ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0061134 peptidase regulator activity 15/250 226/18639 0.0663716814159292 4.94840707964602 4.24403392972605e-07 0.000274164591860303 GO:0061135 endopeptidase regulator activity 12/250 184/18639 0.0652173913043478 4.86234782608696 7.4056891184536e-06 0.00239203758526051 GO:0004866 endopeptidase inhibitor activity 10/250 161/18639 0.062111801242236 4.63080745341615 6.49493923640545e-05 0.0117601413295813 GO:0140416 transcription regulator inhibitor activity 5/250 33/18639 0.151515151515152 11.2963636363636 7.2818212567067e-05 0.0117601413295813 GO:0030414 peptidase inhibitor activity 10/250 169/18639 0.0591715976331361 4.41159763313609 9.7419280643814e-05 0.0125865710591808 GO:0004867 serine-type endopeptidase inhibitor activity 7/250 95/18639 0.0736842105263158 5.4936 0.000290983422432322 0.0313292151485467 GO:0042608 T cell receptor binding 3/250 11/18639 0.272727272727273 20.3334545454545 0.00036328254784781 0.0333316436480686 GO:0005179 hormone activity 8/250 132/18639 0.0606060606060606 4.51854545454546 0.0004127757727315 0.0333316436480686 GO:0045296 cadherin binding 13/250 334/18639 0.0389221556886228 2.90188023952096 0.000606373901365204 0.0392525213505183 GO:0003735 structural constituent of ribosome 9/250 175/18639 0.0514285714285714 3.83430857142857 0.000607624169512667 0.0392525213505183 GO:0020037 heme binding 8/250 142/18639 0.0563380281690141 4.20033802816901 0.00067066647473708 0.0393864129709231 GO:0016853 isomerase activity 9/250 180/18639 0.05 3.7278 0.000743492982561934 0.0400247055612508 GO:0004601 peroxidase activity 5/250 57/18639 0.087719298245614 6.54 0.000989154111043554 0.0425172896982775 GO:0016504 peptidase activator activity 5/250 57/18639 0.087719298245614 6.54 0.000989154111043554 0.0425172896982775 GO:0046906 tetrapyrrole binding 8/250 152/18639 0.0526315789473684 3.924 0.00104519615960695 0.0425172896982775 GO:0016209 antioxidant activity 6/250 86/18639 0.0697674418604651 5.20158139534884 0.00105305980676848 0.0425172896982775 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 5/250 59/18639 0.0847457627118644 6.31830508474576 0.00115731625986731 0.0439780178749577 GO:0051082 unfolded protein binding 7/250 121/18639 0.0578512396694215 4.31315702479339 0.00123957484030717 0.0444869637132462 GO:0030246 carbohydrate binding 11/250 280/18639 0.0392857142857143 2.92898571428571 0.00146296599143466 0.0496834843607382 GO:0004857 enzyme inhibitor activity 14/250 416/18639 0.0336538461538462 2.50909615384615 0.00153818837030149 0.0496834843607382 GO:1901611 phosphatidylglycerol binding 3/250 18/18639 0.166666666666667 12.426 0.00167607404798144 0.0515592302379051 GO:1990841 promoter-specific chromatin binding 5/250 68/18639 0.0735294117647059 5.48205882352941 0.00218596079926146 0.0641877580146775 GO:0051428 peptide hormone receptor binding 3/250 21/18639 0.142857142857143 10.6508571428571 0.0026519928454206 0.0744864077452916 GO:0005125 cytokine activity 9/250 234/18639 0.0384615384615385 2.86753846153846 0.00444686902356007 0.113855792274792 GO:0005006 epidermal growth factor receptor activity 4/250 50/18639 0.08 5.96448 0.00448673208586884 0.113855792274792 GO:0015294 solute:monoatomic cation symporter activity 6/250 116/18639 0.0517241379310345 3.85634482758621 0.00477015017825196 0.113855792274792 GO:0003743 translation initiation factor activity 4/250 51/18639 0.0784313725490196 5.84752941176471 0.00481817252059617 0.113855792274792 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/250 26/18639 0.115384615384615 8.60261538461538 0.00493492598095072 0.113855792274792 GO:0008135 translation factor activity, RNA binding 5/250 83/18639 0.0602409638554217 4.49132530120482 0.00517909020858125 0.114559192413126 GO:0180051 translation factor activity 5/250 84/18639 0.0595238095238095 4.43785714285714 0.00544796437571782 0.114559192413126 GO:0023026 MHC class II protein complex binding 3/250 27/18639 0.111111111111111 8.284 0.00549742254614073 0.114559192413126 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 14/250 484/18639 0.0289256198347107 2.15657851239669 0.00594245097582158 0.119963229074398 GO:0001216 DNA-binding transcription activator activity 14/250 491/18639 0.0285132382892057 2.12583299389002 0.00671120346271014 0.121300052721525 GO:0170055 lipid transmembrane transporter activity 4/250 56/18639 0.0714285714285714 5.32542857142857 0.00672289381528407 0.121300052721525 GO:0003712 transcription coregulator activity 14/250 495/18639 0.0282828282828283 2.10865454545455 0.00718500316704951 0.121300052721525 GO:0008106 alcohol dehydrogenase (NADP+) activity 3/250 30/18639 0.1 7.4556 0.00740891383469863 0.121300052721525 GO:0004090 carbonyl reductase (NADPH) activity 2/250 10/18639 0.2 14.9112 0.00751083917780344 0.121300052721525 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/250 10/18639 0.2 14.9112 0.00751083917780344 0.121300052721525 GO:0031720 haptoglobin binding 2/250 10/18639 0.2 14.9112 0.00751083917780344 0.121300052721525 GO:0032395 MHC class II receptor activity 2/250 10/18639 0.2 14.9112 0.00751083917780344 0.121300052721525 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/250 60/18639 0.0666666666666667 4.9704 0.0085629837119096 0.130623857149758 GO:0071813 lipoprotein particle binding 3/250 32/18639 0.09375 6.989625 0.00887540676403818 0.130623857149758 GO:0071814 protein-lipid complex binding 3/250 32/18639 0.09375 6.989625 0.00887540676403818 0.130623857149758 GO:0015217 ADP transmembrane transporter activity 2/250 11/18639 0.181818181818182 13.5556363636364 0.00909918509557135 0.130623857149758 GO:0048185 activin binding 2/250 11/18639 0.181818181818182 13.5556363636364 0.00909918509557135 0.130623857149758 GO:0051087 protein-folding chaperone binding 6/250 134/18639 0.0447761194029851 3.33832835820896 0.00946917392102707 0.132980138108337 GO:0002020 protease binding 6/250 136/18639 0.0441176470588235 3.28923529411765 0.0101422968014417 0.139402632632582 GO:0051427 hormone receptor binding 3/250 34/18639 0.0882352941176471 6.57847058823529 0.010499968042975 0.141312069911705 GO:0004033 aldo-keto reductase (NADPH) activity 3/250 36/18639 0.0833333333333333 6.213 0.0122855948033447 0.157508537401641 GO:0008035 high-density lipoprotein particle binding 2/250 13/18639 0.153846153846154 11.4701538461538 0.0126787057970361 0.157508537401641 GO:0071837 HMG box domain binding 2/250 13/18639 0.153846153846154 11.4701538461538 0.0126787057970361 0.157508537401641 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/250 13/18639 0.153846153846154 11.4701538461538 0.0126787057970361 0.157508537401641 GO:0023023 MHC protein complex binding 3/250 37/18639 0.0810810810810811 6.04508108108108 0.0132395804142352 0.160411504538157 GO:0015293 symporter activity 6/250 146/18639 0.0410958904109589 3.06394520547945 0.0140246694787864 0.160411504538157 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/250 70/18639 0.0571428571428571 4.26034285714286 0.0145197396281578 0.160411504538157 GO:0097110 scaffold protein binding 4/250 70/18639 0.0571428571428571 4.26034285714286 0.0145197396281578 0.160411504538157 GO:0005344 oxygen carrier activity 2/250 14/18639 0.142857142857143 10.6508571428571 0.0146621744126909 0.160411504538157 GO:0005347 ATP transmembrane transporter activity 2/250 14/18639 0.142857142857143 10.6508571428571 0.0146621744126909 0.160411504538157 GO:1901612 cardiolipin binding 2/250 14/18639 0.142857142857143 10.6508571428571 0.0146621744126909 0.160411504538157 GO:0140297 DNA-binding transcription factor binding 13/250 488/18639 0.0266393442622951 1.98612295081967 0.0148989013502933 0.160411504538157 GO:0015291 secondary active transmembrane transporter activity 9/250 287/18639 0.0313588850174216 2.33799303135888 0.0157153517034035 0.166428150826207 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/250 40/18639 0.075 5.5917 0.0163490927043878 0.167662157563385 GO:0004222 metalloendopeptidase activity 5/250 110/18639 0.0454545454545455 3.38890909090909 0.016350953446584 0.167662157563385 GO:0050780 dopamine receptor binding 2/250 15/18639 0.133333333333333 9.9408 0.0167697751912079 0.169269918336254 GO:0001530 lipopolysaccharide binding 3/250 41/18639 0.0731707317073171 5.45531707317073 0.0174687187360499 0.171281045222522 GO:0005200 structural constituent of cytoskeleton 5/250 112/18639 0.0446428571428571 3.32839285714286 0.0175446033736245 0.171281045222522 GO:0003725 double-stranded RNA binding 4/250 75/18639 0.0533333333333333 3.97632 0.0182815555312667 0.171281045222522 GO:0044183 protein folding chaperone 4/250 75/18639 0.0533333333333333 3.97632 0.0182815555312667 0.171281045222522 GO:0016859 cis-trans isomerase activity 3/250 42/18639 0.0714285714285714 5.32542857142857 0.0186301291849103 0.171281045222522 GO:0033218 amide binding 8/250 247/18639 0.0323886639676113 2.41476923076923 0.018649859885312 0.171281045222522 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/250 16/18639 0.125 9.3195 0.0189978490996456 0.171281045222522 GO:0001221 transcription coregulator binding 5/250 115/18639 0.0434782608695652 3.2415652173913 0.0194409936172199 0.171281045222522 GO:0009055 electron transfer activity 5/250 116/18639 0.0431034482758621 3.21362068965517 0.020101842420777 0.171281045222522 GO:0019199 transmembrane receptor protein kinase activity 4/250 78/18639 0.0512820512820513 3.82338461538462 0.0208033767872336 0.171281045222522 GO:0004175 endopeptidase activity 11/250 405/18639 0.0271604938271605 2.02497777777778 0.0212383595090438 0.171281045222522 GO:0008429 phosphatidylethanolamine binding 2/250 17/18639 0.117647058823529 8.77129411764706 0.0213428122422852 0.171281045222522 GO:0016018 cyclosporin A binding 2/250 17/18639 0.117647058823529 8.77129411764706 0.0213428122422852 0.171281045222522 GO:0030169 low-density lipoprotein particle binding 2/250 17/18639 0.117647058823529 8.77129411764706 0.0213428122422852 0.171281045222522 GO:1990226 histone methyltransferase binding 2/250 17/18639 0.117647058823529 8.77129411764706 0.0213428122422852 0.171281045222522 GO:0015370 solute:sodium symporter activity 4/250 79/18639 0.0506329113924051 3.77498734177215 0.0216890453509828 0.171281045222522 GO:0016835 carbon-oxygen lyase activity 4/250 79/18639 0.0506329113924051 3.77498734177215 0.0216890453509828 0.171281045222522 GO:0003713 transcription coactivator activity 8/250 256/18639 0.03125 2.329875 0.0225409461200995 0.171281045222522 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/250 46/18639 0.0652173913043478 4.86234782608696 0.0236949809647572 0.171281045222522 GO:0031690 adrenergic receptor binding 2/250 18/18639 0.111111111111111 8.284 0.0238011545165732 0.171281045222522 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 5/250 122/18639 0.040983606557377 3.0555737704918 0.0243761722606833 0.171281045222522 GO:0005201 extracellular matrix structural constituent 6/250 168/18639 0.0357142857142857 2.66271428571429 0.0259783526927863 0.171281045222522 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/250 19/18639 0.105263157894737 7.848 0.0263694382913717 0.171281045222522 GO:0008301 DNA binding, bending 2/250 19/18639 0.105263157894737 7.848 0.0263694382913717 0.171281045222522 GO:0015245 fatty acid transmembrane transporter activity 2/250 19/18639 0.105263157894737 7.848 0.0263694382913717 0.171281045222522 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/250 19/18639 0.105263157894737 7.848 0.0263694382913717 0.171281045222522 GO:0097001 ceramide binding 2/250 19/18639 0.105263157894737 7.848 0.0263694382913717 0.171281045222522 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/250 48/18639 0.0625 4.65975 0.0264791311470436 0.171281045222522 GO:0005004 GPI-linked ephrin receptor activity 3/250 49/18639 0.0612244897959184 4.56465306122449 0.0279340092788951 0.171281045222522 GO:0005008 hepatocyte growth factor receptor activity 3/250 49/18639 0.0612244897959184 4.56465306122449 0.0279340092788951 0.171281045222522 GO:0005009 insulin receptor activity 3/250 49/18639 0.0612244897959184 4.56465306122449 0.0279340092788951 0.171281045222522 GO:0005011 macrophage colony-stimulating factor receptor activity 3/250 49/18639 0.0612244897959184 4.56465306122449 0.0279340092788951 0.171281045222522 GO:0005018 platelet-derived growth factor alpha-receptor activity 3/250 49/18639 0.0612244897959184 4.56465306122449 0.0279340092788951 0.171281045222522 GO:0005020 stem cell factor receptor activity 3/250 49/18639 0.0612244897959184 4.56465306122449 0.0279340092788951 0.171281045222522 GO:0008288 boss receptor activity 3/250 49/18639 0.0612244897959184 4.56465306122449 0.0279340092788951 0.171281045222522 GO:0036332 placental growth factor receptor activity 3/250 49/18639 0.0612244897959184 4.56465306122449 0.0279340092788951 0.171281045222522 GO:0038062 protein tyrosine kinase collagen receptor activity 3/250 49/18639 0.0612244897959184 4.56465306122449 0.0279340092788951 0.171281045222522 GO:0060175 brain-derived neurotrophic factor receptor activity 3/250 49/18639 0.0612244897959184 4.56465306122449 0.0279340092788951 0.171281045222522 GO:0016004 phospholipase activator activity 2/250 20/18639 0.1 7.4556 0.0290442971071652 0.171281045222522 GO:0016505 peptidase activator activity involved in apoptotic process 2/250 20/18639 0.1 7.4556 0.0290442971071652 0.171281045222522 GO:0042288 MHC class I protein binding 2/250 20/18639 0.1 7.4556 0.0290442971071652 0.171281045222522 GO:0008514 organic anion transmembrane transporter activity 8/250 269/18639 0.0297397769516729 2.21727881040892 0.0291251650002665 0.171281045222522 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 5/250 128/18639 0.0390625 2.91234375 0.0291958779951492 0.171281045222522 GO:0005007 fibroblast growth factor receptor activity 3/250 50/18639 0.06 4.47336 0.0294306439933436 0.171281045222522 GO:0005017 platelet-derived growth factor receptor activity 3/250 50/18639 0.06 4.47336 0.0294306439933436 0.171281045222522 GO:0005019 platelet-derived growth factor beta-receptor activity 3/250 50/18639 0.06 4.47336 0.0294306439933436 0.171281045222522 GO:0015605 organophosphate ester transmembrane transporter activity 3/250 50/18639 0.06 4.47336 0.0294306439933436 0.171281045222522 GO:0044389 ubiquitin-like protein ligase binding 9/250 322/18639 0.0279503105590062 2.08386335403727 0.0302076301016622 0.172464866857001 GO:0004197 cysteine-type endopeptidase activity 4/250 88/18639 0.0454545454545455 3.38890909090909 0.0306974901256306 0.172464866857001 GO:0005010 insulin-like growth factor receptor activity 3/250 51/18639 0.0588235294117647 4.38564705882353 0.0309689234603903 0.172464866857001 GO:0005021 vascular endothelial growth factor receptor activity 3/250 51/18639 0.0588235294117647 4.38564705882353 0.0309689234603903 0.172464866857001 GO:0005030 neurotrophin receptor activity 3/250 51/18639 0.0588235294117647 4.38564705882353 0.0309689234603903 0.172464866857001 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/250 21/18639 0.0952380952380952 7.10057142857143 0.0318224343978751 0.174214344245994 GO:0036122 BMP binding 2/250 21/18639 0.0952380952380952 7.10057142857143 0.0318224343978751 0.174214344245994 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/250 52/18639 0.0576923076923077 4.30130769230769 0.0325487146455748 0.176148220187568 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 5/250 132/18639 0.0378787878787879 2.82409090909091 0.0327210316137897 0.176148220187568 GO:0005003 ephrin receptor activity 3/250 53/18639 0.0566037735849057 4.22015094339623 0.0341698641129303 0.177909539389884 GO:0005005 transmembrane-ephrin receptor activity 3/250 53/18639 0.0566037735849057 4.22015094339623 0.0341698641129303 0.177909539389884 GO:0038064 collagen receptor activity 3/250 53/18639 0.0566037735849057 4.22015094339623 0.0341698641129303 0.177909539389884 GO:1901505 carbohydrate derivative transmembrane transporter activity 3/250 53/18639 0.0566037735849057 4.22015094339623 0.0341698641129303 0.177909539389884 GO:0031683 G-protein beta/gamma-subunit complex binding 2/250 22/18639 0.0909090909090909 6.77781818181818 0.0347006222339402 0.177909539389884 GO:0061133 endopeptidase activator activity 2/250 22/18639 0.0909090909090909 6.77781818181818 0.0347006222339402 0.177909539389884 GO:0098632 cell-cell adhesion mediator activity 3/250 55/18639 0.0545454545454545 4.06669090909091 0.0375355268181475 0.185790093555467 GO:0140313 molecular sequestering activity 3/250 55/18639 0.0545454545454545 4.06669090909091 0.0375355268181475 0.185790093555467 GO:0000295 adenine nucleotide transmembrane transporter activity 2/250 23/18639 0.0869565217391304 6.48313043478261 0.0376757000863253 0.185790093555467 GO:0004602 glutathione peroxidase activity 2/250 23/18639 0.0869565217391304 6.48313043478261 0.0376757000863253 0.185790093555467 GO:0017134 fibroblast growth factor binding 2/250 23/18639 0.0869565217391304 6.48313043478261 0.0376757000863253 0.185790093555467 GO:0015078 proton transmembrane transporter activity 6/250 185/18639 0.0324324324324324 2.41803243243243 0.038863215853205 0.189359673041646 GO:0004713 protein tyrosine kinase activity 5/250 140/18639 0.0357142857142857 2.66271428571429 0.0405391241421389 0.189359673041646 GO:0015149 hexose transmembrane transporter activity 2/250 24/18639 0.0833333333333333 6.213 0.0407445736111281 0.189359673041646 GO:0015295 solute:proton symporter activity 2/250 24/18639 0.0833333333333333 6.213 0.0407445736111281 0.189359673041646 GO:0035035 histone acetyltransferase binding 2/250 24/18639 0.0833333333333333 6.213 0.0407445736111281 0.189359673041646 GO:0055056 D-glucose transmembrane transporter activity 2/250 24/18639 0.0833333333333333 6.213 0.0407445736111281 0.189359673041646 GO:0060229 lipase activator activity 2/250 24/18639 0.0833333333333333 6.213 0.0407445736111281 0.189359673041646 GO:0070300 phosphatidic acid binding 2/250 24/18639 0.0833333333333333 6.213 0.0407445736111281 0.189359673041646 GO:0001848 complement binding 2/250 25/18639 0.08 5.96448 0.0439042134544551 0.202586584939843 GO:0022804 active transmembrane transporter activity 11/250 457/18639 0.0240700218818381 1.79456455142232 0.0449167915793372 0.205477469159223 GO:0005539 glycosaminoglycan binding 7/250 242/18639 0.0289256198347107 2.15657851239669 0.0451668740257116 0.205477469159223 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 9/250 349/18639 0.0257879656160458 1.92264756446991 0.0464210642279573 0.20862992146508 GO:0015145 monosaccharide transmembrane transporter activity 2/250 26/18639 0.0769230769230769 5.73507692307692 0.0471516540772472 0.20862992146508 GO:0015216 purine nucleotide transmembrane transporter activity 2/250 26/18639 0.0769230769230769 5.73507692307692 0.0471516540772472 0.20862992146508 GO:0030247 polysaccharide binding 2/250 26/18639 0.0769230769230769 5.73507692307692 0.0471516540772472 0.20862992146508 GO:0005044 scavenger receptor activity 2/250 27/18639 0.0740740740740741 5.52266666666667 0.0504839925997357 0.221854824621968 GO:0042277 peptide binding 7/250 249/18639 0.0281124497991968 2.09595180722892 0.0512041916599947 0.223303003922916 GO:0031625 ubiquitin protein ligase binding 8/250 302/18639 0.0264900662251656 1.97499337748344 0.051504872421849 0.223303003922916 GO:0016829 lyase activity 6/250 200/18639 0.03 2.23668 0.0531197272530116 0.227570970142038 GO:0046625 sphingolipid binding 2/250 28/18639 0.0714285714285714 5.32542857142857 0.0538983876652196 0.227570970142038 GO:0051119 sugar transmembrane transporter activity 2/250 28/18639 0.0714285714285714 5.32542857142857 0.0538983876652196 0.227570970142038 GO:0097718 disordered domain specific binding 2/250 28/18639 0.0714285714285714 5.32542857142857 0.0538983876652196 0.227570970142038 GO:0038024 cargo receptor activity 3/250 65/18639 0.0461538461538462 3.44104615384615 0.0567691681287431 0.238135601371221 GO:0004629 phospholipase C activity 2/250 29/18639 0.0689655172413793 5.14179310344828 0.0573920583228543 0.239195288235896 GO:0001968 fibronectin binding 2/250 30/18639 0.0666666666666667 4.9704 0.0609622829291512 0.248163314132947 GO:0015215 nucleotide transmembrane transporter activity 2/250 30/18639 0.0666666666666667 4.9704 0.0609622829291512 0.248163314132947 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/250 30/18639 0.0666666666666667 4.9704 0.0609622829291512 0.248163314132947 GO:0016500 protein-hormone receptor activity 3/250 67/18639 0.0447761194029851 3.33832835820896 0.061080444190617 0.248163314132947 GO:0008327 methyl-CpG binding 2/250 31/18639 0.0645161290322581 4.81006451612903 0.0646063980678891 0.25922815622271 GO:0072349 modified amino acid transmembrane transporter activity 2/250 31/18639 0.0645161290322581 4.81006451612903 0.0646063980678891 0.25922815622271 GO:0008083 growth factor activity 5/250 162/18639 0.0308641975308642 2.30111111111111 0.0674457247665972 0.268950235797665 GO:0035401 histone H3Y41 kinase activity 4/250 115/18639 0.0347826086956522 2.59325217391304 0.0692034458005206 0.272594060897173 GO:0140801 histone H2AXY142 kinase activity 4/250 115/18639 0.0347826086956522 2.59325217391304 0.0692034458005206 0.272594060897173 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 7/250 268/18639 0.0261194029850746 1.94735820895522 0.0700630549166638 0.27430747561312 GO:0015103 inorganic anion transmembrane transporter activity 5/250 165/18639 0.0303030303030303 2.25927272727273 0.0717316713860948 0.279148552502513 GO:0019825 oxygen binding 2/250 34/18639 0.0588235294117647 4.38564705882353 0.0759563037487328 0.292070072748104 GO:0090482 vitamin transmembrane transporter activity 2/250 34/18639 0.0588235294117647 4.38564705882353 0.0759563037487328 0.292070072748104 GO:0048029 monosaccharide binding 3/250 74/18639 0.0405405405405405 3.02254054054054 0.0773174833453866 0.295544936337987 GO:0005343 organic acid:sodium symporter activity 2/250 35/18639 0.0571428571428571 4.26034285714286 0.0798704746039137 0.303507803494872 GO:0001217 DNA-binding transcription repressor activity 7/250 278/18639 0.0251798561151079 1.87730935251799 0.0814573032909852 0.307727590210389 GO:0098631 cell adhesion mediator activity 3/250 76/18639 0.0394736842105263 2.943 0.0822709110929517 0.307753136514488 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/250 36/18639 0.0555555555555556 4.142 0.0838460557686531 0.307753136514488 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/250 36/18639 0.0555555555555556 4.142 0.0838460557686531 0.307753136514488 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/250 36/18639 0.0555555555555556 4.142 0.0838460557686531 0.307753136514488 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/250 36/18639 0.0555555555555556 4.142 0.0838460557686531 0.307753136514488 GO:0042805 actinin binding 2/250 37/18639 0.0540540540540541 4.03005405405405 0.0878807115031913 0.320739771926901 GO:0005319 lipid transporter activity 5/250 178/18639 0.0280898876404494 2.09426966292135 0.0919789843044291 0.328974573698855 GO:0031490 chromatin DNA binding 4/250 128/18639 0.03125 2.329875 0.0937305265794409 0.328974573698855 GO:0033192 calmodulin-dependent protein phosphatase activity 3/250 81/18639 0.037037037037037 2.76133333333333 0.095229481860195 0.328974573698855 GO:0140791 histone H2AXS140 phosphatase activity 3/250 81/18639 0.037037037037037 2.76133333333333 0.095229481860195 0.328974573698855 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 3/250 81/18639 0.037037037037037 2.76133333333333 0.095229481860195 0.328974573698855 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 3/250 81/18639 0.037037037037037 2.76133333333333 0.095229481860195 0.328974573698855 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 3/250 81/18639 0.037037037037037 2.76133333333333 0.095229481860195 0.328974573698855 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 3/250 81/18639 0.037037037037037 2.76133333333333 0.095229481860195 0.328974573698855 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 3/250 81/18639 0.037037037037037 2.76133333333333 0.095229481860195 0.328974573698855 GO:1990439 MAP kinase serine/threonine phosphatase activity 3/250 81/18639 0.037037037037037 2.76133333333333 0.095229481860195 0.328974573698855 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/250 39/18639 0.0512820512820513 3.82338461538462 0.0961181585702742 0.330278353385091 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 3/250 82/18639 0.0365853658536585 2.72765853658537 0.0979160536530605 0.332914582420406 GO:0033549 MAP kinase phosphatase activity 3/250 82/18639 0.0365853658536585 2.72765853658537 0.0979160536530605 0.332914582420406 GO:0015144 carbohydrate transmembrane transporter activity 2/250 40/18639 0.05 3.7278 0.100316530457952 0.333379519112115 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/250 40/18639 0.05 3.7278 0.100316530457952 0.333379519112115 GO:0071855 neuropeptide receptor binding 2/250 40/18639 0.05 3.7278 0.100316530457952 0.333379519112115 GO:0140662 ATP-dependent protein folding chaperone 2/250 40/18639 0.05 3.7278 0.100316530457952 0.333379519112115 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 3/250 83/18639 0.036144578313253 2.69479518072289 0.10063313657409 0.333379519112115 GO:0008237 metallopeptidase activity 5/250 184/18639 0.0271739130434783 2.02597826086957 0.102218390678049 0.336903471316427 GO:0004860 protein kinase inhibitor activity 3/250 84/18639 0.0357142857142857 2.66271428571429 0.103380247694313 0.337291111164273 GO:0017018 myosin phosphatase activity 3/250 84/18639 0.0357142857142857 2.66271428571429 0.103380247694313 0.337291111164273 GO:0042169 SH2 domain binding 2/250 41/18639 0.0487804878048781 3.63687804878049 0.104565136187281 0.337745389884917 GO:0042287 MHC protein binding 2/250 41/18639 0.0487804878048781 3.63687804878049 0.104565136187281 0.337745389884917 GO:0008307 structural constituent of muscle 2/250 42/18639 0.0476190476190476 3.55028571428571 0.108861886537399 0.347973076507642 GO:0035198 miRNA binding 2/250 42/18639 0.0476190476190476 3.55028571428571 0.108861886537399 0.347973076507642 GO:0046943 carboxylic acid transmembrane transporter activity 5/250 188/18639 0.0265957446808511 1.98287234042553 0.109347576673454 0.347973076507642 GO:0019838 growth factor binding 4/250 136/18639 0.0294117647058824 2.19282352941176 0.110604210013393 0.34853814472513 GO:0044325 transmembrane transporter binding 4/250 136/18639 0.0294117647058824 2.19282352941176 0.110604210013393 0.34853814472513 GO:0005342 organic acid transmembrane transporter activity 5/250 189/18639 0.0264550264550265 1.97238095238095 0.111166964414577 0.348610966076779 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/250 89/18639 0.0337078651685393 2.51312359550562 0.117549102522943 0.363465243266169 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/250 89/18639 0.0337078651685393 2.51312359550562 0.117549102522943 0.363465243266169 GO:0001046 core promoter sequence-specific DNA binding 2/250 44/18639 0.0454545454545455 3.38890909090909 0.117591696350819 0.363465243266169 GO:0019210 kinase inhibitor activity 3/250 90/18639 0.0333333333333333 2.4852 0.12046607206093 0.367128626056951 GO:0140793 histone H2AXY142 phosphatase activity 3/250 90/18639 0.0333333333333333 2.4852 0.12046607206093 0.367128626056951 GO:0008236 serine-type peptidase activity 5/250 194/18639 0.0257731958762887 1.92154639175258 0.120481840130145 0.367128626056951 GO:0042605 peptide antigen binding 2/250 45/18639 0.0444444444444444 3.3136 0.122020806923837 0.368074977799168 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/250 10/18639 0.1 7.4556 0.126343353644063 0.368074977799168 GO:0005345 purine nucleobase transmembrane transporter activity 1/250 10/18639 0.1 7.4556 0.126343353644063 0.368074977799168 GO:0005381 iron ion transmembrane transporter activity 1/250 10/18639 0.1 7.4556 0.126343353644063 0.368074977799168 GO:0008239 dipeptidyl-peptidase activity 1/250 10/18639 0.1 7.4556 0.126343353644063 0.368074977799168 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/250 10/18639 0.1 7.4556 0.126343353644063 0.368074977799168 GO:0042975 peroxisome proliferator activated receptor binding 1/250 10/18639 0.1 7.4556 0.126343353644063 0.368074977799168 GO:0043208 glycosphingolipid binding 1/250 10/18639 0.1 7.4556 0.126343353644063 0.368074977799168 GO:0070513 death domain binding 1/250 10/18639 0.1 7.4556 0.126343353644063 0.368074977799168 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/250 46/18639 0.0434782608695652 3.2415652173913 0.12649016264925 0.368074977799168 GO:0017171 serine hydrolase activity 5/250 198/18639 0.0252525252525253 1.88272727272727 0.128189348815691 0.371346723475052 GO:0019887 protein kinase regulator activity 6/250 255/18639 0.0235294117647059 1.75425882352941 0.129260424384681 0.372777831037965 GO:0042562 hormone binding 3/250 94/18639 0.0319148936170213 2.37944680851064 0.132394620458239 0.377931270094479 GO:0038187 pattern recognition receptor activity 2/250 48/18639 0.0416666666666667 3.1065 0.135542193039188 0.377931270094479 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/250 11/18639 0.0909090909090909 6.77781818181818 0.138067770498912 0.377931270094479 GO:0005114 type II transforming growth factor beta receptor binding 1/250 11/18639 0.0909090909090909 6.77781818181818 0.138067770498912 0.377931270094479 GO:0008271 secondary active sulfate transmembrane transporter activity 1/250 11/18639 0.0909090909090909 6.77781818181818 0.138067770498912 0.377931270094479 GO:0008526 phosphatidylinositol transfer activity 1/250 11/18639 0.0909090909090909 6.77781818181818 0.138067770498912 0.377931270094479 GO:0010854 adenylate cyclase regulator activity 1/250 11/18639 0.0909090909090909 6.77781818181818 0.138067770498912 0.377931270094479 GO:0015205 nucleobase transmembrane transporter activity 1/250 11/18639 0.0909090909090909 6.77781818181818 0.138067770498912 0.377931270094479 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/250 11/18639 0.0909090909090909 6.77781818181818 0.138067770498912 0.377931270094479 GO:0034713 type I transforming growth factor beta receptor binding 1/250 11/18639 0.0909090909090909 6.77781818181818 0.138067770498912 0.377931270094479 GO:0045294 alpha-catenin binding 1/250 11/18639 0.0909090909090909 6.77781818181818 0.138067770498912 0.377931270094479 GO:0070697 activin receptor binding 1/250 11/18639 0.0909090909090909 6.77781818181818 0.138067770498912 0.377931270094479 GO:0001222 transcription corepressor binding 2/250 49/18639 0.0408163265306122 3.04310204081633 0.140121264688562 0.378844732804458 GO:0016763 pentosyltransferase activity 2/250 49/18639 0.0408163265306122 3.04310204081633 0.140121264688562 0.378844732804458 GO:0003714 transcription corepressor activity 5/250 204/18639 0.0245098039215686 1.82735294117647 0.140160822198553 0.378844732804458 GO:0004725 protein tyrosine phosphatase activity 3/250 98/18639 0.0306122448979592 2.28232653061224 0.144716063241214 0.380568944579223 GO:0003995 acyl-CoA dehydrogenase activity 1/250 12/18639 0.0833333333333333 6.213 0.149635467373255 0.380568944579223 GO:0004032 aldose reductase (NADPH) activity 1/250 12/18639 0.0833333333333333 6.213 0.149635467373255 0.380568944579223 GO:0004300 enoyl-CoA hydratase activity 1/250 12/18639 0.0833333333333333 6.213 0.149635467373255 0.380568944579223 GO:0005049 nuclear export signal receptor activity 1/250 12/18639 0.0833333333333333 6.213 0.149635467373255 0.380568944579223 GO:0010853 cyclase activator activity 1/250 12/18639 0.0833333333333333 6.213 0.149635467373255 0.380568944579223 GO:0015132 prostaglandin transmembrane transporter activity 1/250 12/18639 0.0833333333333333 6.213 0.149635467373255 0.380568944579223 GO:0016208 AMP binding 1/250 12/18639 0.0833333333333333 6.213 0.149635467373255 0.380568944579223 GO:0042301 phosphate ion binding 1/250 12/18639 0.0833333333333333 6.213 0.149635467373255 0.380568944579223 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/250 12/18639 0.0833333333333333 6.213 0.149635467373255 0.380568944579223 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/250 12/18639 0.0833333333333333 6.213 0.149635467373255 0.380568944579223 GO:0070008 serine-type exopeptidase activity 1/250 12/18639 0.0833333333333333 6.213 0.149635467373255 0.380568944579223 GO:0070679 inositol 1,4,5 trisphosphate binding 1/250 12/18639 0.0833333333333333 6.213 0.149635467373255 0.380568944579223 GO:0097677 STAT family protein binding 1/250 12/18639 0.0833333333333333 6.213 0.149635467373255 0.380568944579223 GO:1990817 poly(A) RNA polymerase activity 1/250 12/18639 0.0833333333333333 6.213 0.149635467373255 0.380568944579223 GO:0005080 protein kinase C binding 2/250 52/18639 0.0384615384615385 2.86753846153846 0.154049945088057 0.388199070601901 GO:0008238 exopeptidase activity 3/250 102/18639 0.0294117647058824 2.19282352941176 0.157398105555318 0.388199070601901 GO:0003924 GTPase activity 7/250 331/18639 0.0211480362537764 1.57671299093656 0.158185126247369 0.388199070601901 GO:0016860 intramolecular oxidoreductase activity 2/250 53/18639 0.0377358490566038 2.81343396226415 0.158751124734141 0.388199070601901 GO:0017046 peptide hormone binding 2/250 53/18639 0.0377358490566038 2.81343396226415 0.158751124734141 0.388199070601901 GO:0004722 protein serine/threonine phosphatase activity 3/250 103/18639 0.029126213592233 2.17153398058252 0.160621183068342 0.388199070601901 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/250 13/18639 0.0769230769230769 5.73507692307692 0.16104853083794 0.388199070601901 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/250 13/18639 0.0769230769230769 5.73507692307692 0.16104853083794 0.388199070601901 GO:0030955 potassium ion binding 1/250 13/18639 0.0769230769230769 5.73507692307692 0.16104853083794 0.388199070601901 GO:0035673 oligopeptide transmembrane transporter activity 1/250 13/18639 0.0769230769230769 5.73507692307692 0.16104853083794 0.388199070601901 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/250 13/18639 0.0769230769230769 5.73507692307692 0.16104853083794 0.388199070601901 GO:0071714 icosanoid transmembrane transporter activity 1/250 13/18639 0.0769230769230769 5.73507692307692 0.16104853083794 0.388199070601901 GO:0140333 glycerophospholipid flippase activity 1/250 13/18639 0.0769230769230769 5.73507692307692 0.16104853083794 0.388199070601901 GO:0140666 annealing activity 1/250 13/18639 0.0769230769230769 5.73507692307692 0.16104853083794 0.388199070601901 GO:0003925 G protein activity 2/250 54/18639 0.037037037037037 2.76133333333333 0.163478775731318 0.389694793809709 GO:0051287 NAD binding 2/250 54/18639 0.037037037037037 2.76133333333333 0.163478775731318 0.389694793809709 GO:0140463 chromatin-protein adaptor activity 2/250 54/18639 0.037037037037037 2.76133333333333 0.163478775731318 0.389694793809709 GO:1901681 sulfur compound binding 6/250 275/18639 0.0218181818181818 1.62667636363636 0.165597322863544 0.393293641800917 GO:0004497 monooxygenase activity 3/250 106/18639 0.0283018867924528 2.11007547169811 0.17040856425183 0.398966404253579 GO:0005178 integrin binding 4/250 161/18639 0.0248447204968944 1.85232298136646 0.170906169542595 0.398966404253579 GO:0008392 arachidonate epoxygenase activity 1/250 14/18639 0.0714285714285714 5.32542857142857 0.172309019793728 0.398966404253579 GO:0008494 translation activator activity 1/250 14/18639 0.0714285714285714 5.32542857142857 0.172309019793728 0.398966404253579 GO:0019992 diacylglycerol binding 1/250 14/18639 0.0714285714285714 5.32542857142857 0.172309019793728 0.398966404253579 GO:0031404 chloride ion binding 1/250 14/18639 0.0714285714285714 5.32542857142857 0.172309019793728 0.398966404253579 GO:0032036 myosin heavy chain binding 1/250 14/18639 0.0714285714285714 5.32542857142857 0.172309019793728 0.398966404253579 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/250 57/18639 0.0350877192982456 2.616 0.17780526908789 0.405783054556681 GO:0015081 sodium ion transmembrane transporter activity 4/250 164/18639 0.024390243902439 1.81843902439024 0.178805358841823 0.405783054556681 GO:0004620 phospholipase activity 3/250 109/18639 0.0275229357798165 2.052 0.180362736706636 0.405783054556681 GO:0061980 regulatory RNA binding 2/250 58/18639 0.0344827586206897 2.57089655172414 0.182623697117494 0.405783054556681 GO:0015116 sulfate transmembrane transporter activity 1/250 15/18639 0.0666666666666667 4.9704 0.183418965836766 0.405783054556681 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/250 15/18639 0.0666666666666667 4.9704 0.183418965836766 0.405783054556681 GO:0015929 hexosaminidase activity 1/250 15/18639 0.0666666666666667 4.9704 0.183418965836766 0.405783054556681 GO:0016846 carbon-sulfur lyase activity 1/250 15/18639 0.0666666666666667 4.9704 0.183418965836766 0.405783054556681 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/250 15/18639 0.0666666666666667 4.9704 0.183418965836766 0.405783054556681 GO:0017081 chloride channel regulator activity 1/250 15/18639 0.0666666666666667 4.9704 0.183418965836766 0.405783054556681 GO:0031005 filamin binding 1/250 15/18639 0.0666666666666667 4.9704 0.183418965836766 0.405783054556681 GO:0051371 muscle alpha-actinin binding 1/250 15/18639 0.0666666666666667 4.9704 0.183418965836766 0.405783054556681 GO:0140161 monocarboxylate:sodium symporter activity 1/250 15/18639 0.0666666666666667 4.9704 0.183418965836766 0.405783054556681 GO:0001786 phosphatidylserine binding 2/250 59/18639 0.0338983050847458 2.5273220338983 0.187461219300473 0.411704004452555 GO:0019207 kinase regulator activity 6/250 287/18639 0.0209059233449477 1.55866202090592 0.189268962953439 0.411704004452555 GO:0043022 ribosome binding 3/250 112/18639 0.0267857142857143 1.99703571428571 0.190470415604089 0.411704004452555 GO:0000062 fatty-acyl-CoA binding 1/250 16/18639 0.0625 4.65975 0.194380373619241 0.411704004452555 GO:0003688 DNA replication origin binding 1/250 16/18639 0.0625 4.65975 0.194380373619241 0.411704004452555 GO:0005159 insulin-like growth factor receptor binding 1/250 16/18639 0.0625 4.65975 0.194380373619241 0.411704004452555 GO:0008391 arachidonate monooxygenase activity 1/250 16/18639 0.0625 4.65975 0.194380373619241 0.411704004452555 GO:0015378 sodium:chloride symporter activity 1/250 16/18639 0.0625 4.65975 0.194380373619241 0.411704004452555 GO:0016722 oxidoreductase activity, acting on metal ions 1/250 16/18639 0.0625 4.65975 0.194380373619241 0.411704004452555 GO:0019841 retinol binding 1/250 16/18639 0.0625 4.65975 0.194380373619241 0.411704004452555 GO:0055102 lipase inhibitor activity 1/250 16/18639 0.0625 4.65975 0.194380373619241 0.411704004452555 GO:0070411 I-SMAD binding 1/250 16/18639 0.0625 4.65975 0.194380373619241 0.411704004452555 GO:0140327 flippase activity 1/250 16/18639 0.0625 4.65975 0.194380373619241 0.411704004452555 GO:0016836 hydro-lyase activity 2/250 61/18639 0.0327868852459016 2.44445901639344 0.197188092826978 0.416285973745842 GO:0008201 heparin binding 4/250 172/18639 0.0232558139534884 1.73386046511628 0.200442972871446 0.421779024348385 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/250 17/18639 0.0588235294117647 4.38564705882353 0.2051952212053 0.423501958142568 GO:0005092 GDP-dissociation inhibitor activity 1/250 17/18639 0.0588235294117647 4.38564705882353 0.2051952212053 0.423501958142568 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/250 17/18639 0.0588235294117647 4.38564705882353 0.2051952212053 0.423501958142568 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/250 17/18639 0.0588235294117647 4.38564705882353 0.2051952212053 0.423501958142568 GO:0046965 nuclear retinoid X receptor binding 1/250 17/18639 0.0588235294117647 4.38564705882353 0.2051952212053 0.423501958142568 GO:1901567 fatty acid derivative binding 1/250 17/18639 0.0588235294117647 4.38564705882353 0.2051952212053 0.423501958142568 GO:1901682 sulfur compound transmembrane transporter activity 2/250 63/18639 0.0317460317460317 2.36685714285714 0.206975310084115 0.42581544686095 GO:0001664 G protein-coupled receptor binding 6/250 297/18639 0.0202020202020202 1.50618181818182 0.209935091247516 0.428321312781471 GO:0004252 serine-type endopeptidase activity 4/250 176/18639 0.0227272727272727 1.69445454545455 0.211545933179329 0.428321312781471 GO:0043021 ribonucleoprotein complex binding 4/250 177/18639 0.0225988700564972 1.6848813559322 0.214348696283926 0.428321312781471 GO:0003746 translation elongation factor activity 1/250 18/18639 0.0555555555555556 4.142 0.215865460422284 0.428321312781471 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/250 18/18639 0.0555555555555556 4.142 0.215865460422284 0.428321312781471 GO:0008525 phosphatidylcholine transporter activity 1/250 18/18639 0.0555555555555556 4.142 0.215865460422284 0.428321312781471 GO:0015373 monoatomic anion:sodium symporter activity 1/250 18/18639 0.0555555555555556 4.142 0.215865460422284 0.428321312781471 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/250 18/18639 0.0555555555555556 4.142 0.215865460422284 0.428321312781471 GO:0034185 apolipoprotein binding 1/250 18/18639 0.0555555555555556 4.142 0.215865460422284 0.428321312781471 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/250 18/18639 0.0555555555555556 4.142 0.215865460422284 0.428321312781471 GO:0050811 GABA receptor binding 1/250 18/18639 0.0555555555555556 4.142 0.215865460422284 0.428321312781471 GO:0042578 phosphoric ester hydrolase activity 7/250 363/18639 0.0192837465564738 1.43771900826446 0.21618976536905 0.428321312781471 GO:0019843 rRNA binding 2/250 65/18639 0.0307692307692308 2.29403076923077 0.216812800742323 0.428321312781471 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/250 181/18639 0.0220994475138122 1.64764640883978 0.225660713061659 0.437141420433149 GO:0016918 retinal binding 1/250 19/18639 0.0526315789473684 3.924 0.226393017207335 0.437141420433149 GO:0031420 alkali metal ion binding 1/250 19/18639 0.0526315789473684 3.924 0.226393017207335 0.437141420433149 GO:0042577 lipid phosphatase activity 1/250 19/18639 0.0526315789473684 3.924 0.226393017207335 0.437141420433149 GO:0046624 sphingolipid transporter activity 1/250 19/18639 0.0526315789473684 3.924 0.226393017207335 0.437141420433149 GO:0050145 nucleoside monophosphate kinase activity 1/250 19/18639 0.0526315789473684 3.924 0.226393017207335 0.437141420433149 GO:0120227 acyl-CoA binding 1/250 19/18639 0.0526315789473684 3.924 0.226393017207335 0.437141420433149 GO:0050840 extracellular matrix binding 2/250 67/18639 0.0298507462686567 2.22555223880597 0.226690984280348 0.437141420433149 GO:0005548 phospholipid transporter activity 2/250 68/18639 0.0294117647058824 2.19282352941176 0.231642471264019 0.445360227489751 GO:0000339 RNA cap binding 1/250 20/18639 0.05 3.7278 0.236779791949449 0.451208689083611 GO:0010851 cyclase regulator activity 1/250 20/18639 0.05 3.7278 0.236779791949449 0.451208689083611 GO:0043024 ribosomal small subunit binding 1/250 20/18639 0.05 3.7278 0.236779791949449 0.451208689083611 GO:0008234 cysteine-type peptidase activity 4/250 187/18639 0.0213903743315508 1.5947807486631 0.242905617473195 0.459039770755507 GO:0031406 carboxylic acid binding 4/250 187/18639 0.0213903743315508 1.5947807486631 0.242905617473195 0.459039770755507 GO:0140104 molecular carrier activity 5/250 249/18639 0.0200803212851406 1.49710843373494 0.243021055105857 0.459039770755507 GO:0005525 GTP binding 7/250 378/18639 0.0185185185185185 1.38066666666667 0.245737274725156 0.459884346536772 GO:0001846 opsonin binding 1/250 21/18639 0.0476190476190476 3.55028571428571 0.247027659827028 0.459884346536772 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/250 21/18639 0.0476190476190476 3.55028571428571 0.247027659827028 0.459884346536772 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/250 21/18639 0.0476190476190476 3.55028571428571 0.247027659827028 0.459884346536772 GO:0072542 protein phosphatase activator activity 1/250 21/18639 0.0476190476190476 3.55028571428571 0.247027659827028 0.459884346536772 GO:0043177 organic acid binding 4/250 189/18639 0.0211640211640212 1.57790476190476 0.24872023343958 0.461704801155082 GO:0005518 collagen binding 2/250 72/18639 0.0277777777777778 2.071 0.251505803682931 0.464453561408571 GO:0019902 phosphatase binding 4/250 190/18639 0.0210526315789474 1.5696 0.251638926459752 0.464453561408571 GO:0016298 lipase activity 3/250 130/18639 0.0230769230769231 1.72052307692308 0.253622596929006 0.466781189789567 GO:0008970 phospholipase A1 activity 1/250 22/18639 0.0454545454545455 3.38890909090909 0.257138471140984 0.467919584104439 GO:0015377 chloride:monoatomic cation symporter activity 1/250 22/18639 0.0454545454545455 3.38890909090909 0.257138471140984 0.467919584104439 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/250 22/18639 0.0454545454545455 3.38890909090909 0.257138471140984 0.467919584104439 GO:0033691 sialic acid binding 1/250 22/18639 0.0454545454545455 3.38890909090909 0.257138471140984 0.467919584104439 GO:0005283 amino acid:sodium symporter activity 1/250 23/18639 0.0434782608695652 3.2415652173913 0.267114051643469 0.477993566098839 GO:0008171 O-methyltransferase activity 1/250 23/18639 0.0434782608695652 3.2415652173913 0.267114051643469 0.477993566098839 GO:0042171 lysophosphatidic acid acyltransferase activity 1/250 23/18639 0.0434782608695652 3.2415652173913 0.267114051643469 0.477993566098839 GO:0043274 phospholipase binding 1/250 23/18639 0.0434782608695652 3.2415652173913 0.267114051643469 0.477993566098839 GO:0070577 lysine-acetylated histone binding 1/250 23/18639 0.0434782608695652 3.2415652173913 0.267114051643469 0.477993566098839 GO:0071617 lysophospholipid acyltransferase activity 1/250 23/18639 0.0434782608695652 3.2415652173913 0.267114051643469 0.477993566098839 GO:0015297 antiporter activity 3/250 135/18639 0.0222222222222222 1.6568 0.271702480529472 0.482247188811386 GO:0140789 histone phosphatase activity 3/250 136/18639 0.0220588235294118 1.64461764705882 0.275336276105023 0.482247188811386 GO:0005315 phosphate transmembrane transporter activity 1/250 24/18639 0.0416666666666667 3.1065 0.276956202862266 0.482247188811386 GO:0005540 hyaluronic acid binding 1/250 24/18639 0.0416666666666667 3.1065 0.276956202862266 0.482247188811386 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/250 24/18639 0.0416666666666667 3.1065 0.276956202862266 0.482247188811386 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/250 24/18639 0.0416666666666667 3.1065 0.276956202862266 0.482247188811386 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/250 24/18639 0.0416666666666667 3.1065 0.276956202862266 0.482247188811386 GO:0050431 transforming growth factor beta binding 1/250 24/18639 0.0416666666666667 3.1065 0.276956202862266 0.482247188811386 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/250 24/18639 0.0416666666666667 3.1065 0.276956202862266 0.482247188811386 GO:0140033 acetylation-dependent protein binding 1/250 24/18639 0.0416666666666667 3.1065 0.276956202862266 0.482247188811386 GO:0016922 nuclear receptor binding 3/250 137/18639 0.0218978102189781 1.63261313868613 0.278975075216949 0.484456716640185 GO:0033293 monocarboxylic acid binding 2/250 79/18639 0.0253164556962025 1.88749367088608 0.286335244033091 0.484781910376747 GO:0046332 SMAD binding 2/250 79/18639 0.0253164556962025 1.88749367088608 0.286335244033091 0.484781910376747 GO:0005537 D-mannose binding 1/250 25/18639 0.04 2.98224 0.286666702420925 0.484781910376747 GO:0008139 nuclear localization sequence binding 1/250 25/18639 0.04 2.98224 0.286666702420925 0.484781910376747 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/250 25/18639 0.04 2.98224 0.286666702420925 0.484781910376747 GO:0015645 fatty acid ligase activity 1/250 25/18639 0.04 2.98224 0.286666702420925 0.484781910376747 GO:0019211 phosphatase activator activity 1/250 25/18639 0.04 2.98224 0.286666702420925 0.484781910376747 GO:0042974 nuclear retinoic acid receptor binding 1/250 25/18639 0.04 2.98224 0.286666702420925 0.484781910376747 GO:0120020 cholesterol transfer activity 1/250 25/18639 0.04 2.98224 0.286666702420925 0.484781910376747 GO:0120515 fatty acid-CoA ligase activity 1/250 25/18639 0.04 2.98224 0.286666702420925 0.484781910376747 GO:0019001 guanyl nucleotide binding 7/250 400/18639 0.0175 1.30473 0.291133691269342 0.489452068064241 GO:0032561 guanyl ribonucleotide binding 7/250 400/18639 0.0175 1.30473 0.291133691269342 0.489452068064241 GO:0004435 phosphatidylinositol phospholipase C activity 1/250 26/18639 0.0384615384615385 2.86753846153846 0.296247304354672 0.489452068064241 GO:0005160 transforming growth factor beta receptor binding 1/250 26/18639 0.0384615384615385 2.86753846153846 0.296247304354672 0.489452068064241 GO:0008143 poly(A) binding 1/250 26/18639 0.0384615384615385 2.86753846153846 0.296247304354672 0.489452068064241 GO:0050681 nuclear androgen receptor binding 1/250 26/18639 0.0384615384615385 2.86753846153846 0.296247304354672 0.489452068064241 GO:0070412 R-SMAD binding 1/250 26/18639 0.0384615384615385 2.86753846153846 0.296247304354672 0.489452068064241 GO:0097602 cullin family protein binding 1/250 26/18639 0.0384615384615385 2.86753846153846 0.296247304354672 0.489452068064241 GO:0120014 phospholipid transfer activity 1/250 26/18639 0.0384615384615385 2.86753846153846 0.296247304354672 0.489452068064241 GO:0016791 phosphatase activity 5/250 273/18639 0.0183150183150183 1.36549450549451 0.304441699915475 0.492473894430727 GO:0019903 protein phosphatase binding 3/250 144/18639 0.0208333333333333 1.55325 0.304554324706193 0.492473894430727 GO:0001671 ATPase activator activity 1/250 27/18639 0.037037037037037 2.76133333333333 0.30569973942217 0.492473894430727 GO:0004364 glutathione transferase activity 1/250 27/18639 0.037037037037037 2.76133333333333 0.30569973942217 0.492473894430727 GO:0008266 poly(U) RNA binding 1/250 27/18639 0.037037037037037 2.76133333333333 0.30569973942217 0.492473894430727 GO:0008395 steroid hydroxylase activity 1/250 27/18639 0.037037037037037 2.76133333333333 0.30569973942217 0.492473894430727 GO:0015252 proton channel activity 1/250 27/18639 0.037037037037037 2.76133333333333 0.30569973942217 0.492473894430727 GO:0016405 CoA-ligase activity 1/250 27/18639 0.037037037037037 2.76133333333333 0.30569973942217 0.492473894430727 GO:0035255 ionotropic glutamate receptor binding 1/250 27/18639 0.037037037037037 2.76133333333333 0.30569973942217 0.492473894430727 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/250 27/18639 0.037037037037037 2.76133333333333 0.30569973942217 0.492473894430727 GO:0016866 intramolecular transferase activity 1/250 28/18639 0.0357142857142857 2.66271428571429 0.315025715413168 0.503729238012145 GO:0051019 mitogen-activated protein kinase binding 1/250 28/18639 0.0357142857142857 2.66271428571429 0.315025715413168 0.503729238012145 GO:0051393 alpha-actinin binding 1/250 28/18639 0.0357142857142857 2.66271428571429 0.315025715413168 0.503729238012145 GO:0050660 flavin adenine dinucleotide binding 2/250 86/18639 0.0232558139534884 1.73386046511628 0.320995387621106 0.509612137893094 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/250 29/18639 0.0344827586206897 2.57089655172414 0.324226917452108 0.509612137893094 GO:0005416 amino acid:monoatomic cation symporter activity 1/250 29/18639 0.0344827586206897 2.57089655172414 0.324226917452108 0.509612137893094 GO:0043236 laminin binding 1/250 29/18639 0.0344827586206897 2.57089655172414 0.324226917452108 0.509612137893094 GO:0051861 glycolipid binding 1/250 29/18639 0.0344827586206897 2.57089655172414 0.324226917452108 0.509612137893094 GO:0097472 cyclin-dependent protein kinase activity 1/250 29/18639 0.0344827586206897 2.57089655172414 0.324226917452108 0.509612137893094 GO:0106222 lncRNA binding 1/250 29/18639 0.0344827586206897 2.57089655172414 0.324226917452108 0.509612137893094 GO:0008081 phosphoric diester hydrolase activity 2/250 87/18639 0.0229885057471264 1.71393103448276 0.325917705643202 0.511026305450264 GO:0001965 G-protein alpha-subunit binding 1/250 30/18639 0.0333333333333333 2.4852 0.333305008297727 0.511437138623115 GO:0008187 poly-pyrimidine tract binding 1/250 30/18639 0.0333333333333333 2.4852 0.333305008297727 0.511437138623115 GO:0016769 transferase activity, transferring nitrogenous groups 1/250 30/18639 0.0333333333333333 2.4852 0.333305008297727 0.511437138623115 GO:0031210 phosphatidylcholine binding 1/250 30/18639 0.0333333333333333 2.4852 0.333305008297727 0.511437138623115 GO:0031624 ubiquitin conjugating enzyme binding 1/250 30/18639 0.0333333333333333 2.4852 0.333305008297727 0.511437138623115 GO:0033612 receptor serine/threonine kinase binding 1/250 30/18639 0.0333333333333333 2.4852 0.333305008297727 0.511437138623115 GO:0048019 receptor antagonist activity 1/250 30/18639 0.0333333333333333 2.4852 0.333305008297727 0.511437138623115 GO:0051721 protein phosphatase 2A binding 1/250 30/18639 0.0333333333333333 2.4852 0.333305008297727 0.511437138623115 GO:0070566 adenylyltransferase activity 1/250 30/18639 0.0333333333333333 2.4852 0.333305008297727 0.511437138623115 GO:0003727 single-stranded RNA binding 2/250 89/18639 0.0224719101123595 1.67541573033708 0.335733719174815 0.513943086698888 GO:0005506 iron ion binding 3/250 154/18639 0.0194805194805195 1.45238961038961 0.341236546653977 0.514188400233986 GO:0005184 neuropeptide hormone activity 1/250 31/18639 0.032258064516129 2.40503225806452 0.342261628638722 0.514188400233986 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/250 31/18639 0.032258064516129 2.40503225806452 0.342261628638722 0.514188400233986 GO:0005452 solute:inorganic anion antiporter activity 1/250 31/18639 0.032258064516129 2.40503225806452 0.342261628638722 0.514188400233986 GO:0016411 acylglycerol O-acyltransferase activity 1/250 31/18639 0.032258064516129 2.40503225806452 0.342261628638722 0.514188400233986 GO:0016878 acid-thiol ligase activity 1/250 31/18639 0.032258064516129 2.40503225806452 0.342261628638722 0.514188400233986 GO:0047499 calcium-independent phospholipase A2 activity 1/250 31/18639 0.032258064516129 2.40503225806452 0.342261628638722 0.514188400233986 GO:0070273 phosphatidylinositol-4-phosphate binding 1/250 31/18639 0.032258064516129 2.40503225806452 0.342261628638722 0.514188400233986 GO:0072341 modified amino acid binding 2/250 91/18639 0.021978021978022 1.63859340659341 0.345507436592945 0.514307402972884 GO:0140375 immune receptor activity 3/250 156/18639 0.0192307692307692 1.43376923076923 0.348566727397498 0.514307402972884 GO:0043178 alcohol binding 2/250 92/18639 0.0217391304347826 1.62078260869565 0.350376952574185 0.514307402972884 GO:0042910 xenobiotic transmembrane transporter activity 1/250 32/18639 0.03125 2.329875 0.351098397385514 0.514307402972884 GO:0043425 bHLH transcription factor binding 1/250 32/18639 0.03125 2.329875 0.351098397385514 0.514307402972884 GO:0047498 calcium-dependent phospholipase A2 activity 1/250 32/18639 0.03125 2.329875 0.351098397385514 0.514307402972884 GO:0051059 NF-kappaB binding 1/250 32/18639 0.03125 2.329875 0.351098397385514 0.514307402972884 GO:0070717 poly-purine tract binding 1/250 32/18639 0.03125 2.329875 0.351098397385514 0.514307402972884 GO:0120015 sterol transfer activity 1/250 32/18639 0.03125 2.329875 0.351098397385514 0.514307402972884 GO:0140142 nucleocytoplasmic carrier activity 1/250 32/18639 0.03125 2.329875 0.351098397385514 0.514307402972884 GO:0160041 neuropeptide activity 1/250 32/18639 0.03125 2.329875 0.351098397385514 0.514307402972884 GO:0030296 protein tyrosine kinase activator activity 1/250 33/18639 0.0303030303030303 2.25927272727273 0.359816911958182 0.5227206835196 GO:0071889 14-3-3 protein binding 1/250 33/18639 0.0303030303030303 2.25927272727273 0.359816911958182 0.5227206835196 GO:0140311 protein sequestering activity 1/250 33/18639 0.0303030303030303 2.25927272727273 0.359816911958182 0.5227206835196 GO:0016410 N-acyltransferase activity 2/250 94/18639 0.0212765957446809 1.58629787234043 0.360078489421396 0.5227206835196 GO:0030332 cyclin binding 1/250 34/18639 0.0294117647058824 2.19282352941176 0.368418748570589 0.533628949723319 GO:0000287 magnesium ion binding 4/250 230/18639 0.0173913043478261 1.29662608695652 0.372011396873063 0.537627208903801 GO:0004623 phospholipase A2 activity 1/250 35/18639 0.0285714285714286 2.13017142857143 0.376905462510785 0.542273783478769 GO:0005154 epidermal growth factor receptor binding 1/250 35/18639 0.0285714285714286 2.13017142857143 0.376905462510785 0.542273783478769 GO:0004190 aspartic-type endopeptidase activity 1/250 36/18639 0.0277777777777778 2.071 0.385278588417703 0.551862457024028 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/250 36/18639 0.0277777777777778 2.071 0.385278588417703 0.551862457024028 GO:0016874 ligase activity 3/250 167/18639 0.0179640718562874 1.33932934131737 0.38867551385819 0.555496420248652 GO:0022829 wide pore channel activity 1/250 37/18639 0.027027027027027 2.01502702702703 0.393539640554218 0.558739797358296 GO:0043394 proteoglycan binding 1/250 37/18639 0.027027027027027 2.01502702702703 0.393539640554218 0.558739797358296 GO:0070001 aspartic-type peptidase activity 1/250 37/18639 0.027027027027027 2.01502702702703 0.393539640554218 0.558739797358296 GO:0005501 retinoid binding 1/250 38/18639 0.0263157894736842 1.962 0.401690113076605 0.566576011020713 GO:0019840 isoprenoid binding 1/250 38/18639 0.0263157894736842 1.962 0.401690113076605 0.566576011020713 GO:0042887 amide transmembrane transporter activity 1/250 38/18639 0.0263157894736842 1.962 0.401690113076605 0.566576011020713 GO:0000217 DNA secondary structure binding 1/250 39/18639 0.0256410256410256 1.91169230769231 0.409731480300456 0.575405513639335 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/250 39/18639 0.0256410256410256 1.91169230769231 0.409731480300456 0.575405513639335 GO:0008013 beta-catenin binding 2/250 106/18639 0.0188679245283019 1.40671698113208 0.417030823310316 0.580240252125058 GO:0004721 phosphoprotein phosphatase activity 3/250 175/18639 0.0171428571428571 1.27810285714286 0.417478552558034 0.580240252125058 GO:0030331 nuclear estrogen receptor binding 1/250 40/18639 0.025 1.8639 0.417665196963084 0.580240252125058 GO:0050997 quaternary ammonium group binding 1/250 40/18639 0.025 1.8639 0.417665196963084 0.580240252125058 GO:0071949 FAD binding 1/250 40/18639 0.025 1.8639 0.417665196963084 0.580240252125058 GO:0004812 aminoacyl-tRNA ligase activity 1/250 41/18639 0.024390243902439 1.81843902439024 0.425492698482479 0.586073098549427 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/250 41/18639 0.024390243902439 1.81843902439024 0.425492698482479 0.586073098549427 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/250 41/18639 0.024390243902439 1.81843902439024 0.425492698482479 0.586073098549427 GO:0017080 sodium channel regulator activity 1/250 41/18639 0.024390243902439 1.81843902439024 0.425492698482479 0.586073098549427 GO:0031492 nucleosomal DNA binding 1/250 42/18639 0.0238095238095238 1.77514285714286 0.433215401212847 0.594176537544584 GO:0042056 chemoattractant activity 1/250 42/18639 0.0238095238095238 1.77514285714286 0.433215401212847 0.594176537544584 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/250 43/18639 0.0232558139534884 1.73386046511628 0.440834702696784 0.599535195667627 GO:0008200 ion channel inhibitor activity 1/250 43/18639 0.0232558139534884 1.73386046511628 0.440834702696784 0.599535195667627 GO:0008375 acetylglucosaminyltransferase activity 1/250 43/18639 0.0232558139534884 1.73386046511628 0.440834702696784 0.599535195667627 GO:0048156 tau protein binding 1/250 43/18639 0.0232558139534884 1.73386046511628 0.440834702696784 0.599535195667627 GO:0001223 transcription coactivator binding 1/250 44/18639 0.0227272727272727 1.69445454545455 0.448351981914132 0.604666764752671 GO:0016248 channel inhibitor activity 1/250 44/18639 0.0227272727272727 1.69445454545455 0.448351981914132 0.604666764752671 GO:0019205 nucleobase-containing compound kinase activity 1/250 44/18639 0.0227272727272727 1.69445454545455 0.448351981914132 0.604666764752671 GO:0030547 signaling receptor inhibitor activity 1/250 44/18639 0.0227272727272727 1.69445454545455 0.448351981914132 0.604666764752671 GO:0008009 chemokine activity 1/250 45/18639 0.0222222222222222 1.6568 0.455768599527548 0.609578706614485 GO:0046915 transition metal ion transmembrane transporter activity 1/250 45/18639 0.0222222222222222 1.6568 0.455768599527548 0.609578706614485 GO:0140303 intramembrane lipid transporter activity 1/250 45/18639 0.0222222222222222 1.6568 0.455768599527548 0.609578706614485 GO:0141110 transporter inhibitor activity 1/250 45/18639 0.0222222222222222 1.6568 0.455768599527548 0.609578706614485 GO:0017124 SH3 domain binding 2/250 115/18639 0.0173913043478261 1.29662608695652 0.45803729000282 0.611347292028557 GO:0004180 carboxypeptidase activity 1/250 46/18639 0.0217391304347826 1.62078260869565 0.463085898124844 0.615542160881994 GO:0030291 protein serine/threonine kinase inhibitor activity 1/250 46/18639 0.0217391304347826 1.62078260869565 0.463085898124844 0.615542160881994 GO:0005504 fatty acid binding 1/250 47/18639 0.0212765957446809 1.58629787234043 0.47030520245813 0.623854539605651 GO:0022853 active monoatomic ion transmembrane transporter activity 2/250 118/18639 0.0169491525423729 1.26366101694915 0.471334576941158 0.623938804721287 GO:0140693 molecular condensate scaffold activity 1/250 48/18639 0.0208333333333333 1.55325 0.47742781967981 0.630712416182325 GO:0003697 single-stranded DNA binding 2/250 121/18639 0.0165289256198347 1.2323305785124 0.484435114946007 0.633518128675602 GO:0015108 chloride transmembrane transporter activity 2/250 121/18639 0.0165289256198347 1.2323305785124 0.484435114946007 0.633518128675602 GO:0030695 GTPase regulator activity 7/250 489/18639 0.0143149284253579 1.06726380368098 0.484453284657414 0.633518128675602 GO:0035254 glutamate receptor binding 1/250 49/18639 0.0204081632653061 1.52155102040816 0.484455039575461 0.633518128675602 GO:0060590 ATPase regulator activity 1/250 49/18639 0.0204081632653061 1.52155102040816 0.484455039575461 0.633518128675602 GO:0060589 nucleoside-triphosphatase regulator activity 7/250 490/18639 0.0142857142857143 1.06508571428571 0.486597216361756 0.635033942969079 GO:0048020 CCR chemokine receptor binding 1/250 50/18639 0.02 1.49112 0.491388134793649 0.639993417493342 GO:0005096 GTPase activator activity 4/250 271/18639 0.014760147601476 1.10045756457565 0.494040206077763 0.642152863433068 GO:0005048 signal sequence binding 1/250 51/18639 0.0196078431372549 1.46188235294118 0.498228361072717 0.645001044595141 GO:0030544 Hsp70 protein binding 1/250 51/18639 0.0196078431372549 1.46188235294118 0.498228361072717 0.645001044595141 GO:0005126 cytokine receptor binding 4/250 275/18639 0.0145454545454545 1.08445090909091 0.505473953327335 0.653072347698916 GO:0042826 histone deacetylase binding 2/250 127/18639 0.015748031496063 1.17411023622047 0.510025164822003 0.657637238473082 GO:0005246 calcium channel regulator activity 1/250 53/18639 0.0188679245283019 1.40671698113208 0.511635146555543 0.658399013296575 GO:0141003 histone H2AX kinase activity 5/250 354/18639 0.0141242937853107 1.05305084745763 0.516485480148053 0.660275879696369 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/250 54/18639 0.0185185185185185 1.38066666666667 0.518204134684302 0.660275879696369 GO:0017069 snRNA binding 1/250 54/18639 0.0185185185185185 1.38066666666667 0.518204134684302 0.660275879696369 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/250 54/18639 0.0185185185185185 1.38066666666667 0.518204134684302 0.660275879696369 GO:0050661 NADP binding 1/250 54/18639 0.0185185185185185 1.38066666666667 0.518204134684302 0.660275879696369 GO:0140996 histone H3 kinase activity 5/250 357/18639 0.0140056022408964 1.04420168067227 0.523966138656579 0.66590684175517 GO:0008374 O-acyltransferase activity 1/250 55/18639 0.0181818181818182 1.35556363636364 0.524685112156937 0.66590684175517 GO:0031072 heat shock protein binding 2/250 131/18639 0.0152671755725191 1.13825954198473 0.526618949113706 0.667050668877361 GO:0030170 pyridoxal phosphate binding 1/250 56/18639 0.0178571428571429 1.33135714285714 0.531079253459174 0.670473628199844 GO:0035173 histone kinase activity 5/250 360/18639 0.0138888888888889 1.0355 0.531397055167678 0.670473628199844 GO:0070279 vitamin B6 binding 1/250 57/18639 0.0175438596491228 1.308 0.537387717465804 0.676710459031012 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/250 58/18639 0.0172413793103448 1.28544827586207 0.543611647647353 0.683216195292199 GO:0015459 potassium channel regulator activity 1/250 59/18639 0.0169491525423729 1.26366101694915 0.549752172274023 0.688255626529107 GO:0070888 E-box binding 1/250 59/18639 0.0169491525423729 1.26366101694915 0.549752172274023 0.688255626529107 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/250 60/18639 0.0166666666666667 1.2426 0.555810404616946 0.694494238650961 GO:0030295 protein kinase activator activity 2/250 139/18639 0.0143884892086331 1.07274820143885 0.558654052058723 0.6953574520808 GO:0070851 growth factor receptor binding 2/250 139/18639 0.0143884892086331 1.07274820143885 0.558654052058723 0.6953574520808 GO:0015026 coreceptor activity 1/250 61/18639 0.0163934426229508 1.22222950819672 0.561787443146778 0.696573298028443 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/250 61/18639 0.0163934426229508 1.22222950819672 0.561787443146778 0.696573298028443 GO:0046873 metal ion transmembrane transporter activity 6/250 450/18639 0.0133333333333333 0.99408 0.5631706472465 0.696950647741837 GO:0019955 cytokine binding 2/250 144/18639 0.0138888888888889 1.0355 0.577881603537047 0.713788749301974 GO:0120013 lipid transfer activity 1/250 65/18639 0.0153846153846154 1.14701538461538 0.584905121434651 0.72108532146333 GO:0019209 kinase activator activity 2/250 148/18639 0.0135135135135135 1.00751351351351 0.592819126085865 0.72944981990756 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/250 229/18639 0.0131004366812227 0.97671615720524 0.595662480575041 0.731183250882398 GO:0008509 monoatomic anion transmembrane transporter activity 2/250 149/18639 0.0134228187919463 1.00075167785235 0.596491599404062 0.731183250882398 GO:0005085 guanyl-nucleotide exchange factor activity 3/250 230/18639 0.0130434782608696 0.972469565217391 0.59861822176934 0.731698455969439 GO:0019842 vitamin binding 2/250 150/18639 0.0133333333333333 0.99408 0.600139296290001 0.731698455969439 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/250 68/18639 0.0147058823529412 1.09641176470588 0.601442538885096 0.731698455969439 GO:0030145 manganese ion binding 1/250 68/18639 0.0147058823529412 1.09641176470588 0.601442538885096 0.731698455969439 GO:0002039 p53 binding 1/250 69/18639 0.0144927536231884 1.08052173913043 0.606807859292114 0.736838114854709 GO:0042379 chemokine receptor binding 1/250 72/18639 0.0138888888888889 1.0355 0.622475998454318 0.754445581616303 GO:0004521 RNA endonuclease activity 1/250 73/18639 0.0136986301369863 1.02131506849315 0.627559264484717 0.757763149265659 GO:0043539 protein serine/threonine kinase activator activity 1/250 73/18639 0.0136986301369863 1.02131506849315 0.627559264484717 0.757763149265659 GO:0003684 damaged DNA binding 1/250 74/18639 0.0135135135135135 1.00751351351351 0.632574355720246 0.760973992169979 GO:0031491 nucleosome binding 1/250 74/18639 0.0135135135135135 1.00751351351351 0.632574355720246 0.760973992169979 GO:0099106 ion channel regulator activity 2/250 160/18639 0.0125 0.93195 0.635255936264284 0.762779432763433 GO:0019003 GDP binding 1/250 75/18639 0.0133333333333333 0.99408 0.637522182871872 0.764080389861279 GO:0017022 myosin binding 1/250 76/18639 0.0131578947368421 0.981 0.642403644533261 0.768505100682383 GO:0003724 RNA helicase activity 1/250 77/18639 0.012987012987013 0.96825974025974 0.647219627341357 0.772835266658995 GO:0140713 histone chaperone activity 2/250 164/18639 0.0121951219512195 0.909219512195122 0.64861377603388 0.77307103195182 GO:0015399 primary active transmembrane transporter activity 2/250 166/18639 0.0120481927710843 0.898265060240964 0.65514642533943 0.779419135855013 GO:0008186 ATP-dependent activity, acting on RNA 1/250 79/18639 0.0126582278481013 0.943746835443038 0.656658644110505 0.779782139881225 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/250 167/18639 0.0119760479041916 0.89288622754491 0.658376375781627 0.780387410559507 GO:0016247 channel regulator activity 2/250 168/18639 0.0119047619047619 0.887571428571429 0.661582158097352 0.782751051521775 GO:0140097 catalytic activity, acting on DNA 4/250 336/18639 0.0119047619047619 0.887571428571429 0.662843035360089 0.782809142308259 GO:0001618 virus receptor activity 1/250 81/18639 0.0123456790123457 0.920444444444444 0.665846093109865 0.783491031236744 GO:0030971 receptor tyrosine kinase binding 1/250 81/18639 0.0123456790123457 0.920444444444444 0.665846093109865 0.783491031236744 GO:0141108 transporter regulator activity 2/250 170/18639 0.0117647058823529 0.877129411764706 0.667921478591294 0.784504136672684 GO:0140272 exogenous protein binding 1/250 82/18639 0.0121951219512195 0.909219512195122 0.670347573696271 0.785924741574939 GO:0001540 amyloid-beta binding 1/250 83/18639 0.0120481927710843 0.898265060240964 0.67478865288881 0.788270288908085 GO:0005254 chloride channel activity 1/250 83/18639 0.0120481927710843 0.898265060240964 0.67478865288881 0.788270288908085 GO:0051117 ATPase binding 1/250 84/18639 0.0119047619047619 0.887571428571429 0.679170137949049 0.79185994048798 GO:0003823 antigen binding 2/250 174/18639 0.0114942528735632 0.856965517241379 0.680313106765989 0.79185994048798 GO:0003730 mRNA 3'-UTR binding 3/250 262/18639 0.0114503816793893 0.85369465648855 0.685601506772172 0.796580167940329 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/250 86/18639 0.0116279069767442 0.86693023255814 0.68775750113096 0.79765053093465 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/250 88/18639 0.0113636363636364 0.847227272727273 0.696115908964317 0.80589762937446 GO:0016757 glycosyltransferase activity 3/250 267/18639 0.0112359550561798 0.837707865168539 0.697845094575731 0.806454259563368 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/250 91/18639 0.010989010989011 0.819296703296703 0.708237486472613 0.81700252903805 GO:0052689 carboxylic ester hydrolase activity 1/250 92/18639 0.0108695652173913 0.810391304347826 0.712170019812157 0.820074568268544 GO:0140597 protein carrier chaperone 2/250 188/18639 0.0106382978723404 0.793148936170213 0.72073880894097 0.828464894263108 GO:0004896 cytokine receptor activity 1/250 96/18639 0.0104166666666667 0.776625 0.727379209759559 0.83313292465368 GO:0016407 acetyltransferase activity 1/250 96/18639 0.0104166666666667 0.776625 0.727379209759559 0.83313292465368 GO:0030527 structural constituent of chromatin 1/250 98/18639 0.0102040816326531 0.760775510204082 0.734680894539595 0.838522717089361 GO:0042626 ATPase-coupled transmembrane transporter activity 1/250 98/18639 0.0102040816326531 0.760775510204082 0.734680894539595 0.838522717089361 GO:0015171 amino acid transmembrane transporter activity 1/250 102/18639 0.00980392156862745 0.730941176470588 0.748705035281265 0.853021962595585 GO:0005253 monoatomic anion channel activity 1/250 103/18639 0.00970873786407767 0.723844660194175 0.752094134983465 0.855374667604434 GO:0008168 methyltransferase activity 2/250 204/18639 0.00980392156862745 0.730941176470588 0.761594401869186 0.863589461634957 GO:0000149 SNARE binding 1/250 106/18639 0.00943396226415094 0.703358490566038 0.761990701442609 0.863589461634957 GO:0019888 protein phosphatase regulator activity 1/250 107/18639 0.00934579439252336 0.696785046728972 0.765201316272337 0.865709370073432 GO:0051015 actin filament binding 2/250 209/18639 0.00956937799043062 0.713454545454545 0.773259510846902 0.873296580431991 GO:1902936 phosphatidylinositol bisphosphate binding 1/250 111/18639 0.00900900900900901 0.671675675675676 0.777618125213846 0.876686402946151 GO:0016741 transferase activity, transferring one-carbon groups 2/250 215/18639 0.00930232558139535 0.693544186046512 0.786599789863951 0.885267359324238 GO:0019208 phosphatase regulator activity 1/250 117/18639 0.00854700854700855 0.637230769230769 0.79502761102956 0.891645549869958 GO:1990782 protein tyrosine kinase binding 1/250 117/18639 0.00854700854700855 0.637230769230769 0.79502761102956 0.891645549869958 GO:0005543 phospholipid binding 5/250 497/18639 0.0100603621730382 0.750060362173038 0.799955030516205 0.895616897250379 GO:0004540 RNA nuclease activity 1/250 121/18639 0.00826446280991736 0.616165289256198 0.805872856302657 0.900681427632381 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/250 122/18639 0.00819672131147541 0.611114754098361 0.808493646124686 0.902049905693519 GO:0016887 ATP hydrolysis activity 4/250 417/18639 0.00959232613908873 0.715165467625899 0.813694038644772 0.906286808559522 GO:0004519 endonuclease activity 1/250 127/18639 0.0078740157480315 0.587055118110236 0.821078311341936 0.912937330683117 GO:0035591 signaling adaptor activity 1/250 129/18639 0.00775193798449612 0.577953488372093 0.825878395329979 0.916696638115407 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/250 130/18639 0.00769230769230769 0.573507692307692 0.828230118785814 0.917730114469358 GO:0005262 calcium channel activity 1/250 131/18639 0.00763358778625954 0.569129770992366 0.830550204706369 0.918725055206018 GO:0004674 protein serine/threonine kinase activity 4/250 433/18639 0.0092378752886836 0.688739030023095 0.835862087322318 0.923020356256782 GO:0016779 nucleotidyltransferase activity 1/250 136/18639 0.00735294117647059 0.548205882352941 0.841690712398954 0.927542125051921 GO:0035402 histone H3T11 kinase activity 2/250 247/18639 0.00809716599190283 0.603692307692308 0.846693995777827 0.927542125051921 GO:0042393 histone binding 2/250 247/18639 0.00809716599190283 0.603692307692308 0.846693995777827 0.927542125051921 GO:0140101 catalytic activity, acting on a tRNA 1/250 139/18639 0.00719424460431655 0.536374100719424 0.848021643065674 0.927542125051921 GO:0140767 enzyme-substrate adaptor activity 1/250 139/18639 0.00719424460431655 0.536374100719424 0.848021643065674 0.927542125051921 GO:0003779 actin binding 4/250 443/18639 0.0090293453724605 0.673191873589165 0.848571820287439 0.927542125051921 GO:0008194 UDP-glycosyltransferase activity 1/250 145/18639 0.00689655172413793 0.514179310344828 0.859936890865754 0.938377080235265 GO:0015085 calcium ion transmembrane transporter activity 1/250 147/18639 0.00680272108843537 0.507183673469388 0.863698115194595 0.940892044545883 GO:0000510 H3-H4 histone complex chaperone activity 1/250 151/18639 0.00662251655629139 0.493748344370861 0.870921414828398 0.94113987734061 GO:0140584 chromatin extrusion motor activity 1/250 151/18639 0.00662251655629139 0.493748344370861 0.870921414828398 0.94113987734061 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/250 151/18639 0.00662251655629139 0.493748344370861 0.870921414828398 0.94113987734061 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/250 151/18639 0.00662251655629139 0.493748344370861 0.870921414828398 0.94113987734061 GO:0015616 DNA translocase activity 1/250 152/18639 0.00657894736842105 0.4905 0.872666852209018 0.94113987734061 GO:0140674 ATP-dependent histone chaperone activity 1/250 152/18639 0.00657894736842105 0.4905 0.872666852209018 0.94113987734061 GO:0061775 cohesin loader activity 1/250 153/18639 0.0065359477124183 0.487294117647059 0.874388780426021 0.941425253592016 GO:0004386 helicase activity 1/250 155/18639 0.00645161290322581 0.481006451612903 0.877763366709065 0.943486081354503 GO:0140658 ATP-dependent chromatin remodeler activity 1/250 158/18639 0.00632911392405063 0.471873417721519 0.882656676328571 0.947169788884148 GO:0003689 DNA clamp loader activity 1/250 160/18639 0.00625 0.465975 0.885809990006833 0.948977203224567 GO:0140098 catalytic activity, acting on RNA 3/250 387/18639 0.00775193798449612 0.577953488372093 0.894606917691695 0.956814683491448 GO:0140030 modification-dependent protein binding 1/250 173/18639 0.00578034682080925 0.430959537572254 0.904346714458823 0.965633020727934 GO:1901981 phosphatidylinositol phosphate binding 1/250 185/18639 0.00540540540540541 0.403005405405405 0.918784145775559 0.979429963978566 GO:0051020 GTPase binding 2/250 315/18639 0.00634920634920635 0.473371428571429 0.926591296998604 0.982386725749985 GO:0016758 hexosyltransferase activity 1/250 197/18639 0.0050761421319797 0.378456852791878 0.931049851898538 0.982386725749985 GO:0004518 nuclease activity 1/250 209/18639 0.00478468899521531 0.356727272727273 0.941469397945614 0.982386725749985 GO:0005216 monoatomic ion channel activity 3/250 448/18639 0.00669642857142857 0.499258928571429 0.941735382052455 0.982386725749985 GO:0008094 ATP-dependent activity, acting on DNA 1/250 210/18639 0.00476190476190476 0.355028571428571 0.942263356193774 0.982386725749985 GO:0005261 monoatomic cation channel activity 2/250 341/18639 0.00586510263929619 0.437278592375367 0.945139653687128 0.982386725749985 GO:0045182 translation regulator activity 2/250 356/18639 0.00561797752808989 0.41885393258427 0.953720078941088 0.982386725749985 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/250 243/18639 0.00411522633744856 0.306814814814815 0.963226796529171 0.982386725749985 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0004711 ribosomal protein S6 kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0035175 histone H3S10 kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0035979 histone H2AXS139 kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0044022 histone H3S28 kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0044023 histone H4S1 kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0044024 histone H2AS1 kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0044025 histone H2BS14 kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0072354 histone H3T3 kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0072371 histone H2AS121 kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0140823 histone H2BS36 kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0140855 histone H3S57 kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0140995 histone H2A kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0140997 histone H4 kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0140998 histone H2B kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:1990244 histone H2AT120 kinase activity 1/250 245/18639 0.00408163265306122 0.304310204081633 0.964219520957094 0.982386725749985 GO:0004677 DNA-dependent protein kinase activity 1/250 246/18639 0.0040650406504065 0.303073170731707 0.964705827348348 0.982386725749985 GO:0140857 histone H3T45 kinase activity 1/250 246/18639 0.0040650406504065 0.303073170731707 0.964705827348348 0.982386725749985 GO:0035403 histone H3T6 kinase activity 1/250 247/18639 0.00404858299595142 0.301846153846154 0.965185550240911 0.982386725749985 GO:0004679 AMP-activated protein kinase activity 1/250 248/18639 0.00403225806451613 0.300629032258065 0.965658778407493 0.982386725749985 GO:0008017 microtubule binding 1/250 276/18639 0.0036231884057971 0.270130434782609 0.976597771588173 0.99130508126206 GO:0031267 small GTPase binding 1/250 283/18639 0.00353356890459364 0.263448763250883 0.978739296665969 0.99130508126206 GO:0035091 phosphatidylinositol binding 1/250 284/18639 0.00352112676056338 0.262521126760563 0.979028857345502 0.99130508126206 GO:0016755 aminoacyltransferase activity 2/250 496/18639 0.00403225806451613 0.300629032258065 0.991069576082462 0.997860283111266 GO:0061630 ubiquitin protein ligase activity 1/250 353/18639 0.0028328611898017 0.211206798866856 0.991873577965782 0.997860283111266 GO:0106310 protein serine kinase activity 1/250 361/18639 0.00277008310249307 0.206526315789474 0.99272115883719 0.997860283111266 GO:0046982 protein heterodimerization activity 1/250 369/18639 0.002710027100271 0.202048780487805 0.993480654083916 0.997860283111266 GO:0061659 ubiquitin-like protein ligase activity 1/250 372/18639 0.00268817204301075 0.20041935483871 0.993744647993377 0.997860283111266 GO:0015631 tubulin binding 1/250 385/18639 0.0025974025974026 0.193651948051948 0.994770932389559 0.997860283111266 GO:0004842 ubiquitin-protein transferase activity 1/250 449/18639 0.0022271714922049 0.166048997772828 0.997839978899769 0.998574375024338 GO:0019787 ubiquitin-like protein transferase activity 1/250 479/18639 0.00208768267223382 0.155649269311065 0.998574375024338 0.998574375024338