ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0030695	GTPase regulator activity	78/1163	489/18639	0.159509202453988	2.55639898928622	1.36129122211637e-14	8.19184900066957e-12
GO:0060589	nucleoside-triphosphatase regulator activity	78/1163	490/18639	0.159183673469388	2.55118184849176	1.52406493035713e-14	8.19184900066957e-12
GO:0140996	histone H3 kinase activity	56/1163	357/18639	0.156862745098039	2.51398512973547	1.51669628020191e-10	5.43482833739017e-08
GO:0035173	histone kinase activity	56/1163	360/18639	0.155555555555556	2.49303525365434	2.10223393722521e-10	5.64975370629276e-08
GO:0005085	guanyl-nucleotide exchange factor activity	42/1163	230/18639	0.182608695652174	2.92660660211597	2.77280110758325e-10	5.72853266174379e-08
GO:0141003	histone H2AX kinase activity	55/1163	354/18639	0.155367231638418	2.49001705116808	3.19732055539188e-10	5.72853266174379e-08
GO:0003712	transcription coregulator activity	66/1163	495/18639	0.133333333333333	2.13688736027515	3.96659642408039e-09	6.09155879412345e-07
GO:0045296	cadherin binding	50/1163	334/18639	0.149700598802395	2.39919988054845	7.31368274557746e-09	9.77106302859506e-07
GO:0051020	GTPase binding	48/1163	315/18639	0.152380952380952	2.4421569831716	8.18042486114935e-09	9.77106302859506e-07
GO:0004812	aminoacyl-tRNA ligase activity	15/1163	41/18639	0.365853658536585	5.86341043977938	1.05284044108664e-08	9.97839728910193e-07
GO:0016875	ligase activity, forming carbon-oxygen bonds	15/1163	41/18639	0.365853658536585	5.86341043977938	1.05284044108664e-08	9.97839728910193e-07
GO:0003779	actin binding	60/1163	443/18639	0.135440180586907	2.1706530747716	1.13706592671867e-08	9.97839728910193e-07
GO:0004674	protein serine/threonine kinase activity	59/1163	433/18639	0.136258660508083	2.18377057025809	1.2066899047286e-08	9.97839728910193e-07
GO:0005543	phospholipid binding	64/1163	497/18639	0.128772635814889	2.06379463366614	2.64671301196076e-08	2.03229749132701e-06
GO:0071889	14-3-3 protein binding	13/1163	33/18639	0.393939393939394	6.31353083717658	3.60142189895509e-08	2.58101902758448e-06
GO:0005096	GTPase activator activity	42/1163	271/18639	0.154981549815498	2.48383586157444	4.27365578725473e-08	2.87136248206177e-06
GO:0035402	histone H3T11 kinase activity	38/1163	247/18639	0.153846153846154	2.46563926185594	2.26161800074817e-07	1.4014363035246e-05
GO:0106310	protein serine kinase activity	49/1163	361/18639	0.135734072022161	2.17536317147124	2.34659101985514e-07	1.4014363035246e-05
GO:0031267	small GTPase binding	41/1163	283/18639	0.144876325088339	2.32188290913289	4.00471394726534e-07	1.51137796954789e-05
GO:0035091	phosphatidylinositol binding	41/1163	284/18639	0.144366197183099	2.31370726508665	4.40489091147942e-07	1.51137796954789e-05
GO:0004676	3-phosphoinositide-dependent protein kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0004711	ribosomal protein S6 kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0035175	histone H3S10 kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0035979	histone H2AXS139 kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0044022	histone H3S28 kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0044023	histone H4S1 kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0044024	histone H2AS1 kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0044025	histone H2BS14 kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0072354	histone H3T3 kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0072371	histone H2AS121 kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0072518	Rho-dependent protein serine/threonine kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0140823	histone H2BS36 kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0140855	histone H3S57 kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0140995	histone H2A kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0140997	histone H4 kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0140998	histone H2B kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:1990244	histone H2AT120 kinase activity	37/1163	245/18639	0.151020408163265	2.42035201010757	5.2019520812346e-07	1.51137796954789e-05
GO:0004677	DNA-dependent protein kinase activity	37/1163	246/18639	0.150406504065041	2.41051318079819	5.76291053380722e-07	1.58849457021609e-05
GO:0140857	histone H3T45 kinase activity	37/1163	246/18639	0.150406504065041	2.41051318079819	5.76291053380722e-07	1.58849457021609e-05
GO:0035403	histone H3T6 kinase activity	37/1163	247/18639	0.149797570850202	2.40075401812289	6.37980493248902e-07	1.71457257560642e-05
GO:0004679	AMP-activated protein kinase activity	37/1163	248/18639	0.149193548387097	2.3910735583724	7.05774000621959e-07	1.85050500163075e-05
GO:0019838	growth factor binding	25/1163	136/18639	0.183823529411765	2.94607632390876	9.74565085189493e-07	2.49442253947311e-05
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	36/1163	243/18639	0.148148148148148	2.37431928919461	1.17846360548783e-06	2.94615901371958e-05
GO:0046965	nuclear retinoid X receptor binding	8/1163	17/18639	0.470588235294118	7.54195538920641	3.28323803919602e-06	8.02154748212665e-05
GO:0140297	DNA-binding transcription factor binding	57/1163	488/18639	0.116803278688525	1.87196587401153	3.64919399939055e-06	8.71751899854408e-05
GO:0016874	ligase activity	27/1163	167/18639	0.161676646706587	2.59113587099232	4.79517977784277e-06	0.000111788197847575
GO:0019199	transmembrane receptor protein kinase activity	17/1163	78/18639	0.217948717948718	3.49298895429592	4.88748399891722e-06	0.000111788197847575
GO:0046332	SMAD binding	17/1163	79/18639	0.215189873417722	3.44877390424154	5.86964600541239e-06	0.000131455613662882
GO:0042974	nuclear retinoic acid receptor binding	9/1163	25/18639	0.36	5.76959587274291	1.14078868814956e-05	0.000250275069338934
GO:0051015	actin filament binding	30/1163	209/18639	0.143540669856459	2.30047682326272	1.68021241314023e-05	0.000361245668825149
GO:0004713	protein tyrosine kinase activity	23/1163	140/18639	0.164285714285714	2.63295049748188	1.81623292609413e-05	0.00038283341089239
GO:0003713	transcription coactivator activity	34/1163	256/18639	0.1328125	2.12854014402408	2.53585658015616e-05	0.000524239581474591
GO:0017124	SH3 domain binding	20/1163	115/18639	0.173913043478261	2.78724438296759	2.69642507734537e-05	0.000527028537844778
GO:0035401	histone H3Y41 kinase activity	20/1163	115/18639	0.173913043478261	2.78724438296759	2.69642507734537e-05	0.000527028537844778
GO:0140801	histone H2AXY142 kinase activity	20/1163	115/18639	0.173913043478261	2.78724438296759	2.69642507734537e-05	0.000527028537844778
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	42/1163	349/18639	0.120343839541547	1.92870922202485	3.38738425438995e-05	0.000650256798833786
GO:0016755	aminoacyltransferase activity	54/1163	496/18639	0.108870967741935	1.74483746151499	4.73926984967737e-05	0.000893809664632136
GO:0005021	vascular endothelial growth factor receptor activity	12/1163	51/18639	0.235294117647059	3.77097769460321	5.38812759040085e-05	0.00099866157925533
GO:0031210	phosphatidylcholine binding	9/1163	30/18639	0.3	4.80799656061909	6.01600630931743e-05	0.00109613674279936
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	13/1163	60/18639	0.216666666666667	3.47244196044712	6.70316072228683e-05	0.00120098296274306
GO:0038064	collagen receptor activity	12/1163	53/18639	0.226415094339623	3.62867664952384	8.0654491019321e-05	0.00142137012861918
GO:0140938	histone H3 methyltransferase activity	11/1163	47/18639	0.234042553191489	3.75091930261064	0.000115543203079146	0.00198428514991655
GO:0016922	nuclear receptor binding	21/1163	137/18639	0.153284671532847	2.45664057841851	0.000116288339018366	0.00198428514991655
GO:0019787	ubiquitin-like protein transferase activity	51/1163	479/18639	0.106471816283925	1.70638708831993	0.000133589807670061	0.00224389130070805
GO:0005004	GPI-linked ephrin receptor activity	11/1163	49/18639	0.224489795918367	3.5978205555653	0.000172321937894047	0.0025033254491365
GO:0005008	hepatocyte growth factor receptor activity	11/1163	49/18639	0.224489795918367	3.5978205555653	0.000172321937894047	0.0025033254491365
GO:0005009	insulin receptor activity	11/1163	49/18639	0.224489795918367	3.5978205555653	0.000172321937894047	0.0025033254491365
GO:0005011	macrophage colony-stimulating factor receptor activity	11/1163	49/18639	0.224489795918367	3.5978205555653	0.000172321937894047	0.0025033254491365
GO:0005018	platelet-derived growth factor alpha-receptor activity	11/1163	49/18639	0.224489795918367	3.5978205555653	0.000172321937894047	0.0025033254491365
GO:0005020	stem cell factor receptor activity	11/1163	49/18639	0.224489795918367	3.5978205555653	0.000172321937894047	0.0025033254491365
GO:0008288	boss receptor activity	11/1163	49/18639	0.224489795918367	3.5978205555653	0.000172321937894047	0.0025033254491365
GO:0036332	placental growth factor receptor activity	11/1163	49/18639	0.224489795918367	3.5978205555653	0.000172321937894047	0.0025033254491365
GO:0038062	protein tyrosine kinase collagen receptor activity	11/1163	49/18639	0.224489795918367	3.5978205555653	0.000172321937894047	0.0025033254491365
GO:0060175	brain-derived neurotrophic factor receptor activity	11/1163	49/18639	0.224489795918367	3.5978205555653	0.000172321937894047	0.0025033254491365
GO:0003714	transcription corepressor activity	27/1163	204/18639	0.132352941176471	2.1211749532143	0.000176469618140299	0.00252939786001096
GO:0004842	ubiquitin-protein transferase activity	48/1163	449/18639	0.106904231625835	1.71331725990881	0.000189185150426638	0.0026759741672189
GO:0005006	epidermal growth factor receptor activity	11/1163	50/18639	0.22	3.525864144454	0.000208611540113894	0.00280321757028045
GO:0005007	fibroblast growth factor receptor activity	11/1163	50/18639	0.22	3.525864144454	0.000208611540113894	0.00280321757028045
GO:0005017	platelet-derived growth factor receptor activity	11/1163	50/18639	0.22	3.525864144454	0.000208611540113894	0.00280321757028045
GO:0005019	platelet-derived growth factor beta-receptor activity	11/1163	50/18639	0.22	3.525864144454	0.000208611540113894	0.00280321757028045
GO:0016500	protein-hormone receptor activity	13/1163	67/18639	0.194029850746269	3.10964951681832	0.000219247043994451	0.00290976015177821
GO:0005010	insulin-like growth factor receptor activity	11/1163	51/18639	0.215686274509804	3.45672955338627	0.000251162362771612	0.0032530065057769
GO:0005030	neurotrophin receptor activity	11/1163	51/18639	0.215686274509804	3.45672955338627	0.000251162362771612	0.0032530065057769
GO:0050321	tau-protein kinase activity	7/1163	22/18639	0.318181818181818	5.0993902915657	0.000268730877549234	0.0034272209818076
GO:0070411	I-SMAD binding	6/1163	16/18639	0.375	6.00999570077386	0.000270989566003391	0.0034272209818076
GO:0004714	transmembrane receptor protein tyrosine kinase activity	12/1163	60/18639	0.2	3.20533104041273	0.000282432447624415	0.00353040559530519
GO:0008081	phosphoric diester hydrolase activity	15/1163	87/18639	0.172413793103448	2.7632164141489	0.000291964951133915	0.00360761290194205
GO:0019902	phosphatase binding	25/1163	190/18639	0.131578947368421	2.10877042132416	0.000330159162396561	0.00403319431336708
GO:0016278	lysine N-methyltransferase activity	13/1163	70/18639	0.185714285714286	2.97637882324039	0.000344744095238453	0.00416404384698131
GO:0005003	ephrin receptor activity	11/1163	53/18639	0.207547169811321	3.32628692873019	0.000358471203176961	0.00423468729027728
GO:0005005	transmembrane-ephrin receptor activity	11/1163	53/18639	0.207547169811321	3.32628692873019	0.000358471203176961	0.00423468729027728
GO:0004715	non-membrane spanning protein tyrosine kinase activity	10/1163	45/18639	0.222222222222222	3.56147893379192	0.000368970012190197	0.00431133438157023
GO:0031624	ubiquitin conjugating enzyme binding	8/1163	30/18639	0.266666666666667	4.2737747205503	0.000381508959624772	0.00440991539351215
GO:0017166	vinculin binding	5/1163	12/18639	0.416666666666667	6.67777300085984	0.000512996776553107	0.00586671845526159
GO:0008525	phosphatidylcholine transporter activity	6/1163	18/18639	0.333333333333333	5.34221840068788	0.000563900297526393	0.00638097705095655
GO:0015631	tubulin binding	41/1163	385/18639	0.106493506493506	1.70673470983015	0.000582851109266715	0.0065267181506429
GO:0031491	nucleosome binding	13/1163	74/18639	0.175675675675676	2.81549348144361	0.000603136878068867	0.00668424890643332
GO:0050997	quaternary ammonium group binding	9/1163	40/18639	0.225	3.60599742046432	0.000653945674030568	0.00717338366921286
GO:0042578	phosphoric ester hydrolase activity	39/1163	363/18639	0.107438016528926	1.7218720465027	0.000661476335034828	0.00718269757739839
GO:0061630	ubiquitin protein ligase activity	38/1163	353/18639	0.107648725212465	1.72524900192186	0.000742459810331266	0.00798144296106111
GO:0005035	death receptor activity	5/1163	13/18639	0.384615384615385	6.16409815463986	0.000790922645529679	0.00833570435239612
GO:0046975	histone H3K36 methyltransferase activity	5/1163	13/18639	0.384615384615385	6.16409815463986	0.000790922645529679	0.00833570435239612
GO:0034237	protein kinase A regulatory subunit binding	7/1163	26/18639	0.269230769230769	4.3148687082479	0.000832057763222558	0.00868409801421601
GO:0045309	protein phosphorylated amino acid binding	11/1163	59/18639	0.186440677966102	2.98802046140169	0.00093416957375604	0.00965607972872829
GO:0140101	catalytic activity, acting on a tRNA	19/1163	139/18639	0.136690647482014	2.19069387654107	0.00103373408913621	0.0105288695872549
GO:0019207	kinase regulator activity	32/1163	287/18639	0.111498257839721	1.786944134028	0.00105271952915002	0.0105288695872549
GO:0061659	ubiquitin-like protein ligase activity	39/1163	372/18639	0.104838709677419	1.68021385182925	0.00105415597520715	0.0105288695872549
GO:0016279	protein-lysine N-methyltransferase activity	12/1163	69/18639	0.173913043478261	2.78724438296759	0.00106043814092093	0.0105288695872549
GO:0008170	N-methyltransferase activity	15/1163	98/18639	0.153061224489796	2.45305946970362	0.00106757840466119	0.0105288695872549
GO:0098531	ligand-modulated transcription factor activity	11/1163	60/18639	0.183333333333333	2.93822012037833	0.00108047790819375	0.0105592159209844
GO:0046875	ephrin receptor binding	7/1163	28/18639	0.25	4.00666380051591	0.00134236299303877	0.012884287656399
GO:0141052	histone H3 demethylase activity	7/1163	28/18639	0.25	4.00666380051591	0.00134236299303877	0.012884287656399
GO:0044390	ubiquitin-like protein conjugating enzyme binding	8/1163	36/18639	0.222222222222222	3.56147893379192	0.00141308431251344	0.0134430587252385
GO:0051018	protein kinase A binding	10/1163	53/18639	0.188679245283019	3.02389720793653	0.00143307985113919	0.0135043479928467
GO:0001618	virus receptor activity	13/1163	81/18639	0.160493827160494	2.57217922996083	0.00144465118063011	0.0135043479928467
GO:0140272	exogenous protein binding	13/1163	82/18639	0.158536585365854	2.54081119057106	0.00162078239713194	0.015020181697559
GO:0051213	dioxygenase activity	14/1163	93/18639	0.150537634408602	2.41261476160098	0.0018183796008828	0.0167073339397351
GO:0032452	histone demethylase activity	7/1163	30/18639	0.233333333333333	3.73955288048151	0.00206913454712665	0.0188501664250945
GO:0005024	transforming growth factor beta receptor activity	5/1163	16/18639	0.3125	5.00832975064488	0.00229388073883091	0.0207220318843969
GO:0031720	haptoglobin binding	4/1163	10/18639	0.4	6.41066208082545	0.00233612543903387	0.020823308949437
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	6/1163	23/18639	0.260869565217391	4.18086657445138	0.00234383291430872	0.020823308949437
GO:0070273	phosphatidylinositol-4-phosphate binding	7/1163	31/18639	0.225806451612903	3.61892214240146	0.00253078147793677	0.022118618607984
GO:0140457	protein demethylase activity	7/1163	31/18639	0.225806451612903	3.61892214240146	0.00253078147793677	0.022118618607984
GO:0019887	protein kinase regulator activity	28/1163	255/18639	0.109803921568627	1.75978959081483	0.00261771259685461	0.0226938793678928
GO:0042054	histone methyltransferase activity	11/1163	67/18639	0.164179104477612	2.63124189884627	0.00272081405231391	0.0233990008498996
GO:0032451	demethylase activity	8/1163	40/18639	0.2	3.20533104041273	0.00287831290443053	0.0244955631035223
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	6/1163	24/18639	0.25	4.00666380051591	0.00296225414275154	0.0244955631035223
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	6/1163	24/18639	0.25	4.00666380051591	0.00296225414275154	0.0244955631035223
GO:0050431	transforming growth factor beta binding	6/1163	24/18639	0.25	4.00666380051591	0.00296225414275154	0.0244955631035223
GO:0070300	phosphatidic acid binding	6/1163	24/18639	0.25	4.00666380051591	0.00296225414275154	0.0244955631035223
GO:0004879	nuclear receptor activity	10/1163	59/18639	0.169491525423729	2.7163822376379	0.00329185288152073	0.0270132965468304
GO:0042169	SH2 domain binding	8/1163	41/18639	0.195121951219512	3.127152234549	0.00338406654667063	0.0275596328611434
GO:0008526	phosphatidylinositol transfer activity	4/1163	11/18639	0.363636363636364	5.82787461893223	0.00349080820101478	0.0277971764154881
GO:0034713	type I transforming growth factor beta receptor binding	4/1163	11/18639	0.363636363636364	5.82787461893223	0.00349080820101478	0.0277971764154881
GO:0048185	activin binding	4/1163	11/18639	0.363636363636364	5.82787461893223	0.00349080820101478	0.0277971764154881
GO:0031492	nucleosomal DNA binding	8/1163	42/18639	0.19047619047619	3.0526962289645	0.00395607032323951	0.0310421576458575
GO:0048487	beta-tubulin binding	8/1163	42/18639	0.19047619047619	3.0526962289645	0.00395607032323951	0.0310421576458575
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	5/1163	18/18639	0.277777777777778	4.4518486672399	0.00405374173079212	0.0313508802920973
GO:0070064	proline-rich region binding	5/1163	18/18639	0.277777777777778	4.4518486672399	0.00405374173079212	0.0313508802920973
GO:0004112	cyclic-nucleotide phosphodiesterase activity	6/1163	26/18639	0.230769230769231	3.69845889278391	0.0045537074514871	0.0344734895094974
GO:0004435	phosphatidylinositol phospholipase C activity	6/1163	26/18639	0.230769230769231	3.69845889278391	0.0045537074514871	0.0344734895094974
GO:0052742	phosphatidylinositol kinase activity	6/1163	26/18639	0.230769230769231	3.69845889278391	0.0045537074514871	0.0344734895094974
GO:0048156	tau protein binding	8/1163	43/18639	0.186046511627907	2.98170329340719	0.00459984447203219	0.0345792504016406
GO:0044325	transmembrane transporter binding	17/1163	136/18639	0.125	2.00333190025795	0.00477086056338389	0.0356157993447062
GO:0005025	transforming growth factor beta receptor activity, type I	4/1163	12/18639	0.333333333333333	5.34221840068788	0.00497971391324561	0.0356879497115935
GO:0005026	transforming growth factor beta receptor activity, type II	4/1163	12/18639	0.333333333333333	5.34221840068788	0.00497971391324561	0.0356879497115935
GO:0016361	activin receptor activity, type I	4/1163	12/18639	0.333333333333333	5.34221840068788	0.00497971391324561	0.0356879497115935
GO:0016362	activin receptor activity, type II	4/1163	12/18639	0.333333333333333	5.34221840068788	0.00497971391324561	0.0356879497115935
GO:0017002	activin receptor activity	4/1163	12/18639	0.333333333333333	5.34221840068788	0.00497971391324561	0.0356879497115935
GO:0034452	dynactin binding	4/1163	12/18639	0.333333333333333	5.34221840068788	0.00497971391324561	0.0356879497115935
GO:0051219	phosphoprotein binding	13/1163	93/18639	0.139784946236559	2.24028513577233	0.00501580321838217	0.0357085328460982
GO:0005154	epidermal growth factor receptor binding	7/1163	35/18639	0.2	3.20533104041273	0.00520677052626397	0.0368241994456169
GO:1901981	phosphatidylinositol phosphate binding	21/1163	185/18639	0.113513513513514	1.81924194185587	0.00579198075766228	0.0406952896371696
GO:0008276	protein methyltransferase activity	13/1163	95/18639	0.136842105263158	2.19312123817713	0.00601471972483645	0.0419858682090856
GO:0045505	dynein intermediate chain binding	7/1163	36/18639	0.194444444444444	3.11629406706793	0.00612248788820375	0.0420355129020283
GO:0008013	beta-catenin binding	14/1163	106/18639	0.132075471698113	2.11672804555557	0.00612807534812196	0.0420355129020283
GO:0019208	phosphatase regulator activity	15/1163	117/18639	0.128205128205128	2.05469938487995	0.0061391400238311	0.0420355129020283
GO:0019888	protein phosphatase regulator activity	14/1163	107/18639	0.130841121495327	2.09694554045692	0.00665718184052972	0.04511965546137
GO:0008035	high-density lipoprotein particle binding	4/1163	13/18639	0.307692307692308	4.93127852371189	0.00684139892111936	0.04511965546137
GO:0031994	insulin-like growth factor I binding	4/1163	13/18639	0.307692307692308	4.93127852371189	0.00684139892111936	0.04511965546137
GO:0046974	histone H3K9 methyltransferase activity	4/1163	13/18639	0.307692307692308	4.93127852371189	0.00684139892111936	0.04511965546137
GO:0070123	transforming growth factor beta receptor activity, type III	4/1163	13/18639	0.307692307692308	4.93127852371189	0.00684139892111936	0.04511965546137
GO:0140852	histone ubiquitin ligase activity	4/1163	13/18639	0.307692307692308	4.93127852371189	0.00684139892111936	0.04511965546137
GO:0030291	protein serine/threonine kinase inhibitor activity	8/1163	46/18639	0.173913043478261	2.78724438296759	0.00701876882159283	0.0460071736781237
GO:0030527	structural constituent of chromatin	13/1163	98/18639	0.13265306122449	2.12598487374313	0.00780363248426921	0.0508418480035721
GO:0001784	phosphotyrosine residue binding	8/1163	47/18639	0.170212765957447	2.72794131098955	0.00800702759810557	0.051249203985243
GO:0004629	phospholipase C activity	6/1163	29/18639	0.206896551724138	3.31585969697868	0.00800917792513564	0.051249203985243
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	6/1163	29/18639	0.206896551724138	3.31585969697868	0.00800917792513564	0.051249203985243
GO:0008373	sialyltransferase activity	5/1163	21/18639	0.238095238095238	3.81587028620563	0.00823874338109958	0.0524062078975269
GO:0019903	protein phosphatase binding	17/1163	144/18639	0.118055555555556	1.89203568357696	0.00841534354414409	0.0532146724114994
GO:0016879	ligase activity, forming carbon-nitrogen bonds	8/1163	48/18639	0.166666666666667	2.67110920034394	0.00909609360693255	0.0553351296932871
GO:0005344	oxygen carrier activity	4/1163	14/18639	0.285714285714286	4.57904434344675	0.00911099344717379	0.0553351296932871
GO:0005545	1-phosphatidylinositol binding	4/1163	14/18639	0.285714285714286	4.57904434344675	0.00911099344717379	0.0553351296932871
GO:0032454	histone H3K9 demethylase activity	4/1163	14/18639	0.285714285714286	4.57904434344675	0.00911099344717379	0.0553351296932871
GO:0034236	protein kinase A catalytic subunit binding	4/1163	14/18639	0.285714285714286	4.57904434344675	0.00911099344717379	0.0553351296932871
GO:0070742	C2H2 zinc finger domain binding	4/1163	14/18639	0.285714285714286	4.57904434344675	0.00911099344717379	0.0553351296932871
GO:0098821	BMP receptor activity	4/1163	14/18639	0.285714285714286	4.57904434344675	0.00911099344717379	0.0553351296932871
GO:0005548	phospholipid transporter activity	10/1163	68/18639	0.147058823529412	2.356861059127	0.00919584543012135	0.0555367069515756
GO:0019209	kinase activator activity	17/1163	148/18639	0.114864864864865	1.84089958402082	0.0109329842464085	0.0656589836027329
GO:0030331	nuclear estrogen receptor binding	7/1163	40/18639	0.175	2.80466466036113	0.0110154340047969	0.0657866197508704
GO:0005178	integrin binding	18/1163	161/18639	0.111801242236025	1.79179996047916	0.0117417387597111	0.0690559990969325
GO:0043178	alcohol binding	12/1163	92/18639	0.130434782608696	2.09043328722569	0.0117709479382634	0.0690559990969325
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/1163	15/18639	0.266666666666667	4.2737747205503	0.0118198175198471	0.0690559990969325
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/1163	15/18639	0.266666666666667	4.2737747205503	0.0118198175198471	0.0690559990969325
GO:0001727	lipid kinase activity	7/1163	41/18639	0.170731707317073	2.73625820523038	0.0125865978932347	0.0727451222324046
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	7/1163	41/18639	0.170731707317073	2.73625820523038	0.0125865978932347	0.0727451222324046
GO:0042826	histone deacetylase binding	15/1163	127/18639	0.118110236220472	1.8929120317398	0.0127611702846051	0.0733596687483983
GO:0031490	chromatin DNA binding	15/1163	128/18639	0.1171875	1.87812365649183	0.0136491561460883	0.0780470364736432
GO:0030165	PDZ domain binding	11/1163	83/18639	0.132530120481928	2.12401454485181	0.0138513133503362	0.078783925140801
GO:0030552	cAMP binding	5/1163	24/18639	0.208333333333333	3.33888650042992	0.0147390720387479	0.0833921181139683
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	4/1163	16/18639	0.25	4.00666380051591	0.0149951297801858	0.0843966728465954
GO:0140416	transcription regulator inhibitor activity	6/1163	33/18639	0.181818181818182	2.91393730946611	0.0151111685784374	0.0846068032386467
GO:0008375	acetylglucosaminyltransferase activity	7/1163	43/18639	0.162790697674419	2.60899038173129	0.0162013148668562	0.0902404843620229
GO:0005496	steroid binding	13/1163	108/18639	0.12037037037037	1.92913442247062	0.0169295337448047	0.0938105606993045
GO:0003707	nuclear steroid receptor activity	5/1163	25/18639	0.2	3.20533104041273	0.0175001237445014	0.0964750411555846
GO:0015485	cholesterol binding	8/1163	54/18639	0.148148148148148	2.37431928919461	0.0180757865262877	0.0991401556926496
GO:0008429	phosphatidylethanolamine binding	4/1163	17/18639	0.235294117647059	3.77097769460321	0.018659987764039	0.101310539627989
GO:0038191	neuropilin binding	4/1163	17/18639	0.235294117647059	3.77097769460321	0.018659987764039	0.101310539627989
GO:0120013	lipid transfer activity	9/1163	65/18639	0.138461538461538	2.21907533567035	0.0190257858688207	0.102777486477298
GO:0005112	Notch binding	5/1163	26/18639	0.192307692307692	3.08204907731993	0.0205826038142667	0.108959773532759
GO:0005160	transforming growth factor beta receptor binding	5/1163	26/18639	0.192307692307692	3.08204907731993	0.0205826038142667	0.108959773532759
GO:0043548	phosphatidylinositol 3-kinase binding	5/1163	26/18639	0.192307692307692	3.08204907731993	0.0205826038142667	0.108959773532759
GO:0070412	R-SMAD binding	5/1163	26/18639	0.192307692307692	3.08204907731993	0.0205826038142667	0.108959773532759
GO:0005031	tumor necrosis factor receptor activity	3/1163	10/18639	0.3	4.80799656061909	0.0208797333467427	0.108959773532759
GO:0008140	cAMP response element binding protein binding	3/1163	10/18639	0.3	4.80799656061909	0.0208797333467427	0.108959773532759
GO:0051864	histone H3K36 demethylase activity	3/1163	10/18639	0.3	4.80799656061909	0.0208797333467427	0.108959773532759
GO:0098641	cadherin binding involved in cell-cell adhesion	4/1163	18/18639	0.222222222222222	3.56147893379192	0.0228332009163952	0.118578217319444
GO:0031625	ubiquitin protein ligase binding	28/1163	302/18639	0.0927152317880795	1.48591505184696	0.0235898680264502	0.12191878907901
GO:0019210	kinase inhibitor activity	11/1163	90/18639	0.122222222222222	1.95881341358555	0.0241282955501996	0.124104869456768
GO:0004721	phosphoprotein phosphatase activity	18/1163	175/18639	0.102857142857143	1.64845596364083	0.0254280980266374	0.130167644660168
GO:0000049	tRNA binding	10/1163	80/18639	0.125	2.00333190025795	0.0267213596971079	0.136139628788583
GO:0030295	protein kinase activator activity	15/1163	139/18639	0.107913669064748	1.72949516569032	0.0268780578029555	0.13626383697081
GO:0019864	IgG binding	3/1163	11/18639	0.272727272727273	4.37090596419917	0.0274005802763906	0.13626383697081
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/1163	11/18639	0.272727272727273	4.37090596419917	0.0274005802763906	0.13626383697081
GO:0005520	insulin-like growth factor binding	4/1163	19/18639	0.210526315789474	3.37403267411866	0.0275293599669153	0.13626383697081
GO:0042800	histone H3K4 methyltransferase activity	4/1163	19/18639	0.210526315789474	3.37403267411866	0.0275293599669153	0.13626383697081
GO:0046624	sphingolipid transporter activity	4/1163	19/18639	0.210526315789474	3.37403267411866	0.0275293599669153	0.13626383697081
GO:0051959	dynein light intermediate chain binding	5/1163	28/18639	0.178571428571429	2.86190271465422	0.0277597956247511	0.13626383697081
GO:0097718	disordered domain specific binding	5/1163	28/18639	0.178571428571429	2.86190271465422	0.0277597956247511	0.13626383697081
GO:0032266	phosphatidylinositol-3-phosphate binding	7/1163	48/18639	0.145833333333333	2.33722055030095	0.0283270379194392	0.138416208015441
GO:0001786	phosphatidylserine binding	8/1163	59/18639	0.135593220338983	2.17310579011032	0.0293719249871231	0.142466712414708
GO:0097110	scaffold protein binding	9/1163	70/18639	0.128571428571429	2.06056995455104	0.0294210327033163	0.142466712414708
GO:0003785	actin monomer binding	5/1163	29/18639	0.172413793103448	2.7632164141489	0.0318745076455042	0.153655137752991
GO:0031418	L-ascorbic acid binding	4/1163	20/18639	0.2	3.20533104041273	0.0327589284095894	0.157213607322806
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	18/1163	181/18639	0.0994475138121547	1.59381101456986	0.0340598837267833	0.162293366135268
GO:0005516	calmodulin binding	20/1163	207/18639	0.0966183574879227	1.54846910164866	0.0346197164649528	0.162293366135268
GO:0031543	peptidyl-proline dioxygenase activity	3/1163	12/18639	0.25	4.00666380051591	0.0348742023974389	0.162293366135268
GO:0035259	nuclear glucocorticoid receptor binding	3/1163	12/18639	0.25	4.00666380051591	0.0348742023974389	0.162293366135268
GO:0070410	co-SMAD binding	3/1163	12/18639	0.25	4.00666380051591	0.0348742023974389	0.162293366135268
GO:0070679	inositol 1,4,5 trisphosphate binding	3/1163	12/18639	0.25	4.00666380051591	0.0348742023974389	0.162293366135268
GO:1990247	N6-methyladenosine-containing RNA reader activity	3/1163	12/18639	0.25	4.00666380051591	0.0348742023974389	0.162293366135268
GO:0004860	protein kinase inhibitor activity	10/1163	84/18639	0.119047619047619	1.90793514310281	0.0359310898681547	0.166491041414941
GO:0046982	protein heterodimerization activity	32/1163	369/18639	0.0867208672086721	1.38984543757733	0.0374278515031573	0.172682147493108
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	4/1163	21/18639	0.19047619047619	3.0526962289645	0.0385283837104106	0.176246861654006
GO:0009931	calcium-dependent protein serine/threonine kinase activity	4/1163	21/18639	0.19047619047619	3.0526962289645	0.0385283837104106	0.176246861654006
GO:0017080	sodium channel regulator activity	6/1163	41/18639	0.146341463414634	2.34536417591175	0.040332587823532	0.183718355552105
GO:0002161	aminoacyl-tRNA editing activity	3/1163	13/18639	0.230769230769231	3.69845889278391	0.0432840434403348	0.192274159910578
GO:0005172	vascular endothelial growth factor receptor binding	3/1163	13/18639	0.230769230769231	3.69845889278391	0.0432840434403348	0.192274159910578
GO:0008417	fucosyltransferase activity	3/1163	13/18639	0.230769230769231	3.69845889278391	0.0432840434403348	0.192274159910578
GO:0017154	semaphorin receptor activity	3/1163	13/18639	0.230769230769231	3.69845889278391	0.0432840434403348	0.192274159910578
GO:0043560	insulin receptor substrate binding	3/1163	13/18639	0.230769230769231	3.69845889278391	0.0432840434403348	0.192274159910578
GO:0051011	microtubule minus-end binding	3/1163	13/18639	0.230769230769231	3.69845889278391	0.0432840434403348	0.192274159910578
GO:0019894	kinesin binding	6/1163	42/18639	0.142857142857143	2.28952217172338	0.0446692352262484	0.196748683075954
GO:0005243	gap junction channel activity	4/1163	22/18639	0.181818181818182	2.91393730946611	0.0448403975382408	0.196748683075954
GO:0061133	endopeptidase activator activity	4/1163	22/18639	0.181818181818182	2.91393730946611	0.0448403975382408	0.196748683075954
GO:0044389	ubiquitin-like protein ligase binding	28/1163	322/18639	0.0869565217391304	1.39362219148379	0.0476252561772424	0.208118497522502
GO:0005158	insulin receptor binding	4/1163	23/18639	0.173913043478261	2.78724438296759	0.0516940457967304	0.224077013030182
GO:0140103	catalytic activity, acting on a glycoprotein	4/1163	23/18639	0.173913043478261	2.78724438296759	0.0516940457967304	0.224077013030182
GO:0070851	growth factor receptor binding	14/1163	139/18639	0.100719424460432	1.61419548797763	0.0519557172906331	0.224306811596107
GO:0019763	immunoglobulin receptor activity	3/1163	14/18639	0.214285714285714	3.43428325758506	0.0526039661657424	0.226197054512692
GO:0098632	cell-cell adhesion mediator activity	7/1163	55/18639	0.127272727272727	2.03975611662628	0.0538469350556488	0.230619343365827
GO:0043014	alpha-tubulin binding	6/1163	44/18639	0.136363636363636	2.18545298209959	0.0541844824753386	0.231144121670591
GO:0001221	transcription coregulator binding	12/1163	115/18639	0.104347826086957	1.67234662978055	0.0550474004100566	0.233897057078304
GO:0016791	phosphatase activity	24/1163	273/18639	0.0879120879120879	1.40893672106054	0.0568971360702824	0.240804808171471
GO:0042393	histone binding	22/1163	247/18639	0.0890688259109312	1.42747536212712	0.0589794170432499	0.244293917651736
GO:0015149	hexose transmembrane transporter activity	4/1163	24/18639	0.166666666666667	2.67110920034394	0.0590850405483268	0.244293917651736
GO:0048027	mRNA 5'-UTR binding	4/1163	24/18639	0.166666666666667	2.67110920034394	0.0590850405483268	0.244293917651736
GO:0050699	WW domain binding	4/1163	24/18639	0.166666666666667	2.67110920034394	0.0590850405483268	0.244293917651736
GO:0055056	D-glucose transmembrane transporter activity	4/1163	24/18639	0.166666666666667	2.67110920034394	0.0590850405483268	0.244293917651736
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	4/1163	24/18639	0.166666666666667	2.67110920034394	0.0590850405483268	0.244293917651736
GO:0032934	sterol binding	8/1163	68/18639	0.117647058823529	1.8854888473016	0.060341314321164	0.248532233315139
GO:0140161	monocarboxylate:sodium symporter activity	3/1163	15/18639	0.2	3.20533104041273	0.0628000033272162	0.256971933758922
GO:0008017	microtubule binding	24/1163	276/18639	0.0869565217391304	1.39362219148379	0.0628684823986944	0.256971933758922
GO:0004709	MAP kinase kinase kinase activity	4/1163	25/18639	0.16	2.56426483233018	0.0670059770823889	0.271816699485162
GO:0120020	cholesterol transfer activity	4/1163	25/18639	0.16	2.56426483233018	0.0670059770823889	0.271816699485162
GO:0061749	forked DNA-dependent helicase activity	6/1163	47/18639	0.127659574468085	2.04595598324217	0.0705886447802118	0.284205217748044
GO:1990518	single-stranded 3'-5' DNA helicase activity	6/1163	47/18639	0.127659574468085	2.04595598324217	0.0705886447802118	0.284205217748044
GO:0032182	ubiquitin-like protein binding	12/1163	120/18639	0.1	1.60266552020636	0.0713123637681415	0.286047727801314
GO:0001540	amyloid-beta binding	9/1163	83/18639	0.108433734939759	1.73783008215148	0.073382915304855	0.289668939833526
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/1163	16/18639	0.1875	3.00499785038693	0.0738318972226847	0.289668939833526
GO:0005521	lamin binding	3/1163	16/18639	0.1875	3.00499785038693	0.0738318972226847	0.289668939833526
GO:0015562	efflux transmembrane transporter activity	3/1163	16/18639	0.1875	3.00499785038693	0.0738318972226847	0.289668939833526
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3/1163	16/18639	0.1875	3.00499785038693	0.0738318972226847	0.289668939833526
GO:0097027	ubiquitin-protein transferase activator activity	3/1163	16/18639	0.1875	3.00499785038693	0.0738318972226847	0.289668939833526
GO:0008143	poly(A) binding	4/1163	26/18639	0.153846153846154	2.46563926185594	0.0754465904038656	0.291089740540152
GO:0015145	monosaccharide transmembrane transporter activity	4/1163	26/18639	0.153846153846154	2.46563926185594	0.0754465904038656	0.291089740540152
GO:0050681	nuclear androgen receptor binding	4/1163	26/18639	0.153846153846154	2.46563926185594	0.0754465904038656	0.291089740540152
GO:0120014	phospholipid transfer activity	4/1163	26/18639	0.153846153846154	2.46563926185594	0.0754465904038656	0.291089740540152
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	23/1163	268/18639	0.0858208955223881	1.37542190166964	0.0755479419634442	0.291089740540152
GO:0009378	four-way junction helicase activity	6/1163	48/18639	0.125	2.00333190025795	0.0766260171888935	0.292102725099505
GO:0036121	double-stranded DNA helicase activity	6/1163	48/18639	0.125	2.00333190025795	0.0766260171888935	0.292102725099505
GO:0043138	3'-5' DNA helicase activity	6/1163	48/18639	0.125	2.00333190025795	0.0766260171888935	0.292102725099505
GO:0030551	cyclic nucleotide binding	5/1163	37/18639	0.135135135135135	2.16576421649508	0.0780902582493443	0.295588125415652
GO:0042805	actinin binding	5/1163	37/18639	0.135135135135135	2.16576421649508	0.0780902582493443	0.295588125415652
GO:0140789	histone phosphatase activity	13/1163	136/18639	0.0955882352941176	1.53195968843255	0.0825126568281868	0.311231951194038
GO:0043539	protein serine/threonine kinase activator activity	8/1163	73/18639	0.10958904109589	1.75634577556862	0.084061552032744	0.3159656238993
GO:0005044	scavenger receptor activity	4/1163	27/18639	0.148148148148148	2.37431928919461	0.0843940163210937	0.316109991446605
GO:0008569	minus-end-directed microtubule motor activity	3/1163	17/18639	0.176470588235294	2.82823327095241	0.0856544492495373	0.316421075406366
GO:0030169	low-density lipoprotein particle binding	3/1163	17/18639	0.176470588235294	2.82823327095241	0.0856544492495373	0.316421075406366
GO:0032183	SUMO binding	3/1163	17/18639	0.176470588235294	2.82823327095241	0.0856544492495373	0.316421075406366
GO:0036041	long-chain fatty acid binding	3/1163	17/18639	0.176470588235294	2.82823327095241	0.0856544492495373	0.316421075406366
GO:0005319	lipid transporter activity	16/1163	178/18639	0.0898876404494382	1.44059822041021	0.0904259197809422	0.332903643029154
GO:0140098	catalytic activity, acting on RNA	31/1163	387/18639	0.0801033591731266	1.28378891799476	0.0919481626367902	0.337352473838053
GO:0046966	nuclear thyroid hormone receptor binding	4/1163	28/18639	0.142857142857143	2.28952217172338	0.0938330531038175	0.340223150834724
GO:0051119	sugar transmembrane transporter activity	4/1163	28/18639	0.142857142857143	2.28952217172338	0.0938330531038175	0.340223150834724
GO:0051393	alpha-actinin binding	4/1163	28/18639	0.142857142857143	2.28952217172338	0.0938330531038175	0.340223150834724
GO:0140767	enzyme-substrate adaptor activity	13/1163	139/18639	0.0935251798561151	1.49889581026494	0.0939965356259656	0.340223150834724
GO:0003725	double-stranded RNA binding	8/1163	75/18639	0.106666666666667	1.70950988822012	0.0948870307939421	0.342293819139221
GO:0004706	JUN kinase kinase kinase activity	3/1163	18/18639	0.166666666666667	2.67110920034394	0.0982186989161658	0.351950337782927
GO:0031690	adrenergic receptor binding	3/1163	18/18639	0.166666666666667	2.67110920034394	0.0982186989161658	0.351950337782927
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	15/1163	167/18639	0.0898203592814371	1.43951992832907	0.0991760197136067	0.354200070405738
GO:0098631	cell adhesion mediator activity	8/1163	76/18639	0.105263157894737	1.68701633705933	0.100583884571491	0.358038661968055
GO:0015144	carbohydrate transmembrane transporter activity	5/1163	40/18639	0.125	2.00333190025795	0.101487372402619	0.360062459844275
GO:0001217	DNA-binding transcription repressor activity	23/1163	278/18639	0.0827338129496403	1.32594629369591	0.102204355779702	0.361413429155195
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	4/1163	29/18639	0.137931034482759	2.21057313131912	0.103746420377147	0.364468633677887
GO:0097472	cyclin-dependent protein kinase activity	4/1163	29/18639	0.137931034482759	2.21057313131912	0.103746420377147	0.364468633677887
GO:0035591	signaling adaptor activity	12/1163	129/18639	0.0930232558139535	1.49085164670359	0.107719186340098	0.377192590604578
GO:0038024	cargo receptor activity	7/1163	65/18639	0.107692307692308	1.72594748329916	0.109409781917813	0.381868557018341
GO:0004864	protein phosphatase inhibitor activity	6/1163	53/18639	0.113207547169811	1.81433832476192	0.110991188565421	0.385316466935166
GO:0015245	fatty acid transmembrane transporter activity	3/1163	19/18639	0.157894736842105	2.53052450558899	0.11147294996915	0.385316466935166
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/1163	19/18639	0.157894736842105	2.53052450558899	0.11147294996915	0.385316466935166
GO:1990782	protein tyrosine kinase binding	11/1163	117/18639	0.094017094017094	1.50677954891197	0.113508258893914	0.388207716657023
GO:0072341	modified amino acid binding	9/1163	91/18639	0.0989010989010989	1.58505381119311	0.113914628031317	0.388207716657023
GO:0033612	receptor serine/threonine kinase binding	4/1163	30/18639	0.133333333333333	2.13688736027515	0.114115012524297	0.388207716657023
GO:0051721	protein phosphatase 2A binding	4/1163	30/18639	0.133333333333333	2.13688736027515	0.114115012524297	0.388207716657023
GO:0070566	adenylyltransferase activity	4/1163	30/18639	0.133333333333333	2.13688736027515	0.114115012524297	0.388207716657023
GO:0019955	cytokine binding	13/1163	144/18639	0.0902777777777778	1.44685081685297	0.115213347085169	0.390707722765162
GO:0051287	NAD binding	6/1163	54/18639	0.111111111111111	1.78073946689596	0.118672167768551	0.399184275334155
GO:0050840	extracellular matrix binding	7/1163	67/18639	0.104477611940299	1.67442666290217	0.123202766126904	0.399184275334155
GO:0140030	modification-dependent protein binding	15/1163	173/18639	0.0867052023121387	1.38959438168182	0.123263220466236	0.399184275334155
GO:0000182	rDNA binding	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0004862	cAMP-dependent protein kinase inhibitor activity	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0004955	prostaglandin receptor activity	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0005522	profilin binding	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0016303	1-phosphatidylinositol-3-kinase activity	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0031434	mitogen-activated protein kinase kinase binding	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0042975	peroxisome proliferator activated receptor binding	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0070097	delta-catenin binding	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0070739	protein-glutamic acid ligase activity	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0070740	tubulin-glutamic acid ligase activity	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0140999	histone H3K4 trimethyltransferase activity	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:1990757	ubiquitin ligase activator activity	2/1163	10/18639	0.2	3.20533104041273	0.125510962849251	0.399184275334155
GO:0099106	ion channel regulator activity	14/1163	160/18639	0.0875	1.40233233018057	0.12626968868465	0.400412729604717
GO:0033192	calmodulin-dependent protein phosphatase activity	8/1163	81/18639	0.0987654320987654	1.58287952612974	0.131839066862825	0.408435149502989
GO:0140791	histone H2AXS140 phosphatase activity	8/1163	81/18639	0.0987654320987654	1.58287952612974	0.131839066862825	0.408435149502989
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	8/1163	81/18639	0.0987654320987654	1.58287952612974	0.131839066862825	0.408435149502989
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	8/1163	81/18639	0.0987654320987654	1.58287952612974	0.131839066862825	0.408435149502989
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	8/1163	81/18639	0.0987654320987654	1.58287952612974	0.131839066862825	0.408435149502989
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	8/1163	81/18639	0.0987654320987654	1.58287952612974	0.131839066862825	0.408435149502989
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	8/1163	81/18639	0.0987654320987654	1.58287952612974	0.131839066862825	0.408435149502989
GO:1990439	MAP kinase serine/threonine phosphatase activity	8/1163	81/18639	0.0987654320987654	1.58287952612974	0.131839066862825	0.408435149502989
GO:0019212	phosphatase inhibitor activity	6/1163	56/18639	0.107142857142857	1.71714162879253	0.134797904994383	0.414571732825623
GO:0051059	NF-kappaB binding	4/1163	32/18639	0.125	2.00333190025795	0.136133787616228	0.414571732825623
GO:0070717	poly-purine tract binding	4/1163	32/18639	0.125	2.00333190025795	0.136133787616228	0.414571732825623
GO:0071813	lipoprotein particle binding	4/1163	32/18639	0.125	2.00333190025795	0.136133787616228	0.414571732825623
GO:0071814	protein-lipid complex binding	4/1163	32/18639	0.125	2.00333190025795	0.136133787616228	0.414571732825623
GO:0120015	sterol transfer activity	4/1163	32/18639	0.125	2.00333190025795	0.136133787616228	0.414571732825623
GO:0008168	methyltransferase activity	17/1163	204/18639	0.0833333333333333	1.33555460017197	0.137255062703514	0.416107578899902
GO:0001223	transcription coactivator binding	5/1163	44/18639	0.113636363636364	1.82121081841632	0.137412270241363	0.416107578899902
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	8/1163	82/18639	0.0975609756097561	1.5635761172745	0.138626796337877	0.417433630429182
GO:0033549	MAP kinase phosphatase activity	8/1163	82/18639	0.0975609756097561	1.5635761172745	0.138626796337877	0.417433630429182
GO:0001846	opsonin binding	3/1163	21/18639	0.142857142857143	2.28952217172338	0.139836205647085	0.418729585154921
GO:0035613	RNA stem-loop binding	3/1163	21/18639	0.142857142857143	2.28952217172338	0.139836205647085	0.418729585154921
GO:0004620	phospholipase activity	10/1163	109/18639	0.0917431192660551	1.47033533963886	0.142449400850327	0.425369738650281
GO:0016504	peptidase activator activity	6/1163	57/18639	0.105263157894737	1.68701633705933	0.143228827707776	0.425788755398034
GO:0008028	monocarboxylic acid transmembrane transporter activity	7/1163	70/18639	0.1	1.60266552020636	0.145455560451156	0.425788755398034
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	8/1163	83/18639	0.0963855421686747	1.54473785080131	0.145586143648067	0.425788755398034
GO:0001851	complement component C3b binding	2/1163	11/18639	0.181818181818182	2.91393730946611	0.147313270087664	0.425788755398034
GO:0002162	dystroglycan binding	2/1163	11/18639	0.181818181818182	2.91393730946611	0.147313270087664	0.425788755398034
GO:0004954	prostanoid receptor activity	2/1163	11/18639	0.181818181818182	2.91393730946611	0.147313270087664	0.425788755398034
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/1163	11/18639	0.181818181818182	2.91393730946611	0.147313270087664	0.425788755398034
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/1163	11/18639	0.181818181818182	2.91393730946611	0.147313270087664	0.425788755398034
GO:0034056	estrogen response element binding	2/1163	11/18639	0.181818181818182	2.91393730946611	0.147313270087664	0.425788755398034
GO:0070697	activin receptor binding	2/1163	11/18639	0.181818181818182	2.91393730946611	0.147313270087664	0.425788755398034
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/1163	11/18639	0.181818181818182	2.91393730946611	0.147313270087664	0.425788755398034
GO:0030296	protein tyrosine kinase activator activity	4/1163	33/18639	0.121212121212121	1.94262487297741	0.147738796059039	0.425788755398034
GO:0140311	protein sequestering activity	4/1163	33/18639	0.121212121212121	1.94262487297741	0.147738796059039	0.425788755398034
GO:0017116	single-stranded DNA helicase activity	6/1163	58/18639	0.103448275862069	1.65792984848934	0.151894992660634	0.436596569813321
GO:0017018	myosin phosphatase activity	8/1163	84/18639	0.0952380952380952	1.52634811448225	0.152713407783941	0.436614131297171
GO:0051117	ATPase binding	8/1163	84/18639	0.0952380952380952	1.52634811448225	0.152713407783941	0.436614131297171
GO:0016881	acid-amino acid ligase activity	3/1163	22/18639	0.136363636363636	2.18545298209959	0.154835543769534	0.440339178709654
GO:0140517	protein-RNA adaptor activity	3/1163	22/18639	0.136363636363636	2.18545298209959	0.154835543769534	0.440339178709654
GO:0008376	acetylgalactosaminyltransferase activity	4/1163	34/18639	0.117647058823529	1.8854888473016	0.159709119639168	0.44826972222482
GO:0015020	glucuronosyltransferase activity	4/1163	34/18639	0.117647058823529	1.8854888473016	0.159709119639168	0.44826972222482
GO:0019825	oxygen binding	4/1163	34/18639	0.117647058823529	1.8854888473016	0.159709119639168	0.44826972222482
GO:0030332	cyclin binding	4/1163	34/18639	0.117647058823529	1.8854888473016	0.159709119639168	0.44826972222482
GO:0090482	vitamin transmembrane transporter activity	4/1163	34/18639	0.117647058823529	1.8854888473016	0.159709119639168	0.44826972222482
GO:0016247	channel regulator activity	14/1163	168/18639	0.0833333333333333	1.33555460017197	0.165402824074713	0.46304176010499
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	8/1163	86/18639	0.0930232558139535	1.49085164670359	0.167455554227921	0.467570703363674
GO:0008603	cAMP-dependent protein kinase regulator activity	2/1163	12/18639	0.166666666666667	2.67110920034394	0.169801083625709	0.468234721484307
GO:0015166	polyol transmembrane transporter activity	2/1163	12/18639	0.166666666666667	2.67110920034394	0.169801083625709	0.468234721484307
GO:0042301	phosphate ion binding	2/1163	12/18639	0.166666666666667	2.67110920034394	0.169801083625709	0.468234721484307
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/1163	12/18639	0.166666666666667	2.67110920034394	0.169801083625709	0.468234721484307
GO:0017134	fibroblast growth factor binding	3/1163	23/18639	0.130434782608696	2.09043328722569	0.170306768465455	0.468234721484307
GO:0070577	lysine-acetylated histone binding	3/1163	23/18639	0.130434782608696	2.09043328722569	0.170306768465455	0.468234721484307
GO:0004386	helicase activity	13/1163	155/18639	0.0838709677419355	1.3441710814634	0.170772131172019	0.468316431147757
GO:0043130	ubiquitin binding	9/1163	100/18639	0.09	1.44239896818573	0.171502464804184	0.469122518230273
GO:0043015	gamma-tubulin binding	4/1163	35/18639	0.114285714285714	1.8316177373787	0.172020005571816	0.469343923831731
GO:0141108	transporter regulator activity	14/1163	170/18639	0.0823529411764706	1.31984219311112	0.176063423789534	0.479159950819617
GO:0003678	DNA helicase activity	7/1163	74/18639	0.0945945945945946	1.51603495154656	0.177833221795047	0.481020296181131
GO:0038187	pattern recognition receptor activity	5/1163	48/18639	0.104166666666667	1.66944325021496	0.178089374772177	0.481020296181131
GO:0140693	molecular condensate scaffold activity	5/1163	48/18639	0.104166666666667	1.66944325021496	0.178089374772177	0.481020296181131
GO:0055106	ubiquitin-protein transferase regulator activity	4/1163	36/18639	0.111111111111111	1.78073946689596	0.184646186733001	0.497480327664101
GO:0035035	histone acetyltransferase binding	3/1163	24/18639	0.125	2.00333190025795	0.18619558673933	0.499152757468279
GO:0140033	acetylation-dependent protein binding	3/1163	24/18639	0.125	2.00333190025795	0.18619558673933	0.499152757468279
GO:0016741	transferase activity, transferring one-carbon groups	17/1163	215/18639	0.0790697674418605	1.26722389969805	0.187895994936542	0.502458195414882
GO:0035254	glutamate receptor binding	5/1163	49/18639	0.102040816326531	1.63537297980241	0.188901123325664	0.503892574628013
GO:0000287	magnesium ion binding	18/1163	230/18639	0.0782608695652174	1.25425997233541	0.19082864002073	0.507774227777934
GO:0019855	calcium channel inhibitor activity	2/1163	13/18639	0.153846153846154	2.46563926185594	0.192804181841231	0.509132838937425
GO:0030955	potassium ion binding	2/1163	13/18639	0.153846153846154	2.46563926185594	0.192804181841231	0.509132838937425
GO:0070700	BMP receptor binding	2/1163	13/18639	0.153846153846154	2.46563926185594	0.192804181841231	0.509132838937425
GO:0004722	protein serine/threonine phosphatase activity	9/1163	103/18639	0.087378640776699	1.40038734775313	0.193233672824623	0.509132838937425
GO:0019213	deacetylase activity	4/1163	37/18639	0.108108108108108	1.73261137319607	0.197562056852232	0.517998075893049
GO:0022829	wide pore channel activity	4/1163	37/18639	0.108108108108108	1.73261137319607	0.197562056852232	0.517998075893049
GO:0001848	complement binding	3/1163	25/18639	0.12	1.92319862424764	0.202448715328913	0.529519145933288
GO:0000146	microfilament motor activity	4/1163	38/18639	0.105263157894737	1.68701633705933	0.210741832480598	0.547064827837913
GO:0043531	ADP binding	4/1163	38/18639	0.105263157894737	1.68701633705933	0.210741832480598	0.547064827837913
GO:0016597	amino acid binding	5/1163	51/18639	0.0980392156862745	1.57124070608467	0.211192468421148	0.547064827837913
GO:0016830	carbon-carbon lyase activity	5/1163	51/18639	0.0980392156862745	1.57124070608467	0.211192468421148	0.547064827837913
GO:0004065	arylsulfatase activity	2/1163	14/18639	0.142857142857143	2.28952217172338	0.216170884453813	0.551980286907004
GO:0008195	phosphatidate phosphatase activity	2/1163	14/18639	0.142857142857143	2.28952217172338	0.216170884453813	0.551980286907004
GO:0019992	diacylglycerol binding	2/1163	14/18639	0.142857142857143	2.28952217172338	0.216170884453813	0.551980286907004
GO:0044548	S100 protein binding	2/1163	14/18639	0.142857142857143	2.28952217172338	0.216170884453813	0.551980286907004
GO:0071933	Arp2/3 complex binding	2/1163	14/18639	0.142857142857143	2.28952217172338	0.216170884453813	0.551980286907004
GO:1990825	sequence-specific mRNA binding	2/1163	14/18639	0.142857142857143	2.28952217172338	0.216170884453813	0.551980286907004
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/1163	26/18639	0.115384615384615	1.84922944639196	0.219014209884354	0.555283668928492
GO:0008157	protein phosphatase 1 binding	3/1163	26/18639	0.115384615384615	1.84922944639196	0.219014209884354	0.555283668928492
GO:0019865	immunoglobulin binding	3/1163	26/18639	0.115384615384615	1.84922944639196	0.219014209884354	0.555283668928492
GO:0030159	signaling receptor complex adaptor activity	5/1163	52/18639	0.0961538461538462	1.54102453865996	0.222641343590832	0.563151633788576
GO:0002020	protease binding	11/1163	136/18639	0.0808823529411765	1.29627358251985	0.228947264026965	0.576619429472418
GO:0016757	glycosyltransferase activity	20/1163	267/18639	0.0749063670411985	1.20049851700851	0.2292294295423	0.576619429472418
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	10/1163	122/18639	0.0819672131147541	1.31366026246423	0.230676698352209	0.576619429472418
GO:0042562	hormone binding	8/1163	94/18639	0.0851063829787234	1.36397065549478	0.232233185576263	0.576619429472418
GO:0005246	calcium channel regulator activity	5/1163	53/18639	0.0943396226415094	1.51194860396827	0.234271568072646	0.576619429472418
GO:0008146	sulfotransferase activity	5/1163	53/18639	0.0943396226415094	1.51194860396827	0.234271568072646	0.576619429472418
GO:0017046	peptide hormone binding	5/1163	53/18639	0.0943396226415094	1.51194860396827	0.234271568072646	0.576619429472418
GO:0008266	poly(U) RNA binding	3/1163	27/18639	0.111111111111111	1.78073946689596	0.235841734079762	0.576619429472418
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	3/1163	27/18639	0.111111111111111	1.78073946689596	0.235841734079762	0.576619429472418
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	3/1163	27/18639	0.111111111111111	1.78073946689596	0.235841734079762	0.576619429472418
GO:0004559	alpha-mannosidase activity	2/1163	15/18639	0.133333333333333	2.13688736027515	0.239766404627136	0.576619429472418
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/1163	15/18639	0.133333333333333	2.13688736027515	0.239766404627136	0.576619429472418
GO:0004953	icosanoid receptor activity	2/1163	15/18639	0.133333333333333	2.13688736027515	0.239766404627136	0.576619429472418
GO:0010181	FMN binding	2/1163	15/18639	0.133333333333333	2.13688736027515	0.239766404627136	0.576619429472418
GO:0015929	hexosaminidase activity	2/1163	15/18639	0.133333333333333	2.13688736027515	0.239766404627136	0.576619429472418
GO:0034483	heparan sulfate sulfotransferase activity	2/1163	15/18639	0.133333333333333	2.13688736027515	0.239766404627136	0.576619429472418
GO:0050700	CARD domain binding	2/1163	15/18639	0.133333333333333	2.13688736027515	0.239766404627136	0.576619429472418
GO:0051371	muscle alpha-actinin binding	2/1163	15/18639	0.133333333333333	2.13688736027515	0.239766404627136	0.576619429472418
GO:0061578	K63-linked deubiquitinase activity	2/1163	15/18639	0.133333333333333	2.13688736027515	0.239766404627136	0.576619429472418
GO:0120283	protein serine/threonine kinase binding	2/1163	15/18639	0.133333333333333	2.13688736027515	0.239766404627136	0.576619429472418
GO:0141050	histone H3K deacetylase activity	2/1163	15/18639	0.133333333333333	2.13688736027515	0.239766404627136	0.576619429472418
GO:0141051	histone H4K deacetylase activity	2/1163	15/18639	0.133333333333333	2.13688736027515	0.239766404627136	0.576619429472418
GO:0140463	chromatin-protein adaptor activity	5/1163	54/18639	0.0925925925925926	1.48394955574663	0.246067425246533	0.590451969062552
GO:0016758	hexosyltransferase activity	15/1163	197/18639	0.0761421319796954	1.2203036955886	0.248795119938227	0.595667603415577
GO:0030145	manganese ion binding	6/1163	68/18639	0.0882352941176471	1.4141166354762	0.249502168904237	0.596032959049011
GO:0019789	SUMO transferase activity	3/1163	28/18639	0.107142857142857	1.71714162879253	0.252882775796875	0.597470294465144
GO:0045499	chemorepellent activity	3/1163	28/18639	0.107142857142857	1.71714162879253	0.252882775796875	0.597470294465144
GO:0050698	proteoglycan sulfotransferase activity	3/1163	28/18639	0.107142857142857	1.71714162879253	0.252882775796875	0.597470294465144
GO:0051019	mitogen-activated protein kinase binding	3/1163	28/18639	0.107142857142857	1.71714162879253	0.252882775796875	0.597470294465144
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	3/1163	28/18639	0.107142857142857	1.71714162879253	0.252882775796875	0.597470294465144
GO:0005506	iron ion binding	12/1163	154/18639	0.0779220779220779	1.24883027548548	0.254095777560912	0.599019651048203
GO:1902936	phosphatidylinositol bisphosphate binding	9/1163	111/18639	0.0810810810810811	1.29945852989705	0.256282990578196	0.602853861863372
GO:0140313	molecular sequestering activity	5/1163	55/18639	0.0909090909090909	1.45696865473306	0.258013172634582	0.605195906678564
GO:0002039	p53 binding	6/1163	69/18639	0.0869565217391304	1.39362219148379	0.260137081037823	0.605195906678564
GO:0003688	DNA replication origin binding	2/1163	16/18639	0.125	2.00333190025795	0.263471334256343	0.605195906678564
GO:0005159	insulin-like growth factor receptor binding	2/1163	16/18639	0.125	2.00333190025795	0.263471334256343	0.605195906678564
GO:0015378	sodium:chloride symporter activity	2/1163	16/18639	0.125	2.00333190025795	0.263471334256343	0.605195906678564
GO:0015923	mannosidase activity	2/1163	16/18639	0.125	2.00333190025795	0.263471334256343	0.605195906678564
GO:0030275	LRR domain binding	2/1163	16/18639	0.125	2.00333190025795	0.263471334256343	0.605195906678564
GO:0034450	ubiquitin-ubiquitin ligase activity	2/1163	16/18639	0.125	2.00333190025795	0.263471334256343	0.605195906678564
GO:0043023	ribosomal large subunit binding	2/1163	16/18639	0.125	2.00333190025795	0.263471334256343	0.605195906678564
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	2/1163	16/18639	0.125	2.00333190025795	0.263471334256343	0.605195906678564
GO:0140328	floppase activity	2/1163	16/18639	0.125	2.00333190025795	0.263471334256343	0.605195906678564
GO:0005200	structural constituent of cytoskeleton	9/1163	112/18639	0.0803571428571429	1.2878562215944	0.264604901933807	0.606503773089217
GO:0004725	protein tyrosine phosphatase activity	8/1163	98/18639	0.0816326530612245	1.30829838384193	0.267501813551792	0.611839254400375
GO:0004181	metallocarboxypeptidase activity	3/1163	29/18639	0.103448275862069	1.65792984848934	0.270090816806843	0.615148481773721
GO:0170055	lipid transmembrane transporter activity	5/1163	56/18639	0.0892857142857143	1.43095135732711	0.270093100834601	0.615148481773721
GO:0004712	protein serine/threonine/tyrosine kinase activity	4/1163	43/18639	0.0930232558139535	1.49085164670359	0.279702149376606	0.633964854566324
GO:0008200	ion channel inhibitor activity	4/1163	43/18639	0.0930232558139535	1.49085164670359	0.279702149376606	0.633964854566324
GO:0033218	amide binding	18/1163	247/18639	0.0728744939271255	1.16793438719492	0.281280971379966	0.633964854566324
GO:0004601	peroxidase activity	5/1163	57/18639	0.087719298245614	1.40584694754944	0.282291588635258	0.633964854566324
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/1163	17/18639	0.117647058823529	1.8854888473016	0.28718025225725	0.633964854566324
GO:0008484	sulfuric ester hydrolase activity	2/1163	17/18639	0.117647058823529	1.8854888473016	0.28718025225725	0.633964854566324
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/1163	17/18639	0.117647058823529	1.8854888473016	0.28718025225725	0.633964854566324
GO:0015278	intracellularly gated calcium channel activity	2/1163	17/18639	0.117647058823529	1.8854888473016	0.28718025225725	0.633964854566324
GO:0019198	transmembrane receptor protein phosphatase activity	2/1163	17/18639	0.117647058823529	1.8854888473016	0.28718025225725	0.633964854566324
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/1163	17/18639	0.117647058823529	1.8854888473016	0.28718025225725	0.633964854566324
GO:0070402	NADPH binding	2/1163	17/18639	0.117647058823529	1.8854888473016	0.28718025225725	0.633964854566324
GO:0070403	NAD+ binding	2/1163	17/18639	0.117647058823529	1.8854888473016	0.28718025225725	0.633964854566324
GO:0001965	G-protein alpha-subunit binding	3/1163	30/18639	0.1	1.60266552020636	0.287421461727126	0.633964854566324
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/1163	30/18639	0.1	1.60266552020636	0.287421461727126	0.633964854566324
GO:0008187	poly-pyrimidine tract binding	3/1163	30/18639	0.1	1.60266552020636	0.287421461727126	0.633964854566324
GO:0001216	DNA-binding transcription activator activity	34/1163	491/18639	0.0692464358452139	1.10978875126306	0.28779055723569	0.633964854566324
GO:0016209	antioxidant activity	7/1163	86/18639	0.0813953488372093	1.30449519086564	0.28952967802276	0.636491623465168
GO:0016298	lipase activity	10/1163	130/18639	0.0769230769230769	1.23281963092797	0.29316991475926	0.640924893685375
GO:0004857	enzyme inhibitor activity	29/1163	416/18639	0.0697115384615385	1.11724279052847	0.293881823147791	0.640924893685375
GO:0001046	core promoter sequence-specific DNA binding	4/1163	44/18639	0.0909090909090909	1.45696865473306	0.29393113729013	0.640924893685375
GO:0016248	channel inhibitor activity	4/1163	44/18639	0.0909090909090909	1.45696865473306	0.29393113729013	0.640924893685375
GO:0008194	UDP-glycosyltransferase activity	11/1163	145/18639	0.0758620689655172	1.21581522222552	0.295405621892253	0.642836120514519
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	5/1163	59/18639	0.0847457627118644	1.35819111881895	0.306982502981392	0.661604910706439
GO:0051539	4 iron, 4 sulfur cluster binding	4/1163	45/18639	0.0888888888888889	1.42459157351677	0.308249504886257	0.661604910706439
GO:0141110	transporter inhibitor activity	4/1163	45/18639	0.0888888888888889	1.42459157351677	0.308249504886257	0.661604910706439
GO:0004197	cysteine-type endopeptidase activity	7/1163	88/18639	0.0795454545454545	1.27484757289143	0.309633150755319	0.661604910706439
GO:0000400	four-way junction DNA binding	2/1163	18/18639	0.111111111111111	1.78073946689596	0.310800446424885	0.661604910706439
GO:0015373	monoatomic anion:sodium symporter activity	2/1163	18/18639	0.111111111111111	1.78073946689596	0.310800446424885	0.661604910706439
GO:0017075	syntaxin-1 binding	2/1163	18/18639	0.111111111111111	1.78073946689596	0.310800446424885	0.661604910706439
GO:0030228	lipoprotein particle receptor activity	2/1163	18/18639	0.111111111111111	1.78073946689596	0.310800446424885	0.661604910706439
GO:0034185	apolipoprotein binding	2/1163	18/18639	0.111111111111111	1.78073946689596	0.310800446424885	0.661604910706439
GO:0070628	proteasome binding	2/1163	18/18639	0.111111111111111	1.78073946689596	0.310800446424885	0.661604910706439
GO:1901611	phosphatidylglycerol binding	2/1163	18/18639	0.111111111111111	1.78073946689596	0.310800446424885	0.661604910706439
GO:0035064	methylated histone binding	6/1163	74/18639	0.0810810810810811	1.29945852989705	0.314841613827543	0.668882875226499
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	7/1163	89/18639	0.0786516853932584	1.26052344285894	0.319784194801087	0.676708679943246
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	7/1163	89/18639	0.0786516853932584	1.26052344285894	0.319784194801087	0.676708679943246
GO:0043425	bHLH transcription factor binding	3/1163	32/18639	0.09375	1.50249892519347	0.322284125629488	0.67962248480741
GO:0030276	clathrin binding	4/1163	46/18639	0.0869565217391304	1.39362219148379	0.322634372069131	0.67962248480741
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	33/1163	484/18639	0.0681818181818182	1.09272649104979	0.323057757894499	0.67962248480741
GO:0140793	histone H2AXY142 phosphatase activity	7/1163	90/18639	0.0777777777777778	1.24651762682717	0.329990726254182	0.69099912622111
GO:0015026	coreceptor activity	5/1163	61/18639	0.0819672131147541	1.31366026246423	0.331964562900443	0.69099912622111
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/1163	19/18639	0.105263157894737	1.68701633705933	0.33425074012556	0.69099912622111
GO:0008381	mechanosensitive monoatomic ion channel activity	2/1163	19/18639	0.105263157894737	1.68701633705933	0.33425074012556	0.69099912622111
GO:0008574	plus-end-directed microtubule motor activity	2/1163	19/18639	0.105263157894737	1.68701633705933	0.33425074012556	0.69099912622111
GO:0031420	alkali metal ion binding	2/1163	19/18639	0.105263157894737	1.68701633705933	0.33425074012556	0.69099912622111
GO:0042577	lipid phosphatase activity	2/1163	19/18639	0.105263157894737	1.68701633705933	0.33425074012556	0.69099912622111
GO:0042834	peptidoglycan binding	2/1163	19/18639	0.105263157894737	1.68701633705933	0.33425074012556	0.69099912622111
GO:0050145	nucleoside monophosphate kinase activity	2/1163	19/18639	0.105263157894737	1.68701633705933	0.33425074012556	0.69099912622111
GO:0140359	ABC-type transporter activity	4/1163	47/18639	0.0851063829787234	1.36397065549478	0.337063590398919	0.694499749379958
GO:0140034	methylation-dependent protein binding	6/1163	76/18639	0.0789473684210526	1.2652622527945	0.337236157373338	0.694499749379958
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	7/1163	91/18639	0.0769230769230769	1.23281963092797	0.340244775465363	0.699355896033012
GO:0000149	SNARE binding	8/1163	106/18639	0.0754716981132075	1.20955888317461	0.341866520287971	0.701348300209101
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	9/1163	122/18639	0.0737704918032787	1.18229423621781	0.351494637597724	0.719727115081054
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	3/1163	34/18639	0.0882352941176471	1.4141166354762	0.357160872033053	0.72095674843015
GO:0016831	carboxy-lyase activity	3/1163	34/18639	0.0882352941176471	1.4141166354762	0.357160872033053	0.72095674843015
GO:0051427	hormone receptor binding	3/1163	34/18639	0.0882352941176471	1.4141166354762	0.357160872033053	0.72095674843015
GO:0052866	phosphatidylinositol phosphate phosphatase activity	3/1163	34/18639	0.0882352941176471	1.4141166354762	0.357160872033053	0.72095674843015
GO:0016505	peptidase activator activity involved in apoptotic process	2/1163	20/18639	0.1	1.60266552020636	0.357460415733274	0.72095674843015
GO:0030742	GTP-dependent protein binding	2/1163	20/18639	0.1	1.60266552020636	0.357460415733274	0.72095674843015
GO:0140664	ATP-dependent DNA damage sensor activity	2/1163	20/18639	0.1	1.60266552020636	0.357460415733274	0.72095674843015
GO:0140939	histone H4 methyltransferase activity	2/1163	20/18639	0.1	1.60266552020636	0.357460415733274	0.72095674843015
GO:0005343	organic acid:sodium symporter activity	3/1163	35/18639	0.0857142857142857	1.37371330303403	0.374517828263793	0.75164677273969
GO:0140566	histone reader activity	3/1163	35/18639	0.0857142857142857	1.37371330303403	0.374517828263793	0.75164677273969
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	2/1163	21/18639	0.0952380952380952	1.52634811448225	0.380368227321294	0.75164677273969
GO:0005123	death receptor binding	2/1163	21/18639	0.0952380952380952	1.52634811448225	0.380368227321294	0.75164677273969
GO:0010314	phosphatidylinositol-5-phosphate binding	2/1163	21/18639	0.0952380952380952	1.52634811448225	0.380368227321294	0.75164677273969
GO:0015174	basic amino acid transmembrane transporter activity	2/1163	21/18639	0.0952380952380952	1.52634811448225	0.380368227321294	0.75164677273969
GO:0051010	microtubule plus-end binding	2/1163	21/18639	0.0952380952380952	1.52634811448225	0.380368227321294	0.75164677273969
GO:0051428	peptide hormone receptor binding	2/1163	21/18639	0.0952380952380952	1.52634811448225	0.380368227321294	0.75164677273969
GO:0070182	DNA polymerase binding	2/1163	21/18639	0.0952380952380952	1.52634811448225	0.380368227321294	0.75164677273969
GO:0072542	protein phosphatase activator activity	2/1163	21/18639	0.0952380952380952	1.52634811448225	0.380368227321294	0.75164677273969
GO:0140312	cargo adaptor activity	2/1163	21/18639	0.0952380952380952	1.52634811448225	0.380368227321294	0.75164677273969
GO:0031406	carboxylic acid binding	13/1163	187/18639	0.0695187165775401	1.11415250067822	0.384617999013364	0.758650181540122
GO:0016409	palmitoyltransferase activity	3/1163	36/18639	0.0833333333333333	1.33555460017197	0.391778886584775	0.761231296752558
GO:0030971	receptor tyrosine kinase binding	6/1163	81/18639	0.0740740740740741	1.18715964459731	0.393774735163665	0.761231296752558
GO:0019783	ubiquitin-like protein peptidase activity	9/1163	127/18639	0.0708661417322835	1.13574721904388	0.396423824836323	0.761231296752558
GO:0140658	ATP-dependent chromatin remodeler activity	11/1163	158/18639	0.069620253164557	1.11577979254873	0.398537221146025	0.761231296752558
GO:0043177	organic acid binding	13/1163	189/18639	0.0687830687830688	1.10236252712607	0.399380521705802	0.761231296752558
GO:0004407	histone deacetylase activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0008093	cytoskeletal anchor activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0008970	phospholipase A1 activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0015377	chloride:monoatomic cation symporter activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0032931	histone H3K56 acetyltransferase activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0033558	protein lysine deacetylase activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0043992	histone H3K9 acetyltransferase activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0043993	histone H3K18 acetyltransferase activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0043994	histone H3K23 acetyltransferase activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0043999	histone H2AK5 acetyltransferase activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0044012	histone H2AK9 acetyltransferase activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0044014	histone H2BK5 acetyltransferase activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0044015	histone H2BK12 acetyltransferase activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0044016	histone H3K4 acetyltransferase activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0044017	histone H3K27 acetyltransferase activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0044018	histone H3K36 acetyltransferase activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0046972	histone H4K16 acetyltransferase activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0070034	telomerase RNA binding	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0140908	histone H3K122 acetyltransferase activity	2/1163	22/18639	0.0909090909090909	1.45696865473306	0.40292149567647	0.761231296752558
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	9/1163	128/18639	0.0703125	1.1268741938951	0.405448071189768	0.764660836015791
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	5/1163	67/18639	0.0746268656716418	1.19601904493012	0.407514970561091	0.767212948079111
GO:0023023	MHC protein complex binding	3/1163	37/18639	0.0810810810810811	1.29945852989705	0.408915665678822	0.76761458942631
GO:0005080	protein kinase C binding	4/1163	52/18639	0.0769230769230769	1.23281963092797	0.409156427666303	0.76761458942631
GO:0003777	microtubule motor activity	5/1163	68/18639	0.0735294117647059	1.1784305295635	0.420055669105285	0.782458775962166
GO:1990841	promoter-specific chromatin binding	5/1163	68/18639	0.0735294117647059	1.1784305295635	0.420055669105285	0.782458775962166
GO:0005544	calcium-dependent phospholipid binding	4/1163	53/18639	0.0754716981132075	1.20955888317461	0.423432742735174	0.782458775962166
GO:0016798	hydrolase activity, acting on glycosyl bonds	9/1163	130/18639	0.0692307692307692	1.10953766783517	0.423496451452312	0.782458775962166
GO:0003887	DNA-directed DNA polymerase activity	2/1163	23/18639	0.0869565217391304	1.39362219148379	0.425075279220377	0.782458775962166
GO:0005283	amino acid:sodium symporter activity	2/1163	23/18639	0.0869565217391304	1.39362219148379	0.425075279220377	0.782458775962166
GO:0031681	G-protein beta-subunit binding	2/1163	23/18639	0.0869565217391304	1.39362219148379	0.425075279220377	0.782458775962166
GO:0042171	lysophosphatidic acid acyltransferase activity	2/1163	23/18639	0.0869565217391304	1.39362219148379	0.425075279220377	0.782458775962166
GO:0043274	phospholipase binding	2/1163	23/18639	0.0869565217391304	1.39362219148379	0.425075279220377	0.782458775962166
GO:0044013	histone H2B acetyltransferase activity	2/1163	23/18639	0.0869565217391304	1.39362219148379	0.425075279220377	0.782458775962166
GO:0071617	lysophospholipid acyltransferase activity	2/1163	23/18639	0.0869565217391304	1.39362219148379	0.425075279220377	0.782458775962166
GO:0042162	telomeric DNA binding	3/1163	38/18639	0.0789473684210526	1.2652622527945	0.42590199423867	0.782640416763368
GO:0003925	G protein activity	4/1163	54/18639	0.0740740740740741	1.18715964459731	0.437621968134264	0.801437164811472
GO:0050661	NADP binding	4/1163	54/18639	0.0740740740740741	1.18715964459731	0.437621968134264	0.801437164811472
GO:0008094	ATP-dependent activity, acting on DNA	14/1163	210/18639	0.0666666666666667	1.06844368013758	0.438655171437649	0.801963111046722
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	9/1163	132/18639	0.0681818181818182	1.09272649104979	0.441513781582279	0.804205130176553
GO:0000217	DNA secondary structure binding	3/1163	39/18639	0.0769230769230769	1.23281963092797	0.44271385193997	0.804205130176553
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	3/1163	39/18639	0.0769230769230769	1.23281963092797	0.44271385193997	0.804205130176553
GO:0016782	transferase activity, transferring sulphur-containing groups	5/1163	70/18639	0.0714285714285714	1.14476108586169	0.444984757659997	0.804205130176553
GO:0030215	semaphorin receptor binding	2/1163	24/18639	0.0833333333333333	1.33555460017197	0.446791614900472	0.804205130176553
GO:0043998	histone H2A acetyltransferase activity	2/1163	24/18639	0.0833333333333333	1.33555460017197	0.446791614900472	0.804205130176553
GO:0140612	DNA damage sensor activity	2/1163	24/18639	0.0833333333333333	1.33555460017197	0.446791614900472	0.804205130176553
GO:0004177	aminopeptidase activity	3/1163	40/18639	0.075	1.20199914015477	0.4593293025853	0.804205130176553
GO:0019842	vitamin binding	10/1163	150/18639	0.0666666666666667	1.06844368013758	0.461492234571055	0.804205130176553
GO:0008139	nuclear localization sequence binding	2/1163	25/18639	0.08	1.28213241616509	0.468038823558868	0.804205130176553
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/1163	25/18639	0.08	1.28213241616509	0.468038823558868	0.804205130176553
GO:0015662	P-type ion transporter activity	2/1163	25/18639	0.08	1.28213241616509	0.468038823558868	0.804205130176553
GO:0017025	TBP-class protein binding	2/1163	25/18639	0.08	1.28213241616509	0.468038823558868	0.804205130176553
GO:0017056	structural constituent of nuclear pore	2/1163	25/18639	0.08	1.28213241616509	0.468038823558868	0.804205130176553
GO:0019211	phosphatase activator activity	2/1163	25/18639	0.08	1.28213241616509	0.468038823558868	0.804205130176553
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/1163	25/18639	0.08	1.28213241616509	0.468038823558868	0.804205130176553
GO:0019707	protein-cysteine S-acyltransferase activity	2/1163	25/18639	0.08	1.28213241616509	0.468038823558868	0.804205130176553
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/1163	25/18639	0.08	1.28213241616509	0.468038823558868	0.804205130176553
GO:0140358	P-type transmembrane transporter activity	2/1163	25/18639	0.08	1.28213241616509	0.468038823558868	0.804205130176553
GO:0005518	collagen binding	5/1163	72/18639	0.0694444444444444	1.11296216680997	0.4696389959411	0.804205130176553
GO:0001094	TFIID-class transcription factor complex binding	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0004935	adrenergic receptor activity	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0005131	growth hormone receptor binding	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0008239	dipeptidyl-peptidase activity	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0008401	retinoic acid 4-hydroxylase activity	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0008519	ammonium channel activity	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0015203	polyamine transmembrane transporter activity	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0015279	store-operated calcium channel activity	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0015643	toxic substance binding	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0016868	intramolecular phosphotransferase activity	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0019911	structural constituent of myelin sheath	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0031419	cobalamin binding	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0035256	G protein-coupled glutamate receptor binding	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0043121	neurotrophin binding	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0043422	protein kinase B binding	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0045322	unmethylated CpG binding	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0050815	phosphoserine residue binding	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0051880	G-quadruplex DNA binding	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0070513	death domain binding	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0140135	mechanosensitive monoatomic cation channel activity	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0141109	transporter activator activity	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:1905394	retromer complex binding	1/1163	10/18639	0.1	1.60266552020636	0.475042100150801	0.804205130176553
GO:0046906	tetrapyrrole binding	10/1163	152/18639	0.0657894736842105	1.05438521066208	0.478369571954776	0.804711494697053
GO:0008237	metallopeptidase activity	12/1163	184/18639	0.0652173913043478	1.04521664361285	0.480016121330654	0.804711494697053
GO:0003727	single-stranded RNA binding	6/1163	89/18639	0.0674157303370786	1.08044866530766	0.483423916888292	0.804711494697053
GO:0003774	cytoskeletal motor activity	10/1163	153/18639	0.065359477124183	1.04749380405645	0.486767547903166	0.804711494697053
GO:0061775	cohesin loader activity	10/1163	153/18639	0.065359477124183	1.04749380405645	0.486767547903166	0.804711494697053
GO:0008198	ferrous iron binding	2/1163	26/18639	0.0769230769230769	1.23281963092797	0.488790874698411	0.804711494697053
GO:0030507	spectrin binding	2/1163	26/18639	0.0769230769230769	1.23281963092797	0.488790874698411	0.804711494697053
GO:0050750	low-density lipoprotein particle receptor binding	2/1163	26/18639	0.0769230769230769	1.23281963092797	0.488790874698411	0.804711494697053
GO:0097602	cullin family protein binding	2/1163	26/18639	0.0769230769230769	1.23281963092797	0.488790874698411	0.804711494697053
GO:0008307	structural constituent of muscle	3/1163	42/18639	0.0714285714285714	1.14476108586169	0.491893215326804	0.804711494697053
GO:0035198	miRNA binding	3/1163	42/18639	0.0714285714285714	1.14476108586169	0.491893215326804	0.804711494697053
GO:0061980	regulatory RNA binding	4/1163	58/18639	0.0689655172413793	1.10528656565956	0.493218251769106	0.804711494697053
GO:0048029	monosaccharide binding	5/1163	74/18639	0.0675675675675676	1.08288210824754	0.493939164965312	0.804711494697053
GO:0015459	potassium channel regulator activity	4/1163	59/18639	0.0677966101694915	1.08655289505516	0.506762669862758	0.804711494697053
GO:0070063	RNA polymerase binding	4/1163	59/18639	0.0677966101694915	1.08655289505516	0.506762669862758	0.804711494697053
GO:0070888	E-box binding	4/1163	59/18639	0.0677966101694915	1.08655289505516	0.506762669862758	0.804711494697053
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0003953	NAD+ nucleosidase activity	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0005114	type II transforming growth factor beta receptor binding	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0005536	D-glucose binding	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0008172	S-methyltransferase activity	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0008432	JUN kinase binding	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0010854	adenylate cyclase regulator activity	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0032050	clathrin heavy chain binding	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0032794	GTPase activating protein binding	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0035252	UDP-xylosyltransferase activity	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0042285	xylosyltransferase activity	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0043522	leucine zipper domain binding	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0045294	alpha-catenin binding	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0047676	arachidonate-CoA ligase activity	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0097493	structural molecule activity conferring elasticity	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0140031	phosphorylation-dependent protein binding	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0140537	transcription regulator activator activity	1/1163	11/18639	0.0909090909090909	1.45696865473306	0.507814983157114	0.804711494697053
GO:0004683	calcium/calmodulin-dependent protein kinase activity	2/1163	27/18639	0.0740740740740741	1.18715964459731	0.509026805947904	0.804711494697053
GO:0016405	CoA-ligase activity	2/1163	27/18639	0.0740740740740741	1.18715964459731	0.509026805947904	0.804711494697053
GO:0023026	MHC class II protein complex binding	2/1163	27/18639	0.0740740740740741	1.18715964459731	0.509026805947904	0.804711494697053
GO:0035255	ionotropic glutamate receptor binding	2/1163	27/18639	0.0740740740740741	1.18715964459731	0.509026805947904	0.804711494697053
GO:0036408	histone H3K14 acetyltransferase activity	2/1163	28/18639	0.0714285714285714	1.14476108586169	0.528730192882598	0.815832648763239
GO:0020037	heme binding	9/1163	142/18639	0.0633802816901408	1.01577392125755	0.529933262674295	0.815832648763239
GO:0016887	ATP hydrolysis activity	26/1163	417/18639	0.0623501199040767	0.999263873509962	0.531022923393103	0.815832648763239
GO:0019905	syntaxin binding	4/1163	61/18639	0.0655737704918033	1.05092820997139	0.533348005770734	0.815832648763239
GO:0004222	metalloendopeptidase activity	7/1163	110/18639	0.0636363636363636	1.01987805831314	0.534374538260435	0.815832648763239
GO:0016410	N-acyltransferase activity	6/1163	94/18639	0.0638297872340425	1.02297799162108	0.537367234232615	0.815832648763239
GO:0003995	acyl-CoA dehydrogenase activity	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0004000	adenosine deaminase activity	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0004032	aldose reductase (NADPH) activity	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0004859	phospholipase inhibitor activity	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0004875	complement receptor activity	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0005078	MAP-kinase scaffold activity	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0005095	GTPase inhibitor activity	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0005165	neurotrophin receptor binding	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0008179	adenylate cyclase binding	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0010853	cyclase activator activity	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0016208	AMP binding	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0016273	arginine N-methyltransferase activity	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0016274	protein-arginine N-methyltransferase activity	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0035197	siRNA binding	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0035497	cAMP response element binding	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0045295	gamma-catenin binding	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0097371	MDM2/MDM4 family protein binding	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0097677	STAT family protein binding	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:1990459	transferrin receptor binding	1/1163	12/18639	0.0833333333333333	1.33555460017197	0.538543519478152	0.815832648763239
GO:0140303	intramembrane lipid transporter activity	3/1163	45/18639	0.0666666666666667	1.06844368013758	0.538829005229674	0.815832648763239
GO:0005416	amino acid:monoatomic cation symporter activity	2/1163	29/18639	0.0689655172413793	1.10528656565956	0.547888665184505	0.82374869241027
GO:0010484	histone H3 acetyltransferase activity	2/1163	29/18639	0.0689655172413793	1.10528656565956	0.547888665184505	0.82374869241027
GO:0016417	S-acyltransferase activity	2/1163	29/18639	0.0689655172413793	1.10528656565956	0.547888665184505	0.82374869241027
GO:0043236	laminin binding	2/1163	29/18639	0.0689655172413793	1.10528656565956	0.547888665184505	0.82374869241027
GO:0099604	ligand-gated calcium channel activity	2/1163	29/18639	0.0689655172413793	1.10528656565956	0.547888665184505	0.82374869241027
GO:0005126	cytokine receptor binding	17/1163	275/18639	0.0618181818181818	0.990738685218479	0.551871005121085	0.823921572288767
GO:0008186	ATP-dependent activity, acting on RNA	5/1163	79/18639	0.0632911392405063	1.01434526595339	0.552692538463998	0.823921572288767
GO:0033293	monocarboxylic acid binding	5/1163	79/18639	0.0632911392405063	1.01434526595339	0.552692538463998	0.823921572288767
GO:0004180	carboxypeptidase activity	3/1163	46/18639	0.0652173913043478	1.04521664361285	0.553912351729247	0.823921572288767
GO:0016407	acetyltransferase activity	6/1163	96/18639	0.0625	1.00166595012898	0.558264094393392	0.823921572288767
GO:0001968	fibronectin binding	2/1163	30/18639	0.0666666666666667	1.06844368013758	0.566493465431461	0.823921572288767
GO:0043995	histone H4K5 acetyltransferase activity	2/1163	30/18639	0.0666666666666667	1.06844368013758	0.566493465431461	0.823921572288767
GO:0043996	histone H4K8 acetyltransferase activity	2/1163	30/18639	0.0666666666666667	1.06844368013758	0.566493465431461	0.823921572288767
GO:0043997	histone H4K12 acetyltransferase activity	2/1163	30/18639	0.0666666666666667	1.06844368013758	0.566493465431461	0.823921572288767
GO:0098918	structural constituent of synapse	2/1163	30/18639	0.0666666666666667	1.06844368013758	0.566493465431461	0.823921572288767
GO:0004535	poly(A)-specific ribonuclease activity	1/1163	13/18639	0.0769230769230769	1.23281963092797	0.567355130947895	0.823921572288767
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/1163	13/18639	0.0769230769230769	1.23281963092797	0.567355130947895	0.823921572288767
GO:0005542	folic acid binding	1/1163	13/18639	0.0769230769230769	1.23281963092797	0.567355130947895	0.823921572288767
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/1163	13/18639	0.0769230769230769	1.23281963092797	0.567355130947895	0.823921572288767
GO:0031432	titin binding	1/1163	13/18639	0.0769230769230769	1.23281963092797	0.567355130947895	0.823921572288767
GO:0035325	Toll-like receptor binding	1/1163	13/18639	0.0769230769230769	1.23281963092797	0.567355130947895	0.823921572288767
GO:0035673	oligopeptide transmembrane transporter activity	1/1163	13/18639	0.0769230769230769	1.23281963092797	0.567355130947895	0.823921572288767
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/1163	13/18639	0.0769230769230769	1.23281963092797	0.567355130947895	0.823921572288767
GO:0045159	myosin II binding	1/1163	13/18639	0.0769230769230769	1.23281963092797	0.567355130947895	0.823921572288767
GO:0061459	L-arginine transmembrane transporter activity	1/1163	13/18639	0.0769230769230769	1.23281963092797	0.567355130947895	0.823921572288767
GO:0071837	HMG box domain binding	1/1163	13/18639	0.0769230769230769	1.23281963092797	0.567355130947895	0.823921572288767
GO:0089720	caspase binding	1/1163	13/18639	0.0769230769230769	1.23281963092797	0.567355130947895	0.823921572288767
GO:0097157	pre-mRNA intronic binding	1/1163	13/18639	0.0769230769230769	1.23281963092797	0.567355130947895	0.823921572288767
GO:0140666	annealing activity	1/1163	13/18639	0.0769230769230769	1.23281963092797	0.567355130947895	0.823921572288767
GO:1901338	catecholamine binding	1/1163	13/18639	0.0769230769230769	1.23281963092797	0.567355130947895	0.823921572288767
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	8/1163	130/18639	0.0615384615384615	0.986255704742377	0.56795996290481	0.823921572288767
GO:0005504	fatty acid binding	3/1163	47/18639	0.0638297872340425	1.02297799162108	0.568697494547224	0.823921572288767
GO:0031072	heat shock protein binding	8/1163	131/18639	0.0610687022900763	0.978727035240527	0.576769633709641	0.834491731141136
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	3/1163	48/18639	0.0625	1.00166595012898	0.58317627472907	0.835224838610153
GO:0160215	deacylase activity	4/1163	65/18639	0.0615384615384615	0.986255704742377	0.584257729630201	0.835224838610153
GO:0008327	methyl-CpG binding	2/1163	31/18639	0.0645161290322581	1.03397775497185	0.584539047085993	0.835224838610153
GO:0016411	acylglycerol O-acyltransferase activity	2/1163	31/18639	0.0645161290322581	1.03397775497185	0.584539047085993	0.835224838610153
GO:0016878	acid-thiol ligase activity	2/1163	31/18639	0.0645161290322581	1.03397775497185	0.584539047085993	0.835224838610153
GO:0070325	lipoprotein particle receptor binding	2/1163	31/18639	0.0645161290322581	1.03397775497185	0.584539047085993	0.835224838610153
GO:0072349	modified amino acid transmembrane transporter activity	2/1163	31/18639	0.0645161290322581	1.03397775497185	0.584539047085993	0.835224838610153
GO:0004705	JUN kinase activity	1/1163	14/18639	0.0714285714285714	1.14476108586169	0.594369303755132	0.835224838610153
GO:0008474	palmitoyl-(protein) hydrolase activity	1/1163	14/18639	0.0714285714285714	1.14476108586169	0.594369303755132	0.835224838610153
GO:0008559	ABC-type xenobiotic transporter activity	1/1163	14/18639	0.0714285714285714	1.14476108586169	0.594369303755132	0.835224838610153
GO:0015926	glucosidase activity	1/1163	14/18639	0.0714285714285714	1.14476108586169	0.594369303755132	0.835224838610153
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/1163	14/18639	0.0714285714285714	1.14476108586169	0.594369303755132	0.835224838610153
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/1163	14/18639	0.0714285714285714	1.14476108586169	0.594369303755132	0.835224838610153
GO:0030983	mismatched DNA binding	1/1163	14/18639	0.0714285714285714	1.14476108586169	0.594369303755132	0.835224838610153
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/1163	14/18639	0.0714285714285714	1.14476108586169	0.594369303755132	0.835224838610153
GO:0042043	neurexin family protein binding	1/1163	14/18639	0.0714285714285714	1.14476108586169	0.594369303755132	0.835224838610153
GO:0042813	Wnt receptor activity	1/1163	14/18639	0.0714285714285714	1.14476108586169	0.594369303755132	0.835224838610153
GO:0043176	amine binding	1/1163	14/18639	0.0714285714285714	1.14476108586169	0.594369303755132	0.835224838610153
GO:0046030	inositol trisphosphate phosphatase activity	1/1163	14/18639	0.0714285714285714	1.14476108586169	0.594369303755132	0.835224838610153
GO:0061665	SUMO ligase activity	1/1163	14/18639	0.0714285714285714	1.14476108586169	0.594369303755132	0.835224838610153
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/1163	14/18639	0.0714285714285714	1.14476108586169	0.594369303755132	0.835224838610153
GO:0098599	palmitoyl hydrolase activity	1/1163	14/18639	0.0714285714285714	1.14476108586169	0.594369303755132	0.835224838610153
GO:0008235	metalloexopeptidase activity	4/1163	66/18639	0.0606060606060606	0.971312436488705	0.596471852611436	0.837085171745814
GO:0001222	transcription corepressor binding	3/1163	49/18639	0.0612244897959184	0.981223787881447	0.597341873362336	0.83721318626403
GO:0042910	xenobiotic transmembrane transporter activity	2/1163	32/18639	0.0625	1.00166595012898	0.602022708516427	0.837956526332195
GO:0000510	H3-H4 histone complex chaperone activity	9/1163	151/18639	0.0596026490066225	0.955231104758759	0.604938676751461	0.837956526332195
GO:0140584	chromatin extrusion motor activity	9/1163	151/18639	0.0596026490066225	0.955231104758759	0.604938676751461	0.837956526332195
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	9/1163	151/18639	0.0596026490066225	0.955231104758759	0.604938676751461	0.837956526332195
GO:0140849	ATP-dependent H2AZ histone chaperone activity	9/1163	151/18639	0.0596026490066225	0.955231104758759	0.604938676751461	0.837956526332195
GO:0032813	tumor necrosis factor receptor superfamily binding	3/1163	50/18639	0.06	0.961599312123818	0.611188728597608	0.837956526332195
GO:0015616	DNA translocase activity	9/1163	152/18639	0.0592105263157895	0.948946689595873	0.612904564465938	0.837956526332195
GO:0140674	ATP-dependent histone chaperone activity	9/1163	152/18639	0.0592105263157895	0.948946689595873	0.612904564465938	0.837956526332195
GO:0008238	exopeptidase activity	6/1163	102/18639	0.0588235294117647	0.942744423650802	0.618106273297615	0.837956526332195
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	2/1163	33/18639	0.0606060606060606	0.971312436488705	0.618944260124807	0.837956526332195
GO:0019239	deaminase activity	2/1163	33/18639	0.0606060606060606	0.971312436488705	0.618944260124807	0.837956526332195
GO:0016779	nucleotidyltransferase activity	8/1163	136/18639	0.0588235294117647	0.942744423650802	0.619509378064335	0.837956526332195
GO:0004089	carbonate dehydratase activity	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0004467	long-chain fatty acid-CoA ligase activity	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0005041	low-density lipoprotein particle receptor activity	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0008252	nucleotidase activity	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0015250	water channel activity	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0016846	carbon-sulfur lyase activity	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0030553	cGMP binding	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0031005	filamin binding	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0033130	acetylcholine receptor binding	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0042809	nuclear vitamin D receptor binding	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0045504	dynein heavy chain binding	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0047372	monoacylglycerol lipase activity	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0048531	beta-1,3-galactosyltransferase activity	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0050780	dopamine receptor binding	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0140776	protein-containing complex destabilizing activity	1/1163	15/18639	0.0666666666666667	1.06844368013758	0.619698082264275	0.837956526332195
GO:0008234	cysteine-type peptidase activity	11/1163	187/18639	0.0588235294117647	0.942744423650802	0.623924465063628	0.841561263949063
GO:0005048	signal sequence binding	3/1163	51/18639	0.0588235294117647	0.942744423650802	0.624712454540793	0.841561263949063
GO:0030544	Hsp70 protein binding	3/1163	51/18639	0.0588235294117647	0.942744423650802	0.624712454540793	0.841561263949063
GO:0008080	N-acetyltransferase activity	4/1163	69/18639	0.0579710144927536	0.929081460989196	0.63179545665504	0.850037691995205
GO:0015035	protein-disulfide reductase activity	2/1163	34/18639	0.0588235294117647	0.942744423650802	0.635305721880542	0.8526255750985
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/1163	34/18639	0.0588235294117647	0.942744423650802	0.635305721880542	0.8526255750985
GO:0003697	single-stranded DNA binding	7/1163	121/18639	0.0578512396694215	0.927161871193764	0.636098336026974	0.8526255750985
GO:0000062	fatty-acyl-CoA binding	1/1163	16/18639	0.0625	1.00166595012898	0.64344653213147	0.855012388184586
GO:0004707	MAP kinase activity	1/1163	16/18639	0.0625	1.00166595012898	0.64344653213147	0.855012388184586
GO:0008142	oxysterol binding	1/1163	16/18639	0.0625	1.00166595012898	0.64344653213147	0.855012388184586
GO:0016722	oxidoreductase activity, acting on metal ions	1/1163	16/18639	0.0625	1.00166595012898	0.64344653213147	0.855012388184586
GO:0022858	alanine transmembrane transporter activity	1/1163	16/18639	0.0625	1.00166595012898	0.64344653213147	0.855012388184586
GO:0055102	lipase inhibitor activity	1/1163	16/18639	0.0625	1.00166595012898	0.64344653213147	0.855012388184586
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/1163	16/18639	0.0625	1.00166595012898	0.64344653213147	0.855012388184586
GO:0034212	protein N-acetyltransferase activity	3/1163	53/18639	0.0566037735849057	0.90716916238096	0.650778383483025	0.860940193633316
GO:0010485	histone H4 acetyltransferase activity	2/1163	35/18639	0.0571428571428571	0.91580886868935	0.651111048766406	0.860940193633316
GO:0034061	DNA polymerase activity	2/1163	35/18639	0.0571428571428571	0.91580886868935	0.651111048766406	0.860940193633316
GO:0061631	ubiquitin conjugating enzyme activity	2/1163	35/18639	0.0571428571428571	0.91580886868935	0.651111048766406	0.860940193633316
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/1163	17/18639	0.0588235294117647	0.942744423650802	0.665713174623609	0.871463896561565
GO:0004659	prenyltransferase activity	1/1163	17/18639	0.0588235294117647	0.942744423650802	0.665713174623609	0.871463896561565
GO:0045236	CXCR chemokine receptor binding	1/1163	17/18639	0.0588235294117647	0.942744423650802	0.665713174623609	0.871463896561565
GO:0048038	quinone binding	1/1163	17/18639	0.0588235294117647	0.942744423650802	0.665713174623609	0.871463896561565
GO:0070492	oligosaccharide binding	1/1163	17/18639	0.0588235294117647	0.942744423650802	0.665713174623609	0.871463896561565
GO:1901567	fatty acid derivative binding	1/1163	17/18639	0.0588235294117647	0.942744423650802	0.665713174623609	0.871463896561565
GO:1990226	histone methyltransferase binding	1/1163	17/18639	0.0588235294117647	0.942744423650802	0.665713174623609	0.871463896561565
GO:0000993	RNA polymerase II complex binding	2/1163	36/18639	0.0555555555555556	0.890369733447979	0.666365881835913	0.871463896561565
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/1163	36/18639	0.0555555555555556	0.890369733447979	0.666365881835913	0.871463896561565
GO:0004843	cysteine-type deubiquitinase activity	6/1163	108/18639	0.0555555555555556	0.890369733447979	0.673082129936143	0.878674487937341
GO:0003689	DNA clamp loader activity	9/1163	160/18639	0.05625	0.901499355116079	0.67351421214918	0.878674487937341
GO:0004521	RNA endonuclease activity	4/1163	73/18639	0.0547945205479452	0.878172887784308	0.675686656550273	0.880440188838235
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	13/1163	229/18639	0.0567685589519651	0.909810120641167	0.677667383510182	0.881952103236616
GO:0043394	proteoglycan binding	2/1163	37/18639	0.0540540540540541	0.866305686598034	0.681077322759176	0.883331261951064
GO:0005372	water transmembrane transporter activity	1/1163	18/18639	0.0555555555555556	0.890369733447979	0.686590393929416	0.883331261951064
GO:0008308	voltage-gated monoatomic anion channel activity	1/1163	18/18639	0.0555555555555556	0.890369733447979	0.686590393929416	0.883331261951064
GO:0015280	ligand-gated sodium channel activity	1/1163	18/18639	0.0555555555555556	0.890369733447979	0.686590393929416	0.883331261951064
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/1163	18/18639	0.0555555555555556	0.890369733447979	0.686590393929416	0.883331261951064
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/1163	18/18639	0.0555555555555556	0.890369733447979	0.686590393929416	0.883331261951064
GO:0035615	clathrin adaptor activity	1/1163	18/18639	0.0555555555555556	0.890369733447979	0.686590393929416	0.883331261951064
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/1163	18/18639	0.0555555555555556	0.890369733447979	0.686590393929416	0.883331261951064
GO:1990381	ubiquitin-specific protease binding	1/1163	18/18639	0.0555555555555556	0.890369733447979	0.686590393929416	0.883331261951064
GO:0052689	carboxylic ester hydrolase activity	5/1163	92/18639	0.0543478260869565	0.871013869677371	0.687483495232837	0.883331261951064
GO:0019001	guanyl nucleotide binding	23/1163	400/18639	0.0575	0.921532674118659	0.688587532572085	0.883331261951064
GO:0032561	guanyl ribonucleotide binding	23/1163	400/18639	0.0575	0.921532674118659	0.688587532572085	0.883331261951064
GO:0042277	peptide binding	14/1163	249/18639	0.0562248995983936	0.9010970796341	0.694917811440827	0.888701259978174
GO:0005109	frizzled binding	2/1163	38/18639	0.0526315789473684	0.843508168529665	0.695253729899204	0.888701259978174
GO:0042887	amide transmembrane transporter activity	2/1163	38/18639	0.0526315789473684	0.843508168529665	0.695253729899204	0.888701259978174
GO:0019003	GDP binding	4/1163	75/18639	0.0533333333333333	0.85475494411006	0.696220865777479	0.888880559038943
GO:0140713	histone chaperone activity	9/1163	164/18639	0.0548780487804878	0.879511565966906	0.701583486119238	0.888907705592854
GO:0140097	catalytic activity, acting on DNA	19/1163	336/18639	0.056547619047619	0.906269192973836	0.704946500192156	0.888907705592854
GO:0051536	iron-sulfur cluster binding	4/1163	76/18639	0.0526315789473684	0.843508168529665	0.706132357175177	0.888907705592854
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/1163	19/18639	0.0526315789473684	0.843508168529665	0.706164819140741	0.888907705592854
GO:0005229	intracellularly calcium-gated chloride channel activity	1/1163	19/18639	0.0526315789473684	0.843508168529665	0.706164819140741	0.888907705592854
GO:0030506	ankyrin binding	1/1163	19/18639	0.0526315789473684	0.843508168529665	0.706164819140741	0.888907705592854
GO:0034987	immunoglobulin receptor binding	1/1163	19/18639	0.0526315789473684	0.843508168529665	0.706164819140741	0.888907705592854
GO:0043395	heparan sulfate proteoglycan binding	1/1163	19/18639	0.0526315789473684	0.843508168529665	0.706164819140741	0.888907705592854
GO:0097001	ceramide binding	1/1163	19/18639	0.0526315789473684	0.843508168529665	0.706164819140741	0.888907705592854
GO:0120227	acyl-CoA binding	1/1163	19/18639	0.0526315789473684	0.843508168529665	0.706164819140741	0.888907705592854
GO:0141147	intracellularly calcium-gated channel activity	1/1163	19/18639	0.0526315789473684	0.843508168529665	0.706164819140741	0.888907705592854
GO:1990380	K48-linked deubiquitinase activity	1/1163	19/18639	0.0526315789473684	0.843508168529665	0.706164819140741	0.888907705592854
GO:0016776	phosphotransferase activity, phosphate group as acceptor	2/1163	39/18639	0.0512820512820513	0.821879753951981	0.708904534113216	0.891312718329482
GO:0003724	RNA helicase activity	4/1163	77/18639	0.051948051948052	0.832553516990318	0.71580690443534	0.892160949214003
GO:0051540	metal cluster binding	4/1163	77/18639	0.051948051948052	0.832553516990318	0.71580690443534	0.892160949214003
GO:0005262	calcium channel activity	7/1163	131/18639	0.0534351145038168	0.856386155835461	0.716479161066109	0.892160949214003
GO:0031593	polyubiquitin modification-dependent protein binding	3/1163	59/18639	0.0508474576271186	0.814914671291371	0.721071185086914	0.892160949214003
GO:0015036	disulfide oxidoreductase activity	2/1163	40/18639	0.05	0.801332760103181	0.722040072614686	0.892160949214003
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	2/1163	40/18639	0.05	0.801332760103181	0.722040072614686	0.892160949214003
GO:0071949	FAD binding	2/1163	40/18639	0.05	0.801332760103181	0.722040072614686	0.892160949214003
GO:0000339	RNA cap binding	1/1163	20/18639	0.05	0.801332760103181	0.724517682477977	0.892160949214003
GO:0001614	purinergic nucleotide receptor activity	1/1163	20/18639	0.05	0.801332760103181	0.724517682477977	0.892160949214003
GO:0001972	retinoic acid binding	1/1163	20/18639	0.05	0.801332760103181	0.724517682477977	0.892160949214003
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/1163	20/18639	0.05	0.801332760103181	0.724517682477977	0.892160949214003
GO:0010851	cyclase regulator activity	1/1163	20/18639	0.05	0.801332760103181	0.724517682477977	0.892160949214003
GO:0016004	phospholipase activator activity	1/1163	20/18639	0.05	0.801332760103181	0.724517682477977	0.892160949214003
GO:0016408	C-acyltransferase activity	1/1163	20/18639	0.05	0.801332760103181	0.724517682477977	0.892160949214003
GO:0016502	nucleotide receptor activity	1/1163	20/18639	0.05	0.801332760103181	0.724517682477977	0.892160949214003
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/1163	20/18639	0.05	0.801332760103181	0.724517682477977	0.892160949214003
GO:0043024	ribosomal small subunit binding	1/1163	20/18639	0.05	0.801332760103181	0.724517682477977	0.892160949214003
GO:0052745	inositol phosphate phosphatase activity	1/1163	20/18639	0.05	0.801332760103181	0.724517682477977	0.892160949214003
GO:0101005	deubiquitinase activity	6/1163	115/18639	0.0521739130434783	0.836173314890276	0.730459340520466	0.895432876773994
GO:0001098	basal transcription machinery binding	3/1163	60/18639	0.05	0.801332760103181	0.731646377243746	0.895432876773994
GO:0001099	basal RNA polymerase II transcription machinery binding	3/1163	60/18639	0.05	0.801332760103181	0.731646377243746	0.895432876773994
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	3/1163	60/18639	0.05	0.801332760103181	0.731646377243746	0.895432876773994
GO:0001530	lipopolysaccharide binding	2/1163	41/18639	0.0487804878048781	0.78178805863725	0.734671439362477	0.895432876773994
GO:0016877	ligase activity, forming carbon-sulfur bonds	2/1163	41/18639	0.0487804878048781	0.78178805863725	0.734671439362477	0.895432876773994
GO:0042287	MHC protein binding	2/1163	41/18639	0.0487804878048781	0.78178805863725	0.734671439362477	0.895432876773994
GO:0061650	ubiquitin-like protein conjugating enzyme activity	2/1163	41/18639	0.0487804878048781	0.78178805863725	0.734671439362477	0.895432876773994
GO:0140318	protein transporter activity	2/1163	41/18639	0.0487804878048781	0.78178805863725	0.734671439362477	0.895432876773994
GO:0051087	protein-folding chaperone binding	7/1163	134/18639	0.0522388059701493	0.837213331451085	0.738092039865371	0.896911745645103
GO:0042626	ATPase-coupled transmembrane transporter activity	5/1163	98/18639	0.0510204081632653	0.817686489901206	0.739489020486886	0.896911745645103
GO:0005525	GTP binding	21/1163	378/18639	0.0555555555555556	0.890369733447979	0.740814150403415	0.896911745645103
GO:0005248	voltage-gated sodium channel activity	1/1163	21/18639	0.0476190476190476	0.763174057241125	0.741725155235811	0.896911745645103
GO:0009975	cyclase activity	1/1163	21/18639	0.0476190476190476	0.763174057241125	0.741725155235811	0.896911745645103
GO:0015125	bile acid transmembrane transporter activity	1/1163	21/18639	0.0476190476190476	0.763174057241125	0.741725155235811	0.896911745645103
GO:0036122	BMP binding	1/1163	21/18639	0.0476190476190476	0.763174057241125	0.741725155235811	0.896911745645103
GO:0048306	calcium-dependent protein binding	4/1163	80/18639	0.05	0.801332760103181	0.743416611899532	0.897947031226963
GO:0004402	histone acetyltransferase activity	2/1163	42/18639	0.0476190476190476	0.763174057241125	0.746810350564261	0.899015819548242
GO:0043175	RNA polymerase core enzyme binding	2/1163	42/18639	0.0476190476190476	0.763174057241125	0.746810350564261	0.899015819548242
GO:0051879	Hsp90 protein binding	2/1163	42/18639	0.0476190476190476	0.763174057241125	0.746810350564261	0.899015819548242
GO:0005539	glycosaminoglycan binding	13/1163	242/18639	0.0537190082644628	0.860936023251352	0.750344080411076	0.902259380807501
GO:0015101	organic cation transmembrane transporter activity	4/1163	81/18639	0.0493827160493827	0.79143976306487	0.752152836948887	0.903371528627434
GO:0008201	heparin binding	9/1163	172/18639	0.0523255813953488	0.838604051270771	0.752949664790866	0.903371528627434
GO:0008649	rRNA methyltransferase activity	1/1163	22/18639	0.0454545454545455	0.728484327366529	0.757858662833874	0.90421538573409
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/1163	22/18639	0.0454545454545455	0.728484327366529	0.757858662833874	0.90421538573409
GO:0031683	G-protein beta/gamma-subunit complex binding	1/1163	22/18639	0.0454545454545455	0.728484327366529	0.757858662833874	0.90421538573409
GO:0034062	5'-3' RNA polymerase activity	1/1163	22/18639	0.0454545454545455	0.728484327366529	0.757858662833874	0.90421538573409
GO:0097747	RNA polymerase activity	1/1163	22/18639	0.0454545454545455	0.728484327366529	0.757858662833874	0.90421538573409
GO:1901682	sulfur compound transmembrane transporter activity	3/1163	63/18639	0.0476190476190476	0.763174057241125	0.761477801813658	0.907526205043994
GO:0001664	G protein-coupled receptor binding	16/1163	297/18639	0.0538720538720539	0.863388832434404	0.763405352235083	0.908815895517956
GO:0008135	translation factor activity, RNA binding	4/1163	83/18639	0.0481927710843374	0.772368925400657	0.76893572606808	0.911139329814874
GO:0019205	nucleobase-containing compound kinase activity	2/1163	44/18639	0.0454545454545455	0.728484327366529	0.769660070919432	0.911139329814874
GO:0030020	extracellular matrix structural constituent conferring tensile strength	2/1163	44/18639	0.0454545454545455	0.728484327366529	0.769660070919432	0.911139329814874
GO:0015171	amino acid transmembrane transporter activity	5/1163	102/18639	0.0490196078431373	0.785620353042335	0.77045943225092	0.911139329814874
GO:0004602	glutathione peroxidase activity	1/1163	23/18639	0.0434782608695652	0.696811095741897	0.772985180270852	0.911139329814874
GO:0005212	structural constituent of eye lens	1/1163	23/18639	0.0434782608695652	0.696811095741897	0.772985180270852	0.911139329814874
GO:0016849	phosphorus-oxygen lyase activity	1/1163	23/18639	0.0434782608695652	0.696811095741897	0.772985180270852	0.911139329814874
GO:0099186	structural constituent of postsynapse	1/1163	23/18639	0.0434782608695652	0.696811095741897	0.772985180270852	0.911139329814874
GO:0140102	catalytic activity, acting on a rRNA	1/1163	23/18639	0.0434782608695652	0.696811095741897	0.772985180270852	0.911139329814874
GO:0180051	translation factor activity	4/1163	84/18639	0.0476190476190476	0.763174057241125	0.776986984591206	0.914853240345615
GO:0140104	molecular carrier activity	13/1163	249/18639	0.0522088353413655	0.836733002517378	0.784605713333772	0.918789437991312
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/1163	24/18639	0.0416666666666667	0.667777300085985	0.787167509199999	0.918789437991312
GO:0004622	lysophospholipase activity	1/1163	24/18639	0.0416666666666667	0.667777300085985	0.787167509199999	0.918789437991312
GO:0005315	phosphate transmembrane transporter activity	1/1163	24/18639	0.0416666666666667	0.667777300085985	0.787167509199999	0.918789437991312
GO:0005540	hyaluronic acid binding	1/1163	24/18639	0.0416666666666667	0.667777300085985	0.787167509199999	0.918789437991312
GO:0015295	solute:proton symporter activity	1/1163	24/18639	0.0416666666666667	0.667777300085985	0.787167509199999	0.918789437991312
GO:0060229	lipase activator activity	1/1163	24/18639	0.0416666666666667	0.667777300085985	0.787167509199999	0.918789437991312
GO:0070840	dynein complex binding	1/1163	24/18639	0.0416666666666667	0.667777300085985	0.787167509199999	0.918789437991312
GO:0000030	mannosyltransferase activity	1/1163	25/18639	0.04	0.641066208082545	0.800464537768379	0.926371718205768
GO:0005251	delayed rectifier potassium channel activity	1/1163	25/18639	0.04	0.641066208082545	0.800464537768379	0.926371718205768
GO:0008483	transaminase activity	1/1163	25/18639	0.04	0.641066208082545	0.800464537768379	0.926371718205768
GO:0015271	outward rectifier potassium channel activity	1/1163	25/18639	0.04	0.641066208082545	0.800464537768379	0.926371718205768
GO:0015645	fatty acid ligase activity	1/1163	25/18639	0.04	0.641066208082545	0.800464537768379	0.926371718205768
GO:0120515	fatty acid-CoA ligase activity	1/1163	25/18639	0.04	0.641066208082545	0.800464537768379	0.926371718205768
GO:0043495	protein-membrane adaptor activity	2/1163	47/18639	0.0425531914893617	0.681985327747389	0.800557512756426	0.926371718205768
GO:0061733	protein-lysine-acetyltransferase activity	2/1163	47/18639	0.0425531914893617	0.681985327747389	0.800557512756426	0.926371718205768
GO:0016829	lyase activity	10/1163	200/18639	0.05	0.801332760103181	0.807000045482597	0.932822633219131
GO:0001637	G protein-coupled chemoattractant receptor activity	1/1163	26/18639	0.0384615384615385	0.616409815463986	0.812931484291178	0.936657390796373
GO:0004950	chemokine receptor activity	1/1163	26/18639	0.0384615384615385	0.616409815463986	0.812931484291178	0.936657390796373
GO:0070006	metalloaminopeptidase activity	1/1163	26/18639	0.0384615384615385	0.616409815463986	0.812931484291178	0.936657390796373
GO:0061135	endopeptidase regulator activity	9/1163	184/18639	0.0489130434782609	0.783912482709634	0.817880599292027	0.940771279998783
GO:0015085	calcium ion transmembrane transporter activity	7/1163	147/18639	0.0476190476190476	0.763174057241125	0.818252229580337	0.940771279998783
GO:0005104	fibroblast growth factor receptor binding	1/1163	27/18639	0.037037037037037	0.593579822298653	0.824620125765919	0.944053924598896
GO:0008320	protein transmembrane transporter activity	1/1163	27/18639	0.037037037037037	0.593579822298653	0.824620125765919	0.944053924598896
GO:0008395	steroid hydroxylase activity	1/1163	27/18639	0.037037037037037	0.593579822298653	0.824620125765919	0.944053924598896
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/1163	27/18639	0.037037037037037	0.593579822298653	0.824620125765919	0.944053924598896
GO:0140299	molecular sensor activity	3/1163	71/18639	0.0422535211267606	0.677182614171703	0.827994533057435	0.946908641528449
GO:0005201	extracellular matrix structural constituent	8/1163	168/18639	0.0476190476190476	0.763174057241125	0.829962348075952	0.94815039764256
GO:0043022	ribosome binding	5/1163	112/18639	0.0446428571428571	0.715475678663555	0.835500521256873	0.948422382634251
GO:0005242	inward rectifier potassium channel activity	1/1163	28/18639	0.0357142857142857	0.572380542930844	0.835579012169005	0.948422382634251
GO:0016866	intramolecular transferase activity	1/1163	28/18639	0.0357142857142857	0.572380542930844	0.835579012169005	0.948422382634251
GO:0046625	sphingolipid binding	1/1163	28/18639	0.0357142857142857	0.572380542930844	0.835579012169005	0.948422382634251
GO:0005272	sodium channel activity	2/1163	51/18639	0.0392156862745098	0.628496282433868	0.836005785107845	0.948422382634251
GO:0046943	carboxylic acid transmembrane transporter activity	9/1163	188/18639	0.0478723404255319	0.767233493715812	0.836376203476531	0.948422382634251
GO:0140597	protein carrier chaperone	9/1163	188/18639	0.0478723404255319	0.767233493715812	0.836376203476531	0.948422382634251
GO:0005179	hormone activity	6/1163	132/18639	0.0454545454545455	0.728484327366529	0.83905300395384	0.950455194152137
GO:0005342	organic acid transmembrane transporter activity	9/1163	189/18639	0.0476190476190476	0.763174057241125	0.84076400706856	0.950639348838426
GO:0061134	peptidase regulator activity	11/1163	226/18639	0.0486725663716814	0.780058439038495	0.840984205344506	0.950639348838426
GO:0035250	UDP-galactosyltransferase activity	1/1163	29/18639	0.0344827586206897	0.55264328282978	0.845853667418452	0.954137137958904
GO:0106222	lncRNA binding	1/1163	29/18639	0.0344827586206897	0.55264328282978	0.845853667418452	0.954137137958904
GO:0140296	general transcription initiation factor binding	2/1163	53/18639	0.0377358490566038	0.604779441587307	0.851504184550669	0.95950419118655
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/1163	30/18639	0.0333333333333333	0.534221840068788	0.855486777831796	0.960969995997054
GO:0016769	transferase activity, transferring nitrogenous groups	1/1163	30/18639	0.0333333333333333	0.534221840068788	0.855486777831796	0.960969995997054
GO:0048019	receptor antagonist activity	1/1163	30/18639	0.0333333333333333	0.534221840068788	0.855486777831796	0.960969995997054
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	2/1163	54/18639	0.037037037037037	0.593579822298653	0.858742153335287	0.962615031110984
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	2/1163	54/18639	0.037037037037037	0.593579822298653	0.858742153335287	0.962615031110984
GO:0017022	myosin binding	3/1163	76/18639	0.0394736842105263	0.632631126397248	0.86095013371864	0.964084785153686
GO:0005164	tumor necrosis factor receptor binding	1/1163	31/18639	0.032258064516129	0.516988877485923	0.864518368856656	0.965064638131781
GO:0017147	Wnt-protein binding	1/1163	31/18639	0.032258064516129	0.516988877485923	0.864518368856656	0.965064638131781
GO:0047499	calcium-independent phospholipase A2 activity	1/1163	31/18639	0.032258064516129	0.516988877485923	0.864518368856656	0.965064638131781
GO:0008374	O-acyltransferase activity	2/1163	55/18639	0.0363636363636364	0.582787461893223	0.865656002379273	0.965332160329584
GO:0030170	pyridoxal phosphate binding	2/1163	56/18639	0.0357142857142857	0.572380542930844	0.872257957420384	0.968482888145871
GO:0008378	galactosyltransferase activity	1/1163	32/18639	0.03125	0.500832975064488	0.872985970803115	0.968482888145871
GO:0022884	macromolecule transmembrane transporter activity	1/1163	32/18639	0.03125	0.500832975064488	0.872985970803115	0.968482888145871
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/1163	32/18639	0.03125	0.500832975064488	0.872985970803115	0.968482888145871
GO:0047498	calcium-dependent phospholipase A2 activity	1/1163	32/18639	0.03125	0.500832975064488	0.872985970803115	0.968482888145871
GO:0015370	solute:sodium symporter activity	3/1163	79/18639	0.0379746835443038	0.608607159572036	0.877947228852183	0.972659094223344
GO:0070279	vitamin B6 binding	2/1163	57/18639	0.0350877192982456	0.562338779019776	0.878559981851969	0.972659094223344
GO:0004540	RNA nuclease activity	5/1163	121/18639	0.0413223140495868	0.662258479424117	0.880360256026732	0.973649460111869
GO:1901681	sulfur compound binding	13/1163	275/18639	0.0472727272727273	0.75762370046119	0.882473983896134	0.974984103482368
GO:0003924	GTPase activity	16/1163	331/18639	0.0483383685800604	0.774702366262894	0.884512740813635	0.975299275884606
GO:0008408	3'-5' exonuclease activity	2/1163	58/18639	0.0344827586206897	0.55264328282978	0.884573761848828	0.975299275884606
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	1/1163	34/18639	0.0294117647058824	0.471372211825401	0.888367775849123	0.978478851473164
GO:0036002	pre-mRNA binding	2/1163	59/18639	0.0338983050847458	0.543276447527581	0.89031069436679	0.979615144774104
GO:0000175	3'-5'-RNA exonuclease activity	1/1163	35/18639	0.0285714285714286	0.457904434344675	0.895345914880968	0.982139651527592
GO:0004623	phospholipase A2 activity	1/1163	35/18639	0.0285714285714286	0.457904434344675	0.895345914880968	0.982139651527592
GO:0016229	steroid dehydrogenase activity	1/1163	35/18639	0.0285714285714286	0.457904434344675	0.895345914880968	0.982139651527592
GO:0030246	carbohydrate binding	13/1163	280/18639	0.0464285714285714	0.744094705810097	0.896419404457458	0.982314841785696
GO:0016836	hydro-lyase activity	2/1163	61/18639	0.0327868852459016	0.525464104985693	0.900998104432964	0.985294529120786
GO:0004033	aldo-keto reductase (NADPH) activity	1/1163	36/18639	0.0277777777777778	0.44518486672399	0.901888201539398	0.985294529120786
GO:0005484	SNAP receptor activity	1/1163	36/18639	0.0277777777777778	0.44518486672399	0.901888201539398	0.985294529120786
GO:0004519	endonuclease activity	5/1163	127/18639	0.0393700787401575	0.6309706772466	0.904091231660972	0.98669855232035
GO:0015179	L-amino acid transmembrane transporter activity	2/1163	62/18639	0.032258064516129	0.516988877485923	0.905969856204449	0.987746039979495
GO:0030280	structural constituent of skin epidermis	1/1163	37/18639	0.027027027027027	0.433152843299017	0.908021837061071	0.988980217670366
GO:0050660	flavin adenine dinucleotide binding	3/1163	86/18639	0.0348837209302326	0.559069367513848	0.910617661392089	0.989899239794244
GO:0005507	copper ion binding	2/1163	63/18639	0.0317460317460317	0.508782704827417	0.910707300610704	0.989899239794244
GO:0005501	retinoid binding	1/1163	38/18639	0.0263157894736842	0.421754084264832	0.913772326443824	0.990227067466846
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/1163	38/18639	0.0263157894736842	0.421754084264832	0.913772326443824	0.990227067466846
GO:0019840	isoprenoid binding	1/1163	38/18639	0.0263157894736842	0.421754084264832	0.913772326443824	0.990227067466846
GO:0008514	organic anion transmembrane transporter activity	12/1163	269/18639	0.0446096654275093	0.71494372648611	0.915929798192408	0.99156549149732
GO:0004532	RNA exonuclease activity	1/1163	40/18639	0.025	0.400666380051591	0.924218033150121	0.996523957508907
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/1163	40/18639	0.025	0.400666380051591	0.924218033150121	0.996523957508907
GO:0061791	GTPase motor activity	1/1163	40/18639	0.025	0.400666380051591	0.924218033150121	0.996523957508907
GO:1990606	membrane scission GTPase motor activity	1/1163	40/18639	0.025	0.400666380051591	0.924218033150121	0.996523957508907
GO:0008227	G protein-coupled amine receptor activity	1/1163	41/18639	0.024390243902439	0.390894029318625	0.928956697994812	0.999087777574952
GO:0015175	neutral L-amino acid transmembrane transporter activity	1/1163	41/18639	0.024390243902439	0.390894029318625	0.928956697994812	0.999087777574952
GO:0140375	immune receptor activity	6/1163	156/18639	0.0384615384615385	0.616409815463986	0.92938397913949	0.999087777574952
GO:0099094	ligand-gated monoatomic cation channel activity	5/1163	136/18639	0.0367647058823529	0.589215264781751	0.931982501816046	0.999999999487495
GO:0004520	DNA endonuclease activity	1/1163	42/18639	0.0238095238095238	0.381587028620563	0.933399291834581	0.999999999487495
GO:0042056	chemoattractant activity	1/1163	42/18639	0.0238095238095238	0.381587028620563	0.933399291834581	0.999999999487495
GO:0015294	solute:monoatomic cation symporter activity	4/1163	116/18639	0.0344827586206897	0.55264328282978	0.936425923518654	0.999999999487495
GO:0005245	voltage-gated calcium channel activity	1/1163	43/18639	0.0232558139534884	0.372712911675898	0.93756429821176	0.999999999487495
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/1163	43/18639	0.0232558139534884	0.372712911675898	0.93756429821176	0.999999999487495
GO:0003730	mRNA 3'-UTR binding	11/1163	262/18639	0.0419847328244275	0.672874836727862	0.940927656053812	0.999999999487495
GO:0016790	thiolester hydrolase activity	1/1163	44/18639	0.0227272727272727	0.364242163683264	0.941469047683674	0.999999999487495
GO:0030547	signaling receptor inhibitor activity	1/1163	44/18639	0.0227272727272727	0.364242163683264	0.941469047683674	0.999999999487495
GO:0008083	growth factor activity	6/1163	162/18639	0.037037037037037	0.593579822298653	0.943378617025861	0.999999999487495
GO:0004896	cytokine receptor activity	3/1163	96/18639	0.03125	0.500832975064488	0.943617739661056	0.999999999487495
GO:0042379	chemokine receptor binding	2/1163	72/18639	0.0277777777777778	0.44518486672399	0.944322698756176	0.999999999487495
GO:0015081	sodium ion transmembrane transporter activity	6/1163	164/18639	0.0365853658536585	0.586341043977938	0.947460167989263	0.999999999487495
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/1163	46/18639	0.0217391304347826	0.348405547870948	0.948561759923988	0.999999999487495
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/1163	46/18639	0.0217391304347826	0.348405547870948	0.948561759923988	0.999999999487495
GO:0015108	chloride transmembrane transporter activity	4/1163	121/18639	0.0330578512396694	0.529806783539293	0.948649880394124	0.999999999487495
GO:0003684	damaged DNA binding	2/1163	74/18639	0.027027027027027	0.433152843299017	0.9499496160077	0.999999999487495
GO:0008528	G protein-coupled peptide receptor activity	4/1163	122/18639	0.0327868852459016	0.525464104985693	0.950819898369111	0.999999999487495
GO:0099095	ligand-gated monoatomic anion channel activity	1/1163	47/18639	0.0212765957446809	0.340992663873694	0.951779243558066	0.999999999487495
GO:0004175	endopeptidase activity	18/1163	405/18639	0.0444444444444444	0.712295786758383	0.952562598182855	0.999999999487495
GO:0016763	pentosyltransferase activity	1/1163	49/18639	0.0204081632653061	0.327074595960482	0.957623490799648	0.999999999487495
GO:0008509	monoatomic anion transmembrane transporter activity	5/1163	149/18639	0.0335570469798658	0.537807221545759	0.959530296756537	0.999999999487495
GO:0005253	monoatomic anion channel activity	3/1163	103/18639	0.029126213592233	0.466795782584378	0.95955110753811	0.999999999487495
GO:0048020	CCR chemokine receptor binding	1/1163	50/18639	0.02	0.320533104041273	0.960274587098734	0.999999999487495
GO:0016835	carbon-oxygen lyase activity	2/1163	79/18639	0.0253164556962025	0.405738106381358	0.96173823696122	0.999999999487495
GO:0001653	peptide receptor activity	4/1163	128/18639	0.03125	0.500832975064488	0.9621627398608	0.999999999487495
GO:0003743	translation initiation factor activity	1/1163	51/18639	0.0196078431372549	0.314248141216934	0.962759963138552	0.999999999487495
GO:0004497	monooxygenase activity	3/1163	106/18639	0.0283018867924528	0.45358458119048	0.964993198035485	0.999999999487495
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	1/1163	52/18639	0.0192307692307692	0.308204907731993	0.965089969748723	0.999999999487495
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/1163	53/18639	0.0188679245283019	0.302389720793653	0.967274311771762	0.999999999487495
GO:0043021	ribonucleoprotein complex binding	6/1163	177/18639	0.0338983050847458	0.543276447527581	0.968129771735803	0.999999999487495
GO:0005254	chloride channel activity	2/1163	83/18639	0.0240963855421687	0.386184462700328	0.969201354584467	0.999999999487495
GO:0004527	exonuclease activity	2/1163	84/18639	0.0238095238095238	0.381587028620563	0.970835534144537	0.999999999487495
GO:0004866	endopeptidase inhibitor activity	5/1163	161/18639	0.031055900621118	0.497722211244212	0.975464877770122	0.999999999487495
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	1/1163	58/18639	0.0172413793103448	0.27632164141489	0.976310373824947	0.999999999487495
GO:0015276	ligand-gated monoatomic ion channel activity	6/1163	186/18639	0.032258064516129	0.516988877485923	0.977740943788745	0.999999999487495
GO:0004518	nuclease activity	7/1163	209/18639	0.0334928229665072	0.536777925427968	0.978461145305651	0.999999999487495
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/1163	60/18639	0.0166666666666667	0.267110920034394	0.979183148091989	0.999999999487495
GO:0015103	inorganic anion transmembrane transporter activity	5/1163	165/18639	0.0303030303030303	0.485656218244352	0.9793190944173	0.999999999487495
GO:0022834	ligand-gated channel activity	6/1163	188/18639	0.0319148936170213	0.511488995810541	0.979474647614098	0.999999999487495
GO:0015399	primary active transmembrane transporter activity	5/1163	166/18639	0.0301204819277108	0.48273057837541	0.980190009445121	0.999999999487495
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	1/1163	61/18639	0.0163934426229508	0.262732052492846	0.980486232152972	0.999999999487495
GO:0030414	peptidase inhibitor activity	5/1163	169/18639	0.029585798816568	0.474161396510758	0.982601047835209	0.999999999487495
GO:0015293	symporter activity	4/1163	146/18639	0.0273972602739726	0.439086443892154	0.983261948640136	0.999999999487495
GO:0004536	DNA nuclease activity	1/1163	64/18639	0.015625	0.250416487532244	0.983926516422375	0.999999999487495
GO:0019843	rRNA binding	1/1163	65/18639	0.0153846153846154	0.246563926185594	0.984932893886751	0.999999999487495
GO:0005267	potassium channel activity	3/1163	124/18639	0.0241935483870968	0.387741658114443	0.985633667876286	0.999999999487495
GO:0005249	voltage-gated potassium channel activity	2/1163	98/18639	0.0204081632653061	0.327074595960482	0.986543798924093	0.999999999487495
GO:0008173	RNA methyltransferase activity	1/1163	67/18639	0.0149253731343284	0.239203808986024	0.986760705783742	0.999999999487495
GO:0140223	general transcription initiation factor activity	1/1163	68/18639	0.0147058823529412	0.2356861059127	0.98758976561432	0.999999999487495
GO:0022836	gated channel activity	11/1163	318/18639	0.0345911949685535	0.554381154788364	0.990563674307413	0.999999999487495
GO:0005261	monoatomic cation channel activity	12/1163	341/18639	0.0351906158357771	0.56398786634828	0.991104421157334	0.999999999487495
GO:0015079	potassium ion transmembrane transporter activity	4/1163	160/18639	0.025	0.400666380051591	0.991351616874631	0.999999999487495
GO:0005216	monoatomic ion channel activity	17/1163	448/18639	0.0379464285714286	0.608154326864022	0.991962998321869	0.999999999487495
GO:0044183	protein folding chaperone	1/1163	75/18639	0.0133333333333333	0.213688736027515	0.992108813953517	0.999999999487495
GO:0008236	serine-type peptidase activity	5/1163	194/18639	0.0257731958762887	0.413058123764526	0.994317071049803	0.999999999487495
GO:0022843	voltage-gated monoatomic cation channel activity	3/1163	143/18639	0.020979020979021	0.336223535707629	0.994590894159859	0.999999999487495
GO:0009055	electron transfer activity	2/1163	116/18639	0.0172413793103448	0.27632164141489	0.995137008406847	0.999999999487495
GO:0017171	serine hydrolase activity	5/1163	198/18639	0.0252525252525253	0.404713515203627	0.995275303152235	0.999999999487495
GO:0005244	voltage-gated monoatomic ion channel activity	4/1163	173/18639	0.023121387283237	0.370558501781818	0.995395675196147	0.999999999487495
GO:0022853	active monoatomic ion transmembrane transporter activity	2/1163	118/18639	0.0169491525423729	0.27163822376379	0.9956628234637	0.999999999487495
GO:0022832	voltage-gated channel activity	4/1163	175/18639	0.0228571428571429	0.36632354747574	0.995826800241158	0.999999999487495
GO:0046873	metal ion transmembrane transporter activity	16/1163	450/18639	0.0355555555555556	0.569836629406707	0.996129641562991	0.999999999487495
GO:0016651	oxidoreductase activity, acting on NAD(P)H	1/1163	88/18639	0.0113636363636364	0.182121081841632	0.996597840409899	0.999999999487495
GO:0004867	serine-type endopeptidase inhibitor activity	1/1163	95/18639	0.0105263157894737	0.168701633705933	0.997837789689406	0.999999999487495
GO:0004252	serine-type endopeptidase activity	3/1163	176/18639	0.0170454545454545	0.273181622762448	0.999073004559634	0.999999999487495
GO:0016853	isomerase activity	3/1163	180/18639	0.0166666666666667	0.267110920034394	0.999254971372604	0.999999999487495
GO:0015291	secondary active transmembrane transporter activity	5/1163	287/18639	0.0174216027874564	0.279210020941875	0.999942271844348	0.999999999487495
GO:0005125	cytokine activity	3/1163	234/18639	0.0128205128205128	0.205469938487995	0.999963846317775	0.999999999487495
GO:0003823	antigen binding	1/1163	174/18639	0.00574712643678161	0.0921072138049634	0.99998717989368	0.999999999487495
GO:0003735	structural constituent of ribosome	1/1163	175/18639	0.00571428571428571	0.091580886868935	0.999987987355562	0.999999999487495
GO:0022804	active transmembrane transporter activity	10/1163	457/18639	0.0218818380743982	0.350692674005769	0.99998915460767	0.999999999487495
GO:0015078	proton transmembrane transporter activity	1/1163	185/18639	0.00540540540540541	0.0866305686598034	0.999993733549793	0.999999999487495
GO:0045182	translation regulator activity	5/1163	356/18639	0.0140449438202247	0.225093471939096	0.999998557143617	0.999999999487495
GO:0030371	translation repressor activity	1/1163	329/18639	0.00303951367781155	0.048713237696242	0.999999999487495	0.999999999487495