ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	102/2249	175/18639	0.582857142857143	4.83053547608461	9.53796000250044e-49	1.22848924832206e-45
GO:0019843	rRNA binding	36/2249	65/18639	0.553846153846154	4.59010158360981	4.78583100256484e-17	3.08207516565176e-14
GO:0038024	cargo receptor activity	27/2249	65/18639	0.415384615384615	3.44257618770736	1.95051636860809e-09	8.37421694255742e-07
GO:0009055	electron transfer activity	36/2249	116/18639	0.310344827586207	2.57203968047101	4.69759295688511e-08	1.32409077742319e-05
GO:0003712	transcription coregulator activity	101/2249	495/18639	0.204040404040404	1.69102227252516	6.01463618791265e-08	1.32409077742319e-05
GO:0042605	peptide antigen binding	20/2249	45/18639	0.444444444444444	3.68341485104491	6.16812473954904e-08	1.32409077742319e-05
GO:0003697	single-stranded DNA binding	35/2249	121/18639	0.289256198347107	2.39726379768419	4.84890822875088e-07	8.92199114090162e-05
GO:0048027	mRNA 5'-UTR binding	13/2249	24/18639	0.541666666666667	4.48916184971098	7.61399497961482e-07	0.000122585319171799
GO:0031072	heat shock protein binding	36/2249	131/18639	0.274809160305344	2.27753132011174	1.30189045063944e-06	0.000186314988935956
GO:0003713	transcription coactivator activity	57/2249	256/18639	0.22265625	1.84530451033793	2.88309077685143e-06	0.000371342092058465
GO:0044389	ubiquitin-like protein ligase binding	67/2249	322/18639	0.208074534161491	1.72445586582304	4.94760998809086e-06	0.00057932015133282
GO:0140297	DNA-binding transcription factor binding	92/2249	488/18639	0.188524590163934	1.56243211919323	7.81081955918188e-06	0.000782308205015365
GO:0031625	ubiquitin protein ligase binding	63/2249	302/18639	0.208609271523179	1.72888759978681	8.59935383381868e-06	0.000782308205015365
GO:1990841	promoter-specific chromatin binding	22/2249	68/18639	0.323529411764706	2.68130934009887	8.7978345500339e-06	0.000782308205015365
GO:0045296	cadherin binding	68/2249	334/18639	0.203592814371257	1.68731279104752	9.1107322012659e-06	0.000782308205015365
GO:0003746	translation elongation factor activity	10/2249	18/18639	0.555555555555556	4.60426856380614	1.11834242011335e-05	0.000884685276489572
GO:0042277	peptide binding	54/2249	249/18639	0.216867469879518	1.79732893334119	1.16767466617412e-05	0.000884685276489572
GO:0044183	protein folding chaperone	23/2249	75/18639	0.306666666666667	2.54155624722099	1.49977148451942e-05	0.00102768772876473
GO:0015078	proton transmembrane transporter activity	43/2249	185/18639	0.232432432432432	1.92632641534376	1.51599897876785e-05	0.00102768772876473
GO:0016504	peptidase activator activity	19/2249	57/18639	0.333333333333333	2.76256113828368	2.20802848076436e-05	0.00142197034161225
GO:0008135	translation factor activity, RNA binding	24/2249	83/18639	0.289156626506024	2.39643857778825	2.93991800597029e-05	0.00177148558752446
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	21/2249	68/18639	0.308823529411765	2.55943164282165	3.09539616052687e-05	0.00177148558752446
GO:0051082	unfolded protein binding	31/2249	121/18639	0.256198347107438	2.12329079223457	3.16336712057939e-05	0.00177148558752446
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	18/2249	54/18639	0.333333333333333	2.76256113828368	3.60995661904937e-05	0.0018804944569388
GO:0180051	translation factor activity	24/2249	84/18639	0.285714285714286	2.3679095471003	3.65002806082842e-05	0.0018804944569388
GO:0140416	transcription regulator inhibitor activity	13/2249	33/18639	0.393939393939394	3.26484498160799	6.10337341718134e-05	0.00302351729281907
GO:1990948	ubiquitin ligase inhibitor activity	7/2249	11/18639	0.636363636363636	5.27398035490521	7.82003316272319e-05	0.00373044544947684
GO:0016887	ATP hydrolysis activity	77/2249	417/18639	0.184652278177458	1.53033962336578	8.52814804768632e-05	0.00392294810193571
GO:0030228	lipoprotein particle receptor activity	9/2249	18/18639	0.5	4.14384170742552	9.32138748375714e-05	0.00413998175140662
GO:0055105	ubiquitin-protein transferase inhibitor activity	8/2249	15/18639	0.533333333333333	4.42009782125389	0.00013007513799648	0.00558455925798219
GO:0015036	disulfide oxidoreductase activity	14/2249	40/18639	0.35	2.90068919519787	0.000144934719443512	0.00583362245760134
GO:0140662	ATP-dependent protein folding chaperone	14/2249	40/18639	0.35	2.90068919519787	0.000144934719443512	0.00583362245760134
GO:0023026	MHC class II protein complex binding	11/2249	27/18639	0.407407407407407	3.37646361345783	0.00015776977578944	0.00599148297892856
GO:0008301	DNA binding, bending	9/2249	19/18639	0.473684210526316	3.92574477545576	0.000158160264971717	0.00599148297892856
GO:0001618	virus receptor activity	22/2249	81/18639	0.271604938271605	2.25097574230522	0.000172204445415847	0.00620976640376886
GO:0055106	ubiquitin-protein transferase regulator activity	13/2249	36/18639	0.361111111111111	2.99277456647399	0.000173564899484223	0.00620976640376886
GO:0140272	exogenous protein binding	22/2249	82/18639	0.268292682926829	2.22352481861857	0.000208876140824422	0.00727114782113124
GO:0097718	disordered domain specific binding	11/2249	28/18639	0.392857142857143	3.25587562726291	0.000231664602244392	0.00785221072870467
GO:0022853	active monoatomic ion transmembrane transporter activity	28/2249	118/18639	0.23728813559322	1.96656894589686	0.000304649674224665	0.0100612507795223
GO:0015399	primary active transmembrane transporter activity	36/2249	166/18639	0.216867469879518	1.79732893334119	0.000313756167492466	0.0101029485932574
GO:0008035	high-density lipoprotein particle binding	7/2249	13/18639	0.538461538461538	4.46259876184287	0.000326171103951452	0.0102465458997432
GO:0016860	intramolecular oxidoreductase activity	16/2249	53/18639	0.30188679245283	2.5019421629739	0.000354195045407314	0.0106416680303414
GO:0140104	molecular carrier activity	49/2249	249/18639	0.196787148594378	1.63090958766145	0.000355273078652701	0.0106416680303414
GO:0016922	nuclear receptor binding	31/2249	137/18639	0.226277372262774	1.87531522525827	0.00036727668237253	0.0107511901567232
GO:0016209	antioxidant activity	22/2249	86/18639	0.255813953488372	2.12010505961306	0.000433397821076459	0.0121643798534281
GO:0003725	double-stranded RNA binding	20/2249	75/18639	0.266666666666667	2.21004891062694	0.000434442137622432	0.0121643798534281
GO:0051087	protein-folding chaperone binding	30/2249	134/18639	0.223880597014925	1.85545151078755	0.000547390643348547	0.0148345494433564
GO:0043021	ribonucleoprotein complex binding	37/2249	177/18639	0.209039548022599	1.73245359519485	0.000552840351926324	0.0148345494433564
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	13/2249	40/18639	0.325	2.69349710982659	0.000568347068325263	0.0149394086531212
GO:0061133	endopeptidase activator activity	9/2249	22/18639	0.409090909090909	3.39041594243906	0.000607137201864729	0.0156398543200354
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	63/2249	349/18639	0.180515759312321	1.49605746457197	0.000666114306390727	0.0168226515025737
GO:0042608	T cell receptor binding	6/2249	11/18639	0.545454545454545	4.52055458991875	0.000824550430326799	0.020423479889633
GO:0004601	peroxidase activity	16/2249	57/18639	0.280701754385965	2.32636727434415	0.000864546475352326	0.0210101105708263
GO:0140597	protein carrier chaperone	38/2249	188/18639	0.202127659574468	1.67517005193798	0.000919657636307167	0.0219355376956228
GO:0023023	MHC protein complex binding	12/2249	37/18639	0.324324324324324	2.68789732373547	0.000938522058867635	0.0219784802149366
GO:0004857	enzyme inhibitor activity	72/2249	416/18639	0.173076923076923	1.43440674487807	0.000980261405819717	0.0225460123338535
GO:0042826	histone deacetylase binding	28/2249	127/18639	0.220472440944882	1.82720579225062	0.00105873321222797	0.0234074198972465
GO:0017124	SH3 domain binding	26/2249	115/18639	0.226086956521739	1.87373711987937	0.00106492277271836	0.0234074198972465
GO:0051537	2 iron, 2 sulfur cluster binding	10/2249	28/18639	0.357142857142857	2.95988693387537	0.00107223429653536	0.0234074198972465
GO:0008094	ATP-dependent activity, acting on DNA	41/2249	210/18639	0.195238095238095	1.61807152385187	0.00120755040443196	0.0259220820151393
GO:0030215	semaphorin receptor binding	9/2249	24/18639	0.375	3.10788128056914	0.00127471989424175	0.0264812778029576
GO:0050699	WW domain binding	9/2249	24/18639	0.375	3.10788128056914	0.00127471989424175	0.0264812778029576
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	16/2249	59/18639	0.271186440677966	2.24750736673927	0.00129655671261471	0.0265073816801229
GO:0015035	protein-disulfide reductase activity	11/2249	34/18639	0.323529411764706	2.68130934009887	0.00155405150453811	0.0312752865288295
GO:0140313	molecular sequestering activity	15/2249	55/18639	0.272727272727273	2.26027729495938	0.00170672474738334	0.0338194073019961
GO:0001848	complement binding	9/2249	25/18639	0.36	2.98356602934638	0.00178056852217249	0.0347480644933056
GO:0001846	opsonin binding	8/2249	21/18639	0.380952380952381	3.15721272946706	0.00210967778129059	0.0405561937657057
GO:0140658	ATP-dependent chromatin remodeler activity	32/2249	158/18639	0.20253164556962	1.67851815996983	0.0021587316874493	0.0408889178446279
GO:0003714	transcription corepressor activity	39/2249	204/18639	0.191176470588235	1.58441006460388	0.00232594464750727	0.0434176334201358
GO:0005542	folic acid binding	6/2249	13/18639	0.461538461538462	3.82508465300817	0.00247091353443905	0.0454648090336786
GO:0003689	DNA clamp loader activity	32/2249	160/18639	0.2	1.65753668297021	0.00265702963788921	0.048200763008469
GO:0016853	isomerase activity	35/2249	180/18639	0.194444444444444	1.61149399733215	0.00283192188632456	0.0506599359664726
GO:0019207	kinase regulator activity	51/2249	287/18639	0.177700348432056	1.4727242305136	0.0028789969256764	0.0507965484968659
GO:0140097	catalytic activity, acting on DNA	58/2249	336/18639	0.172619047619048	1.43061201803976	0.00305994351016642	0.0532595573120858
GO:0019887	protein kinase regulator activity	46/2249	255/18639	0.180392156862745	1.49503308660058	0.00334128815685116	0.0561193740772294
GO:0071813	lipoprotein particle binding	10/2249	32/18639	0.3125	2.58990106714095	0.00335496258070393	0.0561193740772294
GO:0071814	protein-lipid complex binding	10/2249	32/18639	0.3125	2.58990106714095	0.00335496258070393	0.0561193740772294
GO:0051536	iron-sulfur cluster binding	18/2249	76/18639	0.236842105263158	1.96287238772788	0.00348556809054554	0.0563546969241128
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	7/2249	18/18639	0.388888888888889	3.2229879946643	0.00350029173441695	0.0563546969241128
GO:1901611	phosphatidylglycerol binding	7/2249	18/18639	0.388888888888889	3.2229879946643	0.00350029173441695	0.0563546969241128
GO:0005345	purine nucleobase transmembrane transporter activity	5/2249	10/18639	0.5	4.14384170742552	0.00379707020844844	0.0578673134750966
GO:0015658	branched-chain amino acid transmembrane transporter activity	5/2249	10/18639	0.5	4.14384170742552	0.00379707020844844	0.0578673134750966
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	5/2249	10/18639	0.5	4.14384170742552	0.00379707020844844	0.0578673134750966
GO:0000510	H3-H4 histone complex chaperone activity	30/2249	151/18639	0.198675496688742	1.64655961884458	0.00392115607370059	0.0578673134750966
GO:0140584	chromatin extrusion motor activity	30/2249	151/18639	0.198675496688742	1.64655961884458	0.00392115607370059	0.0578673134750966
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	30/2249	151/18639	0.198675496688742	1.64655961884458	0.00392115607370059	0.0578673134750966
GO:0140849	ATP-dependent H2AZ histone chaperone activity	30/2249	151/18639	0.198675496688742	1.64655961884458	0.00392115607370059	0.0578673134750966
GO:0140713	histone chaperone activity	32/2249	164/18639	0.195121951219512	1.61710895899533	0.0039536673802861	0.0578673134750966
GO:0051540	metal cluster binding	18/2249	77/18639	0.233766233766234	1.93738053853661	0.00404663879934565	0.0585625929613168
GO:0140311	protein sequestering activity	10/2249	33/18639	0.303030303030303	2.51141921662153	0.00430137288552276	0.0593951111409754
GO:0019789	SUMO transferase activity	9/2249	28/18639	0.321428571428571	2.66389824048784	0.00430574158857758	0.0593951111409754
GO:0045499	chemorepellent activity	9/2249	28/18639	0.321428571428571	2.66389824048784	0.00430574158857758	0.0593951111409754
GO:0015616	DNA translocase activity	30/2249	152/18639	0.197368421052632	1.63572698977323	0.00433473637208982	0.0593951111409754
GO:0140674	ATP-dependent histone chaperone activity	30/2249	152/18639	0.197368421052632	1.63572698977323	0.00433473637208982	0.0593951111409754
GO:0061775	cohesin loader activity	30/2249	153/18639	0.196078431372549	1.62503596369628	0.00478448105873968	0.0648674905648075
GO:0003756	protein disulfide isomerase activity	7/2249	19/18639	0.368421052631579	3.0533570475767	0.00497156359360527	0.0660141640058102
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	7/2249	19/18639	0.368421052631579	3.0533570475767	0.00497156359360527	0.0660141640058102
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	15/2249	61/18639	0.245901639344262	2.03795493807813	0.00504569817018522	0.0663148902367201
GO:0000217	DNA secondary structure binding	11/2249	39/18639	0.282051282051282	2.33755173239388	0.00516017050352443	0.0671343394801966
GO:0004386	helicase activity	30/2249	155/18639	0.193548387096774	1.60406775771311	0.00580218217455516	0.0714114967109132
GO:0004129	cytochrome-c oxidase activity	6/2249	15/18639	0.4	3.31507336594042	0.00582158940578097	0.0714114967109132
GO:0005041	low-density lipoprotein particle receptor activity	6/2249	15/18639	0.4	3.31507336594042	0.00582158940578097	0.0714114967109132
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	6/2249	15/18639	0.4	3.31507336594042	0.00582158940578097	0.0714114967109132
GO:0031386	protein tag activity	6/2249	15/18639	0.4	3.31507336594042	0.00582158940578097	0.0714114967109132
GO:0141047	molecular tag activity	6/2249	15/18639	0.4	3.31507336594042	0.00582158940578097	0.0714114967109132
GO:0001851	complement component C3b binding	5/2249	11/18639	0.454545454545455	3.76712882493229	0.0062741700235498	0.0755245886946929
GO:0015205	nucleobase transmembrane transporter activity	5/2249	11/18639	0.454545454545455	3.76712882493229	0.0062741700235498	0.0755245886946929
GO:0030544	Hsp70 protein binding	13/2249	51/18639	0.254901960784314	2.11254675280517	0.00634226218242439	0.0756373489903946
GO:0042288	MHC class I protein binding	7/2249	20/18639	0.35	2.90068919519787	0.00686296787223842	0.0810963543068172
GO:0022804	active transmembrane transporter activity	73/2249	457/18639	0.159737417943107	1.32385314941822	0.00730088705582598	0.0854867502536715
GO:0001530	lipopolysaccharide binding	11/2249	41/18639	0.268292682926829	2.22352481861857	0.00775959194032386	0.0900392290012354
GO:0003688	DNA replication origin binding	6/2249	16/18639	0.375	3.10788128056914	0.00837561422084172	0.0938068792734273
GO:0005159	insulin-like growth factor receptor binding	6/2249	16/18639	0.375	3.10788128056914	0.00837561422084172	0.0938068792734273
GO:0016675	oxidoreductase activity, acting on a heme group of donors	6/2249	16/18639	0.375	3.10788128056914	0.00837561422084172	0.0938068792734273
GO:0017070	U6 snRNA binding	6/2249	16/18639	0.375	3.10788128056914	0.00837561422084172	0.0938068792734273
GO:0008017	microtubule binding	47/2249	276/18639	0.170289855072464	1.41130840760145	0.00913486540980052	0.100852724050962
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	7/2249	21/18639	0.333333333333333	2.76256113828368	0.00923961291771236	0.100852724050962
GO:0070182	DNA polymerase binding	7/2249	21/18639	0.333333333333333	2.76256113828368	0.00923961291771236	0.100852724050962
GO:0097371	MDM2/MDM4 family protein binding	5/2249	12/18639	0.416666666666667	3.4532014228546	0.00969783974560285	0.104964853717113
GO:0038187	pattern recognition receptor activity	12/2249	48/18639	0.25	2.07192085371276	0.0100545540034355	0.107918879636875
GO:0019210	kinase inhibitor activity	19/2249	90/18639	0.211111111111111	1.74962205424633	0.010143591535421	0.107974759484481
GO:0004860	protein kinase inhibitor activity	18/2249	84/18639	0.214285714285714	1.77593216032522	0.0104015874780468	0.109813480915772
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	6/2249	17/18639	0.352941176470588	2.92506473465331	0.0116431222560236	0.120669999644087
GO:0016763	pentosyltransferase activity	12/2249	49/18639	0.244897959183673	2.0296367546574	0.0118894053372699	0.120669999644087
GO:0060590	ATPase regulator activity	12/2249	49/18639	0.244897959183673	2.0296367546574	0.0118894053372699	0.120669999644087
GO:0001671	ATPase activator activity	8/2249	27/18639	0.296296296296296	2.45560990069661	0.0118983617661483	0.120669999644087
GO:0005044	scavenger receptor activity	8/2249	27/18639	0.296296296296296	2.45560990069661	0.0118983617661483	0.120669999644087
GO:0070034	telomerase RNA binding	7/2249	22/18639	0.318181818181818	2.6369901774526	0.0121662384935289	0.121473761082677
GO:0140517	protein-RNA adaptor activity	7/2249	22/18639	0.318181818181818	2.6369901774526	0.0121662384935289	0.121473761082677
GO:0019903	protein phosphatase binding	27/2249	144/18639	0.1875	1.55394064028457	0.0129225016032838	0.127054824923889
GO:0019955	cytokine binding	27/2249	144/18639	0.1875	1.55394064028457	0.0129225016032838	0.127054824923889
GO:0001216	DNA-binding transcription activator activity	76/2249	491/18639	0.154786150712831	1.28281861411136	0.0132123114860735	0.128199525331533
GO:0061134	peptidase regulator activity	39/2249	226/18639	0.172566371681416	1.43017545654509	0.0133487338637741	0.128199525331533
GO:0001046	core promoter sequence-specific DNA binding	11/2249	44/18639	0.25	2.07192085371276	0.0134370620495008	0.128199525331533
GO:0003954	NADH dehydrogenase activity	11/2249	44/18639	0.25	2.07192085371276	0.0134370620495008	0.128199525331533
GO:0046966	nuclear thyroid hormone receptor binding	8/2249	28/18639	0.285714285714286	2.3679095471003	0.0149354098371766	0.141447116693261
GO:0042171	lysophosphatidic acid acyltransferase activity	7/2249	23/18639	0.304347826086957	2.52233843060684	0.0157057348667628	0.145613844040814
GO:0071617	lysophospholipid acyltransferase activity	7/2249	23/18639	0.304347826086957	2.52233843060684	0.0157057348667628	0.145613844040814
GO:0008525	phosphatidylcholine transporter activity	6/2249	18/18639	0.333333333333333	2.76256113828368	0.015714537516827	0.145613844040814
GO:0002039	p53 binding	15/2249	69/18639	0.217391304347826	1.80167030757631	0.0161392395221204	0.148481003603508
GO:0090482	vitamin transmembrane transporter activity	9/2249	34/18639	0.264705882352941	2.19379855098998	0.0168205730034972	0.153651759067407
GO:0004177	aminopeptidase activity	10/2249	40/18639	0.25	2.07192085371276	0.0180120081376902	0.163376524516514
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	13/2249	58/18639	0.224137931034483	1.85758421367351	0.0189327764594841	0.170527385173535
GO:0061665	SUMO ligase activity	5/2249	14/18639	0.357142857142857	2.95988693387537	0.0199529495233364	0.178468048514287
GO:0005154	epidermal growth factor receptor binding	9/2249	35/18639	0.257142857142857	2.13111859239027	0.0202838494394771	0.180176538469286
GO:0002020	protease binding	25/2249	136/18639	0.183823529411765	1.52347121596527	0.0205305016229042	0.181118397878771
GO:0008137	NADH dehydrogenase (ubiquinone) activity	10/2249	41/18639	0.24390243902439	2.02138619874416	0.0213192391690988	0.184289798991941
GO:0042169	SH2 domain binding	10/2249	41/18639	0.24390243902439	2.02138619874416	0.0213192391690988	0.184289798991941
GO:0042287	MHC protein binding	10/2249	41/18639	0.24390243902439	2.02138619874416	0.0213192391690988	0.184289798991941
GO:0036002	pre-mRNA binding	13/2249	59/18639	0.220338983050847	1.82609973547565	0.0216818974537153	0.186175226135902
GO:0004090	carbonyl reductase (NADPH) activity	4/2249	10/18639	0.4	3.31507336594042	0.0243520334403073	0.206351441257341
GO:0005522	profilin binding	4/2249	10/18639	0.4	3.31507336594042	0.0243520334403073	0.206351441257341
GO:0035198	miRNA binding	10/2249	42/18639	0.238095238095238	1.97325795591692	0.0250464925870659	0.208859189618192
GO:0003925	G protein activity	12/2249	54/18639	0.222222222222222	1.84170742552245	0.0251475299747343	0.208859189618192
GO:0017069	snRNA binding	12/2249	54/18639	0.222222222222222	1.84170742552245	0.0251475299747343	0.208859189618192
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	11/2249	48/18639	0.229166666666667	1.89926078257003	0.0252966099227003	0.208859189618192
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	73/2249	484/18639	0.150826446280992	1.2500018373639	0.0256627853048109	0.210532913838194
GO:0043022	ribosome binding	21/2249	112/18639	0.1875	1.55394064028457	0.0260542811024702	0.212391861139124
GO:0016004	phospholipase activator activity	6/2249	20/18639	0.3	2.48630502445531	0.0265913468743244	0.212730774994595
GO:0016505	peptidase activator activity involved in apoptotic process	6/2249	20/18639	0.3	2.48630502445531	0.0265913468743244	0.212730774994595
GO:0043024	ribosomal small subunit binding	6/2249	20/18639	0.3	2.48630502445531	0.0265913468743244	0.212730774994595
GO:0016411	acylglycerol O-acyltransferase activity	8/2249	31/18639	0.258064516129032	2.13875701028414	0.0273648334785715	0.217567318027161
GO:0008374	O-acyltransferase activity	12/2249	55/18639	0.218181818181818	1.8082218359675	0.0287488411875176	0.227168757359034
GO:0003684	damaged DNA binding	15/2249	74/18639	0.202702702702703	1.67993582733467	0.0293179847306522	0.228857965655031
GO:0031491	nucleosome binding	15/2249	74/18639	0.202702702702703	1.67993582733467	0.0293179847306522	0.228857965655031
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	7/2249	26/18639	0.269230769230769	2.23129938092144	0.030573994864235	0.235804223863082
GO:0050681	nuclear androgen receptor binding	7/2249	26/18639	0.269230769230769	2.23129938092144	0.030573994864235	0.235804223863082
GO:0016410	N-acyltransferase activity	18/2249	94/18639	0.191489361702128	1.58700320709914	0.0309489397606018	0.23727520483128
GO:0031490	chromatin DNA binding	23/2249	128/18639	0.1796875	1.48919311360605	0.0323622919745767	0.246642793273697
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	6/2249	21/18639	0.285714285714286	2.3679095471003	0.0335320404569693	0.25095913789803
GO:0042162	telomeric DNA binding	9/2249	38/18639	0.236842105263158	1.96287238772788	0.0337101677992667	0.25095913789803
GO:0043531	ADP binding	9/2249	38/18639	0.236842105263158	1.96287238772788	0.0337101677992667	0.25095913789803
GO:0001221	transcription coregulator binding	21/2249	115/18639	0.182608695652174	1.5134030583641	0.0338564809354081	0.25095913789803
GO:0008199	ferric iron binding	4/2249	11/18639	0.363636363636364	3.01370305994583	0.034682241107026	0.25095913789803
GO:0010854	adenylate cyclase regulator activity	4/2249	11/18639	0.363636363636364	3.01370305994583	0.034682241107026	0.25095913789803
GO:0015173	aromatic amino acid transmembrane transporter activity	4/2249	11/18639	0.363636363636364	3.01370305994583	0.034682241107026	0.25095913789803
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	4/2249	11/18639	0.363636363636364	3.01370305994583	0.034682241107026	0.25095913789803
GO:0070990	snRNP binding	4/2249	11/18639	0.363636363636364	3.01370305994583	0.034682241107026	0.25095913789803
GO:0004620	phospholipase activity	20/2249	109/18639	0.18348623853211	1.52067585593597	0.036055792654171	0.259440563902639
GO:0004364	glutathione transferase activity	7/2249	27/18639	0.259259259259259	2.14865866310953	0.0371104664485653	0.264078899368796
GO:0015252	proton channel activity	7/2249	27/18639	0.259259259259259	2.14865866310953	0.0371104664485653	0.264078899368796
GO:0003743	translation initiation factor activity	11/2249	51/18639	0.215686274509804	1.78753956006591	0.0381827269402145	0.270216221423056
GO:0008970	phospholipase A1 activity	6/2249	22/18639	0.272727272727273	2.26027729495938	0.0415442161932593	0.290792545798966
GO:0017116	single-stranded DNA helicase activity	12/2249	58/18639	0.206896551724138	1.71469312031401	0.0417675628670875	0.290792545798966
GO:0061980	regulatory RNA binding	12/2249	58/18639	0.206896551724138	1.71469312031401	0.0417675628670875	0.290792545798966
GO:0030695	GTPase regulator activity	72/2249	489/18639	0.147239263803681	1.22027240464064	0.0421257413478562	0.291709434709886
GO:0060589	nucleoside-triphosphatase regulator activity	72/2249	490/18639	0.146938775510204	1.21778205279444	0.0437406795062902	0.301272701626213
GO:0050698	proteoglycan sulfotransferase activity	7/2249	28/18639	0.25	2.07192085371276	0.0445021519856948	0.304887083816888
GO:0030169	low-density lipoprotein particle binding	5/2249	17/18639	0.294117647058824	2.43755394554442	0.0454300629809257	0.305719082123887
GO:1990226	histone methyltransferase binding	5/2249	17/18639	0.294117647058824	2.43755394554442	0.0454300629809257	0.305719082123887
GO:0030331	nuclear estrogen receptor binding	9/2249	40/18639	0.225	1.86472876834149	0.045472360795354	0.305719082123887
GO:0030332	cyclin binding	8/2249	34/18639	0.235294117647059	1.95004315643554	0.0455730308756106	0.305719082123887
GO:0070063	RNA polymerase binding	12/2249	59/18639	0.203389830508475	1.68563052505445	0.0468958178662464	0.310003474605133
GO:0008179	adenylate cyclase binding	4/2249	12/18639	0.333333333333333	2.76256113828368	0.0471744417877376	0.310003474605133
GO:0097677	STAT family protein binding	4/2249	12/18639	0.333333333333333	2.76256113828368	0.0471744417877376	0.310003474605133
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/2249	12/18639	0.333333333333333	2.76256113828368	0.0471744417877376	0.310003474605133
GO:1901505	carbohydrate derivative transmembrane transporter activity	11/2249	53/18639	0.207547169811321	1.72008523704456	0.0489618306255453	0.320115928150773
GO:0008171	O-methyltransferase activity	6/2249	23/18639	0.260869565217391	2.16200436909158	0.0506636801908463	0.327941220294259
GO:0050660	flavin adenine dinucleotide binding	16/2249	86/18639	0.186046511627907	1.5418945888095	0.0506679369864577	0.327941220294259
GO:0051287	NAD binding	11/2249	54/18639	0.203703703703704	1.68823180672892	0.05505386102459	0.35454686499836
GO:0016854	racemase and epimerase activity	5/2249	18/18639	0.277777777777778	2.30213428190307	0.0568591112363483	0.360761257499589
GO:0031690	adrenergic receptor binding	5/2249	18/18639	0.277777777777778	2.30213428190307	0.0568591112363483	0.360761257499589
GO:0034185	apolipoprotein binding	5/2249	18/18639	0.277777777777778	2.30213428190307	0.0568591112363483	0.360761257499589
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	21/2249	122/18639	0.172131147540984	1.42656845665469	0.0586225154321466	0.370126469983357
GO:0035035	histone acetyltransferase binding	6/2249	24/18639	0.25	2.07192085371276	0.0609123272111733	0.372872355971394
GO:0042625	ATPase-coupled ion transmembrane transporter activity	6/2249	24/18639	0.25	2.07192085371276	0.0609123272111733	0.372872355971394
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	6/2249	24/18639	0.25	2.07192085371276	0.0609123272111733	0.372872355971394
GO:0046961	proton-transporting ATPase activity, rotational mechanism	6/2249	24/18639	0.25	2.07192085371276	0.0609123272111733	0.372872355971394
GO:0060229	lipase activator activity	6/2249	24/18639	0.25	2.07192085371276	0.0609123272111733	0.372872355971394
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	4/2249	13/18639	0.307692307692308	2.55005643533878	0.0618232298589185	0.372872355971394
GO:0005172	vascular endothelial growth factor receptor binding	4/2249	13/18639	0.307692307692308	2.55005643533878	0.0618232298589185	0.372872355971394
GO:0097157	pre-mRNA intronic binding	4/2249	13/18639	0.307692307692308	2.55005643533878	0.0618232298589185	0.372872355971394
GO:0008187	poly-pyrimidine tract binding	7/2249	30/18639	0.233333333333333	1.93379279679858	0.0619523945480421	0.372872355971394
GO:0035925	mRNA 3'-UTR AU-rich region binding	7/2249	30/18639	0.233333333333333	1.93379279679858	0.0619523945480421	0.372872355971394
GO:0003727	single-stranded RNA binding	16/2249	89/18639	0.179775280898876	1.48992061390581	0.0658114958058857	0.394256774874329
GO:0070003	threonine-type peptidase activity	5/2249	19/18639	0.263157894736842	2.18096931969764	0.0697827819730088	0.416112144357571
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	22/2249	132/18639	0.166666666666667	1.38128056914184	0.0720504803385247	0.427654463944792
GO:0019902	phosphatase binding	30/2249	190/18639	0.157894736842105	1.30858159181859	0.0742994890971992	0.438980467693544
GO:0015932	nucleobase-containing compound transmembrane transporter activity	11/2249	57/18639	0.192982456140351	1.59937750111161	0.0762698970675009	0.448564508780553
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	16/2249	91/18639	0.175824175824176	1.45717510590788	0.0774466579479209	0.44977728216524
GO:0016530	metallochaperone activity	4/2249	14/18639	0.285714285714286	2.3679095471003	0.0785713419931515	0.44977728216524
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	4/2249	14/18639	0.285714285714286	2.3679095471003	0.0785713419931515	0.44977728216524
GO:0070742	C2H2 zinc finger domain binding	4/2249	14/18639	0.285714285714286	2.3679095471003	0.0785713419931515	0.44977728216524
GO:0098847	sequence-specific single stranded DNA binding	4/2249	14/18639	0.285714285714286	2.3679095471003	0.0785713419931515	0.44977728216524
GO:1901612	cardiolipin binding	4/2249	14/18639	0.285714285714286	2.3679095471003	0.0785713419931515	0.44977728216524
GO:0140299	molecular sensor activity	13/2249	71/18639	0.183098591549296	1.51746316046568	0.0809384789494921	0.459706378830641
GO:0016597	amino acid binding	10/2249	51/18639	0.196078431372549	1.62503596369628	0.0810196801199966	0.459706378830641
GO:0051059	NF-kappaB binding	7/2249	32/18639	0.21875	1.81293074699867	0.0830424238522022	0.466846849477671
GO:0005326	neurotransmitter transmembrane transporter activity	5/2249	20/18639	0.25	2.07192085371276	0.0841799270059036	0.466846849477671
GO:0010851	cyclase regulator activity	5/2249	20/18639	0.25	2.07192085371276	0.0841799270059036	0.466846849477671
GO:0008198	ferrous iron binding	6/2249	26/18639	0.230769230769231	1.91254232650409	0.0848153437715645	0.466846849477671
GO:0030247	polysaccharide binding	6/2249	26/18639	0.230769230769231	1.91254232650409	0.0848153437715645	0.466846849477671
GO:0050750	low-density lipoprotein particle receptor binding	6/2249	26/18639	0.230769230769231	1.91254232650409	0.0848153437715645	0.466846849477671
GO:0070006	metalloaminopeptidase activity	6/2249	26/18639	0.230769230769231	1.91254232650409	0.0848153437715645	0.466846849477671
GO:0051539	4 iron, 4 sulfur cluster binding	9/2249	45/18639	0.2	1.65753668297021	0.0858386941736772	0.470469098279559
GO:0008201	heparin binding	27/2249	172/18639	0.156976744186047	1.30097355930801	0.0915305207463738	0.499539452209023
GO:0042393	histone binding	37/2249	247/18639	0.149797570850202	1.2414748435202	0.0964984523108776	0.517955803043063
GO:0048306	calcium-dependent protein binding	14/2249	80/18639	0.175	1.45034459759893	0.0970007148470521	0.517955803043063
GO:0034483	heparan sulfate sulfotransferase activity	4/2249	15/18639	0.266666666666667	2.21004891062694	0.0973177828698922	0.517955803043063
GO:0042809	nuclear vitamin D receptor binding	4/2249	15/18639	0.266666666666667	2.21004891062694	0.0973177828698922	0.517955803043063
GO:0050780	dopamine receptor binding	4/2249	15/18639	0.266666666666667	2.21004891062694	0.0973177828698922	0.517955803043063
GO:0140776	protein-containing complex destabilizing activity	4/2249	15/18639	0.266666666666667	2.21004891062694	0.0973177828698922	0.517955803043063
GO:0008146	sulfotransferase activity	10/2249	53/18639	0.188679245283019	1.56371385185869	0.0995319409411524	0.525398114476247
GO:0140296	general transcription initiation factor binding	10/2249	53/18639	0.188679245283019	1.56371385185869	0.0995319409411524	0.525398114476247
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5/2249	21/18639	0.238095238095238	1.97325795591692	0.100007391552446	0.525753144161429
GO:0005096	GTPase activator activity	40/2249	271/18639	0.14760147601476	1.22327430477506	0.102901956948236	0.538771221745235
GO:0015631	tubulin binding	55/2249	385/18639	0.142857142857143	1.18395477355015	0.103533639897977	0.539883919791878
GO:0003678	DNA helicase activity	13/2249	74/18639	0.175675675675676	1.45594438369005	0.104522820670998	0.540929938517565
GO:0016651	oxidoreductase activity, acting on NAD(P)H	15/2249	88/18639	0.170454545454545	1.41267330934961	0.104891004592456	0.540929938517565
GO:0140463	chromatin-protein adaptor activity	10/2249	54/18639	0.185185185185185	1.53475618793538	0.109640595467644	0.540929938517565
GO:0001094	TFIID-class transcription factor complex binding	3/2249	10/18639	0.3	2.48630502445531	0.110033885009008	0.540929938517565
GO:0003680	minor groove of adenine-thymine-rich DNA binding	3/2249	10/18639	0.3	2.48630502445531	0.110033885009008	0.540929938517565
GO:0004382	GDP phosphatase activity	3/2249	10/18639	0.3	2.48630502445531	0.110033885009008	0.540929938517565
GO:0004935	adrenergic receptor activity	3/2249	10/18639	0.3	2.48630502445531	0.110033885009008	0.540929938517565
GO:0005337	nucleoside transmembrane transporter activity	3/2249	10/18639	0.3	2.48630502445531	0.110033885009008	0.540929938517565
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	3/2249	10/18639	0.3	2.48630502445531	0.110033885009008	0.540929938517565
GO:0030957	Tat protein binding	3/2249	10/18639	0.3	2.48630502445531	0.110033885009008	0.540929938517565
GO:0031720	haptoglobin binding	3/2249	10/18639	0.3	2.48630502445531	0.110033885009008	0.540929938517565
GO:0031996	thioesterase binding	3/2249	10/18639	0.3	2.48630502445531	0.110033885009008	0.540929938517565
GO:0032395	MHC class II receptor activity	3/2249	10/18639	0.3	2.48630502445531	0.110033885009008	0.540929938517565
GO:0042975	peroxisome proliferator activated receptor binding	3/2249	10/18639	0.3	2.48630502445531	0.110033885009008	0.540929938517565
GO:0070513	death domain binding	3/2249	10/18639	0.3	2.48630502445531	0.110033885009008	0.540929938517565
GO:0005178	integrin binding	25/2249	161/18639	0.15527950310559	1.28690736255451	0.111168691254054	0.544430700894381
GO:0005548	phospholipid transporter activity	12/2249	68/18639	0.176470588235294	1.46253236732666	0.112729170476896	0.549981710508491
GO:0015175	neutral L-amino acid transmembrane transporter activity	8/2249	41/18639	0.195121951219512	1.61710895899533	0.113871575493845	0.551378155022829
GO:0061650	ubiquitin-like protein conjugating enzyme activity	8/2249	41/18639	0.195121951219512	1.61710895899533	0.113871575493845	0.551378155022829
GO:0061135	endopeptidase regulator activity	28/2249	184/18639	0.152173913043478	1.26116921530342	0.116063690917296	0.554338910413244
GO:0015377	chloride:monoatomic cation symporter activity	5/2249	22/18639	0.227272727272727	1.88356441246615	0.117202443128677	0.554338910413244
GO:0140693	molecular condensate scaffold activity	9/2249	48/18639	0.1875	1.55394064028457	0.117840850932915	0.554338910413244
GO:0015378	sodium:chloride symporter activity	4/2249	16/18639	0.25	2.07192085371276	0.117926134668656	0.554338910413244
GO:0016722	oxidoreductase activity, acting on metal ions	4/2249	16/18639	0.25	2.07192085371276	0.117926134668656	0.554338910413244
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/2249	16/18639	0.25	2.07192085371276	0.117926134668656	0.554338910413244
GO:0097027	ubiquitin-protein transferase activator activity	4/2249	16/18639	0.25	2.07192085371276	0.117926134668656	0.554338910413244
GO:0140328	floppase activity	4/2249	16/18639	0.25	2.07192085371276	0.117926134668656	0.554338910413244
GO:0001540	amyloid-beta binding	14/2249	83/18639	0.168674698795181	1.39792250370981	0.121864366744051	0.570727881949798
GO:0008080	N-acetyltransferase activity	12/2249	69/18639	0.173913043478261	1.44133624606105	0.122298831846385	0.570727881949798
GO:0140375	immune receptor activity	24/2249	156/18639	0.153846153846154	1.27502821766939	0.125748209018885	0.584541813547257
GO:0031492	nucleosomal DNA binding	8/2249	42/18639	0.19047619047619	1.57860636473353	0.126620470481122	0.584541813547257
GO:0048487	beta-tubulin binding	8/2249	42/18639	0.19047619047619	1.57860636473353	0.126620470481122	0.584541813547257
GO:0004725	protein tyrosine phosphatase activity	16/2249	98/18639	0.163265306122449	1.3530911697716	0.128257408851694	0.586693314291683
GO:0008514	organic anion transmembrane transporter activity	39/2249	269/18639	0.144981412639405	1.20156004899327	0.128452524206004	0.586693314291683
GO:0004629	phospholipase C activity	6/2249	29/18639	0.206896551724138	1.71469312031401	0.128908546540797	0.586693314291683
GO:0106222	lncRNA binding	6/2249	29/18639	0.206896551724138	1.71469312031401	0.128908546540797	0.586693314291683
GO:0001222	transcription corepressor binding	9/2249	49/18639	0.183673469387755	1.52222756599305	0.129777387180365	0.58856786862081
GO:0003724	RNA helicase activity	13/2249	77/18639	0.168831168831169	1.39921927783199	0.131805952963142	0.592053346185608
GO:0004602	glutathione peroxidase activity	5/2249	23/18639	0.217391304347826	1.80167030757631	0.13568543283363	0.592053346185608
GO:0005158	insulin receptor binding	5/2249	23/18639	0.217391304347826	1.80167030757631	0.13568543283363	0.592053346185608
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	3/2249	11/18639	0.272727272727273	2.26027729495938	0.138290751472251	0.592053346185608
GO:0004523	RNA-DNA hybrid ribonuclease activity	3/2249	11/18639	0.272727272727273	2.26027729495938	0.138290751472251	0.592053346185608
GO:0005114	type II transforming growth factor beta receptor binding	3/2249	11/18639	0.272727272727273	2.26027729495938	0.138290751472251	0.592053346185608
GO:0008526	phosphatidylinositol transfer activity	3/2249	11/18639	0.272727272727273	2.26027729495938	0.138290751472251	0.592053346185608
GO:0015217	ADP transmembrane transporter activity	3/2249	11/18639	0.272727272727273	2.26027729495938	0.138290751472251	0.592053346185608
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	3/2249	11/18639	0.272727272727273	2.26027729495938	0.138290751472251	0.592053346185608
GO:0034713	type I transforming growth factor beta receptor binding	3/2249	11/18639	0.272727272727273	2.26027729495938	0.138290751472251	0.592053346185608
GO:0043522	leucine zipper domain binding	3/2249	11/18639	0.272727272727273	2.26027729495938	0.138290751472251	0.592053346185608
GO:0050786	RAGE receptor binding	3/2249	11/18639	0.272727272727273	2.26027729495938	0.138290751472251	0.592053346185608
GO:0046943	carboxylic acid transmembrane transporter activity	28/2249	188/18639	0.148936170212766	1.23433582774377	0.139959702841394	0.592053346185608
GO:0048156	tau protein binding	8/2249	43/18639	0.186046511627907	1.5418945888095	0.140075603658207	0.592053346185608
GO:0004549	tRNA-specific ribonuclease activity	4/2249	17/18639	0.235294117647059	1.95004315643554	0.14023261826488	0.592053346185608
GO:0015278	intracellularly gated calcium channel activity	4/2249	17/18639	0.235294117647059	1.95004315643554	0.14023261826488	0.592053346185608
GO:0032183	SUMO binding	4/2249	17/18639	0.235294117647059	1.95004315643554	0.14023261826488	0.592053346185608
GO:0038191	neuropilin binding	4/2249	17/18639	0.235294117647059	1.95004315643554	0.14023261826488	0.592053346185608
GO:0046965	nuclear retinoid X receptor binding	4/2249	17/18639	0.235294117647059	1.95004315643554	0.14023261826488	0.592053346185608
GO:0070403	NAD+ binding	4/2249	17/18639	0.235294117647059	1.95004315643554	0.14023261826488	0.592053346185608
GO:0019838	growth factor binding	21/2249	136/18639	0.154411764705882	1.27971582141082	0.140658636593786	0.592053346185608
GO:0044325	transmembrane transporter binding	21/2249	136/18639	0.154411764705882	1.27971582141082	0.140658636593786	0.592053346185608
GO:0015605	organophosphate ester transmembrane transporter activity	9/2249	50/18639	0.18	1.49178301467319	0.142324069785286	0.597112058252273
GO:0019888	protein phosphatase regulator activity	17/2249	107/18639	0.158878504672897	1.3167347481539	0.143269368125558	0.599126448525061
GO:0008106	alcohol dehydrogenase (NADP+) activity	6/2249	30/18639	0.2	1.65753668297021	0.145647584538985	0.601279992733312
GO:0015215	nucleotide transmembrane transporter activity	6/2249	30/18639	0.2	1.65753668297021	0.145647584538985	0.601279992733312
GO:0005342	organic acid transmembrane transporter activity	28/2249	189/18639	0.148148148148148	1.2278049503483	0.146358638795216	0.601279992733312
GO:0005539	glycosaminoglycan binding	35/2249	242/18639	0.144628099173554	1.19863189884209	0.146567097465775	0.601279992733312
GO:0016874	ligase activity	25/2249	167/18639	0.149700598802395	1.24067116988788	0.149819876297488	0.601279992733312
GO:0022829	wide pore channel activity	7/2249	37/18639	0.189189189189189	1.56794010551236	0.151253263133765	0.601279992733312
GO:0016298	lipase activity	20/2249	130/18639	0.153846153846154	1.27502821766939	0.151416779011043	0.601279992733312
GO:0016798	hydrolase activity, acting on glycosyl bonds	20/2249	130/18639	0.153846153846154	1.27502821766939	0.151416779011043	0.601279992733312
GO:0008186	ATP-dependent activity, acting on RNA	13/2249	79/18639	0.164556962025316	1.36379600497549	0.151993486582465	0.601279992733312
GO:0046332	SMAD binding	13/2249	79/18639	0.164556962025316	1.36379600497549	0.151993486582465	0.601279992733312
GO:0005518	collagen binding	12/2249	72/18639	0.166666666666667	1.38128056914184	0.153635709828238	0.601279992733312
GO:0019205	nucleobase-containing compound kinase activity	8/2249	44/18639	0.181818181818182	1.50685152997292	0.154210250645886	0.601279992733312
GO:0001091	RNA polymerase II general transcription initiation factor binding	5/2249	24/18639	0.208333333333333	1.7266007114273	0.155362565892171	0.601279992733312
GO:0004622	lysophospholipase activity	5/2249	24/18639	0.208333333333333	1.7266007114273	0.155362565892171	0.601279992733312
GO:0005315	phosphate transmembrane transporter activity	5/2249	24/18639	0.208333333333333	1.7266007114273	0.155362565892171	0.601279992733312
GO:0015295	solute:proton symporter activity	5/2249	24/18639	0.208333333333333	1.7266007114273	0.155362565892171	0.601279992733312
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	5/2249	24/18639	0.208333333333333	1.7266007114273	0.155362565892171	0.601279992733312
GO:0050431	transforming growth factor beta binding	5/2249	24/18639	0.208333333333333	1.7266007114273	0.155362565892171	0.601279992733312
GO:0005048	signal sequence binding	9/2249	51/18639	0.176470588235294	1.46253236732666	0.155460724713562	0.601279992733312
GO:0016830	carbon-carbon lyase activity	9/2249	51/18639	0.176470588235294	1.46253236732666	0.155460724713562	0.601279992733312
GO:0015294	solute:monoatomic cation symporter activity	18/2249	116/18639	0.155172413793103	1.28601984023551	0.157815004507963	0.601279992733312
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	33/2249	229/18639	0.14410480349345	1.19429498991303	0.159854902085227	0.601279992733312
GO:0008327	methyl-CpG binding	6/2249	31/18639	0.193548387096774	1.60406775771311	0.163313300861949	0.601279992733312
GO:0047499	calcium-independent phospholipase A2 activity	6/2249	31/18639	0.193548387096774	1.60406775771311	0.163313300861949	0.601279992733312
GO:0070325	lipoprotein particle receptor binding	6/2249	31/18639	0.193548387096774	1.60406775771311	0.163313300861949	0.601279992733312
GO:0072349	modified amino acid transmembrane transporter activity	6/2249	31/18639	0.193548387096774	1.60406775771311	0.163313300861949	0.601279992733312
GO:0000400	four-way junction DNA binding	4/2249	18/18639	0.222222222222222	1.84170742552245	0.164053620273033	0.601279992733312
GO:0000900	mRNA regulatory element binding translation repressor activity	4/2249	18/18639	0.222222222222222	1.84170742552245	0.164053620273033	0.601279992733312
GO:0015373	monoatomic anion:sodium symporter activity	4/2249	18/18639	0.222222222222222	1.84170742552245	0.164053620273033	0.601279992733312
GO:0017128	phospholipid scramblase activity	4/2249	18/18639	0.222222222222222	1.84170742552245	0.164053620273033	0.601279992733312
GO:1990381	ubiquitin-specific protease binding	4/2249	18/18639	0.222222222222222	1.84170742552245	0.164053620273033	0.601279992733312
GO:0008238	exopeptidase activity	16/2249	102/18639	0.156862745098039	1.30002877095703	0.164275822634187	0.601279992733312
GO:0043539	protein serine/threonine kinase activator activity	12/2249	73/18639	0.164383561643836	1.36235891750976	0.164925099599571	0.601279992733312
GO:0019208	phosphatase regulator activity	18/2249	117/18639	0.153846153846154	1.27502821766939	0.166711798245823	0.601279992733312
GO:0042887	amide transmembrane transporter activity	7/2249	38/18639	0.184210526315789	1.52667852378835	0.167330085897688	0.601279992733312
GO:0031593	polyubiquitin modification-dependent protein binding	10/2249	59/18639	0.169491525423729	1.40469210421204	0.168349300697226	0.601279992733312
GO:0003995	acyl-CoA dehydrogenase activity	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0004300	enoyl-CoA hydratase activity	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0004526	ribonuclease P activity	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0004875	complement receptor activity	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0008504	monoamine transmembrane transporter activity	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0010853	cyclase activator activity	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0015132	prostaglandin transmembrane transporter activity	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0016208	AMP binding	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0016801	hydrolase activity, acting on ether bonds	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0016803	ether hydrolase activity	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0031543	peptidyl-proline dioxygenase activity	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0035259	nuclear glucocorticoid receptor binding	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0042301	phosphate ion binding	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0043047	single-stranded telomeric DNA binding	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/2249	12/18639	0.25	2.07192085371276	0.168662854700422	0.601279992733312
GO:0046915	transition metal ion transmembrane transporter activity	8/2249	45/18639	0.177777777777778	1.47336594041796	0.16899328988312	0.601279992733312
GO:0140303	intramembrane lipid transporter activity	8/2249	45/18639	0.177777777777778	1.47336594041796	0.16899328988312	0.601279992733312
GO:0005319	lipid transporter activity	26/2249	178/18639	0.146067415730337	1.21056049879847	0.174957675952706	0.616450380045956
GO:0015296	monoatomic anion:monoatomic cation symporter activity	5/2249	25/18639	0.2	1.65753668297021	0.17612868001313	0.616450380045956
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	5/2249	25/18639	0.2	1.65753668297021	0.17612868001313	0.616450380045956
GO:0042974	nuclear retinoic acid receptor binding	5/2249	25/18639	0.2	1.65753668297021	0.17612868001313	0.616450380045956
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	5/2249	25/18639	0.2	1.65753668297021	0.17612868001313	0.616450380045956
GO:0120020	cholesterol transfer activity	5/2249	25/18639	0.2	1.65753668297021	0.17612868001313	0.616450380045956
GO:0004896	cytokine receptor activity	15/2249	96/18639	0.15625	1.29495053357048	0.17773556543005	0.620388640308683
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	14/2249	89/18639	0.157303370786517	1.30368053716758	0.181436134621525	0.622889643698472
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	14/2249	89/18639	0.157303370786517	1.30368053716758	0.181436134621525	0.622889643698472
GO:0001098	basal transcription machinery binding	10/2249	60/18639	0.166666666666667	1.38128056914184	0.181615994893414	0.622889643698472
GO:0001099	basal RNA polymerase II transcription machinery binding	10/2249	60/18639	0.166666666666667	1.38128056914184	0.181615994893414	0.622889643698472
GO:0004714	transmembrane receptor protein tyrosine kinase activity	10/2249	60/18639	0.166666666666667	1.38128056914184	0.181615994893414	0.622889643698472
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	10/2249	60/18639	0.166666666666667	1.38128056914184	0.181615994893414	0.622889643698472
GO:0047498	calcium-dependent phospholipase A2 activity	6/2249	32/18639	0.1875	1.55394064028457	0.18183734940266	0.622889643698472
GO:0004864	protein phosphatase inhibitor activity	9/2249	53/18639	0.169811320754717	1.40734246667282	0.183406696757835	0.624941337100773
GO:0034212	protein N-acetyltransferase activity	9/2249	53/18639	0.169811320754717	1.40734246667282	0.183406696757835	0.624941337100773
GO:0019003	GDP binding	12/2249	75/18639	0.16	1.32602934637617	0.188693225421297	0.627110717509178
GO:0005346	purine ribonucleotide transmembrane transporter activity	4/2249	19/18639	0.210526315789474	1.74477545575811	0.189192510486372	0.627110717509178
GO:0008381	mechanosensitive monoatomic ion channel activity	4/2249	19/18639	0.210526315789474	1.74477545575811	0.189192510486372	0.627110717509178
GO:0008574	plus-end-directed microtubule motor activity	4/2249	19/18639	0.210526315789474	1.74477545575811	0.189192510486372	0.627110717509178
GO:0015245	fatty acid transmembrane transporter activity	4/2249	19/18639	0.210526315789474	1.74477545575811	0.189192510486372	0.627110717509178
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	4/2249	19/18639	0.210526315789474	1.74477545575811	0.189192510486372	0.627110717509178
GO:0046624	sphingolipid transporter activity	4/2249	19/18639	0.210526315789474	1.74477545575811	0.189192510486372	0.627110717509178
GO:0050145	nucleoside monophosphate kinase activity	4/2249	19/18639	0.210526315789474	1.74477545575811	0.189192510486372	0.627110717509178
GO:0003777	microtubule motor activity	11/2249	68/18639	0.161764705882353	1.34065467004943	0.192138545496017	0.627110717509178
GO:0140793	histone H2AXY142 phosphatase activity	14/2249	90/18639	0.155555555555556	1.28919519786572	0.192554249459229	0.627110717509178
GO:0015026	coreceptor activity	10/2249	61/18639	0.163934426229508	1.35863662538542	0.195342927778784	0.627110717509178
GO:0005160	transforming growth factor beta receptor binding	5/2249	26/18639	0.192307692307692	1.59378527208674	0.197869950546836	0.627110717509178
GO:0008143	poly(A) binding	5/2249	26/18639	0.192307692307692	1.59378527208674	0.197869950546836	0.627110717509178
GO:0008157	protein phosphatase 1 binding	5/2249	26/18639	0.192307692307692	1.59378527208674	0.197869950546836	0.627110717509178
GO:0070412	R-SMAD binding	5/2249	26/18639	0.192307692307692	1.59378527208674	0.197869950546836	0.627110717509178
GO:0042626	ATPase-coupled transmembrane transporter activity	15/2249	98/18639	0.153061224489796	1.26852297166087	0.19914022147808	0.627110717509178
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	19/2249	128/18639	0.1484375	1.23020300689195	0.199594814961641	0.627110717509178
GO:0061733	protein-lysine-acetyltransferase activity	8/2249	47/18639	0.170212765957447	1.41066951742145	0.200360613455726	0.627110717509178
GO:0061749	forked DNA-dependent helicase activity	8/2249	47/18639	0.170212765957447	1.41066951742145	0.200360613455726	0.627110717509178
GO:1990518	single-stranded 3'-5' DNA helicase activity	8/2249	47/18639	0.170212765957447	1.41066951742145	0.200360613455726	0.627110717509178
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/2249	13/18639	0.230769230769231	1.91254232650409	0.200714742152873	0.627110717509178
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/2249	13/18639	0.230769230769231	1.91254232650409	0.200714742152873	0.627110717509178
GO:0019104	DNA N-glycosylase activity	3/2249	13/18639	0.230769230769231	1.91254232650409	0.200714742152873	0.627110717509178
GO:0035325	Toll-like receptor binding	3/2249	13/18639	0.230769230769231	1.91254232650409	0.200714742152873	0.627110717509178
GO:0043560	insulin receptor substrate binding	3/2249	13/18639	0.230769230769231	1.91254232650409	0.200714742152873	0.627110717509178
GO:0046974	histone H3K9 methyltransferase activity	3/2249	13/18639	0.230769230769231	1.91254232650409	0.200714742152873	0.627110717509178
GO:0051011	microtubule minus-end binding	3/2249	13/18639	0.230769230769231	1.91254232650409	0.200714742152873	0.627110717509178
GO:0061459	L-arginine transmembrane transporter activity	3/2249	13/18639	0.230769230769231	1.91254232650409	0.200714742152873	0.627110717509178
GO:0071714	icosanoid transmembrane transporter activity	3/2249	13/18639	0.230769230769231	1.91254232650409	0.200714742152873	0.627110717509178
GO:0089720	caspase binding	3/2249	13/18639	0.230769230769231	1.91254232650409	0.200714742152873	0.627110717509178
GO:0140666	annealing activity	3/2249	13/18639	0.230769230769231	1.91254232650409	0.200714742152873	0.627110717509178
GO:1901338	catecholamine binding	3/2249	13/18639	0.230769230769231	1.91254232650409	0.200714742152873	0.627110717509178
GO:0098631	cell adhesion mediator activity	12/2249	76/18639	0.157894736842105	1.30858159181859	0.201140899596351	0.627110717509178
GO:0019956	chemokine binding	6/2249	33/18639	0.181818181818182	1.50685152997292	0.201145258155133	0.627110717509178
GO:0071889	14-3-3 protein binding	6/2249	33/18639	0.181818181818182	1.50685152997292	0.201145258155133	0.627110717509178
GO:0050997	quaternary ammonium group binding	7/2249	40/18639	0.175	1.45034459759893	0.201571302056522	0.627110717509178
GO:0072341	modified amino acid binding	14/2249	91/18639	0.153846153846154	1.27502821766939	0.203983635362069	0.633086559870709
GO:1901681	sulfur compound binding	38/2249	275/18639	0.138181818181818	1.14520716277942	0.20792082309001	0.643754856105607
GO:0004527	exonuclease activity	13/2249	84/18639	0.154761904761905	1.282617671346	0.208923373205758	0.645307685105555
GO:0015179	L-amino acid transmembrane transporter activity	10/2249	62/18639	0.161290322580645	1.33672313142759	0.209504990579757	0.645556047528055
GO:0005525	GTP binding	51/2249	378/18639	0.134920634920635	1.11817950835292	0.215401708687861	0.654148854699884
GO:0000339	RNA cap binding	4/2249	20/18639	0.2	1.65753668297021	0.215445656356489	0.654148854699884
GO:0015095	magnesium ion transmembrane transporter activity	4/2249	20/18639	0.2	1.65753668297021	0.215445656356489	0.654148854699884
GO:0030742	GTP-dependent protein binding	4/2249	20/18639	0.2	1.65753668297021	0.215445656356489	0.654148854699884
GO:0003924	GTPase activity	45/2249	331/18639	0.13595166163142	1.12672433132416	0.216234853115901	0.654148854699884
GO:0009378	four-way junction helicase activity	8/2249	48/18639	0.166666666666667	1.38128056914184	0.216864565960288	0.654148854699884
GO:0016879	ligase activity, forming carbon-nitrogen bonds	8/2249	48/18639	0.166666666666667	1.38128056914184	0.216864565960288	0.654148854699884
GO:0036121	double-stranded DNA helicase activity	8/2249	48/18639	0.166666666666667	1.38128056914184	0.216864565960288	0.654148854699884
GO:0043138	3'-5' DNA helicase activity	8/2249	48/18639	0.166666666666667	1.38128056914184	0.216864565960288	0.654148854699884
GO:0005085	guanyl-nucleotide exchange factor activity	32/2249	230/18639	0.139130434782609	1.15306899684884	0.219439855791986	0.660370407149716
GO:0035255	ionotropic glutamate receptor binding	5/2249	27/18639	0.185185185185185	1.53475618793538	0.22046646005271	0.661913287990421
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	6/2249	34/18639	0.176470588235294	1.46253236732666	0.22115774502621	0.66244459440409
GO:0005507	copper ion binding	10/2249	63/18639	0.158730158730159	1.31550530394461	0.224075195049094	0.669626104926294
GO:0019212	phosphatase inhibitor activity	9/2249	56/18639	0.160714285714286	1.33194912024392	0.22906728048254	0.681382580280627
GO:0170055	lipid transmembrane transporter activity	9/2249	56/18639	0.160714285714286	1.33194912024392	0.22906728048254	0.681382580280627
GO:0030295	protein kinase activator activity	20/2249	139/18639	0.143884892086331	1.19247243379152	0.232931525975682	0.689762547334943
GO:0005344	oxygen carrier activity	3/2249	14/18639	0.214285714285714	1.77593216032522	0.23402657856007	0.689762547334943
GO:0005347	ATP transmembrane transporter activity	3/2249	14/18639	0.214285714285714	1.77593216032522	0.23402657856007	0.689762547334943
GO:1990825	sequence-specific mRNA binding	3/2249	14/18639	0.214285714285714	1.77593216032522	0.23402657856007	0.689762547334943
GO:0004402	histone acetyltransferase activity	7/2249	42/18639	0.166666666666667	1.38128056914184	0.238228459640027	0.694204199132025
GO:0004520	DNA endonuclease activity	7/2249	42/18639	0.166666666666667	1.38128056914184	0.238228459640027	0.694204199132025
GO:0019894	kinesin binding	7/2249	42/18639	0.166666666666667	1.38128056914184	0.238228459640027	0.694204199132025
GO:0043175	RNA polymerase core enzyme binding	7/2249	42/18639	0.166666666666667	1.38128056914184	0.238228459640027	0.694204199132025
GO:0051879	Hsp90 protein binding	7/2249	42/18639	0.166666666666667	1.38128056914184	0.238228459640027	0.694204199132025
GO:0004623	phospholipase A2 activity	6/2249	35/18639	0.171428571428571	1.42074572826018	0.241791995267201	0.700854480409161
GO:0061631	ubiquitin conjugating enzyme activity	6/2249	35/18639	0.171428571428571	1.42074572826018	0.241791995267201	0.700854480409161
GO:0010314	phosphatidylinositol-5-phosphate binding	4/2249	21/18639	0.19047619047619	1.57860636473353	0.242607601016265	0.700854480409161
GO:1990782	protein tyrosine kinase binding	17/2249	117/18639	0.145299145299145	1.20419331668776	0.242687188091992	0.700854480409161
GO:0019209	kinase activator activity	21/2249	148/18639	0.141891891891892	1.17595507913427	0.24608241291203	0.709069681947863
GO:0031406	carboxylic acid binding	26/2249	187/18639	0.13903743315508	1.15229822880282	0.248806174036857	0.709515953314995
GO:0004222	metalloendopeptidase activity	16/2249	110/18639	0.145454545454545	1.20548122397833	0.249856500140229	0.709515953314995
GO:0005006	epidermal growth factor receptor activity	8/2249	50/18639	0.16	1.32602934637617	0.251292065529028	0.709515953314995
GO:0005017	platelet-derived growth factor receptor activity	8/2249	50/18639	0.16	1.32602934637617	0.251292065529028	0.709515953314995
GO:0005019	platelet-derived growth factor beta-receptor activity	8/2249	50/18639	0.16	1.32602934637617	0.251292065529028	0.709515953314995
GO:0032813	tumor necrosis factor receptor superfamily binding	8/2249	50/18639	0.16	1.32602934637617	0.251292065529028	0.709515953314995
GO:0019001	guanyl nucleotide binding	53/2249	400/18639	0.1325	1.09811805246776	0.252097703432682	0.709515953314995
GO:0032561	guanyl ribonucleotide binding	53/2249	400/18639	0.1325	1.09811805246776	0.252097703432682	0.709515953314995
GO:0000049	tRNA binding	12/2249	80/18639	0.15	1.24315251222766	0.254262408964912	0.709515953314995
GO:0004712	protein serine/threonine/tyrosine kinase activity	7/2249	43/18639	0.162790697674419	1.34915776520831	0.257313737192048	0.709515953314995
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	7/2249	43/18639	0.162790697674419	1.34915776520831	0.257313737192048	0.709515953314995
GO:0008408	3'-5' exonuclease activity	9/2249	58/18639	0.155172413793103	1.28601984023551	0.261605648368668	0.709515953314995
GO:0000993	RNA polymerase II complex binding	6/2249	36/18639	0.166666666666667	1.38128056914184	0.262962879461908	0.709515953314995
GO:0004033	aldo-keto reductase (NADPH) activity	6/2249	36/18639	0.166666666666667	1.38128056914184	0.262962879461908	0.709515953314995
GO:0020037	heme binding	20/2249	142/18639	0.140845070422535	1.16727935420437	0.263692746019039	0.709515953314995
GO:0043177	organic acid binding	26/2249	189/18639	0.137566137566138	1.140104596752	0.266817635172533	0.709515953314995
GO:0099604	ligand-gated calcium channel activity	5/2249	29/18639	0.172413793103448	1.42891093359501	0.267729178067664	0.709515953314995
GO:0000774	adenyl-nucleotide exchange factor activity	3/2249	15/18639	0.2	1.65753668297021	0.268203777482614	0.709515953314995
GO:0004559	alpha-mannosidase activity	3/2249	15/18639	0.2	1.65753668297021	0.268203777482614	0.709515953314995
GO:0004865	protein serine/threonine phosphatase inhibitor activity	3/2249	15/18639	0.2	1.65753668297021	0.268203777482614	0.709515953314995
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/2249	15/18639	0.2	1.65753668297021	0.268203777482614	0.709515953314995
GO:0015929	hexosaminidase activity	3/2249	15/18639	0.2	1.65753668297021	0.268203777482614	0.709515953314995
GO:0016846	carbon-sulfur lyase activity	3/2249	15/18639	0.2	1.65753668297021	0.268203777482614	0.709515953314995
GO:0047372	monoacylglycerol lipase activity	3/2249	15/18639	0.2	1.65753668297021	0.268203777482614	0.709515953314995
GO:0140161	monocarboxylate:sodium symporter activity	3/2249	15/18639	0.2	1.65753668297021	0.268203777482614	0.709515953314995
GO:0015101	organic cation transmembrane transporter activity	12/2249	81/18639	0.148148148148148	1.2278049503483	0.268272475150104	0.709515953314995
GO:0005021	vascular endothelial growth factor receptor activity	8/2249	51/18639	0.156862745098039	1.30002877095703	0.26912115219237	0.709515953314995
GO:0042578	phosphoric ester hydrolase activity	48/2249	363/18639	0.132231404958678	1.09589202179849	0.269396389881174	0.709515953314995
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	36/2249	268/18639	0.134328358208955	1.11327090647253	0.270174764051693	0.709515953314995
GO:0008649	rRNA methyltransferase activity	4/2249	22/18639	0.181818181818182	1.50685152997292	0.270475413880173	0.709515953314995
GO:0032931	histone H3K56 acetyltransferase activity	4/2249	22/18639	0.181818181818182	1.50685152997292	0.270475413880173	0.709515953314995
GO:0043992	histone H3K9 acetyltransferase activity	4/2249	22/18639	0.181818181818182	1.50685152997292	0.270475413880173	0.709515953314995
GO:0043993	histone H3K18 acetyltransferase activity	4/2249	22/18639	0.181818181818182	1.50685152997292	0.270475413880173	0.709515953314995
GO:0043994	histone H3K23 acetyltransferase activity	4/2249	22/18639	0.181818181818182	1.50685152997292	0.270475413880173	0.709515953314995
GO:0043999	histone H2AK5 acetyltransferase activity	4/2249	22/18639	0.181818181818182	1.50685152997292	0.270475413880173	0.709515953314995
GO:0044012	histone H2AK9 acetyltransferase activity	4/2249	22/18639	0.181818181818182	1.50685152997292	0.270475413880173	0.709515953314995
GO:0044014	histone H2BK5 acetyltransferase activity	4/2249	22/18639	0.181818181818182	1.50685152997292	0.270475413880173	0.709515953314995
GO:0044015	histone H2BK12 acetyltransferase activity	4/2249	22/18639	0.181818181818182	1.50685152997292	0.270475413880173	0.709515953314995
GO:0044016	histone H3K4 acetyltransferase activity	4/2249	22/18639	0.181818181818182	1.50685152997292	0.270475413880173	0.709515953314995
GO:0044017	histone H3K27 acetyltransferase activity	4/2249	22/18639	0.181818181818182	1.50685152997292	0.270475413880173	0.709515953314995
GO:0044018	histone H3K36 acetyltransferase activity	4/2249	22/18639	0.181818181818182	1.50685152997292	0.270475413880173	0.709515953314995
GO:0046972	histone H4K16 acetyltransferase activity	4/2249	22/18639	0.181818181818182	1.50685152997292	0.270475413880173	0.709515953314995
GO:0140784	metal ion sensor activity	4/2249	22/18639	0.181818181818182	1.50685152997292	0.270475413880173	0.709515953314995
GO:0140908	histone H3K122 acetyltransferase activity	4/2249	22/18639	0.181818181818182	1.50685152997292	0.270475413880173	0.709515953314995
GO:0003779	actin binding	58/2249	443/18639	0.130925507900677	1.08506916040939	0.271314918841786	0.710271576154921
GO:0048029	monosaccharide binding	11/2249	74/18639	0.148648648648649	1.23195294004543	0.276801845598153	0.721748796056705
GO:0030547	signaling receptor inhibitor activity	7/2249	44/18639	0.159090909090909	1.3184950887263	0.276819802214295	0.721748796056705
GO:0000287	magnesium ion binding	31/2249	230/18639	0.134782608695652	1.11703559069731	0.282012436236932	0.733802056309432
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	10/2249	67/18639	0.149253731343284	1.23696767385836	0.285844549647425	0.734677221787922
GO:0001217	DNA-binding transcription repressor activity	37/2249	278/18639	0.133093525179856	1.10303700125715	0.286297577036496	0.734677221787922
GO:0046906	tetrapyrrole binding	21/2249	152/18639	0.138157894736842	1.14500889284126	0.287117152027786	0.734677221787922
GO:0005080	protein kinase C binding	8/2249	52/18639	0.153846153846154	1.27502821766939	0.287295213737414	0.734677221787922
GO:0004540	RNA nuclease activity	17/2249	121/18639	0.140495867768595	1.16438527316089	0.288803868254585	0.734677221787922
GO:0033218	amide binding	33/2249	247/18639	0.133603238866397	1.10726134692342	0.2919911811616	0.734677221787922
GO:0031210	phosphatidylcholine binding	5/2249	30/18639	0.166666666666667	1.38128056914184	0.2921454967734	0.734677221787922
GO:0048019	receptor antagonist activity	5/2249	30/18639	0.166666666666667	1.38128056914184	0.2921454967734	0.734677221787922
GO:0051721	protein phosphatase 2A binding	5/2249	30/18639	0.166666666666667	1.38128056914184	0.2921454967734	0.734677221787922
GO:0008237	metallopeptidase activity	25/2249	184/18639	0.135869565217391	1.1260439422352	0.29353190962366	0.734677221787922
GO:0008013	beta-catenin binding	15/2249	106/18639	0.141509433962264	1.17278538889402	0.295036608143591	0.734677221787922
GO:0019787	ubiquitin-like protein transferase activity	62/2249	479/18639	0.129436325678497	1.07272728960494	0.295105070212579	0.734677221787922
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	9/2249	60/18639	0.15	1.24315251222766	0.295469872606488	0.734677221787922
GO:0016829	lyase activity	27/2249	200/18639	0.135	1.11883726100489	0.295831328555607	0.734677221787922
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	12/2249	83/18639	0.144578313253012	1.19821928889413	0.297011358159542	0.734677221787922
GO:0000295	adenine nucleotide transmembrane transporter activity	4/2249	23/18639	0.173913043478261	1.44133624606105	0.298852251995235	0.734677221787922
GO:0003887	DNA-directed DNA polymerase activity	4/2249	23/18639	0.173913043478261	1.44133624606105	0.298852251995235	0.734677221787922
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	4/2249	23/18639	0.173913043478261	1.44133624606105	0.298852251995235	0.734677221787922
GO:0031681	G-protein beta-subunit binding	4/2249	23/18639	0.173913043478261	1.44133624606105	0.298852251995235	0.734677221787922
GO:0044013	histone H2B acetyltransferase activity	4/2249	23/18639	0.173913043478261	1.44133624606105	0.298852251995235	0.734677221787922
GO:0070577	lysine-acetylated histone binding	4/2249	23/18639	0.173913043478261	1.44133624606105	0.298852251995235	0.734677221787922
GO:0140102	catalytic activity, acting on a rRNA	4/2249	23/18639	0.173913043478261	1.44133624606105	0.298852251995235	0.734677221787922
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	4/2249	23/18639	0.173913043478261	1.44133624606105	0.298852251995235	0.734677221787922
GO:0016755	aminoacyltransferase activity	64/2249	496/18639	0.129032258064516	1.06937850514207	0.300639296494393	0.734677221787922
GO:0030246	carbohydrate binding	37/2249	280/18639	0.132142857142857	1.09515816553389	0.301978653802398	0.734677221787922
GO:0030145	manganese ion binding	10/2249	68/18639	0.147058823529412	1.21877697277221	0.302000757259737	0.734677221787922
GO:0000062	fatty-acyl-CoA binding	3/2249	16/18639	0.1875	1.55394064028457	0.302883233516605	0.734677221787922
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/2249	16/18639	0.1875	1.55394064028457	0.302883233516605	0.734677221787922
GO:0005521	lamin binding	3/2249	16/18639	0.1875	1.55394064028457	0.302883233516605	0.734677221787922
GO:0008142	oxysterol binding	3/2249	16/18639	0.1875	1.55394064028457	0.302883233516605	0.734677221787922
GO:0015562	efflux transmembrane transporter activity	3/2249	16/18639	0.1875	1.55394064028457	0.302883233516605	0.734677221787922
GO:0015923	mannosidase activity	3/2249	16/18639	0.1875	1.55394064028457	0.302883233516605	0.734677221787922
GO:0022858	alanine transmembrane transporter activity	3/2249	16/18639	0.1875	1.55394064028457	0.302883233516605	0.734677221787922
GO:0030275	LRR domain binding	3/2249	16/18639	0.1875	1.55394064028457	0.302883233516605	0.734677221787922
GO:0055102	lipase inhibitor activity	3/2249	16/18639	0.1875	1.55394064028457	0.302883233516605	0.734677221787922
GO:0070411	I-SMAD binding	3/2249	16/18639	0.1875	1.55394064028457	0.302883233516605	0.734677221787922
GO:0005109	frizzled binding	6/2249	38/18639	0.157894736842105	1.30858159181859	0.306569222330619	0.741570385774261
GO:0016791	phosphatase activity	36/2249	273/18639	0.131868131868132	1.09288132943091	0.30971350798762	0.741570385774261
GO:0017147	Wnt-protein binding	5/2249	31/18639	0.161290322580645	1.33672313142759	0.316920919064064	0.741570385774261
GO:0070273	phosphatidylinositol-4-phosphate binding	5/2249	31/18639	0.161290322580645	1.33672313142759	0.316920919064064	0.741570385774261
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	8/2249	54/18639	0.148148148148148	1.2278049503483	0.324478086276029	0.741570385774261
GO:0050661	NADP binding	8/2249	54/18639	0.148148148148148	1.2278049503483	0.324478086276029	0.741570385774261
GO:0005540	hyaluronic acid binding	4/2249	24/18639	0.166666666666667	1.38128056914184	0.327550189215847	0.741570385774261
GO:0019957	C-C chemokine binding	4/2249	24/18639	0.166666666666667	1.38128056914184	0.327550189215847	0.741570385774261
GO:0043998	histone H2A acetyltransferase activity	4/2249	24/18639	0.166666666666667	1.38128056914184	0.327550189215847	0.741570385774261
GO:0070300	phosphatidic acid binding	4/2249	24/18639	0.166666666666667	1.38128056914184	0.327550189215847	0.741570385774261
GO:0140033	acetylation-dependent protein binding	4/2249	24/18639	0.166666666666667	1.38128056914184	0.327550189215847	0.741570385774261
GO:0016776	phosphotransferase activity, phosphate group as acceptor	6/2249	39/18639	0.153846153846154	1.27502821766939	0.328832676336219	0.741570385774261
GO:0061659	ubiquitin-like protein ligase activity	48/2249	372/18639	0.129032258064516	1.06937850514207	0.331322166949793	0.741570385774261
GO:0008028	monocarboxylic acid transmembrane transporter activity	10/2249	70/18639	0.142857142857143	1.18395477355015	0.33493795658518	0.741570385774261
GO:0016782	transferase activity, transferring sulphur-containing groups	10/2249	70/18639	0.142857142857143	1.18395477355015	0.33493795658518	0.741570385774261
GO:0005504	fatty acid binding	7/2249	47/18639	0.148936170212766	1.23433582774377	0.337221222271435	0.741570385774261
GO:0140359	ABC-type transporter activity	7/2249	47/18639	0.148936170212766	1.23433582774377	0.337221222271435	0.741570385774261
GO:0004550	nucleoside diphosphate kinase activity	3/2249	17/18639	0.176470588235294	1.46253236732666	0.337736936784832	0.741570385774261
GO:0004659	prenyltransferase activity	3/2249	17/18639	0.176470588235294	1.46253236732666	0.337736936784832	0.741570385774261
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/2249	17/18639	0.176470588235294	1.46253236732666	0.337736936784832	0.741570385774261
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	3/2249	17/18639	0.176470588235294	1.46253236732666	0.337736936784832	0.741570385774261
GO:0005092	GDP-dissociation inhibitor activity	3/2249	17/18639	0.176470588235294	1.46253236732666	0.337736936784832	0.741570385774261
GO:0015347	sodium-independent organic anion transmembrane transporter activity	3/2249	17/18639	0.176470588235294	1.46253236732666	0.337736936784832	0.741570385774261
GO:0016018	cyclosporin A binding	3/2249	17/18639	0.176470588235294	1.46253236732666	0.337736936784832	0.741570385774261
GO:0017110	nucleoside diphosphate phosphatase activity	3/2249	17/18639	0.176470588235294	1.46253236732666	0.337736936784832	0.741570385774261
GO:0019198	transmembrane receptor protein phosphatase activity	3/2249	17/18639	0.176470588235294	1.46253236732666	0.337736936784832	0.741570385774261
GO:0032977	membrane insertase activity	3/2249	17/18639	0.176470588235294	1.46253236732666	0.337736936784832	0.741570385774261
GO:0036041	long-chain fatty acid binding	3/2249	17/18639	0.176470588235294	1.46253236732666	0.337736936784832	0.741570385774261
GO:0051787	misfolded protein binding	3/2249	17/18639	0.176470588235294	1.46253236732666	0.337736936784832	0.741570385774261
GO:0070402	NADPH binding	3/2249	17/18639	0.176470588235294	1.46253236732666	0.337736936784832	0.741570385774261
GO:1901567	fatty acid derivative binding	3/2249	17/18639	0.176470588235294	1.46253236732666	0.337736936784832	0.741570385774261
GO:0008378	galactosyltransferase activity	5/2249	32/18639	0.15625	1.29495053357048	0.341936394927287	0.741570385774261
GO:0022884	macromolecule transmembrane transporter activity	5/2249	32/18639	0.15625	1.29495053357048	0.341936394927287	0.741570385774261
GO:0030515	snoRNA binding	5/2249	32/18639	0.15625	1.29495053357048	0.341936394927287	0.741570385774261
GO:0031369	translation initiation factor binding	5/2249	32/18639	0.15625	1.29495053357048	0.341936394927287	0.741570385774261
GO:0070717	poly-purine tract binding	5/2249	32/18639	0.15625	1.29495053357048	0.341936394927287	0.741570385774261
GO:0120015	sterol transfer activity	5/2249	32/18639	0.15625	1.29495053357048	0.341936394927287	0.741570385774261
GO:0140030	modification-dependent protein binding	23/2249	173/18639	0.132947976878613	1.10183074301488	0.342410779685593	0.741570385774261
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0004955	prostaglandin receptor activity	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0008140	cAMP response element binding protein binding	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0008190	eukaryotic initiation factor 4E binding	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0008239	dipeptidyl-peptidase activity	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0015643	toxic substance binding	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0019911	structural constituent of myelin sheath	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0031434	mitogen-activated protein kinase kinase binding	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0032356	oxidized DNA binding	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0033204	ribonuclease P RNA binding	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0035374	chondroitin sulfate binding	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0043121	neurotrophin binding	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0043422	protein kinase B binding	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0050308	sugar-phosphatase activity	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0051880	G-quadruplex DNA binding	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0097177	mitochondrial ribosome binding	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0098505	G-rich strand telomeric DNA binding	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0099122	RNA polymerase II C-terminal domain binding	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0140940	histone H2A methyltransferase activity	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:0141109	transporter activator activity	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:1990259	histone H2AQ104 methyltransferase activity	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:1990757	ubiquitin ligase activator activity	2/2249	10/18639	0.2	1.65753668297021	0.344300536252336	0.741570385774261
GO:1901682	sulfur compound transmembrane transporter activity	9/2249	63/18639	0.142857142857143	1.18395477355015	0.348050940057188	0.748396679121299
GO:0015370	solute:sodium symporter activity	11/2249	79/18639	0.139240506329114	1.15398123497926	0.354468421391396	0.758948140622787
GO:0003707	nuclear steroid receptor activity	4/2249	25/18639	0.16	1.32602934637617	0.356392381444937	0.758948140622787
GO:0005537	D-mannose binding	4/2249	25/18639	0.16	1.32602934637617	0.356392381444937	0.758948140622787
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	4/2249	25/18639	0.16	1.32602934637617	0.356392381444937	0.758948140622787
GO:0008081	phosphoric diester hydrolase activity	12/2249	87/18639	0.137931034482759	1.14312874687601	0.356691429934994	0.758948140622787
GO:0015291	secondary active transmembrane transporter activity	37/2249	287/18639	0.128919860627178	1.06844699076477	0.358971452912568	0.758948140622787
GO:0004519	endonuclease activity	17/2249	127/18639	0.133858267716535	1.10937494529502	0.362474721087795	0.758948140622787
GO:0004721	phosphoprotein phosphatase activity	23/2249	175/18639	0.131428571428571	1.08923839166614	0.363722134909078	0.758948140622787
GO:0004536	DNA nuclease activity	9/2249	64/18639	0.140625	1.16545548021343	0.365891565237352	0.758948140622787
GO:0004197	cysteine-type endopeptidase activity	12/2249	88/18639	0.136363636363636	1.13013864747969	0.371926923606927	0.758948140622787
GO:0008409	5'-3' exonuclease activity	3/2249	18/18639	0.166666666666667	1.38128056914184	0.372473600087191	0.758948140622787
GO:0035615	clathrin adaptor activity	3/2249	18/18639	0.166666666666667	1.38128056914184	0.372473600087191	0.758948140622787
GO:0050811	GABA receptor binding	3/2249	18/18639	0.166666666666667	1.38128056914184	0.372473600087191	0.758948140622787
GO:0070628	proteasome binding	3/2249	18/18639	0.166666666666667	1.38128056914184	0.372473600087191	0.758948140622787
GO:0016407	acetyltransferase activity	13/2249	96/18639	0.135416666666667	1.12229046242775	0.373041915136244	0.758948140622787
GO:0032182	ubiquitin-like protein binding	16/2249	120/18639	0.133333333333333	1.10502445531347	0.374859482765094	0.758948140622787
GO:0140789	histone phosphatase activity	18/2249	136/18639	0.132352941176471	1.09689927549499	0.375222783480543	0.758948140622787
GO:0005004	GPI-linked ephrin receptor activity	7/2249	49/18639	0.142857142857143	1.18395477355015	0.378422041937142	0.758948140622787
GO:0005008	hepatocyte growth factor receptor activity	7/2249	49/18639	0.142857142857143	1.18395477355015	0.378422041937142	0.758948140622787
GO:0005009	insulin receptor activity	7/2249	49/18639	0.142857142857143	1.18395477355015	0.378422041937142	0.758948140622787
GO:0005011	macrophage colony-stimulating factor receptor activity	7/2249	49/18639	0.142857142857143	1.18395477355015	0.378422041937142	0.758948140622787
GO:0005018	platelet-derived growth factor alpha-receptor activity	7/2249	49/18639	0.142857142857143	1.18395477355015	0.378422041937142	0.758948140622787
GO:0005020	stem cell factor receptor activity	7/2249	49/18639	0.142857142857143	1.18395477355015	0.378422041937142	0.758948140622787
GO:0008288	boss receptor activity	7/2249	49/18639	0.142857142857143	1.18395477355015	0.378422041937142	0.758948140622787
GO:0036332	placental growth factor receptor activity	7/2249	49/18639	0.142857142857143	1.18395477355015	0.378422041937142	0.758948140622787
GO:0038062	protein tyrosine kinase collagen receptor activity	7/2249	49/18639	0.142857142857143	1.18395477355015	0.378422041937142	0.758948140622787
GO:0060175	brain-derived neurotrophic factor receptor activity	7/2249	49/18639	0.142857142857143	1.18395477355015	0.378422041937142	0.758948140622787
GO:0004518	nuclease activity	27/2249	209/18639	0.129186602870813	1.07065766603339	0.382835127991625	0.758948140622787
GO:0051015	actin filament binding	27/2249	209/18639	0.129186602870813	1.07065766603339	0.382835127991625	0.758948140622787
GO:0120013	lipid transfer activity	9/2249	65/18639	0.138461538461538	1.14752539590245	0.383822062438228	0.758948140622787
GO:0001637	G protein-coupled chemoattractant receptor activity	4/2249	26/18639	0.153846153846154	1.27502821766939	0.385214641608228	0.758948140622787
GO:0004435	phosphatidylinositol phospholipase C activity	4/2249	26/18639	0.153846153846154	1.27502821766939	0.385214641608228	0.758948140622787
GO:0004529	DNA exonuclease activity	4/2249	26/18639	0.153846153846154	1.27502821766939	0.385214641608228	0.758948140622787
GO:0004950	chemokine receptor activity	4/2249	26/18639	0.153846153846154	1.27502821766939	0.385214641608228	0.758948140622787
GO:0015216	purine nucleotide transmembrane transporter activity	4/2249	26/18639	0.153846153846154	1.27502821766939	0.385214641608228	0.758948140622787
GO:0120014	phospholipid transfer activity	4/2249	26/18639	0.153846153846154	1.27502821766939	0.385214641608228	0.758948140622787
GO:0004521	RNA endonuclease activity	10/2249	73/18639	0.136986301369863	1.1352990979248	0.385399445090062	0.758948140622787
GO:0033192	calmodulin-dependent protein phosphatase activity	11/2249	81/18639	0.135802469135802	1.12548787115261	0.386498707161404	0.758948140622787
GO:0140791	histone H2AXS140 phosphatase activity	11/2249	81/18639	0.135802469135802	1.12548787115261	0.386498707161404	0.758948140622787
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	11/2249	81/18639	0.135802469135802	1.12548787115261	0.386498707161404	0.758948140622787
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	11/2249	81/18639	0.135802469135802	1.12548787115261	0.386498707161404	0.758948140622787
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	11/2249	81/18639	0.135802469135802	1.12548787115261	0.386498707161404	0.758948140622787
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	11/2249	81/18639	0.135802469135802	1.12548787115261	0.386498707161404	0.758948140622787
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	11/2249	81/18639	0.135802469135802	1.12548787115261	0.386498707161404	0.758948140622787
GO:1990439	MAP kinase serine/threonine phosphatase activity	11/2249	81/18639	0.135802469135802	1.12548787115261	0.386498707161404	0.758948140622787
GO:0035591	signaling adaptor activity	17/2249	129/18639	0.131782945736434	1.09217533374006	0.387800693578796	0.758948140622787
GO:0000099	sulfur amino acid transmembrane transporter activity	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0004954	prostanoid receptor activity	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0005225	volume-sensitive anion channel activity	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0008503	benzodiazepine receptor activity	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0019203	carbohydrate phosphatase activity	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0019206	nucleoside kinase activity	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0019864	IgG binding	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0034056	estrogen response element binding	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0035252	UDP-xylosyltransferase activity	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0042285	xylosyltransferase activity	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0047676	arachidonate-CoA ligase activity	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0048407	platelet-derived growth factor binding	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0140031	phosphorylation-dependent protein binding	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0140537	transcription regulator activator activity	2/2249	11/18639	0.181818181818182	1.50685152997292	0.390080488425687	0.758948140622787
GO:0016831	carboxy-lyase activity	5/2249	34/18639	0.147058823529412	1.21877697277221	0.392236276993072	0.761991440071005
GO:0042056	chemoattractant activity	6/2249	42/18639	0.142857142857143	1.18395477355015	0.396466937854439	0.769050325235719
GO:0005506	iron ion binding	20/2249	154/18639	0.12987012987013	1.07632252140923	0.398479959775817	0.770883795177212
GO:0005007	fibroblast growth factor receptor activity	7/2249	50/18639	0.14	1.16027567807915	0.399117619491951	0.770883795177212
GO:0015293	symporter activity	19/2249	146/18639	0.13013698630137	1.07853414302856	0.399207679645342	0.770883795177212
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	11/2249	82/18639	0.134146341463415	1.11176240930929	0.402606542035145	0.775122909030294
GO:0033549	MAP kinase phosphatase activity	11/2249	82/18639	0.134146341463415	1.11176240930929	0.402606542035145	0.775122909030294
GO:0042577	lipid phosphatase activity	3/2249	19/18639	0.157894736842105	1.30858159181859	0.406838804387344	0.780936482937257
GO:0120227	acyl-CoA binding	3/2249	19/18639	0.157894736842105	1.30858159181859	0.406838804387344	0.780936482937257
GO:0005385	zinc ion transmembrane transporter activity	4/2249	27/18639	0.148148148148148	1.2278049503483	0.413866499270057	0.789718594162717
GO:0008266	poly(U) RNA binding	4/2249	27/18639	0.148148148148148	1.2278049503483	0.413866499270057	0.789718594162717
GO:0008320	protein transmembrane transporter activity	4/2249	27/18639	0.148148148148148	1.2278049503483	0.413866499270057	0.789718594162717
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	4/2249	27/18639	0.148148148148148	1.2278049503483	0.413866499270057	0.789718594162717
GO:0005343	organic acid:sodium symporter activity	5/2249	35/18639	0.142857142857143	1.18395477355015	0.417310323947383	0.789970626468632
GO:0034061	DNA polymerase activity	5/2249	35/18639	0.142857142857143	1.18395477355015	0.417310323947383	0.789970626468632
GO:0016500	protein-hormone receptor activity	9/2249	67/18639	0.134328358208955	1.11327090647253	0.419796820975932	0.789970626468632
GO:0050840	extracellular matrix binding	9/2249	67/18639	0.134328358208955	1.11327090647253	0.419796820975932	0.789970626468632
GO:0005010	insulin-like growth factor receptor activity	7/2249	51/18639	0.137254901960784	1.1375251745874	0.419798875653248	0.789970626468632
GO:0005030	neurotrophin receptor activity	7/2249	51/18639	0.137254901960784	1.1375251745874	0.419798875653248	0.789970626468632
GO:0004879	nuclear receptor activity	8/2249	59/18639	0.135593220338983	1.12375368336963	0.41998516765026	0.789970626468632
GO:0046982	protein heterodimerization activity	46/2249	369/18639	0.124661246612466	1.03315294602479	0.429893260168142	0.789970626468632
GO:0052689	carboxylic ester hydrolase activity	12/2249	92/18639	0.130434782608696	1.08100218454579	0.43339525947222	0.789970626468632
GO:0000340	RNA 7-methylguanosine cap binding	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0004859	phospholipase inhibitor activity	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0005049	nuclear export signal receptor activity	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0005095	GTPase inhibitor activity	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0005165	neurotrophin receptor binding	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0008603	cAMP-dependent protein kinase regulator activity	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0016423	tRNA (guanine) methyltransferase activity	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0017166	vinculin binding	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0035497	cAMP response element binding	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0036009	protein-glutamine N-methyltransferase activity	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0045295	gamma-catenin binding	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0070008	serine-type exopeptidase activity	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0070410	co-SMAD binding	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0070679	inositol 1,4,5 trisphosphate binding	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	2/2249	12/18639	0.166666666666667	1.38128056914184	0.43436401517074	0.789970626468632
GO:0017018	myosin phosphatase activity	11/2249	84/18639	0.130952380952381	1.0852918757543	0.434869426646377	0.789970626468632
GO:0098531	ligand-modulated transcription factor activity	8/2249	60/18639	0.133333333333333	1.10502445531347	0.439141366887763	0.789970626468632
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	7/2249	52/18639	0.134615384615385	1.11564969046072	0.440410556395711	0.789970626468632
GO:0001614	purinergic nucleotide receptor activity	3/2249	20/18639	0.15	1.24315251222766	0.440614065804554	0.789970626468632
GO:0016502	nucleotide receptor activity	3/2249	20/18639	0.15	1.24315251222766	0.440614065804554	0.789970626468632
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/2249	20/18639	0.15	1.24315251222766	0.440614065804554	0.789970626468632
GO:0052745	inositol phosphate phosphatase activity	3/2249	20/18639	0.15	1.24315251222766	0.440614065804554	0.789970626468632
GO:0001223	transcription coactivator binding	6/2249	44/18639	0.136363636363636	1.13013864747969	0.441486930092692	0.789970626468632
GO:0016248	channel inhibitor activity	6/2249	44/18639	0.136363636363636	1.13013864747969	0.441486930092692	0.789970626468632
GO:0030020	extracellular matrix structural constituent conferring tensile strength	6/2249	44/18639	0.136363636363636	1.13013864747969	0.441486930092692	0.789970626468632
GO:0003823	antigen binding	22/2249	174/18639	0.126436781609195	1.04786801796967	0.441677993794309	0.789970626468632
GO:0004869	cysteine-type endopeptidase inhibitor activity	5/2249	36/18639	0.138888888888889	1.15106714095153	0.442205073057944	0.789970626468632
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	5/2249	36/18639	0.138888888888889	1.15106714095153	0.442205073057944	0.789970626468632
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	5/2249	36/18639	0.138888888888889	1.15106714095153	0.442205073057944	0.789970626468632
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	5/2249	36/18639	0.138888888888889	1.15106714095153	0.442205073057944	0.789970626468632
GO:0036408	histone H3K14 acetyltransferase activity	4/2249	28/18639	0.142857142857143	1.18395477355015	0.442211818077549	0.789970626468632
GO:0141052	histone H3 demethylase activity	4/2249	28/18639	0.142857142857143	1.18395477355015	0.442211818077549	0.789970626468632
GO:0016741	transferase activity, transferring one-carbon groups	27/2249	215/18639	0.125581395348837	1.04077884744641	0.443086880303674	0.790437537162233
GO:0019842	vitamin binding	19/2249	150/18639	0.126666666666667	1.0497732325478	0.447512749102779	0.797228797848381
GO:0051213	dioxygenase activity	12/2249	93/18639	0.129032258064516	1.06937850514207	0.448774931347522	0.798373082286752
GO:0019905	syntaxin binding	8/2249	61/18639	0.131147540983607	1.08690930030833	0.458211831907144	0.810260241572689
GO:0005003	ephrin receptor activity	7/2249	53/18639	0.132075471698113	1.09459969630108	0.460900206630738	0.810260241572689
GO:0005005	transmembrane-ephrin receptor activity	7/2249	53/18639	0.132075471698113	1.09459969630108	0.460900206630738	0.810260241572689
GO:0016251	RNA polymerase II general transcription initiation factor activity	7/2249	53/18639	0.132075471698113	1.09459969630108	0.460900206630738	0.810260241572689
GO:0038064	collagen receptor activity	7/2249	53/18639	0.132075471698113	1.09459969630108	0.460900206630738	0.810260241572689
GO:0015171	amino acid transmembrane transporter activity	13/2249	102/18639	0.127450980392157	1.05627337640258	0.461382016934068	0.810260241572689
GO:0141110	transporter inhibitor activity	6/2249	45/18639	0.133333333333333	1.10502445531347	0.463764522291319	0.810260241572689
GO:0016757	glycosyltransferase activity	33/2249	267/18639	0.123595505617978	1.02432042206024	0.469360235116854	0.810260241572689
GO:0019199	transmembrane receptor protein kinase activity	10/2249	78/18639	0.128205128205128	1.06252351472449	0.470128438561082	0.810260241572689
GO:0003785	actin monomer binding	4/2249	29/18639	0.137931034482759	1.14312874687601	0.470129040479131	0.810260241572689
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	4/2249	29/18639	0.137931034482759	1.14312874687601	0.470129040479131	0.810260241572689
GO:0010484	histone H3 acetyltransferase activity	4/2249	29/18639	0.137931034482759	1.14312874687601	0.470129040479131	0.810260241572689
GO:0035250	UDP-galactosyltransferase activity	4/2249	29/18639	0.137931034482759	1.14312874687601	0.470129040479131	0.810260241572689
GO:0097472	cyclin-dependent protein kinase activity	4/2249	29/18639	0.137931034482759	1.14312874687601	0.470129040479131	0.810260241572689
GO:0097110	scaffold protein binding	9/2249	70/18639	0.128571428571429	1.06555929619513	0.473487626199296	0.810260241572689
GO:0005123	death receptor binding	3/2249	21/18639	0.142857142857143	1.18395477355015	0.473615143269269	0.810260241572689
GO:0015174	basic amino acid transmembrane transporter activity	3/2249	21/18639	0.142857142857143	1.18395477355015	0.473615143269269	0.810260241572689
GO:0051010	microtubule plus-end binding	3/2249	21/18639	0.142857142857143	1.18395477355015	0.473615143269269	0.810260241572689
GO:0061891	calcium ion sensor activity	3/2249	21/18639	0.142857142857143	1.18395477355015	0.473615143269269	0.810260241572689
GO:0072542	protein phosphatase activator activity	3/2249	21/18639	0.142857142857143	1.18395477355015	0.473615143269269	0.810260241572689
GO:0140312	cargo adaptor activity	3/2249	21/18639	0.142857142857143	1.18395477355015	0.473615143269269	0.810260241572689
GO:1904047	S-adenosyl-L-methionine binding	3/2249	21/18639	0.142857142857143	1.18395477355015	0.473615143269269	0.810260241572689
GO:0004842	ubiquitin-protein transferase activity	55/2249	449/18639	0.122494432071269	1.01519507308866	0.47407351653686	0.810260241572689
GO:0004722	protein serine/threonine phosphatase activity	13/2249	103/18639	0.12621359223301	1.04601829507829	0.476047876649153	0.810260241572689
GO:0002161	aminoacyl-tRNA editing activity	2/2249	13/18639	0.153846153846154	1.27502821766939	0.47684570117399	0.810260241572689
GO:0003964	RNA-directed DNA polymerase activity	2/2249	13/18639	0.153846153846154	1.27502821766939	0.47684570117399	0.810260241572689
GO:0005338	nucleotide-sugar transmembrane transporter activity	2/2249	13/18639	0.153846153846154	1.27502821766939	0.47684570117399	0.810260241572689
GO:0017154	semaphorin receptor activity	2/2249	13/18639	0.153846153846154	1.27502821766939	0.47684570117399	0.810260241572689
GO:0035673	oligopeptide transmembrane transporter activity	2/2249	13/18639	0.153846153846154	1.27502821766939	0.47684570117399	0.810260241572689
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/2249	13/18639	0.153846153846154	1.27502821766939	0.47684570117399	0.810260241572689
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/2249	13/18639	0.153846153846154	1.27502821766939	0.47684570117399	0.810260241572689
GO:0070700	BMP receptor binding	2/2249	13/18639	0.153846153846154	1.27502821766939	0.47684570117399	0.810260241572689
GO:0071837	HMG box domain binding	2/2249	13/18639	0.153846153846154	1.27502821766939	0.47684570117399	0.810260241572689
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/2249	13/18639	0.153846153846154	1.27502821766939	0.47684570117399	0.810260241572689
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	6/2249	46/18639	0.130434782608696	1.08100218454579	0.485803541533801	0.823309159862547
GO:0030291	protein serine/threonine kinase inhibitor activity	6/2249	46/18639	0.130434782608696	1.08100218454579	0.485803541533801	0.823309159862547
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	5/2249	38/18639	0.131578947368421	1.09048465984882	0.491115794504489	0.83121832236765
GO:0001968	fibronectin binding	4/2249	30/18639	0.133333333333333	1.10502445531347	0.497511124126167	0.833199190124447
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	4/2249	30/18639	0.133333333333333	1.10502445531347	0.497511124126167	0.833199190124447
GO:0032452	histone demethylase activity	4/2249	30/18639	0.133333333333333	1.10502445531347	0.497511124126167	0.833199190124447
GO:0033612	receptor serine/threonine kinase binding	4/2249	30/18639	0.133333333333333	1.10502445531347	0.497511124126167	0.833199190124447
GO:0043995	histone H4K5 acetyltransferase activity	4/2249	30/18639	0.133333333333333	1.10502445531347	0.497511124126167	0.833199190124447
GO:0043996	histone H4K8 acetyltransferase activity	4/2249	30/18639	0.133333333333333	1.10502445531347	0.497511124126167	0.833199190124447
GO:0043997	histone H4K12 acetyltransferase activity	4/2249	30/18639	0.133333333333333	1.10502445531347	0.497511124126167	0.833199190124447
GO:0070566	adenylyltransferase activity	4/2249	30/18639	0.133333333333333	1.10502445531347	0.497511124126167	0.833199190124447
GO:0061630	ubiquitin protein ligase activity	43/2249	353/18639	0.121813031161473	1.00954783806967	0.498108211487441	0.833199190124447
GO:0003730	mRNA 3'-UTR binding	32/2249	262/18639	0.122137404580153	1.01223614227188	0.49921699441349	0.833970802599968
GO:0031683	G-protein beta/gamma-subunit complex binding	3/2249	22/18639	0.136363636363636	1.13013864747969	0.505689837383337	0.843420803501965
GO:0001784	phosphotyrosine residue binding	6/2249	47/18639	0.127659574468085	1.05800213806609	0.507547295572196	0.843420803501965
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	5/2249	39/18639	0.128205128205128	1.06252351472449	0.514980958940999	0.843420803501965
GO:0005161	platelet-derived growth factor receptor binding	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:0005545	1-phosphatidylinositol binding	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:0008474	palmitoyl-(protein) hydrolase activity	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:0008494	translation activator activity	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:0008559	ABC-type xenobiotic transporter activity	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:0015386	potassium:proton antiporter activity	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:0015926	glucosidase activity	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:0019763	immunoglobulin receptor activity	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:0032036	myosin heavy chain binding	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:0042813	Wnt receptor activity	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:0043176	amine binding	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:0046030	inositol trisphosphate phosphatase activity	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:0098599	palmitoyl hydrolase activity	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:1901474	azole transmembrane transporter activity	2/2249	14/18639	0.142857142857143	1.18395477355015	0.517315554942976	0.843420803501965
GO:0005164	tumor necrosis factor receptor binding	4/2249	31/18639	0.129032258064516	1.06937850514207	0.524265228579812	0.851517798752582
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/2249	31/18639	0.129032258064516	1.06937850514207	0.524265228579812	0.851517798752582
GO:0140457	protein demethylase activity	4/2249	31/18639	0.129032258064516	1.06937850514207	0.524265228579812	0.851517798752582
GO:0032266	phosphatidylinositol-3-phosphate binding	6/2249	48/18639	0.125	1.03596042685638	0.528944063555308	0.858035206371835
GO:0005283	amino acid:sodium symporter activity	3/2249	23/18639	0.130434782608696	1.08100218454579	0.536715475191552	0.864606617746624
GO:0016493	C-C chemokine receptor activity	3/2249	23/18639	0.130434782608696	1.08100218454579	0.536715475191552	0.864606617746624
GO:0017134	fibroblast growth factor binding	3/2249	23/18639	0.130434782608696	1.08100218454579	0.536715475191552	0.864606617746624
GO:0043274	phospholipase binding	3/2249	23/18639	0.130434782608696	1.08100218454579	0.536715475191552	0.864606617746624
GO:0140103	catalytic activity, acting on a glycoprotein	3/2249	23/18639	0.130434782608696	1.08100218454579	0.536715475191552	0.864606617746624
GO:0004674	protein serine/threonine kinase activity	52/2249	433/18639	0.120092378752887	0.99528761564031	0.537251571425041	0.864606617746624
GO:0004532	RNA exonuclease activity	5/2249	40/18639	0.125	1.03596042685638	0.538365300801858	0.864606617746624
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	5/2249	40/18639	0.125	1.03596042685638	0.538365300801858	0.864606617746624
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/2249	32/18639	0.125	1.03596042685638	0.550312204815887	0.875966819574718
GO:0042910	xenobiotic transmembrane transporter activity	4/2249	32/18639	0.125	1.03596042685638	0.550312204815887	0.875966819574718
GO:0140142	nucleocytoplasmic carrier activity	4/2249	32/18639	0.125	1.03596042685638	0.550312204815887	0.875966819574718
GO:0008235	metalloexopeptidase activity	8/2249	66/18639	0.121212121212121	1.00456768664861	0.550930819377728	0.875966819574718
GO:0043130	ubiquitin binding	12/2249	100/18639	0.12	0.994522009782125	0.554124970731302	0.875966819574718
GO:0004467	long-chain fatty acid-CoA ligase activity	2/2249	15/18639	0.133333333333333	1.10502445531347	0.555640443783031	0.875966819574718
GO:0004953	icosanoid receptor activity	2/2249	15/18639	0.133333333333333	1.10502445531347	0.555640443783031	0.875966819574718
GO:0005402	carbohydrate:monoatomic cation symporter activity	2/2249	15/18639	0.133333333333333	1.10502445531347	0.555640443783031	0.875966819574718
GO:0005523	tropomyosin binding	2/2249	15/18639	0.133333333333333	1.10502445531347	0.555640443783031	0.875966819574718
GO:0008020	G protein-coupled photoreceptor activity	2/2249	15/18639	0.133333333333333	1.10502445531347	0.555640443783031	0.875966819574718
GO:0015116	sulfate transmembrane transporter activity	2/2249	15/18639	0.133333333333333	1.10502445531347	0.555640443783031	0.875966819574718
GO:0048531	beta-1,3-galactosyltransferase activity	2/2249	15/18639	0.133333333333333	1.10502445531347	0.555640443783031	0.875966819574718
GO:0050700	CARD domain binding	2/2249	15/18639	0.133333333333333	1.10502445531347	0.555640443783031	0.875966819574718
GO:0141050	histone H3K deacetylase activity	2/2249	15/18639	0.133333333333333	1.10502445531347	0.555640443783031	0.875966819574718
GO:0141051	histone H4K deacetylase activity	2/2249	15/18639	0.133333333333333	1.10502445531347	0.555640443783031	0.875966819574718
GO:0004812	aminoacyl-tRNA ligase activity	5/2249	41/18639	0.121951219512195	1.01069309937208	0.561213059112301	0.881515146508102
GO:0016875	ligase activity, forming carbon-oxygen bonds	5/2249	41/18639	0.121951219512195	1.01069309937208	0.561213059112301	0.881515146508102
GO:0140318	protein transporter activity	5/2249	41/18639	0.121951219512195	1.01069309937208	0.561213059112301	0.881515146508102
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	3/2249	24/18639	0.125	1.03596042685638	0.566596230330938	0.888886656109925
GO:0140098	catalytic activity, acting on RNA	46/2249	387/18639	0.118863049095607	0.985099320628289	0.567489085340993	0.889204308904135
GO:0030414	peptidase inhibitor activity	20/2249	169/18639	0.118343195266272	0.980790936668763	0.572574883925021	0.8960831719264
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	4/2249	33/18639	0.121212121212121	1.00456768664861	0.575585933845542	0.898611736718858
GO:0030296	protein tyrosine kinase activator activity	4/2249	33/18639	0.121212121212121	1.00456768664861	0.575585933845542	0.898611736718858
GO:0004866	endopeptidase inhibitor activity	19/2249	161/18639	0.118012422360248	0.978049595541428	0.577670804729962	0.900774814155195
GO:0045309	protein phosphorylated amino acid binding	7/2249	59/18639	0.11864406779661	0.983284472948429	0.578737255889693	0.901346536379594
GO:0016859	cis-trans isomerase activity	5/2249	42/18639	0.119047619047619	0.986628977958458	0.583476048471472	0.9076294087334
GO:0032934	sterol binding	8/2249	68/18639	0.117647058823529	0.97502157821777	0.586171165645712	0.909624652230936
GO:0140223	general transcription initiation factor activity	8/2249	68/18639	0.117647058823529	0.97502157821777	0.586171165645712	0.909624652230936
GO:0008296	3'-5'-DNA exonuclease activity	2/2249	16/18639	0.125	1.03596042685638	0.591748616678235	0.911647305953571
GO:0015385	sodium:proton antiporter activity	2/2249	16/18639	0.125	1.03596042685638	0.591748616678235	0.911647305953571
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/2249	16/18639	0.125	1.03596042685638	0.591748616678235	0.911647305953571
GO:0022841	potassium ion leak channel activity	2/2249	16/18639	0.125	1.03596042685638	0.591748616678235	0.911647305953571
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	2/2249	16/18639	0.125	1.03596042685638	0.591748616678235	0.911647305953571
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/2249	16/18639	0.125	1.03596042685638	0.591748616678235	0.911647305953571
GO:0008139	nuclear localization sequence binding	3/2249	25/18639	0.12	0.994522009782125	0.595260391542666	0.911647305953571
GO:0015645	fatty acid ligase activity	3/2249	25/18639	0.12	0.994522009782125	0.595260391542666	0.911647305953571
GO:0017025	TBP-class protein binding	3/2249	25/18639	0.12	0.994522009782125	0.595260391542666	0.911647305953571
GO:0019211	phosphatase activator activity	3/2249	25/18639	0.12	0.994522009782125	0.595260391542666	0.911647305953571
GO:0120515	fatty acid-CoA ligase activity	3/2249	25/18639	0.12	0.994522009782125	0.595260391542666	0.911647305953571
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	7/2249	60/18639	0.116666666666667	0.966896398399289	0.597174448776741	0.91349250596727
GO:0019825	oxygen binding	4/2249	34/18639	0.117647058823529	0.97502157821777	0.600032554759205	0.916775718303506
GO:0008200	ion channel inhibitor activity	5/2249	43/18639	0.116279069767442	0.963684118005935	0.605113380935397	0.921506750923006
GO:0008375	acetylglucosaminyltransferase activity	5/2249	43/18639	0.116279069767442	0.963684118005935	0.605113380935397	0.921506750923006
GO:0004867	serine-type endopeptidase inhibitor activity	11/2249	95/18639	0.115789473684211	0.959626500666963	0.605275396957192	0.921506750923006
GO:0030159	signaling receptor complex adaptor activity	6/2249	52/18639	0.115384615384615	0.956271163252044	0.610201518909511	0.927909747763223
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	15/2249	130/18639	0.115384615384615	0.956271163252044	0.613871169525265	0.932389229184601
GO:0015103	inorganic anion transmembrane transporter activity	19/2249	165/18639	0.115151515151515	0.954339302316181	0.622198915567904	0.934421062322069
GO:0043548	phosphatidylinositol 3-kinase binding	3/2249	26/18639	0.115384615384615	0.956271163252044	0.622657663273244	0.934421062322069
GO:0000175	3'-5'-RNA exonuclease activity	4/2249	35/18639	0.114285714285714	0.947163818840119	0.62360961679944	0.934421062322069
GO:0010485	histone H4 acetyltransferase activity	4/2249	35/18639	0.114285714285714	0.947163818840119	0.62360961679944	0.934421062322069
GO:0016229	steroid dehydrogenase activity	4/2249	35/18639	0.114285714285714	0.947163818840119	0.62360961679944	0.934421062322069
GO:0140566	histone reader activity	4/2249	35/18639	0.114285714285714	0.947163818840119	0.62360961679944	0.934421062322069
GO:0016835	carbon-oxygen lyase activity	9/2249	79/18639	0.113924050632911	0.94416646498303	0.624726537098954	0.934421062322069
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/2249	17/18639	0.117647058823529	0.97502157821777	0.625616840664023	0.934421062322069
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	2/2249	17/18639	0.117647058823529	0.97502157821777	0.625616840664023	0.934421062322069
GO:0008429	phosphatidylethanolamine binding	2/2249	17/18639	0.117647058823529	0.97502157821777	0.625616840664023	0.934421062322069
GO:0009881	photoreceptor activity	2/2249	17/18639	0.117647058823529	0.97502157821777	0.625616840664023	0.934421062322069
GO:0031489	myosin V binding	2/2249	17/18639	0.117647058823529	0.97502157821777	0.625616840664023	0.934421062322069
GO:0045125	bioactive lipid receptor activity	2/2249	17/18639	0.117647058823529	0.97502157821777	0.625616840664023	0.934421062322069
GO:0048038	quinone binding	2/2249	17/18639	0.117647058823529	0.97502157821777	0.625616840664023	0.934421062322069
GO:0043014	alpha-tubulin binding	5/2249	44/18639	0.113636363636364	0.941782206233073	0.626091131043436	0.934421062322069
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	19/2249	167/18639	0.11377245508982	0.942910089114789	0.643634567020687	0.959355278645755
GO:0044390	ubiquitin-like protein conjugating enzyme binding	4/2249	36/18639	0.111111111111111	0.920853712761227	0.646285184767127	0.959355278645755
GO:0008009	chemokine activity	5/2249	45/18639	0.111111111111111	0.920853712761227	0.64638195713745	0.959355278645755
GO:0015485	cholesterol binding	6/2249	54/18639	0.111111111111111	0.920853712761227	0.64776661916928	0.959355278645755
GO:0004683	calcium/calmodulin-dependent protein kinase activity	3/2249	27/18639	0.111111111111111	0.920853712761227	0.648756558773643	0.959355278645755
GO:0008395	steroid hydroxylase activity	3/2249	27/18639	0.111111111111111	0.920853712761227	0.648756558773643	0.959355278645755
GO:0016405	CoA-ligase activity	3/2249	27/18639	0.111111111111111	0.920853712761227	0.648756558773643	0.959355278645755
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	3/2249	27/18639	0.111111111111111	0.920853712761227	0.648756558773643	0.959355278645755
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/2249	18/18639	0.111111111111111	0.920853712761227	0.657259745736126	0.96527999145739
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/2249	18/18639	0.111111111111111	0.920853712761227	0.657259745736126	0.96527999145739
GO:0017075	syntaxin-1 binding	2/2249	18/18639	0.111111111111111	0.920853712761227	0.657259745736126	0.96527999145739
GO:0022851	GABA-gated chloride ion channel activity	2/2249	18/18639	0.111111111111111	0.920853712761227	0.657259745736126	0.96527999145739
GO:0032393	MHC class I receptor activity	2/2249	18/18639	0.111111111111111	0.920853712761227	0.657259745736126	0.96527999145739
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	2/2249	18/18639	0.111111111111111	0.920853712761227	0.657259745736126	0.96527999145739
GO:0098632	cell-cell adhesion mediator activity	6/2249	55/18639	0.109090909090909	0.90411091798375	0.665698994410371	0.974730138276108
GO:0004180	carboxypeptidase activity	5/2249	46/18639	0.108695652173913	0.900835153788157	0.665964690747651	0.974730138276108
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	5/2249	46/18639	0.108695652173913	0.900835153788157	0.665964690747651	0.974730138276108
GO:0019213	deacetylase activity	4/2249	37/18639	0.108108108108108	0.895965774578491	0.668036922218003	0.975545981651686
GO:0043394	proteoglycan binding	4/2249	37/18639	0.108108108108108	0.895965774578491	0.668036922218003	0.975545981651686
GO:0015297	antiporter activity	15/2249	135/18639	0.111111111111111	0.920853712761227	0.672954642552031	0.976556991126034
GO:0046625	sphingolipid binding	3/2249	28/18639	0.107142857142857	0.887966080162612	0.673541927657174	0.976556991126034
GO:0046875	ephrin receptor binding	3/2249	28/18639	0.107142857142857	0.887966080162612	0.673541927657174	0.976556991126034
GO:0051019	mitogen-activated protein kinase binding	3/2249	28/18639	0.107142857142857	0.887966080162612	0.673541927657174	0.976556991126034
GO:0051959	dynein light intermediate chain binding	3/2249	28/18639	0.107142857142857	0.887966080162612	0.673541927657174	0.976556991126034
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	3/2249	28/18639	0.107142857142857	0.887966080162612	0.673541927657174	0.976556991126034
GO:0003774	cytoskeletal motor activity	17/2249	153/18639	0.111111111111111	0.920853712761227	0.678853230933954	0.976556991126034
GO:0030170	pyridoxal phosphate binding	6/2249	56/18639	0.107142857142857	0.887966080162612	0.683043819969785	0.976556991126034
GO:0016779	nucleotidyltransferase activity	15/2249	136/18639	0.110294117647059	0.914082729579159	0.68414679261123	0.976556991126034
GO:0140938	histone H3 methyltransferase activity	5/2249	47/18639	0.106382978723404	0.881668448388409	0.684823904459015	0.976556991126034
GO:0005126	cytokine receptor binding	31/2249	275/18639	0.112727272727273	0.934247948583209	0.685341121772975	0.976556991126034
GO:0043178	alcohol binding	10/2249	92/18639	0.108695652173913	0.900835153788157	0.685392479357323	0.976556991126034
GO:0106310	protein serine kinase activity	41/2249	361/18639	0.113573407202216	0.94126044323793	0.685783809933508	0.976556991126034
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/2249	19/18639	0.105263157894737	0.872387727879057	0.68672103295363	0.976556991126034
GO:0004890	GABA-A receptor activity	2/2249	19/18639	0.105263157894737	0.872387727879057	0.68672103295363	0.976556991126034
GO:0016918	retinal binding	2/2249	19/18639	0.105263157894737	0.872387727879057	0.68672103295363	0.976556991126034
GO:0022821	solute:potassium antiporter activity	2/2249	19/18639	0.105263157894737	0.872387727879057	0.68672103295363	0.976556991126034
GO:0022840	leak channel activity	2/2249	19/18639	0.105263157894737	0.872387727879057	0.68672103295363	0.976556991126034
GO:0022842	narrow pore channel activity	2/2249	19/18639	0.105263157894737	0.872387727879057	0.68672103295363	0.976556991126034
GO:0031420	alkali metal ion binding	2/2249	19/18639	0.105263157894737	0.872387727879057	0.68672103295363	0.976556991126034
GO:0097001	ceramide binding	2/2249	19/18639	0.105263157894737	0.872387727879057	0.68672103295363	0.976556991126034
GO:0140036	ubiquitin-modified protein reader activity	2/2249	19/18639	0.105263157894737	0.872387727879057	0.68672103295363	0.976556991126034
GO:0005516	calmodulin binding	23/2249	207/18639	0.111111111111111	0.920853712761227	0.695670951860363	0.976556991126034
GO:0005416	amino acid:monoatomic cation symporter activity	3/2249	29/18639	0.103448275862069	0.857346560157005	0.697012645408487	0.976556991126034
GO:0043236	laminin binding	3/2249	29/18639	0.103448275862069	0.857346560157005	0.697012645408487	0.976556991126034
GO:0051861	glycolipid binding	3/2249	29/18639	0.103448275862069	0.857346560157005	0.697012645408487	0.976556991126034
GO:0051117	ATPase binding	9/2249	84/18639	0.107142857142857	0.887966080162612	0.697898936208049	0.976556991126034
GO:0070279	vitamin B6 binding	6/2249	57/18639	0.105263157894737	0.872387727879057	0.699790318382192	0.976556991126034
GO:1902936	phosphatidylinositol bisphosphate binding	12/2249	111/18639	0.108108108108108	0.895965774578491	0.700941616692826	0.976556991126034
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/2249	39/18639	0.102564102564103	0.850018811779594	0.708722054091096	0.976556991126034
GO:0008173	RNA methyltransferase activity	7/2249	67/18639	0.104477611940299	0.865877371700855	0.713340240379248	0.976556991126034
GO:0042054	histone methyltransferase activity	7/2249	67/18639	0.104477611940299	0.865877371700855	0.713340240379248	0.976556991126034
GO:0015464	acetylcholine receptor activity	2/2249	20/18639	0.1	0.828768341485104	0.714066251525749	0.976556991126034
GO:0031418	L-ascorbic acid binding	2/2249	20/18639	0.1	0.828768341485104	0.714066251525749	0.976556991126034
GO:0061608	nuclear import signal receptor activity	2/2249	20/18639	0.1	0.828768341485104	0.714066251525749	0.976556991126034
GO:0140664	ATP-dependent DNA damage sensor activity	2/2249	20/18639	0.1	0.828768341485104	0.714066251525749	0.976556991126034
GO:0070851	growth factor receptor binding	15/2249	139/18639	0.107913669064748	0.894354325343638	0.716372966635081	0.976556991126034
GO:0140101	catalytic activity, acting on a tRNA	15/2249	139/18639	0.107913669064748	0.894354325343638	0.716372966635081	0.976556991126034
GO:0001965	G-protein alpha-subunit binding	3/2249	30/18639	0.1	0.828768341485104	0.719179481106522	0.976556991126034
GO:0035254	glutamate receptor binding	5/2249	49/18639	0.102040816326531	0.845681981107249	0.72033609587929	0.976556991126034
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0004983	neuropeptide Y receptor activity	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0005031	tumor necrosis factor receptor activity	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0005131	growth hormone receptor binding	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0005381	iron ion transmembrane transporter activity	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0015187	glycine transmembrane transporter activity	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0015203	polyamine transmembrane transporter activity	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0031419	cobalamin binding	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0032052	bile acid binding	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0042166	acetylcholine binding	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0043295	glutathione binding	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0045322	unmethylated CpG binding	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0050815	phosphoserine residue binding	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0051378	serotonin binding	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0070097	delta-catenin binding	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0140135	mechanosensitive monoatomic cation channel activity	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:1905394	retromer complex binding	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:1990763	arrestin family protein binding	1/2249	10/18639	0.1	0.828768341485104	0.72367541571736	0.976556991126034
GO:0008276	protein methyltransferase activity	10/2249	95/18639	0.105263157894737	0.872387727879057	0.723918441235519	0.976556991126034
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	9/2249	86/18639	0.104651162790698	0.867315706205342	0.724490210014973	0.976556991126034
GO:0004713	protein tyrosine kinase activity	15/2249	140/18639	0.107142857142857	0.887966080162612	0.726651372122025	0.976556991126034
GO:0032451	demethylase activity	4/2249	40/18639	0.1	0.828768341485104	0.727650582234344	0.976556991126034
GO:0071949	FAD binding	4/2249	40/18639	0.1	0.828768341485104	0.727650582234344	0.976556991126034
GO:0001786	phosphatidylserine binding	6/2249	59/18639	0.101694915254237	0.842815262527225	0.73146264324651	0.976556991126034
GO:0015459	potassium channel regulator activity	6/2249	59/18639	0.101694915254237	0.842815262527225	0.73146264324651	0.976556991126034
GO:1901981	phosphatidylinositol phosphate binding	20/2249	185/18639	0.108108108108108	0.895965774578491	0.73344158876057	0.976556991126034
GO:0008373	sialyltransferase activity	2/2249	21/18639	0.0952380952380952	0.789303182366766	0.739376894500116	0.976556991126034
GO:0035613	RNA stem-loop binding	2/2249	21/18639	0.0952380952380952	0.789303182366766	0.739376894500116	0.976556991126034
GO:0036122	BMP binding	2/2249	21/18639	0.0952380952380952	0.789303182366766	0.739376894500116	0.976556991126034
GO:0005452	solute:inorganic anion antiporter activity	3/2249	31/18639	0.0967741935483871	0.802033878856553	0.740063151020098	0.976556991126034
GO:0016878	acid-thiol ligase activity	3/2249	31/18639	0.0967741935483871	0.802033878856553	0.740063151020098	0.976556991126034
GO:0017080	sodium channel regulator activity	4/2249	41/18639	0.0975609756097561	0.808554479497663	0.745643827977268	0.976556991126034
GO:0035401	histone H3Y41 kinase activity	12/2249	115/18639	0.104347826086957	0.864801747636631	0.746209801551314	0.976556991126034
GO:0140801	histone H2AXY142 kinase activity	12/2249	115/18639	0.104347826086957	0.864801747636631	0.746209801551314	0.976556991126034
GO:0033293	monocarboxylic acid binding	8/2249	79/18639	0.10126582278481	0.839259079984916	0.751966759060024	0.976556991126034
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0004016	adenylate cyclase activity	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0005536	D-glucose binding	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0008172	S-methyltransferase activity	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0008271	secondary active sulfate transmembrane transporter activity	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0008432	JUN kinase binding	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0016594	glycine binding	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0019107	myristoyltransferase activity	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0019215	intermediate filament binding	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0032050	clathrin heavy chain binding	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0032404	mismatch repair complex binding	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0032794	GTPase activating protein binding	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0034511	U3 snoRNA binding	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0045294	alpha-catenin binding	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0048185	activin binding	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0050998	nitric-oxide synthase binding	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0070697	activin receptor binding	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0180030	inositol phosphate kinase activity	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:1900750	oligopeptide binding	1/2249	11/18639	0.0909090909090909	0.753425764986459	0.757034908446528	0.976556991126034
GO:0043425	bHLH transcription factor binding	3/2249	32/18639	0.09375	0.776970320142286	0.75969255924812	0.976556991126034
GO:0004407	histone deacetylase activity	2/2249	22/18639	0.0909090909090909	0.753425764986459	0.762745600211794	0.976556991126034
GO:0005243	gap junction channel activity	2/2249	22/18639	0.0909090909090909	0.753425764986459	0.762745600211794	0.976556991126034
GO:0008093	cytoskeletal anchor activity	2/2249	22/18639	0.0909090909090909	0.753425764986459	0.762745600211794	0.976556991126034
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	2/2249	22/18639	0.0909090909090909	0.753425764986459	0.762745600211794	0.976556991126034
GO:0016881	acid-amino acid ligase activity	2/2249	22/18639	0.0909090909090909	0.753425764986459	0.762745600211794	0.976556991126034
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/2249	22/18639	0.0909090909090909	0.753425764986459	0.762745600211794	0.976556991126034
GO:0033558	protein lysine deacetylase activity	2/2249	22/18639	0.0909090909090909	0.753425764986459	0.762745600211794	0.976556991126034
GO:0140035	ubiquitin-like protein reader activity	2/2249	22/18639	0.0909090909090909	0.753425764986459	0.762745600211794	0.976556991126034
GO:0005496	steroid binding	11/2249	108/18639	0.101851851851852	0.844115903364458	0.768377002042345	0.982790048292493
GO:0008194	UDP-glycosyltransferase activity	15/2249	145/18639	0.103448275862069	0.857346560157005	0.774448014359513	0.984298144130189
GO:0030971	receptor tyrosine kinase binding	8/2249	81/18639	0.0987654320987654	0.818536633565535	0.776375310667802	0.984298144130189
GO:0001664	G protein-coupled receptor binding	32/2249	297/18639	0.107744107744108	0.892949054798766	0.779370699586614	0.984298144130189
GO:0005544	calcium-dependent phospholipid binding	5/2249	53/18639	0.0943396226415094	0.781856925929344	0.782532468008393	0.984298144130189
GO:0016917	GABA receptor activity	2/2249	23/18639	0.0869565217391304	0.720668123030526	0.78427227878515	0.984298144130189
GO:0003720	telomerase activity	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:0004032	aldose reductase (NADPH) activity	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:0005078	MAP-kinase scaffold activity	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:0005247	voltage-gated chloride channel activity	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:0005436	sodium:phosphate symporter activity	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:0016273	arginine N-methyltransferase activity	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:0016274	protein-arginine N-methyltransferase activity	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:0016840	carbon-nitrogen lyase activity	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:0034452	dynactin binding	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:0035197	siRNA binding	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:0035251	UDP-glucosyltransferase activity	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:1990459	transferrin receptor binding	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:1990817	poly(A) RNA polymerase activity	1/2249	12/18639	0.0833333333333333	0.69064028457092	0.786368626017053	0.984298144130189
GO:0004175	endopeptidase activity	44/2249	405/18639	0.108641975308642	0.900390296922089	0.794495858185783	0.991667566966464
GO:0008376	acetylgalactosaminyltransferase activity	3/2249	34/18639	0.0882352941176471	0.731266183663328	0.795335866984749	0.991667566966464
GO:0051427	hormone receptor binding	3/2249	34/18639	0.0882352941176471	0.731266183663328	0.795335866984749	0.991667566966464
GO:0052866	phosphatidylinositol phosphate phosphatase activity	3/2249	34/18639	0.0882352941176471	0.731266183663328	0.795335866984749	0.991667566966464
GO:0030165	PDZ domain binding	8/2249	83/18639	0.0963855421686747	0.798812859262751	0.798984408111515	0.993405624712955
GO:0140612	DNA damage sensor activity	2/2249	24/18639	0.0833333333333333	0.69064028457092	0.804061010462805	0.993405624712955
GO:0035064	methylated histone binding	7/2249	74/18639	0.0945945945945946	0.78397005275618	0.804618431641019	0.993405624712955
GO:0051219	phosphoprotein binding	9/2249	93/18639	0.0967741935483871	0.802033878856553	0.804924738912285	0.993405624712955
GO:0008509	monoatomic anion transmembrane transporter activity	15/2249	149/18639	0.100671140939597	0.834330545119233	0.8083161594448	0.993405624712955
GO:0043015	gamma-tubulin binding	3/2249	35/18639	0.0857142857142857	0.710372864130089	0.811435202939622	0.993405624712955
GO:0008168	methyltransferase activity	21/2249	204/18639	0.102941176470588	0.853143880940549	0.811703433998783	0.993405624712955
GO:0004465	lipoprotein lipase activity	1/2249	13/18639	0.0769230769230769	0.637514108834696	0.812162203087309	0.993405624712955
GO:0004535	poly(A)-specific ribonuclease activity	1/2249	13/18639	0.0769230769230769	0.637514108834696	0.812162203087309	0.993405624712955
GO:0005035	death receptor activity	1/2249	13/18639	0.0769230769230769	0.637514108834696	0.812162203087309	0.993405624712955
GO:0008253	5'-nucleotidase activity	1/2249	13/18639	0.0769230769230769	0.637514108834696	0.812162203087309	0.993405624712955
GO:0008417	fucosyltransferase activity	1/2249	13/18639	0.0769230769230769	0.637514108834696	0.812162203087309	0.993405624712955
GO:0019855	calcium channel inhibitor activity	1/2249	13/18639	0.0769230769230769	0.637514108834696	0.812162203087309	0.993405624712955
GO:0031432	titin binding	1/2249	13/18639	0.0769230769230769	0.637514108834696	0.812162203087309	0.993405624712955
GO:0031994	insulin-like growth factor I binding	1/2249	13/18639	0.0769230769230769	0.637514108834696	0.812162203087309	0.993405624712955
GO:0032396	inhibitory MHC class I receptor activity	1/2249	13/18639	0.0769230769230769	0.637514108834696	0.812162203087309	0.993405624712955
GO:0045159	myosin II binding	1/2249	13/18639	0.0769230769230769	0.637514108834696	0.812162203087309	0.993405624712955
GO:0140333	glycerophospholipid flippase activity	1/2249	13/18639	0.0769230769230769	0.637514108834696	0.812162203087309	0.993405624712955
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/2249	13/18639	0.0769230769230769	0.637514108834696	0.812162203087309	0.993405624712955
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/2249	13/18639	0.0769230769230769	0.637514108834696	0.812162203087309	0.993405624712955
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	12/2249	122/18639	0.0983606557377049	0.81518197523125	0.813839189251742	0.993405624712955
GO:0042562	hormone binding	9/2249	94/18639	0.0957446808510638	0.793501603549568	0.814824213648964	0.993405624712955
GO:0005179	hormone activity	13/2249	132/18639	0.0984848484848485	0.816211245401997	0.819834883130031	0.993405624712955
GO:0015271	outward rectifier potassium channel activity	2/2249	25/18639	0.08	0.663014673188084	0.822217586021078	0.993405624712955
GO:0015662	P-type ion transporter activity	2/2249	25/18639	0.08	0.663014673188084	0.822217586021078	0.993405624712955
GO:0140358	P-type transmembrane transporter activity	2/2249	25/18639	0.08	0.663014673188084	0.822217586021078	0.993405624712955
GO:0016758	hexosyltransferase activity	20/2249	197/18639	0.101522842639594	0.841389179172695	0.825488841826782	0.993405624712955
GO:0017022	myosin binding	7/2249	76/18639	0.0921052631578947	0.763339261894175	0.826141249690901	0.993405624712955
GO:0140034	methylation-dependent protein binding	7/2249	76/18639	0.0921052631578947	0.763339261894175	0.826141249690901	0.993405624712955
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	3/2249	36/18639	0.0833333333333333	0.69064028457092	0.826448840955304	0.993405624712955
GO:0005484	SNAP receptor activity	3/2249	36/18639	0.0833333333333333	0.69064028457092	0.826448840955304	0.993405624712955
GO:0051020	GTPase binding	33/2249	315/18639	0.104761904761905	0.868233500603443	0.831429038343835	0.993405624712955
GO:0004065	arylsulfatase activity	1/2249	14/18639	0.0714285714285714	0.591977386775075	0.834842714483027	0.993405624712955
GO:0004705	JUN kinase activity	1/2249	14/18639	0.0714285714285714	0.591977386775075	0.834842714483027	0.993405624712955
GO:0005313	L-glutamate transmembrane transporter activity	1/2249	14/18639	0.0714285714285714	0.591977386775075	0.834842714483027	0.993405624712955
GO:0008174	mRNA methyltransferase activity	1/2249	14/18639	0.0714285714285714	0.591977386775075	0.834842714483027	0.993405624712955
GO:0008191	metalloendopeptidase inhibitor activity	1/2249	14/18639	0.0714285714285714	0.591977386775075	0.834842714483027	0.993405624712955
GO:0008392	arachidonate epoxygenase activity	1/2249	14/18639	0.0714285714285714	0.591977386775075	0.834842714483027	0.993405624712955
GO:0019992	diacylglycerol binding	1/2249	14/18639	0.0714285714285714	0.591977386775075	0.834842714483027	0.993405624712955
GO:0030983	mismatched DNA binding	1/2249	14/18639	0.0714285714285714	0.591977386775075	0.834842714483027	0.993405624712955
GO:0032454	histone H3K9 demethylase activity	1/2249	14/18639	0.0714285714285714	0.591977386775075	0.834842714483027	0.993405624712955
GO:0042043	neurexin family protein binding	1/2249	14/18639	0.0714285714285714	0.591977386775075	0.834842714483027	0.993405624712955
GO:0071933	Arp2/3 complex binding	1/2249	14/18639	0.0714285714285714	0.591977386775075	0.834842714483027	0.993405624712955
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/2249	14/18639	0.0714285714285714	0.591977386775075	0.834842714483027	0.993405624712955
GO:0043495	protein-membrane adaptor activity	4/2249	47/18639	0.0851063829787234	0.705334758710727	0.834931015977206	0.993405624712955
GO:0008083	growth factor activity	16/2249	162/18639	0.0987654320987654	0.818536633565535	0.836563115490985	0.993405624712955
GO:0000149	SNARE binding	10/2249	106/18639	0.0943396226415094	0.781856925929344	0.8375512386592	0.993405624712955
GO:0019865	immunoglobulin binding	2/2249	26/18639	0.0769230769230769	0.637514108834696	0.838847579583398	0.993405624712955
GO:0030507	spectrin binding	2/2249	26/18639	0.0769230769230769	0.637514108834696	0.838847579583398	0.993405624712955
GO:0051139	metal cation:proton antiporter activity	2/2249	26/18639	0.0769230769230769	0.637514108834696	0.838847579583398	0.993405624712955
GO:0052742	phosphatidylinositol kinase activity	2/2249	26/18639	0.0769230769230769	0.637514108834696	0.838847579583398	0.993405624712955
GO:0097602	cullin family protein binding	2/2249	26/18639	0.0769230769230769	0.637514108834696	0.838847579583398	0.993405624712955
GO:0042805	actinin binding	3/2249	37/18639	0.0810810810810811	0.671974330933869	0.84042636319683	0.993405624712955
GO:0004677	DNA-dependent protein kinase activity	25/2249	246/18639	0.101626016260163	0.842244249476732	0.846892879220032	0.993405624712955
GO:0015081	sodium ion transmembrane transporter activity	16/2249	164/18639	0.0975609756097561	0.808554479497663	0.849934739090208	0.993405624712955
GO:0035402	histone H3T11 kinase activity	25/2249	247/18639	0.101214574898785	0.838834353729863	0.85223832250093	0.993405624712955
GO:0000146	microfilament motor activity	3/2249	38/18639	0.0789473684210526	0.654290795909293	0.853418522396223	0.993405624712955
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	2/2249	27/18639	0.0740740740740741	0.613902475174151	0.854054861248178	0.993405624712955
GO:0004089	carbonate dehydratase activity	1/2249	15/18639	0.0666666666666667	0.552512227656736	0.854785733818741	0.993405624712955
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	1/2249	15/18639	0.0666666666666667	0.552512227656736	0.854785733818741	0.993405624712955
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	1/2249	15/18639	0.0666666666666667	0.552512227656736	0.854785733818741	0.993405624712955
GO:0008242	omega peptidase activity	1/2249	15/18639	0.0666666666666667	0.552512227656736	0.854785733818741	0.993405624712955
GO:0008252	nucleotidase activity	1/2249	15/18639	0.0666666666666667	0.552512227656736	0.854785733818741	0.993405624712955
GO:0010181	FMN binding	1/2249	15/18639	0.0666666666666667	0.552512227656736	0.854785733818741	0.993405624712955
GO:0031005	filamin binding	1/2249	15/18639	0.0666666666666667	0.552512227656736	0.854785733818741	0.993405624712955
GO:0033130	acetylcholine receptor binding	1/2249	15/18639	0.0666666666666667	0.552512227656736	0.854785733818741	0.993405624712955
GO:0061578	K63-linked deubiquitinase activity	1/2249	15/18639	0.0666666666666667	0.552512227656736	0.854785733818741	0.993405624712955
GO:0120283	protein serine/threonine kinase binding	1/2249	15/18639	0.0666666666666667	0.552512227656736	0.854785733818741	0.993405624712955
GO:0070888	E-box binding	5/2249	59/18639	0.0847457627118644	0.702346052106021	0.855005654399625	0.993405624712955
GO:0048020	CCR chemokine receptor binding	4/2249	50/18639	0.08	0.663014673188084	0.868721129044435	0.993405624712955
GO:0140767	enzyme-substrate adaptor activity	13/2249	139/18639	0.0935251798561151	0.775107081964486	0.870215265175881	0.993405624712955
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	1/2249	16/18639	0.0625	0.51798021342819	0.872321541628108	0.993405624712955
GO:0004707	MAP kinase activity	1/2249	16/18639	0.0625	0.51798021342819	0.872321541628108	0.993405624712955
GO:0004708	MAP kinase kinase activity	1/2249	16/18639	0.0625	0.51798021342819	0.872321541628108	0.993405624712955
GO:0008391	arachidonate monooxygenase activity	1/2249	16/18639	0.0625	0.51798021342819	0.872321541628108	0.993405624712955
GO:0019841	retinol binding	1/2249	16/18639	0.0625	0.51798021342819	0.872321541628108	0.993405624712955
GO:0034450	ubiquitin-ubiquitin ligase activity	1/2249	16/18639	0.0625	0.51798021342819	0.872321541628108	0.993405624712955
GO:0043023	ribosomal large subunit binding	1/2249	16/18639	0.0625	0.51798021342819	0.872321541628108	0.993405624712955
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/2249	16/18639	0.0625	0.51798021342819	0.872321541628108	0.993405624712955
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/2249	16/18639	0.0625	0.51798021342819	0.872321541628108	0.993405624712955
GO:0140327	flippase activity	1/2249	16/18639	0.0625	0.51798021342819	0.872321541628108	0.993405624712955
GO:0035173	histone kinase activity	37/2249	360/18639	0.102777777777778	0.851789684304135	0.872932076660721	0.993405624712955
GO:0005201	extracellular matrix structural constituent	16/2249	168/18639	0.0952380952380952	0.789303182366766	0.874149549825624	0.993405624712955
GO:0016247	channel regulator activity	16/2249	168/18639	0.0952380952380952	0.789303182366766	0.874149549825624	0.993405624712955
GO:0016836	hydro-lyase activity	5/2249	61/18639	0.0819672131147541	0.679318312692708	0.874182587973806	0.993405624712955
GO:0061791	GTPase motor activity	3/2249	40/18639	0.075	0.621576256113828	0.876651640815216	0.993405624712955
GO:1990606	membrane scission GTPase motor activity	3/2249	40/18639	0.075	0.621576256113828	0.876651640815216	0.993405624712955
GO:0015108	chloride transmembrane transporter activity	11/2249	121/18639	0.0909090909090909	0.753425764986459	0.877559874989849	0.993405624712955
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	24/2249	243/18639	0.0987654320987654	0.818536633565535	0.877747322259244	0.993405624712955
GO:0005200	structural constituent of cytoskeleton	10/2249	112/18639	0.0892857142857143	0.739971733468843	0.882112407192361	0.993405624712955
GO:0141108	transporter regulator activity	16/2249	170/18639	0.0941176470588235	0.780017262574216	0.885046557134266	0.993405624712955
GO:0004676	3-phosphoinositide-dependent protein kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0004711	ribosomal protein S6 kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0035175	histone H3S10 kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0035979	histone H2AXS139 kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0044022	histone H3S28 kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0044023	histone H4S1 kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0044024	histone H2AS1 kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0044025	histone H2BS14 kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0072354	histone H3T3 kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0072371	histone H2AS121 kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0072518	Rho-dependent protein serine/threonine kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0140823	histone H2BS36 kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0140855	histone H3S57 kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0140995	histone H2A kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0140997	histone H4 kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0140998	histone H2B kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:1990244	histone H2AT120 kinase activity	24/2249	245/18639	0.0979591836734694	0.811854701862959	0.886770032586166	0.993405624712955
GO:0001727	lipid kinase activity	3/2249	41/18639	0.0731707317073171	0.606415859623247	0.88699436288137	0.993405624712955
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	3/2249	41/18639	0.0731707317073171	0.606415859623247	0.88699436288137	0.993405624712955
GO:0008227	G protein-coupled amine receptor activity	3/2249	41/18639	0.0731707317073171	0.606415859623247	0.88699436288137	0.993405624712955
GO:0016877	ligase activity, forming carbon-sulfur bonds	3/2249	41/18639	0.0731707317073171	0.606415859623247	0.88699436288137	0.993405624712955
GO:0008484	sulfuric ester hydrolase activity	1/2249	17/18639	0.0588235294117647	0.487510789108885	0.887740585438363	0.993405624712955
GO:0016805	dipeptidase activity	1/2249	17/18639	0.0588235294117647	0.487510789108885	0.887740585438363	0.993405624712955
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/2249	17/18639	0.0588235294117647	0.487510789108885	0.887740585438363	0.993405624712955
GO:0030548	acetylcholine receptor regulator activity	1/2249	17/18639	0.0588235294117647	0.487510789108885	0.887740585438363	0.993405624712955
GO:0045236	CXCR chemokine receptor binding	1/2249	17/18639	0.0588235294117647	0.487510789108885	0.887740585438363	0.993405624712955
GO:0070492	oligosaccharide binding	1/2249	17/18639	0.0588235294117647	0.487510789108885	0.887740585438363	0.993405624712955
GO:0140857	histone H3T45 kinase activity	24/2249	246/18639	0.0975609756097561	0.808554479497663	0.891081076193316	0.996086974472151
GO:0031267	small GTPase binding	28/2249	283/18639	0.0989399293286219	0.819982811363354	0.89168344842111	0.996086974472151
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	17/2249	181/18639	0.0939226519337017	0.778401204709767	0.892868184514911	0.996546119285274
GO:0035403	histone H3T6 kinase activity	24/2249	247/18639	0.097165991902834	0.805280979580668	0.895261462240927	0.998170410211668
GO:0051018	protein kinase A binding	4/2249	53/18639	0.0754716981132075	0.625485540743475	0.896379932511086	0.998170410211668
GO:0004679	AMP-activated protein kinase activity	24/2249	248/18639	0.0967741935483871	0.802033878856553	0.899313428352998	0.998170410211668
GO:0004706	JUN kinase kinase kinase activity	1/2249	18/18639	0.0555555555555556	0.460426856380614	0.901298281891436	0.998170410211668
GO:0008308	voltage-gated monoatomic anion channel activity	1/2249	18/18639	0.0555555555555556	0.460426856380614	0.901298281891436	0.998170410211668
GO:0015172	acidic amino acid transmembrane transporter activity	1/2249	18/18639	0.0555555555555556	0.460426856380614	0.901298281891436	0.998170410211668
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/2249	18/18639	0.0555555555555556	0.460426856380614	0.901298281891436	0.998170410211668
GO:0070064	proline-rich region binding	1/2249	18/18639	0.0555555555555556	0.460426856380614	0.901298281891436	0.998170410211668
GO:0099602	neurotransmitter receptor regulator activity	1/2249	18/18639	0.0555555555555556	0.460426856380614	0.901298281891436	0.998170410211668
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/2249	19/18639	0.0526315789473684	0.436193863939529	0.913219240165759	0.999999999995901
GO:0005229	intracellularly calcium-gated chloride channel activity	1/2249	19/18639	0.0526315789473684	0.436193863939529	0.913219240165759	0.999999999995901
GO:0005520	insulin-like growth factor binding	1/2249	19/18639	0.0526315789473684	0.436193863939529	0.913219240165759	0.999999999995901
GO:0034987	immunoglobulin receptor binding	1/2249	19/18639	0.0526315789473684	0.436193863939529	0.913219240165759	0.999999999995901
GO:0043395	heparan sulfate proteoglycan binding	1/2249	19/18639	0.0526315789473684	0.436193863939529	0.913219240165759	0.999999999995901
GO:0046527	glucosyltransferase activity	1/2249	19/18639	0.0526315789473684	0.436193863939529	0.913219240165759	0.999999999995901
GO:0141147	intracellularly calcium-gated channel activity	1/2249	19/18639	0.0526315789473684	0.436193863939529	0.913219240165759	0.999999999995901
GO:1990380	K48-linked deubiquitinase activity	1/2249	19/18639	0.0526315789473684	0.436193863939529	0.913219240165759	0.999999999995901
GO:0008234	cysteine-type peptidase activity	17/2249	187/18639	0.0909090909090909	0.753425764986459	0.918893788034301	0.999999999995901
GO:0140996	histone H3 kinase activity	35/2249	357/18639	0.0980392156862745	0.812517981848142	0.923547457254511	0.999999999995901
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/2249	20/18639	0.05	0.414384170742552	0.92370097640997	0.999999999995901
GO:0140939	histone H4 methyltransferase activity	1/2249	20/18639	0.05	0.414384170742552	0.92370097640997	0.999999999995901
GO:0035091	phosphatidylinositol binding	27/2249	284/18639	0.0950704225352113	0.787913564087951	0.926893960185135	0.999999999995901
GO:0008175	tRNA methyltransferase activity	2/2249	34/18639	0.0588235294117647	0.487510789108885	0.928637222320934	0.999999999995901
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/2249	34/18639	0.0588235294117647	0.487510789108885	0.928637222320934	0.999999999995901
GO:0016279	protein-lysine N-methyltransferase activity	5/2249	69/18639	0.072463768115942	0.600556769192105	0.930743997286865	0.999999999995901
GO:0005248	voltage-gated sodium channel activity	1/2249	21/18639	0.0476190476190476	0.394651591183383	0.932917180505462	0.999999999995901
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/2249	21/18639	0.0476190476190476	0.394651591183383	0.932917180505462	0.999999999995901
GO:0009975	cyclase activity	1/2249	21/18639	0.0476190476190476	0.394651591183383	0.932917180505462	0.999999999995901
GO:0015125	bile acid transmembrane transporter activity	1/2249	21/18639	0.0476190476190476	0.394651591183383	0.932917180505462	0.999999999995901
GO:0051428	peptide hormone receptor binding	1/2249	21/18639	0.0476190476190476	0.394651591183383	0.932917180505462	0.999999999995901
GO:0099095	ligand-gated monoatomic anion channel activity	3/2249	47/18639	0.0638297872340425	0.529001069033045	0.934251057747944	0.999999999995901
GO:0016278	lysine N-methyltransferase activity	5/2249	70/18639	0.0714285714285714	0.591977386775075	0.935919861220085	0.999999999995901
GO:0141003	histone H2AX kinase activity	34/2249	354/18639	0.096045197740113	0.795992192386824	0.939173303121098	0.999999999995901
GO:0005253	monoatomic anion channel activity	8/2249	103/18639	0.0776699029126214	0.643703566202023	0.940142775505461	0.999999999995901
GO:0033691	sialic acid binding	1/2249	22/18639	0.0454545454545455	0.376712882493229	0.941020589090875	0.999999999995901
GO:0034062	5'-3' RNA polymerase activity	1/2249	22/18639	0.0454545454545455	0.376712882493229	0.941020589090875	0.999999999995901
GO:0097747	RNA polymerase activity	1/2249	22/18639	0.0454545454545455	0.376712882493229	0.941020589090875	0.999999999995901
GO:0004190	aspartic-type endopeptidase activity	2/2249	36/18639	0.0555555555555556	0.460426856380614	0.942169288778676	0.999999999995901
GO:0016409	palmitoyltransferase activity	2/2249	36/18639	0.0555555555555556	0.460426856380614	0.942169288778676	0.999999999995901
GO:0045505	dynein intermediate chain binding	2/2249	36/18639	0.0555555555555556	0.460426856380614	0.942169288778676	0.999999999995901
GO:0008236	serine-type peptidase activity	17/2249	194/18639	0.0876288659793814	0.726240299239524	0.942391856706023	0.999999999995901
GO:0042379	chemokine receptor binding	5/2249	72/18639	0.0694444444444444	0.575533570475767	0.945242230735662	0.999999999995901
GO:0005254	chloride channel activity	6/2249	83/18639	0.072289156626506	0.599109644447063	0.945282299353227	0.999999999995901
GO:0005125	cytokine activity	21/2249	234/18639	0.0897435897435897	0.743766460307145	0.945722307595558	0.999999999995901
GO:0030551	cyclic nucleotide binding	2/2249	37/18639	0.0540540540540541	0.447982887289246	0.947983170240496	0.999999999995901
GO:0070001	aspartic-type peptidase activity	2/2249	37/18639	0.0540540540540541	0.447982887289246	0.947983170240496	0.999999999995901
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/2249	23/18639	0.0434782608695652	0.360334061515263	0.94814551228659	0.999999999995901
GO:0005212	structural constituent of eye lens	1/2249	23/18639	0.0434782608695652	0.360334061515263	0.94814551228659	0.999999999995901
GO:0016849	phosphorus-oxygen lyase activity	1/2249	23/18639	0.0434782608695652	0.360334061515263	0.94814551228659	0.999999999995901
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/2249	23/18639	0.0434782608695652	0.360334061515263	0.94814551228659	0.999999999995901
GO:0099186	structural constituent of postsynapse	1/2249	23/18639	0.0434782608695652	0.360334061515263	0.94814551228659	0.999999999995901
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	5/2249	73/18639	0.0684931506849315	0.5676495489624	0.949427548729354	0.999999999995901
GO:0017171	serine hydrolase activity	17/2249	198/18639	0.0858585858585859	0.711568778042766	0.953001921453427	0.999999999995901
GO:0005501	retinoid binding	2/2249	38/18639	0.0526315789473684	0.436193863939529	0.9532367617874	0.999999999995901
GO:0019840	isoprenoid binding	2/2249	38/18639	0.0526315789473684	0.436193863939529	0.9532367617874	0.999999999995901
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/2249	24/18639	0.0416666666666667	0.34532014228546	0.954410055844146	0.999999999995901
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/2249	24/18639	0.0416666666666667	0.34532014228546	0.954410055844146	0.999999999995901
GO:0004806	triacylglycerol lipase activity	1/2249	24/18639	0.0416666666666667	0.34532014228546	0.954410055844146	0.999999999995901
GO:0015149	hexose transmembrane transporter activity	1/2249	24/18639	0.0416666666666667	0.34532014228546	0.954410055844146	0.999999999995901
GO:0030552	cAMP binding	1/2249	24/18639	0.0416666666666667	0.34532014228546	0.954410055844146	0.999999999995901
GO:0055056	D-glucose transmembrane transporter activity	1/2249	24/18639	0.0416666666666667	0.34532014228546	0.954410055844146	0.999999999995901
GO:0070840	dynein complex binding	1/2249	24/18639	0.0416666666666667	0.34532014228546	0.954410055844146	0.999999999995901
GO:0005272	sodium channel activity	3/2249	51/18639	0.0588235294117647	0.487510789108885	0.954791522629476	0.999999999995901
GO:0022824	transmitter-gated monoatomic ion channel activity	4/2249	63/18639	0.0634920634920635	0.526202121577844	0.955060955645465	0.999999999995901
GO:0022835	transmitter-gated channel activity	4/2249	63/18639	0.0634920634920635	0.526202121577844	0.955060955645465	0.999999999995901
GO:0099106	ion channel regulator activity	13/2249	160/18639	0.08125	0.673374277456647	0.957734396929496	0.999999999995901
GO:0008170	N-methyltransferase activity	7/2249	98/18639	0.0714285714285714	0.591977386775075	0.959605030812266	0.999999999995901
GO:0000030	mannosyltransferase activity	1/2249	25/18639	0.04	0.331507336594042	0.959918075420107	0.999999999995901
GO:0004709	MAP kinase kinase kinase activity	1/2249	25/18639	0.04	0.331507336594042	0.959918075420107	0.999999999995901
GO:0005251	delayed rectifier potassium channel activity	1/2249	25/18639	0.04	0.331507336594042	0.959918075420107	0.999999999995901
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/2249	25/18639	0.04	0.331507336594042	0.959918075420107	0.999999999995901
GO:0019707	protein-cysteine S-acyltransferase activity	1/2249	25/18639	0.04	0.331507336594042	0.959918075420107	0.999999999995901
GO:0160215	deacylase activity	4/2249	65/18639	0.0615384615384615	0.510011287067757	0.962260535765656	0.999999999995901
GO:0015144	carbohydrate transmembrane transporter activity	2/2249	40/18639	0.05	0.414384170742552	0.962261025643162	0.999999999995901
GO:0071855	neuropeptide receptor binding	2/2249	40/18639	0.05	0.414384170742552	0.962261025643162	0.999999999995901
GO:0005543	phospholipid binding	48/2249	497/18639	0.096579476861167	0.800420128597284	0.962347731249942	0.999999999995901
GO:0017046	peptide hormone binding	3/2249	53/18639	0.0566037735849057	0.469114155557606	0.962644631262235	0.999999999995901
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/2249	26/18639	0.0384615384615385	0.318757054417348	0.964760895253575	0.999999999995901
GO:0005112	Notch binding	1/2249	26/18639	0.0384615384615385	0.318757054417348	0.964760895253575	0.999999999995901
GO:0005227	calcium-activated cation channel activity	1/2249	26/18639	0.0384615384615385	0.318757054417348	0.964760895253575	0.999999999995901
GO:0015145	monosaccharide transmembrane transporter activity	1/2249	26/18639	0.0384615384615385	0.318757054417348	0.964760895253575	0.999999999995901
GO:0034237	protein kinase A regulatory subunit binding	1/2249	26/18639	0.0384615384615385	0.318757054417348	0.964760895253575	0.999999999995901
GO:0140828	metal cation:monoatomic cation antiporter activity	2/2249	41/18639	0.0487804878048781	0.404277239748831	0.966120854502741	0.999999999995901
GO:0008307	structural constituent of muscle	2/2249	42/18639	0.0476190476190476	0.394651591183383	0.969599178151792	0.999999999995901
GO:0004252	serine-type endopeptidase activity	14/2249	176/18639	0.0795454545454545	0.659247544363151	0.969879077372745	0.999999999995901
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/2249	56/18639	0.0535714285714286	0.443983040081306	0.972054432627296	0.999999999995901
GO:0005242	inward rectifier potassium channel activity	1/2249	28/18639	0.0357142857142857	0.295988693387537	0.972762462161138	0.999999999995901
GO:0016866	intramolecular transferase activity	1/2249	28/18639	0.0357142857142857	0.295988693387537	0.972762462161138	0.999999999995901
GO:0051119	sugar transmembrane transporter activity	1/2249	28/18639	0.0357142857142857	0.295988693387537	0.972762462161138	0.999999999995901
GO:0051393	alpha-actinin binding	1/2249	28/18639	0.0357142857142857	0.295988693387537	0.972762462161138	0.999999999995901
GO:0016790	thiolester hydrolase activity	2/2249	44/18639	0.0454545454545455	0.376712882493229	0.97555150506414	0.999999999995901
GO:0004181	metallocarboxypeptidase activity	1/2249	29/18639	0.0344827586206897	0.285782186719002	0.976053914667699	0.999999999995901
GO:0016417	S-acyltransferase activity	1/2249	29/18639	0.0344827586206897	0.285782186719002	0.976053914667699	0.999999999995901
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	1/2249	29/18639	0.0344827586206897	0.285782186719002	0.976053914667699	0.999999999995901
GO:0004715	non-membrane spanning protein tyrosine kinase activity	2/2249	45/18639	0.0444444444444444	0.368341485104491	0.978088115517724	0.999999999995901
GO:0022839	monoatomic ion-gated channel activity	1/2249	30/18639	0.0333333333333333	0.276256113828368	0.978947775275563	0.999999999995901
GO:0031624	ubiquitin conjugating enzyme binding	1/2249	30/18639	0.0333333333333333	0.276256113828368	0.978947775275563	0.999999999995901
GO:0098918	structural constituent of synapse	1/2249	30/18639	0.0333333333333333	0.276256113828368	0.978947775275563	0.999999999995901
GO:0030276	clathrin binding	2/2249	46/18639	0.0434782608695652	0.360334061515263	0.980368871649728	0.999999999995901
GO:0005184	neuropeptide hormone activity	1/2249	31/18639	0.032258064516129	0.267344626285518	0.981492052421313	0.999999999995901
GO:0005249	voltage-gated potassium channel activity	6/2249	98/18639	0.0612244897959184	0.50740918866435	0.983099800808149	0.999999999995901
GO:0015106	bicarbonate transmembrane transporter activity	1/2249	32/18639	0.03125	0.258990106714095	0.983728959886084	0.999999999995901
GO:0160041	neuropeptide activity	1/2249	32/18639	0.03125	0.258990106714095	0.983728959886084	0.999999999995901
GO:0008188	neuropeptide receptor activity	2/2249	48/18639	0.0416666666666667	0.34532014228546	0.98425968472737	0.999999999995901
GO:0042923	neuropeptide binding	1/2249	33/18639	0.0303030303030303	0.251141921662153	0.985695615941128	0.999999999995901
GO:0099094	ligand-gated monoatomic cation channel activity	9/2249	136/18639	0.0661764705882353	0.548449637747496	0.987389852626752	0.999999999995901
GO:0015020	glucuronosyltransferase activity	1/2249	34/18639	0.0294117647058824	0.243755394554443	0.987424658172043	0.999999999995901
GO:0101005	deubiquitinase activity	7/2249	115/18639	0.0608695652173913	0.504467686121368	0.989027749385534	0.999999999995901
GO:0005246	calcium channel regulator activity	2/2249	53/18639	0.0377358490566038	0.312742770371738	0.990990011444799	0.999999999995901
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/2249	53/18639	0.0377358490566038	0.312742770371738	0.990990011444799	0.999999999995901
GO:0004497	monooxygenase activity	6/2249	106/18639	0.0566037735849057	0.469114155557606	0.991339845963428	0.999999999995901
GO:0030280	structural constituent of skin epidermis	1/2249	37/18639	0.027027027027027	0.223991443644623	0.991456172889743	0.999999999995901
GO:0015276	ligand-gated monoatomic ion channel activity	13/2249	186/18639	0.0698924731182796	0.579246690285288	0.991726538316671	0.999999999995901
GO:0046873	metal ion transmembrane transporter activity	39/2249	450/18639	0.0866666666666667	0.718265895953757	0.991896814530402	0.999999999995901
GO:0098960	postsynaptic neurotransmitter receptor activity	3/2249	69/18639	0.0434782608695652	0.360334061515263	0.992417103829826	0.999999999995901
GO:0004843	cysteine-type deubiquitinase activity	6/2249	108/18639	0.0555555555555556	0.460426856380614	0.992701743810486	0.999999999995901
GO:0022834	ligand-gated channel activity	13/2249	188/18639	0.0691489361702128	0.573084491452466	0.992770922496103	0.999999999995901
GO:0030594	neurotransmitter receptor activity	5/2249	97/18639	0.0515463917525773	0.42720017602325	0.993547191438753	0.999999999995901
GO:0005267	potassium channel activity	7/2249	124/18639	0.0564516129032258	0.467853095999656	0.994753364893643	0.999999999995901
GO:0005261	monoatomic cation channel activity	27/2249	341/18639	0.0791788856304985	0.65620953724627	0.99509710359496	0.999999999995901
GO:0015079	potassium ion transmembrane transporter activity	10/2249	160/18639	0.0625	0.51798021342819	0.995102257123482	0.999999999995901
GO:0019783	ubiquitin-like protein peptidase activity	7/2249	127/18639	0.0551181102362205	0.456801448062656	0.995923265787607	0.999999999995901
GO:0005262	calcium channel activity	7/2249	131/18639	0.0534351145038168	0.442853312243949	0.997101147477567	0.999999999995901
GO:0005216	monoatomic ion channel activity	36/2249	448/18639	0.0803571428571429	0.665974560121959	0.997887750257505	0.999999999995901
GO:0001653	peptide receptor activity	6/2249	128/18639	0.046875	0.388485160071143	0.998775850437966	0.999999999995901
GO:0022836	gated channel activity	22/2249	318/18639	0.0691823899371069	0.573361745681519	0.999139896980989	0.999999999995901
GO:0015085	calcium ion transmembrane transporter activity	7/2249	147/18639	0.0476190476190476	0.394651591183383	0.999293277573187	0.999999999995901
GO:0022843	voltage-gated monoatomic cation channel activity	6/2249	143/18639	0.041958041958042	0.347734968455289	0.999702173012124	0.999999999995901
GO:0022832	voltage-gated channel activity	8/2249	175/18639	0.0457142857142857	0.378865527536048	0.999818549550098	0.999999999995901
GO:0008528	G protein-coupled peptide receptor activity	4/2249	122/18639	0.0327868852459016	0.271727325077083	0.999863421412108	0.999999999995901
GO:0005244	voltage-gated monoatomic ion channel activity	7/2249	173/18639	0.0404624277456647	0.335339791352354	0.999937682705228	0.999999999995901
GO:0030527	structural constituent of chromatin	1/2249	98/18639	0.0102040816326531	0.0845681981107249	0.999996748613572	0.999999999995901
GO:0045182	translation regulator activity	14/2249	356/18639	0.0393258426966292	0.325920134291895	0.999999983450796	0.999999999995901
GO:0030371	translation repressor activity	7/2249	329/18639	0.0212765957446809	0.176333689677682	0.999999999995901	0.999999999995901