ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 128/1939 175/18639 0.731428571428571 7.03099388491859 3.08517049997461e-87 3.59422363247042e-84 GO:0009055 electron transfer activity 57/1939 116/18639 0.491379310344828 4.72347548505273 5.58517230862806e-26 3.25336286977584e-23 GO:0019843 rRNA binding 39/1939 65/18639 0.6 5.76761217122228 2.16797235357604e-22 8.41895930638695e-20 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 38/1939 68/18639 0.558823529411765 5.37179564966781 2.4887005510949e-20 7.24834035506388e-18 GO:0015078 proton transmembrane transporter activity 65/1939 185/18639 0.351351351351351 3.37743055071575 1.26955312830989e-19 2.95805878896205e-17 GO:0022853 active monoatomic ion transmembrane transporter activity 46/1939 118/18639 0.389830508474576 3.74731864231956 2.76009605686623e-16 5.31666310557306e-14 GO:0008137 NADH dehydrogenase (ubiquinone) activity 26/1939 41/18639 0.634146341463415 6.09585026226745 3.19456152266193e-16 5.31666310557306e-14 GO:0003954 NADH dehydrogenase activity 26/1939 44/18639 0.590909090909091 5.68022410802194 3.79493553019552e-15 5.39713899904923e-13 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 30/1939 58/18639 0.517241379310345 4.97207945795024 4.16946360441571e-15 5.39713899904923e-13 GO:0043021 ribonucleoprotein complex binding 52/1939 177/18639 0.293785310734463 2.82406622319735 1.94284754950481e-12 2.26341739517311e-10 GO:0008135 translation factor activity, RNA binding 33/1939 83/18639 0.397590361445783 3.82191167972561 2.30657672126233e-12 2.44287443660965e-10 GO:0180051 translation factor activity 33/1939 84/18639 0.392857142857143 3.77641273115744 3.42247667749225e-12 3.32265444106539e-10 GO:0015399 primary active transmembrane transporter activity 48/1939 166/18639 0.289156626506024 2.77957213070953 2.55299464883493e-11 2.28787597376361e-09 GO:0016651 oxidoreductase activity, acting on NAD(P)H 32/1939 88/18639 0.363636363636364 3.4955225280135 8.01620053583664e-11 6.6706240173212e-09 GO:0051082 unfolded protein binding 37/1939 121/18639 0.305785123966942 2.93941667128408 8.51113360589174e-10 6.61031376724258e-08 GO:0003743 translation initiation factor activity 22/1939 51/18639 0.431372549019608 4.14664927342778 1.66585320810294e-09 1.21294936714995e-07 GO:0045296 cadherin binding 69/1939 334/18639 0.206586826347305 1.9858544900915 1.82400105819215e-08 1.24997719576109e-06 GO:0003697 single-stranded DNA binding 34/1939 121/18639 0.28099173553719 2.70108558982862 4.32383307305016e-08 2.79848085005746e-06 GO:0044389 ubiquitin-like protein ligase binding 66/1939 322/18639 0.204968944099379 1.97030229451693 5.07745625913736e-08 3.11328239047107e-06 GO:0051087 protein-folding chaperone binding 36/1939 134/18639 0.26865671641791 2.58251291248759 6.21679205188469e-08 3.62128137022283e-06 GO:0051540 metal cluster binding 25/1939 77/18639 0.324675324675325 3.12100225715491 1.23162592891374e-07 6.83259146278337e-06 GO:0140662 ATP-dependent protein folding chaperone 17/1939 40/18639 0.425 4.08539195461578 1.55437592180091e-07 8.23112704044571e-06 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 11/1939 18/18639 0.611111111111111 5.87441980402269 2.38798851371941e-07 1.20956809499266e-05 GO:0055105 ubiquitin-protein transferase inhibitor activity 10/1939 15/18639 0.666666666666667 6.40845796802475 2.66534226113849e-07 1.29380155592764e-05 GO:0044183 protein folding chaperone 24/1939 75/18639 0.32 3.07605982465188 2.97422132454101e-07 1.38598713723611e-05 GO:0051536 iron-sulfur cluster binding 24/1939 76/18639 0.315789473684211 3.03558535327488 3.9212910639409e-07 1.75704003441967e-05 GO:0031625 ubiquitin protein ligase binding 60/1939 302/18639 0.198675496688742 1.90980535470936 6.19265334843047e-07 2.67201524108204e-05 GO:0031072 heat shock protein binding 33/1939 131/18639 0.251908396946565 2.42151656043683 1.07795251554934e-06 4.4850524307678e-05 GO:0055106 ubiquitin-protein transferase regulator activity 15/1939 36/18639 0.416666666666667 4.00528623001547 1.13966070195716e-06 4.57829213027618e-05 GO:0048027 mRNA 5'-UTR binding 12/1939 24/18639 0.5 4.80634347601857 1.2688042509775e-06 4.92718984129596e-05 GO:0051537 2 iron, 2 sulfur cluster binding 13/1939 28/18639 0.464285714285714 4.46303322773153 1.33546324014091e-06 5.01875701536825e-05 GO:1990948 ubiquitin ligase inhibitor activity 8/1939 11/18639 0.727272727272727 6.99104505602701 1.67237669871864e-06 6.08849641877253e-05 GO:0043022 ribosome binding 29/1939 112/18639 0.258928571428571 2.48899930008104 2.61909669057752e-06 9.24620498340245e-05 GO:0003684 damaged DNA binding 22/1939 74/18639 0.297297297297297 2.85782585060563 3.65882558165053e-06 0.000125368582430084 GO:0003688 DNA replication origin binding 9/1939 16/18639 0.5625 5.40713641052089 8.10957367059405e-06 0.000269932952178345 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 29/1939 122/18639 0.237704918032787 2.28498296400883 1.58981141945452e-05 0.00051448063990681 GO:0070182 DNA polymerase binding 10/1939 21/18639 0.476190476190476 4.57746997716054 1.73681891190452e-05 0.000546863251991557 GO:0003712 transcription coregulator activity 81/1939 495/18639 0.163636363636364 1.57298513760608 2.43716403644386e-05 0.000747183184857131 GO:0061133 endopeptidase activator activity 10/1939 22/18639 0.454545454545455 4.36940316001688 2.88733954990365e-05 0.000837715855694326 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 30/1939 132/18639 0.227272727272727 2.18470158000844 2.88992181409456e-05 0.000837715855694326 GO:0070990 snRNP binding 7/1939 11/18639 0.636363636363636 6.11716442402363 2.9481845565208e-05 0.000837715855694326 GO:0016853 isomerase activity 37/1939 180/18639 0.205555555555556 1.97594120680763 3.90102664744939e-05 0.00108207048673299 GO:0015252 proton channel activity 11/1939 27/18639 0.407407407407407 3.91627986934846 4.01973251849147e-05 0.00108906706605641 GO:0004601 peroxidase activity 17/1939 57/18639 0.298245614035088 2.86694172253739 4.36343570892084e-05 0.00110083913943979 GO:0004129 cytochrome-c oxidase activity 8/1939 15/18639 0.533333333333333 5.1267663744198 4.44115360975711e-05 0.00110083913943979 GO:0031386 protein tag activity 8/1939 15/18639 0.533333333333333 5.1267663744198 4.44115360975711e-05 0.00110083913943979 GO:0141047 molecular tag activity 8/1939 15/18639 0.533333333333333 5.1267663744198 4.44115360975711e-05 0.00110083913943979 GO:0031491 nucleosome binding 20/1939 74/18639 0.27027027027027 2.59802350055058 4.66017215006127e-05 0.00113106261558779 GO:0008301 DNA binding, bending 9/1939 19/18639 0.473684210526316 4.55337802991233 4.89492204089684e-05 0.00116273451350763 GO:0016209 antioxidant activity 22/1939 86/18639 0.255813953488372 2.45905945284671 4.99027688200698e-05 0.00116273451350763 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 17/1939 59/18639 0.288135593220339 2.76975725736663 7.08568713261737e-05 0.00161859323715671 GO:0016675 oxidoreductase activity, acting on a heme group of donors 8/1939 16/18639 0.5 4.80634347601857 8.0713498524548e-05 0.00180829280348266 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 17/1939 61/18639 0.278688524590164 2.67894554401035 0.000112030722811558 0.00246256211463142 GO:0140297 DNA-binding transcription factor binding 77/1939 488/18639 0.157786885245902 1.51675593300586 0.000130315947801282 0.00281144591089803 GO:0016504 peptidase activator activity 16/1939 57/18639 0.280701754385965 2.6982980917999 0.00016116750157087 0.00341382071509208 GO:0031492 nucleosomal DNA binding 13/1939 42/18639 0.30952380952381 2.97535548515435 0.000225606883306153 0.00463339306507905 GO:0003746 translation elongation factor activity 8/1939 18/18639 0.444444444444444 4.2723053120165 0.000226698201467387 0.00463339306507905 GO:0030515 snoRNA binding 11/1939 32/18639 0.34375 3.30436113976276 0.000243439309547754 0.0048897723383299 GO:0003714 transcription corepressor activity 38/1939 204/18639 0.186274509803922 1.79059854988927 0.000270252356295177 0.0053363388997268 GO:0051287 NAD binding 15/1939 54/18639 0.277777777777778 2.67019082001031 0.000290499400385121 0.00564053002414443 GO:0019864 IgG binding 6/1939 11/18639 0.545454545454545 5.24328379202025 0.00036576205719111 0.00698545568242037 GO:0043024 ribosomal small subunit binding 8/1939 20/18639 0.4 3.84507478081485 0.000539424284468684 0.0101359563130003 GO:0042826 histone deacetylase binding 26/1939 127/18639 0.204724409448819 1.96795165947217 0.000554641497200123 0.0102564657815578 GO:0003713 transcription coactivator activity 44/1939 256/18639 0.171875 1.65218056988138 0.000583367222134658 0.0106191064654199 GO:0017070 U6 snRNA binding 7/1939 16/18639 0.4375 4.20555054151625 0.000638295607409849 0.0114402212712688 GO:0017116 single-stranded DNA helicase activity 15/1939 58/18639 0.258620689655172 2.48603972897512 0.000670083877766287 0.0118279957211776 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 13/1939 48/18639 0.270833333333333 2.60343604951006 0.00094235928109799 0.0163857994399874 GO:0017069 snRNA binding 14/1939 54/18639 0.259259259259259 2.49217809867629 0.000975729879501046 0.0165898424593512 GO:0022804 active transmembrane transporter activity 69/1939 457/18639 0.150984682713348 1.45136848947607 0.00098257436025342 0.0165898424593512 GO:0005542 folic acid binding 6/1939 13/18639 0.461538461538462 4.43662474709406 0.00113019091089991 0.0188096058742629 GO:0016829 lyase activity 35/1939 200/18639 0.175 1.6822202166065 0.00146646743569915 0.0240624586280212 GO:0097718 disordered domain specific binding 9/1939 28/18639 0.321428571428571 3.08979223458336 0.00153858866416885 0.0248952193577322 GO:0000217 DNA secondary structure binding 11/1939 39/18639 0.282051282051282 2.7112706787797 0.0015966236351299 0.0254803634921416 GO:0030544 Hsp70 protein binding 13/1939 51/18639 0.254901960784314 2.45029275248005 0.00173107468963682 0.0272527299111742 GO:0001094 TFIID-class transcription factor complex binding 5/1939 10/18639 0.5 4.80634347601857 0.00194915910516359 0.029490524123579 GO:0005345 purine nucleobase transmembrane transporter activity 5/1939 10/18639 0.5 4.80634347601857 0.00194915910516359 0.029490524123579 GO:0047429 nucleoside triphosphate diphosphatase activity 5/1939 10/18639 0.5 4.80634347601857 0.00194915910516359 0.029490524123579 GO:0042625 ATPase-coupled ion transmembrane transporter activity 8/1939 24/18639 0.333333333333333 3.20422898401238 0.00215554757059341 0.0313901614967665 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 8/1939 24/18639 0.333333333333333 3.20422898401238 0.00215554757059341 0.0313901614967665 GO:0046961 proton-transporting ATPase activity, rotational mechanism 8/1939 24/18639 0.333333333333333 3.20422898401238 0.00215554757059341 0.0313901614967665 GO:0016887 ATP hydrolysis activity 62/1939 417/18639 0.148681055155875 1.429224438912 0.00249306518229025 0.0358570486094832 GO:0000774 adenyl-nucleotide exchange factor activity 6/1939 15/18639 0.4 3.84507478081485 0.00274467884770446 0.0385247091274181 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 6/1939 15/18639 0.4 3.84507478081485 0.00274467884770446 0.0385247091274181 GO:0001848 complement binding 8/1939 25/18639 0.32 3.07605982465188 0.00288436644880409 0.0400034156292472 GO:0042288 MHC class I protein binding 7/1939 20/18639 0.35 3.364440433213 0.00297729812346727 0.040806497809875 GO:0033218 amide binding 40/1939 247/18639 0.161943319838057 1.55671043757686 0.00311214462668841 0.0421587033731628 GO:0001851 complement component C3b binding 5/1939 11/18639 0.454545454545455 4.36940316001688 0.00326865664514066 0.0427863482200996 GO:0015205 nucleobase transmembrane transporter activity 5/1939 11/18639 0.454545454545455 4.36940316001688 0.00326865664514066 0.0427863482200996 GO:0042608 T cell receptor binding 5/1939 11/18639 0.454545454545455 4.36940316001688 0.00326865664514066 0.0427863482200996 GO:0003678 DNA helicase activity 16/1939 74/18639 0.216216216216216 2.07841880044046 0.00342727382609318 0.0443641556377618 GO:0060590 ATPase regulator activity 12/1939 49/18639 0.244897959183673 2.35412741682542 0.00368017336216868 0.0471143073288627 GO:0140097 catalytic activity, acting on DNA 51/1939 336/18639 0.151785714285714 1.45906855521992 0.00376609026180247 0.0476901647282596 GO:0001846 opsonin binding 7/1939 21/18639 0.333333333333333 3.20422898401238 0.00406975208853977 0.0509813030446111 GO:0042162 telomeric DNA binding 10/1939 38/18639 0.263157894736842 2.5296544610624 0.00447606492465988 0.0551633702233588 GO:0019205 nucleobase-containing compound kinase activity 11/1939 44/18639 0.25 2.40317173800928 0.00449830057615373 0.0551633702233588 GO:0004364 glutathione transferase activity 8/1939 27/18639 0.296296296296296 2.84820354134434 0.0049042922031661 0.0595156293405052 GO:0051539 4 iron, 4 sulfur cluster binding 11/1939 45/18639 0.244444444444444 2.34976792160908 0.0054051097043611 0.0640217780872868 GO:0008649 rRNA methyltransferase activity 7/1939 22/18639 0.318181818181818 3.05858221201181 0.00544047727952051 0.0640217780872868 GO:0140517 protein-RNA adaptor activity 7/1939 22/18639 0.318181818181818 3.05858221201181 0.00544047727952051 0.0640217780872868 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 10/1939 40/18639 0.25 2.40317173800928 0.00662589294550411 0.0771916528151229 GO:0004602 glutathione peroxidase activity 7/1939 23/18639 0.304347826086957 2.92560037670695 0.00712963267463418 0.0814315888818512 GO:0140102 catalytic activity, acting on a rRNA 7/1939 23/18639 0.304347826086957 2.92560037670695 0.00712963267463418 0.0814315888818512 GO:0019104 DNA N-glycosylase activity 5/1939 13/18639 0.384615384615385 3.69718728924505 0.00762480717481586 0.0859622838856678 GO:0070628 proteasome binding 6/1939 18/18639 0.333333333333333 3.20422898401238 0.00774767365493144 0.0859622838856678 GO:1901611 phosphatidylglycerol binding 6/1939 18/18639 0.333333333333333 3.20422898401238 0.00774767365493144 0.0859622838856678 GO:0001530 lipopolysaccharide binding 10/1939 41/18639 0.24390243902439 2.34455779317979 0.0079638636131344 0.0867093561616969 GO:0061650 ubiquitin-like protein conjugating enzyme activity 10/1939 41/18639 0.24390243902439 2.34455779317979 0.0079638636131344 0.0867093561616969 GO:0042393 histone binding 38/1939 247/18639 0.153846153846154 1.47887491569802 0.00907218776842663 0.0978620254649724 GO:0003725 double-stranded RNA binding 15/1939 75/18639 0.2 1.92253739040743 0.00954231783994048 0.101988993426887 GO:0008106 alcohol dehydrogenase (NADP+) activity 8/1939 30/18639 0.266666666666667 2.5633831872099 0.00976000947458778 0.103367373071771 GO:0019763 immunoglobulin receptor activity 5/1939 14/18639 0.357142857142857 3.4331024828704 0.0108582841149737 0.113963072017517 GO:0001046 core promoter sequence-specific DNA binding 10/1939 44/18639 0.227272727272727 2.18470158000844 0.0132396773200707 0.137716286409664 GO:0000339 RNA cap binding 6/1939 20/18639 0.3 2.88380608561114 0.0135000091300295 0.139181510057384 GO:0016874 ligase activity 27/1939 167/18639 0.161676646706587 1.55414699224552 0.0136420939220921 0.139412626484538 GO:0098505 G-rich strand telomeric DNA binding 4/1939 10/18639 0.4 3.84507478081485 0.0146524767652322 0.148435960273874 GO:0038024 cargo receptor activity 13/1939 65/18639 0.2 1.92253739040743 0.015195027893905 0.151739257362582 GO:0016835 carbon-oxygen lyase activity 15/1939 79/18639 0.189873417721519 1.82519372507034 0.015239049881049 0.151739257362582 GO:0016776 phosphotransferase activity, phosphate group as acceptor 9/1939 39/18639 0.230769230769231 2.21831237354703 0.0166185407416821 0.163632370320765 GO:0140104 molecular carrier activity 37/1939 249/18639 0.14859437751004 1.42839123383684 0.0167143794576576 0.163632370320765 GO:0000049 tRNA binding 15/1939 80/18639 0.1875 1.80237880350696 0.0170064056172031 0.16510385453368 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 6/1939 21/18639 0.285714285714286 2.74648198629632 0.0172721119466254 0.166297606758831 GO:0023026 MHC class II protein complex binding 7/1939 27/18639 0.259259259259259 2.49217809867629 0.0178737485733145 0.170679648261569 GO:0016860 intramolecular oxidoreductase activity 11/1939 53/18639 0.207547169811321 1.99508597117752 0.0188138001119602 0.178195749027916 GO:0008017 microtubule binding 40/1939 276/18639 0.144927536231884 1.39314303652712 0.0194307609166153 0.181922970588071 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 9/1939 40/18639 0.225 2.16285456420835 0.0195196320373466 0.181922970588071 GO:0043023 ribosomal large subunit binding 5/1939 16/18639 0.3125 3.0039646725116 0.0198726221834843 0.18374289558539 GO:0003727 single-stranded RNA binding 16/1939 89/18639 0.179775280898876 1.72812349699544 0.0204560575186106 0.186731114480623 GO:0061749 forked DNA-dependent helicase activity 10/1939 47/18639 0.212765957446809 2.04525254298662 0.0207802207177993 0.186731114480623 GO:1990518 single-stranded 3'-5' DNA helicase activity 10/1939 47/18639 0.212765957446809 2.04525254298662 0.0207802207177993 0.186731114480623 GO:0030332 cyclin binding 8/1939 34/18639 0.235294117647059 2.26180869459697 0.0208608227224436 0.186731114480623 GO:0004523 RNA-DNA hybrid ribonuclease activity 4/1939 11/18639 0.363636363636364 3.4955225280135 0.021157516833856 0.186731114480623 GO:0034511 U3 snoRNA binding 4/1939 11/18639 0.363636363636364 3.4955225280135 0.021157516833856 0.186731114480623 GO:0000287 magnesium ion binding 34/1939 230/18639 0.147826086956522 1.42100589725766 0.0226033718833072 0.197960381128765 GO:0042287 MHC protein binding 9/1939 41/18639 0.219512195121951 2.11010201386181 0.0227696919066563 0.197960381128765 GO:0031490 chromatin DNA binding 21/1939 128/18639 0.1640625 1.57708145306859 0.0234742788315119 0.201576736645006 GO:0009378 four-way junction helicase activity 10/1939 48/18639 0.208333333333333 2.00264311500774 0.023877759362241 0.201576736645006 GO:0036121 double-stranded DNA helicase activity 10/1939 48/18639 0.208333333333333 2.00264311500774 0.023877759362241 0.201576736645006 GO:0043138 3'-5' DNA helicase activity 10/1939 48/18639 0.208333333333333 2.00264311500774 0.023877759362241 0.201576736645006 GO:0061631 ubiquitin conjugating enzyme activity 8/1939 35/18639 0.228571428571429 2.19718558903706 0.0246486232917769 0.206587382265612 GO:0004550 nucleoside diphosphate kinase activity 5/1939 17/18639 0.294117647058824 2.82726086824622 0.0257962155087735 0.208698549081396 GO:0004659 prenyltransferase activity 5/1939 17/18639 0.294117647058824 2.82726086824622 0.0257962155087735 0.208698549081396 GO:0016018 cyclosporin A binding 5/1939 17/18639 0.294117647058824 2.82726086824622 0.0257962155087735 0.208698549081396 GO:0048038 quinone binding 5/1939 17/18639 0.294117647058824 2.82726086824622 0.0257962155087735 0.208698549081396 GO:1990226 histone methyltransferase binding 5/1939 17/18639 0.294117647058824 2.82726086824622 0.0257962155087735 0.208698549081396 GO:0016859 cis-trans isomerase activity 9/1939 42/18639 0.214285714285714 2.05986148972224 0.0263886081048265 0.212018816842227 GO:0008171 O-methyltransferase activity 6/1939 23/18639 0.260869565217391 2.50765746574882 0.0268546251604916 0.212414714524271 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 48/1939 349/18639 0.137535816618911 1.32208874985038 0.0271550073945439 0.212414714524271 GO:0016763 pentosyltransferase activity 10/1939 49/18639 0.204081632653061 1.96177284735452 0.0272945450786506 0.212414714524271 GO:0004033 aldo-keto reductase (NADPH) activity 8/1939 36/18639 0.222222222222222 2.13615265600825 0.0288919311081398 0.212414714524271 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 8/1939 36/18639 0.222222222222222 2.13615265600825 0.0288919311081398 0.212414714524271 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 8/1939 36/18639 0.222222222222222 2.13615265600825 0.0288919311081398 0.212414714524271 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 8/1939 36/18639 0.222222222222222 2.13615265600825 0.0288919311081398 0.212414714524271 GO:0004300 enoyl-CoA hydratase activity 4/1939 12/18639 0.333333333333333 3.20422898401238 0.0291728363295137 0.212414714524271 GO:0016208 AMP binding 4/1939 12/18639 0.333333333333333 3.20422898401238 0.0291728363295137 0.212414714524271 GO:0016801 hydrolase activity, acting on ether bonds 4/1939 12/18639 0.333333333333333 3.20422898401238 0.0291728363295137 0.212414714524271 GO:0016803 ether hydrolase activity 4/1939 12/18639 0.333333333333333 3.20422898401238 0.0291728363295137 0.212414714524271 GO:0043047 single-stranded telomeric DNA binding 4/1939 12/18639 0.333333333333333 3.20422898401238 0.0291728363295137 0.212414714524271 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 4/1939 12/18639 0.333333333333333 3.20422898401238 0.0291728363295137 0.212414714524271 GO:0097371 MDM2/MDM4 family protein binding 4/1939 12/18639 0.333333333333333 3.20422898401238 0.0291728363295137 0.212414714524271 GO:0097677 STAT family protein binding 4/1939 12/18639 0.333333333333333 3.20422898401238 0.0291728363295137 0.212414714524271 GO:0015631 tubulin binding 52/1939 385/18639 0.135064935064935 1.29833693897644 0.0300263323099097 0.21727128659034 GO:0000400 four-way junction DNA binding 5/1939 18/18639 0.277777777777778 2.67019082001031 0.0327379623756358 0.23121299656204 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 5/1939 18/18639 0.277777777777778 2.67019082001031 0.0327379623756358 0.23121299656204 GO:1990381 ubiquitin-specific protease binding 5/1939 18/18639 0.277777777777778 2.67019082001031 0.0327379623756358 0.23121299656204 GO:0001091 RNA polymerase II general transcription initiation factor binding 6/1939 24/18639 0.25 2.40317173800928 0.0327469050924777 0.23121299656204 GO:0016830 carbon-carbon lyase activity 10/1939 51/18639 0.196078431372549 1.88484057883081 0.035145760216938 0.246655485859836 GO:0016741 transferase activity, transferring one-carbon groups 31/1939 215/18639 0.144186046511628 1.38601532796814 0.0383094225971011 0.26554967632408 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 4/1939 13/18639 0.307692307692308 2.95774983139604 0.0387497381760461 0.26554967632408 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 4/1939 13/18639 0.307692307692308 2.95774983139604 0.0387497381760461 0.26554967632408 GO:0140666 annealing activity 4/1939 13/18639 0.307692307692308 2.95774983139604 0.0387497381760461 0.26554967632408 GO:0036002 pre-mRNA binding 11/1939 59/18639 0.186440677966102 1.7921958724137 0.0390194531605924 0.265834286152574 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 20/1939 128/18639 0.15625 1.5019823362558 0.0418952697889781 0.283767379675346 GO:0031369 translation initiation factor binding 7/1939 32/18639 0.21875 2.10277527075812 0.0429708896777312 0.287707393531936 GO:0051059 NF-kappaB binding 7/1939 32/18639 0.21875 2.10277527075812 0.0429708896777312 0.287707393531936 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 8/1939 39/18639 0.205128205128205 1.97183322093069 0.0445627655471512 0.296660696356749 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 9/1939 46/18639 0.195652173913043 1.88074309931161 0.0449054402321138 0.297243396990981 GO:0001540 amyloid-beta binding 14/1939 83/18639 0.168674698795181 1.62141707624723 0.0466297918829899 0.303473391140998 GO:0008198 ferrous iron binding 6/1939 26/18639 0.230769230769231 2.21831237354703 0.0468885926226434 0.303473391140998 GO:0019865 immunoglobulin binding 6/1939 26/18639 0.230769230769231 2.21831237354703 0.0468885926226434 0.303473391140998 GO:0070006 metalloaminopeptidase activity 6/1939 26/18639 0.230769230769231 2.21831237354703 0.0468885926226434 0.303473391140998 GO:0016836 hydro-lyase activity 11/1939 61/18639 0.180327868852459 1.7334353520067 0.0482390346972791 0.310488814488012 GO:0016530 metallochaperone activity 4/1939 14/18639 0.285714285714286 2.74648198629632 0.049906319800475 0.317709631516685 GO:0098847 sequence-specific single stranded DNA binding 4/1939 14/18639 0.285714285714286 2.74648198629632 0.049906319800475 0.317709631516685 GO:0005504 fatty acid binding 9/1939 47/18639 0.191489361702128 1.84072728868796 0.0506193080118199 0.320050997281956 GO:0004177 aminopeptidase activity 8/1939 40/18639 0.2 1.92253739040743 0.0508235489246024 0.320050997281956 GO:0004386 helicase activity 23/1939 155/18639 0.148387096774194 1.42639870901196 0.0512558813800921 0.321038181762405 GO:0019887 protein kinase regulator activity 35/1939 255/18639 0.137254901960784 1.31938840518157 0.0539311187126546 0.335987985562795 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 7/1939 34/18639 0.205882352941176 1.97908260777235 0.0573370285156345 0.355306586280395 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 5/1939 21/18639 0.238095238095238 2.28873498858027 0.0599843742718888 0.369744952522489 GO:0140299 molecular sensor activity 12/1939 71/18639 0.169014084507042 1.62467948485135 0.0615131766486537 0.37717289892464 GO:0020037 heme binding 21/1939 142/18639 0.147887323943662 1.42159454924493 0.0621673261744256 0.379188141325685 GO:0001222 transcription corepressor binding 9/1939 49/18639 0.183673469387755 1.76559556261907 0.0634270097707987 0.38485659574469 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 24/1939 167/18639 0.143712574850299 1.38146399310713 0.0641297924748171 0.387104705871305 GO:0048487 beta-tubulin binding 8/1939 42/18639 0.19047619047619 1.83098799086422 0.064974101807357 0.390179528894695 GO:0046906 tetrapyrrole binding 22/1939 152/18639 0.144736842105263 1.39130995358432 0.0693794759938658 0.414497895040275 GO:0070034 telomerase RNA binding 5/1939 22/18639 0.227272727272727 2.18470158000844 0.0712418446616237 0.423452801177508 GO:0019207 kinase regulator activity 38/1939 287/18639 0.132404181184669 1.27275994486903 0.0717015712620774 0.424021982336651 GO:0003785 actin monomer binding 6/1939 29/18639 0.206896551724138 1.9888317831801 0.0742425330958273 0.430585601005136 GO:0004540 RNA nuclease activity 18/1939 121/18639 0.148760330578512 1.4299864887328 0.0760965894079238 0.430585601005136 GO:0000062 fatty-acyl-CoA binding 4/1939 16/18639 0.25 2.40317173800928 0.0768829986676497 0.430585601005136 GO:0005159 insulin-like growth factor receptor binding 4/1939 16/18639 0.25 2.40317173800928 0.0768829986676497 0.430585601005136 GO:0097027 ubiquitin-protein transferase activator activity 4/1939 16/18639 0.25 2.40317173800928 0.0768829986676497 0.430585601005136 GO:0003680 minor groove of adenine-thymine-rich DNA binding 3/1939 10/18639 0.3 2.88380608561114 0.0772466872189472 0.430585601005136 GO:0004090 carbonyl reductase (NADPH) activity 3/1939 10/18639 0.3 2.88380608561114 0.0772466872189472 0.430585601005136 GO:0016783 sulfurtransferase activity 3/1939 10/18639 0.3 2.88380608561114 0.0772466872189472 0.430585601005136 GO:0030957 Tat protein binding 3/1939 10/18639 0.3 2.88380608561114 0.0772466872189472 0.430585601005136 GO:0032356 oxidized DNA binding 3/1939 10/18639 0.3 2.88380608561114 0.0772466872189472 0.430585601005136 GO:0033204 ribonuclease P RNA binding 3/1939 10/18639 0.3 2.88380608561114 0.0772466872189472 0.430585601005136 GO:0097177 mitochondrial ribosome binding 3/1939 10/18639 0.3 2.88380608561114 0.0772466872189472 0.430585601005136 GO:0140597 protein carrier chaperone 26/1939 188/18639 0.138297872340426 1.32941415294131 0.0807345226804892 0.447884375822714 GO:0016790 thiolester hydrolase activity 8/1939 44/18639 0.181818181818182 1.74776126400675 0.0813381843973532 0.449094714800552 GO:0030527 structural constituent of chromatin 15/1939 98/18639 0.153061224489796 1.47132963551589 0.0817577405410866 0.449281923256443 GO:0023023 MHC protein complex binding 7/1939 37/18639 0.189189189189189 1.8186164503854 0.0838526096822497 0.456855167646618 GO:0046982 protein heterodimerization activity 47/1939 369/18639 0.127371273712737 1.22438018088278 0.0839201767179196 0.456855167646618 GO:0008173 RNA methyltransferase activity 11/1939 67/18639 0.164179104477612 1.57820233540908 0.0843396421976536 0.457003177489612 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 9/1939 52/18639 0.173076923076923 1.66373428016027 0.0861789228990864 0.464807616562202 GO:0001221 transcription coregulator binding 17/1939 115/18639 0.147826086956522 1.42100589725766 0.0867973620722059 0.465985837853087 GO:0030145 manganese ion binding 11/1939 68/18639 0.161764705882353 1.55499347753542 0.0916367206501378 0.48015506843182 GO:1990841 promoter-specific chromatin binding 11/1939 68/18639 0.161764705882353 1.55499347753542 0.0916367206501378 0.48015506843182 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 4/1939 17/18639 0.235294117647059 2.26180869459697 0.0926020088703809 0.48015506843182 GO:0017110 nucleoside diphosphate phosphatase activity 4/1939 17/18639 0.235294117647059 2.26180869459697 0.0926020088703809 0.48015506843182 GO:0030169 low-density lipoprotein particle binding 4/1939 17/18639 0.235294117647059 2.26180869459697 0.0926020088703809 0.48015506843182 GO:0032977 membrane insertase activity 4/1939 17/18639 0.235294117647059 2.26180869459697 0.0926020088703809 0.48015506843182 GO:1901567 fatty acid derivative binding 4/1939 17/18639 0.235294117647059 2.26180869459697 0.0926020088703809 0.48015506843182 GO:0098631 cell adhesion mediator activity 12/1939 76/18639 0.157894736842105 1.51779267663744 0.0929502350670545 0.48015506843182 GO:0004857 enzyme inhibitor activity 52/1939 416/18639 0.125 1.20158586900464 0.0931459617730398 0.48015506843182 GO:0051117 ATPase binding 13/1939 84/18639 0.154761904761905 1.48767774257718 0.093619706815979 0.480403416817435 GO:0043531 ADP binding 7/1939 38/18639 0.184210526315789 1.77075812274368 0.0940188661239272 0.480403416817435 GO:1901505 carbohydrate derivative transmembrane transporter activity 9/1939 53/18639 0.169811320754717 1.63234306732706 0.0947157312180376 0.481850772353772 GO:0004518 nuclease activity 28/1939 209/18639 0.133971291866029 1.28782408926813 0.0977569001371423 0.483106949038228 GO:0008199 ferric iron binding 3/1939 11/18639 0.272727272727273 2.62164189601013 0.0982801261133562 0.483106949038228 GO:0008526 phosphatidylinositol transfer activity 3/1939 11/18639 0.272727272727273 2.62164189601013 0.0982801261133562 0.483106949038228 GO:0010854 adenylate cyclase regulator activity 3/1939 11/18639 0.272727272727273 2.62164189601013 0.0982801261133562 0.483106949038228 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 3/1939 11/18639 0.272727272727273 2.62164189601013 0.0982801261133562 0.483106949038228 GO:0015217 ADP transmembrane transporter activity 3/1939 11/18639 0.272727272727273 2.62164189601013 0.0982801261133562 0.483106949038228 GO:0019206 nucleoside kinase activity 3/1939 11/18639 0.272727272727273 2.62164189601013 0.0982801261133562 0.483106949038228 GO:0050786 RAGE receptor binding 3/1939 11/18639 0.272727272727273 2.62164189601013 0.0982801261133562 0.483106949038228 GO:0002039 p53 binding 11/1939 69/18639 0.159420289855072 1.53245734017983 0.099303734676975 0.486087608817966 GO:0008094 ATP-dependent activity, acting on DNA 28/1939 210/18639 0.133333333333333 1.28169159360495 0.102129837183746 0.497829541083952 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 9/1939 54/18639 0.166666666666667 1.60211449200619 0.103726122798444 0.50350388775078 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 7/1939 39/18639 0.179487179487179 1.72535406831436 0.104837388125097 0.506786544256174 GO:0003689 DNA clamp loader activity 22/1939 160/18639 0.1375 1.32174445590511 0.106228945266074 0.511391410061884 GO:0004519 endonuclease activity 18/1939 127/18639 0.141732283464567 1.36242807194227 0.10854986410898 0.513283196024505 GO:0071813 lipoprotein particle binding 6/1939 32/18639 0.1875 1.80237880350696 0.108969733501355 0.513283196024505 GO:0071814 protein-lipid complex binding 6/1939 32/18639 0.1875 1.80237880350696 0.108969733501355 0.513283196024505 GO:0000900 mRNA regulatory element binding translation repressor activity 4/1939 18/18639 0.222222222222222 2.13615265600825 0.109706022154594 0.513283196024505 GO:0016854 racemase and epimerase activity 4/1939 18/18639 0.222222222222222 2.13615265600825 0.109706022154594 0.513283196024505 GO:0031690 adrenergic receptor binding 4/1939 18/18639 0.222222222222222 2.13615265600825 0.109706022154594 0.513283196024505 GO:0035615 clathrin adaptor activity 4/1939 18/18639 0.222222222222222 2.13615265600825 0.109706022154594 0.513283196024505 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 5/1939 25/18639 0.2 1.92253739040743 0.111328966374552 0.51873488977019 GO:0002020 protease binding 19/1939 136/18639 0.139705882352941 1.34294891241695 0.112620030350545 0.51873488977019 GO:0016779 nucleotidyltransferase activity 19/1939 136/18639 0.139705882352941 1.34294891241695 0.112620030350545 0.51873488977019 GO:0005525 GTP binding 47/1939 378/18639 0.124338624338624 1.19522827181414 0.112652297950093 0.51873488977019 GO:0015036 disulfide oxidoreductase activity 7/1939 40/18639 0.175 1.6822202166065 0.116294869167626 0.527361981796463 GO:0030331 nuclear estrogen receptor binding 7/1939 40/18639 0.175 1.6822202166065 0.116294869167626 0.527361981796463 GO:0016922 nuclear receptor binding 19/1939 137/18639 0.138686131386861 1.33314636561099 0.118676515991619 0.527361981796463 GO:0016879 ligase activity, forming carbon-nitrogen bonds 8/1939 48/18639 0.166666666666667 1.60211449200619 0.120685084321795 0.527361981796463 GO:0038187 pattern recognition receptor activity 8/1939 48/18639 0.166666666666667 1.60211449200619 0.120685084321795 0.527361981796463 GO:0000340 RNA 7-methylguanosine cap binding 3/1939 12/18639 0.25 2.40317173800928 0.121315889374637 0.527361981796463 GO:0003720 telomerase activity 3/1939 12/18639 0.25 2.40317173800928 0.121315889374637 0.527361981796463 GO:0003995 acyl-CoA dehydrogenase activity 3/1939 12/18639 0.25 2.40317173800928 0.121315889374637 0.527361981796463 GO:0004032 aldose reductase (NADPH) activity 3/1939 12/18639 0.25 2.40317173800928 0.121315889374637 0.527361981796463 GO:0004526 ribonuclease P activity 3/1939 12/18639 0.25 2.40317173800928 0.121315889374637 0.527361981796463 GO:0004875 complement receptor activity 3/1939 12/18639 0.25 2.40317173800928 0.121315889374637 0.527361981796463 GO:0016423 tRNA (guanine) methyltransferase activity 3/1939 12/18639 0.25 2.40317173800928 0.121315889374637 0.527361981796463 GO:0016840 carbon-nitrogen lyase activity 3/1939 12/18639 0.25 2.40317173800928 0.121315889374637 0.527361981796463 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 3/1939 12/18639 0.25 2.40317173800928 0.121315889374637 0.527361981796463 GO:1990817 poly(A) RNA polymerase activity 3/1939 12/18639 0.25 2.40317173800928 0.121315889374637 0.527361981796463 GO:0004529 DNA exonuclease activity 5/1939 26/18639 0.192307692307692 1.84859364462253 0.126671912505959 0.538875794566703 GO:0050750 low-density lipoprotein particle receptor binding 5/1939 26/18639 0.192307692307692 1.84859364462253 0.126671912505959 0.538875794566703 GO:0120014 phospholipid transfer activity 5/1939 26/18639 0.192307692307692 1.84859364462253 0.126671912505959 0.538875794566703 GO:0005346 purine ribonucleotide transmembrane transporter activity 4/1939 19/18639 0.210526315789474 2.02372356884992 0.128098003186356 0.538875794566703 GO:0050145 nucleoside monophosphate kinase activity 4/1939 19/18639 0.210526315789474 2.02372356884992 0.128098003186356 0.538875794566703 GO:0070003 threonine-type peptidase activity 4/1939 19/18639 0.210526315789474 2.02372356884992 0.128098003186356 0.538875794566703 GO:0120227 acyl-CoA binding 4/1939 19/18639 0.210526315789474 2.02372356884992 0.128098003186356 0.538875794566703 GO:0019001 guanyl nucleotide binding 49/1939 400/18639 0.1225 1.17755415162455 0.128127549437748 0.538875794566703 GO:0032561 guanyl ribonucleotide binding 49/1939 400/18639 0.1225 1.17755415162455 0.128127549437748 0.538875794566703 GO:0015932 nucleobase-containing compound transmembrane transporter activity 9/1939 57/18639 0.157894736842105 1.51779267663744 0.133538271701592 0.555972118994391 GO:0004521 RNA endonuclease activity 11/1939 73/18639 0.150684931506849 1.4484870749645 0.13362420027333 0.555972118994391 GO:0043539 protein serine/threonine kinase activator activity 11/1939 73/18639 0.150684931506849 1.4484870749645 0.13362420027333 0.555972118994391 GO:0016831 carboxy-lyase activity 6/1939 34/18639 0.176470588235294 1.69635652094773 0.13599297512581 0.563814291891702 GO:0061134 peptidase regulator activity 29/1939 226/18639 0.128318584070796 1.23348637880122 0.137872324762382 0.569578930312675 GO:0001671 ATPase activator activity 5/1939 27/18639 0.185185185185185 1.78012721334021 0.142920404424288 0.581196486939107 GO:0005044 scavenger receptor activity 5/1939 27/18639 0.185185185185185 1.78012721334021 0.142920404424288 0.581196486939107 GO:0008408 3'-5' exonuclease activity 9/1939 58/18639 0.155172413793103 1.49162383738507 0.144372101963106 0.581196486939107 GO:0003964 RNA-directed DNA polymerase activity 3/1939 13/18639 0.230769230769231 2.21831237354703 0.146085734734214 0.581196486939107 GO:0005172 vascular endothelial growth factor receptor binding 3/1939 13/18639 0.230769230769231 2.21831237354703 0.146085734734214 0.581196486939107 GO:0005338 nucleotide-sugar transmembrane transporter activity 3/1939 13/18639 0.230769230769231 2.21831237354703 0.146085734734214 0.581196486939107 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 3/1939 13/18639 0.230769230769231 2.21831237354703 0.146085734734214 0.581196486939107 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 3/1939 13/18639 0.230769230769231 2.21831237354703 0.146085734734214 0.581196486939107 GO:0061459 L-arginine transmembrane transporter activity 3/1939 13/18639 0.230769230769231 2.21831237354703 0.146085734734214 0.581196486939107 GO:0140098 catalytic activity, acting on RNA 47/1939 387/18639 0.121447028423773 1.16743226549288 0.147157572321513 0.581196486939107 GO:0001614 purinergic nucleotide receptor activity 4/1939 20/18639 0.2 1.92253739040743 0.147668806981953 0.581196486939107 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 4/1939 20/18639 0.2 1.92253739040743 0.147668806981953 0.581196486939107 GO:0016502 nucleotide receptor activity 4/1939 20/18639 0.2 1.92253739040743 0.147668806981953 0.581196486939107 GO:0016505 peptidase activator activity involved in apoptotic process 4/1939 20/18639 0.2 1.92253739040743 0.147668806981953 0.581196486939107 GO:0005154 epidermal growth factor receptor binding 6/1939 35/18639 0.171428571428571 1.64788919177779 0.150575839671508 0.588660581266132 GO:0034061 DNA polymerase activity 6/1939 35/18639 0.171428571428571 1.64788919177779 0.150575839671508 0.588660581266132 GO:0008200 ion channel inhibitor activity 7/1939 43/18639 0.162790697674419 1.56485601544791 0.154310539129312 0.598346922223852 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 7/1939 43/18639 0.162790697674419 1.56485601544791 0.154310539129312 0.598346922223852 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 10/1939 67/18639 0.149253731343284 1.43472939582644 0.154594355012343 0.598346922223852 GO:0016866 intramolecular transferase activity 5/1939 28/18639 0.178571428571429 1.7165512414352 0.160012681033524 0.614332972669148 GO:0019789 SUMO transferase activity 5/1939 28/18639 0.178571428571429 1.7165512414352 0.160012681033524 0.614332972669148 GO:0004527 exonuclease activity 12/1939 84/18639 0.142857142857143 1.37324099314816 0.160306629778044 0.614332972669148 GO:0008168 methyltransferase activity 26/1939 204/18639 0.127450980392157 1.22514637624003 0.16144801002197 0.616678464510148 GO:0019903 protein phosphatase binding 19/1939 144/18639 0.131944444444444 1.2683406395049 0.166384194636637 0.625385371229787 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 9/1939 60/18639 0.15 1.44190304280557 0.167309118361894 0.625385371229787 GO:0042277 peptide binding 31/1939 249/18639 0.124497991967871 1.19676022294438 0.167631690442045 0.625385371229787 GO:0016248 channel inhibitor activity 7/1939 44/18639 0.159090909090909 1.52929110600591 0.168116119754278 0.625385371229787 GO:0005123 death receptor binding 4/1939 21/18639 0.19047619047619 1.83098799086422 0.168300438207851 0.625385371229787 GO:0051428 peptide hormone receptor binding 4/1939 21/18639 0.19047619047619 1.83098799086422 0.168300438207851 0.625385371229787 GO:0140312 cargo adaptor activity 4/1939 21/18639 0.19047619047619 1.83098799086422 0.168300438207851 0.625385371229787 GO:0005080 protein kinase C binding 8/1939 52/18639 0.153846153846154 1.47887491569802 0.168350676510868 0.625385371229787 GO:0044325 transmembrane transporter binding 18/1939 136/18639 0.132352941176471 1.2722673907108 0.170955873045381 0.625385371229787 GO:0005347 ATP transmembrane transporter activity 3/1939 14/18639 0.214285714285714 2.05986148972224 0.172316484261598 0.625385371229787 GO:0008474 palmitoyl-(protein) hydrolase activity 3/1939 14/18639 0.214285714285714 2.05986148972224 0.172316484261598 0.625385371229787 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 3/1939 14/18639 0.214285714285714 2.05986148972224 0.172316484261598 0.625385371229787 GO:0030983 mismatched DNA binding 3/1939 14/18639 0.214285714285714 2.05986148972224 0.172316484261598 0.625385371229787 GO:0098599 palmitoyl hydrolase activity 3/1939 14/18639 0.214285714285714 2.05986148972224 0.172316484261598 0.625385371229787 GO:1901612 cardiolipin binding 3/1939 14/18639 0.214285714285714 2.05986148972224 0.172316484261598 0.625385371229787 GO:1990825 sequence-specific mRNA binding 3/1939 14/18639 0.214285714285714 2.05986148972224 0.172316484261598 0.625385371229787 GO:0004864 protein phosphatase inhibitor activity 8/1939 53/18639 0.150943396226415 1.45097161540183 0.181441333451815 0.653285948604028 GO:0140296 general transcription initiation factor binding 8/1939 53/18639 0.150943396226415 1.45097161540183 0.181441333451815 0.653285948604028 GO:0022829 wide pore channel activity 6/1939 37/18639 0.162162162162162 1.55881410033035 0.181686392573137 0.653285948604028 GO:0141110 transporter inhibitor activity 7/1939 45/18639 0.155555555555556 1.49530685920578 0.182440662511905 0.653979605619598 GO:0034062 5'-3' RNA polymerase activity 4/1939 22/18639 0.181818181818182 1.74776126400675 0.189869014551457 0.676444654288829 GO:0097747 RNA polymerase activity 4/1939 22/18639 0.181818181818182 1.74776126400675 0.189869014551457 0.676444654288829 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 8/1939 54/18639 0.148148148148148 1.42410177067217 0.194957022261098 0.687298088428531 GO:0050661 NADP binding 8/1939 54/18639 0.148148148148148 1.42410177067217 0.194957022261098 0.687298088428531 GO:0008187 poly-pyrimidine tract binding 5/1939 30/18639 0.166666666666667 1.60211449200619 0.196455161756825 0.687298088428531 GO:0016769 transferase activity, transferring nitrogenous groups 5/1939 30/18639 0.166666666666667 1.60211449200619 0.196455161756825 0.687298088428531 GO:0031210 phosphatidylcholine binding 5/1939 30/18639 0.166666666666667 1.60211449200619 0.196455161756825 0.687298088428531 GO:0035925 mRNA 3'-UTR AU-rich region binding 5/1939 30/18639 0.166666666666667 1.60211449200619 0.196455161756825 0.687298088428531 GO:0015556 C4-dicarboxylate transmembrane transporter activity 3/1939 15/18639 0.2 1.92253739040743 0.199738004190345 0.692543972862357 GO:0050700 CARD domain binding 3/1939 15/18639 0.2 1.92253739040743 0.199738004190345 0.692543972862357 GO:0050780 dopamine receptor binding 3/1939 15/18639 0.2 1.92253739040743 0.199738004190345 0.692543972862357 GO:0098632 cell-cell adhesion mediator activity 8/1939 55/18639 0.145454545454545 1.3982090112054 0.208872242379368 0.722065763715024 GO:0000295 adenine nucleotide transmembrane transporter activity 4/1939 23/18639 0.173913043478261 1.67177164383254 0.21224741175042 0.72725951379188 GO:0043274 phospholipase binding 4/1939 23/18639 0.173913043478261 1.67177164383254 0.21224741175042 0.72725951379188 GO:0070577 lysine-acetylated histone binding 4/1939 23/18639 0.173913043478261 1.67177164383254 0.21224741175042 0.72725951379188 GO:0005164 tumor necrosis factor receptor binding 5/1939 31/18639 0.161290322580645 1.55043337936083 0.21565904857844 0.732486272868461 GO:0008327 methyl-CpG binding 5/1939 31/18639 0.161290322580645 1.55043337936083 0.21565904857844 0.732486272868461 GO:0070325 lipoprotein particle receptor binding 5/1939 31/18639 0.161290322580645 1.55043337936083 0.21565904857844 0.732486272868461 GO:0004536 DNA nuclease activity 9/1939 64/18639 0.140625 1.35178410263022 0.21779052452634 0.737533065270422 GO:0001618 virus receptor activity 11/1939 81/18639 0.135802469135802 1.30542662311615 0.218411079414846 0.737533065270422 GO:0019212 phosphatase inhibitor activity 8/1939 56/18639 0.142857142857143 1.37324099314816 0.223160024470846 0.751391411874379 GO:0031406 carboxylic acid binding 23/1939 187/18639 0.122994652406417 1.18230909035751 0.227219130059091 0.757048064379706 GO:0008142 oxysterol binding 3/1939 16/18639 0.1875 1.80237880350696 0.228089159310967 0.757048064379706 GO:0008296 3'-5'-DNA exonuclease activity 3/1939 16/18639 0.1875 1.80237880350696 0.228089159310967 0.757048064379706 GO:0016722 oxidoreductase activity, acting on metal ions 3/1939 16/18639 0.1875 1.80237880350696 0.228089159310967 0.757048064379706 GO:0055102 lipase inhibitor activity 3/1939 16/18639 0.1875 1.80237880350696 0.228089159310967 0.757048064379706 GO:0140272 exogenous protein binding 11/1939 82/18639 0.134146341463415 1.28950678624888 0.230317873536813 0.762273643949962 GO:0050997 quaternary ammonium group binding 6/1939 40/18639 0.15 1.44190304280557 0.232518865111653 0.765735570769552 GO:0072341 modified amino acid binding 12/1939 91/18639 0.131868131868132 1.2676070705983 0.234766919958927 0.765735570769552 GO:0005540 hyaluronic acid binding 4/1939 24/18639 0.166666666666667 1.60211449200619 0.2353075831206 0.765735570769552 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 4/1939 24/18639 0.166666666666667 1.60211449200619 0.2353075831206 0.765735570769552 GO:0140033 acetylation-dependent protein binding 4/1939 24/18639 0.166666666666667 1.60211449200619 0.2353075831206 0.765735570769552 GO:0140612 DNA damage sensor activity 4/1939 24/18639 0.166666666666667 1.60211449200619 0.2353075831206 0.765735570769552 GO:0048029 monosaccharide binding 10/1939 74/18639 0.135135135135135 1.29901175027529 0.237534757753876 0.770830063463134 GO:0043177 organic acid binding 23/1939 189/18639 0.121693121693122 1.16979788305214 0.24306083560695 0.786571870783603 GO:0052689 carboxylic ester hydrolase activity 12/1939 92/18639 0.130434782608696 1.25382873287441 0.246382469988962 0.795112403149976 GO:0042169 SH2 domain binding 6/1939 41/18639 0.146341463414634 1.40673467590787 0.250372259224115 0.79642751163528 GO:0019902 phosphatase binding 23/1939 190/18639 0.121052631578947 1.16364105208871 0.251153731390466 0.79642751163528 GO:0140416 transcription regulator inhibitor activity 5/1939 33/18639 0.151515151515152 1.45646772000563 0.255649153289156 0.79642751163528 GO:0004029 aldehyde dehydrogenase (NAD+) activity 3/1939 17/18639 0.176470588235294 1.69635652094773 0.257122120119664 0.79642751163528 GO:0004549 tRNA-specific ribonuclease activity 3/1939 17/18639 0.176470588235294 1.69635652094773 0.257122120119664 0.79642751163528 GO:0008429 phosphatidylethanolamine binding 3/1939 17/18639 0.176470588235294 1.69635652094773 0.257122120119664 0.79642751163528 GO:0015278 intracellularly gated calcium channel activity 3/1939 17/18639 0.176470588235294 1.69635652094773 0.257122120119664 0.79642751163528 GO:0070403 NAD+ binding 3/1939 17/18639 0.176470588235294 1.69635652094773 0.257122120119664 0.79642751163528 GO:0140713 histone chaperone activity 20/1939 164/18639 0.121951219512195 1.17227889658989 0.258857735936373 0.79642751163528 GO:0008483 transaminase activity 4/1939 25/18639 0.16 1.53802991232594 0.258922557738895 0.79642751163528 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 4/1939 25/18639 0.16 1.53802991232594 0.258922557738895 0.79642751163528 GO:0017025 TBP-class protein binding 4/1939 25/18639 0.16 1.53802991232594 0.258922557738895 0.79642751163528 GO:0015605 organophosphate ester transmembrane transporter activity 7/1939 50/18639 0.14 1.3457761732852 0.260643112928398 0.79642751163528 GO:0032813 tumor necrosis factor receptor superfamily binding 7/1939 50/18639 0.14 1.3457761732852 0.260643112928398 0.79642751163528 GO:0015459 potassium channel regulator activity 8/1939 59/18639 0.135593220338983 1.30341517993724 0.267971568501421 0.79642751163528 GO:0031593 polyubiquitin modification-dependent protein binding 8/1939 59/18639 0.135593220338983 1.30341517993724 0.267971568501421 0.79642751163528 GO:0004520 DNA endonuclease activity 6/1939 42/18639 0.142857142857143 1.37324099314816 0.268591959263922 0.79642751163528 GO:0051879 Hsp90 protein binding 6/1939 42/18639 0.142857142857143 1.37324099314816 0.268591959263922 0.79642751163528 GO:0016410 N-acyltransferase activity 12/1939 94/18639 0.127659574468085 1.22715152579197 0.270219711387117 0.79642751163528 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 16/1939 130/18639 0.123076923076923 1.18309993255842 0.27593702356569 0.79642751163528 GO:0015035 protein-disulfide reductase activity 5/1939 34/18639 0.147058823529412 1.41363043412311 0.276279528834561 0.79642751163528 GO:0061135 endopeptidase regulator activity 22/1939 184/18639 0.119565217391304 1.14934300513487 0.276460584869865 0.79642751163528 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0004955 prostaglandin receptor activity 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0005337 nucleoside transmembrane transporter activity 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0005528 FK506 binding 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0015643 toxic substance binding 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0016868 intramolecular phosphotransferase activity 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0031720 haptoglobin binding 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0032395 MHC class II receptor activity 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0043295 glutathione binding 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0043422 protein kinase B binding 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0050815 phosphoserine residue binding 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0070513 death domain binding 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0140940 histone H2A methyltransferase activity 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0141109 transporter activator activity 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:1990259 histone H2AQ104 methyltransferase activity 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:1990757 ubiquitin ligase activator activity 2/1939 10/18639 0.2 1.92253739040743 0.279534727055782 0.79642751163528 GO:0050660 flavin adenine dinucleotide binding 11/1939 86/18639 0.127906976744186 1.22952972642335 0.280233205280201 0.79642751163528 GO:0015216 purine nucleotide transmembrane transporter activity 4/1939 26/18639 0.153846153846154 1.47887491569802 0.282968129599429 0.79642751163528 GO:0050681 nuclear androgen receptor binding 4/1939 26/18639 0.153846153846154 1.47887491569802 0.282968129599429 0.79642751163528 GO:0001098 basal transcription machinery binding 8/1939 60/18639 0.133333333333333 1.28169159360495 0.283458099292118 0.79642751163528 GO:0001099 basal RNA polymerase II transcription machinery binding 8/1939 60/18639 0.133333333333333 1.28169159360495 0.283458099292118 0.79642751163528 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 8/1939 60/18639 0.133333333333333 1.28169159360495 0.283458099292118 0.79642751163528 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 3/1939 18/18639 0.166666666666667 1.60211449200619 0.286605339712678 0.79642751163528 GO:0008409 5'-3' exonuclease activity 3/1939 18/18639 0.166666666666667 1.60211449200619 0.286605339712678 0.79642751163528 GO:0008525 phosphatidylcholine transporter activity 3/1939 18/18639 0.166666666666667 1.60211449200619 0.286605339712678 0.79642751163528 GO:0098641 cadherin binding involved in cell-cell adhesion 3/1939 18/18639 0.166666666666667 1.60211449200619 0.286605339712678 0.79642751163528 GO:0004712 protein serine/threonine/tyrosine kinase activity 6/1939 43/18639 0.13953488372093 1.3413051560982 0.287124081447912 0.79642751163528 GO:0048156 tau protein binding 6/1939 43/18639 0.13953488372093 1.3413051560982 0.287124081447912 0.79642751163528 GO:0019842 vitamin binding 18/1939 150/18639 0.12 1.15352243424446 0.296434563054423 0.8202999191411 GO:0000510 H3-H4 histone complex chaperone activity 18/1939 151/18639 0.119205298013245 1.14588321282562 0.306403417844835 0.837404306441357 GO:0140584 chromatin extrusion motor activity 18/1939 151/18639 0.119205298013245 1.14588321282562 0.306403417844835 0.837404306441357 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 18/1939 151/18639 0.119205298013245 1.14588321282562 0.306403417844835 0.837404306441357 GO:0140849 ATP-dependent H2AZ histone chaperone activity 18/1939 151/18639 0.119205298013245 1.14588321282562 0.306403417844835 0.837404306441357 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 3/1939 19/18639 0.157894736842105 1.51779267663744 0.316325465311364 0.837404306441357 GO:0097001 ceramide binding 3/1939 19/18639 0.157894736842105 1.51779267663744 0.316325465311364 0.837404306441357 GO:0015616 DNA translocase activity 18/1939 152/18639 0.118421052631579 1.13834450747808 0.316469752366874 0.837404306441357 GO:0140674 ATP-dependent histone chaperone activity 18/1939 152/18639 0.118421052631579 1.13834450747808 0.316469752366874 0.837404306441357 GO:0044390 ubiquitin-like protein conjugating enzyme binding 5/1939 36/18639 0.138888888888889 1.33509541000516 0.318425093515718 0.837404306441357 GO:0048306 calcium-dependent protein binding 10/1939 80/18639 0.125 1.20158586900464 0.318818802071614 0.837404306441357 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 2/1939 11/18639 0.181818181818182 1.74776126400675 0.319813527265209 0.837404306441357 GO:0004954 prostanoid receptor activity 2/1939 11/18639 0.181818181818182 1.74776126400675 0.319813527265209 0.837404306441357 GO:0015173 aromatic amino acid transmembrane transporter activity 2/1939 11/18639 0.181818181818182 1.74776126400675 0.319813527265209 0.837404306441357 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/1939 11/18639 0.181818181818182 1.74776126400675 0.319813527265209 0.837404306441357 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 2/1939 11/18639 0.181818181818182 1.74776126400675 0.319813527265209 0.837404306441357 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/1939 11/18639 0.181818181818182 1.74776126400675 0.319813527265209 0.837404306441357 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/1939 11/18639 0.181818181818182 1.74776126400675 0.319813527265209 0.837404306441357 GO:0032404 mismatch repair complex binding 2/1939 11/18639 0.181818181818182 1.74776126400675 0.319813527265209 0.837404306441357 GO:0034713 type I transforming growth factor beta receptor binding 2/1939 11/18639 0.181818181818182 1.74776126400675 0.319813527265209 0.837404306441357 GO:0045294 alpha-catenin binding 2/1939 11/18639 0.181818181818182 1.74776126400675 0.319813527265209 0.837404306441357 GO:0140031 phosphorylation-dependent protein binding 2/1939 11/18639 0.181818181818182 1.74776126400675 0.319813527265209 0.837404306441357 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/1939 11/18639 0.181818181818182 1.74776126400675 0.319813527265209 0.837404306441357 GO:1900750 oligopeptide binding 2/1939 11/18639 0.181818181818182 1.74776126400675 0.319813527265209 0.837404306441357 GO:0019888 protein phosphatase regulator activity 13/1939 107/18639 0.121495327102804 1.1678965455746 0.319866881001205 0.837404306441357 GO:0042605 peptide antigen binding 6/1939 45/18639 0.133333333333333 1.28169159360495 0.324910835276989 0.845096418494121 GO:0061775 cohesin loader activity 18/1939 153/18639 0.117647058823529 1.13090434729849 0.3266259792447 0.845096418494121 GO:0140463 chromatin-protein adaptor activity 7/1939 54/18639 0.12962962962963 1.24608904933815 0.328815389703152 0.845096418494121 GO:0005507 copper ion binding 8/1939 63/18639 0.126984126984127 1.22065866057614 0.331131727688796 0.845096418494121 GO:1990782 protein tyrosine kinase binding 14/1939 117/18639 0.11965811965812 1.1502360455429 0.331238900225173 0.845096418494121 GO:0046625 sphingolipid binding 4/1939 28/18639 0.142857142857143 1.37324099314816 0.331876184830732 0.845096418494121 GO:0033192 calmodulin-dependent protein phosphatase activity 10/1939 81/18639 0.123456790123457 1.18675147556014 0.332960734840173 0.845096418494121 GO:0140791 histone H2AXS140 phosphatase activity 10/1939 81/18639 0.123456790123457 1.18675147556014 0.332960734840173 0.845096418494121 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 10/1939 81/18639 0.123456790123457 1.18675147556014 0.332960734840173 0.845096418494121 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 10/1939 81/18639 0.123456790123457 1.18675147556014 0.332960734840173 0.845096418494121 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 10/1939 81/18639 0.123456790123457 1.18675147556014 0.332960734840173 0.845096418494121 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 10/1939 81/18639 0.123456790123457 1.18675147556014 0.332960734840173 0.845096418494121 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 10/1939 81/18639 0.123456790123457 1.18675147556014 0.332960734840173 0.845096418494121 GO:1990439 MAP kinase serine/threonine phosphatase activity 10/1939 81/18639 0.123456790123457 1.18675147556014 0.332960734840173 0.845096418494121 GO:0140030 modification-dependent protein binding 20/1939 173/18639 0.115606936416185 1.11129328925285 0.343231207718954 0.866182957785446 GO:0010851 cyclase regulator activity 3/1939 20/18639 0.15 1.44190304280557 0.346088405016553 0.866182957785446 GO:0016004 phospholipase activator activity 3/1939 20/18639 0.15 1.44190304280557 0.346088405016553 0.866182957785446 GO:0030742 GTP-dependent protein binding 3/1939 20/18639 0.15 1.44190304280557 0.346088405016553 0.866182957785446 GO:0061608 nuclear import signal receptor activity 3/1939 20/18639 0.15 1.44190304280557 0.346088405016553 0.866182957785446 GO:0140664 ATP-dependent DNA damage sensor activity 3/1939 20/18639 0.15 1.44190304280557 0.346088405016553 0.866182957785446 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 10/1939 82/18639 0.121951219512195 1.17227889658989 0.347216687798973 0.866182957785446 GO:0033549 MAP kinase phosphatase activity 10/1939 82/18639 0.121951219512195 1.17227889658989 0.347216687798973 0.866182957785446 GO:0099604 ligand-gated calcium channel activity 4/1939 29/18639 0.137931034482759 1.3258878554534 0.356515340507029 0.872568143525984 GO:0140375 immune receptor activity 18/1939 156/18639 0.115384615384615 1.10915618677352 0.357556740470092 0.872568143525984 GO:0004859 phospholipase inhibitor activity 2/1939 12/18639 0.166666666666667 1.60211449200619 0.359513054843324 0.872568143525984 GO:0005527 macrolide binding 2/1939 12/18639 0.166666666666667 1.60211449200619 0.359513054843324 0.872568143525984 GO:0008179 adenylate cyclase binding 2/1939 12/18639 0.166666666666667 1.60211449200619 0.359513054843324 0.872568143525984 GO:0008603 cAMP-dependent protein kinase regulator activity 2/1939 12/18639 0.166666666666667 1.60211449200619 0.359513054843324 0.872568143525984 GO:0010853 cyclase activator activity 2/1939 12/18639 0.166666666666667 1.60211449200619 0.359513054843324 0.872568143525984 GO:0015132 prostaglandin transmembrane transporter activity 2/1939 12/18639 0.166666666666667 1.60211449200619 0.359513054843324 0.872568143525984 GO:0034452 dynactin binding 2/1939 12/18639 0.166666666666667 1.60211449200619 0.359513054843324 0.872568143525984 GO:0036009 protein-glutamine N-methyltransferase activity 2/1939 12/18639 0.166666666666667 1.60211449200619 0.359513054843324 0.872568143525984 GO:0042301 phosphate ion binding 2/1939 12/18639 0.166666666666667 1.60211449200619 0.359513054843324 0.872568143525984 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/1939 12/18639 0.166666666666667 1.60211449200619 0.359513054843324 0.872568143525984 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/1939 12/18639 0.166666666666667 1.60211449200619 0.359513054843324 0.872568143525984 GO:0008237 metallopeptidase activity 21/1939 184/18639 0.114130434782609 1.09710014126511 0.360353306135299 0.872789192614601 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 10/1939 83/18639 0.120481927710843 1.15815505446231 0.361565617040689 0.873908597204155 GO:0030170 pyridoxal phosphate binding 7/1939 56/18639 0.125 1.20158586900464 0.363899537861731 0.877728698983264 GO:0019209 kinase activator activity 17/1939 148/18639 0.114864864864865 1.10415998773399 0.370636616047974 0.89029351571358 GO:0030295 protein kinase activator activity 16/1939 139/18639 0.115107913669065 1.10649633980284 0.373327445161273 0.89029351571358 GO:0140101 catalytic activity, acting on a tRNA 16/1939 139/18639 0.115107913669065 1.10649633980284 0.373327445161273 0.89029351571358 GO:0051219 phosphoprotein binding 11/1939 93/18639 0.118279569892473 1.13698447819794 0.373780509627839 0.89029351571358 GO:0010314 phosphatidylinositol-5-phosphate binding 3/1939 21/18639 0.142857142857143 1.37324099314816 0.375719732818004 0.89029351571358 GO:0015174 basic amino acid transmembrane transporter activity 3/1939 21/18639 0.142857142857143 1.37324099314816 0.375719732818004 0.89029351571358 GO:0051010 microtubule plus-end binding 3/1939 21/18639 0.142857142857143 1.37324099314816 0.375719732818004 0.89029351571358 GO:0072542 protein phosphatase activator activity 3/1939 21/18639 0.142857142857143 1.37324099314816 0.375719732818004 0.89029351571358 GO:0017018 myosin phosphatase activity 10/1939 84/18639 0.119047619047619 1.14436749429013 0.375986617794919 0.89029351571358 GO:0140658 ATP-dependent chromatin remodeler activity 18/1939 158/18639 0.113924050632911 1.09511623504221 0.378483933358886 0.894388484905031 GO:0015215 nucleotide transmembrane transporter activity 4/1939 30/18639 0.133333333333333 1.28169159360495 0.381139983391676 0.894388484905031 GO:0051721 protein phosphatase 2A binding 4/1939 30/18639 0.133333333333333 1.28169159360495 0.381139983391676 0.894388484905031 GO:0070566 adenylyltransferase activity 4/1939 30/18639 0.133333333333333 1.28169159360495 0.381139983391676 0.894388484905031 GO:0070279 vitamin B6 binding 7/1939 57/18639 0.12280701754386 1.18050541516245 0.381554572530301 0.894388484905031 GO:0140693 molecular condensate scaffold activity 6/1939 48/18639 0.125 1.20158586900464 0.382612794298294 0.895068083047213 GO:0004722 protein serine/threonine phosphatase activity 12/1939 103/18639 0.116504854368932 1.11992469344122 0.384581303880889 0.897870178399269 GO:0016247 channel regulator activity 19/1939 168/18639 0.113095238095238 1.08714911957563 0.385802350998389 0.898919477826246 GO:0050840 extracellular matrix binding 8/1939 67/18639 0.119402985074627 1.14778351666115 0.396368104748121 0.90456236995772 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/1939 13/18639 0.153846153846154 1.47887491569802 0.398318022135889 0.90456236995772 GO:0008035 high-density lipoprotein particle binding 2/1939 13/18639 0.153846153846154 1.47887491569802 0.398318022135889 0.90456236995772 GO:0008253 5'-nucleotidase activity 2/1939 13/18639 0.153846153846154 1.47887491569802 0.398318022135889 0.90456236995772 GO:0009982 pseudouridine synthase activity 2/1939 13/18639 0.153846153846154 1.47887491569802 0.398318022135889 0.90456236995772 GO:0019855 calcium channel inhibitor activity 2/1939 13/18639 0.153846153846154 1.47887491569802 0.398318022135889 0.90456236995772 GO:0035325 Toll-like receptor binding 2/1939 13/18639 0.153846153846154 1.47887491569802 0.398318022135889 0.90456236995772 GO:0043560 insulin receptor substrate binding 2/1939 13/18639 0.153846153846154 1.47887491569802 0.398318022135889 0.90456236995772 GO:0051011 microtubule minus-end binding 2/1939 13/18639 0.153846153846154 1.47887491569802 0.398318022135889 0.90456236995772 GO:0070700 BMP receptor binding 2/1939 13/18639 0.153846153846154 1.47887491569802 0.398318022135889 0.90456236995772 GO:0071714 icosanoid transmembrane transporter activity 2/1939 13/18639 0.153846153846154 1.47887491569802 0.398318022135889 0.90456236995772 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/1939 13/18639 0.153846153846154 1.47887491569802 0.398318022135889 0.90456236995772 GO:0089720 caspase binding 2/1939 13/18639 0.153846153846154 1.47887491569802 0.398318022135889 0.90456236995772 GO:0008276 protein methyltransferase activity 11/1939 95/18639 0.115789473684211 1.11304796286746 0.401267522735559 0.908632317244725 GO:0004532 RNA exonuclease activity 5/1939 40/18639 0.125 1.20158586900464 0.404212389981189 0.908632317244725 GO:0008970 phospholipase A1 activity 3/1939 22/18639 0.136363636363636 1.31082094800506 0.405064583070617 0.908632317244725 GO:0016881 acid-amino acid ligase activity 3/1939 22/18639 0.136363636363636 1.31082094800506 0.405064583070617 0.908632317244725 GO:0005310 dicarboxylic acid transmembrane transporter activity 4/1939 31/18639 0.129032258064516 1.24034670348866 0.405655677438081 0.908632317244725 GO:0047499 calcium-independent phospholipase A2 activity 4/1939 31/18639 0.129032258064516 1.24034670348866 0.405655677438081 0.908632317244725 GO:0070273 phosphatidylinositol-4-phosphate binding 4/1939 31/18639 0.129032258064516 1.24034670348866 0.405655677438081 0.908632317244725 GO:0141108 transporter regulator activity 19/1939 170/18639 0.111764705882353 1.07435912993356 0.40634973157468 0.908632317244725 GO:0003777 microtubule motor activity 8/1939 68/18639 0.117647058823529 1.13090434729849 0.412773813500767 0.921228913272785 GO:0045309 protein phosphorylated amino acid binding 7/1939 59/18639 0.11864406779661 1.14048828244508 0.416905182420231 0.928670243823268 GO:0017080 sodium channel regulator activity 5/1939 41/18639 0.121951219512195 1.17227889658989 0.425579074808562 0.942342228309652 GO:0047498 calcium-dependent phospholipase A2 activity 4/1939 32/18639 0.125 1.20158586900464 0.429975584336626 0.942342228309652 GO:0140142 nucleocytoplasmic carrier activity 4/1939 32/18639 0.125 1.20158586900464 0.429975584336626 0.942342228309652 GO:0003887 DNA-directed DNA polymerase activity 3/1939 23/18639 0.130434782608696 1.25382873287441 0.433987158768646 0.942342228309652 GO:0005158 insulin receptor binding 3/1939 23/18639 0.130434782608696 1.25382873287441 0.433987158768646 0.942342228309652 GO:0017134 fibroblast growth factor binding 3/1939 23/18639 0.130434782608696 1.25382873287441 0.433987158768646 0.942342228309652 GO:0031681 G-protein beta-subunit binding 3/1939 23/18639 0.130434782608696 1.25382873287441 0.433987158768646 0.942342228309652 GO:0042171 lysophosphatidic acid acyltransferase activity 3/1939 23/18639 0.130434782608696 1.25382873287441 0.433987158768646 0.942342228309652 GO:0071617 lysophospholipid acyltransferase activity 3/1939 23/18639 0.130434782608696 1.25382873287441 0.433987158768646 0.942342228309652 GO:0004705 JUN kinase activity 2/1939 14/18639 0.142857142857143 1.37324099314816 0.435984945114938 0.942342228309652 GO:0005344 oxygen carrier activity 2/1939 14/18639 0.142857142857143 1.37324099314816 0.435984945114938 0.942342228309652 GO:0008174 mRNA methyltransferase activity 2/1939 14/18639 0.142857142857143 1.37324099314816 0.435984945114938 0.942342228309652 GO:0019992 diacylglycerol binding 2/1939 14/18639 0.142857142857143 1.37324099314816 0.435984945114938 0.942342228309652 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 2/1939 14/18639 0.142857142857143 1.37324099314816 0.435984945114938 0.942342228309652 GO:0061665 SUMO ligase activity 2/1939 14/18639 0.142857142857143 1.37324099314816 0.435984945114938 0.942342228309652 GO:0070742 C2H2 zinc finger domain binding 2/1939 14/18639 0.142857142857143 1.37324099314816 0.435984945114938 0.942342228309652 GO:0033293 monocarboxylic acid binding 9/1939 79/18639 0.113924050632911 1.09511623504221 0.439509665075951 0.948201407062006 GO:0005048 signal sequence binding 6/1939 51/18639 0.117647058823529 1.13090434729849 0.44036404262412 0.948288557591682 GO:0019208 phosphatase regulator activity 13/1939 117/18639 0.111111111111111 1.06807632800413 0.444648631551396 0.953323233722926 GO:0097110 scaffold protein binding 8/1939 70/18639 0.114285714285714 1.09859279451853 0.445501016913807 0.953323233722926 GO:0140789 histone phosphatase activity 15/1939 136/18639 0.110294117647059 1.06022282559233 0.446039331612018 0.953323233722926 GO:0035198 miRNA binding 5/1939 42/18639 0.119047619047619 1.14436749429013 0.446793549882161 0.953323233722926 GO:0042056 chemoattractant activity 5/1939 42/18639 0.119047619047619 1.14436749429013 0.446793549882161 0.953323233722926 GO:0140311 protein sequestering activity 4/1939 33/18639 0.121212121212121 1.1651741760045 0.454020609308691 0.966972595694012 GO:0004721 phosphoprotein phosphatase activity 19/1939 175/18639 0.108571428571429 1.0436631547926 0.457981288779852 0.970485329822281 GO:0004622 lysophospholipase activity 3/1939 24/18639 0.125 1.20158586900464 0.462369955289795 0.970485329822281 GO:0005315 phosphate transmembrane transporter activity 3/1939 24/18639 0.125 1.20158586900464 0.462369955289795 0.970485329822281 GO:0030215 semaphorin receptor binding 3/1939 24/18639 0.125 1.20158586900464 0.462369955289795 0.970485329822281 GO:0035035 histone acetyltransferase binding 3/1939 24/18639 0.125 1.20158586900464 0.462369955289795 0.970485329822281 GO:0050699 WW domain binding 3/1939 24/18639 0.125 1.20158586900464 0.462369955289795 0.970485329822281 GO:0060229 lipase activator activity 3/1939 24/18639 0.125 1.20158586900464 0.462369955289795 0.970485329822281 GO:0070300 phosphatidic acid binding 3/1939 24/18639 0.125 1.20158586900464 0.462369955289795 0.970485329822281 GO:0004620 phospholipase activity 12/1939 109/18639 0.110091743119266 1.05827746260959 0.463398575685032 0.970485329822281 GO:0043130 ubiquitin binding 11/1939 100/18639 0.11 1.05739556472408 0.470043177206548 0.970485329822281 GO:0004953 icosanoid receptor activity 2/1939 15/18639 0.133333333333333 1.28169159360495 0.472330628334106 0.970485329822281 GO:0005041 low-density lipoprotein particle receptor activity 2/1939 15/18639 0.133333333333333 1.28169159360495 0.472330628334106 0.970485329822281 GO:0005523 tropomyosin binding 2/1939 15/18639 0.133333333333333 1.28169159360495 0.472330628334106 0.970485329822281 GO:0008252 nucleotidase activity 2/1939 15/18639 0.133333333333333 1.28169159360495 0.472330628334106 0.970485329822281 GO:0015116 sulfate transmembrane transporter activity 2/1939 15/18639 0.133333333333333 1.28169159360495 0.472330628334106 0.970485329822281 GO:0015929 hexosaminidase activity 2/1939 15/18639 0.133333333333333 1.28169159360495 0.472330628334106 0.970485329822281 GO:0016846 carbon-sulfur lyase activity 2/1939 15/18639 0.133333333333333 1.28169159360495 0.472330628334106 0.970485329822281 GO:0061578 K63-linked deubiquitinase activity 2/1939 15/18639 0.133333333333333 1.28169159360495 0.472330628334106 0.970485329822281 GO:0141050 histone H3K deacetylase activity 2/1939 15/18639 0.133333333333333 1.28169159360495 0.472330628334106 0.970485329822281 GO:0141051 histone H4K deacetylase activity 2/1939 15/18639 0.133333333333333 1.28169159360495 0.472330628334106 0.970485329822281 GO:0008175 tRNA methyltransferase activity 4/1939 34/18639 0.117647058823529 1.13090434729849 0.477719420038574 0.976391446219192 GO:0051427 hormone receptor binding 4/1939 34/18639 0.117647058823529 1.13090434729849 0.477719420038574 0.976391446219192 GO:0090482 vitamin transmembrane transporter activity 4/1939 34/18639 0.117647058823529 1.13090434729849 0.477719420038574 0.976391446219192 GO:0032182 ubiquitin-like protein binding 13/1939 120/18639 0.108333333333333 1.04137441980402 0.482283718939 0.98399392743246 GO:0043014 alpha-tubulin binding 5/1939 44/18639 0.113636363636364 1.09235079000422 0.488557546648176 0.993011115297854 GO:0019211 phosphatase activator activity 3/1939 25/18639 0.12 1.15352243424446 0.490112782228555 0.993011115297854 GO:0042974 nuclear retinoic acid receptor binding 3/1939 25/18639 0.12 1.15352243424446 0.490112782228555 0.993011115297854 GO:0047617 fatty acyl-CoA hydrolase activity 3/1939 25/18639 0.12 1.15352243424446 0.490112782228555 0.993011115297854 GO:0003925 G protein activity 6/1939 54/18639 0.111111111111111 1.06807632800413 0.496990977639518 0.999999999881418 GO:0008238 exopeptidase activity 11/1939 102/18639 0.107843137254902 1.03666231835695 0.497237798544407 0.999999999881418 GO:0000175 3'-5'-RNA exonuclease activity 4/1939 35/18639 0.114285714285714 1.09859279451853 0.501008358921607 0.999999999881418 GO:0004623 phospholipase A2 activity 4/1939 35/18639 0.114285714285714 1.09859279451853 0.501008358921607 0.999999999881418 GO:0099106 ion channel regulator activity 17/1939 160/18639 0.10625 1.02134798865395 0.501438728404319 0.999999999881418 GO:0004707 MAP kinase activity 2/1939 16/18639 0.125 1.20158586900464 0.507222266765983 0.999999999881418 GO:0004708 MAP kinase kinase activity 2/1939 16/18639 0.125 1.20158586900464 0.507222266765983 0.999999999881418 GO:0005521 lamin binding 2/1939 16/18639 0.125 1.20158586900464 0.507222266765983 0.999999999881418 GO:0030275 LRR domain binding 2/1939 16/18639 0.125 1.20158586900464 0.507222266765983 0.999999999881418 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1939 16/18639 0.125 1.20158586900464 0.507222266765983 0.999999999881418 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/1939 16/18639 0.125 1.20158586900464 0.507222266765983 0.999999999881418 GO:0051015 actin filament binding 22/1939 209/18639 0.105263157894737 1.01186178442496 0.510213231201281 0.999999999881418 GO:0004860 protein kinase inhibitor activity 9/1939 84/18639 0.107142857142857 1.02993074486112 0.515124019641869 0.999999999881418 GO:0005160 transforming growth factor beta receptor binding 3/1939 26/18639 0.115384615384615 1.10915618677352 0.517131649962788 0.999999999881418 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/1939 26/18639 0.115384615384615 1.10915618677352 0.517131649962788 0.999999999881418 GO:0008157 protein phosphatase 1 binding 3/1939 26/18639 0.115384615384615 1.10915618677352 0.517131649962788 0.999999999881418 GO:0016289 acyl-CoA hydrolase activity 3/1939 26/18639 0.115384615384615 1.10915618677352 0.517131649962788 0.999999999881418 GO:0070412 R-SMAD binding 3/1939 26/18639 0.115384615384615 1.10915618677352 0.517131649962788 0.999999999881418 GO:0120013 lipid transfer activity 7/1939 65/18639 0.107692307692308 1.03521244098861 0.520878992920284 0.999999999881418 GO:0004869 cysteine-type endopeptidase inhibitor activity 4/1939 36/18639 0.111111111111111 1.06807632800413 0.523831267097344 0.999999999881418 GO:0005484 SNAP receptor activity 4/1939 36/18639 0.111111111111111 1.06807632800413 0.523831267097344 0.999999999881418 GO:0030291 protein serine/threonine kinase inhibitor activity 5/1939 46/18639 0.108695652173913 1.04485727739534 0.529129686447344 0.999999999881418 GO:0008235 metalloexopeptidase activity 7/1939 66/18639 0.106060606060606 1.01952740400394 0.537596816602272 0.999999999881418 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/1939 17/18639 0.117647058823529 1.13090434729849 0.540568952985492 0.999999999881418 GO:0005092 GDP-dissociation inhibitor activity 2/1939 17/18639 0.117647058823529 1.13090434729849 0.540568952985492 0.999999999881418 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/1939 17/18639 0.117647058823529 1.13090434729849 0.540568952985492 0.999999999881418 GO:0016805 dipeptidase activity 2/1939 17/18639 0.117647058823529 1.13090434729849 0.540568952985492 0.999999999881418 GO:0032183 SUMO binding 2/1939 17/18639 0.117647058823529 1.13090434729849 0.540568952985492 0.999999999881418 GO:0036041 long-chain fatty acid binding 2/1939 17/18639 0.117647058823529 1.13090434729849 0.540568952985492 0.999999999881418 GO:0038191 neuropilin binding 2/1939 17/18639 0.117647058823529 1.13090434729849 0.540568952985492 0.999999999881418 GO:0045125 bioactive lipid receptor activity 2/1939 17/18639 0.117647058823529 1.13090434729849 0.540568952985492 0.999999999881418 GO:0046965 nuclear retinoid X receptor binding 2/1939 17/18639 0.117647058823529 1.13090434729849 0.540568952985492 0.999999999881418 GO:0005506 iron ion binding 16/1939 154/18639 0.103896103896104 0.998720722289572 0.541287847276269 0.999999999881418 GO:0008266 poly(U) RNA binding 3/1939 27/18639 0.111111111111111 1.06807632800413 0.543357574243531 0.999999999881418 GO:0008320 protein transmembrane transporter activity 3/1939 27/18639 0.111111111111111 1.06807632800413 0.543357574243531 0.999999999881418 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/1939 27/18639 0.111111111111111 1.06807632800413 0.543357574243531 0.999999999881418 GO:0035255 ionotropic glutamate receptor binding 3/1939 27/18639 0.111111111111111 1.06807632800413 0.543357574243531 0.999999999881418 GO:0001784 phosphotyrosine residue binding 5/1939 47/18639 0.106382978723404 1.02262627149331 0.548870094372048 0.999999999881418 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 4/1939 38/18639 0.105263157894737 1.01186178442496 0.567890308280714 0.999999999881418 GO:0061980 regulatory RNA binding 6/1939 58/18639 0.103448275862069 0.994415891590048 0.569089173508487 0.999999999881418 GO:0008308 voltage-gated monoatomic anion channel activity 2/1939 18/18639 0.111111111111111 1.06807632800413 0.572314404644594 0.999999999881418 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/1939 18/18639 0.111111111111111 1.06807632800413 0.572314404644594 0.999999999881418 GO:0030228 lipoprotein particle receptor activity 2/1939 18/18639 0.111111111111111 1.06807632800413 0.572314404644594 0.999999999881418 GO:0032393 MHC class I receptor activity 2/1939 18/18639 0.111111111111111 1.06807632800413 0.572314404644594 0.999999999881418 GO:0050811 GABA receptor binding 2/1939 18/18639 0.111111111111111 1.06807632800413 0.572314404644594 0.999999999881418 GO:0008170 N-methyltransferase activity 10/1939 98/18639 0.102040816326531 0.980886423677258 0.574685018468189 0.999999999881418 GO:0042626 ATPase-coupled transmembrane transporter activity 10/1939 98/18639 0.102040816326531 0.980886423677258 0.574685018468189 0.999999999881418 GO:0008080 N-acetyltransferase activity 7/1939 69/18639 0.101449275362319 0.975200125568984 0.586221988220177 0.999999999881418 GO:0070063 RNA polymerase binding 6/1939 59/18639 0.101694915254237 0.977561384952929 0.5863175498581 0.999999999881418 GO:0070888 E-box binding 6/1939 59/18639 0.101694915254237 0.977561384952929 0.5863175498581 0.999999999881418 GO:0004629 phospholipase C activity 3/1939 29/18639 0.103448275862069 0.994415891590048 0.593222264103763 0.999999999881418 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 3/1939 29/18639 0.103448275862069 0.994415891590048 0.593222264103763 0.999999999881418 GO:0043236 laminin binding 3/1939 29/18639 0.103448275862069 0.994415891590048 0.593222264103763 0.999999999881418 GO:0097472 cyclin-dependent protein kinase activity 3/1939 29/18639 0.103448275862069 0.994415891590048 0.593222264103763 0.999999999881418 GO:0106222 lncRNA binding 3/1939 29/18639 0.103448275862069 0.994415891590048 0.593222264103763 0.999999999881418 GO:0019210 kinase inhibitor activity 9/1939 90/18639 0.1 0.961268695203713 0.600981472992978 0.999999999881418 GO:0008574 plus-end-directed microtubule motor activity 2/1939 19/18639 0.105263157894737 1.01186178442496 0.602430750448503 0.999999999881418 GO:0015245 fatty acid transmembrane transporter activity 2/1939 19/18639 0.105263157894737 1.01186178442496 0.602430750448503 0.999999999881418 GO:0031420 alkali metal ion binding 2/1939 19/18639 0.105263157894737 1.01186178442496 0.602430750448503 0.999999999881418 GO:0046624 sphingolipid transporter activity 2/1939 19/18639 0.105263157894737 1.01186178442496 0.602430750448503 0.999999999881418 GO:1990380 K48-linked deubiquitinase activity 2/1939 19/18639 0.105263157894737 1.01186178442496 0.602430750448503 0.999999999881418 GO:0016798 hydrolase activity, acting on glycosyl bonds 13/1939 130/18639 0.1 0.961268695203713 0.602559875507435 0.999999999881418 GO:0061791 GTPase motor activity 4/1939 40/18639 0.1 0.961268695203713 0.609586535254721 0.999999999881418 GO:1990606 membrane scission GTPase motor activity 4/1939 40/18639 0.1 0.961268695203713 0.609586535254721 0.999999999881418 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 3/1939 30/18639 0.1 0.961268695203713 0.616786961960662 0.999999999881418 GO:0031624 ubiquitin conjugating enzyme binding 3/1939 30/18639 0.1 0.961268695203713 0.616786961960662 0.999999999881418 GO:0033612 receptor serine/threonine kinase binding 3/1939 30/18639 0.1 0.961268695203713 0.616786961960662 0.999999999881418 GO:0015026 coreceptor activity 6/1939 61/18639 0.0983606557377049 0.945510192003652 0.619667045557732 0.999999999881418 GO:0016597 amino acid binding 5/1939 51/18639 0.0980392156862745 0.942420289415405 0.623486121808281 0.999999999881418 GO:0005200 structural constituent of cytoskeleton 11/1939 112/18639 0.0982142857142857 0.944103182789361 0.62586190170295 0.999999999881418 GO:0016877 ligase activity, forming carbon-sulfur bonds 4/1939 41/18639 0.0975609756097561 0.937823117271915 0.629479233681332 0.999999999881418 GO:0140318 protein transporter activity 4/1939 41/18639 0.0975609756097561 0.937823117271915 0.629479233681332 0.999999999881418 GO:0003924 GTPase activity 33/1939 331/18639 0.0996978851963746 0.958364560172886 0.629555987414968 0.999999999881418 GO:0005326 neurotransmitter transmembrane transporter activity 2/1939 20/18639 0.1 0.961268695203713 0.630913233274275 0.999999999881418 GO:0031418 L-ascorbic acid binding 2/1939 20/18639 0.1 0.961268695203713 0.630913233274275 0.999999999881418 GO:0140939 histone H4 methyltransferase activity 2/1939 20/18639 0.1 0.961268695203713 0.630913233274275 0.999999999881418 GO:0005518 collagen binding 7/1939 72/18639 0.0972222222222222 0.93456678700361 0.63217495307748 0.999999999881418 GO:0016878 acid-thiol ligase activity 3/1939 31/18639 0.0967741935483871 0.930260027616497 0.639408171016653 0.999999999881418 GO:0072349 modified amino acid transmembrane transporter activity 3/1939 31/18639 0.0967741935483871 0.930260027616497 0.639408171016653 0.999999999881418 GO:0019894 kinesin binding 4/1939 42/18639 0.0952380952380952 0.915493995432108 0.648709305660192 0.999999999881418 GO:1901681 sulfur compound binding 27/1939 275/18639 0.0981818181818182 0.943791082563646 0.654713086132649 0.999999999881418 GO:0015297 antiporter activity 13/1939 135/18639 0.0962962962962963 0.925666150936909 0.657667331469457 0.999999999881418 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/1939 21/18639 0.0952380952380952 0.915493995432108 0.657775707006514 0.999999999881418 GO:0061891 calcium ion sensor activity 2/1939 21/18639 0.0952380952380952 0.915493995432108 0.657775707006514 0.999999999881418 GO:1904047 S-adenosyl-L-methionine binding 2/1939 21/18639 0.0952380952380952 0.915493995432108 0.657775707006514 0.999999999881418 GO:0022884 macromolecule transmembrane transporter activity 3/1939 32/18639 0.09375 0.901189401753481 0.661073611018035 0.999999999881418 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/1939 32/18639 0.09375 0.901189401753481 0.661073611018035 0.999999999881418 GO:0042910 xenobiotic transmembrane transporter activity 3/1939 32/18639 0.09375 0.901189401753481 0.661073611018035 0.999999999881418 GO:0043425 bHLH transcription factor binding 3/1939 32/18639 0.09375 0.901189401753481 0.661073611018035 0.999999999881418 GO:0120015 sterol transfer activity 3/1939 32/18639 0.09375 0.901189401753481 0.661073611018035 0.999999999881418 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0004935 adrenergic receptor activity 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0005031 tumor necrosis factor receptor activity 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0005381 iron ion transmembrane transporter activity 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0008140 cAMP response element binding protein binding 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0008190 eukaryotic initiation factor 4E binding 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0008239 dipeptidyl-peptidase activity 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0015203 polyamine transmembrane transporter activity 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0016427 tRNA (cytidine) methyltransferase activity 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0019911 structural constituent of myelin sheath 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0031419 cobalamin binding 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0031434 mitogen-activated protein kinase kinase binding 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0031996 thioesterase binding 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0035374 chondroitin sulfate binding 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0042975 peroxisome proliferator activated receptor binding 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0050308 sugar-phosphatase activity 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0051880 G-quadruplex DNA binding 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0099122 RNA polymerase II C-terminal domain binding 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0140135 mechanosensitive monoatomic cation channel activity 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:1905394 retromer complex binding 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:1990763 arrestin family protein binding 1/1939 10/18639 0.1 0.961268695203713 0.66671417447654 0.999999999881418 GO:0019003 GDP binding 7/1939 75/18639 0.0933333333333333 0.897184115523466 0.675087021444902 0.999999999881418 GO:0160215 deacylase activity 6/1939 65/18639 0.0923076923076923 0.887324949418812 0.681518856898169 0.999999999881418 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/1939 33/18639 0.0909090909090909 0.873880632003376 0.68177891118897 0.999999999881418 GO:0019239 deaminase activity 3/1939 33/18639 0.0909090909090909 0.873880632003376 0.68177891118897 0.999999999881418 GO:0071889 14-3-3 protein binding 3/1939 33/18639 0.0909090909090909 0.873880632003376 0.68177891118897 0.999999999881418 GO:0004407 histone deacetylase activity 2/1939 22/18639 0.0909090909090909 0.873880632003376 0.683046819400103 0.999999999881418 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 2/1939 22/18639 0.0909090909090909 0.873880632003376 0.683046819400103 0.999999999881418 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/1939 22/18639 0.0909090909090909 0.873880632003376 0.683046819400103 0.999999999881418 GO:0033558 protein lysine deacetylase activity 2/1939 22/18639 0.0909090909090909 0.873880632003376 0.683046819400103 0.999999999881418 GO:0140035 ubiquitin-like protein reader activity 2/1939 22/18639 0.0909090909090909 0.873880632003376 0.683046819400103 0.999999999881418 GO:0140784 metal ion sensor activity 2/1939 22/18639 0.0909090909090909 0.873880632003376 0.683046819400103 0.999999999881418 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 22/1939 229/18639 0.0960698689956332 0.92348957617824 0.685993676610946 0.999999999881418 GO:0008374 O-acyltransferase activity 5/1939 55/18639 0.0909090909090909 0.873880632003376 0.690184546039074 0.999999999881418 GO:0140313 molecular sequestering activity 5/1939 55/18639 0.0909090909090909 0.873880632003376 0.690184546039074 0.999999999881418 GO:0000099 sulfur amino acid transmembrane transporter activity 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0004016 adenylate cyclase activity 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0005114 type II transforming growth factor beta receptor binding 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0005536 D-glucose binding 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0008271 secondary active sulfate transmembrane transporter activity 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0008432 JUN kinase binding 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0019107 myristoyltransferase activity 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0019203 carbohydrate phosphatase activity 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0032050 clathrin heavy chain binding 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0032794 GTPase activating protein binding 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0034056 estrogen response element binding 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0035252 UDP-xylosyltransferase activity 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0042285 xylosyltransferase activity 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0043522 leucine zipper domain binding 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0047676 arachidonate-CoA ligase activity 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0048185 activin binding 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0048407 platelet-derived growth factor binding 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0140537 transcription regulator activator activity 1/1939 11/18639 0.0909090909090909 0.873880632003376 0.701404239197673 0.999999999881418 GO:0046915 transition metal ion transmembrane transporter activity 4/1939 45/18639 0.0888888888888889 0.854461062403301 0.702317002376434 0.999999999881418 GO:0004725 protein tyrosine phosphatase activity 9/1939 98/18639 0.0918367346938776 0.882797781309533 0.70241979842334 0.999999999881418 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/1939 23/18639 0.0869565217391304 0.835885821916272 0.70676678707929 0.999999999881418 GO:0004197 cysteine-type endopeptidase activity 8/1939 88/18639 0.0909090909090909 0.873880632003376 0.707902478553553 0.999999999881418 GO:0005539 glycosaminoglycan binding 23/1939 242/18639 0.0950413223140496 0.91360247891262 0.708175771404591 0.999999999881418 GO:0042054 histone methyltransferase activity 6/1939 67/18639 0.0895522388059701 0.860837637495863 0.709862296463088 0.999999999881418 GO:0016298 lipase activity 12/1939 130/18639 0.0923076923076923 0.887324949418812 0.711529250682493 0.999999999881418 GO:0008201 heparin binding 16/1939 172/18639 0.0930232558139535 0.894203437398803 0.718743259557293 0.999999999881418 GO:0004180 carboxypeptidase activity 4/1939 46/18639 0.0869565217391304 0.835885821916272 0.718811032464919 0.999999999881418 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 8/1939 89/18639 0.0898876404494382 0.86406174849772 0.71982641673694 0.999999999881418 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 8/1939 89/18639 0.0898876404494382 0.86406174849772 0.71982641673694 0.999999999881418 GO:0016229 steroid dehydrogenase activity 3/1939 35/18639 0.0857142857142857 0.823944595888897 0.720325189345881 0.999999999881418 GO:0043015 gamma-tubulin binding 3/1939 35/18639 0.0857142857142857 0.823944595888897 0.720325189345881 0.999999999881418 GO:0140566 histone reader activity 3/1939 35/18639 0.0857142857142857 0.823944595888897 0.720325189345881 0.999999999881418 GO:0005548 phospholipid transporter activity 6/1939 68/18639 0.0882352941176471 0.848178260473865 0.723369465372273 0.999999999881418 GO:0015295 solute:proton symporter activity 2/1939 24/18639 0.0833333333333333 0.801057246003094 0.728984680878335 0.999999999881418 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/1939 24/18639 0.0833333333333333 0.801057246003094 0.728984680878335 0.999999999881418 GO:0140793 histone H2AXY142 phosphatase activity 8/1939 90/18639 0.0888888888888889 0.854461062403301 0.731421045394888 0.999999999881418 GO:0004126 cytidine deaminase activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0005049 nuclear export signal receptor activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0005078 MAP-kinase scaffold activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0005095 GTPase inhibitor activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0005165 neurotrophin receptor binding 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0005436 sodium:phosphate symporter activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0008504 monoamine transmembrane transporter activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0015368 calcium:monoatomic cation antiporter activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0016273 arginine N-methyltransferase activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0016274 protein-arginine N-methyltransferase activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0031543 peptidyl-proline dioxygenase activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0035197 siRNA binding 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0035259 nuclear glucocorticoid receptor binding 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0070008 serine-type exopeptidase activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0070679 inositol 1,4,5 trisphosphate binding 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:1990459 transferrin receptor binding 1/1939 12/18639 0.0833333333333333 0.801057246003094 0.73248525595716 0.999999999881418 GO:0003774 cytoskeletal motor activity 14/1939 153/18639 0.0915032679738562 0.879592270121045 0.732945120241499 0.999999999881418 GO:0043495 protein-membrane adaptor activity 4/1939 47/18639 0.0851063829787234 0.81810101719465 0.734619491822396 0.999999999881418 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 11/1939 122/18639 0.0901639344262295 0.866717676003348 0.735350065087011 0.999999999881418 GO:0016409 palmitoyltransferase activity 3/1939 36/18639 0.0833333333333333 0.801057246003094 0.738188273186657 0.999999999881418 GO:0045505 dynein intermediate chain binding 3/1939 36/18639 0.0833333333333333 0.801057246003094 0.738188273186657 0.999999999881418 GO:1901981 phosphatidylinositol phosphate binding 17/1939 185/18639 0.0918918918918919 0.883327990187196 0.741057079819127 0.999999999881418 GO:0000030 mannosyltransferase activity 2/1939 25/18639 0.08 0.769014956162971 0.749756150326142 0.999999999881418 GO:0005537 D-mannose binding 2/1939 25/18639 0.08 0.769014956162971 0.749756150326142 0.999999999881418 GO:0008139 nuclear localization sequence binding 2/1939 25/18639 0.08 0.769014956162971 0.749756150326142 0.999999999881418 GO:0015645 fatty acid ligase activity 2/1939 25/18639 0.08 0.769014956162971 0.749756150326142 0.999999999881418 GO:0017056 structural constituent of nuclear pore 2/1939 25/18639 0.08 0.769014956162971 0.749756150326142 0.999999999881418 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/1939 25/18639 0.08 0.769014956162971 0.749756150326142 0.999999999881418 GO:0019707 protein-cysteine S-acyltransferase activity 2/1939 25/18639 0.08 0.769014956162971 0.749756150326142 0.999999999881418 GO:0120020 cholesterol transfer activity 2/1939 25/18639 0.08 0.769014956162971 0.749756150326142 0.999999999881418 GO:0120515 fatty acid-CoA ligase activity 2/1939 25/18639 0.08 0.769014956162971 0.749756150326142 0.999999999881418 GO:0030971 receptor tyrosine kinase binding 7/1939 81/18639 0.0864197530864197 0.830726032892098 0.750965888434316 0.999999999881418 GO:0019213 deacetylase activity 3/1939 37/18639 0.0810810810810811 0.779407050165173 0.755133776381069 0.999999999881418 GO:0042805 actinin binding 3/1939 37/18639 0.0810810810810811 0.779407050165173 0.755133776381069 0.999999999881418 GO:0043394 proteoglycan binding 3/1939 37/18639 0.0810810810810811 0.779407050165173 0.755133776381069 0.999999999881418 GO:0004535 poly(A)-specific ribonuclease activity 1/1939 13/18639 0.0769230769230769 0.73943745784901 0.760332525442266 0.999999999881418 GO:0005035 death receptor activity 1/1939 13/18639 0.0769230769230769 0.73943745784901 0.760332525442266 0.999999999881418 GO:0008417 fucosyltransferase activity 1/1939 13/18639 0.0769230769230769 0.73943745784901 0.760332525442266 0.999999999881418 GO:0030955 potassium ion binding 1/1939 13/18639 0.0769230769230769 0.73943745784901 0.760332525442266 0.999999999881418 GO:0031432 titin binding 1/1939 13/18639 0.0769230769230769 0.73943745784901 0.760332525442266 0.999999999881418 GO:0032396 inhibitory MHC class I receptor activity 1/1939 13/18639 0.0769230769230769 0.73943745784901 0.760332525442266 0.999999999881418 GO:0035673 oligopeptide transmembrane transporter activity 1/1939 13/18639 0.0769230769230769 0.73943745784901 0.760332525442266 0.999999999881418 GO:0045159 myosin II binding 1/1939 13/18639 0.0769230769230769 0.73943745784901 0.760332525442266 0.999999999881418 GO:0071837 HMG box domain binding 1/1939 13/18639 0.0769230769230769 0.73943745784901 0.760332525442266 0.999999999881418 GO:0097157 pre-mRNA intronic binding 1/1939 13/18639 0.0769230769230769 0.73943745784901 0.760332525442266 0.999999999881418 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1939 13/18639 0.0769230769230769 0.73943745784901 0.760332525442266 0.999999999881418 GO:0140852 histone ubiquitin ligase activity 1/1939 13/18639 0.0769230769230769 0.73943745784901 0.760332525442266 0.999999999881418 GO:0035254 glutamate receptor binding 4/1939 49/18639 0.0816326530612245 0.784709138941807 0.764206119798688 0.999999999881418 GO:0001637 G protein-coupled chemoattractant receptor activity 2/1939 26/18639 0.0769230769230769 0.73943745784901 0.769141525356421 0.999999999881418 GO:0004435 phosphatidylinositol phospholipase C activity 2/1939 26/18639 0.0769230769230769 0.73943745784901 0.769141525356421 0.999999999881418 GO:0004950 chemokine receptor activity 2/1939 26/18639 0.0769230769230769 0.73943745784901 0.769141525356421 0.999999999881418 GO:0008143 poly(A) binding 2/1939 26/18639 0.0769230769230769 0.73943745784901 0.769141525356421 0.999999999881418 GO:0030247 polysaccharide binding 2/1939 26/18639 0.0769230769230769 0.73943745784901 0.769141525356421 0.999999999881418 GO:0051139 metal cation:proton antiporter activity 2/1939 26/18639 0.0769230769230769 0.73943745784901 0.769141525356421 0.999999999881418 GO:0097602 cullin family protein binding 2/1939 26/18639 0.0769230769230769 0.73943745784901 0.769141525356421 0.999999999881418 GO:0042887 amide transmembrane transporter activity 3/1939 38/18639 0.0789473684210526 0.758896338318721 0.771183216503956 0.999999999881418 GO:0016791 phosphatase activity 25/1939 273/18639 0.0915750915750916 0.880282687915488 0.779007223395018 0.999999999881418 GO:0019783 ubiquitin-like protein peptidase activity 11/1939 127/18639 0.0866141732283465 0.83259493285361 0.781331884813976 0.999999999881418 GO:0005545 1-phosphatidylinositol binding 1/1939 14/18639 0.0714285714285714 0.686620496574081 0.785282339313598 0.999999999881418 GO:0008392 arachidonate epoxygenase activity 1/1939 14/18639 0.0714285714285714 0.686620496574081 0.785282339313598 0.999999999881418 GO:0008494 translation activator activity 1/1939 14/18639 0.0714285714285714 0.686620496574081 0.785282339313598 0.999999999881418 GO:0008559 ABC-type xenobiotic transporter activity 1/1939 14/18639 0.0714285714285714 0.686620496574081 0.785282339313598 0.999999999881418 GO:0015386 potassium:proton antiporter activity 1/1939 14/18639 0.0714285714285714 0.686620496574081 0.785282339313598 0.999999999881418 GO:0032036 myosin heavy chain binding 1/1939 14/18639 0.0714285714285714 0.686620496574081 0.785282339313598 0.999999999881418 GO:0034236 protein kinase A catalytic subunit binding 1/1939 14/18639 0.0714285714285714 0.686620496574081 0.785282339313598 0.999999999881418 GO:0043176 amine binding 1/1939 14/18639 0.0714285714285714 0.686620496574081 0.785282339313598 0.999999999881418 GO:0044548 S100 protein binding 1/1939 14/18639 0.0714285714285714 0.686620496574081 0.785282339313598 0.999999999881418 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/1939 14/18639 0.0714285714285714 0.686620496574081 0.785282339313598 0.999999999881418 GO:1901474 azole transmembrane transporter activity 1/1939 14/18639 0.0714285714285714 0.686620496574081 0.785282339313598 0.999999999881418 GO:0016405 CoA-ligase activity 2/1939 27/18639 0.0740740740740741 0.712050885336084 0.787204241445452 0.999999999881418 GO:0016407 acetyltransferase activity 8/1939 96/18639 0.0833333333333333 0.801057246003094 0.794040883897179 0.999999999881418 GO:0035064 methylated histone binding 6/1939 74/18639 0.0810810810810811 0.779407050165173 0.795107887934021 0.999999999881418 GO:0005178 integrin binding 14/1939 161/18639 0.0869565217391304 0.835885821916272 0.79754581978446 0.999999999881418 GO:1901682 sulfur compound transmembrane transporter activity 5/1939 63/18639 0.0793650793650794 0.76291166286009 0.797981759953494 0.999999999881418 GO:0071949 FAD binding 3/1939 40/18639 0.075 0.720951521402785 0.80069412721575 0.999999999881418 GO:0045499 chemorepellent activity 2/1939 28/18639 0.0714285714285714 0.686620496574081 0.80400954148179 0.999999999881418 GO:0046875 ephrin receptor binding 2/1939 28/18639 0.0714285714285714 0.686620496574081 0.80400954148179 0.999999999881418 GO:0051019 mitogen-activated protein kinase binding 2/1939 28/18639 0.0714285714285714 0.686620496574081 0.80400954148179 0.999999999881418 GO:0051393 alpha-actinin binding 2/1939 28/18639 0.0714285714285714 0.686620496574081 0.80400954148179 0.999999999881418 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/1939 28/18639 0.0714285714285714 0.686620496574081 0.80400954148179 0.999999999881418 GO:0004089 carbonate dehydratase activity 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0004467 long-chain fatty acid-CoA ligase activity 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0008020 G protein-coupled photoreceptor activity 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0008242 omega peptidase activity 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0010181 FMN binding 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0017081 chloride channel regulator activity 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0033130 acetylcholine receptor binding 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0034483 heparan sulfate sulfotransferase activity 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0042809 nuclear vitamin D receptor binding 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0045504 dynein heavy chain binding 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0051371 muscle alpha-actinin binding 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0140776 protein-containing complex destabilizing activity 1/1939 15/18639 0.0666666666666667 0.640845796802475 0.807636032954991 0.999999999881418 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/1939 41/18639 0.0731707317073171 0.703367337953936 0.814211092494782 0.999999999881418 GO:0140034 methylation-dependent protein binding 6/1939 76/18639 0.0789473684210526 0.758896338318721 0.815562206308785 0.999999999881418 GO:0005544 calcium-dependent phospholipid binding 4/1939 53/18639 0.0754716981132075 0.725485807700916 0.815573325112176 0.999999999881418 GO:0016251 RNA polymerase II general transcription initiation factor activity 4/1939 53/18639 0.0754716981132075 0.725485807700916 0.815573325112176 0.999999999881418 GO:0034212 protein N-acetyltransferase activity 4/1939 53/18639 0.0754716981132075 0.725485807700916 0.815573325112176 0.999999999881418 GO:0016417 S-acyltransferase activity 2/1939 29/18639 0.0689655172413793 0.662943927726699 0.819623413880162 0.999999999881418 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/1939 29/18639 0.0689655172413793 0.662943927726699 0.819623413880162 0.999999999881418 GO:0004222 metalloendopeptidase activity 9/1939 110/18639 0.0818181818181818 0.786492568803038 0.820455007437617 0.999999999881418 GO:0015485 cholesterol binding 4/1939 54/18639 0.0740740740740741 0.712050885336084 0.826875281846613 0.999999999881418 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/1939 16/18639 0.0625 0.600792934502321 0.827663617367591 0.999999999881418 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/1939 16/18639 0.0625 0.600792934502321 0.827663617367591 0.999999999881418 GO:0008391 arachidonate monooxygenase activity 1/1939 16/18639 0.0625 0.600792934502321 0.827663617367591 0.999999999881418 GO:0015385 sodium:proton antiporter activity 1/1939 16/18639 0.0625 0.600792934502321 0.827663617367591 0.999999999881418 GO:0015562 efflux transmembrane transporter activity 1/1939 16/18639 0.0625 0.600792934502321 0.827663617367591 0.999999999881418 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1939 16/18639 0.0625 0.600792934502321 0.827663617367591 0.999999999881418 GO:0019841 retinol binding 1/1939 16/18639 0.0625 0.600792934502321 0.827663617367591 0.999999999881418 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/1939 16/18639 0.0625 0.600792934502321 0.827663617367591 0.999999999881418 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/1939 16/18639 0.0625 0.600792934502321 0.827663617367591 0.999999999881418 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/1939 16/18639 0.0625 0.600792934502321 0.827663617367591 0.999999999881418 GO:0070411 I-SMAD binding 1/1939 16/18639 0.0625 0.600792934502321 0.827663617367591 0.999999999881418 GO:1902936 phosphatidylinositol bisphosphate binding 9/1939 111/18639 0.0810810810810811 0.779407050165173 0.828417896674841 0.999999999881418 GO:0008234 cysteine-type peptidase activity 16/1939 187/18639 0.0855614973262032 0.822475888944354 0.828906240603849 0.999999999881418 GO:0019955 cytokine binding 12/1939 144/18639 0.0833333333333333 0.801057246003094 0.829391351704698 0.999999999881418 GO:0003730 mRNA 3'-UTR binding 23/1939 262/18639 0.0877862595419847 0.843861831667382 0.833587170650292 0.999999999881418 GO:0001965 G-protein alpha-subunit binding 2/1939 30/18639 0.0666666666666667 0.640845796802475 0.834111731874412 0.999999999881418 GO:0046943 carboxylic acid transmembrane transporter activity 16/1939 188/18639 0.0851063829787234 0.81810101719465 0.834931652768178 0.999999999881418 GO:0001216 DNA-binding transcription activator activity 45/1939 491/18639 0.0916496945010183 0.880999822488128 0.837790521192314 0.999999999881418 GO:0008375 acetylglucosaminyltransferase activity 3/1939 43/18639 0.0697674418604651 0.670652578049102 0.838917861840279 0.999999999881418 GO:0005342 organic acid transmembrane transporter activity 16/1939 189/18639 0.0846560846560847 0.813772440384096 0.840797069873063 0.999999999881418 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/1939 17/18639 0.0588235294117647 0.565452173649243 0.845607033891473 0.999999999881418 GO:0009881 photoreceptor activity 1/1939 17/18639 0.0588235294117647 0.565452173649243 0.845607033891473 0.999999999881418 GO:0019198 transmembrane receptor protein phosphatase activity 1/1939 17/18639 0.0588235294117647 0.565452173649243 0.845607033891473 0.999999999881418 GO:0030548 acetylcholine receptor regulator activity 1/1939 17/18639 0.0588235294117647 0.565452173649243 0.845607033891473 0.999999999881418 GO:0031489 myosin V binding 1/1939 17/18639 0.0588235294117647 0.565452173649243 0.845607033891473 0.999999999881418 GO:0045236 CXCR chemokine receptor binding 1/1939 17/18639 0.0588235294117647 0.565452173649243 0.845607033891473 0.999999999881418 GO:0051787 misfolded protein binding 1/1939 17/18639 0.0588235294117647 0.565452173649243 0.845607033891473 0.999999999881418 GO:0070402 NADPH binding 1/1939 17/18639 0.0588235294117647 0.565452173649243 0.845607033891473 0.999999999881418 GO:0016411 acylglycerol O-acyltransferase activity 2/1939 31/18639 0.0645161290322581 0.620173351744331 0.847539563657706 0.999999999881418 GO:0170055 lipid transmembrane transporter activity 4/1939 56/18639 0.0714285714285714 0.686620496574081 0.84775480196984 0.999999999881418 GO:0032934 sterol binding 5/1939 68/18639 0.0735294117647059 0.706815217061554 0.84879251152343 0.999999999881418 GO:0001223 transcription coactivator binding 3/1939 44/18639 0.0681818181818182 0.655410474002532 0.850170305975401 0.999999999881418 GO:0043178 alcohol binding 7/1939 92/18639 0.0760869565217391 0.731400094176738 0.855378591818583 0.999999999881418 GO:0101005 deubiquitinase activity 9/1939 115/18639 0.0782608695652174 0.752297239724645 0.857560180902666 0.999999999881418 GO:0016279 protein-lysine N-methyltransferase activity 5/1939 69/18639 0.072463768115942 0.69657151826356 0.857570744465656 0.999999999881418 GO:0001217 DNA-binding transcription repressor activity 24/1939 278/18639 0.0863309352517986 0.829872254852127 0.859488958682181 0.999999999881418 GO:0070717 poly-purine tract binding 2/1939 32/18639 0.0625 0.600792934502321 0.859970627167017 0.999999999881418 GO:0008009 chemokine activity 3/1939 45/18639 0.0666666666666667 0.640845796802475 0.860731256232471 0.999999999881418 GO:0004706 JUN kinase kinase kinase activity 1/1939 18/18639 0.0555555555555556 0.534038164002063 0.861683070905995 0.999999999881418 GO:0034185 apolipoprotein binding 1/1939 18/18639 0.0555555555555556 0.534038164002063 0.861683070905995 0.999999999881418 GO:0070064 proline-rich region binding 1/1939 18/18639 0.0555555555555556 0.534038164002063 0.861683070905995 0.999999999881418 GO:0099602 neurotransmitter receptor regulator activity 1/1939 18/18639 0.0555555555555556 0.534038164002063 0.861683070905995 0.999999999881418 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 23/1939 268/18639 0.0858208955223881 0.824969402600202 0.862205957320738 0.999999999881418 GO:0042578 phosphoric ester hydrolase activity 32/1939 363/18639 0.0881542699724518 0.847399400730546 0.86267652546846 0.999999999881418 GO:0051213 dioxygenase activity 7/1939 93/18639 0.0752688172043011 0.723535577035053 0.862798724633349 0.999999999881418 GO:0008028 monocarboxylic acid transmembrane transporter activity 5/1939 70/18639 0.0714285714285714 0.686620496574081 0.865918694544487 0.999999999881418 GO:0016278 lysine N-methyltransferase activity 5/1939 70/18639 0.0714285714285714 0.686620496574081 0.865918694544487 0.999999999881418 GO:0016782 transferase activity, transferring sulphur-containing groups 5/1939 70/18639 0.0714285714285714 0.686620496574081 0.865918694544487 0.999999999881418 GO:0008514 organic anion transmembrane transporter activity 23/1939 269/18639 0.0855018587360595 0.821902601847041 0.866589244095566 0.999999999881418 GO:0140767 enzyme-substrate adaptor activity 11/1939 139/18639 0.079136690647482 0.760716233614449 0.867702422137376 0.999999999881418 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 3/1939 46/18639 0.0652173913043478 0.626914366437204 0.870632667192997 0.999999999881418 GO:0030276 clathrin binding 3/1939 46/18639 0.0652173913043478 0.626914366437204 0.870632667192997 0.999999999881418 GO:0019956 chemokine binding 2/1939 33/18639 0.0606060606060606 0.582587088002251 0.871466866907536 0.999999999881418 GO:0035591 signaling adaptor activity 10/1939 129/18639 0.0775193798449612 0.745169531165669 0.874775192676673 0.999999999881418 GO:0001786 phosphatidylserine binding 4/1939 59/18639 0.0677966101694915 0.651707589968619 0.875054755945956 0.999999999881418 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/1939 19/18639 0.0526315789473684 0.505930892212481 0.876085977598078 0.999999999881418 GO:0008381 mechanosensitive monoatomic ion channel activity 1/1939 19/18639 0.0526315789473684 0.505930892212481 0.876085977598078 0.999999999881418 GO:0016918 retinal binding 1/1939 19/18639 0.0526315789473684 0.505930892212481 0.876085977598078 0.999999999881418 GO:0022821 solute:potassium antiporter activity 1/1939 19/18639 0.0526315789473684 0.505930892212481 0.876085977598078 0.999999999881418 GO:0042577 lipid phosphatase activity 1/1939 19/18639 0.0526315789473684 0.505930892212481 0.876085977598078 0.999999999881418 GO:0043395 heparan sulfate proteoglycan binding 1/1939 19/18639 0.0526315789473684 0.505930892212481 0.876085977598078 0.999999999881418 GO:0046527 glucosyltransferase activity 1/1939 19/18639 0.0526315789473684 0.505930892212481 0.876085977598078 0.999999999881418 GO:0140036 ubiquitin-modified protein reader activity 1/1939 19/18639 0.0526315789473684 0.505930892212481 0.876085977598078 0.999999999881418 GO:0004867 serine-type endopeptidase inhibitor activity 7/1939 95/18639 0.0736842105263158 0.708303249097473 0.876703625196876 0.999999999881418 GO:0061733 protein-lysine-acetyltransferase activity 3/1939 47/18639 0.0638297872340425 0.613575762895987 0.879906292786448 0.999999999881418 GO:0015020 glucuronosyltransferase activity 2/1939 34/18639 0.0588235294117647 0.565452173649243 0.882088133346698 0.999999999881418 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/1939 34/18639 0.0588235294117647 0.565452173649243 0.882088133346698 0.999999999881418 GO:0019825 oxygen binding 2/1939 34/18639 0.0588235294117647 0.565452173649243 0.882088133346698 0.999999999881418 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/1939 60/18639 0.0666666666666667 0.640845796802475 0.883163029676535 0.999999999881418 GO:0004896 cytokine receptor activity 7/1939 96/18639 0.0729166666666667 0.700925090252708 0.883205189119324 0.999999999881418 GO:0005085 guanyl-nucleotide exchange factor activity 19/1939 230/18639 0.0826086956521739 0.794091530820459 0.883556898671273 0.999999999881418 GO:0032266 phosphatidylinositol-3-phosphate binding 3/1939 48/18639 0.0625 0.600792934502321 0.888583490709774 0.999999999881418 GO:0015095 magnesium ion transmembrane transporter activity 1/1939 20/18639 0.05 0.480634347601857 0.888989806246699 0.999999999881418 GO:0015464 acetylcholine receptor activity 1/1939 20/18639 0.05 0.480634347601857 0.888989806246699 0.999999999881418 GO:0016408 C-acyltransferase activity 1/1939 20/18639 0.05 0.480634347601857 0.888989806246699 0.999999999881418 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/1939 20/18639 0.05 0.480634347601857 0.888989806246699 0.999999999881418 GO:0030627 pre-mRNA 5'-splice site binding 1/1939 20/18639 0.05 0.480634347601857 0.888989806246699 0.999999999881418 GO:0052745 inositol phosphate phosphatase activity 1/1939 20/18639 0.05 0.480634347601857 0.888989806246699 0.999999999881418 GO:0005179 hormone activity 10/1939 132/18639 0.0757575757575758 0.728233860002813 0.891318739085878 0.999999999881418 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/1939 86/18639 0.0697674418604651 0.670652578049102 0.894668741138644 0.999999999881418 GO:0015179 L-amino acid transmembrane transporter activity 4/1939 62/18639 0.0645161290322581 0.620173351744331 0.898013149051966 0.999999999881418 GO:0005248 voltage-gated sodium channel activity 1/1939 21/18639 0.0476190476190476 0.457746997716054 0.900550511208708 0.999999999881418 GO:0008373 sialyltransferase activity 1/1939 21/18639 0.0476190476190476 0.457746997716054 0.900550511208708 0.999999999881418 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/1939 21/18639 0.0476190476190476 0.457746997716054 0.900550511208708 0.999999999881418 GO:0009975 cyclase activity 1/1939 21/18639 0.0476190476190476 0.457746997716054 0.900550511208708 0.999999999881418 GO:0015125 bile acid transmembrane transporter activity 1/1939 21/18639 0.0476190476190476 0.457746997716054 0.900550511208708 0.999999999881418 GO:0019200 carbohydrate kinase activity 1/1939 21/18639 0.0476190476190476 0.457746997716054 0.900550511208708 0.999999999881418 GO:0035613 RNA stem-loop binding 1/1939 21/18639 0.0476190476190476 0.457746997716054 0.900550511208708 0.999999999881418 GO:0036122 BMP binding 1/1939 21/18639 0.0476190476190476 0.457746997716054 0.900550511208708 0.999999999881418 GO:0008081 phosphoric diester hydrolase activity 6/1939 87/18639 0.0689655172413793 0.662943927726699 0.90069692050966 0.999999999881418 GO:0000993 RNA polymerase II complex binding 2/1939 36/18639 0.0555555555555556 0.534038164002063 0.900933340778625 0.999999999881418 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 2/1939 36/18639 0.0555555555555556 0.534038164002063 0.900933340778625 0.999999999881418 GO:0005006 epidermal growth factor receptor activity 3/1939 50/18639 0.06 0.576761217122228 0.904271097141916 0.999999999881418 GO:0030414 peptidase inhibitor activity 13/1939 169/18639 0.0769230769230769 0.73943745784901 0.905396388792661 0.999999999881418 GO:0008093 cytoskeletal anchor activity 1/1939 22/18639 0.0454545454545455 0.436940316001688 0.910907829866261 0.999999999881418 GO:0031683 G-protein beta/gamma-subunit complex binding 1/1939 22/18639 0.0454545454545455 0.436940316001688 0.910907829866261 0.999999999881418 GO:0033691 sialic acid binding 1/1939 22/18639 0.0454545454545455 0.436940316001688 0.910907829866261 0.999999999881418 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 42/1939 484/18639 0.0867768595041322 0.834158785094131 0.911793665394105 0.999999999881418 GO:0003724 RNA helicase activity 5/1939 77/18639 0.0649350649350649 0.624200451430983 0.913504456297892 0.999999999881418 GO:0000146 microfilament motor activity 2/1939 38/18639 0.0526315789473684 0.505930892212481 0.916935940455959 0.999999999881418 GO:0005543 phospholipid binding 43/1939 497/18639 0.0865191146881288 0.83168116486438 0.917580825379797 0.999999999881418 GO:0030159 signaling receptor complex adaptor activity 3/1939 52/18639 0.0576923076923077 0.554578093386758 0.917932872060877 0.999999999881418 GO:0004866 endopeptidase inhibitor activity 12/1939 161/18639 0.0745341614906832 0.716473561642519 0.918753068332515 0.999999999881418 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/1939 23/18639 0.0434782608695652 0.417942910958136 0.92018696817476 0.999999999881418 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/1939 23/18639 0.0434782608695652 0.417942910958136 0.92018696817476 0.999999999881418 GO:0016493 C-C chemokine receptor activity 1/1939 23/18639 0.0434782608695652 0.417942910958136 0.92018696817476 0.999999999881418 GO:0016849 phosphorus-oxygen lyase activity 1/1939 23/18639 0.0434782608695652 0.417942910958136 0.92018696817476 0.999999999881418 GO:0140103 catalytic activity, acting on a glycoprotein 1/1939 23/18639 0.0434782608695652 0.417942910958136 0.92018696817476 0.999999999881418 GO:0035091 phosphatidylinositol binding 23/1939 284/18639 0.0809859154929577 0.778492253157937 0.920208139539752 0.999999999881418 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 6/1939 91/18639 0.0659340659340659 0.633803535299152 0.921931052991399 0.999999999881418 GO:0070851 growth factor receptor binding 10/1939 139/18639 0.0719424460431655 0.691560212376772 0.92298741093544 0.999999999881418 GO:0008186 ATP-dependent activity, acting on RNA 5/1939 79/18639 0.0632911392405063 0.608397908356781 0.924042137078523 0.999999999881418 GO:0046332 SMAD binding 5/1939 79/18639 0.0632911392405063 0.608397908356781 0.924042137078523 0.999999999881418 GO:0005003 ephrin receptor activity 3/1939 53/18639 0.0566037735849057 0.544114355775687 0.9240744448778 0.999999999881418 GO:0005005 transmembrane-ephrin receptor activity 3/1939 53/18639 0.0566037735849057 0.544114355775687 0.9240744448778 0.999999999881418 GO:0017046 peptide hormone binding 3/1939 53/18639 0.0566037735849057 0.544114355775687 0.9240744448778 0.999999999881418 GO:0015149 hexose transmembrane transporter activity 1/1939 24/18639 0.0416666666666667 0.400528623001547 0.928500111100691 0.999999999881418 GO:0019957 C-C chemokine binding 1/1939 24/18639 0.0416666666666667 0.400528623001547 0.928500111100691 0.999999999881418 GO:0050431 transforming growth factor beta binding 1/1939 24/18639 0.0416666666666667 0.400528623001547 0.928500111100691 0.999999999881418 GO:0055056 D-glucose transmembrane transporter activity 1/1939 24/18639 0.0416666666666667 0.400528623001547 0.928500111100691 0.999999999881418 GO:0070840 dynein complex binding 1/1939 24/18639 0.0416666666666667 0.400528623001547 0.928500111100691 0.999999999881418 GO:0071855 neuropeptide receptor binding 2/1939 40/18639 0.05 0.480634347601857 0.930483511430894 0.999999999881418 GO:0140223 general transcription initiation factor activity 4/1939 68/18639 0.0588235294117647 0.565452173649243 0.933040864996332 0.999999999881418 GO:0016757 glycosyltransferase activity 21/1939 267/18639 0.0786516853932584 0.756054029935505 0.933793462563153 0.999999999881418 GO:0003707 nuclear steroid receptor activity 1/1939 25/18639 0.04 0.384507478081485 0.935947776132964 0.999999999881418 GO:0004709 MAP kinase kinase kinase activity 1/1939 25/18639 0.04 0.384507478081485 0.935947776132964 0.999999999881418 GO:0005251 delayed rectifier potassium channel activity 1/1939 25/18639 0.04 0.384507478081485 0.935947776132964 0.999999999881418 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/1939 25/18639 0.04 0.384507478081485 0.935947776132964 0.999999999881418 GO:0140828 metal cation:monoatomic cation antiporter activity 2/1939 41/18639 0.0487804878048781 0.468911558635958 0.936446199581463 0.999999999881418 GO:0005319 lipid transporter activity 13/1939 178/18639 0.0730337078651685 0.702050170654397 0.937242892046661 0.999999999881418 GO:0030246 carbohydrate binding 22/1939 280/18639 0.0785714285714286 0.755282546231489 0.93850077402353 0.999999999881418 GO:0004674 protein serine/threonine kinase activity 36/1939 433/18639 0.0831408775981524 0.799207229268676 0.939454526472796 0.999999999881418 GO:0005496 steroid binding 7/1939 108/18639 0.0648148148148148 0.623044524669073 0.94118094126238 0.999999999881418 GO:0004402 histone acetyltransferase activity 2/1939 42/18639 0.0476190476190476 0.457746997716054 0.941921409601818 0.999999999881418 GO:0043175 RNA polymerase core enzyme binding 2/1939 42/18639 0.0476190476190476 0.457746997716054 0.941921409601818 0.999999999881418 GO:0005112 Notch binding 1/1939 26/18639 0.0384615384615385 0.369718728924505 0.942620026164026 0.999999999881418 GO:0015145 monosaccharide transmembrane transporter activity 1/1939 26/18639 0.0384615384615385 0.369718728924505 0.942620026164026 0.999999999881418 GO:0030507 spectrin binding 1/1939 26/18639 0.0384615384615385 0.369718728924505 0.942620026164026 0.999999999881418 GO:0043548 phosphatidylinositol 3-kinase binding 1/1939 26/18639 0.0384615384615385 0.369718728924505 0.942620026164026 0.999999999881418 GO:0052742 phosphatidylinositol kinase activity 1/1939 26/18639 0.0384615384615385 0.369718728924505 0.942620026164026 0.999999999881418 GO:0005385 zinc ion transmembrane transporter activity 1/1939 27/18639 0.037037037037037 0.356025442668042 0.948597556345509 0.999999999881418 GO:0008395 steroid hydroxylase activity 1/1939 27/18639 0.037037037037037 0.356025442668042 0.948597556345509 0.999999999881418 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/1939 44/18639 0.0454545454545455 0.436940316001688 0.951554337999253 0.999999999881418 GO:0019838 growth factor binding 9/1939 136/18639 0.0661764705882353 0.636133695355398 0.952036333837254 0.999999999881418 GO:0005516 calmodulin binding 15/1939 207/18639 0.072463768115942 0.69657151826356 0.952349460517365 0.999999999881418 GO:0004879 nuclear receptor activity 3/1939 59/18639 0.0508474576271186 0.488780692476464 0.952870730075174 0.999999999881418 GO:0050698 proteoglycan sulfotransferase activity 1/1939 28/18639 0.0357142857142857 0.34331024828704 0.953952668007129 0.999999999881418 GO:0051119 sugar transmembrane transporter activity 1/1939 28/18639 0.0357142857142857 0.34331024828704 0.953952668007129 0.999999999881418 GO:0051959 dynein light intermediate chain binding 1/1939 28/18639 0.0357142857142857 0.34331024828704 0.953952668007129 0.999999999881418 GO:0003779 actin binding 36/1939 443/18639 0.0812641083521445 0.781166434025591 0.956141857247373 0.999999999881418 GO:0098531 ligand-modulated transcription factor activity 3/1939 60/18639 0.05 0.480634347601857 0.956539556411944 0.999999999881418 GO:0004181 metallocarboxypeptidase activity 1/1939 29/18639 0.0344827586206897 0.331471963863349 0.958750141368806 0.999999999881418 GO:0035250 UDP-galactosyltransferase activity 1/1939 29/18639 0.0344827586206897 0.331471963863349 0.958750141368806 0.999999999881418 GO:0019905 syntaxin binding 3/1939 61/18639 0.0491803278688525 0.472755096001826 0.959939405892886 0.999999999881418 GO:0017124 SH3 domain binding 7/1939 115/18639 0.0608695652173913 0.585120075341391 0.961656955630646 0.999999999881418 GO:0051020 GTPase binding 24/1939 315/18639 0.0761904761904762 0.732395196345686 0.962524973580226 0.999999999881418 GO:0017022 myosin binding 4/1939 76/18639 0.0526315789473684 0.505930892212481 0.962796235078347 0.999999999881418 GO:0001968 fibronectin binding 1/1939 30/18639 0.0333333333333333 0.320422898401238 0.963048017558268 0.999999999881418 GO:0140359 ABC-type transporter activity 2/1939 47/18639 0.0425531914893617 0.409050508597325 0.963193057778953 0.999999999881418 GO:0140938 histone H3 methyltransferase activity 2/1939 47/18639 0.0425531914893617 0.409050508597325 0.963193057778953 0.999999999881418 GO:0106310 protein serine kinase activity 28/1939 361/18639 0.0775623268698061 0.745582367471024 0.9643598265257 0.999999999881418 GO:0005184 neuropeptide hormone activity 1/1939 31/18639 0.032258064516129 0.310086675872166 0.966898299354953 0.999999999881418 GO:0005452 solute:inorganic anion antiporter activity 1/1939 31/18639 0.032258064516129 0.310086675872166 0.966898299354953 0.999999999881418 GO:0017147 Wnt-protein binding 1/1939 31/18639 0.032258064516129 0.310086675872166 0.966898299354953 0.999999999881418 GO:0019199 transmembrane receptor protein kinase activity 4/1939 78/18639 0.0512820512820513 0.492958305232673 0.968014598099954 0.999999999881418 GO:0005004 GPI-linked ephrin receptor activity 2/1939 49/18639 0.0408163265306122 0.392354569470903 0.969404692153457 0.999999999881418 GO:0005008 hepatocyte growth factor receptor activity 2/1939 49/18639 0.0408163265306122 0.392354569470903 0.969404692153457 0.999999999881418 GO:0005009 insulin receptor activity 2/1939 49/18639 0.0408163265306122 0.392354569470903 0.969404692153457 0.999999999881418 GO:0005011 macrophage colony-stimulating factor receptor activity 2/1939 49/18639 0.0408163265306122 0.392354569470903 0.969404692153457 0.999999999881418 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/1939 49/18639 0.0408163265306122 0.392354569470903 0.969404692153457 0.999999999881418 GO:0005020 stem cell factor receptor activity 2/1939 49/18639 0.0408163265306122 0.392354569470903 0.969404692153457 0.999999999881418 GO:0008288 boss receptor activity 2/1939 49/18639 0.0408163265306122 0.392354569470903 0.969404692153457 0.999999999881418 GO:0036332 placental growth factor receptor activity 2/1939 49/18639 0.0408163265306122 0.392354569470903 0.969404692153457 0.999999999881418 GO:0038062 protein tyrosine kinase collagen receptor activity 2/1939 49/18639 0.0408163265306122 0.392354569470903 0.969404692153457 0.999999999881418 GO:0060175 brain-derived neurotrophic factor receptor activity 2/1939 49/18639 0.0408163265306122 0.392354569470903 0.969404692153457 0.999999999881418 GO:0005126 cytokine receptor binding 20/1939 275/18639 0.0727272727272727 0.699104505602701 0.970123462319989 0.999999999881418 GO:0004497 monooxygenase activity 6/1939 106/18639 0.0566037735849057 0.544114355775687 0.970230775147195 0.999999999881418 GO:0008378 galactosyltransferase activity 1/1939 32/18639 0.03125 0.30039646725116 0.970347579102951 0.999999999881418 GO:0160041 neuropeptide activity 1/1939 32/18639 0.03125 0.30039646725116 0.970347579102951 0.999999999881418 GO:0015370 solute:sodium symporter activity 4/1939 79/18639 0.0506329113924051 0.486718326685424 0.970359796021097 0.999999999881418 GO:0015291 secondary active transmembrane transporter activity 21/1939 287/18639 0.0731707317073171 0.703367337953936 0.970797356643167 0.999999999881418 GO:0005007 fibroblast growth factor receptor activity 2/1939 50/18639 0.04 0.384507478081485 0.972118591945605 0.999999999881418 GO:0005017 platelet-derived growth factor receptor activity 2/1939 50/18639 0.04 0.384507478081485 0.972118591945605 0.999999999881418 GO:0005019 platelet-derived growth factor beta-receptor activity 2/1939 50/18639 0.04 0.384507478081485 0.972118591945605 0.999999999881418 GO:0048020 CCR chemokine receptor binding 2/1939 50/18639 0.04 0.384507478081485 0.972118591945605 0.999999999881418 GO:0030296 protein tyrosine kinase activator activity 1/1939 33/18639 0.0303030303030303 0.291293544001125 0.973437601359058 0.999999999881418 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 17/1939 243/18639 0.0699588477366255 0.672492502817413 0.973713035809363 0.999999999881418 GO:0004843 cysteine-type deubiquitinase activity 6/1939 108/18639 0.0555555555555556 0.534038164002063 0.973993834502126 0.999999999881418 GO:0015101 organic cation transmembrane transporter activity 4/1939 81/18639 0.0493827160493827 0.474700590224056 0.974575569437524 0.999999999881418 GO:0005010 insulin-like growth factor receptor activity 2/1939 51/18639 0.0392156862745098 0.376968115766162 0.974599313995338 0.999999999881418 GO:0005021 vascular endothelial growth factor receptor activity 2/1939 51/18639 0.0392156862745098 0.376968115766162 0.974599313995338 0.999999999881418 GO:0005030 neurotrophin receptor activity 2/1939 51/18639 0.0392156862745098 0.376968115766162 0.974599313995338 0.999999999881418 GO:0005272 sodium channel activity 2/1939 51/18639 0.0392156862745098 0.376968115766162 0.974599313995338 0.999999999881418 GO:0016500 protein-hormone receptor activity 3/1939 67/18639 0.0447761194029851 0.430418818747931 0.975625806913419 0.999999999881418 GO:0004676 3-phosphoinositide-dependent protein kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0004711 ribosomal protein S6 kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0035175 histone H3S10 kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0035979 histone H2AXS139 kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0044022 histone H3S28 kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0044023 histone H4S1 kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0044024 histone H2AS1 kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0044025 histone H2BS14 kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0072354 histone H3T3 kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0072371 histone H2AS121 kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0072518 Rho-dependent protein serine/threonine kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0140823 histone H2BS36 kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0140855 histone H3S57 kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0140995 histone H2A kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0140997 histone H4 kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0140998 histone H2B kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:1990244 histone H2AT120 kinase activity 17/1939 245/18639 0.0693877551020408 0.667002768100536 0.976096859619235 0.999999999881418 GO:0008376 acetylgalactosaminyltransferase activity 1/1939 34/18639 0.0294117647058824 0.282726086824622 0.976205767056402 0.999999999881418 GO:0004677 DNA-dependent protein kinase activity 17/1939 246/18639 0.0691056910569106 0.664291374734273 0.977214522044298 0.999999999881418 GO:0140857 histone H3T45 kinase activity 17/1939 246/18639 0.0691056910569106 0.664291374734273 0.977214522044298 0.999999999881418 GO:0016755 aminoacyltransferase activity 39/1939 496/18639 0.0786290322580645 0.755836272438403 0.977939339198916 0.999999999881418 GO:0008083 growth factor activity 10/1939 162/18639 0.0617283950617284 0.59337573778007 0.978011945606226 0.999999999881418 GO:0030165 PDZ domain binding 4/1939 83/18639 0.0481927710843374 0.463262021784922 0.978223316493453 0.999999999881418 GO:0035402 histone H3T11 kinase activity 17/1939 247/18639 0.0688259109311741 0.661601935970167 0.97828501870763 0.999999999881418 GO:0035403 histone H3T6 kinase activity 17/1939 247/18639 0.0688259109311741 0.661601935970167 0.97828501870763 0.999999999881418 GO:0005343 organic acid:sodium symporter activity 1/1939 35/18639 0.0285714285714286 0.274648198629632 0.978685585259984 0.999999999881418 GO:0005246 calcium channel regulator activity 2/1939 53/18639 0.0377358490566038 0.362742903850458 0.978936227625458 0.999999999881418 GO:0008146 sulfotransferase activity 2/1939 53/18639 0.0377358490566038 0.362742903850458 0.978936227625458 0.999999999881418 GO:0038064 collagen receptor activity 2/1939 53/18639 0.0377358490566038 0.362742903850458 0.978936227625458 0.999999999881418 GO:0051018 protein kinase A binding 2/1939 53/18639 0.0377358490566038 0.362742903850458 0.978936227625458 0.999999999881418 GO:0004679 AMP-activated protein kinase activity 17/1939 248/18639 0.0685483870967742 0.658934186228352 0.979310044827385 0.999999999881418 GO:0004190 aspartic-type endopeptidase activity 1/1939 36/18639 0.0277777777777778 0.267019082001031 0.980907077959451 0.999999999881418 GO:0019787 ubiquitin-like protein transferase activity 37/1939 479/18639 0.0772442588726514 0.742524879384914 0.981646336402233 0.999999999881418 GO:0004713 protein tyrosine kinase activity 8/1939 140/18639 0.0571428571428571 0.549296397259265 0.982195674534488 0.999999999881418 GO:0030280 structural constituent of skin epidermis 1/1939 37/18639 0.027027027027027 0.259802350055058 0.982897142778922 0.999999999881418 GO:0030551 cyclic nucleotide binding 1/1939 37/18639 0.027027027027027 0.259802350055058 0.982897142778922 0.999999999881418 GO:0070001 aspartic-type peptidase activity 1/1939 37/18639 0.027027027027027 0.259802350055058 0.982897142778922 0.999999999881418 GO:0035401 histone H3Y41 kinase activity 6/1939 115/18639 0.0521739130434783 0.501531493149763 0.983968369088516 0.999999999881418 GO:0140801 histone H2AXY142 kinase activity 6/1939 115/18639 0.0521739130434783 0.501531493149763 0.983968369088516 0.999999999881418 GO:0042379 chemokine receptor binding 3/1939 72/18639 0.0416666666666667 0.400528623001547 0.984043534210384 0.999999999881418 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/1939 56/18639 0.0357142857142857 0.34331024828704 0.984125413394126 0.999999999881418 GO:0005109 frizzled binding 1/1939 38/18639 0.0263157894736842 0.25296544610624 0.98467987797684 0.999999999881418 GO:0005501 retinoid binding 1/1939 38/18639 0.0263157894736842 0.25296544610624 0.98467987797684 0.999999999881418 GO:0019840 isoprenoid binding 1/1939 38/18639 0.0263157894736842 0.25296544610624 0.98467987797684 0.999999999881418 GO:0015294 solute:monoatomic cation symporter activity 6/1939 116/18639 0.0517241379310345 0.497207945795024 0.98505836141497 0.999999999881418 GO:0015144 carbohydrate transmembrane transporter activity 1/1939 40/18639 0.025 0.240317173800928 0.987707472686027 0.999999999881418 GO:0000149 SNARE binding 5/1939 106/18639 0.0471698113207547 0.453428629813072 0.988822429520304 0.999999999881418 GO:0008013 beta-catenin binding 5/1939 106/18639 0.0471698113207547 0.453428629813072 0.988822429520304 0.999999999881418 GO:0001727 lipid kinase activity 1/1939 41/18639 0.024390243902439 0.234455779317979 0.988989004513641 0.999999999881418 GO:0004812 aminoacyl-tRNA ligase activity 1/1939 41/18639 0.024390243902439 0.234455779317979 0.988989004513641 0.999999999881418 GO:0008227 G protein-coupled amine receptor activity 1/1939 41/18639 0.024390243902439 0.234455779317979 0.988989004513641 0.999999999881418 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/1939 41/18639 0.024390243902439 0.234455779317979 0.988989004513641 0.999999999881418 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/1939 41/18639 0.024390243902439 0.234455779317979 0.988989004513641 0.999999999881418 GO:0004842 ubiquitin-protein transferase activity 33/1939 449/18639 0.0734966592427617 0.706500377321215 0.9896906322747 0.999999999881418 GO:0008307 structural constituent of muscle 1/1939 42/18639 0.0238095238095238 0.228873498858027 0.990136994633441 0.999999999881418 GO:0004175 endopeptidase activity 29/1939 405/18639 0.0716049382716049 0.688315855824881 0.990441855500528 0.999999999881418 GO:0042562 hormone binding 4/1939 94/18639 0.0425531914893617 0.409050508597325 0.990924632425848 0.999999999881418 GO:0005245 voltage-gated calcium channel activity 1/1939 43/18639 0.0232558139534884 0.223550859349701 0.991165352293588 0.999999999881418 GO:0030547 signaling receptor inhibitor activity 1/1939 44/18639 0.0227272727272727 0.218470158000844 0.992086538672527 0.999999999881418 GO:0005261 monoatomic cation channel activity 23/1939 341/18639 0.0674486803519062 0.648363049550892 0.9927598199698 0.999999999881418 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/1939 45/18639 0.0222222222222222 0.213615265600825 0.992911717565453 0.999999999881418 GO:0005201 extracellular matrix structural constituent 9/1939 168/18639 0.0535714285714286 0.514965372430561 0.993169551685111 0.999999999881418 GO:0001664 G protein-coupled receptor binding 19/1939 297/18639 0.063973063973064 0.614953037335709 0.994088334852836 0.999999999881418 GO:0016758 hexosyltransferase activity 11/1939 197/18639 0.0558375634517767 0.536749017626439 0.994229125144865 0.999999999881418 GO:0008194 UDP-glycosyltransferase activity 7/1939 145/18639 0.0482758620689655 0.464060749408689 0.994910068435785 0.999999999881418 GO:0015171 amino acid transmembrane transporter activity 4/1939 102/18639 0.0392156862745098 0.376968115766162 0.995302163947911 0.999999999881418 GO:0098960 postsynaptic neurotransmitter receptor activity 2/1939 69/18639 0.0289855072463768 0.278628607305424 0.995447152978495 0.999999999881418 GO:0005253 monoatomic anion channel activity 4/1939 103/18639 0.0388349514563107 0.373308231147073 0.995678311414426 0.999999999881418 GO:0031267 small GTPase binding 17/1939 283/18639 0.0600706713780919 0.577440558956294 0.996676383552065 0.999999999881418 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/1939 73/18639 0.0273972602739726 0.263361286357182 0.996919504399958 0.999999999881418 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/1939 53/18639 0.0188679245283019 0.181371451925229 0.997063436900797 0.999999999881418 GO:0061659 ubiquitin-like protein ligase activity 24/1939 372/18639 0.0645161290322581 0.620173351744331 0.997142020193853 0.999999999881418 GO:0035173 histone kinase activity 23/1939 360/18639 0.0638888888888889 0.614143888602372 0.997161171986301 0.999999999881418 GO:0061630 ubiquitin protein ligase activity 22/1939 353/18639 0.0623229461756374 0.599090971515062 0.997833685629009 0.999999999881418 GO:0141003 histone H2AX kinase activity 22/1939 354/18639 0.0621468926553672 0.597398624137901 0.997944633368555 0.999999999881418 GO:0140996 histone H3 kinase activity 22/1939 357/18639 0.061624649859944 0.59237846763254 0.998246220399146 0.999999999881418 GO:0003823 antigen binding 8/1939 174/18639 0.0459770114942529 0.441962618484466 0.998252473521442 0.999999999881418 GO:0015293 symporter activity 6/1939 146/18639 0.0410958904109589 0.395041929535773 0.99840882566488 0.999999999881418 GO:0005249 voltage-gated potassium channel activity 3/1939 98/18639 0.0306122448979592 0.294265927103178 0.998416200631072 0.999999999881418 GO:0005262 calcium channel activity 5/1939 131/18639 0.0381679389312977 0.366896448551036 0.998447860557208 0.999999999881418 GO:0004252 serine-type endopeptidase activity 8/1939 176/18639 0.0454545454545455 0.436940316001688 0.998488376349319 0.999999999881418 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/1939 60/18639 0.0166666666666667 0.160211449200619 0.998642210348342 0.999999999881418 GO:0005125 cytokine activity 12/1939 234/18639 0.0512820512820513 0.492958305232673 0.998728363524631 0.999999999881418 GO:0015081 sodium ion transmembrane transporter activity 7/1939 164/18639 0.0426829268292683 0.410297613806463 0.998747369278268 0.999999999881418 GO:0015103 inorganic anion transmembrane transporter activity 7/1939 165/18639 0.0424242424242424 0.407810961601575 0.998838987663297 0.999999999881418 GO:0008236 serine-type peptidase activity 9/1939 194/18639 0.0463917525773196 0.445949394682135 0.998846377946793 0.999999999881418 GO:0005254 chloride channel activity 2/1939 83/18639 0.0240963855421687 0.231631010892461 0.998852085282624 0.999999999881418 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 8/1939 181/18639 0.0441988950276243 0.424870141526503 0.998951796776424 0.999999999881418 GO:0030695 GTPase regulator activity 32/1939 489/18639 0.065439672801636 0.629051088885866 0.998962523979606 0.999999999881418 GO:0099094 ligand-gated monoatomic cation channel activity 5/1939 136/18639 0.0367647058823529 0.353407608530777 0.998971921834275 0.999999999881418 GO:0060589 nucleoside-triphosphatase regulator activity 32/1939 490/18639 0.0653061224489796 0.627767311153445 0.999011395127524 0.999999999881418 GO:0022824 transmitter-gated monoatomic ion channel activity 1/1939 63/18639 0.0158730158730159 0.152582332572018 0.999024522439109 0.999999999881418 GO:0022835 transmitter-gated channel activity 1/1939 63/18639 0.0158730158730159 0.152582332572018 0.999024522439109 0.999999999881418 GO:0017171 serine hydrolase activity 9/1939 198/18639 0.0454545454545455 0.436940316001688 0.9991335059692 0.999999999881418 GO:0005216 monoatomic ion channel activity 28/1939 448/18639 0.0625 0.600792934502321 0.99928459088939 0.999999999881418 GO:0005096 GTPase activator activity 14/1939 271/18639 0.0516605166051661 0.496596373905977 0.999337541268563 0.999999999881418 GO:0022832 voltage-gated channel activity 7/1939 175/18639 0.04 0.384507478081485 0.999462548038795 0.999999999881418 GO:0015085 calcium ion transmembrane transporter activity 5/1939 147/18639 0.0340136054421769 0.326962141225753 0.999591476025253 0.999999999881418 GO:0008509 monoatomic anion transmembrane transporter activity 5/1939 149/18639 0.0335570469798658 0.322573387652253 0.99965536905199 0.999999999881418 GO:0030594 neurotransmitter receptor activity 2/1939 97/18639 0.0206185567010309 0.198199730969838 0.999717681107473 0.999999999881418 GO:0005244 voltage-gated monoatomic ion channel activity 6/1939 173/18639 0.0346820809248555 0.333387986775854 0.999820423652665 0.999999999881418 GO:0005267 potassium channel activity 3/1939 124/18639 0.0241935483870968 0.232565006904124 0.999861292079713 0.999999999881418 GO:0022843 voltage-gated monoatomic cation channel activity 4/1939 143/18639 0.027972027972028 0.268886348308731 0.999869659505733 0.999999999881418 GO:0015276 ligand-gated monoatomic ion channel activity 6/1939 186/18639 0.032258064516129 0.310086675872166 0.99993981326327 0.999999999881418 GO:0022834 ligand-gated channel activity 6/1939 188/18639 0.0319148936170213 0.306787881447994 0.999949238075811 0.999999999881418 GO:0015079 potassium ion transmembrane transporter activity 4/1939 160/18639 0.025 0.240317173800928 0.999972660957233 0.999999999881418 GO:0015108 chloride transmembrane transporter activity 2/1939 121/18639 0.0165289256198347 0.158887387636977 0.999975551065867 0.999999999881418 GO:0001653 peptide receptor activity 2/1939 128/18639 0.015625 0.15019823362558 0.999988115575895 0.999999999881418 GO:0022836 gated channel activity 13/1939 318/18639 0.0408805031446541 0.392971479171329 0.999990497549651 0.999999999881418 GO:0008528 G protein-coupled peptide receptor activity 1/1939 122/18639 0.00819672131147541 0.0787925160003044 0.999998555256323 0.999999999881418 GO:0046873 metal ion transmembrane transporter activity 18/1939 450/18639 0.04 0.384507478081485 0.999999870181363 0.999999999881418 GO:0045182 translation regulator activity 11/1939 356/18639 0.0308988764044944 0.297021226046091 0.999999961040298 0.999999999881418 GO:0030371 translation repressor activity 6/1939 329/18639 0.0182370820668693 0.175307360827425 0.999999999881418 0.999999999881418