ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 88/1840 175/18639 0.502857142857143 5.09388819875776 2.66743868172603e-42 3.28628445588647e-39 GO:0019843 rRNA binding 31/1840 65/18639 0.476923076923077 4.83117892976589 6.29164521652546e-15 3.87565345337969e-12 GO:0051082 unfolded protein binding 43/1840 121/18639 0.355371900826446 3.59987872799138 1.901501380347e-14 7.80883233529166e-12 GO:0044183 protein folding chaperone 29/1840 75/18639 0.386666666666667 3.91689130434783 3.07616107655157e-11 9.47457611577883e-09 GO:0008135 translation factor activity, RNA binding 30/1840 83/18639 0.36144578313253 3.66140649554741 1.02134397302239e-10 2.51659154952716e-08 GO:0140662 ATP-dependent protein folding chaperone 20/1840 40/18639 0.5 5.06494565217391 1.37915672472203e-10 2.53409062074795e-08 GO:0180051 translation factor activity 30/1840 84/18639 0.357142857142857 3.61781832298137 1.43982421633406e-10 2.53409062074795e-08 GO:0009055 electron transfer activity 35/1840 116/18639 0.301724137931034 3.05643272113943 8.92058574570423e-10 1.37377020483845e-07 GO:0048027 mRNA 5'-UTR binding 14/1840 24/18639 0.583333333333333 5.90910326086957 6.00757807345973e-09 8.22370687389154e-07 GO:0015078 proton transmembrane transporter activity 44/1840 185/18639 0.237837837837838 2.4092714453584 2.47658975725725e-08 3.05115858094093e-06 GO:0031072 heat shock protein binding 35/1840 131/18639 0.267175572519084 2.70645950879522 2.96724051031452e-08 3.32330937155227e-06 GO:0140104 molecular carrier activity 53/1840 249/18639 0.21285140562249 2.15616160293347 5.49499676689031e-08 5.64153001400738e-06 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 23/1840 68/18639 0.338235294117647 3.42628676470588 6.43594247394414e-08 6.09929317530706e-06 GO:0140098 catalytic activity, acting on RNA 70/1840 387/18639 0.180878552971576 1.83228008088979 4.17695903364625e-07 3.6757239496087e-05 GO:0043021 ribonucleoprotein complex binding 40/1840 177/18639 0.225988700564972 2.28924097273397 4.48755025729475e-07 3.68577461132475e-05 GO:0042605 peptide antigen binding 17/1840 45/18639 0.377777777777778 3.82684782608696 5.53987485040243e-07 4.26570363480987e-05 GO:0022853 active monoatomic ion transmembrane transporter activity 30/1840 118/18639 0.254237288135593 2.57539609432572 8.9801400415727e-07 6.50796031248092e-05 GO:0003697 single-stranded DNA binding 30/1840 121/18639 0.247933884297521 2.51154329859863 1.58666451453045e-06 0.000108598371216751 GO:0003746 translation elongation factor activity 10/1840 18/18639 0.555555555555556 5.62771739130435 1.7838201623732e-06 0.000115666654739146 GO:0016853 isomerase activity 39/1840 180/18639 0.216666666666667 2.1948097826087 1.90535010096565e-06 0.000117369566219484 GO:0023026 MHC class II protein complex binding 12/1840 27/18639 0.444444444444444 4.50217391304348 3.49015487124677e-06 0.000204755752446477 GO:0003743 translation initiation factor activity 17/1840 51/18639 0.333333333333333 3.37663043478261 4.16944768071721e-06 0.000233489070120164 GO:0051537 2 iron, 2 sulfur cluster binding 12/1840 28/18639 0.428571428571429 4.34138198757764 5.5594446037595e-06 0.000297569082862932 GO:0140597 protein carrier chaperone 39/1840 188/18639 0.207446808510638 2.10141362164662 5.79680031551166e-06 0.000297569082862932 GO:0016887 ATP hydrolysis activity 70/1840 417/18639 0.167865707434053 1.70046137003441 6.59899682210221e-06 0.000325198563393197 GO:0070182 DNA polymerase binding 10/1840 21/18639 0.476190476190476 4.82375776397515 1.08837089307526e-05 0.000515720361641816 GO:0140101 catalytic activity, acting on a tRNA 31/1840 139/18639 0.223021582733813 2.25918439161714 1.1313157762442e-05 0.000516215198641799 GO:0051087 protein-folding chaperone binding 30/1840 134/18639 0.223880597014925 2.26788611291369 1.43755467836576e-05 0.000632524058480935 GO:0140713 histone chaperone activity 34/1840 164/18639 0.207317073170732 2.10009941675504 2.27174872732097e-05 0.000965101528296357 GO:0045296 cadherin binding 57/1840 334/18639 0.170658682634731 1.72875390523301 2.8451147264161e-05 0.00116839378098155 GO:0023023 MHC protein complex binding 13/1840 37/18639 0.351351351351351 3.55915099882491 2.97160672704491e-05 0.00118097402829656 GO:0140097 catalytic activity, acting on DNA 57/1840 336/18639 0.169642857142857 1.71846370341615 3.38821706475362e-05 0.00130446356993014 GO:0043531 ADP binding 13/1840 38/18639 0.342105263157895 3.46548913043478 4.11078592117288e-05 0.0015235555514092 GO:0051287 NAD binding 16/1840 54/18639 0.296296296296296 3.00144927536232 4.20461759317474e-05 0.0015235555514092 GO:0060590 ATPase regulator activity 15/1840 49/18639 0.306122448979592 3.10098713398403 4.76238828366683e-05 0.00167636067585073 GO:0003954 NADH dehydrogenase activity 14/1840 44/18639 0.318181818181818 3.22314723320158 5.2593042126738e-05 0.0017755201470145 GO:0043024 ribosomal small subunit binding 9/1840 20/18639 0.45 4.55845108695652 5.33232511684548e-05 0.0017755201470145 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 17/1840 61/18639 0.278688524590164 2.82308446186743 5.8191429932587e-05 0.00188662741255124 GO:0016209 antioxidant activity 21/1840 86/18639 0.244186046511628 2.47357810920121 7.12331718213387e-05 0.00220107189597378 GO:0015399 primary active transmembrane transporter activity 33/1840 166/18639 0.198795180722892 2.01377357255107 7.14633732459018e-05 0.00220107189597378 GO:0044389 ubiquitin-like protein ligase binding 54/1840 322/18639 0.167701863354037 1.69880164731299 7.38771070658745e-05 0.00221991697329652 GO:0016874 ligase activity 33/1840 167/18639 0.197604790419162 2.00171504816454 8.07686755182127e-05 0.00236921448186757 GO:0005542 folic acid binding 7/1840 13/18639 0.538461538461538 5.45455685618729 9.06072674111674e-05 0.00259600356861763 GO:0031625 ubiquitin protein ligase binding 51/1840 302/18639 0.16887417218543 1.71067700835013 9.6470231879244e-05 0.00270116649261883 GO:0008137 NADH dehydrogenase (ubiquinone) activity 13/1840 41/18639 0.317073170731707 3.21191675503712 0.000100873111666735 0.00276168163496483 GO:0051536 iron-sulfur cluster binding 19/1840 76/18639 0.25 2.53247282608696 0.000110638152247571 0.00296317833845669 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 26/1840 122/18639 0.213114754098361 2.15882929436921 0.000124602970965112 0.00326618851551102 GO:0051540 metal cluster binding 19/1840 77/18639 0.246753246753247 2.49958356860531 0.000133459419013231 0.00342545842133961 GO:0140658 ATP-dependent chromatin remodeler activity 31/1840 158/18639 0.19620253164557 1.98751031920748 0.000149908042652198 0.00345089970128334 GO:0000510 H3-H4 histone complex chaperone activity 30/1840 151/18639 0.198675496688742 2.01256118629427 0.000150777773100454 0.00345089970128334 GO:0140584 chromatin extrusion motor activity 30/1840 151/18639 0.198675496688742 2.01256118629427 0.000150777773100454 0.00345089970128334 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 30/1840 151/18639 0.198675496688742 2.01256118629427 0.000150777773100454 0.00345089970128334 GO:0140849 ATP-dependent H2AZ histone chaperone activity 30/1840 151/18639 0.198675496688742 2.01256118629427 0.000150777773100454 0.00345089970128334 GO:0016879 ligase activity, forming carbon-nitrogen bonds 14/1840 48/18639 0.291666666666667 2.95455163043478 0.00015125696742638 0.00345089970128334 GO:0015616 DNA translocase activity 30/1840 152/18639 0.197368421052632 1.99932065217391 0.000170424340230859 0.00374933548507889 GO:0140674 ATP-dependent histone chaperone activity 30/1840 152/18639 0.197368421052632 1.99932065217391 0.000170424340230859 0.00374933548507889 GO:0003689 DNA clamp loader activity 31/1840 160/18639 0.19375 1.96266644021739 0.000190060395864278 0.0040160272528708 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 27/1840 132/18639 0.204545454545455 2.07202322134387 0.000191881957355977 0.0040160272528708 GO:0061775 cohesin loader activity 30/1840 153/18639 0.196078431372549 1.98625319693095 0.00019232598045404 0.0040160272528708 GO:0043022 ribosome binding 24/1840 112/18639 0.214285714285714 2.17069099378882 0.000204317936737109 0.00419532830100197 GO:0042826 histone deacetylase binding 26/1840 127/18639 0.204724409448819 2.07383601506333 0.000246333188683281 0.00491643777324073 GO:0008301 DNA binding, bending 8/1840 19/18639 0.421052631578947 4.26521739130435 0.000247418134692309 0.00491643777324073 GO:0016829 lyase activity 36/1840 200/18639 0.18 1.82338043478261 0.000280496024521401 0.00530740027508242 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 26/1840 128/18639 0.203125 2.05763417119565 0.000280592268124507 0.00530740027508242 GO:0016741 transferase activity, transferring one-carbon groups 38/1840 215/18639 0.176744186046512 1.79039939332659 0.000282490205710588 0.00530740027508242 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 7/1840 15/18639 0.466666666666667 4.72728260869565 0.000284325014736558 0.00530740027508242 GO:0030544 Hsp70 protein binding 14/1840 51/18639 0.274509803921569 2.78075447570333 0.0003055937925687 0.00561927690215878 GO:0004601 peroxidase activity 15/1840 57/18639 0.263157894736842 2.66576086956522 0.000312552028279896 0.00566270733589458 GO:0008094 ATP-dependent activity, acting on DNA 37/1840 210/18639 0.176190476190476 1.78479037267081 0.000359227220246745 0.00641402804846363 GO:0003713 transcription coactivator activity 43/1840 256/18639 0.16796875 1.70150518002717 0.000368548700533004 0.00648645712938088 GO:0042288 MHC class I protein binding 8/1840 20/18639 0.4 4.05195652173913 0.00037681472370821 0.00653853154378191 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 15/1840 58/18639 0.258620689655172 2.61979947526237 0.000383587343162157 0.00656360564966357 GO:0038024 cargo receptor activity 16/1840 65/18639 0.246153846153846 2.49351170568562 0.000454324029761297 0.00766749595432765 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 15/1840 59/18639 0.254237288135593 2.57539609432572 0.000468027862433668 0.0077920314394362 GO:0004386 helicase activity 29/1840 155/18639 0.187096774193548 1.89526998597475 0.000550652746221117 0.00904538911125889 GO:0140297 DNA-binding transcription factor binding 71/1840 488/18639 0.145491803278689 1.47381615288667 0.000559843376837728 0.00907535579294844 GO:0004519 endonuclease activity 25/1840 127/18639 0.196850393700787 1.99407309140705 0.0005957569234579 0.0095321107753264 GO:0030169 low-density lipoprotein particle binding 7/1840 17/18639 0.411764705882353 4.17113171355499 0.000719495199441428 0.0111196620665464 GO:0003684 damaged DNA binding 17/1840 74/18639 0.22972972972973 2.32713719153937 0.000721739845013531 0.0111196620665464 GO:0030515 snoRNA binding 10/1840 32/18639 0.3125 3.1655910326087 0.000722055978347171 0.0111196620665464 GO:0042277 peptide binding 41/1840 249/18639 0.164658634538153 1.66797407019382 0.000750592686759081 0.0114164220998418 GO:0140517 protein-RNA adaptor activity 8/1840 22/18639 0.363636363636364 3.68359683794466 0.00079903350451703 0.0120049911898168 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 53/1840 349/18639 0.151862464183381 1.53835025538807 0.00101553709155271 0.0150739963469029 GO:0016504 peptidase activator activity 14/1840 57/18639 0.245614035087719 2.48804347826087 0.0010354316674596 0.0151863311227408 GO:0097718 disordered domain specific binding 9/1840 28/18639 0.321428571428571 3.25603649068323 0.00105752506441414 0.0152596564626082 GO:0016830 carbon-carbon lyase activity 13/1840 51/18639 0.254901960784314 2.58212915601023 0.00106905702054852 0.0152596564626082 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 7/1840 18/18639 0.388888888888889 3.93940217391304 0.00107758937682379 0.0152596564626082 GO:0008171 O-methyltransferase activity 8/1840 23/18639 0.347826086956522 3.5234404536862 0.00112001110825533 0.0156801555155746 GO:0033218 amide binding 40/1840 247/18639 0.161943319838057 1.64046822742475 0.00119799381206602 0.0165411307793012 GO:0019887 protein kinase regulator activity 41/1840 255/18639 0.16078431372549 1.62872762148338 0.00120836182640999 0.0165411307793012 GO:0019207 kinase regulator activity 45/1840 287/18639 0.156794425087108 1.58831048326011 0.00122277666965746 0.0165545149122857 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 11/1840 40/18639 0.275 2.78572010869565 0.00130463014960377 0.017470699394694 GO:0003712 transcription coregulator activity 70/1840 495/18639 0.141414141414141 1.43250988142292 0.00132375697564708 0.0175362214408302 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 5/1840 10/18639 0.5 5.06494565217391 0.00153568687700554 0.0199154340260086 GO:0031720 haptoglobin binding 5/1840 10/18639 0.5 5.06494565217391 0.00153568687700554 0.0199154340260086 GO:0016651 oxidoreductase activity, acting on NAD(P)H 18/1840 88/18639 0.204545454545455 2.07202322134387 0.00211719551251655 0.0271706757439624 GO:0042393 histone binding 39/1840 247/18639 0.157894736842105 1.59945652173913 0.00219270892326414 0.0278496638501178 GO:0070990 snRNP binding 5/1840 11/18639 0.454545454545455 4.60449604743083 0.00258738719573937 0.0321985962136456 GO:1990948 ubiquitin ligase inhibitor activity 5/1840 11/18639 0.454545454545455 4.60449604743083 0.00258738719573937 0.0321985962136456 GO:0031369 translation initiation factor binding 9/1840 32/18639 0.28125 2.84903192934783 0.00299077038184145 0.0361238148081242 GO:0071813 lipoprotein particle binding 9/1840 32/18639 0.28125 2.84903192934783 0.00299077038184145 0.0361238148081242 GO:0071814 protein-lipid complex binding 9/1840 32/18639 0.28125 2.84903192934783 0.00299077038184145 0.0361238148081242 GO:0005159 insulin-like growth factor receptor binding 6/1840 16/18639 0.375 3.79870923913043 0.00307220311795316 0.0367471285564882 GO:0001671 ATPase activator activity 8/1840 27/18639 0.296296296296296 3.00144927536232 0.00354653119551196 0.041612632694007 GO:0004364 glutathione transferase activity 8/1840 27/18639 0.296296296296296 3.00144927536232 0.00354653119551196 0.041612632694007 GO:0016922 nuclear receptor binding 24/1840 137/18639 0.175182481751825 1.77457949857188 0.00389201257649147 0.0452354669267688 GO:0061133 endopeptidase activator activity 7/1840 22/18639 0.318181818181818 3.22314723320158 0.00405906626436202 0.0456652934295126 GO:0070034 telomerase RNA binding 7/1840 22/18639 0.318181818181818 3.22314723320158 0.00405906626436202 0.0456652934295126 GO:0004300 enoyl-CoA hydratase activity 5/1840 12/18639 0.416666666666667 4.22078804347826 0.00407725834192077 0.0456652934295126 GO:1990247 N6-methyladenosine-containing RNA reader activity 5/1840 12/18639 0.416666666666667 4.22078804347826 0.00407725834192077 0.0456652934295126 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 11/1840 46/18639 0.239130434782609 2.42236531190926 0.00433982664193192 0.0474864952438774 GO:0004029 aldehyde dehydrogenase (NAD+) activity 6/1840 17/18639 0.352941176470588 3.5752557544757 0.00435549834623227 0.0474864952438774 GO:0004549 tRNA-specific ribonuclease activity 6/1840 17/18639 0.352941176470588 3.5752557544757 0.00435549834623227 0.0474864952438774 GO:0004518 nuclease activity 33/1840 209/18639 0.157894736842105 1.59945652173913 0.00457694881731954 0.048815003688592 GO:0004521 RNA endonuclease activity 15/1840 73/18639 0.205479452054795 2.08148451459202 0.00458141067321875 0.048815003688592 GO:0000049 tRNA binding 16/1840 80/18639 0.2 2.02597826086957 0.00459621787977002 0.048815003688592 GO:0016860 intramolecular oxidoreductase activity 12/1840 53/18639 0.226415094339623 2.29356029532404 0.004755435630551 0.0500743307422123 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 13/1840 60/18639 0.216666666666667 2.1948097826087 0.00502618479482326 0.0524767768408666 GO:0008173 RNA methyltransferase activity 14/1840 67/18639 0.208955223880597 2.11669370538611 0.00517770568868412 0.0535405716591189 GO:0001618 virus receptor activity 16/1840 81/18639 0.197530864197531 2.00096618357488 0.00521499074601808 0.0535405716591189 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 12/1840 54/18639 0.222222222222222 2.25108695652174 0.00557668364164383 0.0563153626762722 GO:0017069 snRNA binding 12/1840 54/18639 0.222222222222222 2.25108695652174 0.00557668364164383 0.0563153626762722 GO:0003727 single-stranded RNA binding 17/1840 89/18639 0.191011235955056 1.93492305813385 0.005781910737942 0.0572493479667735 GO:0140272 exogenous protein binding 16/1840 82/18639 0.195121951219512 1.97656415694592 0.00589975477545518 0.0572493479667735 GO:1990841 promoter-specific chromatin binding 14/1840 68/18639 0.205882352941176 2.08556585677749 0.00594144438001489 0.0572493479667735 GO:0003725 double-stranded RNA binding 15/1840 75/18639 0.2 2.02597826086957 0.00595925490929342 0.0572493479667735 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 6/1840 18/18639 0.333333333333333 3.37663043478261 0.00599445283093651 0.0572493479667735 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 6/1840 18/18639 0.333333333333333 3.37663043478261 0.00599445283093651 0.0572493479667735 GO:0070628 proteasome binding 6/1840 18/18639 0.333333333333333 3.37663043478261 0.00599445283093651 0.0572493479667735 GO:0009982 pseudouridine synthase activity 5/1840 13/18639 0.384615384615385 3.89611204013378 0.00609190774493881 0.0577325410904971 GO:0035198 miRNA binding 10/1840 42/18639 0.238095238095238 2.41187888198758 0.00662120386439909 0.0622696424499212 GO:0055106 ubiquitin-protein transferase regulator activity 9/1840 36/18639 0.25 2.53247282608696 0.00700479637791677 0.0653780995272231 GO:0035925 mRNA 3'-UTR AU-rich region binding 8/1840 30/18639 0.266666666666667 2.70130434782609 0.00716122888158425 0.0663355938504646 GO:0005344 oxygen carrier activity 5/1840 14/18639 0.357142857142857 3.61781832298137 0.00871526407861211 0.0789500393003685 GO:0070742 C2H2 zinc finger domain binding 5/1840 14/18639 0.357142857142857 3.61781832298137 0.00871526407861211 0.0789500393003685 GO:0098847 sequence-specific single stranded DNA binding 5/1840 14/18639 0.357142857142857 3.61781832298137 0.00871526407861211 0.0789500393003685 GO:0022804 active transmembrane transporter activity 61/1840 457/18639 0.133479212253829 1.35212991152126 0.00922413742323893 0.0829499073389078 GO:0019205 nucleobase-containing compound kinase activity 10/1840 44/18639 0.227272727272727 2.30224802371541 0.00931776697440805 0.0831847022642806 GO:0061980 regulatory RNA binding 12/1840 58/18639 0.206896551724138 2.0958395802099 0.0100443087779271 0.0890258159309795 GO:0042887 amide transmembrane transporter activity 9/1840 38/18639 0.236842105263158 2.3991847826087 0.0101400227347138 0.0892322000654813 GO:0004722 protein serine/threonine phosphatase activity 18/1840 103/18639 0.174757281553398 1.77027226677923 0.0116787698189094 0.0964022550962715 GO:0000774 adenyl-nucleotide exchange factor activity 5/1840 15/18639 0.333333333333333 3.37663043478261 0.0120261158358913 0.0964022550962715 GO:0004129 cytochrome-c oxidase activity 5/1840 15/18639 0.333333333333333 3.37663043478261 0.0120261158358913 0.0964022550962715 GO:0055105 ubiquitin-protein transferase inhibitor activity 5/1840 15/18639 0.333333333333333 3.37663043478261 0.0120261158358913 0.0964022550962715 GO:0140776 protein-containing complex destabilizing activity 5/1840 15/18639 0.333333333333333 3.37663043478261 0.0120261158358913 0.0964022550962715 GO:0000217 DNA secondary structure binding 9/1840 39/18639 0.230769230769231 2.33766722408027 0.0120553205923999 0.0964022550962715 GO:0016776 phosphotransferase activity, phosphate group as acceptor 9/1840 39/18639 0.230769230769231 2.33766722408027 0.0120553205923999 0.0964022550962715 GO:0033192 calmodulin-dependent protein phosphatase activity 15/1840 81/18639 0.185185185185185 1.87590579710145 0.0121781966957681 0.0964022550962715 GO:0140791 histone H2AXS140 phosphatase activity 15/1840 81/18639 0.185185185185185 1.87590579710145 0.0121781966957681 0.0964022550962715 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 15/1840 81/18639 0.185185185185185 1.87590579710145 0.0121781966957681 0.0964022550962715 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 15/1840 81/18639 0.185185185185185 1.87590579710145 0.0121781966957681 0.0964022550962715 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 15/1840 81/18639 0.185185185185185 1.87590579710145 0.0121781966957681 0.0964022550962715 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 15/1840 81/18639 0.185185185185185 1.87590579710145 0.0121781966957681 0.0964022550962715 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 15/1840 81/18639 0.185185185185185 1.87590579710145 0.0121781966957681 0.0964022550962715 GO:1990439 MAP kinase serine/threonine phosphatase activity 15/1840 81/18639 0.185185185185185 1.87590579710145 0.0121781966957681 0.0964022550962715 GO:0005345 purine nucleobase transmembrane transporter activity 4/1840 10/18639 0.4 4.05195652173913 0.012206779054398 0.0964022550962715 GO:0140311 protein sequestering activity 8/1840 33/18639 0.242424242424242 2.45573122529644 0.0130289809697995 0.102240156399956 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 15/1840 82/18639 0.182926829268293 1.8530288971368 0.0135838180212113 0.104495985118385 GO:0033549 MAP kinase phosphatase activity 15/1840 82/18639 0.182926829268293 1.8530288971368 0.0135838180212113 0.104495985118385 GO:0005044 scavenger receptor activity 7/1840 27/18639 0.259259259259259 2.62626811594203 0.0136557253279708 0.104495985118385 GO:0015252 proton channel activity 7/1840 27/18639 0.259259259259259 2.62626811594203 0.0136557253279708 0.104495985118385 GO:0030331 nuclear estrogen receptor binding 9/1840 40/18639 0.225 2.27922554347826 0.0142276888914739 0.108200695767258 GO:0004540 RNA nuclease activity 20/1840 121/18639 0.165289256198347 1.67436219906576 0.014811184453952 0.110790702296717 GO:0061749 forked DNA-dependent helicase activity 10/1840 47/18639 0.212765957446809 2.15529602220167 0.0148380404861674 0.110790702296717 GO:1990518 single-stranded 3'-5' DNA helicase activity 10/1840 47/18639 0.212765957446809 2.15529602220167 0.0148380404861674 0.110790702296717 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 15/1840 83/18639 0.180722891566265 1.8307032477737 0.0151121347444233 0.112157530151383 GO:0016831 carboxy-lyase activity 8/1840 34/18639 0.235294117647059 2.38350383631714 0.0156007644815142 0.115090669707937 GO:0016675 oxidoreductase activity, acting on a heme group of donors 5/1840 16/18639 0.3125 3.1655910326087 0.0160960761622268 0.117339442792091 GO:0017070 U6 snRNA binding 5/1840 16/18639 0.3125 3.1655910326087 0.0160960761622268 0.117339442792091 GO:0002039 p53 binding 13/1840 69/18639 0.188405797101449 1.90853024574669 0.0164072679185587 0.117911895537788 GO:0001530 lipopolysaccharide binding 9/1840 41/18639 0.219512195121951 2.22363467656416 0.0166758226378361 0.117911895537788 GO:0042287 MHC protein binding 9/1840 41/18639 0.219512195121951 2.22363467656416 0.0166758226378361 0.117911895537788 GO:0016866 intramolecular transferase activity 7/1840 28/18639 0.25 2.53247282608696 0.0166935892213107 0.117911895537788 GO:0004860 protein kinase inhibitor activity 15/1840 84/18639 0.178571428571429 1.80890916149068 0.0167697353712552 0.117911895537788 GO:0017018 myosin phosphatase activity 15/1840 84/18639 0.178571428571429 1.80890916149068 0.0167697353712552 0.117911895537788 GO:0008649 rRNA methyltransferase activity 6/1840 22/18639 0.272727272727273 2.7626976284585 0.0171116401768712 0.117911895537788 GO:0009378 four-way junction helicase activity 10/1840 48/18639 0.208333333333333 2.11039402173913 0.0171316796276493 0.117911895537788 GO:0036121 double-stranded DNA helicase activity 10/1840 48/18639 0.208333333333333 2.11039402173913 0.0171316796276493 0.117911895537788 GO:0043138 3'-5' DNA helicase activity 10/1840 48/18639 0.208333333333333 2.11039402173913 0.0171316796276493 0.117911895537788 GO:0008168 methyltransferase activity 30/1840 204/18639 0.147058823529412 1.48968989769821 0.017365550888943 0.118536976432142 GO:0003724 RNA helicase activity 14/1840 77/18639 0.181818181818182 1.84179841897233 0.0176116793908626 0.118536976432142 GO:0015205 nucleobase transmembrane transporter activity 4/1840 11/18639 0.363636363636364 3.68359683794466 0.017703574402203 0.118536976432142 GO:0034511 U3 snoRNA binding 4/1840 11/18639 0.363636363636364 3.68359683794466 0.017703574402203 0.118536976432142 GO:0042608 T cell receptor binding 4/1840 11/18639 0.363636363636364 3.68359683794466 0.017703574402203 0.118536976432142 GO:0051879 Hsp90 protein binding 9/1840 42/18639 0.214285714285714 2.17069099378882 0.0194179913942279 0.129313326473994 GO:0004550 nucleoside diphosphate kinase activity 5/1840 17/18639 0.294117647058824 2.97937979539642 0.0209879835855578 0.138273774210734 GO:1990226 histone methyltransferase binding 5/1840 17/18639 0.294117647058824 2.97937979539642 0.0209879835855578 0.138273774210734 GO:0140102 catalytic activity, acting on a rRNA 6/1840 23/18639 0.260869565217391 2.64258034026465 0.0212646062762991 0.139351036874471 GO:0008186 ATP-dependent activity, acting on RNA 14/1840 79/18639 0.177215189873418 1.79517061089708 0.0217011420928535 0.139951283941898 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 8/1840 36/18639 0.222222222222222 2.25108695652174 0.0218105897052309 0.139951283941898 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 8/1840 36/18639 0.222222222222222 2.25108695652174 0.0218105897052309 0.139951283941898 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 8/1840 36/18639 0.222222222222222 2.25108695652174 0.0218105897052309 0.139951283941898 GO:0048156 tau protein binding 9/1840 43/18639 0.209302325581395 2.12020980788675 0.0224718654496986 0.143447348362843 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 25/1840 167/18639 0.149700598802395 1.51645079406405 0.0229937582627037 0.146022217420881 GO:0008603 cAMP-dependent protein kinase regulator activity 4/1840 12/18639 0.333333333333333 3.37663043478261 0.0245167324323441 0.153322915515979 GO:0016423 tRNA (guanine) methyltransferase activity 4/1840 12/18639 0.333333333333333 3.37663043478261 0.0245167324323441 0.153322915515979 GO:0097677 STAT family protein binding 4/1840 12/18639 0.333333333333333 3.37663043478261 0.0245167324323441 0.153322915515979 GO:0017116 single-stranded DNA helicase activity 11/1840 58/18639 0.189655172413793 1.92118628185907 0.0248944547851935 0.154898829774537 GO:0015295 solute:proton symporter activity 6/1840 24/18639 0.25 2.53247282608696 0.0260483847847918 0.158869356707245 GO:0042625 ATPase-coupled ion transmembrane transporter activity 6/1840 24/18639 0.25 2.53247282608696 0.0260483847847918 0.158869356707245 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 6/1840 24/18639 0.25 2.53247282608696 0.0260483847847918 0.158869356707245 GO:0046961 proton-transporting ATPase activity, rotational mechanism 6/1840 24/18639 0.25 2.53247282608696 0.0260483847847918 0.158869356707245 GO:0000400 four-way junction DNA binding 5/1840 18/18639 0.277777777777778 2.81385869565217 0.0267547261834891 0.160789378819798 GO:0035615 clathrin adaptor activity 5/1840 18/18639 0.277777777777778 2.81385869565217 0.0267547261834891 0.160789378819798 GO:1990381 ubiquitin-specific protease binding 5/1840 18/18639 0.277777777777778 2.81385869565217 0.0267547261834891 0.160789378819798 GO:0003678 DNA helicase activity 13/1840 74/18639 0.175675675675676 1.77957549941246 0.028119782565494 0.167360251790766 GO:0031491 nucleosome binding 13/1840 74/18639 0.175675675675676 1.77957549941246 0.028119782565494 0.167360251790766 GO:0072349 modified amino acid transmembrane transporter activity 7/1840 31/18639 0.225806451612903 2.28739481065919 0.0286057937096689 0.169434316588039 GO:0042162 telomeric DNA binding 8/1840 38/18639 0.210526315789474 2.13260869565217 0.0295867778934586 0.174406269687756 GO:0019210 kinase inhibitor activity 15/1840 90/18639 0.166666666666667 1.6883152173913 0.0297964292859852 0.17480571847778 GO:0072341 modified amino acid binding 15/1840 91/18639 0.164835164835165 1.66976230291448 0.0325404281695951 0.1848313278641 GO:0140296 general transcription initiation factor binding 10/1840 53/18639 0.188679245283019 1.91130024610336 0.0326494379492133 0.1848313278641 GO:0002161 aminoacyl-tRNA editing activity 4/1840 13/18639 0.307692307692308 3.11688963210702 0.0327055434045241 0.1848313278641 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 4/1840 13/18639 0.307692307692308 3.11688963210702 0.0327055434045241 0.1848313278641 GO:0008035 high-density lipoprotein particle binding 4/1840 13/18639 0.307692307692308 3.11688963210702 0.0327055434045241 0.1848313278641 GO:0019104 DNA N-glycosylase activity 4/1840 13/18639 0.307692307692308 3.11688963210702 0.0327055434045241 0.1848313278641 GO:0035673 oligopeptide transmembrane transporter activity 4/1840 13/18639 0.307692307692308 3.11688963210702 0.0327055434045241 0.1848313278641 GO:0140666 annealing activity 4/1840 13/18639 0.307692307692308 3.11688963210702 0.0327055434045241 0.1848313278641 GO:0097001 ceramide binding 5/1840 19/18639 0.263157894736842 2.66576086956522 0.0334384616836531 0.188110432850505 GO:0140142 nucleocytoplasmic carrier activity 7/1840 32/18639 0.21875 2.21591372282609 0.0335966164819262 0.188141052298787 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 8/1840 39/18639 0.205128205128205 2.07792642140468 0.034111024938893 0.189300823084307 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 8/1840 39/18639 0.205128205128205 2.07792642140468 0.034111024938893 0.189300823084307 GO:0003925 G protein activity 10/1840 54/18639 0.185185185185185 1.87590579710145 0.0366548547028019 0.202505744367049 GO:0008198 ferrous iron binding 6/1840 26/18639 0.230769230769231 2.33766722408027 0.0376339792647147 0.206066944240571 GO:0050750 low-density lipoprotein particle receptor binding 6/1840 26/18639 0.230769230769231 2.33766722408027 0.0376339792647147 0.206066944240571 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 8/1840 40/18639 0.2 2.02597826086957 0.0390818589507478 0.212392766486893 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 7/1840 33/18639 0.212121212121212 2.14876482213439 0.0391340568121141 0.212392766486893 GO:0140313 molecular sequestering activity 10/1840 55/18639 0.181818181818182 1.84179841897233 0.0409880755393719 0.219993399861514 GO:0000339 RNA cap binding 5/1840 20/18639 0.25 2.53247282608696 0.0410701964027178 0.219993399861514 GO:0061608 nuclear import signal receptor activity 5/1840 20/18639 0.25 2.53247282608696 0.0410701964027178 0.219993399861514 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 9/1840 48/18639 0.1875 1.89935461956522 0.042972916883712 0.228201006899712 GO:0038187 pattern recognition receptor activity 9/1840 48/18639 0.1875 1.89935461956522 0.042972916883712 0.228201006899712 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 6/1840 27/18639 0.222222222222222 2.25108695652174 0.0444849089609273 0.235216342660354 GO:0016835 carbon-oxygen lyase activity 13/1840 79/18639 0.164556962025316 1.66694413869015 0.0450006501987064 0.23692650019148 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 7/1840 34/18639 0.205882352941176 2.08556585677749 0.0452352807496771 0.237148365462137 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 5/1840 21/18639 0.238095238095238 2.41187888198758 0.0496696804999291 0.258198507915243 GO:0140312 cargo adaptor activity 5/1840 21/18639 0.238095238095238 2.41187888198758 0.0496696804999291 0.258198507915243 GO:0016859 cis-trans isomerase activity 8/1840 42/18639 0.19047619047619 1.92950310559006 0.0504184803732608 0.260989780755703 GO:0016229 steroid dehydrogenase activity 7/1840 35/18639 0.2 2.02597826086957 0.0519139975845283 0.266154735570015 GO:0019789 SUMO transferase activity 6/1840 28/18639 0.214285714285714 2.17069099378882 0.0520643597990045 0.266154735570015 GO:0046625 sphingolipid binding 6/1840 28/18639 0.214285714285714 2.17069099378882 0.0520643597990045 0.266154735570015 GO:0043539 protein serine/threonine kinase activator activity 12/1840 73/18639 0.164383561643836 1.66518761167362 0.0530686293682114 0.270167567692713 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 8/1840 43/18639 0.186046511627907 1.88463094034378 0.056806278070075 0.288005492108364 GO:0031593 polyubiquitin modification-dependent protein binding 10/1840 59/18639 0.169491525423729 1.71693072955048 0.061778868376156 0.310659452405813 GO:0036002 pre-mRNA binding 10/1840 59/18639 0.169491525423729 1.71693072955048 0.061778868376156 0.310659452405813 GO:0000062 fatty-acyl-CoA binding 4/1840 16/18639 0.25 2.53247282608696 0.0657158974828661 0.312365922102176 GO:0003688 DNA replication origin binding 4/1840 16/18639 0.25 2.53247282608696 0.0657158974828661 0.312365922102176 GO:0097027 ubiquitin-protein transferase activator activity 4/1840 16/18639 0.25 2.53247282608696 0.0657158974828661 0.312365922102176 GO:0005080 protein kinase C binding 9/1840 52/18639 0.173076923076923 1.7532504180602 0.0664031938555305 0.312365922102176 GO:0019001 guanyl nucleotide binding 49/1840 400/18639 0.1225 1.24091168478261 0.0665612069327429 0.312365922102176 GO:0032561 guanyl ribonucleotide binding 49/1840 400/18639 0.1225 1.24091168478261 0.0665612069327429 0.312365922102176 GO:0004527 exonuclease activity 13/1840 84/18639 0.154761904761905 1.56772127329193 0.0678989267121075 0.312365922102176 GO:0001094 TFIID-class transcription factor complex binding 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:0003680 minor groove of adenine-thymine-rich DNA binding 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:0004862 cAMP-dependent protein kinase inhibitor activity 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:0005528 FK506 binding 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:0008190 eukaryotic initiation factor 4E binding 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:0030957 Tat protein binding 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:0032356 oxidized DNA binding 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:0032395 MHC class II receptor activity 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:0043295 glutathione binding 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:0051880 G-quadruplex DNA binding 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:0097177 mitochondrial ribosome binding 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:0140940 histone H2A methyltransferase activity 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:0141109 transporter activator activity 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:1990259 histone H2AQ104 methyltransferase activity 3/1840 10/18639 0.3 3.03896739130435 0.0679497298079408 0.312365922102176 GO:0016769 transferase activity, transferring nitrogenous groups 6/1840 30/18639 0.2 2.02597826086957 0.0694425115070812 0.317300662237401 GO:0042171 lysophosphatidic acid acyltransferase activity 5/1840 23/18639 0.217391304347826 2.20215028355388 0.069795843722675 0.317300662237401 GO:0071617 lysophospholipid acyltransferase activity 5/1840 23/18639 0.217391304347826 2.20215028355388 0.069795843722675 0.317300662237401 GO:0046915 transition metal ion transmembrane transporter activity 8/1840 45/18639 0.177777777777778 1.80086956521739 0.0710581214986521 0.32067254830161 GO:0051539 4 iron, 4 sulfur cluster binding 8/1840 45/18639 0.177777777777778 1.80086956521739 0.0710581214986521 0.32067254830161 GO:1901505 carbohydrate derivative transmembrane transporter activity 9/1840 53/18639 0.169811320754717 1.72017022149303 0.0733073712000045 0.329615625249655 GO:0019903 protein phosphatase binding 20/1840 144/18639 0.138888888888889 1.40692934782609 0.0740183046101907 0.331602004653654 GO:0016836 hydro-lyase activity 10/1840 61/18639 0.163934426229508 1.66063791874555 0.074342525244992 0.331847793847211 GO:0002020 protease binding 19/1840 136/18639 0.139705882352941 1.4152054028133 0.0764600104228621 0.338844362737288 GO:0140789 histone phosphatase activity 19/1840 136/18639 0.139705882352941 1.4152054028133 0.0764600104228621 0.338844362737288 GO:0030291 protein serine/threonine kinase inhibitor activity 8/1840 46/18639 0.173913043478261 1.7617202268431 0.0789297332340587 0.344779245333565 GO:0008327 methyl-CpG binding 6/1840 31/18639 0.193548387096774 1.96062412342216 0.07924332377846 0.344779245333565 GO:0070325 lipoprotein particle receptor binding 6/1840 31/18639 0.193548387096774 1.96062412342216 0.07924332377846 0.344779245333565 GO:0005092 GDP-dissociation inhibitor activity 4/1840 17/18639 0.235294117647059 2.38350383631714 0.0794783325281919 0.344779245333565 GO:0048038 quinone binding 4/1840 17/18639 0.235294117647059 2.38350383631714 0.0794783325281919 0.344779245333565 GO:1901567 fatty acid derivative binding 4/1840 17/18639 0.235294117647059 2.38350383631714 0.0794783325281919 0.344779245333565 GO:0005525 GTP binding 46/1840 378/18639 0.121693121693122 1.2327380952381 0.07990395903291 0.345409394837 GO:0001091 RNA polymerase II general transcription initiation factor binding 5/1840 24/18639 0.208333333333333 2.11039402173913 0.0813083329168547 0.347818979699878 GO:0004622 lysophospholipase activity 5/1840 24/18639 0.208333333333333 2.11039402173913 0.0813083329168547 0.347818979699878 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 5/1840 24/18639 0.208333333333333 2.11039402173913 0.0813083329168547 0.347818979699878 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 3/1840 11/18639 0.272727272727273 2.7626976284585 0.0867920380850927 0.362467087867234 GO:0015173 aromatic amino acid transmembrane transporter activity 3/1840 11/18639 0.272727272727273 2.7626976284585 0.0867920380850927 0.362467087867234 GO:0015217 ADP transmembrane transporter activity 3/1840 11/18639 0.272727272727273 2.7626976284585 0.0867920380850927 0.362467087867234 GO:0019864 IgG binding 3/1840 11/18639 0.272727272727273 2.7626976284585 0.0867920380850927 0.362467087867234 GO:0032404 mismatch repair complex binding 3/1840 11/18639 0.272727272727273 2.7626976284585 0.0867920380850927 0.362467087867234 GO:0050786 RAGE receptor binding 3/1840 11/18639 0.272727272727273 2.7626976284585 0.0867920380850927 0.362467087867234 GO:1900750 oligopeptide binding 3/1840 11/18639 0.272727272727273 2.7626976284585 0.0867920380850927 0.362467087867234 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 6/1840 32/18639 0.1875 1.89935461956522 0.0897771793084294 0.373667178743193 GO:0008483 transaminase activity 5/1840 25/18639 0.2 2.02597826086957 0.0937614880290763 0.384409290785702 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 5/1840 25/18639 0.2 2.02597826086957 0.0937614880290763 0.384409290785702 GO:0015036 disulfide oxidoreductase activity 7/1840 40/18639 0.175 1.77273097826087 0.0941966559397999 0.384409290785702 GO:0016854 racemase and epimerase activity 4/1840 18/18639 0.222222222222222 2.25108695652174 0.0945422200552497 0.384409290785702 GO:0030228 lipoprotein particle receptor activity 4/1840 18/18639 0.222222222222222 2.25108695652174 0.0945422200552497 0.384409290785702 GO:0031690 adrenergic receptor binding 4/1840 18/18639 0.222222222222222 2.25108695652174 0.0945422200552497 0.384409290785702 GO:1901611 phosphatidylglycerol binding 4/1840 18/18639 0.222222222222222 2.25108695652174 0.0945422200552497 0.384409290785702 GO:0004721 phosphoprotein phosphatase activity 23/1840 175/18639 0.131428571428571 1.33135714285714 0.095189934920239 0.385769736255705 GO:0030170 pyridoxal phosphate binding 9/1840 56/18639 0.160714285714286 1.62801824534161 0.0965790343822828 0.390115968390074 GO:0070279 vitamin B6 binding 9/1840 57/18639 0.157894736842105 1.59945652173913 0.105185830547814 0.419310706040811 GO:0020037 heme binding 19/1840 142/18639 0.133802816901408 1.35540799142682 0.105935887916896 0.419310706040811 GO:0004526 ribonuclease P activity 3/1840 12/18639 0.25 2.53247282608696 0.107550473302675 0.419310706040811 GO:0004875 complement receptor activity 3/1840 12/18639 0.25 2.53247282608696 0.107550473302675 0.419310706040811 GO:0005527 macrolide binding 3/1840 12/18639 0.25 2.53247282608696 0.107550473302675 0.419310706040811 GO:0035259 nuclear glucocorticoid receptor binding 3/1840 12/18639 0.25 2.53247282608696 0.107550473302675 0.419310706040811 GO:0036009 protein-glutamine N-methyltransferase activity 3/1840 12/18639 0.25 2.53247282608696 0.107550473302675 0.419310706040811 GO:0043047 single-stranded telomeric DNA binding 3/1840 12/18639 0.25 2.53247282608696 0.107550473302675 0.419310706040811 GO:0045295 gamma-catenin binding 3/1840 12/18639 0.25 2.53247282608696 0.107550473302675 0.419310706040811 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 3/1840 12/18639 0.25 2.53247282608696 0.107550473302675 0.419310706040811 GO:0097371 MDM2/MDM4 family protein binding 3/1840 12/18639 0.25 2.53247282608696 0.107550473302675 0.419310706040811 GO:0048029 monosaccharide binding 11/1840 74/18639 0.148648648648649 1.505794653349 0.109800755477567 0.424070299767339 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 4/1840 19/18639 0.210526315789474 2.13260869565217 0.110836555621009 0.424070299767339 GO:0005346 purine ribonucleotide transmembrane transporter activity 4/1840 19/18639 0.210526315789474 2.13260869565217 0.110836555621009 0.424070299767339 GO:0050145 nucleoside monophosphate kinase activity 4/1840 19/18639 0.210526315789474 2.13260869565217 0.110836555621009 0.424070299767339 GO:0120227 acyl-CoA binding 4/1840 19/18639 0.210526315789474 2.13260869565217 0.110836555621009 0.424070299767339 GO:0140036 ubiquitin-modified protein reader activity 4/1840 19/18639 0.210526315789474 2.13260869565217 0.110836555621009 0.424070299767339 GO:0008175 tRNA methyltransferase activity 6/1840 34/18639 0.176470588235294 1.78762787723785 0.112987476339866 0.426995616106489 GO:0015035 protein-disulfide reductase activity 6/1840 34/18639 0.176470588235294 1.78762787723785 0.112987476339866 0.426995616106489 GO:0019825 oxygen binding 6/1840 34/18639 0.176470588235294 1.78762787723785 0.112987476339866 0.426995616106489 GO:0090482 vitamin transmembrane transporter activity 6/1840 34/18639 0.176470588235294 1.78762787723785 0.112987476339866 0.426995616106489 GO:0008408 3'-5' exonuclease activity 9/1840 58/18639 0.155172413793103 1.57187968515742 0.114211274554877 0.430300581809201 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 10/1840 67/18639 0.149253731343284 1.51192407527579 0.120949297658225 0.454297361935773 GO:0005385 zinc ion transmembrane transporter activity 5/1840 27/18639 0.185185185185185 1.87590579710145 0.121361605962722 0.45446048190296 GO:0070063 RNA polymerase binding 9/1840 59/18639 0.152542372881356 1.54523765659543 0.123649107667047 0.461623335290307 GO:0052745 inositol phosphate phosphatase activity 4/1840 20/18639 0.2 2.02597826086957 0.128278145425582 0.47668115833111 GO:0017154 semaphorin receptor activity 3/1840 13/18639 0.230769230769231 2.33766722408027 0.130003952272121 0.47668115833111 GO:0035325 Toll-like receptor binding 3/1840 13/18639 0.230769230769231 2.33766722408027 0.130003952272121 0.47668115833111 GO:0051011 microtubule minus-end binding 3/1840 13/18639 0.230769230769231 2.33766722408027 0.130003952272121 0.47668115833111 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 3/1840 13/18639 0.230769230769231 2.33766722408027 0.130003952272121 0.47668115833111 GO:0097157 pre-mRNA intronic binding 3/1840 13/18639 0.230769230769231 2.33766722408027 0.130003952272121 0.47668115833111 GO:0001098 basal transcription machinery binding 9/1840 60/18639 0.15 1.51948369565217 0.133491423609709 0.486572289606988 GO:0001099 basal RNA polymerase II transcription machinery binding 9/1840 60/18639 0.15 1.51948369565217 0.133491423609709 0.486572289606988 GO:0046966 nuclear thyroid hormone receptor binding 5/1840 28/18639 0.178571428571429 1.80890916149068 0.136426224693965 0.495802680893703 GO:0043014 alpha-tubulin binding 7/1840 44/18639 0.159090909090909 1.61157361660079 0.138486871539384 0.501811252166237 GO:0000287 magnesium ion binding 28/1840 230/18639 0.121739130434783 1.23320415879017 0.1436190528418 0.518881739299405 GO:0001846 opsonin binding 4/1840 21/18639 0.19047619047619 1.92950310559006 0.146774254819853 0.527189160169267 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 4/1840 21/18639 0.19047619047619 1.92950310559006 0.146774254819853 0.527189160169267 GO:0003785 actin monomer binding 5/1840 29/18639 0.172413793103448 1.74653298350825 0.152268722023925 0.538729662037963 GO:0005347 ATP transmembrane transporter activity 3/1840 14/18639 0.214285714285714 2.17069099378882 0.153922760582275 0.538729662037963 GO:0008174 mRNA methyltransferase activity 3/1840 14/18639 0.214285714285714 2.17069099378882 0.153922760582275 0.538729662037963 GO:0008474 palmitoyl-(protein) hydrolase activity 3/1840 14/18639 0.214285714285714 2.17069099378882 0.153922760582275 0.538729662037963 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 3/1840 14/18639 0.214285714285714 2.17069099378882 0.153922760582275 0.538729662037963 GO:0030983 mismatched DNA binding 3/1840 14/18639 0.214285714285714 2.17069099378882 0.153922760582275 0.538729662037963 GO:0098599 palmitoyl hydrolase activity 3/1840 14/18639 0.214285714285714 2.17069099378882 0.153922760582275 0.538729662037963 GO:1901612 cardiolipin binding 3/1840 14/18639 0.214285714285714 2.17069099378882 0.153922760582275 0.538729662037963 GO:1990825 sequence-specific mRNA binding 3/1840 14/18639 0.214285714285714 2.17069099378882 0.153922760582275 0.538729662037963 GO:0019842 vitamin binding 19/1840 150/18639 0.126666666666667 1.28311956521739 0.15487193956976 0.540516231019672 GO:0042578 phosphoric ester hydrolase activity 42/1840 363/18639 0.115702479338843 1.17205353934603 0.156908547731458 0.546077205664282 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 8/1840 54/18639 0.148148148148148 1.50072463768116 0.159335705606535 0.551408958728232 GO:0140463 chromatin-protein adaptor activity 8/1840 54/18639 0.148148148148148 1.50072463768116 0.159335705606535 0.551408958728232 GO:0140035 ubiquitin-like protein reader activity 4/1840 22/18639 0.181818181818182 1.84179841897233 0.166225072621466 0.57363946630153 GO:0046906 tetrapyrrole binding 19/1840 152/18639 0.125 1.26623641304348 0.168779277222794 0.57541625683356 GO:0008106 alcohol dehydrogenase (NADP+) activity 5/1840 30/18639 0.166666666666667 1.6883152173913 0.168833964127294 0.57541625683356 GO:0008187 poly-pyrimidine tract binding 5/1840 30/18639 0.166666666666667 1.6883152173913 0.168833964127294 0.57541625683356 GO:0015215 nucleotide transmembrane transporter activity 5/1840 30/18639 0.166666666666667 1.6883152173913 0.168833964127294 0.57541625683356 GO:0015294 solute:monoatomic cation symporter activity 15/1840 116/18639 0.129310344827586 1.30989973763118 0.169075231309861 0.57541625683356 GO:0008374 O-acyltransferase activity 8/1840 55/18639 0.145454545454545 1.47343873517787 0.171410643775953 0.581757336451721 GO:0061134 peptidase regulator activity 27/1840 226/18639 0.119469026548673 1.2102082531743 0.172476001553344 0.583764928334395 GO:0004536 DNA nuclease activity 9/1840 64/18639 0.140625 1.42451596467391 0.176693597968236 0.593067959982984 GO:0019902 phosphatase binding 23/1840 190/18639 0.121052631578947 1.22625 0.178420626927446 0.593067959982984 GO:0005041 low-density lipoprotein particle receptor activity 3/1840 15/18639 0.2 2.02597826086957 0.179075715189667 0.593067959982984 GO:0015929 hexosaminidase activity 3/1840 15/18639 0.2 2.02597826086957 0.179075715189667 0.593067959982984 GO:0016846 carbon-sulfur lyase activity 3/1840 15/18639 0.2 2.02597826086957 0.179075715189667 0.593067959982984 GO:0050780 dopamine receptor binding 3/1840 15/18639 0.2 2.02597826086957 0.179075715189667 0.593067959982984 GO:0141050 histone H3K deacetylase activity 3/1840 15/18639 0.2 2.02597826086957 0.179075715189667 0.593067959982984 GO:0141051 histone H4K deacetylase activity 3/1840 15/18639 0.2 2.02597826086957 0.179075715189667 0.593067959982984 GO:0004857 enzyme inhibitor activity 47/1840 416/18639 0.112980769230769 1.1444829117893 0.182057199293273 0.601325655574565 GO:0005310 dicarboxylic acid transmembrane transporter activity 5/1840 31/18639 0.161290322580645 1.63385343618513 0.186062933425147 0.609549035311534 GO:0016411 acylglycerol O-acyltransferase activity 5/1840 31/18639 0.161290322580645 1.63385343618513 0.186062933425147 0.609549035311534 GO:0000295 adenine nucleotide transmembrane transporter activity 4/1840 23/18639 0.173913043478261 1.7617202268431 0.186525962915948 0.609549035311534 GO:0004602 glutathione peroxidase activity 4/1840 23/18639 0.173913043478261 1.7617202268431 0.186525962915948 0.609549035311534 GO:0140693 molecular condensate scaffold activity 7/1840 48/18639 0.145833333333333 1.47727581521739 0.191058105003419 0.62270789778892 GO:0001540 amyloid-beta binding 11/1840 83/18639 0.132530120481928 1.34251571503405 0.193296121924084 0.628339900291482 GO:0052689 carboxylic ester hydrolase activity 12/1840 92/18639 0.130434782608696 1.32129017013232 0.19440034936592 0.630266395838981 GO:0015932 nucleobase-containing compound transmembrane transporter activity 8/1840 57/18639 0.140350877192982 1.42173913043478 0.196731027348708 0.636148623867739 GO:0004177 aminopeptidase activity 6/1840 40/18639 0.15 1.51948369565217 0.197929781929747 0.638349453762952 GO:0032182 ubiquitin-like protein binding 15/1840 120/18639 0.125 1.26623641304348 0.203455251538959 0.65024998850863 GO:1902936 phosphatidylinositol bisphosphate binding 14/1840 111/18639 0.126126126126126 1.27764394829612 0.204183413466831 0.65024998850863 GO:0005521 lamin binding 3/1840 16/18639 0.1875 1.89935461956522 0.205235673122006 0.65024998850863 GO:0008296 3'-5'-DNA exonuclease activity 3/1840 16/18639 0.1875 1.89935461956522 0.205235673122006 0.65024998850863 GO:0016722 oxidoreductase activity, acting on metal ions 3/1840 16/18639 0.1875 1.89935461956522 0.205235673122006 0.65024998850863 GO:0030275 LRR domain binding 3/1840 16/18639 0.1875 1.89935461956522 0.205235673122006 0.65024998850863 GO:0016763 pentosyltransferase activity 7/1840 49/18639 0.142857142857143 1.44712732919255 0.205314322670338 0.65024998850863 GO:0019209 kinase activator activity 18/1840 148/18639 0.121621621621622 1.23201380728555 0.208021355982105 0.657134129666547 GO:0030295 protein kinase activator activity 17/1840 139/18639 0.122302158273381 1.2389075695965 0.209665689327567 0.6606346016664 GO:0003714 transcription corepressor activity 24/1840 204/18639 0.117647058823529 1.19175191815857 0.21033559383921 0.661054723494661 GO:0004812 aminoacyl-tRNA ligase activity 6/1840 41/18639 0.146341463414634 1.48242311770944 0.213959084800606 0.666677896506072 GO:0016875 ligase activity, forming carbon-oxygen bonds 6/1840 41/18639 0.146341463414634 1.48242311770944 0.213959084800606 0.666677896506072 GO:0042169 SH2 domain binding 6/1840 41/18639 0.146341463414634 1.48242311770944 0.213959084800606 0.666677896506072 GO:0098631 cell adhesion mediator activity 10/1840 76/18639 0.131578947368421 1.33288043478261 0.214289323876952 0.666677896506072 GO:0015605 organophosphate ester transmembrane transporter activity 7/1840 50/18639 0.14 1.4181847826087 0.219957955196933 0.682589926454967 GO:0140416 transcription regulator inhibitor activity 5/1840 33/18639 0.151515151515152 1.53483201581028 0.222261918293038 0.687283130873892 GO:0031406 carboxylic acid binding 22/1840 187/18639 0.117647058823529 1.19175191815857 0.222586013976204 0.687283130873892 GO:0001848 complement binding 4/1840 25/18639 0.16 1.62078260869565 0.229247203370375 0.697683627324581 GO:0008139 nuclear localization sequence binding 4/1840 25/18639 0.16 1.62078260869565 0.229247203370375 0.697683627324581 GO:0004520 DNA endonuclease activity 6/1840 42/18639 0.142857142857143 1.44712732919255 0.230414445243201 0.697683627324581 GO:0031492 nucleosomal DNA binding 6/1840 42/18639 0.142857142857143 1.44712732919255 0.230414445243201 0.697683627324581 GO:0042056 chemoattractant activity 6/1840 42/18639 0.142857142857143 1.44712732919255 0.230414445243201 0.697683627324581 GO:0043175 RNA polymerase core enzyme binding 6/1840 42/18639 0.142857142857143 1.44712732919255 0.230414445243201 0.697683627324581 GO:0008429 phosphatidylethanolamine binding 3/1840 17/18639 0.176470588235294 1.78762787723785 0.232183674677823 0.697683627324581 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 3/1840 17/18639 0.176470588235294 1.78762787723785 0.232183674677823 0.697683627324581 GO:0032183 SUMO binding 3/1840 17/18639 0.176470588235294 1.78762787723785 0.232183674677823 0.697683627324581 GO:0032977 membrane insertase activity 3/1840 17/18639 0.176470588235294 1.78762787723785 0.232183674677823 0.697683627324581 GO:0070403 NAD+ binding 3/1840 17/18639 0.176470588235294 1.78762787723785 0.232183674677823 0.697683627324581 GO:0008081 phosphoric diester hydrolase activity 11/1840 87/18639 0.126436781609195 1.28079085457271 0.237552553852374 0.709457076767362 GO:0043177 organic acid binding 22/1840 189/18639 0.116402116402116 1.17914078674948 0.2378118320227 0.709457076767362 GO:0030332 cyclin binding 5/1840 34/18639 0.147058823529412 1.48968989769821 0.241102339319447 0.709457076767362 GO:0001221 transcription coregulator binding 14/1840 115/18639 0.121739130434783 1.23320415879017 0.243123032117967 0.709457076767362 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 7/1840 52/18639 0.134615384615385 1.36363921404682 0.250280798040372 0.709457076767362 GO:0097110 scaffold protein binding 9/1840 70/18639 0.128571428571429 1.30241459627329 0.251398260440523 0.709457076767362 GO:0019905 syntaxin binding 8/1840 61/18639 0.131147540983607 1.32851033499644 0.251437571439281 0.709457076767362 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 4/1840 26/18639 0.153846153846154 1.55844481605351 0.251451207511895 0.709457076767362 GO:0008143 poly(A) binding 4/1840 26/18639 0.153846153846154 1.55844481605351 0.251451207511895 0.709457076767362 GO:0015216 purine nucleotide transmembrane transporter activity 4/1840 26/18639 0.153846153846154 1.55844481605351 0.251451207511895 0.709457076767362 GO:0034237 protein kinase A regulatory subunit binding 4/1840 26/18639 0.153846153846154 1.55844481605351 0.251451207511895 0.709457076767362 GO:0050681 nuclear androgen receptor binding 4/1840 26/18639 0.153846153846154 1.55844481605351 0.251451207511895 0.709457076767362 GO:0070006 metalloaminopeptidase activity 4/1840 26/18639 0.153846153846154 1.55844481605351 0.251451207511895 0.709457076767362 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0004090 carbonyl reductase (NADPH) activity 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0005031 tumor necrosis factor receptor activity 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0005337 nucleoside transmembrane transporter activity 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0005381 iron ion transmembrane transporter activity 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0008519 ammonium channel activity 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0015643 toxic substance binding 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0031996 thioesterase binding 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0033204 ribonuclease P RNA binding 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0043208 glycosphingolipid binding 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0043422 protein kinase B binding 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0045322 unmethylated CpG binding 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0098505 G-rich strand telomeric DNA binding 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:1905394 retromer complex binding 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:1990757 ubiquitin ligase activator activity 2/1840 10/18639 0.2 2.02597826086957 0.258925443026145 0.709457076767362 GO:0000900 mRNA regulatory element binding translation repressor activity 3/1840 18/18639 0.166666666666667 1.6883152173913 0.259711965602338 0.709457076767362 GO:0008409 5'-3' exonuclease activity 3/1840 18/18639 0.166666666666667 1.6883152173913 0.259711965602338 0.709457076767362 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 3/1840 18/18639 0.166666666666667 1.6883152173913 0.259711965602338 0.709457076767362 GO:0017075 syntaxin-1 binding 3/1840 18/18639 0.166666666666667 1.6883152173913 0.259711965602338 0.709457076767362 GO:0034185 apolipoprotein binding 3/1840 18/18639 0.166666666666667 1.6883152173913 0.259711965602338 0.709457076767362 GO:0050811 GABA receptor binding 3/1840 18/18639 0.166666666666667 1.6883152173913 0.259711965602338 0.709457076767362 GO:0140030 modification-dependent protein binding 20/1840 173/18639 0.115606936416185 1.1710856999246 0.260807688662459 0.710874054053427 GO:1990782 protein tyrosine kinase binding 14/1840 117/18639 0.11965811965812 1.2121237458194 0.26360427496109 0.715363952013779 GO:0016790 thiolester hydrolase activity 6/1840 44/18639 0.136363636363636 1.38134881422925 0.264424758944707 0.715363952013779 GO:0030547 signaling receptor inhibitor activity 6/1840 44/18639 0.136363636363636 1.38134881422925 0.264424758944707 0.715363952013779 GO:0140299 molecular sensor activity 9/1840 71/18639 0.126760563380282 1.28407072872015 0.264777566654451 0.715363952013779 GO:0051018 protein kinase A binding 7/1840 53/18639 0.132075471698113 1.33791017227235 0.265894454836663 0.716809558771923 GO:0035255 ionotropic glutamate receptor binding 4/1840 27/18639 0.148148148148148 1.50072463768116 0.274075486042185 0.737251089091643 GO:0004620 phospholipase activity 13/1840 109/18639 0.119266055045872 1.20815217391304 0.277790839594584 0.745617242659102 GO:0004033 aldo-keto reductase (NADPH) activity 5/1840 36/18639 0.138888888888889 1.40692934782609 0.279935424738081 0.748113759820642 GO:0004869 cysteine-type endopeptidase inhibitor activity 5/1840 36/18639 0.138888888888889 1.40692934782609 0.279935424738081 0.748113759820642 GO:0043130 ubiquitin binding 12/1840 100/18639 0.12 1.21558695652174 0.281504346220394 0.748463584063298 GO:0050661 NADP binding 7/1840 54/18639 0.12962962962963 1.31313405797101 0.281764906849661 0.748463584063298 GO:0008009 chemokine activity 6/1840 45/18639 0.133333333333333 1.35065217391304 0.281888882309554 0.748463584063298 GO:0003730 mRNA 3'-UTR binding 29/1840 262/18639 0.110687022900763 1.12124751078659 0.284797395291948 0.754559980644473 GO:0015245 fatty acid transmembrane transporter activity 3/1840 19/18639 0.157894736842105 1.59945652173913 0.287626104973837 0.758790923614063 GO:0070003 threonine-type peptidase activity 3/1840 19/18639 0.157894736842105 1.59945652173913 0.287626104973837 0.758790923614063 GO:0016791 phosphatase activity 30/1840 273/18639 0.10989010989011 1.11317486860965 0.294442124686205 0.761169328262565 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 4/1840 28/18639 0.142857142857143 1.44712732919255 0.297017029600222 0.761169328262565 GO:0001851 complement component C3b binding 2/1840 11/18639 0.181818181818182 1.84179841897233 0.297177310790823 0.761169328262565 GO:0004523 RNA-DNA hybrid ribonuclease activity 2/1840 11/18639 0.181818181818182 1.84179841897233 0.297177310790823 0.761169328262565 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/1840 11/18639 0.181818181818182 1.84179841897233 0.297177310790823 0.761169328262565 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/1840 11/18639 0.181818181818182 1.84179841897233 0.297177310790823 0.761169328262565 GO:0019107 myristoyltransferase activity 2/1840 11/18639 0.181818181818182 1.84179841897233 0.297177310790823 0.761169328262565 GO:0032050 clathrin heavy chain binding 2/1840 11/18639 0.181818181818182 1.84179841897233 0.297177310790823 0.761169328262565 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/1840 11/18639 0.181818181818182 1.84179841897233 0.297177310790823 0.761169328262565 GO:0034056 estrogen response element binding 2/1840 11/18639 0.181818181818182 1.84179841897233 0.297177310790823 0.761169328262565 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 2/1840 11/18639 0.181818181818182 1.84179841897233 0.297177310790823 0.761169328262565 GO:0034713 type I transforming growth factor beta receptor binding 2/1840 11/18639 0.181818181818182 1.84179841897233 0.297177310790823 0.761169328262565 GO:0043522 leucine zipper domain binding 2/1840 11/18639 0.181818181818182 1.84179841897233 0.297177310790823 0.761169328262565 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/1840 11/18639 0.181818181818182 1.84179841897233 0.297177310790823 0.761169328262565 GO:0098632 cell-cell adhesion mediator activity 7/1840 55/18639 0.127272727272727 1.28925889328063 0.297858236881243 0.761330597173634 GO:0004180 carboxypeptidase activity 6/1840 46/18639 0.130434782608696 1.32129017013232 0.299598145837799 0.76154572333367 GO:0030276 clathrin binding 6/1840 46/18639 0.130434782608696 1.32129017013232 0.299598145837799 0.76154572333367 GO:0022829 wide pore channel activity 5/1840 37/18639 0.135135135135135 1.36890423031727 0.299796814786388 0.76154572333367 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 15/1840 130/18639 0.115384615384615 1.16883361204013 0.301149620890774 0.763408092463855 GO:1901681 sulfur compound binding 30/1840 275/18639 0.109090909090909 1.1050790513834 0.30875217670371 0.781073268375711 GO:0051213 dioxygenase activity 11/1840 93/18639 0.118279569892473 1.19815918653576 0.309968181120247 0.78254262118882 GO:0001216 DNA-binding transcription activator activity 52/1840 491/18639 0.105906313645621 1.07281944567431 0.3157329568372 0.788983056115864 GO:0005326 neurotransmitter transmembrane transporter activity 3/1840 20/18639 0.15 1.51948369565217 0.315746333129412 0.788983056115864 GO:0016004 phospholipase activator activity 3/1840 20/18639 0.15 1.51948369565217 0.315746333129412 0.788983056115864 GO:0016505 peptidase activator activity involved in apoptotic process 3/1840 20/18639 0.15 1.51948369565217 0.315746333129412 0.788983056115864 GO:0030742 GTP-dependent protein binding 3/1840 20/18639 0.15 1.51948369565217 0.315746333129412 0.788983056115864 GO:0004629 phospholipase C activity 4/1840 29/18639 0.137931034482759 1.3972263868066 0.320176758812429 0.788983056115864 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 4/1840 29/18639 0.137931034482759 1.3972263868066 0.320176758812429 0.788983056115864 GO:0043236 laminin binding 4/1840 29/18639 0.137931034482759 1.3972263868066 0.320176758812429 0.788983056115864 GO:0051861 glycolipid binding 4/1840 29/18639 0.137931034482759 1.3972263868066 0.320176758812429 0.788983056115864 GO:0097472 cyclin-dependent protein kinase activity 4/1840 29/18639 0.137931034482759 1.3972263868066 0.320176758812429 0.788983056115864 GO:0106222 lncRNA binding 4/1840 29/18639 0.137931034482759 1.3972263868066 0.320176758812429 0.788983056115864 GO:0019003 GDP binding 9/1840 75/18639 0.12 1.21558695652174 0.320204162384685 0.788983056115864 GO:0051015 actin filament binding 23/1840 209/18639 0.110047846889952 1.11477272727273 0.322700517177176 0.793546980363833 GO:0000340 RNA 7-methylguanosine cap binding 2/1840 12/18639 0.166666666666667 1.6883152173913 0.335102678288453 0.798916994534996 GO:0003720 telomerase activity 2/1840 12/18639 0.166666666666667 1.6883152173913 0.335102678288453 0.798916994534996 GO:0004032 aldose reductase (NADPH) activity 2/1840 12/18639 0.166666666666667 1.6883152173913 0.335102678288453 0.798916994534996 GO:0005049 nuclear export signal receptor activity 2/1840 12/18639 0.166666666666667 1.6883152173913 0.335102678288453 0.798916994534996 GO:0005095 GTPase inhibitor activity 2/1840 12/18639 0.166666666666667 1.6883152173913 0.335102678288453 0.798916994534996 GO:0008504 monoamine transmembrane transporter activity 2/1840 12/18639 0.166666666666667 1.6883152173913 0.335102678288453 0.798916994534996 GO:0016208 AMP binding 2/1840 12/18639 0.166666666666667 1.6883152173913 0.335102678288453 0.798916994534996 GO:0016273 arginine N-methyltransferase activity 2/1840 12/18639 0.166666666666667 1.6883152173913 0.335102678288453 0.798916994534996 GO:0016274 protein-arginine N-methyltransferase activity 2/1840 12/18639 0.166666666666667 1.6883152173913 0.335102678288453 0.798916994534996 GO:0016801 hydrolase activity, acting on ether bonds 2/1840 12/18639 0.166666666666667 1.6883152173913 0.335102678288453 0.798916994534996 GO:0016803 ether hydrolase activity 2/1840 12/18639 0.166666666666667 1.6883152173913 0.335102678288453 0.798916994534996 GO:0016840 carbon-nitrogen lyase activity 2/1840 12/18639 0.166666666666667 1.6883152173913 0.335102678288453 0.798916994534996 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/1840 12/18639 0.166666666666667 1.6883152173913 0.335102678288453 0.798916994534996 GO:0035197 siRNA binding 2/1840 12/18639 0.166666666666667 1.6883152173913 0.335102678288453 0.798916994534996 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/1840 12/18639 0.166666666666667 1.6883152173913 0.335102678288453 0.798916994534996 GO:0008276 protein methyltransferase activity 11/1840 95/18639 0.115789473684211 1.1729347826087 0.33525981020665 0.798916994534996 GO:0050660 flavin adenine dinucleotide binding 10/1840 86/18639 0.116279069767442 1.17789433771486 0.341844595046082 0.810124440717012 GO:0001968 fibronectin binding 4/1840 30/18639 0.133333333333333 1.35065217391304 0.343460265687066 0.810124440717012 GO:0051721 protein phosphatase 2A binding 4/1840 30/18639 0.133333333333333 1.35065217391304 0.343460265687066 0.810124440717012 GO:0010314 phosphatidylinositol-5-phosphate binding 3/1840 21/18639 0.142857142857143 1.44712732919255 0.343908346181004 0.810124440717012 GO:0072542 protein phosphatase activator activity 3/1840 21/18639 0.142857142857143 1.44712732919255 0.343908346181004 0.810124440717012 GO:1904047 S-adenosyl-L-methionine binding 3/1840 21/18639 0.142857142857143 1.44712732919255 0.343908346181004 0.810124440717012 GO:0030145 manganese ion binding 8/1840 68/18639 0.117647058823529 1.19175191815857 0.356060943850664 0.836993711785727 GO:0003823 antigen binding 19/1840 174/18639 0.109195402298851 1.10613755622189 0.356673456726872 0.836993711785727 GO:0061135 endopeptidase regulator activity 20/1840 184/18639 0.108695652173913 1.10107514177694 0.359189247703247 0.840928442788983 GO:0061791 GTPase motor activity 5/1840 40/18639 0.125 1.26623641304348 0.360397904052421 0.840928442788983 GO:1990606 membrane scission GTPase motor activity 5/1840 40/18639 0.125 1.26623641304348 0.360397904052421 0.840928442788983 GO:0005164 tumor necrosis factor receptor binding 4/1840 31/18639 0.129032258064516 1.30708274894811 0.366778388985128 0.841813971154187 GO:0070273 phosphatidylinositol-4-phosphate binding 4/1840 31/18639 0.129032258064516 1.30708274894811 0.366778388985128 0.841813971154187 GO:0015293 symporter activity 16/1840 146/18639 0.10958904109589 1.11012507444908 0.368440710606702 0.841813971154187 GO:0004407 histone deacetylase activity 3/1840 22/18639 0.136363636363636 1.38134881422925 0.371963599900932 0.841813971154187 GO:0008093 cytoskeletal anchor activity 3/1840 22/18639 0.136363636363636 1.38134881422925 0.371963599900932 0.841813971154187 GO:0015377 chloride:monoatomic cation symporter activity 3/1840 22/18639 0.136363636363636 1.38134881422925 0.371963599900932 0.841813971154187 GO:0016881 acid-amino acid ligase activity 3/1840 22/18639 0.136363636363636 1.38134881422925 0.371963599900932 0.841813971154187 GO:0033558 protein lysine deacetylase activity 3/1840 22/18639 0.136363636363636 1.38134881422925 0.371963599900932 0.841813971154187 GO:0032813 tumor necrosis factor receptor superfamily binding 6/1840 50/18639 0.12 1.21558695652174 0.371990711848827 0.841813971154187 GO:0003964 RNA-directed DNA polymerase activity 2/1840 13/18639 0.153846153846154 1.55844481605351 0.372393355745967 0.841813971154187 GO:0005035 death receptor activity 2/1840 13/18639 0.153846153846154 1.55844481605351 0.372393355745967 0.841813971154187 GO:0005172 vascular endothelial growth factor receptor binding 2/1840 13/18639 0.153846153846154 1.55844481605351 0.372393355745967 0.841813971154187 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 2/1840 13/18639 0.153846153846154 1.55844481605351 0.372393355745967 0.841813971154187 GO:0032396 inhibitory MHC class I receptor activity 2/1840 13/18639 0.153846153846154 1.55844481605351 0.372393355745967 0.841813971154187 GO:0043560 insulin receptor substrate binding 2/1840 13/18639 0.153846153846154 1.55844481605351 0.372393355745967 0.841813971154187 GO:0045159 myosin II binding 2/1840 13/18639 0.153846153846154 1.55844481605351 0.372393355745967 0.841813971154187 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/1840 13/18639 0.153846153846154 1.55844481605351 0.372393355745967 0.841813971154187 GO:0004725 protein tyrosine phosphatase activity 11/1840 98/18639 0.112244897959184 1.13702861579414 0.373865566905416 0.843594099684016 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 7/1840 60/18639 0.116666666666667 1.18182065217391 0.380488197715253 0.856967933428138 GO:0031490 chromatin DNA binding 14/1840 128/18639 0.109375 1.10795686141304 0.384582343062734 0.864608479294322 GO:0008028 monocarboxylic acid transmembrane transporter activity 8/1840 70/18639 0.114285714285714 1.15770186335404 0.387009798151453 0.864752756017151 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 50/1840 484/18639 0.103305785123967 1.0464763744161 0.388285079884136 0.864752756017151 GO:0042910 xenobiotic transmembrane transporter activity 4/1840 32/18639 0.125 1.26623641304348 0.390047640464153 0.864752756017151 GO:0043425 bHLH transcription factor binding 4/1840 32/18639 0.125 1.26623641304348 0.390047640464153 0.864752756017151 GO:0051059 NF-kappaB binding 4/1840 32/18639 0.125 1.26623641304348 0.390047640464153 0.864752756017151 GO:0070717 poly-purine tract binding 4/1840 32/18639 0.125 1.26623641304348 0.390047640464153 0.864752756017151 GO:0005048 signal sequence binding 6/1840 51/18639 0.117647058823529 1.19175191815857 0.390261795735013 0.864752756017151 GO:0016597 amino acid binding 6/1840 51/18639 0.117647058823529 1.19175191815857 0.390261795735013 0.864752756017151 GO:0005158 insulin receptor binding 3/1840 23/18639 0.130434782608696 1.32129017013232 0.399779245448679 0.882666721134001 GO:0031681 G-protein beta-subunit binding 3/1840 23/18639 0.130434782608696 1.32129017013232 0.399779245448679 0.882666721134001 GO:0030971 receptor tyrosine kinase binding 9/1840 81/18639 0.111111111111111 1.12554347826087 0.406725878052059 0.886704066583293 GO:0016798 hydrolase activity, acting on glycosyl bonds 14/1840 130/18639 0.107692307692308 1.09091137123746 0.407451032162008 0.886704066583293 GO:0016530 metallochaperone activity 2/1840 14/18639 0.142857142857143 1.44712732919255 0.408805121606583 0.886704066583293 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/1840 14/18639 0.142857142857143 1.44712732919255 0.408805121606583 0.886704066583293 GO:0019763 immunoglobulin receptor activity 2/1840 14/18639 0.142857142857143 1.44712732919255 0.408805121606583 0.886704066583293 GO:0034236 protein kinase A catalytic subunit binding 2/1840 14/18639 0.142857142857143 1.44712732919255 0.408805121606583 0.886704066583293 GO:0042813 Wnt receptor activity 2/1840 14/18639 0.142857142857143 1.44712732919255 0.408805121606583 0.886704066583293 GO:0046030 inositol trisphosphate phosphatase activity 2/1840 14/18639 0.142857142857143 1.44712732919255 0.408805121606583 0.886704066583293 GO:0061665 SUMO ligase activity 2/1840 14/18639 0.142857142857143 1.44712732919255 0.408805121606583 0.886704066583293 GO:0071933 Arp2/3 complex binding 2/1840 14/18639 0.142857142857143 1.44712732919255 0.408805121606583 0.886704066583293 GO:0008514 organic anion transmembrane transporter activity 28/1840 269/18639 0.104089219330855 1.05441247777598 0.412845449874997 0.893071393669845 GO:0071889 14-3-3 protein binding 4/1840 33/18639 0.121212121212121 1.22786561264822 0.413190498694652 0.893071393669845 GO:0004712 protein serine/threonine/tyrosine kinase activity 5/1840 43/18639 0.116279069767442 1.17789433771486 0.421287151622484 0.908493860419541 GO:0008238 exopeptidase activity 11/1840 102/18639 0.107843137254902 1.09243925831202 0.425957373078107 0.908493860419541 GO:0004864 protein phosphatase inhibitor activity 6/1840 53/18639 0.113207547169811 1.14678014766202 0.426727726981471 0.908493860419541 GO:0005315 phosphate transmembrane transporter activity 3/1840 24/18639 0.125 1.26623641304348 0.427237782096238 0.908493860419541 GO:0005540 hyaluronic acid binding 3/1840 24/18639 0.125 1.26623641304348 0.427237782096238 0.908493860419541 GO:0050699 WW domain binding 3/1840 24/18639 0.125 1.26623641304348 0.427237782096238 0.908493860419541 GO:0060229 lipase activator activity 3/1840 24/18639 0.125 1.26623641304348 0.427237782096238 0.908493860419541 GO:0070300 phosphatidic acid binding 3/1840 24/18639 0.125 1.26623641304348 0.427237782096238 0.908493860419541 GO:0070840 dynein complex binding 3/1840 24/18639 0.125 1.26623641304348 0.427237782096238 0.908493860419541 GO:0005200 structural constituent of cytoskeleton 12/1840 112/18639 0.107142857142857 1.08534549689441 0.427700031691018 0.908493860419541 GO:0005507 copper ion binding 7/1840 63/18639 0.111111111111111 1.12554347826087 0.430628147617484 0.913139204586471 GO:0008376 acetylgalactosaminyltransferase activity 4/1840 34/18639 0.117647058823529 1.19175191815857 0.436135586611346 0.915034227561398 GO:0051219 phosphoprotein binding 10/1840 93/18639 0.10752688172043 1.08923562412342 0.437572352469162 0.915034227561398 GO:0001046 core promoter sequence-specific DNA binding 5/1840 44/18639 0.113636363636364 1.15112401185771 0.441397714786302 0.915034227561398 GO:0004559 alpha-mannosidase activity 2/1840 15/18639 0.133333333333333 1.35065217391304 0.444148107209185 0.915034227561398 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/1840 15/18639 0.133333333333333 1.35065217391304 0.444148107209185 0.915034227561398 GO:0004953 icosanoid receptor activity 2/1840 15/18639 0.133333333333333 1.35065217391304 0.444148107209185 0.915034227561398 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/1840 15/18639 0.133333333333333 1.35065217391304 0.444148107209185 0.915034227561398 GO:0010181 FMN binding 2/1840 15/18639 0.133333333333333 1.35065217391304 0.444148107209185 0.915034227561398 GO:0015556 C4-dicarboxylate transmembrane transporter activity 2/1840 15/18639 0.133333333333333 1.35065217391304 0.444148107209185 0.915034227561398 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 2/1840 15/18639 0.133333333333333 1.35065217391304 0.444148107209185 0.915034227561398 GO:0017081 chloride channel regulator activity 2/1840 15/18639 0.133333333333333 1.35065217391304 0.444148107209185 0.915034227561398 GO:0031386 protein tag activity 2/1840 15/18639 0.133333333333333 1.35065217391304 0.444148107209185 0.915034227561398 GO:0042809 nuclear vitamin D receptor binding 2/1840 15/18639 0.133333333333333 1.35065217391304 0.444148107209185 0.915034227561398 GO:0045504 dynein heavy chain binding 2/1840 15/18639 0.133333333333333 1.35065217391304 0.444148107209185 0.915034227561398 GO:0048531 beta-1,3-galactosyltransferase activity 2/1840 15/18639 0.133333333333333 1.35065217391304 0.444148107209185 0.915034227561398 GO:0061578 K63-linked deubiquitinase activity 2/1840 15/18639 0.133333333333333 1.35065217391304 0.444148107209185 0.915034227561398 GO:0141047 molecular tag activity 2/1840 15/18639 0.133333333333333 1.35065217391304 0.444148107209185 0.915034227561398 GO:0051117 ATPase binding 9/1840 84/18639 0.107142857142857 1.08534549689441 0.450288546700053 0.920426586790313 GO:0016410 N-acyltransferase activity 10/1840 94/18639 0.106382978723404 1.07764801110083 0.451264377756789 0.920426586790313 GO:0003707 nuclear steroid receptor activity 3/1840 25/18639 0.12 1.21558695652174 0.454236497377038 0.920426586790313 GO:0005537 D-mannose binding 3/1840 25/18639 0.12 1.21558695652174 0.454236497377038 0.920426586790313 GO:0015296 monoatomic anion:monoatomic cation symporter activity 3/1840 25/18639 0.12 1.21558695652174 0.454236497377038 0.920426586790313 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 3/1840 25/18639 0.12 1.21558695652174 0.454236497377038 0.920426586790313 GO:0017056 structural constituent of nuclear pore 3/1840 25/18639 0.12 1.21558695652174 0.454236497377038 0.920426586790313 GO:0019211 phosphatase activator activity 3/1840 25/18639 0.12 1.21558695652174 0.454236497377038 0.920426586790313 GO:0042974 nuclear retinoic acid receptor binding 3/1840 25/18639 0.12 1.21558695652174 0.454236497377038 0.920426586790313 GO:0120020 cholesterol transfer activity 3/1840 25/18639 0.12 1.21558695652174 0.454236497377038 0.920426586790313 GO:0015631 tubulin binding 39/1840 385/18639 0.101298701298701 1.02614483342744 0.457304657447252 0.925122065640418 GO:0034061 DNA polymerase activity 4/1840 35/18639 0.114285714285714 1.15770186335404 0.458817748179692 0.926661419274395 GO:0000149 SNARE binding 11/1840 106/18639 0.10377358490566 1.05121513535685 0.477910084790998 0.935033664932789 GO:0005149 interleukin-1 receptor binding 2/1840 16/18639 0.125 1.26623641304348 0.478278454935926 0.935033664932789 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1840 16/18639 0.125 1.26623641304348 0.478278454935926 0.935033664932789 GO:0015923 mannosidase activity 2/1840 16/18639 0.125 1.26623641304348 0.478278454935926 0.935033664932789 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/1840 16/18639 0.125 1.26623641304348 0.478278454935926 0.935033664932789 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/1840 16/18639 0.125 1.26623641304348 0.478278454935926 0.935033664932789 GO:0043023 ribosomal large subunit binding 2/1840 16/18639 0.125 1.26623641304348 0.478278454935926 0.935033664932789 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/1840 16/18639 0.125 1.26623641304348 0.478278454935926 0.935033664932789 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/1840 16/18639 0.125 1.26623641304348 0.478278454935926 0.935033664932789 GO:0016407 acetyltransferase activity 10/1840 96/18639 0.104166666666667 1.05519701086957 0.478500060254454 0.935033664932789 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 9/1840 86/18639 0.104651162790698 1.06010490394338 0.479086343595016 0.935033664932789 GO:0004435 phosphatidylinositol phospholipase C activity 3/1840 26/18639 0.115384615384615 1.16883361204013 0.480686752576838 0.935033664932789 GO:0004529 DNA exonuclease activity 3/1840 26/18639 0.115384615384615 1.16883361204013 0.480686752576838 0.935033664932789 GO:0005160 transforming growth factor beta receptor binding 3/1840 26/18639 0.115384615384615 1.16883361204013 0.480686752576838 0.935033664932789 GO:0008157 protein phosphatase 1 binding 3/1840 26/18639 0.115384615384615 1.16883361204013 0.480686752576838 0.935033664932789 GO:0019865 immunoglobulin binding 3/1840 26/18639 0.115384615384615 1.16883361204013 0.480686752576838 0.935033664932789 GO:0030247 polysaccharide binding 3/1840 26/18639 0.115384615384615 1.16883361204013 0.480686752576838 0.935033664932789 GO:0030507 spectrin binding 3/1840 26/18639 0.115384615384615 1.16883361204013 0.480686752576838 0.935033664932789 GO:0070412 R-SMAD binding 3/1840 26/18639 0.115384615384615 1.16883361204013 0.480686752576838 0.935033664932789 GO:0097602 cullin family protein binding 3/1840 26/18639 0.115384615384615 1.16883361204013 0.480686752576838 0.935033664932789 GO:0019212 phosphatase inhibitor activity 6/1840 56/18639 0.107142857142857 1.08534549689441 0.48069159917299 0.935033664932789 GO:0000993 RNA polymerase II complex binding 4/1840 36/18639 0.111111111111111 1.12554347826087 0.481178038609893 0.935033664932789 GO:0044390 ubiquitin-like protein conjugating enzyme binding 4/1840 36/18639 0.111111111111111 1.12554347826087 0.481178038609893 0.935033664932789 GO:0045505 dynein intermediate chain binding 4/1840 36/18639 0.111111111111111 1.12554347826087 0.481178038609893 0.935033664932789 GO:0046982 protein heterodimerization activity 37/1840 369/18639 0.100271002710027 1.01573435843054 0.485797352146822 0.942523366684858 GO:0050840 extracellular matrix binding 7/1840 67/18639 0.104477611940299 1.05834685269306 0.496482335819137 0.961739367498706 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 23/1840 229/18639 0.100436681222707 1.01741266375546 0.497783873958121 0.962746833149771 GO:0001784 phosphotyrosine residue binding 5/1840 47/18639 0.106382978723404 1.07764801110083 0.500531113360289 0.965030252988851 GO:0043495 protein-membrane adaptor activity 5/1840 47/18639 0.106382978723404 1.07764801110083 0.500531113360289 0.965030252988851 GO:0019213 deacetylase activity 4/1840 37/18639 0.108108108108108 1.09512338425382 0.503163641497591 0.967078949025011 GO:0043394 proteoglycan binding 4/1840 37/18639 0.108108108108108 1.09512338425382 0.503163641497591 0.967078949025011 GO:0042626 ATPase-coupled transmembrane transporter activity 10/1840 98/18639 0.102040816326531 1.03366237799468 0.505440052356352 0.9687141934125 GO:0004659 prenyltransferase activity 2/1840 17/18639 0.117647058823529 1.19175191815857 0.511091092303673 0.9687141934125 GO:0015278 intracellularly gated calcium channel activity 2/1840 17/18639 0.117647058823529 1.19175191815857 0.511091092303673 0.9687141934125 GO:0016018 cyclosporin A binding 2/1840 17/18639 0.117647058823529 1.19175191815857 0.511091092303673 0.9687141934125 GO:0016805 dipeptidase activity 2/1840 17/18639 0.117647058823529 1.19175191815857 0.511091092303673 0.9687141934125 GO:0045125 bioactive lipid receptor activity 2/1840 17/18639 0.117647058823529 1.19175191815857 0.511091092303673 0.9687141934125 GO:0046965 nuclear retinoid X receptor binding 2/1840 17/18639 0.117647058823529 1.19175191815857 0.511091092303673 0.9687141934125 GO:0051787 misfolded protein binding 2/1840 17/18639 0.117647058823529 1.19175191815857 0.511091092303673 0.9687141934125 GO:0070402 NADPH binding 2/1840 17/18639 0.117647058823529 1.19175191815857 0.511091092303673 0.9687141934125 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 9/1840 89/18639 0.101123595505618 1.02437103077675 0.521571297680588 0.985545764942461 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 9/1840 89/18639 0.101123595505618 1.02437103077675 0.521571297680588 0.985545764942461 GO:0016298 lipase activity 13/1840 130/18639 0.1 1.01298913043478 0.52360038830295 0.987864744853345 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 4/1840 38/18639 0.105263157894737 1.06630434782609 0.524727725161208 0.988477916511633 GO:0008080 N-acetyltransferase activity 7/1840 69/18639 0.101449275362319 1.02767013232514 0.528525209680895 0.994111539430325 GO:0051959 dynein light intermediate chain binding 3/1840 28/18639 0.107142857142857 1.08534549689441 0.531652696648884 0.996460465015167 GO:0141052 histone H3 demethylase activity 3/1840 28/18639 0.107142857142857 1.08534549689441 0.531652696648884 0.996460465015167 GO:0015459 potassium channel regulator activity 6/1840 59/18639 0.101694915254237 1.03015843773029 0.533009290945613 0.996460465015167 GO:0045309 protein phosphorylated amino acid binding 6/1840 59/18639 0.101694915254237 1.03015843773029 0.533009290945613 0.996460465015167 GO:0140793 histone H2AXY142 phosphatase activity 9/1840 90/18639 0.1 1.01298913043478 0.53548058572375 0.998352003909048 GO:0008201 heparin binding 17/1840 172/18639 0.0988372093023256 1.00121018705763 0.535641781318085 0.998352003909048 GO:0008525 phosphatidylcholine transporter activity 2/1840 18/18639 0.111111111111111 1.12554347826087 0.54251348314134 0.999999979028822 GO:0032393 MHC class I receptor activity 2/1840 18/18639 0.111111111111111 1.12554347826087 0.54251348314134 0.999999979028822 GO:0098641 cadherin binding involved in cell-cell adhesion 2/1840 18/18639 0.111111111111111 1.12554347826087 0.54251348314134 0.999999979028822 GO:0001664 G protein-coupled receptor binding 29/1840 297/18639 0.0976430976430976 0.989113965744401 0.553946324919111 0.999999979028822 GO:0015291 secondary active transmembrane transporter activity 28/1840 287/18639 0.0975609756097561 0.988282078472959 0.555869809728447 0.999999979028822 GO:1901981 phosphatidylinositol phosphate binding 18/1840 185/18639 0.0972972972972973 0.985611045828437 0.562424988695532 0.999999979028822 GO:0004532 RNA exonuclease activity 4/1840 40/18639 0.1 1.01298913043478 0.566432732125565 0.999999979028822 GO:0071855 neuropeptide receptor binding 4/1840 40/18639 0.1 1.01298913043478 0.566432732125565 0.999999979028822 GO:0015026 coreceptor activity 6/1840 61/18639 0.0983606557377049 0.996382751247327 0.566618525970986 0.999999979028822 GO:0003779 actin binding 43/1840 443/18639 0.0970654627539503 0.983262587103739 0.570911511323851 0.999999979028822 GO:0003756 protein disulfide isomerase activity 2/1840 19/18639 0.105263157894737 1.06630434782609 0.572500233513987 0.999999979028822 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/1840 19/18639 0.105263157894737 1.06630434782609 0.572500233513987 0.999999979028822 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/1840 19/18639 0.105263157894737 1.06630434782609 0.572500233513987 0.999999979028822 GO:0031420 alkali metal ion binding 2/1840 19/18639 0.105263157894737 1.06630434782609 0.572500233513987 0.999999979028822 GO:0042577 lipid phosphatase activity 2/1840 19/18639 0.105263157894737 1.06630434782609 0.572500233513987 0.999999979028822 GO:0046624 sphingolipid transporter activity 2/1840 19/18639 0.105263157894737 1.06630434782609 0.572500233513987 0.999999979028822 GO:1990380 K48-linked deubiquitinase activity 2/1840 19/18639 0.105263157894737 1.06630434782609 0.572500233513987 0.999999979028822 GO:0005518 collagen binding 7/1840 72/18639 0.0972222222222222 0.984850543478261 0.575009299291841 0.999999979028822 GO:0003924 GTPase activity 32/1840 331/18639 0.0966767371601208 0.979324839091029 0.577484442423751 0.999999979028822 GO:0032452 histone demethylase activity 3/1840 30/18639 0.1 1.01298913043478 0.579675266478375 0.999999979028822 GO:0048019 receptor antagonist activity 3/1840 30/18639 0.1 1.01298913043478 0.579675266478375 0.999999979028822 GO:0070566 adenylyltransferase activity 3/1840 30/18639 0.1 1.01298913043478 0.579675266478375 0.999999979028822 GO:0140375 immune receptor activity 15/1840 156/18639 0.0961538461538462 0.974028010033445 0.582581402324683 0.999999979028822 GO:0017080 sodium channel regulator activity 4/1840 41/18639 0.0975609756097561 0.988282078472959 0.586507986523084 0.999999979028822 GO:0061650 ubiquitin-like protein conjugating enzyme activity 4/1840 41/18639 0.0975609756097561 0.988282078472959 0.586507986523084 0.999999979028822 GO:0140318 protein transporter activity 4/1840 41/18639 0.0975609756097561 0.988282078472959 0.586507986523084 0.999999979028822 GO:0046943 carboxylic acid transmembrane transporter activity 18/1840 188/18639 0.0957446808510638 0.969883209990749 0.590806228950054 0.999999979028822 GO:0044325 transmembrane transporter binding 13/1840 136/18639 0.0955882352941176 0.968298433503836 0.591289155663902 0.999999979028822 GO:0005342 organic acid transmembrane transporter activity 18/1840 189/18639 0.0952380952380952 0.964751552795031 0.600100773291509 0.999999979028822 GO:0001614 purinergic nucleotide receptor activity 2/1840 20/18639 0.1 1.01298913043478 0.601028444667829 0.999999979028822 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/1840 20/18639 0.1 1.01298913043478 0.601028444667829 0.999999979028822 GO:0015095 magnesium ion transmembrane transporter activity 2/1840 20/18639 0.1 1.01298913043478 0.601028444667829 0.999999979028822 GO:0016408 C-acyltransferase activity 2/1840 20/18639 0.1 1.01298913043478 0.601028444667829 0.999999979028822 GO:0016502 nucleotide receptor activity 2/1840 20/18639 0.1 1.01298913043478 0.601028444667829 0.999999979028822 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/1840 20/18639 0.1 1.01298913043478 0.601028444667829 0.999999979028822 GO:0031418 L-ascorbic acid binding 2/1840 20/18639 0.1 1.01298913043478 0.601028444667829 0.999999979028822 GO:0140939 histone H4 methyltransferase activity 2/1840 20/18639 0.1 1.01298913043478 0.601028444667829 0.999999979028822 GO:0005452 solute:inorganic anion antiporter activity 3/1840 31/18639 0.0967741935483871 0.98031206171108 0.602485646209795 0.999999979028822 GO:0017147 Wnt-protein binding 3/1840 31/18639 0.0967741935483871 0.98031206171108 0.602485646209795 0.999999979028822 GO:0140457 protein demethylase activity 3/1840 31/18639 0.0967741935483871 0.98031206171108 0.602485646209795 0.999999979028822 GO:0035064 methylated histone binding 7/1840 74/18639 0.0945945945945946 0.958232961222092 0.604746105271653 0.999999979028822 GO:0004402 histone acetyltransferase activity 4/1840 42/18639 0.0952380952380952 0.964751552795031 0.606029833782638 0.999999979028822 GO:0019894 kinesin binding 4/1840 42/18639 0.0952380952380952 0.964751552795031 0.606029833782638 0.999999979028822 GO:0048487 beta-tubulin binding 4/1840 42/18639 0.0952380952380952 0.964751552795031 0.606029833782638 0.999999979028822 GO:0005539 glycosaminoglycan binding 23/1840 242/18639 0.0950413223140496 0.96275826446281 0.608457472864685 0.999999979028822 GO:0034212 protein N-acetyltransferase activity 5/1840 53/18639 0.0943396226415094 0.955650123051682 0.610261717102031 0.999999979028822 GO:0019888 protein phosphatase regulator activity 10/1840 107/18639 0.0934579439252336 0.946718813490451 0.620305120908139 0.999999979028822 GO:0008378 galactosyltransferase activity 3/1840 32/18639 0.09375 0.949677309782609 0.624461991631758 0.999999979028822 GO:0022884 macromolecule transmembrane transporter activity 3/1840 32/18639 0.09375 0.949677309782609 0.624461991631758 0.999999979028822 GO:0120015 sterol transfer activity 3/1840 32/18639 0.09375 0.949677309782609 0.624461991631758 0.999999979028822 GO:0008200 ion channel inhibitor activity 4/1840 43/18639 0.0930232558139535 0.942315470171891 0.624977801183679 0.999999979028822 GO:0005123 death receptor binding 2/1840 21/18639 0.0952380952380952 0.964751552795031 0.628093718192758 0.999999979028822 GO:0005248 voltage-gated sodium channel activity 2/1840 21/18639 0.0952380952380952 0.964751552795031 0.628093718192758 0.999999979028822 GO:0035613 RNA stem-loop binding 2/1840 21/18639 0.0952380952380952 0.964751552795031 0.628093718192758 0.999999979028822 GO:0051428 peptide hormone receptor binding 2/1840 21/18639 0.0952380952380952 0.964751552795031 0.628093718192758 0.999999979028822 GO:0120013 lipid transfer activity 6/1840 65/18639 0.0923076923076923 0.935066889632107 0.63006145798343 0.999999979028822 GO:0160215 deacylase activity 6/1840 65/18639 0.0923076923076923 0.935066889632107 0.63006145798343 0.999999979028822 GO:0140034 methylation-dependent protein binding 7/1840 76/18639 0.0921052631578947 0.933016304347826 0.633352168196715 0.999999979028822 GO:0001223 transcription coactivator binding 4/1840 44/18639 0.0909090909090909 0.920899209486166 0.643335809823417 0.999999979028822 GO:0016248 channel inhibitor activity 4/1840 44/18639 0.0909090909090909 0.920899209486166 0.643335809823417 0.999999979028822 GO:0008235 metalloexopeptidase activity 6/1840 66/18639 0.0909090909090909 0.920899209486166 0.64504711260155 0.999999979028822 GO:0000182 rDNA binding 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0004382 GDP phosphatase activity 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0004935 adrenergic receptor activity 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0004955 prostaglandin receptor activity 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0005131 growth hormone receptor binding 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0008140 cAMP response element binding protein binding 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0015187 glycine transmembrane transporter activity 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0015203 polyamine transmembrane transporter activity 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0016783 sulfurtransferase activity 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0016868 intramolecular phosphotransferase activity 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0019911 structural constituent of myelin sheath 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0032052 bile acid binding 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0042975 peroxisome proliferator activated receptor binding 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0047429 nucleoside triphosphate diphosphatase activity 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0050815 phosphoserine residue binding 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0051378 serotonin binding 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0070513 death domain binding 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0070739 protein-glutamic acid ligase activity 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0070740 tubulin-glutamic acid ligase activity 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0071723 lipopeptide binding 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0099122 RNA polymerase II C-terminal domain binding 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:1990763 arrestin family protein binding 1/1840 10/18639 0.1 1.01298913043478 0.646415407456919 0.999999979028822 GO:0004197 cysteine-type endopeptidase activity 8/1840 88/18639 0.0909090909090909 0.920899209486166 0.649750734099629 0.999999979028822 GO:0008237 metallopeptidase activity 17/1840 184/18639 0.0923913043478261 0.935913870510397 0.650113446355667 0.999999979028822 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0032931 histone H3K56 acetyltransferase activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0033691 sialic acid binding 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0034062 5'-3' RNA polymerase activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0043992 histone H3K9 acetyltransferase activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0043993 histone H3K18 acetyltransferase activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0043994 histone H3K23 acetyltransferase activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0043999 histone H2AK5 acetyltransferase activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0044012 histone H2AK9 acetyltransferase activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0044014 histone H2BK5 acetyltransferase activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0044015 histone H2BK12 acetyltransferase activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0044016 histone H3K4 acetyltransferase activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0044017 histone H3K27 acetyltransferase activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0044018 histone H3K36 acetyltransferase activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0046972 histone H4K16 acetyltransferase activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0097747 RNA polymerase activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0140784 metal ion sensor activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0140908 histone H3K122 acetyltransferase activity 2/1840 22/18639 0.0909090909090909 0.920899209486166 0.653706730021941 0.999999979028822 GO:0030695 GTPase regulator activity 46/1840 489/18639 0.0940695296523517 0.952914110429448 0.659050192588206 0.999999979028822 GO:0170055 lipid transmembrane transporter activity 5/1840 56/18639 0.0892857142857143 0.904454580745342 0.659538516910479 0.999999979028822 GO:0141110 transporter inhibitor activity 4/1840 45/18639 0.0888888888888889 0.900434782608696 0.661091857723663 0.999999979028822 GO:0060589 nucleoside-triphosphatase regulator activity 46/1840 490/18639 0.0938775510204082 0.950969387755102 0.664533499572266 0.999999979028822 GO:0051427 hormone receptor binding 3/1840 34/18639 0.0882352941176471 0.893813938618926 0.665858839730061 0.999999979028822 GO:0005506 iron ion binding 14/1840 154/18639 0.0909090909090909 0.920899209486166 0.667468675036171 0.999999979028822 GO:0046332 SMAD binding 7/1840 79/18639 0.0886075949367089 0.897585305448542 0.673960965501122 0.999999979028822 GO:0003887 DNA-directed DNA polymerase activity 2/1840 23/18639 0.0869565217391304 0.88086011342155 0.677890299981299 0.999999979028822 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/1840 23/18639 0.0869565217391304 0.88086011342155 0.677890299981299 0.999999979028822 GO:0004022 alcohol dehydrogenase (NAD+) activity 2/1840 23/18639 0.0869565217391304 0.88086011342155 0.677890299981299 0.999999979028822 GO:0017134 fibroblast growth factor binding 2/1840 23/18639 0.0869565217391304 0.88086011342155 0.677890299981299 0.999999979028822 GO:0043274 phospholipase binding 2/1840 23/18639 0.0869565217391304 0.88086011342155 0.677890299981299 0.999999979028822 GO:0044013 histone H2B acetyltransferase activity 2/1840 23/18639 0.0869565217391304 0.88086011342155 0.677890299981299 0.999999979028822 GO:0070577 lysine-acetylated histone binding 2/1840 23/18639 0.0869565217391304 0.88086011342155 0.677890299981299 0.999999979028822 GO:0140103 catalytic activity, acting on a glycoprotein 2/1840 23/18639 0.0869565217391304 0.88086011342155 0.677890299981299 0.999999979028822 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0000099 sulfur amino acid transmembrane transporter activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0004954 prostanoid receptor activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0005114 type II transforming growth factor beta receptor binding 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0005225 volume-sensitive anion channel activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0008172 S-methyltransferase activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0008199 ferric iron binding 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0008271 secondary active sulfate transmembrane transporter activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0008432 JUN kinase binding 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0008503 benzodiazepine receptor activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0008526 phosphatidylinositol transfer activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0010854 adenylate cyclase regulator activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0016594 glycine binding 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0019206 nucleoside kinase activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0032794 GTPase activating protein binding 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0035252 UDP-xylosyltransferase activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0042285 xylosyltransferase activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0047676 arachidonate-CoA ligase activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0048185 activin binding 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0048407 platelet-derived growth factor binding 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0050998 nitric-oxide synthase binding 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0070697 activin receptor binding 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0140031 phosphorylation-dependent protein binding 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0140537 transcription regulator activator activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0180030 inositol phosphate kinase activity 1/1840 11/18639 0.0909090909090909 0.920899209486166 0.681339217123528 0.999999979028822 GO:0000175 3'-5'-RNA exonuclease activity 3/1840 35/18639 0.0857142857142857 0.868276397515528 0.685268942062908 0.999999979028822 GO:0005154 epidermal growth factor receptor binding 3/1840 35/18639 0.0857142857142857 0.868276397515528 0.685268942062908 0.999999979028822 GO:0043015 gamma-tubulin binding 3/1840 35/18639 0.0857142857142857 0.868276397515528 0.685268942062908 0.999999979028822 GO:0061733 protein-lysine-acetyltransferase activity 4/1840 47/18639 0.0851063829787234 0.862118408880666 0.69476854813526 0.999999979028822 GO:0099095 ligand-gated monoatomic anion channel activity 4/1840 47/18639 0.0851063829787234 0.862118408880666 0.69476854813526 0.999999979028822 GO:0016247 channel regulator activity 15/1840 168/18639 0.0892857142857143 0.904454580745342 0.697359107622914 0.999999979028822 GO:0005126 cytokine receptor binding 25/1840 275/18639 0.0909090909090909 0.920899209486166 0.698492323290563 0.999999979028822 GO:0015149 hexose transmembrane transporter activity 2/1840 24/18639 0.0833333333333333 0.844157608695652 0.700676892516305 0.999999979028822 GO:0030215 semaphorin receptor binding 2/1840 24/18639 0.0833333333333333 0.844157608695652 0.700676892516305 0.999999979028822 GO:0035035 histone acetyltransferase binding 2/1840 24/18639 0.0833333333333333 0.844157608695652 0.700676892516305 0.999999979028822 GO:0043998 histone H2A acetyltransferase activity 2/1840 24/18639 0.0833333333333333 0.844157608695652 0.700676892516305 0.999999979028822 GO:0050431 transforming growth factor beta binding 2/1840 24/18639 0.0833333333333333 0.844157608695652 0.700676892516305 0.999999979028822 GO:0055056 D-glucose transmembrane transporter activity 2/1840 24/18639 0.0833333333333333 0.844157608695652 0.700676892516305 0.999999979028822 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/1840 24/18639 0.0833333333333333 0.844157608695652 0.700676892516305 0.999999979028822 GO:0140033 acetylation-dependent protein binding 2/1840 24/18639 0.0833333333333333 0.844157608695652 0.700676892516305 0.999999979028822 GO:0140612 DNA damage sensor activity 2/1840 24/18639 0.0833333333333333 0.844157608695652 0.700676892516305 0.999999979028822 GO:0004879 nuclear receptor activity 5/1840 59/18639 0.0847457627118644 0.858465364775239 0.704601292896574 0.999999979028822 GO:0070888 E-box binding 5/1840 59/18639 0.0847457627118644 0.858465364775239 0.704601292896574 0.999999979028822 GO:0008017 microtubule binding 25/1840 276/18639 0.0905797101449275 0.917562618147448 0.705326819834825 0.999999979028822 GO:0032266 phosphatidylinositol-3-phosphate binding 4/1840 48/18639 0.0833333333333333 0.844157608695652 0.710682736334923 0.999999979028822 GO:0003995 acyl-CoA dehydrogenase activity 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0004859 phospholipase inhibitor activity 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0005165 neurotrophin receptor binding 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0010853 cyclase activator activity 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0015132 prostaglandin transmembrane transporter activity 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0015166 polyol transmembrane transporter activity 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0017166 vinculin binding 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0031543 peptidyl-proline dioxygenase activity 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0034452 dynactin binding 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0042301 phosphate ion binding 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0070008 serine-type exopeptidase activity 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0070410 co-SMAD binding 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0070679 inositol 1,4,5 trisphosphate binding 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:1990459 transferrin receptor binding 1/1840 12/18639 0.0833333333333333 0.844157608695652 0.712815266108536 0.999999979028822 GO:0141108 transporter regulator activity 15/1840 170/18639 0.0882352941176471 0.893813938618926 0.714548651315656 0.999999979028822 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 5/1840 60/18639 0.0833333333333333 0.844157608695652 0.718659948697869 0.999999979028822 GO:0098531 ligand-modulated transcription factor activity 5/1840 60/18639 0.0833333333333333 0.844157608695652 0.718659948697869 0.999999979028822 GO:0042805 actinin binding 3/1840 37/18639 0.0810810810810811 0.821342538190364 0.721527868122847 0.999999979028822 GO:0000030 mannosyltransferase activity 2/1840 25/18639 0.08 0.810391304347826 0.722106492093632 0.999999979028822 GO:0015645 fatty acid ligase activity 2/1840 25/18639 0.08 0.810391304347826 0.722106492093632 0.999999979028822 GO:0015662 P-type ion transporter activity 2/1840 25/18639 0.08 0.810391304347826 0.722106492093632 0.999999979028822 GO:0017025 TBP-class protein binding 2/1840 25/18639 0.08 0.810391304347826 0.722106492093632 0.999999979028822 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/1840 25/18639 0.08 0.810391304347826 0.722106492093632 0.999999979028822 GO:0120515 fatty acid-CoA ligase activity 2/1840 25/18639 0.08 0.810391304347826 0.722106492093632 0.999999979028822 GO:0140358 P-type transmembrane transporter activity 2/1840 25/18639 0.08 0.810391304347826 0.722106492093632 0.999999979028822 GO:0035254 glutamate receptor binding 4/1840 49/18639 0.0816326530612245 0.826929902395741 0.725981449233872 0.999999979028822 GO:0042379 chemokine receptor binding 6/1840 72/18639 0.0833333333333333 0.844157608695652 0.726902041141918 0.999999979028822 GO:0019208 phosphatase regulator activity 10/1840 117/18639 0.0854700854700855 0.865802675585284 0.729783750445585 0.999999979028822 GO:0030246 carbohydrate binding 25/1840 280/18639 0.0892857142857143 0.904454580745342 0.731764047906454 0.999999979028822 GO:0004867 serine-type endopeptidase inhibitor activity 8/1840 95/18639 0.0842105263157895 0.85304347826087 0.732404384570252 0.999999979028822 GO:0000146 microfilament motor activity 3/1840 38/18639 0.0789473684210526 0.799728260869565 0.738396451805273 0.999999979028822 GO:0048020 CCR chemokine receptor binding 4/1840 50/18639 0.08 0.810391304347826 0.740668421144368 0.999999979028822 GO:0004535 poly(A)-specific ribonuclease activity 1/1840 13/18639 0.0769230769230769 0.779222408026756 0.741183758638749 0.999999979028822 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/1840 13/18639 0.0769230769230769 0.779222408026756 0.741183758638749 0.999999979028822 GO:0008253 5'-nucleotidase activity 1/1840 13/18639 0.0769230769230769 0.779222408026756 0.741183758638749 0.999999979028822 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/1840 13/18639 0.0769230769230769 0.779222408026756 0.741183758638749 0.999999979028822 GO:0019855 calcium channel inhibitor activity 1/1840 13/18639 0.0769230769230769 0.779222408026756 0.741183758638749 0.999999979028822 GO:0030955 potassium ion binding 1/1840 13/18639 0.0769230769230769 0.779222408026756 0.741183758638749 0.999999979028822 GO:0039706 co-receptor binding 1/1840 13/18639 0.0769230769230769 0.779222408026756 0.741183758638749 0.999999979028822 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/1840 13/18639 0.0769230769230769 0.779222408026756 0.741183758638749 0.999999979028822 GO:0046974 histone H3K9 methyltransferase activity 1/1840 13/18639 0.0769230769230769 0.779222408026756 0.741183758638749 0.999999979028822 GO:0070700 BMP receptor binding 1/1840 13/18639 0.0769230769230769 0.779222408026756 0.741183758638749 0.999999979028822 GO:0071714 icosanoid transmembrane transporter activity 1/1840 13/18639 0.0769230769230769 0.779222408026756 0.741183758638749 0.999999979028822 GO:0071837 HMG box domain binding 1/1840 13/18639 0.0769230769230769 0.779222408026756 0.741183758638749 0.999999979028822 GO:0089720 caspase binding 1/1840 13/18639 0.0769230769230769 0.779222408026756 0.741183758638749 0.999999979028822 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/1840 13/18639 0.0769230769230769 0.779222408026756 0.741183758638749 0.999999979028822 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1840 13/18639 0.0769230769230769 0.779222408026756 0.741183758638749 0.999999979028822 GO:0015145 monosaccharide transmembrane transporter activity 2/1840 26/18639 0.0769230769230769 0.779222408026756 0.742224803720032 0.999999979028822 GO:0120014 phospholipid transfer activity 2/1840 26/18639 0.0769230769230769 0.779222408026756 0.742224803720032 0.999999979028822 GO:0005096 GTPase activator activity 24/1840 271/18639 0.0885608856088561 0.897112145034494 0.742880301289105 0.999999979028822 GO:0051020 GTPase binding 28/1840 315/18639 0.0888888888888889 0.900434782608696 0.749170040291398 0.999999979028822 GO:0005021 vascular endothelial growth factor receptor activity 4/1840 51/18639 0.0784313725490196 0.794501278772378 0.754749663449444 0.999999979028822 GO:1901682 sulfur compound transmembrane transporter activity 5/1840 63/18639 0.0793650793650794 0.803959627329192 0.757941193707021 0.999999979028822 GO:0008266 poly(U) RNA binding 2/1840 27/18639 0.0740740740740741 0.75036231884058 0.761081735146141 0.999999979028822 GO:0008320 protein transmembrane transporter activity 2/1840 27/18639 0.0740740740740741 0.75036231884058 0.761081735146141 0.999999979028822 GO:0016405 CoA-ligase activity 2/1840 27/18639 0.0740740740740741 0.75036231884058 0.761081735146141 0.999999979028822 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/1840 27/18639 0.0740740740740741 0.75036231884058 0.761081735146141 0.999999979028822 GO:0005545 1-phosphatidylinositol binding 1/1840 14/18639 0.0714285714285714 0.723563664596273 0.766751346102762 0.999999979028822 GO:0008392 arachidonate epoxygenase activity 1/1840 14/18639 0.0714285714285714 0.723563664596273 0.766751346102762 0.999999979028822 GO:0008494 translation activator activity 1/1840 14/18639 0.0714285714285714 0.723563664596273 0.766751346102762 0.999999979028822 GO:0008559 ABC-type xenobiotic transporter activity 1/1840 14/18639 0.0714285714285714 0.723563664596273 0.766751346102762 0.999999979028822 GO:0019992 diacylglycerol binding 1/1840 14/18639 0.0714285714285714 0.723563664596273 0.766751346102762 0.999999979028822 GO:0032036 myosin heavy chain binding 1/1840 14/18639 0.0714285714285714 0.723563664596273 0.766751346102762 0.999999979028822 GO:0032454 histone H3K9 demethylase activity 1/1840 14/18639 0.0714285714285714 0.723563664596273 0.766751346102762 0.999999979028822 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/1840 14/18639 0.0714285714285714 0.723563664596273 0.766751346102762 0.999999979028822 GO:0043176 amine binding 1/1840 14/18639 0.0714285714285714 0.723563664596273 0.766751346102762 0.999999979028822 GO:0044548 S100 protein binding 1/1840 14/18639 0.0714285714285714 0.723563664596273 0.766751346102762 0.999999979028822 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/1840 14/18639 0.0714285714285714 0.723563664596273 0.766751346102762 0.999999979028822 GO:1901474 azole transmembrane transporter activity 1/1840 14/18639 0.0714285714285714 0.723563664596273 0.766751346102762 0.999999979028822 GO:0032451 demethylase activity 3/1840 40/18639 0.075 0.759741847826087 0.76968785272408 0.999999979028822 GO:0050997 quaternary ammonium group binding 3/1840 40/18639 0.075 0.759741847826087 0.76968785272408 0.999999979028822 GO:0071949 FAD binding 3/1840 40/18639 0.075 0.759741847826087 0.76968785272408 0.999999979028822 GO:0004222 metalloendopeptidase activity 9/1840 110/18639 0.0818181818181818 0.828809288537549 0.76971229173108 0.999999979028822 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 10/1840 122/18639 0.0819672131147541 0.830318959372773 0.775904003625806 0.999999979028822 GO:0036408 histone H3K14 acetyltransferase activity 2/1840 28/18639 0.0714285714285714 0.723563664596273 0.778730122722853 0.999999979028822 GO:0045499 chemorepellent activity 2/1840 28/18639 0.0714285714285714 0.723563664596273 0.778730122722853 0.999999979028822 GO:0051019 mitogen-activated protein kinase binding 2/1840 28/18639 0.0714285714285714 0.723563664596273 0.778730122722853 0.999999979028822 GO:0051119 sugar transmembrane transporter activity 2/1840 28/18639 0.0714285714285714 0.723563664596273 0.778730122722853 0.999999979028822 GO:0051393 alpha-actinin binding 2/1840 28/18639 0.0714285714285714 0.723563664596273 0.778730122722853 0.999999979028822 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/1840 41/18639 0.0731707317073171 0.741211558854719 0.784149421108369 0.999999979028822 GO:0015175 neutral L-amino acid transmembrane transporter activity 3/1840 41/18639 0.0731707317073171 0.741211558854719 0.784149421108369 0.999999979028822 GO:0001217 DNA-binding transcription repressor activity 24/1840 278/18639 0.0863309352517986 0.87452299030341 0.785096548226429 0.999999979028822 GO:0004089 carbonate dehydratase activity 1/1840 15/18639 0.0666666666666667 0.675326086956522 0.78979443459516 0.999999979028822 GO:0004467 long-chain fatty acid-CoA ligase activity 1/1840 15/18639 0.0666666666666667 0.675326086956522 0.78979443459516 0.999999979028822 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/1840 15/18639 0.0666666666666667 0.675326086956522 0.78979443459516 0.999999979028822 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/1840 15/18639 0.0666666666666667 0.675326086956522 0.78979443459516 0.999999979028822 GO:0008252 nucleotidase activity 1/1840 15/18639 0.0666666666666667 0.675326086956522 0.78979443459516 0.999999979028822 GO:0015116 sulfate transmembrane transporter activity 1/1840 15/18639 0.0666666666666667 0.675326086956522 0.78979443459516 0.999999979028822 GO:0031005 filamin binding 1/1840 15/18639 0.0666666666666667 0.675326086956522 0.78979443459516 0.999999979028822 GO:0033130 acetylcholine receptor binding 1/1840 15/18639 0.0666666666666667 0.675326086956522 0.78979443459516 0.999999979028822 GO:0047372 monoacylglycerol lipase activity 1/1840 15/18639 0.0666666666666667 0.675326086956522 0.78979443459516 0.999999979028822 GO:0050700 CARD domain binding 1/1840 15/18639 0.0666666666666667 0.675326086956522 0.78979443459516 0.999999979028822 GO:0051371 muscle alpha-actinin binding 1/1840 15/18639 0.0666666666666667 0.675326086956522 0.78979443459516 0.999999979028822 GO:0120283 protein serine/threonine kinase binding 1/1840 15/18639 0.0666666666666667 0.675326086956522 0.78979443459516 0.999999979028822 GO:0140161 monocarboxylate:sodium symporter activity 1/1840 15/18639 0.0666666666666667 0.675326086956522 0.78979443459516 0.999999979028822 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 23/1840 268/18639 0.0858208955223881 0.869356343283582 0.790263572877531 0.999999979028822 GO:0010484 histone H3 acetyltransferase activity 2/1840 29/18639 0.0689655172413793 0.698613193403298 0.795224667635713 0.999999979028822 GO:0035250 UDP-galactosyltransferase activity 2/1840 29/18639 0.0689655172413793 0.698613193403298 0.795224667635713 0.999999979028822 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/1840 29/18639 0.0689655172413793 0.698613193403298 0.795224667635713 0.999999979028822 GO:0099604 ligand-gated calcium channel activity 2/1840 29/18639 0.0689655172413793 0.698613193403298 0.795224667635713 0.999999979028822 GO:0016779 nucleotidyltransferase activity 11/1840 136/18639 0.0808823529411765 0.819329443734015 0.79776796611729 0.999999979028822 GO:0042054 histone methyltransferase activity 5/1840 67/18639 0.0746268656716418 0.755962037637897 0.803701622045884 0.999999979028822 GO:0015370 solute:sodium symporter activity 6/1840 79/18639 0.0759493670886076 0.769358833241607 0.804429261243972 0.999999979028822 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 7/1840 91/18639 0.0769230769230769 0.779222408026756 0.806452176354462 0.999999979028822 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/1840 16/18639 0.0625 0.633118206521739 0.810562166572442 0.999999979028822 GO:0004708 MAP kinase kinase activity 1/1840 16/18639 0.0625 0.633118206521739 0.810562166572442 0.999999979028822 GO:0008142 oxysterol binding 1/1840 16/18639 0.0625 0.633118206521739 0.810562166572442 0.999999979028822 GO:0008391 arachidonate monooxygenase activity 1/1840 16/18639 0.0625 0.633118206521739 0.810562166572442 0.999999979028822 GO:0015378 sodium:chloride symporter activity 1/1840 16/18639 0.0625 0.633118206521739 0.810562166572442 0.999999979028822 GO:0015385 sodium:proton antiporter activity 1/1840 16/18639 0.0625 0.633118206521739 0.810562166572442 0.999999979028822 GO:0015562 efflux transmembrane transporter activity 1/1840 16/18639 0.0625 0.633118206521739 0.810562166572442 0.999999979028822 GO:0022858 alanine transmembrane transporter activity 1/1840 16/18639 0.0625 0.633118206521739 0.810562166572442 0.999999979028822 GO:0034450 ubiquitin-ubiquitin ligase activity 1/1840 16/18639 0.0625 0.633118206521739 0.810562166572442 0.999999979028822 GO:0055102 lipase inhibitor activity 1/1840 16/18639 0.0625 0.633118206521739 0.810562166572442 0.999999979028822 GO:0070411 I-SMAD binding 1/1840 16/18639 0.0625 0.633118206521739 0.810562166572442 0.999999979028822 GO:0140328 floppase activity 1/1840 16/18639 0.0625 0.633118206521739 0.810562166572442 0.999999979028822 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/1840 30/18639 0.0666666666666667 0.675326086956522 0.810621053432665 0.999999979028822 GO:0031210 phosphatidylcholine binding 2/1840 30/18639 0.0666666666666667 0.675326086956522 0.810621053432665 0.999999979028822 GO:0031624 ubiquitin conjugating enzyme binding 2/1840 30/18639 0.0666666666666667 0.675326086956522 0.810621053432665 0.999999979028822 GO:0033612 receptor serine/threonine kinase binding 2/1840 30/18639 0.0666666666666667 0.675326086956522 0.810621053432665 0.999999979028822 GO:0043995 histone H4K5 acetyltransferase activity 2/1840 30/18639 0.0666666666666667 0.675326086956522 0.810621053432665 0.999999979028822 GO:0043996 histone H4K8 acetyltransferase activity 2/1840 30/18639 0.0666666666666667 0.675326086956522 0.810621053432665 0.999999979028822 GO:0043997 histone H4K12 acetyltransferase activity 2/1840 30/18639 0.0666666666666667 0.675326086956522 0.810621053432665 0.999999979028822 GO:0008375 acetylglucosaminyltransferase activity 3/1840 43/18639 0.0697674418604651 0.706736602628918 0.810816412323887 0.999999979028822 GO:0017124 SH3 domain binding 9/1840 115/18639 0.0782608695652174 0.792774102079395 0.81254503638798 0.999999979028822 GO:0004866 endopeptidase inhibitor activity 13/1840 161/18639 0.0807453416149068 0.817941533891439 0.814547951841884 0.999999979028822 GO:0005178 integrin binding 13/1840 161/18639 0.0807453416149068 0.817941533891439 0.814547951841884 0.999999979028822 GO:0035091 phosphatidylinositol binding 24/1840 284/18639 0.0845070422535211 0.856047152480098 0.817354675730851 0.999999979028822 GO:0140767 enzyme-substrate adaptor activity 11/1840 139/18639 0.079136690647482 0.801646074444792 0.819880145502193 0.999999979028822 GO:0015101 organic cation transmembrane transporter activity 6/1840 81/18639 0.0740740740740741 0.75036231884058 0.823126329830891 0.999999979028822 GO:0005085 guanyl-nucleotide exchange factor activity 19/1840 230/18639 0.0826086956521739 0.836817107750473 0.824471568478825 0.999999979028822 GO:0016878 acid-thiol ligase activity 2/1840 31/18639 0.0645161290322581 0.653541374474053 0.824975219448035 0.999999979028822 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/1840 17/18639 0.0588235294117647 0.595875959079284 0.829279108714241 0.999999979028822 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/1840 17/18639 0.0588235294117647 0.595875959079284 0.829279108714241 0.999999979028822 GO:0008569 minus-end-directed microtubule motor activity 1/1840 17/18639 0.0588235294117647 0.595875959079284 0.829279108714241 0.999999979028822 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/1840 17/18639 0.0588235294117647 0.595875959079284 0.829279108714241 0.999999979028822 GO:0017110 nucleoside diphosphate phosphatase activity 1/1840 17/18639 0.0588235294117647 0.595875959079284 0.829279108714241 0.999999979028822 GO:0019198 transmembrane receptor protein phosphatase activity 1/1840 17/18639 0.0588235294117647 0.595875959079284 0.829279108714241 0.999999979028822 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/1840 17/18639 0.0588235294117647 0.595875959079284 0.829279108714241 0.999999979028822 GO:0030548 acetylcholine receptor regulator activity 1/1840 17/18639 0.0588235294117647 0.595875959079284 0.829279108714241 0.999999979028822 GO:0036041 long-chain fatty acid binding 1/1840 17/18639 0.0588235294117647 0.595875959079284 0.829279108714241 0.999999979028822 GO:0038191 neuropilin binding 1/1840 17/18639 0.0588235294117647 0.595875959079284 0.829279108714241 0.999999979028822 GO:0045236 CXCR chemokine receptor binding 1/1840 17/18639 0.0588235294117647 0.595875959079284 0.829279108714241 0.999999979028822 GO:0003774 cytoskeletal motor activity 12/1840 153/18639 0.0784313725490196 0.794501278772378 0.836726303452616 0.999999979028822 GO:0005543 phospholipid binding 43/1840 497/18639 0.0865191146881288 0.876429227539148 0.841563425351218 0.999999979028822 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 3/1840 46/18639 0.0652173913043478 0.660645085066162 0.84555289620922 0.999999979028822 GO:0015280 ligand-gated sodium channel activity 1/1840 18/18639 0.0555555555555556 0.562771739130435 0.846147674924411 0.999999979028822 GO:0015373 monoatomic anion:sodium symporter activity 1/1840 18/18639 0.0555555555555556 0.562771739130435 0.846147674924411 0.999999979028822 GO:0022851 GABA-gated chloride ion channel activity 1/1840 18/18639 0.0555555555555556 0.562771739130435 0.846147674924411 0.999999979028822 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/1840 18/18639 0.0555555555555556 0.562771739130435 0.846147674924411 0.999999979028822 GO:0070064 proline-rich region binding 1/1840 18/18639 0.0555555555555556 0.562771739130435 0.846147674924411 0.999999979028822 GO:0099602 neurotransmitter receptor regulator activity 1/1840 18/18639 0.0555555555555556 0.562771739130435 0.846147674924411 0.999999979028822 GO:0001786 phosphatidylserine binding 4/1840 59/18639 0.0677966101694915 0.686772291820192 0.846872439295307 0.999999979028822 GO:0005319 lipid transporter activity 14/1840 178/18639 0.0786516853932584 0.796733023937469 0.848930361863911 0.999999979028822 GO:0030296 protein tyrosine kinase activator activity 2/1840 33/18639 0.0606060606060606 0.613932806324111 0.850778485842905 0.999999979028822 GO:0140359 ABC-type transporter activity 3/1840 47/18639 0.0638297872340425 0.6465888066605 0.855833647214263 0.999999979028822 GO:0140938 histone H3 methyltransferase activity 3/1840 47/18639 0.0638297872340425 0.6465888066605 0.855833647214263 0.999999979028822 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/1840 60/18639 0.0666666666666667 0.675326086956522 0.856030474337982 0.999999979028822 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/1840 19/18639 0.0526315789473684 0.533152173913043 0.861350310558324 0.999999979028822 GO:0004890 GABA-A receptor activity 1/1840 19/18639 0.0526315789473684 0.533152173913043 0.861350310558324 0.999999979028822 GO:0005229 intracellularly calcium-gated chloride channel activity 1/1840 19/18639 0.0526315789473684 0.533152173913043 0.861350310558324 0.999999979028822 GO:0008381 mechanosensitive monoatomic ion channel activity 1/1840 19/18639 0.0526315789473684 0.533152173913043 0.861350310558324 0.999999979028822 GO:0008574 plus-end-directed microtubule motor activity 1/1840 19/18639 0.0526315789473684 0.533152173913043 0.861350310558324 0.999999979028822 GO:0022840 leak channel activity 1/1840 19/18639 0.0526315789473684 0.533152173913043 0.861350310558324 0.999999979028822 GO:0022842 narrow pore channel activity 1/1840 19/18639 0.0526315789473684 0.533152173913043 0.861350310558324 0.999999979028822 GO:0030506 ankyrin binding 1/1840 19/18639 0.0526315789473684 0.533152173913043 0.861350310558324 0.999999979028822 GO:0043395 heparan sulfate proteoglycan binding 1/1840 19/18639 0.0526315789473684 0.533152173913043 0.861350310558324 0.999999979028822 GO:0141147 intracellularly calcium-gated channel activity 1/1840 19/18639 0.0526315789473684 0.533152173913043 0.861350310558324 0.999999979028822 GO:0008170 N-methyltransferase activity 7/1840 98/18639 0.0714285714285714 0.723563664596273 0.862058710433751 0.999999979028822 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/1840 34/18639 0.0588235294117647 0.595875959079284 0.862335963724958 0.999999979028822 GO:0052866 phosphatidylinositol phosphate phosphatase activity 2/1840 34/18639 0.0588235294117647 0.595875959079284 0.862335963724958 0.999999979028822 GO:0030414 peptidase inhibitor activity 13/1840 169/18639 0.0769230769230769 0.779222408026756 0.862653884783362 0.999999979028822 GO:0031267 small GTPase binding 23/1840 283/18639 0.0812720848056537 0.82327738515901 0.864000309857593 0.999999979028822 GO:0015297 antiporter activity 10/1840 135/18639 0.0740740740740741 0.75036231884058 0.868788879500692 0.999999979028822 GO:0015179 L-amino acid transmembrane transporter activity 4/1840 62/18639 0.0645161290322581 0.653541374474053 0.87295166210517 0.999999979028822 GO:0005343 organic acid:sodium symporter activity 2/1840 35/18639 0.0571428571428571 0.578850931677019 0.873067298371142 0.999999979028822 GO:0010485 histone H4 acetyltransferase activity 2/1840 35/18639 0.0571428571428571 0.578850931677019 0.873067298371142 0.999999979028822 GO:0061631 ubiquitin conjugating enzyme activity 2/1840 35/18639 0.0571428571428571 0.578850931677019 0.873067298371142 0.999999979028822 GO:0140566 histone reader activity 2/1840 35/18639 0.0571428571428571 0.578850931677019 0.873067298371142 0.999999979028822 GO:0001222 transcription corepressor binding 3/1840 49/18639 0.0612244897959184 0.620197426796806 0.874610087130502 0.999999979028822 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/1840 20/18639 0.05 0.506494565217391 0.875051461394665 0.999999979028822 GO:0010851 cyclase regulator activity 1/1840 20/18639 0.05 0.506494565217391 0.875051461394665 0.999999979028822 GO:0030627 pre-mRNA 5'-splice site binding 1/1840 20/18639 0.05 0.506494565217391 0.875051461394665 0.999999979028822 GO:0140664 ATP-dependent DNA damage sensor activity 1/1840 20/18639 0.05 0.506494565217391 0.875051461394665 0.999999979028822 GO:0099106 ion channel regulator activity 12/1840 160/18639 0.075 0.759741847826087 0.876489036171346 0.999999979028822 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 2/1840 36/18639 0.0555555555555556 0.562771739130435 0.88302286530129 0.999999979028822 GO:0005484 SNAP receptor activity 2/1840 36/18639 0.0555555555555556 0.562771739130435 0.88302286530129 0.999999979028822 GO:0008373 sialyltransferase activity 1/1840 21/18639 0.0476190476190476 0.482375776397515 0.887399348554761 0.999999979028822 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/1840 21/18639 0.0476190476190476 0.482375776397515 0.887399348554761 0.999999979028822 GO:0015125 bile acid transmembrane transporter activity 1/1840 21/18639 0.0476190476190476 0.482375776397515 0.887399348554761 0.999999979028822 GO:0015174 basic amino acid transmembrane transporter activity 1/1840 21/18639 0.0476190476190476 0.482375776397515 0.887399348554761 0.999999979028822 GO:0036122 BMP binding 1/1840 21/18639 0.0476190476190476 0.482375776397515 0.887399348554761 0.999999979028822 GO:0061891 calcium ion sensor activity 1/1840 21/18639 0.0476190476190476 0.482375776397515 0.887399348554761 0.999999979028822 GO:0005272 sodium channel activity 3/1840 51/18639 0.0588235294117647 0.595875959079284 0.891185173404841 0.999999979028822 GO:0101005 deubiquitinase activity 8/1840 115/18639 0.0695652173913043 0.70468809073724 0.891380903614864 0.999999979028822 GO:0030551 cyclic nucleotide binding 2/1840 37/18639 0.0540540540540541 0.54756169212691 0.892251150854344 0.999999979028822 GO:0008234 cysteine-type peptidase activity 14/1840 187/18639 0.0748663101604278 0.758387584282725 0.892945018209973 0.999999979028822 GO:0005125 cytokine activity 18/1840 234/18639 0.0769230769230769 0.779222408026756 0.895011665633729 0.999999979028822 GO:0005243 gap junction channel activity 1/1840 22/18639 0.0454545454545455 0.460449604743083 0.898527568484895 0.999999979028822 GO:0008970 phospholipase A1 activity 1/1840 22/18639 0.0454545454545455 0.460449604743083 0.898527568484895 0.999999979028822 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/1840 22/18639 0.0454545454545455 0.460449604743083 0.898527568484895 0.999999979028822 GO:0031683 G-protein beta/gamma-subunit complex binding 1/1840 22/18639 0.0454545454545455 0.460449604743083 0.898527568484895 0.999999979028822 GO:0030159 signaling receptor complex adaptor activity 3/1840 52/18639 0.0576923076923077 0.584416806020067 0.898712845066818 0.999999979028822 GO:0015103 inorganic anion transmembrane transporter activity 12/1840 165/18639 0.0727272727272727 0.736719367588933 0.899825770163282 0.999999979028822 GO:0061659 ubiquitin-like protein ligase activity 30/1840 372/18639 0.0806451612903226 0.816926718092567 0.900476594325426 0.999999979028822 GO:0005246 calcium channel regulator activity 3/1840 53/18639 0.0566037735849057 0.573390073831009 0.905767885705524 0.999999979028822 GO:0005544 calcium-dependent phospholipid binding 3/1840 53/18639 0.0566037735849057 0.573390073831009 0.905767885705524 0.999999979028822 GO:0008146 sulfotransferase activity 3/1840 53/18639 0.0566037735849057 0.573390073831009 0.905767885705524 0.999999979028822 GO:0016251 RNA polymerase II general transcription initiation factor activity 3/1840 53/18639 0.0566037735849057 0.573390073831009 0.905767885705524 0.999999979028822 GO:0017046 peptide hormone binding 3/1840 53/18639 0.0566037735849057 0.573390073831009 0.905767885705524 0.999999979028822 GO:0048306 calcium-dependent protein binding 5/1840 80/18639 0.0625 0.633118206521739 0.906644892028263 0.999999979028822 GO:0016500 protein-hormone receptor activity 4/1840 67/18639 0.0597014925373134 0.604769630110318 0.907914711844949 0.999999979028822 GO:0005212 structural constituent of eye lens 1/1840 23/18639 0.0434782608695652 0.440430056710775 0.908556535235059 0.999999979028822 GO:0016849 phosphorus-oxygen lyase activity 1/1840 23/18639 0.0434782608695652 0.440430056710775 0.908556535235059 0.999999979028822 GO:0016917 GABA receptor activity 1/1840 23/18639 0.0434782608695652 0.440430056710775 0.908556535235059 0.999999979028822 GO:0099186 structural constituent of postsynapse 1/1840 23/18639 0.0434782608695652 0.440430056710775 0.908556535235059 0.999999979028822 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/1840 23/18639 0.0434782608695652 0.440430056710775 0.908556535235059 0.999999979028822 GO:0008013 beta-catenin binding 7/1840 106/18639 0.0660377358490566 0.668955086136177 0.908852587243413 0.999999979028822 GO:0019955 cytokine binding 10/1840 144/18639 0.0694444444444444 0.703464673913043 0.912767169737046 0.999999979028822 GO:0003777 microtubule motor activity 4/1840 68/18639 0.0588235294117647 0.595875959079284 0.913784133120516 0.999999979028822 GO:0140223 general transcription initiation factor activity 4/1840 68/18639 0.0588235294117647 0.595875959079284 0.913784133120516 0.999999979028822 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 13/1840 181/18639 0.0718232044198895 0.727561253903435 0.915775698711635 0.999999979028822 GO:0015144 carbohydrate transmembrane transporter activity 2/1840 40/18639 0.05 0.506494565217391 0.916026650536589 0.999999979028822 GO:0030552 cAMP binding 1/1840 24/18639 0.0416666666666667 0.422078804347826 0.917594780570657 0.999999979028822 GO:0004896 cytokine receptor activity 6/1840 96/18639 0.0625 0.633118206521739 0.921830393861849 0.999999979028822 GO:0030165 PDZ domain binding 5/1840 83/18639 0.0602409638554217 0.610234415924568 0.922282279477045 0.999999979028822 GO:0008227 G protein-coupled amine receptor activity 2/1840 41/18639 0.0487804878048781 0.494141039236479 0.922789585379062 0.999999979028822 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/1840 41/18639 0.0487804878048781 0.494141039236479 0.922789585379062 0.999999979028822 GO:0016782 transferase activity, transferring sulphur-containing groups 4/1840 70/18639 0.0571428571428571 0.578850931677019 0.924530234132831 0.999999979028822 GO:0005251 delayed rectifier potassium channel activity 1/1840 25/18639 0.04 0.405195652173913 0.925740125923866 0.999999979028822 GO:0047617 fatty acyl-CoA hydrolase activity 1/1840 25/18639 0.04 0.405195652173913 0.925740125923866 0.999999979028822 GO:0008307 structural constituent of muscle 2/1840 42/18639 0.0476190476190476 0.482375776397515 0.929036518256729 0.999999979028822 GO:0019838 growth factor binding 9/1840 136/18639 0.0661764705882353 0.670360453964194 0.929389203087317 0.999999979028822 GO:0001637 G protein-coupled chemoattractant receptor activity 1/1840 26/18639 0.0384615384615385 0.389611204013378 0.933080738812019 0.999999979028822 GO:0004950 chemokine receptor activity 1/1840 26/18639 0.0384615384615385 0.389611204013378 0.933080738812019 0.999999979028822 GO:0005227 calcium-activated cation channel activity 1/1840 26/18639 0.0384615384615385 0.389611204013378 0.933080738812019 0.999999979028822 GO:0016289 acyl-CoA hydrolase activity 1/1840 26/18639 0.0384615384615385 0.389611204013378 0.933080738812019 0.999999979028822 GO:0043548 phosphatidylinositol 3-kinase binding 1/1840 26/18639 0.0384615384615385 0.389611204013378 0.933080738812019 0.999999979028822 GO:0051139 metal cation:proton antiporter activity 1/1840 26/18639 0.0384615384615385 0.389611204013378 0.933080738812019 0.999999979028822 GO:0052742 phosphatidylinositol kinase activity 1/1840 26/18639 0.0384615384615385 0.389611204013378 0.933080738812019 0.999999979028822 GO:0061630 ubiquitin protein ligase activity 27/1840 353/18639 0.0764872521246459 0.77480755019091 0.937960647654234 0.999999979028822 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/1840 27/18639 0.037037037037037 0.37518115942029 0.939696085106861 0.999999979028822 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/1840 27/18639 0.037037037037037 0.37518115942029 0.939696085106861 0.999999979028822 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/1840 44/18639 0.0454545454545455 0.460449604743083 0.940123936603756 0.999999979028822 GO:0019783 ubiquitin-like protein peptidase activity 8/1840 127/18639 0.062992125984252 0.638103389250257 0.941629108331983 0.999999979028822 GO:0005242 inward rectifier potassium channel activity 1/1840 28/18639 0.0357142857142857 0.361781832298137 0.945657787417379 0.999999979028822 GO:0046875 ephrin receptor binding 1/1840 28/18639 0.0357142857142857 0.361781832298137 0.945657787417379 0.999999979028822 GO:0050698 proteoglycan sulfotransferase activity 1/1840 28/18639 0.0357142857142857 0.361781832298137 0.945657787417379 0.999999979028822 GO:0004181 metallocarboxypeptidase activity 1/1840 29/18639 0.0344827586206897 0.349306596701649 0.951030398838153 0.999999979028822 GO:0016417 S-acyltransferase activity 1/1840 29/18639 0.0344827586206897 0.349306596701649 0.951030398838153 0.999999979028822 GO:0016757 glycosyltransferase activity 19/1840 267/18639 0.0711610486891386 0.720853688324377 0.953192641212722 0.999999979028822 GO:0005504 fatty acid binding 2/1840 47/18639 0.0425531914893617 0.431059204440333 0.953717061616464 0.999999979028822 GO:0005179 hormone activity 8/1840 132/18639 0.0606060606060606 0.613932806324111 0.955615191272139 0.999999979028822 GO:0008194 UDP-glycosyltransferase activity 9/1840 145/18639 0.0620689655172414 0.628751874062969 0.955739681447561 0.999999979028822 GO:0001965 G-protein alpha-subunit binding 1/1840 30/18639 0.0333333333333333 0.337663043478261 0.95587210040386 0.999999979028822 GO:0022839 monoatomic ion-gated channel activity 1/1840 30/18639 0.0333333333333333 0.337663043478261 0.95587210040386 0.999999979028822 GO:0098918 structural constituent of synapse 1/1840 30/18639 0.0333333333333333 0.337663043478261 0.95587210040386 0.999999979028822 GO:0019199 transmembrane receptor protein kinase activity 4/1840 78/18639 0.0512820512820513 0.51948160535117 0.956444829850849 0.999999979028822 GO:0033293 monocarboxylic acid binding 4/1840 79/18639 0.0506329113924051 0.512905888827738 0.959409767975329 0.999999979028822 GO:0005184 neuropeptide hormone activity 1/1840 31/18639 0.032258064516129 0.326770687237027 0.960235329769054 0.999999979028822 GO:0047499 calcium-independent phospholipase A2 activity 1/1840 31/18639 0.032258064516129 0.326770687237027 0.960235329769054 0.999999979028822 GO:0015108 chloride transmembrane transporter activity 7/1840 121/18639 0.0578512396694215 0.586026769673015 0.960847455929452 0.999999979028822 GO:0005004 GPI-linked ephrin receptor activity 2/1840 49/18639 0.0408163265306122 0.41346495119787 0.961081583808746 0.999999979028822 GO:0005008 hepatocyte growth factor receptor activity 2/1840 49/18639 0.0408163265306122 0.41346495119787 0.961081583808746 0.999999979028822 GO:0005009 insulin receptor activity 2/1840 49/18639 0.0408163265306122 0.41346495119787 0.961081583808746 0.999999979028822 GO:0005011 macrophage colony-stimulating factor receptor activity 2/1840 49/18639 0.0408163265306122 0.41346495119787 0.961081583808746 0.999999979028822 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/1840 49/18639 0.0408163265306122 0.41346495119787 0.961081583808746 0.999999979028822 GO:0005020 stem cell factor receptor activity 2/1840 49/18639 0.0408163265306122 0.41346495119787 0.961081583808746 0.999999979028822 GO:0008288 boss receptor activity 2/1840 49/18639 0.0408163265306122 0.41346495119787 0.961081583808746 0.999999979028822 GO:0036332 placental growth factor receptor activity 2/1840 49/18639 0.0408163265306122 0.41346495119787 0.961081583808746 0.999999979028822 GO:0038062 protein tyrosine kinase collagen receptor activity 2/1840 49/18639 0.0408163265306122 0.41346495119787 0.961081583808746 0.999999979028822 GO:0060175 brain-derived neurotrophic factor receptor activity 2/1840 49/18639 0.0408163265306122 0.41346495119787 0.961081583808746 0.999999979028822 GO:0042562 hormone binding 5/1840 94/18639 0.0531914893617021 0.538824005550416 0.961564846643672 0.999999979028822 GO:0004843 cysteine-type deubiquitinase activity 6/1840 108/18639 0.0555555555555556 0.562771739130435 0.962010737202653 0.999999979028822 GO:0015106 bicarbonate transmembrane transporter activity 1/1840 32/18639 0.03125 0.31655910326087 0.964167347891633 0.999999979028822 GO:0047498 calcium-dependent phospholipase A2 activity 1/1840 32/18639 0.03125 0.31655910326087 0.964167347891633 0.999999979028822 GO:0160041 neuropeptide activity 1/1840 32/18639 0.03125 0.31655910326087 0.964167347891633 0.999999979028822 GO:0005006 epidermal growth factor receptor activity 2/1840 50/18639 0.04 0.405195652173913 0.964328335001936 0.999999979028822 GO:0005007 fibroblast growth factor receptor activity 2/1840 50/18639 0.04 0.405195652173913 0.964328335001936 0.999999979028822 GO:0005017 platelet-derived growth factor receptor activity 2/1840 50/18639 0.04 0.405195652173913 0.964328335001936 0.999999979028822 GO:0005019 platelet-derived growth factor beta-receptor activity 2/1840 50/18639 0.04 0.405195652173913 0.964328335001936 0.999999979028822 GO:0008509 monoatomic anion transmembrane transporter activity 9/1840 149/18639 0.0604026845637584 0.611872629121681 0.964332725010214 0.999999979028822 GO:0005010 insulin-like growth factor receptor activity 2/1840 51/18639 0.0392156862745098 0.397250639386189 0.967313770169165 0.999999979028822 GO:0005030 neurotrophin receptor activity 2/1840 51/18639 0.0392156862745098 0.397250639386189 0.967313770169165 0.999999979028822 GO:0019239 deaminase activity 1/1840 33/18639 0.0303030303030303 0.306966403162055 0.967710749830655 0.999999979028822 GO:0019956 chemokine binding 1/1840 33/18639 0.0303030303030303 0.306966403162055 0.967710749830655 0.999999979028822 GO:0015081 sodium ion transmembrane transporter activity 10/1840 164/18639 0.0609756097560976 0.617676299045599 0.968007956199375 0.999999979028822 GO:0005254 chloride channel activity 4/1840 83/18639 0.0481927710843374 0.488187532739654 0.969494780414895 0.999999979028822 GO:0005548 phospholipid transporter activity 3/1840 68/18639 0.0441176470588235 0.446906969309463 0.9697221928598 0.999999979028822 GO:0019787 ubiquitin-like protein transferase activity 36/1840 479/18639 0.0751565762004175 0.761327947717164 0.970097582777325 0.999999979028822 GO:0015020 glucuronosyltransferase activity 1/1840 34/18639 0.0294117647058824 0.297937979539642 0.970903925167192 0.999999979028822 GO:0016279 protein-lysine N-methyltransferase activity 3/1840 69/18639 0.0434782608695652 0.440430056710775 0.972013320012294 0.999999979028822 GO:0005003 ephrin receptor activity 2/1840 53/18639 0.0377358490566038 0.382260049220673 0.97257898056415 0.999999979028822 GO:0005005 transmembrane-ephrin receptor activity 2/1840 53/18639 0.0377358490566038 0.382260049220673 0.97257898056415 0.999999979028822 GO:0038064 collagen receptor activity 2/1840 53/18639 0.0377358490566038 0.382260049220673 0.97257898056415 0.999999979028822 GO:0004623 phospholipase A2 activity 1/1840 35/18639 0.0285714285714286 0.289425465838509 0.973781473014134 0.999999979028822 GO:0016278 lysine N-methyltransferase activity 3/1840 70/18639 0.0428571428571429 0.434138198757764 0.974139428335255 0.999999979028822 GO:0005516 calmodulin binding 13/1840 207/18639 0.0628019323671498 0.636176748582231 0.974653706293805 0.999999979028822 GO:0016755 aminoacyltransferase activity 37/1840 496/18639 0.0745967741935484 0.755657214235624 0.975004032944376 0.999999979028822 GO:0035591 signaling adaptor activity 7/1840 129/18639 0.0542635658914729 0.549684024266936 0.975826640132563 0.999999979028822 GO:0016409 palmitoyltransferase activity 1/1840 36/18639 0.0277777777777778 0.281385869565217 0.976374576091644 0.999999979028822 GO:0016758 hexosyltransferase activity 12/1840 197/18639 0.0609137055837563 0.617049216508497 0.978009442968482 0.999999979028822 GO:0030280 structural constituent of skin epidermis 1/1840 37/18639 0.027027027027027 0.273780846063455 0.978711337903791 0.999999979028822 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/1840 56/18639 0.0357142857142857 0.361781832298137 0.978971555587538 0.999999979028822 GO:0005253 monoatomic anion channel activity 5/1840 103/18639 0.0485436893203883 0.491742296327564 0.979088332757937 0.999999979028822 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/1840 73/18639 0.0410958904109589 0.416296902918404 0.979634754675346 0.999999979028822 GO:0005109 frizzled binding 1/1840 38/18639 0.0263157894736842 0.266576086956522 0.980817086654303 0.999999979028822 GO:0004497 monooxygenase activity 5/1840 106/18639 0.0471698113207547 0.477825061525841 0.98302558368961 0.999999979028822 GO:0017022 myosin binding 3/1840 76/18639 0.0394736842105263 0.399864130434783 0.984004712385222 0.999999979028822 GO:0005496 steroid binding 5/1840 108/18639 0.0462962962962963 0.468976449275362 0.985251069750717 0.999999979028822 GO:0004175 endopeptidase activity 28/1840 405/18639 0.0691358024691358 0.700338164251208 0.98572662357583 0.999999979028822 GO:0001727 lipid kinase activity 1/1840 41/18639 0.024390243902439 0.24707051961824 0.985965473176148 0.999999979028822 GO:0140828 metal cation:monoatomic cation antiporter activity 1/1840 41/18639 0.024390243902439 0.24707051961824 0.985965473176148 0.999999979028822 GO:0070851 growth factor receptor binding 7/1840 139/18639 0.0503597122302158 0.510138411010322 0.987118846105845 0.999999979028822 GO:0022824 transmitter-gated monoatomic ion channel activity 2/1840 63/18639 0.0317460317460317 0.321583850931677 0.988772364373066 0.999999979028822 GO:0022835 transmitter-gated channel activity 2/1840 63/18639 0.0317460317460317 0.321583850931677 0.988772364373066 0.999999979028822 GO:0004842 ubiquitin-protein transferase activity 31/1840 449/18639 0.0690423162583519 0.699391159097511 0.989511422225006 0.999999979028822 GO:0001653 peptide receptor activity 6/1840 128/18639 0.046875 0.474838654891304 0.989737825029983 0.999999979028822 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/1840 45/18639 0.0222222222222222 0.225108695652174 0.990748627670475 0.999999979028822 GO:0140303 intramembrane lipid transporter activity 1/1840 45/18639 0.0222222222222222 0.225108695652174 0.990748627670475 0.999999979028822 GO:0015171 amino acid transmembrane transporter activity 4/1840 102/18639 0.0392156862745098 0.397250639386189 0.992661972434089 0.999999979028822 GO:0032934 sterol binding 2/1840 68/18639 0.0294117647058824 0.297937979539642 0.992871552135623 0.999999979028822 GO:0008188 neuropeptide receptor activity 1/1840 48/18639 0.0208333333333333 0.211039402173913 0.993232386981586 0.999999979028822 GO:0098960 postsynaptic neurotransmitter receptor activity 2/1840 69/18639 0.0289855072463768 0.293620037807183 0.993494185930349 0.999999979028822 GO:0008236 serine-type peptidase activity 10/1840 194/18639 0.0515463917525773 0.522159345584939 0.994214721059309 0.999999979028822 GO:0008528 G protein-coupled peptide receptor activity 5/1840 122/18639 0.040983606557377 0.415159479686386 0.994647848635575 0.999999979028822 GO:0017171 serine hydrolase activity 10/1840 198/18639 0.0505050505050505 0.511610671936759 0.99546618989904 0.999999979028822 GO:0004713 protein tyrosine kinase activity 6/1840 140/18639 0.0428571428571429 0.434138198757764 0.995557004357601 0.999999979028822 GO:0043178 alcohol binding 3/1840 92/18639 0.0326086956521739 0.330322542533081 0.995754336522401 0.999999979028822 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/1840 53/18639 0.0188679245283019 0.191130024610336 0.995981168557045 0.999999979028822 GO:0015485 cholesterol binding 1/1840 54/18639 0.0185185185185185 0.187590579710145 0.996379029842692 0.999999979028822 GO:0004677 DNA-dependent protein kinase activity 13/1840 246/18639 0.0528455284552846 0.535319459172853 0.996897492883681 0.999999979028822 GO:0004252 serine-type endopeptidase activity 8/1840 176/18639 0.0454545454545455 0.460449604743083 0.997064543853042 0.999999979028822 GO:0035402 histone H3T11 kinase activity 13/1840 247/18639 0.0526315789473684 0.533152173913043 0.997071915423554 0.999999979028822 GO:0030594 neurotransmitter receptor activity 3/1840 97/18639 0.0309278350515464 0.313295607350964 0.997226309972484 0.999999979028822 GO:0008083 growth factor activity 7/1840 162/18639 0.0432098765432099 0.437711352657005 0.997248199813585 0.999999979028822 GO:0035401 histone H3Y41 kinase activity 4/1840 115/18639 0.0347826086956522 0.35234404536862 0.99737310028663 0.999999979028822 GO:0140801 histone H2AXY142 kinase activity 4/1840 115/18639 0.0347826086956522 0.35234404536862 0.99737310028663 0.999999979028822 GO:0004674 protein serine/threonine kinase activity 27/1840 433/18639 0.0623556581986143 0.631656039763028 0.997459437196028 0.999999979028822 GO:0099094 ligand-gated monoatomic cation channel activity 5/1840 136/18639 0.0367647058823529 0.372422474424552 0.998143940206817 0.999999979028822 GO:0005201 extracellular matrix structural constituent 7/1840 168/18639 0.0416666666666667 0.422078804347826 0.998194755621861 0.999999979028822 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 12/1840 243/18639 0.0493827160493827 0.50024154589372 0.998379839132837 0.999999979028822 GO:0015276 ligand-gated monoatomic ion channel activity 8/1840 186/18639 0.043010752688172 0.435694249649369 0.998511707931882 0.999999979028822 GO:0004676 3-phosphoinositide-dependent protein kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0004711 ribosomal protein S6 kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0035175 histone H3S10 kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0035979 histone H2AXS139 kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0044022 histone H3S28 kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0044023 histone H4S1 kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0044024 histone H2AS1 kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0044025 histone H2BS14 kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0072354 histone H3T3 kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0072371 histone H2AS121 kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0072518 Rho-dependent protein serine/threonine kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0140823 histone H2BS36 kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0140855 histone H3S57 kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0140995 histone H2A kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0140997 histone H4 kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0140998 histone H2B kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:1990244 histone H2AT120 kinase activity 12/1840 245/18639 0.0489795918367347 0.496157941437445 0.998566890296018 0.999999979028822 GO:0140857 histone H3T45 kinase activity 12/1840 246/18639 0.0487804878048781 0.494141039236479 0.998652500419727 0.999999979028822 GO:0022834 ligand-gated channel activity 8/1840 188/18639 0.0425531914893617 0.431059204440333 0.998703697273785 0.999999979028822 GO:0035403 histone H3T6 kinase activity 12/1840 247/18639 0.048582995951417 0.492140468227425 0.998733211142936 0.999999979028822 GO:0004679 AMP-activated protein kinase activity 12/1840 248/18639 0.0483870967741935 0.49015603085554 0.998809287980772 0.999999979028822 GO:0106310 protein serine kinase activity 20/1840 361/18639 0.0554016620498615 0.561212814645309 0.998997319205096 0.999999979028822 GO:0005249 voltage-gated potassium channel activity 2/1840 98/18639 0.0204081632653061 0.206732475598935 0.999567553998226 0.999999979028822 GO:0005261 monoatomic cation channel activity 17/1840 341/18639 0.0498533724340176 0.505009243911768 0.999692441392019 0.999999979028822 GO:0035173 histone kinase activity 18/1840 360/18639 0.05 0.506494565217391 0.999771153094393 0.999999979028822 GO:0046873 metal ion transmembrane transporter activity 24/1840 450/18639 0.0533333333333333 0.540260869565217 0.999850862237101 0.999999979028822 GO:0005262 calcium channel activity 3/1840 131/18639 0.0229007633587786 0.231982243611019 0.999861634973499 0.999999979028822 GO:0140996 histone H3 kinase activity 17/1840 357/18639 0.0476190476190476 0.482375776397515 0.99988260543946 0.999999979028822 GO:0022832 voltage-gated channel activity 5/1840 175/18639 0.0285714285714286 0.289425465838509 0.999918895342793 0.999999979028822 GO:0015079 potassium ion transmembrane transporter activity 4/1840 160/18639 0.025 0.253247282608696 0.999940049279017 0.999999979028822 GO:0141003 histone H2AX kinase activity 16/1840 354/18639 0.0451977401129944 0.457848194546794 0.999942519778803 0.999999979028822 GO:0030527 structural constituent of chromatin 1/1840 98/18639 0.0102040816326531 0.103366237799468 0.999963340575562 0.999999979028822 GO:0005267 potassium channel activity 2/1840 124/18639 0.0161290322580645 0.163385343618513 0.999964520957721 0.999999979028822 GO:0015085 calcium ion transmembrane transporter activity 3/1840 147/18639 0.0204081632653061 0.206732475598935 0.999967807163112 0.999999979028822 GO:0005216 monoatomic ion channel activity 21/1840 448/18639 0.046875 0.474838654891304 0.999985190899164 0.999999979028822 GO:0045182 translation regulator activity 14/1840 356/18639 0.0393258426966292 0.398366511968735 0.999993212969415 0.999999979028822 GO:0022843 voltage-gated monoatomic cation channel activity 2/1840 143/18639 0.013986013986014 0.14167680145941 0.999994450406007 0.999999979028822 GO:0005244 voltage-gated monoatomic ion channel activity 3/1840 173/18639 0.0173410404624277 0.175662854988691 0.999997125497178 0.999999979028822 GO:0022836 gated channel activity 10/1840 318/18639 0.0314465408805031 0.318550041017227 0.999999056426094 0.999999979028822 GO:0030371 translation repressor activity 8/1840 329/18639 0.0243161094224924 0.246319545394476 0.999999979028822 0.999999979028822