ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0045296 cadherin binding 13/199 334/18639 0.0389221556886228 3.64557819035296 6.48031045826516e-05 0.0335680081738136 GO:0098631 cell adhesion mediator activity 6/199 76/18639 0.0789473684210526 7.39447236180905 0.000161383352779082 0.0417982883697823 GO:0098632 cell-cell adhesion mediator activity 5/199 55/18639 0.0909090909090909 8.51484696208314 0.00029757121123547 0.0513806291399912 GO:0034236 protein kinase A catalytic subunit binding 3/199 14/18639 0.214285714285714 20.0707106963388 0.000400081994311444 0.0518106182633321 GO:0005159 insulin-like growth factor receptor binding 3/199 16/18639 0.1875 17.5618718592965 0.000605893398756293 0.062770556111152 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/199 41/18639 0.0975609756097561 9.13788454467459 0.000937252652373014 0.069356696275603 GO:0042169 SH2 domain binding 4/199 41/18639 0.0975609756097561 9.13788454467459 0.000937252652373014 0.069356696275603 GO:0004620 phospholipase activity 6/199 109/18639 0.055045871559633 5.15577889447236 0.00111817727566359 0.0724019785992174 GO:1990782 protein tyrosine kinase binding 6/199 117/18639 0.0512820512820513 4.80324700425203 0.00161003669683167 0.0835528442558198 GO:0030971 receptor tyrosine kinase binding 5/199 81/18639 0.0617283950617284 5.78168620882189 0.0017528262966823 0.0835528442558198 GO:0016849 phosphorus-oxygen lyase activity 3/199 23/18639 0.130434782608696 12.2169543369019 0.00181360748466658 0.0835528442558198 GO:0004860 protein kinase inhibitor activity 5/199 84/18639 0.0595238095238095 5.57519741564968 0.0020584534494662 0.0835528442558198 GO:0005080 protein kinase C binding 4/199 52/18639 0.0769230769230769 7.20487050637804 0.00228712267253637 0.0835528442558198 GO:0003925 G protein activity 4/199 54/18639 0.0740740740740741 6.93802345058626 0.00262788580230425 0.0835528442558198 GO:0016298 lipase activity 6/199 130/18639 0.0461538461538462 4.32292230382683 0.00273985339640152 0.0835528442558198 GO:0003735 structural constituent of ribosome 7/199 175/18639 0.04 3.74653266331658 0.00278348029425961 0.0835528442558198 GO:0019210 kinase inhibitor activity 5/199 90/18639 0.0555555555555556 5.2035175879397 0.00278381023744574 0.0835528442558198 GO:0001217 DNA-binding transcription repressor activity 9/199 278/18639 0.0323741007194245 3.03226564477062 0.00307779481692777 0.0835528442558198 GO:0051219 phosphoprotein binding 5/199 93/18639 0.0537634408602151 5.03566218187713 0.00320863338658666 0.0835528442558198 GO:0045499 chemorepellent activity 3/199 28/18639 0.107142857142857 10.0353553481694 0.00322597854269574 0.0835528442558198 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/199 10/18639 0.2 18.7326633165829 0.00482405271212177 0.118993300232337 GO:0004857 enzyme inhibitor activity 11/199 416/18639 0.0264423076923077 2.47667423656745 0.00522630207176969 0.122472373059743 GO:0004143 ATP-dependent diacylglycerol kinase activity 2/199 11/18639 0.181818181818182 17.0296939241663 0.00585479854931569 0.122472373059743 GO:0010854 adenylate cyclase regulator activity 2/199 11/18639 0.181818181818182 17.0296939241663 0.00585479854931569 0.122472373059743 GO:0019887 protein kinase regulator activity 8/199 255/18639 0.0313725490196078 2.93845699083654 0.00621002606924347 0.122472373059743 GO:0046982 protein heterodimerization activity 10/199 369/18639 0.02710027100271 2.53830126240961 0.00645033352801381 0.122472373059743 GO:0097110 scaffold protein binding 4/199 70/18639 0.0571428571428571 5.35218951902369 0.00667705604386918 0.122472373059743 GO:0005516 calmodulin binding 7/199 207/18639 0.0338164251207729 3.16735853178938 0.00692373194181525 0.122472373059743 GO:0008603 cAMP-dependent protein kinase regulator activity 2/199 12/18639 0.166666666666667 15.6105527638191 0.00697662827756636 0.122472373059743 GO:0005525 GTP binding 10/199 378/18639 0.0264550264550265 2.47786551806652 0.00758622660733532 0.122472373059743 GO:0005109 frizzled binding 3/199 38/18639 0.0789473684210526 7.39447236180905 0.00768374538408269 0.122472373059743 GO:0005178 integrin binding 6/199 161/18639 0.0372670807453416 3.49055838197197 0.00772053163216516 0.122472373059743 GO:0008083 growth factor activity 6/199 162/18639 0.037037037037037 3.46901172529313 0.00794816296701395 0.122472373059743 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 2/199 13/18639 0.153846153846154 14.4097410127561 0.00818749941135512 0.122472373059743 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 8/199 268/18639 0.0298507462686567 2.79591989799745 0.00827516034187454 0.122472373059743 GO:0005096 GTPase activator activity 8/199 271/18639 0.029520295202952 2.76496875521519 0.00881735633613363 0.124041406986349 GO:0030331 nuclear estrogen receptor binding 3/199 40/18639 0.075 7.02474874371859 0.00886010049902495 0.124041406986349 GO:0044548 S100 protein binding 2/199 14/18639 0.142857142857143 13.3804737975592 0.00948540231419574 0.12930101049351 GO:0031492 nucleosomal DNA binding 3/199 42/18639 0.0714285714285714 6.69023689877961 0.0101362228645907 0.129653785410937 GO:0008200 ion channel inhibitor activity 3/199 43/18639 0.0697674418604651 6.53464999415683 0.0108121888452716 0.129653785410937 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 2/199 15/18639 0.133333333333333 12.4884422110553 0.0108683597358154 0.129653785410937 GO:0120283 protein serine/threonine kinase binding 2/199 15/18639 0.133333333333333 12.4884422110553 0.0108683597358154 0.129653785410937 GO:0019001 guanyl nucleotide binding 10/199 400/18639 0.025 2.34158291457286 0.0110143737145727 0.129653785410937 GO:0032561 guanyl ribonucleotide binding 10/199 400/18639 0.025 2.34158291457286 0.0110143737145727 0.129653785410937 GO:0001046 core promoter sequence-specific DNA binding 3/199 44/18639 0.0681818181818182 6.38613522156236 0.011513656619504 0.129653785410937 GO:0016248 channel inhibitor activity 3/199 44/18639 0.0681818181818182 6.38613522156236 0.011513656619504 0.129653785410937 GO:0019207 kinase regulator activity 8/199 287/18639 0.0278745644599303 2.61082415562131 0.0121692235893459 0.130392507185607 GO:0141110 transporter inhibitor activity 3/199 45/18639 0.0666666666666667 6.24422110552764 0.0122407817369019 0.130392507185607 GO:0022841 potassium ion leak channel activity 2/199 16/18639 0.125 11.7079145728643 0.0123344263553952 0.130392507185607 GO:0030291 protein serine/threonine kinase inhibitor activity 3/199 46/18639 0.0652173913043478 6.10847716845095 0.0129937054806763 0.134614788779806 GO:0001784 phosphotyrosine residue binding 3/199 47/18639 0.0638297872340425 5.97850956912221 0.0137725552350486 0.137815649001728 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/199 17/18639 0.117647058823529 11.019213715637 0.0138816883307951 0.137815649001728 GO:0008081 phosphoric diester hydrolase activity 4/199 87/18639 0.0459770114942529 4.30635938312251 0.0141008289519143 0.137815649001728 GO:0001664 G protein-coupled receptor binding 8/199 297/18639 0.0269360269360269 2.52291761839501 0.014691934916095 0.140933746046985 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 11/199 484/18639 0.0227272727272727 2.12871174052079 0.0151461632339586 0.142649319185282 GO:0098641 cadherin binding involved in cell-cell adhesion 2/199 18/18639 0.111111111111111 10.4070351758794 0.0155082628536867 0.143451431396602 GO:0001216 DNA-binding transcription activator activity 11/199 491/18639 0.0224032586558045 2.09836350796754 0.0166713153253388 0.148599503567517 GO:0008301 DNA binding, bending 2/199 19/18639 0.105263157894737 9.85929648241206 0.0172122977105232 0.148599503567517 GO:0022840 leak channel activity 2/199 19/18639 0.105263157894737 9.85929648241206 0.0172122977105232 0.148599503567517 GO:0022842 narrow pore channel activity 2/199 19/18639 0.105263157894737 9.85929648241206 0.0172122977105232 0.148599503567517 GO:0001614 purinergic nucleotide receptor activity 2/199 20/18639 0.1 9.36633165829146 0.0189919708492703 0.151380093837418 GO:0010851 cyclase regulator activity 2/199 20/18639 0.1 9.36633165829146 0.0189919708492703 0.151380093837418 GO:0016502 nucleotide receptor activity 2/199 20/18639 0.1 9.36633165829146 0.0189919708492703 0.151380093837418 GO:0051018 protein kinase A binding 3/199 53/18639 0.0566037735849057 5.30169716507064 0.0189955716205255 0.151380093837418 GO:0140296 general transcription initiation factor binding 3/199 53/18639 0.0566037735849057 5.30169716507064 0.0189955716205255 0.151380093837418 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/199 21/18639 0.0952380952380952 8.92031586503948 0.0208454899518282 0.157358490398772 GO:0009975 cyclase activity 2/199 21/18639 0.0952380952380952 8.92031586503948 0.0208454899518282 0.157358490398772 GO:0030527 structural constituent of chromatin 4/199 98/18639 0.0408163265306122 3.82299251358835 0.0209201561517787 0.157358490398772 GO:0003779 actin binding 10/199 443/18639 0.0225733634311512 2.11429608539311 0.0209608799952033 0.157358490398772 GO:0005243 gap junction channel activity 2/199 22/18639 0.0909090909090909 8.51484696208314 0.0227710920120726 0.166132755806389 GO:0031683 G-protein beta/gamma-subunit complex binding 2/199 22/18639 0.0909090909090909 8.51484696208314 0.0227710920120726 0.166132755806389 GO:0005158 insulin receptor binding 2/199 23/18639 0.0869565217391304 8.14463622460127 0.0247670429194446 0.175934025200942 GO:0004879 nuclear receptor activity 3/199 59/18639 0.0508474576271186 4.76254152116515 0.0251698973037487 0.175934025200942 GO:0045309 protein phosphorylated amino acid binding 3/199 59/18639 0.0508474576271186 4.76254152116515 0.0251698973037487 0.175934025200942 GO:0003924 GTPase activity 8/199 331/18639 0.0241691842900302 2.2637659597079 0.0261217321102834 0.175934025200942 GO:0098531 ligand-modulated transcription factor activity 3/199 60/18639 0.05 4.68316582914573 0.0262916799004217 0.175934025200942 GO:0001091 RNA polymerase II general transcription initiation factor binding 2/199 24/18639 0.0833333333333333 7.80527638190955 0.0268316370480201 0.175934025200942 GO:0030215 semaphorin receptor binding 2/199 24/18639 0.0833333333333333 7.80527638190955 0.0268316370480201 0.175934025200942 GO:0030552 cAMP binding 2/199 24/18639 0.0833333333333333 7.80527638190955 0.0268316370480201 0.175934025200942 GO:0015271 outward rectifier potassium channel activity 2/199 25/18639 0.08 7.49306532663317 0.0289631968509898 0.187536699610159 GO:0004435 phosphatidylinositol phospholipase C activity 2/199 26/18639 0.0769230769230769 7.20487050637804 0.0311600724604825 0.199270586846049 GO:0019843 rRNA binding 3/199 65/18639 0.0461538461538462 4.32292230382683 0.0322962276074701 0.201559589164693 GO:0038024 cargo receptor activity 3/199 65/18639 0.0461538461538462 4.32292230382683 0.0322962276074701 0.201559589164693 GO:0005044 scavenger receptor activity 2/199 27/18639 0.0740740740740741 6.93802345058626 0.0334206412926641 0.206093954638095 GO:0019208 phosphatase regulator activity 4/199 117/18639 0.0341880341880342 3.20216466950135 0.0368066574964441 0.22430410097833 GO:0004629 phospholipase C activity 2/199 29/18639 0.0689655172413793 6.45953907468376 0.0381265023769404 0.229645677107618 GO:0005125 cytokine activity 6/199 234/18639 0.0256410256410256 2.40162350212601 0.0399727796120485 0.23799884872461 GO:0047499 calcium-independent phospholipase A2 activity 2/199 31/18639 0.0645161290322581 6.04279461825255 0.0430683304337226 0.253515854143958 GO:0031491 nucleosome binding 3/199 74/18639 0.0405405405405405 3.79716148309113 0.0447425463098577 0.260411674028161 GO:0047498 calcium-dependent phospholipase A2 activity 2/199 32/18639 0.0625 5.85395728643216 0.0456239545710476 0.260580062498729 GO:0005539 glycosaminoglycan binding 6/199 242/18639 0.0247933884297521 2.32223098965904 0.045777578547074 0.260580062498729 GO:0008237 metallopeptidase activity 5/199 184/18639 0.0271739130434783 2.5451988201879 0.0476824887893097 0.267822661087137 GO:0030296 protein tyrosine kinase activator activity 2/199 33/18639 0.0606060606060606 5.67656464138876 0.0482340879266541 0.267822661087137 GO:1901981 phosphatidylinositol phosphate binding 5/199 185/18639 0.027027027027027 2.53144098872742 0.0486010234405229 0.267822661087137 GO:0035591 signaling adaptor activity 4/199 129/18639 0.0310077519379845 2.90428888629192 0.0496217284232941 0.270569003402803 GO:0051427 hormone receptor binding 2/199 34/18639 0.0588235294117647 5.5096068578185 0.0508972882772314 0.274633284662561 GO:0004623 phospholipase A2 activity 2/199 35/18639 0.0571428571428571 5.35218951902369 0.0536121377064603 0.28629986940151 GO:0005484 SNAP receptor activity 2/199 36/18639 0.0555555555555556 5.2035175879397 0.0563772422547131 0.297993994774912 GO:0022829 wide pore channel activity 2/199 37/18639 0.0540540540540541 5.06288197745484 0.0591912315734021 0.306610579550223 GO:0030551 cyclic nucleotide binding 2/199 37/18639 0.0540540540540541 5.06288197745484 0.0591912315734021 0.306610579550223 GO:0000146 microfilament motor activity 2/199 38/18639 0.0526315789473684 4.92964824120603 0.0620527585839198 0.318250781648222 GO:0016829 lyase activity 5/199 200/18639 0.025 2.34158291457286 0.0636319054352649 0.323150264857522 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3/199 86/18639 0.0348837209302326 3.26732499707842 0.0644805726957417 0.324280938411594 GO:0004177 aminopeptidase activity 2/199 40/18639 0.05 4.68316582914573 0.0679131517012208 0.335038215059356 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/199 40/18639 0.05 4.68316582914573 0.0679131517012208 0.335038215059356 GO:0001727 lipid kinase activity 2/199 41/18639 0.0487804878048781 4.5689422723373 0.0709094369942619 0.346519701537997 GO:0008307 structural constituent of muscle 2/199 42/18639 0.0476190476190476 4.46015793251974 0.0739480977007455 0.354676987120242 GO:0051879 Hsp90 protein binding 2/199 42/18639 0.0476190476190476 4.46015793251974 0.0739480977007455 0.354676987120242 GO:0042562 hormone binding 3/199 94/18639 0.0319148936170213 2.9892547845611 0.0795037895937919 0.367540617723092 GO:0030695 GTPase regulator activity 9/199 489/18639 0.0184049079754601 1.72386472238493 0.0796356163083095 0.367540617723092 GO:0060589 nucleoside-triphosphatase regulator activity 9/199 490/18639 0.0183673469387755 1.72034663111476 0.0804142977116597 0.367540617723092 GO:0004896 cytokine receptor activity 3/199 96/18639 0.03125 2.92697864321608 0.0834778273971392 0.367540617723092 GO:0005543 phospholipid binding 9/199 497/18639 0.0181086519114688 1.6961163968737 0.0859949162160705 0.367540617723092 GO:0099106 ion channel regulator activity 4/199 160/18639 0.025 2.34158291457286 0.0925362223361401 0.367540617723092 GO:0008238 exopeptidase activity 3/199 102/18639 0.0294117647058824 2.75480342890925 0.095895048511712 0.367540617723092 GO:0005004 GPI-linked ephrin receptor activity 2/199 49/18639 0.0408163265306122 3.82299251358835 0.0963040835777577 0.367540617723092 GO:0005008 hepatocyte growth factor receptor activity 2/199 49/18639 0.0408163265306122 3.82299251358835 0.0963040835777577 0.367540617723092 GO:0005009 insulin receptor activity 2/199 49/18639 0.0408163265306122 3.82299251358835 0.0963040835777577 0.367540617723092 GO:0005011 macrophage colony-stimulating factor receptor activity 2/199 49/18639 0.0408163265306122 3.82299251358835 0.0963040835777577 0.367540617723092 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/199 49/18639 0.0408163265306122 3.82299251358835 0.0963040835777577 0.367540617723092 GO:0005020 stem cell factor receptor activity 2/199 49/18639 0.0408163265306122 3.82299251358835 0.0963040835777577 0.367540617723092 GO:0008288 boss receptor activity 2/199 49/18639 0.0408163265306122 3.82299251358835 0.0963040835777577 0.367540617723092 GO:0036332 placental growth factor receptor activity 2/199 49/18639 0.0408163265306122 3.82299251358835 0.0963040835777577 0.367540617723092 GO:0038062 protein tyrosine kinase collagen receptor activity 2/199 49/18639 0.0408163265306122 3.82299251358835 0.0963040835777577 0.367540617723092 GO:0060175 brain-derived neurotrophic factor receptor activity 2/199 49/18639 0.0408163265306122 3.82299251358835 0.0963040835777577 0.367540617723092 GO:0005006 epidermal growth factor receptor activity 2/199 50/18639 0.04 3.74653266331658 0.0996390148335063 0.367540617723092 GO:0005007 fibroblast growth factor receptor activity 2/199 50/18639 0.04 3.74653266331658 0.0996390148335063 0.367540617723092 GO:0005017 platelet-derived growth factor receptor activity 2/199 50/18639 0.04 3.74653266331658 0.0996390148335063 0.367540617723092 GO:0005019 platelet-derived growth factor beta-receptor activity 2/199 50/18639 0.04 3.74653266331658 0.0996390148335063 0.367540617723092 GO:0004090 carbonyl reductase (NADPH) activity 1/199 10/18639 0.1 9.36633165829146 0.101802659788312 0.367540617723092 GO:0005131 growth hormone receptor binding 1/199 10/18639 0.1 9.36633165829146 0.101802659788312 0.367540617723092 GO:0008239 dipeptidyl-peptidase activity 1/199 10/18639 0.1 9.36633165829146 0.101802659788312 0.367540617723092 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/199 10/18639 0.1 9.36633165829146 0.101802659788312 0.367540617723092 GO:0015279 store-operated calcium channel activity 1/199 10/18639 0.1 9.36633165829146 0.101802659788312 0.367540617723092 GO:0042975 peroxisome proliferator activated receptor binding 1/199 10/18639 0.1 9.36633165829146 0.101802659788312 0.367540617723092 GO:0043295 glutathione binding 1/199 10/18639 0.1 9.36633165829146 0.101802659788312 0.367540617723092 GO:0070513 death domain binding 1/199 10/18639 0.1 9.36633165829146 0.101802659788312 0.367540617723092 GO:0005010 insulin-like growth factor receptor activity 2/199 51/18639 0.0392156862745098 3.67307123854567 0.103005942150393 0.367540617723092 GO:0005021 vascular endothelial growth factor receptor activity 2/199 51/18639 0.0392156862745098 3.67307123854567 0.103005942150393 0.367540617723092 GO:0005030 neurotrophin receptor activity 2/199 51/18639 0.0392156862745098 3.67307123854567 0.103005942150393 0.367540617723092 GO:0005272 sodium channel activity 2/199 51/18639 0.0392156862745098 3.67307123854567 0.103005942150393 0.367540617723092 GO:0008013 beta-catenin binding 3/199 106/18639 0.0283018867924528 2.65084858253532 0.10456698832311 0.367540617723092 GO:0016247 channel regulator activity 4/199 168/18639 0.0238095238095238 2.23007896625987 0.105770447736307 0.367540617723092 GO:0030159 signaling receptor complex adaptor activity 2/199 52/18639 0.0384615384615385 3.60243525318902 0.106403810855501 0.367540617723092 GO:0141108 transporter regulator activity 4/199 170/18639 0.0235294117647059 2.2038427431274 0.109207106280843 0.367540617723092 GO:0005003 ephrin receptor activity 2/199 53/18639 0.0377358490566038 3.53446477671376 0.109831584943147 0.367540617723092 GO:0005005 transmembrane-ephrin receptor activity 2/199 53/18639 0.0377358490566038 3.53446477671376 0.109831584943147 0.367540617723092 GO:0017046 peptide hormone binding 2/199 53/18639 0.0377358490566038 3.53446477671376 0.109831584943147 0.367540617723092 GO:0038064 collagen receptor activity 2/199 53/18639 0.0377358490566038 3.53446477671376 0.109831584943147 0.367540617723092 GO:0004016 adenylate cyclase activity 1/199 11/18639 0.0909090909090909 8.51484696208314 0.111397445912211 0.367540617723092 GO:0008432 JUN kinase binding 1/199 11/18639 0.0909090909090909 8.51484696208314 0.111397445912211 0.367540617723092 GO:0019215 intermediate filament binding 1/199 11/18639 0.0909090909090909 8.51484696208314 0.111397445912211 0.367540617723092 GO:0034056 estrogen response element binding 1/199 11/18639 0.0909090909090909 8.51484696208314 0.111397445912211 0.367540617723092 GO:0034713 type I transforming growth factor beta receptor binding 1/199 11/18639 0.0909090909090909 8.51484696208314 0.111397445912211 0.367540617723092 GO:0048407 platelet-derived growth factor binding 1/199 11/18639 0.0909090909090909 8.51484696208314 0.111397445912211 0.367540617723092 GO:0140031 phosphorylation-dependent protein binding 1/199 11/18639 0.0909090909090909 8.51484696208314 0.111397445912211 0.367540617723092 GO:1900750 oligopeptide binding 1/199 11/18639 0.0909090909090909 8.51484696208314 0.111397445912211 0.367540617723092 GO:0004222 metalloendopeptidase activity 3/199 110/18639 0.0272727272727273 2.55445408862494 0.113535921189921 0.372225361875817 GO:1902936 phosphatidylinositol bisphosphate binding 3/199 111/18639 0.027027027027027 2.53144098872742 0.115822710759177 0.377235832608175 GO:0019212 phosphatase inhibitor activity 2/199 56/18639 0.0357142857142857 3.34511844938981 0.120284253703356 0.377235832608175 GO:0010853 cyclase activator activity 1/199 12/18639 0.0833333333333333 7.80527638190955 0.120890247515361 0.377235832608175 GO:0017166 vinculin binding 1/199 12/18639 0.0833333333333333 7.80527638190955 0.120890247515361 0.377235832608175 GO:0035259 nuclear glucocorticoid receptor binding 1/199 12/18639 0.0833333333333333 7.80527638190955 0.120890247515361 0.377235832608175 GO:0045295 gamma-catenin binding 1/199 12/18639 0.0833333333333333 7.80527638190955 0.120890247515361 0.377235832608175 GO:0070410 co-SMAD binding 1/199 12/18639 0.0833333333333333 7.80527638190955 0.120890247515361 0.377235832608175 GO:0070679 inositol 1,4,5 trisphosphate binding 1/199 12/18639 0.0833333333333333 7.80527638190955 0.120890247515361 0.377235832608175 GO:0035401 histone H3Y41 kinase activity 3/199 115/18639 0.0260869565217391 2.44339086738038 0.125140607991522 0.385470022928653 GO:0140801 histone H2AXY142 kinase activity 3/199 115/18639 0.0260869565217391 2.44339086738038 0.125140607991522 0.385470022928653 GO:0004465 lipoprotein lipase activity 1/199 13/18639 0.0769230769230769 7.20487050637804 0.130282143190695 0.385470022928653 GO:0031432 titin binding 1/199 13/18639 0.0769230769230769 7.20487050637804 0.130282143190695 0.385470022928653 GO:0039706 co-receptor binding 1/199 13/18639 0.0769230769230769 7.20487050637804 0.130282143190695 0.385470022928653 GO:0070700 BMP receptor binding 1/199 13/18639 0.0769230769230769 7.20487050637804 0.130282143190695 0.385470022928653 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/199 13/18639 0.0769230769230769 7.20487050637804 0.130282143190695 0.385470022928653 GO:0097157 pre-mRNA intronic binding 1/199 13/18639 0.0769230769230769 7.20487050637804 0.130282143190695 0.385470022928653 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/199 13/18639 0.0769230769230769 7.20487050637804 0.130282143190695 0.385470022928653 GO:0070888 E-box binding 2/199 59/18639 0.0338983050847458 3.17502768077677 0.130970509720932 0.385470022928653 GO:0001098 basal transcription machinery binding 2/199 60/18639 0.0333333333333333 3.12211055276382 0.134580124542329 0.389053444755294 GO:0001099 basal RNA polymerase II transcription machinery binding 2/199 60/18639 0.0333333333333333 3.12211055276382 0.134580124542329 0.389053444755294 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/199 60/18639 0.0333333333333333 3.12211055276382 0.134580124542329 0.389053444755294 GO:0015026 coreceptor activity 2/199 61/18639 0.0327868852459016 3.07092841255458 0.138211996483417 0.389053444755294 GO:0019905 syntaxin binding 2/199 61/18639 0.0327868852459016 3.07092841255458 0.138211996483417 0.389053444755294 GO:0005161 platelet-derived growth factor receptor binding 1/199 14/18639 0.0714285714285714 6.69023689877961 0.139574200181195 0.389053444755294 GO:0019992 diacylglycerol binding 1/199 14/18639 0.0714285714285714 6.69023689877961 0.139574200181195 0.389053444755294 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/199 14/18639 0.0714285714285714 6.69023689877961 0.139574200181195 0.389053444755294 GO:0070742 C2H2 zinc finger domain binding 1/199 14/18639 0.0714285714285714 6.69023689877961 0.139574200181195 0.389053444755294 GO:0003713 transcription coactivator activity 5/199 256/18639 0.01953125 1.82936165201005 0.139698727267345 0.389053444755294 GO:0008528 G protein-coupled peptide receptor activity 3/199 122/18639 0.0245901639344262 2.30319630941593 0.142065480828884 0.393528978980546 GO:0004129 cytochrome-c oxidase activity 1/199 15/18639 0.0666666666666667 6.24422110552764 0.148767474498722 0.395187445078656 GO:0004953 icosanoid receptor activity 1/199 15/18639 0.0666666666666667 6.24422110552764 0.148767474498722 0.395187445078656 GO:0005523 tropomyosin binding 1/199 15/18639 0.0666666666666667 6.24422110552764 0.148767474498722 0.395187445078656 GO:0016846 carbon-sulfur lyase activity 1/199 15/18639 0.0666666666666667 6.24422110552764 0.148767474498722 0.395187445078656 GO:0017081 chloride channel regulator activity 1/199 15/18639 0.0666666666666667 6.24422110552764 0.148767474498722 0.395187445078656 GO:0031005 filamin binding 1/199 15/18639 0.0666666666666667 6.24422110552764 0.148767474498722 0.395187445078656 GO:0050780 dopamine receptor binding 1/199 15/18639 0.0666666666666667 6.24422110552764 0.148767474498722 0.395187445078656 GO:0051371 muscle alpha-actinin binding 1/199 15/18639 0.0666666666666667 6.24422110552764 0.148767474498722 0.395187445078656 GO:0140297 DNA-binding transcription factor binding 8/199 488/18639 0.0163934426229508 1.53546420627729 0.152420179884556 0.402824761123469 GO:0042826 histone deacetylase binding 3/199 127/18639 0.0236220472440945 2.21251928936019 0.154596185083698 0.40345937781256 GO:0008235 metalloexopeptidase activity 2/199 66/18639 0.0303030303030303 2.83828232069438 0.15667497270143 0.40345937781256 GO:0001653 peptide receptor activity 3/199 128/18639 0.0234375 2.19523398241206 0.157143187710732 0.40345937781256 GO:0031490 chromatin DNA binding 3/199 128/18639 0.0234375 2.19523398241206 0.157143187710732 0.40345937781256 GO:0005521 lamin binding 1/199 16/18639 0.0625 5.85395728643216 0.15786301104161 0.40345937781256 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/199 16/18639 0.0625 5.85395728643216 0.15786301104161 0.40345937781256 GO:0016500 protein-hormone receptor activity 2/199 67/18639 0.0298507462686567 2.79591989799745 0.16042246295766 0.40345937781256 GO:0050840 extracellular matrix binding 2/199 67/18639 0.0298507462686567 2.79591989799745 0.16042246295766 0.40345937781256 GO:0031072 heat shock protein binding 3/199 131/18639 0.0229007633587786 2.14496144846369 0.164861383275894 0.40345937781256 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/199 17/18639 0.0588235294117647 5.5096068578185 0.166861843711036 0.40345937781256 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/199 17/18639 0.0588235294117647 5.5096068578185 0.166861843711036 0.40345937781256 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/199 17/18639 0.0588235294117647 5.5096068578185 0.166861843711036 0.40345937781256 GO:0019198 transmembrane receptor protein phosphatase activity 1/199 17/18639 0.0588235294117647 5.5096068578185 0.166861843711036 0.40345937781256 GO:0032183 SUMO binding 1/199 17/18639 0.0588235294117647 5.5096068578185 0.166861843711036 0.40345937781256 GO:0032977 membrane insertase activity 1/199 17/18639 0.0588235294117647 5.5096068578185 0.166861843711036 0.40345937781256 GO:0038191 neuropilin binding 1/199 17/18639 0.0588235294117647 5.5096068578185 0.166861843711036 0.40345937781256 GO:0046965 nuclear retinoid X receptor binding 1/199 17/18639 0.0588235294117647 5.5096068578185 0.166861843711036 0.40345937781256 GO:0070492 oligosaccharide binding 1/199 17/18639 0.0588235294117647 5.5096068578185 0.166861843711036 0.40345937781256 GO:0005179 hormone activity 3/199 132/18639 0.0227272727272727 2.12871174052079 0.167459008165445 0.40345937781256 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 6/199 349/18639 0.0171919770773639 1.61025759168335 0.170906605525989 0.409859359548438 GO:1901681 sulfur compound binding 5/199 275/18639 0.0181818181818182 1.70296939241663 0.171843640451326 0.410207399787035 GO:0004970 glutamate-gated receptor activity 1/199 18/18639 0.0555555555555556 5.2035175879397 0.175764995526175 0.411974061912029 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/199 18/18639 0.0555555555555556 5.2035175879397 0.175764995526175 0.411974061912029 GO:0031690 adrenergic receptor binding 1/199 18/18639 0.0555555555555556 5.2035175879397 0.175764995526175 0.411974061912029 GO:0070064 proline-rich region binding 1/199 18/18639 0.0555555555555556 5.2035175879397 0.175764995526175 0.411974061912029 GO:0019838 growth factor binding 3/199 136/18639 0.0220588235294118 2.06610257168194 0.177967319459103 0.415257078737908 GO:0005518 collagen binding 2/199 72/18639 0.0277777777777778 2.60175879396985 0.179391086360949 0.416702164730814 GO:0016922 nuclear receptor binding 3/199 137/18639 0.0218978102189781 2.05102153101273 0.180622610571866 0.41768978694744 GO:0043539 protein serine/threonine kinase activator activity 2/199 73/18639 0.0273972602739726 2.5661182625456 0.183225838942184 0.418813551745499 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/199 19/18639 0.0526315789473684 4.92964824120603 0.184573478738155 0.418813551745499 GO:0030506 ankyrin binding 1/199 19/18639 0.0526315789473684 4.92964824120603 0.184573478738155 0.418813551745499 GO:0042834 peptidoglycan binding 1/199 19/18639 0.0526315789473684 4.92964824120603 0.184573478738155 0.418813551745499 GO:0051015 actin filament binding 4/199 209/18639 0.0191387559808612 1.79259936043856 0.185151164767798 0.418813551745499 GO:0030295 protein kinase activator activity 3/199 139/18639 0.0215827338129496 2.02151042984708 0.185965324464627 0.4188262524899 GO:0035091 phosphatidylinositol binding 5/199 284/18639 0.0176056338028169 1.6490020525161 0.187993024932387 0.420686288993225 GO:0004713 protein tyrosine kinase activity 3/199 140/18639 0.0214285714285714 2.00707106963388 0.188652258112067 0.420686288993225 GO:0042578 phosphoric ester hydrolase activity 6/199 363/18639 0.0165289256198347 1.54815399310603 0.193120311157865 0.420686288993225 GO:0001972 retinoic acid binding 1/199 20/18639 0.05 4.68316582914573 0.193288294942833 0.420686288993225 GO:0016004 phospholipase activator activity 1/199 20/18639 0.05 4.68316582914573 0.193288294942833 0.420686288993225 GO:0016505 peptidase activator activity involved in apoptotic process 1/199 20/18639 0.05 4.68316582914573 0.193288294942833 0.420686288993225 GO:0030742 GTP-dependent protein binding 1/199 20/18639 0.05 4.68316582914573 0.193288294942833 0.420686288993225 GO:0140939 histone H4 methyltransferase activity 1/199 20/18639 0.05 4.68316582914573 0.193288294942833 0.420686288993225 GO:0003724 RNA helicase activity 2/199 77/18639 0.025974025974026 2.43281341773804 0.19867808297211 0.426541639341616 GO:0019903 protein phosphatase binding 3/199 144/18639 0.0208333333333333 1.95131909547739 0.199498176420891 0.426541639341616 GO:0005248 voltage-gated sodium channel activity 1/199 21/18639 0.0476190476190476 4.46015793251974 0.201910435192383 0.426541639341616 GO:0010314 phosphatidylinositol-5-phosphate binding 1/199 21/18639 0.0476190476190476 4.46015793251974 0.201910435192383 0.426541639341616 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/199 21/18639 0.0476190476190476 4.46015793251974 0.201910435192383 0.426541639341616 GO:0051428 peptide hormone receptor binding 1/199 21/18639 0.0476190476190476 4.46015793251974 0.201910435192383 0.426541639341616 GO:1904047 S-adenosyl-L-methionine binding 1/199 21/18639 0.0476190476190476 4.46015793251974 0.201910435192383 0.426541639341616 GO:0019199 transmembrane receptor protein kinase activity 2/199 78/18639 0.0256410256410256 2.40162350212601 0.202566106714358 0.426541639341616 GO:0008186 ATP-dependent activity, acting on RNA 2/199 79/18639 0.0253164556962025 2.37122320463075 0.206462822215584 0.431240894789003 GO:0046332 SMAD binding 2/199 79/18639 0.0253164556962025 2.37122320463075 0.206462822215584 0.431240894789003 GO:0008093 cytoskeletal anchor activity 1/199 22/18639 0.0454545454545455 4.25742348104157 0.210440880105732 0.434397037133419 GO:0008970 phospholipase A1 activity 1/199 22/18639 0.0454545454545455 4.25742348104157 0.210440880105732 0.434397037133419 GO:0019209 kinase activator activity 3/199 148/18639 0.0202702702702703 1.89858074154557 0.210489684016386 0.434397037133419 GO:0004602 glutathione peroxidase activity 1/199 23/18639 0.0434782608695652 4.07231811230063 0.218880599977836 0.442501606886822 GO:0016493 C-C chemokine receptor activity 1/199 23/18639 0.0434782608695652 4.07231811230063 0.218880599977836 0.442501606886822 GO:0016917 GABA receptor activity 1/199 23/18639 0.0434782608695652 4.07231811230063 0.218880599977836 0.442501606886822 GO:0017134 fibroblast growth factor binding 1/199 23/18639 0.0434782608695652 4.07231811230063 0.218880599977836 0.442501606886822 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/199 23/18639 0.0434782608695652 4.07231811230063 0.218880599977836 0.442501606886822 GO:0003774 cytoskeletal motor activity 3/199 153/18639 0.0196078431372549 1.83653561927283 0.22441083529839 0.442501606886822 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/199 24/18639 0.0416666666666667 3.90263819095477 0.227230554887828 0.442501606886822 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/199 24/18639 0.0416666666666667 3.90263819095477 0.227230554887828 0.442501606886822 GO:0004622 lysophospholipase activity 1/199 24/18639 0.0416666666666667 3.90263819095477 0.227230554887828 0.442501606886822 GO:0004806 triacylglycerol lipase activity 1/199 24/18639 0.0416666666666667 3.90263819095477 0.227230554887828 0.442501606886822 GO:0005540 hyaluronic acid binding 1/199 24/18639 0.0416666666666667 3.90263819095477 0.227230554887828 0.442501606886822 GO:0019957 C-C chemokine binding 1/199 24/18639 0.0416666666666667 3.90263819095477 0.227230554887828 0.442501606886822 GO:0060229 lipase activator activity 1/199 24/18639 0.0416666666666667 3.90263819095477 0.227230554887828 0.442501606886822 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/199 24/18639 0.0416666666666667 3.90263819095477 0.227230554887828 0.442501606886822 GO:0070840 dynein complex binding 1/199 24/18639 0.0416666666666667 3.90263819095477 0.227230554887828 0.442501606886822 GO:0000287 magnesium ion binding 4/199 230/18639 0.0173913043478261 1.62892724492025 0.231616552527487 0.444431158889165 GO:0140375 immune receptor activity 3/199 156/18639 0.0192307692307692 1.80121762659451 0.232849406141099 0.444431158889165 GO:0003707 nuclear steroid receptor activity 1/199 25/18639 0.04 3.74653266331658 0.235491694806029 0.444431158889165 GO:0017025 TBP-class protein binding 1/199 25/18639 0.04 3.74653266331658 0.235491694806029 0.444431158889165 GO:0017056 structural constituent of nuclear pore 1/199 25/18639 0.04 3.74653266331658 0.235491694806029 0.444431158889165 GO:0019211 phosphatase activator activity 1/199 25/18639 0.04 3.74653266331658 0.235491694806029 0.444431158889165 GO:0042974 nuclear retinoic acid receptor binding 1/199 25/18639 0.04 3.74653266331658 0.235491694806029 0.444431158889165 GO:0001637 G protein-coupled chemoattractant receptor activity 1/199 26/18639 0.0384615384615385 3.60243525318902 0.243664959699851 0.444431158889165 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/199 26/18639 0.0384615384615385 3.60243525318902 0.243664959699851 0.444431158889165 GO:0004950 chemokine receptor activity 1/199 26/18639 0.0384615384615385 3.60243525318902 0.243664959699851 0.444431158889165 GO:0005112 Notch binding 1/199 26/18639 0.0384615384615385 3.60243525318902 0.243664959699851 0.444431158889165 GO:0005160 transforming growth factor beta receptor binding 1/199 26/18639 0.0384615384615385 3.60243525318902 0.243664959699851 0.444431158889165 GO:0008066 glutamate receptor activity 1/199 26/18639 0.0384615384615385 3.60243525318902 0.243664959699851 0.444431158889165 GO:0030247 polysaccharide binding 1/199 26/18639 0.0384615384615385 3.60243525318902 0.243664959699851 0.444431158889165 GO:0030507 spectrin binding 1/199 26/18639 0.0384615384615385 3.60243525318902 0.243664959699851 0.444431158889165 GO:0034237 protein kinase A regulatory subunit binding 1/199 26/18639 0.0384615384615385 3.60243525318902 0.243664959699851 0.444431158889165 GO:0043548 phosphatidylinositol 3-kinase binding 1/199 26/18639 0.0384615384615385 3.60243525318902 0.243664959699851 0.444431158889165 GO:0070006 metalloaminopeptidase activity 1/199 26/18639 0.0384615384615385 3.60243525318902 0.243664959699851 0.444431158889165 GO:0004364 glutathione transferase activity 1/199 27/18639 0.037037037037037 3.46901172529313 0.251751279638589 0.455969100883878 GO:0035255 ionotropic glutamate receptor binding 1/199 27/18639 0.037037037037037 3.46901172529313 0.251751279638589 0.455969100883878 GO:0072341 modified amino acid binding 2/199 91/18639 0.021978021978022 2.05853443039373 0.253685824525554 0.45787197597295 GO:0015081 sodium ion transmembrane transporter activity 3/199 164/18639 0.0182926829268293 1.71335335212649 0.255614717683467 0.459219507838608 GO:0046875 ephrin receptor binding 1/199 28/18639 0.0357142857142857 3.34511844938981 0.259751574897128 0.459219507838608 GO:0046966 nuclear thyroid hormone receptor binding 1/199 28/18639 0.0357142857142857 3.34511844938981 0.259751574897128 0.459219507838608 GO:0051019 mitogen-activated protein kinase binding 1/199 28/18639 0.0357142857142857 3.34511844938981 0.259751574897128 0.459219507838608 GO:0051393 alpha-actinin binding 1/199 28/18639 0.0357142857142857 3.34511844938981 0.259751574897128 0.459219507838608 GO:0097718 disordered domain specific binding 1/199 28/18639 0.0357142857142857 3.34511844938981 0.259751574897128 0.459219507838608 GO:0004175 endopeptidase activity 6/199 405/18639 0.0148148148148148 1.38760469011725 0.265447774772958 0.463716988756975 GO:0005201 extracellular matrix structural constituent 3/199 168/18639 0.0178571428571429 1.6725592246949 0.267114619277 0.463716988756975 GO:0003785 actin monomer binding 1/199 29/18639 0.0344827586206897 3.22976953734188 0.267666756058563 0.463716988756975 GO:0004181 metallocarboxypeptidase activity 1/199 29/18639 0.0344827586206897 3.22976953734188 0.267666756058563 0.463716988756975 GO:0043236 laminin binding 1/199 29/18639 0.0344827586206897 3.22976953734188 0.267666756058563 0.463716988756975 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/199 29/18639 0.0344827586206897 3.22976953734188 0.267666756058563 0.463716988756975 GO:0004867 serine-type endopeptidase inhibitor activity 2/199 95/18639 0.0210526315789474 1.97185929648241 0.269518396220739 0.465368430807809 GO:0033218 amide binding 4/199 247/18639 0.0161943319838057 1.51681484344801 0.2711111563404 0.466563385329991 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/199 30/18639 0.0333333333333333 3.12211055276382 0.275497724115755 0.470982907894261 GO:0033612 receptor serine/threonine kinase binding 1/199 30/18639 0.0333333333333333 3.12211055276382 0.275497724115755 0.470982907894261 GO:0004725 protein tyrosine phosphatase activity 2/199 98/18639 0.0204081632653061 1.91149625679417 0.281390407257106 0.4748255726738 GO:0005249 voltage-gated potassium channel activity 2/199 98/18639 0.0204081632653061 1.91149625679417 0.281390407257106 0.4748255726738 GO:0005452 solute:inorganic anion antiporter activity 1/199 31/18639 0.032258064516129 3.02139730912628 0.283245370571823 0.4748255726738 GO:0017147 Wnt-protein binding 1/199 31/18639 0.032258064516129 3.02139730912628 0.283245370571823 0.4748255726738 GO:0070273 phosphatidylinositol-4-phosphate binding 1/199 31/18639 0.032258064516129 3.02139730912628 0.283245370571823 0.4748255726738 GO:0072349 modified amino acid transmembrane transporter activity 1/199 31/18639 0.032258064516129 3.02139730912628 0.283245370571823 0.4748255726738 GO:0015106 bicarbonate transmembrane transporter activity 1/199 32/18639 0.03125 2.92697864321608 0.29091057753959 0.482986151171498 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/199 32/18639 0.03125 2.92697864321608 0.29091057753959 0.482986151171498 GO:0043425 bHLH transcription factor binding 1/199 32/18639 0.03125 2.92697864321608 0.29091057753959 0.482986151171498 GO:0019956 chemokine binding 1/199 33/18639 0.0303030303030303 2.83828232069438 0.298494217839994 0.490857158225768 GO:0071889 14-3-3 protein binding 1/199 33/18639 0.0303030303030303 2.83828232069438 0.298494217839994 0.490857158225768 GO:0140416 transcription regulator inhibitor activity 1/199 33/18639 0.0303030303030303 2.83828232069438 0.298494217839994 0.490857158225768 GO:0030332 cyclin binding 1/199 34/18639 0.0294117647058824 2.75480342890925 0.305997155099472 0.501602931460527 GO:0000149 SNARE binding 2/199 106/18639 0.0188679245283019 1.76723238835688 0.312945989308908 0.508939455524753 GO:0005154 epidermal growth factor receptor binding 1/199 35/18639 0.0285714285714286 2.67609475951184 0.313420243846325 0.508939455524753 GO:0016229 steroid dehydrogenase activity 1/199 35/18639 0.0285714285714286 2.67609475951184 0.313420243846325 0.508939455524753 GO:0019888 protein phosphatase regulator activity 2/199 107/18639 0.0186915887850467 1.75071619781149 0.31687292259093 0.512938043444068 GO:0004033 aldo-keto reductase (NADPH) activity 1/199 36/18639 0.0277777777777778 2.60175879396985 0.320764329606085 0.516012182409789 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/199 36/18639 0.0277777777777778 2.60175879396985 0.320764329606085 0.516012182409789 GO:0031406 carboxylic acid binding 3/199 187/18639 0.0160427807486631 1.50262005213232 0.322350247935314 0.516957982756944 GO:0140597 protein carrier chaperone 3/199 188/18639 0.0159574468085106 1.49462739228055 0.325270274794342 0.519885627084025 GO:0141003 histone H2AX kinase activity 5/199 354/18639 0.0141242937853107 1.32292820032365 0.327500152242996 0.519885627084025 GO:0042805 actinin binding 1/199 37/18639 0.027027027027027 2.53144098872742 0.328030248995882 0.519885627084025 GO:0043177 organic acid binding 3/199 189/18639 0.0158730158730159 1.48671931083991 0.328190347599375 0.519885627084025 GO:0019902 phosphatase binding 3/199 190/18639 0.0157894736842105 1.47889447236181 0.331110298528407 0.522911995846691 GO:0140996 histone H3 kinase activity 5/199 357/18639 0.0140056022408964 1.31181115662345 0.333813203472992 0.523022150137453 GO:0005501 retinoid binding 1/199 38/18639 0.0263157894736842 2.46482412060302 0.335218829817827 0.523022150137453 GO:0019840 isoprenoid binding 1/199 38/18639 0.0263157894736842 2.46482412060302 0.335218829817827 0.523022150137453 GO:0043531 ADP binding 1/199 38/18639 0.0263157894736842 2.46482412060302 0.335218829817827 0.523022150137453 GO:0005200 structural constituent of cytoskeleton 2/199 112/18639 0.0178571428571429 1.6725592246949 0.336424574543625 0.52332711595675 GO:0035173 histone kinase activity 5/199 360/18639 0.0138888888888889 1.30087939698492 0.340137620779275 0.527518825040911 GO:0005216 monoatomic ion channel activity 6/199 448/18639 0.0133928571428571 1.25441941852118 0.345336207660046 0.533841392638703 GO:0001221 transcription coregulator binding 2/199 115/18639 0.0173913043478261 1.62892724492025 0.34807767513172 0.533841392638703 GO:0061791 GTPase motor activity 1/199 40/18639 0.025 2.34158291457286 0.34936724344502 0.533841392638703 GO:0071855 neuropeptide receptor binding 1/199 40/18639 0.025 2.34158291457286 0.34936724344502 0.533841392638703 GO:1990606 membrane scission GTPase motor activity 1/199 40/18639 0.025 2.34158291457286 0.34936724344502 0.533841392638703 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/199 41/18639 0.024390243902439 2.28447113616865 0.356328688606289 0.542877237347228 GO:0042056 chemoattractant activity 1/199 42/18639 0.0238095238095238 2.23007896625987 0.36321602009179 0.551747502661428 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/199 43/18639 0.0232558139534884 2.17821666471894 0.370030022995577 0.560454830151196 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/199 122/18639 0.0163934426229508 1.53546420627729 0.374990291912348 0.566311869418648 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/199 44/18639 0.0227272727272727 2.12871174052079 0.376771474136891 0.567347743031715 GO:0005267 potassium channel activity 2/199 124/18639 0.0161290322580645 1.51069865456314 0.382598729802485 0.572399168968623 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/199 45/18639 0.0222222222222222 2.08140703517588 0.383441142146935 0.572399168968623 GO:0051539 4 iron, 4 sulfur cluster binding 1/199 45/18639 0.0222222222222222 2.08140703517588 0.383441142146935 0.572399168968623 GO:0004180 carboxypeptidase activity 1/199 46/18639 0.0217391304347826 2.03615905615032 0.390039787554741 0.580576465383207 GO:0032266 phosphatidylinositol-3-phosphate binding 1/199 48/18639 0.0208333333333333 1.95131909547739 0.403027012677898 0.59818909045029 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/199 130/18639 0.0153846153846154 1.44097410127561 0.405180387724292 0.599666973831952 GO:0001222 transcription corepressor binding 1/199 49/18639 0.0204081632653061 1.91149625679417 0.409417073700818 0.602494443684727 GO:0035254 glutamate receptor binding 1/199 49/18639 0.0204081632653061 1.91149625679417 0.409417073700818 0.602494443684727 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/199 132/18639 0.0151515151515152 1.41914116034719 0.412620836925279 0.605488933505084 GO:0016830 carbon-carbon lyase activity 1/199 51/18639 0.0196078431372549 1.83653561927283 0.421993737557228 0.617493661171311 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/199 52/18639 0.0192307692307692 1.80121762659451 0.428181775335693 0.624783548236307 GO:0004864 protein phosphatase inhibitor activity 1/199 53/18639 0.0188679245283019 1.76723238835688 0.434303894381703 0.627482408705375 GO:0005246 calcium channel regulator activity 1/199 53/18639 0.0188679245283019 1.76723238835688 0.434303894381703 0.627482408705375 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/199 53/18639 0.0188679245283019 1.76723238835688 0.434303894381703 0.627482408705375 GO:0061134 peptidase regulator activity 3/199 226/18639 0.0132743362831858 1.2433183617201 0.43487680448886 0.627482408705375 GO:0070851 growth factor receptor binding 2/199 139/18639 0.0143884892086331 1.34767361989805 0.438291580696277 0.630652885557421 GO:0140463 chromatin-protein adaptor activity 1/199 54/18639 0.0185185185185185 1.73450586264657 0.440360793392682 0.631875044258751 GO:0022836 gated channel activity 4/199 318/18639 0.0125786163522013 1.17815492557125 0.441769098226515 0.632144731716394 GO:0005085 guanyl-nucleotide exchange factor activity 3/199 230/18639 0.0130434782608696 1.22169543369019 0.446099258519683 0.63658241298401 GO:0020037 heme binding 2/199 142/18639 0.0140845070422535 1.31920164201288 0.449106992534793 0.639113797068744 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/199 56/18639 0.0178571428571429 1.6725592246949 0.452281689333747 0.640687034557065 GO:0022843 voltage-gated monoatomic cation channel activity 2/199 143/18639 0.013986013986014 1.3099764557051 0.452686205883949 0.640687034557065 GO:0019955 cytokine binding 2/199 144/18639 0.0138888888888889 1.30087939698492 0.456252234467936 0.643144093253137 GO:0004601 peroxidase activity 1/199 57/18639 0.0175438596491228 1.64321608040201 0.458147047124339 0.643144093253137 GO:0016504 peptidase activator activity 1/199 57/18639 0.0175438596491228 1.64321608040201 0.458147047124339 0.643144093253137 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/199 58/18639 0.0172413793103448 1.61488476867094 0.463949906753134 0.649529869454387 GO:0001786 phosphatidylserine binding 1/199 59/18639 0.0169491525423729 1.58751384038838 0.469690930839896 0.650534497794294 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/199 59/18639 0.0169491525423729 1.58751384038838 0.469690930839896 0.650534497794294 GO:0036002 pre-mRNA binding 1/199 59/18639 0.0169491525423729 1.58751384038838 0.469690930839896 0.650534497794294 GO:0070063 RNA polymerase binding 1/199 59/18639 0.0169491525423729 1.58751384038838 0.469690930839896 0.650534497794294 GO:0000510 H3-H4 histone complex chaperone activity 2/199 151/18639 0.0132450331125828 1.24057372957503 0.48083509082165 0.65670928457246 GO:0140584 chromatin extrusion motor activity 2/199 151/18639 0.0132450331125828 1.24057372957503 0.48083509082165 0.65670928457246 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/199 151/18639 0.0132450331125828 1.24057372957503 0.48083509082165 0.65670928457246 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/199 151/18639 0.0132450331125828 1.24057372957503 0.48083509082165 0.65670928457246 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/199 61/18639 0.0163934426229508 1.53546420627729 0.480990087989948 0.65670928457246 GO:0015616 DNA translocase activity 2/199 152/18639 0.0131578947368421 1.23241206030151 0.484291402908648 0.65670928457246 GO:0046906 tetrapyrrole binding 2/199 152/18639 0.0131578947368421 1.23241206030151 0.484291402908648 0.65670928457246 GO:0140674 ATP-dependent histone chaperone activity 2/199 152/18639 0.0131578947368421 1.23241206030151 0.484291402908648 0.65670928457246 GO:0061775 cohesin loader activity 2/199 153/18639 0.0130718954248366 1.22435707951522 0.487733529631963 0.659650047909548 GO:0022824 transmitter-gated monoatomic ion channel activity 1/199 63/18639 0.0158730158730159 1.48671931083991 0.492049681048615 0.662030479956318 GO:0022835 transmitter-gated channel activity 1/199 63/18639 0.0158730158730159 1.48671931083991 0.492049681048615 0.662030479956318 GO:0004386 helicase activity 2/199 155/18639 0.0129032258064516 1.20855892365051 0.494574861943127 0.663041472874195 GO:0005261 monoatomic cation channel activity 4/199 341/18639 0.0117302052785924 1.09868993059137 0.495361100390567 0.663041472874195 GO:0140104 molecular carrier activity 3/199 249/18639 0.0120481927710843 1.12847369377006 0.498104540903509 0.664995237597983 GO:0140658 ATP-dependent chromatin remodeler activity 2/199 158/18639 0.0126582278481013 1.18561160231537 0.504728280674444 0.672106039561343 GO:0003689 DNA clamp loader activity 2/199 160/18639 0.0125 1.17079145728643 0.511423925992884 0.677538602722031 GO:0015079 potassium ion transmembrane transporter activity 2/199 160/18639 0.0125 1.17079145728643 0.511423925992884 0.677538602722031 GO:0042054 histone methyltransferase activity 1/199 67/18639 0.0149253731343284 1.39795994899873 0.513470285248811 0.678473952547367 GO:0004866 endopeptidase inhibitor activity 2/199 161/18639 0.0124223602484472 1.16351946065732 0.514749543148871 0.678473952547367 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/199 68/18639 0.0147058823529412 1.37740171445463 0.518683477863256 0.681923963282149 GO:0002039 p53 binding 1/199 69/18639 0.0144927536231884 1.35743937076688 0.523841088541476 0.682818744780834 GO:0016279 protein-lysine N-methyltransferase activity 1/199 69/18639 0.0144927536231884 1.35743937076688 0.523841088541476 0.682818744780834 GO:0098960 postsynaptic neurotransmitter receptor activity 1/199 69/18639 0.0144927536231884 1.35743937076688 0.523841088541476 0.682818744780834 GO:0140713 histone chaperone activity 2/199 164/18639 0.0121951219512195 1.14223556808432 0.524636796182957 0.682818744780834 GO:0046873 metal ion transmembrane transporter activity 5/199 450/18639 0.0111111111111111 1.04070351758794 0.527110610432736 0.684319038105657 GO:0016278 lysine N-methyltransferase activity 1/199 70/18639 0.0142857142857143 1.33804737975592 0.528943706924903 0.68498210046775 GO:0140299 molecular sensor activity 1/199 71/18639 0.0140845070422535 1.31920164201288 0.533991916431174 0.68979504416795 GO:0030414 peptidase inhibitor activity 2/199 169/18639 0.0118343195266272 1.10844161636585 0.540813500416577 0.696869137352704 GO:0004521 RNA endonuclease activity 1/199 73/18639 0.0136986301369863 1.2830591312728 0.543927411755283 0.697411879428803 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/199 73/18639 0.0136986301369863 1.2830591312728 0.543927411755283 0.697411879428803 GO:0008514 organic anion transmembrane transporter activity 3/199 269/18639 0.0111524163568773 1.04457230389868 0.55008997240474 0.701202440293509 GO:0008201 heparin binding 2/199 172/18639 0.0116279069767442 1.08910833235947 0.550336180679643 0.701202440293509 GO:0005244 voltage-gated monoatomic ion channel activity 2/199 173/18639 0.0115606936416185 1.082812908473 0.553479610895499 0.701202440293509 GO:0003725 double-stranded RNA binding 1/199 75/18639 0.0133333333333333 1.24884422110553 0.553652119845647 0.701202440293509 GO:0019003 GDP binding 1/199 75/18639 0.0133333333333333 1.24884422110553 0.553652119845647 0.701202440293509 GO:0017022 myosin binding 1/199 76/18639 0.0131578947368421 1.23241206030151 0.558436822934998 0.702021794126204 GO:0051536 iron-sulfur cluster binding 1/199 76/18639 0.0131578947368421 1.23241206030151 0.558436822934998 0.702021794126204 GO:0004721 phosphoprotein phosphatase activity 2/199 175/18639 0.0114285714285714 1.07043790380474 0.559720079100622 0.702021794126204 GO:0022832 voltage-gated channel activity 2/199 175/18639 0.0114285714285714 1.07043790380474 0.559720079100622 0.702021794126204 GO:0004252 serine-type endopeptidase activity 2/199 176/18639 0.0113636363636364 1.06435587026039 0.562817059794603 0.702945335212612 GO:0051540 metal cluster binding 1/199 77/18639 0.012987012987013 1.21640670886902 0.563170490566089 0.702945335212612 GO:0043021 ribonucleoprotein complex binding 2/199 177/18639 0.0112994350282486 1.05834256025892 0.565898503945206 0.704652464047155 GO:0015370 solute:sodium symporter activity 1/199 79/18639 0.0126582278481013 1.18561160231537 0.57248688030756 0.709445464113196 GO:0033293 monocarboxylic acid binding 1/199 79/18639 0.0126582278481013 1.18561160231537 0.57248688030756 0.709445464113196 GO:0048306 calcium-dependent protein binding 1/199 80/18639 0.0125 1.17079145728643 0.577070668605986 0.712012188991957 GO:0030246 carbohydrate binding 3/199 280/18639 0.0107142857142857 1.00353553481694 0.577307180263749 0.712012188991957 GO:0001618 virus receptor activity 1/199 81/18639 0.0123456790123457 1.15633724176438 0.581605553941802 0.715609683947396 GO:0140272 exogenous protein binding 1/199 82/18639 0.0121951219512195 1.14223556808432 0.586092055437954 0.718871276143355 GO:0061135 endopeptidase regulator activity 2/199 184/18639 0.0108695652173913 1.01807952807516 0.587031949437527 0.718871276143355 GO:0001540 amyloid-beta binding 1/199 83/18639 0.0120481927710843 1.12847369377006 0.590530686734384 0.719752695831555 GO:0030165 PDZ domain binding 1/199 83/18639 0.0120481927710843 1.12847369377006 0.590530686734384 0.719752695831555 GO:0004527 exonuclease activity 1/199 84/18639 0.0119047619047619 1.11503948312994 0.59492195604565 0.721708602416034 GO:0051117 ATPase binding 1/199 84/18639 0.0119047619047619 1.11503948312994 0.59492195604565 0.721708602416034 GO:0046943 carboxylic acid transmembrane transporter activity 2/199 188/18639 0.0106382978723404 0.996418261520368 0.598763997259614 0.724672314440374 GO:0005342 organic acid transmembrane transporter activity 2/199 189/18639 0.0105820105820106 0.991146207226609 0.601657833084857 0.726477290298266 GO:0016209 antioxidant activity 1/199 86/18639 0.0116279069767442 1.08910833235947 0.603564414785511 0.727084574090452 GO:0003712 transcription coregulator activity 5/199 495/18639 0.0101010101010101 0.946094106898127 0.611976417899372 0.7337562736188 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/199 88/18639 0.0113636363636364 1.06435587026039 0.612023391018109 0.7337562736188 GO:0008236 serine-type peptidase activity 2/199 194/18639 0.0103092783505155 0.965601201885717 0.61589204016357 0.7337562736188 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/199 89/18639 0.0112359550561798 1.05239681553837 0.616185287691464 0.7337562736188 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/199 89/18639 0.0112359550561798 1.05239681553837 0.616185287691464 0.7337562736188 GO:0140793 histone H2AXY142 phosphatase activity 1/199 90/18639 0.0111111111111111 1.04070351758794 0.620302760885501 0.736965206740114 GO:0017171 serine hydrolase activity 2/199 198/18639 0.0101010101010101 0.946094106898127 0.626997896395562 0.741680772674616 GO:0043178 alcohol binding 1/199 92/18639 0.0108695652173913 1.01807952807516 0.628406319051587 0.741680772674616 GO:0031625 ubiquitin protein ligase binding 3/199 302/18639 0.00993377483443709 0.930430297181271 0.628567295760919 0.741680772674616 GO:0008276 protein methyltransferase activity 1/199 95/18639 0.0105263157894737 0.985929648241206 0.640240114280574 0.753737225448494 GO:0030594 neurotransmitter receptor activity 1/199 97/18639 0.0103092783505155 0.965601201885717 0.64792022542902 0.761049153678531 GO:0008170 N-methyltransferase activity 1/199 98/18639 0.0102040816326531 0.955748128397087 0.651698883348318 0.763755704919522 GO:0004518 nuclease activity 2/199 209/18639 0.00956937799043062 0.896299680219278 0.656257322587369 0.767361835440761 GO:0008094 ATP-dependent activity, acting on DNA 2/199 210/18639 0.00952380952380952 0.892031586503948 0.658824787308116 0.768628918526135 GO:0015171 amino acid transmembrane transporter activity 1/199 102/18639 0.00980392156862745 0.918267809636417 0.666414255898311 0.775736145068146 GO:0044389 ubiquitin-like protein ligase binding 3/199 322/18639 0.0093167701863354 0.872639595492993 0.671340469995121 0.778081641450597 GO:0016741 transferase activity, transferring one-carbon groups 2/199 215/18639 0.00930232558139535 0.871286665887577 0.671433385576095 0.778081641450597 GO:0004843 cysteine-type deubiquitinase activity 1/199 108/18639 0.00925925925925926 0.867252931323283 0.687335352502422 0.792961497987203 GO:0005496 steroid binding 1/199 108/18639 0.00925925925925926 0.867252931323283 0.687335352502422 0.792961497987203 GO:0043022 ribosome binding 1/199 112/18639 0.00892857142857143 0.836279612347452 0.700552134003252 0.802763537810604 GO:0101005 deubiquitinase activity 1/199 115/18639 0.00869565217391304 0.814463622460127 0.710098553164541 0.802763537810604 GO:0009055 electron transfer activity 1/199 116/18639 0.00862068965517241 0.80744238433547 0.713212912261942 0.802763537810604 GO:0015294 solute:monoatomic cation symporter activity 1/199 116/18639 0.00862068965517241 0.80744238433547 0.713212912261942 0.802763537810604 GO:0022853 active monoatomic ion transmembrane transporter activity 1/199 118/18639 0.00847457627118644 0.793756920194191 0.719342112522956 0.802763537810604 GO:0032182 ubiquitin-like protein binding 1/199 120/18639 0.00833333333333333 0.780527638190955 0.725340964040273 0.802763537810604 GO:0004540 RNA nuclease activity 1/199 121/18639 0.00826446280991736 0.774076996553013 0.728292373304056 0.802763537810604 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 2/199 243/18639 0.00823045267489712 0.770891494509585 0.735206433099312 0.802763537810604 GO:0004676 3-phosphoinositide-dependent protein kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0004711 ribosomal protein S6 kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0035175 histone H3S10 kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0035979 histone H2AXS139 kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0044022 histone H3S28 kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0044023 histone H4S1 kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0044024 histone H2AS1 kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0044025 histone H2BS14 kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0072354 histone H3T3 kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0072371 histone H2AS121 kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0072518 Rho-dependent protein serine/threonine kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0140823 histone H2BS36 kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0140855 histone H3S57 kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0140995 histone H2A kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0140997 histone H4 kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0140998 histone H2B kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:1990244 histone H2AT120 kinase activity 2/199 245/18639 0.00816326530612245 0.76459850271767 0.739334188895586 0.802763537810604 GO:0004677 DNA-dependent protein kinase activity 2/199 246/18639 0.00813008130081301 0.761490378722883 0.741377503192002 0.802763537810604 GO:0140857 histone H3T45 kinase activity 2/199 246/18639 0.00813008130081301 0.761490378722883 0.741377503192002 0.802763537810604 GO:0035402 histone H3T11 kinase activity 2/199 247/18639 0.00809716599190283 0.758407421724005 0.743407183104977 0.802763537810604 GO:0035403 histone H3T6 kinase activity 2/199 247/18639 0.00809716599190283 0.758407421724005 0.743407183104977 0.802763537810604 GO:0004519 endonuclease activity 1/199 127/18639 0.0078740157480315 0.737506429786729 0.745349751615264 0.802763537810604 GO:0019783 ubiquitin-like protein peptidase activity 1/199 127/18639 0.0078740157480315 0.737506429786729 0.745349751615264 0.802763537810604 GO:0004679 AMP-activated protein kinase activity 2/199 248/18639 0.00806451612903226 0.755349327281569 0.745423285109847 0.802763537810604 GO:0005262 calcium channel activity 1/199 131/18639 0.00763358778625954 0.714987149487897 0.756125052152749 0.812599122438016 GO:0015297 antiporter activity 1/199 135/18639 0.00740740740740741 0.693802345058626 0.766446599745831 0.819589335185894 GO:0002020 protease binding 1/199 136/18639 0.00735294117647059 0.688700857227313 0.768958333784449 0.819589335185894 GO:0044325 transmembrane transporter binding 1/199 136/18639 0.00735294117647059 0.688700857227313 0.768958333784449 0.819589335185894 GO:0140789 histone phosphatase activity 1/199 136/18639 0.00735294117647059 0.688700857227313 0.768958333784449 0.819589335185894 GO:0140098 catalytic activity, acting on RNA 3/199 387/18639 0.00775193798449612 0.726072221572981 0.785197683695656 0.835179466436037 GO:0016791 phosphatase activity 2/199 273/18639 0.00732600732600733 0.686178143464576 0.791584154706092 0.838653375731157 GO:0015293 symporter activity 1/199 146/18639 0.00684931506849315 0.641529565636401 0.792643619391186 0.838653375731157 GO:0015085 calcium ion transmembrane transporter activity 1/199 147/18639 0.00680272108843537 0.637165418931392 0.794874945825034 0.838653375731157 GO:0005126 cytokine receptor binding 2/199 275/18639 0.00727272727272727 0.681187756966651 0.794939782787641 0.838653375731157 GO:0008509 monoatomic anion transmembrane transporter activity 1/199 149/18639 0.00671140939597315 0.628612862972581 0.799266178564521 0.841503822147199 GO:0015291 secondary active transmembrane transporter activity 2/199 287/18639 0.00696864111498258 0.652706038905328 0.814091434244026 0.855373961335508 GO:0015103 inorganic anion transmembrane transporter activity 1/199 165/18639 0.00606060606060606 0.567656464138876 0.831189876550879 0.870080739828246 GO:0015399 primary active transmembrane transporter activity 1/199 166/18639 0.00602409638554217 0.564236846885028 0.833008281583161 0.870080739828246 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/199 167/18639 0.00598802395209581 0.560858183131225 0.834807196321696 0.870080739828246 GO:0016874 ligase activity 1/199 167/18639 0.00598802395209581 0.560858183131225 0.834807196321696 0.870080739828246 GO:0004674 protein serine/threonine kinase activity 3/199 433/18639 0.0069284064665127 0.648937528288092 0.844468980853863 0.877384949060949 GO:0140030 modification-dependent protein binding 1/199 173/18639 0.00578034682080925 0.5414064542365 0.845202875639795 0.877384949060949 GO:0016853 isomerase activity 1/199 180/18639 0.00555555555555556 0.52035175879397 0.856511105451932 0.887345505248202 GO:0015078 proton transmembrane transporter activity 1/199 185/18639 0.00540540540540541 0.506288197745484 0.864081447037489 0.891771483611317 GO:0015276 ligand-gated monoatomic ion channel activity 1/199 186/18639 0.00537634408602151 0.503566218187713 0.865547134261914 0.891771483611317 GO:0008234 cysteine-type peptidase activity 1/199 187/18639 0.0053475935828877 0.500873350710773 0.866997094717226 0.891771483611317 GO:0022834 ligand-gated channel activity 1/199 188/18639 0.00531914893617021 0.498209130760184 0.868431496307909 0.891771483611317 GO:0022804 active transmembrane transporter activity 3/199 457/18639 0.00656455142231947 0.614857658093531 0.8693911181925 0.891771483611317 GO:0140097 catalytic activity, acting on DNA 2/199 336/18639 0.00595238095238095 0.557519741564968 0.87674378420675 0.897536126915211 GO:0008168 methyltransferase activity 1/199 204/18639 0.00490196078431373 0.459133904818209 0.889396226902843 0.908692791983575 GO:0106310 protein serine kinase activity 2/199 361/18639 0.00554016620498615 0.518910341179582 0.900636219012812 0.918365278442198 GO:0015631 tubulin binding 2/199 385/18639 0.00519480519480519 0.486562683547608 0.919462934568287 0.935720628892677 GO:0042393 histone binding 1/199 247/18639 0.00404858299595142 0.379203710862002 0.930680658224003 0.944942131262554 GO:0042277 peptide binding 1/199 249/18639 0.00401606425702811 0.376157897923352 0.932172643002249 0.944942131262554 GO:0016887 ATP hydrolysis activity 2/199 417/18639 0.00479616306954436 0.449224539966017 0.939405563687907 0.950294090406462 GO:0003730 mRNA 3'-UTR binding 1/199 262/18639 0.00381679389312977 0.357493574743949 0.941121367526091 0.950294090406462 GO:0008017 microtubule binding 1/199 276/18639 0.0036231884057971 0.339359842691719 0.949448396892515 0.956837100370278 GO:0031267 small GTPase binding 1/199 283/18639 0.00353356890459364 0.330965782978497 0.953161335556558 0.958713731686014 GO:0051020 GTPase binding 1/199 315/18639 0.00317460317460317 0.297343862167983 0.966963870178178 0.970711792155613 GO:0045182 translation regulator activity 1/199 356/18639 0.00280898876404494 0.263099203884592 0.978897083258311 0.980790501214324 GO:0016755 aminoacyltransferase activity 1/199 496/18639 0.00201612903225806 0.188837331820392 0.995467148272084 0.995467148272084