ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0004674	protein serine/threonine kinase activity	144/3556	433/18639	0.33256351039261	1.743152775649	1.0303385771233e-12	1.3755020004596e-09
GO:0003712	transcription coregulator activity	156/3556	495/18639	0.315151515151515	1.65188669598118	1.43845834696212e-11	9.60170946597214e-09
GO:0045296	cadherin binding	114/3556	334/18639	0.341317365269461	1.78903666233338	3.90588180326672e-11	1.73811740245369e-08
GO:0030695	GTPase regulator activity	151/3556	489/18639	0.30879345603272	1.6185605250264	1.61894775794751e-10	5.09152480453138e-08
GO:0060589	nucleoside-triphosphatase regulator activity	151/3556	490/18639	0.308163265306122	1.61525734028144	1.90693812903797e-10	5.09152480453138e-08
GO:0106310	protein serine kinase activity	116/3556	361/18639	0.321329639889197	1.68426972944171	1.68720984631896e-09	3.75404190805969e-07
GO:0005085	guanyl-nucleotide exchange factor activity	81/3556	230/18639	0.352173913043478	1.84594194747396	5.06467814193813e-09	9.65906474212486e-07
GO:0031267	small GTPase binding	94/3556	283/18639	0.332155477031802	1.74101404285595	9.41403394536072e-09	1.57096691463207e-06
GO:0003713	transcription coactivator activity	85/3556	256/18639	0.33203125	1.74036289897357	4.82820236874984e-08	7.1618335136456e-06
GO:0051020	GTPase binding	99/3556	315/18639	0.314285714285714	1.6473485457175	8.78900009582965e-08	1.02176329406864e-05
GO:0035173	histone kinase activity	110/3556	360/18639	0.305555555555556	1.60158886389201	9.01649410931214e-08	1.02176329406864e-05
GO:0004679	AMP-activated protein kinase activity	82/3556	248/18639	0.330645161290323	1.73309762690954	1.0139815769335e-07	1.02176329406864e-05
GO:0140996	histone H3 kinase activity	109/3556	357/18639	0.305322128851541	1.60036534298759	1.07592495147603e-07	1.02176329406864e-05
GO:0141003	histone H2AX kinase activity	108/3556	354/18639	0.305084745762712	1.59912108444072	1.28375264867835e-07	1.02176329406864e-05
GO:0004677	DNA-dependent protein kinase activity	81/3556	246/18639	0.329268292682927	1.7258806825976	1.47788648974477e-07	1.02176329406864e-05
GO:0140857	histone H3T45 kinase activity	81/3556	246/18639	0.329268292682927	1.7258806825976	1.47788648974477e-07	1.02176329406864e-05
GO:0035402	histone H3T11 kinase activity	81/3556	247/18639	0.327935222672065	1.718893311413	1.79277621128006e-07	1.02176329406864e-05
GO:0004676	3-phosphoinositide-dependent protein kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0004711	ribosomal protein S6 kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0035175	histone H3S10 kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0035979	histone H2AXS139 kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0044022	histone H3S28 kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0044023	histone H4S1 kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0044024	histone H2AS1 kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0044025	histone H2BS14 kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0072354	histone H3T3 kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0072371	histone H2AS121 kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0072518	Rho-dependent protein serine/threonine kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0140823	histone H2BS36 kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0140855	histone H3S57 kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0140995	histone H2A kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0140997	histone H4 kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0140998	histone H2B kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:1990244	histone H2AT120 kinase activity	80/3556	245/18639	0.326530612244898	1.71153095658961	2.60224359538081e-07	1.02176329406864e-05
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	79/3556	243/18639	0.325102880658436	1.70404741074032	3.76906857291935e-07	1.40599394577173e-05
GO:0035403	histone H3T6 kinase activity	80/3556	247/18639	0.323886639676113	1.69767240633382	3.79144434814848e-07	1.40599394577173e-05
GO:0004842	ubiquitin-protein transferase activity	128/3556	449/18639	0.285077951002227	1.49425419818068	6.30823030956488e-07	2.27607769277543e-05
GO:0038024	cargo receptor activity	29/3556	65/18639	0.446153846153846	2.33854373972484	2.21652908200192e-06	7.78701664334886e-05
GO:0019787	ubiquitin-like protein transferase activity	132/3556	479/18639	0.275574112734864	1.44443922589008	3.0547683957873e-06	0.000104567072009642
GO:0016755	aminoacyltransferase activity	135/3556	496/18639	0.272177419354839	1.42663524166334	4.78179925608002e-06	0.000159592550171671
GO:0140297	DNA-binding transcription factor binding	133/3556	488/18639	0.272540983606557	1.42854088679489	5.21035243593973e-06	0.000169654158584867
GO:0035091	phosphatidylinositol binding	85/3556	284/18639	0.299295774647887	1.56877782442688	6.21563163246151e-06	0.000197568291174669
GO:0004559	alpha-mannosidase activity	11/3556	15/18639	0.733333333333333	3.84381327334083	7.64547038495293e-06	0.00023736518520726
GO:0061630	ubiquitin protein ligase activity	100/3556	353/18639	0.28328611898017	1.48486219675798	1.36655859410618e-05	0.000414626300711762
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	26/3556	60/18639	0.433333333333333	2.27134420697413	1.39807003577963e-05	0.000414760777281291
GO:0005096	GTPase activator activity	80/3556	271/18639	0.29520295202952	1.54732503455518	1.98831332218183e-05	0.000568917067424281
GO:0015923	mannosidase activity	11/3556	16/18639	0.6875	3.60357494375703	2.02230363199915e-05	0.000568917067424281
GO:1901981	phosphatidylinositol phosphate binding	59/3556	185/18639	0.318918918918919	1.6716337822637	2.0455445120873e-05	0.000568917067424281
GO:0061659	ubiquitin-like protein ligase activity	103/3556	372/18639	0.276881720430108	1.45129313472913	2.89566649568185e-05	0.000788921381986791
GO:0019838	growth factor binding	46/3556	136/18639	0.338235294117647	1.77288179051148	3.18823235746931e-05	0.000851258039444305
GO:0015924	mannosyl-oligosaccharide mannosidase activity	8/3556	10/18639	0.8	4.19325084364454	5.41864880447678e-05	0.00141841101058363
GO:0003714	transcription corepressor activity	62/3556	204/18639	0.303921568627451	1.59302421756104	6.45449659602592e-05	0.00165706787609512
GO:0005160	transforming growth factor beta receptor binding	14/3556	26/18639	0.538461538461538	2.82238037552998	7.78422744111381e-05	0.00196074408186546
GO:0008013	beta-catenin binding	37/3556	106/18639	0.349056603773585	1.82960237281661	8.64316558490661e-05	0.00213348381617933
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	33/3556	91/18639	0.362637362637363	1.90078678352019	8.78963369961522e-05	0.00213348381617933
GO:0004402	histone acetyltransferase activity	19/3556	42/18639	0.452380952380952	2.37118351277519	9.76482549346515e-05	0.00232786464888857
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	95/3556	349/18639	0.272206303724928	1.4267866409249	0.000115154458249279	0.00269703862741733
GO:0005385	zinc ion transmembrane transporter activity	14/3556	27/18639	0.518518518518518	2.71784776902887	0.000133338167089111	0.00306907677696489
GO:0034212	protein N-acetyltransferase activity	22/3556	53/18639	0.415094339622642	2.1757433622684	0.00013699152311542	0.00309972344676417
GO:0005114	type II transforming growth factor beta receptor binding	8/3556	11/18639	0.727272727272727	3.81204622149504	0.000165222304351963	0.00367619627183119
GO:0140030	modification-dependent protein binding	53/3556	173/18639	0.30635838150289	1.60579692711821	0.000168676354792484	0.00369152350242567
GO:0061733	protein-lysine-acetyltransferase activity	20/3556	47/18639	0.425531914893617	2.23045257640667	0.000182064589148315	0.00392026171795161
GO:0005543	phospholipid binding	127/3556	497/18639	0.255533199195171	1.33939350388043	0.000196302547328287	0.00411915936174643
GO:0003779	actin binding	115/3556	443/18639	0.259593679458239	1.36067676924132	0.000198903041622632	0.00411915936174643
GO:0000149	SNARE binding	36/3556	106/18639	0.339622641509434	1.78015366003778	0.000200558320983909	0.00411915936174643
GO:0017124	SH3 domain binding	38/3556	115/18639	0.330434782608696	1.73199491367927	0.000256456161966955	0.00518740873069523
GO:0046030	inositol trisphosphate phosphatase activity	9/3556	14/18639	0.642857142857143	3.36957657078579	0.000260911311990538	0.00519875524637864
GO:0070412	R-SMAD binding	13/3556	26/18639	0.5	2.62078177727784	0.000369387589233355	0.00725194752391954
GO:0016758	hexosyltransferase activity	57/3556	197/18639	0.289340101522843	1.51659453101357	0.000506259496904211	0.00979502070097279
GO:0016757	glycosyltransferase activity	73/3556	267/18639	0.273408239700375	1.43308666472871	0.000584342834069878	0.0111442526211898
GO:0140033	acetylation-dependent protein binding	12/3556	24/18639	0.5	2.62078177727784	0.000621745396671623	0.0116905648529101
GO:0004445	inositol-polyphosphate 5-phosphatase activity	7/3556	10/18639	0.7	3.66909448818898	0.000637022842507081	0.0118114652048188
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	64/3556	229/18639	0.279475982532751	1.46489112441731	0.000664598686236744	0.0121170669970269
GO:0001223	transcription coactivator binding	18/3556	44/18639	0.409090909090909	2.14427599959096	0.000671657646277144	0.0121170669970269
GO:0032266	phosphatidylinositol-3-phosphate binding	19/3556	48/18639	0.395833333333333	2.07478557367829	0.000781494859769484	0.0139106085038968
GO:0051011	microtubule minus-end binding	8/3556	13/18639	0.615384615384615	3.22557757203427	0.000892667158692156	0.0156804033796583
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	13/3556	28/18639	0.464285714285714	2.43358307890085	0.000908011083115783	0.0157427895579165
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	9/3556	16/18639	0.5625	2.94837949943757	0.00102885598858096	0.0176092659584049
GO:0010485	histone H4 acetyltransferase activity	15/3556	35/18639	0.428571428571429	2.24638438052386	0.00104894489193506	0.0177258408953583
GO:1902936	phosphatidylinositol bisphosphate binding	35/3556	111/18639	0.315315315315315	1.65274526494999	0.00114485412827051	0.0191047532655141
GO:1990841	promoter-specific chromatin binding	24/3556	68/18639	0.352941176470588	1.84996360749024	0.00119570008950876	0.0197069088826444
GO:0010484	histone H3 acetyltransferase activity	13/3556	29/18639	0.448275862068966	2.34966642100772	0.00136060228102416	0.0221512688435031
GO:0016407	acetyltransferase activity	31/3556	96/18639	0.322916666666667	1.69258823115861	0.00139015475936494	0.0223597181174963
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	7/3556	11/18639	0.636363636363636	3.33554044380816	0.00146267378427854	0.0229484096552434
GO:0004712	protein serine/threonine/tyrosine kinase activity	17/3556	43/18639	0.395348837209302	2.07224605645225	0.00147832451711681	0.0229484096552434
GO:0048156	tau protein binding	17/3556	43/18639	0.395348837209302	2.07224605645225	0.00147832451711681	0.0229484096552434
GO:0008080	N-acetyltransferase activity	24/3556	69/18639	0.347826086956522	1.82315254071502	0.00150646718740622	0.0230676084681232
GO:0052742	phosphatidylinositol kinase activity	12/3556	26/18639	0.461538461538462	2.4191831790257	0.00152056145707479	0.0230676084681232
GO:0070577	lysine-acetylated histone binding	11/3556	23/18639	0.478260869565217	2.50683474348315	0.00166704844366332	0.0250057266549498
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	8/3556	14/18639	0.571428571428571	2.99517917403182	0.00173500828762765	0.0257359562664768
GO:0031418	L-ascorbic acid binding	10/3556	20/18639	0.5	2.62078177727784	0.00177771304623536	0.0257961621383066
GO:0052745	inositol phosphate phosphatase activity	10/3556	20/18639	0.5	2.62078177727784	0.00177771304623536	0.0257961621383066
GO:0048029	monosaccharide binding	25/3556	74/18639	0.337837837837838	1.7707984981607	0.00193525402464657	0.0276133940529192
GO:0043995	histone H4K5 acetyltransferase activity	13/3556	30/18639	0.433333333333333	2.27134420697413	0.00198568226897396	0.0276133940529192
GO:0043996	histone H4K8 acetyltransferase activity	13/3556	30/18639	0.433333333333333	2.27134420697413	0.00198568226897396	0.0276133940529192
GO:0043997	histone H4K12 acetyltransferase activity	13/3556	30/18639	0.433333333333333	2.27134420697413	0.00198568226897396	0.0276133940529192
GO:0019903	protein phosphatase binding	42/3556	144/18639	0.291666666666667	1.52878937007874	0.00218830018077921	0.0301173272303117
GO:0004713	protein tyrosine kinase activity	41/3556	140/18639	0.292857142857143	1.53502932669131	0.00225683633731558	0.0302530965197444
GO:0001221	transcription coregulator binding	35/3556	115/18639	0.304347826086957	1.59525847312564	0.00225784528741457	0.0302530965197444
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	12/3556	27/18639	0.444444444444444	2.32958380202475	0.00226614955204078	0.0302530965197444
GO:0052866	phosphatidylinositol phosphate phosphatase activity	14/3556	34/18639	0.411764705882353	2.15829087540528	0.00242059120941825	0.0319949432135976
GO:0043998	histone H2A acetyltransferase activity	11/3556	24/18639	0.458333333333333	2.40238329583802	0.00255153563727169	0.0330708745219194
GO:0070300	phosphatidic acid binding	11/3556	24/18639	0.458333333333333	2.40238329583802	0.00255153563727169	0.0330708745219194
GO:0046915	transition metal ion transmembrane transporter activity	17/3556	45/18639	0.377777777777778	1.98014623172103	0.00263245637349425	0.033791627486681
GO:0016922	nuclear receptor binding	40/3556	137/18639	0.291970802919708	1.5303835195783	0.00269011246964803	0.0342028585426678
GO:0031543	peptidyl-proline dioxygenase activity	7/3556	12/18639	0.583333333333333	3.05757874015748	0.00293303985750905	0.0365944692502297
GO:0097677	STAT family protein binding	7/3556	12/18639	0.583333333333333	3.05757874015748	0.00293303985750905	0.0365944692502297
GO:0019902	phosphatase binding	52/3556	190/18639	0.273684210526316	1.43453318335208	0.00324798440745804	0.0397987442411316
GO:0004620	phospholipase activity	33/3556	109/18639	0.302752293577982	1.58689538807649	0.00325015996509689	0.0397987442411316
GO:0036408	histone H3K14 acetyltransferase activity	12/3556	28/18639	0.428571428571429	2.24638438052386	0.00328475340373453	0.0397987442411316
GO:0016298	lipase activity	38/3556	130/18639	0.292307692307692	1.53214934671628	0.00330910907173454	0.0397987442411316
GO:0051213	dioxygenase activity	29/3556	93/18639	0.311827956989247	1.63446605464639	0.00348384818656633	0.0412357897778783
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	28/3556	89/18639	0.314606741573034	1.64903123064673	0.00352125845294242	0.0412357897778783
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	28/3556	89/18639	0.314606741573034	1.64903123064673	0.00352125845294242	0.0412357897778783
GO:0008483	transaminase activity	11/3556	25/18639	0.44	2.3062879640045	0.00377904543422605	0.0434036571310614
GO:0043425	bHLH transcription factor binding	13/3556	32/18639	0.40625	2.12938519403825	0.00394326453012237	0.0434036571310614
GO:0042578	phosphoric ester hydrolase activity	90/3556	363/18639	0.247933884297521	1.29956121187331	0.00395555049528472	0.0434036571310614
GO:0140793	histone H2AXY142 phosphatase activity	28/3556	90/18639	0.311111111111111	1.63070866141732	0.00419828806185128	0.0434036571310614
GO:0032931	histone H3K56 acetyltransferase activity	10/3556	22/18639	0.454545454545455	2.3825288884344	0.0042915975590263	0.0434036571310614
GO:0043992	histone H3K9 acetyltransferase activity	10/3556	22/18639	0.454545454545455	2.3825288884344	0.0042915975590263	0.0434036571310614
GO:0043993	histone H3K18 acetyltransferase activity	10/3556	22/18639	0.454545454545455	2.3825288884344	0.0042915975590263	0.0434036571310614
GO:0043994	histone H3K23 acetyltransferase activity	10/3556	22/18639	0.454545454545455	2.3825288884344	0.0042915975590263	0.0434036571310614
GO:0043999	histone H2AK5 acetyltransferase activity	10/3556	22/18639	0.454545454545455	2.3825288884344	0.0042915975590263	0.0434036571310614
GO:0044012	histone H2AK9 acetyltransferase activity	10/3556	22/18639	0.454545454545455	2.3825288884344	0.0042915975590263	0.0434036571310614
GO:0044014	histone H2BK5 acetyltransferase activity	10/3556	22/18639	0.454545454545455	2.3825288884344	0.0042915975590263	0.0434036571310614
GO:0044015	histone H2BK12 acetyltransferase activity	10/3556	22/18639	0.454545454545455	2.3825288884344	0.0042915975590263	0.0434036571310614
GO:0044016	histone H3K4 acetyltransferase activity	10/3556	22/18639	0.454545454545455	2.3825288884344	0.0042915975590263	0.0434036571310614
GO:0044017	histone H3K27 acetyltransferase activity	10/3556	22/18639	0.454545454545455	2.3825288884344	0.0042915975590263	0.0434036571310614
GO:0044018	histone H3K36 acetyltransferase activity	10/3556	22/18639	0.454545454545455	2.3825288884344	0.0042915975590263	0.0434036571310614
GO:0046972	histone H4K16 acetyltransferase activity	10/3556	22/18639	0.454545454545455	2.3825288884344	0.0042915975590263	0.0434036571310614
GO:0050321	tau-protein kinase activity	10/3556	22/18639	0.454545454545455	2.3825288884344	0.0042915975590263	0.0434036571310614
GO:0140908	histone H3K122 acetyltransferase activity	10/3556	22/18639	0.454545454545455	2.3825288884344	0.0042915975590263	0.0434036571310614
GO:0140359	ABC-type transporter activity	17/3556	47/18639	0.361702127659574	1.89588468994567	0.00445234316078343	0.0446908129296683
GO:0016409	palmitoyltransferase activity	14/3556	36/18639	0.388888888888889	2.03838582677165	0.00451282482352807	0.0449598592493282
GO:0042393	histone binding	64/3556	247/18639	0.259109311740891	1.35813792506706	0.00487839471942694	0.0475905277723608
GO:0008374	O-acyltransferase activity	19/3556	55/18639	0.345454545454545	1.81072195521014	0.00488649526820422	0.0475905277723608
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	6/3556	10/18639	0.6	3.14493813273341	0.00496971337610158	0.0475905277723608
GO:0008239	dipeptidyl-peptidase activity	6/3556	10/18639	0.6	3.14493813273341	0.00496971337610158	0.0475905277723608
GO:0016303	1-phosphatidylinositol-3-kinase activity	6/3556	10/18639	0.6	3.14493813273341	0.00496971337610158	0.0475905277723608
GO:0030331	nuclear estrogen receptor binding	15/3556	40/18639	0.375	1.96558633295838	0.00499076695740113	0.0475905277723608
GO:0046332	SMAD binding	25/3556	79/18639	0.316455696202532	1.65872264384673	0.00517433013564032	0.0489909980927647
GO:0030246	carbohydrate binding	71/3556	280/18639	0.253571428571429	1.32911075847662	0.00553657847779883	0.0520516356891651
GO:0016798	hydrolase activity, acting on glycosyl bonds	37/3556	130/18639	0.284615384615385	1.49182962706585	0.0059974855433155	0.0559905118903929
GO:0044013	histone H2B acetyltransferase activity	10/3556	23/18639	0.434782608695652	2.27894067589377	0.00631048149392087	0.0585034221832247
GO:0016769	transferase activity, transferring nitrogenous groups	12/3556	30/18639	0.4	2.09662542182227	0.00641450803009692	0.05865320698753
GO:0051721	protein phosphatase 2A binding	12/3556	30/18639	0.4	2.09662542182227	0.00641450803009692	0.05865320698753
GO:0001727	lipid kinase activity	15/3556	41/18639	0.365853658536585	1.91764520288622	0.00650542227657537	0.0590798553688987
GO:0019207	kinase regulator activity	72/3556	287/18639	0.250871080139373	1.31495671055055	0.00686747546522974	0.0619464847708223
GO:0001618	virus receptor activity	25/3556	81/18639	0.308641975308642	1.61776652918385	0.00736368749539292	0.0658906079622184
GO:1901505	carbohydrate derivative transmembrane transporter activity	18/3556	53/18639	0.339622641509434	1.78015366003778	0.00740343909687847	0.0658906079622184
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	114/3556	484/18639	0.235537190082645	1.23458315127964	0.00760036399388726	0.0664744960570849
GO:0005044	scavenger receptor activity	11/3556	27/18639	0.407407407407407	2.13545181852268	0.00761403527495306	0.0664744960570849
GO:0019905	syntaxin binding	20/3556	61/18639	0.327868852459016	1.71854542772317	0.00761842539081198	0.0664744960570849
GO:0004725	protein tyrosine phosphatase activity	29/3556	98/18639	0.295918367346939	1.55107492940933	0.00786948073768255	0.068219199901339
GO:0017147	Wnt-protein binding	12/3556	31/18639	0.387096774193548	2.02899234369897	0.00867895596586029	0.0741921332023803
GO:0140272	exogenous protein binding	25/3556	82/18639	0.304878048780488	1.59803766907185	0.00871486323811132	0.0741921332023803
GO:0001216	DNA-binding transcription activator activity	115/3556	491/18639	0.234215885947047	1.22765745167801	0.00879036866574368	0.0741921332023803
GO:0019199	transmembrane receptor protein kinase activity	24/3556	78/18639	0.307692307692308	1.61278878601713	0.00888801340584766	0.0741921332023803
GO:0032454	histone H3K9 demethylase activity	7/3556	14/18639	0.5	2.62078177727784	0.00889194105796319	0.0741921332023803
GO:0042813	Wnt receptor activity	7/3556	14/18639	0.5	2.62078177727784	0.00889194105796319	0.0741921332023803
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	6/3556	11/18639	0.545454545454545	2.85903466612128	0.00917816088628923	0.0756348443407168
GO:0048185	activin binding	6/3556	11/18639	0.545454545454545	2.85903466612128	0.00917816088628923	0.0756348443407168
GO:0035591	signaling adaptor activity	36/3556	129/18639	0.27906976744186	1.46276192220159	0.00925590827590502	0.0758075923210626
GO:0016791	phosphatase activity	68/3556	273/18639	0.249084249084249	1.30559092201387	0.00994253209994277	0.0809346363013634
GO:0019887	protein kinase regulator activity	64/3556	255/18639	0.250980392156863	1.3155296764375	0.0102235969866194	0.0827181938008297
GO:0046966	nuclear thyroid hormone receptor binding	11/3556	28/18639	0.392857142857143	2.05918568214687	0.010415335309271	0.0836286844352473
GO:1990782	protein tyrosine kinase binding	33/3556	117/18639	0.282051282051282	1.4783897205157	0.0104614159555703	0.0836286844352473
GO:0043130	ubiquitin binding	29/3556	100/18639	0.29	1.52005343082115	0.0105864300216482	0.0841243099934542
GO:0140938	histone H3 methyltransferase activity	16/3556	47/18639	0.340425531914894	1.78436206112534	0.0109507198016548	0.0865042067172141
GO:0042054	histone methyltransferase activity	21/3556	67/18639	0.313432835820896	1.64287812903984	0.0110878113289056	0.0870221495776145
GO:0016741	transferase activity, transferring one-carbon groups	55/3556	215/18639	0.255813953488372	1.34086509535145	0.011146657361627	0.0870221495776145
GO:0019955	cytokine binding	39/3556	144/18639	0.270833333333333	1.41959012935883	0.0116967446673119	0.0907857798305896
GO:0016854	racemase and epimerase activity	8/3556	18/18639	0.444444444444444	2.32958380202475	0.0122465265411366	0.0945035429619497
GO:0140034	methylation-dependent protein binding	23/3556	76/18639	0.302631578947368	1.58626265466817	0.0126764837091014	0.0972592284577604
GO:0005518	collagen binding	22/3556	72/18639	0.305555555555556	1.60158886389201	0.0129676343075637	0.0989245245748433
GO:0008194	UDP-glycosyltransferase activity	39/3556	145/18639	0.268965517241379	1.40979985260463	0.0131252511941813	0.0995580133194998
GO:0005548	phospholipid transporter activity	21/3556	68/18639	0.308823529411765	1.61871815655396	0.013224922974406	0.0997473004001809
GO:0001046	core promoter sequence-specific DNA binding	15/3556	44/18639	0.340909090909091	1.7868966663258	0.0133434033907006	0.100075525430254
GO:0004629	phospholipase C activity	11/3556	29/18639	0.379310344827586	1.98817927931422	0.0139428871659295	0.103543866644992
GO:0015929	hexosaminidase activity	7/3556	15/18639	0.466666666666667	2.44606299212598	0.0139609707835944	0.103543866644992
GO:0051015	actin filament binding	53/3556	209/18639	0.253588516746411	1.32920032723182	0.0148475157985004	0.109510682823193
GO:0032182	ubiquitin-like protein binding	33/3556	120/18639	0.275	1.44142997750281	0.0153549937841335	0.111902616068574
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	6/3556	12/18639	0.5	2.62078177727784	0.0154232819150694	0.111902616068574
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	6/3556	12/18639	0.5	2.62078177727784	0.0154232819150694	0.111902616068574
GO:0002039	p53 binding	21/3556	69/18639	0.304347826086957	1.59525847312564	0.0156761972817025	0.113122829032826
GO:0008276	protein methyltransferase activity	27/3556	95/18639	0.284210526315789	1.48970753655793	0.0174013907959706	0.124897079100112
GO:0003756	protein disulfide isomerase activity	8/3556	19/18639	0.421052631578947	2.20697412823397	0.0176760769953897	0.125518951004496
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	8/3556	19/18639	0.421052631578947	2.20697412823397	0.0176760769953897	0.125518951004496
GO:0035064	methylated histone binding	22/3556	74/18639	0.297297297297297	1.55830267838142	0.0179473987385084	0.126771308549782
GO:0030295	protein kinase activator activity	37/3556	139/18639	0.266187050359712	1.39523634186015	0.0180807314410402	0.127040928809414
GO:0032452	histone demethylase activity	11/3556	30/18639	0.366666666666667	1.92190663667042	0.0183014224550959	0.127918319254204
GO:0043531	ADP binding	13/3556	38/18639	0.342105263157895	1.7931664791901	0.0199030687131401	0.13686886845552
GO:0035198	miRNA binding	14/3556	42/18639	0.333333333333333	1.74718785151856	0.0202404797044018	0.13686886845552
GO:0030276	clathrin binding	15/3556	46/18639	0.326086956521739	1.70920550692033	0.0203543444729782	0.13686886845552
GO:0008171	O-methyltransferase activity	9/3556	23/18639	0.391304347826087	2.0510466083044	0.020402175897115	0.13686886845552
GO:0017134	fibroblast growth factor binding	9/3556	23/18639	0.391304347826087	2.0510466083044	0.020402175897115	0.13686886845552
GO:0042171	lysophosphatidic acid acyltransferase activity	9/3556	23/18639	0.391304347826087	2.0510466083044	0.020402175897115	0.13686886845552
GO:0071617	lysophospholipid acyltransferase activity	9/3556	23/18639	0.391304347826087	2.0510466083044	0.020402175897115	0.13686886845552
GO:0140103	catalytic activity, acting on a glycoprotein	9/3556	23/18639	0.391304347826087	2.0510466083044	0.020402175897115	0.13686886845552
GO:0004707	MAP kinase activity	7/3556	16/18639	0.4375	2.29318405511811	0.0207994250284658	0.137461546599019
GO:0005024	transforming growth factor beta receptor activity	7/3556	16/18639	0.4375	2.29318405511811	0.0207994250284658	0.137461546599019
GO:0015562	efflux transmembrane transporter activity	7/3556	16/18639	0.4375	2.29318405511811	0.0207994250284658	0.137461546599019
GO:0042826	histone deacetylase binding	34/3556	127/18639	0.267716535433071	1.4032532350779	0.0209063075551978	0.137487293528025
GO:0140299	molecular sensor activity	21/3556	71/18639	0.295774647887324	1.55032161472774	0.0216386525919683	0.141605888285675
GO:0070273	phosphatidylinositol-4-phosphate binding	11/3556	31/18639	0.354838709677419	1.85990964839073	0.0235937790241754	0.152901432025603
GO:0140457	protein demethylase activity	11/3556	31/18639	0.354838709677419	1.85990964839073	0.0235937790241754	0.152901432025603
GO:0015293	symporter activity	38/3556	146/18639	0.26027397260274	1.36424256899394	0.023714665859349	0.152942410252323
GO:0043560	insulin receptor substrate binding	6/3556	13/18639	0.461538461538462	2.4191831790257	0.0240888309798757	0.153868848603512
GO:0046974	histone H3K9 methyltransferase activity	6/3556	13/18639	0.461538461538462	2.4191831790257	0.0240888309798757	0.153868848603512
GO:0005154	epidermal growth factor receptor binding	12/3556	35/18639	0.342857142857143	1.79710750441909	0.0243749325991291	0.154954928665892
GO:0015095	magnesium ion transmembrane transporter activity	8/3556	20/18639	0.4	2.09662542182227	0.0246347661490039	0.155864515682086
GO:0043495	protein-membrane adaptor activity	15/3556	47/18639	0.319148936170213	1.672839432305	0.0247622935376611	0.155932367324422
GO:0030971	receptor tyrosine kinase binding	23/3556	81/18639	0.283950617283951	1.48834520684914	0.0269572080118584	0.164536261427438
GO:0016410	N-acyltransferase activity	26/3556	94/18639	0.276595744680851	1.44979417466434	0.0270304173074795	0.164536261427438
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	5/3556	10/18639	0.5	2.62078177727784	0.0270477670700711	0.164536261427438
GO:0005345	purine nucleobase transmembrane transporter activity	5/3556	10/18639	0.5	2.62078177727784	0.0270477670700711	0.164536261427438
GO:0031720	haptoglobin binding	5/3556	10/18639	0.5	2.62078177727784	0.0270477670700711	0.164536261427438
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	5/3556	10/18639	0.5	2.62078177727784	0.0270477670700711	0.164536261427438
GO:0140999	histone H3K4 trimethyltransferase activity	5/3556	10/18639	0.5	2.62078177727784	0.0270477670700711	0.164536261427438
GO:0015294	solute:monoatomic cation symporter activity	31/3556	116/18639	0.267241379310345	1.40076267406229	0.0271145898981545	0.164536261427438
GO:0004622	lysophospholipase activity	9/3556	24/18639	0.375	1.96558633295838	0.0272462157433247	0.164586868856735
GO:0046875	ephrin receptor binding	10/3556	28/18639	0.357142857142857	1.87198698376989	0.0289295111706003	0.172132672937105
GO:0141052	histone H3 demethylase activity	10/3556	28/18639	0.357142857142857	1.87198698376989	0.0289295111706003	0.172132672937105
GO:0019209	kinase activator activity	38/3556	148/18639	0.256756756756757	1.34580685860213	0.0290175665004271	0.172132672937105
GO:0043539	protein serine/threonine kinase activator activity	21/3556	73/18639	0.287671232876712	1.50784704994068	0.0292114987337564	0.172132672937105
GO:0016853	isomerase activity	45/3556	180/18639	0.25	1.31039088863892	0.0293203702271693	0.172132672937105
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	7/3556	17/18639	0.411764705882353	2.15829087540528	0.0296558163112615	0.172132672937105
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	7/3556	17/18639	0.411764705882353	2.15829087540528	0.0296558163112615	0.172132672937105
GO:0019198	transmembrane receptor protein phosphatase activity	7/3556	17/18639	0.411764705882353	2.15829087540528	0.0296558163112615	0.172132672937105
GO:0046965	nuclear retinoid X receptor binding	7/3556	17/18639	0.411764705882353	2.15829087540528	0.0296558163112615	0.172132672937105
GO:0016279	protein-lysine N-methyltransferase activity	20/3556	69/18639	0.289855072463768	1.51929378392918	0.0303531569242366	0.17533584980151
GO:0004177	aminopeptidase activity	13/3556	40/18639	0.325	1.7035081552306	0.0304703499280527	0.17533584980151
GO:0008168	methyltransferase activity	50/3556	204/18639	0.245098039215686	1.284696949646	0.0318030632969461	0.182219268246451
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	8/3556	21/18639	0.380952380952381	1.99678611602121	0.0333003892911308	0.189174551930466
GO:0010314	phosphatidylinositol-5-phosphate binding	8/3556	21/18639	0.380952380952381	1.99678611602121	0.0333003892911308	0.189174551930466
GO:0004601	peroxidase activity	17/3556	57/18639	0.298245614035088	1.5632733408324	0.0336962656881532	0.190612350396968
GO:0016779	nucleotidyltransferase activity	35/3556	136/18639	0.257352941176471	1.3489317971283	0.0339028285553722	0.190971629204312
GO:0016278	lysine N-methyltransferase activity	20/3556	70/18639	0.285714285714286	1.49758958701591	0.0351060575438566	0.196146400281284
GO:0005344	oxygen carrier activity	6/3556	14/18639	0.428571428571429	2.24638438052386	0.03548649842131	0.196146400281284
GO:0004709	MAP kinase kinase kinase activity	9/3556	25/18639	0.36	1.88696287964005	0.0355561264929369	0.196146400281284
GO:0042974	nuclear retinoic acid receptor binding	9/3556	25/18639	0.36	1.88696287964005	0.0355561264929369	0.196146400281284
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	9/3556	25/18639	0.36	1.88696287964005	0.0355561264929369	0.196146400281284
GO:0004386	helicase activity	39/3556	155/18639	0.251612903225806	1.31884502340433	0.0366586781454712	0.201396441663391
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	10/3556	29/18639	0.344827586206897	1.80743570846748	0.0368172080151637	0.201438412705916
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	13/3556	41/18639	0.317073170731707	1.66195917583473	0.037057411972345	0.201925081563594
GO:0042805	actinin binding	12/3556	37/18639	0.324324324324324	1.69996655823427	0.0373965306478051	0.202944587052113
GO:0035401	histone H3Y41 kinase activity	30/3556	115/18639	0.260869565217391	1.36736440553626	0.0396885618641457	0.213646089067075
GO:0140801	histone H2AXY142 kinase activity	30/3556	115/18639	0.260869565217391	1.36736440553626	0.0396885618641457	0.213646089067075
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	7/3556	18/18639	0.388888888888889	2.03838582677165	0.0407344552558865	0.216655369588081
GO:0008525	phosphatidylcholine transporter activity	7/3556	18/18639	0.388888888888889	2.03838582677165	0.0407344552558865	0.216655369588081
GO:0030228	lipoprotein particle receptor activity	7/3556	18/18639	0.388888888888889	2.03838582677165	0.0407344552558865	0.216655369588081
GO:0008526	phosphatidylinositol transfer activity	5/3556	11/18639	0.454545454545455	2.3825288884344	0.041939105556556	0.217854886840475
GO:0010854	adenylate cyclase regulator activity	5/3556	11/18639	0.454545454545455	2.3825288884344	0.041939105556556	0.217854886840475
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	5/3556	11/18639	0.454545454545455	2.3825288884344	0.041939105556556	0.217854886840475
GO:0015205	nucleobase transmembrane transporter activity	5/3556	11/18639	0.454545454545455	2.3825288884344	0.041939105556556	0.217854886840475
GO:0032050	clathrin heavy chain binding	5/3556	11/18639	0.454545454545455	2.3825288884344	0.041939105556556	0.217854886840475
GO:0043522	leucine zipper domain binding	5/3556	11/18639	0.454545454545455	2.3825288884344	0.041939105556556	0.217854886840475
GO:0004721	phosphoprotein phosphatase activity	43/3556	175/18639	0.245714285714286	1.28792704483368	0.0421792533017451	0.218253113014844
GO:0140784	metal ion sensor activity	8/3556	22/18639	0.363636363636364	1.90602311074752	0.0438217348238292	0.225876509613174
GO:0004520	DNA endonuclease activity	13/3556	42/18639	0.30952380952381	1.62238871926723	0.0445960367821127	0.228983496554309
GO:0004435	phosphatidylinositol phospholipase C activity	9/3556	26/18639	0.346153846153846	1.81438738426927	0.0454479082372602	0.231690962856525
GO:0042887	amide transmembrane transporter activity	12/3556	38/18639	0.315789473684211	1.65523059617548	0.0454704361561119	0.231690962856525
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	17/3556	59/18639	0.288135593220339	1.51028102419401	0.0459066733879057	0.232676052772149
GO:0015035	protein-disulfide reductase activity	11/3556	34/18639	0.323529411764706	1.69579997353272	0.0460123430201104	0.232676052772149
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	41/3556	167/18639	0.245508982035928	1.28685093255559	0.0468823053051249	0.236180670122044
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	44/3556	181/18639	0.243093922651934	1.27419224530635	0.0471615994454798	0.236694493457577
GO:0047372	monoacylglycerol lipase activity	6/3556	15/18639	0.4	2.09662542182227	0.0498368501797872	0.249184250898936
GO:0004714	transmembrane receptor protein tyrosine kinase activity	17/3556	60/18639	0.283333333333333	1.48510967379078	0.0530656016683708	0.262629076240198
GO:0008375	acetylglucosaminyltransferase activity	13/3556	43/18639	0.302325581395349	1.58465874905172	0.053139406198725	0.262629076240198
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	7/3556	19/18639	0.368421052631579	1.93110236220472	0.0541851759078428	0.262629076240198
GO:0005229	intracellularly calcium-gated chloride channel activity	7/3556	19/18639	0.368421052631579	1.93110236220472	0.0541851759078428	0.262629076240198
GO:0042800	histone H3K4 methyltransferase activity	7/3556	19/18639	0.368421052631579	1.93110236220472	0.0541851759078428	0.262629076240198
GO:0046527	glucosyltransferase activity	7/3556	19/18639	0.368421052631579	1.93110236220472	0.0541851759078428	0.262629076240198
GO:0046624	sphingolipid transporter activity	7/3556	19/18639	0.368421052631579	1.93110236220472	0.0541851759078428	0.262629076240198
GO:0141147	intracellularly calcium-gated channel activity	7/3556	19/18639	0.368421052631579	1.93110236220472	0.0541851759078428	0.262629076240198
GO:0015291	secondary active transmembrane transporter activity	66/3556	287/18639	0.229965156794425	1.20537698467134	0.0542963483462882	0.262629076240198
GO:0061631	ubiquitin conjugating enzyme activity	11/3556	35/18639	0.314285714285714	1.6473485457175	0.0559294894630601	0.269450687977178
GO:0003887	DNA-directed DNA polymerase activity	8/3556	23/18639	0.347826086956522	1.82315254071502	0.0563121662514101	0.269450687977178
GO:0099186	structural constituent of postsynapse	8/3556	23/18639	0.347826086956522	1.82315254071502	0.0563121662514101	0.269450687977178
GO:0008327	methyl-CpG binding	10/3556	31/18639	0.32258064516129	1.69082695308248	0.0567804921147322	0.27072127490417
GO:0003995	acyl-CoA dehydrogenase activity	5/3556	12/18639	0.416666666666667	2.1839848143982	0.0608789795861891	0.285588069902923
GO:0035251	UDP-glucosyltransferase activity	5/3556	12/18639	0.416666666666667	2.1839848143982	0.0608789795861891	0.285588069902923
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	5/3556	12/18639	0.416666666666667	2.1839848143982	0.0608789795861891	0.285588069902923
GO:0070410	co-SMAD binding	5/3556	12/18639	0.416666666666667	2.1839848143982	0.0608789795861891	0.285588069902923
GO:0015026	coreceptor activity	17/3556	61/18639	0.278688524590164	1.4607636135647	0.0609682396421971	0.285588069902923
GO:0015932	nucleobase-containing compound transmembrane transporter activity	16/3556	57/18639	0.280701754385965	1.47131608548931	0.0639589497199062	0.298549642923339
GO:0015036	disulfide oxidoreductase activity	12/3556	40/18639	0.3	1.5724690663667	0.065039415097859	0.301484788734867
GO:0032451	demethylase activity	12/3556	40/18639	0.3	1.5724690663667	0.065039415097859	0.301484788734867
GO:0008238	exopeptidase activity	26/3556	102/18639	0.254901960784314	1.33608482763184	0.0671061148388773	0.305412151483755
GO:0000993	RNA polymerase II complex binding	11/3556	36/18639	0.305555555555556	1.60158886389201	0.0671678915055313	0.305412151483755
GO:0005484	SNAP receptor activity	11/3556	36/18639	0.305555555555556	1.60158886389201	0.0671678915055313	0.305412151483755
GO:0030275	LRR domain binding	6/3556	16/18639	0.375	1.96558633295838	0.0672593052705798	0.305412151483755
GO:0031435	mitogen-activated protein kinase kinase kinase binding	6/3556	16/18639	0.375	1.96558633295838	0.0672593052705798	0.305412151483755
GO:0070411	I-SMAD binding	6/3556	16/18639	0.375	1.96558633295838	0.0672593052705798	0.305412151483755
GO:0051219	phosphoprotein binding	24/3556	93/18639	0.258064516129032	1.35266156246598	0.0676304591259913	0.306056484519317
GO:0016887	ATP hydrolysis activity	92/3556	417/18639	0.220623501199041	1.15641210316336	0.067962909890054	0.306521907781156
GO:0061775	cohesin loader activity	37/3556	153/18639	0.241830065359477	1.26756765698405	0.0684801755342383	0.307814930431677
GO:0071813	lipoprotein particle binding	10/3556	32/18639	0.3125	1.63798861079865	0.0689907407020937	0.308035581395636
GO:0071814	protein-lipid complex binding	10/3556	32/18639	0.3125	1.63798861079865	0.0689907407020937	0.308035581395636
GO:0005326	neurotransmitter transmembrane transporter activity	7/3556	20/18639	0.35	1.83454724409449	0.0700969350087562	0.308072520878761
GO:0010851	cyclase regulator activity	7/3556	20/18639	0.35	1.83454724409449	0.0700969350087562	0.308072520878761
GO:0016763	pentosyltransferase activity	14/3556	49/18639	0.285714285714286	1.49758958701591	0.0702025691493477	0.308072520878761
GO:0140658	ATP-dependent chromatin remodeler activity	38/3556	158/18639	0.240506329113924	1.26062920932352	0.0702687469466318	0.308072520878761
GO:0022804	active transmembrane transporter activity	100/3556	457/18639	0.218818380743982	1.14695044957455	0.0706334363489389	0.308072520878761
GO:0008094	ATP-dependent activity, acting on DNA	49/3556	210/18639	0.233333333333333	1.22303149606299	0.0706700799825408	0.308072520878761
GO:0015295	solute:proton symporter activity	8/3556	24/18639	0.333333333333333	1.74718785151856	0.0708451415054529	0.308072520878761
GO:0050431	transforming growth factor beta binding	8/3556	24/18639	0.333333333333333	1.74718785151856	0.0708451415054529	0.308072520878761
GO:0003727	single-stranded RNA binding	23/3556	89/18639	0.258426966292135	1.35456136803124	0.0714807502591339	0.309827277908908
GO:0061980	regulatory RNA binding	16/3556	58/18639	0.275862068965517	1.44594856677398	0.0732913050090621	0.31664690028187
GO:0140104	molecular carrier activity	57/3556	249/18639	0.228915662650602	1.19987599441636	0.0743468583163328	0.320062994217101
GO:0140097	catalytic activity, acting on DNA	75/3556	336/18639	0.223214285714286	1.16999186485618	0.0745614915367178	0.320062994217101
GO:0001217	DNA-binding transcription repressor activity	63/3556	278/18639	0.226618705035971	1.18783634509715	0.0749512584300471	0.320704903859336
GO:0044389	ubiquitin-like protein ligase binding	72/3556	322/18639	0.22360248447205	1.1720266333168	0.0768415059906613	0.326783998959358
GO:0003925	G protein activity	15/3556	54/18639	0.277777777777778	1.45598987626547	0.0771063368331068	0.326783998959358
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	15/3556	54/18639	0.277777777777778	1.45598987626547	0.0771063368331068	0.326783998959358
GO:0002020	protease binding	33/3556	136/18639	0.242647058823529	1.27184998014954	0.0784853719192914	0.331575859215994
GO:0140597	protein carrier chaperone	44/3556	188/18639	0.234042553191489	1.22674891702367	0.0797020587745866	0.335653780643764
GO:0015605	organophosphate ester transmembrane transporter activity	14/3556	50/18639	0.28	1.46763779527559	0.0810785353346891	0.340376870037138
GO:0140416	transcription regulator inhibitor activity	10/3556	33/18639	0.303030303030303	1.5883525922896	0.0827414182806019	0.341290716729582
GO:0031593	polyubiquitin modification-dependent protein binding	16/3556	59/18639	0.271186440677966	1.4214409639473	0.0834809353797248	0.341290716729582
GO:0070063	RNA polymerase binding	16/3556	59/18639	0.271186440677966	1.4214409639473	0.0834809353797248	0.341290716729582
GO:0004535	poly(A)-specific ribonuclease activity	5/3556	13/18639	0.384615384615385	2.01598598252142	0.0838728224651351	0.341290716729582
GO:0005172	vascular endothelial growth factor receptor binding	5/3556	13/18639	0.384615384615385	2.01598598252142	0.0838728224651351	0.341290716729582
GO:0005338	nucleotide-sugar transmembrane transporter activity	5/3556	13/18639	0.384615384615385	2.01598598252142	0.0838728224651351	0.341290716729582
GO:0070123	transforming growth factor beta receptor activity, type III	5/3556	13/18639	0.384615384615385	2.01598598252142	0.0838728224651351	0.341290716729582
GO:0140410	monoatomic cation:bicarbonate symporter activity	5/3556	13/18639	0.384615384615385	2.01598598252142	0.0838728224651351	0.341290716729582
GO:0050660	flavin adenine dinucleotide binding	22/3556	86/18639	0.255813953488372	1.34086509535145	0.0839891897932759	0.341290716729582
GO:0000510	H3-H4 histone complex chaperone activity	36/3556	151/18639	0.23841059602649	1.24964429115235	0.0846196458707803	0.341290716729582
GO:0140584	chromatin extrusion motor activity	36/3556	151/18639	0.23841059602649	1.24964429115235	0.0846196458707803	0.341290716729582
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	36/3556	151/18639	0.23841059602649	1.24964429115235	0.0846196458707803	0.341290716729582
GO:0140849	ATP-dependent H2AZ histone chaperone activity	36/3556	151/18639	0.23841059602649	1.24964429115235	0.0846196458707803	0.341290716729582
GO:0016417	S-acyltransferase activity	9/3556	29/18639	0.310344827586207	1.62669213762073	0.085390476872348	0.342331191064819
GO:0051861	glycolipid binding	9/3556	29/18639	0.310344827586207	1.62669213762073	0.085390476872348	0.342331191064819
GO:0000030	mannosyltransferase activity	8/3556	25/18639	0.32	1.67730033745782	0.0874517368054605	0.342437978270158
GO:0017056	structural constituent of nuclear pore	8/3556	25/18639	0.32	1.67730033745782	0.0874517368054605	0.342437978270158
GO:0019706	protein-cysteine S-palmitoyltransferase activity	8/3556	25/18639	0.32	1.67730033745782	0.0874517368054605	0.342437978270158
GO:0019707	protein-cysteine S-acyltransferase activity	8/3556	25/18639	0.32	1.67730033745782	0.0874517368054605	0.342437978270158
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	6/3556	17/18639	0.352941176470588	1.84996360749024	0.0877702992483898	0.342437978270158
GO:0017110	nucleoside diphosphate phosphatase activity	6/3556	17/18639	0.352941176470588	1.84996360749024	0.0877702992483898	0.342437978270158
GO:0030169	low-density lipoprotein particle binding	6/3556	17/18639	0.352941176470588	1.84996360749024	0.0877702992483898	0.342437978270158
GO:0038191	neuropilin binding	6/3556	17/18639	0.352941176470588	1.84996360749024	0.0877702992483898	0.342437978270158
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	7/3556	21/18639	0.333333333333333	1.74718785151856	0.0884952078675689	0.342437978270158
GO:0051010	microtubule plus-end binding	7/3556	21/18639	0.333333333333333	1.74718785151856	0.0884952078675689	0.342437978270158
GO:0061891	calcium ion sensor activity	7/3556	21/18639	0.333333333333333	1.74718785151856	0.0884952078675689	0.342437978270158
GO:0140312	cargo adaptor activity	7/3556	21/18639	0.333333333333333	1.74718785151856	0.0884952078675689	0.342437978270158
GO:0004536	DNA nuclease activity	17/3556	64/18639	0.265625	1.39229031917885	0.0893676879519329	0.344049237623998
GO:0043175	RNA polymerase core enzyme binding	12/3556	42/18639	0.285714285714286	1.49758958701591	0.0894270303037658	0.344049237623998
GO:0015616	DNA translocase activity	36/3556	152/18639	0.236842105263158	1.24142294713161	0.0912935534940085	0.34921746107307
GO:0140674	ATP-dependent histone chaperone activity	36/3556	152/18639	0.236842105263158	1.24142294713161	0.0912935534940085	0.34921746107307
GO:0004222	metalloendopeptidase activity	27/3556	110/18639	0.245454545454545	1.28656559975458	0.0925151682860214	0.35287928474811
GO:0008081	phosphoric diester hydrolase activity	22/3556	87/18639	0.252873563218391	1.32545285287615	0.0930002842573418	0.353719029867667
GO:0042162	telomeric DNA binding	11/3556	38/18639	0.289473684210526	1.51729471316085	0.0937347021443678	0.355499509553213
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	60/3556	268/18639	0.223880597014925	1.1734843778856	0.0966745834883987	0.365610676932046
GO:0008376	acetylgalactosaminyltransferase activity	10/3556	34/18639	0.294117647058824	1.5416363395752	0.0980451996391402	0.367875245667869
GO:0090482	vitamin transmembrane transporter activity	10/3556	34/18639	0.294117647058824	1.5416363395752	0.0980451996391402	0.367875245667869
GO:0001784	phosphotyrosine residue binding	13/3556	47/18639	0.276595744680851	1.44979417466434	0.0981000655114318	0.367875245667869
GO:0031491	nucleosome binding	19/3556	74/18639	0.256756756756757	1.34580685860213	0.0998403372051637	0.373352521481494
GO:0001968	fibronectin binding	9/3556	30/18639	0.3	1.5724690663667	0.102239923762555	0.378089468761804
GO:0008187	poly-pyrimidine tract binding	9/3556	30/18639	0.3	1.5724690663667	0.102239923762555	0.378089468761804
GO:0031210	phosphatidylcholine binding	9/3556	30/18639	0.3	1.5724690663667	0.102239923762555	0.378089468761804
GO:0098918	structural constituent of synapse	9/3556	30/18639	0.3	1.5724690663667	0.102239923762555	0.378089468761804
GO:0004197	cysteine-type endopeptidase activity	22/3556	88/18639	0.25	1.31039088863892	0.102615836325188	0.37843133009427
GO:0004382	GDP phosphatase activity	4/3556	10/18639	0.4	2.09662542182227	0.105147638878834	0.380412189439685
GO:0005131	growth hormone receptor binding	4/3556	10/18639	0.4	2.09662542182227	0.105147638878834	0.380412189439685
GO:0005522	profilin binding	4/3556	10/18639	0.4	2.09662542182227	0.105147638878834	0.380412189439685
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	4/3556	10/18639	0.4	2.09662542182227	0.105147638878834	0.380412189439685
GO:0019911	structural constituent of myelin sheath	4/3556	10/18639	0.4	2.09662542182227	0.105147638878834	0.380412189439685
GO:0045322	unmethylated CpG binding	4/3556	10/18639	0.4	2.09662542182227	0.105147638878834	0.380412189439685
GO:0051880	G-quadruplex DNA binding	4/3556	10/18639	0.4	2.09662542182227	0.105147638878834	0.380412189439685
GO:0030159	signaling receptor complex adaptor activity	14/3556	52/18639	0.269230769230769	1.41119018776499	0.105899570998646	0.380834247990381
GO:0050681	nuclear androgen receptor binding	8/3556	26/18639	0.307692307692308	1.61278878601713	0.106120105057994	0.380834247990381
GO:0120014	phospholipid transfer activity	8/3556	26/18639	0.307692307692308	1.61278878601713	0.106120105057994	0.380834247990381
GO:0019888	protein phosphatase regulator activity	26/3556	107/18639	0.242990654205607	1.27365095718175	0.106899502614994	0.38260277745581
GO:0140713	histone chaperone activity	38/3556	164/18639	0.231707317073171	1.21450862849461	0.109213295949337	0.386900456670825
GO:0008170	N-methyltransferase activity	24/3556	98/18639	0.244897959183673	1.28364821744221	0.109944555350163	0.386900456670825
GO:0004705	JUN kinase activity	5/3556	14/18639	0.357142857142857	1.87198698376989	0.110754113600594	0.386900456670825
GO:0005545	1-phosphatidylinositol binding	5/3556	14/18639	0.357142857142857	1.87198698376989	0.110754113600594	0.386900456670825
GO:0008559	ABC-type xenobiotic transporter activity	5/3556	14/18639	0.357142857142857	1.87198698376989	0.110754113600594	0.386900456670825
GO:0015926	glucosidase activity	5/3556	14/18639	0.357142857142857	1.87198698376989	0.110754113600594	0.386900456670825
GO:0070742	C2H2 zinc finger domain binding	5/3556	14/18639	0.357142857142857	1.87198698376989	0.110754113600594	0.386900456670825
GO:0004706	JUN kinase kinase kinase activity	6/3556	18/18639	0.333333333333333	1.74718785151856	0.111288221244642	0.386900456670825
GO:0034185	apolipoprotein binding	6/3556	18/18639	0.333333333333333	1.74718785151856	0.111288221244642	0.386900456670825
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	6/3556	18/18639	0.333333333333333	1.74718785151856	0.111288221244642	0.386900456670825
GO:1901611	phosphatidylglycerol binding	6/3556	18/18639	0.333333333333333	1.74718785151856	0.111288221244642	0.386900456670825
GO:0019208	phosphatase regulator activity	28/3556	117/18639	0.239316239316239	1.25439127801333	0.112647246175681	0.390607983492296
GO:0140789	histone phosphatase activity	32/3556	136/18639	0.235294117647059	1.23330907166016	0.1136020592964	0.392898313887809
GO:0043015	gamma-tubulin binding	10/3556	35/18639	0.285714285714286	1.49758958701591	0.114891483709572	0.395797851765198
GO:0003689	DNA clamp loader activity	37/3556	160/18639	0.23125	1.212111571991	0.115169503294883	0.395797851765198
GO:0008237	metallopeptidase activity	42/3556	184/18639	0.228260869565217	1.19644385484423	0.115329860926338	0.395797851765198
GO:0043014	alpha-tubulin binding	12/3556	44/18639	0.272727272727273	1.42951733306064	0.118752018937303	0.406497295593074
GO:0016860	intramolecular oxidoreductase activity	14/3556	53/18639	0.264150943396226	1.38456395780716	0.119848042690327	0.409199838853164
GO:0016411	acylglycerol O-acyltransferase activity	9/3556	31/18639	0.290322580645161	1.52174425777423	0.120836963982119	0.411523844173798
GO:0008173	RNA methyltransferase activity	17/3556	67/18639	0.253731343283582	1.32994896160368	0.125058370606155	0.423738387713749
GO:0050840	extracellular matrix binding	17/3556	67/18639	0.253731343283582	1.32994896160368	0.125058370606155	0.423738387713749
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	11/3556	40/18639	0.275	1.44142997750281	0.125787893416785	0.425131234712426
GO:0008408	3'-5' exonuclease activity	15/3556	58/18639	0.258620689655172	1.35557678135061	0.126760246527641	0.426381825302355
GO:0008266	poly(U) RNA binding	8/3556	27/18639	0.296296296296296	1.5530558680165	0.126796692618004	0.426381825302355
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	21/3556	86/18639	0.244186046511628	1.27991668192639	0.131282778362388	0.440358063099969
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	7/3556	23/18639	0.304347826086957	1.59525847312564	0.132543743408147	0.443473427192673
GO:1901682	sulfur compound transmembrane transporter activity	16/3556	63/18639	0.253968253968254	1.33119074401414	0.132972910778609	0.443797089723606
GO:0140303	intramembrane lipid transporter activity	12/3556	45/18639	0.266666666666667	1.39775028121485	0.135240442884692	0.449814128072003
GO:0015245	fatty acid transmembrane transporter activity	6/3556	19/18639	0.315789473684211	1.65523059617548	0.137643472938549	0.449814128072003
GO:0043395	heparan sulfate proteoglycan binding	6/3556	19/18639	0.315789473684211	1.65523059617548	0.137643472938549	0.449814128072003
GO:0140036	ubiquitin-modified protein reader activity	6/3556	19/18639	0.315789473684211	1.65523059617548	0.137643472938549	0.449814128072003
GO:0004896	cytokine receptor activity	23/3556	96/18639	0.239583333333333	1.25579126827897	0.138638291865386	0.449814128072003
GO:0051059	NF-kappaB binding	9/3556	32/18639	0.28125	1.47418974971879	0.141124616569955	0.449814128072003
GO:0070717	poly-purine tract binding	9/3556	32/18639	0.28125	1.47418974971879	0.141124616569955	0.449814128072003
GO:0005041	low-density lipoprotein particle receptor activity	5/3556	15/18639	0.333333333333333	1.74718785151856	0.141212745310997	0.449814128072003
GO:0005402	carbohydrate:monoatomic cation symporter activity	5/3556	15/18639	0.333333333333333	1.74718785151856	0.141212745310997	0.449814128072003
GO:0042809	nuclear vitamin D receptor binding	5/3556	15/18639	0.333333333333333	1.74718785151856	0.141212745310997	0.449814128072003
GO:0050780	dopamine receptor binding	5/3556	15/18639	0.333333333333333	1.74718785151856	0.141212745310997	0.449814128072003
GO:0016176	superoxide-generating NADPH oxidase activator activity	4/3556	11/18639	0.363636363636364	1.90602311074752	0.141266800777279	0.449814128072003
GO:0032794	GTPase activating protein binding	4/3556	11/18639	0.363636363636364	1.90602311074752	0.141266800777279	0.449814128072003
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	4/3556	11/18639	0.363636363636364	1.90602311074752	0.141266800777279	0.449814128072003
GO:0034713	type I transforming growth factor beta receptor binding	4/3556	11/18639	0.363636363636364	1.90602311074752	0.141266800777279	0.449814128072003
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	4/3556	11/18639	0.363636363636364	1.90602311074752	0.141266800777279	0.449814128072003
GO:0047676	arachidonate-CoA ligase activity	4/3556	11/18639	0.363636363636364	1.90602311074752	0.141266800777279	0.449814128072003
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	4/3556	11/18639	0.363636363636364	1.90602311074752	0.141266800777279	0.449814128072003
GO:0140537	transcription regulator activator activity	4/3556	11/18639	0.363636363636364	1.90602311074752	0.141266800777279	0.449814128072003
GO:0001786	phosphatidylserine binding	15/3556	59/18639	0.254237288135593	1.3326009037006	0.141514557146248	0.449814128072003
GO:0005007	fibroblast growth factor receptor activity	13/3556	50/18639	0.26	1.36280652418448	0.143497260949273	0.452819374694852
GO:0005017	platelet-derived growth factor receptor activity	13/3556	50/18639	0.26	1.36280652418448	0.143497260949273	0.452819374694852
GO:0005019	platelet-derived growth factor beta-receptor activity	13/3556	50/18639	0.26	1.36280652418448	0.143497260949273	0.452819374694852
GO:0061650	ubiquitin-like protein conjugating enzyme activity	11/3556	41/18639	0.268292682926829	1.40627314878323	0.143816790165256	0.452819374694852
GO:0005319	lipid transporter activity	40/3556	178/18639	0.224719101123595	1.17787945046195	0.144501135275526	0.45390356610077
GO:0008017	microtubule binding	60/3556	276/18639	0.217391304347826	1.13947033794689	0.145712944261417	0.456635635185427
GO:0051393	alpha-actinin binding	8/3556	28/18639	0.285714285714286	1.49758958701591	0.149388964015779	0.467059173210924
GO:0043394	proteoglycan binding	10/3556	37/18639	0.27027027027027	1.41663879852856	0.153055320453441	0.477403861694729
GO:0001098	basal transcription machinery binding	15/3556	60/18639	0.25	1.31039088863892	0.157172390618562	0.4868332748858
GO:0001099	basal RNA polymerase II transcription machinery binding	15/3556	60/18639	0.25	1.31039088863892	0.157172390618562	0.4868332748858
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	15/3556	60/18639	0.25	1.31039088863892	0.157172390618562	0.4868332748858
GO:0030215	semaphorin receptor binding	7/3556	24/18639	0.291666666666667	1.52878937007874	0.157949050073963	0.488106439464676
GO:0005010	insulin-like growth factor receptor activity	13/3556	51/18639	0.254901960784314	1.33608482763184	0.160781078901545	0.493431586973706
GO:0005021	vascular endothelial growth factor receptor activity	13/3556	51/18639	0.254901960784314	1.33608482763184	0.160781078901545	0.493431586973706
GO:0016597	amino acid binding	13/3556	51/18639	0.254901960784314	1.33608482763184	0.160781078901545	0.493431586973706
GO:0042626	ATPase-coupled transmembrane transporter activity	23/3556	98/18639	0.23469387755102	1.23016287504878	0.162970485212559	0.497169795592511
GO:0071889	14-3-3 protein binding	9/3556	33/18639	0.272727272727273	1.42951733306064	0.163018315928463	0.497169795592511
GO:0031492	nucleosomal DNA binding	11/3556	42/18639	0.261904761904762	1.37279045476458	0.163116382374172	0.497169795592511
GO:0001614	purinergic nucleotide receptor activity	6/3556	20/18639	0.3	1.5724690663667	0.166591989194174	0.503529162782921
GO:0016502	nucleotide receptor activity	6/3556	20/18639	0.3	1.5724690663667	0.166591989194174	0.503529162782921
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	6/3556	20/18639	0.3	1.5724690663667	0.166591989194174	0.503529162782921
GO:0008514	organic anion transmembrane transporter activity	58/3556	269/18639	0.215613382899628	1.13015124968115	0.166711528052473	0.503529162782921
GO:0030170	pyridoxal phosphate binding	14/3556	56/18639	0.25	1.31039088863892	0.167659161373283	0.505248262829194
GO:0043236	laminin binding	8/3556	29/18639	0.275862068965517	1.44594856677398	0.173769340070419	0.517628311287863
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	10/3556	38/18639	0.263157894736842	1.37935883014623	0.174241255563825	0.517628311287863
GO:0005324	long-chain fatty acid transmembrane transporter activity	5/3556	16/18639	0.3125	1.63798861079865	0.174827945329368	0.517628311287863
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	5/3556	16/18639	0.3125	1.63798861079865	0.174827945329368	0.517628311287863
GO:0034450	ubiquitin-ubiquitin ligase activity	5/3556	16/18639	0.3125	1.63798861079865	0.174827945329368	0.517628311287863
GO:0031490	chromatin DNA binding	29/3556	128/18639	0.2265625	1.18754174282902	0.177505648889903	0.517628311287863
GO:0005080	protein kinase C binding	13/3556	52/18639	0.25	1.31039088863892	0.179074914869178	0.517628311287863
GO:0005025	transforming growth factor beta receptor activity, type I	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0005026	transforming growth factor beta receptor activity, type II	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0005165	neurotrophin receptor binding	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0008179	adenylate cyclase binding	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0008504	monoamine transmembrane transporter activity	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0008603	cAMP-dependent protein kinase regulator activity	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0010853	cyclase activator activity	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0016361	activin receptor activity, type I	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0016362	activin receptor activity, type II	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0017002	activin receptor activity	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0017166	vinculin binding	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0035014	phosphatidylinositol 3-kinase regulator activity	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0035259	nuclear glucocorticoid receptor binding	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0045295	gamma-catenin binding	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	4/3556	12/18639	0.333333333333333	1.74718785151856	0.181460711372824	0.517628311287863
GO:0008234	cysteine-type peptidase activity	41/3556	187/18639	0.219251336898396	1.14921981677424	0.182447420020734	0.519333274472666
GO:0005537	D-mannose binding	7/3556	25/18639	0.28	1.46763779527559	0.185364671900602	0.521288786246098
GO:0015296	monoatomic anion:monoatomic cation symporter activity	7/3556	25/18639	0.28	1.46763779527559	0.185364671900602	0.521288786246098
GO:0019211	phosphatase activator activity	7/3556	25/18639	0.28	1.46763779527559	0.185364671900602	0.521288786246098
GO:0120020	cholesterol transfer activity	7/3556	25/18639	0.28	1.46763779527559	0.185364671900602	0.521288786246098
GO:0016504	peptidase activator activity	14/3556	57/18639	0.245614035087719	1.28740157480315	0.185477283495803	0.521288786246098
GO:0070279	vitamin B6 binding	14/3556	57/18639	0.245614035087719	1.28740157480315	0.185477283495803	0.521288786246098
GO:0031625	ubiquitin protein ligase binding	64/3556	302/18639	0.211920529801325	1.11079492546875	0.191476092827336	0.536096088922515
GO:0036121	double-stranded DNA helicase activity	12/3556	48/18639	0.25	1.31039088863892	0.191548939637483	0.536096088922515
GO:0140767	enzyme-substrate adaptor activity	31/3556	139/18639	0.223021582733813	1.16898179993688	0.192546093903722	0.537759488203911
GO:0016209	antioxidant activity	20/3556	86/18639	0.232558139534884	1.21896826850132	0.195194051911294	0.544016825264254
GO:0005123	death receptor binding	6/3556	21/18639	0.285714285714286	1.49758958701591	0.197830701724816	0.544777922874386
GO:0019200	carbohydrate kinase activity	6/3556	21/18639	0.285714285714286	1.49758958701591	0.197830701724816	0.544777922874386
GO:0036122	BMP binding	6/3556	21/18639	0.285714285714286	1.49758958701591	0.197830701724816	0.544777922874386
GO:0072542	protein phosphatase activator activity	6/3556	21/18639	0.285714285714286	1.49758958701591	0.197830701724816	0.544777922874386
GO:0005003	ephrin receptor activity	13/3556	53/18639	0.245283018867925	1.28566653224951	0.198323648327304	0.544777922874386
GO:0005005	transmembrane-ephrin receptor activity	13/3556	53/18639	0.245283018867925	1.28566653224951	0.198323648327304	0.544777922874386
GO:0005544	calcium-dependent phospholipid binding	13/3556	53/18639	0.245283018867925	1.28566653224951	0.198323648327304	0.544777922874386
GO:0001965	G-protein alpha-subunit binding	8/3556	30/18639	0.266666666666667	1.39775028121485	0.199780036909642	0.546529404250763
GO:0035925	mRNA 3'-UTR AU-rich region binding	8/3556	30/18639	0.266666666666667	1.39775028121485	0.199780036909642	0.546529404250763
GO:0000175	3'-5'-RNA exonuclease activity	9/3556	35/18639	0.257142857142857	1.34783062831432	0.211164575744442	0.567099148211269
GO:0034061	DNA polymerase activity	9/3556	35/18639	0.257142857142857	1.34783062831432	0.211164575744442	0.567099148211269
GO:0005004	GPI-linked ephrin receptor activity	12/3556	49/18639	0.244897959183673	1.28364821744221	0.212396684723322	0.567099148211269
GO:0005008	hepatocyte growth factor receptor activity	12/3556	49/18639	0.244897959183673	1.28364821744221	0.212396684723322	0.567099148211269
GO:0005009	insulin receptor activity	12/3556	49/18639	0.244897959183673	1.28364821744221	0.212396684723322	0.567099148211269
GO:0005011	macrophage colony-stimulating factor receptor activity	12/3556	49/18639	0.244897959183673	1.28364821744221	0.212396684723322	0.567099148211269
GO:0005018	platelet-derived growth factor alpha-receptor activity	12/3556	49/18639	0.244897959183673	1.28364821744221	0.212396684723322	0.567099148211269
GO:0005020	stem cell factor receptor activity	12/3556	49/18639	0.244897959183673	1.28364821744221	0.212396684723322	0.567099148211269
GO:0008288	boss receptor activity	12/3556	49/18639	0.244897959183673	1.28364821744221	0.212396684723322	0.567099148211269
GO:0036332	placental growth factor receptor activity	12/3556	49/18639	0.244897959183673	1.28364821744221	0.212396684723322	0.567099148211269
GO:0038062	protein tyrosine kinase collagen receptor activity	12/3556	49/18639	0.244897959183673	1.28364821744221	0.212396684723322	0.567099148211269
GO:0060175	brain-derived neurotrophic factor receptor activity	12/3556	49/18639	0.244897959183673	1.28364821744221	0.212396684723322	0.567099148211269
GO:0043178	alcohol binding	21/3556	92/18639	0.228260869565217	1.19644385484423	0.213369159360794	0.568328673757618
GO:0001637	G protein-coupled chemoattractant receptor activity	7/3556	26/18639	0.269230769230769	1.41119018776499	0.214560038632089	0.568328673757618
GO:0004950	chemokine receptor activity	7/3556	26/18639	0.269230769230769	1.41119018776499	0.214560038632089	0.568328673757618
GO:0070006	metalloaminopeptidase activity	7/3556	26/18639	0.269230769230769	1.41119018776499	0.214560038632089	0.568328673757618
GO:0015485	cholesterol binding	13/3556	54/18639	0.240740740740741	1.2618578927634	0.21846287056219	0.576379312649257
GO:0051287	NAD binding	13/3556	54/18639	0.240740740740741	1.2618578927634	0.21846287056219	0.576379312649257
GO:0004532	RNA exonuclease activity	10/3556	40/18639	0.25	1.31039088863892	0.220350626249501	0.577259573869373
GO:0015144	carbohydrate transmembrane transporter activity	10/3556	40/18639	0.25	1.31039088863892	0.220350626249501	0.577259573869373
GO:0005178	integrin binding	35/3556	161/18639	0.217391304347826	1.13947033794689	0.220389845357884	0.577259573869373
GO:0045309	protein phosphorylated amino acid binding	14/3556	59/18639	0.23728813559322	1.24376084345389	0.223649663277129	0.577259573869373
GO:0030165	PDZ domain binding	19/3556	83/18639	0.228915662650602	1.19987599441636	0.223951727136626	0.577259573869373
GO:0017154	semaphorin receptor activity	4/3556	13/18639	0.307692307692308	1.61278878601713	0.224833106442908	0.577259573869373
GO:0046975	histone H3K36 methyltransferase activity	4/3556	13/18639	0.307692307692308	1.61278878601713	0.224833106442908	0.577259573869373
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	4/3556	13/18639	0.307692307692308	1.61278878601713	0.224833106442908	0.577259573869373
GO:0071714	icosanoid transmembrane transporter activity	4/3556	13/18639	0.307692307692308	1.61278878601713	0.224833106442908	0.577259573869373
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	4/3556	13/18639	0.307692307692308	1.61278878601713	0.224833106442908	0.577259573869373
GO:0140666	annealing activity	4/3556	13/18639	0.307692307692308	1.61278878601713	0.224833106442908	0.577259573869373
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	4/3556	13/18639	0.307692307692308	1.61278878601713	0.224833106442908	0.577259573869373
GO:0140852	histone ubiquitin ligase activity	4/3556	13/18639	0.307692307692308	1.61278878601713	0.224833106442908	0.577259573869373
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	27/3556	122/18639	0.221311475409836	1.16001816371314	0.224850171095187	0.577259573869373
GO:0004407	histone deacetylase activity	6/3556	22/18639	0.272727272727273	1.42951733306064	0.23101365413863	0.585205366745865
GO:0008649	rRNA methyltransferase activity	6/3556	22/18639	0.272727272727273	1.42951733306064	0.23101365413863	0.585205366745865
GO:0015377	chloride:monoatomic cation symporter activity	6/3556	22/18639	0.272727272727273	1.42951733306064	0.23101365413863	0.585205366745865
GO:0033558	protein lysine deacetylase activity	6/3556	22/18639	0.272727272727273	1.42951733306064	0.23101365413863	0.585205366745865
GO:0070034	telomerase RNA binding	6/3556	22/18639	0.272727272727273	1.42951733306064	0.23101365413863	0.585205366745865
GO:0140035	ubiquitin-like protein reader activity	6/3556	22/18639	0.272727272727273	1.42951733306064	0.23101365413863	0.585205366745865
GO:0140517	protein-RNA adaptor activity	6/3556	22/18639	0.272727272727273	1.42951733306064	0.23101365413863	0.585205366745865
GO:0008201	heparin binding	37/3556	172/18639	0.215116279069767	1.12754564836372	0.233300282655917	0.589878555578881
GO:0005006	epidermal growth factor receptor activity	12/3556	50/18639	0.24	1.25797525309336	0.234154397494075	0.590030342771427
GO:0031406	carboxylic acid binding	40/3556	187/18639	0.213903743315508	1.1211900651456	0.234402042291245	0.590030342771427
GO:0004843	cysteine-type deubiquitinase activity	24/3556	108/18639	0.222222222222222	1.16479190101237	0.234686226225938	0.590030342771427
GO:0015370	solute:sodium symporter activity	18/3556	79/18639	0.227848101265823	1.19428030356965	0.238292695326695	0.597971331317929
GO:0098632	cell-cell adhesion mediator activity	13/3556	55/18639	0.236363636363636	1.23891502198589	0.239419922160749	0.599672788151218
GO:0004527	exonuclease activity	19/3556	84/18639	0.226190476190476	1.18559175638759	0.240870142847589	0.602175357118972
GO:0042169	SH2 domain binding	10/3556	41/18639	0.24390243902439	1.27843013525748	0.245038960470225	0.60863396839948
GO:0140318	protein transporter activity	10/3556	41/18639	0.24390243902439	1.27843013525748	0.245038960470225	0.60863396839948
GO:0004683	calcium/calmodulin-dependent protein kinase activity	7/3556	27/18639	0.259259259259259	1.35892388451444	0.245277209737019	0.60863396839948
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	7/3556	27/18639	0.259259259259259	1.35892388451444	0.245277209737019	0.60863396839948
GO:0120013	lipid transfer activity	15/3556	65/18639	0.230769230769231	1.20959158951285	0.247688549439585	0.612264045650809
GO:0003746	translation elongation factor activity	5/3556	18/18639	0.277777777777778	1.45598987626547	0.249491865793288	0.612264045650809
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	5/3556	18/18639	0.277777777777778	1.45598987626547	0.249491865793288	0.612264045650809
GO:0017075	syntaxin-1 binding	5/3556	18/18639	0.277777777777778	1.45598987626547	0.249491865793288	0.612264045650809
GO:0017128	phospholipid scramblase activity	5/3556	18/18639	0.277777777777778	1.45598987626547	0.249491865793288	0.612264045650809
GO:0035615	clathrin adaptor activity	5/3556	18/18639	0.277777777777778	1.45598987626547	0.249491865793288	0.612264045650809
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	11/3556	46/18639	0.239130434782609	1.25341737174158	0.251454150429433	0.615574929707176
GO:0015631	tubulin binding	79/3556	385/18639	0.205194805194805	1.07554161249324	0.251763229677991	0.615574929707176
GO:0003725	double-stranded RNA binding	17/3556	75/18639	0.226666666666667	1.18808773903262	0.253765661370195	0.619336668974791
GO:0022884	macromolecule transmembrane transporter activity	8/3556	32/18639	0.25	1.31039088863892	0.25594312388781	0.622024722852683
GO:0005030	neurotrophin receptor activity	12/3556	51/18639	0.235294117647059	1.23330907166016	0.256730803214853	0.622024722852683
GO:0005048	signal sequence binding	12/3556	51/18639	0.235294117647059	1.23330907166016	0.256730803214853	0.622024722852683
GO:0030544	Hsp70 protein binding	12/3556	51/18639	0.235294117647059	1.23330907166016	0.256730803214853	0.622024722852683
GO:0043177	organic acid binding	40/3556	189/18639	0.211640211640212	1.10932562001178	0.257376533638645	0.622459551463029
GO:0170055	lipid transmembrane transporter activity	13/3556	56/18639	0.232142857142857	1.21679153945043	0.261115035887192	0.630359083018808
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	6/3556	23/18639	0.260869565217391	1.36736440553626	0.2657677402788	0.638346444836039
GO:0140102	catalytic activity, acting on a rRNA	6/3556	23/18639	0.260869565217391	1.36736440553626	0.2657677402788	0.638346444836039
GO:0101005	deubiquitinase activity	25/3556	115/18639	0.217391304347826	1.13947033794689	0.266148416338192	0.638346444836039
GO:0008235	metalloexopeptidase activity	15/3556	66/18639	0.227272727272727	1.1912644442172	0.267878210586371	0.638346444836039
GO:0004065	arylsulfatase activity	4/3556	14/18639	0.285714285714286	1.49758958701591	0.270464703579833	0.638346444836039
GO:0005161	platelet-derived growth factor receptor binding	4/3556	14/18639	0.285714285714286	1.49758958701591	0.270464703579833	0.638346444836039
GO:0005313	L-glutamate transmembrane transporter activity	4/3556	14/18639	0.285714285714286	1.49758958701591	0.270464703579833	0.638346444836039
GO:0008474	palmitoyl-(protein) hydrolase activity	4/3556	14/18639	0.285714285714286	1.49758958701591	0.270464703579833	0.638346444836039
GO:0061665	SUMO ligase activity	4/3556	14/18639	0.285714285714286	1.49758958701591	0.270464703579833	0.638346444836039
GO:0098599	palmitoyl hydrolase activity	4/3556	14/18639	0.285714285714286	1.49758958701591	0.270464703579833	0.638346444836039
GO:0098821	BMP receptor activity	4/3556	14/18639	0.285714285714286	1.49758958701591	0.270464703579833	0.638346444836039
GO:1901612	cardiolipin binding	4/3556	14/18639	0.285714285714286	1.49758958701591	0.270464703579833	0.638346444836039
GO:0048487	beta-tubulin binding	10/3556	42/18639	0.238095238095238	1.24799132251326	0.270639766125242	0.638346444836039
GO:0098631	cell adhesion mediator activity	17/3556	76/18639	0.223684210526316	1.1724550056243	0.272711192004788	0.642097780117092
GO:0061749	forked DNA-dependent helicase activity	11/3556	47/18639	0.234042553191489	1.22674891702367	0.275825361058267	0.644395343369219
GO:1990518	single-stranded 3'-5' DNA helicase activity	11/3556	47/18639	0.234042553191489	1.22674891702367	0.275825361058267	0.644395343369219
GO:0019789	SUMO transferase activity	7/3556	28/18639	0.25	1.31039088863892	0.277239958310766	0.644395343369219
GO:0045499	chemorepellent activity	7/3556	28/18639	0.25	1.31039088863892	0.277239958310766	0.644395343369219
GO:0051119	sugar transmembrane transporter activity	7/3556	28/18639	0.25	1.31039088863892	0.277239958310766	0.644395343369219
GO:0051959	dynein light intermediate chain binding	7/3556	28/18639	0.25	1.31039088863892	0.277239958310766	0.644395343369219
GO:0097718	disordered domain specific binding	7/3556	28/18639	0.25	1.31039088863892	0.277239958310766	0.644395343369219
GO:0072341	modified amino acid binding	20/3556	91/18639	0.21978021978022	1.15199199001224	0.27754855613281	0.644395343369219
GO:0019239	deaminase activity	8/3556	33/18639	0.242424242424242	1.27068207383168	0.2856790624348	0.648833610746557
GO:0005520	insulin-like growth factor binding	5/3556	19/18639	0.263157894736842	1.37935883014623	0.289437720384267	0.648833610746557
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	5/3556	19/18639	0.263157894736842	1.37935883014623	0.289437720384267	0.648833610746557
GO:0042577	lipid phosphatase activity	5/3556	19/18639	0.263157894736842	1.37935883014623	0.289437720384267	0.648833610746557
GO:0050145	nucleoside monophosphate kinase activity	5/3556	19/18639	0.263157894736842	1.37935883014623	0.289437720384267	0.648833610746557
GO:0000146	microfilament motor activity	9/3556	38/18639	0.236842105263158	1.24142294713161	0.292070422682217	0.648833610746557
GO:0000182	rDNA binding	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0004090	carbonyl reductase (NADPH) activity	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0004955	prostaglandin receptor activity	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0005337	nucleoside transmembrane transporter activity	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0008140	cAMP response element binding protein binding	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0008190	eukaryotic initiation factor 4E binding	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0016868	intramolecular phosphotransferase activity	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0031957	very long-chain fatty acid-CoA ligase activity	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0031996	thioesterase binding	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0035374	chondroitin sulfate binding	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0042975	peroxisome proliferator activated receptor binding	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0043208	glycosphingolipid binding	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0043422	protein kinase B binding	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0051864	histone H3K36 demethylase activity	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0070097	delta-catenin binding	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0099122	RNA polymerase II C-terminal domain binding	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	3/3556	10/18639	0.3	1.5724690663667	0.294526717687201	0.648833610746557
GO:0015171	amino acid transmembrane transporter activity	22/3556	102/18639	0.215686274509804	1.13053331568848	0.296605357974886	0.652336330966183
GO:0009378	four-way junction helicase activity	11/3556	48/18639	0.229166666666667	1.20119164791901	0.300880513372554	0.658136030087174
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	11/3556	48/18639	0.229166666666667	1.20119164791901	0.300880513372554	0.658136030087174
GO:0043138	3'-5' DNA helicase activity	11/3556	48/18639	0.229166666666667	1.20119164791901	0.300880513372554	0.658136030087174
GO:0005315	phosphate transmembrane transporter activity	6/3556	24/18639	0.25	1.31039088863892	0.301707303680412	0.658136030087174
GO:0048027	mRNA 5'-UTR binding	6/3556	24/18639	0.25	1.31039088863892	0.301707303680412	0.658136030087174
GO:0038064	collagen receptor activity	12/3556	53/18639	0.226415094339623	1.18676910669185	0.303940912564775	0.659774176055243
GO:0051018	protein kinase A binding	12/3556	53/18639	0.226415094339623	1.18676910669185	0.303940912564775	0.659774176055243
GO:0140296	general transcription initiation factor binding	12/3556	53/18639	0.226415094339623	1.18676910669185	0.303940912564775	0.659774176055243
GO:0017116	single-stranded DNA helicase activity	13/3556	58/18639	0.224137931034483	1.17483321050386	0.306372186868392	0.663972190696921
GO:0030145	manganese ion binding	15/3556	68/18639	0.220588235294118	1.1562272546814	0.309837368327954	0.668928660819742
GO:0003785	actin monomer binding	7/3556	29/18639	0.241379310344828	1.26520499592723	0.310162427750876	0.668928660819742
GO:0035250	UDP-galactosyltransferase activity	7/3556	29/18639	0.241379310344828	1.26520499592723	0.310162427750876	0.668928660819742
GO:0001540	amyloid-beta binding	18/3556	83/18639	0.216867469879518	1.13672462628918	0.312684944189375	0.673281291117445
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	8/3556	34/18639	0.235294117647059	1.23330907166016	0.316223808478549	0.673793847264842
GO:0019825	oxygen binding	8/3556	34/18639	0.235294117647059	1.23330907166016	0.316223808478549	0.673793847264842
GO:0004467	long-chain fatty acid-CoA ligase activity	4/3556	15/18639	0.266666666666667	1.39775028121485	0.317465415677592	0.673793847264842
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/3556	15/18639	0.266666666666667	1.39775028121485	0.317465415677592	0.673793847264842
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/3556	15/18639	0.266666666666667	1.39775028121485	0.317465415677592	0.673793847264842
GO:0004865	protein serine/threonine phosphatase inhibitor activity	4/3556	15/18639	0.266666666666667	1.39775028121485	0.317465415677592	0.673793847264842
GO:0015556	C4-dicarboxylate transmembrane transporter activity	4/3556	15/18639	0.266666666666667	1.39775028121485	0.317465415677592	0.673793847264842
GO:0034483	heparan sulfate sulfotransferase activity	4/3556	15/18639	0.266666666666667	1.39775028121485	0.317465415677592	0.673793847264842
GO:0120283	protein serine/threonine kinase binding	4/3556	15/18639	0.266666666666667	1.39775028121485	0.317465415677592	0.673793847264842
GO:0016790	thiolester hydrolase activity	10/3556	44/18639	0.227272727272727	1.1912644442172	0.324000782377308	0.685485015013797
GO:0019205	nucleobase-containing compound kinase activity	10/3556	44/18639	0.227272727272727	1.1912644442172	0.324000782377308	0.685485015013797
GO:0001222	transcription corepressor binding	11/3556	49/18639	0.224489795918367	1.17667753265536	0.3264942532447	0.688577927459201
GO:0035254	glutamate receptor binding	11/3556	49/18639	0.224489795918367	1.17667753265536	0.3264942532447	0.688577927459201
GO:0000339	RNA cap binding	5/3556	20/18639	0.25	1.31039088863892	0.330386297447631	0.694591664712737
GO:0016004	phospholipase activator activity	5/3556	20/18639	0.25	1.31039088863892	0.330386297447631	0.694591664712737
GO:0003678	DNA helicase activity	16/3556	74/18639	0.216216216216216	1.13331103882285	0.331922290414769	0.695268835108981
GO:0008186	ATP-dependent activity, acting on RNA	17/3556	79/18639	0.215189873417722	1.12793139781578	0.332179981289224	0.695268835108981
GO:0004860	protein kinase inhibitor activity	18/3556	84/18639	0.214285714285714	1.12319219026193	0.332270799100772	0.695268835108981
GO:0019842	vitamin binding	31/3556	150/18639	0.206666666666667	1.08325646794151	0.34072196519141	0.706644983481869
GO:0008106	alcohol dehydrogenase (NADP+) activity	7/3556	30/18639	0.233333333333333	1.22303149606299	0.343757068441687	0.706644983481869
GO:0070566	adenylyltransferase activity	7/3556	30/18639	0.233333333333333	1.22303149606299	0.343757068441687	0.706644983481869
GO:0005539	glycosaminoglycan binding	49/3556	242/18639	0.202479338842975	1.06130832302987	0.345405353239137	0.706644983481869
GO:0005343	organic acid:sodium symporter activity	8/3556	35/18639	0.228571428571429	1.19807166961273	0.347352470029395	0.706644983481869
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	9/3556	40/18639	0.225	1.17935179977503	0.349806033120448	0.706644983481869
GO:0050997	quaternary ammonium group binding	9/3556	40/18639	0.225	1.17935179977503	0.349806033120448	0.706644983481869
GO:0004715	non-membrane spanning protein tyrosine kinase activity	10/3556	45/18639	0.222222222222222	1.16479190101237	0.351461636463843	0.706644983481869
GO:0019210	kinase inhibitor activity	19/3556	90/18639	0.211111111111111	1.10655230596175	0.351516962420337	0.706644983481869
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0004016	adenylate cyclase activity	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0004143	ATP-dependent diacylglycerol kinase activity	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0004954	prostanoid receptor activity	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0005225	volume-sensitive anion channel activity	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0005536	D-glucose binding	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0008046	axon guidance receptor activity	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0008432	JUN kinase binding	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0019215	intermediate filament binding	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0035252	UDP-xylosyltransferase activity	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0042285	xylosyltransferase activity	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0045294	alpha-catenin binding	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0070697	activin receptor binding	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0140031	phosphorylation-dependent protein binding	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/3556	11/18639	0.272727272727273	1.42951733306064	0.351999186528422	0.706644983481869
GO:0032813	tumor necrosis factor receptor superfamily binding	11/3556	50/18639	0.22	1.15314398200225	0.352538827943594	0.706665668625673
GO:0008028	monocarboxylic acid transmembrane transporter activity	15/3556	70/18639	0.214285714285714	1.12319219026193	0.353420270677685	0.70737040682865
GO:0000062	fatty-acyl-CoA binding	4/3556	16/18639	0.25	1.31039088863892	0.365011239127	0.719778440523699
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	4/3556	16/18639	0.25	1.31039088863892	0.365011239127	0.719778440523699
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	4/3556	16/18639	0.25	1.31039088863892	0.365011239127	0.719778440523699
GO:0005521	lamin binding	4/3556	16/18639	0.25	1.31039088863892	0.365011239127	0.719778440523699
GO:0008296	3'-5'-DNA exonuclease activity	4/3556	16/18639	0.25	1.31039088863892	0.365011239127	0.719778440523699
GO:0015378	sodium:chloride symporter activity	4/3556	16/18639	0.25	1.31039088863892	0.365011239127	0.719778440523699
GO:0022858	alanine transmembrane transporter activity	4/3556	16/18639	0.25	1.31039088863892	0.365011239127	0.719778440523699
GO:0097027	ubiquitin-protein transferase activator activity	4/3556	16/18639	0.25	1.31039088863892	0.365011239127	0.719778440523699
GO:0140327	flippase activity	4/3556	16/18639	0.25	1.31039088863892	0.365011239127	0.719778440523699
GO:0140328	floppase activity	4/3556	16/18639	0.25	1.31039088863892	0.365011239127	0.719778440523699
GO:0005126	cytokine receptor binding	55/3556	275/18639	0.2	1.04831271091114	0.371289176984477	0.729950359828233
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/3556	21/18639	0.238095238095238	1.24799132251326	0.37180992111101	0.729950359828233
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	5/3556	21/18639	0.238095238095238	1.24799132251326	0.37180992111101	0.729950359828233
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	6/3556	26/18639	0.230769230769231	1.20959158951285	0.375613195188726	0.731687595411758
GO:0008143	poly(A) binding	6/3556	26/18639	0.230769230769231	1.20959158951285	0.375613195188726	0.731687595411758
GO:0015145	monosaccharide transmembrane transporter activity	6/3556	26/18639	0.230769230769231	1.20959158951285	0.375613195188726	0.731687595411758
GO:0043548	phosphatidylinositol 3-kinase binding	6/3556	26/18639	0.230769230769231	1.20959158951285	0.375613195188726	0.731687595411758
GO:0047499	calcium-independent phospholipase A2 activity	7/3556	31/18639	0.225806451612903	1.18357886715773	0.377741651761828	0.731687595411758
GO:0072349	modified amino acid transmembrane transporter activity	7/3556	31/18639	0.225806451612903	1.18357886715773	0.377741651761828	0.731687595411758
GO:0004190	aspartic-type endopeptidase activity	8/3556	36/18639	0.222222222222222	1.16479190101237	0.378842547990422	0.731687595411758
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	8/3556	36/18639	0.222222222222222	1.16479190101237	0.378842547990422	0.731687595411758
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	8/3556	36/18639	0.222222222222222	1.16479190101237	0.378842547990422	0.731687595411758
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	8/3556	36/18639	0.222222222222222	1.16479190101237	0.378842547990422	0.731687595411758
GO:0030291	protein serine/threonine kinase inhibitor activity	10/3556	46/18639	0.217391304347826	1.13947033794689	0.379241493695624	0.731687595411758
GO:0015175	neutral L-amino acid transmembrane transporter activity	9/3556	41/18639	0.219512195121951	1.15058712173173	0.379271772303323	0.731687595411758
GO:0000287	magnesium ion binding	46/3556	230/18639	0.2	1.04831271091114	0.386232455691688	0.743462917524578
GO:0052689	carboxylic ester hydrolase activity	19/3556	92/18639	0.206521739130435	1.08249682104954	0.39072879332189	0.743462917524578
GO:0003724	RNA helicase activity	16/3556	77/18639	0.207792207792208	1.0891560632843	0.396178660195454	0.743462917524578
GO:0016500	protein-hormone receptor activity	14/3556	67/18639	0.208955223880597	1.09525208602656	0.399878902668794	0.743462917524578
GO:0015179	L-amino acid transmembrane transporter activity	13/3556	62/18639	0.209677419354839	1.09903751950361	0.401734883319824	0.743462917524578
GO:0070851	growth factor receptor binding	28/3556	139/18639	0.201438848920863	1.05585452897525	0.407682439742908	0.743462917524578
GO:0000340	RNA 7-methylguanosine cap binding	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0000995	RNA polymerase III general transcription initiation factor activity	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0004875	complement receptor activity	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0005247	voltage-gated chloride channel activity	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0005436	sodium:phosphate symporter activity	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0015132	prostaglandin transmembrane transporter activity	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0015166	polyol transmembrane transporter activity	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0016208	AMP binding	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0034452	dynactin binding	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0035197	siRNA binding	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0035497	cAMP response element binding	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0036009	protein-glutamine N-methyltransferase activity	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0070008	serine-type exopeptidase activity	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0070679	inositol 1,4,5 trisphosphate binding	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0097371	MDM2/MDM4 family protein binding	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0140829	bicarbonate:monoatomic anion antiporter activity	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0140900	chloride:bicarbonate antiporter activity	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0141221	histone deacetylase activity, hydrolytic mechanism	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:1990247	N6-methyladenosine-containing RNA reader activity	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:1990817	poly(A) RNA polymerase activity	3/3556	12/18639	0.25	1.31039088863892	0.408845344913621	0.743462917524578
GO:0051879	Hsp90 protein binding	9/3556	42/18639	0.214285714285714	1.12319219026193	0.408898683079163	0.743462917524578
GO:0019213	deacetylase activity	8/3556	37/18639	0.216216216216216	1.13331103882285	0.410478143386264	0.743462917524578
GO:0022829	wide pore channel activity	8/3556	37/18639	0.216216216216216	1.13331103882285	0.410478143386264	0.743462917524578
GO:0070001	aspartic-type peptidase activity	8/3556	37/18639	0.216216216216216	1.13331103882285	0.410478143386264	0.743462917524578
GO:0008378	galactosyltransferase activity	7/3556	32/18639	0.21875	1.14659202755906	0.411845239566554	0.743462917524578
GO:0015106	bicarbonate transmembrane transporter activity	7/3556	32/18639	0.21875	1.14659202755906	0.411845239566554	0.743462917524578
GO:0042910	xenobiotic transmembrane transporter activity	7/3556	32/18639	0.21875	1.14659202755906	0.411845239566554	0.743462917524578
GO:0120015	sterol transfer activity	7/3556	32/18639	0.21875	1.14659202755906	0.411845239566554	0.743462917524578
GO:0015103	inorganic anion transmembrane transporter activity	33/3556	165/18639	0.2	1.04831271091114	0.41200221210021	0.743462917524578
GO:0004029	aldehyde dehydrogenase (NAD+) activity	4/3556	17/18639	0.235294117647059	1.23330907166016	0.412367939003069	0.743462917524578
GO:0004550	nucleoside diphosphate kinase activity	4/3556	17/18639	0.235294117647059	1.23330907166016	0.412367939003069	0.743462917524578
GO:0008429	phosphatidylethanolamine binding	4/3556	17/18639	0.235294117647059	1.23330907166016	0.412367939003069	0.743462917524578
GO:0008484	sulfuric ester hydrolase activity	4/3556	17/18639	0.235294117647059	1.23330907166016	0.412367939003069	0.743462917524578
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	4/3556	17/18639	0.235294117647059	1.23330907166016	0.412367939003069	0.743462917524578
GO:0016805	dipeptidase activity	4/3556	17/18639	0.235294117647059	1.23330907166016	0.412367939003069	0.743462917524578
GO:0032183	SUMO binding	4/3556	17/18639	0.235294117647059	1.23330907166016	0.412367939003069	0.743462917524578
GO:0032977	membrane insertase activity	4/3556	17/18639	0.235294117647059	1.23330907166016	0.412367939003069	0.743462917524578
GO:0051787	misfolded protein binding	4/3556	17/18639	0.235294117647059	1.23330907166016	0.412367939003069	0.743462917524578
GO:0070403	NAD+ binding	4/3556	17/18639	0.235294117647059	1.23330907166016	0.412367939003069	0.743462917524578
GO:1901567	fatty acid derivative binding	4/3556	17/18639	0.235294117647059	1.23330907166016	0.412367939003069	0.743462917524578
GO:1990226	histone methyltransferase binding	4/3556	17/18639	0.235294117647059	1.23330907166016	0.412367939003069	0.743462917524578
GO:0008320	protein transmembrane transporter activity	6/3556	27/18639	0.222222222222222	1.16479190101237	0.412852048174928	0.743462917524578
GO:0030021	extracellular matrix structural constituent conferring compression resistance	5/3556	22/18639	0.227272727272727	1.1912644442172	0.413220587867593	0.743462917524578
GO:0031683	G-protein beta/gamma-subunit complex binding	5/3556	22/18639	0.227272727272727	1.1912644442172	0.413220587867593	0.743462917524578
GO:0032934	sterol binding	14/3556	68/18639	0.205882352941176	1.07914543770264	0.423223004164567	0.760434334535258
GO:0015297	antiporter activity	27/3556	135/18639	0.2	1.04831271091114	0.426492236131831	0.765040491558758
GO:0015399	primary active transmembrane transporter activity	33/3556	166/18639	0.198795180722892	1.04199757409842	0.426932708772491	0.765040491558758
GO:0004864	protein phosphatase inhibitor activity	11/3556	53/18639	0.207547169811321	1.0878716811342	0.431984022672374	0.773054517785012
GO:0140693	molecular condensate scaffold activity	10/3556	48/18639	0.208333333333333	1.0919924071991	0.43516845414048	0.777710691134593
GO:0051117	ATPase binding	17/3556	84/18639	0.202380952380952	1.06079262413627	0.436466460195578	0.778987599413231
GO:0046943	carboxylic acid transmembrane transporter activity	37/3556	188/18639	0.196808510638298	1.03158431658809	0.445664465459422	0.792929312405166
GO:0030296	protein tyrosine kinase activator activity	7/3556	33/18639	0.212121212121212	1.11184681460272	0.445813056486641	0.792929312405166
GO:0031072	heat shock protein binding	26/3556	131/18639	0.198473282442748	1.04031032380494	0.446059860386726	0.792929312405166
GO:0005242	inward rectifier potassium channel activity	6/3556	28/18639	0.214285714285714	1.12319219026193	0.449837163592427	0.794237739701544
GO:0016866	intramolecular transferase activity	6/3556	28/18639	0.214285714285714	1.12319219026193	0.449837163592427	0.794237739701544
GO:0046625	sphingolipid binding	6/3556	28/18639	0.214285714285714	1.12319219026193	0.449837163592427	0.794237739701544
GO:0050698	proteoglycan sulfotransferase activity	6/3556	28/18639	0.214285714285714	1.12319219026193	0.449837163592427	0.794237739701544
GO:0051019	mitogen-activated protein kinase binding	6/3556	28/18639	0.214285714285714	1.12319219026193	0.449837163592427	0.794237739701544
GO:0004602	glutathione peroxidase activity	5/3556	23/18639	0.217391304347826	1.13947033794689	0.454179712197814	0.794237739701544
GO:0005283	amino acid:sodium symporter activity	5/3556	23/18639	0.217391304347826	1.13947033794689	0.454179712197814	0.794237739701544
GO:0016493	C-C chemokine receptor activity	5/3556	23/18639	0.217391304347826	1.13947033794689	0.454179712197814	0.794237739701544
GO:0004879	nuclear receptor activity	12/3556	59/18639	0.203389830508475	1.06608072296048	0.454267947085215	0.794237739701544
GO:0005201	extracellular matrix structural constituent	33/3556	168/18639	0.196428571428571	1.02959284107344	0.456886502288709	0.794237739701544
GO:0000400	four-way junction DNA binding	4/3556	18/18639	0.222222222222222	1.16479190101237	0.458903959920149	0.794237739701544
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/3556	18/18639	0.222222222222222	1.16479190101237	0.458903959920149	0.794237739701544
GO:0008308	voltage-gated monoatomic anion channel activity	4/3556	18/18639	0.222222222222222	1.16479190101237	0.458903959920149	0.794237739701544
GO:0008409	5'-3' exonuclease activity	4/3556	18/18639	0.222222222222222	1.16479190101237	0.458903959920149	0.794237739701544
GO:0015172	acidic amino acid transmembrane transporter activity	4/3556	18/18639	0.222222222222222	1.16479190101237	0.458903959920149	0.794237739701544
GO:0015373	monoatomic anion:sodium symporter activity	4/3556	18/18639	0.222222222222222	1.16479190101237	0.458903959920149	0.794237739701544
GO:0005342	organic acid transmembrane transporter activity	37/3556	189/18639	0.195767195767196	1.0261261985109	0.459804878066585	0.794237739701544
GO:0048306	calcium-dependent protein binding	16/3556	80/18639	0.2	1.04831271091114	0.46142971595945	0.794237739701544
GO:0004465	lipoprotein lipase activity	3/3556	13/18639	0.230769230769231	1.20959158951285	0.464049016454835	0.794237739701544
GO:0008035	high-density lipoprotein particle binding	3/3556	13/18639	0.230769230769231	1.20959158951285	0.464049016454835	0.794237739701544
GO:0015651	quaternary ammonium group transmembrane transporter activity	3/3556	13/18639	0.230769230769231	1.20959158951285	0.464049016454835	0.794237739701544
GO:0030955	potassium ion binding	3/3556	13/18639	0.230769230769231	1.20959158951285	0.464049016454835	0.794237739701544
GO:0035673	oligopeptide transmembrane transporter activity	3/3556	13/18639	0.230769230769231	1.20959158951285	0.464049016454835	0.794237739701544
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	3/3556	13/18639	0.230769230769231	1.20959158951285	0.464049016454835	0.794237739701544
GO:0045159	myosin II binding	3/3556	13/18639	0.230769230769231	1.20959158951285	0.464049016454835	0.794237739701544
GO:0071837	HMG box domain binding	3/3556	13/18639	0.230769230769231	1.20959158951285	0.464049016454835	0.794237739701544
GO:0089720	caspase binding	3/3556	13/18639	0.230769230769231	1.20959158951285	0.464049016454835	0.794237739701544
GO:0097157	pre-mRNA intronic binding	3/3556	13/18639	0.230769230769231	1.20959158951285	0.464049016454835	0.794237739701544
GO:0140333	glycerophospholipid flippase activity	3/3556	13/18639	0.230769230769231	1.20959158951285	0.464049016454835	0.794237739701544
GO:0019783	ubiquitin-like protein peptidase activity	25/3556	127/18639	0.196850393700787	1.03180384932198	0.4663967121976	0.79723381662458
GO:0000217	DNA secondary structure binding	8/3556	39/18639	0.205128205128205	1.07519252401142	0.473376108219049	0.807097196005658
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	8/3556	39/18639	0.205128205128205	1.07519252401142	0.473376108219049	0.807097196005658
GO:0015081	sodium ion transmembrane transporter activity	32/3556	164/18639	0.195121951219512	1.02274410820599	0.475093151123793	0.808991526467174
GO:0008175	tRNA methyltransferase activity	7/3556	34/18639	0.205882352941176	1.07914543770264	0.479410268933183	0.811253022485289
GO:0015020	glucuronosyltransferase activity	7/3556	34/18639	0.205882352941176	1.07914543770264	0.479410268933183	0.811253022485289
GO:0051427	hormone receptor binding	7/3556	34/18639	0.205882352941176	1.07914543770264	0.479410268933183	0.811253022485289
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	12/3556	60/18639	0.2	1.04831271091114	0.479459651491306	0.811253022485289
GO:0098531	ligand-modulated transcription factor activity	12/3556	60/18639	0.2	1.04831271091114	0.479459651491306	0.811253022485289
GO:0005506	iron ion binding	30/3556	154/18639	0.194805194805195	1.02108380932903	0.481838610820172	0.814246260056874
GO:0015101	organic cation transmembrane transporter activity	16/3556	81/18639	0.197530864197531	1.03537057867767	0.483092076822602	0.815332392614631
GO:0008509	monoatomic anion transmembrane transporter activity	29/3556	149/18639	0.194630872483221	1.02017008779943	0.485371872067428	0.815547560749196
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	6/3556	29/18639	0.206896551724138	1.08446142508049	0.486274051203266	0.815547560749196
GO:0005416	amino acid:monoatomic cation symporter activity	6/3556	29/18639	0.206896551724138	1.08446142508049	0.486274051203266	0.815547560749196
GO:0097472	cyclin-dependent protein kinase activity	6/3556	29/18639	0.206896551724138	1.08446142508049	0.486274051203266	0.815547560749196
GO:0099604	ligand-gated calcium channel activity	6/3556	29/18639	0.206896551724138	1.08446142508049	0.486274051203266	0.815547560749196
GO:0005540	hyaluronic acid binding	5/3556	24/18639	0.208333333333333	1.0919924071991	0.494304030228709	0.82178814490078
GO:0015149	hexose transmembrane transporter activity	5/3556	24/18639	0.208333333333333	1.0919924071991	0.494304030228709	0.82178814490078
GO:0019957	C-C chemokine binding	5/3556	24/18639	0.208333333333333	1.0919924071991	0.494304030228709	0.82178814490078
GO:0035035	histone acetyltransferase binding	5/3556	24/18639	0.208333333333333	1.0919924071991	0.494304030228709	0.82178814490078
GO:0050699	WW domain binding	5/3556	24/18639	0.208333333333333	1.0919924071991	0.494304030228709	0.82178814490078
GO:0055056	D-glucose transmembrane transporter activity	5/3556	24/18639	0.208333333333333	1.0919924071991	0.494304030228709	0.82178814490078
GO:0060229	lipase activator activity	5/3556	24/18639	0.208333333333333	1.0919924071991	0.494304030228709	0.82178814490078
GO:0005346	purine ribonucleotide transmembrane transporter activity	4/3556	19/18639	0.210526315789474	1.10348706411699	0.504094957129718	0.831109403748874
GO:0022821	solute:potassium antiporter activity	4/3556	19/18639	0.210526315789474	1.10348706411699	0.504094957129718	0.831109403748874
GO:0031420	alkali metal ion binding	4/3556	19/18639	0.210526315789474	1.10348706411699	0.504094957129718	0.831109403748874
GO:0097001	ceramide binding	4/3556	19/18639	0.210526315789474	1.10348706411699	0.504094957129718	0.831109403748874
GO:0120227	acyl-CoA binding	4/3556	19/18639	0.210526315789474	1.10348706411699	0.504094957129718	0.831109403748874
GO:1990380	K48-linked deubiquitinase activity	4/3556	19/18639	0.210526315789474	1.10348706411699	0.504094957129718	0.831109403748874
GO:0071949	FAD binding	8/3556	40/18639	0.2	1.04831271091114	0.504268626993699	0.831109403748874
GO:0019212	phosphatase inhibitor activity	11/3556	56/18639	0.196428571428571	1.02959284107344	0.510857634847906	0.838381197360392
GO:0004623	phospholipase A2 activity	7/3556	35/18639	0.2	1.04831271091114	0.51242471865913	0.838381197360392
GO:0140566	histone reader activity	7/3556	35/18639	0.2	1.04831271091114	0.51242471865913	0.838381197360392
GO:0140375	immune receptor activity	30/3556	156/18639	0.192307692307692	1.00799299126071	0.513084721520868	0.838381197360392
GO:0008174	mRNA methyltransferase activity	3/3556	14/18639	0.214285714285714	1.12319219026193	0.516844738148017	0.838381197360392
GO:0008191	metalloendopeptidase inhibitor activity	3/3556	14/18639	0.214285714285714	1.12319219026193	0.516844738148017	0.838381197360392
GO:0008195	phosphatidate phosphatase activity	3/3556	14/18639	0.214285714285714	1.12319219026193	0.516844738148017	0.838381197360392
GO:0008331	high voltage-gated calcium channel activity	3/3556	14/18639	0.214285714285714	1.12319219026193	0.516844738148017	0.838381197360392
GO:0015386	potassium:proton antiporter activity	3/3556	14/18639	0.214285714285714	1.12319219026193	0.516844738148017	0.838381197360392
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/3556	14/18639	0.214285714285714	1.12319219026193	0.516844738148017	0.838381197360392
GO:0019763	immunoglobulin receptor activity	3/3556	14/18639	0.214285714285714	1.12319219026193	0.516844738148017	0.838381197360392
GO:0032036	myosin heavy chain binding	3/3556	14/18639	0.214285714285714	1.12319219026193	0.516844738148017	0.838381197360392
GO:0098847	sequence-specific single stranded DNA binding	3/3556	14/18639	0.214285714285714	1.12319219026193	0.516844738148017	0.838381197360392
GO:0033612	receptor serine/threonine kinase binding	6/3556	30/18639	0.2	1.04831271091114	0.521903296893661	0.844534425882469
GO:0048019	receptor antagonist activity	6/3556	30/18639	0.2	1.04831271091114	0.521903296893661	0.844534425882469
GO:0004180	carboxypeptidase activity	9/3556	46/18639	0.195652173913043	1.0255233041522	0.525754051252935	0.849735663949961
GO:0044325	transmembrane transporter binding	26/3556	136/18639	0.191176470588235	1.00206362072388	0.530101182745833	0.855664827861622
GO:0003707	nuclear steroid receptor activity	5/3556	25/18639	0.2	1.04831271091114	0.533268267251588	0.855664827861622
GO:0015662	P-type ion transporter activity	5/3556	25/18639	0.2	1.04831271091114	0.533268267251588	0.855664827861622
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	5/3556	25/18639	0.2	1.04831271091114	0.533268267251588	0.855664827861622
GO:0017025	TBP-class protein binding	5/3556	25/18639	0.2	1.04831271091114	0.533268267251588	0.855664827861622
GO:0140358	P-type transmembrane transporter activity	5/3556	25/18639	0.2	1.04831271091114	0.533268267251588	0.855664827861622
GO:0140828	metal cation:monoatomic cation antiporter activity	8/3556	41/18639	0.195121951219512	1.02274410820599	0.534570894797426	0.856725263570906
GO:0004033	aldo-keto reductase (NADPH) activity	7/3556	36/18639	0.194444444444444	1.01919291338583	0.544668690889508	0.86913440301673
GO:0015108	chloride transmembrane transporter activity	23/3556	121/18639	0.190082644628099	0.996330262436204	0.544679616346962	0.86913440301673
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	4/3556	20/18639	0.2	1.04831271091114	0.54752212205024	0.86913440301673
GO:0016505	peptidase activator activity involved in apoptotic process	4/3556	20/18639	0.2	1.04831271091114	0.54752212205024	0.86913440301673
GO:0030742	GTP-dependent protein binding	4/3556	20/18639	0.2	1.04831271091114	0.54752212205024	0.86913440301673
GO:0042288	MHC class I protein binding	4/3556	20/18639	0.2	1.04831271091114	0.54752212205024	0.86913440301673
GO:0061608	nuclear import signal receptor activity	4/3556	20/18639	0.2	1.04831271091114	0.54752212205024	0.86913440301673
GO:0140664	ATP-dependent DNA damage sensor activity	4/3556	20/18639	0.2	1.04831271091114	0.54752212205024	0.86913440301673
GO:1901681	sulfur compound binding	52/3556	275/18639	0.189090909090909	0.991132017588711	0.553299622178319	0.877262465092702
GO:0005164	tumor necrosis factor receptor binding	6/3556	31/18639	0.193548387096774	1.01449617184949	0.556502091725301	0.879207446690268
GO:0005452	solute:inorganic anion antiporter activity	6/3556	31/18639	0.193548387096774	1.01449617184949	0.556502091725301	0.879207446690268
GO:0070325	lipoprotein particle receptor binding	6/3556	31/18639	0.193548387096774	1.01449617184949	0.556502091725301	0.879207446690268
GO:0042277	peptide binding	47/3556	249/18639	0.188755020080321	0.989371433992438	0.558501578818353	0.881323413383571
GO:0016859	cis-trans isomerase activity	8/3556	42/18639	0.19047619047619	0.998393058010606	0.56414082696643	0.882152525160632
GO:0019894	kinesin binding	8/3556	42/18639	0.19047619047619	0.998393058010606	0.56414082696643	0.882152525160632
GO:0000774	adenyl-nucleotide exchange factor activity	3/3556	15/18639	0.2	1.04831271091114	0.566689568765624	0.882152525160632
GO:0004953	icosanoid receptor activity	3/3556	15/18639	0.2	1.04831271091114	0.566689568765624	0.882152525160632
GO:0017081	chloride channel regulator activity	3/3556	15/18639	0.2	1.04831271091114	0.566689568765624	0.882152525160632
GO:0031005	filamin binding	3/3556	15/18639	0.2	1.04831271091114	0.566689568765624	0.882152525160632
GO:0051371	muscle alpha-actinin binding	3/3556	15/18639	0.2	1.04831271091114	0.566689568765624	0.882152525160632
GO:0061578	K63-linked deubiquitinase activity	3/3556	15/18639	0.2	1.04831271091114	0.566689568765624	0.882152525160632
GO:0140161	monocarboxylate:sodium symporter activity	3/3556	15/18639	0.2	1.04831271091114	0.566689568765624	0.882152525160632
GO:0141050	histone H3K deacetylase activity	3/3556	15/18639	0.2	1.04831271091114	0.566689568765624	0.882152525160632
GO:0141051	histone H4K deacetylase activity	3/3556	15/18639	0.2	1.04831271091114	0.566689568765624	0.882152525160632
GO:0004529	DNA exonuclease activity	5/3556	26/18639	0.192307692307692	1.00799299126071	0.570805189171316	0.882152525160632
GO:0008157	protein phosphatase 1 binding	5/3556	26/18639	0.192307692307692	1.00799299126071	0.570805189171316	0.882152525160632
GO:0008198	ferrous iron binding	5/3556	26/18639	0.192307692307692	1.00799299126071	0.570805189171316	0.882152525160632
GO:0034237	protein kinase A regulatory subunit binding	5/3556	26/18639	0.192307692307692	1.00799299126071	0.570805189171316	0.882152525160632
GO:0050750	low-density lipoprotein particle receptor binding	5/3556	26/18639	0.192307692307692	1.00799299126071	0.570805189171316	0.882152525160632
GO:0051139	metal cation:proton antiporter activity	5/3556	26/18639	0.192307692307692	1.00799299126071	0.570805189171316	0.882152525160632
GO:0017046	peptide hormone binding	10/3556	53/18639	0.188679245283019	0.988974255576544	0.570921184823061	0.882152525160632
GO:0051087	protein-folding chaperone binding	25/3556	134/18639	0.186567164179104	0.977903648238	0.584499483403291	0.897704821165817
GO:0008373	sialyltransferase activity	4/3556	21/18639	0.19047619047619	0.998393058010606	0.588866169330058	0.897704821165817
GO:0009975	cyclase activity	4/3556	21/18639	0.19047619047619	0.998393058010606	0.588866169330058	0.897704821165817
GO:0070182	DNA polymerase binding	4/3556	21/18639	0.19047619047619	0.998393058010606	0.588866169330058	0.897704821165817
GO:0047498	calcium-dependent phospholipase A2 activity	6/3556	32/18639	0.1875	0.98279316647919	0.589884442223473	0.897704821165817
GO:0140142	nucleocytoplasmic carrier activity	6/3556	32/18639	0.1875	0.98279316647919	0.589884442223473	0.897704821165817
GO:0001094	TFIID-class transcription factor complex binding	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:0004862	cAMP-dependent protein kinase inhibitor activity	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:0005031	tumor necrosis factor receptor activity	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:0005381	iron ion transmembrane transporter activity	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:0015203	polyamine transmembrane transporter activity	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:0030957	Tat protein binding	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:0031434	mitogen-activated protein kinase kinase binding	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:0050308	sugar-phosphatase activity	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:0070513	death domain binding	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:0140940	histone H2A methyltransferase activity	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:0141109	transporter activator activity	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:1905394	retromer complex binding	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:1990259	histone H2AQ104 methyltransferase activity	2/3556	10/18639	0.2	1.04831271091114	0.595780128504055	0.897704821165817
GO:0140463	chromatin-protein adaptor activity	10/3556	54/18639	0.185185185185185	0.970659917510311	0.596473346747803	0.897736096852668
GO:0005109	frizzled binding	7/3556	38/18639	0.184210526315789	0.965551181102362	0.606221237397162	0.910055445460289
GO:0016405	CoA-ligase activity	5/3556	27/18639	0.185185185185185	0.970659917510311	0.606703630306859	0.910055445460289
GO:0035255	ionotropic glutamate receptor binding	5/3556	27/18639	0.185185185185185	0.970659917510311	0.606703630306859	0.910055445460289
GO:0004708	MAP kinase kinase activity	3/3556	16/18639	0.1875	0.98279316647919	0.613230721759151	0.91165146274885
GO:0005159	insulin-like growth factor receptor binding	3/3556	16/18639	0.1875	0.98279316647919	0.613230721759151	0.91165146274885
GO:0015385	sodium:proton antiporter activity	3/3556	16/18639	0.1875	0.98279316647919	0.613230721759151	0.91165146274885
GO:0016675	oxidoreductase activity, acting on a heme group of donors	3/3556	16/18639	0.1875	0.98279316647919	0.613230721759151	0.91165146274885
GO:0017070	U6 snRNA binding	3/3556	16/18639	0.1875	0.98279316647919	0.613230721759151	0.91165146274885
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/3556	16/18639	0.1875	0.98279316647919	0.613230721759151	0.91165146274885
GO:0055102	lipase inhibitor activity	3/3556	16/18639	0.1875	0.98279316647919	0.613230721759151	0.91165146274885
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	3/3556	16/18639	0.1875	0.98279316647919	0.613230721759151	0.91165146274885
GO:0030020	extracellular matrix structural constituent conferring tensile strength	8/3556	44/18639	0.181818181818182	0.95301155537376	0.620608741444057	0.920440031193936
GO:0140313	molecular sequestering activity	10/3556	55/18639	0.181818181818182	0.95301155537376	0.621285547760632	0.920440031193936
GO:0019956	chemokine binding	6/3556	33/18639	0.181818181818182	0.95301155537376	0.621900305720547	0.920440031193936
GO:0140311	protein sequestering activity	6/3556	33/18639	0.181818181818182	0.95301155537376	0.621900305720547	0.920440031193936
GO:0008970	phospholipase A1 activity	4/3556	22/18639	0.181818181818182	0.95301155537376	0.627898520766162	0.92419462538349
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	4/3556	22/18639	0.181818181818182	0.95301155537376	0.627898520766162	0.92419462538349
GO:0034062	5'-3' RNA polymerase activity	4/3556	22/18639	0.181818181818182	0.95301155537376	0.627898520766162	0.92419462538349
GO:0061133	endopeptidase activator activity	4/3556	22/18639	0.181818181818182	0.95301155537376	0.627898520766162	0.92419462538349
GO:0097747	RNA polymerase activity	4/3556	22/18639	0.181818181818182	0.95301155537376	0.627898520766162	0.92419462538349
GO:0016776	phosphotransferase activity, phosphate group as acceptor	7/3556	39/18639	0.179487179487179	0.940793458509994	0.635281109404873	0.933039527964146
GO:0003697	single-stranded DNA binding	22/3556	121/18639	0.181818181818182	0.95301155537376	0.63566909578954	0.933039527964146
GO:0051537	2 iron, 2 sulfur cluster binding	5/3556	28/18639	0.178571428571429	0.935993491884943	0.640805036114344	0.933039527964146
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	12/3556	67/18639	0.17910447761194	0.93878750230848	0.644900008641882	0.933039527964146
GO:0051539	4 iron, 4 sulfur cluster binding	8/3556	45/18639	0.177777777777778	0.931833520809899	0.647315809678169	0.933039527964146
GO:0000099	sulfur amino acid transmembrane transporter activity	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0002162	dystroglycan binding	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0003953	NAD+ nucleosidase activity	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0015173	aromatic amino acid transmembrane transporter activity	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0015217	ADP transmembrane transporter activity	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0016594	glycine binding	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0019107	myristoyltransferase activity	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0019203	carbohydrate phosphatase activity	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0019206	nucleoside kinase activity	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0019864	IgG binding	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0034056	estrogen response element binding	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0048407	platelet-derived growth factor binding	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0097493	structural molecule activity conferring elasticity	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0099528	G protein-coupled neurotransmitter receptor activity	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0180030	inositol phosphate kinase activity	2/3556	11/18639	0.181818181818182	0.95301155537376	0.649953671165307	0.933039527964146
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	6/3556	34/18639	0.176470588235294	0.92498180374512	0.652433885032125	0.933039527964146
GO:0005092	GDP-dissociation inhibitor activity	3/3556	17/18639	0.176470588235294	0.92498180374512	0.656272746635455	0.933039527964146
GO:0008569	minus-end-directed microtubule motor activity	3/3556	17/18639	0.176470588235294	0.92498180374512	0.656272746635455	0.933039527964146
GO:0009881	photoreceptor activity	3/3556	17/18639	0.176470588235294	0.92498180374512	0.656272746635455	0.933039527964146
GO:0015278	intracellularly gated calcium channel activity	3/3556	17/18639	0.176470588235294	0.92498180374512	0.656272746635455	0.933039527964146
GO:0015347	sodium-independent organic anion transmembrane transporter activity	3/3556	17/18639	0.176470588235294	0.92498180374512	0.656272746635455	0.933039527964146
GO:0016018	cyclosporin A binding	3/3556	17/18639	0.176470588235294	0.92498180374512	0.656272746635455	0.933039527964146
GO:0036041	long-chain fatty acid binding	3/3556	17/18639	0.176470588235294	0.92498180374512	0.656272746635455	0.933039527964146
GO:0045125	bioactive lipid receptor activity	3/3556	17/18639	0.176470588235294	0.92498180374512	0.656272746635455	0.933039527964146
GO:0045236	CXCR chemokine receptor binding	3/3556	17/18639	0.176470588235294	0.92498180374512	0.656272746635455	0.933039527964146
GO:0004518	nuclease activity	38/3556	209/18639	0.181818181818182	0.95301155537376	0.657352369911356	0.93358022748049
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	23/3556	128/18639	0.1796875	0.941843451209224	0.660672877559373	0.937298928312182
GO:0061791	GTPase motor activity	7/3556	40/18639	0.175	0.917273622047244	0.663071635976941	0.938696987857904
GO:1990606	membrane scission GTPase motor activity	7/3556	40/18639	0.175	0.917273622047244	0.663071635976941	0.938696987857904
GO:0000295	adenine nucleotide transmembrane transporter activity	4/3556	23/18639	0.173913043478261	0.91157627035751	0.664470901517393	0.938696987857904
GO:0005158	insulin receptor binding	4/3556	23/18639	0.173913043478261	0.91157627035751	0.664470901517393	0.938696987857904
GO:0140223	general transcription initiation factor activity	12/3556	68/18639	0.176470588235294	0.92498180374512	0.666167558026217	0.939604687678462
GO:0005200	structural constituent of cytoskeleton	20/3556	112/18639	0.178571428571429	0.935993491884943	0.666521078076032	0.939604687678462
GO:0003684	damaged DNA binding	13/3556	74/18639	0.175675675675676	0.920815219043566	0.675555131179292	0.951335548654383
GO:0005507	copper ion binding	11/3556	63/18639	0.174603174603175	0.915193636509722	0.677866682003857	0.95358484770827
GO:0000049	tRNA binding	14/3556	80/18639	0.175	0.917273622047244	0.684372983469049	0.959365440493619
GO:0004812	aminoacyl-tRNA ligase activity	7/3556	41/18639	0.170731707317073	0.894901094680238	0.689527670925665	0.959365440493619
GO:0008137	NADH dehydrogenase (ubiquinone) activity	7/3556	41/18639	0.170731707317073	0.894901094680238	0.689527670925665	0.959365440493619
GO:0016875	ligase activity, forming carbon-oxygen bonds	7/3556	41/18639	0.170731707317073	0.894901094680238	0.689527670925665	0.959365440493619
GO:0016877	ligase activity, forming carbon-sulfur bonds	7/3556	41/18639	0.170731707317073	0.894901094680238	0.689527670925665	0.959365440493619
GO:0004970	glutamate-gated receptor activity	3/3556	18/18639	0.166666666666667	0.87359392575928	0.695746503978516	0.959365440493619
GO:0015280	ligand-gated sodium channel activity	3/3556	18/18639	0.166666666666667	0.87359392575928	0.695746503978516	0.959365440493619
GO:0098641	cadherin binding involved in cell-cell adhesion	3/3556	18/18639	0.166666666666667	0.87359392575928	0.695746503978516	0.959365440493619
GO:0099095	ligand-gated monoatomic anion channel activity	8/3556	47/18639	0.170212765957447	0.892181030562669	0.697333025349926	0.959365440493619
GO:0004000	adenosine deaminase activity	2/3556	12/18639	0.166666666666667	0.87359392575928	0.698175336415645	0.959365440493619
GO:0004126	cytidine deaminase activity	2/3556	12/18639	0.166666666666667	0.87359392575928	0.698175336415645	0.959365440493619
GO:0004859	phospholipase inhibitor activity	2/3556	12/18639	0.166666666666667	0.87359392575928	0.698175336415645	0.959365440493619
GO:0005049	nuclear export signal receptor activity	2/3556	12/18639	0.166666666666667	0.87359392575928	0.698175336415645	0.959365440493619
GO:0005078	MAP-kinase scaffold activity	2/3556	12/18639	0.166666666666667	0.87359392575928	0.698175336415645	0.959365440493619
GO:0016273	arginine N-methyltransferase activity	2/3556	12/18639	0.166666666666667	0.87359392575928	0.698175336415645	0.959365440493619
GO:0016274	protein-arginine N-methyltransferase activity	2/3556	12/18639	0.166666666666667	0.87359392575928	0.698175336415645	0.959365440493619
GO:0016840	carbon-nitrogen lyase activity	2/3556	12/18639	0.166666666666667	0.87359392575928	0.698175336415645	0.959365440493619
GO:0043047	single-stranded telomeric DNA binding	2/3556	12/18639	0.166666666666667	0.87359392575928	0.698175336415645	0.959365440493619
GO:0001091	RNA polymerase II general transcription initiation factor binding	4/3556	24/18639	0.166666666666667	0.87359392575928	0.698504275775129	0.959365440493619
GO:0004806	triacylglycerol lipase activity	4/3556	24/18639	0.166666666666667	0.87359392575928	0.698504275775129	0.959365440493619
GO:0030552	cAMP binding	4/3556	24/18639	0.166666666666667	0.87359392575928	0.698504275775129	0.959365440493619
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	4/3556	24/18639	0.166666666666667	0.87359392575928	0.698504275775129	0.959365440493619
GO:0140612	DNA damage sensor activity	4/3556	24/18639	0.166666666666667	0.87359392575928	0.698504275775129	0.959365440493619
GO:0016251	RNA polymerase II general transcription initiation factor activity	9/3556	53/18639	0.169811320754717	0.890076830018889	0.704812496222343	0.965488102197123
GO:0020037	heme binding	25/3556	142/18639	0.176056338028169	0.922810484956986	0.705422364410416	0.965488102197123
GO:0005262	calcium channel activity	23/3556	131/18639	0.175572519083969	0.920274517212066	0.705428846249739	0.965488102197123
GO:0097110	scaffold protein binding	12/3556	70/18639	0.171428571428571	0.898553752209545	0.706460000465537	0.965488102197123
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	6/3556	36/18639	0.166666666666667	0.87359392575928	0.708747820339461	0.965488102197123
GO:0044390	ubiquitin-like protein conjugating enzyme binding	6/3556	36/18639	0.166666666666667	0.87359392575928	0.708747820339461	0.965488102197123
GO:0045505	dynein intermediate chain binding	6/3556	36/18639	0.166666666666667	0.87359392575928	0.708747820339461	0.965488102197123
GO:0055106	ubiquitin-protein transferase regulator activity	6/3556	36/18639	0.166666666666667	0.87359392575928	0.708747820339461	0.965488102197123
GO:0140098	catalytic activity, acting on RNA	70/3556	387/18639	0.180878552971576	0.948086431056583	0.711431680837077	0.967911924270711
GO:0070888	E-box binding	10/3556	59/18639	0.169491525423729	0.888400602467064	0.711977160774411	0.967911924270711
GO:0008307	structural constituent of muscle	7/3556	42/18639	0.166666666666667	0.87359392575928	0.714605039717512	0.970496162790314
GO:0160215	deacylase activity	11/3556	65/18639	0.169230769230769	0.887033832309423	0.718844081230018	0.975261024839506
GO:0004519	endonuclease activity	22/3556	127/18639	0.173228346456693	0.907987387403346	0.727031946231049	0.98478215488888
GO:0016651	oxidoreductase activity, acting on NAD(P)H	15/3556	88/18639	0.170454545454545	0.8934483331629	0.727337232000327	0.98478215488888
GO:0008139	nuclear localization sequence binding	4/3556	25/18639	0.16	0.838650168728909	0.729977801208185	0.985359317101038
GO:0015645	fatty acid ligase activity	4/3556	25/18639	0.16	0.838650168728909	0.729977801208185	0.985359317101038
GO:0120515	fatty acid-CoA ligase activity	4/3556	25/18639	0.16	0.838650168728909	0.729977801208185	0.985359317101038
GO:0016878	acid-thiol ligase activity	5/3556	31/18639	0.161290322580645	0.845413476541239	0.731432752967203	0.985665348770847
GO:0008381	mechanosensitive monoatomic ion channel activity	3/3556	19/18639	0.157894736842105	0.827615298087739	0.731681169012666	0.985665348770847
GO:0002161	aminoacyl-tRNA editing activity	2/3556	13/18639	0.153846153846154	0.806394393008566	0.740743758226701	0.989882800032678
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/3556	13/18639	0.153846153846154	0.806394393008566	0.740743758226701	0.989882800032678
GO:0005035	death receptor activity	2/3556	13/18639	0.153846153846154	0.806394393008566	0.740743758226701	0.989882800032678
GO:0005542	folic acid binding	2/3556	13/18639	0.153846153846154	0.806394393008566	0.740743758226701	0.989882800032678
GO:0008417	fucosyltransferase activity	2/3556	13/18639	0.153846153846154	0.806394393008566	0.740743758226701	0.989882800032678
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/3556	13/18639	0.153846153846154	0.806394393008566	0.740743758226701	0.989882800032678
GO:0031994	insulin-like growth factor I binding	2/3556	13/18639	0.153846153846154	0.806394393008566	0.740743758226701	0.989882800032678
GO:0061459	L-arginine transmembrane transporter activity	2/3556	13/18639	0.153846153846154	0.806394393008566	0.740743758226701	0.989882800032678
GO:0060590	ATPase regulator activity	8/3556	49/18639	0.163265306122449	0.855765478294805	0.742554842434537	0.991310714650106
GO:0031369	translation initiation factor binding	5/3556	32/18639	0.15625	0.818994305399325	0.75764540310493	1
GO:0005516	calmodulin binding	36/3556	207/18639	0.173913043478261	0.91157627035751	0.758373138938393	1
GO:0015216	purine nucleotide transmembrane transporter activity	4/3556	26/18639	0.153846153846154	0.806394393008566	0.758918276123979	1
GO:0030247	polysaccharide binding	4/3556	26/18639	0.153846153846154	0.806394393008566	0.758918276123979	1
GO:0097602	cullin family protein binding	4/3556	26/18639	0.153846153846154	0.806394393008566	0.758918276123979	1
GO:0003954	NADH dehydrogenase activity	7/3556	44/18639	0.159090909090909	0.83388511095204	0.760540534572633	1
GO:0030547	signaling receptor inhibitor activity	7/3556	44/18639	0.159090909090909	0.83388511095204	0.760540534572633	1
GO:0046906	tetrapyrrole binding	26/3556	152/18639	0.171052631578947	0.896583239595051	0.762726170562136	1
GO:0001972	retinoic acid binding	3/3556	20/18639	0.15	0.786234533183352	0.764179824358976	1
GO:0043024	ribosomal small subunit binding	3/3556	20/18639	0.15	0.786234533183352	0.764179824358976	1
GO:0140939	histone H4 methyltransferase activity	3/3556	20/18639	0.15	0.786234533183352	0.764179824358976	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	22/3556	130/18639	0.169230769230769	0.887033832309423	0.767017137273481	1
GO:0004175	endopeptidase activity	72/3556	405/18639	0.177777777777778	0.931833520809899	0.767786832939288	1
GO:0033218	amide binding	43/3556	247/18639	0.174089068825911	0.91249891840443	0.772336782673383	1
GO:0003774	cytoskeletal motor activity	26/3556	153/18639	0.169934640522876	0.890723218421227	0.774401583592434	1
GO:0005347	ATP transmembrane transporter activity	2/3556	14/18639	0.142857142857143	0.748794793507954	0.778060261573148	1
GO:0008494	translation activator activity	2/3556	14/18639	0.142857142857143	0.748794793507954	0.778060261573148	1
GO:0016530	metallochaperone activity	2/3556	14/18639	0.142857142857143	0.748794793507954	0.778060261573148	1
GO:0019992	diacylglycerol binding	2/3556	14/18639	0.142857142857143	0.748794793507954	0.778060261573148	1
GO:0042043	neurexin family protein binding	2/3556	14/18639	0.142857142857143	0.748794793507954	0.778060261573148	1
GO:0043176	amine binding	2/3556	14/18639	0.142857142857143	0.748794793507954	0.778060261573148	1
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/3556	14/18639	0.142857142857143	0.748794793507954	0.778060261573148	1
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/3556	14/18639	0.142857142857143	0.748794793507954	0.778060261573148	1
GO:0046873	metal ion transmembrane transporter activity	80/3556	450/18639	0.177777777777778	0.931833520809899	0.778350612560942	1
GO:0042605	peptide antigen binding	7/3556	45/18639	0.155555555555556	0.815354330708661	0.781397720737403	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	5/3556	33/18639	0.151515151515152	0.7941762961448	0.781885599066427	1
GO:0004722	protein serine/threonine phosphatase activity	17/3556	103/18639	0.16504854368932	0.865112431334433	0.783068952168073	1
GO:0001671	ATPase activator activity	4/3556	27/18639	0.148148148148148	0.776527934008249	0.78539038844	1
GO:0005104	fibroblast growth factor receptor binding	4/3556	27/18639	0.148148148148148	0.776527934008249	0.78539038844	1
GO:0008395	steroid hydroxylase activity	4/3556	27/18639	0.148148148148148	0.776527934008249	0.78539038844	1
GO:0003924	GTPase activity	58/3556	331/18639	0.175226586102719	0.918461287505225	0.785888717708945	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	22/3556	132/18639	0.166666666666667	0.87359392575928	0.791424890734107	1
GO:0005248	voltage-gated sodium channel activity	3/3556	21/18639	0.142857142857143	0.748794793507954	0.793398766863796	1
GO:0015174	basic amino acid transmembrane transporter activity	3/3556	21/18639	0.142857142857143	0.748794793507954	0.793398766863796	1
GO:0035613	RNA stem-loop binding	3/3556	21/18639	0.142857142857143	0.748794793507954	0.793398766863796	1
GO:0051428	peptide hormone receptor binding	3/3556	21/18639	0.142857142857143	0.748794793507954	0.793398766863796	1
GO:1904047	S-adenosyl-L-methionine binding	3/3556	21/18639	0.142857142857143	0.748794793507954	0.793398766863796	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	9/3556	58/18639	0.155172413793103	0.813346068810364	0.802260928333886	1
GO:0009055	electron transfer activity	19/3556	116/18639	0.163793103448276	0.858531961522051	0.803592434527684	1
GO:0030332	cyclin binding	5/3556	34/18639	0.147058823529412	0.7708181697876	0.804204860106824	1
GO:0017022	myosin binding	12/3556	76/18639	0.157894736842105	0.827615298087739	0.808072474494292	1
GO:0051536	iron-sulfur cluster binding	12/3556	76/18639	0.157894736842105	0.827615298087739	0.808072474494292	1
GO:0004129	cytochrome-c oxidase activity	2/3556	15/18639	0.133333333333333	0.698875140607424	0.810578829697383	1
GO:0005523	tropomyosin binding	2/3556	15/18639	0.133333333333333	0.698875140607424	0.810578829697383	1
GO:0008020	G protein-coupled photoreceptor activity	2/3556	15/18639	0.133333333333333	0.698875140607424	0.810578829697383	1
GO:0008242	omega peptidase activity	2/3556	15/18639	0.133333333333333	0.698875140607424	0.810578829697383	1
GO:0010181	FMN binding	2/3556	15/18639	0.133333333333333	0.698875140607424	0.810578829697383	1
GO:0015250	water channel activity	2/3556	15/18639	0.133333333333333	0.698875140607424	0.810578829697383	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/3556	15/18639	0.133333333333333	0.698875140607424	0.810578829697383	1
GO:0031386	protein tag activity	2/3556	15/18639	0.133333333333333	0.698875140607424	0.810578829697383	1
GO:0033130	acetylcholine receptor binding	2/3556	15/18639	0.133333333333333	0.698875140607424	0.810578829697383	1
GO:0045504	dynein heavy chain binding	2/3556	15/18639	0.133333333333333	0.698875140607424	0.810578829697383	1
GO:0050700	CARD domain binding	2/3556	15/18639	0.133333333333333	0.698875140607424	0.810578829697383	1
GO:0140776	protein-containing complex destabilizing activity	2/3556	15/18639	0.133333333333333	0.698875140607424	0.810578829697383	1
GO:0141047	molecular tag activity	2/3556	15/18639	0.133333333333333	0.698875140607424	0.810578829697383	1
GO:0042562	hormone binding	15/3556	94/18639	0.159574468085106	0.836419716152502	0.815684778635361	1
GO:0005246	calcium channel regulator activity	8/3556	53/18639	0.150943396226415	0.791179404461235	0.818318213929999	1
GO:0008146	sulfotransferase activity	8/3556	53/18639	0.150943396226415	0.791179404461235	0.818318213929999	1
GO:0005243	gap junction channel activity	3/3556	22/18639	0.136363636363636	0.71475866653032	0.819530384668686	1
GO:0042287	MHC protein binding	6/3556	41/18639	0.146341463414634	0.76705808115449	0.820904827204756	1
GO:0046982	protein heterodimerization activity	64/3556	369/18639	0.173441734417344	0.909105873960877	0.821577777613382	1
GO:0051540	metal cluster binding	12/3556	77/18639	0.155844155844156	0.816867047463223	0.822161034523174	1
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	13/3556	83/18639	0.156626506024096	0.820967785653299	0.823985726575912	1
GO:0005254	chloride channel activity	13/3556	83/18639	0.156626506024096	0.820967785653299	0.823985726575912	1
GO:0004181	metallocarboxypeptidase activity	4/3556	29/18639	0.137931034482759	0.72297428338699	0.831326180098029	1
GO:0106222	lncRNA binding	4/3556	29/18639	0.137931034482759	0.72297428338699	0.831326180098029	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	8/3556	54/18639	0.148148148148148	0.776527934008249	0.834290020506129	1
GO:0038187	pattern recognition receptor activity	7/3556	48/18639	0.145833333333333	0.76439468503937	0.835795013661689	1
GO:0003688	DNA replication origin binding	2/3556	16/18639	0.125	0.65519544431946	0.838771416545702	1
GO:0022841	potassium ion leak channel activity	2/3556	16/18639	0.125	0.65519544431946	0.838771416545702	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/3556	16/18639	0.125	0.65519544431946	0.838771416545702	1
GO:0004857	enzyme inhibitor activity	72/3556	416/18639	0.173076923076923	0.907193692134637	0.839561838530717	1
GO:0016849	phosphorus-oxygen lyase activity	3/3556	23/18639	0.130434782608696	0.683682202768132	0.84278930714138	1
GO:0031681	G-protein beta-subunit binding	3/3556	23/18639	0.130434782608696	0.683682202768132	0.84278930714138	1
GO:0005525	GTP binding	65/3556	378/18639	0.171957671957672	0.901327066259575	0.843192071484201	1
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	9/3556	61/18639	0.147540983606557	0.773345442475428	0.847923810664196	1
GO:0033293	monocarboxylic acid binding	12/3556	79/18639	0.151898734177215	0.796186869046433	0.84798518502137	1
GO:0015215	nucleotide transmembrane transporter activity	4/3556	30/18639	0.133333333333333	0.698875140607424	0.851035110853687	1
GO:0031624	ubiquitin conjugating enzyme binding	4/3556	30/18639	0.133333333333333	0.698875140607424	0.851035110853687	1
GO:0005253	monoatomic anion channel activity	16/3556	103/18639	0.155339805825243	0.814223464785348	0.852513036136031	1
GO:0004540	RNA nuclease activity	19/3556	121/18639	0.15702479338843	0.823055434186429	0.857360623789726	1
GO:0003777	microtubule motor activity	10/3556	68/18639	0.147058823529412	0.7708181697876	0.86014931449605	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	10/3556	68/18639	0.147058823529412	0.7708181697876	0.86014931449605	1
GO:0030551	cyclic nucleotide binding	5/3556	37/18639	0.135135135135135	0.708319399264281	0.860389077937399	1
GO:0004659	prenyltransferase activity	2/3556	17/18639	0.117647058823529	0.61665453583008	0.863104572533734	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/3556	17/18639	0.117647058823529	0.61665453583008	0.863104572533734	1
GO:0048038	quinone binding	2/3556	17/18639	0.117647058823529	0.61665453583008	0.863104572533734	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	3/3556	24/18639	0.125	0.65519544431946	0.863401454479416	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	3/3556	24/18639	0.125	0.65519544431946	0.863401454479416	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	3/3556	24/18639	0.125	0.65519544431946	0.863401454479416	1
GO:0070840	dynein complex binding	3/3556	24/18639	0.125	0.65519544431946	0.863401454479416	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	19/3556	122/18639	0.155737704918033	0.816309078168508	0.866626026686312	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/3556	31/18639	0.129032258064516	0.676330781232991	0.868753978688722	1
GO:0033192	calmodulin-dependent protein phosphatase activity	12/3556	81/18639	0.148148148148148	0.776527934008249	0.870801990889972	1
GO:0140791	histone H2AXS140 phosphatase activity	12/3556	81/18639	0.148148148148148	0.776527934008249	0.870801990889972	1
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	12/3556	81/18639	0.148148148148148	0.776527934008249	0.870801990889972	1
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	12/3556	81/18639	0.148148148148148	0.776527934008249	0.870801990889972	1
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	12/3556	81/18639	0.148148148148148	0.776527934008249	0.870801990889972	1
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	12/3556	81/18639	0.148148148148148	0.776527934008249	0.870801990889972	1
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	12/3556	81/18639	0.148148148148148	0.776527934008249	0.870801990889972	1
GO:1990439	MAP kinase serine/threonine phosphatase activity	12/3556	81/18639	0.148148148148148	0.776527934008249	0.870801990889972	1
GO:0005501	retinoid binding	5/3556	38/18639	0.131578947368421	0.689679415073116	0.875828819922136	1
GO:0019840	isoprenoid binding	5/3556	38/18639	0.131578947368421	0.689679415073116	0.875828819922136	1
GO:0005272	sodium channel activity	7/3556	51/18639	0.137254901960784	0.71943029180176	0.878835787869907	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0008401	retinoic acid 4-hydroxylase activity	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0015187	glycine transmembrane transporter activity	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0015279	store-operated calcium channel activity	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0016427	tRNA (cytidine) methyltransferase activity	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0016783	sulfurtransferase activity	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0031419	cobalamin binding	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0032052	bile acid binding	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0032395	MHC class II receptor activity	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0035256	G protein-coupled glutamate receptor binding	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0043121	neurotrophin binding	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0043295	glutathione binding	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0047429	nucleoside triphosphate diphosphatase activity	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0050815	phosphoserine residue binding	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0051378	serotonin binding	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0097177	mitochondrial ribosome binding	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0098505	G-rich strand telomeric DNA binding	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0140135	mechanosensitive monoatomic cation channel activity	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:1990757	ubiquitin ligase activator activity	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:1990763	arrestin family protein binding	1/3556	10/18639	0.1	0.524156355455568	0.879661683000951	1
GO:0015085	calcium ion transmembrane transporter activity	23/3556	147/18639	0.156462585034014	0.820108583365855	0.880608748070233	1
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	12/3556	82/18639	0.146341463414634	0.76705808115449	0.881140565956278	1
GO:0033549	MAP kinase phosphatase activity	12/3556	82/18639	0.146341463414634	0.76705808115449	0.881140565956278	1
GO:0047617	fatty acyl-CoA hydrolase activity	3/3556	25/18639	0.12	0.628987626546682	0.881595589016402	1
GO:0016782	transferase activity, transferring sulphur-containing groups	10/3556	70/18639	0.142857142857143	0.748794793507954	0.883029116344441	1
GO:0008009	chemokine activity	6/3556	45/18639	0.133333333333333	0.698875140607424	0.88339003899817	1
GO:0000900	mRNA regulatory element binding translation repressor activity	2/3556	18/18639	0.111111111111111	0.582395950506187	0.884024331103137	1
GO:0005372	water transmembrane transporter activity	2/3556	18/18639	0.111111111111111	0.582395950506187	0.884024331103137	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/3556	18/18639	0.111111111111111	0.582395950506187	0.884024331103137	1
GO:0031690	adrenergic receptor binding	2/3556	18/18639	0.111111111111111	0.582395950506187	0.884024331103137	1
GO:0050811	GABA receptor binding	2/3556	18/18639	0.111111111111111	0.582395950506187	0.884024331103137	1
GO:0070064	proline-rich region binding	2/3556	18/18639	0.111111111111111	0.582395950506187	0.884024331103137	1
GO:0070628	proteasome binding	2/3556	18/18639	0.111111111111111	0.582395950506187	0.884024331103137	1
GO:0099602	neurotransmitter receptor regulator activity	2/3556	18/18639	0.111111111111111	0.582395950506187	0.884024331103137	1
GO:1990381	ubiquitin-specific protease binding	2/3556	18/18639	0.111111111111111	0.582395950506187	0.884024331103137	1
GO:0004867	serine-type endopeptidase inhibitor activity	14/3556	95/18639	0.147368421052632	0.77244094488189	0.889914388400152	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	7/3556	52/18639	0.134615384615385	0.705595093882495	0.890914756475079	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	6/3556	46/18639	0.130434782608696	0.683682202768132	0.895768003147211	1
GO:0005112	Notch binding	3/3556	26/18639	0.115384615384615	0.604795794756425	0.897596977654544	1
GO:0005227	calcium-activated cation channel activity	3/3556	26/18639	0.115384615384615	0.604795794756425	0.897596977654544	1
GO:0008066	glutamate receptor activity	3/3556	26/18639	0.115384615384615	0.604795794756425	0.897596977654544	1
GO:0016289	acyl-CoA hydrolase activity	3/3556	26/18639	0.115384615384615	0.604795794756425	0.897596977654544	1
GO:0019865	immunoglobulin binding	3/3556	26/18639	0.115384615384615	0.604795794756425	0.897596977654544	1
GO:0030507	spectrin binding	3/3556	26/18639	0.115384615384615	0.604795794756425	0.897596977654544	1
GO:0019001	guanyl nucleotide binding	67/3556	400/18639	0.1675	0.877961895388077	0.898082779122981	1
GO:0032561	guanyl ribonucleotide binding	67/3556	400/18639	0.1675	0.877961895388077	0.898082779122981	1
GO:0005496	steroid binding	16/3556	108/18639	0.148148148148148	0.776527934008249	0.898168694552982	1
GO:0017018	myosin phosphatase activity	12/3556	84/18639	0.142857142857143	0.748794793507954	0.899809520282025	1
GO:0180051	translation factor activity	12/3556	84/18639	0.142857142857143	0.748794793507954	0.899809520282025	1
GO:0015078	proton transmembrane transporter activity	29/3556	185/18639	0.156756756756757	0.821650503146566	0.90177548573076	1
GO:0008301	DNA binding, bending	2/3556	19/18639	0.105263157894737	0.551743532058493	0.901947056054957	1
GO:0008574	plus-end-directed microtubule motor activity	2/3556	19/18639	0.105263157894737	0.551743532058493	0.901947056054957	1
GO:0016918	retinal binding	2/3556	19/18639	0.105263157894737	0.551743532058493	0.901947056054957	1
GO:0022840	leak channel activity	2/3556	19/18639	0.105263157894737	0.551743532058493	0.901947056054957	1
GO:0022842	narrow pore channel activity	2/3556	19/18639	0.105263157894737	0.551743532058493	0.901947056054957	1
GO:0034987	immunoglobulin receptor binding	2/3556	19/18639	0.105263157894737	0.551743532058493	0.901947056054957	1
GO:0042834	peptidoglycan binding	2/3556	19/18639	0.105263157894737	0.551743532058493	0.901947056054957	1
GO:0001851	complement component C3b binding	1/3556	11/18639	0.0909090909090909	0.47650577768688	0.902632484184515	1
GO:0008503	benzodiazepine receptor activity	1/3556	11/18639	0.0909090909090909	0.47650577768688	0.902632484184515	1
GO:0032404	mismatch repair complex binding	1/3556	11/18639	0.0909090909090909	0.47650577768688	0.902632484184515	1
GO:0034511	U3 snoRNA binding	1/3556	11/18639	0.0909090909090909	0.47650577768688	0.902632484184515	1
GO:0042608	T cell receptor binding	1/3556	11/18639	0.0909090909090909	0.47650577768688	0.902632484184515	1
GO:0050786	RAGE receptor binding	1/3556	11/18639	0.0909090909090909	0.47650577768688	0.902632484184515	1
GO:0050998	nitric-oxide synthase binding	1/3556	11/18639	0.0909090909090909	0.47650577768688	0.902632484184515	1
GO:0070990	snRNP binding	1/3556	11/18639	0.0909090909090909	0.47650577768688	0.902632484184515	1
GO:1900750	oligopeptide binding	1/3556	11/18639	0.0909090909090909	0.47650577768688	0.902632484184515	1
GO:0061134	peptidase regulator activity	36/3556	226/18639	0.15929203539823	0.834939327274356	0.905032049820353	1
GO:0051082	unfolded protein binding	18/3556	121/18639	0.148760330578512	0.779736727123986	0.905856025383555	1
GO:0005504	fatty acid binding	6/3556	47/18639	0.127659574468085	0.669135772922002	0.907003911331807	1
GO:0004364	glutathione transferase activity	3/3556	27/18639	0.111111111111111	0.582395950506187	0.911622801306362	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	3/3556	27/18639	0.111111111111111	0.582395950506187	0.911622801306362	1
GO:0017069	snRNA binding	7/3556	54/18639	0.12962962962963	0.679461942257218	0.912040870288234	1
GO:0001530	lipopolysaccharide binding	5/3556	41/18639	0.121951219512195	0.639215067628741	0.913693874782328	1
GO:0017080	sodium channel regulator activity	5/3556	41/18639	0.121951219512195	0.639215067628741	0.913693874782328	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/3556	20/18639	0.1	0.524156355455568	0.917254526243399	1
GO:0015464	acetylcholine receptor activity	2/3556	20/18639	0.1	0.524156355455568	0.917254526243399	1
GO:0003720	telomerase activity	1/3556	12/18639	0.0833333333333333	0.43679696287964	0.921219497618049	1
GO:0004032	aldose reductase (NADPH) activity	1/3556	12/18639	0.0833333333333333	0.43679696287964	0.921219497618049	1
GO:0004300	enoyl-CoA hydratase activity	1/3556	12/18639	0.0833333333333333	0.43679696287964	0.921219497618049	1
GO:0005095	GTPase inhibitor activity	1/3556	12/18639	0.0833333333333333	0.43679696287964	0.921219497618049	1
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/3556	12/18639	0.0833333333333333	0.43679696287964	0.921219497618049	1
GO:0015269	calcium-activated potassium channel activity	1/3556	12/18639	0.0833333333333333	0.43679696287964	0.921219497618049	1
GO:0015368	calcium:monoatomic cation antiporter activity	1/3556	12/18639	0.0833333333333333	0.43679696287964	0.921219497618049	1
GO:0016423	tRNA (guanine) methyltransferase activity	1/3556	12/18639	0.0833333333333333	0.43679696287964	0.921219497618049	1
GO:0042301	phosphate ion binding	1/3556	12/18639	0.0833333333333333	0.43679696287964	0.921219497618049	1
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/3556	12/18639	0.0833333333333333	0.43679696287964	0.921219497618049	1
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/3556	12/18639	0.0833333333333333	0.43679696287964	0.921219497618049	1
GO:1990459	transferrin receptor binding	1/3556	12/18639	0.0833333333333333	0.43679696287964	0.921219497618049	1
GO:0042056	chemoattractant activity	5/3556	42/18639	0.119047619047619	0.623995661256629	0.923838795907963	1
GO:0022853	active monoatomic ion transmembrane transporter activity	17/3556	118/18639	0.144067796610169	0.755140512097005	0.925322031629037	1
GO:0043022	ribosome binding	16/3556	112/18639	0.142857142857143	0.748794793507954	0.925791173168174	1
GO:0019003	GDP binding	10/3556	75/18639	0.133333333333333	0.698875140607424	0.927067787065466	1
GO:0015125	bile acid transmembrane transporter activity	2/3556	21/18639	0.0952380952380952	0.499196529005303	0.930291974599147	1
GO:0016874	ligase activity	25/3556	167/18639	0.149700598802395	0.784665202777796	0.930878853355517	1
GO:0005245	voltage-gated calcium channel activity	5/3556	43/18639	0.116279069767442	0.609484134250661	0.932910576439578	1
GO:0008200	ion channel inhibitor activity	5/3556	43/18639	0.116279069767442	0.609484134250661	0.932910576439578	1
GO:0048020	CCR chemokine receptor binding	6/3556	50/18639	0.12	0.628987626546682	0.93464122327163	1
GO:0005179	hormone activity	19/3556	132/18639	0.143939393939394	0.75446748133756	0.935528742742126	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/3556	13/18639	0.0769230769230769	0.403197196504283	0.936259142567327	1
GO:0003964	RNA-directed DNA polymerase activity	1/3556	13/18639	0.0769230769230769	0.403197196504283	0.936259142567327	1
GO:0009982	pseudouridine synthase activity	1/3556	13/18639	0.0769230769230769	0.403197196504283	0.936259142567327	1
GO:0019855	calcium channel inhibitor activity	1/3556	13/18639	0.0769230769230769	0.403197196504283	0.936259142567327	1
GO:0031432	titin binding	1/3556	13/18639	0.0769230769230769	0.403197196504283	0.936259142567327	1
GO:0032396	inhibitory MHC class I receptor activity	1/3556	13/18639	0.0769230769230769	0.403197196504283	0.936259142567327	1
GO:0035325	Toll-like receptor binding	1/3556	13/18639	0.0769230769230769	0.403197196504283	0.936259142567327	1
GO:0070700	BMP receptor binding	1/3556	13/18639	0.0769230769230769	0.403197196504283	0.936259142567327	1
GO:0015276	ligand-gated monoatomic ion channel activity	28/3556	186/18639	0.150537634408602	0.789052578105156	0.936369582332027	1
GO:0008135	translation factor activity, RNA binding	11/3556	83/18639	0.132530120481928	0.694665049398946	0.937957283578812	1
GO:0016248	channel inhibitor activity	5/3556	44/18639	0.113636363636364	0.5956322221086	0.941002821722848	1
GO:0008093	cytoskeletal anchor activity	2/3556	22/18639	0.0909090909090909	0.47650577768688	0.941368133592193	1
GO:0033691	sialic acid binding	2/3556	22/18639	0.0909090909090909	0.47650577768688	0.941368133592193	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/3556	30/18639	0.1	0.524156355455568	0.943838491529781	1
GO:0022839	monoatomic ion-gated channel activity	3/3556	30/18639	0.1	0.524156355455568	0.943838491529781	1
GO:0022834	ligand-gated channel activity	28/3556	188/18639	0.148936170212766	0.780658401742335	0.944351897866208	1
GO:0019843	rRNA binding	8/3556	65/18639	0.123076923076923	0.645115514406853	0.946177341076472	1
GO:0141110	transporter inhibitor activity	5/3556	45/18639	0.111111111111111	0.582395950506187	0.948204419563433	1
GO:0008392	arachidonate epoxygenase activity	1/3556	14/18639	0.0714285714285714	0.374397396753977	0.948428287259187	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/3556	14/18639	0.0714285714285714	0.374397396753977	0.948428287259187	1
GO:0030983	mismatched DNA binding	1/3556	14/18639	0.0714285714285714	0.374397396753977	0.948428287259187	1
GO:0034236	protein kinase A catalytic subunit binding	1/3556	14/18639	0.0714285714285714	0.374397396753977	0.948428287259187	1
GO:0044548	S100 protein binding	1/3556	14/18639	0.0714285714285714	0.374397396753977	0.948428287259187	1
GO:0071933	Arp2/3 complex binding	1/3556	14/18639	0.0714285714285714	0.374397396753977	0.948428287259187	1
GO:1901474	azole transmembrane transporter activity	1/3556	14/18639	0.0714285714285714	0.374397396753977	0.948428287259187	1
GO:1990825	sequence-specific mRNA binding	1/3556	14/18639	0.0714285714285714	0.374397396753977	0.948428287259187	1
GO:0042379	chemokine receptor binding	9/3556	72/18639	0.125	0.65519544431946	0.948658273154184	1
GO:0015459	potassium channel regulator activity	7/3556	59/18639	0.11864406779661	0.621880421726945	0.950076100682469	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/3556	23/18639	0.0869565217391304	0.455788135178755	0.950756593254175	1
GO:0005212	structural constituent of eye lens	2/3556	23/18639	0.0869565217391304	0.455788135178755	0.950756593254175	1
GO:0043274	phospholipase binding	2/3556	23/18639	0.0869565217391304	0.455788135178755	0.950756593254175	1
GO:0099094	ligand-gated monoatomic cation channel activity	19/3556	136/18639	0.139705882352941	0.73227726129822	0.953065200107885	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	9/3556	73/18639	0.123287671232877	0.646220164260289	0.95388057018858	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/3556	39/18639	0.102564102564103	0.537596262005711	0.955704506007272	1
GO:0004497	monooxygenase activity	14/3556	106/18639	0.132075471698113	0.69228197890358	0.957472883497816	1
GO:0004089	carbonate dehydratase activity	1/3556	15/18639	0.0666666666666667	0.349437570303712	0.958274677085031	1
GO:0016846	carbon-sulfur lyase activity	1/3556	15/18639	0.0666666666666667	0.349437570303712	0.958274677085031	1
GO:0030553	cGMP binding	1/3556	15/18639	0.0666666666666667	0.349437570303712	0.958274677085031	1
GO:0048531	beta-1,3-galactosyltransferase activity	1/3556	15/18639	0.0666666666666667	0.349437570303712	0.958274677085031	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/3556	24/18639	0.0833333333333333	0.43679696287964	0.958697969506426	1
GO:0050661	NADP binding	6/3556	54/18639	0.111111111111111	0.582395950506187	0.960065708558575	1
GO:0016836	hydro-lyase activity	7/3556	61/18639	0.114754098360656	0.601490899703111	0.960607394734869	1
GO:0071855	neuropeptide receptor binding	4/3556	40/18639	0.1	0.524156355455568	0.961629658088873	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/3556	25/18639	0.08	0.419325084364454	0.965402524331645	1
GO:0008391	arachidonate monooxygenase activity	1/3556	16/18639	0.0625	0.32759772215973	0.966241561120986	1
GO:0016722	oxidoreductase activity, acting on metal ions	1/3556	16/18639	0.0625	0.32759772215973	0.966241561120986	1
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/3556	16/18639	0.0625	0.32759772215973	0.966241561120986	1
GO:0016831	carboxy-lyase activity	3/3556	34/18639	0.0882352941176471	0.46249090187256	0.970016269973157	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	2/3556	26/18639	0.0769230769230769	0.403197196504283	0.971052986554737	1
GO:0030548	acetylcholine receptor regulator activity	1/3556	17/18639	0.0588235294117647	0.30832726791504	0.972687622907689	1
GO:0070492	oligosaccharide binding	1/3556	17/18639	0.0588235294117647	0.30832726791504	0.972687622907689	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	4/3556	43/18639	0.0930232558139535	0.487587307400528	0.975276396621925	1
GO:0016830	carbon-carbon lyase activity	5/3556	51/18639	0.0980392156862745	0.5138787798584	0.977017450149755	1
GO:0001664	G protein-coupled receptor binding	44/3556	297/18639	0.148148148148148	0.776527934008249	0.977665340344372	1
GO:0022851	GABA-gated chloride ion channel activity	1/3556	18/18639	0.0555555555555556	0.291197975253093	0.977903110660898	1
GO:0032393	MHC class I receptor activity	1/3556	18/18639	0.0555555555555556	0.291197975253093	0.977903110660898	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/3556	36/18639	0.0833333333333333	0.43679696287964	0.978275432929486	1
GO:0004521	RNA endonuclease activity	8/3556	73/18639	0.10958904109589	0.574417923786924	0.978707812312641	1
GO:0140101	catalytic activity, acting on a tRNA	18/3556	139/18639	0.129496402877698	0.6787636257698	0.97883495251079	1
GO:0036002	pre-mRNA binding	6/3556	59/18639	0.101694915254237	0.533040361480239	0.979103301947455	1
GO:0061135	endopeptidase regulator activity	25/3556	184/18639	0.135869565217391	0.712168961216804	0.980666240050661	1
GO:0023023	MHC protein complex binding	3/3556	37/18639	0.0810810810810811	0.424991639558569	0.9815425795047	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/3556	19/18639	0.0526315789473684	0.275871766029246	0.982122891472339	1
GO:0004890	GABA-A receptor activity	1/3556	19/18639	0.0526315789473684	0.275871766029246	0.982122891472339	1
GO:0030506	ankyrin binding	1/3556	19/18639	0.0526315789473684	0.275871766029246	0.982122891472339	1
GO:0070003	threonine-type peptidase activity	1/3556	19/18639	0.0526315789473684	0.275871766029246	0.982122891472339	1
GO:0099589	serotonin receptor activity	1/3556	19/18639	0.0526315789473684	0.275871766029246	0.982122891472339	1
GO:0099106	ion channel regulator activity	21/3556	160/18639	0.13125	0.687955216535433	0.982268822219147	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	5/3556	53/18639	0.0943396226415094	0.494487127788272	0.982658826096501	1
GO:0004866	endopeptidase inhibitor activity	21/3556	161/18639	0.130434782608696	0.683682202768132	0.98375786565731	1
GO:0016247	channel regulator activity	22/3556	168/18639	0.130952380952381	0.686395227382292	0.9846908381626	1
GO:0016408	C-acyltransferase activity	1/3556	20/18639	0.05	0.262078177727784	0.985537015958073	1
GO:0008236	serine-type peptidase activity	26/3556	194/18639	0.134020618556701	0.702477589785813	0.985798811446854	1
GO:0030414	peptidase inhibitor activity	22/3556	169/18639	0.130177514792899	0.682333717161094	0.985972271665726	1
GO:0141108	transporter regulator activity	22/3556	170/18639	0.129411764705882	0.678319989413088	0.987155554251677	1
GO:0022824	transmitter-gated monoatomic ion channel activity	6/3556	63/18639	0.0952380952380952	0.499196529005303	0.98782832592926	1
GO:0022835	transmitter-gated channel activity	6/3556	63/18639	0.0952380952380952	0.499196529005303	0.98782832592926	1
GO:0043021	ribonucleoprotein complex binding	23/3556	177/18639	0.129943502824859	0.681107128558083	0.987875997612932	1
GO:0001846	opsonin binding	1/3556	21/18639	0.0476190476190476	0.249598264502651	0.988299268026019	1
GO:0008188	neuropeptide receptor activity	4/3556	48/18639	0.0833333333333333	0.43679696287964	0.98841890458049	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	4/3556	48/18639	0.0833333333333333	0.43679696287964	0.98841890458049	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	5/3556	56/18639	0.0892857142857143	0.467996745942471	0.988735421213297	1
GO:0140662	ATP-dependent protein folding chaperone	3/3556	40/18639	0.075	0.393117266591676	0.98875732739668	1
GO:0017171	serine hydrolase activity	26/3556	198/18639	0.131313131313131	0.688286123325494	0.989836237306058	1
GO:0016835	carbon-oxygen lyase activity	8/3556	79/18639	0.10126582278481	0.530791246030955	0.989890283709157	1
GO:0030515	snoRNA binding	2/3556	32/18639	0.0625	0.32759772215973	0.990276429040535	1
GO:0016881	acid-amino acid ligase activity	1/3556	22/18639	0.0454545454545455	0.23825288884344	0.99053408395144	1
GO:0022832	voltage-gated channel activity	22/3556	175/18639	0.125714285714286	0.658939418287	0.991818377906926	1
GO:0042923	neuropeptide binding	2/3556	33/18639	0.0606060606060606	0.31767051845792	0.991917156954145	1
GO:0016917	GABA receptor activity	1/3556	23/18639	0.0434782608695652	0.227894067589377	0.992342151710406	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/3556	23/18639	0.0434782608695652	0.227894067589377	0.992342151710406	1
GO:0044183	protein folding chaperone	7/3556	75/18639	0.0933333333333333	0.489212598425197	0.99346563492264	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/3556	24/18639	0.0416666666666667	0.21839848143982	0.993804942241014	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/3556	24/18639	0.0416666666666667	0.21839848143982	0.993804942241014	1
GO:0098960	postsynaptic neurotransmitter receptor activity	6/3556	69/18639	0.0869565217391304	0.455788135178755	0.994761609239532	1
GO:0001848	complement binding	1/3556	25/18639	0.04	0.209662542182227	0.994988376320571	1
GO:0015271	outward rectifier potassium channel activity	1/3556	25/18639	0.04	0.209662542182227	0.994988376320571	1
GO:0008083	growth factor activity	19/3556	162/18639	0.117283950617284	0.614751281089864	0.99567756571205	1
GO:0023026	MHC class II protein complex binding	1/3556	27/18639	0.037037037037037	0.194131983502062	0.996720345393381	1
GO:0005244	voltage-gated monoatomic ion channel activity	20/3556	173/18639	0.115606936416185	0.605961104572911	0.997220243332435	1
GO:0004252	serine-type endopeptidase activity	20/3556	176/18639	0.113636363636364	0.5956322221086	0.9979608615168	1
GO:0008528	G protein-coupled peptide receptor activity	12/3556	122/18639	0.0983606557377049	0.515563628316952	0.998290503040857	1
GO:0003743	translation initiation factor activity	3/3556	51/18639	0.0588235294117647	0.30832726791504	0.998299621627061	1
GO:0005184	neuropeptide hormone activity	1/3556	31/18639	0.032258064516129	0.169082695308248	0.998595695504535	1
GO:0015079	potassium ion transmembrane transporter activity	17/3556	160/18639	0.10625	0.556916127671541	0.998749235285941	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/3556	32/18639	0.03125	0.163798861079865	0.998864058938857	1
GO:0160041	neuropeptide activity	1/3556	32/18639	0.03125	0.163798861079865	0.998864058938857	1
GO:0030594	neurotransmitter receptor activity	8/3556	97/18639	0.0824742268041237	0.432293901406654	0.999114942863195	1
GO:0001653	peptide receptor activity	12/3556	128/18639	0.09375	0.491396583239595	0.999196107138141	1
GO:0005249	voltage-gated potassium channel activity	8/3556	98/18639	0.0816326530612245	0.427882739147402	0.999232682010654	1
GO:0022843	voltage-gated monoatomic cation channel activity	14/3556	143/18639	0.0979020979020979	0.513160068278179	0.999238103228123	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	1/3556	34/18639	0.0294117647058824	0.15416363395752	0.999256761360286	1
GO:0022836	gated channel activity	40/3556	318/18639	0.125786163522013	0.659316170384362	0.999292996531209	1
GO:0005125	cytokine activity	27/3556	234/18639	0.115384615384615	0.604795794756425	0.999342255440449	1
GO:0016229	steroid dehydrogenase activity	1/3556	35/18639	0.0285714285714286	0.149758958701591	0.999398817614133	1
GO:0030280	structural constituent of skin epidermis	1/3556	37/18639	0.027027027027027	0.141663879852856	0.999606680358856	1
GO:0016829	lyase activity	21/3556	200/18639	0.105	0.550364173228346	0.999681311076461	1
GO:0003735	structural constituent of ribosome	17/3556	175/18639	0.0971428571428571	0.509180459585409	0.999784007774021	1
GO:0005267	potassium channel activity	10/3556	124/18639	0.0806451612903226	0.422706738270619	0.999821954130967	1
GO:0008227	G protein-coupled amine receptor activity	1/3556	41/18639	0.024390243902439	0.127843013525748	0.999831671290992	1
GO:0005261	monoatomic cation channel activity	41/3556	341/18639	0.120234604105572	0.630217318876196	0.999839749349736	1
GO:0005216	monoatomic ion channel activity	57/3556	448/18639	0.127232142857143	0.666895362968022	0.999888247521651	1
GO:0003730	mRNA 3'-UTR binding	28/3556	262/18639	0.106870229007634	0.560167097433432	0.999927927296761	1
GO:0030527	structural constituent of chromatin	2/3556	98/18639	0.0204081632653061	0.106970684786851	0.999999977666458	1
GO:0003823	antigen binding	9/3556	174/18639	0.0517241379310345	0.271115356270121	0.999999981033321	1
GO:0005549	odorant binding	1/3556	111/18639	0.00900900900900901	0.0472212932842854	0.999999999942251	1
GO:0004984	olfactory receptor activity	4/3556	419/18639	0.00954653937947494	0.0500387928835864	1	1
GO:0030371	translation repressor activity	8/3556	329/18639	0.0243161094224924	0.127454432937524	1	1
GO:0045182	translation regulator activity	13/3556	356/18639	0.0365168539325843	0.191405410700067	1	1