase activity	8/1249	55/18639	0.145454545454545	2.17063832884489	0.0292089760646422	0.185857714463441
GO:0060589	nucleoside-triphosphatase regulator activity	44/1249	490/18639	0.0897959183673469	1.34003692750118	0.0292323125518906	0.185857714463441
GO:0042578	phosphoric ester hydrolase activity	34/1249	363/18639	0.09366391184573	1.397759529938	0.0303080258262412	0.191608366664203
GO:0035255	ionotropic glutamate receptor binding	5/1249	27/18639	0.185185185185185	2.76354416866827	0.031482733069382	0.19791673204853
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	3/1249	11/18639	0.272727272727273	4.06994686658418	0.0329968104984951	0.200670820368565
GO:0005114	type II transforming growth factor beta receptor binding	3/1249	11/18639	0.272727272727273	4.06994686658418	0.0329968104984951	0.200670820368565
GO:0008432	JUN kinase binding	3/1249	11/18639	0.272727272727273	4.06994686658418	0.0329968104984951	0.200670820368565
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	3/1249	11/18639	0.272727272727273	4.06994686658418	0.0329968104984951	0.200670820368565
GO:0048185	activin binding	3/1249	11/18639	0.272727272727273	4.06994686658418	0.0329968104984951	0.200670820368565
GO:0140031	phosphorylation-dependent protein binding	3/1249	11/18639	0.272727272727273	4.06994686658418	0.0329968104984951	0.200670820368565
GO:0015245	fatty acid transmembrane transporter activity	4/1249	19/18639	0.210526315789474	3.14171337069656	0.0346279014145034	0.208325923025964
GO:0140036	ubiquitin-modified protein reader activity	4/1249	19/18639	0.210526315789474	3.14171337069656	0.0346279014145034	0.208325923025964
GO:0061733	protein-lysine-acetyltransferase activity	7/1249	47/18639	0.148936170212766	2.22259509735448	0.0357663344386559	0.214024215170353
GO:0051119	sugar transmembrane transporter activity	5/1249	28/18639	0.178571428571429	2.6648461626444	0.0362817921540326	0.215953858618949
GO:0046332	SMAD binding	10/1249	79/18639	0.126582278481013	1.8890048747859	0.037748021555601	0.223492254606971
GO:0042162	telomeric DNA binding	6/1249	38/18639	0.157894736842105	2.35628502802242	0.0391386772311367	0.230506209587589
GO:0019209	kinase activator activity	16/1249	148/18639	0.108108108108108	1.61331227143877	0.0395674219987375	0.231811231500457
GO:0008201	heparin binding	18/1249	172/18639	0.104651162790698	1.56172379764277	0.0400530873630906	0.232562188308155
GO:0002039	p53 binding	9/1249	69/18639	0.130434782608696	1.94649632749678	0.0401112621478766	0.232562188308155
GO:0000339	RNA cap binding	4/1249	20/18639	0.2	2.98462770216173	0.0410585873240107	0.235346909432072
GO:0031418	L-ascorbic acid binding	4/1249	20/18639	0.2	2.98462770216173	0.0410585873240107	0.235346909432072
GO:0004526	ribonuclease P activity	3/1249	12/18639	0.25	3.73078462770216	0.0418534718292962	0.235346909432072
GO:0016840	carbon-nitrogen lyase activity	3/1249	12/18639	0.25	3.73078462770216	0.0418534718292962	0.235346909432072
GO:0035259	nuclear glucocorticoid receptor binding	3/1249	12/18639	0.25	3.73078462770216	0.0418534718292962	0.235346909432072
GO:0097677	STAT family protein binding	3/1249	12/18639	0.25	3.73078462770216	0.0418534718292962	0.235346909432072
GO:0070063	RNA polymerase binding	8/1249	59/18639	0.135593220338983	2.02347640824524	0.0421660047079378	0.235918796340912
GO:0030295	protein kinase activator activity	15/1249	139/18639	0.107913669064748	1.6104106306628	0.0458225209217578	0.253104286017782
GO:0001098	basal transcription machinery binding	8/1249	60/18639	0.133333333333333	1.98975180144115	0.045916148401796	0.253104286017782
GO:0001099	basal RNA polymerase II transcription machinery binding	8/1249	60/18639	0.133333333333333	1.98975180144115	0.045916148401796	0.253104286017782
GO:0009055	electron transfer activity	13/1249	116/18639	0.112068965517241	1.67242069517683	0.0467932268591355	0.25667461203614
GO:0001968	fibronectin binding	5/1249	30/18639	0.166666666666667	2.48718975180144	0.0471619305344909	0.257435123259001
GO:0032813	tumor necrosis factor receptor superfamily binding	7/1249	50/18639	0.14	2.08923939151321	0.0478604103530479	0.258723667560679
GO:0048020	CCR chemokine receptor binding	7/1249	50/18639	0.14	2.08923939151321	0.0478604103530479	0.258723667560679
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	4/1249	21/18639	0.19047619047619	2.84250257348736	0.0481182156601367	0.258866746748524
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	8/1249	61/18639	0.131147540983607	1.95713291945031	0.0498780159615861	0.267050238569449
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/1249	13/18639	0.230769230769231	3.443801194802	0.0517705361289035	0.270706681907678
GO:0005542	folic acid binding	3/1249	13/18639	0.230769230769231	3.443801194802	0.0517705361289035	0.270706681907678
GO:0051011	microtubule minus-end binding	3/1249	13/18639	0.230769230769231	3.443801194802	0.0517705361289035	0.270706681907678
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/1249	13/18639	0.230769230769231	3.443801194802	0.0517705361289035	0.270706681907678
GO:0097157	pre-mRNA intronic binding	3/1249	13/18639	0.230769230769231	3.443801194802	0.0517705361289035	0.270706681907678
GO:0003743	translation initiation factor activity	7/1249	51/18639	0.137254901960784	2.04827391324825	0.0524048863062333	0.271635376508431
GO:0022853	active monoatomic ion transmembrane transporter activity	13/1249	118/18639	0.110169491525424	1.64407458169926	0.0524336383608767	0.271635376508431
GO:0070325	lipoprotein particle receptor binding	5/1249	31/18639	0.161290322580645	2.40695782432398	0.0532512541195612	0.274599785068152
GO:0140035	ubiquitin-like protein reader activity	4/1249	22/18639	0.181818181818182	2.71329791105612	0.0558036854705766	0.28513389973322
GO:0140517	protein-RNA adaptor activity	4/1249	22/18639	0.181818181818182	2.71329791105612	0.0558036854705766	0.28513389973322
GO:0042056	chemoattractant activity	6/1249	42/18639	0.142857142857143	2.13187693011552	0.0594727146371952	0.302499853086461
GO:0051059	NF-kappaB binding	5/1249	32/18639	0.15625	2.33174039231385	0.0597753008391442	0.302663174837115
GO:0034212	protein N-acetyltransferase activity	7/1249	53/18639	0.132075471698113	1.97098055803133	0.0622812811603187	0.309113515459737
GO:0005161	platelet-derived growth factor receptor binding	3/1249	14/18639	0.214285714285714	3.19781539517328	0.062706673824272	0.309113515459737
GO:0005344	oxygen carrier activity	3/1249	14/18639	0.214285714285714	3.19781539517328	0.062706673824272	0.309113515459737
GO:0043176	amine binding	3/1249	14/18639	0.214285714285714	3.19781539517328	0.062706673824272	0.309113515459737
GO:0070742	C2H2 zinc finger domain binding	3/1249	14/18639	0.214285714285714	3.19781539517328	0.062706673824272	0.309113515459737
GO:0098847	sequence-specific single stranded DNA binding	3/1249	14/18639	0.214285714285714	3.19781539517328	0.062706673824272	0.309113515459737
GO:0030296	protein tyrosine kinase activator activity	5/1249	33/18639	0.151515151515152	2.26108159254676	0.0667328681566434	0.327517892400368
GO:0019843	rRNA binding	8/1249	65/18639	0.123076923076923	1.83669397056106	0.0678934943771426	0.331759040209706
GO:0033218	amide binding	23/1249	247/18639	0.0931174089068826	1.38960399088502	0.0687768933004794	0.334614537405376
GO:0016651	oxidoreductase activity, acting on NAD(P)H	10/1249	88/18639	0.113636363636364	1.69581119441007	0.0695356540140517	0.336841544769367
GO:0019205	nucleobase-containing compound kinase activity	6/1249	44/18639	0.136363636363636	2.03497343329209	0.0716134915183063	0.345102584449615
GO:0005200	structural constituent of cytoskeleton	12/1249	112/18639	0.107142857142857	1.59890769758664	0.0718578214269529	0.345102584449615
GO:0005178	integrin binding	16/1249	161/18639	0.0993788819875776	1.48304482094993	0.0737275075233634	0.347878189605823
GO:0030332	cyclin binding	5/1249	34/18639	0.147058823529412	2.19457919276598	0.0741207526067686	0.347878189605823
GO:0004129	cytochrome-c oxidase activity	3/1249	15/18639	0.2	2.98462770216173	0.074611944151383	0.347878189605823
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	3/1249	15/18639	0.2	2.98462770216173	0.074611944151383	0.347878189605823
GO:0031386	protein tag activity	3/1249	15/18639	0.2	2.98462770216173	0.074611944151383	0.347878189605823
GO:0140776	protein-containing complex destabilizing activity	3/1249	15/18639	0.2	2.98462770216173	0.074611944151383	0.347878189605823
GO:0141047	molecular tag activity	3/1249	15/18639	0.2	2.98462770216173	0.074611944151383	0.347878189605823
GO:0031406	carboxylic acid binding	18/1249	187/18639	0.0962566844919786	1.436451835265	0.0773198792949941	0.35900807025352
GO:0019210	kinase inhibitor activity	10/1249	90/18639	0.111111111111111	1.65812650120096	0.078375986723501	0.362407971667759
GO:0016229	steroid dehydrogenase activity	5/1249	35/18639	0.142857142857143	2.13187693011552	0.0819338424677616	0.377300286919445
GO:0042974	nuclear retinoic acid receptor binding	4/1249	25/18639	0.16	2.38770216172938	0.0825209697419623	0.37844657844777
GO:0043177	organic acid binding	18/1249	189/18639	0.0952380952380952	1.42125128674368	0.0836077659672306	0.380833940313473
GO:0030145	manganese ion binding	8/1249	68/18639	0.117647058823529	1.75566335421278	0.0837222067177071	0.380833940313473
GO:0003924	GTPase activity	29/1249	331/18639	0.0876132930513595	1.30746530759351	0.0842738856099728	0.381791408897002
GO:0043021	ribonucleoprotein complex binding	17/1249	177/18639	0.096045197740113	1.43329578917371	0.0854877219534118	0.385728874459144
GO:0005159	insulin-like growth factor receptor binding	3/1249	16/18639	0.1875	2.79808847077662	0.0874297591137478	0.386695258688869
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/1249	16/18639	0.1875	2.79808847077662	0.0874297591137478	0.386695258688869
GO:0016675	oxidoreductase activity, acting on a heme group of donors	3/1249	16/18639	0.1875	2.79808847077662	0.0874297591137478	0.386695258688869
GO:0055102	lipase inhibitor activity	3/1249	16/18639	0.1875	2.79808847077662	0.0874297591137478	0.386695258688869
GO:0097027	ubiquitin-protein transferase activator activity	3/1249	16/18639	0.1875	2.79808847077662	0.0874297591137478	0.386695258688869
GO:0008080	N-acetyltransferase activity	8/1249	69/18639	0.115942028985507	1.73021895777492	0.0894416748580128	0.39403635498471
GO:0005539	glycosaminoglycan binding	22/1249	242/18639	0.0909090909090909	1.35664895552806	0.0898326353556702	0.394206741031353
GO:0015399	primary active transmembrane transporter activity	16/1249	166/18639	0.0963855421686747	1.43837479622252	0.0909038143172639	0.395191281266039
GO:0005085	guanyl-nucleotide exchange factor activity	21/1249	230/18639	0.091304347826087	1.36254742924775	0.0925024684760133	0.395191281266039
GO:0005160	transforming growth factor beta receptor binding	4/1249	26/18639	0.153846153846154	2.29586746320133	0.0925971765238197	0.395191281266039
GO:0008198	ferrous iron binding	4/1249	26/18639	0.153846153846154	2.29586746320133	0.0925971765238197	0.395191281266039
GO:0034237	protein kinase A regulatory subunit binding	4/1249	26/18639	0.153846153846154	2.29586746320133	0.0925971765238197	0.395191281266039
GO:0050681	nuclear androgen receptor binding	4/1249	26/18639	0.153846153846154	2.29586746320133	0.0925971765238197	0.395191281266039
GO:0050750	low-density lipoprotein particle receptor binding	4/1249	26/18639	0.153846153846154	2.29586746320133	0.0925971765238197	0.395191281266039
GO:0051213	dioxygenase activity	10/1249	93/18639	0.10752688172043	1.60463854954932	0.0928823118614551	0.395191281266039
GO:0097110	scaffold protein binding	8/1249	70/18639	0.114285714285714	1.70550154409242	0.0953815134589748	0.404287551365882
GO:0140097	catalytic activity, acting on DNA	29/1249	336/18639	0.0863095238095238	1.28800897861146	0.0969614542643189	0.409433461591596
GO:0004879	nuclear receptor activity	7/1249	59/18639	0.11864406779661	1.77054185721459	0.0982671881474608	0.411838889651718
GO:0031593	polyubiquitin modification-dependent protein binding	7/1249	59/18639	0.11864406779661	1.77054185721459	0.0982671881474608	0.411838889651718
GO:0004550	nucleoside diphosphate kinase activity	3/1249	17/18639	0.176470588235294	2.63349503131917	0.101098581574515	0.418997454747713
GO:0051787	misfolded protein binding	3/1249	17/18639	0.176470588235294	2.63349503131917	0.101098581574515	0.418997454747713
GO:0070403	NAD+ binding	3/1249	17/18639	0.176470588235294	2.63349503131917	0.101098581574515	0.418997454747713
GO:0098531	ligand-modulated transcription factor activity	7/1249	60/18639	0.116666666666667	1.74103282626101	0.105181476415756	0.434310229185355
GO:0043531	ADP binding	5/1249	38/18639	0.131578947368421	1.96357085668535	0.107846821648501	0.440722511525036
GO:0005518	collagen binding	8/1249	72/18639	0.111111111111111	1.65812650120096	0.10791596796949	0.440722511525036
GO:0042379	chemokine receptor binding	8/1249	72/18639	0.111111111111111	1.65812650120096	0.10791596796949	0.440722511525036
GO:0004860	protein kinase inhibitor activity	9/1249	84/18639	0.107142857142857	1.59890769758664	0.10896075971511	0.441764819279738
GO:0051117	ATPase binding	9/1249	84/18639	0.107142857142857	1.59890769758664	0.10896075971511	0.441764819279738
GO:0036408	histone H3K14 acetyltransferase activity	4/1249	28/18639	0.142857142857143	2.13187693011552	0.114383105924032	0.455296619973064
GO:0051537	2 iron, 2 sulfur cluster binding	4/1249	28/18639	0.142857142857143	2.13187693011552	0.114383105924032	0.455296619973064
GO:0141052	histone H3 demethylase activity	4/1249	28/18639	0.142857142857143	2.13187693011552	0.114383105924032	0.455296619973064
GO:0031690	adrenergic receptor binding	3/1249	18/18639	0.166666666666667	2.48718975180144	0.115553387017292	0.455296619973064
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	3/1249	18/18639	0.166666666666667	2.48718975180144	0.115553387017292	0.455296619973064
GO:0098641	cadherin binding involved in cell-cell adhesion	3/1249	18/18639	0.166666666666667	2.48718975180144	0.115553387017292	0.455296619973064
GO:1901611	phosphatidylglycerol binding	3/1249	18/18639	0.166666666666667	2.48718975180144	0.115553387017292	0.455296619973064
GO:1990381	ubiquitin-specific protease binding	3/1249	18/18639	0.166666666666667	2.48718975180144	0.115553387017292	0.455296619973064
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	12/1249	122/18639	0.0983606557377049	1.46784968958774	0.116677314911827	0.458111983811701
GO:0031491	nucleosome binding	8/1249	74/18639	0.108108108108108	1.61331227143877	0.121308280816268	0.47462925256435
GO:0002020	protease binding	13/1249	136/18639	0.0955882352941176	1.42647647529789	0.124202479237375	0.482873886640842
GO:0005048	signal sequence binding	6/1249	51/18639	0.117647058823529	1.75566335421278	0.124278533827134	0.482873886640842
GO:0004629	phospholipase C activity	4/1249	29/18639	0.137931034482759	2.05836393252533	0.126043370627099	0.484682239627916
GO:0010484	histone H3 acetyltransferase activity	4/1249	29/18639	0.137931034482759	2.05836393252533	0.126043370627099	0.484682239627916
GO:0051861	glycolipid binding	4/1249	29/18639	0.137931034482759	2.05836393252533	0.126043370627099	0.484682239627916
GO:0015144	carbohydrate transmembrane transporter activity	5/1249	40/18639	0.125	1.86539231385108	0.127078484077494	0.48532704328572
GO:0032451	demethylase activity	5/1249	40/18639	0.125	1.86539231385108	0.127078484077494	0.48532704328572
GO:0003725	double-stranded RNA binding	8/1249	75/18639	0.106666666666667	1.59180144115292	0.128318770480886	0.488396952952759
GO:0043022	ribosome binding	11/1249	112/18639	0.0982142857142857	1.46566538945442	0.130024641393111	0.490883954766394
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	3/1249	19/18639	0.157894736842105	2.35628502802242	0.130726915567816	0.490883954766394
GO:0008301	DNA binding, bending	3/1249	19/18639	0.157894736842105	2.35628502802242	0.130726915567816	0.490883954766394
GO:0097001	ceramide binding	3/1249	19/18639	0.157894736842105	2.35628502802242	0.130726915567816	0.490883954766394
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	20/1249	229/18639	0.0873362445414847	1.30333087430643	0.135753773855241	0.500167326557041
GO:0140318	protein transporter activity	5/1249	41/18639	0.121951219512195	1.81989494034252	0.137242455888213	0.500167326557041
GO:0032452	histone demethylase activity	4/1249	30/18639	0.133333333333333	1.98975180144115	0.138178976795192	0.500167326557041
GO:0043995	histone H4K5 acetyltransferase activity	4/1249	30/18639	0.133333333333333	1.98975180144115	0.138178976795192	0.500167326557041
GO:0043996	histone H4K8 acetyltransferase activity	4/1249	30/18639	0.133333333333333	1.98975180144115	0.138178976795192	0.500167326557041
GO:0043997	histone H4K12 acetyltransferase activity	4/1249	30/18639	0.133333333333333	1.98975180144115	0.138178976795192	0.500167326557041
GO:0001094	TFIID-class transcription factor complex binding	2/1249	10/18639	0.2	2.98462770216173	0.14124474994819	0.500167326557041
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/1249	10/18639	0.2	2.98462770216173	0.14124474994819	0.500167326557041
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/1249	10/18639	0.2	2.98462770216173	0.14124474994819	0.500167326557041
GO:0005031	tumor necrosis factor receptor activity	2/1249	10/18639	0.2	2.98462770216173	0.14124474994819	0.500167326557041
GO:0008140	cAMP response element binding protein binding	2/1249	10/18639	0.2	2.98462770216173	0.14124474994819	0.500167326557041
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/1249	10/18639	0.2	2.98462770216173	0.14124474994819	0.500167326557041
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/1249	10/18639	0.2	2.98462770216173	0.14124474994819	0.500167326557041
GO:0031996	thioesterase binding	2/1249	10/18639	0.2	2.98462770216173	0.14124474994819	0.500167326557041
GO:0032052	bile acid binding	2/1249	10/18639	0.2	2.98462770216173	0.14124474994819	0.500167326557041
GO:0033204	ribonuclease P RNA binding	2/1249	10/18639	0.2	2.98462770216173	0.14124474994819	0.500167326557041
GO:0043422	protein kinase B binding	2/1249	10/18639	0.2	2.98462770216173	0.14124474994819	0.500167326557041
GO:0141109	transporter activator activity	2/1249	10/18639	0.2	2.98462770216173	0.14124474994819	0.500167326557041
GO:0005096	GTPase activator activity	23/1249	271/18639	0.0848708487084871	1.26653943080664	0.144574515680094	0.510343479640459
GO:0043024	ribosomal small subunit binding	3/1249	20/18639	0.15	2.2384707766213	0.146550738199075	0.513460727164609
GO:0052745	inositol phosphate phosphatase activity	3/1249	20/18639	0.15	2.2384707766213	0.146550738199075	0.513460727164609
GO:0008307	structural constituent of muscle	5/1249	42/18639	0.119047619047619	1.7765641084296	0.147751880381594	0.513460727164609
GO:0043175	RNA polymerase core enzyme binding	5/1249	42/18639	0.119047619047619	1.7765641084296	0.147751880381594	0.513460727164609
GO:0051879	Hsp90 protein binding	5/1249	42/18639	0.119047619047619	1.7765641084296	0.147751880381594	0.513460727164609
GO:0140457	protein demethylase activity	4/1249	31/18639	0.129032258064516	1.92556625945918	0.150760861636027	0.521154092848297
GO:0003925	G protein activity	6/1249	54/18639	0.111111111111111	1.65812650120096	0.151362895599371	0.521154092848297
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	6/1249	54/18639	0.111111111111111	1.65812650120096	0.151362895599371	0.521154092848297
GO:0072341	modified amino acid binding	9/1249	91/18639	0.0989010989010989	1.47591479777228	0.155374263911725	0.533324543917855
GO:0005125	cytokine activity	20/1249	234/18639	0.0854700854700855	1.27548192400074	0.15705649227399	0.536146462227582
GO:1901681	sulfur compound binding	23/1249	275/18639	0.0836363636363636	1.24811703908581	0.160656198845621	0.536146462227582
GO:0031369	translation initiation factor binding	4/1249	32/18639	0.125	1.86539231385108	0.163758798892724	0.536146462227582
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/1249	32/18639	0.125	1.86539231385108	0.163758798892724	0.536146462227582
GO:0051015	actin filament binding	18/1249	209/18639	0.0861244019138756	1.28524637892132	0.164424345650641	0.536146462227582
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/1249	11/18639	0.181818181818182	2.71329791105612	0.165299847603678	0.536146462227582
GO:0001851	complement component C3b binding	2/1249	11/18639	0.181818181818182	2.71329791105612	0.165299847603678	0.536146462227582
GO:0010854	adenylate cyclase regulator activity	2/1249	11/18639	0.181818181818182	2.71329791105612	0.165299847603678	0.536146462227582
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/1249	11/18639	0.181818181818182	2.71329791105612	0.165299847603678	0.536146462227582
GO:0019206	nucleoside kinase activity	2/1249	11/18639	0.181818181818182	2.71329791105612	0.165299847603678	0.536146462227582
GO:0019215	intermediate filament binding	2/1249	11/18639	0.181818181818182	2.71329791105612	0.165299847603678	0.536146462227582
GO:0019864	IgG binding	2/1249	11/18639	0.181818181818182	2.71329791105612	0.165299847603678	0.536146462227582
GO:0032050	clathrin heavy chain binding	2/1249	11/18639	0.181818181818182	2.71329791105612	0.165299847603678	0.536146462227582
GO:0032404	mismatch repair complex binding	2/1249	11/18639	0.181818181818182	2.71329791105612	0.165299847603678	0.536146462227582
GO:0034056	estrogen response element binding	2/1249	11/18639	0.181818181818182	2.71329791105612	0.165299847603678	0.536146462227582
GO:0034713	type I transforming growth factor beta receptor binding	2/1249	11/18639	0.181818181818182	2.71329791105612	0.165299847603678	0.536146462227582
GO:0043522	leucine zipper domain binding	2/1249	11/18639	0.181818181818182	2.71329791105612	0.165299847603678	0.536146462227582
GO:0048407	platelet-derived growth factor binding	2/1249	11/18639	0.181818181818182	2.71329791105612	0.165299847603678	0.536146462227582
GO:0070697	activin receptor binding	2/1249	11/18639	0.181818181818182	2.71329791105612	0.165299847603678	0.536146462227582
GO:0001223	transcription coactivator binding	5/1249	44/18639	0.113636363636364	1.69581119441007	0.169741464093889	0.548447116139018
GO:0170055	lipid transmembrane transporter activity	6/1249	56/18639	0.107142857142857	1.59890769758664	0.170753357560047	0.548447116139018
GO:0008013	beta-catenin binding	10/1249	106/18639	0.0943396226415094	1.40784325573666	0.172533193181467	0.548447116139018
GO:0140098	catalytic activity, acting on RNA	31/1249	387/18639	0.0801033591731266	1.19539352412162	0.172948079168302	0.548447116139018
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	12/1249	132/18639	0.0909090909090909	1.35664895552806	0.174396720124014	0.548447116139018
GO:0016410	N-acyltransferase activity	9/1249	94/18639	0.0957446808510638	1.42881113401359	0.177809064392776	0.548447116139018
GO:0004407	histone deacetylase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0008649	rRNA methyltransferase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0032931	histone H3K56 acetyltransferase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0033558	protein lysine deacetylase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0043992	histone H3K9 acetyltransferase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0043993	histone H3K18 acetyltransferase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0043994	histone H3K23 acetyltransferase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0043999	histone H2AK5 acetyltransferase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0044012	histone H2AK9 acetyltransferase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0044014	histone H2BK5 acetyltransferase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0044015	histone H2BK12 acetyltransferase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0044016	histone H3K4 acetyltransferase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0044017	histone H3K27 acetyltransferase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0044018	histone H3K36 acetyltransferase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0046972	histone H4K16 acetyltransferase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0140908	histone H3K122 acetyltransferase activity	3/1249	22/18639	0.136363636363636	2.03497343329209	0.179874970172493	0.548447116139018
GO:0016829	lyase activity	17/1249	200/18639	0.085	1.26846677341873	0.186414179096146	0.562428117372546
GO:0003995	acyl-CoA dehydrogenase activity	2/1249	12/18639	0.166666666666667	2.48718975180144	0.189989122758555	0.562428117372546
GO:0004859	phospholipase inhibitor activity	2/1249	12/18639	0.166666666666667	2.48718975180144	0.189989122758555	0.562428117372546
GO:0008603	cAMP-dependent protein kinase regulator activity	2/1249	12/18639	0.166666666666667	2.48718975180144	0.189989122758555	0.562428117372546
GO:0016208	AMP binding	2/1249	12/18639	0.166666666666667	2.48718975180144	0.189989122758555	0.562428117372546
GO:0017166	vinculin binding	2/1249	12/18639	0.166666666666667	2.48718975180144	0.189989122758555	0.562428117372546
GO:0031543	peptidyl-proline dioxygenase activity	2/1249	12/18639	0.166666666666667	2.48718975180144	0.189989122758555	0.562428117372546
GO:0042301	phosphate ion binding	2/1249	12/18639	0.166666666666667	2.48718975180144	0.189989122758555	0.562428117372546
GO:0043047	single-stranded telomeric DNA binding	2/1249	12/18639	0.166666666666667	2.48718975180144	0.189989122758555	0.562428117372546
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/1249	12/18639	0.166666666666667	2.48718975180144	0.189989122758555	0.562428117372546
GO:1990247	N6-methyladenosine-containing RNA reader activity	2/1249	12/18639	0.166666666666667	2.48718975180144	0.189989122758555	0.562428117372546
GO:0019825	oxygen binding	4/1249	34/18639	0.117647058823529	1.75566335421278	0.190877810328676	0.563567994083874
GO:0030291	protein serine/threonine kinase inhibitor activity	5/1249	46/18639	0.108695652173913	1.62208027291398	0.19290845775082	0.568064642692547
GO:0016407	acetyltransferase activity	9/1249	96/18639	0.09375	1.39904423538831	0.193534102553121	0.568411183089087
GO:0001664	G protein-coupled receptor binding	24/1249	297/18639	0.0808080808080808	1.20591018269161	0.197122439144796	0.568844471983033
GO:0003887	DNA-directed DNA polymerase activity	3/1249	23/18639	0.130434782608696	1.94649632749678	0.197240085012884	0.568844471983033
GO:0043274	phospholipase binding	3/1249	23/18639	0.130434782608696	1.94649632749678	0.197240085012884	0.568844471983033
GO:0044013	histone H2B acetyltransferase activity	3/1249	23/18639	0.130434782608696	1.94649632749678	0.197240085012884	0.568844471983033
GO:0070577	lysine-acetylated histone binding	3/1249	23/18639	0.130434782608696	1.94649632749678	0.197240085012884	0.568844471983033
GO:0140102	catalytic activity, acting on a rRNA	3/1249	23/18639	0.130434782608696	1.94649632749678	0.197240085012884	0.568844471983033
GO:0140103	catalytic activity, acting on a glycoprotein	3/1249	23/18639	0.130434782608696	1.94649632749678	0.197240085012884	0.568844471983033
GO:0043495	protein-membrane adaptor activity	5/1249	47/18639	0.106382978723404	1.58756792668177	0.204887442021186	0.585006053541548
GO:0061749	forked DNA-dependent helicase activity	5/1249	47/18639	0.106382978723404	1.58756792668177	0.204887442021186	0.585006053541548
GO:1990518	single-stranded 3'-5' DNA helicase activity	5/1249	47/18639	0.106382978723404	1.58756792668177	0.204887442021186	0.585006053541548
GO:0010485	histone H4 acetyltransferase activity	4/1249	35/18639	0.114285714285714	1.70550154409242	0.204935096504278	0.585006053541548
GO:0004714	transmembrane receptor protein tyrosine kinase activity	6/1249	60/18639	0.1	1.49231385108086	0.212335329734283	0.598374695597679
GO:0043998	histone H2A acetyltransferase activity	3/1249	24/18639	0.125	1.86539231385108	0.214986051180963	0.598374695597679
GO:0050699	WW domain binding	3/1249	24/18639	0.125	1.86539231385108	0.214986051180963	0.598374695597679
GO:0070300	phosphatidic acid binding	3/1249	24/18639	0.125	1.86539231385108	0.214986051180963	0.598374695597679
GO:0140033	acetylation-dependent protein binding	3/1249	24/18639	0.125	1.86539231385108	0.214986051180963	0.598374695597679
GO:0005035	death receptor activity	2/1249	13/18639	0.153846153846154	2.29586746320133	0.215119774873037	0.598374695597679
GO:0005172	vascular endothelial growth factor receptor binding	2/1249	13/18639	0.153846153846154	2.29586746320133	0.215119774873037	0.598374695597679
GO:0019104	DNA N-glycosylase activity	2/1249	13/18639	0.153846153846154	2.29586746320133	0.215119774873037	0.598374695597679
GO:0089720	caspase binding	2/1249	13/18639	0.153846153846154	2.29586746320133	0.215119774873037	0.598374695597679
GO:0004521	RNA endonuclease activity	7/1249	73/18639	0.0958904109589041	1.43098588459809	0.216186121937639	0.598374695597679
GO:0043539	protein serine/threonine kinase activator activity	7/1249	73/18639	0.0958904109589041	1.43098588459809	0.216186121937639	0.598374695597679
GO:0009378	four-way junction helicase activity	5/1249	48/18639	0.104166666666667	1.5544935948759	0.217104670610061	0.598374695597679
GO:0036121	double-stranded DNA helicase activity	5/1249	48/18639	0.104166666666667	1.5544935948759	0.217104670610061	0.598374695597679
GO:0043138	3'-5' DNA helicase activity	5/1249	48/18639	0.104166666666667	1.5544935948759	0.217104670610061	0.598374695597679
GO:0000993	RNA polymerase II complex binding	4/1249	36/18639	0.111111111111111	1.65812650120096	0.219281330975493	0.599940854184783
GO:0045505	dynein intermediate chain binding	4/1249	36/18639	0.111111111111111	1.65812650120096	0.219281330975493	0.599940854184783
GO:0055106	ubiquitin-protein transferase regulator activity	4/1249	36/18639	0.111111111111111	1.65812650120096	0.219281330975493	0.599940854184783
GO:0015026	coreceptor activity	6/1249	61/18639	0.0983606557377049	1.46784968958774	0.22324277186766	0.609289418829051
GO:0003678	DNA helicase activity	7/1249	74/18639	0.0945945945945946	1.41164823750893	0.22609873220405	0.614970995786922
GO:0016853	isomerase activity	15/1249	180/18639	0.0833333333333333	1.24359487590072	0.226423637412164	0.614970995786922
GO:0003779	actin binding	34/1249	443/18639	0.0767494356659142	1.14534245906884	0.227838654567883	0.617315870366733
GO:0004713	protein tyrosine kinase activity	12/1249	140/18639	0.0857142857142857	1.27912615806931	0.228804213936833	0.618434578249557
GO:0035254	glutamate receptor binding	5/1249	49/18639	0.102040816326531	1.5227692357968	0.22954073288836	0.618930313498977
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	15/1249	181/18639	0.0828729281767956	1.23672418597862	0.232745605234366	0.625377358443827
GO:0008139	nuclear localization sequence binding	3/1249	25/18639	0.12	1.79077662129704	0.23304947137719	0.625377358443827
GO:0019213	deacetylase activity	4/1249	37/18639	0.108108108108108	1.61331227143877	0.233884367902167	0.626116286321831
GO:0019763	immunoglobulin receptor activity	2/1249	14/18639	0.142857142857143	2.13187693011552	0.240521958381164	0.634773753369156
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/1249	14/18639	0.142857142857143	2.13187693011552	0.240521958381164	0.634773753369156
GO:0030983	mismatched DNA binding	2/1249	14/18639	0.142857142857143	2.13187693011552	0.240521958381164	0.634773753369156
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/1249	14/18639	0.142857142857143	2.13187693011552	0.240521958381164	0.634773753369156
GO:0046030	inositol trisphosphate phosphatase activity	2/1249	14/18639	0.142857142857143	2.13187693011552	0.240521958381164	0.634773753369156
GO:1901612	cardiolipin binding	2/1249	14/18639	0.142857142857143	2.13187693011552	0.240521958381164	0.634773753369156
GO:0051536	iron-sulfur cluster binding	7/1249	76/18639	0.0921052631578947	1.37449959967974	0.246373185649667	0.647083727623447
GO:0098631	cell adhesion mediator activity	7/1249	76/18639	0.0921052631578947	1.37449959967974	0.246373185649667	0.647083727623447
GO:0140375	immune receptor activity	13/1249	156/18639	0.0833333333333333	1.24359487590072	0.246921136456847	0.647083727623447
GO:0004435	phosphatidylinositol phospholipase C activity	3/1249	26/18639	0.115384615384615	1.721900597401	0.251369335923282	0.651116404856836
GO:0008157	protein phosphatase 1 binding	3/1249	26/18639	0.115384615384615	1.721900597401	0.251369335923282	0.651116404856836
GO:0052742	phosphatidylinositol kinase activity	3/1249	26/18639	0.115384615384615	1.721900597401	0.251369335923282	0.651116404856836
GO:0070412	R-SMAD binding	3/1249	26/18639	0.115384615384615	1.721900597401	0.251369335923282	0.651116404856836
GO:0097602	cullin family protein binding	3/1249	26/18639	0.115384615384615	1.721900597401	0.251369335923282	0.651116404856836
GO:0005021	vascular endothelial growth factor receptor activity	5/1249	51/18639	0.0980392156862745	1.46305279517732	0.254991005823151	0.658972137450591
GO:0051540	metal cluster binding	7/1249	77/18639	0.0909090909090909	1.35664895552806	0.256715506021492	0.661900118060021
GO:0015078	proton transmembrane transporter activity	15/1249	185/18639	0.0810810810810811	1.20998420357908	0.258730375884181	0.665561587619306
GO:0000217	DNA secondary structure binding	4/1249	39/18639	0.102564102564103	1.53057830880089	0.263733697360075	0.672022840843383
GO:0016776	phosphotransferase activity, phosphate group as acceptor	4/1249	39/18639	0.102564102564103	1.53057830880089	0.263733697360075	0.672022840843383
GO:0004953	icosanoid receptor activity	2/1249	15/18639	0.133333333333333	1.98975180144115	0.266046575954976	0.672022840843383
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/1249	15/18639	0.133333333333333	1.98975180144115	0.266046575954976	0.672022840843383
GO:0033130	acetylcholine receptor binding	2/1249	15/18639	0.133333333333333	1.98975180144115	0.266046575954976	0.672022840843383
GO:0120283	protein serine/threonine kinase binding	2/1249	15/18639	0.133333333333333	1.98975180144115	0.266046575954976	0.672022840843383
GO:0141050	histone H3K deacetylase activity	2/1249	15/18639	0.133333333333333	1.98975180144115	0.266046575954976	0.672022840843383
GO:0141051	histone H4K deacetylase activity	2/1249	15/18639	0.133333333333333	1.98975180144115	0.266046575954976	0.672022840843383
GO:0019199	transmembrane receptor protein kinase activity	7/1249	78/18639	0.0897435897435897	1.33925602020078	0.267181331356517	0.673369166189059
GO:0005080	protein kinase C binding	5/1249	52/18639	0.0961538461538462	1.43491716450083	0.267965958287901	0.673829005222835
GO:0005385	zinc ion transmembrane transporter activity	3/1249	27/18639	0.111111111111111	1.65812650120096	0.26988728099051	0.674115775509778
GO:0008266	poly(U) RNA binding	3/1249	27/18639	0.111111111111111	1.65812650120096	0.26988728099051	0.674115775509778
GO:0015252	proton channel activity	3/1249	27/18639	0.111111111111111	1.65812650120096	0.26988728099051	0.674115775509778
GO:0016741	transferase activity, transferring one-carbon groups	17/1249	215/18639	0.0790697674418605	1.17996909155231	0.27423557231935	0.683451237027512
GO:0033293	monocarboxylic acid binding	7/1249	79/18639	0.0886075949367089	1.32230341235013	0.27776063373204	0.690698109213673
GO:0051018	protein kinase A binding	5/1249	53/18639	0.0943396226415094	1.40784325573666	0.28108139653215	0.697405948380212
GO:0032182	ubiquitin-like protein binding	10/1249	120/18639	0.0833333333333333	1.24359487590072	0.283806348460271	0.70260907948461
GO:0019789	SUMO transferase activity	3/1249	28/18639	0.107142857142857	1.59890769758664	0.288547781998487	0.70535492682533
GO:0046625	sphingolipid binding	3/1249	28/18639	0.107142857142857	1.59890769758664	0.288547781998487	0.70535492682533
GO:0046875	ephrin receptor binding	3/1249	28/18639	0.107142857142857	1.59890769758664	0.288547781998487	0.70535492682533
GO:0046966	nuclear thyroid hormone receptor binding	3/1249	28/18639	0.107142857142857	1.59890769758664	0.288547781998487	0.70535492682533
GO:0051959	dynein light intermediate chain binding	3/1249	28/18639	0.107142857142857	1.59890769758664	0.288547781998487	0.70535492682533
GO:0003688	DNA replication origin binding	2/1249	16/18639	0.125	1.86539231385108	0.291563264075153	0.70535492682533
GO:0030275	LRR domain binding	2/1249	16/18639	0.125	1.86539231385108	0.291563264075153	0.70535492682533
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/1249	16/18639	0.125	1.86539231385108	0.291563264075153	0.70535492682533
GO:0070411	I-SMAD binding	2/1249	16/18639	0.125	1.86539231385108	0.291563264075153	0.70535492682533
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	6/1249	67/18639	0.0895522388059701	1.33640046365451	0.291975386861596	0.70535492682533
GO:0042054	histone methyltransferase activity	6/1249	67/18639	0.0895522388059701	1.33640046365451	0.291975386861596	0.70535492682533
GO:0004540	RNA nuclease activity	10/1249	121/18639	0.0826446280991736	1.23331723229824	0.292479612195669	0.70535492682533
GO:0042169	SH2 domain binding	4/1249	41/18639	0.0975609756097561	1.45591595227401	0.294233842818251	0.708059505620695
GO:0008276	protein methyltransferase activity	8/1249	95/18639	0.0842105263157895	1.25668534827862	0.304187805853007	0.730202905419561
GO:0019842	vitamin binding	12/1249	150/18639	0.08	1.19385108086469	0.304740622726483	0.730202905419561
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	3/1249	29/18639	0.103448275862069	1.543772949394	0.307298291002878	0.73319144484482
GO:0097472	cyclin-dependent protein kinase activity	3/1249	29/18639	0.103448275862069	1.543772949394	0.307298291002878	0.73319144484482
GO:0031492	nucleosomal DNA binding	4/1249	42/18639	0.0952380952380952	1.42125128674368	0.309652996758952	0.737237666751632
GO:0016279	protein-lysine N-methyltransferase activity	6/1249	69/18639	0.0869565217391304	1.29766421833119	0.315814708085161	0.739121141253851
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/1249	17/18639	0.117647058823529	1.75566335421278	0.316958555075237	0.739121141253851
GO:0005092	GDP-dissociation inhibitor activity	2/1249	17/18639	0.117647058823529	1.75566335421278	0.316958555075237	0.739121141253851
GO:0019198	transmembrane receptor protein phosphatase activity	2/1249	17/18639	0.117647058823529	1.75566335421278	0.316958555075237	0.739121141253851
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/1249	17/18639	0.117647058823529	1.75566335421278	0.316958555075237	0.739121141253851
GO:0032183	SUMO binding	2/1249	17/18639	0.117647058823529	1.75566335421278	0.316958555075237	0.739121141253851
GO:0032977	membrane insertase activity	2/1249	17/18639	0.117647058823529	1.75566335421278	0.316958555075237	0.739121141253851
GO:0046965	nuclear retinoid X receptor binding	2/1249	17/18639	0.117647058823529	1.75566335421278	0.316958555075237	0.739121141253851
GO:0048038	quinone binding	2/1249	17/18639	0.117647058823529	1.75566335421278	0.316958555075237	0.739121141253851
GO:0004222	metalloendopeptidase activity	9/1249	110/18639	0.0818181818181818	1.22098405997525	0.317049283111572	0.739121141253851
GO:0030170	pyridoxal phosphate binding	5/1249	56/18639	0.0892857142857143	1.3324230813222	0.321078493828285	0.746958076078693
GO:0008106	alcohol dehydrogenase (NADP+) activity	3/1249	30/18639	0.1	1.49231385108086	0.326089325914844	0.753309756703952
GO:0033612	receptor serine/threonine kinase binding	3/1249	30/18639	0.1	1.49231385108086	0.326089325914844	0.753309756703952
GO:0048019	receptor antagonist activity	3/1249	30/18639	0.1	1.49231385108086	0.326089325914844	0.753309756703952
GO:0030246	carbohydrate binding	21/1249	280/18639	0.075	1.11923538831065	0.327799610686085	0.753309756703952
GO:0008028	monocarboxylic acid transmembrane transporter activity	6/1249	70/18639	0.0857142857142857	1.27912615806931	0.327847945947118	0.753309756703952
GO:0016278	lysine N-methyltransferase activity	6/1249	70/18639	0.0857142857142857	1.27912615806931	0.327847945947118	0.753309756703952
GO:0004527	exonuclease activity	7/1249	84/18639	0.0833333333333333	1.24359487590072	0.332006294366634	0.761301318434966
GO:0008170	N-methyltransferase activity	8/1249	98/18639	0.0816326530612245	1.21821538863744	0.33455323640764	0.762481627960985
GO:0004601	peroxidase activity	5/1249	57/18639	0.087719298245614	1.30904723779023	0.334565218345705	0.762481627960985
GO:0070279	vitamin B6 binding	5/1249	57/18639	0.087719298245614	1.30904723779023	0.334565218345705	0.762481627960985
GO:0030547	signaling receptor inhibitor activity	4/1249	44/18639	0.0909090909090909	1.35664895552806	0.340687091820691	0.767230803629851
GO:0043014	alpha-tubulin binding	4/1249	44/18639	0.0909090909090909	1.35664895552806	0.340687091820691	0.767230803629851
GO:0015172	acidic amino acid transmembrane transporter activity	2/1249	18/18639	0.111111111111111	1.65812650120096	0.34213420108248	0.767230803629851
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/1249	18/18639	0.111111111111111	1.65812650120096	0.34213420108248	0.767230803629851
GO:0017128	phospholipid scramblase activity	2/1249	18/18639	0.111111111111111	1.65812650120096	0.34213420108248	0.767230803629851
GO:0035615	clathrin adaptor activity	2/1249	18/18639	0.111111111111111	1.65812650120096	0.34213420108248	0.767230803629851
GO:0070064	proline-rich region binding	2/1249	18/18639	0.111111111111111	1.65812650120096	0.34213420108248	0.767230803629851
GO:0070628	proteasome binding	2/1249	18/18639	0.111111111111111	1.65812650120096	0.34213420108248	0.767230803629851
GO:0008408	3'-5' exonuclease activity	5/1249	58/18639	0.0862068965517241	1.28647745782833	0.348098777188338	0.777490083181139
GO:0017116	single-stranded DNA helicase activity	5/1249	58/18639	0.0862068965517241	1.28647745782833	0.348098777188338	0.777490083181139
GO:0016209	antioxidant activity	7/1249	86/18639	0.0813953488372093	1.21467406483326	0.354146955741283	0.789423194172302
GO:0051539	4 iron, 4 sulfur cluster binding	4/1249	45/18639	0.0888888888888889	1.32650120096077	0.356248089157033	0.791289630757548
GO:0001786	phosphatidylserine binding	5/1249	59/18639	0.0847457627118644	1.26467275515328	0.361661632075923	0.791289630757548
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	5/1249	59/18639	0.0847457627118644	1.26467275515328	0.361661632075923	0.791289630757548
GO:0045309	protein phosphorylated amino acid binding	5/1249	59/18639	0.0847457627118644	1.26467275515328	0.361661632075923	0.791289630757548
GO:0008378	galactosyltransferase activity	3/1249	32/18639	0.09375	1.39904423538831	0.363610627442707	0.791289630757548
GO:0030515	snoRNA binding	3/1249	32/18639	0.09375	1.39904423538831	0.363610627442707	0.791289630757548
GO:0042910	xenobiotic transmembrane transporter activity	3/1249	32/18639	0.09375	1.39904423538831	0.363610627442707	0.791289630757548
GO:0035591	signaling adaptor activity	10/1249	129/18639	0.0775193798449612	1.15683244269834	0.363941504422041	0.791289630757548
GO:0004857	enzyme inhibitor activity	30/1249	416/18639	0.0721153846153846	1.07618787337562	0.364519916175609	0.791289630757548
GO:0035401	histone H3Y41 kinase activity	9/1249	115/18639	0.0782608695652174	1.16789779649807	0.364852546795322	0.791289630757548
GO:0140801	histone H2AXY142 kinase activity	9/1249	115/18639	0.0782608695652174	1.16789779649807	0.364852546795322	0.791289630757548
GO:0003756	protein disulfide isomerase activity	2/1249	19/18639	0.105263157894737	1.57085668534828	0.367005646437147	0.791289630757548
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/1249	19/18639	0.105263157894737	1.57085668534828	0.367005646437147	0.791289630757548
GO:0043395	heparan sulfate proteoglycan binding	2/1249	19/18639	0.105263157894737	1.57085668534828	0.367005646437147	0.791289630757548
GO:0046624	sphingolipid transporter activity	2/1249	19/18639	0.105263157894737	1.57085668534828	0.367005646437147	0.791289630757548
GO:0050145	nucleoside monophosphate kinase activity	2/1249	19/18639	0.105263157894737	1.57085668534828	0.367005646437147	0.791289630757548
GO:0070003	threonine-type peptidase activity	2/1249	19/18639	0.105263157894737	1.57085668534828	0.367005646437147	0.791289630757548
GO:0019903	protein phosphatase binding	11/1249	144/18639	0.0763888888888889	1.13996196957566	0.371394830056162	0.799213105447778
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	5/1249	60/18639	0.0833333333333333	1.24359487590072	0.375236750470617	0.805267580656283
GO:0004197	cysteine-type endopeptidase activity	7/1249	88/18639	0.0795454545454545	1.18706783608705	0.376422459426648	0.805267580656283
GO:0035064	methylated histone binding	6/1249	74/18639	0.0810810810810811	1.20998420357908	0.376434671413433	0.805267580656283
GO:0004674	protein serine/threonine kinase activity	31/1249	433/18639	0.0715935334872979	1.06840021670916	0.377086874230467	0.805267580656283
GO:0071889	14-3-3 protein binding	3/1249	33/18639	0.0909090909090909	1.35664895552806	0.382257521597897	0.814754603177231
GO:0019208	phosphatase regulator activity	9/1249	117/18639	0.0769230769230769	1.14793373160067	0.384208426366062	0.81580498881143
GO:1990782	protein tyrosine kinase binding	9/1249	117/18639	0.0769230769230769	1.14793373160067	0.384208426366062	0.81580498881143
GO:0001784	phosphotyrosine residue binding	4/1249	47/18639	0.0851063829787234	1.27005434134542	0.38733138894839	0.817330619317352
GO:0001614	purinergic nucleotide receptor activity	2/1249	20/18639	0.1	1.49231385108086	0.391500636241377	0.817330619317352
GO:0001972	retinoic acid binding	2/1249	20/18639	0.1	1.49231385108086	0.391500636241377	0.817330619317352
GO:0010851	cyclase regulator activity	2/1249	20/18639	0.1	1.49231385108086	0.391500636241377	0.817330619317352
GO:0015095	magnesium ion transmembrane transporter activity	2/1249	20/18639	0.1	1.49231385108086	0.391500636241377	0.817330619317352
GO:0016502	nucleotide receptor activity	2/1249	20/18639	0.1	1.49231385108086	0.391500636241377	0.817330619317352
GO:0030742	GTP-dependent protein binding	2/1249	20/18639	0.1	1.49231385108086	0.391500636241377	0.817330619317352
GO:0061608	nuclear import signal receptor activity	2/1249	20/18639	0.1	1.49231385108086	0.391500636241377	0.817330619317352
GO:0140939	histone H4 methyltransferase activity	2/1249	20/18639	0.1	1.49231385108086	0.391500636241377	0.817330619317352
GO:0008168	methyltransferase activity	15/1249	204/18639	0.0735294117647059	1.09728959638299	0.393124928066358	0.819193285858948
GO:0015035	protein-disulfide reductase activity	3/1249	34/18639	0.0882352941176471	1.31674751565959	0.400778138817498	0.827535007853375
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	3/1249	34/18639	0.0882352941176471	1.31674751565959	0.400778138817498	0.827535007853375
GO:0051427	hormone receptor binding	3/1249	34/18639	0.0882352941176471	1.31674751565959	0.400778138817498	0.827535007853375
GO:0052866	phosphatidylinositol phosphate phosphatase activity	3/1249	34/18639	0.0882352941176471	1.31674751565959	0.400778138817498	0.827535007853375
GO:0140034	methylation-dependent protein binding	6/1249	76/18639	0.0789473684210526	1.17814251401121	0.400825714259633	0.827535007853375
GO:0038187	pattern recognition receptor activity	4/1249	48/18639	0.0833333333333333	1.24359487590072	0.402806545160965	0.830093046105193
GO:0001846	opsonin binding	2/1249	21/18639	0.0952380952380952	1.42125128674368	0.415557949674971	0.847011558627126
GO:0005123	death receptor binding	2/1249	21/18639	0.0952380952380952	1.42125128674368	0.415557949674971	0.847011558627126
GO:0008373	sialyltransferase activity	2/1249	21/18639	0.0952380952380952	1.42125128674368	0.415557949674971	0.847011558627126
GO:0009931	calcium-dependent protein serine/threonine kinase activity	2/1249	21/18639	0.0952380952380952	1.42125128674368	0.415557949674971	0.847011558627126
GO:0036122	BMP binding	2/1249	21/18639	0.0952380952380952	1.42125128674368	0.415557949674971	0.847011558627126
GO:0140312	cargo adaptor activity	2/1249	21/18639	0.0952380952380952	1.42125128674368	0.415557949674971	0.847011558627126
GO:0061630	ubiquitin protein ligase activity	25/1249	353/18639	0.0708215297450425	1.05687949793262	0.416633886364471	0.847660579712442
GO:0016763	pentosyltransferase activity	4/1249	49/18639	0.0816326530612245	1.21821538863744	0.418207950696307	0.848130011744037
GO:0034061	DNA polymerase activity	3/1249	35/18639	0.0857142857142857	1.27912615806931	0.419138424034363	0.848130011744037
GO:0043015	gamma-tubulin binding	3/1249	35/18639	0.0857142857142857	1.27912615806931	0.419138424034363	0.848130011744037
GO:0046982	protein heterodimerization activity	26/1249	369/18639	0.0704607046070461	1.05149485442012	0.424274658080728	0.856973542224431
GO:0019838	growth factor binding	10/1249	136/18639	0.0735294117647059	1.09728959638299	0.428021848565607	0.862984591972819
GO:0004518	nuclease activity	15/1249	209/18639	0.0717703349282297	1.0710386491011	0.430040662147666	0.865495505293595
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	9/1249	122/18639	0.0737704918032787	1.1008872671908	0.432753733906655	0.869392151241556
GO:0004033	aldo-keto reductase (NADPH) activity	3/1249	36/18639	0.0833333333333333	1.24359487590072	0.437307250676078	0.871245161511737
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	3/1249	36/18639	0.0833333333333333	1.24359487590072	0.437307250676078	0.871245161511737
GO:0044390	ubiquitin-like protein conjugating enzyme binding	3/1249	36/18639	0.0833333333333333	1.24359487590072	0.437307250676078	0.871245161511737
GO:0008093	cytoskeletal anchor activity	2/1249	22/18639	0.0909090909090909	1.35664895552806	0.439126247625218	0.871245161511737
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/1249	22/18639	0.0909090909090909	1.35664895552806	0.439126247625218	0.871245161511737
GO:0031683	G-protein beta/gamma-subunit complex binding	2/1249	22/18639	0.0909090909090909	1.35664895552806	0.439126247625218	0.871245161511737
GO:0070034	telomerase RNA binding	2/1249	22/18639	0.0909090909090909	1.35664895552806	0.439126247625218	0.871245161511737
GO:0061659	ubiquitin-like protein ligase activity	26/1249	372/18639	0.0698924731182796	1.04301505720706	0.440978507694049	0.873371593114408
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	12/1249	167/18639	0.0718562874251497	1.07232133011799	0.444306300478666	0.878407685928671
GO:0061134	peptidase regulator activity	16/1249	226/18639	0.0707964601769911	1.05650538129619	0.447214621841868	0.882598169031835
GO:0004620	phospholipase activity	8/1249	109/18639	0.073394495412844	1.09527622097678	0.448137137099108	0.882861719038559
GO:0048306	calcium-dependent protein binding	6/1249	80/18639	0.075	1.11923538831065	0.449337693475062	0.883671140595069
GO:0042805	actinin binding	3/1249	37/18639	0.0810810810810811	1.20998420357908	0.455256328567894	0.887112950293502
GO:0004842	ubiquitin-protein transferase activity	31/1249	449/18639	0.0690423162583519	1.03032804863044	0.458214992075388	0.887112950293502
GO:0019787	ubiquitin-like protein transferase activity	33/1249	479/18639	0.0688935281837161	1.02810766358389	0.460291198871906	0.887112950293502
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	2/1249	23/18639	0.0869565217391304	1.29766421833119	0.462163025016869	0.887112950293502
GO:0017134	fibroblast growth factor binding	2/1249	23/18639	0.0869565217391304	1.29766421833119	0.462163025016869	0.887112950293502
GO:0031681	G-protein beta-subunit binding	2/1249	23/18639	0.0869565217391304	1.29766421833119	0.462163025016869	0.887112950293502
GO:0030159	signaling receptor complex adaptor activity	4/1249	52/18639	0.0769230769230769	1.14793373160067	0.463770496959264	0.887112950293502
GO:0008173	RNA methyltransferase activity	5/1249	67/18639	0.0746268656716418	1.11366705304542	0.469295783963033	0.887112950293502
GO:0050840	extracellular matrix binding	5/1249	67/18639	0.0746268656716418	1.11366705304542	0.469295783963033	0.887112950293502
GO:0016755	aminoacyltransferase activity	34/1249	496/18639	0.0685483870967742	1.02295707533769	0.471004807906928	0.887112950293502
GO:0005109	frizzled binding	3/1249	38/18639	0.0789473684210526	1.17814251401121	0.47296010120055	0.887112950293502
GO:0005003	ephrin receptor activity	4/1249	53/18639	0.0754716981132075	1.12627460458933	0.478683892912497	0.887112950293502
GO:0005005	transmembrane-ephrin receptor activity	4/1249	53/18639	0.0754716981132075	1.12627460458933	0.478683892912497	0.887112950293502
GO:0005544	calcium-dependent phospholipid binding	4/1249	53/18639	0.0754716981132075	1.12627460458933	0.478683892912497	0.887112950293502
GO:0004519	endonuclease activity	9/1249	127/18639	0.0708661417322835	1.05754524879746	0.480943714822293	0.887112950293502
GO:0005540	hyaluronic acid binding	2/1249	24/18639	0.0833333333333333	1.24359487590072	0.484633659001952	0.887112950293502
GO:0030215	semaphorin receptor binding	2/1249	24/18639	0.0833333333333333	1.24359487590072	0.484633659001952	0.887112950293502
GO:0050431	transforming growth factor beta binding	2/1249	24/18639	0.0833333333333333	1.24359487590072	0.484633659001952	0.887112950293502
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/1249	24/18639	0.0833333333333333	1.24359487590072	0.484633659001952	0.887112950293502
GO:0030165	PDZ domain binding	6/1249	83/18639	0.072289156626506	1.07878109716689	0.485155287061986	0.887112950293502
GO:0051287	NAD binding	4/1249	54/18639	0.0740740740740741	1.10541766746731	0.493433166084699	0.887112950293502
GO:0000182	rDNA binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0004090	carbonyl reductase (NADPH) activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0004935	adrenergic receptor activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0004955	prostaglandin receptor activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0005131	growth hormone receptor binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0005345	purine nucleobase transmembrane transporter activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0005522	profilin binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0005528	FK506 binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0015279	store-operated calcium channel activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0016868	intramolecular phosphotransferase activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0031434	mitogen-activated protein kinase kinase binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0032356	oxidized DNA binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0042166	acetylcholine binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0042975	peroxisome proliferator activated receptor binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0043208	glycosphingolipid binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0043295	glutathione binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0045322	unmethylated CpG binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0050308	sugar-phosphatase activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0050815	phosphoserine residue binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0051378	serotonin binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0070513	death domain binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0098505	G-rich strand telomeric DNA binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0099122	RNA polymerase II C-terminal domain binding	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0140940	histone H2A methyltransferase activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0140999	histone H3K4 trimethyltransferase activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:1990259	histone H2AQ104 methyltransferase activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:1990757	ubiquitin ligase activator activity	1/1249	10/18639	0.1	1.49231385108086	0.500317197243129	0.887112950293502
GO:0000030	mannosyltransferase activity	2/1249	25/18639	0.08	1.19385108086469	0.506510544882366	0.887112950293502
GO:0001848	complement binding	2/1249	25/18639	0.08	1.19385108086469	0.506510544882366	0.887112950293502
GO:0003707	nuclear steroid receptor activity	2/1249	25/18639	0.08	1.19385108086469	0.506510544882366	0.887112950293502
GO:0017025	TBP-class protein binding	2/1249	25/18639	0.08	1.19385108086469	0.506510544882366	0.887112950293502
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/1249	25/18639	0.08	1.19385108086469	0.506510544882366	0.887112950293502
GO:0120020	cholesterol transfer activity	2/1249	25/18639	0.08	1.19385108086469	0.506510544882366	0.887112950293502
GO:0004177	aminopeptidase activity	3/1249	40/18639	0.075	1.11923538831065	0.507542501738265	0.887112950293502
GO:0004532	RNA exonuclease activity	3/1249	40/18639	0.075	1.11923538831065	0.507542501738265	0.887112950293502
GO:0015036	disulfide oxidoreductase activity	3/1249	40/18639	0.075	1.11923538831065	0.507542501738265	0.887112950293502
GO:0030331	nuclear estrogen receptor binding	3/1249	40/18639	0.075	1.11923538831065	0.507542501738265	0.887112950293502
GO:0098632	cell-cell adhesion mediator activity	4/1249	55/18639	0.0727272727272727	1.08531916442245	0.508003876627696	0.887112950293502
GO:0043130	ubiquitin binding	7/1249	100/18639	0.07	1.04461969575661	0.508893998174917	0.887112950293502
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	9/1249	130/18639	0.0692307692307692	1.0331403584406	0.50941011746298	0.887112950293502
GO:0019902	phosphatase binding	13/1249	190/18639	0.068421052631579	1.02105684547638	0.510381727216811	0.887112950293502
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	6/1249	86/18639	0.0697674418604651	1.04114919842851	0.520208860701646	0.887112950293502
GO:0050660	flavin adenine dinucleotide binding	6/1249	86/18639	0.0697674418604651	1.04114919842851	0.520208860701646	0.887112950293502
GO:0001727	lipid kinase activity	3/1249	41/18639	0.0731707317073171	1.09193696420551	0.524382659021424	0.887112950293502
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	3/1249	41/18639	0.0731707317073171	1.09193696420551	0.524382659021424	0.887112950293502
GO:0015175	neutral L-amino acid transmembrane transporter activity	3/1249	41/18639	0.0731707317073171	1.09193696420551	0.524382659021424	0.887112950293502
GO:0019865	immunoglobulin binding	2/1249	26/18639	0.0769230769230769	1.14793373160067	0.527772312295623	0.887112950293502
GO:0030247	polysaccharide binding	2/1249	26/18639	0.0769230769230769	1.14793373160067	0.527772312295623	0.887112950293502
GO:0070006	metalloaminopeptidase activity	2/1249	26/18639	0.0769230769230769	1.14793373160067	0.527772312295623	0.887112950293502
GO:0008081	phosphoric diester hydrolase activity	6/1249	87/18639	0.0689655172413793	1.02918196626267	0.531685617280351	0.887112950293502
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0000099	sulfur amino acid transmembrane transporter activity	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0002162	dystroglycan binding	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0004954	prostanoid receptor activity	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0005225	volume-sensitive anion channel activity	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0005536	D-glucose binding	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0008172	S-methyltransferase activity	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0008199	ferric iron binding	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0008526	phosphatidylinositol transfer activity	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0015173	aromatic amino acid transmembrane transporter activity	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0015205	nucleobase transmembrane transporter activity	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0015217	ADP transmembrane transporter activity	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0019203	carbohydrate phosphatase activity	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0031731	CCR6 chemokine receptor binding	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0032794	GTPase activating protein binding	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0045294	alpha-catenin binding	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0050998	nitric-oxide synthase binding	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0070990	snRNP binding	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0097493	structural molecule activity conferring elasticity	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0140537	transcription regulator activator activity	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0180030	inositol phosphate kinase activity	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:1900750	oligopeptide binding	1/1249	11/18639	0.0909090909090909	1.35664895552806	0.533818932207074	0.887112950293502
GO:0005319	lipid transporter activity	12/1249	178/18639	0.0674157303370786	1.00605428162755	0.534328979890814	0.887112950293502
GO:0048487	beta-tubulin binding	3/1249	42/18639	0.0714285714285714	1.06593846505776	0.540900325349306	0.89669253935685
GO:0106310	protein serine kinase activity	24/1249	361/18639	0.0664819944598338	0.992120011798913	0.546816497516453	0.896908161613122
GO:0004364	glutathione transferase activity	2/1249	27/18639	0.0740740740740741	1.10541766746731	0.548403114800032	0.896908161613122
GO:0004683	calcium/calmodulin-dependent protein kinase activity	2/1249	27/18639	0.0740740740740741	1.10541766746731	0.548403114800032	0.896908161613122
GO:0008320	protein transmembrane transporter activity	2/1249	27/18639	0.0740740740740741	1.10541766746731	0.548403114800032	0.896908161613122
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	2/1249	27/18639	0.0740740740740741	1.10541766746731	0.548403114800032	0.896908161613122
GO:0008375	acetylglucosaminyltransferase activity	3/1249	43/18639	0.0697674418604651	1.04114919842851	0.557081856234817	0.896908161613122
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3/1249	43/18639	0.0697674418604651	1.04114919842851	0.557081856234817	0.896908161613122
GO:0000340	RNA 7-methylguanosine cap binding	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0005095	GTPase inhibitor activity	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0005527	macrolide binding	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0008179	adenylate cyclase binding	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0010853	cyclase activator activity	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0015132	prostaglandin transmembrane transporter activity	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0015166	polyol transmembrane transporter activity	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0034452	dynactin binding	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0035497	cAMP response element binding	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0036009	protein-glutamine N-methyltransferase activity	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0045295	gamma-catenin binding	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0070410	co-SMAD binding	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0070679	inositol 1,4,5 trisphosphate binding	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0097371	MDM2/MDM4 family protein binding	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:1990817	poly(A) RNA polymerase activity	1/1249	12/18639	0.0833333333333333	1.24359487590072	0.565076187611485	0.896908161613122
GO:0019003	GDP binding	5/1249	75/18639	0.0666666666666667	0.994875900720576	0.570595416971043	0.898586066790692
GO:0061135	endopeptidase regulator activity	12/1249	184/18639	0.0652173913043478	0.97324816374839	0.581425148057599	0.898586066790692
GO:0000287	magnesium ion binding	15/1249	230/18639	0.0652173913043478	0.97324816374839	0.581682783752181	0.898586066790692
GO:0019888	protein phosphatase regulator activity	7/1249	107/18639	0.0654205607476635	0.976280089492154	0.581707375159245	0.898586066790692
GO:0017022	myosin binding	5/1249	76/18639	0.0657894736842105	0.981785428342674	0.582551029838044	0.898586066790692
GO:0005506	iron ion binding	10/1249	154/18639	0.0649350649350649	0.969034968234328	0.587560559427947	0.898586066790692
GO:0003785	actin monomer binding	2/1249	29/18639	0.0689655172413793	1.02918196626267	0.587732260298524	0.898586066790692
GO:0035250	UDP-galactosyltransferase activity	2/1249	29/18639	0.0689655172413793	1.02918196626267	0.587732260298524	0.898586066790692
GO:0043236	laminin binding	2/1249	29/18639	0.0689655172413793	1.02918196626267	0.587732260298524	0.898586066790692
GO:0106222	lncRNA binding	2/1249	29/18639	0.0689655172413793	1.02918196626267	0.587732260298524	0.898586066790692
GO:0046915	transition metal ion transmembrane transporter activity	3/1249	45/18639	0.0666666666666667	0.994875900720576	0.588391871650888	0.898586066790692
GO:0140303	intramembrane lipid transporter activity	3/1249	45/18639	0.0666666666666667	0.994875900720576	0.588391871650888	0.898586066790692
GO:1901981	phosphatidylinositol phosphate binding	12/1249	185/18639	0.0648648648648649	0.967987362863264	0.589080193711484	0.898586066790692
GO:0003730	mRNA 3'-UTR binding	17/1249	262/18639	0.0648854961832061	0.96829524688453	0.590877612823065	0.898586066790692
GO:0019905	syntaxin binding	4/1249	61/18639	0.0655737704918033	0.978566459725157	0.591013055971924	0.898586066790692
GO:0140767	enzyme-substrate adaptor activity	9/1249	139/18639	0.0647482014388489	0.966246378397682	0.591408432925687	0.898586066790692
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0004465	lipoprotein lipase activity	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0004535	poly(A)-specific ribonuclease activity	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0004993	G protein-coupled serotonin receptor activity	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0019855	calcium channel inhibitor activity	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0030955	potassium ion binding	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0035673	oligopeptide transmembrane transporter activity	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0043560	insulin receptor substrate binding	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0045159	myosin II binding	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0046974	histone H3K9 methyltransferase activity	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0070123	transforming growth factor beta receptor activity, type III	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0071714	icosanoid transmembrane transporter activity	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0071837	HMG box domain binding	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0140333	glycerophospholipid flippase activity	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0140666	annealing activity	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:1901338	catecholamine binding	1/1249	13/18639	0.0769230769230769	1.14793373160067	0.594239222006356	0.898586066790692
GO:0051219	phosphoprotein binding	6/1249	93/18639	0.0645161290322581	0.96278312972959	0.597890966747507	0.901378992017767
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	3/1249	46/18639	0.0652173913043478	0.97324816374839	0.603502636333806	0.901378992017767
GO:0015215	nucleotide transmembrane transporter activity	2/1249	30/18639	0.0666666666666667	0.994875900720576	0.60642104132593	0.901378992017767
GO:0031624	ubiquitin conjugating enzyme binding	2/1249	30/18639	0.0666666666666667	0.994875900720576	0.60642104132593	0.901378992017767
GO:0005504	fatty acid binding	3/1249	47/18639	0.0638297872340425	0.952540756009063	0.618241585019176	0.901378992017767
GO:0140359	ABC-type transporter activity	3/1249	47/18639	0.0638297872340425	0.952540756009063	0.618241585019176	0.901378992017767
GO:0140938	histone H3 methyltransferase activity	3/1249	47/18639	0.0638297872340425	0.952540756009063	0.618241585019176	0.901378992017767
GO:1902936	phosphatidylinositol bisphosphate binding	7/1249	111/18639	0.0630630630630631	0.941098825005951	0.620853989164652	0.901378992017767
GO:0005347	ATP transmembrane transporter activity	1/1249	14/18639	0.0714285714285714	1.06593846505776	0.621448242285217	0.901378992017767
GO:0005545	1-phosphatidylinositol binding	1/1249	14/18639	0.0714285714285714	1.06593846505776	0.621448242285217	0.901378992017767
GO:0008191	metalloendopeptidase inhibitor activity	1/1249	14/18639	0.0714285714285714	1.06593846505776	0.621448242285217	0.901378992017767
GO:0008474	palmitoyl-(protein) hydrolase activity	1/1249	14/18639	0.0714285714285714	1.06593846505776	0.621448242285217	0.901378992017767
GO:0008494	translation activator activity	1/1249	14/18639	0.0714285714285714	1.06593846505776	0.621448242285217	0.901378992017767
GO:0008559	ABC-type xenobiotic transporter activity	1/1249	14/18639	0.0714285714285714	1.06593846505776	0.621448242285217	0.901378992017767
GO:0015926	glucosidase activity	1/1249	14/18639	0.0714285714285714	1.06593846505776	0.621448242285217	0.901378992017767
GO:0019992	diacylglycerol binding	1/1249	14/18639	0.0714285714285714	1.06593846505776	0.621448242285217	0.901378992017767
GO:0032036	myosin heavy chain binding	1/1249	14/18639	0.0714285714285714	1.06593846505776	0.621448242285217	0.901378992017767
GO:0034236	protein kinase A catalytic subunit binding	1/1249	14/18639	0.0714285714285714	1.06593846505776	0.621448242285217	0.901378992017767
GO:0061665	SUMO ligase activity	1/1249	14/18639	0.0714285714285714	1.06593846505776	0.621448242285217	0.901378992017767
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/1249	14/18639	0.0714285714285714	1.06593846505776	0.621448242285217	0.901378992017767
GO:0098599	palmitoyl hydrolase activity	1/1249	14/18639	0.0714285714285714	1.06593846505776	0.621448242285217	0.901378992017767
GO:1990825	sequence-specific mRNA binding	1/1249	14/18639	0.0714285714285714	1.06593846505776	0.621448242285217	0.901378992017767
GO:0016757	glycosyltransferase activity	17/1249	267/18639	0.0636704119850187	0.950162377092685	0.622448214974279	0.901378992017767
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/1249	31/18639	0.0645161290322581	0.96278312972959	0.624458732554191	0.901378992017767
GO:0008327	methyl-CpG binding	2/1249	31/18639	0.0645161290322581	0.96278312972959	0.624458732554191	0.901378992017767
GO:0017147	Wnt-protein binding	2/1249	31/18639	0.0645161290322581	0.96278312972959	0.624458732554191	0.901378992017767
GO:0047499	calcium-independent phospholipase A2 activity	2/1249	31/18639	0.0645161290322581	0.96278312972959	0.624458732554191	0.901378992017767
GO:0070273	phosphatidylinositol-4-phosphate binding	2/1249	31/18639	0.0645161290322581	0.96278312972959	0.624458732554191	0.901378992017767
GO:0072349	modified amino acid transmembrane transporter activity	2/1249	31/18639	0.0645161290322581	0.96278312972959	0.624458732554191	0.901378992017767
GO:0000049	tRNA binding	5/1249	80/18639	0.0625	0.93269615692554	0.628504686177513	0.901378992017767
GO:0051020	GTPase binding	20/1249	315/18639	0.0634920634920635	0.94750085782912	0.632115267778858	0.901378992017767
GO:0016879	ligase activity, forming carbon-nitrogen bonds	3/1249	48/18639	0.0625	0.93269615692554	0.632603921009723	0.901378992017767
GO:0030971	receptor tyrosine kinase binding	5/1249	81/18639	0.0617283950617284	0.921181389556089	0.639501891670956	0.901378992017767
GO:0120013	lipid transfer activity	4/1249	65/18639	0.0615384615384615	0.918346985280532	0.64150758963239	0.901378992017767
GO:0160215	deacylase activity	4/1249	65/18639	0.0615384615384615	0.918346985280532	0.64150758963239	0.901378992017767
GO:0022884	macromolecule transmembrane transporter activity	2/1249	32/18639	0.0625	0.93269615692554	0.64184860622829	0.901378992017767
GO:0047498	calcium-dependent phospholipase A2 activity	2/1249	32/18639	0.0625	0.93269615692554	0.64184860622829	0.901378992017767
GO:0120015	sterol transfer activity	2/1249	32/18639	0.0625	0.93269615692554	0.64184860622829	0.901378992017767
GO:0140142	nucleocytoplasmic carrier activity	2/1249	32/18639	0.0625	0.93269615692554	0.64184860622829	0.901378992017767
GO:0005004	GPI-linked ephrin receptor activity	3/1249	49/18639	0.0612244897959184	0.91366154147808	0.646586266899729	0.901378992017767
GO:0005008	hepatocyte growth factor receptor activity	3/1249	49/18639	0.0612244897959184	0.91366154147808	0.646586266899729	0.901378992017767
GO:0005009	insulin receptor activity	3/1249	49/18639	0.0612244897959184	0.91366154147808	0.646586266899729	0.901378992017767
GO:0005011	macrophage colony-stimulating factor receptor activity	3/1249	49/18639	0.0612244897959184	0.91366154147808	0.646586266899729	0.901378992017767
GO:0005018	platelet-derived growth factor alpha-receptor activity	3/1249	49/18639	0.0612244897959184	0.91366154147808	0.646586266899729	0.901378992017767
GO:0005020	stem cell factor receptor activity	3/1249	49/18639	0.0612244897959184	0.91366154147808	0.646586266899729	0.901378992017767
GO:0008288	boss receptor activity	3/1249	49/18639	0.0612244897959184	0.91366154147808	0.646586266899729	0.901378992017767
GO:0036332	placental growth factor receptor activity	3/1249	49/18639	0.0612244897959184	0.91366154147808	0.646586266899729	0.901378992017767
GO:0038062	protein tyrosine kinase collagen receptor activity	3/1249	49/18639	0.0612244897959184	0.91366154147808	0.646586266899729	0.901378992017767
GO:0060175	brain-derived neurotrophic factor receptor activity	3/1249	49/18639	0.0612244897959184	0.91366154147808	0.646586266899729	0.901378992017767
GO:0004559	alpha-mannosidase activity	1/1249	15/18639	0.0666666666666667	0.994875900720576	0.646834075594519	0.901378992017767
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	1/1249	15/18639	0.0666666666666667	0.994875900720576	0.646834075594519	0.901378992017767
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	1/1249	15/18639	0.0666666666666667	0.994875900720576	0.646834075594519	0.901378992017767
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/1249	15/18639	0.0666666666666667	0.994875900720576	0.646834075594519	0.901378992017767
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/1249	15/18639	0.0666666666666667	0.994875900720576	0.646834075594519	0.901378992017767
GO:0005523	tropomyosin binding	1/1249	15/18639	0.0666666666666667	0.994875900720576	0.646834075594519	0.901378992017767
GO:0008242	omega peptidase activity	1/1249	15/18639	0.0666666666666667	0.994875900720576	0.646834075594519	0.901378992017767
GO:0015929	hexosaminidase activity	1/1249	15/18639	0.0666666666666667	0.994875900720576	0.646834075594519	0.901378992017767
GO:0016846	carbon-sulfur lyase activity	1/1249	15/18639	0.0666666666666667	0.994875900720576	0.646834075594519	0.901378992017767
GO:0031005	filamin binding	1/1249	15/18639	0.0666666666666667	0.994875900720576	0.646834075594519	0.901378992017767
GO:0034483	heparan sulfate sulfotransferase activity	1/1249	15/18639	0.0666666666666667	0.994875900720576	0.646834075594519	0.901378992017767
GO:0042809	nuclear vitamin D receptor binding	1/1249	15/18639	0.0666666666666667	0.994875900720576	0.646834075594519	0.901378992017767
GO:0047372	monoacylglycerol lipase activity	1/1249	15/18639	0.0666666666666667	0.994875900720576	0.646834075594519	0.901378992017767
GO:0048531	beta-1,3-galactosyltransferase activity	1/1249	15/18639	0.0666666666666667	0.994875900720576	0.646834075594519	0.901378992017767
GO:0016298	lipase activity	8/1249	130/18639	0.0615384615384615	0.918346985280532	0.649385663719314	0.903809151370538
GO:0008083	growth factor activity	10/1249	162/18639	0.0617283950617284	0.921181389556089	0.651718442208311	0.9059291140759
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	2/1249	33/18639	0.0606060606060606	0.904432637018706	0.658596418139928	0.909976557217374
GO:0005006	epidermal growth factor receptor activity	3/1249	50/18639	0.06	0.895388310648519	0.660186555946341	0.909976557217374
GO:0005007	fibroblast growth factor receptor activity	3/1249	50/18639	0.06	0.895388310648519	0.660186555946341	0.909976557217374
GO:0005017	platelet-derived growth factor receptor activity	3/1249	50/18639	0.06	0.895388310648519	0.660186555946341	0.909976557217374
GO:0005019	platelet-derived growth factor beta-receptor activity	3/1249	50/18639	0.06	0.895388310648519	0.660186555946341	0.909976557217374
GO:0015605	organophosphate ester transmembrane transporter activity	3/1249	50/18639	0.06	0.895388310648519	0.660186555946341	0.909976557217374
GO:0016500	protein-hormone receptor activity	4/1249	67/18639	0.0597014925373134	0.890933642436337	0.665165474851903	0.909976557217374
GO:0000062	fatty-acyl-CoA binding	1/1249	16/18639	0.0625	0.93269615692554	0.670518796362477	0.909976557217374
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	1/1249	16/18639	0.0625	0.93269615692554	0.670518796362477	0.909976557217374
GO:0004708	MAP kinase kinase activity	1/1249	16/18639	0.0625	0.93269615692554	0.670518796362477	0.909976557217374
GO:0005024	transforming growth factor beta receptor activity	1/1249	16/18639	0.0625	0.93269615692554	0.670518796362477	0.909976557217374
GO:0008296	3'-5'-DNA exonuclease activity	1/1249	16/18639	0.0625	0.93269615692554	0.670518796362477	0.909976557217374
GO:0015562	efflux transmembrane transporter activity	1/1249	16/18639	0.0625	0.93269615692554	0.670518796362477	0.909976557217374
GO:0015923	mannosidase activity	1/1249	16/18639	0.0625	0.93269615692554	0.670518796362477	0.909976557217374
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/1249	16/18639	0.0625	0.93269615692554	0.670518796362477	0.909976557217374
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/1249	16/18639	0.0625	0.93269615692554	0.670518796362477	0.909976557217374
GO:0022858	alanine transmembrane transporter activity	1/1249	16/18639	0.0625	0.93269615692554	0.670518796362477	0.909976557217374
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/1249	16/18639	0.0625	0.93269615692554	0.670518796362477	0.909976557217374
GO:0140327	flippase activity	1/1249	16/18639	0.0625	0.93269615692554	0.670518796362477	0.909976557217374
GO:0005010	insulin-like growth factor receptor activity	3/1249	51/18639	0.0588235294117647	0.877831677106391	0.673403927607415	0.909976557217374
GO:0005030	neurotrophin receptor activity	3/1249	51/18639	0.0588235294117647	0.877831677106391	0.673403927607415	0.909976557217374
GO:0016597	amino acid binding	3/1249	51/18639	0.0588235294117647	0.877831677106391	0.673403927607415	0.909976557217374
GO:0008376	acetylgalactosaminyltransferase activity	2/1249	34/18639	0.0588235294117647	0.877831677106391	0.67471006059758	0.909976557217374
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/1249	34/18639	0.0588235294117647	0.877831677106391	0.67471006059758	0.909976557217374
GO:0016758	hexosyltransferase activity	12/1249	197/18639	0.0609137055837563	0.909023665633014	0.675598880543886	0.909976557217374
GO:0005548	phospholipid transporter activity	4/1249	68/18639	0.0588235294117647	0.877831677106391	0.676586680612024	0.909976557217374
GO:0140223	general transcription initiation factor activity	4/1249	68/18639	0.0588235294117647	0.877831677106391	0.676586680612024	0.909976557217374
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	3/1249	52/18639	0.0576923076923077	0.860950298700499	0.686238627443016	0.913959495878111
GO:0000175	3'-5'-RNA exonuclease activity	2/1249	35/18639	0.0571428571428571	0.852750772046208	0.69019925069232	0.913959495878111
GO:0004623	phospholipase A2 activity	2/1249	35/18639	0.0571428571428571	0.852750772046208	0.69019925069232	0.913959495878111
GO:0005154	epidermal growth factor receptor binding	2/1249	35/18639	0.0571428571428571	0.852750772046208	0.69019925069232	0.913959495878111
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/1249	17/18639	0.0588235294117647	0.877831677106391	0.692616311442929	0.913959495878111
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/1249	17/18639	0.0588235294117647	0.877831677106391	0.692616311442929	0.913959495878111
GO:0008484	sulfuric ester hydrolase activity	1/1249	17/18639	0.0588235294117647	0.877831677106391	0.692616311442929	0.913959495878111
GO:0008569	minus-end-directed microtubule motor activity	1/1249	17/18639	0.0588235294117647	0.877831677106391	0.692616311442929	0.913959495878111
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/1249	17/18639	0.0588235294117647	0.877831677106391	0.692616311442929	0.913959495878111
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/1249	17/18639	0.0588235294117647	0.877831677106391	0.692616311442929	0.913959495878111
GO:0030548	acetylcholine receptor regulator activity	1/1249	17/18639	0.0588235294117647	0.877831677106391	0.692616311442929	0.913959495878111
GO:0031489	myosin V binding	1/1249	17/18639	0.0588235294117647	0.877831677106391	0.692616311442929	0.913959495878111
GO:0036041	long-chain fatty acid binding	1/1249	17/18639	0.0588235294117647	0.877831677106391	0.692616311442929	0.913959495878111
GO:0038191	neuropilin binding	1/1249	17/18639	0.0588235294117647	0.877831677106391	0.692616311442929	0.913959495878111
GO:0045125	bioactive lipid receptor activity	1/1249	17/18639	0.0588235294117647	0.877831677106391	0.692616311442929	0.913959495878111
GO:1901567	fatty acid derivative binding	1/1249	17/18639	0.0588235294117647	0.877831677106391	0.692616311442929	0.913959495878111
GO:0016779	nucleotidyltransferase activity	8/1249	136/18639	0.0588235294117647	0.877831677106391	0.698481703155348	0.919807351747193
GO:0038064	collagen receptor activity	3/1249	53/18639	0.0566037735849057	0.844705953441999	0.698691911514847	0.919807351747193
GO:0140299	molecular sensor activity	4/1249	71/18639	0.0563380281690141	0.840740197792036	0.709204595336295	0.930195363641313
GO:0000400	four-way junction DNA binding	1/1249	18/18639	0.0555555555555556	0.82906325060048	0.713232906170015	0.930195363641313
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/1249	18/18639	0.0555555555555556	0.82906325060048	0.713232906170015	0.930195363641313
GO:0008409	5'-3' exonuclease activity	1/1249	18/18639	0.0555555555555556	0.82906325060048	0.713232906170015	0.930195363641313
GO:0008525	phosphatidylcholine transporter activity	1/1249	18/18639	0.0555555555555556	0.82906325060048	0.713232906170015	0.930195363641313
GO:0017075	syntaxin-1 binding	1/1249	18/18639	0.0555555555555556	0.82906325060048	0.713232906170015	0.930195363641313
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/1249	18/18639	0.0555555555555556	0.82906325060048	0.713232906170015	0.930195363641313
GO:0099602	neurotransmitter receptor regulator activity	1/1249	18/18639	0.0555555555555556	0.82906325060048	0.713232906170015	0.930195363641313
GO:0008234	cysteine-type peptidase activity	11/1249	187/18639	0.0588235294117647	0.877831677106391	0.715451434950939	0.932002509557742
GO:0022829	wide pore channel activity	2/1249	37/18639	0.0540540540540541	0.806656135719386	0.719350617671869	0.935992257180025
GO:0046943	carboxylic acid transmembrane transporter activity	11/1249	188/18639	0.0585106382978723	0.873162359674974	0.721901297933055	0.93627139333407
GO:0008514	organic anion transmembrane transporter activity	16/1249	269/18639	0.0594795539033457	0.887621621460737	0.725329361322069	0.93627139333407
GO:0005342	organic acid transmembrane transporter activity	11/1249	189/18639	0.0582010582010582	0.868542453010027	0.728256436080344	0.93627139333407
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/1249	19/18639	0.0526315789473684	0.785428342674139	0.732467753932952	0.93627139333407
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/1249	19/18639	0.0526315789473684	0.785428342674139	0.732467753932952	0.93627139333407
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/1249	19/18639	0.0526315789473684	0.785428342674139	0.732467753932952	0.93627139333407
GO:0031420	alkali metal ion binding	1/1249	19/18639	0.0526315789473684	0.785428342674139	0.732467753932952	0.93627139333407
GO:0042577	lipid phosphatase activity	1/1249	19/18639	0.0526315789473684	0.785428342674139	0.732467753932952	0.93627139333407
GO:0042800	histone H3K4 methyltransferase activity	1/1249	19/18639	0.0526315789473684	0.785428342674139	0.732467753932952	0.93627139333407
GO:0042834	peptidoglycan binding	1/1249	19/18639	0.0526315789473684	0.785428342674139	0.732467753932952	0.93627139333407
GO:0099589	serotonin receptor activity	1/1249	19/18639	0.0526315789473684	0.785428342674139	0.732467753932952	0.93627139333407
GO:0120227	acyl-CoA binding	1/1249	19/18639	0.0526315789473684	0.785428342674139	0.732467753932952	0.93627139333407
GO:0005501	retinoid binding	2/1249	38/18639	0.0526315789473684	0.785428342674139	0.733038979698054	0.93627139333407
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	2/1249	38/18639	0.0526315789473684	0.785428342674139	0.733038979698054	0.93627139333407
GO:0019840	isoprenoid binding	2/1249	38/18639	0.0526315789473684	0.785428342674139	0.733038979698054	0.93627139333407
GO:0042887	amide transmembrane transporter activity	2/1249	38/18639	0.0526315789473684	0.785428342674139	0.733038979698054	0.93627139333407
GO:0019212	phosphatase inhibitor activity	3/1249	56/18639	0.0535714285714286	0.79945384879332	0.733789108091134	0.93627139333407
GO:0003684	damaged DNA binding	4/1249	74/18639	0.0540540540540541	0.806656135719386	0.739356046750676	0.942300018580873
GO:0020037	heme binding	8/1249	142/18639	0.0563380281690141	0.840740197792036	0.742937863465657	0.945787792056963
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	2/1249	39/18639	0.0512820512820513	0.765289154400443	0.746154836176115	0.947756868306128
GO:0141003	histone H2AX kinase activity	21/1249	354/18639	0.0593220338983051	0.885270928607293	0.750375961425999	0.947756868306128
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/1249	20/18639	0.05	0.746156925540432	0.750413391706193	0.947756868306128
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/1249	20/18639	0.05	0.746156925540432	0.750413391706193	0.947756868306128
GO:0015464	acetylcholine receptor activity	1/1249	20/18639	0.05	0.746156925540432	0.750413391706193	0.947756868306128
GO:0016505	peptidase activator activity involved in apoptotic process	1/1249	20/18639	0.05	0.746156925540432	0.750413391706193	0.947756868306128
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/1249	20/18639	0.05	0.746156925540432	0.750413391706193	0.947756868306128
GO:0005543	phospholipid binding	30/1249	497/18639	0.0603621730382294	0.900793069062896	0.751321198842622	0.947833620636859
GO:0019955	cytokine binding	8/1249	144/18639	0.0555555555555556	0.82906325060048	0.756699836081727	0.953544050197581
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	2/1249	40/18639	0.05	0.746156925540432	0.758713380093897	0.953932890252888
GO:0071949	FAD binding	2/1249	40/18639	0.05	0.746156925540432	0.758713380093897	0.953932890252888
GO:0140996	histone H3 kinase activity	21/1249	357/18639	0.0588235294117647	0.877831677106391	0.76351715776324	0.955955175168014
GO:0015459	potassium channel regulator activity	3/1249	59/18639	0.0508474576271186	0.758803653091965	0.765577576174255	0.955955175168014
GO:0010314	phosphatidylinositol-5-phosphate binding	1/1249	21/18639	0.0476190476190476	0.71062564337184	0.767156163807754	0.955955175168014
GO:0015125	bile acid transmembrane transporter activity	1/1249	21/18639	0.0476190476190476	0.71062564337184	0.767156163807754	0.955955175168014
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/1249	21/18639	0.0476190476190476	0.71062564337184	0.767156163807754	0.955955175168014
GO:0051428	peptide hormone receptor binding	1/1249	21/18639	0.0476190476190476	0.71062564337184	0.767156163807754	0.955955175168014
GO:0072542	protein phosphatase activator activity	1/1249	21/18639	0.0476190476190476	0.71062564337184	0.767156163807754	0.955955175168014
GO:1904047	S-adenosyl-L-methionine binding	1/1249	21/18639	0.0476190476190476	0.71062564337184	0.767156163807754	0.955955175168014
GO:0008227	G protein-coupled amine receptor activity	2/1249	41/18639	0.0487804878048781	0.727957976137007	0.770730340148895	0.95894892300653
GO:0004867	serine-type endopeptidase inhibitor activity	5/1249	95/18639	0.0526315789473684	0.785428342674139	0.771272592230453	0.95894892300653
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3/1249	60/18639	0.05	0.746156925540432	0.775463044155757	0.962557204056863
GO:0035173	histone kinase activity	21/1249	360/18639	0.0583333333333333	0.870516413130504	0.776198350406385	0.962557204056863
GO:0022804	active transmembrane transporter activity	27/1249	457/18639	0.0590809628008753	0.881673391229395	0.779663763429415	0.962557204056863
GO:0005243	gap junction channel activity	1/1249	22/18639	0.0454545454545455	0.678324477764029	0.782776636006922	0.962557204056863
GO:0008970	phospholipase A1 activity	1/1249	22/18639	0.0454545454545455	0.678324477764029	0.782776636006922	0.962557204056863
GO:0015377	chloride:monoatomic cation symporter activity	1/1249	22/18639	0.0454545454545455	0.678324477764029	0.782776636006922	0.962557204056863
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/1249	22/18639	0.0454545454545455	0.678324477764029	0.782776636006922	0.962557204056863
GO:0034062	5'-3' RNA polymerase activity	1/1249	22/18639	0.0454545454545455	0.678324477764029	0.782776636006922	0.962557204056863
GO:0097747	RNA polymerase activity	1/1249	22/18639	0.0454545454545455	0.678324477764029	0.782776636006922	0.962557204056863
GO:0140784	metal ion sensor activity	1/1249	22/18639	0.0454545454545455	0.678324477764029	0.782776636006922	0.962557204056863
GO:0008200	ion channel inhibitor activity	2/1249	43/18639	0.0465116279069767	0.694099465619007	0.793204279164682	0.968910241501735
GO:0031267	small GTPase binding	16/1249	283/18639	0.0565371024734982	0.843711011211796	0.79382552984609	0.968910241501735
GO:0042626	ATPase-coupled transmembrane transporter activity	5/1249	98/18639	0.0510204081632653	0.7613846178984	0.794097328917524	0.968910241501735
GO:0015179	L-amino acid transmembrane transporter activity	3/1249	62/18639	0.0483870967741935	0.722087347297193	0.794205925427485	0.968910241501735
GO:0008237	metallopeptidase activity	10/1249	184/18639	0.0543478260869565	0.811040136456992	0.795786607204863	0.968910241501735
GO:0000295	adenine nucleotide transmembrane transporter activity	1/1249	23/18639	0.0434782608695652	0.648832109165593	0.797349981961015	0.968910241501735
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/1249	23/18639	0.0434782608695652	0.648832109165593	0.797349981961015	0.968910241501735
GO:0004602	glutathione peroxidase activity	1/1249	23/18639	0.0434782608695652	0.648832109165593	0.797349981961015	0.968910241501735
GO:0005283	amino acid:sodium symporter activity	1/1249	23/18639	0.0434782608695652	0.648832109165593	0.797349981961015	0.968910241501735
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/1249	23/18639	0.0434782608695652	0.648832109165593	0.797349981961015	0.968910241501735
GO:0015294	solute:monoatomic cation symporter activity	6/1249	116/18639	0.0517241379310345	0.771886474696999	0.797467678662286	0.968910241501735
GO:0016248	channel inhibitor activity	2/1249	44/18639	0.0454545454545455	0.678324477764029	0.803694215339923	0.971173106291154
GO:0046906	tetrapyrrole binding	8/1249	152/18639	0.0526315789473684	0.785428342674139	0.806484747512308	0.971173106291154
GO:0015631	tubulin binding	22/1249	385/18639	0.0571428571428571	0.852750772046208	0.810519431818188	0.971173106291154
GO:0004622	lysophospholipase activity	1/1249	24/18639	0.0416666666666667	0.62179743795036	0.810946343828801	0.971173106291154
GO:0004806	triacylglycerol lipase activity	1/1249	24/18639	0.0416666666666667	0.62179743795036	0.810946343828801	0.971173106291154
GO:0005315	phosphate transmembrane transporter activity	1/1249	24/18639	0.0416666666666667	0.62179743795036	0.810946343828801	0.971173106291154
GO:0015295	solute:proton symporter activity	1/1249	24/18639	0.0416666666666667	0.62179743795036	0.810946343828801	0.971173106291154
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/1249	24/18639	0.0416666666666667	0.62179743795036	0.810946343828801	0.971173106291154
GO:0019957	C-C chemokine binding	1/1249	24/18639	0.0416666666666667	0.62179743795036	0.810946343828801	0.971173106291154
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/1249	24/18639	0.0416666666666667	0.62179743795036	0.810946343828801	0.971173106291154
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/1249	24/18639	0.0416666666666667	0.62179743795036	0.810946343828801	0.971173106291154
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/1249	24/18639	0.0416666666666667	0.62179743795036	0.810946343828801	0.971173106291154
GO:0004715	non-membrane spanning protein tyrosine kinase activity	2/1249	45/18639	0.0444444444444444	0.663250600480384	0.813708277837087	0.971173106291154
GO:0141110	transporter inhibitor activity	2/1249	45/18639	0.0444444444444444	0.663250600480384	0.813708277837087	0.971173106291154
GO:0044325	transmembrane transporter binding	7/1249	136/18639	0.0514705882352941	0.768102717468092	0.813748565040531	0.971173106291154
GO:0008238	exopeptidase activity	5/1249	102/18639	0.0490196078431373	0.731526397588659	0.821704871226301	0.971173106291154
GO:0030276	clathrin binding	2/1249	46/18639	0.0434782608695652	0.648832109165593	0.8232630797236	0.971173106291154
GO:0004175	endopeptidase activity	23/1249	405/18639	0.0567901234567901	0.847486878391602	0.823612906964746	0.971173106291154
GO:0005537	D-mannose binding	1/1249	25/18639	0.04	0.596925540432346	0.823631168784902	0.971173106291154
GO:0008483	transaminase activity	1/1249	25/18639	0.04	0.596925540432346	0.823631168784902	0.971173106291154
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/1249	25/18639	0.04	0.596925540432346	0.823631168784902	0.971173106291154
GO:0015662	P-type ion transporter activity	1/1249	25/18639	0.04	0.596925540432346	0.823631168784902	0.971173106291154
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/1249	25/18639	0.04	0.596925540432346	0.823631168784902	0.971173106291154
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/1249	25/18639	0.04	0.596925540432346	0.823631168784902	0.971173106291154
GO:0019211	phosphatase activator activity	1/1249	25/18639	0.04	0.596925540432346	0.823631168784902	0.971173106291154
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/1249	25/18639	0.04	0.596925540432346	0.823631168784902	0.971173106291154
GO:0019707	protein-cysteine S-acyltransferase activity	1/1249	25/18639	0.04	0.596925540432346	0.823631168784902	0.971173106291154
GO:0140358	P-type transmembrane transporter activity	1/1249	25/18639	0.04	0.596925540432346	0.823631168784902	0.971173106291154
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/1249	26/18639	0.0384615384615385	0.573966865800333	0.835465523044473	0.979964277030153
GO:0004529	DNA exonuclease activity	1/1249	26/18639	0.0384615384615385	0.573966865800333	0.835465523044473	0.979964277030153
GO:0005112	Notch binding	1/1249	26/18639	0.0384615384615385	0.573966865800333	0.835465523044473	0.979964277030153
GO:0015216	purine nucleotide transmembrane transporter activity	1/1249	26/18639	0.0384615384615385	0.573966865800333	0.835465523044473	0.979964277030153
GO:0120014	phospholipid transfer activity	1/1249	26/18639	0.0384615384615385	0.573966865800333	0.835465523044473	0.979964277030153
GO:0003777	microtubule motor activity	3/1249	68/18639	0.0441176470588235	0.658373757829793	0.84273187320358	0.987452320539063
GO:0000149	SNARE binding	5/1249	106/18639	0.0471698113207547	0.703921627868332	0.846245796328806	0.988768940191161
GO:0004497	monooxygenase activity	5/1249	106/18639	0.0471698113207547	0.703921627868332	0.846245796328806	0.988768940191161
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	1/1249	27/18639	0.037037037037037	0.552708833733654	0.846506384900029	0.988768940191161
GO:0004677	DNA-dependent protein kinase activity	13/1249	246/18639	0.0528455284552846	0.788621140815091	0.847701093010989	0.98913193230375
GO:0005242	inward rectifier potassium channel activity	1/1249	28/18639	0.0357142857142857	0.53296923252888	0.856806918172104	0.991403151587226
GO:0016866	intramolecular transferase activity	1/1249	28/18639	0.0357142857142857	0.53296923252888	0.856806918172104	0.991403151587226
GO:0045499	chemorepellent activity	1/1249	28/18639	0.0357142857142857	0.53296923252888	0.856806918172104	0.991403151587226
GO:0050698	proteoglycan sulfotransferase activity	1/1249	28/18639	0.0357142857142857	0.53296923252888	0.856806918172104	0.991403151587226
GO:0051393	alpha-actinin binding	1/1249	28/18639	0.0357142857142857	0.53296923252888	0.856806918172104	0.991403151587226
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	1/1249	28/18639	0.0357142857142857	0.53296923252888	0.856806918172104	0.991403151587226
GO:0005496	steroid binding	5/1249	108/18639	0.0462962962962963	0.690886042167067	0.857429585576617	0.991403151587226
GO:0008194	UDP-glycosyltransferase activity	7/1249	145/18639	0.0482758620689655	0.720427376383866	0.860916341976383	0.991403151587226
GO:0035091	phosphatidylinositol binding	15/1249	284/18639	0.0528169014084507	0.788193935430034	0.862562357340481	0.991403151587226
GO:0015293	symporter activity	7/1249	146/18639	0.0479452054794521	0.715492942299045	0.865498276194487	0.991403151587226
GO:0005416	amino acid:monoatomic cation symporter activity	1/1249	29/18639	0.0344827586206897	0.514590983131333	0.866416727381874	0.991403151587226
GO:0016417	S-acyltransferase activity	1/1249	29/18639	0.0344827586206897	0.514590983131333	0.866416727381874	0.991403151587226
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	1/1249	29/18639	0.0344827586206897	0.514590983131333	0.866416727381874	0.991403151587226
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	4/1249	91/18639	0.043956043956044	0.655962132343237	0.866937856044721	0.991403151587226
GO:0052689	carboxylic ester hydrolase activity	4/1249	92/18639	0.0434782608695652	0.648832109165593	0.872409301155844	0.991403151587226
GO:0016798	hydrolase activity, acting on glycosyl bonds	6/1249	130/18639	0.0461538461538462	0.688760238960399	0.87522466780986	0.991403151587226
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	3/1249	73/18639	0.0410958904109589	0.613279664827753	0.87527384172091	0.991403151587226
GO:0001965	G-protein alpha-subunit binding	1/1249	30/18639	0.0333333333333333	0.497437950360288	0.875382095866562	0.991403151587226
GO:0016769	transferase activity, transferring nitrogenous groups	1/1249	30/18639	0.0333333333333333	0.497437950360288	0.875382095866562	0.991403151587226
GO:0031210	phosphatidylcholine binding	1/1249	30/18639	0.0333333333333333	0.497437950360288	0.875382095866562	0.991403151587226
GO:0051721	protein phosphatase 2A binding	1/1249	30/18639	0.0333333333333333	0.497437950360288	0.875382095866562	0.991403151587226
GO:0070566	adenylyltransferase activity	1/1249	30/18639	0.0333333333333333	0.497437950360288	0.875382095866562	0.991403151587226
GO:0016874	ligase activity	8/1249	167/18639	0.0479041916167665	0.714880886745324	0.878430688533314	0.991403151587226
GO:0004864	protein phosphatase inhibitor activity	2/1249	53/18639	0.0377358490566038	0.563137302294666	0.87865035495863	0.991403151587226
GO:0005246	calcium channel regulator activity	2/1249	53/18639	0.0377358490566038	0.563137302294666	0.87865035495863	0.991403151587226
GO:0008146	sulfotransferase activity	2/1249	53/18639	0.0377358490566038	0.563137302294666	0.87865035495863	0.991403151587226
GO:0016251	RNA polymerase II general transcription initiation factor activity	2/1249	53/18639	0.0377358490566038	0.563137302294666	0.87865035495863	0.991403151587226
GO:1901505	carbohydrate derivative transmembrane transporter activity	2/1249	53/18639	0.0377358490566038	0.563137302294666	0.87865035495863	0.991403151587226
GO:0005201	extracellular matrix structural constituent	8/1249	168/18639	0.0476190476190476	0.71062564337184	0.882322277735842	0.991403151587226
GO:0016247	channel regulator activity	8/1249	168/18639	0.0476190476190476	0.71062564337184	0.882322277735842	0.991403151587226
GO:0042562	hormone binding	4/1249	94/18639	0.0425531914893617	0.635027170672708	0.882771604654104	0.991403151587226
GO:0005452	solute:inorganic anion antiporter activity	1/1249	31/18639	0.032258064516129	0.481391564864795	0.883746207976975	0.991403151587226
GO:0005179	hormone activity	6/1249	132/18639	0.0454545454545455	0.678324477764029	0.883979833961374	0.991403151587226
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	2/1249	54/18639	0.037037037037037	0.552708833733654	0.885107447250743	0.991403151587226
GO:0141108	transporter regulator activity	8/1249	170/18639	0.0470588235294118	0.702265341685113	0.889796362300407	0.991403151587226
GO:0015106	bicarbonate transmembrane transporter activity	1/1249	32/18639	0.03125	0.46634807846277	0.891549356420481	0.991403151587226
GO:0004896	cytokine receptor activity	4/1249	96/18639	0.0416666666666667	0.62179743795036	0.892393757734204	0.991403151587226
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	12/1249	243/18639	0.0493827160493827	0.736945111644871	0.896145494625869	0.991403151587226
GO:0019239	deaminase activity	1/1249	33/18639	0.0303030303030303	0.452216318509353	0.898829135741748	0.991403151587226
GO:0019956	chemokine binding	1/1249	33/18639	0.0303030303030303	0.452216318509353	0.898829135741748	0.991403151587226
GO:0004676	3-phosphoinositide-dependent protein kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0004711	ribosomal protein S6 kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0035175	histone H3S10 kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0035979	histone H2AXS139 kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0044022	histone H3S28 kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0044023	histone H4S1 kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0044024	histone H2AS1 kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0044025	histone H2BS14 kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0072354	histone H3T3 kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0072371	histone H2AS121 kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0072518	Rho-dependent protein serine/threonine kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0140823	histone H2BS36 kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0140855	histone H3S57 kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0140995	histone H2A kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0140997	histone H4 kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0140998	histone H2B kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:1990244	histone H2AT120 kinase activity	12/1249	245/18639	0.0489795918367347	0.730929233182464	0.901905815336263	0.991403151587226
GO:0015932	nucleobase-containing compound transmembrane transporter activity	2/1249	57/18639	0.0350877192982456	0.523618895116093	0.902615923390129	0.991403151587226
GO:0140857	histone H3T45 kinase activity	12/1249	246/18639	0.0487804878048781	0.727957976137007	0.904685544686277	0.991403151587226
GO:0008175	tRNA methyltransferase activity	1/1249	34/18639	0.0294117647058824	0.438915838553196	0.905620622867329	0.991403151587226
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1/1249	34/18639	0.0294117647058824	0.438915838553196	0.905620622867329	0.991403151587226
GO:0015370	solute:sodium symporter activity	3/1249	79/18639	0.0379746835443038	0.566701462435771	0.906336349060789	0.991403151587226
GO:0035402	histone H3T11 kinase activity	12/1249	247/18639	0.048582995951417	0.725010777853052	0.907399690802294	0.991403151587226
GO:0035403	histone H3T6 kinase activity	12/1249	247/18639	0.048582995951417	0.725010777853052	0.907399690802294	0.991403151587226
GO:0004679	AMP-activated protein kinase activity	12/1249	248/18639	0.0483870967741935	0.722087347297193	0.910049288505331	0.991403151587226
GO:0140101	catalytic activity, acting on a tRNA	6/1249	139/18639	0.0431654676258993	0.644164252265122	0.910636173695774	0.991403151587226
GO:0005343	organic acid:sodium symporter activity	1/1249	35/18639	0.0285714285714286	0.426375386023104	0.911956545578358	0.991403151587226
GO:0061631	ubiquitin conjugating enzyme activity	1/1249	35/18639	0.0285714285714286	0.426375386023104	0.911956545578358	0.991403151587226
GO:0140566	histone reader activity	1/1249	35/18639	0.0285714285714286	0.426375386023104	0.911956545578358	0.991403151587226
GO:0015101	organic cation transmembrane transporter activity	3/1249	81/18639	0.037037037037037	0.552708833733654	0.915019752538905	0.991403151587226
GO:0004190	aspartic-type endopeptidase activity	1/1249	36/18639	0.0277777777777778	0.41453162530024	0.917867439717932	0.991403151587226
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/1249	36/18639	0.0277777777777778	0.41453162530024	0.917867439717932	0.991403151587226
GO:0005484	SNAP receptor activity	1/1249	36/18639	0.0277777777777778	0.41453162530024	0.917867439717932	0.991403151587226
GO:0016409	palmitoyltransferase activity	1/1249	36/18639	0.0277777777777778	0.41453162530024	0.917867439717932	0.991403151587226
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	1/1249	36/18639	0.0277777777777778	0.41453162530024	0.917867439717932	0.991403151587226
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	1/1249	36/18639	0.0277777777777778	0.41453162530024	0.917867439717932	0.991403151587226
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	1/1249	36/18639	0.0277777777777778	0.41453162530024	0.917867439717932	0.991403151587226
GO:0004866	endopeptidase inhibitor activity	7/1249	161/18639	0.0434782608695652	0.648832109165593	0.920497977796749	0.992568904511333
GO:0005253	monoatomic anion channel activity	4/1249	103/18639	0.0388349514563107	0.579539359643054	0.92082073908929	0.992568904511333
GO:0030280	structural constituent of skin epidermis	1/1249	37/18639	0.027027027027027	0.403328067859693	0.923381795885878	0.992568904511333
GO:0030551	cyclic nucleotide binding	1/1249	37/18639	0.027027027027027	0.403328067859693	0.923381795885878	0.992568904511333
GO:0070001	aspartic-type peptidase activity	1/1249	37/18639	0.027027027027027	0.403328067859693	0.923381795885878	0.992568904511333
GO:0000146	microfilament motor activity	1/1249	38/18639	0.0263157894736842	0.39271417133707	0.928526196323387	0.994410416897108
GO:0005507	copper ion binding	2/1249	63/18639	0.0317460317460317	0.47375042891456	0.930407239622584	0.994410416897108
GO:1901682	sulfur compound transmembrane transporter activity	2/1249	63/18639	0.0317460317460317	0.47375042891456	0.930407239622584	0.994410416897108
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	1/1249	39/18639	0.0256410256410256	0.382644577200222	0.933325442643052	0.994410416897108
GO:0008017	microtubule binding	13/1249	276/18639	0.0471014492753623	0.702901451596059	0.933328811263813	0.994410416897108
GO:0004536	DNA nuclease activity	2/1249	64/18639	0.03125	0.46634807846277	0.934238929463555	0.994410416897108
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/1249	40/18639	0.025	0.373078462770216	0.937802675016107	0.994410416897108
GO:0050997	quaternary ammonium group binding	1/1249	40/18639	0.025	0.373078462770216	0.937802675016107	0.994410416897108
GO:0061791	GTPase motor activity	1/1249	40/18639	0.025	0.373078462770216	0.937802675016107	0.994410416897108
GO:0071855	neuropeptide receptor binding	1/1249	40/18639	0.025	0.373078462770216	0.937802675016107	0.994410416897108
GO:1990606	membrane scission GTPase motor activity	1/1249	40/18639	0.025	0.373078462770216	0.937802675016107	0.994410416897108
GO:0030414	peptidase inhibitor activity	7/1249	169/18639	0.0414201183431953	0.618118163169589	0.940927257621995	0.994410416897108
GO:0005516	calmodulin binding	9/1249	207/18639	0.0434782608695652	0.648832109165593	0.94126238145101	0.994410416897108
GO:0008235	metalloexopeptidase activity	2/1249	66/18639	0.0303030303030303	0.452216318509353	0.941310457713432	0.994410416897108
GO:0004812	aminoacyl-tRNA ligase activity	1/1249	41/18639	0.024390243902439	0.363978988068504	0.941979483387788	0.994410416897108
GO:0016875	ligase activity, forming carbon-oxygen bonds	1/1249	41/18639	0.024390243902439	0.363978988068504	0.941979483387788	0.994410416897108
GO:0017080	sodium channel regulator activity	1/1249	41/18639	0.024390243902439	0.363978988068504	0.941979483387788	0.994410416897108
GO:0061650	ubiquitin-like protein conjugating enzyme activity	1/1249	41/18639	0.024390243902439	0.363978988068504	0.941979483387788	0.994410416897108
GO:0140828	metal cation:monoatomic cation antiporter activity	1/1249	41/18639	0.024390243902439	0.363978988068504	0.941979483387788	0.994410416897108
GO:0004520	DNA endonuclease activity	1/1249	42/18639	0.0238095238095238	0.35531282168592	0.945876011253615	0.996643367789826
GO:0016859	cis-trans isomerase activity	1/1249	42/18639	0.0238095238095238	0.35531282168592	0.945876011253615	0.996643367789826
GO:0005245	voltage-gated calcium channel activity	1/1249	43/18639	0.0232558139534884	0.347049732809503	0.949511052493828	0.999532330894255
GO:0043178	alcohol binding	3/1249	92/18639	0.0326086956521739	0.486624081874195	0.950946992868327	0.99980343021503
GO:0016790	thiolester hydrolase activity	1/1249	44/18639	0.0227272727272727	0.339162238882015	0.952902141729965	0.99980343021503
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/1249	44/18639	0.0227272727272727	0.339162238882015	0.952902141729965	0.99980343021503
GO:0016782	transferase activity, transferring sulphur-containing groups	2/1249	70/18639	0.0285714285714286	0.426375386023104	0.953342502269381	0.99980343021503
GO:0004180	carboxypeptidase activity	1/1249	46/18639	0.0217391304347826	0.324416054582797	0.959016806612466	0.999966464104387
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/1249	46/18639	0.0217391304347826	0.324416054582797	0.959016806612466	0.999966464104387
GO:0099106	ion channel regulator activity	6/1249	160/18639	0.0375	0.559617694155324	0.961308136213051	0.999966464104387
GO:0099095	ligand-gated monoatomic anion channel activity	1/1249	47/18639	0.0212765957446809	0.317513585336354	0.96176988618763	0.999966464104387
GO:0032266	phosphatidylinositol-3-phosphate binding	1/1249	48/18639	0.0208333333333333	0.31089871897518	0.964338163519367	0.999966464104387
GO:0015171	amino acid transmembrane transporter activity	3/1249	102/18639	0.0294117647058824	0.438915838553196	0.970779083475835	0.999966464104387
GO:0016835	carbon-oxygen lyase activity	2/1249	79/18639	0.0253164556962025	0.377800974957181	0.972384244512304	0.999966464104387
GO:0008509	monoatomic anion transmembrane transporter activity	5/1249	149/18639	0.0335570469798658	0.50077646009425	0.97464339519195	0.999966464104387
GO:0017046	peptide hormone binding	1/1249	53/18639	0.0188679245283019	0.281568651147333	0.974813429751274	0.999966464104387
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/1249	53/18639	0.0188679245283019	0.281568651147333	0.974813429751274	0.999966464104387
GO:0015485	cholesterol binding	1/1249	54/18639	0.0185185185185185	0.276354416866827	0.976505995458832	0.999966464104387
GO:0050661	NADP binding	1/1249	54/18639	0.0185185185185185	0.276354416866827	0.976505995458832	0.999966464104387
GO:0005254	chloride channel activity	2/1249	83/18639	0.0240963855421687	0.35959369905563	0.978196551648794	0.999966464104387
GO:0004843	cysteine-type deubiquitinase activity	3/1249	108/18639	0.0277777777777778	0.41453162530024	0.978739668359018	0.999966464104387
GO:0003774	cytoskeletal motor activity	5/1249	153/18639	0.0326797385620915	0.487684265059106	0.978895691197597	0.999966464104387
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/1249	56/18639	0.0178571428571429	0.26648461626444	0.979557781291118	0.999966464104387
GO:0015297	antiporter activity	4/1249	135/18639	0.0296296296296296	0.442167066986923	0.98262407335939	0.999966464104387
GO:0099094	ligand-gated monoatomic cation channel activity	4/1249	136/18639	0.0294117647058824	0.438915838553196	0.983469970935536	0.999966464104387
GO:0101005	deubiquitinase activity	3/1249	115/18639	0.0260869565217391	0.389299265499356	0.985418919228462	0.999966464104387
GO:0070851	growth factor receptor binding	4/1249	139/18639	0.0287769784172662	0.429442834843414	0.985779593072137	0.999966464104387
GO:0015291	secondary active transmembrane transporter activity	11/1249	287/18639	0.0383275261324042	0.571966981250506	0.986837158211943	0.999966464104387
GO:0015081	sodium ion transmembrane transporter activity	5/1249	164/18639	0.0304878048780488	0.454973735085629	0.987402005137682	0.999966464104387
GO:0022824	transmitter-gated monoatomic ion channel activity	1/1249	63/18639	0.0158730158730159	0.23687521445728	0.987440469178567	0.999966464104387
GO:0022835	transmitter-gated channel activity	1/1249	63/18639	0.0158730158730159	0.23687521445728	0.987440469178567	0.999966464104387
GO:0015103	inorganic anion transmembrane transporter activity	5/1249	165/18639	0.0303030303030303	0.452216318509353	0.987988463206151	0.999966464104387
GO:0015108	chloride transmembrane transporter activity	3/1249	121/18639	0.0247933884297521	0.369995169689471	0.989496092015989	0.999966464104387
GO:0030594	neurotransmitter receptor activity	2/1249	97/18639	0.0206185567010309	0.307693577542446	0.990589021668178	0.999966464104387
GO:0032934	sterol binding	1/1249	68/18639	0.0147058823529412	0.219457919276598	0.991132270735441	0.999966464104387
GO:0030527	structural constituent of chromatin	2/1249	98/18639	0.0204081632653061	0.30455384715936	0.991143319787718	0.999966464104387
GO:0098960	postsynaptic neurotransmitter receptor activity	1/1249	69/18639	0.0144927536231884	0.216277369721864	0.991728673398272	0.999966464104387
GO:0019783	ubiquitin-like protein peptidase activity	3/1249	127/18639	0.0236220472440945	0.352515082932488	0.992463354333107	0.999966464104387
GO:0004252	serine-type endopeptidase activity	5/1249	176/18639	0.0284090909090909	0.423952798602518	0.992945304252847	0.999966464104387
GO:0022834	ligand-gated channel activity	5/1249	188/18639	0.0265957446808511	0.396891981670443	0.996111480115937	0.999966464104387
GO:0008236	serine-type peptidase activity	5/1249	194/18639	0.0257731958762887	0.384616971928058	0.99712861335147	0.999966464104387
GO:0017171	serine hydrolase activity	5/1249	198/18639	0.0252525252525253	0.376846932091127	0.997658557741345	0.999966464104387
GO:0022832	voltage-gated channel activity	4/1249	175/18639	0.0228571428571429	0.341100308818483	0.997840154120525	0.999966464104387
GO:0008528	G protein-coupled peptide receptor activity	2/1249	122/18639	0.0163934426229508	0.244641614931289	0.99798227571064	0.999966464104387
GO:0001653	peptide receptor activity	2/1249	128/18639	0.015625	0.233174039231385	0.998613965732864	0.999966464104387
GO:0015276	ligand-gated monoatomic ion channel activity	4/1249	186/18639	0.021505376344086	0.320927709909863	0.998814794953059	0.999966464104387
GO:0005262	calcium channel activity	2/1249	131/18639	0.0152671755725191	0.227834175737537	0.998852079492537	0.999966464104387
GO:0015079	potassium ion transmembrane transporter activity	3/1249	160/18639	0.01875	0.279808847077662	0.998855602583106	0.999966464104387
GO:0005249	voltage-gated potassium channel activity	1/1249	98/18639	0.0102040816326531	0.15227692357968	0.998903621669272	0.999966464104387
GO:0005261	monoatomic cation channel activity	10/1249	341/18639	0.0293255131964809	0.437628695331632	0.999402951256469	0.999966464104387
GO:0022843	voltage-gated monoatomic cation channel activity	2/1249	143/18639	0.013986013986014	0.208715223927394	0.999462322445128	0.999966464104387
GO:0005244	voltage-gated monoatomic ion channel activity	3/1249	173/18639	0.0173410404624277	0.258782748742346	0.999467441436991	0.999966464104387
GO:0015085	calcium ion transmembrane transporter activity	2/1249	147/18639	0.0136054421768707	0.20303589810624	0.999583047957718	0.999966464104387
GO:0005267	potassium channel activity	1/1249	124/18639	0.00806451612903226	0.120347891216199	0.999821382520037	0.999966464104387
GO:0045182	translation regulator activity	9/1249	356/18639	0.0252808988764045	0.377270355610331	0.999898608116973	0.999966464104387
GO:0005216	monoatomic ion channel activity	13/1249	448/18639	0.0290178571428571	0.433037501429715	0.999903548338702	0.999966464104387
GO:0046873	metal ion transmembrane transporter activity	13/1249	450/18639	0.0288888888888889	0.43111289031225	0.999911777474761	0.999966464104387
GO:0022836	gated channel activity	7/1249	318/18639	0.0220125786163522	0.328496759671888	0.999940216250112	0.999966464104387
GO:0030371	translation repressor activity	7/1249	329/18639	0.0212765957446809	0.317513585336354	0.999966464104387	0.999966464104387