ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0042605 peptide antigen binding 19/1271 45/18639 0.422222222222222 6.19181746656176 2.68530937155493e-11 3.04514082734329e-08 GO:0023026 MHC class II protein complex binding 12/1271 27/18639 0.444444444444444 6.5177025963808 6.38503706803569e-08 2.62787851774116e-05 GO:0140297 DNA-binding transcription factor binding 66/1271 488/18639 0.135245901639344 1.98335826959539 6.95205957074381e-08 2.62787851774116e-05 GO:0023023 MHC protein complex binding 13/1271 37/18639 0.351351351351351 5.15250813362536 4.92787987664299e-07 0.000114646282932552 GO:0051082 unfolded protein binding 25/1271 121/18639 0.206611570247934 3.02992372765637 5.05495074658519e-07 0.000114646282932552 GO:0031072 heat shock protein binding 26/1271 131/18639 0.198473282442748 2.91057711365097 6.83762863085393e-07 0.000129231181123139 GO:0042277 peptide binding 39/1271 249/18639 0.156626506024096 2.29690121619444 9.29754330940154e-07 0.000150620201612305 GO:0044183 protein folding chaperone 18/1271 75/18639 0.24 3.51955940204563 2.06856974703499e-06 0.00029321976164221 GO:0060590 ATPase regulator activity 14/1271 49/18639 0.285714285714286 4.18995166910194 3.07858743322546e-06 0.000387902016586407 GO:0044389 ubiquitin-like protein ligase binding 45/1271 322/18639 0.139751552795031 2.04943288162595 3.49228911348056e-06 0.000396025585468695 GO:0038024 cargo receptor activity 16/1271 65/18639 0.246153846153846 3.6098045149186 5.31784010036561e-06 0.000548220970346782 GO:0140662 ATP-dependent protein folding chaperone 12/1271 40/18639 0.3 4.39944925255704 8.94316219099383e-06 0.000845128827048917 GO:0003746 translation elongation factor activity 8/1271 18/18639 0.444444444444444 6.5177025963808 1.07886252538963e-05 0.000927418790958829 GO:0180051 translation factor activity 18/1271 84/18639 0.214285714285714 3.14246375182646 1.14496147031954e-05 0.000927418790958829 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 46/1271 349/18639 0.131805157593123 1.93290034018743 1.30810278529375e-05 0.000988925705682075 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 6/1271 10/18639 0.6 8.79889850511408 1.64370953293701e-05 0.0011649791314691 GO:0031625 ubiquitin protein ligase binding 41/1271 302/18639 0.135761589403974 1.99092074343089 1.88807675695984e-05 0.00125945826023086 GO:0071813 lipoprotein particle binding 10/1271 32/18639 0.3125 4.58275963808025 3.38216169582266e-05 0.00201861650687521 GO:0071814 protein-lipid complex binding 10/1271 32/18639 0.3125 4.58275963808025 3.38216169582266e-05 0.00201861650687521 GO:0008135 translation factor activity, RNA binding 17/1271 83/18639 0.204819277108434 3.00364005194657 3.69584317985473e-05 0.00209554308297763 GO:0140311 protein sequestering activity 10/1271 33/18639 0.303030303030303 4.443888133896 4.55769580253865e-05 0.00243288705257647 GO:0001671 ATPase activator activity 9/1271 27/18639 0.333333333333333 4.8882769472856 4.71988669812013e-05 0.00243288705257647 GO:0030169 low-density lipoprotein particle binding 7/1271 17/18639 0.411764705882353 6.03845975841163 7.13976633077605e-05 0.00352021522569567 GO:0051087 protein-folding chaperone binding 22/1271 134/18639 0.164179104477612 2.40765879493171 0.000103675567860426 0.00489867058140512 GO:0035925 mRNA 3'-UTR AU-rich region binding 9/1271 30/18639 0.3 4.39944925255704 0.000119598214990652 0.00542497503197595 GO:0140104 molecular carrier activity 33/1271 249/18639 0.132530120481928 1.94353179831837 0.000188124308712941 0.007968263949888 GO:0140597 protein carrier chaperone 27/1271 188/18639 0.143617021276596 2.10611932303263 0.000189720570235428 0.007968263949888 GO:0140416 transcription regulator inhibitor activity 9/1271 33/18639 0.272727272727273 3.9994993205064 0.000267730315682754 0.0108430777851515 GO:0001221 transcription coregulator binding 18/1271 115/18639 0.156521739130435 2.29536482742107 0.000767963929345385 0.030030037788885 GO:0060229 lipase activator activity 7/1271 24/18639 0.291666666666667 4.2772423288749 0.000832787303402557 0.0314793600686166 GO:0016411 acylglycerol O-acyltransferase activity 8/1271 31/18639 0.258064516129032 3.78447247531789 0.000876589299428534 0.0320277014290643 GO:0030228 lipoprotein particle receptor activity 6/1271 18/18639 0.333333333333333 4.8882769472856 0.000903779934506224 0.0320277014290643 GO:0042826 histone deacetylase binding 19/1271 127/18639 0.149606299212598 2.19395107082897 0.000977750245866633 0.033393593628041 GO:0140313 molecular sequestering activity 11/1271 55/18639 0.2 2.93296616837136 0.00104980403545621 0.033393593628041 GO:0001216 DNA-binding transcription activator activity 52/1271 491/18639 0.105906313645621 1.55309817469767 0.00105349859613652 0.033393593628041 GO:0001618 virus receptor activity 14/1271 81/18639 0.172839506172839 2.53466212081476 0.00107301467985777 0.033393593628041 GO:0140658 ATP-dependent chromatin remodeler activity 22/1271 158/18639 0.139240506329114 2.04193847165095 0.00108956169685848 0.033393593628041 GO:0140272 exogenous protein binding 14/1271 82/18639 0.170731707317073 2.50375160714628 0.00121430016695324 0.0349926154620675 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 10/1271 48/18639 0.208333333333333 3.0551730920535 0.00126370963240273 0.0349926154620675 GO:0003689 DNA clamp loader activity 22/1271 160/18639 0.1375 2.01641424075531 0.00128756625888171 0.0349926154620675 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 14/1271 83/18639 0.168674698795181 2.47358592513247 0.0013708312716605 0.0349926154620675 GO:0003697 single-stranded DNA binding 18/1271 121/18639 0.148760330578512 2.18154508391258 0.00140270954059854 0.0349926154620675 GO:0000510 H3-H4 histone complex chaperone activity 21/1271 151/18639 0.139072847682119 2.0394797859536 0.001419453537262 0.0349926154620675 GO:0140584 chromatin extrusion motor activity 21/1271 151/18639 0.139072847682119 2.0394797859536 0.001419453537262 0.0349926154620675 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 21/1271 151/18639 0.139072847682119 2.0394797859536 0.001419453537262 0.0349926154620675 GO:0140849 ATP-dependent H2AZ histone chaperone activity 21/1271 151/18639 0.139072847682119 2.0394797859536 0.001419453537262 0.0349926154620675 GO:0008137 NADH dehydrogenase (ubiquinone) activity 9/1271 41/18639 0.219512195121951 3.21910920918808 0.00148516955357864 0.0357260443540707 GO:0015616 DNA translocase activity 21/1271 152/18639 0.138157894736842 2.02606215578285 0.00154371796591663 0.0357260443540707 GO:0140674 ATP-dependent histone chaperone activity 21/1271 152/18639 0.138157894736842 2.02606215578285 0.00154371796591663 0.0357260443540707 GO:0061775 cohesin loader activity 21/1271 153/18639 0.137254901960784 2.01281991947054 0.00167713513597612 0.0365764158741684 GO:0016004 phospholipase activator activity 6/1271 20/18639 0.3 4.39944925255704 0.00167722541927404 0.0365764158741684 GO:0042288 MHC class I protein binding 6/1271 20/18639 0.3 4.39944925255704 0.00167722541927404 0.0365764158741684 GO:0035198 miRNA binding 9/1271 42/18639 0.214285714285714 3.14246375182646 0.00177762767391848 0.0374802821537347 GO:0005044 scavenger receptor activity 7/1271 27/18639 0.259259259259259 3.80199318122213 0.00178477534065404 0.0374802821537347 GO:0004386 helicase activity 21/1271 155/18639 0.135483870967742 1.98684804954189 0.00197357598443489 0.0401753198738523 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 12/1271 68/18639 0.176470588235294 2.58791132503355 0.00198396641352357 0.0401753198738523 GO:0003712 transcription coregulator activity 51/1271 495/18639 0.103030303030303 1.51092196552464 0.00210991428111409 0.0404955253287693 GO:0004712 protein serine/threonine/tyrosine kinase activity 9/1271 43/18639 0.209302325581395 3.0693831994584 0.00211438341832354 0.0404955253287693 GO:0048156 tau protein binding 9/1271 43/18639 0.209302325581395 3.0693831994584 0.00211438341832354 0.0404955253287693 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 50/1271 484/18639 0.103305785123967 1.51496186382818 0.00219565641286585 0.0404955253287693 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 11/1271 60/18639 0.183333333333333 2.68855232100708 0.00220058099811045 0.0404955253287693 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 6/1271 21/18639 0.285714285714286 4.18995166910194 0.00221404106735776 0.0404955253287693 GO:0019207 kinase regulator activity 33/1271 287/18639 0.114982578397213 1.68620006195566 0.00226734446790437 0.0408122004222787 GO:0005041 low-density lipoprotein particle receptor activity 5/1271 15/18639 0.333333333333333 4.8882769472856 0.00246539028973141 0.0432593892601171 GO:0003954 NADH dehydrogenase activity 9/1271 44/18639 0.204545454545455 2.9996244903798 0.00250003461083997 0.0432593892601171 GO:0008186 ATP-dependent activity, acting on RNA 13/1271 79/18639 0.164556962025316 2.41320001195112 0.00251774223207031 0.0432593892601171 GO:0033192 calmodulin-dependent protein phosphatase activity 13/1271 81/18639 0.160493827160494 2.35361482647085 0.00315725638853642 0.0476961525991703 GO:0140791 histone H2AXS140 phosphatase activity 13/1271 81/18639 0.160493827160494 2.35361482647085 0.00315725638853642 0.0476961525991703 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 13/1271 81/18639 0.160493827160494 2.35361482647085 0.00315725638853642 0.0476961525991703 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 13/1271 81/18639 0.160493827160494 2.35361482647085 0.00315725638853642 0.0476961525991703 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 13/1271 81/18639 0.160493827160494 2.35361482647085 0.00315725638853642 0.0476961525991703 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 13/1271 81/18639 0.160493827160494 2.35361482647085 0.00315725638853642 0.0476961525991703 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 13/1271 81/18639 0.160493827160494 2.35361482647085 0.00315725638853642 0.0476961525991703 GO:1990439 MAP kinase serine/threonine phosphatase activity 13/1271 81/18639 0.160493827160494 2.35361482647085 0.00315725638853642 0.0476961525991703 GO:0030957 Tat protein binding 4/1271 10/18639 0.4 5.86593233674272 0.00323862764562267 0.0476961525991703 GO:0031720 haptoglobin binding 4/1271 10/18639 0.4 5.86593233674272 0.00323862764562267 0.0476961525991703 GO:0032395 MHC class II receptor activity 4/1271 10/18639 0.4 5.86593233674272 0.00323862764562267 0.0476961525991703 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 13/1271 82/18639 0.158536585365854 2.32491220663583 0.00352332060419702 0.0505752603184737 GO:0033549 MAP kinase phosphatase activity 13/1271 82/18639 0.158536585365854 2.32491220663583 0.00352332060419702 0.0505752603184737 GO:0042171 lysophosphatidic acid acyltransferase activity 6/1271 23/18639 0.260869565217391 3.82560804570178 0.0036628388424965 0.051279743794951 GO:0071617 lysophospholipid acyltransferase activity 6/1271 23/18639 0.260869565217391 3.82560804570178 0.0036628388424965 0.051279743794951 GO:0140713 histone chaperone activity 21/1271 164/18639 0.128048780487805 1.87781370535971 0.00391597721867969 0.0541550995851557 GO:0017018 myosin phosphatase activity 13/1271 84/18639 0.154761904761905 2.26955715409689 0.00435869843507567 0.0595513737997086 GO:0016887 ATP hydrolysis activity 43/1271 417/18639 0.103117505995204 1.51220078225382 0.00444235541840101 0.0599717981484136 GO:0048027 mRNA 5'-UTR binding 6/1271 24/18639 0.25 3.6662077104642 0.00460618935552781 0.0614519850490416 GO:0019887 protein kinase regulator activity 29/1271 255/18639 0.113725490196078 1.66776507613273 0.00472087983191226 0.0622497410394012 GO:0042608 T cell receptor binding 4/1271 11/18639 0.363636363636364 5.3326657606752 0.00481648577843508 0.0627804008361539 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 10/1271 58/18639 0.172413793103448 2.52841911066497 0.00543500948121717 0.0692505702438233 GO:0061980 regulatory RNA binding 10/1271 58/18639 0.172413793103448 2.52841911066497 0.00543500948121717 0.0692505702438233 GO:0003724 RNA helicase activity 12/1271 77/18639 0.155844155844156 2.28542818314652 0.00570174794615406 0.0718420241215411 GO:1990841 promoter-specific chromatin binding 11/1271 68/18639 0.161764705882353 2.37225204794742 0.0059880814726969 0.0746207075828383 GO:0003714 transcription corepressor activity 24/1271 204/18639 0.117647058823529 1.72527421668904 0.006349250834484 0.0782614178946179 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 4/1271 12/18639 0.333333333333333 4.8882769472856 0.00683847650128049 0.0819606921924414 GO:0016830 carbon-carbon lyase activity 9/1271 51/18639 0.176470588235294 2.58791132503355 0.00699665168044801 0.0819606921924414 GO:0030544 Hsp70 protein binding 9/1271 51/18639 0.176470588235294 2.58791132503355 0.00699665168044801 0.0819606921924414 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 6/1271 26/18639 0.230769230769231 3.38419173273619 0.00701074703938872 0.0819606921924414 GO:0008143 poly(A) binding 6/1271 26/18639 0.230769230769231 3.38419173273619 0.00701074703938872 0.0819606921924414 GO:0003727 single-stranded RNA binding 13/1271 89/18639 0.146067415730337 2.14205394319257 0.00715655375672326 0.082811550613512 GO:0045296 cadherin binding 35/1271 334/18639 0.104790419161677 1.53673377085326 0.00754683149105516 0.0864455243520864 GO:0035255 ionotropic glutamate receptor binding 6/1271 27/18639 0.222222222222222 3.2588512981904 0.0085038818104558 0.0964340197305687 GO:0001046 core promoter sequence-specific DNA binding 8/1271 44/18639 0.181818181818182 2.6663328803376 0.00896870825549197 0.100334401317465 GO:0140296 general transcription initiation factor binding 9/1271 53/18639 0.169811320754717 2.49025429390021 0.00902478742008944 0.100334401317465 GO:0008035 high-density lipoprotein particle binding 4/1271 13/18639 0.307692307692308 4.51225564364825 0.00935108428915807 0.102952714406847 GO:0031418 L-ascorbic acid binding 5/1271 20/18639 0.25 3.6662077104642 0.00957214686609136 0.104373216789881 GO:0004722 protein serine/threonine phosphatase activity 14/1271 103/18639 0.135922330097087 1.99327797850481 0.0100895250740598 0.10801764899616 GO:0017069 snRNA binding 9/1271 54/18639 0.166666666666667 2.4441384736428 0.0101918443748954 0.10801764899616 GO:0097718 disordered domain specific binding 6/1271 28/18639 0.214285714285714 3.14246375182646 0.0102118171590821 0.10801764899616 GO:0051213 dioxygenase activity 13/1271 93/18639 0.139784946236559 2.04992259079719 0.0102873951424915 0.10801764899616 GO:0140789 histone phosphatase activity 17/1271 136/18639 0.125 1.8331038552321 0.0111619390900925 0.116125127781329 GO:0043394 proteoglycan binding 7/1271 37/18639 0.189189189189189 2.7744274565675 0.0114128655074675 0.11765626804971 GO:0016922 nuclear receptor binding 17/1271 137/18639 0.124087591240876 1.81972353512092 0.0119597191499731 0.122183076721347 GO:0005344 oxygen carrier activity 4/1271 14/18639 0.285714285714286 4.18995166910194 0.0123952841263049 0.125502251778837 GO:0005126 cytokine receptor binding 29/1271 275/18639 0.105454545454545 1.54647307059581 0.0129853006175005 0.130312662834032 GO:0001968 fibronectin binding 6/1271 30/18639 0.2 2.93296616837136 0.0143321749203419 0.142567424207612 GO:0061133 endopeptidase activator activity 5/1271 22/18639 0.227272727272727 3.332916100422 0.0145188535657137 0.143168521247994 GO:0140693 molecular condensate scaffold activity 8/1271 48/18639 0.166666666666667 2.4441384736428 0.015025616801067 0.146888357348362 GO:0003823 antigen binding 20/1271 174/18639 0.114942528735632 1.68561274044331 0.0151997382080462 0.147320539554909 GO:0004725 protein tyrosine phosphatase activity 13/1271 98/18639 0.13265306122449 1.94533470351162 0.0155934226505198 0.149855434624487 GO:0000774 adenyl-nucleotide exchange factor activity 4/1271 15/18639 0.266666666666667 3.91062155782848 0.0160061546123316 0.150634586844675 GO:0140776 protein-containing complex destabilizing activity 4/1271 15/18639 0.266666666666667 3.91062155782848 0.0160061546123316 0.150634586844675 GO:0003713 transcription coactivator activity 27/1271 256/18639 0.10546875 1.54668137785208 0.0160730026527387 0.150634586844675 GO:0008094 ATP-dependent activity, acting on DNA 23/1271 210/18639 0.10952380952381 1.60614813982241 0.0166829632691057 0.155069511042343 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 12/1271 89/18639 0.134831460674157 1.97728056294698 0.0174795349154098 0.159072196650662 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 12/1271 89/18639 0.134831460674157 1.97728056294698 0.0174795349154098 0.159072196650662 GO:0008171 O-methyltransferase activity 5/1271 23/18639 0.217391304347826 3.18800670475148 0.0175344132110518 0.159072196650662 GO:0036002 pre-mRNA binding 9/1271 59/18639 0.152542372881356 2.23700809452053 0.0177943367482994 0.160149030734694 GO:0140793 histone H2AXY142 phosphatase activity 12/1271 90/18639 0.133333333333333 1.95531077891424 0.0189598970735259 0.169295458908491 GO:0043425 bHLH transcription factor binding 6/1271 32/18639 0.1875 2.74965578284815 0.0194855726099562 0.171291777827057 GO:0070717 poly-purine tract binding 6/1271 32/18639 0.1875 2.74965578284815 0.0194855726099562 0.171291777827057 GO:0042287 MHC protein binding 7/1271 41/18639 0.170731707317073 2.50375160714628 0.019688478214846 0.171619439753253 GO:0097110 scaffold protein binding 10/1271 70/18639 0.142857142857143 2.09497583455097 0.0198255261090618 0.171619439753253 GO:0005200 structural constituent of cytoskeleton 14/1271 112/18639 0.125 1.8331038552321 0.0200534746204163 0.172277577420849 GO:0017070 U6 snRNA binding 4/1271 16/18639 0.25 3.6662077104642 0.0202126810718708 0.172339701770688 GO:0001091 RNA polymerase II general transcription initiation factor binding 5/1271 24/18639 0.208333333333333 3.0551730920535 0.0209365773835581 0.173299844912079 GO:0015149 hexose transmembrane transporter activity 5/1271 24/18639 0.208333333333333 3.0551730920535 0.0209365773835581 0.173299844912079 GO:0035035 histone acetyltransferase binding 5/1271 24/18639 0.208333333333333 3.0551730920535 0.0209365773835581 0.173299844912079 GO:0055056 D-glucose transmembrane transporter activity 5/1271 24/18639 0.208333333333333 3.0551730920535 0.0209365773835581 0.173299844912079 GO:0042056 chemoattractant activity 7/1271 42/18639 0.166666666666667 2.4441384736428 0.0222789386510282 0.183074756741058 GO:0030296 protein tyrosine kinase activator activity 6/1271 33/18639 0.181818181818182 2.6663328803376 0.0224818038550974 0.183412701954536 GO:0019001 guanyl nucleotide binding 38/1271 400/18639 0.095 1.3931589299764 0.0241137581474725 0.193936182547757 GO:0032561 guanyl ribonucleotide binding 38/1271 400/18639 0.095 1.3931589299764 0.0241137581474725 0.193936182547757 GO:0030695 GTPase regulator activity 45/1271 489/18639 0.0920245398773006 1.34952431060032 0.0248967122540463 0.195812188441054 GO:0001540 amyloid-beta binding 11/1271 83/18639 0.132530120481928 1.94353179831837 0.0250337933716726 0.195812188441054 GO:0004549 tRNA-specific ribonuclease activity 4/1271 17/18639 0.235294117647059 3.45054843337807 0.0250377136895528 0.195812188441054 GO:1990226 histone methyltransferase binding 4/1271 17/18639 0.235294117647059 3.45054843337807 0.0250377136895528 0.195812188441054 GO:0060589 nucleoside-triphosphatase regulator activity 45/1271 490/18639 0.0918367346938776 1.3467701793542 0.0256715301778226 0.197476823712447 GO:0016831 carboxy-lyase activity 6/1271 34/18639 0.176470588235294 2.58791132503355 0.0257729893381324 0.197476823712447 GO:0090482 vitamin transmembrane transporter activity 6/1271 34/18639 0.176470588235294 2.58791132503355 0.0257729893381324 0.197476823712447 GO:0009055 electron transfer activity 14/1271 116/18639 0.120689655172414 1.76989337746548 0.0263312609822108 0.198412089112857 GO:0051880 G-quadruplex DNA binding 3/1271 10/18639 0.3 4.39944925255704 0.0264199519012711 0.198412089112857 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 3/1271 10/18639 0.3 4.39944925255704 0.0264199519012711 0.198412089112857 GO:0005525 GTP binding 36/1271 378/18639 0.0952380952380952 1.39665055636731 0.0266669502968787 0.198949484451714 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 15/1271 128/18639 0.1171875 1.71853486428009 0.0278787766028048 0.206630932467847 GO:0008198 ferrous iron binding 5/1271 26/18639 0.192307692307692 2.82015977728016 0.0289631305258588 0.210682305197551 GO:0015145 monosaccharide transmembrane transporter activity 5/1271 26/18639 0.192307692307692 2.82015977728016 0.0289631305258588 0.210682305197551 GO:0140463 chromatin-protein adaptor activity 8/1271 54/18639 0.148148148148148 2.17256753212693 0.0289827509795573 0.210682305197551 GO:0016229 steroid dehydrogenase activity 6/1271 35/18639 0.171428571428571 2.51397100146117 0.0293692627043541 0.212132126794507 GO:0022853 active monoatomic ion transmembrane transporter activity 14/1271 118/18639 0.11864406779661 1.73989518462708 0.029966013410294 0.212426837407881 GO:0003735 structural constituent of ribosome 19/1271 175/18639 0.108571428571429 1.59218163425874 0.0299720405513765 0.212426837407881 GO:0004721 phosphoprotein phosphatase activity 19/1271 175/18639 0.108571428571429 1.59218163425874 0.0299720405513765 0.212426837407881 GO:0034185 apolipoprotein binding 4/1271 18/18639 0.222222222222222 3.2588512981904 0.0304980505352108 0.214812355943658 GO:0008009 chemokine activity 7/1271 45/18639 0.155555555555556 2.28119590873328 0.0314394483577108 0.220076138503976 GO:0008374 O-acyltransferase activity 8/1271 55/18639 0.145454545454545 2.13306630427008 0.0319638426556947 0.222374218230416 GO:0016791 phosphatase activity 27/1271 273/18639 0.0989010989010989 1.45036788545837 0.0333504392889444 0.230606086302823 GO:0015399 primary active transmembrane transporter activity 18/1271 166/18639 0.108433734939759 1.5901623804423 0.0343274492935897 0.233018448957009 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 3/1271 11/18639 0.272727272727273 3.9994993205064 0.0345212516973347 0.233018448957009 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 3/1271 11/18639 0.272727272727273 3.9994993205064 0.0345212516973347 0.233018448957009 GO:0048185 activin binding 3/1271 11/18639 0.272727272727273 3.9994993205064 0.0345212516973347 0.233018448957009 GO:0042578 phosphoric ester hydrolase activity 34/1271 363/18639 0.09366391184573 1.37356542320422 0.0374777692240136 0.251478049112612 GO:0016504 peptidase activator activity 8/1271 57/18639 0.140350877192982 2.05822187254131 0.0385387400149446 0.252218314748183 GO:0051019 mitogen-activated protein kinase binding 5/1271 28/18639 0.178571428571429 2.61871979318872 0.0387001646968112 0.252218314748183 GO:0051119 sugar transmembrane transporter activity 5/1271 28/18639 0.178571428571429 2.61871979318872 0.0387001646968112 0.252218314748183 GO:0051537 2 iron, 2 sulfur cluster binding 5/1271 28/18639 0.178571428571429 2.61871979318872 0.0387001646968112 0.252218314748183 GO:0141052 histone H3 demethylase activity 5/1271 28/18639 0.178571428571429 2.61871979318872 0.0387001646968112 0.252218314748183 GO:0042162 telomeric DNA binding 6/1271 38/18639 0.157894736842105 2.31549960660897 0.0420726932447164 0.272631052225762 GO:0000339 RNA cap binding 4/1271 20/18639 0.2 2.93296616837136 0.0433627377960985 0.275617713604922 GO:0004526 ribonuclease P activity 3/1271 12/18639 0.25 3.6662077104642 0.0437488434293527 0.275617713604922 GO:0016840 carbon-nitrogen lyase activity 3/1271 12/18639 0.25 3.6662077104642 0.0437488434293527 0.275617713604922 GO:0031543 peptidyl-proline dioxygenase activity 3/1271 12/18639 0.25 3.6662077104642 0.0437488434293527 0.275617713604922 GO:0097677 STAT family protein binding 3/1271 12/18639 0.25 3.6662077104642 0.0437488434293527 0.275617713604922 GO:0002039 p53 binding 9/1271 69/18639 0.130434782608696 1.91280402285089 0.0440376853929648 0.275904614561448 GO:0019209 kinase activator activity 16/1271 148/18639 0.108108108108108 1.58538711803857 0.0451688723014476 0.281436819724404 GO:0070063 RNA polymerase binding 8/1271 59/18639 0.135593220338983 1.9884516395738 0.0459611852956527 0.284391337036488 GO:0008201 heparin binding 18/1271 172/18639 0.104651162790698 1.5346915997292 0.0461446261152678 0.284391337036488 GO:0035254 glutamate receptor binding 7/1271 49/18639 0.142857142857143 2.09497583455097 0.0471496431233686 0.289014569199459 GO:0001098 basal transcription machinery binding 8/1271 60/18639 0.133333333333333 1.95531077891424 0.0499999806611782 0.302870738618451 GO:0001099 basal RNA polymerase II transcription machinery binding 8/1271 60/18639 0.133333333333333 1.95531077891424 0.0499999806611782 0.302870738618451 GO:0032452 histone demethylase activity 5/1271 30/18639 0.166666666666667 2.4441384736428 0.0502113746563217 0.302870738618451 GO:0035613 RNA stem-loop binding 4/1271 21/18639 0.19047619047619 2.79330111273463 0.0507724278826639 0.30303122746811 GO:0070182 DNA polymerase binding 4/1271 21/18639 0.19047619047619 2.79330111273463 0.0507724278826639 0.30303122746811 GO:0048020 CCR chemokine receptor binding 7/1271 50/18639 0.14 2.05307631785995 0.0517367404490046 0.306131380951827 GO:0030295 protein kinase activator activity 15/1271 139/18639 0.107913669064748 1.58253570235865 0.0519074265227279 0.306131380951827 GO:0032451 demethylase activity 6/1271 40/18639 0.15 2.19972462627852 0.0521999678846442 0.306131380951827 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 3/1271 13/18639 0.230769230769231 3.38419173273619 0.0540681711714111 0.306131380951827 GO:0005172 vascular endothelial growth factor receptor binding 3/1271 13/18639 0.230769230769231 3.38419173273619 0.0540681711714111 0.306131380951827 GO:0005542 folic acid binding 3/1271 13/18639 0.230769230769231 3.38419173273619 0.0540681711714111 0.306131380951827 GO:0017154 semaphorin receptor activity 3/1271 13/18639 0.230769230769231 3.38419173273619 0.0540681711714111 0.306131380951827 GO:0051011 microtubule minus-end binding 3/1271 13/18639 0.230769230769231 3.38419173273619 0.0540681711714111 0.306131380951827 GO:0097157 pre-mRNA intronic binding 3/1271 13/18639 0.230769230769231 3.38419173273619 0.0540681711714111 0.306131380951827 GO:0015026 coreceptor activity 8/1271 61/18639 0.131147540983607 1.92325650385007 0.0542613823380222 0.306131380951827 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 8/1271 61/18639 0.131147540983607 1.92325650385007 0.0542613823380222 0.306131380951827 GO:0003743 translation initiation factor activity 7/1271 51/18639 0.137254901960784 2.01281991947054 0.0565949081072141 0.313325932562326 GO:0005164 tumor necrosis factor receptor binding 5/1271 31/18639 0.161290322580645 2.36529529707368 0.0566418132057116 0.313325932562326 GO:0070325 lipoprotein particle receptor binding 5/1271 31/18639 0.161290322580645 2.36529529707368 0.0566418132057116 0.313325932562326 GO:0140457 protein demethylase activity 5/1271 31/18639 0.161290322580645 2.36529529707368 0.0566418132057116 0.313325932562326 GO:0001530 lipopolysaccharide binding 6/1271 41/18639 0.146341463414634 2.14607280612539 0.0577733661137525 0.3180339668592 GO:0140517 protein-RNA adaptor activity 4/1271 22/18639 0.181818181818182 2.6663328803376 0.0588287777308751 0.322279391047403 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 5/1271 32/18639 0.15625 2.29137981904013 0.0635225985012218 0.343525896009947 GO:0008307 structural constituent of muscle 6/1271 42/18639 0.142857142857143 2.09497583455097 0.0636891040242065 0.343525896009947 GO:0048029 monosaccharide binding 9/1271 74/18639 0.121621621621622 1.7835605077934 0.0637914442932724 0.343525896009947 GO:0005161 platelet-derived growth factor receptor binding 3/1271 14/18639 0.214285714285714 3.14246375182646 0.0654335040018947 0.343525896009947 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 3/1271 14/18639 0.214285714285714 3.14246375182646 0.0654335040018947 0.343525896009947 GO:0043176 amine binding 3/1271 14/18639 0.214285714285714 3.14246375182646 0.0654335040018947 0.343525896009947 GO:0044548 S100 protein binding 3/1271 14/18639 0.214285714285714 3.14246375182646 0.0654335040018947 0.343525896009947 GO:0070742 C2H2 zinc finger domain binding 3/1271 14/18639 0.214285714285714 3.14246375182646 0.0654335040018947 0.343525896009947 GO:0098847 sequence-specific single stranded DNA binding 3/1271 14/18639 0.214285714285714 3.14246375182646 0.0654335040018947 0.343525896009947 GO:0005246 calcium channel regulator activity 7/1271 53/18639 0.132075471698113 1.93686445081128 0.0671327842901471 0.349213657729481 GO:0016860 intramolecular oxidoreductase activity 7/1271 53/18639 0.132075471698113 1.93686445081128 0.0671327842901471 0.349213657729481 GO:0005085 guanyl-nucleotide exchange factor activity 22/1271 230/18639 0.0956521739130435 1.40272295009065 0.0680454365436513 0.352344863198633 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 18/1271 181/18639 0.0994475138121547 1.45838096769847 0.0689134523707599 0.355217522674735 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 13/1271 122/18639 0.10655737704918 1.56264590937818 0.0725048726086221 0.371945380632138 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 7/1271 54/18639 0.12962962962963 1.90099659061107 0.0728147041449158 0.371945380632138 GO:0019843 rRNA binding 8/1271 65/18639 0.123076923076923 1.8049022574593 0.0735760191043449 0.374148904324337 GO:0016651 oxidoreductase activity, acting on NAD(P)H 10/1271 88/18639 0.113636363636364 1.666458050211 0.0762075501175896 0.385215052795151 GO:0004129 cytochrome-c oxidase activity 3/1271 15/18639 0.2 2.93296616837136 0.0777903413492854 0.385215052795151 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 3/1271 15/18639 0.2 2.93296616837136 0.0777903413492854 0.385215052795151 GO:0031386 protein tag activity 3/1271 15/18639 0.2 2.93296616837136 0.0777903413492854 0.385215052795151 GO:0050780 dopamine receptor binding 3/1271 15/18639 0.2 2.93296616837136 0.0777903413492854 0.385215052795151 GO:0141047 molecular tag activity 3/1271 15/18639 0.2 2.93296616837136 0.0777903413492854 0.385215052795151 GO:0019825 oxygen binding 5/1271 34/18639 0.147058823529412 2.1565927708613 0.0786234363986032 0.387647725547896 GO:0033218 amide binding 23/1271 247/18639 0.0931174089068826 1.36555105005144 0.0797805604856151 0.39165002420211 GO:0140030 modification-dependent protein binding 17/1271 173/18639 0.0982658959537572 1.44105274168535 0.0821783246739898 0.401681983535795 GO:0005178 integrin binding 16/1271 161/18639 0.0993788819875776 1.45737449360068 0.0830657161630231 0.404276919008018 GO:0019210 kinase inhibitor activity 10/1271 90/18639 0.111111111111111 1.6294256490952 0.0857302697914818 0.415462076681796 GO:0042974 nuclear retinoic acid receptor binding 4/1271 25/18639 0.16 2.34637293469709 0.0867628992617882 0.418677139416459 GO:0019842 vitamin binding 15/1271 150/18639 0.1 1.46648308418568 0.0874875204878666 0.420384950140851 GO:0016829 lyase activity 19/1271 200/18639 0.095 1.3931589299764 0.0895407833238308 0.428435646789975 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/1271 16/18639 0.1875 2.74965578284815 0.0910774937209964 0.432141748450251 GO:0097027 ubiquitin-protein transferase activator activity 3/1271 16/18639 0.1875 2.74965578284815 0.0910774937209964 0.432141748450251 GO:0004601 peroxidase activity 7/1271 57/18639 0.12280701754386 1.80094413847364 0.0915093710022004 0.432381777985397 GO:0001217 DNA-binding transcription repressor activity 25/1271 278/18639 0.0899280575539568 1.31877975196554 0.0954407139176078 0.449086180840528 GO:0043021 ribonucleoprotein complex binding 17/1271 177/18639 0.096045197740113 1.40848657803144 0.0963719349609845 0.45023015988298 GO:0031490 chromatin DNA binding 13/1271 128/18639 0.1015625 1.48939688237608 0.0969657751808046 0.45023015988298 GO:0050681 nuclear androgen receptor binding 4/1271 26/18639 0.153846153846154 2.25612782182412 0.097271948122866 0.45023015988298 GO:0050750 low-density lipoprotein particle receptor binding 4/1271 26/18639 0.153846153846154 2.25612782182412 0.097271948122866 0.45023015988298 GO:0005539 glycosaminoglycan binding 22/1271 242/18639 0.0909090909090909 1.3331664401688 0.103023208639043 0.47210670505598 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 24/1271 268/18639 0.0895522388059701 1.31326843359912 0.104143393724916 0.47210670505598 GO:0004550 nucleoside diphosphate kinase activity 3/1271 17/18639 0.176470588235294 2.58791132503355 0.105228875156306 0.47210670505598 GO:0004659 prenyltransferase activity 3/1271 17/18639 0.176470588235294 2.58791132503355 0.105228875156306 0.47210670505598 GO:0005092 GDP-dissociation inhibitor activity 3/1271 17/18639 0.176470588235294 2.58791132503355 0.105228875156306 0.47210670505598 GO:0048038 quinone binding 3/1271 17/18639 0.176470588235294 2.58791132503355 0.105228875156306 0.47210670505598 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 7/1271 59/18639 0.11864406779661 1.73989518462708 0.10532892096928 0.47210670505598 GO:0070888 E-box binding 7/1271 59/18639 0.11864406779661 1.73989518462708 0.10532892096928 0.47210670505598 GO:0005385 zinc ion transmembrane transporter activity 4/1271 27/18639 0.148148148148148 2.17256753212693 0.108343076530432 0.483704916478388 GO:0004714 transmembrane receptor protein tyrosine kinase activity 7/1271 60/18639 0.116666666666667 1.71089693154996 0.112636516859029 0.500901216149563 GO:0140097 catalytic activity, acting on DNA 29/1271 336/18639 0.0863095238095238 1.26571456670788 0.113420094508324 0.502415574892343 GO:0001664 G protein-coupled receptor binding 26/1271 297/18639 0.0875420875420875 1.28378990534773 0.114031705908248 0.503159356030945 GO:0001222 transcription corepressor binding 6/1271 49/18639 0.122448979591837 1.79569357247226 0.114560029908801 0.503531294250313 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 13/1271 132/18639 0.0984848484848485 1.4442636435162 0.115765665339796 0.504786337397396 GO:0005518 collagen binding 8/1271 72/18639 0.111111111111111 1.6294256490952 0.116180982416861 0.504786337397396 GO:0042379 chemokine receptor binding 8/1271 72/18639 0.111111111111111 1.6294256490952 0.116180982416861 0.504786337397396 GO:0004860 protein kinase inhibitor activity 9/1271 84/18639 0.107142857142857 1.57123187591323 0.117912289384563 0.50661150725396 GO:0051117 ATPase binding 9/1271 84/18639 0.107142857142857 1.57123187591323 0.117912289384563 0.50661150725396 GO:0046875 ephrin receptor binding 4/1271 28/18639 0.142857142857143 2.09497583455097 0.119950228502703 0.50661150725396 GO:0046966 nuclear thyroid hormone receptor binding 4/1271 28/18639 0.142857142857143 2.09497583455097 0.119950228502703 0.50661150725396 GO:0000900 mRNA regulatory element binding translation repressor activity 3/1271 18/18639 0.166666666666667 2.4441384736428 0.120175040080525 0.50661150725396 GO:0031690 adrenergic receptor binding 3/1271 18/18639 0.166666666666667 2.4441384736428 0.120175040080525 0.50661150725396 GO:0050811 GABA receptor binding 3/1271 18/18639 0.166666666666667 2.4441384736428 0.120175040080525 0.50661150725396 GO:1901611 phosphatidylglycerol binding 3/1271 18/18639 0.166666666666667 2.4441384736428 0.120175040080525 0.50661150725396 GO:0032813 tumor necrosis factor receptor superfamily binding 6/1271 50/18639 0.12 1.75977970102282 0.123126842107865 0.517132736853032 GO:1901681 sulfur compound binding 24/1271 275/18639 0.0872727272727273 1.27983978256205 0.127843727659878 0.534962314266796 GO:0016209 antioxidant activity 9/1271 86/18639 0.104651162790698 1.5346915997292 0.13105437425374 0.538763631380526 GO:0005021 vascular endothelial growth factor receptor activity 6/1271 51/18639 0.117647058823529 1.72527421668904 0.131997766641285 0.538763631380526 GO:0005048 signal sequence binding 6/1271 51/18639 0.117647058823529 1.72527421668904 0.131997766641285 0.538763631380526 GO:0004629 phospholipase C activity 4/1271 29/18639 0.137931034482759 2.02273528853197 0.13206522377775 0.538763631380526 GO:0051861 glycolipid binding 4/1271 29/18639 0.137931034482759 2.02273528853197 0.13206522377775 0.538763631380526 GO:0015144 carbohydrate transmembrane transporter activity 5/1271 40/18639 0.125 1.8331038552321 0.134079615327918 0.538763631380526 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 3/1271 19/18639 0.157894736842105 2.31549960660897 0.13584449391873 0.538763631380526 GO:0015245 fatty acid transmembrane transporter activity 3/1271 19/18639 0.157894736842105 2.31549960660897 0.13584449391873 0.538763631380526 GO:0046624 sphingolipid transporter activity 3/1271 19/18639 0.157894736842105 2.31549960660897 0.13584449391873 0.538763631380526 GO:0097001 ceramide binding 3/1271 19/18639 0.157894736842105 2.31549960660897 0.13584449391873 0.538763631380526 GO:0140036 ubiquitin-modified protein reader activity 3/1271 19/18639 0.157894736842105 2.31549960660897 0.13584449391873 0.538763631380526 GO:0002020 protease binding 13/1271 136/18639 0.0955882352941176 1.40178530105984 0.136534999764314 0.538763631380526 GO:0019838 growth factor binding 13/1271 136/18639 0.0955882352941176 1.40178530105984 0.136534999764314 0.538763631380526 GO:0003725 double-stranded RNA binding 8/1271 75/18639 0.106666666666667 1.56424862313139 0.137766368722224 0.538763631380526 GO:0031406 carboxylic acid binding 17/1271 187/18639 0.0909090909090909 1.3331664401688 0.138210268863931 0.538763631380526 GO:0043022 ribosome binding 11/1271 112/18639 0.0982142857142857 1.44029588625379 0.141580146975052 0.538763631380526 GO:0008187 poly-pyrimidine tract binding 4/1271 30/18639 0.133333333333333 1.95531077891424 0.144658123642585 0.538763631380526 GO:0048019 receptor antagonist activity 4/1271 30/18639 0.133333333333333 1.95531077891424 0.144658123642585 0.538763631380526 GO:0140318 protein transporter activity 5/1271 41/18639 0.121951219512195 1.78839400510449 0.144677705496552 0.538763631380526 GO:0001094 TFIID-class transcription factor complex binding 2/1271 10/18639 0.2 2.93296616837136 0.145347543627723 0.538763631380526 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 2/1271 10/18639 0.2 2.93296616837136 0.145347543627723 0.538763631380526 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/1271 10/18639 0.2 2.93296616837136 0.145347543627723 0.538763631380526 GO:0004090 carbonyl reductase (NADPH) activity 2/1271 10/18639 0.2 2.93296616837136 0.145347543627723 0.538763631380526 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 2/1271 10/18639 0.2 2.93296616837136 0.145347543627723 0.538763631380526 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/1271 10/18639 0.2 2.93296616837136 0.145347543627723 0.538763631380526 GO:0005031 tumor necrosis factor receptor activity 2/1271 10/18639 0.2 2.93296616837136 0.145347543627723 0.538763631380526 GO:0008140 cAMP response element binding protein binding 2/1271 10/18639 0.2 2.93296616837136 0.145347543627723 0.538763631380526 GO:0008190 eukaryotic initiation factor 4E binding 2/1271 10/18639 0.2 2.93296616837136 0.145347543627723 0.538763631380526 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/1271 10/18639 0.2 2.93296616837136 0.145347543627723 0.538763631380526 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 2/1271 10/18639 0.2 2.93296616837136 0.145347543627723 0.538763631380526 GO:0031996 thioesterase binding 2/1271 10/18639 0.2 2.93296616837136 0.145347543627723 0.538763631380526 GO:0032052 bile acid binding 2/1271 10/18639 0.2 2.93296616837136 0.145347543627723 0.538763631380526 GO:0033204 ribonuclease P RNA binding 2/1271 10/18639 0.2 2.93296616837136 0.145347543627723 0.538763631380526 GO:0141109 transporter activator activity 2/1271 10/18639 0.2 2.93296616837136 0.145347543627723 0.538763631380526 GO:0051536 iron-sulfur cluster binding 8/1271 76/18639 0.105263157894737 1.54366640440598 0.145380662436015 0.538763631380526 GO:0043177 organic acid binding 17/1271 189/18639 0.0899470899470899 1.31905885879135 0.147652425840551 0.54540016580842 GO:0140098 catalytic activity, acting on RNA 32/1271 387/18639 0.082687338501292 1.2125958318848 0.149072951190885 0.548859502111895 GO:0043024 ribosomal small subunit binding 3/1271 20/18639 0.15 2.19972462627852 0.152164803822724 0.556628669467641 GO:0052745 inositol phosphate phosphatase activity 3/1271 20/18639 0.15 2.19972462627852 0.152164803822724 0.556628669467641 GO:0051540 metal cluster binding 8/1271 77/18639 0.103896103896104 1.52361878876434 0.153196797676908 0.558601828185252 GO:0004402 histone acetyltransferase activity 5/1271 42/18639 0.119047619047619 1.74581319545914 0.155622111100923 0.562023802510977 GO:0043175 RNA polymerase core enzyme binding 5/1271 42/18639 0.119047619047619 1.74581319545914 0.155622111100923 0.562023802510977 GO:0051879 Hsp90 protein binding 5/1271 42/18639 0.119047619047619 1.74581319545914 0.155622111100923 0.562023802510977 GO:0003925 G protein activity 6/1271 54/18639 0.111111111111111 1.6294256490952 0.160339289544129 0.571965400713044 GO:0019199 transmembrane receptor protein kinase activity 8/1271 78/18639 0.102564102564103 1.50408521454942 0.161209536384236 0.571965400713044 GO:0005096 GTPase activator activity 23/1271 271/18639 0.0848708487084871 1.24461663971478 0.163763629313341 0.571965400713044 GO:0005506 iron ion binding 14/1271 154/18639 0.0909090909090909 1.3331664401688 0.166402997482904 0.571965400713044 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/1271 21/18639 0.142857142857143 2.09497583455097 0.169063533146067 0.571965400713044 GO:0046332 SMAD binding 8/1271 79/18639 0.10126582278481 1.48504616120069 0.169413273907811 0.571965400713044 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0005114 type II transforming growth factor beta receptor binding 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0008432 JUN kinase binding 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0010854 adenylate cyclase regulator activity 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0015173 aromatic amino acid transmembrane transporter activity 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0019215 intermediate filament binding 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0032050 clathrin heavy chain binding 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0032404 mismatch repair complex binding 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0034713 type I transforming growth factor beta receptor binding 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0043522 leucine zipper domain binding 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0048407 platelet-derived growth factor binding 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0070697 activin receptor binding 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0070990 snRNP binding 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0097493 structural molecule activity conferring elasticity 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0140031 phosphorylation-dependent protein binding 2/1271 11/18639 0.181818181818182 2.6663328803376 0.169975608501143 0.571965400713044 GO:0030515 snoRNA binding 4/1271 32/18639 0.125 1.8331038552321 0.171151145403414 0.572523300553014 GO:0051059 NF-kappaB binding 4/1271 32/18639 0.125 1.8331038552321 0.171151145403414 0.572523300553014 GO:0042393 histone binding 21/1271 247/18639 0.0850202429149798 1.24680748048175 0.174769732993165 0.582908462394852 GO:0005125 cytokine activity 20/1271 234/18639 0.0854700854700855 1.25340434545785 0.175804377157098 0.584639776235043 GO:0140375 immune receptor activity 14/1271 156/18639 0.0897435897435897 1.31607456273074 0.17813931417244 0.586649751306486 GO:0001223 transcription coactivator binding 5/1271 44/18639 0.113636363636364 1.666458050211 0.178478098942449 0.586649751306486 GO:0019205 nucleobase-containing compound kinase activity 5/1271 44/18639 0.113636363636364 1.666458050211 0.178478098942449 0.586649751306486 GO:0030547 signaling receptor inhibitor activity 5/1271 44/18639 0.113636363636364 1.666458050211 0.178478098942449 0.586649751306486 GO:0030145 manganese ion binding 7/1271 68/18639 0.102941176470588 1.50961493960291 0.179942944559463 0.588395627938429 GO:0030170 pyridoxal phosphate binding 6/1271 56/18639 0.107142857142857 1.57123187591323 0.180565854076343 0.588395627938429 GO:0170055 lipid transmembrane transporter activity 6/1271 56/18639 0.107142857142857 1.57123187591323 0.180565854076343 0.588395627938429 GO:0008013 beta-catenin binding 10/1271 106/18639 0.0943396226415094 1.38347460772234 0.185930643128337 0.599025126448136 GO:0008093 cytoskeletal anchor activity 3/1271 22/18639 0.136363636363636 1.9997496602532 0.186469020843203 0.599025126448136 GO:0008649 rRNA methyltransferase activity 3/1271 22/18639 0.136363636363636 1.9997496602532 0.186469020843203 0.599025126448136 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/1271 22/18639 0.136363636363636 1.9997496602532 0.186469020843203 0.599025126448136 GO:0140035 ubiquitin-like protein reader activity 3/1271 22/18639 0.136363636363636 1.9997496602532 0.186469020843203 0.599025126448136 GO:0070279 vitamin B6 binding 6/1271 57/18639 0.105263157894737 1.54366640440598 0.191043087379184 0.606739311276808 GO:0003995 acyl-CoA dehydrogenase activity 2/1271 12/18639 0.166666666666667 2.4441384736428 0.195220961515501 0.606739311276808 GO:0008603 cAMP-dependent protein kinase regulator activity 2/1271 12/18639 0.166666666666667 2.4441384736428 0.195220961515501 0.606739311276808 GO:0015132 prostaglandin transmembrane transporter activity 2/1271 12/18639 0.166666666666667 2.4441384736428 0.195220961515501 0.606739311276808 GO:0016208 AMP binding 2/1271 12/18639 0.166666666666667 2.4441384736428 0.195220961515501 0.606739311276808 GO:0017166 vinculin binding 2/1271 12/18639 0.166666666666667 2.4441384736428 0.195220961515501 0.606739311276808 GO:0035259 nuclear glucocorticoid receptor binding 2/1271 12/18639 0.166666666666667 2.4441384736428 0.195220961515501 0.606739311276808 GO:0043047 single-stranded telomeric DNA binding 2/1271 12/18639 0.166666666666667 2.4441384736428 0.195220961515501 0.606739311276808 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 2/1271 12/18639 0.166666666666667 2.4441384736428 0.195220961515501 0.606739311276808 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 2/1271 12/18639 0.166666666666667 2.4441384736428 0.195220961515501 0.606739311276808 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/1271 12/18639 0.166666666666667 2.4441384736428 0.195220961515501 0.606739311276808 GO:0015078 proton transmembrane transporter activity 16/1271 185/18639 0.0864864864864865 1.26830969443086 0.195290871795445 0.606739311276808 GO:0015035 protein-disulfide reductase activity 4/1271 34/18639 0.117647058823529 1.72527421668904 0.199167227714244 0.615410452937202 GO:0030332 cyclin binding 4/1271 34/18639 0.117647058823529 1.72527421668904 0.199167227714244 0.615410452937202 GO:0030291 protein serine/threonine kinase inhibitor activity 5/1271 46/18639 0.108695652173913 1.59400335237574 0.202496897471514 0.622819091565236 GO:0031681 G-protein beta-subunit binding 3/1271 23/18639 0.130434782608696 1.91280402285089 0.204311024746268 0.622819091565236 GO:0043274 phospholipase binding 3/1271 23/18639 0.130434782608696 1.91280402285089 0.204311024746268 0.622819091565236 GO:0070577 lysine-acetylated histone binding 3/1271 23/18639 0.130434782608696 1.91280402285089 0.204311024746268 0.622819091565236 GO:0140102 catalytic activity, acting on a rRNA 3/1271 23/18639 0.130434782608696 1.91280402285089 0.204311024746268 0.622819091565236 GO:0045309 protein phosphorylated amino acid binding 6/1271 59/18639 0.101694915254237 1.49133872968035 0.21266104083611 0.646388426332574 GO:0001784 phosphotyrosine residue binding 5/1271 47/18639 0.106382978723404 1.56008838743158 0.214892801346896 0.646388426332574 GO:0061733 protein-lysine-acetyltransferase activity 5/1271 47/18639 0.106382978723404 1.56008838743158 0.214892801346896 0.646388426332574 GO:0061749 forked DNA-dependent helicase activity 5/1271 47/18639 0.106382978723404 1.56008838743158 0.214892801346896 0.646388426332574 GO:1990518 single-stranded 3'-5' DNA helicase activity 5/1271 47/18639 0.106382978723404 1.56008838743158 0.214892801346896 0.646388426332574 GO:0005035 death receptor activity 2/1271 13/18639 0.153846153846154 2.25612782182412 0.220885105214426 0.652038998927247 GO:0019104 DNA N-glycosylase activity 2/1271 13/18639 0.153846153846154 2.25612782182412 0.220885105214426 0.652038998927247 GO:0019855 calcium channel inhibitor activity 2/1271 13/18639 0.153846153846154 2.25612782182412 0.220885105214426 0.652038998927247 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/1271 13/18639 0.153846153846154 2.25612782182412 0.220885105214426 0.652038998927247 GO:0071714 icosanoid transmembrane transporter activity 2/1271 13/18639 0.153846153846154 2.25612782182412 0.220885105214426 0.652038998927247 GO:0089720 caspase binding 2/1271 13/18639 0.153846153846154 2.25612782182412 0.220885105214426 0.652038998927247 GO:0140666 annealing activity 2/1271 13/18639 0.153846153846154 2.25612782182412 0.220885105214426 0.652038998927247 GO:0050699 WW domain binding 3/1271 24/18639 0.125 1.8331038552321 0.222521245665648 0.652038998927247 GO:0070300 phosphatidic acid binding 3/1271 24/18639 0.125 1.8331038552321 0.222521245665648 0.652038998927247 GO:0140033 acetylation-dependent protein binding 3/1271 24/18639 0.125 1.8331038552321 0.222521245665648 0.652038998927247 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 6/1271 60/18639 0.1 1.46648308418568 0.223774876833563 0.654022449302219 GO:0009378 four-way junction helicase activity 5/1271 48/18639 0.104166666666667 1.52758654602675 0.227519208848508 0.657048518886184 GO:0036121 double-stranded DNA helicase activity 5/1271 48/18639 0.104166666666667 1.52758654602675 0.227519208848508 0.657048518886184 GO:0043138 3'-5' DNA helicase activity 5/1271 48/18639 0.104166666666667 1.52758654602675 0.227519208848508 0.657048518886184 GO:0000993 RNA polymerase II complex binding 4/1271 36/18639 0.111111111111111 1.6294256490952 0.228436037738715 0.657048518886184 GO:0055106 ubiquitin-protein transferase regulator activity 4/1271 36/18639 0.111111111111111 1.6294256490952 0.228436037738715 0.657048518886184 GO:0004521 RNA endonuclease activity 7/1271 73/18639 0.0958904109589041 1.40621665606846 0.228866106666704 0.657048518886184 GO:0043539 protein serine/threonine kinase activator activity 7/1271 73/18639 0.0958904109589041 1.40621665606846 0.228866106666704 0.657048518886184 GO:0019905 syntaxin binding 6/1271 61/18639 0.0983606557377049 1.44244237788755 0.235073554605236 0.673165179096811 GO:0003678 DNA helicase activity 7/1271 74/18639 0.0945945945945946 1.38721372828375 0.2391579182812 0.683136219977029 GO:0008139 nuclear localization sequence binding 3/1271 25/18639 0.12 1.75977970102282 0.241033747447992 0.68504328222061 GO:0120020 cholesterol transfer activity 3/1271 25/18639 0.12 1.75977970102282 0.241033747447992 0.68504328222061 GO:0004713 protein tyrosine kinase activity 12/1271 140/18639 0.0857142857142857 1.25698550073058 0.246726698146142 0.691022375166241 GO:0008191 metalloendopeptidase inhibitor activity 2/1271 14/18639 0.142857142857143 2.09497583455097 0.246793705416515 0.691022375166241 GO:0030983 mismatched DNA binding 2/1271 14/18639 0.142857142857143 2.09497583455097 0.246793705416515 0.691022375166241 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 2/1271 14/18639 0.142857142857143 2.09497583455097 0.246793705416515 0.691022375166241 GO:0046030 inositol trisphosphate phosphatase activity 2/1271 14/18639 0.142857142857143 2.09497583455097 0.246793705416515 0.691022375166241 GO:1901612 cardiolipin binding 2/1271 14/18639 0.142857142857143 2.09497583455097 0.246793705416515 0.691022375166241 GO:0003924 GTPase activity 26/1271 331/18639 0.0785498489425982 1.15192024739661 0.253879252177563 0.709111014702847 GO:0043531 ADP binding 4/1271 38/18639 0.105263157894737 1.54366640440598 0.258686832726317 0.710916299284075 GO:0051015 actin filament binding 17/1271 209/18639 0.0813397129186603 1.19283313067735 0.259664943247382 0.710916299284075 GO:0004435 phosphatidylinositol phospholipase C activity 3/1271 26/18639 0.115384615384615 1.69209586636809 0.2597852864904 0.710916299284075 GO:0005160 transforming growth factor beta receptor binding 3/1271 26/18639 0.115384615384615 1.69209586636809 0.2597852864904 0.710916299284075 GO:0008157 protein phosphatase 1 binding 3/1271 26/18639 0.115384615384615 1.69209586636809 0.2597852864904 0.710916299284075 GO:0034237 protein kinase A regulatory subunit binding 3/1271 26/18639 0.115384615384615 1.69209586636809 0.2597852864904 0.710916299284075 GO:0070412 R-SMAD binding 3/1271 26/18639 0.115384615384615 1.69209586636809 0.2597852864904 0.710916299284075 GO:0097602 cullin family protein binding 3/1271 26/18639 0.115384615384615 1.69209586636809 0.2597852864904 0.710916299284075 GO:0098631 cell adhesion mediator activity 7/1271 76/18639 0.0921052631578947 1.35070810385523 0.260167781484031 0.710916299284075 GO:0004857 enzyme inhibitor activity 32/1271 416/18639 0.0769230769230769 1.12806391091206 0.263358552435862 0.717905284765066 GO:0004953 icosanoid receptor activity 2/1271 15/18639 0.133333333333333 1.95531077891424 0.272794222965319 0.726170537189369 GO:0015556 C4-dicarboxylate transmembrane transporter activity 2/1271 15/18639 0.133333333333333 1.95531077891424 0.272794222965319 0.726170537189369 GO:0016846 carbon-sulfur lyase activity 2/1271 15/18639 0.133333333333333 1.95531077891424 0.272794222965319 0.726170537189369 GO:0017081 chloride channel regulator activity 2/1271 15/18639 0.133333333333333 1.95531077891424 0.272794222965319 0.726170537189369 GO:0033130 acetylcholine receptor binding 2/1271 15/18639 0.133333333333333 1.95531077891424 0.272794222965319 0.726170537189369 GO:0042809 nuclear vitamin D receptor binding 2/1271 15/18639 0.133333333333333 1.95531077891424 0.272794222965319 0.726170537189369 GO:0048531 beta-1,3-galactosyltransferase activity 2/1271 15/18639 0.133333333333333 1.95531077891424 0.272794222965319 0.726170537189369 GO:0120283 protein serine/threonine kinase binding 2/1271 15/18639 0.133333333333333 1.95531077891424 0.272794222965319 0.726170537189369 GO:0141050 histone H3K deacetylase activity 2/1271 15/18639 0.133333333333333 1.95531077891424 0.272794222965319 0.726170537189369 GO:0141051 histone H4K deacetylase activity 2/1271 15/18639 0.133333333333333 1.95531077891424 0.272794222965319 0.726170537189369 GO:0061135 endopeptidase regulator activity 15/1271 184/18639 0.0815217391304348 1.1955025142818 0.27365544809256 0.726229939194058 GO:0016776 phosphotransferase activity, phosphate group as acceptor 4/1271 39/18639 0.102564102564103 1.50408521454942 0.274097366821038 0.726229939194058 GO:0004364 glutathione transferase activity 3/1271 27/18639 0.111111111111111 1.6294256490952 0.278715562735396 0.733325865758558 GO:0008320 protein transmembrane transporter activity 3/1271 27/18639 0.111111111111111 1.6294256490952 0.278715562735396 0.733325865758558 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 3/1271 27/18639 0.111111111111111 1.6294256490952 0.278715562735396 0.733325865758558 GO:0061134 peptidase regulator activity 18/1271 226/18639 0.079646017699115 1.16799537678506 0.280830336828366 0.737179634174462 GO:0015036 disulfide oxidoreductase activity 4/1271 40/18639 0.1 1.46648308418568 0.289654894764718 0.758588107767183 GO:0005003 ephrin receptor activity 5/1271 53/18639 0.0943396226415094 1.38347460772234 0.293385262785692 0.759611567220294 GO:0005005 transmembrane-ephrin receptor activity 5/1271 53/18639 0.0943396226415094 1.38347460772234 0.293385262785692 0.759611567220294 GO:0034212 protein N-acetyltransferase activity 5/1271 53/18639 0.0943396226415094 1.38347460772234 0.293385262785692 0.759611567220294 GO:0019789 SUMO transferase activity 3/1271 28/18639 0.107142857142857 1.57123187591323 0.297767402843319 0.759611567220294 GO:0046625 sphingolipid binding 3/1271 28/18639 0.107142857142857 1.57123187591323 0.297767402843319 0.759611567220294 GO:0016741 transferase activity, transferring one-carbon groups 17/1271 215/18639 0.0790697674418605 1.15954476423984 0.298400940350654 0.759611567220294 GO:0000062 fatty-acyl-CoA binding 2/1271 16/18639 0.125 1.8331038552321 0.298753755714507 0.759611567220294 GO:0003688 DNA replication origin binding 2/1271 16/18639 0.125 1.8331038552321 0.298753755714507 0.759611567220294 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1271 16/18639 0.125 1.8331038552321 0.298753755714507 0.759611567220294 GO:0022858 alanine transmembrane transporter activity 2/1271 16/18639 0.125 1.8331038552321 0.298753755714507 0.759611567220294 GO:0030275 LRR domain binding 2/1271 16/18639 0.125 1.8331038552321 0.298753755714507 0.759611567220294 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/1271 16/18639 0.125 1.8331038552321 0.298753755714507 0.759611567220294 GO:0070411 I-SMAD binding 2/1271 16/18639 0.125 1.8331038552321 0.298753755714507 0.759611567220294 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 18/1271 229/18639 0.0786026200873362 1.15269412730752 0.29985793972278 0.760713430974569 GO:0032182 ubiquitin-like protein binding 10/1271 120/18639 0.0833333333333333 1.2220692368214 0.302157262484384 0.764835570663598 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/1271 41/18639 0.0975609756097561 1.43071520408359 0.305328104415331 0.769291332804712 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 6/1271 67/18639 0.0895522388059701 1.31326843359912 0.305952725833267 0.769291332804712 GO:0050840 extracellular matrix binding 6/1271 67/18639 0.0895522388059701 1.31326843359912 0.305952725833267 0.769291332804712 GO:0004540 RNA nuclease activity 10/1271 121/18639 0.0826446280991736 1.21196949106255 0.311132941028197 0.780585741429149 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 10/1271 122/18639 0.0819672131147541 1.2020353149063 0.320169557640749 0.791500475098176 GO:0004867 serine-type endopeptidase inhibitor activity 8/1271 95/18639 0.0842105263157895 1.23493312352478 0.321008931452284 0.791500475098176 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/1271 17/18639 0.117647058823529 1.72527421668904 0.324557073122268 0.791500475098176 GO:0008429 phosphatidylethanolamine binding 2/1271 17/18639 0.117647058823529 1.72527421668904 0.324557073122268 0.791500475098176 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/1271 17/18639 0.117647058823529 1.72527421668904 0.324557073122268 0.791500475098176 GO:0019198 transmembrane receptor protein phosphatase activity 2/1271 17/18639 0.117647058823529 1.72527421668904 0.324557073122268 0.791500475098176 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/1271 17/18639 0.117647058823529 1.72527421668904 0.324557073122268 0.791500475098176 GO:0032183 SUMO binding 2/1271 17/18639 0.117647058823529 1.72527421668904 0.324557073122268 0.791500475098176 GO:0032977 membrane insertase activity 2/1271 17/18639 0.117647058823529 1.72527421668904 0.324557073122268 0.791500475098176 GO:0046965 nuclear retinoid X receptor binding 2/1271 17/18639 0.117647058823529 1.72527421668904 0.324557073122268 0.791500475098176 GO:0051787 misfolded protein binding 2/1271 17/18639 0.117647058823529 1.72527421668904 0.324557073122268 0.791500475098176 GO:0070403 NAD+ binding 2/1271 17/18639 0.117647058823529 1.72527421668904 0.324557073122268 0.791500475098176 GO:1901567 fatty acid derivative binding 2/1271 17/18639 0.117647058823529 1.72527421668904 0.324557073122268 0.791500475098176 GO:0004620 phospholipase activity 9/1271 109/18639 0.0825688073394495 1.21085759244689 0.325708610237162 0.792604214611462 GO:0008080 N-acetyltransferase activity 6/1271 69/18639 0.0869565217391304 1.27520268190059 0.330412956181637 0.802330390385389 GO:0008106 alcohol dehydrogenase (NADP+) activity 3/1271 30/18639 0.1 1.46648308418568 0.336023414087703 0.812474523615043 GO:0033612 receptor serine/threonine kinase binding 3/1271 30/18639 0.1 1.46648308418568 0.336023414087703 0.812474523615043 GO:0030165 PDZ domain binding 7/1271 83/18639 0.0843373493975904 1.23679296256624 0.337068590904734 0.813267621459506 GO:0016853 isomerase activity 14/1271 180/18639 0.0777777777777778 1.14059795436664 0.344434764689122 0.821985246592793 GO:0004527 exonuclease activity 7/1271 84/18639 0.0833333333333333 1.2220692368214 0.348340469781507 0.821985246592793 GO:0008525 phosphatidylcholine transporter activity 2/1271 18/18639 0.111111111111111 1.6294256490952 0.350104827252486 0.821985246592793 GO:0015172 acidic amino acid transmembrane transporter activity 2/1271 18/18639 0.111111111111111 1.6294256490952 0.350104827252486 0.821985246592793 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/1271 18/18639 0.111111111111111 1.6294256490952 0.350104827252486 0.821985246592793 GO:0017075 syntaxin-1 binding 2/1271 18/18639 0.111111111111111 1.6294256490952 0.350104827252486 0.821985246592793 GO:0017128 phospholipid scramblase activity 2/1271 18/18639 0.111111111111111 1.6294256490952 0.350104827252486 0.821985246592793 GO:0035615 clathrin adaptor activity 2/1271 18/18639 0.111111111111111 1.6294256490952 0.350104827252486 0.821985246592793 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/1271 18/18639 0.111111111111111 1.6294256490952 0.350104827252486 0.821985246592793 GO:0070064 proline-rich region binding 2/1271 18/18639 0.111111111111111 1.6294256490952 0.350104827252486 0.821985246592793 GO:0070628 proteasome binding 2/1271 18/18639 0.111111111111111 1.6294256490952 0.350104827252486 0.821985246592793 GO:0098641 cadherin binding involved in cell-cell adhesion 2/1271 18/18639 0.111111111111111 1.6294256490952 0.350104827252486 0.821985246592793 GO:1990381 ubiquitin-specific protease binding 2/1271 18/18639 0.111111111111111 1.6294256490952 0.350104827252486 0.821985246592793 GO:0043014 alpha-tubulin binding 4/1271 44/18639 0.0909090909090909 1.3331664401688 0.352743452015846 0.826469162367706 GO:0047499 calcium-independent phospholipase A2 activity 3/1271 31/18639 0.0967741935483871 1.41917717824421 0.355129753771318 0.830344620158092 GO:0030246 carbohydrate binding 21/1271 280/18639 0.075 1.09986231313926 0.357383986556963 0.833895968632914 GO:0008408 3'-5' exonuclease activity 5/1271 58/18639 0.0862068965517241 1.26420955533248 0.361946578268368 0.841080778189198 GO:0017116 single-stranded DNA helicase activity 5/1271 58/18639 0.0862068965517241 1.26420955533248 0.361946578268368 0.841080778189198 GO:0046915 transition metal ion transmembrane transporter activity 4/1271 45/18639 0.0888888888888889 1.30354051927616 0.368586525687924 0.842139132780068 GO:0051539 4 iron, 4 sulfur cluster binding 4/1271 45/18639 0.0888888888888889 1.30354051927616 0.368586525687924 0.842139132780068 GO:0140303 intramembrane lipid transporter activity 4/1271 45/18639 0.0888888888888889 1.30354051927616 0.368586525687924 0.842139132780068 GO:0008378 galactosyltransferase activity 3/1271 32/18639 0.09375 1.37482789142408 0.37416202360248 0.842139132780068 GO:0022884 macromolecule transmembrane transporter activity 3/1271 32/18639 0.09375 1.37482789142408 0.37416202360248 0.842139132780068 GO:0031369 translation initiation factor binding 3/1271 32/18639 0.09375 1.37482789142408 0.37416202360248 0.842139132780068 GO:0042910 xenobiotic transmembrane transporter activity 3/1271 32/18639 0.09375 1.37482789142408 0.37416202360248 0.842139132780068 GO:0120015 sterol transfer activity 3/1271 32/18639 0.09375 1.37482789142408 0.37416202360248 0.842139132780068 GO:0003756 protein disulfide isomerase activity 2/1271 19/18639 0.105263157894737 1.54366640440598 0.375311925291751 0.842139132780068 GO:0008301 DNA binding, bending 2/1271 19/18639 0.105263157894737 1.54366640440598 0.375311925291751 0.842139132780068 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/1271 19/18639 0.105263157894737 1.54366640440598 0.375311925291751 0.842139132780068 GO:0042577 lipid phosphatase activity 2/1271 19/18639 0.105263157894737 1.54366640440598 0.375311925291751 0.842139132780068 GO:0043395 heparan sulfate proteoglycan binding 2/1271 19/18639 0.105263157894737 1.54366640440598 0.375311925291751 0.842139132780068 GO:0050145 nucleoside monophosphate kinase activity 2/1271 19/18639 0.105263157894737 1.54366640440598 0.375311925291751 0.842139132780068 GO:0070003 threonine-type peptidase activity 2/1271 19/18639 0.105263157894737 1.54366640440598 0.375311925291751 0.842139132780068 GO:0120227 acyl-CoA binding 2/1271 19/18639 0.105263157894737 1.54366640440598 0.375311925291751 0.842139132780068 GO:0004879 nuclear receptor activity 5/1271 59/18639 0.0847457627118644 1.24278227473363 0.375769313215798 0.842139132780068 GO:0031593 polyubiquitin modification-dependent protein binding 5/1271 59/18639 0.0847457627118644 1.24278227473363 0.375769313215798 0.842139132780068 GO:0008081 phosphoric diester hydrolase activity 7/1271 87/18639 0.0804597701149425 1.17992891831032 0.382356453145717 0.854817045119037 GO:0017124 SH3 domain binding 9/1271 115/18639 0.0782608695652174 1.14768241371053 0.384441528228138 0.854817045119037 GO:0035401 histone H3Y41 kinase activity 9/1271 115/18639 0.0782608695652174 1.14768241371053 0.384441528228138 0.854817045119037 GO:0140801 histone H2AXY142 kinase activity 9/1271 115/18639 0.0782608695652174 1.14768241371053 0.384441528228138 0.854817045119037 GO:0098531 ligand-modulated transcription factor activity 5/1271 60/18639 0.0833333333333333 1.2220692368214 0.389586989250546 0.862730650456802 GO:0031491 nucleosome binding 6/1271 74/18639 0.0810810810810811 1.18904033852893 0.392335537706177 0.862730650456802 GO:0035064 methylated histone binding 6/1271 74/18639 0.0810810810810811 1.18904033852893 0.392335537706177 0.862730650456802 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/1271 33/18639 0.0909090909090909 1.3331664401688 0.393079665442076 0.862730650456802 GO:0071889 14-3-3 protein binding 3/1271 33/18639 0.0909090909090909 1.3331664401688 0.393079665442076 0.862730650456802 GO:0019955 cytokine binding 11/1271 144/18639 0.0763888888888889 1.12023013375295 0.393389873271637 0.862730650456802 GO:0004197 cysteine-type endopeptidase activity 7/1271 88/18639 0.0795454545454545 1.1665206351477 0.393728584574914 0.862730650456802 GO:0001614 purinergic nucleotide receptor activity 2/1271 20/18639 0.1 1.46648308418568 0.400106049899421 0.862730650456802 GO:0010851 cyclase regulator activity 2/1271 20/18639 0.1 1.46648308418568 0.400106049899421 0.862730650456802 GO:0015095 magnesium ion transmembrane transporter activity 2/1271 20/18639 0.1 1.46648308418568 0.400106049899421 0.862730650456802 GO:0016502 nucleotide receptor activity 2/1271 20/18639 0.1 1.46648308418568 0.400106049899421 0.862730650456802 GO:0030742 GTP-dependent protein binding 2/1271 20/18639 0.1 1.46648308418568 0.400106049899421 0.862730650456802 GO:0061608 nuclear import signal receptor activity 2/1271 20/18639 0.1 1.46648308418568 0.400106049899421 0.862730650456802 GO:0140939 histone H4 methyltransferase activity 2/1271 20/18639 0.1 1.46648308418568 0.400106049899421 0.862730650456802 GO:0043495 protein-membrane adaptor activity 4/1271 47/18639 0.0851063829787234 1.24807070994526 0.400173123580492 0.862730650456802 GO:0140359 ABC-type transporter activity 4/1271 47/18639 0.0851063829787234 1.24807070994526 0.400173123580492 0.862730650456802 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 3/1271 34/18639 0.0882352941176471 1.29395566251678 0.411845385222189 0.876485131988478 GO:0051427 hormone receptor binding 3/1271 34/18639 0.0882352941176471 1.29395566251678 0.411845385222189 0.876485131988478 GO:0052866 phosphatidylinositol phosphate phosphatase activity 3/1271 34/18639 0.0882352941176471 1.29395566251678 0.411845385222189 0.876485131988478 GO:0004674 protein serine/threonine kinase activity 31/1271 433/18639 0.0715935334872979 1.04990705796203 0.415548644483224 0.876485131988478 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/1271 48/18639 0.0833333333333333 1.2220692368214 0.415868934010673 0.876485131988478 GO:0038187 pattern recognition receptor activity 4/1271 48/18639 0.0833333333333333 1.2220692368214 0.415868934010673 0.876485131988478 GO:0140034 methylation-dependent protein binding 6/1271 76/18639 0.0789473684210526 1.15774980330448 0.417140301042262 0.876485131988478 GO:0015179 L-amino acid transmembrane transporter activity 5/1271 62/18639 0.0806451612903226 1.18264764853684 0.417140710708627 0.876485131988478 GO:0005123 death receptor binding 2/1271 21/18639 0.0952380952380952 1.39665055636731 0.424426314820827 0.876485131988478 GO:0008373 sialyltransferase activity 2/1271 21/18639 0.0952380952380952 1.39665055636731 0.424426314820827 0.876485131988478 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/1271 21/18639 0.0952380952380952 1.39665055636731 0.424426314820827 0.876485131988478 GO:0140312 cargo adaptor activity 2/1271 21/18639 0.0952380952380952 1.39665055636731 0.424426314820827 0.876485131988478 GO:0004623 phospholipase A2 activity 3/1271 35/18639 0.0857142857142857 1.25698550073058 0.430425074234124 0.876485131988478 GO:0005154 epidermal growth factor receptor binding 3/1271 35/18639 0.0857142857142857 1.25698550073058 0.430425074234124 0.876485131988478 GO:0043015 gamma-tubulin binding 3/1271 35/18639 0.0857142857142857 1.25698550073058 0.430425074234124 0.876485131988478 GO:0005004 GPI-linked ephrin receptor activity 4/1271 49/18639 0.0816326530612245 1.19712904831484 0.431470129995394 0.876485131988478 GO:0005008 hepatocyte growth factor receptor activity 4/1271 49/18639 0.0816326530612245 1.19712904831484 0.431470129995394 0.876485131988478 GO:0005009 insulin receptor activity 4/1271 49/18639 0.0816326530612245 1.19712904831484 0.431470129995394 0.876485131988478 GO:0005011 macrophage colony-stimulating factor receptor activity 4/1271 49/18639 0.0816326530612245 1.19712904831484 0.431470129995394 0.876485131988478 GO:0005018 platelet-derived growth factor alpha-receptor activity 4/1271 49/18639 0.0816326530612245 1.19712904831484 0.431470129995394 0.876485131988478 GO:0005020 stem cell factor receptor activity 4/1271 49/18639 0.0816326530612245 1.19712904831484 0.431470129995394 0.876485131988478 GO:0008288 boss receptor activity 4/1271 49/18639 0.0816326530612245 1.19712904831484 0.431470129995394 0.876485131988478 GO:0036332 placental growth factor receptor activity 4/1271 49/18639 0.0816326530612245 1.19712904831484 0.431470129995394 0.876485131988478 GO:0038062 protein tyrosine kinase collagen receptor activity 4/1271 49/18639 0.0816326530612245 1.19712904831484 0.431470129995394 0.876485131988478 GO:0060175 brain-derived neurotrophic factor receptor activity 4/1271 49/18639 0.0816326530612245 1.19712904831484 0.431470129995394 0.876485131988478 GO:0000149 SNARE binding 8/1271 106/18639 0.0754716981132075 1.10677968617787 0.436471337243412 0.876485131988478 GO:0005006 epidermal growth factor receptor activity 4/1271 50/18639 0.08 1.17318646734854 0.446956151446995 0.876485131988478 GO:0005007 fibroblast growth factor receptor activity 4/1271 50/18639 0.08 1.17318646734854 0.446956151446995 0.876485131988478 GO:0005017 platelet-derived growth factor receptor activity 4/1271 50/18639 0.08 1.17318646734854 0.446956151446995 0.876485131988478 GO:0005019 platelet-derived growth factor beta-receptor activity 4/1271 50/18639 0.08 1.17318646734854 0.446956151446995 0.876485131988478 GO:0015605 organophosphate ester transmembrane transporter activity 4/1271 50/18639 0.08 1.17318646734854 0.446956151446995 0.876485131988478 GO:0004407 histone deacetylase activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0031683 G-protein beta/gamma-subunit complex binding 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0032931 histone H3K56 acetyltransferase activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0033558 protein lysine deacetylase activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0043992 histone H3K9 acetyltransferase activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0043993 histone H3K18 acetyltransferase activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0043994 histone H3K23 acetyltransferase activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0043999 histone H2AK5 acetyltransferase activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0044012 histone H2AK9 acetyltransferase activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0044014 histone H2BK5 acetyltransferase activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0044015 histone H2BK12 acetyltransferase activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0044016 histone H3K4 acetyltransferase activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0044017 histone H3K27 acetyltransferase activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0044018 histone H3K36 acetyltransferase activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0046972 histone H4K16 acetyltransferase activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0070034 telomerase RNA binding 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0140784 metal ion sensor activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0140908 histone H3K122 acetyltransferase activity 2/1271 22/18639 0.0909090909090909 1.3331664401688 0.448222044218589 0.876485131988478 GO:0004033 aldo-keto reductase (NADPH) activity 3/1271 36/18639 0.0833333333333333 1.2220692368214 0.448787713915525 0.876485131988478 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 3/1271 36/18639 0.0833333333333333 1.2220692368214 0.448787713915525 0.876485131988478 GO:0045505 dynein intermediate chain binding 3/1271 36/18639 0.0833333333333333 1.2220692368214 0.448787713915525 0.876485131988478 GO:0051219 phosphoprotein binding 7/1271 93/18639 0.0752688172043011 1.10380447196772 0.450413417929346 0.876485131988478 GO:0004518 nuclease activity 15/1271 209/18639 0.0717703349282297 1.0524998211859 0.457256228954476 0.876485131988478 GO:0016410 N-acyltransferase activity 7/1271 94/18639 0.074468085106383 1.0920618712021 0.461652983466337 0.876485131988478 GO:0005010 insulin-like growth factor receptor activity 4/1271 51/18639 0.0784313725490196 1.15018281112602 0.462307764307989 0.876485131988478 GO:0005030 neurotrophin receptor activity 4/1271 51/18639 0.0784313725490196 1.15018281112602 0.462307764307989 0.876485131988478 GO:0016597 amino acid binding 4/1271 51/18639 0.0784313725490196 1.15018281112602 0.462307764307989 0.876485131988478 GO:0022804 active transmembrane transporter activity 32/1271 457/18639 0.0700218818380744 1.02685905238385 0.464547188190654 0.876485131988478 GO:0019213 deacetylase activity 3/1271 37/18639 0.0810810810810811 1.18904033852893 0.466905267566857 0.876485131988478 GO:0008514 organic anion transmembrane transporter activity 19/1271 269/18639 0.0706319702602231 1.03580589589323 0.471148576482954 0.876485131988478 GO:0003887 DNA-directed DNA polymerase activity 2/1271 23/18639 0.0869565217391304 1.27520268190059 0.471451665120714 0.876485131988478 GO:0004602 glutathione peroxidase activity 2/1271 23/18639 0.0869565217391304 1.27520268190059 0.471451665120714 0.876485131988478 GO:0044013 histone H2B acetyltransferase activity 2/1271 23/18639 0.0869565217391304 1.27520268190059 0.471451665120714 0.876485131988478 GO:0140103 catalytic activity, acting on a glycoprotein 2/1271 23/18639 0.0869565217391304 1.27520268190059 0.471451665120714 0.876485131988478 GO:0008276 protein methyltransferase activity 7/1271 95/18639 0.0736842105263158 1.08056648308419 0.472840578512909 0.876485131988478 GO:0005201 extracellular matrix structural constituent 12/1271 168/18639 0.0714285714285714 1.04748791727549 0.47710512591473 0.876485131988478 GO:0005080 protein kinase C binding 4/1271 52/18639 0.0769230769230769 1.12806391091206 0.477507052384335 0.876485131988478 GO:0140767 enzyme-substrate adaptor activity 10/1271 139/18639 0.0719424460431655 1.05502380157243 0.477764452104727 0.876485131988478 GO:0004222 metalloendopeptidase activity 8/1271 110/18639 0.0727272727272727 1.06653315213504 0.478271575855694 0.876485131988478 GO:0004896 cytokine receptor activity 7/1271 96/18639 0.0729166666666667 1.06931058221873 0.483968412967043 0.876485131988478 GO:0016407 acetyltransferase activity 7/1271 96/18639 0.0729166666666667 1.06931058221873 0.483968412967043 0.876485131988478 GO:0005109 frizzled binding 3/1271 38/18639 0.0789473684210526 1.15774980330448 0.484752561981761 0.876485131988478 GO:0008173 RNA methyltransferase activity 5/1271 67/18639 0.0746268656716418 1.0943903613326 0.48484384781898 0.876485131988478 GO:0016500 protein-hormone receptor activity 5/1271 67/18639 0.0746268656716418 1.0943903613326 0.48484384781898 0.876485131988478 GO:0042054 histone methyltransferase activity 5/1271 67/18639 0.0746268656716418 1.0943903613326 0.48484384781898 0.876485131988478 GO:0038064 collagen receptor activity 4/1271 53/18639 0.0754716981132075 1.10677968617787 0.492537402555652 0.876485131988478 GO:0005315 phosphate transmembrane transporter activity 2/1271 24/18639 0.0833333333333333 1.2220692368214 0.494081703252994 0.876485131988478 GO:0005540 hyaluronic acid binding 2/1271 24/18639 0.0833333333333333 1.2220692368214 0.494081703252994 0.876485131988478 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/1271 24/18639 0.0833333333333333 1.2220692368214 0.494081703252994 0.876485131988478 GO:0043998 histone H2A acetyltransferase activity 2/1271 24/18639 0.0833333333333333 1.2220692368214 0.494081703252994 0.876485131988478 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/1271 24/18639 0.0833333333333333 1.2220692368214 0.494081703252994 0.876485131988478 GO:0005548 phospholipid transporter activity 5/1271 68/18639 0.0735294117647059 1.07829638543065 0.498073738852609 0.876485131988478 GO:0004519 endonuclease activity 9/1271 127/18639 0.0708661417322835 1.03923998091899 0.502263424347616 0.876485131988478 GO:0000217 DNA secondary structure binding 3/1271 39/18639 0.0769230769230769 1.12806391091206 0.502307161578488 0.876485131988478 GO:0008170 N-methyltransferase activity 7/1271 98/18639 0.0714285714285714 1.04748791727549 0.506015137449578 0.876485131988478 GO:0000182 rDNA binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0004955 prostaglandin receptor activity 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0005131 growth hormone receptor binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0005345 purine nucleobase transmembrane transporter activity 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0005528 FK506 binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0016868 intramolecular phosphotransferase activity 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0019911 structural constituent of myelin sheath 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0031434 mitogen-activated protein kinase kinase binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0032356 oxidized DNA binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0035256 G protein-coupled glutamate receptor binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0042166 acetylcholine binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0042975 peroxisome proliferator activated receptor binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0043208 glycosphingolipid binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0043295 glutathione binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0043422 protein kinase B binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0045322 unmethylated CpG binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0050308 sugar-phosphatase activity 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0050815 phosphoserine residue binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0051378 serotonin binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0051864 histone H3K36 demethylase activity 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0070513 death domain binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0098505 G-rich strand telomeric DNA binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0099122 RNA polymerase II C-terminal domain binding 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0140940 histone H2A methyltransferase activity 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0140999 histone H3K4 trimethyltransferase activity 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:1990259 histone H2AQ104 methyltransferase activity 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:1990757 ubiquitin ligase activator activity 1/1271 10/18639 0.1 1.46648308418568 0.506604410184364 0.876485131988478 GO:0051287 NAD binding 4/1271 54/18639 0.0740740740740741 1.08628376606347 0.507383484159767 0.876485131988478 GO:0016279 protein-lysine N-methyltransferase activity 5/1271 69/18639 0.072463768115942 1.06266890158383 0.511172237498779 0.876485131988478 GO:0000030 mannosyltransferase activity 2/1271 25/18639 0.08 1.17318646734854 0.516085873322994 0.876485131988478 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/1271 25/18639 0.08 1.17318646734854 0.516085873322994 0.876485131988478 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/1271 25/18639 0.08 1.17318646734854 0.516085873322994 0.876485131988478 GO:0004177 aminopeptidase activity 3/1271 40/18639 0.075 1.09986231313926 0.519549237266091 0.876485131988478 GO:0004532 RNA exonuclease activity 3/1271 40/18639 0.075 1.09986231313926 0.519549237266091 0.876485131988478 GO:0030331 nuclear estrogen receptor binding 3/1271 40/18639 0.075 1.09986231313926 0.519549237266091 0.876485131988478 GO:0035591 signaling adaptor activity 9/1271 129/18639 0.0697674418604651 1.0231277331528 0.521401565875492 0.876485131988478 GO:0098632 cell-cell adhesion mediator activity 4/1271 55/18639 0.0727272727272727 1.06653315213504 0.522031223297785 0.876485131988478 GO:0008028 monocarboxylic acid transmembrane transporter activity 5/1271 70/18639 0.0714285714285714 1.04748791727549 0.524128861515646 0.876485131988478 GO:0016278 lysine N-methyltransferase activity 5/1271 70/18639 0.0714285714285714 1.04748791727549 0.524128861515646 0.876485131988478 GO:0043130 ubiquitin binding 7/1271 100/18639 0.07 1.02653815892998 0.527736899641872 0.876485131988478 GO:0008168 methyltransferase activity 14/1271 204/18639 0.0686274509803922 1.00640995973527 0.53002980969217 0.876485131988478 GO:0016298 lipase activity 9/1271 130/18639 0.0692307692307692 1.01525751982086 0.530878891699846 0.876485131988478 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 9/1271 130/18639 0.0692307692307692 1.01525751982086 0.530878891699846 0.876485131988478 GO:0042169 SH2 domain binding 3/1271 41/18639 0.0731707317073171 1.07303640306269 0.536461431964836 0.876485131988478 GO:0061630 ubiquitin protein ligase activity 24/1271 353/18639 0.0679886685552408 0.997042323525675 0.536803595924797 0.876485131988478 GO:0140299 molecular sensor activity 5/1271 71/18639 0.0704225352112676 1.03273456632794 0.53693383997883 0.876485131988478 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/1271 26/18639 0.0769230769230769 1.12806391091206 0.537444255559044 0.876485131988478 GO:0005112 Notch binding 2/1271 26/18639 0.0769230769230769 1.12806391091206 0.537444255559044 0.876485131988478 GO:0030247 polysaccharide binding 2/1271 26/18639 0.0769230769230769 1.12806391091206 0.537444255559044 0.876485131988478 GO:0030507 spectrin binding 2/1271 26/18639 0.0769230769230769 1.12806391091206 0.537444255559044 0.876485131988478 GO:0052742 phosphatidylinositol kinase activity 2/1271 26/18639 0.0769230769230769 1.12806391091206 0.537444255559044 0.876485131988478 GO:0070006 metalloaminopeptidase activity 2/1271 26/18639 0.0769230769230769 1.12806391091206 0.537444255559044 0.876485131988478 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/1271 86/18639 0.0697674418604651 1.0231277331528 0.537633708738227 0.876485131988478 GO:0050660 flavin adenine dinucleotide binding 6/1271 86/18639 0.0697674418604651 1.0231277331528 0.537633708738227 0.876485131988478 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0000099 sulfur amino acid transmembrane transporter activity 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0001851 complement component C3b binding 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0002162 dystroglycan binding 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0004954 prostanoid receptor activity 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0005225 volume-sensitive anion channel activity 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0005536 D-glucose binding 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0008046 axon guidance receptor activity 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0008172 S-methyltransferase activity 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0008199 ferric iron binding 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0008526 phosphatidylinositol transfer activity 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0015205 nucleobase transmembrane transporter activity 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0015217 ADP transmembrane transporter activity 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0019203 carbohydrate phosphatase activity 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0019206 nucleoside kinase activity 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0019864 IgG binding 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0031731 CCR6 chemokine receptor binding 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0032794 GTPase activating protein binding 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0034056 estrogen response element binding 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0045294 alpha-catenin binding 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0050998 nitric-oxide synthase binding 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0140537 transcription regulator activator activity 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:0180030 inositol phosphate kinase activity 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:1900750 oligopeptide binding 1/1271 11/18639 0.0909090909090909 1.3331664401688 0.540267290352686 0.876485131988478 GO:1990782 protein tyrosine kinase binding 8/1271 117/18639 0.0683760683760684 1.00272347636628 0.549274253635917 0.889210215333679 GO:0004683 calcium/calmodulin-dependent protein kinase activity 2/1271 27/18639 0.0740740740740741 1.08628376606347 0.558142550984935 0.889210215333679 GO:0008266 poly(U) RNA binding 2/1271 27/18639 0.0740740740740741 1.08628376606347 0.558142550984935 0.889210215333679 GO:0015252 proton channel activity 2/1271 27/18639 0.0740740740740741 1.08628376606347 0.558142550984935 0.889210215333679 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/1271 27/18639 0.0740740740740741 1.08628376606347 0.558142550984935 0.889210215333679 GO:0005319 lipid transporter activity 12/1271 178/18639 0.0674157303370786 0.988640281473492 0.559246011415571 0.889210215333679 GO:0061659 ubiquitin-like protein ligase activity 25/1271 372/18639 0.0672043010752688 0.985539707114033 0.560398797739492 0.889210215333679 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/1271 43/18639 0.0697674418604651 1.0231277331528 0.569238292713856 0.889210215333679 GO:0000340 RNA 7-methylguanosine cap binding 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0005025 transforming growth factor beta receptor activity, type I 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0005026 transforming growth factor beta receptor activity, type II 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0005095 GTPase inhibitor activity 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0005527 macrolide binding 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0010853 cyclase activator activity 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0015166 polyol transmembrane transporter activity 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0016361 activin receptor activity, type I 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0016362 activin receptor activity, type II 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0017002 activin receptor activity 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0035497 cAMP response element binding 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0036009 protein-glutamine N-methyltransferase activity 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0042301 phosphate ion binding 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0045295 gamma-catenin binding 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0070410 co-SMAD binding 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0070679 inositol 1,4,5 trisphosphate binding 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0097371 MDM2/MDM4 family protein binding 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:1990817 poly(A) RNA polymerase activity 1/1271 12/18639 0.0833333333333333 1.2220692368214 0.571635138428794 0.889210215333679 GO:0004842 ubiquitin-protein transferase activity 30/1271 449/18639 0.066815144766147 0.97983279566972 0.574048131095688 0.891740521455493 GO:0019787 ubiquitin-like protein transferase activity 32/1271 479/18639 0.0668058455114822 0.979696423673106 0.575112314408103 0.892171497317084 GO:0036408 histone H3K14 acetyltransferase activity 2/1271 28/18639 0.0714285714285714 1.04748791727549 0.578171408534291 0.894822660016336 GO:0015459 potassium channel regulator activity 4/1271 59/18639 0.0677966101694915 0.994225819786902 0.578399479534369 0.894822660016336 GO:0016755 aminoacyltransferase activity 33/1271 496/18639 0.0665322580645161 0.975684310042892 0.585227285697241 0.896552796206592 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 11/1271 167/18639 0.0658682634730539 0.965946941679191 0.59186144584183 0.896552796206592 GO:0072341 modified amino acid binding 6/1271 91/18639 0.0659340659340659 0.96691192363891 0.593774952782922 0.896552796206592 GO:0003785 actin monomer binding 2/1271 29/18639 0.0689655172413793 1.01136764426599 0.597525817681779 0.896552796206592 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/1271 29/18639 0.0689655172413793 1.01136764426599 0.597525817681779 0.896552796206592 GO:0010484 histone H3 acetyltransferase activity 2/1271 29/18639 0.0689655172413793 1.01136764426599 0.597525817681779 0.896552796206592 GO:0035250 UDP-galactosyltransferase activity 2/1271 29/18639 0.0689655172413793 1.01136764426599 0.597525817681779 0.896552796206592 GO:0097472 cyclin-dependent protein kinase activity 2/1271 29/18639 0.0689655172413793 1.01136764426599 0.597525817681779 0.896552796206592 GO:0017022 myosin binding 5/1271 76/18639 0.0657894736842105 0.964791502753737 0.598390594301609 0.896552796206592 GO:0019888 protein phosphatase regulator activity 7/1271 107/18639 0.0654205607476635 0.959381456943903 0.600509302289511 0.896552796206592 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0004465 lipoprotein lipase activity 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0004535 poly(A)-specific ribonuclease activity 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0004993 G protein-coupled serotonin receptor activity 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0008253 5'-nucleotidase activity 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0030955 potassium ion binding 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0035673 oligopeptide transmembrane transporter activity 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0043560 insulin receptor substrate binding 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0045159 myosin II binding 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0046974 histone H3K9 methyltransferase activity 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0061459 L-arginine transmembrane transporter activity 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0070123 transforming growth factor beta receptor activity, type III 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0071837 HMG box domain binding 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0140333 glycerophospholipid flippase activity 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/1271 13/18639 0.0769230769230769 1.12806391091206 0.600864307863324 0.896552796206592 GO:0052689 carboxylic ester hydrolase activity 6/1271 92/18639 0.0652173913043478 0.956402011425444 0.604564138087998 0.900887953471472 GO:0000287 magnesium ion binding 15/1271 230/18639 0.0652173913043478 0.956402011425444 0.609281247396409 0.906190809326268 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 3/1271 46/18639 0.0652173913043478 0.956402011425444 0.615622588826285 0.906190809326268 GO:0015215 nucleotide transmembrane transporter activity 2/1271 30/18639 0.0666666666666667 0.97765538945712 0.616204560795642 0.906190809326268 GO:0031210 phosphatidylcholine binding 2/1271 30/18639 0.0666666666666667 0.97765538945712 0.616204560795642 0.906190809326268 GO:0043995 histone H4K5 acetyltransferase activity 2/1271 30/18639 0.0666666666666667 0.97765538945712 0.616204560795642 0.906190809326268 GO:0043996 histone H4K8 acetyltransferase activity 2/1271 30/18639 0.0666666666666667 0.97765538945712 0.616204560795642 0.906190809326268 GO:0043997 histone H4K12 acetyltransferase activity 2/1271 30/18639 0.0666666666666667 0.97765538945712 0.616204560795642 0.906190809326268 GO:0003779 actin binding 29/1271 443/18639 0.0654627539503386 0.960000213123809 0.618733705445187 0.906190809326268 GO:0005347 ATP transmembrane transporter activity 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0005545 1-phosphatidylinositol binding 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0008195 phosphatidate phosphatase activity 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0008474 palmitoyl-(protein) hydrolase activity 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0008494 translation activator activity 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0008559 ABC-type xenobiotic transporter activity 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0015926 glucosidase activity 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0019763 immunoglobulin receptor activity 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0019992 diacylglycerol binding 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0032036 myosin heavy chain binding 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0032454 histone H3K9 demethylase activity 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0042043 neurexin family protein binding 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0061665 SUMO ligase activity 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0098599 palmitoyl hydrolase activity 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0098821 BMP receptor activity 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:1990825 sequence-specific mRNA binding 1/1271 14/18639 0.0714285714285714 1.04748791727549 0.62810050805154 0.906190809326268 GO:0033293 monocarboxylic acid binding 5/1271 79/18639 0.0632911392405063 0.928153850750431 0.632967946337728 0.909221014371012 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/1271 31/18639 0.0645161290322581 0.946118118829471 0.634209719900768 0.909221014371012 GO:0005452 solute:inorganic anion antiporter activity 2/1271 31/18639 0.0645161290322581 0.946118118829471 0.634209719900768 0.909221014371012 GO:0017147 Wnt-protein binding 2/1271 31/18639 0.0645161290322581 0.946118118829471 0.634209719900768 0.909221014371012 GO:0072349 modified amino acid transmembrane transporter activity 2/1271 31/18639 0.0645161290322581 0.946118118829471 0.634209719900768 0.909221014371012 GO:0046943 carboxylic acid transmembrane transporter activity 12/1271 188/18639 0.0638297872340425 0.936053032458945 0.635995724358032 0.910630241694455 GO:0020037 heme binding 9/1271 142/18639 0.0633802816901408 0.92946110969515 0.638288126156566 0.912760069434484 GO:0005342 organic acid transmembrane transporter activity 12/1271 189/18639 0.0634920634920635 0.931100370911543 0.643283713839706 0.91408011424834 GO:0048306 calcium-dependent protein binding 5/1271 80/18639 0.0625 0.91655192761605 0.644079966202826 0.91408011424834 GO:0047498 calcium-dependent phospholipase A2 activity 2/1271 32/18639 0.0625 0.91655192761605 0.65154623298732 0.91408011424834 GO:0140142 nucleocytoplasmic carrier activity 2/1271 32/18639 0.0625 0.91655192761605 0.65154623298732 0.91408011424834 GO:0004089 carbonate dehydratase activity 1/1271 15/18639 0.0666666666666667 0.97765538945712 0.653479528414842 0.91408011424834 GO:0004559 alpha-mannosidase activity 1/1271 15/18639 0.0666666666666667 0.97765538945712 0.653479528414842 0.91408011424834 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/1271 15/18639 0.0666666666666667 0.97765538945712 0.653479528414842 0.91408011424834 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/1271 15/18639 0.0666666666666667 0.97765538945712 0.653479528414842 0.91408011424834 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1271 15/18639 0.0666666666666667 0.97765538945712 0.653479528414842 0.91408011424834 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/1271 15/18639 0.0666666666666667 0.97765538945712 0.653479528414842 0.91408011424834 GO:0008020 G protein-coupled photoreceptor activity 1/1271 15/18639 0.0666666666666667 0.97765538945712 0.653479528414842 0.91408011424834 GO:0008252 nucleotidase activity 1/1271 15/18639 0.0666666666666667 0.97765538945712 0.653479528414842 0.91408011424834 GO:0015929 hexosaminidase activity 1/1271 15/18639 0.0666666666666667 0.97765538945712 0.653479528414842 0.91408011424834 GO:0030553 cGMP binding 1/1271 15/18639 0.0666666666666667 0.97765538945712 0.653479528414842 0.91408011424834 GO:0031005 filamin binding 1/1271 15/18639 0.0666666666666667 0.97765538945712 0.653479528414842 0.91408011424834 GO:0034483 heparan sulfate sulfotransferase activity 1/1271 15/18639 0.0666666666666667 0.97765538945712 0.653479528414842 0.91408011424834 GO:0047372 monoacylglycerol lipase activity 1/1271 15/18639 0.0666666666666667 0.97765538945712 0.653479528414842 0.91408011424834 GO:0019903 protein phosphatase binding 9/1271 144/18639 0.0625 0.91655192761605 0.654830443707745 0.91408011424834 GO:0015101 organic cation transmembrane transporter activity 5/1271 81/18639 0.0617283950617284 0.905236471719556 0.654978929085193 0.91408011424834 GO:0120013 lipid transfer activity 4/1271 65/18639 0.0615384615384615 0.90245112872965 0.655332568680688 0.91408011424834 GO:0016763 pentosyltransferase activity 3/1271 49/18639 0.0612244897959184 0.897846786236131 0.658508882980624 0.917382153931237 GO:0106310 protein serine kinase activity 23/1271 361/18639 0.0637119113573407 0.934324402666777 0.663661329612 0.92180438612074 GO:0004866 endopeptidase inhibitor activity 10/1271 161/18639 0.062111801242236 0.910859058500423 0.665750928146851 0.92180438612074 GO:0042626 ATPase-coupled transmembrane transporter activity 6/1271 98/18639 0.0612244897959184 0.897846786236131 0.665846233265505 0.92180438612074 GO:0008083 growth factor activity 10/1271 162/18639 0.0617283950617284 0.905236471719556 0.673324397145668 0.92180438612074 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/1271 16/18639 0.0625 0.91655192761605 0.677127913261531 0.92180438612074 GO:0004708 MAP kinase kinase activity 1/1271 16/18639 0.0625 0.91655192761605 0.677127913261531 0.92180438612074 GO:0005024 transforming growth factor beta receptor activity 1/1271 16/18639 0.0625 0.91655192761605 0.677127913261531 0.92180438612074 GO:0005149 interleukin-1 receptor binding 1/1271 16/18639 0.0625 0.91655192761605 0.677127913261531 0.92180438612074 GO:0005159 insulin-like growth factor receptor binding 1/1271 16/18639 0.0625 0.91655192761605 0.677127913261531 0.92180438612074 GO:0005521 lamin binding 1/1271 16/18639 0.0625 0.91655192761605 0.677127913261531 0.92180438612074 GO:0008296 3'-5'-DNA exonuclease activity 1/1271 16/18639 0.0625 0.91655192761605 0.677127913261531 0.92180438612074 GO:0015562 efflux transmembrane transporter activity 1/1271 16/18639 0.0625 0.91655192761605 0.677127913261531 0.92180438612074 GO:0015923 mannosidase activity 1/1271 16/18639 0.0625 0.91655192761605 0.677127913261531 0.92180438612074 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1271 16/18639 0.0625 0.91655192761605 0.677127913261531 0.92180438612074 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/1271 16/18639 0.0625 0.91655192761605 0.677127913261531 0.92180438612074 GO:0055102 lipase inhibitor activity 1/1271 16/18639 0.0625 0.91655192761605 0.677127913261531 0.92180438612074 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/1271 16/18639 0.0625 0.91655192761605 0.677127913261531 0.92180438612074 GO:0140327 flippase activity 1/1271 16/18639 0.0625 0.91655192761605 0.677127913261531 0.92180438612074 GO:0140328 floppase activity 1/1271 16/18639 0.0625 0.91655192761605 0.677127913261531 0.92180438612074 GO:0008376 acetylgalactosaminyltransferase activity 2/1271 34/18639 0.0588235294117647 0.862637108344518 0.684245002296307 0.929262074974865 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/1271 34/18639 0.0588235294117647 0.862637108344518 0.684245002296307 0.929262074974865 GO:0005179 hormone activity 8/1271 132/18639 0.0606060606060606 0.8887776267792 0.685367770517769 0.929673506898505 GO:0140223 general transcription initiation factor activity 4/1271 68/18639 0.0588235294117647 0.862637108344518 0.690064440003374 0.930103381035824 GO:0019208 phosphatase regulator activity 7/1271 117/18639 0.0598290598290598 0.877383041820493 0.693327527340603 0.930103381035824 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/1271 52/18639 0.0576923076923077 0.846047933184046 0.697829701149543 0.930103381035824 GO:0030159 signaling receptor complex adaptor activity 3/1271 52/18639 0.0576923076923077 0.846047933184046 0.697829701149543 0.930103381035824 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/1271 17/18639 0.0588235294117647 0.862637108344518 0.699163590770235 0.930103381035824 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/1271 17/18639 0.0588235294117647 0.862637108344518 0.699163590770235 0.930103381035824 GO:0008484 sulfuric ester hydrolase activity 1/1271 17/18639 0.0588235294117647 0.862637108344518 0.699163590770235 0.930103381035824 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/1271 17/18639 0.0588235294117647 0.862637108344518 0.699163590770235 0.930103381035824 GO:0009881 photoreceptor activity 1/1271 17/18639 0.0588235294117647 0.862637108344518 0.699163590770235 0.930103381035824 GO:0030548 acetylcholine receptor regulator activity 1/1271 17/18639 0.0588235294117647 0.862637108344518 0.699163590770235 0.930103381035824 GO:0031489 myosin V binding 1/1271 17/18639 0.0588235294117647 0.862637108344518 0.699163590770235 0.930103381035824 GO:0036041 long-chain fatty acid binding 1/1271 17/18639 0.0588235294117647 0.862637108344518 0.699163590770235 0.930103381035824 GO:0038191 neuropilin binding 1/1271 17/18639 0.0588235294117647 0.862637108344518 0.699163590770235 0.930103381035824 GO:0045125 bioactive lipid receptor activity 1/1271 17/18639 0.0588235294117647 0.862637108344518 0.699163590770235 0.930103381035824 GO:0000175 3'-5'-RNA exonuclease activity 2/1271 35/18639 0.0571428571428571 0.837990333820389 0.699628028239469 0.930103381035824 GO:0010485 histone H4 acetyltransferase activity 2/1271 35/18639 0.0571428571428571 0.837990333820389 0.699628028239469 0.930103381035824 GO:0034061 DNA polymerase activity 2/1271 35/18639 0.0571428571428571 0.837990333820389 0.699628028239469 0.930103381035824 GO:0141003 histone H2AX kinase activity 22/1271 354/18639 0.0621468926553672 0.911373668137994 0.70585323123089 0.93728052015905 GO:0005544 calcium-dependent phospholipid binding 3/1271 53/18639 0.0566037735849057 0.830084764633404 0.710147239065176 0.939681410851703 GO:0051018 protein kinase A binding 3/1271 53/18639 0.0566037735849057 0.830084764633404 0.710147239065176 0.939681410851703 GO:1901505 carbohydrate derivative transmembrane transporter activity 3/1271 53/18639 0.0566037735849057 0.830084764633404 0.710147239065176 0.939681410851703 GO:0003730 mRNA 3'-UTR binding 16/1271 262/18639 0.0610687022900763 0.895562188815683 0.712491864924833 0.941685052243311 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/1271 36/18639 0.0555555555555556 0.8147128245476 0.71438334084676 0.942202419549209 GO:0046906 tetrapyrrole binding 9/1271 152/18639 0.0592105263157895 0.868312352478363 0.716464235369627 0.942202419549209 GO:0016247 channel regulator activity 10/1271 168/18639 0.0595238095238095 0.872906597729572 0.716586113881594 0.942202419549209 GO:0000400 four-way junction DNA binding 1/1271 18/18639 0.0555555555555556 0.8147128245476 0.719696459212456 0.942202419549209 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/1271 18/18639 0.0555555555555556 0.8147128245476 0.719696459212456 0.942202419549209 GO:0008409 5'-3' exonuclease activity 1/1271 18/18639 0.0555555555555556 0.8147128245476 0.719696459212456 0.942202419549209 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/1271 18/18639 0.0555555555555556 0.8147128245476 0.719696459212456 0.942202419549209 GO:0099602 neurotransmitter receptor regulator activity 1/1271 18/18639 0.0555555555555556 0.8147128245476 0.719696459212456 0.942202419549209 GO:0140996 histone H3 kinase activity 22/1271 357/18639 0.061624649859944 0.903715065884733 0.720361109126247 0.942202419549209 GO:0030414 peptidase inhibitor activity 10/1271 169/18639 0.0591715976331361 0.867741469932355 0.723423753318955 0.945118129336054 GO:0022829 wide pore channel activity 2/1271 37/18639 0.0540540540540541 0.792693559019287 0.728524945034183 0.948504348643816 GO:0030551 cyclic nucleotide binding 2/1271 37/18639 0.0540540540540541 0.792693559019287 0.728524945034183 0.948504348643816 GO:0042805 actinin binding 2/1271 37/18639 0.0540540540540541 0.792693559019287 0.728524945034183 0.948504348643816 GO:0141108 transporter regulator activity 10/1271 170/18639 0.0588235294117647 0.862637108344518 0.730152925749284 0.949533736008817 GO:0035173 histone kinase activity 22/1271 360/18639 0.0611111111111111 0.89618410700236 0.73443439431164 0.950394284582363 GO:0004497 monooxygenase activity 6/1271 106/18639 0.0566037735849057 0.830084764633404 0.73762074773219 0.950394284582363 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/1271 19/18639 0.0526315789473684 0.77183320220299 0.738828933319162 0.950394284582363 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/1271 19/18639 0.0526315789473684 0.77183320220299 0.738828933319162 0.950394284582363 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/1271 19/18639 0.0526315789473684 0.77183320220299 0.738828933319162 0.950394284582363 GO:0016918 retinal binding 1/1271 19/18639 0.0526315789473684 0.77183320220299 0.738828933319162 0.950394284582363 GO:0031420 alkali metal ion binding 1/1271 19/18639 0.0526315789473684 0.77183320220299 0.738828933319162 0.950394284582363 GO:0042800 histone H3K4 methyltransferase activity 1/1271 19/18639 0.0526315789473684 0.77183320220299 0.738828933319162 0.950394284582363 GO:0099589 serotonin receptor activity 1/1271 19/18639 0.0526315789473684 0.77183320220299 0.738828933319162 0.950394284582363 GO:0070851 growth factor receptor binding 8/1271 139/18639 0.0575539568345324 0.844019041257946 0.739195554675171 0.950394284582363 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 2/1271 38/18639 0.0526315789473684 0.77183320220299 0.742067855203762 0.951928673983107 GO:0042887 amide transmembrane transporter activity 2/1271 38/18639 0.0526315789473684 0.77183320220299 0.742067855203762 0.951928673983107 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 5/1271 91/18639 0.0549450549450549 0.805759936365759 0.7518458919919 0.961937688641293 GO:0003684 damaged DNA binding 4/1271 74/18639 0.0540540540540541 0.792693559019287 0.751863054742598 0.961937688641293 GO:0019902 phosphatase binding 11/1271 190/18639 0.0578947368421053 0.849016522423289 0.754908385095497 0.961937688641293 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/1271 39/18639 0.0512820512820513 0.752042607274708 0.75502789269702 0.961937688641293 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/1271 20/18639 0.05 0.73324154209284 0.756656453499148 0.961937688641293 GO:0015464 acetylcholine receptor activity 1/1271 20/18639 0.05 0.73324154209284 0.756656453499148 0.961937688641293 GO:0016505 peptidase activator activity involved in apoptotic process 1/1271 20/18639 0.05 0.73324154209284 0.756656453499148 0.961937688641293 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/1271 20/18639 0.05 0.73324154209284 0.756656453499148 0.961937688641293 GO:0019003 GDP binding 4/1271 75/18639 0.0533333333333333 0.782124311565696 0.761181185550464 0.966606343129033 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/1271 40/18639 0.05 0.73324154209284 0.767421506140753 0.967865195508934 GO:0050997 quaternary ammonium group binding 2/1271 40/18639 0.05 0.73324154209284 0.767421506140753 0.967865195508934 GO:0071949 FAD binding 2/1271 40/18639 0.05 0.73324154209284 0.767421506140753 0.967865195508934 GO:0001846 opsonin binding 1/1271 21/18639 0.0476190476190476 0.698325278183657 0.773267960433064 0.967865195508934 GO:0015125 bile acid transmembrane transporter activity 1/1271 21/18639 0.0476190476190476 0.698325278183657 0.773267960433064 0.967865195508934 GO:0015174 basic amino acid transmembrane transporter activity 1/1271 21/18639 0.0476190476190476 0.698325278183657 0.773267960433064 0.967865195508934 GO:0036122 BMP binding 1/1271 21/18639 0.0476190476190476 0.698325278183657 0.773267960433064 0.967865195508934 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/1271 21/18639 0.0476190476190476 0.698325278183657 0.773267960433064 0.967865195508934 GO:0051010 microtubule plus-end binding 1/1271 21/18639 0.0476190476190476 0.698325278183657 0.773267960433064 0.967865195508934 GO:0051428 peptide hormone receptor binding 1/1271 21/18639 0.0476190476190476 0.698325278183657 0.773267960433064 0.967865195508934 GO:0061891 calcium ion sensor activity 1/1271 21/18639 0.0476190476190476 0.698325278183657 0.773267960433064 0.967865195508934 GO:0072542 protein phosphatase activator activity 1/1271 21/18639 0.0476190476190476 0.698325278183657 0.773267960433064 0.967865195508934 GO:1904047 S-adenosyl-L-methionine binding 1/1271 21/18639 0.0476190476190476 0.698325278183657 0.773267960433064 0.967865195508934 GO:1902936 phosphatidylinositol bisphosphate binding 6/1271 111/18639 0.0540540540540541 0.792693559019287 0.776514188554796 0.968955268185221 GO:0042562 hormone binding 5/1271 94/18639 0.0531914893617021 0.780044193715788 0.77658315283814 0.968955268185221 GO:0001727 lipid kinase activity 2/1271 41/18639 0.0487804878048781 0.715357602041795 0.779265612508749 0.968955268185221 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 2/1271 41/18639 0.0487804878048781 0.715357602041795 0.779265612508749 0.968955268185221 GO:0017080 sodium channel regulator activity 2/1271 41/18639 0.0487804878048781 0.715357602041795 0.779265612508749 0.968955268185221 GO:0140828 metal cation:monoatomic cation antiporter activity 2/1271 41/18639 0.0487804878048781 0.715357602041795 0.779265612508749 0.968955268185221 GO:0005543 phospholipid binding 30/1271 497/18639 0.0603621730382294 0.885201056852523 0.783156904657409 0.971449465056209 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/1271 60/18639 0.05 0.73324154209284 0.785709870511185 0.971449465056209 GO:0005243 gap junction channel activity 1/1271 22/18639 0.0454545454545455 0.6665832200844 0.788746337395658 0.971449465056209 GO:0008970 phospholipase A1 activity 1/1271 22/18639 0.0454545454545455 0.6665832200844 0.788746337395658 0.971449465056209 GO:0015377 chloride:monoatomic cation symporter activity 1/1271 22/18639 0.0454545454545455 0.6665832200844 0.788746337395658 0.971449465056209 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/1271 22/18639 0.0454545454545455 0.6665832200844 0.788746337395658 0.971449465056209 GO:0034062 5'-3' RNA polymerase activity 1/1271 22/18639 0.0454545454545455 0.6665832200844 0.788746337395658 0.971449465056209 GO:0097747 RNA polymerase activity 1/1271 22/18639 0.0454545454545455 0.6665832200844 0.788746337395658 0.971449465056209 GO:0031492 nucleosomal DNA binding 2/1271 42/18639 0.0476190476190476 0.698325278183657 0.790577456913108 0.971449465056209 GO:0048487 beta-tubulin binding 2/1271 42/18639 0.0476190476190476 0.698325278183657 0.790577456913108 0.971449465056209 GO:0016798 hydrolase activity, acting on glycosyl bonds 7/1271 130/18639 0.0538461538461538 0.789644737638443 0.791162413687402 0.971449465056209 GO:0016758 hexosyltransferase activity 11/1271 197/18639 0.0558375634517767 0.818848422641751 0.7944262627863 0.971449465056209 GO:0004677 DNA-dependent protein kinase activity 14/1271 246/18639 0.0569105691056911 0.834583869048761 0.794866467833895 0.971449465056209 GO:0008200 ion channel inhibitor activity 2/1271 43/18639 0.0465116279069767 0.6820851554352 0.801374489313072 0.971449465056209 GO:0008375 acetylglucosaminyltransferase activity 2/1271 43/18639 0.0465116279069767 0.6820851554352 0.801374489313072 0.971449465056209 GO:0000295 adenine nucleotide transmembrane transporter activity 1/1271 23/18639 0.0434782608695652 0.637601340950296 0.803168822499065 0.971449465056209 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/1271 23/18639 0.0434782608695652 0.637601340950296 0.803168822499065 0.971449465056209 GO:0005283 amino acid:sodium symporter activity 1/1271 23/18639 0.0434782608695652 0.637601340950296 0.803168822499065 0.971449465056209 GO:0017134 fibroblast growth factor binding 1/1271 23/18639 0.0434782608695652 0.637601340950296 0.803168822499065 0.971449465056209 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/1271 23/18639 0.0434782608695652 0.637601340950296 0.803168822499065 0.971449465056209 GO:0000049 tRNA binding 4/1271 80/18639 0.05 0.73324154209284 0.803727836868836 0.971449465056209 GO:0015294 solute:monoatomic cation symporter activity 6/1271 116/18639 0.0517241379310345 0.75852573319949 0.810908013021279 0.971449465056209 GO:0030971 receptor tyrosine kinase binding 4/1271 81/18639 0.0493827160493827 0.724189177375645 0.811455052857596 0.971449465056209 GO:0016248 channel inhibitor activity 2/1271 44/18639 0.0454545454545455 0.6665832200844 0.811674256489 0.971449465056209 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/1271 44/18639 0.0454545454545455 0.6665832200844 0.811674256489 0.971449465056209 GO:0008237 metallopeptidase activity 10/1271 184/18639 0.0543478260869565 0.79700167618787 0.812874043494179 0.971449465056209 GO:0016757 glycosyltransferase activity 15/1271 267/18639 0.0561797752808989 0.82386690122791 0.816285740378931 0.971449465056209 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/1271 24/18639 0.0416666666666667 0.6110346184107 0.816607392901068 0.971449465056209 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/1271 24/18639 0.0416666666666667 0.6110346184107 0.816607392901068 0.971449465056209 GO:0004622 lysophospholipase activity 1/1271 24/18639 0.0416666666666667 0.6110346184107 0.816607392901068 0.971449465056209 GO:0004806 triacylglycerol lipase activity 1/1271 24/18639 0.0416666666666667 0.6110346184107 0.816607392901068 0.971449465056209 GO:0015295 solute:proton symporter activity 1/1271 24/18639 0.0416666666666667 0.6110346184107 0.816607392901068 0.971449465056209 GO:0019957 C-C chemokine binding 1/1271 24/18639 0.0416666666666667 0.6110346184107 0.816607392901068 0.971449465056209 GO:0030215 semaphorin receptor binding 1/1271 24/18639 0.0416666666666667 0.6110346184107 0.816607392901068 0.971449465056209 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/1271 24/18639 0.0416666666666667 0.6110346184107 0.816607392901068 0.971449465056209 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/1271 24/18639 0.0416666666666667 0.6110346184107 0.816607392901068 0.971449465056209 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/1271 24/18639 0.0416666666666667 0.6110346184107 0.816607392901068 0.971449465056209 GO:0050431 transforming growth factor beta binding 1/1271 24/18639 0.0416666666666667 0.6110346184107 0.816607392901068 0.971449465056209 GO:1901981 phosphatidylinositol phosphate binding 10/1271 185/18639 0.0540540540540541 0.792693559019287 0.817970395105634 0.971449465056209 GO:0141110 transporter inhibitor activity 2/1271 45/18639 0.0444444444444444 0.65177025963808 0.821494307775561 0.971449465056209 GO:0160215 deacylase activity 3/1271 65/18639 0.0461538461538462 0.676838346547237 0.829069312167589 0.971449465056209 GO:0001848 complement binding 1/1271 25/18639 0.04 0.586593233674272 0.829129122883487 0.971449465056209 GO:0003707 nuclear steroid receptor activity 1/1271 25/18639 0.04 0.586593233674272 0.829129122883487 0.971449465056209 GO:0005537 D-mannose binding 1/1271 25/18639 0.04 0.586593233674272 0.829129122883487 0.971449465056209 GO:0008483 transaminase activity 1/1271 25/18639 0.04 0.586593233674272 0.829129122883487 0.971449465056209 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/1271 25/18639 0.04 0.586593233674272 0.829129122883487 0.971449465056209 GO:0015662 P-type ion transporter activity 1/1271 25/18639 0.04 0.586593233674272 0.829129122883487 0.971449465056209 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/1271 25/18639 0.04 0.586593233674272 0.829129122883487 0.971449465056209 GO:0017025 TBP-class protein binding 1/1271 25/18639 0.04 0.586593233674272 0.829129122883487 0.971449465056209 GO:0019211 phosphatase activator activity 1/1271 25/18639 0.04 0.586593233674272 0.829129122883487 0.971449465056209 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/1271 25/18639 0.04 0.586593233674272 0.829129122883487 0.971449465056209 GO:0019707 protein-cysteine S-acyltransferase activity 1/1271 25/18639 0.04 0.586593233674272 0.829129122883487 0.971449465056209 GO:0140358 P-type transmembrane transporter activity 1/1271 25/18639 0.04 0.586593233674272 0.829129122883487 0.971449465056209 GO:0004180 carboxypeptidase activity 2/1271 46/18639 0.0434782608695652 0.637601340950296 0.830852113182347 0.971449465056209 GO:0030276 clathrin binding 2/1271 46/18639 0.0434782608695652 0.637601340950296 0.830852113182347 0.971449465056209 GO:0008238 exopeptidase activity 5/1271 102/18639 0.0490196078431373 0.718864256953765 0.833252574076795 0.971449465056209 GO:0015171 amino acid transmembrane transporter activity 5/1271 102/18639 0.0490196078431373 0.718864256953765 0.833252574076795 0.971449465056209 GO:0046982 protein heterodimerization activity 21/1271 369/18639 0.0569105691056911 0.834583869048761 0.834478346141021 0.971449465056209 GO:0008235 metalloexopeptidase activity 3/1271 66/18639 0.0454545454545455 0.6665832200844 0.83677770147467 0.971449465056209 GO:0005504 fatty acid binding 2/1271 47/18639 0.0425531914893617 0.62403535497263 0.839764992652982 0.971449465056209 GO:0140938 histone H3 methyltransferase activity 2/1271 47/18639 0.0425531914893617 0.62403535497263 0.839764992652982 0.971449465056209 GO:0004529 DNA exonuclease activity 1/1271 26/18639 0.0384615384615385 0.564031955456031 0.840796517576465 0.971449465056209 GO:0015216 purine nucleotide transmembrane transporter activity 1/1271 26/18639 0.0384615384615385 0.564031955456031 0.840796517576465 0.971449465056209 GO:0019865 immunoglobulin binding 1/1271 26/18639 0.0384615384615385 0.564031955456031 0.840796517576465 0.971449465056209 GO:0051139 metal cation:proton antiporter activity 1/1271 26/18639 0.0384615384615385 0.564031955456031 0.840796517576465 0.971449465056209 GO:0120014 phospholipid transfer activity 1/1271 26/18639 0.0384615384615385 0.564031955456031 0.840796517576465 0.971449465056209 GO:0140101 catalytic activity, acting on a tRNA 7/1271 139/18639 0.0503597122302158 0.738516661100702 0.843754347138294 0.971449465056209 GO:0004175 endopeptidase activity 23/1271 405/18639 0.0567901234567901 0.832817553981992 0.846659410035416 0.971449465056209 GO:0008395 steroid hydroxylase activity 1/1271 27/18639 0.037037037037037 0.543141883031733 0.851667823983831 0.971449465056209 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 13/1271 243/18639 0.0534979423868313 0.784538275490282 0.852725601019456 0.971449465056209 GO:0004676 3-phosphoinositide-dependent protein kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0004711 ribosomal protein S6 kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0035175 histone H3S10 kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0035979 histone H2AXS139 kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0044022 histone H3S28 kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0044023 histone H4S1 kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0044024 histone H2AS1 kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0044025 histone H2BS14 kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0072354 histone H3T3 kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0072371 histone H2AS121 kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0072518 Rho-dependent protein serine/threonine kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0140823 histone H2BS36 kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0140855 histone H3S57 kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0140995 histone H2A kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0140997 histone H4 kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0140998 histone H2B kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:1990244 histone H2AT120 kinase activity 13/1271 245/18639 0.0530612244897959 0.778133881404647 0.86025048442379 0.971449465056209 GO:0099106 ion channel regulator activity 8/1271 160/18639 0.05 0.73324154209284 0.861136407140038 0.971449465056209 GO:0005242 inward rectifier potassium channel activity 1/1271 28/18639 0.0357142857142857 0.523743958637743 0.861797320852333 0.971449465056209 GO:0016866 intramolecular transferase activity 1/1271 28/18639 0.0357142857142857 0.523743958637743 0.861797320852333 0.971449465056209 GO:0045499 chemorepellent activity 1/1271 28/18639 0.0357142857142857 0.523743958637743 0.861797320852333 0.971449465056209 GO:0050698 proteoglycan sulfotransferase activity 1/1271 28/18639 0.0357142857142857 0.523743958637743 0.861797320852333 0.971449465056209 GO:0051393 alpha-actinin binding 1/1271 28/18639 0.0357142857142857 0.523743958637743 0.861797320852333 0.971449465056209 GO:0051959 dynein light intermediate chain binding 1/1271 28/18639 0.0357142857142857 0.523743958637743 0.861797320852333 0.971449465056209 GO:0140857 histone H3T45 kinase activity 13/1271 246/18639 0.0528455284552846 0.774970735545278 0.86389851968417 0.971747138051216 GO:0035402 histone H3T11 kinase activity 13/1271 247/18639 0.0526315789473684 0.77183320220299 0.867471328809787 0.971747138051216 GO:0035403 histone H3T6 kinase activity 13/1271 247/18639 0.0526315789473684 0.77183320220299 0.867471328809787 0.971747138051216 GO:0004679 AMP-activated protein kinase activity 13/1271 248/18639 0.0524193548387097 0.768720971548945 0.870969722735663 0.971747138051216 GO:0004181 metallocarboxypeptidase activity 1/1271 29/18639 0.0344827586206897 0.505683822132993 0.87123558882271 0.971747138051216 GO:0005416 amino acid:monoatomic cation symporter activity 1/1271 29/18639 0.0344827586206897 0.505683822132993 0.87123558882271 0.971747138051216 GO:0016417 S-acyltransferase activity 1/1271 29/18639 0.0344827586206897 0.505683822132993 0.87123558882271 0.971747138051216 GO:0043236 laminin binding 1/1271 29/18639 0.0344827586206897 0.505683822132993 0.87123558882271 0.971747138051216 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/1271 29/18639 0.0344827586206897 0.505683822132993 0.87123558882271 0.971747138051216 GO:0106222 lncRNA binding 1/1271 29/18639 0.0344827586206897 0.505683822132993 0.87123558882271 0.971747138051216 GO:0051020 GTPase binding 17/1271 315/18639 0.053968253968254 0.791435315274812 0.871487512696726 0.971747138051216 GO:0015293 symporter activity 7/1271 146/18639 0.0479452054794521 0.70310832803423 0.876852920777069 0.975516862500635 GO:0001965 G-protein alpha-subunit binding 1/1271 30/18639 0.0333333333333333 0.48882769472856 0.880029762202954 0.975516862500635 GO:0016769 transferase activity, transferring nitrogenous groups 1/1271 30/18639 0.0333333333333333 0.48882769472856 0.880029762202954 0.975516862500635 GO:0031624 ubiquitin conjugating enzyme binding 1/1271 30/18639 0.0333333333333333 0.48882769472856 0.880029762202954 0.975516862500635 GO:0051721 protein phosphatase 2A binding 1/1271 30/18639 0.0333333333333333 0.48882769472856 0.880029762202954 0.975516862500635 GO:0070566 adenylyltransferase activity 1/1271 30/18639 0.0333333333333333 0.48882769472856 0.880029762202954 0.975516862500635 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/1271 73/18639 0.0410958904109589 0.602664281172198 0.882760488345322 0.976074286139592 GO:0004864 protein phosphatase inhibitor activity 2/1271 53/18639 0.0377358490566038 0.553389843088936 0.8848363017209 0.976074286139592 GO:0008146 sulfotransferase activity 2/1271 53/18639 0.0377358490566038 0.553389843088936 0.8848363017209 0.976074286139592 GO:0016251 RNA polymerase II general transcription initiation factor activity 2/1271 53/18639 0.0377358490566038 0.553389843088936 0.8848363017209 0.976074286139592 GO:0017046 peptide hormone binding 2/1271 53/18639 0.0377358490566038 0.553389843088936 0.8848363017209 0.976074286139592 GO:0008327 methyl-CpG binding 1/1271 31/18639 0.032258064516129 0.473059059414736 0.888223763613026 0.977908493142885 GO:0070273 phosphatidylinositol-4-phosphate binding 1/1271 31/18639 0.032258064516129 0.473059059414736 0.888223763613026 0.977908493142885 GO:0016874 ligase activity 8/1271 167/18639 0.0479041916167665 0.702506866675775 0.889714225905308 0.978599352256663 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/1271 54/18639 0.037037037037037 0.543141883031733 0.891096370296108 0.979169848755607 GO:0015106 bicarbonate transmembrane transporter activity 1/1271 32/18639 0.03125 0.458275963808025 0.895858522665469 0.983449723816691 GO:0008234 cysteine-type peptidase activity 9/1271 187/18639 0.0481283422459893 0.705793997736424 0.89777413361189 0.984599485025032 GO:0019212 phosphatase inhibitor activity 2/1271 56/18639 0.0357142857142857 0.523743958637743 0.902678462630956 0.987074359813259 GO:0019239 deaminase activity 1/1271 33/18639 0.0303030303030303 0.4443888133896 0.902972179767215 0.987074359813259 GO:0019956 chemokine binding 1/1271 33/18639 0.0303030303030303 0.4443888133896 0.902972179767215 0.987074359813259 GO:0008017 microtubule binding 14/1271 276/18639 0.0507246376811594 0.743868231108679 0.904374570866375 0.987074359813259 GO:0015297 antiporter activity 6/1271 135/18639 0.0444444444444444 0.65177025963808 0.905107642684556 0.987074359813259 GO:0005516 calmodulin binding 10/1271 207/18639 0.0483091787439614 0.708445934389218 0.905253381133853 0.987074359813259 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/1271 57/18639 0.0350877192982456 0.514555468135326 0.908028306961875 0.987726866708046 GO:0016779 nucleotidyltransferase activity 6/1271 136/18639 0.0441176470588235 0.646977831258388 0.90868793642436 0.987726866708046 GO:0008175 tRNA methyltransferase activity 1/1271 34/18639 0.0294117647058824 0.431318554172259 0.909600276054212 0.987726866708046 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/1271 34/18639 0.0294117647058824 0.431318554172259 0.909600276054212 0.987726866708046 GO:0015370 solute:sodium symporter activity 3/1271 79/18639 0.0379746835443038 0.556892310450258 0.912585525337157 0.987726866708046 GO:0016835 carbon-oxygen lyase activity 3/1271 79/18639 0.0379746835443038 0.556892310450258 0.912585525337157 0.987726866708046 GO:0005343 organic acid:sodium symporter activity 1/1271 35/18639 0.0285714285714286 0.418995166910194 0.915775930401704 0.987726866708046 GO:0061631 ubiquitin conjugating enzyme activity 1/1271 35/18639 0.0285714285714286 0.418995166910194 0.915775930401704 0.987726866708046 GO:0140566 histone reader activity 1/1271 35/18639 0.0285714285714286 0.418995166910194 0.915775930401704 0.987726866708046 GO:0001786 phosphatidylserine binding 2/1271 59/18639 0.0338983050847458 0.497112909893451 0.917911743401797 0.987726866708046 GO:0015631 tubulin binding 20/1271 385/18639 0.051948051948052 0.761809394382172 0.920769920025088 0.987726866708046 GO:0031267 small GTPase binding 14/1271 283/18639 0.049469964664311 0.725468663554754 0.921416599012318 0.987726866708046 GO:0004190 aspartic-type endopeptidase activity 1/1271 36/18639 0.0277777777777778 0.4073564122738 0.921530004388988 0.987726866708046 GO:0005484 SNAP receptor activity 1/1271 36/18639 0.0277777777777778 0.4073564122738 0.921530004388988 0.987726866708046 GO:0016409 palmitoyltransferase activity 1/1271 36/18639 0.0277777777777778 0.4073564122738 0.921530004388988 0.987726866708046 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/1271 36/18639 0.0277777777777778 0.4073564122738 0.921530004388988 0.987726866708046 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/1271 36/18639 0.0277777777777778 0.4073564122738 0.921530004388988 0.987726866708046 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/1271 36/18639 0.0277777777777778 0.4073564122738 0.921530004388988 0.987726866708046 GO:0035091 phosphatidylinositol binding 14/1271 284/18639 0.0492957746478873 0.722914196429561 0.923629826952895 0.989042704215848 GO:0030280 structural constituent of skin epidermis 1/1271 37/18639 0.027027027027027 0.396346779509643 0.926891256037733 0.989963662668471 GO:0070001 aspartic-type peptidase activity 1/1271 37/18639 0.027027027027027 0.396346779509643 0.926891256037733 0.989963662668471 GO:0005253 monoatomic anion channel activity 4/1271 103/18639 0.0388349514563107 0.569507993858517 0.927108826943489 0.989963662668471 GO:0015291 secondary active transmembrane transporter activity 14/1271 287/18639 0.0487804878048781 0.715357602041795 0.929957055483737 0.991331399456846 GO:0000146 microfilament motor activity 1/1271 38/18639 0.0263157894736842 0.385916601101495 0.9318864830873 0.991331399456846 GO:0005501 retinoid binding 1/1271 38/18639 0.0263157894736842 0.385916601101495 0.9318864830873 0.991331399456846 GO:0019840 isoprenoid binding 1/1271 38/18639 0.0263157894736842 0.385916601101495 0.9318864830873 0.991331399456846 GO:0005507 copper ion binding 2/1271 63/18639 0.0317460317460317 0.465550185455772 0.93475541263907 0.992163197341972 GO:1901682 sulfur compound transmembrane transporter activity 2/1271 63/18639 0.0317460317460317 0.465550185455772 0.93475541263907 0.992163197341972 GO:0008194 UDP-glycosyltransferase activity 6/1271 145/18639 0.0413793103448276 0.606820586559592 0.935968743277145 0.992163197341972 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/1271 39/18639 0.0256410256410256 0.376021303637354 0.936540656518623 0.992163197341972 GO:0004536 DNA nuclease activity 2/1271 64/18639 0.03125 0.458275963808025 0.938423306813317 0.992163197341972 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/1271 40/18639 0.025 0.36662077104642 0.94087704498985 0.992163197341972 GO:0061791 GTPase motor activity 1/1271 40/18639 0.025 0.36662077104642 0.94087704498985 0.992163197341972 GO:0071855 neuropeptide receptor binding 1/1271 40/18639 0.025 0.36662077104642 0.94087704498985 0.992163197341972 GO:1990606 membrane scission GTPase motor activity 1/1271 40/18639 0.025 0.36662077104642 0.94087704498985 0.992163197341972 GO:0005496 steroid binding 4/1271 108/18639 0.037037037037037 0.543141883031733 0.942160745417866 0.992163197341972 GO:0004812 aminoacyl-tRNA ligase activity 1/1271 41/18639 0.024390243902439 0.357678801020898 0.944917330801878 0.992163197341972 GO:0008227 G protein-coupled amine receptor activity 1/1271 41/18639 0.024390243902439 0.357678801020898 0.944917330801878 0.992163197341972 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/1271 41/18639 0.024390243902439 0.357678801020898 0.944917330801878 0.992163197341972 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/1271 41/18639 0.024390243902439 0.357678801020898 0.944917330801878 0.992163197341972 GO:0004520 DNA endonuclease activity 1/1271 42/18639 0.0238095238095238 0.349162639091829 0.948681717969897 0.994274554693034 GO:0016859 cis-trans isomerase activity 1/1271 42/18639 0.0238095238095238 0.349162639091829 0.948681717969897 0.994274554693034 GO:0003777 microtubule motor activity 2/1271 68/18639 0.0294117647058824 0.431318554172259 0.951226413208757 0.996021008844627 GO:0005245 voltage-gated calcium channel activity 1/1271 43/18639 0.0232558139534884 0.3410425777176 0.952189032937916 0.996109191283761 GO:0043178 alcohol binding 3/1271 92/18639 0.0326086956521739 0.478201005712722 0.954932578610323 0.997686954058241 GO:0016790 thiolester hydrolase activity 1/1271 44/18639 0.0227272727272727 0.3332916100422 0.955456818436728 0.997686954058241 GO:0016782 transferase activity, transferring sulphur-containing groups 2/1271 70/18639 0.0285714285714286 0.418995166910194 0.956632816972387 0.997995965452334 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/1271 45/18639 0.0222222222222222 0.32588512981904 0.958501420951755 0.998938723840611 GO:0044325 transmembrane transporter binding 5/1271 136/18639 0.0367647058823529 0.539148192715324 0.95929829829138 0.998938723840611 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/1271 46/18639 0.0217391304347826 0.318800670475148 0.961338072235519 0.999998854294555 GO:0099095 ligand-gated monoatomic anion channel activity 1/1271 47/18639 0.0212765957446809 0.312017677486315 0.963980965269922 0.999998854294555 GO:0032266 phosphatidylinositol-3-phosphate binding 1/1271 48/18639 0.0208333333333333 0.30551730920535 0.966443325055956 0.999998854294555 GO:0015103 inorganic anion transmembrane transporter activity 6/1271 165/18639 0.0363636363636364 0.53326657606752 0.972346489318277 0.999998854294555 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/1271 53/18639 0.0188679245283019 0.276694921544468 0.976450187184533 0.999998854294555 GO:0008509 monoatomic anion transmembrane transporter activity 5/1271 149/18639 0.0335570469798658 0.492108417511973 0.977567598963931 0.999998854294555 GO:0015485 cholesterol binding 1/1271 54/18639 0.0185185185185185 0.271570941515867 0.978060636559787 0.999998854294555 GO:0050661 NADP binding 1/1271 54/18639 0.0185185185185185 0.271570941515867 0.978060636559787 0.999998854294555 GO:0005254 chloride channel activity 2/1271 83/18639 0.0240963855421687 0.353369417876068 0.980058078979943 0.999998854294555 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/1271 56/18639 0.0178571428571429 0.261871979318872 0.980958901372258 0.999998854294555 GO:0004252 serine-type endopeptidase activity 6/1271 176/18639 0.0340909090909091 0.4999374150633 0.983023884827806 0.999998854294555 GO:0099094 ligand-gated monoatomic cation channel activity 4/1271 136/18639 0.0294117647058824 0.431318554172259 0.985379078693123 0.999998854294555 GO:0016836 hydro-lyase activity 1/1271 61/18639 0.0163934426229508 0.240407062981259 0.986639216571886 0.999998854294555 GO:0022824 transmitter-gated monoatomic ion channel activity 1/1271 63/18639 0.0158730158730159 0.232775092727886 0.988404863175138 0.999998854294555 GO:0022835 transmitter-gated channel activity 1/1271 63/18639 0.0158730158730159 0.232775092727886 0.988404863175138 0.999998854294555 GO:0015081 sodium ion transmembrane transporter activity 5/1271 164/18639 0.0304878048780488 0.447098501276122 0.989057184573237 0.999998854294555 GO:0015108 chloride transmembrane transporter activity 3/1271 121/18639 0.0247933884297521 0.363590847318764 0.990687673418453 0.999998854294555 GO:0008528 G protein-coupled peptide receptor activity 3/1271 122/18639 0.0245901639344262 0.360610594471889 0.991197482299111 0.999998854294555 GO:0030594 neurotransmitter receptor activity 2/1271 97/18639 0.0206185567010309 0.302367646223852 0.991541623151677 0.999998854294555 GO:0032934 sterol binding 1/1271 68/18639 0.0147058823529412 0.21565927708613 0.991865034608689 0.999998854294555 GO:0098960 postsynaptic neurotransmitter receptor activity 1/1271 69/18639 0.0144927536231884 0.212533780316765 0.992421791972986 0.999998854294555 GO:0008236 serine-type peptidase activity 6/1271 194/18639 0.0309278350515464 0.453551469335778 0.992617506498402 0.999998854294555 GO:0001653 peptide receptor activity 3/1271 128/18639 0.0234375 0.343706972856019 0.993735025584029 0.999998854294555 GO:0017171 serine hydrolase activity 6/1271 198/18639 0.0303030303030303 0.4443888133896 0.99389661176613 0.999998854294555 GO:0003774 cytoskeletal motor activity 4/1271 153/18639 0.0261437908496732 0.383394270375341 0.993985186678089 0.999998854294555 GO:0004843 cysteine-type deubiquitinase activity 2/1271 108/18639 0.0185185185185185 0.271570941515867 0.995740190427671 0.999998854294555 GO:0022834 ligand-gated channel activity 5/1271 188/18639 0.0265957446808511 0.390022096857894 0.996721031296823 0.999998854294555 GO:0101005 deubiquitinase activity 2/1271 115/18639 0.0173913043478261 0.255040536380118 0.997259585889106 0.999998854294555 GO:0022832 voltage-gated channel activity 4/1271 175/18639 0.0228571428571429 0.335196133528156 0.99817981011089 0.999998854294555 GO:0019783 ubiquitin-like protein peptidase activity 2/1271 127/18639 0.015748031496063 0.230942217981997 0.998722723690081 0.999998854294555 GO:0015276 ligand-gated monoatomic ion channel activity 4/1271 186/18639 0.021505376344086 0.31537270627649 0.999014843523887 0.999998854294555 GO:0005249 voltage-gated potassium channel activity 1/1271 98/18639 0.0102040816326531 0.149641131039355 0.999031873944689 0.999998854294555 GO:0030527 structural constituent of chromatin 1/1271 98/18639 0.0102040816326531 0.149641131039355 0.999031873944689 0.999998854294555 GO:0015079 potassium ion transmembrane transporter activity 3/1271 160/18639 0.01875 0.274965578284815 0.999033708719439 0.999998854294555 GO:0022843 voltage-gated monoatomic cation channel activity 2/1271 143/18639 0.013986013986014 0.205102529256739 0.999543954150986 0.999998854294555 GO:0005244 voltage-gated monoatomic ion channel activity 3/1271 173/18639 0.0173410404624277 0.254303425003297 0.999557629162143 0.999998854294555 GO:0005267 potassium channel activity 1/1271 124/18639 0.00806451612903226 0.118264764853684 0.999847415684779 0.999998854294555 GO:0005262 calcium channel activity 1/1271 131/18639 0.00763358778625954 0.11194527360196 0.999907258596931 0.999998854294555 GO:0046873 metal ion transmembrane transporter activity 13/1271 450/18639 0.0288888888888889 0.423650668764752 0.999938500741292 0.999998854294555 GO:0005261 monoatomic cation channel activity 8/1271 341/18639 0.0234604105571848 0.344042952301626 0.999952286763109 0.999998854294555 GO:0022836 gated channel activity 7/1271 318/18639 0.0220125786163522 0.322810741801879 0.999955682178033 0.999998854294555 GO:0015085 calcium ion transmembrane transporter activity 1/1271 147/18639 0.00680272108843537 0.0997607540262368 0.999970303794181 0.999998854294555 GO:0005216 monoatomic ion channel activity 11/1271 448/18639 0.0245535714285714 0.360073971563448 0.999992319003656 0.999998854294555 GO:0045182 translation regulator activity 7/1271 356/18639 0.0196629213483146 0.288353415429769 0.999994421394537 0.999998854294555 GO:0030371 translation repressor activity 5/1271 329/18639 0.0151975683890578 0.222869769633082 0.999998854294555 0.999998854294555