category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	8/34	238/9376	9.26940187839842	RPS18/RPL7A/RPS25/RPS9/RPL17/RPS17/PLCG2/IL6ST	7.79546750062477
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	5/34	95/9376	14.5139318885449	ATP6V0C/FLT1/CCL3/HLA-DRA/HLA-DRB1	7.98640458187807
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	5/34	100/9376	13.7882352941176	CCL4/CCL3/CCL4L2/TNFSF10/IL6ST	7.75595737510481
Genetic Information Processing	Translation	hsa03010	Ribosome	6/34	222/9376	7.45310015898251	RPS18/RPL7A/RPS25/RPS9/RPL17/RPS17	5.87008789700588
Human Diseases	Immune disease	hsa05310	Asthma	3/34	32/9376	25.8529411764706	PRG2/HLA-DRA/HLA-DRB1	8.4955506100493
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	4/34	82/9376	13.4519368723099	HLA-DRA/CTSB/HLA-G/HLA-DRB1	6.83199701034121
Human Diseases	Immune disease	hsa05330	Allograft rejection	3/34	39/9376	21.2126696832579	HLA-DRA/HLA-G/HLA-DRB1	7.63057856330597
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	3/34	44/9376	18.8021390374332	HLA-DRA/HLA-G/HLA-DRB1	7.14029782956144
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	3/34	45/9376	18.3843137254902	HLA-DRA/HLA-G/HLA-DRB1	7.05187942957012
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	4/34	109/9376	10.1198057204533	SPP1/CCL4/CCL3/CCL4L2	5.77742636986372
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	6/34	298/9376	5.55230951440979	CCL4/CCL3/CCL4L2/TNFSF10/CSH1/IL6ST	4.81781356877293
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	3/34	54/9376	15.3202614379085	HLA-DRA/HLA-G/HLA-DRB1	6.36646627154271
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	3/34	70/9376	11.818487394958	HLA-DRA/HLA-G/HLA-DRB1	5.48074005582715
NA	NA	hsa04518	Integrin signaling	4/34	154/9376	7.16271963330787	SPP1/FN1/FLT1/COL4A1	4.65184651626064
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	4/34	155/9376	7.11650853889943	ATP6V0C/HLA-DRA/HLA-G/HLA-DRB1	4.63218173389191
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	3/34	89/9376	9.29543952412426	SPP1/FN1/COL4A1	4.74353213824978
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	4/34	193/9376	5.71533069186224	CCL4/CCL3/CCL4L2/PLCG2	3.9930402077915
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	3/34	101/9376	8.19103086779266	FN1/PLCG2/COL4A1	4.38328839823304
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	4/34	203/9376	5.43378730802666	SPP1/FN1/FLT1/COL4A1	3.85276343284005
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	4/34	205/9376	5.38077474892396	HLA-DRA/HLA-G/PLCG2/HLA-DRB1	3.825821224878
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	3/34	105/9376	7.87899159663866	CCL4/CCL4L2/PLCG2	4.27623243366602
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	5/34	333/9376	4.14061119943473	ATP6V0C/SPP1/FN1/HLA-G/COL4A1	3.52034471177321
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	3/34	109/9376	7.58985429033999	HLA-DRA/HLA-DRB1/IL6ST	4.17469397019977
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	2/34	37/9376	14.906200317965	HBA2/HBA1	5.11286493976779
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	4/34	227/9376	4.85928997149521	CCL4/CCL3/CCL4L2/HLA-G	3.5509020363086
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	5/34	362/9376	3.80890477738057	SPP1/FN1/FLT1/CSH1/COL4A1	3.28804452876689
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	3/34	133/9376	6.2202565236621	HLA-G/PLCG2/TNFSF10	3.65776966612794
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	2/34	50/9376	11.0305882352941	AOC1/SMOX	4.29011431340855
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	2/34	50/9376	11.0305882352941	HLA-DRA/HLA-DRB1	4.29011431340855
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	2/34	50/9376	11.0305882352941	HBA2/HBA1	4.29011431340855
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	2/34	51/9376	10.8143021914648	ATP6V0C/PLCG2	4.23960366810591
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	3/34	160/9376	5.17058823529412	HLA-DRA/HLA-G/HLA-DRB1	3.20989803816945
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	2/34	66/9376	8.35650623885918	HLA-DRA/HLA-DRB1	3.61804446669008
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	3/34	173/9376	4.78204692281537	HLA-DRA/HLA-DRB1/TNFSF10	3.0289382424054
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	3/34	180/9376	4.59607843137255	HLA-DRA/HLA-G/HLA-DRB1	2.93880717665823
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/34	71/9376	7.76801988400994	ATP6V0C/PLCG2	3.45332757752917
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	3/34	181/9376	4.57068573285668	ATP6V0C/HLA-DRA/HLA-DRB1	2.92630920994916
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	2/34	78/9376	7.07088989441931	HLA-DRA/HLA-DRB1	3.24795536233876
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	3/34	196/9376	4.22088835534214	HLA-G/PLCG2/IL6ST	2.74908097045843
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	2/34	83/9376	6.64493267186393	CCL4/CCL4L2	3.11619774700756
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/34	93/9376	5.93042378241619	HLA-DRA/HLA-DRB1	2.88261547582319
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	2/34	93/9376	5.93042378241619	FN1/COL4A1	2.88261547582319
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	3/34	224/9376	3.69327731092437	HLA-DRA/HLA-G/HLA-DRB1	2.46123023277665
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/34	99/9376	5.57100415923945	HLA-DRA/HLA-DRB1	2.75823078071024
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/34	100/9376	5.51529411764706	HLA-DRA/HLA-DRB1	2.73848798580058
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/34	103/9376	5.35465448315248	FN1/COL4A1	2.68081811599577
Metabolism	Amino acid metabolism	hsa00360	Phenylalanine metabolism	1/34	16/9376	17.2352941176471	MIF	3.92091468754024
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	2/34	110/9376	5.01390374331551	FLT1/PLCG2	2.55459650358285
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	2/34	112/9376	4.92436974789916	HLA-DRA/HLA-DRB1	2.52048909370501
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/34	122/9376	4.52073288331726	PLCG2/CSH1	2.36131219241807
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/34	22/9376	12.5347593582888	AOC1	3.26758099498001
Genetic Information Processing	Replication and repair	hsa03430	Mismatch repair	1/34	23/9376	11.9897698209719	POLD4	3.18333403337629
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	2/34	133/9376	4.1468376824414	GABARAP/TNFSF10	2.20495053583837
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	2/34	137/9376	4.02576212966939	CTSB/TNFSF10	2.15222537874907
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/34	143/9376	3.85684903331962	HLA-DRA/HLA-DRB1	2.07677313631858
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	1/34	28/9376	9.84873949579832	ATP6V0C	2.82882602512454
Metabolism	Metabolism of other amino acids	hsa00410	beta-Alanine metabolism	1/34	31/9376	8.89563567362429	SMOX	2.65633876338408
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	1/34	32/9376	8.61764705882353	GABARAP	2.60396166627547
Genetic Information Processing	Replication and repair	hsa03030	DNA replication	1/34	36/9376	7.66013071895425	POLD4	2.41527024284522
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/34	168/9376	3.28291316526611	CSH1/IL6ST	1.80121909950925
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/34	169/9376	3.26348764357814	GABARAP/CTSB	1.79129689866215
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/34	37/9376	7.45310015898251	MIF	2.3725984669621
Genetic Information Processing	Replication and repair	hsa03440	Homologous recombination	1/34	41/9376	6.72596843615495	POLD4	2.21660792766057
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/34	42/9376	6.56582633053221	AOC1	2.1808488327918
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/34	187/9376	2.94935514312677	GABARAP/CTSB	1.62436196202409
Genetic Information Processing	Replication and repair	hsa03410	Base excision repair	1/34	44/9376	6.26737967914439	POLD4	2.11270452451728
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	2/34	204/9376	2.70357554786621	FN1/PLCG2	1.48405372642519
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	2/34	205/9376	2.69038737446198	HLA-G/IL6ST	1.47625026762012
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/34	214/9376	2.57724024189115	HLA-G/PLCG2	1.40803923758028
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	2/34	216/9376	2.55337690631808	CCL3/TNFSF10	1.39335297207251
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/34	56/9376	4.92436974789916	EEF1G	1.77689244874649
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/34	60/9376	4.59607843137255	PLCG2	1.68575790832827
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/34	63/9376	4.37721755368814	POLD4	1.62251857130544
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	2/34	233/9376	2.36707902044938	FN1/COL4A1	1.27477161453454
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/34	65/9376	4.24253393665158	SPP1	1.58251636711751
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	2/34	238/9376	2.3173504695996	FLT1/PLCG2	1.24185073161367
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/34	69/9376	3.99658994032396	PLCG2	1.50713505336824
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/34	69/9376	3.99658994032396	CTSB	1.50713505336824
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/34	250/9376	2.20611764705882	ATP6V0C/CTSB	1.16606996496861
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/34	73/9376	3.77759871071716	PLCG2	1.43722441671385
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/34	254/9376	2.17137563686892	FLT1/PLCG2	1.14175566896494
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/34	76/9376	3.62848297213622	PLCG2	1.38795586059867
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/34	78/9376	3.53544494720965	PLCG2	1.35647527058173
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/34	78/9376	3.53544494720965	FN1	1.35647527058173
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/34	79/9376	3.49069247952345	ATP6V0C	1.3411192764478
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/34	80/9376	3.44705882352941	PLCG2	1.32600911818388
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/34	86/9376	3.20656634746922	PLCG2	1.24011946509473
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/34	88/9376	3.13368983957219	SERPINE2	1.21315610230424
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/34	89/9376	3.09847984137475	GABARAP	1.19996132092606
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/34	91/9376	3.03038138332256	PLCG2	1.17412011940079
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/34	98/9376	2.81392557022809	PLCG2	1.08895637556743
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/34	98/9376	2.81392557022809	PLCG2	1.08895637556743
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/34	99/9376	2.78550207961973	PLCG2	1.07740588795454
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/34	103/9376	2.67732724157624	COL4A1	1.03259840087601
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/34	103/9376	2.67732724157624	CCL3	1.03259840087601
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/34	105/9376	2.62633053221289	GABARAP	1.01098646102553
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/34	105/9376	2.62633053221289	PLCG2	1.01098646102553
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/34	116/9376	2.37728194726166	PLCG2	0.900433245538203
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/34	120/9376	2.29803921568627	PLCG2	0.863320251623828
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/34	122/9376	2.26036644165863	PLCG2	0.845312252941774
Organismal Systems	Immune system	hsa04611	Platelet activation	1/34	126/9376	2.18860877684407	PLCG2	0.810323631159112
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/34	130/9376	2.12126696832579	COL4A1	0.77662063415708
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	1/34	138/9376	1.99829497016198	ATP6V0C	0.712712888368271
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/34	138/9376	1.99829497016198	FN1	0.712712888368271
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/34	140/9376	1.96974789915966	SPP1	0.697406624610962
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/34	142/9376	1.94200497100249	PLCG2	0.682350630092204
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/34	144/9376	1.91503267973856	IL6ST	0.66753665512353
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/34	149/9376	1.8507698381366	PLCG2	0.631509842703638
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/34	157/9376	1.75646309479206	HLA-G	0.576634774155491
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/34	158/9376	1.74534623976173	CDKN1C	0.569998117871738
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/34	168/9376	1.64145658263305	TNFSF10	0.50610941569033
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/34	170/9376	1.62214532871972	PLCG2	0.493839683129879
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/34	178/9376	1.54923992068738	NOTUM	0.446303774244058
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/34	184/9376	1.49872122762148	PLCG2	0.412161026412039
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/34	195/9376	1.41417797888386	PLCG2	0.352585527326782
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/34	200/9376	1.37882352941176	TNFSF10	0.326685912183308
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/34	201/9376	1.37196371085748	FLT1	0.321588662357798
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/34	212/9376	1.3007769145394	FLT1	0.267223750683066
NA	NA	hsa04382	Cornified envelope formation	1/34	217/9376	1.27080509623204	COL4A1	0.243482546734595
NA	NA	hsa04081	Hormone signaling	1/34	219/9376	1.25919957023905	CSH1	0.234145002442275
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	1/34	232/9376	1.18864097363083	FN1	0.175516147704387
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/34	248/9376	1.11195445920304	TNFSF10	0.107791517592652
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/34	250/9376	1.10305882352941	HLA-G	0.0996368795661827
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	1/34	253/9376	1.08997907463381	PLCG2	0.0875262074835216
NA	NA	hsa04517	IgSF CAM signaling	1/34	299/9376	0.922289986228605	PLCG2	-0.0823847024716698
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	1/34	300/9376	0.91921568627451	FLT1	-0.0857917622827332
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/34	323/9376	0.85376069932617	PLCG2	-0.16135196835648
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/34	370/9376	0.745310015898251	CSH1	-0.301544854576744