ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003725 double-stranded RNA binding 19/600 75/18639 0.253333333333333 7.8698 1.78726004451407e-12 1.63534294073038e-09 GO:0042605 peptide antigen binding 11/600 45/18639 0.244444444444444 7.59366666666667 1.31724509778314e-07 6.02639632235786e-05 GO:0038024 cargo receptor activity 12/600 65/18639 0.184615384615385 5.73507692307692 9.40027187890602e-07 0.000286708292306634 GO:0023026 MHC class II protein complex binding 8/600 27/18639 0.296296296296296 9.20444444444444 1.42161892268116e-06 0.000296031591479999 GO:0042277 peptide binding 24/600 249/18639 0.0963855421686747 2.99421686746988 1.83781971037926e-06 0.000296031591479999 GO:0023023 MHC protein complex binding 9/600 37/18639 0.243243243243243 7.55635135135135 1.94119076380327e-06 0.000296031591479999 GO:0005126 cytokine receptor binding 24/600 275/18639 0.0872727272727273 2.71112727272727 1.02032153239067e-05 0.00133370600305352 GO:0097110 scaffold protein binding 11/600 70/18639 0.157142857142857 4.88164285714286 1.35441971797292e-05 0.00147142188694954 GO:0030228 lipoprotein particle receptor activity 6/600 18/18639 0.333333333333333 10.355 1.44730021667167e-05 0.00147142188694954 GO:0140313 molecular sequestering activity 9/600 55/18639 0.163636363636364 5.08336363636364 5.92171539626453e-05 0.00541836958758204 GO:0140311 protein sequestering activity 7/600 33/18639 0.212121212121212 6.58954545454545 7.12485839565362e-05 0.0059265867563846 GO:0005041 low-density lipoprotein particle receptor activity 5/600 15/18639 0.333333333333333 10.355 7.80633679114881e-05 0.00595233180325097 GO:0045296 cadherin binding 25/600 334/18639 0.0748502994011976 2.3252245508982 8.74006470627383e-05 0.00615166092787735 GO:0031720 haptoglobin binding 4/600 10/18639 0.4 12.426 0.000191233353681115 0.0124984656155872 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 7/600 40/18639 0.175 5.436375 0.000255812401691977 0.0153719500150845 GO:0140297 DNA-binding transcription factor binding 31/600 488/18639 0.0635245901639344 1.97339139344262 0.000268799125946832 0.0153719500150845 GO:0042608 T cell receptor binding 4/600 11/18639 0.363636363636364 11.2963636363636 0.000292869799087825 0.0157632862450212 GO:0048156 tau protein binding 7/600 43/18639 0.162790697674419 5.05709302325581 0.000406765259753929 0.0180032213329886 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 24/600 349/18639 0.0687679083094556 2.13627507163324 0.000423570915439703 0.0180032213329886 GO:0016209 antioxidant activity 10/600 86/18639 0.116279069767442 3.61220930232558 0.000435282318452976 0.0180032213329886 GO:0051015 actin filament binding 17/600 209/18639 0.0813397129186603 2.52681818181818 0.000446358285376486 0.0180032213329886 GO:0004601 peroxidase activity 8/600 57/18639 0.140350877192982 4.36 0.000452539989790971 0.0180032213329886 GO:0016504 peptidase activator activity 8/600 57/18639 0.140350877192982 4.36 0.000452539989790971 0.0180032213329886 GO:0051082 unfolded protein binding 12/600 121/18639 0.0991735537190083 3.08082644628099 0.000532988570366604 0.0203201892452268 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 8/600 59/18639 0.135593220338983 4.21220338983051 0.000574067351423212 0.0210108650620896 GO:0003713 transcription coactivator activity 19/600 256/18639 0.07421875 2.30560546875 0.000661064258293363 0.0232643767822472 GO:0005178 integrin binding 14/600 161/18639 0.0869565217391304 2.70130434782609 0.000723592860625223 0.0245217580545214 GO:0044389 ubiquitin-like protein ligase binding 22/600 322/18639 0.0683229813664596 2.12245341614907 0.000789407782320456 0.025115047839757 GO:0005344 oxygen carrier activity 4/600 14/18639 0.285714285714286 8.87571428571429 0.000822466776192345 0.025115047839757 GO:0031625 ubiquitin protein ligase binding 21/600 302/18639 0.0695364238410596 2.16014900662252 0.000823444191467442 0.025115047839757 GO:0140674 ATP-dependent histone chaperone activity 13/600 152/18639 0.0855263157894737 2.656875 0.00128816825149778 0.0380217403264666 GO:0003712 transcription coregulator activity 29/600 495/18639 0.0585858585858586 1.8199696969697 0.00148616644985934 0.0414316752581813 GO:0019838 growth factor binding 12/600 136/18639 0.0882352941176471 2.74102941176471 0.00149606486155033 0.0414316752581813 GO:0016922 nuclear receptor binding 12/600 137/18639 0.0875912408759124 2.72102189781022 0.00159298488177536 0.0414316752581813 GO:0019887 protein kinase regulator activity 18/600 255/18639 0.0705882352941176 2.19282352941176 0.00159845191663511 0.0414316752581813 GO:0140375 immune receptor activity 13/600 156/18639 0.0833333333333333 2.58875 0.00163009869868254 0.0414316752581813 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 4/600 17/18639 0.235294117647059 7.30941176470588 0.00181091690292918 0.0418013840611659 GO:0030169 low-density lipoprotein particle binding 4/600 17/18639 0.235294117647059 7.30941176470588 0.00181091690292918 0.0418013840611659 GO:0070403 NAD+ binding 4/600 17/18639 0.235294117647059 7.30941176470588 0.00181091690292918 0.0418013840611659 GO:0140658 ATP-dependent chromatin remodeler activity 13/600 158/18639 0.0822784810126582 2.55598101265823 0.00182738290977774 0.0418013840611659 GO:0035198 miRNA binding 6/600 42/18639 0.142857142857143 4.43785714285714 0.00212280523746224 0.0473747998116572 GO:0019207 kinase regulator activity 19/600 287/18639 0.0662020905923345 2.05656794425087 0.0024995738826702 0.0528371706390803 GO:0061980 regulatory RNA binding 7/600 58/18639 0.120689655172414 3.74922413793103 0.00250589126239533 0.0528371706390803 GO:0140713 histone chaperone activity 13/600 164/18639 0.0792682926829268 2.46246951219512 0.00254080383401042 0.0528371706390803 GO:0016411 acylglycerol O-acyltransferase activity 5/600 31/18639 0.161290322580645 5.01048387096774 0.00288594343205831 0.0546653861869191 GO:0070325 lipoprotein particle receptor binding 5/600 31/18639 0.161290322580645 5.01048387096774 0.00288594343205831 0.0546653861869191 GO:0140104 molecular carrier activity 17/600 249/18639 0.0682730923694779 2.12090361445783 0.00300967035084701 0.0546653861869191 GO:0051020 GTPase binding 20/600 315/18639 0.0634920634920635 1.97238095238095 0.00315589591702726 0.0546653861869191 GO:0003724 RNA helicase activity 8/600 77/18639 0.103896103896104 3.22753246753247 0.00329048635674999 0.0546653861869191 GO:0005200 structural constituent of cytoskeleton 10/600 112/18639 0.0892857142857143 2.77366071428571 0.00331166349274932 0.0546653861869191 GO:0071813 lipoprotein particle binding 5/600 32/18639 0.15625 4.85390625 0.00333124004723977 0.0546653861869191 GO:0071814 protein-lipid complex binding 5/600 32/18639 0.15625 4.85390625 0.00333124004723977 0.0546653861869191 GO:0032395 MHC class II receptor activity 3/600 10/18639 0.3 9.3195 0.00336273308815618 0.0546653861869191 GO:0031072 heat shock protein binding 11/600 131/18639 0.083969465648855 2.60851145038168 0.00341356672703187 0.0546653861869191 GO:0016505 peptidase activator activity involved in apoptotic process 4/600 20/18639 0.2 6.213 0.00341482361996712 0.0546653861869191 GO:0042288 MHC class I protein binding 4/600 20/18639 0.2 6.213 0.00341482361996712 0.0546653861869191 GO:0000510 H3-H4 histone complex chaperone activity 12/600 151/18639 0.0794701986754967 2.4687417218543 0.00358461548766683 0.0546653861869191 GO:0140584 chromatin extrusion motor activity 12/600 151/18639 0.0794701986754967 2.4687417218543 0.00358461548766683 0.0546653861869191 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 12/600 151/18639 0.0794701986754967 2.4687417218543 0.00358461548766683 0.0546653861869191 GO:0140849 ATP-dependent H2AZ histone chaperone activity 12/600 151/18639 0.0794701986754967 2.4687417218543 0.00358461548766683 0.0546653861869191 GO:0015616 DNA translocase activity 12/600 152/18639 0.0789473684210526 2.4525 0.00378145382219559 0.056039265868131 GO:0008186 ATP-dependent activity, acting on RNA 8/600 79/18639 0.10126582278481 3.14582278481013 0.00385844125649426 0.056039265868131 GO:0046332 SMAD binding 8/600 79/18639 0.10126582278481 3.14582278481013 0.00385844125649426 0.056039265868131 GO:0061775 cohesin loader activity 12/600 153/18639 0.0784313725490196 2.43647058823529 0.00398689925161141 0.0570002002378818 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 4/600 21/18639 0.19047619047619 5.91714285714286 0.00411227683279238 0.0578882046462312 GO:0003823 antigen binding 13/600 174/18639 0.0747126436781609 2.32094827586207 0.00422608541739042 0.0585889114683672 GO:0019825 oxygen binding 5/600 34/18639 0.147058823529412 4.56838235294118 0.00436653675626618 0.0596325542087098 GO:0005114 type II transforming growth factor beta receptor binding 3/600 11/18639 0.272727272727273 8.47227272727273 0.00451393182155681 0.059858661111949 GO:0034713 type I transforming growth factor beta receptor binding 3/600 11/18639 0.272727272727273 8.47227272727273 0.00451393182155681 0.059858661111949 GO:0120013 lipid transfer activity 7/600 65/18639 0.107692307692308 3.34546153846154 0.00478591968327459 0.0625588072885178 GO:0003779 actin binding 25/600 443/18639 0.0564334085778781 1.75310383747178 0.00493547365987903 0.0636050478702721 GO:0032813 tumor necrosis factor receptor superfamily binding 6/600 50/18639 0.12 3.7278 0.00517979360119715 0.0658265436818805 GO:0003689 DNA clamp loader activity 12/600 160/18639 0.075 2.329875 0.00568888251025583 0.0705494280252185 GO:0042171 lysophosphatidic acid acyltransferase activity 4/600 23/18639 0.173913043478261 5.40260869565217 0.00578274000206709 0.0705494280252185 GO:0071617 lysophospholipid acyltransferase activity 4/600 23/18639 0.173913043478261 5.40260869565217 0.00578274000206709 0.0705494280252185 GO:0035259 nuclear glucocorticoid receptor binding 3/600 12/18639 0.25 7.76625 0.00587585955269879 0.0707422564568341 GO:0043394 proteoglycan binding 5/600 37/18639 0.135135135135135 4.19797297297297 0.00632113833502347 0.0751148256694347 GO:0060229 lipase activator activity 4/600 24/18639 0.166666666666667 5.1775 0.00676547484149279 0.079364224102127 GO:0019955 cytokine binding 11/600 144/18639 0.0763888888888889 2.37302083333333 0.00693908582997696 0.080370424486442 GO:0005172 vascular endothelial growth factor receptor binding 3/600 13/18639 0.230769230769231 7.16884615384615 0.00745779268154336 0.0852985037951521 GO:0120020 cholesterol transfer activity 4/600 25/18639 0.16 4.9704 0.00785264104826069 0.0887057599896115 GO:0140597 protein carrier chaperone 13/600 188/18639 0.0691489361702128 2.14811170212766 0.00799123083628365 0.0891704416487749 GO:0004532 RNA exonuclease activity 5/600 40/18639 0.125 3.883125 0.00881973595319098 0.095165264019942 GO:0035591 signaling adaptor activity 10/600 129/18639 0.0775193798449612 2.40813953488372 0.00888855770743884 0.095165264019942 GO:0005125 cytokine activity 15/600 234/18639 0.0641025641025641 1.99134615384615 0.00901524175476848 0.095165264019942 GO:0008143 poly(A) binding 4/600 26/18639 0.153846153846154 4.77923076923077 0.00904850051337154 0.095165264019942 GO:0050750 low-density lipoprotein particle receptor binding 4/600 26/18639 0.153846153846154 4.77923076923077 0.00904850051337154 0.095165264019942 GO:0005161 platelet-derived growth factor receptor binding 3/600 14/18639 0.214285714285714 6.65678571428571 0.00926742701936635 0.0963601786672751 GO:0042287 MHC protein binding 5/600 41/18639 0.121951219512195 3.78841463414634 0.00978503704188992 0.100598976329542 GO:0005044 scavenger receptor activity 4/600 27/18639 0.148148148148148 4.60222222222222 0.0103570548420559 0.104337959527096 GO:0044183 protein folding chaperone 7/600 75/18639 0.0933333333333333 2.8994 0.0103773639560658 0.104337959527096 GO:0031267 small GTPase binding 17/600 283/18639 0.0600706713780919 1.86609540636042 0.0104908112311398 0.104337959527096 GO:0004953 icosanoid receptor activity 3/600 15/18639 0.2 6.213 0.0113109940430434 0.111285586552524 GO:0045309 protein phosphorylated amino acid binding 6/600 59/18639 0.101694915254237 3.15915254237288 0.0115321301596805 0.112254245703273 GO:0001221 transcription coregulator binding 9/600 115/18639 0.0782608695652174 2.43117391304348 0.012003655587341 0.115614156446495 GO:0005149 interleukin-1 receptor binding 3/600 16/18639 0.1875 5.8246875 0.0135933705507646 0.128226124267522 GO:0055102 lipase inhibitor activity 3/600 16/18639 0.1875 5.8246875 0.0135933705507646 0.128226124267522 GO:0140098 catalytic activity, acting on RNA 21/600 387/18639 0.0542635658914729 1.6856976744186 0.0142559210468238 0.133103752631059 GO:0030295 protein kinase activator activity 10/600 139/18639 0.0719424460431655 2.23489208633094 0.0145241697211411 0.134238538331759 GO:0001965 G-protein alpha-subunit binding 4/600 30/18639 0.133333333333333 4.142 0.0149948492673587 0.136750619678775 GO:0003714 transcription corepressor activity 13/600 204/18639 0.0637254901960784 1.97963235294118 0.0150948771448703 0.136750619678775 GO:0005092 GDP-dissociation inhibitor activity 3/600 17/18639 0.176470588235294 5.48205882352941 0.0161181820467293 0.143185791968518 GO:1990226 histone methyltransferase binding 3/600 17/18639 0.176470588235294 5.48205882352941 0.0161181820467293 0.143185791968518 GO:0004540 RNA nuclease activity 9/600 121/18639 0.0743801652892562 2.31061983471074 0.0163118568985372 0.143512971751553 GO:0001216 DNA-binding transcription activator activity 25/600 491/18639 0.0509164969450102 1.58172097759674 0.0166387450248155 0.144994778073392 GO:0001784 phosphotyrosine residue binding 5/600 47/18639 0.106382978723404 3.30478723404255 0.0171252962001662 0.147826849275019 GO:0001540 amyloid-beta binding 7/600 83/18639 0.0843373493975904 2.61993975903614 0.0174599291295211 0.148986453906761 GO:0019903 protein phosphatase binding 10/600 144/18639 0.0694444444444444 2.15729166666667 0.0181823099903617 0.148986453906761 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 5/600 48/18639 0.104166666666667 3.2359375 0.0186256995065525 0.148986453906761 GO:0038187 pattern recognition receptor activity 5/600 48/18639 0.104166666666667 3.2359375 0.0186256995065525 0.148986453906761 GO:0140693 molecular condensate scaffold activity 5/600 48/18639 0.104166666666667 3.2359375 0.0186256995065525 0.148986453906761 GO:0070717 poly-purine tract binding 4/600 32/18639 0.125 3.883125 0.0187112642709186 0.148986453906761 GO:0120015 sterol transfer activity 4/600 32/18639 0.125 3.883125 0.0187112642709186 0.148986453906761 GO:0008094 ATP-dependent activity, acting on DNA 13/600 210/18639 0.0619047619047619 1.92307142857143 0.0187407381996956 0.148986453906761 GO:0003746 translation elongation factor activity 3/600 18/18639 0.166666666666667 5.1775 0.0188879001674145 0.148986453906761 GO:0098641 cadherin binding involved in cell-cell adhesion 3/600 18/18639 0.166666666666667 5.1775 0.0188879001674145 0.148986453906761 GO:0019209 kinase activator activity 10/600 148/18639 0.0675675675675676 2.09898648648649 0.021564724835211 0.167996852454853 GO:0048020 CCR chemokine receptor binding 5/600 50/18639 0.1 3.1065 0.0218801536557897 0.167996852454853 GO:0034987 immunoglobulin receptor binding 3/600 19/18639 0.157894736842105 4.905 0.0219039344476967 0.167996852454853 GO:1990841 promoter-specific chromatin binding 6/600 68/18639 0.0882352941176471 2.74102941176471 0.0220323740924398 0.167996852454853 GO:0019888 protein phosphatase regulator activity 8/600 107/18639 0.0747663551401869 2.32261682242991 0.0222173892854754 0.16800753054719 GO:0030544 Hsp70 protein binding 5/600 51/18639 0.0980392156862745 3.04558823529412 0.0236373071314447 0.177279803485835 GO:0003727 single-stranded RNA binding 7/600 89/18639 0.0786516853932584 2.44331460674157 0.0246277187557778 0.182180285037105 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 24/600 484/18639 0.0495867768595041 1.5404132231405 0.0246889129449192 0.182180285037105 GO:0016004 phospholipase activator activity 3/600 20/18639 0.15 4.65975 0.0251667187114137 0.183525108908323 GO:0000175 3'-5'-RNA exonuclease activity 4/600 35/18639 0.114285714285714 3.55028571428571 0.0252723100791789 0.183525108908323 GO:0005080 protein kinase C binding 5/600 52/18639 0.0961538461538462 2.98701923076923 0.0254829723591372 0.183597792981185 GO:0030695 GTPase regulator activity 24/600 489/18639 0.049079754601227 1.52466257668712 0.0274288881725542 0.196073692795993 GO:0060589 nucleoside-triphosphatase regulator activity 24/600 490/18639 0.0489795918367347 1.52155102040816 0.0280037891952968 0.198631528013151 GO:0035613 RNA stem-loop binding 3/600 21/18639 0.142857142857143 4.43785714285714 0.0286757923578505 0.200292748148345 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 3/600 21/18639 0.142857142857143 4.43785714285714 0.0286757923578505 0.200292748148345 GO:0051287 NAD binding 5/600 54/18639 0.0925925925925926 2.87638888888889 0.0294448794821918 0.202917237608259 GO:0033218 amide binding 14/600 247/18639 0.0566801619433198 1.76076923076923 0.0294950738818562 0.202917237608259 GO:0043539 protein serine/threonine kinase activator activity 6/600 73/18639 0.0821917808219178 2.55328767123288 0.0300083451171832 0.20490772971808 GO:0051219 phosphoprotein binding 7/600 93/18639 0.0752688172043011 2.33822580645161 0.0303942908450843 0.206005749061127 GO:0008374 O-acyltransferase activity 5/600 55/18639 0.0909090909090909 2.82409090909091 0.0315633708252821 0.208308531642584 GO:0098632 cell-cell adhesion mediator activity 5/600 55/18639 0.0909090909090909 2.82409090909091 0.0315633708252821 0.208308531642584 GO:0061134 peptidase regulator activity 13/600 226/18639 0.0575221238938053 1.78692477876106 0.0316839383518156 0.208308531642584 GO:0002020 protease binding 9/600 136/18639 0.0661764705882353 2.05577205882353 0.0318723436393025 0.208308531642584 GO:0016779 nucleotidyltransferase activity 9/600 136/18639 0.0661764705882353 2.05577205882353 0.0318723436393025 0.208308531642584 GO:0061133 endopeptidase activator activity 3/600 22/18639 0.136363636363636 4.23613636363636 0.0324298768030994 0.208967163907295 GO:0140517 protein-RNA adaptor activity 3/600 22/18639 0.136363636363636 4.23613636363636 0.0324298768030994 0.208967163907295 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 4/600 38/18639 0.105263157894737 3.27 0.0330582449475428 0.210057598104178 GO:0043531 ADP binding 4/600 38/18639 0.105263157894737 3.27 0.0330582449475428 0.210057598104178 GO:0019208 phosphatase regulator activity 8/600 117/18639 0.0683760683760684 2.12410256410256 0.0353493923505074 0.22306685517734 GO:0098631 cell adhesion mediator activity 6/600 76/18639 0.0789473684210526 2.4525 0.0355983770991102 0.223099418121136 GO:0070851 growth factor receptor binding 9/600 139/18639 0.0647482014388489 2.01140287769784 0.0359163507817896 0.223560958947874 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/600 23/18639 0.130434782608696 4.05195652173913 0.0364269473232542 0.223695683226696 GO:0070577 lysine-acetylated histone binding 3/600 23/18639 0.130434782608696 4.05195652173913 0.0364269473232542 0.223695683226696 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/600 10/18639 0.2 6.213 0.039225076239528 0.225729212321812 GO:0004955 prostaglandin receptor activity 2/600 10/18639 0.2 6.213 0.039225076239528 0.225729212321812 GO:0005031 tumor necrosis factor receptor activity 2/600 10/18639 0.2 6.213 0.039225076239528 0.225729212321812 GO:0005381 iron ion transmembrane transporter activity 2/600 10/18639 0.2 6.213 0.039225076239528 0.225729212321812 GO:0008140 cAMP response element binding protein binding 2/600 10/18639 0.2 6.213 0.039225076239528 0.225729212321812 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/600 10/18639 0.2 6.213 0.039225076239528 0.225729212321812 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/600 10/18639 0.2 6.213 0.039225076239528 0.225729212321812 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/600 10/18639 0.2 6.213 0.039225076239528 0.225729212321812 GO:0070513 death domain binding 2/600 10/18639 0.2 6.213 0.039225076239528 0.225729212321812 GO:1905394 retromer complex binding 2/600 10/18639 0.2 6.213 0.039225076239528 0.225729212321812 GO:0005540 hyaluronic acid binding 3/600 24/18639 0.125 3.883125 0.0406643005349345 0.231104565151957 GO:0140033 acetylation-dependent protein binding 3/600 24/18639 0.125 3.883125 0.0406643005349345 0.231104565151957 GO:0001530 lipopolysaccharide binding 4/600 41/18639 0.0975609756097561 3.03073170731707 0.0420955274959862 0.236303114471334 GO:0042169 SH2 domain binding 4/600 41/18639 0.0975609756097561 3.03073170731707 0.0420955274959862 0.236303114471334 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 5/600 60/18639 0.0833333333333333 2.58875 0.0435663251830644 0.243068216722585 GO:0042974 nuclear retinoic acid receptor binding 3/600 25/18639 0.12 3.7278 0.0451386177376627 0.244027712826642 GO:0001618 virus receptor activity 6/600 81/18639 0.0740740740740741 2.30111111111111 0.0463199702378427 0.244027712826642 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 2/600 11/18639 0.181818181818182 5.64818181818182 0.046938663887966 0.244027712826642 GO:0004954 prostanoid receptor activity 2/600 11/18639 0.181818181818182 5.64818181818182 0.046938663887966 0.244027712826642 GO:0010854 adenylate cyclase regulator activity 2/600 11/18639 0.181818181818182 5.64818181818182 0.046938663887966 0.244027712826642 GO:0015173 aromatic amino acid transmembrane transporter activity 2/600 11/18639 0.181818181818182 5.64818181818182 0.046938663887966 0.244027712826642 GO:0019215 intermediate filament binding 2/600 11/18639 0.181818181818182 5.64818181818182 0.046938663887966 0.244027712826642 GO:0032050 clathrin heavy chain binding 2/600 11/18639 0.181818181818182 5.64818181818182 0.046938663887966 0.244027712826642 GO:0032794 GTPase activating protein binding 2/600 11/18639 0.181818181818182 5.64818181818182 0.046938663887966 0.244027712826642 GO:0034511 U3 snoRNA binding 2/600 11/18639 0.181818181818182 5.64818181818182 0.046938663887966 0.244027712826642 GO:0043522 leucine zipper domain binding 2/600 11/18639 0.181818181818182 5.64818181818182 0.046938663887966 0.244027712826642 GO:0048185 activin binding 2/600 11/18639 0.181818181818182 5.64818181818182 0.046938663887966 0.244027712826642 GO:0140272 exogenous protein binding 6/600 82/18639 0.0731707317073171 2.2730487804878 0.0486798983068859 0.250953485677292 GO:0004712 protein serine/threonine/tyrosine kinase activity 4/600 43/18639 0.0930232558139535 2.88976744186047 0.0488193666126317 0.250953485677292 GO:0005160 transforming growth factor beta receptor binding 3/600 26/18639 0.115384615384615 3.58442307692308 0.0498460243321354 0.251843260432432 GO:0008157 protein phosphatase 1 binding 3/600 26/18639 0.115384615384615 3.58442307692308 0.0498460243321354 0.251843260432432 GO:0019865 immunoglobulin binding 3/600 26/18639 0.115384615384615 3.58442307692308 0.0498460243321354 0.251843260432432 GO:0005539 glycosaminoglycan binding 13/600 242/18639 0.0537190082644628 1.66878099173554 0.0501146055717573 0.251843260432432 GO:0016887 ATP hydrolysis activity 20/600 417/18639 0.0479616306954436 1.48992805755396 0.0503686520864863 0.251843260432432 GO:0042826 histone deacetylase binding 8/600 127/18639 0.062992125984252 1.95685039370079 0.0529269275852293 0.260120467272386 GO:0004527 exonuclease activity 6/600 84/18639 0.0714285714285714 2.21892857142857 0.0536184255328665 0.260120467272386 GO:0001671 ATPase activator activity 3/600 27/18639 0.111111111111111 3.45166666666667 0.0547821455183954 0.260120467272386 GO:0035255 ionotropic glutamate receptor binding 3/600 27/18639 0.111111111111111 3.45166666666667 0.0547821455183954 0.260120467272386 GO:0031490 chromatin DNA binding 8/600 128/18639 0.0625 1.9415625 0.0549449433000706 0.260120467272386 GO:0004859 phospholipase inhibitor activity 2/600 12/18639 0.166666666666667 5.1775 0.0551512247550195 0.260120467272386 GO:0004875 complement receptor activity 2/600 12/18639 0.166666666666667 5.1775 0.0551512247550195 0.260120467272386 GO:0005095 GTPase inhibitor activity 2/600 12/18639 0.166666666666667 5.1775 0.0551512247550195 0.260120467272386 GO:0097677 STAT family protein binding 2/600 12/18639 0.166666666666667 5.1775 0.0551512247550195 0.260120467272386 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 2/600 12/18639 0.166666666666667 5.1775 0.0551512247550195 0.260120467272386 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/600 12/18639 0.166666666666667 5.1775 0.0551512247550195 0.260120467272386 GO:0061659 ubiquitin-like protein ligase activity 18/600 372/18639 0.0483870967741935 1.50314516129032 0.0570366507445876 0.267633515032296 GO:0001664 G protein-coupled receptor binding 15/600 297/18639 0.0505050505050505 1.56893939393939 0.0579528150388584 0.270545029390589 GO:0019789 SUMO transferase activity 3/600 28/18639 0.107142857142857 3.32839285714286 0.0599421584683261 0.27561344220361 GO:0051019 mitogen-activated protein kinase binding 3/600 28/18639 0.107142857142857 3.32839285714286 0.0599421584683261 0.27561344220361 GO:0097718 disordered domain specific binding 3/600 28/18639 0.107142857142857 3.32839285714286 0.0599421584683261 0.27561344220361 GO:0043021 ribonucleoprotein complex binding 10/600 177/18639 0.0564971751412429 1.75508474576271 0.0606300961068273 0.277382689688735 GO:0004386 helicase activity 9/600 155/18639 0.0580645161290323 1.80377419354839 0.0634218025189797 0.282115089088157 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/600 13/18639 0.153846153846154 4.77923076923077 0.0638227578592879 0.282115089088157 GO:0005035 death receptor activity 2/600 13/18639 0.153846153846154 4.77923076923077 0.0638227578592879 0.282115089088157 GO:0019855 calcium channel inhibitor activity 2/600 13/18639 0.153846153846154 4.77923076923077 0.0638227578592879 0.282115089088157 GO:0032396 inhibitory MHC class I receptor activity 2/600 13/18639 0.153846153846154 4.77923076923077 0.0638227578592879 0.282115089088157 GO:0035325 Toll-like receptor binding 2/600 13/18639 0.153846153846154 4.77923076923077 0.0638227578592879 0.282115089088157 GO:0043560 insulin receptor substrate binding 2/600 13/18639 0.153846153846154 4.77923076923077 0.0638227578592879 0.282115089088157 GO:0004629 phospholipase C activity 3/600 29/18639 0.103448275862069 3.21362068965517 0.0653208411577228 0.287348892592867 GO:0051087 protein-folding chaperone binding 8/600 134/18639 0.0597014925373134 1.85462686567164 0.0680775470056615 0.297996255525854 GO:0004674 protein serine/threonine kinase activity 20/600 433/18639 0.046189376443418 1.43487297921478 0.0683925832354418 0.297996255525854 GO:0001968 fibronectin binding 3/600 30/18639 0.1 3.1065 0.07091261803443 0.303201147203287 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/600 30/18639 0.1 3.1065 0.07091261803443 0.303201147203287 GO:0048019 receptor antagonist activity 3/600 30/18639 0.1 3.1065 0.07091261803443 0.303201147203287 GO:0070566 adenylyltransferase activity 3/600 30/18639 0.1 3.1065 0.07091261803443 0.303201147203287 GO:0016763 pentosyltransferase activity 4/600 49/18639 0.0816326530612245 2.53591836734694 0.0723006702367188 0.306273672530545 GO:0035254 glutamate receptor binding 4/600 49/18639 0.0816326530612245 2.53591836734694 0.0723006702367188 0.306273672530545 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 2/600 14/18639 0.142857142857143 4.43785714285714 0.0729153129992748 0.307453969559154 GO:0015078 proton transmembrane transporter activity 10/600 185/18639 0.0540540540540541 1.67918918918919 0.0765145515328912 0.320507381104809 GO:0005164 tumor necrosis factor receptor binding 3/600 31/18639 0.0967741935483871 3.00629032258065 0.0767116026906591 0.320507381104809 GO:0140097 catalytic activity, acting on DNA 16/600 336/18639 0.0476190476190476 1.47928571428571 0.0778424158398299 0.323068344412595 GO:0017124 SH3 domain binding 7/600 115/18639 0.0608695652173913 1.89091304347826 0.078030714879982 0.323068344412595 GO:0004857 enzyme inhibitor activity 19/600 416/18639 0.0456730769230769 1.41883413461538 0.0807524198117009 0.327780452112467 GO:0008234 cysteine-type peptidase activity 10/600 187/18639 0.053475935828877 1.66122994652406 0.0808547629767499 0.327780452112467 GO:0016755 aminoacyltransferase activity 22/600 496/18639 0.0443548387096774 1.37788306451613 0.0815171441029414 0.327780452112467 GO:0042379 chemokine receptor binding 5/600 72/18639 0.0694444444444444 2.15729166666667 0.0821713907945738 0.327780452112467 GO:0031386 protein tag activity 2/600 15/18639 0.133333333333333 4.142 0.0823929005310027 0.327780452112467 GO:0042809 nuclear vitamin D receptor binding 2/600 15/18639 0.133333333333333 4.142 0.0823929005310027 0.327780452112467 GO:0141047 molecular tag activity 2/600 15/18639 0.133333333333333 4.142 0.0823929005310027 0.327780452112467 GO:0141050 histone H3K deacetylase activity 2/600 15/18639 0.133333333333333 4.142 0.0823929005310027 0.327780452112467 GO:0141051 histone H4K deacetylase activity 2/600 15/18639 0.133333333333333 4.142 0.0823929005310027 0.327780452112467 GO:1990782 protein tyrosine kinase binding 7/600 117/18639 0.0598290598290598 1.85858974358974 0.0837650616816518 0.331796672894854 GO:0030159 signaling receptor complex adaptor activity 4/600 52/18639 0.0769230769230769 2.38961538461538 0.0858428317126584 0.338561168177079 GO:0019902 phosphatase binding 10/600 190/18639 0.0526315789473684 1.635 0.0876436568503101 0.344180025828471 GO:0015399 primary active transmembrane transporter activity 9/600 166/18639 0.0542168674698795 1.68424698795181 0.0884826371969718 0.345989799295851 GO:0071889 14-3-3 protein binding 3/600 33/18639 0.0909090909090909 2.82409090909091 0.088906331768768 0.346167206674139 GO:0048029 monosaccharide binding 5/600 74/18639 0.0675675675675676 2.09898648648649 0.0899347299696957 0.34868761831471 GO:0140296 general transcription initiation factor binding 4/600 53/18639 0.0754716981132075 2.34452830188679 0.0906121700789697 0.349831795874503 GO:0022858 alanine transmembrane transporter activity 2/600 16/18639 0.125 3.883125 0.0922214048138939 0.35159410585297 GO:0030275 LRR domain binding 2/600 16/18639 0.125 3.883125 0.0922214048138939 0.35159410585297 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/600 16/18639 0.125 3.883125 0.0922214048138939 0.35159410585297 GO:0030332 cyclin binding 3/600 34/18639 0.0882352941176471 2.74102941176471 0.0952890943552831 0.359619676106754 GO:0019787 ubiquitin-like protein transferase activity 21/600 479/18639 0.0438413361169102 1.36193110647182 0.0953326604764271 0.359619676106754 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/600 54/18639 0.0740740740740741 2.30111111111111 0.0955055533267118 0.359619676106754 GO:0005096 GTPase activator activity 13/600 271/18639 0.0479704797047971 1.49020295202952 0.099928359542239 0.374731348283396 GO:0005154 epidermal growth factor receptor binding 3/600 35/18639 0.0857142857142857 2.66271428571429 0.101853167881168 0.376173407961072 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/600 17/18639 0.117647058823529 3.65470588235294 0.102368501182849 0.376173407961072 GO:0008429 phosphatidylethanolamine binding 2/600 17/18639 0.117647058823529 3.65470588235294 0.102368501182849 0.376173407961072 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/600 17/18639 0.117647058823529 3.65470588235294 0.102368501182849 0.376173407961072 GO:0046965 nuclear retinoid X receptor binding 2/600 17/18639 0.117647058823529 3.65470588235294 0.102368501182849 0.376173407961072 GO:0008201 heparin binding 9/600 172/18639 0.0523255813953488 1.62549418604651 0.104311872541185 0.381781453500738 GO:0061630 ubiquitin protein ligase activity 16/600 353/18639 0.0453257790368272 1.40804532577904 0.10756588742092 0.389652418734963 GO:0005484 SNAP receptor activity 3/600 36/18639 0.0833333333333333 2.58875 0.108591657680236 0.389652418734963 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 3/600 36/18639 0.0833333333333333 2.58875 0.108591657680236 0.389652418734963 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 3/600 36/18639 0.0833333333333333 2.58875 0.108591657680236 0.389652418734963 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 3/600 36/18639 0.0833333333333333 2.58875 0.108591657680236 0.389652418734963 GO:0033293 monocarboxylic acid binding 5/600 79/18639 0.0632911392405063 1.96613924050633 0.110922985059316 0.39395142108186 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/600 18/18639 0.111111111111111 3.45166666666667 0.112803576309778 0.39395142108186 GO:0004706 JUN kinase kinase kinase activity 2/600 18/18639 0.111111111111111 3.45166666666667 0.112803576309778 0.39395142108186 GO:0008525 phosphatidylcholine transporter activity 2/600 18/18639 0.111111111111111 3.45166666666667 0.112803576309778 0.39395142108186 GO:0032393 MHC class I receptor activity 2/600 18/18639 0.111111111111111 3.45166666666667 0.112803576309778 0.39395142108186 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/600 18/18639 0.111111111111111 3.45166666666667 0.112803576309778 0.39395142108186 GO:1901611 phosphatidylglycerol binding 2/600 18/18639 0.111111111111111 3.45166666666667 0.112803576309778 0.39395142108186 GO:0019213 deacetylase activity 3/600 37/18639 0.0810810810810811 2.51878378378378 0.11549755980164 0.40182611109696 GO:0008408 3'-5' exonuclease activity 4/600 58/18639 0.0689655172413793 2.14241379310345 0.116270697341263 0.402983666921423 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 7/600 128/18639 0.0546875 1.6988671875 0.119452147459659 0.412447980851276 GO:0001786 phosphatidylserine binding 4/600 59/18639 0.0677966101694915 2.10610169491525 0.121746720247894 0.415442468448576 GO:0015459 potassium channel regulator activity 4/600 59/18639 0.0677966101694915 2.10610169491525 0.121746720247894 0.415442468448576 GO:0042162 telomeric DNA binding 3/600 38/18639 0.0789473684210526 2.4525 0.122563786789134 0.415442468448576 GO:0008301 DNA binding, bending 2/600 19/18639 0.105263157894737 3.27 0.123497651822965 0.415442468448576 GO:0043395 heparan sulfate proteoglycan binding 2/600 19/18639 0.105263157894737 3.27 0.123497651822965 0.415442468448576 GO:0097001 ceramide binding 2/600 19/18639 0.105263157894737 3.27 0.123497651822965 0.415442468448576 GO:0140036 ubiquitin-modified protein reader activity 2/600 19/18639 0.105263157894737 3.27 0.123497651822965 0.415442468448576 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 7/600 130/18639 0.0538461538461538 1.67273076923077 0.126671863827046 0.424559543596144 GO:0008135 translation factor activity, RNA binding 5/600 83/18639 0.0602409638554217 1.87138554216867 0.129259965194148 0.430259493723072 GO:0000217 DNA secondary structure binding 3/600 39/18639 0.0769230769230769 2.38961538461538 0.129783191549254 0.430259493723072 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 3/600 39/18639 0.0769230769230769 2.38961538461538 0.129783191549254 0.430259493723072 GO:0004860 protein kinase inhibitor activity 5/600 84/18639 0.0595238095238095 1.84910714285714 0.134047404413217 0.436160743325131 GO:0180051 translation factor activity 5/600 84/18639 0.0595238095238095 1.84910714285714 0.134047404413217 0.436160743325131 GO:0000339 RNA cap binding 2/600 20/18639 0.1 3.1065 0.134423311057581 0.436160743325131 GO:0001972 retinoic acid binding 2/600 20/18639 0.1 3.1065 0.134423311057581 0.436160743325131 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/600 20/18639 0.1 3.1065 0.134423311057581 0.436160743325131 GO:0010851 cyclase regulator activity 2/600 20/18639 0.1 3.1065 0.134423311057581 0.436160743325131 GO:0004842 ubiquitin-protein transferase activity 19/600 449/18639 0.0423162583518931 1.31455456570156 0.137750918723051 0.445378412125765 GO:0004518 nuclease activity 10/600 209/18639 0.0478468899521531 1.48636363636364 0.138316636825267 0.445632826391265 GO:0004222 metalloendopeptidase activity 6/600 110/18639 0.0545454545454545 1.69445454545455 0.144013063824482 0.459249949538395 GO:0008137 NADH dehydrogenase (ubiquinone) activity 3/600 41/18639 0.0731707317073171 2.2730487804878 0.144652778515054 0.459249949538395 GO:0015175 neutral L-amino acid transmembrane transporter activity 3/600 41/18639 0.0731707317073171 2.2730487804878 0.144652778515054 0.459249949538395 GO:0005123 death receptor binding 2/600 21/18639 0.0952380952380952 2.95857142857143 0.145554628815448 0.459249949538395 GO:0070182 DNA polymerase binding 2/600 21/18639 0.0952380952380952 2.95857142857143 0.145554628815448 0.459249949538395 GO:0072542 protein phosphatase activator activity 2/600 21/18639 0.0952380952380952 2.95857142857143 0.145554628815448 0.459249949538395 GO:0044325 transmembrane transporter binding 7/600 136/18639 0.0514705882352941 1.59893382352941 0.149602774005309 0.468377274140597 GO:0031406 carboxylic acid binding 9/600 187/18639 0.0481283422459893 1.49510695187166 0.150348036678413 0.468377274140597 GO:0016859 cis-trans isomerase activity 3/600 42/18639 0.0714285714285714 2.21892857142857 0.152288558522806 0.468377274140597 GO:0042056 chemoattractant activity 3/600 42/18639 0.0714285714285714 2.21892857142857 0.152288558522806 0.468377274140597 GO:0051879 Hsp90 protein binding 3/600 42/18639 0.0714285714285714 2.21892857142857 0.152288558522806 0.468377274140597 GO:0008083 growth factor activity 8/600 162/18639 0.0493827160493827 1.53407407407407 0.152526723135351 0.468377274140597 GO:0004197 cysteine-type endopeptidase activity 5/600 88/18639 0.0568181818181818 1.76505681818182 0.153962319036084 0.468377274140597 GO:0004407 histone deacetylase activity 2/600 22/18639 0.0909090909090909 2.82409090909091 0.156867104016683 0.468377274140597 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/600 22/18639 0.0909090909090909 2.82409090909091 0.156867104016683 0.468377274140597 GO:0031683 G-protein beta/gamma-subunit complex binding 2/600 22/18639 0.0909090909090909 2.82409090909091 0.156867104016683 0.468377274140597 GO:0033558 protein lysine deacetylase activity 2/600 22/18639 0.0909090909090909 2.82409090909091 0.156867104016683 0.468377274140597 GO:0034062 5'-3' RNA polymerase activity 2/600 22/18639 0.0909090909090909 2.82409090909091 0.156867104016683 0.468377274140597 GO:0050321 tau-protein kinase activity 2/600 22/18639 0.0909090909090909 2.82409090909091 0.156867104016683 0.468377274140597 GO:0070034 telomerase RNA binding 2/600 22/18639 0.0909090909090909 2.82409090909091 0.156867104016683 0.468377274140597 GO:0097747 RNA polymerase activity 2/600 22/18639 0.0909090909090909 2.82409090909091 0.156867104016683 0.468377274140597 GO:0140035 ubiquitin-like protein reader activity 2/600 22/18639 0.0909090909090909 2.82409090909091 0.156867104016683 0.468377274140597 GO:0043177 organic acid binding 9/600 189/18639 0.0476190476190476 1.47928571428571 0.157149533509468 0.468377274140597 GO:0008200 ion channel inhibitor activity 3/600 43/18639 0.0697674418604651 2.16732558139535 0.160048747916069 0.475469494620789 GO:0019210 kinase inhibitor activity 5/600 90/18639 0.0555555555555556 1.72583333333333 0.164354836078581 0.479840808549106 GO:0004713 protein tyrosine kinase activity 7/600 140/18639 0.05 1.55325 0.165896313430024 0.479840808549106 GO:0035401 histone H3Y41 kinase activity 6/600 115/18639 0.0521739130434783 1.62078260869565 0.166524379261723 0.479840808549106 GO:0140801 histone H2AXY142 kinase activity 6/600 115/18639 0.0521739130434783 1.62078260869565 0.166524379261723 0.479840808549106 GO:0001046 core promoter sequence-specific DNA binding 3/600 44/18639 0.0681818181818182 2.11806818181818 0.167926199796937 0.479840808549106 GO:0003954 NADH dehydrogenase activity 3/600 44/18639 0.0681818181818182 2.11806818181818 0.167926199796937 0.479840808549106 GO:0016248 channel inhibitor activity 3/600 44/18639 0.0681818181818182 2.11806818181818 0.167926199796937 0.479840808549106 GO:0030547 signaling receptor inhibitor activity 3/600 44/18639 0.0681818181818182 2.11806818181818 0.167926199796937 0.479840808549106 GO:0000295 adenine nucleotide transmembrane transporter activity 2/600 23/18639 0.0869565217391304 2.70130434782609 0.168337595130342 0.479840808549106 GO:0005158 insulin receptor binding 2/600 23/18639 0.0869565217391304 2.70130434782609 0.168337595130342 0.479840808549106 GO:0017134 fibroblast growth factor binding 2/600 23/18639 0.0869565217391304 2.70130434782609 0.168337595130342 0.479840808549106 GO:0043274 phospholipase binding 2/600 23/18639 0.0869565217391304 2.70130434782609 0.168337595130342 0.479840808549106 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/600 23/18639 0.0869565217391304 2.70130434782609 0.168337595130342 0.479840808549106 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/600 67/18639 0.0597014925373134 1.85462686567164 0.169197528554729 0.480597573755626 GO:0072341 modified amino acid binding 5/600 91/18639 0.0549450549450549 1.70686813186813 0.169653569751986 0.480597573755626 GO:0141003 histone H2AX kinase activity 15/600 354/18639 0.0423728813559322 1.31631355932203 0.170755773521668 0.481429813806936 GO:0009055 electron transfer activity 6/600 116/18639 0.0517241379310345 1.60681034482759 0.171196523710294 0.481429813806936 GO:0020037 heme binding 7/600 142/18639 0.0492957746478873 1.53137323943662 0.174326929700746 0.481429813806936 GO:0035402 histone H3T11 kinase activity 11/600 247/18639 0.0445344129554656 1.38346153846154 0.174605808860468 0.481429813806936 GO:0052689 carboxylic ester hydrolase activity 5/600 92/18639 0.0543478260869565 1.6883152173913 0.17501813058893 0.481429813806936 GO:0005548 phospholipid transporter activity 4/600 68/18639 0.0588235294117647 1.82735294117647 0.175536865521725 0.481429813806936 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 4/600 68/18639 0.0588235294117647 1.82735294117647 0.175536865521725 0.481429813806936 GO:0030145 manganese ion binding 4/600 68/18639 0.0588235294117647 1.82735294117647 0.175536865521725 0.481429813806936 GO:0008009 chemokine activity 3/600 45/18639 0.0666666666666667 2.071 0.175913816378304 0.481429813806936 GO:0046915 transition metal ion transmembrane transporter activity 3/600 45/18639 0.0666666666666667 2.071 0.175913816378304 0.481429813806936 GO:0141110 transporter inhibitor activity 3/600 45/18639 0.0666666666666667 2.071 0.175913816378304 0.481429813806936 GO:0140996 histone H3 kinase activity 15/600 357/18639 0.0420168067226891 1.30525210084034 0.178663847141808 0.481429813806936 GO:0035035 histone acetyltransferase binding 2/600 24/18639 0.0833333333333333 2.58875 0.179944258275379 0.481429813806936 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/600 24/18639 0.0833333333333333 2.58875 0.179944258275379 0.481429813806936 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/600 24/18639 0.0833333333333333 2.58875 0.179944258275379 0.481429813806936 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/600 24/18639 0.0833333333333333 2.58875 0.179944258275379 0.481429813806936 GO:0048027 mRNA 5'-UTR binding 2/600 24/18639 0.0833333333333333 2.58875 0.179944258275379 0.481429813806936 GO:0050431 transforming growth factor beta binding 2/600 24/18639 0.0833333333333333 2.58875 0.179944258275379 0.481429813806936 GO:0070300 phosphatidic acid binding 2/600 24/18639 0.0833333333333333 2.58875 0.179944258275379 0.481429813806936 GO:0022853 active monoatomic ion transmembrane transporter activity 6/600 118/18639 0.0508474576271186 1.57957627118644 0.180701227207054 0.482045547797243 GO:0003924 GTPase activity 14/600 331/18639 0.0422960725075529 1.31392749244713 0.182624204935636 0.485759149756126 GO:0030291 protein serine/threonine kinase inhibitor activity 3/600 46/18639 0.0652173913043478 2.02597826086956 0.184004562208629 0.488012099770711 GO:0035173 histone kinase activity 15/600 360/18639 0.0416666666666667 1.294375 0.186751465386595 0.493865869447208 GO:0106310 protein serine kinase activity 15/600 361/18639 0.0415512465373961 1.29078947368421 0.189486469890603 0.498173373182273 GO:0004709 MAP kinase kinase kinase activity 2/600 25/18639 0.08 2.4852 0.191666487887355 0.498173373182273 GO:0005537 D-mannose binding 2/600 25/18639 0.08 2.4852 0.191666487887355 0.498173373182273 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/600 25/18639 0.08 2.4852 0.191666487887355 0.498173373182273 GO:0019211 phosphatase activator activity 2/600 25/18639 0.08 2.4852 0.191666487887355 0.498173373182273 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/600 25/18639 0.08 2.4852 0.191666487887355 0.498173373182273 GO:0140359 ABC-type transporter activity 3/600 47/18639 0.0638297872340425 1.98287234042553 0.192191476211303 0.498173373182273 GO:0140030 modification-dependent protein binding 8/600 173/18639 0.046242774566474 1.43653179190751 0.195267757678361 0.504717509253391 GO:0004896 cytokine receptor activity 5/600 96/18639 0.0520833333333333 1.61796875 0.197096162506645 0.507435332470618 GO:0004435 phosphatidylinositol phospholipase C activity 2/600 26/18639 0.0769230769230769 2.38961538461538 0.20348485985029 0.507435332470618 GO:0004529 DNA exonuclease activity 2/600 26/18639 0.0769230769230769 2.38961538461538 0.20348485985029 0.507435332470618 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 2/600 26/18639 0.0769230769230769 2.38961538461538 0.20348485985029 0.507435332470618 GO:0015216 purine nucleotide transmembrane transporter activity 2/600 26/18639 0.0769230769230769 2.38961538461538 0.20348485985029 0.507435332470618 GO:0030247 polysaccharide binding 2/600 26/18639 0.0769230769230769 2.38961538461538 0.20348485985029 0.507435332470618 GO:0034237 protein kinase A regulatory subunit binding 2/600 26/18639 0.0769230769230769 2.38961538461538 0.20348485985029 0.507435332470618 GO:0043548 phosphatidylinositol 3-kinase binding 2/600 26/18639 0.0769230769230769 2.38961538461538 0.20348485985029 0.507435332470618 GO:0051139 metal cation:proton antiporter activity 2/600 26/18639 0.0769230769230769 2.38961538461538 0.20348485985029 0.507435332470618 GO:0070006 metalloaminopeptidase activity 2/600 26/18639 0.0769230769230769 2.38961538461538 0.20348485985029 0.507435332470618 GO:0070412 R-SMAD binding 2/600 26/18639 0.0769230769230769 2.38961538461538 0.20348485985029 0.507435332470618 GO:0120014 phospholipid transfer activity 2/600 26/18639 0.0769230769230769 2.38961538461538 0.20348485985029 0.507435332470618 GO:0003735 structural constituent of ribosome 8/600 175/18639 0.0457142857142857 1.42011428571429 0.203528707122095 0.507435332470618 GO:0004521 RNA endonuclease activity 4/600 73/18639 0.0547945205479452 1.70219178082192 0.208362490636854 0.516422045242249 GO:0042626 ATPase-coupled transmembrane transporter activity 5/600 98/18639 0.0510204081632653 1.58494897959184 0.208479463968885 0.516422045242249 GO:0060590 ATPase regulator activity 3/600 49/18639 0.0612244897959184 1.9019387755102 0.208826400808341 0.516422045242249 GO:0008320 protein transmembrane transporter activity 2/600 27/18639 0.0740740740740741 2.30111111111111 0.215381076996841 0.528347682177238 GO:0015252 proton channel activity 2/600 27/18639 0.0740740740740741 2.30111111111111 0.215381076996841 0.528347682177238 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/600 27/18639 0.0740740740740741 2.30111111111111 0.215381076996841 0.528347682177238 GO:0005319 lipid transporter activity 8/600 178/18639 0.0449438202247191 1.3961797752809 0.216175526489953 0.528878627642531 GO:0046906 tetrapyrrole binding 7/600 152/18639 0.0460526315789474 1.430625 0.21904326636396 0.534465569928061 GO:0005010 insulin-like growth factor receptor activity 3/600 51/18639 0.0588235294117647 1.82735294117647 0.225764778578938 0.548850115959208 GO:0046625 sphingolipid binding 2/600 28/18639 0.0714285714285714 2.21892857142857 0.22733791688365 0.548850115959208 GO:0046875 ephrin receptor binding 2/600 28/18639 0.0714285714285714 2.21892857142857 0.22733791688365 0.548850115959208 GO:0051959 dynein light intermediate chain binding 2/600 28/18639 0.0714285714285714 2.21892857142857 0.22733791688365 0.548850115959208 GO:0004175 endopeptidase activity 16/600 405/18639 0.0395061728395062 1.22725925925926 0.234828951044387 0.560074188515069 GO:0051861 glycolipid binding 2/600 29/18639 0.0689655172413793 2.14241379310345 0.239339181752237 0.560074188515069 GO:0008237 metallopeptidase activity 8/600 184/18639 0.0434782608695652 1.35065217391304 0.242315200636411 0.560074188515069 GO:0061135 endopeptidase regulator activity 8/600 184/18639 0.0434782608695652 1.35065217391304 0.242315200636411 0.560074188515069 GO:0038064 collagen receptor activity 3/600 53/18639 0.0566037735849057 1.75839622641509 0.242954583885564 0.560074188515069 GO:0015215 nucleotide transmembrane transporter activity 2/600 30/18639 0.0666666666666667 2.071 0.251369650589224 0.560074188515069 GO:0031210 phosphatidylcholine binding 2/600 30/18639 0.0666666666666667 2.071 0.251369650589224 0.560074188515069 GO:0031624 ubiquitin conjugating enzyme binding 2/600 30/18639 0.0666666666666667 2.071 0.251369650589224 0.560074188515069 GO:0017069 snRNA binding 3/600 54/18639 0.0555555555555556 1.72583333333333 0.251628056271379 0.560074188515069 GO:0005179 hormone activity 6/600 132/18639 0.0454545454545455 1.41204545454545 0.25239940397264 0.560074188515069 GO:0000149 SNARE binding 5/600 106/18639 0.0471698113207547 1.46533018867925 0.255929390527995 0.560074188515069 GO:0048306 calcium-dependent protein binding 4/600 80/18639 0.05 1.55325 0.256866004878166 0.560074188515069 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 10/600 243/18639 0.0411522633744856 1.2783950617284 0.258249263463902 0.560074188515069 GO:0030971 receptor tyrosine kinase binding 4/600 81/18639 0.0493827160493827 1.53407407407407 0.263979775084927 0.560074188515069 GO:0033192 calmodulin-dependent protein phosphatase activity 4/600 81/18639 0.0493827160493827 1.53407407407407 0.263979775084927 0.560074188515069 GO:0140791 histone H2AXS140 phosphatase activity 4/600 81/18639 0.0493827160493827 1.53407407407407 0.263979775084927 0.560074188515069 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 4/600 81/18639 0.0493827160493827 1.53407407407407 0.263979775084927 0.560074188515069 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 4/600 81/18639 0.0493827160493827 1.53407407407407 0.263979775084927 0.560074188515069 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 4/600 81/18639 0.0493827160493827 1.53407407407407 0.263979775084927 0.560074188515069 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 4/600 81/18639 0.0493827160493827 1.53407407407407 0.263979775084927 0.560074188515069 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 4/600 81/18639 0.0493827160493827 1.53407407407407 0.263979775084927 0.560074188515069 GO:1990439 MAP kinase serine/threonine phosphatase activity 4/600 81/18639 0.0493827160493827 1.53407407407407 0.263979775084927 0.560074188515069 GO:0004676 3-phosphoinositide-dependent protein kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0004711 ribosomal protein S6 kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0035175 histone H3S10 kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0035979 histone H2AXS139 kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0044022 histone H3S28 kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0044023 histone H4S1 kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0044024 histone H2AS1 kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0044025 histone H2BS14 kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0072354 histone H3T3 kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0072371 histone H2AS121 kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0072518 Rho-dependent protein serine/threonine kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0140823 histone H2BS36 kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0140855 histone H3S57 kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0140995 histone H2A kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0140997 histone H4 kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0140998 histone H2B kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:1990244 histone H2AT120 kinase activity 10/600 245/18639 0.0408163265306122 1.26795918367347 0.266223533768111 0.560074188515069 GO:0004843 cysteine-type deubiquitinase activity 5/600 108/18639 0.0462962962962963 1.43819444444444 0.268188754982797 0.560074188515069 GO:0004677 DNA-dependent protein kinase activity 10/600 246/18639 0.040650406504065 1.26280487804878 0.270239935715639 0.560074188515069 GO:0140857 histone H3T45 kinase activity 10/600 246/18639 0.040650406504065 1.26280487804878 0.270239935715639 0.560074188515069 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 4/600 82/18639 0.0487804878048781 1.51536585365854 0.271129902320649 0.560074188515069 GO:0033549 MAP kinase phosphatase activity 4/600 82/18639 0.0487804878048781 1.51536585365854 0.271129902320649 0.560074188515069 GO:1901681 sulfur compound binding 11/600 275/18639 0.04 1.2426 0.273406506849537 0.560074188515069 GO:0035403 histone H3T6 kinase activity 10/600 247/18639 0.0404858299595142 1.25769230769231 0.274275130941596 0.560074188515069 GO:0042393 histone binding 10/600 247/18639 0.0404858299595142 1.25769230769231 0.274275130941596 0.560074188515069 GO:0004620 phospholipase activity 5/600 109/18639 0.0458715596330275 1.425 0.2743666500653 0.560074188515069 GO:0022884 macromolecule transmembrane transporter activity 2/600 32/18639 0.0625 1.9415625 0.275461926236472 0.560074188515069 GO:0030515 snoRNA binding 2/600 32/18639 0.0625 1.9415625 0.275461926236472 0.560074188515069 GO:0043425 bHLH transcription factor binding 2/600 32/18639 0.0625 1.9415625 0.275461926236472 0.560074188515069 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 4/600 83/18639 0.0481927710843374 1.49710843373494 0.278313190276421 0.560074188515069 GO:0004679 AMP-activated protein kinase activity 10/600 248/18639 0.0403225806451613 1.25262096774194 0.278328576885595 0.560074188515069 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0005131 growth hormone receptor binding 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0005522 profilin binding 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0005528 FK506 binding 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0008190 eukaryotic initiation factor 4E binding 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0015279 store-operated calcium channel activity 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0016427 tRNA (cytidine) methyltransferase activity 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0030957 Tat protein binding 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0031434 mitogen-activated protein kinase kinase binding 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0035256 G protein-coupled glutamate receptor binding 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0042975 peroxisome proliferator activated receptor binding 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0043208 glycosphingolipid binding 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0043422 protein kinase B binding 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0050815 phosphoserine residue binding 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0098505 G-rich strand telomeric DNA binding 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0099122 RNA polymerase II C-terminal domain binding 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0141109 transporter activator activity 1/600 10/18639 0.1 3.1065 0.279118939850133 0.560074188515069 GO:0017018 myosin phosphatase activity 4/600 84/18639 0.0476190476190476 1.47928571428571 0.285526479569582 0.562273018726441 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 3/600 58/18639 0.0517241379310345 1.60681034482759 0.286706177455347 0.562273018726441 GO:0019239 deaminase activity 2/600 33/18639 0.0606060606060606 1.88272727272727 0.28749777104084 0.562273018726441 GO:0030296 protein tyrosine kinase activator activity 2/600 33/18639 0.0606060606060606 1.88272727272727 0.28749777104084 0.562273018726441 GO:0140416 transcription regulator inhibitor activity 2/600 33/18639 0.0606060606060606 1.88272727272727 0.28749777104084 0.562273018726441 GO:0030246 carbohydrate binding 11/600 280/18639 0.0392857142857143 1.22041071428571 0.292720716009254 0.562273018726441 GO:0043022 ribosome binding 5/600 112/18639 0.0446428571428571 1.38683035714286 0.293068737193351 0.562273018726441 GO:0004879 nuclear receptor activity 3/600 59/18639 0.0508474576271186 1.57957627118644 0.295543291234318 0.562273018726441 GO:0070063 RNA polymerase binding 3/600 59/18639 0.0508474576271186 1.57957627118644 0.295543291234318 0.562273018726441 GO:0016247 channel regulator activity 7/600 168/18639 0.0416666666666667 1.294375 0.297592851692633 0.562273018726441 GO:0015035 protein-disulfide reductase activity 2/600 34/18639 0.0588235294117647 1.82735294117647 0.299510813333687 0.562273018726441 GO:0052866 phosphatidylinositol phosphate phosphatase activity 2/600 34/18639 0.0588235294117647 1.82735294117647 0.299510813333687 0.562273018726441 GO:0000099 sulfur amino acid transmembrane transporter activity 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0001851 complement component C3b binding 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0002162 dystroglycan binding 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0003953 NAD+ nucleosidase activity 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0005536 D-glucose binding 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0008432 JUN kinase binding 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0008526 phosphatidylinositol transfer activity 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0015217 ADP transmembrane transporter activity 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0019107 myristoyltransferase activity 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0019864 IgG binding 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0031731 CCR6 chemokine receptor binding 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0048407 platelet-derived growth factor binding 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0050998 nitric-oxide synthase binding 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0070697 activin receptor binding 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0070990 snRNP binding 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0140031 phosphorylation-dependent protein binding 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0180030 inositol phosphate kinase activity 1/600 11/18639 0.0909090909090909 2.82409090909091 0.302336967446349 0.562273018726441 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/600 60/18639 0.05 1.55325 0.30439656792133 0.562878190755866 GO:0098531 ligand-modulated transcription factor activity 3/600 60/18639 0.05 1.55325 0.30439656792133 0.562878190755866 GO:0008081 phosphoric diester hydrolase activity 4/600 87/18639 0.0459770114942529 1.42827586206897 0.307315368601132 0.562878190755866 GO:0141108 transporter regulator activity 7/600 170/18639 0.0411764705882353 1.27914705882353 0.307844100526986 0.562878190755866 GO:0043015 gamma-tubulin binding 2/600 35/18639 0.0571428571428571 1.77514285714286 0.311490064573234 0.562878190755866 GO:0101005 deubiquitinase activity 5/600 115/18639 0.0434782608695652 1.35065217391304 0.311981192312718 0.562878190755866 GO:0019905 syntaxin binding 3/600 61/18639 0.0491803278688525 1.5277868852459 0.313260837446202 0.562878190755866 GO:0016651 oxidoreductase activity, acting on NAD(P)H 4/600 88/18639 0.0454545454545455 1.41204545454545 0.314617894770897 0.562878190755866 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 4/600 89/18639 0.0449438202247191 1.3961797752809 0.321935263708848 0.562878190755866 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 4/600 89/18639 0.0449438202247191 1.3961797752809 0.321935263708848 0.562878190755866 GO:0015179 L-amino acid transmembrane transporter activity 3/600 62/18639 0.0483870967741935 1.50314516129032 0.32213108332654 0.562878190755866 GO:0005085 guanyl-nucleotide exchange factor activity 9/600 230/18639 0.0391304347826087 1.21558695652174 0.322974426112492 0.562878190755866 GO:0000993 RNA polymerase II complex binding 2/600 36/18639 0.0555555555555556 1.72583333333333 0.323425264978705 0.562878190755866 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/600 36/18639 0.0555555555555556 1.72583333333333 0.323425264978705 0.562878190755866 GO:0000340 RNA 7-methylguanosine cap binding 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0003995 acyl-CoA dehydrogenase activity 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0004000 adenosine deaminase activity 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0005078 MAP-kinase scaffold activity 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0005165 neurotrophin receptor binding 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0005527 macrolide binding 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0008179 adenylate cyclase binding 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0010853 cyclase activator activity 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0016840 carbon-nitrogen lyase activity 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0017166 vinculin binding 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0031543 peptidyl-proline dioxygenase activity 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0035497 cAMP response element binding 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0043047 single-stranded telomeric DNA binding 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/600 12/18639 0.0833333333333333 2.58875 0.324808398600106 0.562878190755866 GO:0140793 histone H2AXY142 phosphatase activity 4/600 90/18639 0.0444444444444444 1.38066666666667 0.329264585924209 0.569521920832989 GO:0022829 wide pore channel activity 2/600 37/18639 0.0540540540540541 1.67918918918919 0.335306848131679 0.577788636611085 GO:0030280 structural constituent of skin epidermis 2/600 37/18639 0.0540540540540541 1.67918918918919 0.335306848131679 0.577788636611085 GO:0005543 phospholipid binding 18/600 497/18639 0.0362173038229376 1.12509054325956 0.337648665062822 0.58073031679038 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/600 13/18639 0.0769230769230769 2.38961538461538 0.346557201995175 0.583860670941298 GO:0004465 lipoprotein lipase activity 1/600 13/18639 0.0769230769230769 2.38961538461538 0.346557201995175 0.583860670941298 GO:0005542 folic acid binding 1/600 13/18639 0.0769230769230769 2.38961538461538 0.346557201995175 0.583860670941298 GO:0008035 high-density lipoprotein particle binding 1/600 13/18639 0.0769230769230769 2.38961538461538 0.346557201995175 0.583860670941298 GO:0030955 potassium ion binding 1/600 13/18639 0.0769230769230769 2.38961538461538 0.346557201995175 0.583860670941298 GO:0031432 titin binding 1/600 13/18639 0.0769230769230769 2.38961538461538 0.346557201995175 0.583860670941298 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/600 13/18639 0.0769230769230769 2.38961538461538 0.346557201995175 0.583860670941298 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/600 13/18639 0.0769230769230769 2.38961538461538 0.346557201995175 0.583860670941298 GO:0140666 annealing activity 1/600 13/18639 0.0769230769230769 2.38961538461538 0.346557201995175 0.583860670941298 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/600 13/18639 0.0769230769230769 2.38961538461538 0.346557201995175 0.583860670941298 GO:0005501 retinoid binding 2/600 38/18639 0.0526315789473684 1.635 0.347125907095154 0.583860670941298 GO:0019840 isoprenoid binding 2/600 38/18639 0.0526315789473684 1.635 0.347125907095154 0.583860670941298 GO:0019843 rRNA binding 3/600 65/18639 0.0461538461538462 1.43376923076923 0.348729829655714 0.584409879368093 GO:0160215 deacylase activity 3/600 65/18639 0.0461538461538462 1.43376923076923 0.348729829655714 0.584409879368093 GO:0004867 serine-type endopeptidase inhibitor activity 4/600 95/18639 0.0421052631578947 1.308 0.365993048886301 0.5937788003588 GO:0016500 protein-hormone receptor activity 3/600 67/18639 0.0447761194029851 1.39097014925373 0.366407187099177 0.5937788003588 GO:0050840 extracellular matrix binding 3/600 67/18639 0.0447761194029851 1.39097014925373 0.366407187099177 0.5937788003588 GO:0005347 ATP transmembrane transporter activity 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0008195 phosphatidate phosphatase activity 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0008494 translation activator activity 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0008559 ABC-type xenobiotic transporter activity 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0015386 potassium:proton antiporter activity 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0019763 immunoglobulin receptor activity 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0019992 diacylglycerol binding 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0032036 myosin heavy chain binding 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0043176 amine binding 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0046030 inositol trisphosphate phosphatase activity 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0061665 SUMO ligase activity 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0070742 C2H2 zinc finger domain binding 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0071933 Arp2/3 complex binding 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0098847 sequence-specific single stranded DNA binding 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:1901612 cardiolipin binding 1/600 14/18639 0.0714285714285714 2.21892857142857 0.367606578071782 0.5937788003588 GO:0004177 aminopeptidase activity 2/600 40/18639 0.05 1.55325 0.370543928967076 0.5937788003588 GO:0015036 disulfide oxidoreductase activity 2/600 40/18639 0.05 1.55325 0.370543928967076 0.5937788003588 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/600 40/18639 0.05 1.55325 0.370543928967076 0.5937788003588 GO:0050997 quaternary ammonium group binding 2/600 40/18639 0.05 1.55325 0.370543928967076 0.5937788003588 GO:0140662 ATP-dependent protein folding chaperone 2/600 40/18639 0.05 1.55325 0.370543928967076 0.5937788003588 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/600 41/18639 0.0487804878048781 1.51536585365854 0.382128090528718 0.60691915379349 GO:0140318 protein transporter activity 2/600 41/18639 0.0487804878048781 1.51536585365854 0.382128090528718 0.60691915379349 GO:0140828 metal cation:monoatomic cation antiporter activity 2/600 41/18639 0.0487804878048781 1.51536585365854 0.382128090528718 0.60691915379349 GO:0042578 phosphoric ester hydrolase activity 13/600 363/18639 0.0358126721763085 1.11252066115702 0.38707699526979 0.60691915379349 GO:0004129 cytochrome-c oxidase activity 1/600 15/18639 0.0666666666666667 2.071 0.38797898361041 0.60691915379349 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/600 15/18639 0.0666666666666667 2.071 0.38797898361041 0.60691915379349 GO:0015929 hexosaminidase activity 1/600 15/18639 0.0666666666666667 2.071 0.38797898361041 0.60691915379349 GO:0016846 carbon-sulfur lyase activity 1/600 15/18639 0.0666666666666667 2.071 0.38797898361041 0.60691915379349 GO:0031005 filamin binding 1/600 15/18639 0.0666666666666667 2.071 0.38797898361041 0.60691915379349 GO:0045504 dynein heavy chain binding 1/600 15/18639 0.0666666666666667 2.071 0.38797898361041 0.60691915379349 GO:0061578 K63-linked deubiquitinase activity 1/600 15/18639 0.0666666666666667 2.071 0.38797898361041 0.60691915379349 GO:0120283 protein serine/threonine kinase binding 1/600 15/18639 0.0666666666666667 2.071 0.38797898361041 0.60691915379349 GO:0004725 protein tyrosine phosphatase activity 4/600 98/18639 0.0408163265306122 1.26795918367347 0.38800036034587 0.60691915379349 GO:0004519 endonuclease activity 5/600 127/18639 0.0393700787401575 1.22303149606299 0.388693578276487 0.60691915379349 GO:0019783 ubiquitin-like protein peptidase activity 5/600 127/18639 0.0393700787401575 1.22303149606299 0.388693578276487 0.60691915379349 GO:0008307 structural constituent of muscle 2/600 42/18639 0.0476190476190476 1.47928571428571 0.393620067129014 0.612521022828313 GO:0043175 RNA polymerase core enzyme binding 2/600 42/18639 0.0476190476190476 1.47928571428571 0.393620067129014 0.612521022828313 GO:0043130 ubiquitin binding 4/600 100/18639 0.04 1.2426 0.402618046772861 0.621001841203058 GO:0008375 acetylglucosaminyltransferase activity 2/600 43/18639 0.0465116279069767 1.44488372093023 0.405013790017451 0.621001841203058 GO:0000062 fatty-acyl-CoA binding 1/600 16/18639 0.0625 1.9415625 0.407696155530177 0.621001841203058 GO:0004708 MAP kinase kinase activity 1/600 16/18639 0.0625 1.9415625 0.407696155530177 0.621001841203058 GO:0005159 insulin-like growth factor receptor binding 1/600 16/18639 0.0625 1.9415625 0.407696155530177 0.621001841203058 GO:0008296 3'-5'-DNA exonuclease activity 1/600 16/18639 0.0625 1.9415625 0.407696155530177 0.621001841203058 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/600 16/18639 0.0625 1.9415625 0.407696155530177 0.621001841203058 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/600 16/18639 0.0625 1.9415625 0.407696155530177 0.621001841203058 GO:0017070 U6 snRNA binding 1/600 16/18639 0.0625 1.9415625 0.407696155530177 0.621001841203058 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/600 16/18639 0.0625 1.9415625 0.407696155530177 0.621001841203058 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/600 16/18639 0.0625 1.9415625 0.407696155530177 0.621001841203058 GO:0140328 floppase activity 1/600 16/18639 0.0625 1.9415625 0.407696155530177 0.621001841203058 GO:0016298 lipase activity 5/600 130/18639 0.0384615384615385 1.19480769230769 0.4078930126372 0.621001841203058 GO:0005518 collagen binding 3/600 72/18639 0.0416666666666667 1.294375 0.410168764430153 0.623429268195332 GO:0099106 ion channel regulator activity 6/600 160/18639 0.0375 1.1649375 0.410935329042712 0.623558583870782 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/600 44/18639 0.0454545454545455 1.41204545454545 0.416303675266047 0.630658713358332 GO:0004722 protein serine/threonine phosphatase activity 4/600 103/18639 0.0388349514563107 1.20640776699029 0.424417925574924 0.63292622657888 GO:0004550 nucleoside diphosphate kinase activity 1/600 17/18639 0.0588235294117647 1.82735294117647 0.426779133926885 0.63292622657888 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/600 17/18639 0.0588235294117647 1.82735294117647 0.426779133926885 0.63292622657888 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/600 17/18639 0.0588235294117647 1.82735294117647 0.426779133926885 0.63292622657888 GO:0015278 intracellularly gated calcium channel activity 1/600 17/18639 0.0588235294117647 1.82735294117647 0.426779133926885 0.63292622657888 GO:0016018 cyclosporin A binding 1/600 17/18639 0.0588235294117647 1.82735294117647 0.426779133926885 0.63292622657888 GO:0019198 transmembrane receptor protein phosphatase activity 1/600 17/18639 0.0588235294117647 1.82735294117647 0.426779133926885 0.63292622657888 GO:0036041 long-chain fatty acid binding 1/600 17/18639 0.0588235294117647 1.82735294117647 0.426779133926885 0.63292622657888 GO:0038191 neuropilin binding 1/600 17/18639 0.0588235294117647 1.82735294117647 0.426779133926885 0.63292622657888 GO:0048038 quinone binding 1/600 17/18639 0.0588235294117647 1.82735294117647 0.426779133926885 0.63292622657888 GO:1901567 fatty acid derivative binding 1/600 17/18639 0.0588235294117647 1.82735294117647 0.426779133926885 0.63292622657888 GO:0003678 DNA helicase activity 3/600 74/18639 0.0405405405405405 1.25939189189189 0.427424132066108 0.63292622657888 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/600 45/18639 0.0444444444444444 1.38066666666667 0.427484598935244 0.63292622657888 GO:0140303 intramembrane lipid transporter activity 2/600 45/18639 0.0444444444444444 1.38066666666667 0.427484598935244 0.63292622657888 GO:0004180 carboxypeptidase activity 2/600 46/18639 0.0434782608695652 1.35065217391304 0.438551873331908 0.645645293507258 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/600 46/18639 0.0434782608695652 1.35065217391304 0.438551873331908 0.645645293507258 GO:0030276 clathrin binding 2/600 46/18639 0.0434782608695652 1.35065217391304 0.438551873331908 0.645645293507258 GO:0000400 four-way junction DNA binding 1/600 18/18639 0.0555555555555556 1.72583333333333 0.445248284374951 0.645645293507258 GO:0000900 mRNA regulatory element binding translation repressor activity 1/600 18/18639 0.0555555555555556 1.72583333333333 0.445248284374951 0.645645293507258 GO:0008409 5'-3' exonuclease activity 1/600 18/18639 0.0555555555555556 1.72583333333333 0.445248284374951 0.645645293507258 GO:0015172 acidic amino acid transmembrane transporter activity 1/600 18/18639 0.0555555555555556 1.72583333333333 0.445248284374951 0.645645293507258 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/600 18/18639 0.0555555555555556 1.72583333333333 0.445248284374951 0.645645293507258 GO:0017128 phospholipid scramblase activity 1/600 18/18639 0.0555555555555556 1.72583333333333 0.445248284374951 0.645645293507258 GO:0031690 adrenergic receptor binding 1/600 18/18639 0.0555555555555556 1.72583333333333 0.445248284374951 0.645645293507258 GO:0034185 apolipoprotein binding 1/600 18/18639 0.0555555555555556 1.72583333333333 0.445248284374951 0.645645293507258 GO:0035615 clathrin adaptor activity 1/600 18/18639 0.0555555555555556 1.72583333333333 0.445248284374951 0.645645293507258 GO:0070064 proline-rich region binding 1/600 18/18639 0.0555555555555556 1.72583333333333 0.445248284374951 0.645645293507258 GO:0140789 histone phosphatase activity 5/600 136/18639 0.0367647058823529 1.14209558823529 0.44600636290841 0.6457212374386 GO:0005504 fatty acid binding 2/600 47/18639 0.0425531914893617 1.32191489361702 0.449501224315046 0.649752954578621 GO:0005201 extracellular matrix structural constituent 6/600 168/18639 0.0357142857142857 1.10946428571429 0.45669888548292 0.652032319561951 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 8/600 229/18639 0.0349344978165939 1.08524017467249 0.457690817672812 0.652032319561951 GO:0036121 double-stranded DNA helicase activity 2/600 48/18639 0.0416666666666667 1.294375 0.460328769606566 0.652032319561951 GO:0019199 transmembrane receptor protein kinase activity 3/600 78/18639 0.0384615384615385 1.19480769230769 0.461367827927439 0.652032319561951 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/600 19/18639 0.0526315789473684 1.635 0.463123319516727 0.652032319561951 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/600 19/18639 0.0526315789473684 1.635 0.463123319516727 0.652032319561951 GO:0005520 insulin-like growth factor binding 1/600 19/18639 0.0526315789473684 1.635 0.463123319516727 0.652032319561951 GO:0022821 solute:potassium antiporter activity 1/600 19/18639 0.0526315789473684 1.635 0.463123319516727 0.652032319561951 GO:0030506 ankyrin binding 1/600 19/18639 0.0526315789473684 1.635 0.463123319516727 0.652032319561951 GO:0031420 alkali metal ion binding 1/600 19/18639 0.0526315789473684 1.635 0.463123319516727 0.652032319561951 GO:0042577 lipid phosphatase activity 1/600 19/18639 0.0526315789473684 1.635 0.463123319516727 0.652032319561951 GO:0046624 sphingolipid transporter activity 1/600 19/18639 0.0526315789473684 1.635 0.463123319516727 0.652032319561951 GO:0050145 nucleoside monophosphate kinase activity 1/600 19/18639 0.0526315789473684 1.635 0.463123319516727 0.652032319561951 GO:0070003 threonine-type peptidase activity 1/600 19/18639 0.0526315789473684 1.635 0.463123319516727 0.652032319561951 GO:0120227 acyl-CoA binding 1/600 19/18639 0.0526315789473684 1.635 0.463123319516727 0.652032319561951 GO:1990380 K48-linked deubiquitinase activity 1/600 19/18639 0.0526315789473684 1.635 0.463123319516727 0.652032319561951 GO:0016829 lyase activity 7/600 200/18639 0.035 1.087275 0.465189368901647 0.652032319561951 GO:0001222 transcription corepressor binding 2/600 49/18639 0.0408163265306122 1.26795918367347 0.471030998066065 0.652032319561951 GO:0005004 GPI-linked ephrin receptor activity 2/600 49/18639 0.0408163265306122 1.26795918367347 0.471030998066065 0.652032319561951 GO:0005008 hepatocyte growth factor receptor activity 2/600 49/18639 0.0408163265306122 1.26795918367347 0.471030998066065 0.652032319561951 GO:0005009 insulin receptor activity 2/600 49/18639 0.0408163265306122 1.26795918367347 0.471030998066065 0.652032319561951 GO:0005011 macrophage colony-stimulating factor receptor activity 2/600 49/18639 0.0408163265306122 1.26795918367347 0.471030998066065 0.652032319561951 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/600 49/18639 0.0408163265306122 1.26795918367347 0.471030998066065 0.652032319561951 GO:0005020 stem cell factor receptor activity 2/600 49/18639 0.0408163265306122 1.26795918367347 0.471030998066065 0.652032319561951 GO:0008288 boss receptor activity 2/600 49/18639 0.0408163265306122 1.26795918367347 0.471030998066065 0.652032319561951 GO:0036332 placental growth factor receptor activity 2/600 49/18639 0.0408163265306122 1.26795918367347 0.471030998066065 0.652032319561951 GO:0038062 protein tyrosine kinase collagen receptor activity 2/600 49/18639 0.0408163265306122 1.26795918367347 0.471030998066065 0.652032319561951 GO:0060175 brain-derived neurotrophic factor receptor activity 2/600 49/18639 0.0408163265306122 1.26795918367347 0.471030998066065 0.652032319561951 GO:0001614 purinergic nucleotide receptor activity 1/600 20/18639 0.05 1.55325 0.480423319961946 0.65575646748444 GO:0016502 nucleotide receptor activity 1/600 20/18639 0.05 1.55325 0.480423319961946 0.65575646748444 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/600 20/18639 0.05 1.55325 0.480423319961946 0.65575646748444 GO:0031418 L-ascorbic acid binding 1/600 20/18639 0.05 1.55325 0.480423319961946 0.65575646748444 GO:0043024 ribosomal small subunit binding 1/600 20/18639 0.05 1.55325 0.480423319961946 0.65575646748444 GO:0052745 inositol phosphate phosphatase activity 1/600 20/18639 0.05 1.55325 0.480423319961946 0.65575646748444 GO:0005006 epidermal growth factor receptor activity 2/600 50/18639 0.04 1.2426 0.481604749890212 0.65575646748444 GO:0005007 fibroblast growth factor receptor activity 2/600 50/18639 0.04 1.2426 0.481604749890212 0.65575646748444 GO:0005017 platelet-derived growth factor receptor activity 2/600 50/18639 0.04 1.2426 0.481604749890212 0.65575646748444 GO:0005019 platelet-derived growth factor beta-receptor activity 2/600 50/18639 0.04 1.2426 0.481604749890212 0.65575646748444 GO:0015605 organophosphate ester transmembrane transporter activity 2/600 50/18639 0.04 1.2426 0.481604749890212 0.65575646748444 GO:0015101 organic cation transmembrane transporter activity 3/600 81/18639 0.037037037037037 1.15055555555556 0.486244534281794 0.661090265776881 GO:0005021 vascular endothelial growth factor receptor activity 2/600 51/18639 0.0392156862745098 1.21823529411765 0.492047197698835 0.666010630021352 GO:0005030 neurotrophin receptor activity 2/600 51/18639 0.0392156862745098 1.21823529411765 0.492047197698835 0.666010630021352 GO:0005048 signal sequence binding 2/600 51/18639 0.0392156862745098 1.21823529411765 0.492047197698835 0.666010630021352 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/600 21/18639 0.0476190476190476 1.47928571428571 0.497166754519271 0.668981735860489 GO:0001846 opsonin binding 1/600 21/18639 0.0476190476190476 1.47928571428571 0.497166754519271 0.668981735860489 GO:0036122 BMP binding 1/600 21/18639 0.0476190476190476 1.47928571428571 0.497166754519271 0.668981735860489 GO:0140312 cargo adaptor activity 1/600 21/18639 0.0476190476190476 1.47928571428571 0.497166754519271 0.668981735860489 GO:0005516 calmodulin binding 7/600 207/18639 0.0338164251207729 1.05050724637681 0.501280876503135 0.67352716886985 GO:0004864 protein phosphatase inhibitor activity 2/600 53/18639 0.0377358490566038 1.1722641509434 0.512528426298197 0.681763312481695 GO:0005003 ephrin receptor activity 2/600 53/18639 0.0377358490566038 1.1722641509434 0.512528426298197 0.681763312481695 GO:0005005 transmembrane-ephrin receptor activity 2/600 53/18639 0.0377358490566038 1.1722641509434 0.512528426298197 0.681763312481695 GO:0005246 calcium channel regulator activity 2/600 53/18639 0.0377358490566038 1.1722641509434 0.512528426298197 0.681763312481695 GO:0051018 protein kinase A binding 2/600 53/18639 0.0377358490566038 1.1722641509434 0.512528426298197 0.681763312481695 GO:0008093 cytoskeletal anchor activity 1/600 22/18639 0.0454545454545455 1.41204545454545 0.513371499781298 0.681763312481695 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/600 22/18639 0.0454545454545455 1.41204545454545 0.513371499781298 0.681763312481695 GO:0033691 sialic acid binding 1/600 22/18639 0.0454545454545455 1.41204545454545 0.513371499781298 0.681763312481695 GO:0016791 phosphatase activity 9/600 273/18639 0.032967032967033 1.02412087912088 0.518608899679849 0.686645668172351 GO:0015485 cholesterol binding 2/600 54/18639 0.037037037037037 1.15055555555556 0.522563055914613 0.686645668172351 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/600 54/18639 0.037037037037037 1.15055555555556 0.522563055914613 0.686645668172351 GO:0050661 NADP binding 2/600 54/18639 0.037037037037037 1.15055555555556 0.522563055914613 0.686645668172351 GO:0140463 chromatin-protein adaptor activity 2/600 54/18639 0.037037037037037 1.15055555555556 0.522563055914613 0.686645668172351 GO:0016853 isomerase activity 6/600 180/18639 0.0333333333333333 1.0355 0.523520644983198 0.686645668172351 GO:0019001 guanyl nucleotide binding 13/600 400/18639 0.0325 1.0096125 0.525851987890031 0.686645668172351 GO:0032561 guanyl ribonucleotide binding 13/600 400/18639 0.0325 1.0096125 0.525851987890031 0.686645668172351 GO:0046982 protein heterodimerization activity 12/600 369/18639 0.032520325203252 1.01024390243902 0.527074478108557 0.686645668172351 GO:0004602 glutathione peroxidase activity 1/600 23/18639 0.0434782608695652 1.35065217391304 0.529054859083615 0.686645668172351 GO:0005212 structural constituent of eye lens 1/600 23/18639 0.0434782608695652 1.35065217391304 0.529054859083615 0.686645668172351 GO:0005283 amino acid:sodium symporter activity 1/600 23/18639 0.0434782608695652 1.35065217391304 0.529054859083615 0.686645668172351 GO:0016493 C-C chemokine receptor activity 1/600 23/18639 0.0434782608695652 1.35065217391304 0.529054859083615 0.686645668172351 GO:0016849 phosphorus-oxygen lyase activity 1/600 23/18639 0.0434782608695652 1.35065217391304 0.529054859083615 0.686645668172351 GO:0016917 GABA receptor activity 1/600 23/18639 0.0434782608695652 1.35065217391304 0.529054859083615 0.686645668172351 GO:0140103 catalytic activity, acting on a glycoprotein 1/600 23/18639 0.0434782608695652 1.35065217391304 0.529054859083615 0.686645668172351 GO:0008017 microtubule binding 9/600 276/18639 0.0326086956521739 1.01298913043478 0.531844035350012 0.689287949497536 GO:0001217 DNA-binding transcription repressor activity 9/600 278/18639 0.0323741007194245 1.00570143884892 0.540595766646828 0.696466750328624 GO:0019212 phosphatase inhibitor activity 2/600 56/18639 0.0357142857142857 1.10946428571429 0.542211979093333 0.696466750328624 GO:0032182 ubiquitin-like protein binding 4/600 120/18639 0.0333333333333333 1.0355 0.54269363618956 0.696466750328624 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/600 24/18639 0.0416666666666667 1.294375 0.544233580857886 0.696466750328624 GO:0004806 triacylglycerol lipase activity 1/600 24/18639 0.0416666666666667 1.294375 0.544233580857886 0.696466750328624 GO:0005315 phosphate transmembrane transporter activity 1/600 24/18639 0.0416666666666667 1.294375 0.544233580857886 0.696466750328624 GO:0019957 C-C chemokine binding 1/600 24/18639 0.0416666666666667 1.294375 0.544233580857886 0.696466750328624 GO:0050699 WW domain binding 1/600 24/18639 0.0416666666666667 1.294375 0.544233580857886 0.696466750328624 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/600 24/18639 0.0416666666666667 1.294375 0.544233580857886 0.696466750328624 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/600 57/18639 0.0350877192982456 1.09 0.551823667454052 0.705193653240862 GO:0001848 complement binding 1/600 25/18639 0.04 1.2426 0.558923876398325 0.710299092922871 GO:0003707 nuclear steroid receptor activity 1/600 25/18639 0.04 1.2426 0.558923876398325 0.710299092922871 GO:0005251 delayed rectifier potassium channel activity 1/600 25/18639 0.04 1.2426 0.558923876398325 0.710299092922871 GO:0008139 nuclear localization sequence binding 1/600 25/18639 0.04 1.2426 0.558923876398325 0.710299092922871 GO:0005525 GTP binding 12/600 378/18639 0.0317460317460317 0.986190476190476 0.560973162383726 0.711914623552163 GO:0035091 phosphatidylinositol binding 9/600 284/18639 0.0316901408450704 0.984454225352113 0.566469815417766 0.717894572170714 GO:0031593 polyubiquitin modification-dependent protein binding 2/600 59/18639 0.0338983050847458 1.05305084745763 0.570616670573243 0.719375054746399 GO:0001637 G protein-coupled chemoattractant receptor activity 1/600 26/18639 0.0384615384615385 1.19480769230769 0.573141437060246 0.719375054746399 GO:0004950 chemokine receptor activity 1/600 26/18639 0.0384615384615385 1.19480769230769 0.573141437060246 0.719375054746399 GO:0005112 Notch binding 1/600 26/18639 0.0384615384615385 1.19480769230769 0.573141437060246 0.719375054746399 GO:0008198 ferrous iron binding 1/600 26/18639 0.0384615384615385 1.19480769230769 0.573141437060246 0.719375054746399 GO:0050681 nuclear androgen receptor binding 1/600 26/18639 0.0384615384615385 1.19480769230769 0.573141437060246 0.719375054746399 GO:0097602 cullin family protein binding 1/600 26/18639 0.0384615384615385 1.19480769230769 0.573141437060246 0.719375054746399 GO:0051213 dioxygenase activity 3/600 93/18639 0.032258064516129 1.00209677419355 0.579604316938269 0.72375710342887 GO:0001098 basal transcription machinery binding 2/600 60/18639 0.0333333333333333 1.0355 0.579796674112964 0.72375710342887 GO:0001099 basal RNA polymerase II transcription machinery binding 2/600 60/18639 0.0333333333333333 1.0355 0.579796674112964 0.72375710342887 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/600 60/18639 0.0333333333333333 1.0355 0.579796674112964 0.72375710342887 GO:0004364 glutathione transferase activity 1/600 27/18639 0.037037037037037 1.15055555555556 0.586901450908839 0.728649698211109 GO:0008395 steroid hydroxylase activity 1/600 27/18639 0.037037037037037 1.15055555555556 0.586901450908839 0.728649698211109 GO:0016405 CoA-ligase activity 1/600 27/18639 0.037037037037037 1.15055555555556 0.586901450908839 0.728649698211109 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/600 27/18639 0.037037037037037 1.15055555555556 0.586901450908839 0.728649698211109 GO:0015026 coreceptor activity 2/600 61/18639 0.0327868852459016 1.01852459016393 0.588831787220311 0.730055671147134 GO:0004866 endopeptidase inhibitor activity 5/600 161/18639 0.031055900621118 0.964751552795031 0.595082011311549 0.736806549864773 GO:0005242 inward rectifier potassium channel activity 1/600 28/18639 0.0357142857142857 1.10946428571429 0.600218618835697 0.739165593855536 GO:0046966 nuclear thyroid hormone receptor binding 1/600 28/18639 0.0357142857142857 1.10946428571429 0.600218618835697 0.739165593855536 GO:0051393 alpha-actinin binding 1/600 28/18639 0.0357142857142857 1.10946428571429 0.600218618835697 0.739165593855536 GO:0141052 histone H3 demethylase activity 1/600 28/18639 0.0357142857142857 1.10946428571429 0.600218618835697 0.739165593855536 GO:1901682 sulfur compound transmembrane transporter activity 2/600 63/18639 0.0317460317460317 0.986190476190476 0.606466707973405 0.745856233596325 GO:0000287 magnesium ion binding 7/600 230/18639 0.0304347826086957 0.94545652173913 0.612984419379769 0.746001410500662 GO:0003785 actin monomer binding 1/600 29/18639 0.0344827586206897 1.07120689655172 0.613107170160107 0.746001410500662 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/600 29/18639 0.0344827586206897 1.07120689655172 0.613107170160107 0.746001410500662 GO:0005416 amino acid:monoatomic cation symporter activity 1/600 29/18639 0.0344827586206897 1.07120689655172 0.613107170160107 0.746001410500662 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/600 29/18639 0.0344827586206897 1.07120689655172 0.613107170160107 0.746001410500662 GO:0097472 cyclin-dependent protein kinase activity 1/600 29/18639 0.0344827586206897 1.07120689655172 0.613107170160107 0.746001410500662 GO:0099604 ligand-gated calcium channel activity 1/600 29/18639 0.0344827586206897 1.07120689655172 0.613107170160107 0.746001410500662 GO:0106222 lncRNA binding 1/600 29/18639 0.0344827586206897 1.07120689655172 0.613107170160107 0.746001410500662 GO:0004536 DNA nuclease activity 2/600 64/18639 0.03125 0.97078125 0.615066595010424 0.747391679195934 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/600 132/18639 0.0303030303030303 0.941363636363636 0.618171299999018 0.750168089521355 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/600 30/18639 0.0333333333333333 1.0355 0.625580877731517 0.754158765644714 GO:0008187 poly-pyrimidine tract binding 1/600 30/18639 0.0333333333333333 1.0355 0.625580877731517 0.754158765644714 GO:0032452 histone demethylase activity 1/600 30/18639 0.0333333333333333 1.0355 0.625580877731517 0.754158765644714 GO:0033612 receptor serine/threonine kinase binding 1/600 30/18639 0.0333333333333333 1.0355 0.625580877731517 0.754158765644714 GO:0051721 protein phosphatase 2A binding 1/600 30/18639 0.0333333333333333 1.0355 0.625580877731517 0.754158765644714 GO:0008235 metalloexopeptidase activity 2/600 66/18639 0.0303030303030303 0.941363636363636 0.631832506247814 0.759946288930544 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 8/600 268/18639 0.0298507462686567 0.927313432835821 0.635518762988313 0.759946288930544 GO:0005452 solute:inorganic anion antiporter activity 1/600 31/18639 0.032258064516129 1.00209677419355 0.637653072549137 0.759946288930544 GO:0008327 methyl-CpG binding 1/600 31/18639 0.032258064516129 1.00209677419355 0.637653072549137 0.759946288930544 GO:0016878 acid-thiol ligase activity 1/600 31/18639 0.032258064516129 1.00209677419355 0.637653072549137 0.759946288930544 GO:0047499 calcium-independent phospholipase A2 activity 1/600 31/18639 0.032258064516129 1.00209677419355 0.637653072549137 0.759946288930544 GO:0070273 phosphatidylinositol-4-phosphate binding 1/600 31/18639 0.032258064516129 1.00209677419355 0.637653072549137 0.759946288930544 GO:0140457 protein demethylase activity 1/600 31/18639 0.032258064516129 1.00209677419355 0.637653072549137 0.759946288930544 GO:0030414 peptidase inhibitor activity 5/600 169/18639 0.029585798816568 0.919082840236686 0.637856557266293 0.759946288930544 GO:0008238 exopeptidase activity 3/600 102/18639 0.0294117647058824 0.913676470588235 0.642186780363299 0.76311805718496 GO:0015171 amino acid transmembrane transporter activity 3/600 102/18639 0.0294117647058824 0.913676470588235 0.642186780363299 0.76311805718496 GO:0032934 sterol binding 2/600 68/18639 0.0294117647058824 0.913676470588235 0.648023161950396 0.765648249988874 GO:0031369 translation initiation factor binding 1/600 32/18639 0.03125 0.97078125 0.649336657914061 0.765648249988874 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/600 32/18639 0.03125 0.97078125 0.649336657914061 0.765648249988874 GO:0042910 xenobiotic transmembrane transporter activity 1/600 32/18639 0.03125 0.97078125 0.649336657914061 0.765648249988874 GO:0047498 calcium-dependent phospholipase A2 activity 1/600 32/18639 0.03125 0.97078125 0.649336657914061 0.765648249988874 GO:0051059 NF-kappaB binding 1/600 32/18639 0.03125 0.97078125 0.649336657914061 0.765648249988874 GO:0002039 p53 binding 2/600 69/18639 0.0289855072463768 0.900434782608696 0.655904415709953 0.772397091859211 GO:0019956 chemokine binding 1/600 33/18639 0.0303030303030303 0.941363636363636 0.660644123128849 0.775981222930548 GO:0042923 neuropeptide binding 1/600 33/18639 0.0303030303030303 0.941363636363636 0.660644123128849 0.775981222930548 GO:0004721 phosphoprotein phosphatase activity 5/600 175/18639 0.0285714285714286 0.887571428571428 0.66804316135496 0.783666016204857 GO:0008175 tRNA methyltransferase activity 1/600 34/18639 0.0294117647058824 0.913676470588235 0.671587556759006 0.783804355146034 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/600 34/18639 0.0294117647058824 0.913676470588235 0.671587556759006 0.783804355146034 GO:0016831 carboxy-lyase activity 1/600 34/18639 0.0294117647058824 0.913676470588235 0.671587556759006 0.783804355146034 GO:0051427 hormone receptor binding 1/600 34/18639 0.0294117647058824 0.913676470588235 0.671587556759006 0.783804355146034 GO:0005496 steroid binding 3/600 108/18639 0.0277777777777778 0.862916666666667 0.680105587990705 0.791119738169039 GO:0004623 phospholipase A2 activity 1/600 35/18639 0.0285714285714286 0.887571428571428 0.682178659470352 0.791119738169039 GO:0005343 organic acid:sodium symporter activity 1/600 35/18639 0.0285714285714286 0.887571428571428 0.682178659470352 0.791119738169039 GO:0016229 steroid dehydrogenase activity 1/600 35/18639 0.0285714285714286 0.887571428571428 0.682178659470352 0.791119738169039 GO:0061631 ubiquitin conjugating enzyme activity 1/600 35/18639 0.0285714285714286 0.887571428571428 0.682178659470352 0.791119738169039 GO:0004190 aspartic-type endopeptidase activity 1/600 36/18639 0.0277777777777778 0.862916666666667 0.692428756455828 0.801875731228693 GO:0035064 methylated histone binding 2/600 74/18639 0.027027027027027 0.839594594594595 0.693206233226116 0.801875731228693 GO:0015631 tubulin binding 11/600 385/18639 0.0285714285714286 0.887571428571428 0.698889126268388 0.807428725423706 GO:0042805 actinin binding 1/600 37/18639 0.027027027027027 0.839594594594595 0.702348809464832 0.809381814433654 GO:0070001 aspartic-type peptidase activity 1/600 37/18639 0.027027027027027 0.839594594594595 0.702348809464832 0.809381814433654 GO:0140034 methylation-dependent protein binding 2/600 76/18639 0.0263157894736842 0.8175 0.707165687121495 0.8139076776304 GO:0000146 microfilament motor activity 1/600 38/18639 0.0263157894736842 0.8175 0.711949428447796 0.818384079183082 GO:1901981 phosphatidylinositol phosphate binding 5/600 185/18639 0.027027027027027 0.839594594594595 0.714573383623504 0.819378480380411 GO:0022804 active transmembrane transporter activity 13/600 457/18639 0.0284463894967177 0.883687089715536 0.714605494364555 0.819378480380411 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/600 39/18639 0.0256410256410256 0.796538461538462 0.721240882828277 0.824919259734841 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/600 39/18639 0.0256410256410256 0.796538461538462 0.721240882828277 0.824919259734841 GO:0030331 nuclear estrogen receptor binding 1/600 40/18639 0.025 0.776625 0.730233112414462 0.828986721909718 GO:0032451 demethylase activity 1/600 40/18639 0.025 0.776625 0.730233112414462 0.828986721909718 GO:0061791 GTPase motor activity 1/600 40/18639 0.025 0.776625 0.730233112414462 0.828986721909718 GO:0071855 neuropeptide receptor binding 1/600 40/18639 0.025 0.776625 0.730233112414462 0.828986721909718 GO:0071949 FAD binding 1/600 40/18639 0.025 0.776625 0.730233112414462 0.828986721909718 GO:1990606 membrane scission GTPase motor activity 1/600 40/18639 0.025 0.776625 0.730233112414462 0.828986721909718 GO:0000049 tRNA binding 2/600 80/18639 0.025 0.776625 0.733494462433343 0.83165729011959 GO:0005506 iron ion binding 4/600 154/18639 0.025974025974026 0.806883116883117 0.734654781856639 0.831941986879733 GO:0001727 lipid kinase activity 1/600 41/18639 0.024390243902439 0.757682926829268 0.738935737961605 0.833694451584301 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/600 41/18639 0.024390243902439 0.757682926829268 0.738935737961605 0.833694451584301 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/600 41/18639 0.024390243902439 0.757682926829268 0.738935737961605 0.833694451584301 GO:0003730 mRNA 3'-UTR binding 7/600 262/18639 0.0267175572519084 0.829980916030534 0.742903043317228 0.837138281570522 GO:0019894 kinesin binding 1/600 42/18639 0.0238095238095238 0.739642857142857 0.747358071396546 0.839058448255018 GO:0031492 nucleosomal DNA binding 1/600 42/18639 0.0238095238095238 0.739642857142857 0.747358071396546 0.839058448255018 GO:0048487 beta-tubulin binding 1/600 42/18639 0.0238095238095238 0.739642857142857 0.747358071396546 0.839058448255018 GO:0003697 single-stranded DNA binding 3/600 121/18639 0.0247933884297521 0.770206611570248 0.751831173599097 0.842087389890014 GO:0030165 PDZ domain binding 2/600 83/18639 0.0240963855421687 0.74855421686747 0.751896609333488 0.842087389890014 GO:0008528 G protein-coupled peptide receptor activity 3/600 122/18639 0.0245901639344262 0.763893442622951 0.756773035913077 0.845479032796661 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/600 122/18639 0.0245901639344262 0.763893442622951 0.756773035913077 0.845479032796661 GO:0015079 potassium ion transmembrane transporter activity 4/600 160/18639 0.025 0.776625 0.761317151466151 0.849518528770157 GO:0001223 transcription coactivator binding 1/600 44/18639 0.0227272727272727 0.706022727272727 0.763397624562749 0.8497674288016 GO:0019205 nucleobase-containing compound kinase activity 1/600 44/18639 0.0227272727272727 0.706022727272727 0.763397624562749 0.8497674288016 GO:0005267 potassium channel activity 3/600 124/18639 0.0241935483870968 0.751572580645161 0.766418526787124 0.852093501835017 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/600 86/18639 0.0232558139534884 0.722441860465116 0.76919428639052 0.853106390360395 GO:0050660 flavin adenine dinucleotide binding 2/600 86/18639 0.0232558139534884 0.722441860465116 0.76919428639052 0.853106390360395 GO:0051539 4 iron, 4 sulfur cluster binding 1/600 45/18639 0.0222222222222222 0.690333333333333 0.771032011508828 0.854109310569707 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/600 46/18639 0.0217391304347826 0.675326086956522 0.778420459023871 0.86125117292242 GO:0001653 peptide receptor activity 3/600 128/18639 0.0234375 0.7280859375 0.784774833737111 0.864978763670625 GO:0043495 protein-membrane adaptor activity 1/600 47/18639 0.0212765957446809 0.660957446808511 0.785570877169715 0.864978763670625 GO:0061749 forked DNA-dependent helicase activity 1/600 47/18639 0.0212765957446809 0.660957446808511 0.785570877169715 0.864978763670625 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/600 47/18639 0.0212765957446809 0.660957446808511 0.785570877169715 0.864978763670625 GO:0016874 ligase activity 4/600 167/18639 0.0239520958083832 0.744071856287425 0.789741630092557 0.867379418230272 GO:0009378 four-way junction helicase activity 1/600 48/18639 0.0208333333333333 0.6471875 0.792490922011484 0.867379418230272 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/600 48/18639 0.0208333333333333 0.6471875 0.792490922011484 0.867379418230272 GO:0032266 phosphatidylinositol-3-phosphate binding 1/600 48/18639 0.0208333333333333 0.6471875 0.792490922011484 0.867379418230272 GO:0043138 3'-5' DNA helicase activity 1/600 48/18639 0.0208333333333333 0.6471875 0.792490922011484 0.867379418230272 GO:0016798 hydrolase activity, acting on glycosyl bonds 3/600 130/18639 0.0230769230769231 0.716884615384615 0.793496769465348 0.867442704971079 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/600 91/18639 0.021978021978022 0.682747252747253 0.795692906488256 0.868805500521187 GO:0043178 alcohol binding 2/600 92/18639 0.0217391304347826 0.675326086956522 0.800658536907004 0.873185412717412 GO:0042562 hormone binding 2/600 94/18639 0.0212765957446809 0.660957446808511 0.810269658286856 0.880244892161415 GO:0003743 translation initiation factor activity 1/600 51/18639 0.0196078431372549 0.609117647058823 0.811941736594792 0.880244892161415 GO:0005272 sodium channel activity 1/600 51/18639 0.0196078431372549 0.609117647058823 0.811941736594792 0.880244892161415 GO:0016597 amino acid binding 1/600 51/18639 0.0196078431372549 0.609117647058823 0.811941736594792 0.880244892161415 GO:0016830 carbon-carbon lyase activity 1/600 51/18639 0.0196078431372549 0.609117647058823 0.811941736594792 0.880244892161415 GO:0015297 antiporter activity 3/600 135/18639 0.0222222222222222 0.690333333333333 0.81401881378985 0.881452324991376 GO:0005544 calcium-dependent phospholipid binding 1/600 53/18639 0.0188679245283019 0.586132075471698 0.823886733561486 0.887934465499128 GO:0008146 sulfotransferase activity 1/600 53/18639 0.0188679245283019 0.586132075471698 0.823886733561486 0.887934465499128 GO:0017046 peptide hormone binding 1/600 53/18639 0.0188679245283019 0.586132075471698 0.823886733561486 0.887934465499128 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/600 53/18639 0.0188679245283019 0.586132075471698 0.823886733561486 0.887934465499128 GO:0005249 voltage-gated potassium channel activity 2/600 98/18639 0.0204081632653061 0.633979591836735 0.828260217993051 0.890550058124138 GO:0030527 structural constituent of chromatin 2/600 98/18639 0.0204081632653061 0.633979591836735 0.828260217993051 0.890550058124138 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/600 181/18639 0.0220994475138122 0.686519337016575 0.838424247936083 0.900420407114455 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/600 56/18639 0.0178571428571429 0.554732142857143 0.840398965415914 0.900427462945622 GO:0170055 lipid transmembrane transporter activity 1/600 56/18639 0.0178571428571429 0.554732142857143 0.840398965415914 0.900427462945622 GO:0017116 single-stranded DNA helicase activity 1/600 58/18639 0.0172413793103448 0.535603448275862 0.850539112341871 0.910226067593932 GO:0036002 pre-mRNA binding 1/600 59/18639 0.0169491525423729 0.526525423728814 0.855365361337882 0.914321618719815 GO:0004497 monooxygenase activity 2/600 106/18639 0.0188679245283019 0.586132075471698 0.859700466023712 0.916103557164151 GO:0008013 beta-catenin binding 2/600 106/18639 0.0188679245283019 0.586132075471698 0.859700466023712 0.916103557164151 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/600 60/18639 0.0166666666666667 0.51775 0.860036017053559 0.916103557164151 GO:0016757 glycosyltransferase activity 6/600 267/18639 0.0224719101123595 0.698089887640449 0.863480774706882 0.918703382391624 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/600 61/18639 0.0163934426229508 0.509262295081967 0.864556087550779 0.918779117432013 GO:0005507 copper ion binding 1/600 63/18639 0.0158730158730159 0.493095238095238 0.873163705635619 0.926850105170059 GO:1902936 phosphatidylinositol bisphosphate binding 2/600 111/18639 0.018018018018018 0.55972972972973 0.876583683323665 0.929402167139228 GO:0008173 RNA methyltransferase activity 1/600 67/18639 0.0149253731343284 0.463656716417911 0.888775031711406 0.941237446777704 GO:0098960 postsynaptic neurotransmitter receptor activity 1/600 69/18639 0.0144927536231884 0.450217391304348 0.895845753898765 0.947628745453607 GO:0016782 transferase activity, transferring sulphur-containing groups 1/600 70/18639 0.0142857142857143 0.443785714285714 0.899210996099128 0.95009014022021 GO:0140299 molecular sensor activity 1/600 71/18639 0.0140845070422535 0.437535211267606 0.902467682099479 0.952431290797028 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/600 122/18639 0.0163934426229508 0.509262295081967 0.907331802152137 0.956461519549776 GO:0031491 nucleosome binding 1/600 74/18639 0.0135135135135135 0.419797297297297 0.911620805986281 0.959876913092575 GO:0019003 GDP binding 1/600 75/18639 0.0133333333333333 0.4142 0.914477122517831 0.961777663337719 GO:0017022 myosin binding 1/600 76/18639 0.0131578947368421 0.40875 0.917241274989783 0.962472209421618 GO:0051536 iron-sulfur cluster binding 1/600 76/18639 0.0131578947368421 0.40875 0.917241274989783 0.962472209421618 GO:0051540 metal cluster binding 1/600 77/18639 0.012987012987013 0.403441558441558 0.919916232432337 0.964173370762415 GO:0015370 solute:sodium symporter activity 1/600 79/18639 0.0126582278481013 0.393227848101266 0.925009963959413 0.966770062394394 GO:0016835 carbon-oxygen lyase activity 1/600 79/18639 0.0126582278481013 0.393227848101266 0.925009963959413 0.966770062394394 GO:0004252 serine-type endopeptidase activity 3/600 176/18639 0.0170454545454545 0.529517045454545 0.925563469571027 0.966770062394394 GO:0005262 calcium channel activity 2/600 131/18639 0.0152671755725191 0.474274809160305 0.926997745859321 0.967164124813317 GO:0099094 ligand-gated monoatomic cation channel activity 2/600 136/18639 0.0147058823529412 0.456838235294118 0.936150077763179 0.974723342327528 GO:0051117 ATPase binding 1/600 84/18639 0.0119047619047619 0.369821428571429 0.936373571481855 0.974723342327528 GO:0140767 enzyme-substrate adaptor activity 2/600 139/18639 0.0143884892086331 0.446978417266187 0.941108180707206 0.978538619712606 GO:0046943 carboxylic acid transmembrane transporter activity 3/600 188/18639 0.0159574468085106 0.495718085106383 0.943973107036293 0.980403397205685 GO:0005342 organic acid transmembrane transporter activity 3/600 189/18639 0.0158730158730159 0.493095238095238 0.945299297981842 0.980667639062795 GO:0022843 voltage-gated monoatomic cation channel activity 2/600 143/18639 0.013986013986014 0.434475524475524 0.947152436001645 0.98147732609457 GO:0008194 UDP-glycosyltransferase activity 2/600 145/18639 0.0137931034482759 0.42848275862069 0.949948439176092 0.982898522296528 GO:0008236 serine-type peptidase activity 3/600 194/18639 0.0154639175257732 0.480386597938144 0.951503684412229 0.982898522296528 GO:0015085 calcium ion transmembrane transporter activity 2/600 147/18639 0.0136054421768707 0.42265306122449 0.952603040703629 0.982898522296528 GO:0016410 N-acyltransferase activity 1/600 94/18639 0.0106382978723404 0.330478723404255 0.954201964969412 0.982898522296528 GO:0016758 hexosyltransferase activity 3/600 197/18639 0.0152284263959391 0.473071065989848 0.954904770838815 0.982898522296528 GO:0017171 serine hydrolase activity 3/600 198/18639 0.0151515151515152 0.470681818181818 0.95598803422583 0.982898522296528 GO:0019842 vitamin binding 2/600 150/18639 0.0133333333333333 0.4142 0.956334301032821 0.982898522296528 GO:0016407 acetyltransferase activity 1/600 96/18639 0.0104166666666667 0.32359375 0.957117577449405 0.982898522296528 GO:0030594 neurotransmitter receptor activity 1/600 97/18639 0.0103092783505155 0.320257731958763 0.958505133590826 0.983219952057854 GO:0003774 cytoskeletal motor activity 2/600 153/18639 0.0130718954248366 0.406078431372549 0.95978363846321 0.983428924069247 GO:0005261 monoatomic cation channel activity 6/600 341/18639 0.0175953079178886 0.546598240469208 0.965332126159835 0.987523356774699 GO:0005253 monoatomic anion channel activity 1/600 103/18639 0.00970873786407767 0.301601941747573 0.965938146790553 0.987523356774699 GO:0015081 sodium ion transmembrane transporter activity 2/600 164/18639 0.0121951219512195 0.378841463414634 0.970328837975843 0.990905007531135 GO:0008514 organic anion transmembrane transporter activity 4/600 269/18639 0.0148698884758364 0.461933085501859 0.97547293920987 0.993866900646596 GO:0005244 voltage-gated monoatomic ion channel activity 2/600 173/18639 0.0115606936416185 0.359132947976879 0.976923922119969 0.993866900646596 GO:0015294 solute:monoatomic cation symporter activity 1/600 116/18639 0.00862068965517241 0.267801724137931 0.977795981610827 0.993866900646596 GO:0022832 voltage-gated channel activity 2/600 175/18639 0.0114285714285714 0.355028571428571 0.978184046198456 0.993866900646596 GO:0046873 metal ion transmembrane transporter activity 8/600 450/18639 0.0177777777777778 0.552266666666667 0.978660193970036 0.993866900646596 GO:0015291 secondary active transmembrane transporter activity 4/600 287/18639 0.0139372822299652 0.432961672473868 0.983930216816578 0.996876391875526 GO:0015276 ligand-gated monoatomic ion channel activity 2/600 186/18639 0.010752688172043 0.334032258064516 0.984009294612264 0.996876391875526 GO:0022834 ligand-gated channel activity 2/600 188/18639 0.0106382978723404 0.330478723404255 0.98489208552511 0.996876391875526 GO:0140101 catalytic activity, acting on a tRNA 1/600 139/18639 0.00719424460431655 0.223489208633094 0.989593168308701 0.999767213290984 GO:0045182 translation regulator activity 5/600 356/18639 0.0140449438202247 0.436306179775281 0.990351597856129 0.999767213290984 GO:0015293 symporter activity 1/600 146/18639 0.00684931506849315 0.21277397260274 0.991738267668293 0.999767213290984 GO:0008509 monoatomic anion transmembrane transporter activity 1/600 149/18639 0.00671140939597315 0.208489932885906 0.992516648680108 0.999767213290984 GO:0015103 inorganic anion transmembrane transporter activity 1/600 165/18639 0.00606060606060606 0.188272727272727 0.995586568186047 0.999767213290984 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/600 167/18639 0.00598802395209581 0.186017964071856 0.995868599852219 0.999767213290984 GO:0005216 monoatomic ion channel activity 6/600 448/18639 0.0133928571428571 0.416049107142857 0.99655161043075 0.999767213290984 GO:0022836 gated channel activity 3/600 318/18639 0.00943396226415094 0.293066037735849 0.998080145254861 0.999767213290984 GO:0008168 methyltransferase activity 1/600 204/18639 0.00490196078431373 0.152279411764706 0.99878391872616 0.999767213290984 GO:0016741 transferase activity, transferring one-carbon groups 1/600 215/18639 0.00465116279069767 0.144488372093023 0.999155015614594 0.999767213290984 GO:0030371 translation repressor activity 2/600 329/18639 0.0060790273556231 0.188844984802432 0.999767213290984 0.999767213290984