ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0042605	peptide antigen binding	19/715	45/18639	0.422222222222222	11.0067132867133	9.37694810825689e-16	8.504891934189e-13
GO:0023026	MHC class II protein complex binding	12/715	27/18639	0.444444444444444	11.586013986014	9.4899526441038e-11	4.30369352410107e-08
GO:0051082	unfolded protein binding	23/715	121/18639	0.190082644628099	4.95517540310929	1.8149789689814e-10	5.48728641622044e-08
GO:0023023	MHC protein complex binding	13/715	37/18639	0.351351351351351	9.15921375921376	5.31742890970748e-10	1.20572700527617e-07
GO:0044183	protein folding chaperone	16/715	75/18639	0.213333333333333	5.56128671328671	1.92433005922157e-08	3.49073472742793e-06
GO:0140662	ATP-dependent protein folding chaperone	11/715	40/18639	0.275	7.16884615384615	2.04962445695452e-07	3.09834897076291e-05
GO:0140416	transcription regulator inhibitor activity	10/715	33/18639	0.303030303030303	7.89955499046408	2.69257084418486e-07	3.4888025081081e-05
GO:0031072	heat shock protein binding	19/715	131/18639	0.145038167938931	3.78093204505418	6.12553958836913e-07	6.75260599249619e-05
GO:0031625	ubiquitin protein ligase binding	31/715	302/18639	0.102649006622517	2.67590885935257	6.70049106201386e-07	6.75260599249619e-05
GO:0044389	ubiquitin-like protein ligase binding	32/715	322/18639	0.0993788819875776	2.59066151240064	9.09236556603925e-07	8.2467755683976e-05
GO:0042277	peptide binding	27/715	249/18639	0.108433734939759	2.82670823152751	1.21762176593435e-06	0.000100398449245678
GO:0003823	antigen binding	20/715	174/18639	0.114942528735632	2.99638292741741	1.21852767753513e-05	0.000921003836270303
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	5/715	10/18639	0.5	13.0342657342657	1.75802392509866e-05	0.00122655976928037
GO:0035198	miRNA binding	9/715	42/18639	0.214285714285714	5.58611388611389	2.44567628973777e-05	0.00158444885342297
GO:0051087	protein-folding chaperone binding	16/715	134/18639	0.119402985074627	3.1126604738545	5.59030087753272e-05	0.00338026859728145
GO:0061980	regulatory RNA binding	10/715	58/18639	0.172413793103448	4.49457439112612	6.38086900867416e-05	0.00361715511929216
GO:0008135	translation factor activity, RNA binding	12/715	83/18639	0.144578313253012	3.76894430870334	7.37877161942237e-05	0.00384170042100897
GO:0042288	MHC class I protein binding	6/715	20/18639	0.3	7.82055944055944	7.62410226881603e-05	0.00384170042100897
GO:0180051	translation factor activity	12/715	84/18639	0.142857142857143	3.72407592407592	8.31303443210124e-05	0.00396838012100833
GO:0140104	molecular carrier activity	23/715	249/18639	0.0923694779116466	2.40793664167158	9.48618493695476e-05	0.00430198486890898
GO:0140597	protein carrier chaperone	19/715	188/18639	0.101063829787234	2.63458562713882	0.000117155790933402	0.00506001439888551
GO:0019887	protein kinase regulator activity	23/715	255/18639	0.0901960784313725	2.35127930892637	0.000135643683875572	0.00559221914887016
GO:0003712	transcription coregulator activity	36/715	495/18639	0.0727272727272727	1.89589319771138	0.000192189127096702	0.00757893644681343
GO:0140297	DNA-binding transcription factor binding	35/715	488/18639	0.0717213114754098	1.86966926516107	0.000304946431051904	0.0115244338735032
GO:0031720	haptoglobin binding	4/715	10/18639	0.4	10.4274125874126	0.000374739411898322	0.0130726402535299
GO:0032395	MHC class II receptor activity	4/715	10/18639	0.4	10.4274125874126	0.000374739411898322	0.0130726402535299
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	27/715	349/18639	0.0773638968481375	2.0167631795139	0.000460832788192851	0.0149876666605875
GO:0003746	translation elongation factor activity	5/715	18/18639	0.277777777777778	7.24125874125874	0.000462684307052314	0.0149876666605875
GO:0060590	ATPase regulator activity	8/715	49/18639	0.163265306122449	4.25608677037248	0.000504759971606703	0.0157868032499062
GO:0042608	T cell receptor binding	4/715	11/18639	0.363636363636364	9.4794659885569	0.000571040971080088	0.0172644720256547
GO:0003724	RNA helicase activity	10/715	77/18639	0.12987012987013	3.38552356734175	0.000697700192637381	0.0204133572491002
GO:0019207	kinase regulator activity	23/715	287/18639	0.0801393728222996	2.08911576228649	0.000734445979295403	0.0208169532256541
GO:0001968	fibronectin binding	6/715	30/18639	0.2	5.21370629370629	0.000841996485634735	0.0221718873436489
GO:0042287	MHC protein binding	7/715	41/18639	0.170731707317073	4.45072488487123	0.000854861005121449	0.0221718873436489
GO:0008186	ATP-dependent activity, acting on RNA	10/715	79/18639	0.126582278481013	3.29981410994069	0.000855585509402106	0.0221718873436489
GO:0005126	cytokine receptor binding	22/715	275/18639	0.08	2.08548251748252	0.000970469019237322	0.0237563172888649
GO:0017069	snRNA binding	8/715	54/18639	0.148148148148148	3.86200466200466	0.000984239918462472	0.0237563172888649
GO:0140375	immune receptor activity	15/715	156/18639	0.0961538461538462	2.50658956428187	0.00099530326017295	0.0237563172888649
GO:0001618	virus receptor activity	10/715	81/18639	0.123456790123457	3.21833721833722	0.00104168450973943	0.0242258423162477
GO:0140272	exogenous protein binding	10/715	82/18639	0.121951219512195	3.17908920347945	0.00114644563591778	0.0253670754038106
GO:0048156	tau protein binding	7/715	43/18639	0.162790697674419	4.24371442510977	0.00114669249344679	0.0253670754038106
GO:0045296	cadherin binding	25/715	334/18639	0.0748502994011976	1.95123738536912	0.00117752041419649	0.0254288337065765
GO:0061133	endopeptidase activator activity	5/715	22/18639	0.227272727272727	5.92466624284806	0.00125210535973858	0.0264106874716953
GO:0003689	DNA clamp loader activity	15/715	160/18639	0.09375	2.44392482517483	0.00128728638822514	0.0265356535027319
GO:0016504	peptidase activator activity	8/715	57/18639	0.140350877192982	3.65874125874126	0.00141335574664165	0.028085925310849
GO:0140311	protein sequestering activity	6/715	33/18639	0.181818181818182	4.73973299427845	0.00142442399591958	0.028085925310849
GO:0016887	ATP hydrolysis activity	29/715	417/18639	0.0695443645083933	1.81291945464607	0.00155720000357004	0.0298532881346207
GO:0005344	oxygen carrier activity	4/715	14/18639	0.285714285714286	7.44815184815185	0.00157988735442315	0.0298532881346207
GO:0035035	histone acetyltransferase binding	5/715	24/18639	0.208333333333333	5.43094405594406	0.00189669688519278	0.0347272561366826
GO:0000510	H3-H4 histone complex chaperone activity	14/715	151/18639	0.0927152317880795	2.41694993747974	0.00204458392132606	0.0347272561366826
GO:0140584	chromatin extrusion motor activity	14/715	151/18639	0.0927152317880795	2.41694993747974	0.00204458392132606	0.0347272561366826
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	14/715	151/18639	0.0927152317880795	2.41694993747974	0.00204458392132606	0.0347272561366826
GO:0140849	ATP-dependent H2AZ histone chaperone activity	14/715	151/18639	0.0927152317880795	2.41694993747974	0.00204458392132606	0.0347272561366826
GO:0140776	protein-containing complex destabilizing activity	4/715	15/18639	0.266666666666667	6.95160839160839	0.00208949342488373	0.0347272561366826
GO:0015616	DNA translocase activity	14/715	152/18639	0.0921052631578947	2.40104895104895	0.00217476768371354	0.0347272561366826
GO:0140674	ATP-dependent histone chaperone activity	14/715	152/18639	0.0921052631578947	2.40104895104895	0.00217476768371354	0.0347272561366826
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	7/715	48/18639	0.145833333333333	3.80166083916084	0.00222070656662358	0.0347272561366826
GO:0140693	molecular condensate scaffold activity	7/715	48/18639	0.145833333333333	3.80166083916084	0.00222070656662358	0.0347272561366826
GO:0061775	cohesin loader activity	14/715	153/18639	0.0915032679738562	2.38535582064994	0.00231172885240927	0.035537933375173
GO:0017070	U6 snRNA binding	4/715	16/18639	0.25	6.51713286713287	0.00270218226322138	0.0408479885456966
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/715	26/18639	0.192307692307692	5.01317912856374	0.00275526641402275	0.0409676497953875
GO:0003735	structural constituent of ribosome	15/715	175/18639	0.0857142857142857	2.23444555444555	0.00309841014696488	0.0447404733518965
GO:0140658	ATP-dependent chromatin remodeler activity	14/715	158/18639	0.0886075949367089	2.30986987695848	0.00310766242686822	0.0447404733518965
GO:0140296	general transcription initiation factor binding	7/715	53/18639	0.132075471698113	3.4430135901834	0.00394261152633754	0.0558741977248148
GO:0140713	histone chaperone activity	14/715	164/18639	0.0853658536585366	2.22536244243561	0.0043454833929754	0.0592483253033268
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	8/715	68/18639	0.117647058823529	3.06688605512135	0.0043766679110506	0.0592483253033268
GO:1990841	promoter-specific chromatin binding	8/715	68/18639	0.117647058823529	3.06688605512135	0.0043766679110506	0.0592483253033268
GO:0008137	NADH dehydrogenase (ubiquinone) activity	6/715	41/18639	0.146341463414634	3.81490704417534	0.00446193815778428	0.0595143810163286
GO:0003713	transcription coactivator activity	19/715	256/18639	0.07421875	1.93477381993007	0.00477388011850416	0.0620850626867958
GO:0004860	protein kinase inhibitor activity	9/715	84/18639	0.107142857142857	2.79305694305694	0.0048407687761507	0.0620850626867958
GO:0140313	molecular sequestering activity	7/715	55/18639	0.127272727272727	3.31781309599491	0.00486002144516262	0.0620850626867958
GO:0097110	scaffold protein binding	8/715	70/18639	0.114285714285714	2.97926073926074	0.00522917147660356	0.0653681526259487
GO:0035925	mRNA 3'-UTR AU-rich region binding	5/715	30/18639	0.166666666666667	4.34475524475524	0.00526116333152619	0.0653681526259487
GO:0003714	transcription corepressor activity	16/715	204/18639	0.0784313725490196	2.04459070341423	0.00547800834435793	0.066644393258291
GO:0005031	tumor necrosis factor receptor activity	3/715	10/18639	0.3	7.82055944055944	0.00551083736975946	0.066644393258291
GO:0004601	peroxidase activity	7/715	57/18639	0.12280701754386	3.2013986013986	0.00592942221804739	0.0707629730495919
GO:0005525	GTP binding	25/715	378/18639	0.0661375661375661	1.72410922410922	0.00600991548180965	0.0707921213246929
GO:0001046	core promoter sequence-specific DNA binding	6/715	44/18639	0.136363636363636	3.55479974570884	0.00635879481685451	0.0709965038855377
GO:0003954	NADH dehydrogenase activity	6/715	44/18639	0.136363636363636	3.55479974570884	0.00635879481685451	0.0709965038855377
GO:0016004	phospholipase activator activity	4/715	20/18639	0.2	5.21370629370629	0.00636890805385991	0.0709965038855377
GO:0019001	guanyl nucleotide binding	26/715	400/18639	0.065	1.69445454545455	0.00641864753981708	0.0709965038855377
GO:0032561	guanyl ribonucleotide binding	26/715	400/18639	0.065	1.69445454545455	0.00641864753981708	0.0709965038855377
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	7/715	58/18639	0.120689655172414	3.14620207378828	0.00652565724706487	0.0713104954588897
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	7/715	59/18639	0.11864406779661	3.09287661491051	0.00716534864302197	0.0773687049907253
GO:0043522	leucine zipper domain binding	3/715	11/18639	0.272727272727273	7.10959949141767	0.00736326101926421	0.0785703264055605
GO:0019210	kinase inhibitor activity	9/715	90/18639	0.1	2.60685314685315	0.00759033010718237	0.0800515047350513
GO:0003725	double-stranded RNA binding	8/715	75/18639	0.106666666666667	2.78064335664336	0.0079140587362965	0.0825063364807003
GO:0140098	catalytic activity, acting on RNA	25/715	387/18639	0.0645994832041344	1.68401366075785	0.00800541121438851	0.0825103178573906
GO:0043021	ribonucleoprotein complex binding	14/715	177/18639	0.0790960451977401	2.06191774327368	0.00840507454044513	0.0856562090807161
GO:0005125	cytokine activity	17/715	234/18639	0.0726495726495727	1.89386767079075	0.00901017506539419	0.0902978833482765
GO:0016831	carboxy-lyase activity	5/715	34/18639	0.147058823529412	3.83360756890169	0.00905965533042245	0.0902978833482765
GO:0042826	histone deacetylase binding	11/715	127/18639	0.0866141732283465	2.25790430042399	0.00973072901843241	0.0959322958665021
GO:0005200	structural constituent of cytoskeleton	10/715	112/18639	0.0892857142857143	2.32754745254745	0.0109359861555672	0.10589561022132
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/715	13/18639	0.230769230769231	6.01581495427649	0.0120539587514549	0.10589561022132
GO:0005035	death receptor activity	3/715	13/18639	0.230769230769231	6.01581495427649	0.0120539587514549	0.10589561022132
GO:0097157	pre-mRNA intronic binding	3/715	13/18639	0.230769230769231	6.01581495427649	0.0120539587514549	0.10589561022132
GO:0033192	calmodulin-dependent protein phosphatase activity	8/715	81/18639	0.0987654320987654	2.57466977466977	0.012368071259986	0.10589561022132
GO:0140791	histone H2AXS140 phosphatase activity	8/715	81/18639	0.0987654320987654	2.57466977466977	0.012368071259986	0.10589561022132
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	8/715	81/18639	0.0987654320987654	2.57466977466977	0.012368071259986	0.10589561022132
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	8/715	81/18639	0.0987654320987654	2.57466977466977	0.012368071259986	0.10589561022132
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	8/715	81/18639	0.0987654320987654	2.57466977466977	0.012368071259986	0.10589561022132
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	8/715	81/18639	0.0987654320987654	2.57466977466977	0.012368071259986	0.10589561022132
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	8/715	81/18639	0.0987654320987654	2.57466977466977	0.012368071259986	0.10589561022132
GO:1990439	MAP kinase serine/threonine phosphatase activity	8/715	81/18639	0.0987654320987654	2.57466977466977	0.012368071259986	0.10589561022132
GO:0048027	mRNA 5'-UTR binding	4/715	24/18639	0.166666666666667	4.34475524475524	0.0123758927050274	0.10589561022132
GO:0060229	lipase activator activity	4/715	24/18639	0.166666666666667	4.34475524475524	0.0123758927050274	0.10589561022132
GO:0004725	protein tyrosine phosphatase activity	9/715	98/18639	0.0918367346938776	2.39404880833452	0.0129373177610302	0.107331525308954
GO:0003743	translation initiation factor activity	6/715	51/18639	0.117647058823529	3.06688605512135	0.0129565950255346	0.107331525308954
GO:0016830	carbon-carbon lyase activity	6/715	51/18639	0.117647058823529	3.06688605512135	0.0129565950255346	0.107331525308954
GO:0001221	transcription coregulator binding	10/715	115/18639	0.0869565217391304	2.26682882335056	0.0130170537860914	0.107331525308954
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	8/715	82/18639	0.0975609756097561	2.54327136278356	0.0132595343949308	0.107378550858949
GO:0033549	MAP kinase phosphatase activity	8/715	82/18639	0.0975609756097561	2.54327136278356	0.0132595343949308	0.107378550858949
GO:0005080	protein kinase C binding	6/715	52/18639	0.115384615384615	3.00790747713825	0.0141853148535792	0.112953858475707
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	8/715	83/18639	0.0963855421686747	2.51262953913556	0.0141970671072003	0.112953858475707
GO:0070742	C2H2 zinc finger domain binding	3/715	14/18639	0.214285714285714	5.58611388611389	0.014910523677918	0.117598651964101
GO:0017018	myosin phosphatase activity	8/715	84/18639	0.0952380952380952	2.48271728271728	0.0151819406157318	0.118707070159213
GO:0008094	ATP-dependent activity, acting on DNA	15/715	210/18639	0.0714285714285714	1.86203796203796	0.0156833147126435	0.121579200379211
GO:0002039	p53 binding	7/715	69/18639	0.101449275362319	2.64463362724232	0.016349326842907	0.125091546596478
GO:0004386	helicase activity	12/715	155/18639	0.0774193548387097	2.01820888788631	0.0164122315821178	0.125091546596478
GO:0140463	chromatin-protein adaptor activity	6/715	54/18639	0.111111111111111	2.8965034965035	0.0168816032439949	0.127596784519195
GO:0016209	antioxidant activity	8/715	86/18639	0.0930232558139535	2.4249796714913	0.0172987121609478	0.129668858925451
GO:0000774	adenyl-nucleotide exchange factor activity	3/715	15/18639	0.2	5.21370629370629	0.0181157812411766	0.131448108685978
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	3/715	15/18639	0.2	5.21370629370629	0.0181157812411766	0.131448108685978
GO:0031386	protein tag activity	3/715	15/18639	0.2	5.21370629370629	0.0181157812411766	0.131448108685978
GO:0141047	molecular tag activity	3/715	15/18639	0.2	5.21370629370629	0.0181157812411766	0.131448108685978
GO:0001671	ATPase activator activity	4/715	27/18639	0.148148148148148	3.86200466200466	0.0186752892919386	0.134432439585622
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	8/715	89/18639	0.0898876404494382	2.34323878368822	0.0208596700295962	0.147518331223415
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	8/715	89/18639	0.0898876404494382	2.34323878368822	0.0208596700295962	0.147518331223415
GO:0051537	2 iron, 2 sulfur cluster binding	4/715	28/18639	0.142857142857143	3.72407592407592	0.0211437519945357	0.147518331223415
GO:0097718	disordered domain specific binding	4/715	28/18639	0.142857142857143	3.72407592407592	0.0211437519945357	0.147518331223415
GO:0030275	LRR domain binding	3/715	16/18639	0.1875	4.88784965034965	0.0216727656207047	0.150054949755566
GO:0140793	histone H2AXY142 phosphatase activity	8/715	90/18639	0.0888888888888889	2.3172027972028	0.0221542397781244	0.152226480899688
GO:0004629	phospholipase C activity	4/715	29/18639	0.137931034482759	3.59565951290089	0.023802810629841	0.162324430385457
GO:0036002	pre-mRNA binding	6/715	59/18639	0.101694915254237	2.65103709849473	0.0251157255513482	0.168199897636478
GO:0004549	tRNA-specific ribonuclease activity	3/715	17/18639	0.176470588235294	4.60032908268202	0.0255824715739717	0.168199897636478
GO:0005092	GDP-dissociation inhibitor activity	3/715	17/18639	0.176470588235294	4.60032908268202	0.0255824715739717	0.168199897636478
GO:1990226	histone methyltransferase binding	3/715	17/18639	0.176470588235294	4.60032908268202	0.0255824715739717	0.168199897636478
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	10/715	128/18639	0.078125	2.03660402097902	0.0255916051530695	0.168199897636478
GO:0030547	signaling receptor inhibitor activity	5/715	44/18639	0.113636363636364	2.96233312142403	0.0258903236473291	0.168939018331852
GO:0048019	receptor antagonist activity	4/715	30/18639	0.133333333333333	3.4758041958042	0.0266553717526587	0.172688729854725
GO:0008009	chemokine activity	5/715	45/18639	0.111111111111111	2.8965034965035	0.028238544897215	0.181647944835277
GO:0005164	tumor necrosis factor receptor binding	4/715	31/18639	0.129032258064516	3.36368147981051	0.0297037855414581	0.187976098074168
GO:0016411	acylglycerol O-acyltransferase activity	4/715	31/18639	0.129032258064516	3.36368147981051	0.0297037855414581	0.187976098074168
GO:0050811	GABA receptor binding	3/715	18/18639	0.166666666666667	4.34475524475524	0.0298440552620509	0.187976098074168
GO:0004896	cytokine receptor activity	8/715	96/18639	0.0833333333333333	2.17237762237762	0.0311277985977907	0.194683828208684
GO:0004857	enzyme inhibitor activity	24/715	416/18639	0.0576923076923077	1.50395373856912	0.0313383009023901	0.194683828208684
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/715	32/18639	0.125	3.25856643356643	0.0329498573326278	0.201929193247929
GO:0051059	NF-kappaB binding	4/715	32/18639	0.125	3.25856643356643	0.0329498573326278	0.201929193247929
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	27/715	484/18639	0.0557851239669422	1.45423625960816	0.0338380811670195	0.205980802808636
GO:0009055	electron transfer activity	9/715	116/18639	0.0775862068965517	2.02255847600675	0.0344519279710448	0.206958303994524
GO:0097001	ceramide binding	3/715	19/18639	0.157894736842105	4.11608391608392	0.0344550208414257	0.206958303994524
GO:0140789	histone phosphatase activity	10/715	136/18639	0.0735294117647059	1.91680378445084	0.036702963511612	0.219010446743632
GO:0022853	active monoatomic ion transmembrane transporter activity	9/715	118/18639	0.076271186440678	1.98827782387104	0.0378209166366362	0.224206348950516
GO:0001216	DNA-binding transcription activator activity	27/715	491/18639	0.054989816700611	1.43350376710866	0.0393310105903671	0.230620219828808
GO:0043024	ribosomal small subunit binding	3/715	20/18639	0.15	3.91027972027972	0.0394113936862902	0.230620219828808
GO:0019825	oxygen binding	4/715	34/18639	0.117647058823529	3.06688605512135	0.0400395553221335	0.232794081263943
GO:0030295	protein kinase activator activity	10/715	139/18639	0.0719424460431655	1.87543391859939	0.0416197674401909	0.239419923407288
GO:0032813	tumor necrosis factor receptor superfamily binding	5/715	50/18639	0.1	2.60685314685315	0.0419710780835267	0.239419923407288
GO:0048020	CCR chemokine receptor binding	5/715	50/18639	0.1	2.60685314685315	0.0419710780835267	0.239419923407288
GO:0004540	RNA nuclease activity	9/715	121/18639	0.0743801652892562	1.93898167947755	0.0432845068408622	0.245369048154138
GO:0016229	steroid dehydrogenase activity	4/715	35/18639	0.114285714285714	2.97926073926074	0.0438841987527179	0.247223405395746
GO:0004722	protein serine/threonine phosphatase activity	8/715	103/18639	0.0776699029126214	2.02474030823545	0.0444118096518987	0.247256390972056
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	3/715	21/18639	0.142857142857143	3.72407592407592	0.0447078810577918	0.247256390972056
GO:0035613	RNA stem-loop binding	3/715	21/18639	0.142857142857143	3.72407592407592	0.0447078810577918	0.247256390972056
GO:0030544	Hsp70 protein binding	5/715	51/18639	0.0980392156862745	2.55573837926779	0.0451248262420042	0.24804980243332
GO:0140517	protein-RNA adaptor activity	3/715	22/18639	0.136363636363636	3.55479974570884	0.0503380209912921	0.275039668910253
GO:0016651	oxidoreductase activity, acting on NAD(P)H	7/715	88/18639	0.0795454545454545	2.07363318499682	0.052110384885278	0.276252095313153
GO:0043394	proteoglycan binding	4/715	37/18639	0.108108108108108	2.81821961821962	0.0521719837752867	0.276252095313153
GO:0003924	GTPase activity	19/715	331/18639	0.0574018126888218	1.4963809604293	0.0532731748029076	0.276252095313153
GO:0061134	peptidase regulator activity	14/715	226/18639	0.0619469026548673	1.61486478123646	0.0536796866873362	0.276252095313153
GO:0001094	TFIID-class transcription factor complex binding	2/715	10/18639	0.2	5.21370629370629	0.0539102765936363	0.276252095313153
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/715	10/18639	0.2	5.21370629370629	0.0539102765936363	0.276252095313153
GO:0004090	carbonyl reductase (NADPH) activity	2/715	10/18639	0.2	5.21370629370629	0.0539102765936363	0.276252095313153
GO:0008140	cAMP response element binding protein binding	2/715	10/18639	0.2	5.21370629370629	0.0539102765936363	0.276252095313153
GO:0030957	Tat protein binding	2/715	10/18639	0.2	5.21370629370629	0.0539102765936363	0.276252095313153
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	2/715	10/18639	0.2	5.21370629370629	0.0539102765936363	0.276252095313153
GO:0141109	transporter activator activity	2/715	10/18639	0.2	5.21370629370629	0.0539102765936363	0.276252095313153
GO:0015399	primary active transmembrane transporter activity	11/715	166/18639	0.0662650602409639	1.7274328081557	0.0552465892414127	0.280782647981176
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	5/715	54/18639	0.0925925925925926	2.41375291375291	0.0554135545629884	0.280782647981176
GO:0042171	lysophosphatidic acid acyltransferase activity	3/715	23/18639	0.130434782608696	3.40024323502584	0.0562943201297277	0.282093637335155
GO:0071617	lysophospholipid acyltransferase activity	3/715	23/18639	0.130434782608696	3.40024323502584	0.0562943201297277	0.282093637335155
GO:0005518	collagen binding	6/715	72/18639	0.0833333333333333	2.17237762237762	0.0577792914399527	0.28601839702417
GO:0042379	chemokine receptor binding	6/715	72/18639	0.0833333333333333	2.17237762237762	0.0577792914399527	0.28601839702417
GO:0031490	chromatin DNA binding	9/715	128/18639	0.0703125	1.83294361888112	0.0580235777866012	0.28601839702417
GO:0005096	GTPase activator activity	16/715	271/18639	0.0590405904059041	1.53910148891699	0.0587533689149036	0.286346203904694
GO:0019209	kinase activator activity	10/715	148/18639	0.0675675675675676	1.76138726138726	0.0590110163118435	0.286346203904694
GO:0030695	GTPase regulator activity	26/715	489/18639	0.0531697341513292	1.38605688789738	0.0590371997025112	0.286346203904694
GO:0051015	actin filament binding	13/715	209/18639	0.062200956937799	1.62148760330579	0.0598099150267406	0.288551026219435
GO:0060589	nucleoside-triphosphatase regulator activity	26/715	490/18639	0.0530612244897959	1.38322820037106	0.0601875440301109	0.288836520821749
GO:0004521	RNA endonuclease activity	6/715	73/18639	0.0821917808219178	2.14261902481081	0.0610117426389967	0.291250792492473
GO:0001091	RNA polymerase II general transcription initiation factor binding	3/715	24/18639	0.125	3.25856643356643	0.0625683811903991	0.295570425727563
GO:0070300	phosphatidic acid binding	3/715	24/18639	0.125	3.25856643356643	0.0625683811903991	0.295570425727563
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/715	11/18639	0.181818181818182	4.73973299427845	0.0642540578323856	0.298863745917814
GO:0070697	activin receptor binding	2/715	11/18639	0.181818181818182	4.73973299427845	0.0642540578323856	0.298863745917814
GO:0070990	snRNP binding	2/715	11/18639	0.181818181818182	4.73973299427845	0.0642540578323856	0.298863745917814
GO:0043022	ribosome binding	8/715	112/18639	0.0714285714285714	1.86203796203796	0.0663234052468508	0.306914941627009
GO:0001530	lipopolysaccharide binding	4/715	41/18639	0.0975609756097561	2.54327136278356	0.0711073590960765	0.326524222082868
GO:0004526	ribonuclease P activity	2/715	12/18639	0.166666666666667	4.34475524475524	0.0751967100216391	0.326524222082868
GO:0031543	peptidyl-proline dioxygenase activity	2/715	12/18639	0.166666666666667	4.34475524475524	0.0751967100216391	0.326524222082868
GO:0035259	nuclear glucocorticoid receptor binding	2/715	12/18639	0.166666666666667	4.34475524475524	0.0751967100216391	0.326524222082868
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	2/715	12/18639	0.166666666666667	4.34475524475524	0.0751967100216391	0.326524222082868
GO:1990247	N6-methyladenosine-containing RNA reader activity	2/715	12/18639	0.166666666666667	4.34475524475524	0.0751967100216391	0.326524222082868
GO:0070063	RNA polymerase binding	5/715	59/18639	0.0847457627118644	2.20919758207894	0.0753177890456673	0.326524222082868
GO:0004435	phosphatidylinositol phospholipase C activity	3/715	26/18639	0.115384615384615	3.00790747713825	0.0760323777073412	0.326524222082868
GO:0008143	poly(A) binding	3/715	26/18639	0.115384615384615	3.00790747713825	0.0760323777073412	0.326524222082868
GO:0008157	protein phosphatase 1 binding	3/715	26/18639	0.115384615384615	3.00790747713825	0.0760323777073412	0.326524222082868
GO:0008198	ferrous iron binding	3/715	26/18639	0.115384615384615	3.00790747713825	0.0760323777073412	0.326524222082868
GO:0070412	R-SMAD binding	3/715	26/18639	0.115384615384615	3.00790747713825	0.0760323777073412	0.326524222082868
GO:0097602	cullin family protein binding	3/715	26/18639	0.115384615384615	3.00790747713825	0.0760323777073412	0.326524222082868
GO:0004402	histone acetyltransferase activity	4/715	42/18639	0.0952380952380952	2.48271728271728	0.0763209868595017	0.326524222082868
GO:0042056	chemoattractant activity	4/715	42/18639	0.0952380952380952	2.48271728271728	0.0763209868595017	0.326524222082868
GO:0051879	Hsp90 protein binding	4/715	42/18639	0.0952380952380952	2.48271728271728	0.0763209868595017	0.326524222082868
GO:0002020	protease binding	9/715	136/18639	0.0661764705882353	1.72512340600576	0.0784200500370499	0.333929508843212
GO:0005385	zinc ion transmembrane transporter activity	3/715	27/18639	0.111111111111111	2.8965034965035	0.0832020137592665	0.350996402230952
GO:0035255	ionotropic glutamate receptor binding	3/715	27/18639	0.111111111111111	2.8965034965035	0.0832020137592665	0.350996402230952
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	5/715	61/18639	0.0819672131147541	2.13676487446979	0.0842304469929256	0.353085512103572
GO:0016829	lyase activity	12/715	200/18639	0.06	1.56411188811189	0.0844758060931367	0.353085512103572
GO:0008035	high-density lipoprotein particle binding	2/715	13/18639	0.153846153846154	4.010543302851	0.0866772102525817	0.358978217804071
GO:0019855	calcium channel inhibitor activity	2/715	13/18639	0.153846153846154	4.010543302851	0.0866772102525817	0.358978217804071
GO:0032182	ubiquitin-like protein binding	8/715	120/18639	0.0666666666666667	1.7379020979021	0.0905654503273132	0.370354268874451
GO:0046625	sphingolipid binding	3/715	28/18639	0.107142857142857	2.79305694305694	0.0906490051710343	0.370354268874451
GO:0051019	mitogen-activated protein kinase binding	3/715	28/18639	0.107142857142857	2.79305694305694	0.0906490051710343	0.370354268874451
GO:0003697	single-stranded DNA binding	8/715	121/18639	0.0661157024793388	1.72353927064671	0.0939127737599822	0.38196809775921
GO:0061135	endopeptidase regulator activity	11/715	184/18639	0.0597826086956522	1.55844481605351	0.0974562339831575	0.392127277785858
GO:0008191	metalloendopeptidase inhibitor activity	2/715	14/18639	0.142857142857143	3.72407592407592	0.0986383246816924	0.392127277785858
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/715	14/18639	0.142857142857143	3.72407592407592	0.0986383246816924	0.392127277785858
GO:0043176	amine binding	2/715	14/18639	0.142857142857143	3.72407592407592	0.0986383246816924	0.392127277785858
GO:0098847	sequence-specific single stranded DNA binding	2/715	14/18639	0.142857142857143	3.72407592407592	0.0986383246816924	0.392127277785858
GO:0030291	protein serine/threonine kinase inhibitor activity	4/715	46/18639	0.0869565217391304	2.26682882335056	0.0990045717893731	0.392127277785858
GO:0015078	proton transmembrane transporter activity	11/715	185/18639	0.0594594594594595	1.55002079002079	0.100246448242009	0.395319689371748
GO:0019955	cytokine binding	9/715	144/18639	0.0625	1.62928321678322	0.102684340645682	0.403180506344733
GO:0019843	rRNA binding	5/715	65/18639	0.0769230769230769	2.0052716514255	0.103631296508155	0.403405948209855
GO:0038024	cargo receptor activity	5/715	65/18639	0.0769230769230769	2.0052716514255	0.103631296508155	0.403405948209855
GO:0061733	protein-lysine-acetyltransferase activity	4/715	47/18639	0.0851063829787234	2.21859842285374	0.105113949548487	0.407428855728538
GO:0042578	phosphoric ester hydrolase activity	19/715	363/18639	0.0523415977961433	1.36446858926198	0.106734387079257	0.411949315237812
GO:0004129	cytochrome-c oxidase activity	2/715	15/18639	0.133333333333333	3.4758041958042	0.111026408287925	0.423113245030035
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/715	15/18639	0.133333333333333	3.4758041958042	0.111026408287925	0.423113245030035
GO:0048531	beta-1,3-galactosyltransferase activity	2/715	15/18639	0.133333333333333	3.4758041958042	0.111026408287925	0.423113245030035
GO:0050840	extracellular matrix binding	5/715	67/18639	0.0746268656716418	1.94541279615906	0.11409092682812	0.432972680473243
GO:0035254	glutamate receptor binding	4/715	49/18639	0.0816326530612245	2.12804338518624	0.117829056362713	0.445295642170753
GO:0030145	manganese ion binding	5/715	68/18639	0.0735294117647059	1.91680378445084	0.119503131436604	0.449748299639004
GO:0070717	poly-purine tract binding	3/715	32/18639	0.09375	2.44392482517483	0.122979614441924	0.456417200998379
GO:0071813	lipoprotein particle binding	3/715	32/18639	0.09375	2.44392482517483	0.122979614441924	0.456417200998379
GO:0071814	protein-lipid complex binding	3/715	32/18639	0.09375	2.44392482517483	0.122979614441924	0.456417200998379
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/715	16/18639	0.125	3.25856643356643	0.123791214383243	0.456417200998379
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/715	16/18639	0.125	3.25856643356643	0.123791214383243	0.456417200998379
GO:0008080	N-acetyltransferase activity	5/715	69/18639	0.072463768115942	1.8890240194588	0.125033748967655	0.459132025561389
GO:0008201	heparin binding	10/715	172/18639	0.0581395348837209	1.51561229468206	0.125972766151479	0.460714914916902
GO:0071889	14-3-3 protein binding	3/715	33/18639	0.0909090909090909	2.36986649713922	0.13163808976557	0.479500993644064
GO:0061630	ubiquitin protein ligase activity	18/715	353/18639	0.0509915014164306	1.32927355930189	0.135261971214412	0.483094716249036
GO:0004721	phosphoprotein phosphatase activity	10/715	175/18639	0.0571428571428571	1.48963036963037	0.13644908619482	0.483094716249036
GO:0004659	prenyltransferase activity	2/715	17/18639	0.117647058823529	3.06688605512135	0.136885713424479	0.483094716249036
GO:0008429	phosphatidylethanolamine binding	2/715	17/18639	0.117647058823529	3.06688605512135	0.136885713424479	0.483094716249036
GO:0030169	low-density lipoprotein particle binding	2/715	17/18639	0.117647058823529	3.06688605512135	0.136885713424479	0.483094716249036
GO:0032977	membrane insertase activity	2/715	17/18639	0.117647058823529	3.06688605512135	0.136885713424479	0.483094716249036
GO:0048038	quinone binding	2/715	17/18639	0.117647058823529	3.06688605512135	0.136885713424479	0.483094716249036
GO:0051787	misfolded protein binding	2/715	17/18639	0.117647058823529	3.06688605512135	0.136885713424479	0.483094716249036
GO:0005539	glycosaminoglycan binding	13/715	242/18639	0.0537190082644628	1.40037565740045	0.140116349428143	0.492029864511038
GO:0030332	cyclin binding	3/715	34/18639	0.0882352941176471	2.30016454134101	0.140502464066548	0.492029864511038
GO:0004842	ubiquitin-protein transferase activity	22/715	449/18639	0.0489977728285078	1.27729998286791	0.144281557828864	0.494791286982984
GO:0016755	aminoacyltransferase activity	24/715	496/18639	0.0483870967741935	1.26138055492894	0.145054229160246	0.494791286982984
GO:0005003	ephrin receptor activity	4/715	53/18639	0.0754716981132075	1.96743633724766	0.145109682841757	0.494791286982984
GO:0005005	transmembrane-ephrin receptor activity	4/715	53/18639	0.0754716981132075	1.96743633724766	0.145109682841757	0.494791286982984
GO:0005246	calcium channel regulator activity	4/715	53/18639	0.0754716981132075	1.96743633724766	0.145109682841757	0.494791286982984
GO:0016860	intramolecular oxidoreductase activity	4/715	53/18639	0.0754716981132075	1.96743633724766	0.145109682841757	0.494791286982984
GO:0034212	protein N-acetyltransferase activity	4/715	53/18639	0.0754716981132075	1.96743633724766	0.145109682841757	0.494791286982984
GO:0043539	protein serine/threonine kinase activator activity	5/715	73/18639	0.0684931506849315	1.785515854009	0.148287991965362	0.503176033796003
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/715	18/18639	0.111111111111111	2.8965034965035	0.150265920694782	0.503176033796003
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	2/715	18/18639	0.111111111111111	2.8965034965035	0.150265920694782	0.503176033796003
GO:1901611	phosphatidylglycerol binding	2/715	18/18639	0.111111111111111	2.8965034965035	0.150265920694782	0.503176033796003
GO:0140097	catalytic activity, acting on DNA	17/715	336/18639	0.0505952380952381	1.31894355644356	0.150342563570801	0.503176033796003
GO:0016410	N-acyltransferase activity	6/715	94/18639	0.0638297872340425	1.66394881714031	0.152382609133535	0.508128773838664
GO:0031491	nucleosome binding	5/715	74/18639	0.0675675675675676	1.76138726138726	0.154370501789192	0.512871960156768
GO:0016922	nuclear receptor binding	8/715	137/18639	0.0583941605839416	1.52225001276096	0.156661097265252	0.51858253729775
GO:0045505	dynein intermediate chain binding	3/715	36/18639	0.0833333333333333	2.17237762237762	0.158799686157941	0.522564601262891
GO:0019787	ubiquitin-like protein transferase activity	23/715	479/18639	0.0480167014613779	1.25172489306101	0.159523588511755	0.522564601262891
GO:0008374	O-acyltransferase activity	4/715	55/18639	0.0727272727272727	1.89589319771138	0.159592496747322	0.522564601262891
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/715	19/18639	0.105263157894737	2.74405594405594	0.163890732442236	0.530888908303958
GO:0042577	lipid phosphatase activity	2/715	19/18639	0.105263157894737	2.74405594405594	0.163890732442236	0.530888908303958
GO:0070003	threonine-type peptidase activity	2/715	19/18639	0.105263157894737	2.74405594405594	0.163890732442236	0.530888908303958
GO:0005178	integrin binding	9/715	161/18639	0.0559006211180124	1.45724710072536	0.166643345275649	0.53470502369522
GO:0016791	phosphatase activity	14/715	273/18639	0.0512820512820513	1.336847767617	0.166654130126396	0.53470502369522
GO:0098631	cell adhesion mediator activity	5/715	76/18639	0.0657894736842105	1.71503496503496	0.166837399896083	0.53470502369522
GO:0001664	G protein-coupled receptor binding	15/715	297/18639	0.0505050505050505	1.31659249841068	0.170209317382948	0.543591024177233
GO:0000339	RNA cap binding	2/715	20/18639	0.1	2.60685314685315	0.177721770081786	0.557925115079845
GO:0030742	GTP-dependent protein binding	2/715	20/18639	0.1	2.60685314685315	0.177721770081786	0.557925115079845
GO:0031418	L-ascorbic acid binding	2/715	20/18639	0.1	2.60685314685315	0.177721770081786	0.557925115079845
GO:0042162	telomeric DNA binding	3/715	38/18639	0.0789473684210526	2.05804195804196	0.177773272610888	0.557925115079845
GO:0043531	ADP binding	3/715	38/18639	0.0789473684210526	2.05804195804196	0.177773272610888	0.557925115079845
GO:0004518	nuclease activity	11/715	209/18639	0.0526315789473684	1.37202797202797	0.180789986810323	0.565436269092977
GO:0043130	ubiquitin binding	6/715	100/18639	0.06	1.56411188811189	0.185860661074986	0.577092220548045
GO:0046332	SMAD binding	5/715	79/18639	0.0632911392405063	1.64990705497035	0.186244919212378	0.577092220548045
GO:0061659	ubiquitin-like protein ligase activity	18/715	372/18639	0.0483870967741935	1.26138055492894	0.186425601566237	0.577092220548045
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	7/715	122/18639	0.0573770491803279	1.49573541212885	0.188523739242006	0.581581844483178
GO:0031593	polyubiquitin modification-dependent protein binding	4/715	59/18639	0.0677966101694915	1.76735806566315	0.190023181533007	0.581581844483178
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2/715	21/18639	0.0952380952380952	2.48271728271728	0.191723232084311	0.581581844483178
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/715	21/18639	0.0952380952380952	2.48271728271728	0.191723232084311	0.581581844483178
GO:0070182	DNA polymerase binding	2/715	21/18639	0.0952380952380952	2.48271728271728	0.191723232084311	0.581581844483178
GO:0072542	protein phosphatase activator activity	2/715	21/18639	0.0952380952380952	2.48271728271728	0.191723232084311	0.581581844483178
GO:0048306	calcium-dependent protein binding	5/715	80/18639	0.0625	1.62928321678322	0.192889575713678	0.583169483907688
GO:0004532	RNA exonuclease activity	3/715	40/18639	0.075	1.95513986013986	0.197326729727719	0.584683792638438
GO:0032451	demethylase activity	3/715	40/18639	0.075	1.95513986013986	0.197326729727719	0.584683792638438
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	3/715	40/18639	0.075	1.95513986013986	0.197326729727719	0.584683792638438
GO:0001098	basal transcription machinery binding	4/715	60/18639	0.0666666666666667	1.7379020979021	0.197902893428887	0.584683792638438
GO:0001099	basal RNA polymerase II transcription machinery binding	4/715	60/18639	0.0666666666666667	1.7379020979021	0.197902893428887	0.584683792638438
GO:0004714	transmembrane receptor protein tyrosine kinase activity	4/715	60/18639	0.0666666666666667	1.7379020979021	0.197902893428887	0.584683792638438
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	4/715	60/18639	0.0666666666666667	1.7379020979021	0.197902893428887	0.584683792638438
GO:0008649	rRNA methyltransferase activity	2/715	22/18639	0.0909090909090909	2.36986649713922	0.205861753193613	0.600374952239895
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/715	22/18639	0.0909090909090909	2.36986649713922	0.205861753193613	0.600374952239895
GO:0070034	telomerase RNA binding	2/715	22/18639	0.0909090909090909	2.36986649713922	0.205861753193613	0.600374952239895
GO:0140784	metal ion sensor activity	2/715	22/18639	0.0909090909090909	2.36986649713922	0.205861753193613	0.600374952239895
GO:0004519	endonuclease activity	7/715	127/18639	0.0551181102362205	1.4368481911789	0.215557560723787	0.624285921808862
GO:0043175	RNA polymerase core enzyme binding	3/715	42/18639	0.0714285714285714	1.86203796203796	0.217366065346183	0.624285921808862
GO:0008171	O-methyltransferase activity	2/715	23/18639	0.0869565217391304	2.26682882335056	0.220106270628269	0.624285921808862
GO:0031681	G-protein beta-subunit binding	2/715	23/18639	0.0869565217391304	2.26682882335056	0.220106270628269	0.624285921808862
GO:0043274	phospholipase binding	2/715	23/18639	0.0869565217391304	2.26682882335056	0.220106270628269	0.624285921808862
GO:0140102	catalytic activity, acting on a rRNA	2/715	23/18639	0.0869565217391304	2.26682882335056	0.220106270628269	0.624285921808862
GO:0140103	catalytic activity, acting on a glycoprotein	2/715	23/18639	0.0869565217391304	2.26682882335056	0.220106270628269	0.624285921808862
GO:0004527	exonuclease activity	5/715	84/18639	0.0595238095238095	1.5516983016983	0.220255231509191	0.624285921808862
GO:0051117	ATPase binding	5/715	84/18639	0.0595238095238095	1.5516983016983	0.220255231509191	0.624285921808862
GO:0004712	protein serine/threonine/tyrosine kinase activity	3/715	43/18639	0.0697674418604651	1.81873475361847	0.227539445039416	0.642584929965261
GO:0019888	protein phosphatase regulator activity	6/715	107/18639	0.0560747663551402	1.46178681131952	0.228128277231327	0.642584929965261
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	13/715	268/18639	0.0485074626865672	1.26451831750339	0.231071214708082	0.648859417152416
GO:0005540	hyaluronic acid binding	2/715	24/18639	0.0833333333333333	2.17237762237762	0.234427896940803	0.650232729435193
GO:0019957	C-C chemokine binding	2/715	24/18639	0.0833333333333333	2.17237762237762	0.234427896940803	0.650232729435193
GO:0030215	semaphorin receptor binding	2/715	24/18639	0.0833333333333333	2.17237762237762	0.234427896940803	0.650232729435193
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/715	24/18639	0.0833333333333333	2.17237762237762	0.234427896940803	0.650232729435193
GO:0001223	transcription coactivator binding	3/715	44/18639	0.0681818181818182	1.77739987285442	0.2378005699924	0.657576576168009
GO:0004620	phospholipase activity	6/715	109/18639	0.055045871559633	1.43496503496503	0.240737621298572	0.66367484047965
GO:0008081	phosphoric diester hydrolase activity	5/715	87/18639	0.0574712643678161	1.49819146370871	0.241508607332717	0.663782748032651
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	7/715	132/18639	0.053030303030303	1.38242212333121	0.243893115592903	0.668311346956988
GO:0046915	transition metal ion transmembrane transporter activity	3/715	45/18639	0.0666666666666667	1.7379020979021	0.248138713491684	0.67361617281735
GO:0019211	phosphatase activator activity	2/715	25/18639	0.08	2.08548251748252	0.248799799221403	0.67361617281735
GO:0042974	nuclear retinoic acid receptor binding	2/715	25/18639	0.08	2.08548251748252	0.248799799221403	0.67361617281735
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/715	25/18639	0.08	2.08548251748252	0.248799799221403	0.67361617281735
GO:0016853	isomerase activity	9/715	180/18639	0.05	1.30342657342657	0.255079713719375	0.686883569447819
GO:0016500	protein-hormone receptor activity	4/715	67/18639	0.0597014925373134	1.55633023692725	0.255462887431168	0.686883569447819
GO:0003727	single-stranded RNA binding	5/715	89/18639	0.0561797752808989	1.46452423980514	0.255972046828405	0.686883569447819
GO:0030247	polysaccharide binding	2/715	26/18639	0.0769230769230769	2.0052716514255	0.263197084347574	0.702116927950735
GO:0034237	protein kinase A regulatory subunit binding	2/715	26/18639	0.0769230769230769	2.0052716514255	0.263197084347574	0.702116927950735
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	11/715	229/18639	0.0480349344978166	1.25220020154518	0.265094538634376	0.705104828567094
GO:0019838	growth factor binding	7/715	136/18639	0.0514705882352941	1.34176264911559	0.267353841966034	0.709034896676001
GO:0043495	protein-membrane adaptor activity	3/715	47/18639	0.0638297872340425	1.66394881714031	0.269004521382116	0.711332655666411
GO:0001217	DNA-binding transcription repressor activity	13/715	278/18639	0.0467625899280576	1.2190320470896	0.271273474880725	0.715247214293073
GO:0004364	glutathione transferase activity	2/715	27/18639	0.0740740740740741	1.93100233100233	0.27759668999464	0.719314487389496
GO:0005044	scavenger receptor activity	2/715	27/18639	0.0740740740740741	1.93100233100233	0.27759668999464	0.719314487389496
GO:0008320	protein transmembrane transporter activity	2/715	27/18639	0.0740740740740741	1.93100233100233	0.27759668999464	0.719314487389496
GO:0015252	proton channel activity	2/715	27/18639	0.0740740740740741	1.93100233100233	0.27759668999464	0.719314487389496
GO:0017124	SH3 domain binding	6/715	115/18639	0.0521739130434783	1.36009729401034	0.279699694965241	0.719314487389496
GO:0051213	dioxygenase activity	5/715	93/18639	0.0537634408602151	1.40153394992105	0.285479191550162	0.719314487389496
GO:0140299	molecular sensor activity	4/715	71/18639	0.0563380281690141	1.46864966019896	0.289742171568798	0.719314487389496
GO:0005004	GPI-linked ephrin receptor activity	3/715	49/18639	0.0612244897959184	1.59603253888968	0.290056684136293	0.719314487389496
GO:0005008	hepatocyte growth factor receptor activity	3/715	49/18639	0.0612244897959184	1.59603253888968	0.290056684136293	0.719314487389496
GO:0005009	insulin receptor activity	3/715	49/18639	0.0612244897959184	1.59603253888968	0.290056684136293	0.719314487389496
GO:0005011	macrophage colony-stimulating factor receptor activity	3/715	49/18639	0.0612244897959184	1.59603253888968	0.290056684136293	0.719314487389496
GO:0005018	platelet-derived growth factor alpha-receptor activity	3/715	49/18639	0.0612244897959184	1.59603253888968	0.290056684136293	0.719314487389496
GO:0005020	stem cell factor receptor activity	3/715	49/18639	0.0612244897959184	1.59603253888968	0.290056684136293	0.719314487389496
GO:0008288	boss receptor activity	3/715	49/18639	0.0612244897959184	1.59603253888968	0.290056684136293	0.719314487389496
GO:0036332	placental growth factor receptor activity	3/715	49/18639	0.0612244897959184	1.59603253888968	0.290056684136293	0.719314487389496
GO:0038062	protein tyrosine kinase collagen receptor activity	3/715	49/18639	0.0612244897959184	1.59603253888968	0.290056684136293	0.719314487389496
GO:0060175	brain-derived neurotrophic factor receptor activity	3/715	49/18639	0.0612244897959184	1.59603253888968	0.290056684136293	0.719314487389496
GO:0045499	chemorepellent activity	2/715	28/18639	0.0714285714285714	1.86203796203796	0.291977281134916	0.719314487389496
GO:0046875	ephrin receptor binding	2/715	28/18639	0.0714285714285714	1.86203796203796	0.291977281134916	0.719314487389496
GO:0046966	nuclear thyroid hormone receptor binding	2/715	28/18639	0.0714285714285714	1.86203796203796	0.291977281134916	0.719314487389496
GO:0141052	histone H3 demethylase activity	2/715	28/18639	0.0714285714285714	1.86203796203796	0.291977281134916	0.719314487389496
GO:0019208	phosphatase regulator activity	6/715	117/18639	0.0512820512820513	1.336847767617	0.29300018800788	0.719314487389496
GO:0005006	epidermal growth factor receptor activity	3/715	50/18639	0.06	1.56411188811189	0.300628893615204	0.719314487389496
GO:0005007	fibroblast growth factor receptor activity	3/715	50/18639	0.06	1.56411188811189	0.300628893615204	0.719314487389496
GO:0005017	platelet-derived growth factor receptor activity	3/715	50/18639	0.06	1.56411188811189	0.300628893615204	0.719314487389496
GO:0005019	platelet-derived growth factor beta-receptor activity	3/715	50/18639	0.06	1.56411188811189	0.300628893615204	0.719314487389496
GO:0051861	glycolipid binding	2/715	29/18639	0.0689655172413793	1.79782975645045	0.306319151765792	0.719314487389496
GO:0016407	acetyltransferase activity	5/715	96/18639	0.0520833333333333	1.35773601398601	0.308007797931799	0.719314487389496
GO:0005010	insulin-like growth factor receptor activity	3/715	51/18639	0.0588235294117647	1.53344302756067	0.311219800247625	0.719314487389496
GO:0005021	vascular endothelial growth factor receptor activity	3/715	51/18639	0.0588235294117647	1.53344302756067	0.311219800247625	0.719314487389496
GO:0005030	neurotrophin receptor activity	3/715	51/18639	0.0588235294117647	1.53344302756067	0.311219800247625	0.719314487389496
GO:0005048	signal sequence binding	3/715	51/18639	0.0588235294117647	1.53344302756067	0.311219800247625	0.719314487389496
GO:0019903	protein phosphatase binding	7/715	144/18639	0.0486111111111111	1.26722027972028	0.31590030068178	0.719314487389496
GO:0005201	extracellular matrix structural constituent	8/715	168/18639	0.0476190476190476	1.24135864135864	0.317135003634265	0.719314487389496
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/715	30/18639	0.0666666666666667	1.7379020979021	0.32060413161868	0.719314487389496
GO:0008187	poly-pyrimidine tract binding	2/715	30/18639	0.0666666666666667	1.7379020979021	0.32060413161868	0.719314487389496
GO:0015215	nucleotide transmembrane transporter activity	2/715	30/18639	0.0666666666666667	1.7379020979021	0.32060413161868	0.719314487389496
GO:0032452	histone demethylase activity	2/715	30/18639	0.0666666666666667	1.7379020979021	0.32060413161868	0.719314487389496
GO:0033612	receptor serine/threonine kinase binding	2/715	30/18639	0.0666666666666667	1.7379020979021	0.32060413161868	0.719314487389496
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0005131	growth hormone receptor binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0005528	FK506 binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0008190	eukaryotic initiation factor 4E binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0031996	thioesterase binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0032052	bile acid binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0033204	ribonuclease P RNA binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0035256	G protein-coupled glutamate receptor binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0042166	acetylcholine binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0042975	peroxisome proliferator activated receptor binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0043208	glycosphingolipid binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0043295	glutathione binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0050308	sugar-phosphatase activity	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0050815	phosphoserine residue binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0051880	G-quadruplex DNA binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0070513	death domain binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0098505	G-rich strand telomeric DNA binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0099122	RNA polymerase II C-terminal domain binding	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0140940	histone H2A methyltransferase activity	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:1990259	histone H2AQ104 methyltransferase activity	1/715	10/18639	0.1	2.60685314685315	0.323790249558149	0.719314487389496
GO:0038064	collagen receptor activity	3/715	53/18639	0.0566037735849057	1.47557725293574	0.332423417694477	0.719314487389496
GO:0051536	iron-sulfur cluster binding	4/715	76/18639	0.0526315789473684	1.37202797202797	0.333359157136035	0.719314487389496
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/715	31/18639	0.0645161290322581	1.68184073990526	0.33481549761218	0.719314487389496
GO:0140457	protein demethylase activity	2/715	31/18639	0.0645161290322581	1.68184073990526	0.33481549761218	0.719314487389496
GO:0003779	actin binding	19/715	443/18639	0.0428893905191874	1.11806342641557	0.341474800925191	0.719314487389496
GO:0051540	metal cluster binding	4/715	77/18639	0.051948051948052	1.3542094269367	0.342134151170412	0.719314487389496
GO:0003925	G protein activity	3/715	54/18639	0.0555555555555556	1.44825174825175	0.343019773258619	0.719314487389496
GO:0046982	protein heterodimerization activity	16/715	369/18639	0.043360433604336	1.1303428279038	0.343466964995565	0.719314487389496
GO:0140030	modification-dependent protein binding	8/715	173/18639	0.046242774566474	1.20548122397833	0.345913661951621	0.719314487389496
GO:0008378	galactosyltransferase activity	2/715	32/18639	0.0625	1.62928321678322	0.348937889823531	0.719314487389496
GO:0022884	macromolecule transmembrane transporter activity	2/715	32/18639	0.0625	1.62928321678322	0.348937889823531	0.719314487389496
GO:0030515	snoRNA binding	2/715	32/18639	0.0625	1.62928321678322	0.348937889823531	0.719314487389496
GO:0031369	translation initiation factor binding	2/715	32/18639	0.0625	1.62928321678322	0.348937889823531	0.719314487389496
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0008199	ferric iron binding	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0008432	JUN kinase binding	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0008526	phosphatidylinositol transfer activity	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0010854	adenylate cyclase regulator activity	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0015173	aromatic amino acid transmembrane transporter activity	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0015217	ADP transmembrane transporter activity	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0019203	carbohydrate phosphatase activity	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0019864	IgG binding	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0031731	CCR6 chemokine receptor binding	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0032794	GTPase activating protein binding	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0034713	type I transforming growth factor beta receptor binding	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0048185	activin binding	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0048407	platelet-derived growth factor binding	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0097493	structural molecule activity conferring elasticity	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0140031	phosphorylation-dependent protein binding	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0140537	transcription regulator activator activity	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0180030	inositol phosphate kinase activity	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:1900750	oligopeptide binding	1/715	11/18639	0.0909090909090909	2.36986649713922	0.349743868730725	0.719314487389496
GO:0019199	transmembrane receptor protein kinase activity	4/715	78/18639	0.0512820512820513	1.336847767617	0.35091514388809	0.720090578068999
GO:0098632	cell-cell adhesion mediator activity	3/715	55/18639	0.0545454545454545	1.42191989828353	0.35360211613427	0.723966409331339
GO:0019956	chemokine binding	2/715	33/18639	0.0606060606060606	1.57991099809282	0.362957231762754	0.733503463202997
GO:0030296	protein tyrosine kinase activator activity	2/715	33/18639	0.0606060606060606	1.57991099809282	0.362957231762754	0.733503463202997
GO:0030170	pyridoxal phosphate binding	3/715	56/18639	0.0535714285714286	1.39652847152847	0.36416305692433	0.733503463202997
GO:0070279	vitamin B6 binding	3/715	57/18639	0.0526315789473684	1.37202797202797	0.374695518971594	0.733503463202997
GO:0005095	GTPase inhibitor activity	1/715	12/18639	0.0833333333333333	2.17237762237762	0.374702701340643	0.733503463202997
GO:0005527	macrolide binding	1/715	12/18639	0.0833333333333333	2.17237762237762	0.374702701340643	0.733503463202997
GO:0008179	adenylate cyclase binding	1/715	12/18639	0.0833333333333333	2.17237762237762	0.374702701340643	0.733503463202997
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/715	12/18639	0.0833333333333333	2.17237762237762	0.374702701340643	0.733503463202997
GO:0008603	cAMP-dependent protein kinase regulator activity	1/715	12/18639	0.0833333333333333	2.17237762237762	0.374702701340643	0.733503463202997
GO:0010853	cyclase activator activity	1/715	12/18639	0.0833333333333333	2.17237762237762	0.374702701340643	0.733503463202997
GO:0015166	polyol transmembrane transporter activity	1/715	12/18639	0.0833333333333333	2.17237762237762	0.374702701340643	0.733503463202997
GO:0016208	AMP binding	1/715	12/18639	0.0833333333333333	2.17237762237762	0.374702701340643	0.733503463202997
GO:0035497	cAMP response element binding	1/715	12/18639	0.0833333333333333	2.17237762237762	0.374702701340643	0.733503463202997
GO:0036009	protein-glutamine N-methyltransferase activity	1/715	12/18639	0.0833333333333333	2.17237762237762	0.374702701340643	0.733503463202997
GO:0042301	phosphate ion binding	1/715	12/18639	0.0833333333333333	2.17237762237762	0.374702701340643	0.733503463202997
GO:0043047	single-stranded telomeric DNA binding	1/715	12/18639	0.0833333333333333	2.17237762237762	0.374702701340643	0.733503463202997
GO:0070679	inositol 1,4,5 trisphosphate binding	1/715	12/18639	0.0833333333333333	2.17237762237762	0.374702701340643	0.733503463202997
GO:0097677	STAT family protein binding	1/715	12/18639	0.0833333333333333	2.17237762237762	0.374702701340643	0.733503463202997
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/715	12/18639	0.0833333333333333	2.17237762237762	0.374702701340643	0.733503463202997
GO:0008376	acetylgalactosaminyltransferase activity	2/715	34/18639	0.0588235294117647	1.53344302756067	0.376860654743767	0.733503463202997
GO:0015035	protein-disulfide reductase activity	2/715	34/18639	0.0588235294117647	1.53344302756067	0.376860654743767	0.733503463202997
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	2/715	34/18639	0.0588235294117647	1.53344302756067	0.376860654743767	0.733503463202997
GO:0090482	vitamin transmembrane transporter activity	2/715	34/18639	0.0588235294117647	1.53344302756067	0.376860654743767	0.733503463202997
GO:0005506	iron ion binding	7/715	154/18639	0.0454545454545455	1.18493324856961	0.37844016555763	0.735000492849615
GO:0016298	lipase activity	6/715	130/18639	0.0461538461538462	1.2031629908553	0.381631965377207	0.739615796147706
GO:0008408	3'-5' exonuclease activity	3/715	58/18639	0.0517241379310345	1.34837231733783	0.385192735747088	0.741035403314279
GO:0000175	3'-5'-RNA exonuclease activity	2/715	35/18639	0.0571428571428571	1.48963036963037	0.390636426156133	0.741035403314279
GO:0043015	gamma-tubulin binding	2/715	35/18639	0.0571428571428571	1.48963036963037	0.390636426156133	0.741035403314279
GO:0005179	hormone activity	6/715	132/18639	0.0454545454545455	1.18493324856961	0.395406951781065	0.741035403314279
GO:0004879	nuclear receptor activity	3/715	59/18639	0.0508474576271186	1.32551854924736	0.395648247579985	0.741035403314279
GO:0015459	potassium channel regulator activity	3/715	59/18639	0.0508474576271186	1.32551854924736	0.395648247579985	0.741035403314279
GO:0045309	protein phosphorylated amino acid binding	3/715	59/18639	0.0508474576271186	1.32551854924736	0.395648247579985	0.741035403314279
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/715	13/18639	0.0769230769230769	2.0052716514255	0.39870482559798	0.741035403314279
GO:0004535	poly(A)-specific ribonuclease activity	1/715	13/18639	0.0769230769230769	2.0052716514255	0.39870482559798	0.741035403314279
GO:0005172	vascular endothelial growth factor receptor binding	1/715	13/18639	0.0769230769230769	2.0052716514255	0.39870482559798	0.741035403314279
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/715	13/18639	0.0769230769230769	2.0052716514255	0.39870482559798	0.741035403314279
GO:0031432	titin binding	1/715	13/18639	0.0769230769230769	2.0052716514255	0.39870482559798	0.741035403314279
GO:0045159	myosin II binding	1/715	13/18639	0.0769230769230769	2.0052716514255	0.39870482559798	0.741035403314279
GO:0046974	histone H3K9 methyltransferase activity	1/715	13/18639	0.0769230769230769	2.0052716514255	0.39870482559798	0.741035403314279
GO:0051011	microtubule minus-end binding	1/715	13/18639	0.0769230769230769	2.0052716514255	0.39870482559798	0.741035403314279
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/715	13/18639	0.0769230769230769	2.0052716514255	0.39870482559798	0.741035403314279
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/715	13/18639	0.0769230769230769	2.0052716514255	0.39870482559798	0.741035403314279
GO:0089720	caspase binding	1/715	13/18639	0.0769230769230769	2.0052716514255	0.39870482559798	0.741035403314279
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/715	13/18639	0.0769230769230769	2.0052716514255	0.39870482559798	0.741035403314279
GO:0140666	annealing activity	1/715	13/18639	0.0769230769230769	2.0052716514255	0.39870482559798	0.741035403314279
GO:0000993	RNA polymerase II complex binding	2/715	36/18639	0.0555555555555556	1.44825174825175	0.404273881450144	0.742259940233362
GO:0004033	aldo-keto reductase (NADPH) activity	2/715	36/18639	0.0555555555555556	1.44825174825175	0.404273881450144	0.742259940233362
GO:0044390	ubiquitin-like protein conjugating enzyme binding	2/715	36/18639	0.0555555555555556	1.44825174825175	0.404273881450144	0.742259940233362
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	2/715	36/18639	0.0555555555555556	1.44825174825175	0.404273881450144	0.742259940233362
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	2/715	36/18639	0.0555555555555556	1.44825174825175	0.404273881450144	0.742259940233362
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	2/715	36/18639	0.0555555555555556	1.44825174825175	0.404273881450144	0.742259940233362
GO:0098531	ligand-modulated transcription factor activity	3/715	60/18639	0.05	1.30342657342657	0.406055897798464	0.744025655157994
GO:0004222	metalloendopeptidase activity	5/715	110/18639	0.0454545454545455	1.18493324856961	0.414915883586305	0.75307221607463
GO:0042805	actinin binding	2/715	37/18639	0.0540540540540541	1.40910980910981	0.417763359656509	0.75307221607463
GO:0005161	platelet-derived growth factor receptor binding	1/715	14/18639	0.0714285714285714	1.86203796203796	0.421786864130002	0.75307221607463
GO:0005347	ATP transmembrane transporter activity	1/715	14/18639	0.0714285714285714	1.86203796203796	0.421786864130002	0.75307221607463
GO:0008195	phosphatidate phosphatase activity	1/715	14/18639	0.0714285714285714	1.86203796203796	0.421786864130002	0.75307221607463
GO:0008494	translation activator activity	1/715	14/18639	0.0714285714285714	1.86203796203796	0.421786864130002	0.75307221607463
GO:0019763	immunoglobulin receptor activity	1/715	14/18639	0.0714285714285714	1.86203796203796	0.421786864130002	0.75307221607463
GO:0019992	diacylglycerol binding	1/715	14/18639	0.0714285714285714	1.86203796203796	0.421786864130002	0.75307221607463
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/715	14/18639	0.0714285714285714	1.86203796203796	0.421786864130002	0.75307221607463
GO:0042043	neurexin family protein binding	1/715	14/18639	0.0714285714285714	1.86203796203796	0.421786864130002	0.75307221607463
GO:0044548	S100 protein binding	1/715	14/18639	0.0714285714285714	1.86203796203796	0.421786864130002	0.75307221607463
GO:0046030	inositol trisphosphate phosphatase activity	1/715	14/18639	0.0714285714285714	1.86203796203796	0.421786864130002	0.75307221607463
GO:1901612	cardiolipin binding	1/715	14/18639	0.0714285714285714	1.86203796203796	0.421786864130002	0.75307221607463
GO:0003730	mRNA 3'-UTR binding	11/715	262/18639	0.0419847328244275	1.09448032883147	0.423387228767274	0.754444433186479
GO:0031406	carboxylic acid binding	8/715	187/18639	0.0427807486631016	1.1152312927714	0.427697994623231	0.760278880319421
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	2/715	38/18639	0.0526315789473684	1.37202797202797	0.431096142270155	0.760278880319421
GO:0005507	copper ion binding	3/715	63/18639	0.0476190476190476	1.24135864135864	0.43693456177708	0.760278880319421
GO:0004197	cysteine-type endopeptidase activity	4/715	88/18639	0.0454545454545455	1.18493324856961	0.438106209624167	0.760278880319421
GO:0043177	organic acid binding	8/715	189/18639	0.0423280423280423	1.1034299034299	0.43937741367547	0.760278880319421
GO:0004089	carbonate dehydratase activity	1/715	15/18639	0.0666666666666667	1.7379020979021	0.443984039547293	0.760278880319421
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/715	15/18639	0.0666666666666667	1.7379020979021	0.443984039547293	0.760278880319421
GO:0004953	icosanoid receptor activity	1/715	15/18639	0.0666666666666667	1.7379020979021	0.443984039547293	0.760278880319421
GO:0005041	low-density lipoprotein particle receptor activity	1/715	15/18639	0.0666666666666667	1.7379020979021	0.443984039547293	0.760278880319421
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/715	15/18639	0.0666666666666667	1.7379020979021	0.443984039547293	0.760278880319421
GO:0015929	hexosaminidase activity	1/715	15/18639	0.0666666666666667	1.7379020979021	0.443984039547293	0.760278880319421
GO:0016846	carbon-sulfur lyase activity	1/715	15/18639	0.0666666666666667	1.7379020979021	0.443984039547293	0.760278880319421
GO:0017081	chloride channel regulator activity	1/715	15/18639	0.0666666666666667	1.7379020979021	0.443984039547293	0.760278880319421
GO:0031005	filamin binding	1/715	15/18639	0.0666666666666667	1.7379020979021	0.443984039547293	0.760278880319421
GO:0033130	acetylcholine receptor binding	1/715	15/18639	0.0666666666666667	1.7379020979021	0.443984039547293	0.760278880319421
GO:0047372	monoacylglycerol lipase activity	1/715	15/18639	0.0666666666666667	1.7379020979021	0.443984039547293	0.760278880319421
GO:0120283	protein serine/threonine kinase binding	1/715	15/18639	0.0666666666666667	1.7379020979021	0.443984039547293	0.760278880319421
GO:0141050	histone H3K deacetylase activity	1/715	15/18639	0.0666666666666667	1.7379020979021	0.443984039547293	0.760278880319421
GO:0141051	histone H4K deacetylase activity	1/715	15/18639	0.0666666666666667	1.7379020979021	0.443984039547293	0.760278880319421
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	2/715	39/18639	0.0512820512820513	1.336847767617	0.444264395335494	0.760278880319421
GO:0016776	phosphotransferase activity, phosphate group as acceptor	2/715	39/18639	0.0512820512820513	1.336847767617	0.444264395335494	0.760278880319421
GO:0019902	phosphatase binding	8/715	190/18639	0.0421052631578947	1.09762237762238	0.445206060245136	0.760455549232275
GO:0015036	disulfide oxidoreductase activity	2/715	40/18639	0.05	1.30342657342657	0.457261114578008	0.778574585002653
GO:0020037	heme binding	6/715	142/18639	0.0422535211267606	1.10148724514922	0.463781120108468	0.778574585002653
GO:0003688	DNA replication origin binding	1/715	16/18639	0.0625	1.62928321678322	0.465330227891564	0.778574585002653
GO:0005149	interleukin-1 receptor binding	1/715	16/18639	0.0625	1.62928321678322	0.465330227891564	0.778574585002653
GO:0005159	insulin-like growth factor receptor binding	1/715	16/18639	0.0625	1.62928321678322	0.465330227891564	0.778574585002653
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/715	16/18639	0.0625	1.62928321678322	0.465330227891564	0.778574585002653
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/715	16/18639	0.0625	1.62928321678322	0.465330227891564	0.778574585002653
GO:0022858	alanine transmembrane transporter activity	1/715	16/18639	0.0625	1.62928321678322	0.465330227891564	0.778574585002653
GO:0055102	lipase inhibitor activity	1/715	16/18639	0.0625	1.62928321678322	0.465330227891564	0.778574585002653
GO:0070411	I-SMAD binding	1/715	16/18639	0.0625	1.62928321678322	0.465330227891564	0.778574585002653
GO:0097027	ubiquitin-protein transferase activator activity	1/715	16/18639	0.0625	1.62928321678322	0.465330227891564	0.778574585002653
GO:0016247	channel regulator activity	7/715	168/18639	0.0416666666666667	1.08618881118881	0.466391462988985	0.778574585002653
GO:0015175	neutral L-amino acid transmembrane transporter activity	2/715	41/18639	0.0487804878048781	1.27163568139178	0.47008007343417	0.778574585002653
GO:0042169	SH2 domain binding	2/715	41/18639	0.0487804878048781	1.27163568139178	0.47008007343417	0.778574585002653
GO:0140318	protein transporter activity	2/715	41/18639	0.0487804878048781	1.27163568139178	0.47008007343417	0.778574585002653
GO:0042393	histone binding	10/715	247/18639	0.0404858299595142	1.05540613232921	0.476516459326518	0.778574585002653
GO:0008173	RNA methyltransferase activity	3/715	67/18639	0.0447761194029851	1.16724767769544	0.477113571097869	0.778574585002653
GO:0141108	transporter regulator activity	7/715	170/18639	0.0411764705882353	1.07341011929247	0.478777562577612	0.778574585002653
GO:0051219	phosphoprotein binding	4/715	93/18639	0.043010752688172	1.12122715993684	0.480520928737757	0.778574585002653
GO:0008307	structural constituent of muscle	2/715	42/18639	0.0476190476190476	1.24135864135864	0.482715773838569	0.778574585002653
GO:0016859	cis-trans isomerase activity	2/715	42/18639	0.0476190476190476	1.24135864135864	0.482715773838569	0.778574585002653
GO:0031492	nucleosomal DNA binding	2/715	42/18639	0.0476190476190476	1.24135864135864	0.482715773838569	0.778574585002653
GO:0004550	nucleoside diphosphate kinase activity	1/715	17/18639	0.0588235294117647	1.53344302756067	0.485858010045757	0.778574585002653
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/715	17/18639	0.0588235294117647	1.53344302756067	0.485858010045757	0.778574585002653
GO:0008484	sulfuric ester hydrolase activity	1/715	17/18639	0.0588235294117647	1.53344302756067	0.485858010045757	0.778574585002653
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/715	17/18639	0.0588235294117647	1.53344302756067	0.485858010045757	0.778574585002653
GO:0016018	cyclosporin A binding	1/715	17/18639	0.0588235294117647	1.53344302756067	0.485858010045757	0.778574585002653
GO:0019198	transmembrane receptor protein phosphatase activity	1/715	17/18639	0.0588235294117647	1.53344302756067	0.485858010045757	0.778574585002653
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/715	17/18639	0.0588235294117647	1.53344302756067	0.485858010045757	0.778574585002653
GO:0030548	acetylcholine receptor regulator activity	1/715	17/18639	0.0588235294117647	1.53344302756067	0.485858010045757	0.778574585002653
GO:0032183	SUMO binding	1/715	17/18639	0.0588235294117647	1.53344302756067	0.485858010045757	0.778574585002653
GO:0038191	neuropilin binding	1/715	17/18639	0.0588235294117647	1.53344302756067	0.485858010045757	0.778574585002653
GO:0045236	CXCR chemokine receptor binding	1/715	17/18639	0.0588235294117647	1.53344302756067	0.485858010045757	0.778574585002653
GO:0046965	nuclear retinoid X receptor binding	1/715	17/18639	0.0588235294117647	1.53344302756067	0.485858010045757	0.778574585002653
GO:0070403	NAD+ binding	1/715	17/18639	0.0588235294117647	1.53344302756067	0.485858010045757	0.778574585002653
GO:1901681	sulfur compound binding	11/715	275/18639	0.04	1.04274125874126	0.487124684564203	0.779227670017164
GO:0008200	ion channel inhibitor activity	2/715	43/18639	0.0465116279069767	1.21248983574565	0.495163399633651	0.785373424289514
GO:0008375	acetylglucosaminyltransferase activity	2/715	43/18639	0.0465116279069767	1.21248983574565	0.495163399633651	0.785373424289514
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/715	43/18639	0.0465116279069767	1.21248983574565	0.495163399633651	0.785373424289514
GO:0004867	serine-type endopeptidase inhibitor activity	4/715	95/18639	0.0421052631578947	1.09762237762238	0.497138000361641	0.785373424289514
GO:0000900	mRNA regulatory element binding translation repressor activity	1/715	18/18639	0.0555555555555556	1.44825174825175	0.505598721184049	0.785373424289514
GO:0008409	5'-3' exonuclease activity	1/715	18/18639	0.0555555555555556	1.44825174825175	0.505598721184049	0.785373424289514
GO:0008525	phosphatidylcholine transporter activity	1/715	18/18639	0.0555555555555556	1.44825174825175	0.505598721184049	0.785373424289514
GO:0015172	acidic amino acid transmembrane transporter activity	1/715	18/18639	0.0555555555555556	1.44825174825175	0.505598721184049	0.785373424289514
GO:0017075	syntaxin-1 binding	1/715	18/18639	0.0555555555555556	1.44825174825175	0.505598721184049	0.785373424289514
GO:0017128	phospholipid scramblase activity	1/715	18/18639	0.0555555555555556	1.44825174825175	0.505598721184049	0.785373424289514
GO:0030228	lipoprotein particle receptor activity	1/715	18/18639	0.0555555555555556	1.44825174825175	0.505598721184049	0.785373424289514
GO:0034185	apolipoprotein binding	1/715	18/18639	0.0555555555555556	1.44825174825175	0.505598721184049	0.785373424289514
GO:0070628	proteasome binding	1/715	18/18639	0.0555555555555556	1.44825174825175	0.505598721184049	0.785373424289514
GO:0098641	cadherin binding involved in cell-cell adhesion	1/715	18/18639	0.0555555555555556	1.44825174825175	0.505598721184049	0.785373424289514
GO:0099602	neurotransmitter receptor regulator activity	1/715	18/18639	0.0555555555555556	1.44825174825175	0.505598721184049	0.785373424289514
GO:1990381	ubiquitin-specific protease binding	1/715	18/18639	0.0555555555555556	1.44825174825175	0.505598721184049	0.785373424289514
GO:0016248	channel inhibitor activity	2/715	44/18639	0.0454545454545455	1.18493324856961	0.50741877247371	0.785373424289514
GO:0019205	nucleobase-containing compound kinase activity	2/715	44/18639	0.0454545454545455	1.18493324856961	0.50741877247371	0.785373424289514
GO:0043014	alpha-tubulin binding	2/715	44/18639	0.0454545454545455	1.18493324856961	0.50741877247371	0.785373424289514
GO:0141110	transporter inhibitor activity	2/715	45/18639	0.0444444444444444	1.1586013986014	0.519478310100781	0.798315983206526
GO:0000287	magnesium ion binding	9/715	230/18639	0.0391304347826087	1.02007297050775	0.523624115917555	0.798315983206526
GO:0005085	guanyl-nucleotide exchange factor activity	9/715	230/18639	0.0391304347826087	1.02007297050775	0.523624115917555	0.798315983206526
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/715	19/18639	0.0526315789473684	1.37202797202797	0.524582498336372	0.798315983206526
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/715	19/18639	0.0526315789473684	1.37202797202797	0.524582498336372	0.798315983206526
GO:0008301	DNA binding, bending	1/715	19/18639	0.0526315789473684	1.37202797202797	0.524582498336372	0.798315983206526
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/715	19/18639	0.0526315789473684	1.37202797202797	0.524582498336372	0.798315983206526
GO:0046624	sphingolipid transporter activity	1/715	19/18639	0.0526315789473684	1.37202797202797	0.524582498336372	0.798315983206526
GO:0050145	nucleoside monophosphate kinase activity	1/715	19/18639	0.0526315789473684	1.37202797202797	0.524582498336372	0.798315983206526
GO:0140036	ubiquitin-modified protein reader activity	1/715	19/18639	0.0526315789473684	1.37202797202797	0.524582498336372	0.798315983206526
GO:0046906	tetrapyrrole binding	6/715	152/18639	0.0394736842105263	1.02902097902098	0.530001236498953	0.805211258801592
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/715	46/18639	0.0434782608695652	1.13341441167528	0.531338986875711	0.805893747652625
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/715	20/18639	0.05	1.30342657342657	0.542838326139245	0.812705371094152
GO:0010851	cyclase regulator activity	1/715	20/18639	0.05	1.30342657342657	0.542838326139245	0.812705371094152
GO:0015464	acetylcholine receptor activity	1/715	20/18639	0.05	1.30342657342657	0.542838326139245	0.812705371094152
GO:0016505	peptidase activator activity involved in apoptotic process	1/715	20/18639	0.05	1.30342657342657	0.542838326139245	0.812705371094152
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/715	20/18639	0.05	1.30342657342657	0.542838326139245	0.812705371094152
GO:0052745	inositol phosphate phosphatase activity	1/715	20/18639	0.05	1.30342657342657	0.542838326139245	0.812705371094152
GO:0001784	phosphotyrosine residue binding	2/715	47/18639	0.0425531914893617	1.10929921142687	0.542998296453204	0.812705371094152
GO:0140359	ABC-type transporter activity	2/715	47/18639	0.0425531914893617	1.10929921142687	0.542998296453204	0.812705371094152
GO:0048029	monosaccharide binding	3/715	74/18639	0.0405405405405405	1.05683235683236	0.543966343282659	0.812812970934715
GO:0019003	GDP binding	3/715	75/18639	0.04	1.04274125874126	0.553106821997628	0.824550947054705
GO:0038187	pattern recognition receptor activity	2/715	48/18639	0.0416666666666667	1.08618881118881	0.554454216494774	0.824550947054705
GO:0005123	death receptor binding	1/715	21/18639	0.0476190476190476	1.24135864135864	0.560394080841992	0.824550947054705
GO:0008373	sialyltransferase activity	1/715	21/18639	0.0476190476190476	1.24135864135864	0.560394080841992	0.824550947054705
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/715	21/18639	0.0476190476190476	1.24135864135864	0.560394080841992	0.824550947054705
GO:0061891	calcium ion sensor activity	1/715	21/18639	0.0476190476190476	1.24135864135864	0.560394080841992	0.824550947054705
GO:0001222	transcription corepressor binding	2/715	49/18639	0.0408163265306122	1.06402169259312	0.56570517531854	0.824550947054705
GO:0016763	pentosyltransferase activity	2/715	49/18639	0.0408163265306122	1.06402169259312	0.56570517531854	0.824550947054705
GO:0016757	glycosyltransferase activity	10/715	267/18639	0.0374531835205993	0.976349493203426	0.576034718441911	0.824550947054705
GO:0015605	organophosphate ester transmembrane transporter activity	2/715	50/18639	0.04	1.04274125874126	0.576750020389512	0.824550947054705
GO:0004407	histone deacetylase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0032931	histone H3K56 acetyltransferase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0033558	protein lysine deacetylase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0034062	5'-3' RNA polymerase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0043992	histone H3K9 acetyltransferase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0043993	histone H3K18 acetyltransferase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0043994	histone H3K23 acetyltransferase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0043999	histone H2AK5 acetyltransferase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0044012	histone H2AK9 acetyltransferase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0044014	histone H2BK5 acetyltransferase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0044015	histone H2BK12 acetyltransferase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0044016	histone H3K4 acetyltransferase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0044017	histone H3K27 acetyltransferase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0044018	histone H3K36 acetyltransferase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0046972	histone H4K16 acetyltransferase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0097747	RNA polymerase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0140035	ubiquitin-like protein reader activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0140908	histone H3K122 acetyltransferase activity	1/715	22/18639	0.0454545454545455	1.18493324856961	0.577276572634771	0.824550947054705
GO:0008013	beta-catenin binding	4/715	106/18639	0.0377358490566038	0.983718168623829	0.583942292641961	0.832017015194192
GO:0004866	endopeptidase inhibitor activity	6/715	161/18639	0.0372670807453416	0.971498067150241	0.586536607197917	0.832017015194192
GO:0016597	amino acid binding	2/715	51/18639	0.0392156862745098	1.02229535170712	0.587587988558569	0.832017015194192
GO:0016835	carbon-oxygen lyase activity	3/715	79/18639	0.0379746835443038	0.989944232982208	0.588552975128341	0.832017015194192
GO:0033293	monocarboxylic acid binding	3/715	79/18639	0.0379746835443038	0.989944232982208	0.588552975128341	0.832017015194192
GO:0000295	adenine nucleotide transmembrane transporter activity	1/715	23/18639	0.0434782608695652	1.13341441167528	0.59351158636234	0.832017015194192
GO:0003887	DNA-directed DNA polymerase activity	1/715	23/18639	0.0434782608695652	1.13341441167528	0.59351158636234	0.832017015194192
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/715	23/18639	0.0434782608695652	1.13341441167528	0.59351158636234	0.832017015194192
GO:0004602	glutathione peroxidase activity	1/715	23/18639	0.0434782608695652	1.13341441167528	0.59351158636234	0.832017015194192
GO:0016493	C-C chemokine receptor activity	1/715	23/18639	0.0434782608695652	1.13341441167528	0.59351158636234	0.832017015194192
GO:0044013	histone H2B acetyltransferase activity	1/715	23/18639	0.0434782608695652	1.13341441167528	0.59351158636234	0.832017015194192
GO:0070577	lysine-acetylated histone binding	1/715	23/18639	0.0434782608695652	1.13341441167528	0.59351158636234	0.832017015194192
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	2/715	52/18639	0.0384615384615385	1.00263582571275	0.59821867796261	0.834332239351627
GO:0044325	transmembrane transporter binding	5/715	136/18639	0.0367647058823529	0.958401892225422	0.60145584440839	0.834332239351627
GO:0004864	protein phosphatase inhibitor activity	2/715	53/18639	0.0377358490566038	0.983718168623829	0.608642021502537	0.834332239351627
GO:0051018	protein kinase A binding	2/715	53/18639	0.0377358490566038	0.983718168623829	0.608642021502537	0.834332239351627
GO:0005315	phosphate transmembrane transporter activity	1/715	24/18639	0.0416666666666667	1.08618881118881	0.609123920685015	0.834332239351627
GO:0015149	hexose transmembrane transporter activity	1/715	24/18639	0.0416666666666667	1.08618881118881	0.609123920685015	0.834332239351627
GO:0015295	solute:proton symporter activity	1/715	24/18639	0.0416666666666667	1.08618881118881	0.609123920685015	0.834332239351627
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/715	24/18639	0.0416666666666667	1.08618881118881	0.609123920685015	0.834332239351627
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/715	24/18639	0.0416666666666667	1.08618881118881	0.609123920685015	0.834332239351627
GO:0043998	histone H2A acetyltransferase activity	1/715	24/18639	0.0416666666666667	1.08618881118881	0.609123920685015	0.834332239351627
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/715	24/18639	0.0416666666666667	1.08618881118881	0.609123920685015	0.834332239351627
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/715	24/18639	0.0416666666666667	1.08618881118881	0.609123920685015	0.834332239351627
GO:0050699	WW domain binding	1/715	24/18639	0.0416666666666667	1.08618881118881	0.609123920685015	0.834332239351627
GO:0055056	D-glucose transmembrane transporter activity	1/715	24/18639	0.0416666666666667	1.08618881118881	0.609123920685015	0.834332239351627
GO:0140033	acetylation-dependent protein binding	1/715	24/18639	0.0416666666666667	1.08618881118881	0.609123920685015	0.834332239351627
GO:0033218	amide binding	9/715	247/18639	0.0364372469635627	0.949865519096288	0.609881228985809	0.834332239351627
GO:0051287	NAD binding	2/715	54/18639	0.037037037037037	0.965501165501165	0.61885826181961	0.843655208869778
GO:0000030	mannosyltransferase activity	1/715	25/18639	0.04	1.04274125874126	0.624137425745999	0.843655208869778
GO:0003707	nuclear steroid receptor activity	1/715	25/18639	0.04	1.04274125874126	0.624137425745999	0.843655208869778
GO:0005537	D-mannose binding	1/715	25/18639	0.04	1.04274125874126	0.624137425745999	0.843655208869778
GO:0008139	nuclear localization sequence binding	1/715	25/18639	0.04	1.04274125874126	0.624137425745999	0.843655208869778
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/715	25/18639	0.04	1.04274125874126	0.624137425745999	0.843655208869778
GO:0017025	TBP-class protein binding	1/715	25/18639	0.04	1.04274125874126	0.624137425745999	0.843655208869778
GO:0120020	cholesterol transfer activity	1/715	25/18639	0.04	1.04274125874126	0.624137425745999	0.843655208869778
GO:0030414	peptidase inhibitor activity	6/715	169/18639	0.0355029585798817	0.925509992965614	0.633690367542375	0.845657420875907
GO:0016758	hexosyltransferase activity	7/715	197/18639	0.0355329949238579	0.926292996343758	0.634830604444232	0.845657420875907
GO:0001637	G protein-coupled chemoattractant receptor activity	1/715	26/18639	0.0384615384615385	1.00263582571275	0.638575039401936	0.845657420875907
GO:0004950	chemokine receptor activity	1/715	26/18639	0.0384615384615385	1.00263582571275	0.638575039401936	0.845657420875907
GO:0005160	transforming growth factor beta receptor binding	1/715	26/18639	0.0384615384615385	1.00263582571275	0.638575039401936	0.845657420875907
GO:0015145	monosaccharide transmembrane transporter activity	1/715	26/18639	0.0384615384615385	1.00263582571275	0.638575039401936	0.845657420875907
GO:0015216	purine nucleotide transmembrane transporter activity	1/715	26/18639	0.0384615384615385	1.00263582571275	0.638575039401936	0.845657420875907
GO:0019865	immunoglobulin binding	1/715	26/18639	0.0384615384615385	1.00263582571275	0.638575039401936	0.845657420875907
GO:0050681	nuclear androgen receptor binding	1/715	26/18639	0.0384615384615385	1.00263582571275	0.638575039401936	0.845657420875907
GO:0050750	low-density lipoprotein particle receptor binding	1/715	26/18639	0.0384615384615385	1.00263582571275	0.638575039401936	0.845657420875907
GO:0052742	phosphatidylinositol kinase activity	1/715	26/18639	0.0384615384615385	1.00263582571275	0.638575039401936	0.845657420875907
GO:0070006	metalloaminopeptidase activity	1/715	26/18639	0.0384615384615385	1.00263582571275	0.638575039401936	0.845657420875907
GO:0120014	phospholipid transfer activity	1/715	26/18639	0.0384615384615385	1.00263582571275	0.638575039401936	0.845657420875907
GO:0019212	phosphatase inhibitor activity	2/715	56/18639	0.0357142857142857	0.931018981018981	0.638671811797129	0.845657420875907
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	3/715	86/18639	0.0348837209302326	0.909367376809237	0.646074263116672	0.854211890155717
GO:0015932	nucleobase-containing compound transmembrane transporter activity	2/715	57/18639	0.0350877192982456	0.914685314685315	0.648270949718057	0.855868633761686
GO:0004683	calcium/calmodulin-dependent protein kinase activity	1/715	27/18639	0.037037037037037	0.965501165501165	0.652458822071447	0.857652393650439
GO:0008266	poly(U) RNA binding	1/715	27/18639	0.037037037037037	0.965501165501165	0.652458822071447	0.857652393650439
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	1/715	27/18639	0.037037037037037	0.965501165501165	0.652458822071447	0.857652393650439
GO:0008194	UDP-glycosyltransferase activity	5/715	145/18639	0.0344827586206897	0.898914878225223	0.657714530740012	0.863309810971332
GO:0019789	SUMO transferase activity	1/715	28/18639	0.0357142857142857	0.931018981018981	0.665809990254282	0.868905987281487
GO:0036408	histone H3K14 acetyltransferase activity	1/715	28/18639	0.0357142857142857	0.931018981018981	0.665809990254282	0.868905987281487
GO:0051119	sugar transmembrane transporter activity	1/715	28/18639	0.0357142857142857	0.931018981018981	0.665809990254282	0.868905987281487
GO:0051393	alpha-actinin binding	1/715	28/18639	0.0357142857142857	0.931018981018981	0.665809990254282	0.868905987281487
GO:0070888	E-box binding	2/715	59/18639	0.0338983050847458	0.883679032831575	0.666860226625338	0.869026186133881
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/715	60/18639	0.0333333333333333	0.868951048951049	0.675853479343506	0.878080736855859
GO:0003785	actin monomer binding	1/715	29/18639	0.0344827586206897	0.898914878225223	0.678648948771728	0.878080736855859
GO:0010484	histone H3 acetyltransferase activity	1/715	29/18639	0.0344827586206897	0.898914878225223	0.678648948771728	0.878080736855859
GO:0035250	UDP-galactosyltransferase activity	1/715	29/18639	0.0344827586206897	0.898914878225223	0.678648948771728	0.878080736855859
GO:0106222	lncRNA binding	1/715	29/18639	0.0344827586206897	0.898914878225223	0.678648948771728	0.878080736855859
GO:0022804	active transmembrane transporter activity	16/715	457/18639	0.0350109409190372	0.912683815090817	0.68191904720319	0.881054951300988
GO:0019842	vitamin binding	5/715	150/18639	0.0333333333333333	0.868951048951049	0.686668033952531	0.885215758265175
GO:0031210	phosphatidylcholine binding	1/715	30/18639	0.0333333333333333	0.868951048951049	0.690995321777006	0.885215758265175
GO:0031624	ubiquitin conjugating enzyme binding	1/715	30/18639	0.0333333333333333	0.868951048951049	0.690995321777006	0.885215758265175
GO:0043995	histone H4K5 acetyltransferase activity	1/715	30/18639	0.0333333333333333	0.868951048951049	0.690995321777006	0.885215758265175
GO:0043996	histone H4K8 acetyltransferase activity	1/715	30/18639	0.0333333333333333	0.868951048951049	0.690995321777006	0.885215758265175
GO:0043997	histone H4K12 acetyltransferase activity	1/715	30/18639	0.0333333333333333	0.868951048951049	0.690995321777006	0.885215758265175
GO:0004175	endopeptidase activity	14/715	405/18639	0.0345679012345679	0.901134421134421	0.69295956946799	0.885597741821049
GO:0015179	L-amino acid transmembrane transporter activity	2/715	62/18639	0.032258064516129	0.840920369952628	0.693246302858815	0.885597741821049
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	6/715	181/18639	0.0331491712707182	0.864150214426457	0.69814535525783	0.889123096516495
GO:0005452	solute:inorganic anion antiporter activity	1/715	31/18639	0.032258064516129	0.840920369952628	0.7028679825825	0.889123096516495
GO:0008327	methyl-CpG binding	1/715	31/18639	0.032258064516129	0.840920369952628	0.7028679825825	0.889123096516495
GO:0017147	Wnt-protein binding	1/715	31/18639	0.032258064516129	0.840920369952628	0.7028679825825	0.889123096516495
GO:0070273	phosphatidylinositol-4-phosphate binding	1/715	31/18639	0.032258064516129	0.840920369952628	0.7028679825825	0.889123096516495
GO:0070325	lipoprotein particle receptor binding	1/715	31/18639	0.032258064516129	0.840920369952628	0.7028679825825	0.889123096516495
GO:0072349	modified amino acid transmembrane transporter activity	1/715	31/18639	0.032258064516129	0.840920369952628	0.7028679825825	0.889123096516495
GO:0008237	metallopeptidase activity	6/715	184/18639	0.0326086956521739	0.850060808756461	0.713012391571382	0.898552801235047
GO:0015106	bicarbonate transmembrane transporter activity	1/715	32/18639	0.03125	0.814641608391608	0.714285082348918	0.898552801235047
GO:0043425	bHLH transcription factor binding	1/715	32/18639	0.03125	0.814641608391608	0.714285082348918	0.898552801235047
GO:0120015	sterol transfer activity	1/715	32/18639	0.03125	0.814641608391608	0.714285082348918	0.898552801235047
GO:1901981	phosphatidylinositol phosphate binding	6/715	185/18639	0.0324324324324324	0.845465885465885	0.717854970333787	0.901792878244799
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/715	33/18639	0.0303030303030303	0.789955499046408	0.725264077679736	0.909840274488963
GO:0042626	ATPase-coupled transmembrane transporter activity	3/715	98/18639	0.0306122448979592	0.798016269444841	0.730880399472681	0.91423333389934
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	2/715	67/18639	0.0298507462686567	0.778165118463626	0.733366535406032	0.91423333389934
GO:0042054	histone methyltransferase activity	2/715	67/18639	0.0298507462686567	0.778165118463626	0.733366535406032	0.91423333389934
GO:0035591	signaling adaptor activity	4/715	129/18639	0.0310077519379845	0.808326557163766	0.734085228774471	0.91423333389934
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/715	34/18639	0.0294117647058824	0.766721513780337	0.735821757162644	0.91423333389934
GO:0051427	hormone receptor binding	1/715	34/18639	0.0294117647058824	0.766721513780337	0.735821757162644	0.91423333389934
GO:0052866	phosphatidylinositol phosphate phosphatase activity	1/715	34/18639	0.0294117647058824	0.766721513780337	0.735821757162644	0.91423333389934
GO:0099106	ion channel regulator activity	5/715	160/18639	0.03125	0.814641608391608	0.739453288413036	0.916693219605225
GO:0005548	phospholipid transporter activity	2/715	68/18639	0.0294117647058824	0.766721513780337	0.740833660386582	0.916693219605225
GO:0140223	general transcription initiation factor activity	2/715	68/18639	0.0294117647058824	0.766721513780337	0.740833660386582	0.916693219605225
GO:0010485	histone H4 acetyltransferase activity	1/715	35/18639	0.0285714285714286	0.744815184815185	0.745974266898129	0.918044314893627
GO:0034061	DNA polymerase activity	1/715	35/18639	0.0285714285714286	0.744815184815185	0.745974266898129	0.918044314893627
GO:0061631	ubiquitin conjugating enzyme activity	1/715	35/18639	0.0285714285714286	0.744815184815185	0.745974266898129	0.918044314893627
GO:0140566	histone reader activity	1/715	35/18639	0.0285714285714286	0.744815184815185	0.745974266898129	0.918044314893627
GO:0030246	carbohydrate binding	9/715	280/18639	0.0321428571428571	0.837917082917083	0.751260311949096	0.923296887449635
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/715	36/18639	0.0277777777777778	0.724125874125874	0.755737135053786	0.926288623640249
GO:0055106	ubiquitin-protein transferase regulator activity	1/715	36/18639	0.0277777777777778	0.724125874125874	0.755737135053786	0.926288623640249
GO:0019213	deacetylase activity	1/715	37/18639	0.027027027027027	0.704554904554905	0.765125295481488	0.93400894078292
GO:0022829	wide pore channel activity	1/715	37/18639	0.027027027027027	0.704554904554905	0.765125295481488	0.93400894078292
GO:0030280	structural constituent of skin epidermis	1/715	37/18639	0.027027027027027	0.704554904554905	0.765125295481488	0.93400894078292
GO:0051020	GTPase binding	10/715	315/18639	0.0317460317460317	0.827572427572428	0.772225813910871	0.939969037701289
GO:0000146	microfilament motor activity	1/715	38/18639	0.0263157894736842	0.686013986013986	0.774153110433146	0.939969037701289
GO:0005109	frizzled binding	1/715	38/18639	0.0263157894736842	0.686013986013986	0.774153110433146	0.939969037701289
GO:0042887	amide transmembrane transporter activity	1/715	38/18639	0.0263157894736842	0.686013986013986	0.774153110433146	0.939969037701289
GO:0003678	DNA helicase activity	2/715	74/18639	0.027027027027027	0.704554904554905	0.781964923006918	0.946705091864244
GO:0000217	DNA secondary structure binding	1/715	39/18639	0.0256410256410256	0.668423883808499	0.7828343924094	0.946705091864244
GO:0140101	catalytic activity, acting on a tRNA	4/715	139/18639	0.0287769784172662	0.750173567439755	0.785147224963731	0.946705091864244
GO:0004713	protein tyrosine kinase activity	4/715	140/18639	0.0285714285714286	0.744815184815185	0.78979570302555	0.946705091864244
GO:0004177	aminopeptidase activity	1/715	40/18639	0.025	0.651713286713287	0.791182425174307	0.946705091864244
GO:0015144	carbohydrate transmembrane transporter activity	1/715	40/18639	0.025	0.651713286713287	0.791182425174307	0.946705091864244
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/715	40/18639	0.025	0.651713286713287	0.791182425174307	0.946705091864244
GO:0030331	nuclear estrogen receptor binding	1/715	40/18639	0.025	0.651713286713287	0.791182425174307	0.946705091864244
GO:0050997	quaternary ammonium group binding	1/715	40/18639	0.025	0.651713286713287	0.791182425174307	0.946705091864244
GO:0061791	GTPase motor activity	1/715	40/18639	0.025	0.651713286713287	0.791182425174307	0.946705091864244
GO:1990606	membrane scission GTPase motor activity	1/715	40/18639	0.025	0.651713286713287	0.791182425174307	0.946705091864244
GO:0017022	myosin binding	2/715	76/18639	0.0263157894736842	0.686013986013986	0.794345750128651	0.949237938559534
GO:0001727	lipid kinase activity	1/715	41/18639	0.024390243902439	0.63581784069589	0.799209983967811	0.951290623961686
GO:0017080	sodium channel regulator activity	1/715	41/18639	0.024390243902439	0.63581784069589	0.799209983967811	0.951290623961686
GO:0061650	ubiquitin-like protein conjugating enzyme activity	1/715	41/18639	0.024390243902439	0.63581784069589	0.799209983967811	0.951290623961686
GO:1902936	phosphatidylinositol bisphosphate binding	3/715	111/18639	0.027027027027027	0.704554904554905	0.803809500947929	0.955511425111104
GO:0019894	kinesin binding	1/715	42/18639	0.0238095238095238	0.620679320679321	0.806929354946573	0.956712320178486
GO:0048487	beta-tubulin binding	1/715	42/18639	0.0238095238095238	0.620679320679321	0.806929354946573	0.956712320178486
GO:0005516	calmodulin binding	6/715	207/18639	0.0289855072463768	0.755609607783521	0.810153905065393	0.959281451559153
GO:0015293	symporter activity	4/715	146/18639	0.0273972602739726	0.714206341603602	0.816015293607386	0.964962022557887
GO:0000049	tRNA binding	2/715	80/18639	0.025	0.651713286713287	0.817254913710595	0.965169540020195
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/715	44/18639	0.0227272727272727	0.592466624284806	0.821490344147918	0.966471756381323
GO:0015101	organic cation transmembrane transporter activity	2/715	81/18639	0.0246913580246914	0.643667443667444	0.822613665174969	0.966471756381323
GO:0035401	histone H3Y41 kinase activity	3/715	115/18639	0.0260869565217391	0.680048647005169	0.822619841153673	0.966471756381323
GO:0140801	histone H2AXY142 kinase activity	3/715	115/18639	0.0260869565217391	0.680048647005169	0.822619841153673	0.966471756381323
GO:0015294	solute:monoatomic cation symporter activity	3/715	116/18639	0.0258620689655172	0.674186158668917	0.827075160813815	0.969441688244453
GO:0051539	4 iron, 4 sulfur cluster binding	1/715	45/18639	0.0222222222222222	0.579300699300699	0.828354254012625	0.969441688244453
GO:0140303	intramembrane lipid transporter activity	1/715	45/18639	0.0222222222222222	0.579300699300699	0.828354254012625	0.969441688244453
GO:1990782	protein tyrosine kinase binding	3/715	117/18639	0.0256410256410256	0.668423883808499	0.831434382787325	0.969767775721713
GO:0001540	amyloid-beta binding	2/715	83/18639	0.0240963855421687	0.628157384783891	0.832909699324382	0.969767775721713
GO:0005254	chloride channel activity	2/715	83/18639	0.0240963855421687	0.628157384783891	0.832909699324382	0.969767775721713
GO:0030165	PDZ domain binding	2/715	83/18639	0.0240963855421687	0.628157384783891	0.832909699324382	0.969767775721713
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/715	46/18639	0.0217391304347826	0.566707205837641	0.834954593282334	0.970902328342407
GO:0016741	transferase activity, transferring one-carbon groups	6/715	215/18639	0.027906976744186	0.72749390144739	0.837211206208668	0.972051506567421
GO:0005504	fatty acid binding	1/715	47/18639	0.0212765957446809	0.554649605713435	0.841301469300359	0.972051506567421
GO:0061749	forked DNA-dependent helicase activity	1/715	47/18639	0.0212765957446809	0.554649605713435	0.841301469300359	0.972051506567421
GO:0140938	histone H3 methyltransferase activity	1/715	47/18639	0.0212765957446809	0.554649605713435	0.841301469300359	0.972051506567421
GO:1990518	single-stranded 3'-5' DNA helicase activity	1/715	47/18639	0.0212765957446809	0.554649605713435	0.841301469300359	0.972051506567421
GO:0009378	four-way junction helicase activity	1/715	48/18639	0.0208333333333333	0.543094405594406	0.847404602338776	0.972906296609202
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/715	48/18639	0.0208333333333333	0.543094405594406	0.847404602338776	0.972906296609202
GO:0032266	phosphatidylinositol-3-phosphate binding	1/715	48/18639	0.0208333333333333	0.543094405594406	0.847404602338776	0.972906296609202
GO:0036121	double-stranded DNA helicase activity	1/715	48/18639	0.0208333333333333	0.543094405594406	0.847404602338776	0.972906296609202
GO:0043138	3'-5' DNA helicase activity	1/715	48/18639	0.0208333333333333	0.543094405594406	0.847404602338776	0.972906296609202
GO:0008234	cysteine-type peptidase activity	5/715	187/18639	0.0267379679144385	0.697019557982125	0.848798077765379	0.973274154909227
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	3/715	122/18639	0.0245901639344262	0.641029462340938	0.851839121925434	0.975527883316122
GO:0031267	small GTPase binding	8/715	283/18639	0.0282685512367491	0.736919617484989	0.854341947850007	0.977160336317726
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	2/715	91/18639	0.021978021978022	0.572934757550142	0.868899753570091	0.987849568701667
GO:0072341	modified amino acid binding	2/715	91/18639	0.021978021978022	0.572934757550142	0.868899753570091	0.987849568701667
GO:0030159	signaling receptor complex adaptor activity	1/715	52/18639	0.0192307692307692	0.501317912856375	0.869561375969079	0.987849568701667
GO:0052689	carboxylic ester hydrolase activity	2/715	92/18639	0.0217391304347826	0.566707205837641	0.872860734714002	0.987849568701667
GO:0008083	growth factor activity	4/715	162/18639	0.0246913580246914	0.643667443667444	0.873013577920904	0.987849568701667
GO:0005544	calcium-dependent phospholipid binding	1/715	53/18639	0.0188679245283019	0.491859084311914	0.874579055862667	0.987849568701667
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/715	53/18639	0.0188679245283019	0.491859084311914	0.874579055862667	0.987849568701667
GO:0017046	peptide hormone binding	1/715	53/18639	0.0188679245283019	0.491859084311914	0.874579055862667	0.987849568701667
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/715	53/18639	0.0188679245283019	0.491859084311914	0.874579055862667	0.987849568701667
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/715	53/18639	0.0188679245283019	0.491859084311914	0.874579055862667	0.987849568701667
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	1/715	54/18639	0.0185185185185185	0.482750582750583	0.879403976504989	0.990783924767159
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	3/715	130/18639	0.0230769230769231	0.601581495427649	0.880013632911978	0.990783924767159
GO:0042562	hormone binding	2/715	94/18639	0.0212765957446809	0.554649605713435	0.880454072064311	0.990783924767159
GO:0008276	protein methyltransferase activity	2/715	95/18639	0.0210526315789474	0.548811188811189	0.884091644904114	0.993644512921972
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	4/715	167/18639	0.0239520958083832	0.624395963318119	0.887386376370755	0.996113172485488
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/715	56/18639	0.0178571428571429	0.465509490509491	0.888504836985665	0.996135830835598
GO:0008170	N-methyltransferase activity	2/715	98/18639	0.0204081632653061	0.532010846296561	0.894398447327933	0.999010790485549
GO:0008514	organic anion transmembrane transporter activity	7/715	269/18639	0.0260223048327138	0.678363272415317	0.895049819979617	0.999010790485549
GO:0008168	methyltransferase activity	5/715	204/18639	0.0245098039215686	0.638934594816948	0.895837603639958	0.999010790485549
GO:0017116	single-stranded DNA helicase activity	1/715	58/18639	0.0172413793103448	0.449457439112611	0.896919782700128	0.999010790485549
GO:0016779	nucleotidyltransferase activity	3/715	136/18639	0.0220588235294118	0.575041135335253	0.897912429087866	0.999010790485549
GO:0001786	phosphatidylserine binding	1/715	59/18639	0.0169491525423729	0.441839516415788	0.900886326770383	0.999010790485549
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/715	60/18639	0.0166666666666667	0.434475524475524	0.904700442828466	0.999010790485549
GO:0140767	enzyme-substrate adaptor activity	3/715	139/18639	0.0215827338129496	0.562630175579816	0.905929309435164	0.999010790485549
GO:0015171	amino acid transmembrane transporter activity	2/715	102/18639	0.0196078431372549	0.511147675853558	0.906817994287367	0.999010790485549
GO:0004674	protein serine/threonine kinase activity	12/715	433/18639	0.0277136258660508	0.722453527996253	0.907516492609032	0.999010790485549
GO:0015026	coreceptor activity	1/715	61/18639	0.0163934426229508	0.427352974893959	0.908367980552652	0.999010790485549
GO:0016836	hydro-lyase activity	1/715	61/18639	0.0163934426229508	0.427352974893959	0.908367980552652	0.999010790485549
GO:0019905	syntaxin binding	1/715	61/18639	0.0163934426229508	0.427352974893959	0.908367980552652	0.999010790485549
GO:0005253	monoatomic anion channel activity	2/715	103/18639	0.0194174757281553	0.506185077058863	0.909702265127964	0.999010790485549
GO:0004677	DNA-dependent protein kinase activity	6/715	246/18639	0.024390243902439	0.63581784069589	0.914055947142369	0.999010790485549
GO:0022824	transmitter-gated monoatomic ion channel activity	1/715	63/18639	0.0158730158730159	0.413786213786214	0.915285607351137	0.999010790485549
GO:0022835	transmitter-gated channel activity	1/715	63/18639	0.0158730158730159	0.413786213786214	0.915285607351137	0.999010790485549
GO:0000149	SNARE binding	2/715	106/18639	0.0188679245283019	0.491859084311914	0.91786117871298	0.999010790485549
GO:0004497	monooxygenase activity	2/715	106/18639	0.0188679245283019	0.491859084311914	0.91786117871298	0.999010790485549
GO:0120013	lipid transfer activity	1/715	65/18639	0.0153846153846154	0.4010543302851	0.921681672989157	0.999010790485549
GO:0160215	deacylase activity	1/715	65/18639	0.0153846153846154	0.4010543302851	0.921681672989157	0.999010790485549
GO:0035091	phosphatidylinositol binding	7/715	284/18639	0.0246478873239437	0.642534226337043	0.922581056888018	0.999010790485549
GO:0008235	metalloexopeptidase activity	1/715	66/18639	0.0151515151515152	0.394977749523204	0.924696511139945	0.999010790485549
GO:0003777	microtubule motor activity	1/715	68/18639	0.0147058823529412	0.383360756890169	0.930382939565913	0.999010790485549
GO:0016279	protein-lysine N-methyltransferase activity	1/715	69/18639	0.0144927536231884	0.37780480389176	0.933063258246133	0.999010790485549
GO:0098960	postsynaptic neurotransmitter receptor activity	1/715	69/18639	0.0144927536231884	0.37780480389176	0.933063258246133	0.999010790485549
GO:0046943	carboxylic acid transmembrane transporter activity	4/715	188/18639	0.0212765957446809	0.554649605713435	0.933317196527413	0.999010790485549
GO:0005342	organic acid transmembrane transporter activity	4/715	189/18639	0.0211640211640212	0.551714951714952	0.935007901294218	0.999010790485549
GO:0008028	monocarboxylic acid transmembrane transporter activity	1/715	70/18639	0.0142857142857143	0.372407592407592	0.935640521054642	0.999010790485549
GO:0016278	lysine N-methyltransferase activity	1/715	70/18639	0.0142857142857143	0.372407592407592	0.935640521054642	0.999010790485549
GO:0003774	cytoskeletal motor activity	3/715	153/18639	0.0196078431372549	0.511147675853558	0.936299753314254	0.999010790485549
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/715	73/18639	0.0136986301369863	0.357103170801801	0.942792792082453	0.999010790485549
GO:0035064	methylated histone binding	1/715	74/18639	0.0135135135135135	0.352277452277452	0.944995913576638	0.999010790485549
GO:0005543	phospholipid binding	13/715	497/18639	0.0261569416498994	0.681873056520944	0.946846014082331	0.999010790485549
GO:0140034	methylation-dependent protein binding	1/715	76/18639	0.0131578947368421	0.343006993006993	0.949151218247188	0.999010790485549
GO:0015108	chloride transmembrane transporter activity	2/715	121/18639	0.0165289256198347	0.430884817661677	0.94923555266459	0.999010790485549
GO:0015370	solute:sodium symporter activity	1/715	79/18639	0.0126582278481013	0.329981410994069	0.954803800366029	0.999010790485549
GO:0015103	inorganic anion transmembrane transporter activity	3/715	165/18639	0.0181818181818182	0.473973299427845	0.954835817699122	0.999010790485549
GO:0016874	ligase activity	3/715	167/18639	0.0179640718562874	0.468296972488589	0.957385404438246	0.999010790485549
GO:0030971	receptor tyrosine kinase binding	1/715	81/18639	0.0123456790123457	0.321833721833722	0.958219066267799	0.999010790485549
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	5/715	243/18639	0.0205761316872428	0.536389536389536	0.958768447374118	0.999010790485549
GO:0004676	3-phosphoinositide-dependent protein kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0004711	ribosomal protein S6 kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0035175	histone H3S10 kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0035979	histone H2AXS139 kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0044022	histone H3S28 kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0044023	histone H4S1 kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0044024	histone H2AS1 kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0044025	histone H2BS14 kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0072354	histone H3T3 kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0072371	histone H2AS121 kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0072518	Rho-dependent protein serine/threonine kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0140823	histone H2BS36 kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0140855	histone H3S57 kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0140995	histone H2A kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0140997	histone H4 kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0140998	histone H2B kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:1990244	histone H2AT120 kinase activity	5/715	245/18639	0.0204081632653061	0.532010846296561	0.960774804199887	0.999010790485549
GO:0140857	histone H3T45 kinase activity	5/715	246/18639	0.0203252032520325	0.529848200579908	0.961744075093196	0.999010790485549
GO:0015631	tubulin binding	9/715	385/18639	0.0233766233766234	0.609394242121515	0.962059853912472	0.999010790485549
GO:0016798	hydrolase activity, acting on glycosyl bonds	2/715	130/18639	0.0153846153846154	0.4010543302851	0.962173334606286	0.999010790485549
GO:0035402	histone H3T11 kinase activity	5/715	247/18639	0.0202429149797571	0.527703066164605	0.962691333107895	0.999010790485549
GO:0035403	histone H3T6 kinase activity	5/715	247/18639	0.0202429149797571	0.527703066164605	0.962691333107895	0.999010790485549
GO:0004679	AMP-activated protein kinase activity	5/715	248/18639	0.0201612903225806	0.525575231220393	0.963617014206791	0.999010790485549
GO:0141003	histone H2AX kinase activity	8/715	354/18639	0.0225988700564972	0.58911935522105	0.964222056162869	0.999010790485549
GO:0050660	flavin adenine dinucleotide binding	1/715	86/18639	0.0116279069767442	0.303122458936412	0.965671700716834	0.999010790485549
GO:0140996	histone H3 kinase activity	8/715	357/18639	0.0224089635854342	0.584168772404067	0.966471537916222	0.999010790485549
GO:0004252	serine-type endopeptidase activity	3/715	176/18639	0.0170454545454545	0.444349968213605	0.96727608409289	0.999010790485549
GO:0015297	antiporter activity	2/715	135/18639	0.0148148148148148	0.386200466200466	0.967926753695153	0.999010790485549
GO:0035173	histone kinase activity	8/715	360/18639	0.0222222222222222	0.579300699300699	0.968592335136117	0.999010790485549
GO:0106310	protein serine kinase activity	8/715	361/18639	0.0221606648199446	0.577695988222304	0.969271770261613	0.999010790485549
GO:0070851	growth factor receptor binding	2/715	139/18639	0.0143884892086331	0.375086783719877	0.971913637561755	0.999999936975931
GO:0043178	alcohol binding	1/715	92/18639	0.0108695652173913	0.28335360291882	0.972883708061603	0.999999936975931
GO:0030594	neurotransmitter receptor activity	1/715	97/18639	0.0103092783505155	0.268747747098263	0.977723198861787	0.999999936975931
GO:0030527	structural constituent of chromatin	1/715	98/18639	0.0102040816326531	0.26600542314828	0.978582216918838	0.999999936975931
GO:0008509	monoatomic anion transmembrane transporter activity	2/715	149/18639	0.0134228187919463	0.349913174074248	0.97989944297459	0.999999936975931
GO:0008236	serine-type peptidase activity	3/715	194/18639	0.0154639175257732	0.403121620647394	0.980928540121835	0.999999936975931
GO:0008238	exopeptidase activity	1/715	102/18639	0.00980392156862745	0.255573837926779	0.981699967077493	0.999999936975931
GO:0008017	microtubule binding	5/715	276/18639	0.0181159420289855	0.472256004864701	0.982347147585479	0.999999936975931
GO:0017171	serine hydrolase activity	3/715	198/18639	0.0151515151515152	0.394977749523204	0.983117593559628	0.999999936975931
GO:0004843	cysteine-type deubiquitinase activity	1/715	108/18639	0.00925925925925926	0.241375291375291	0.985547608898147	0.999999936975931
GO:0015291	secondary active transmembrane transporter activity	5/715	287/18639	0.0174216027874564	0.454155600497064	0.98684030365194	0.999999936975931
GO:0101005	deubiquitinase activity	1/715	115/18639	0.00869565217391304	0.226682882335056	0.989027656751311	0.999999936975931
GO:0008528	G protein-coupled peptide receptor activity	1/715	122/18639	0.00819672131147541	0.213676487446979	0.991670614838783	0.999999936975931
GO:0005319	lipid transporter activity	2/715	178/18639	0.0112359550561798	0.292904847961028	0.992522596866389	0.999999936975931
GO:0019783	ubiquitin-like protein peptidase activity	1/715	127/18639	0.0078740157480315	0.205264027311271	0.993159397197692	0.999999936975931
GO:0001653	peptide receptor activity	1/715	128/18639	0.0078125	0.203660402097902	0.993423605873343	0.999999936975931
GO:0022834	ligand-gated channel activity	2/715	188/18639	0.0106382978723404	0.277324802856718	0.994712157872635	0.999999936975931
GO:0099094	ligand-gated monoatomic cation channel activity	1/715	136/18639	0.00735294117647059	0.191680378445084	0.995201543499129	0.999999936975931
GO:0015081	sodium ion transmembrane transporter activity	1/715	164/18639	0.00609756097560976	0.158954460173972	0.998409536195186	0.999999936975931
GO:0015276	ligand-gated monoatomic ion channel activity	1/715	186/18639	0.00537634408602151	0.140153394992105	0.999332897880216	0.999999936975931
GO:0005261	monoatomic cation channel activity	3/715	341/18639	0.00879765395894428	0.229341919077989	0.999842857030947	0.999999936975931
GO:0005216	monoatomic ion channel activity	5/715	448/18639	0.0111607142857143	0.290943431568432	0.999885621550694	0.999999936975931
GO:0045182	translation regulator activity	3/715	356/18639	0.00842696629213483	0.219678635970771	0.999906236100106	0.999999936975931
GO:0022836	gated channel activity	2/715	318/18639	0.00628930817610063	0.163953028103971	0.999950573220547	0.999999936975931
GO:0046873	metal ion transmembrane transporter activity	4/715	450/18639	0.00888888888888889	0.23172027972028	0.999977847593641	0.999999936975931
GO:0030371	translation repressor activity	1/715	329/18639	0.00303951367781155	0.0792356579590622	0.999997707569653	0.999999936975931
GO:0004984	olfactory receptor activity	1/715	419/18639	0.00238663484486874	0.0622160655573543	0.999999936975931	0.999999936975931