ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0004674 protein serine/threonine kinase activity 144/3513 433/18639 0.33256351039261 1.76448940227949 3.90459579557692e-13 4.01559771525186e-10 GO:0003712 transcription coregulator activity 159/3513 495/18639 0.321212121212121 1.70426209145253 6.02038637968795e-13 4.01559771525186e-10 GO:0045296 cadherin binding 116/3513 334/18639 0.347305389221557 1.84270570728739 3.26103259316319e-12 1.45007249309323e-09 GO:0030695 GTPase regulator activity 153/3513 489/18639 0.312883435582822 1.66007240416403 1.60228526122472e-11 5.07974883353241e-09 GO:0060589 nucleoside-triphosphatase regulator activity 153/3513 490/18639 0.312244897959184 1.65668450129838 1.90395383565683e-11 5.07974883353241e-09 GO:0106310 protein serine kinase activity 117/3513 361/18639 0.32409972299169 1.71958290260236 3.7845820172627e-10 8.41438735171407e-08 GO:0003713 transcription coactivator activity 89/3513 256/18639 0.34765625 1.84456727690009 1.00520797394874e-09 1.91563919606802e-07 GO:0005085 guanyl-nucleotide exchange factor activity 81/3513 230/18639 0.352173913043478 1.86853673931608 2.83257780671255e-09 4.72332349269318e-07 GO:0031267 small GTPase binding 94/3513 283/18639 0.332155477031802 1.7623244908613 5.01410554093341e-09 7.43201865733907e-07 GO:0004679 AMP-activated protein kinase activity 84/3513 248/18639 0.338709677419355 1.79709925346409 1.17841923915505e-08 1.29502995634389e-06 GO:0035173 histone kinase activity 112/3513 360/18639 0.311111111111111 1.65066894392257 1.19208015149998e-08 1.29502995634389e-06 GO:0140996 histone H3 kinase activity 111/3513 357/18639 0.310924369747899 1.64967814623715 1.43494566423429e-08 1.29502995634389e-06 GO:0141003 histone H2AX kinase activity 110/3513 354/18639 0.310734463276836 1.64867055537061 1.72715443786344e-08 1.29502995634389e-06 GO:0004677 DNA-dependent protein kinase activity 83/3513 246/18639 0.33739837398374 1.79014184249443 1.75453959341474e-08 1.29502995634389e-06 GO:0140857 histone H3T45 kinase activity 83/3513 246/18639 0.33739837398374 1.79014184249443 1.75453959341474e-08 1.29502995634389e-06 GO:0035402 histone H3T11 kinase activity 83/3513 247/18639 0.336032388663968 1.78289430467056 2.15999687116603e-08 1.29502995634389e-06 GO:0004676 3-phosphoinositide-dependent protein kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0004711 ribosomal protein S6 kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0035175 histone H3S10 kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0035979 histone H2AXS139 kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0044022 histone H3S28 kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0044023 histone H4S1 kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0044024 histone H2AS1 kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0044025 histone H2BS14 kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0072354 histone H3T3 kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0072371 histone H2AS121 kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0072518 Rho-dependent protein serine/threonine kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0140823 histone H2BS36 kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0140855 histone H3S57 kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0140995 histone H2A kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0140997 histone H4 kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0140998 histone H2B kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:1990244 histone H2AT120 kinase activity 82/3513 245/18639 0.33469387755102 1.77579253733944 3.20359734327949e-08 1.29502995634389e-06 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 81/3513 243/18639 0.333333333333333 1.76857386848847 4.74212039334053e-08 1.78119864462166e-06 GO:0051020 GTPase binding 99/3513 315/18639 0.314285714285714 1.66751250457484 4.74397455074241e-08 1.78119864462166e-06 GO:0035403 histone H3T6 kinase activity 82/3513 247/18639 0.331983805668016 1.76141365039743 4.80683292401647e-08 1.78119864462166e-06 GO:0004842 ubiquitin-protein transferase activity 130/3513 449/18639 0.289532293986637 1.53617774768486 9.9369369724466e-08 3.58266862736318e-06 GO:0019787 ubiquitin-like protein transferase activity 134/3513 479/18639 0.279749478079332 1.48427284996318 5.41163964419198e-07 1.89977033825055e-05 GO:0140297 DNA-binding transcription factor binding 136/3513 488/18639 0.278688524590164 1.47864372611331 5.62351846398814e-07 1.9235317002462e-05 GO:0016755 aminoacyltransferase activity 137/3513 496/18639 0.276209677419355 1.4654916531225 8.78525678062876e-07 2.92988313633969e-05 GO:0038024 cargo receptor activity 29/3513 65/18639 0.446153846153846 2.36716810089995 1.71395419897583e-06 5.57662171081405e-05 GO:0035091 phosphatidylinositol binding 86/3513 284/18639 0.302816901408451 1.60666217630291 1.98269495667597e-06 6.29741683858512e-05 GO:0061630 ubiquitin protein ligase activity 102/3513 353/18639 0.288951841359773 1.53309802764156 2.53908002324315e-06 7.87705290931713e-05 GO:0005096 GTPase activator activity 82/3513 271/18639 0.302583025830258 1.6054212975947 3.50915439532702e-06 0.000106391180985596 GO:0061659 ubiquitin-like protein ligase activity 105/3513 372/18639 0.282258064516129 1.49758271122008 5.77676230046736e-06 0.000171248909084966 GO:1901981 phosphatidylinositol phosphate binding 60/3513 185/18639 0.324324324324324 1.72077457474554 6.64386863111066e-06 0.000191726946228436 GO:0004559 alpha-mannosidase activity 11/3513 15/18639 0.733333333333333 3.89086251067464 6.75499735587444e-06 0.000191726946228436 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 99/3513 349/18639 0.283667621776504 1.50506142963059 8.39677048116133e-06 0.000233360246288942 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 26/3513 60/18639 0.433333333333333 2.29914602903501 1.11482017249218e-05 0.000299817440964857 GO:0003714 transcription corepressor activity 64/3513 204/18639 0.313725490196078 1.66454011151856 1.12375352685479e-05 0.000299817440964857 GO:0015923 mannosidase activity 11/3513 16/18639 0.6875 3.64768360375747 1.79127630188648e-05 0.000468541683669915 GO:0015924 mannosyl-oligosaccharide mannosidase activity 8/3513 10/18639 0.8 4.24457728437233 4.93987798033801e-05 0.00126726869726363 GO:0019838 growth factor binding 45/3513 136/18639 0.330882352941176 1.75556964886723 5.21302342338234e-05 0.00131210815977208 GO:0008013 beta-catenin binding 37/3513 106/18639 0.349056603773585 1.85199716417189 6.62620515242795e-05 0.00163691808765535 GO:0005543 phospholipid binding 128/3513 497/18639 0.257545271629779 1.36646351207158 7.48248734323289e-05 0.00181484329379503 GO:0004402 histone acetyltransferase activity 19/3513 42/18639 0.452380952380952 2.40020739294864 8.22731916948737e-05 0.00195986495930289 GO:0034212 protein N-acetyltransferase activity 22/3513 53/18639 0.415094339622642 2.20237500604225 0.000113687672953272 0.00266069045122218 GO:0003779 actin binding 115/3513 443/18639 0.259593679458239 1.37733179374384 0.000120100595510793 0.00276231369674825 GO:0061733 protein-lysine-acetyltransferase activity 20/3513 47/18639 0.425531914893617 2.25775387466613 0.000153145719959447 0.00346265068518478 GO:0000149 SNARE binding 36/3513 106/18639 0.339622641509434 1.80194318676184 0.000155999378974764 0.00346838619253893 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 32/3513 91/18639 0.351648351648352 1.86574825686696 0.000171134217560425 0.00374250895451814 GO:0017124 SH3 domain binding 38/3513 115/18639 0.330434782608696 1.75319496528422 0.000198404991768757 0.00423540327880686 GO:0016758 hexosyltransferase activity 58/3513 197/18639 0.294416243654822 1.56209062495936 0.000200022793526861 0.00423540327880686 GO:0046030 inositol trisphosphate phosphatase activity 9/3513 14/18639 0.642857142857143 3.41082103208491 0.000236737582080838 0.00484108189414514 GO:0140030 modification-dependent protein binding 52/3513 173/18639 0.300578034682081 1.59478337274105 0.000238542687769238 0.00484108189414514 GO:0016757 glycosyltransferase activity 74/3513 267/18639 0.277153558052434 1.47049962099041 0.000239513796861754 0.00484108189414514 GO:0016922 nuclear receptor binding 43/3513 137/18639 0.313868613138686 1.66529948200739 0.00028582448671719 0.00569089351165271 GO:0005160 transforming growth factor beta receptor binding 13/3513 26/18639 0.5 2.65286080273271 0.000325909418925576 0.00630091543256113 GO:0070412 R-SMAD binding 13/3513 26/18639 0.5 2.65286080273271 0.000325909418925576 0.00630091543256113 GO:1990841 promoter-specific chromatin binding 25/3513 68/18639 0.367647058823529 1.95063294318581 0.000393311938283395 0.00749540179528642 GO:0019902 phosphatase binding 55/3513 190/18639 0.289473684210526 1.53586678052946 0.000457128131040453 0.00858885812405584 GO:0019903 protein phosphatase binding 44/3513 144/18639 0.305555555555556 1.6211927127811 0.000468996699157952 0.00868946662050984 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 64/3513 229/18639 0.279475982532751 1.48282175873269 0.000476452056574106 0.00870667182835421 GO:0005385 zinc ion transmembrane transporter activity 13/3513 27/18639 0.481481481481481 2.55460669892779 0.000520593800062013 0.00938475850382061 GO:0140033 acetylation-dependent protein binding 12/3513 24/18639 0.5 2.65286080273271 0.00055374784380804 0.00984932831519901 GO:0001223 transcription coactivator binding 18/3513 44/18639 0.409090909090909 2.17052247496312 0.000577044926976494 0.010128657007719 GO:0004445 inositol-polyphosphate 5-phosphatase activity 7/3513 10/18639 0.7 3.71400512382579 0.000589206789915518 0.0102078163343805 GO:0032266 phosphatidylinositol-3-phosphate binding 19/3513 48/18639 0.395833333333333 2.10018146883006 0.000668579238696813 0.0114344192874557 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 13/3513 28/18639 0.464285714285714 2.46337074539466 0.000805126717637821 0.0135954309028969 GO:0051011 microtubule minus-end binding 8/3513 13/18639 0.615384615384615 3.26505944951718 0.000819723348269111 0.0136688868323874 GO:1902936 phosphatidylinositol bisphosphate binding 35/3513 111/18639 0.315315315315315 1.67297528100261 0.000915155398743273 0.0149622528164034 GO:0010485 histone H4 acetyltransferase activity 15/3513 35/18639 0.428571428571429 2.27388068805661 0.000919718688864375 0.0149622528164034 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 9/3513 16/18639 0.5625 2.9844684030743 0.000938076625285493 0.0150770387726608 GO:0016407 acetyltransferase activity 31/3513 96/18639 0.322916666666667 1.71330593509821 0.00113211455445682 0.0179790573291119 GO:0010484 histone H3 acetyltransferase activity 13/3513 29/18639 0.448275862068966 2.37842692658794 0.00120941770713887 0.0189807437802736 GO:0008080 N-acetyltransferase activity 24/3513 69/18639 0.347826086956522 1.84546838450971 0.00126547204197871 0.0196295314418558 GO:0004712 protein serine/threonine/tyrosine kinase activity 17/3513 43/18639 0.395348837209302 2.09761086727702 0.00128512057205809 0.0197051821048907 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 7/3513 11/18639 0.636363636363636 3.37636829438708 0.00135608391373431 0.0201722326801098 GO:0005114 type II transforming growth factor beta receptor binding 7/3513 11/18639 0.636363636363636 3.37636829438708 0.00135608391373431 0.0201722326801098 GO:0052742 phosphatidylinositol kinase activity 12/3513 26/18639 0.461538461538462 2.44879458713788 0.00136094523329076 0.0201722326801098 GO:0070577 lysine-acetylated histone binding 11/3513 23/18639 0.478260869565217 2.53751902870085 0.00150242695766468 0.0220245885881834 GO:0030331 nuclear estrogen receptor binding 16/3513 40/18639 0.4 2.12228864218617 0.00152984498093647 0.0221827522235789 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 8/3513 14/18639 0.571428571428571 3.03184091740881 0.00159703770318681 0.0226552044451681 GO:0031418 L-ascorbic acid binding 10/3513 20/18639 0.5 2.65286080273271 0.00161337662840403 0.0226552044451681 GO:0052745 inositol phosphate phosphatase activity 10/3513 20/18639 0.5 2.65286080273271 0.00161337662840403 0.0226552044451681 GO:0043995 histone H4K5 acetyltransferase activity 13/3513 30/18639 0.433333333333333 2.29914602903501 0.00176938315484081 0.0240426397922279 GO:0043996 histone H4K8 acetyltransferase activity 13/3513 30/18639 0.433333333333333 2.29914602903501 0.00176938315484081 0.0240426397922279 GO:0043997 histone H4K12 acetyltransferase activity 13/3513 30/18639 0.433333333333333 2.29914602903501 0.00176938315484081 0.0240426397922279 GO:0004713 protein tyrosine kinase activity 41/3513 140/18639 0.292857142857143 1.55381847017201 0.0017842738676391 0.0240426397922279 GO:0001221 transcription coregulator binding 35/3513 115/18639 0.304347826086957 1.614784836446 0.00182340237154897 0.0243241876364633 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 12/3513 27/18639 0.444444444444444 2.35809849131796 0.00203322637987375 0.0268546929777385 GO:0052866 phosphatidylinositol phosphate phosphatase activity 14/3513 34/18639 0.411764705882353 2.18470889636811 0.00214748635960514 0.0280857529775809 GO:0035591 signaling adaptor activity 38/3513 129/18639 0.294573643410853 1.56292574424563 0.00229209073219019 0.0290223869999417 GO:0043998 histone H2A acetyltransferase activity 11/3513 24/18639 0.458333333333333 2.43178906917165 0.00230515543862031 0.0290223869999417 GO:0070300 phosphatidic acid binding 11/3513 24/18639 0.458333333333333 2.43178906917165 0.00230515543862031 0.0290223869999417 GO:0042393 histone binding 65/3513 247/18639 0.263157894736842 1.39624252775406 0.0023061267031438 0.0290223869999417 GO:0004620 phospholipase activity 33/3513 109/18639 0.302752293577982 1.60631938514091 0.00265928597776781 0.0328677855829123 GO:0016298 lipase activity 38/3513 130/18639 0.292307692307692 1.55090323852066 0.00266096015213983 0.0328677855829123 GO:0031543 peptidyl-proline dioxygenase activity 7/3513 12/18639 0.583333333333333 3.09500426985483 0.00272567672595533 0.03305502502204 GO:0097677 STAT family protein binding 7/3513 12/18639 0.583333333333333 3.09500426985483 0.00272567672595533 0.03305502502204 GO:0051213 dioxygenase activity 29/3513 93/18639 0.311827956989247 1.65447232858599 0.00289662628942482 0.0348117069377721 GO:0036408 histone H3K14 acetyltransferase activity 12/3513 28/18639 0.428571428571429 2.27388068805661 0.00295430112655071 0.0348764398479527 GO:0046966 nuclear thyroid hormone receptor binding 12/3513 28/18639 0.428571428571429 2.27388068805661 0.00295430112655071 0.0348764398479527 GO:0008483 transaminase activity 11/3513 25/18639 0.44 2.33451750640478 0.00342237754362157 0.0392538159616769 GO:0043425 bHLH transcription factor binding 13/3513 32/18639 0.40625 2.15544940222032 0.00353090627219351 0.0392538159616769 GO:0048156 tau protein binding 16/3513 43/18639 0.372093023255814 1.97422199273132 0.00365588672962101 0.0392538159616769 GO:0048029 monosaccharide binding 24/3513 74/18639 0.324324324324324 1.72077457474554 0.00365820895887341 0.0392538159616769 GO:0140359 ABC-type transporter activity 17/3513 47/18639 0.361702127659574 1.91909079346621 0.00390895299950124 0.0392538159616769 GO:0140938 histone H3 methyltransferase activity 17/3513 47/18639 0.361702127659574 1.91909079346621 0.00390895299950124 0.0392538159616769 GO:0032931 histone H3K56 acetyltransferase activity 10/3513 22/18639 0.454545454545455 2.41169163884792 0.00391361133650902 0.0392538159616769 GO:0043992 histone H3K9 acetyltransferase activity 10/3513 22/18639 0.454545454545455 2.41169163884792 0.00391361133650902 0.0392538159616769 GO:0043993 histone H3K18 acetyltransferase activity 10/3513 22/18639 0.454545454545455 2.41169163884792 0.00391361133650902 0.0392538159616769 GO:0043994 histone H3K23 acetyltransferase activity 10/3513 22/18639 0.454545454545455 2.41169163884792 0.00391361133650902 0.0392538159616769 GO:0043999 histone H2AK5 acetyltransferase activity 10/3513 22/18639 0.454545454545455 2.41169163884792 0.00391361133650902 0.0392538159616769 GO:0044012 histone H2AK9 acetyltransferase activity 10/3513 22/18639 0.454545454545455 2.41169163884792 0.00391361133650902 0.0392538159616769 GO:0044014 histone H2BK5 acetyltransferase activity 10/3513 22/18639 0.454545454545455 2.41169163884792 0.00391361133650902 0.0392538159616769 GO:0044015 histone H2BK12 acetyltransferase activity 10/3513 22/18639 0.454545454545455 2.41169163884792 0.00391361133650902 0.0392538159616769 GO:0044016 histone H3K4 acetyltransferase activity 10/3513 22/18639 0.454545454545455 2.41169163884792 0.00391361133650902 0.0392538159616769 GO:0044017 histone H3K27 acetyltransferase activity 10/3513 22/18639 0.454545454545455 2.41169163884792 0.00391361133650902 0.0392538159616769 GO:0044018 histone H3K36 acetyltransferase activity 10/3513 22/18639 0.454545454545455 2.41169163884792 0.00391361133650902 0.0392538159616769 GO:0046972 histone H4K16 acetyltransferase activity 10/3513 22/18639 0.454545454545455 2.41169163884792 0.00391361133650902 0.0392538159616769 GO:0050321 tau-protein kinase activity 10/3513 22/18639 0.454545454545455 2.41169163884792 0.00391361133650902 0.0392538159616769 GO:0140908 histone H3K122 acetyltransferase activity 10/3513 22/18639 0.454545454545455 2.41169163884792 0.00391361133650902 0.0392538159616769 GO:0016409 palmitoyltransferase activity 14/3513 36/18639 0.388888888888889 2.06333617990322 0.00402326518812529 0.0400525056787995 GO:0008374 O-acyltransferase activity 19/3513 55/18639 0.345454545454545 1.83288564552442 0.00425407689161787 0.0420365820253203 GO:0046332 SMAD binding 25/3513 79/18639 0.316455696202532 1.67902582451437 0.00439443204650378 0.0431042084561474 GO:0042054 histone methyltransferase activity 22/3513 67/18639 0.328358208955224 1.74217724358566 0.00445397205434879 0.0433693337262867 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 6/3513 10/18639 0.6 3.18343296327925 0.00466281783628571 0.0444299928114653 GO:0008239 dipeptidyl-peptidase activity 6/3513 10/18639 0.6 3.18343296327925 0.00466281783628571 0.0444299928114653 GO:0016303 1-phosphatidylinositol-3-kinase activity 6/3513 10/18639 0.6 3.18343296327925 0.00466281783628571 0.0444299928114653 GO:0046974 histone H3K9 methyltransferase activity 7/3513 13/18639 0.538461538461538 2.85692701832753 0.00494928899992257 0.046825188126927 GO:0019207 kinase regulator activity 72/3513 287/18639 0.250871080139373 1.33105211008192 0.00510700328065452 0.047977058988684 GO:0016741 transferase activity, transferring one-carbon groups 56/3513 215/18639 0.26046511627907 1.38195539491192 0.00556855292260118 0.0519471999912585 GO:0044013 histone H2B acetyltransferase activity 10/3513 23/18639 0.434782608695652 2.30683548063714 0.00576836855100465 0.0526072470666063 GO:0001727 lipid kinase activity 15/3513 41/18639 0.365853658536585 1.94111766053613 0.00578867515791402 0.0526072470666063 GO:0016769 transferase activity, transferring nitrogenous groups 12/3513 30/18639 0.4 2.12228864218617 0.00579705046386141 0.0526072470666063 GO:0051721 protein phosphatase 2A binding 12/3513 30/18639 0.4 2.12228864218617 0.00579705046386141 0.0526072470666063 GO:0042826 histone deacetylase binding 36/3513 127/18639 0.283464566929134 1.5039840771398 0.00584878867290894 0.0527040625302285 GO:0042578 phosphoric ester hydrolase activity 88/3513 363/18639 0.242424242424242 1.28623554071889 0.00588673561994306 0.0527040625302285 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 27/3513 89/18639 0.303370786516854 1.60960093648951 0.00599397503460824 0.0529533953388569 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 27/3513 89/18639 0.303370786516854 1.60960093648951 0.00599397503460824 0.0529533953388569 GO:0046915 transition metal ion transmembrane transporter activity 16/3513 45/18639 0.355555555555556 1.88647879305437 0.00611090884647351 0.0536312657973399 GO:0001618 virus receptor activity 25/3513 81/18639 0.308641975308642 1.63756839674858 0.00628487659532445 0.0547975514912602 GO:0008194 UDP-glycosyltransferase activity 40/3513 145/18639 0.275862068965517 1.46364733943873 0.00634542333345314 0.0549661995248473 GO:0002039 p53 binding 22/3513 69/18639 0.318840579710145 1.69167935246723 0.00658570170552258 0.0566795230655944 GO:0019905 syntaxin binding 20/3513 61/18639 0.327868852459016 1.73958085425096 0.00663730309202619 0.0567574507997624 GO:0005044 scavenger receptor activity 11/3513 27/18639 0.407407407407407 2.16159028370813 0.00692844145273255 0.0588696872480587 GO:0043531 ADP binding 14/3513 38/18639 0.368421052631579 1.95473953885568 0.00704861390328514 0.0592078125318711 GO:0140793 histone H2AXY142 phosphatase activity 27/3513 90/18639 0.3 1.59171648163962 0.0070570031428542 0.0592078125318711 GO:0140272 exogenous protein binding 25/3513 82/18639 0.304878048780488 1.61759805044677 0.00745646481132912 0.0621682753644566 GO:0051015 actin filament binding 54/3513 209/18639 0.258373205741627 1.37085629997671 0.00758282694705013 0.0628291375612725 GO:0030276 clathrin binding 16/3513 46/18639 0.347826086956522 1.84546838450971 0.0077612218528729 0.0639103083440274 GO:0019887 protein kinase regulator activity 64/3513 255/18639 0.250980392156863 1.33163208921485 0.00783882377838063 0.0639528141704676 GO:0017147 Wnt-protein binding 12/3513 31/18639 0.387096774193548 2.05382771824468 0.00786226501046229 0.0639528141704676 GO:0008276 protein methyltransferase activity 28/3513 95/18639 0.294736842105263 1.56379163108454 0.00799611446606376 0.0646473739256306 GO:0032454 histone H3K9 demethylase activity 7/3513 14/18639 0.5 2.65286080273271 0.00830154029665834 0.0663129027289954 GO:0042813 Wnt receptor activity 7/3513 14/18639 0.5 2.65286080273271 0.00830154029665834 0.0663129027289954 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 6/3513 11/18639 0.545454545454545 2.8940299666175 0.00863089854334737 0.0681279210463041 GO:0048185 activin binding 6/3513 11/18639 0.545454545454545 2.8940299666175 0.00863089854334737 0.0681279210463041 GO:0016798 hydrolase activity, acting on glycosyl bonds 36/3513 130/18639 0.276923076923077 1.46927675228273 0.00868634806000253 0.0681622841884904 GO:0030295 protein kinase activator activity 38/3513 139/18639 0.273381294964029 1.45048504322076 0.00894518401960062 0.0694678076694975 GO:0043130 ubiquitin binding 29/3513 100/18639 0.29 1.53865926558497 0.00895686875498768 0.0694678076694975 GO:0030246 carbohydrate binding 69/3513 280/18639 0.246428571428571 1.30748139563255 0.00923909343026784 0.0712424892253023 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 112/3513 484/18639 0.231404958677686 1.22777028886803 0.00966738899186601 0.0741166489376394 GO:0001216 DNA-binding transcription activator activity 113/3513 491/18639 0.230142566191446 1.22107238577921 0.0110705284764125 0.0843890570716241 GO:0016854 racemase and epimerase activity 8/3513 18/18639 0.444444444444444 2.35809849131796 0.0113785216362128 0.086244021947204 GO:0042974 nuclear retinoic acid receptor binding 10/3513 25/18639 0.4 2.12228864218617 0.0114552353087652 0.0863349372988293 GO:0005548 phospholipid transporter activity 21/3513 68/18639 0.308823529411765 1.63853167227608 0.0115582739405333 0.086622120430738 GO:0004725 protein tyrosine phosphatase activity 28/3513 98/18639 0.285714285714286 1.5159204587044 0.0124426230576293 0.0927288221166342 GO:0004629 phospholipase C activity 11/3513 29/18639 0.379310344827586 2.01251509172826 0.0127473643079144 0.0944721332597653 GO:0032182 ubiquitin-like protein binding 33/3513 120/18639 0.275 1.45907344150299 0.0129128600822271 0.0951699190590659 GO:0015929 hexosaminidase activity 7/3513 15/18639 0.466666666666667 2.47600341588386 0.0130636719944763 0.0952291718067286 GO:0042809 nuclear vitamin D receptor binding 7/3513 15/18639 0.466666666666667 2.47600341588386 0.0130636719944763 0.0952291718067286 GO:0043539 protein serine/threonine kinase activator activity 22/3513 73/18639 0.301369863013699 1.59898459342793 0.013347791218211 0.0967714863320295 GO:0016279 protein-lysine N-methyltransferase activity 21/3513 69/18639 0.304347826086957 1.614784836446 0.0137337742933504 0.0990316481477269 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 6/3513 12/18639 0.5 2.65286080273271 0.0145361203607394 0.103696174124205 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 6/3513 12/18639 0.5 2.65286080273271 0.0145361203607394 0.103696174124205 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 14/3513 41/18639 0.341463414634146 1.81170981650039 0.0146914953402681 0.104247099914456 GO:0019199 transmembrane receptor protein kinase activity 23/3513 78/18639 0.294871794871795 1.56450765289365 0.0151575815748958 0.106485096939167 GO:0019209 kinase activator activity 39/3513 148/18639 0.263513513513513 1.39812934198075 0.0151665430423101 0.106485096939167 GO:1990782 protein tyrosine kinase binding 32/3513 117/18639 0.273504273504274 1.45113753311875 0.0153681068698697 0.107335364211551 GO:0050681 nuclear androgen receptor binding 10/3513 26/18639 0.384615384615385 2.04066215594824 0.015530948269745 0.107907734332499 GO:0019955 cytokine binding 38/3513 144/18639 0.263888888888889 1.40012097922004 0.0159945462823665 0.110552977930968 GO:0016278 lysine N-methyltransferase activity 21/3513 70/18639 0.3 1.59171648163962 0.0162211649806172 0.111349105059375 GO:0016791 phosphatase activity 66/3513 273/18639 0.241758241758242 1.28270192659603 0.0162766682807932 0.111349105059375 GO:0003756 protein disulfide isomerase activity 8/3513 19/18639 0.421052631578947 2.23398804440649 0.0164607907252852 0.111465455977312 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 8/3513 19/18639 0.421052631578947 2.23398804440649 0.0164607907252852 0.111465455977312 GO:0032452 histone demethylase activity 11/3513 30/18639 0.366666666666667 1.94543125533732 0.0167712302176293 0.112994046011704 GO:0008168 methyltransferase activity 51/3513 204/18639 0.25 1.32643040136635 0.0173844116622492 0.116536709333872 GO:0002020 protease binding 36/3513 136/18639 0.264705882352941 1.40445571909379 0.0177893385438301 0.118654888087347 GO:0008171 O-methyltransferase activity 9/3513 23/18639 0.391304347826087 2.07615193257342 0.0189107314220392 0.123058125448782 GO:0017134 fibroblast growth factor binding 9/3513 23/18639 0.391304347826087 2.07615193257342 0.0189107314220392 0.123058125448782 GO:0042171 lysophosphatidic acid acyltransferase activity 9/3513 23/18639 0.391304347826087 2.07615193257342 0.0189107314220392 0.123058125448782 GO:0071617 lysophospholipid acyltransferase activity 9/3513 23/18639 0.391304347826087 2.07615193257342 0.0189107314220392 0.123058125448782 GO:0140103 catalytic activity, acting on a glycoprotein 9/3513 23/18639 0.391304347826087 2.07615193257342 0.0189107314220392 0.123058125448782 GO:0004707 MAP kinase activity 7/3513 16/18639 0.4375 2.32125320239112 0.0195064257000543 0.125708076733683 GO:0015562 efflux transmembrane transporter activity 7/3513 16/18639 0.4375 2.32125320239112 0.0195064257000543 0.125708076733683 GO:0004386 helicase activity 40/3513 155/18639 0.258064516129032 1.36921847882978 0.0197381829889396 0.12659007743868 GO:0140034 methylation-dependent protein binding 22/3513 76/18639 0.289473684210526 1.53586678052946 0.0213634186353308 0.136357896935556 GO:0070273 phosphatidylinositol-4-phosphate binding 11/3513 31/18639 0.354838709677419 1.88267540839095 0.0216711610815711 0.137011037359317 GO:0140457 protein demethylase activity 11/3513 31/18639 0.354838709677419 1.88267540839095 0.0216711610815711 0.137011037359317 GO:0005518 collagen binding 21/3513 72/18639 0.291666666666667 1.54750213492741 0.0222446442679854 0.13933063259576 GO:0005154 epidermal growth factor receptor binding 12/3513 35/18639 0.342857142857143 1.81910455044528 0.0222895421220671 0.13933063259576 GO:0043495 protein-membrane adaptor activity 15/3513 47/18639 0.319148936170213 1.6933154059996 0.0223513908362014 0.13933063259576 GO:0008375 acetylglucosaminyltransferase activity 14/3513 43/18639 0.325581395348837 1.7274442436399 0.0225546257029666 0.139943584594221 GO:0043560 insulin receptor substrate binding 6/3513 13/18639 0.461538461538462 2.44879458713788 0.0227534043842968 0.140523340040055 GO:0015095 magnesium ion transmembrane transporter activity 8/3513 20/18639 0.4 2.12228864218617 0.0229929758682553 0.141348524461994 GO:0016410 N-acyltransferase activity 26/3513 94/18639 0.276595744680851 1.46754001853299 0.0234859984142185 0.143717072864988 GO:0030971 receptor tyrosine kinase binding 23/3513 81/18639 0.283950617283951 1.5065629250087 0.0236504607610932 0.144062623996796 GO:0004622 lysophospholipase activity 9/3513 24/18639 0.375 1.98964560204953 0.025311914953638 0.153261388479009 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 5/3513 10/18639 0.5 2.65286080273271 0.0257350457416027 0.153261388479009 GO:0005345 purine nucleobase transmembrane transporter activity 5/3513 10/18639 0.5 2.65286080273271 0.0257350457416027 0.153261388479009 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 5/3513 10/18639 0.5 2.65286080273271 0.0257350457416027 0.153261388479009 GO:0140999 histone H3K4 trimethyltransferase activity 5/3513 10/18639 0.5 2.65286080273271 0.0257350457416027 0.153261388479009 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 42/3513 167/18639 0.251497005988024 1.33437309838052 0.0261287032539411 0.154914178403367 GO:0046875 ephrin receptor binding 10/3513 28/18639 0.357142857142857 1.89490057338051 0.0267530810533255 0.157218546806768 GO:0141052 histone H3 demethylase activity 10/3513 28/18639 0.357142857142857 1.89490057338051 0.0267530810533255 0.157218546806768 GO:0001046 core promoter sequence-specific DNA binding 14/3513 44/18639 0.318181818181818 1.68818414719354 0.0274991633579467 0.15958849427083 GO:0004177 aminopeptidase activity 13/3513 40/18639 0.325 1.72435952177626 0.0278060008947427 0.15958849427083 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 7/3513 17/18639 0.411764705882353 2.18470889636811 0.0278741522976786 0.15958849427083 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 7/3513 17/18639 0.411764705882353 2.18470889636811 0.0278741522976786 0.15958849427083 GO:0019198 transmembrane receptor protein phosphatase activity 7/3513 17/18639 0.411764705882353 2.18470889636811 0.0278741522976786 0.15958849427083 GO:0046965 nuclear retinoid X receptor binding 7/3513 17/18639 0.411764705882353 2.18470889636811 0.0278741522976786 0.15958849427083 GO:0035064 methylated histone binding 21/3513 74/18639 0.283783783783784 1.50567775290235 0.0298556003728826 0.170202439732587 GO:0004601 peroxidase activity 17/3513 57/18639 0.298245614035088 1.58240819812126 0.0303009390967417 0.172006181936398 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 8/3513 21/18639 0.380952380952381 2.02122727827254 0.0311506845984484 0.17533760866806 GO:0010314 phosphatidylinositol-5-phosphate binding 8/3513 21/18639 0.380952380952381 2.02122727827254 0.0311506845984484 0.17533760866806 GO:1901505 carbohydrate derivative transmembrane transporter activity 16/3513 53/18639 0.30188679245283 1.60172727712163 0.0313534365796335 0.17573732940013 GO:0004709 MAP kinase kinase kinase activity 9/3513 25/18639 0.36 1.91005977796755 0.0331062972538789 0.184015835569477 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 9/3513 25/18639 0.36 1.91005977796755 0.0331062972538789 0.184015835569477 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 10/3513 29/18639 0.344827586206897 1.82955917429842 0.0341245109193314 0.187721725146597 GO:0035401 histone H3Y41 kinase activity 30/3513 115/18639 0.260869565217391 1.38410128838228 0.0343487546953538 0.187721725146597 GO:0140801 histone H2AXY142 kinase activity 30/3513 115/18639 0.260869565217391 1.38410128838228 0.0343487546953538 0.187721725146597 GO:0042805 actinin binding 12/3513 37/18639 0.324324324324324 1.72077457474554 0.0343544642455235 0.187721725146597 GO:0140416 transcription regulator inhibitor activity 11/3513 33/18639 0.333333333333333 1.76857386848847 0.0344766286813466 0.187721725146597 GO:0044389 ubiquitin-like protein ligase binding 74/3513 322/18639 0.229813664596273 1.21932732547963 0.0351033513897832 0.190357198186873 GO:0140299 molecular sensor activity 20/3513 71/18639 0.28169014084507 1.49456946632829 0.0360378866339807 0.194633768298503 GO:0016853 isomerase activity 44/3513 180/18639 0.244444444444444 1.29695417022488 0.0364252727213714 0.195932716977054 GO:0008525 phosphatidylcholine transporter activity 7/3513 18/18639 0.388888888888889 2.06333617990322 0.0383713718095206 0.204749639975602 GO:0030228 lipoprotein particle receptor activity 7/3513 18/18639 0.388888888888889 2.06333617990322 0.0383713718095206 0.204749639975602 GO:0008526 phosphatidylinositol transfer activity 5/3513 11/18639 0.454545454545455 2.41169163884792 0.0399885017401488 0.208377583286557 GO:0010854 adenylate cyclase regulator activity 5/3513 11/18639 0.454545454545455 2.41169163884792 0.0399885017401488 0.208377583286557 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 5/3513 11/18639 0.454545454545455 2.41169163884792 0.0399885017401488 0.208377583286557 GO:0015205 nucleobase transmembrane transporter activity 5/3513 11/18639 0.454545454545455 2.41169163884792 0.0399885017401488 0.208377583286557 GO:0032050 clathrin heavy chain binding 5/3513 11/18639 0.454545454545455 2.41169163884792 0.0399885017401488 0.208377583286557 GO:0043522 leucine zipper domain binding 5/3513 11/18639 0.454545454545455 2.41169163884792 0.0399885017401488 0.208377583286557 GO:0004520 DNA endonuclease activity 13/3513 42/18639 0.30952380952381 1.64224716359644 0.0408832547193141 0.211388611610717 GO:0035198 miRNA binding 13/3513 42/18639 0.30952380952381 1.64224716359644 0.0408832547193141 0.211388611610717 GO:0140784 metal ion sensor activity 8/3513 22/18639 0.363636363636364 1.92935331107833 0.041083608546193 0.211604377608577 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 17/3513 59/18639 0.288135593220339 1.52876724225275 0.0414726067812109 0.212786374792828 GO:0004435 phosphatidylinositol phospholipase C activity 9/3513 26/18639 0.346153846153846 1.83659594035341 0.042410893774891 0.215835642539963 GO:0015035 protein-disulfide reductase activity 11/3513 34/18639 0.323529411764706 1.71655699000352 0.0425523043388382 0.215835642539963 GO:0090482 vitamin transmembrane transporter activity 11/3513 34/18639 0.323529411764706 1.71655699000352 0.0425523043388382 0.215835642539963 GO:0047372 monoacylglycerol lipase activity 6/3513 15/18639 0.4 2.12228864218617 0.0472780560870584 0.238897450076272 GO:0004714 transmembrane receptor protein tyrosine kinase activity 17/3513 60/18639 0.283333333333333 1.5032877882152 0.0480501025306525 0.241882402927889 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 7/3513 19/18639 0.368421052631579 1.95473953885568 0.0511525441086579 0.250873139121138 GO:0005229 intracellularly calcium-gated chloride channel activity 7/3513 19/18639 0.368421052631579 1.95473953885568 0.0511525441086579 0.250873139121138 GO:0015245 fatty acid transmembrane transporter activity 7/3513 19/18639 0.368421052631579 1.95473953885568 0.0511525441086579 0.250873139121138 GO:0042800 histone H3K4 methyltransferase activity 7/3513 19/18639 0.368421052631579 1.95473953885568 0.0511525441086579 0.250873139121138 GO:0046527 glucosyltransferase activity 7/3513 19/18639 0.368421052631579 1.95473953885568 0.0511525441086579 0.250873139121138 GO:0046624 sphingolipid transporter activity 7/3513 19/18639 0.368421052631579 1.95473953885568 0.0511525441086579 0.250873139121138 GO:0141147 intracellularly calcium-gated channel activity 7/3513 19/18639 0.368421052631579 1.95473953885568 0.0511525441086579 0.250873139121138 GO:0061631 ubiquitin conjugating enzyme activity 11/3513 35/18639 0.314285714285714 1.66751250457484 0.0518394036881917 0.253310492747428 GO:0008327 methyl-CpG binding 10/3513 31/18639 0.32258064516129 1.71152309853723 0.0528630513599973 0.255727524559974 GO:0003887 DNA-directed DNA polymerase activity 8/3513 23/18639 0.347826086956522 1.84546838450971 0.0529091430124084 0.255727524559974 GO:0099186 structural constituent of postsynapse 8/3513 23/18639 0.347826086956522 1.84546838450971 0.0529091430124084 0.255727524559974 GO:0031491 nucleosome binding 20/3513 74/18639 0.27027027027027 1.43397881228795 0.0536157185941073 0.258207106875593 GO:0015026 coreceptor activity 17/3513 61/18639 0.278688524590164 1.47864372611331 0.0553316644399071 0.265512375405885 GO:0003995 acyl-CoA dehydrogenase activity 5/3513 12/18639 0.416666666666667 2.21071733561059 0.0581687741540127 0.275167179863308 GO:0035251 UDP-glucosyltransferase activity 5/3513 12/18639 0.416666666666667 2.21071733561059 0.0581687741540127 0.275167179863308 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 5/3513 12/18639 0.416666666666667 2.21071733561059 0.0581687741540127 0.275167179863308 GO:0070410 co-SMAD binding 5/3513 12/18639 0.416666666666667 2.21071733561059 0.0581687741540127 0.275167179863308 GO:0061775 cohesin loader activity 37/3513 153/18639 0.241830065359477 1.28308300262889 0.0590576966824925 0.278385043725954 GO:0008094 ATP-dependent activity, acting on DNA 49/3513 210/18639 0.233333333333333 1.23800170794193 0.059496453413356 0.278901877522886 GO:0140097 catalytic activity, acting on DNA 75/3513 336/18639 0.223214285714286 1.18431285836282 0.0601006487984675 0.278901877522886 GO:0015036 disulfide oxidoreductase activity 12/3513 40/18639 0.3 1.59171648163962 0.0601530543335535 0.278901877522886 GO:0032451 demethylase activity 12/3513 40/18639 0.3 1.59171648163962 0.0601530543335535 0.278901877522886 GO:0051219 phosphoprotein binding 24/3513 93/18639 0.258064516129032 1.36921847882978 0.0602126991953457 0.278901877522886 GO:0140658 ATP-dependent chromatin remodeler activity 38/3513 158/18639 0.240506329113924 1.27605962663092 0.0605111719796125 0.279314544708661 GO:0001217 DNA-binding transcription repressor activity 63/3513 278/18639 0.226618705035971 1.20237575951195 0.061640494652245 0.283546275400327 GO:0000993 RNA polymerase II complex binding 11/3513 36/18639 0.305555555555556 1.6211927127811 0.0623938696161378 0.28498615880349 GO:0005484 SNAP receptor activity 11/3513 36/18639 0.305555555555556 1.6211927127811 0.0623938696161378 0.28498615880349 GO:0008170 N-methyltransferase activity 25/3513 98/18639 0.255102040816327 1.3535004095575 0.0630532676906828 0.28498615880349 GO:0003727 single-stranded RNA binding 23/3513 89/18639 0.258426966292135 1.37114153849106 0.0638937850386675 0.28498615880349 GO:0005024 transforming growth factor beta receptor activity 6/3513 16/18639 0.375 1.98964560204953 0.063941034319261 0.28498615880349 GO:0005324 long-chain fatty acid transmembrane transporter activity 6/3513 16/18639 0.375 1.98964560204953 0.063941034319261 0.28498615880349 GO:0030275 LRR domain binding 6/3513 16/18639 0.375 1.98964560204953 0.063941034319261 0.28498615880349 GO:0031435 mitogen-activated protein kinase kinase kinase binding 6/3513 16/18639 0.375 1.98964560204953 0.063941034319261 0.28498615880349 GO:0070411 I-SMAD binding 6/3513 16/18639 0.375 1.98964560204953 0.063941034319261 0.28498615880349 GO:0071813 lipoprotein particle binding 10/3513 32/18639 0.3125 1.65803800170794 0.0643721164408918 0.28498615880349 GO:0071814 protein-lipid complex binding 10/3513 32/18639 0.3125 1.65803800170794 0.0643721164408918 0.28498615880349 GO:0016763 pentosyltransferase activity 14/3513 49/18639 0.285714285714286 1.5159204587044 0.0645171064157826 0.28498615880349 GO:0005326 neurotransmitter transmembrane transporter activity 7/3513 20/18639 0.35 1.85700256191289 0.0663153885457975 0.291002395789783 GO:0010851 cyclase regulator activity 7/3513 20/18639 0.35 1.85700256191289 0.0663153885457975 0.291002395789783 GO:0016779 nucleotidyltransferase activity 33/3513 136/18639 0.242647058823529 1.28741774250264 0.0685680570987546 0.299900944818815 GO:0003925 G protein activity 15/3513 54/18639 0.277777777777778 1.47381155707373 0.0707212849330412 0.307303563845853 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 15/3513 54/18639 0.277777777777778 1.47381155707373 0.0707212849330412 0.307303563845853 GO:0015293 symporter activity 35/3513 146/18639 0.23972602739726 1.27191956295404 0.0720002568952737 0.311845268500958 GO:0000510 H3-H4 histone complex chaperone activity 36/3513 151/18639 0.23841059602649 1.26494025030964 0.0735941566226183 0.314662195303118 GO:0140584 chromatin extrusion motor activity 36/3513 151/18639 0.23841059602649 1.26494025030964 0.0735941566226183 0.314662195303118 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 36/3513 151/18639 0.23841059602649 1.26494025030964 0.0735941566226183 0.314662195303118 GO:0140849 ATP-dependent H2AZ histone chaperone activity 36/3513 151/18639 0.23841059602649 1.26494025030964 0.0735941566226183 0.314662195303118 GO:0004721 phosphoprotein phosphatase activity 41/3513 175/18639 0.234285714285714 1.24305477613761 0.0748897801268766 0.319178807313909 GO:0031593 polyubiquitin modification-dependent protein binding 16/3513 59/18639 0.271186440677966 1.43883975741435 0.076419667411645 0.323631226435347 GO:0070063 RNA polymerase binding 16/3513 59/18639 0.271186440677966 1.43883975741435 0.076419667411645 0.323631226435347 GO:0015616 DNA translocase activity 36/3513 152/18639 0.236842105263158 1.25661827497865 0.0795808837869731 0.330146270952731 GO:0140674 ATP-dependent histone chaperone activity 36/3513 152/18639 0.236842105263158 1.25661827497865 0.0795808837869731 0.330146270952731 GO:0016417 S-acyltransferase activity 9/3513 29/18639 0.310344827586207 1.64660325686858 0.0802067817324986 0.330146270952731 GO:0051861 glycolipid binding 9/3513 29/18639 0.310344827586207 1.64660325686858 0.0802067817324986 0.330146270952731 GO:0004535 poly(A)-specific ribonuclease activity 5/3513 13/18639 0.384615384615385 2.04066215594824 0.080303380260085 0.330146270952731 GO:0005172 vascular endothelial growth factor receptor binding 5/3513 13/18639 0.384615384615385 2.04066215594824 0.080303380260085 0.330146270952731 GO:0005338 nucleotide-sugar transmembrane transporter activity 5/3513 13/18639 0.384615384615385 2.04066215594824 0.080303380260085 0.330146270952731 GO:0070123 transforming growth factor beta receptor activity, type III 5/3513 13/18639 0.384615384615385 2.04066215594824 0.080303380260085 0.330146270952731 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 60/3513 268/18639 0.223880597014925 1.18784812062659 0.0807604456153985 0.330146270952731 GO:0004536 DNA nuclease activity 17/3513 64/18639 0.265625 1.40933230145175 0.0816533212916449 0.330146270952731 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 42/3513 181/18639 0.232044198895028 1.23116191950026 0.0816807488912276 0.330146270952731 GO:0000030 mannosyltransferase activity 8/3513 25/18639 0.32 1.69783091374893 0.0825202087066946 0.330146270952731 GO:0017056 structural constituent of nuclear pore 8/3513 25/18639 0.32 1.69783091374893 0.0825202087066946 0.330146270952731 GO:0019706 protein-cysteine S-palmitoyltransferase activity 8/3513 25/18639 0.32 1.69783091374893 0.0825202087066946 0.330146270952731 GO:0019707 protein-cysteine S-acyltransferase activity 8/3513 25/18639 0.32 1.69783091374893 0.0825202087066946 0.330146270952731 GO:0043175 RNA polymerase core enzyme binding 12/3513 42/18639 0.285714285714286 1.5159204587044 0.0830726070912189 0.330146270952731 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 6/3513 17/18639 0.352941176470588 1.87260762545838 0.0836138790583058 0.330146270952731 GO:0017110 nucleoside diphosphate phosphatase activity 6/3513 17/18639 0.352941176470588 1.87260762545838 0.0836138790583058 0.330146270952731 GO:0030169 low-density lipoprotein particle binding 6/3513 17/18639 0.352941176470588 1.87260762545838 0.0836138790583058 0.330146270952731 GO:0038191 neuropilin binding 6/3513 17/18639 0.352941176470588 1.87260762545838 0.0836138790583058 0.330146270952731 GO:0008081 phosphoric diester hydrolase activity 22/3513 87/18639 0.252873563218391 1.34167672781884 0.0838380745206803 0.330146270952731 GO:0051010 microtubule plus-end binding 7/3513 21/18639 0.333333333333333 1.76857386848847 0.0838977405194722 0.330146270952731 GO:0061891 calcium ion sensor activity 7/3513 21/18639 0.333333333333333 1.76857386848847 0.0838977405194722 0.330146270952731 GO:0140312 cargo adaptor activity 7/3513 21/18639 0.333333333333333 1.76857386848847 0.0838977405194722 0.330146270952731 GO:0016887 ATP hydrolysis activity 90/3513 417/18639 0.215827338129496 1.14511977096376 0.0852369245456824 0.334429580423354 GO:0042162 telomeric DNA binding 11/3513 38/18639 0.289473684210526 1.53586678052946 0.0874527282920977 0.341116782285551 GO:0042887 amide transmembrane transporter activity 11/3513 38/18639 0.289473684210526 1.53586678052946 0.0874527282920977 0.341116782285551 GO:0008376 acetylgalactosaminyltransferase activity 10/3513 34/18639 0.294117647058824 1.56050635454865 0.0918775922048734 0.357331510207875 GO:0015294 solute:monoatomic cation symporter activity 28/3513 116/18639 0.241379310344828 1.28069142200889 0.0924181813107747 0.357874621107095 GO:0005319 lipid transporter activity 41/3513 178/18639 0.230337078651685 1.22210441474203 0.0925537813208004 0.357874621107095 GO:0008238 exopeptidase activity 25/3513 102/18639 0.245098039215686 1.30042196212388 0.0930541600071374 0.358769507079541 GO:0140597 protein carrier chaperone 43/3513 188/18639 0.228723404255319 1.21354270763305 0.0947570895797366 0.363686062698609 GO:0140713 histone chaperone activity 38/3513 164/18639 0.231707317073171 1.22937451833955 0.0953538279750293 0.363686062698609 GO:0019888 protein phosphatase regulator activity 26/3513 107/18639 0.242990654205607 1.28924076394487 0.0957229632044523 0.363686062698609 GO:0001968 fibronectin binding 9/3513 30/18639 0.3 1.59171648163962 0.0962377662163485 0.363686062698609 GO:0008187 poly-pyrimidine tract binding 9/3513 30/18639 0.3 1.59171648163962 0.0962377662163485 0.363686062698609 GO:0031210 phosphatidylcholine binding 9/3513 30/18639 0.3 1.59171648163962 0.0962377662163485 0.363686062698609 GO:0098918 structural constituent of synapse 9/3513 30/18639 0.3 1.59171648163962 0.0962377662163485 0.363686062698609 GO:0030159 signaling receptor complex adaptor activity 14/3513 52/18639 0.269230769230769 1.42846350916377 0.0979672006649969 0.36917583527431 GO:0120014 phospholipid transfer activity 8/3513 26/18639 0.307692307692308 1.63252972475859 0.100346570898607 0.369603661111709 GO:0019208 phosphatase regulator activity 28/3513 117/18639 0.239316239316239 1.2697453414789 0.10054363654262 0.369603661111709 GO:0003689 DNA clamp loader activity 37/3513 160/18639 0.23125 1.22694812126388 0.100930259716382 0.369603661111709 GO:0004382 GDP phosphatase activity 4/3513 10/18639 0.4 2.12228864218617 0.101405502224052 0.369603661111709 GO:0005131 growth hormone receptor binding 4/3513 10/18639 0.4 2.12228864218617 0.101405502224052 0.369603661111709 GO:0005522 profilin binding 4/3513 10/18639 0.4 2.12228864218617 0.101405502224052 0.369603661111709 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 4/3513 10/18639 0.4 2.12228864218617 0.101405502224052 0.369603661111709 GO:0019911 structural constituent of myelin sheath 4/3513 10/18639 0.4 2.12228864218617 0.101405502224052 0.369603661111709 GO:0031720 haptoglobin binding 4/3513 10/18639 0.4 2.12228864218617 0.101405502224052 0.369603661111709 GO:0042975 peroxisome proliferator activated receptor binding 4/3513 10/18639 0.4 2.12228864218617 0.101405502224052 0.369603661111709 GO:0045322 unmethylated CpG binding 4/3513 10/18639 0.4 2.12228864218617 0.101405502224052 0.369603661111709 GO:0051880 G-quadruplex DNA binding 4/3513 10/18639 0.4 2.12228864218617 0.101405502224052 0.369603661111709 GO:0031625 ubiquitin protein ligase binding 66/3513 302/18639 0.218543046357616 1.15952856278383 0.103007500727154 0.371054471319278 GO:0004407 histone deacetylase activity 7/3513 22/18639 0.318181818181818 1.68818414719354 0.103877668773669 0.371054471319278 GO:0033558 protein lysine deacetylase activity 7/3513 22/18639 0.318181818181818 1.68818414719354 0.103877668773669 0.371054471319278 GO:0036121 double-stranded DNA helicase activity 13/3513 48/18639 0.270833333333333 1.43696626814688 0.104166777205858 0.371054471319278 GO:0015932 nucleobase-containing compound transmembrane transporter activity 15/3513 57/18639 0.263157894736842 1.39624252775406 0.104264795438035 0.371054471319278 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 6/3513 18/18639 0.333333333333333 1.76857386848847 0.106235132682699 0.371054471319278 GO:0004706 JUN kinase kinase kinase activity 6/3513 18/18639 0.333333333333333 1.76857386848847 0.106235132682699 0.371054471319278 GO:0034185 apolipoprotein binding 6/3513 18/18639 0.333333333333333 1.76857386848847 0.106235132682699 0.371054471319278 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 6/3513 18/18639 0.333333333333333 1.76857386848847 0.106235132682699 0.371054471319278 GO:1901611 phosphatidylglycerol binding 6/3513 18/18639 0.333333333333333 1.76857386848847 0.106235132682699 0.371054471319278 GO:0004705 JUN kinase activity 5/3513 14/18639 0.357142857142857 1.89490057338051 0.106253979043452 0.371054471319278 GO:0005344 oxygen carrier activity 5/3513 14/18639 0.357142857142857 1.89490057338051 0.106253979043452 0.371054471319278 GO:0005545 1-phosphatidylinositol binding 5/3513 14/18639 0.357142857142857 1.89490057338051 0.106253979043452 0.371054471319278 GO:0008559 ABC-type xenobiotic transporter activity 5/3513 14/18639 0.357142857142857 1.89490057338051 0.106253979043452 0.371054471319278 GO:0015926 glucosidase activity 5/3513 14/18639 0.357142857142857 1.89490057338051 0.106253979043452 0.371054471319278 GO:0070742 C2H2 zinc finger domain binding 5/3513 14/18639 0.357142857142857 1.89490057338051 0.106253979043452 0.371054471319278 GO:0043015 gamma-tubulin binding 10/3513 35/18639 0.285714285714286 1.5159204587044 0.107892867611546 0.375793956641781 GO:0043014 alpha-tubulin binding 12/3513 44/18639 0.272727272727273 1.44701498330875 0.110789661773135 0.384878668763962 GO:0031490 chromatin DNA binding 30/3513 128/18639 0.234375 1.24352850128096 0.113197466319283 0.39222187031149 GO:0016411 acylglycerol O-acyltransferase activity 9/3513 31/18639 0.290322580645161 1.54037078868351 0.113981967748492 0.393916955897638 GO:0008173 RNA methyltransferase activity 17/3513 67/18639 0.253731343283582 1.34622787004346 0.115016387189406 0.396464755841519 GO:0008408 3'-5' exonuclease activity 15/3513 58/18639 0.258620689655172 1.37216938072381 0.117284201372074 0.402203405219401 GO:0061980 regulatory RNA binding 15/3513 58/18639 0.258620689655172 1.37216938072381 0.117284201372074 0.402203405219401 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 11/3513 40/18639 0.275 1.45907344150299 0.117859091808001 0.403138534543266 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 21/3513 86/18639 0.244186046511628 1.29558318272993 0.119606975820988 0.408070858683372 GO:0008266 poly(U) RNA binding 8/3513 27/18639 0.296296296296296 1.57206566087864 0.120146930239647 0.408867359540024 GO:0004896 cytokine receptor activity 23/3513 96/18639 0.239583333333333 1.27116246797609 0.125872217075574 0.427014679207993 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 7/3513 23/18639 0.304347826086957 1.614784836446 0.126176398794221 0.427014679207993 GO:0140303 intramembrane lipid transporter activity 12/3513 45/18639 0.266666666666667 1.41485909479078 0.12643987877598 0.427014679207993 GO:0015291 secondary active transmembrane transporter activity 62/3513 287/18639 0.21602787456446 1.14618376145943 0.130667686891289 0.43772173569722 GO:0001786 phosphatidylserine binding 15/3513 59/18639 0.254237288135593 1.34891227257595 0.131215292494948 0.43772173569722 GO:0043395 heparan sulfate proteoglycan binding 6/3513 19/18639 0.315789473684211 1.67549103330487 0.131657865870717 0.43772173569722 GO:0140036 ubiquitin-modified protein reader activity 6/3513 19/18639 0.315789473684211 1.67549103330487 0.131657865870717 0.43772173569722 GO:0051059 NF-kappaB binding 9/3513 32/18639 0.28125 1.49223420153715 0.133394518260162 0.43772173569722 GO:0070717 poly-purine tract binding 9/3513 32/18639 0.28125 1.49223420153715 0.133394518260162 0.43772173569722 GO:0005007 fibroblast growth factor receptor activity 13/3513 50/18639 0.26 1.37948761742101 0.1338763448881 0.43772173569722 GO:0005017 platelet-derived growth factor receptor activity 13/3513 50/18639 0.26 1.37948761742101 0.1338763448881 0.43772173569722 GO:0005019 platelet-derived growth factor beta-receptor activity 13/3513 50/18639 0.26 1.37948761742101 0.1338763448881 0.43772173569722 GO:0015605 organophosphate ester transmembrane transporter activity 13/3513 50/18639 0.26 1.37948761742101 0.1338763448881 0.43772173569722 GO:0061650 ubiquitin-like protein conjugating enzyme activity 11/3513 41/18639 0.268292682926829 1.42348628439316 0.135033973119307 0.43772173569722 GO:0005041 low-density lipoprotein particle receptor activity 5/3513 15/18639 0.333333333333333 1.76857386848847 0.135741940521648 0.43772173569722 GO:0050780 dopamine receptor binding 5/3513 15/18639 0.333333333333333 1.76857386848847 0.135741940521648 0.43772173569722 GO:0016176 superoxide-generating NADPH oxidase activator activity 4/3513 11/18639 0.363636363636364 1.92935331107833 0.136500931071997 0.43772173569722 GO:0032794 GTPase activating protein binding 4/3513 11/18639 0.363636363636364 1.92935331107833 0.136500931071997 0.43772173569722 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 4/3513 11/18639 0.363636363636364 1.92935331107833 0.136500931071997 0.43772173569722 GO:0034713 type I transforming growth factor beta receptor binding 4/3513 11/18639 0.363636363636364 1.92935331107833 0.136500931071997 0.43772173569722 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 4/3513 11/18639 0.363636363636364 1.92935331107833 0.136500931071997 0.43772173569722 GO:0047676 arachidonate-CoA ligase activity 4/3513 11/18639 0.363636363636364 1.92935331107833 0.136500931071997 0.43772173569722 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 4/3513 11/18639 0.363636363636364 1.92935331107833 0.136500931071997 0.43772173569722 GO:0140537 transcription regulator activator activity 4/3513 11/18639 0.363636363636364 1.92935331107833 0.136500931071997 0.43772173569722 GO:0051119 sugar transmembrane transporter activity 8/3513 28/18639 0.285714285714286 1.5159204587044 0.141843547398624 0.451597356156957 GO:0051393 alpha-actinin binding 8/3513 28/18639 0.285714285714286 1.5159204587044 0.141843547398624 0.451597356156957 GO:0097718 disordered domain specific binding 8/3513 28/18639 0.285714285714286 1.5159204587044 0.141843547398624 0.451597356156957 GO:0140104 molecular carrier activity 54/3513 249/18639 0.216867469879518 1.15063842046238 0.142344873424403 0.451745814554199 GO:0140789 histone phosphatase activity 31/3513 136/18639 0.227941176470588 1.2093924247752 0.14256745721688 0.451745814554199 GO:0004197 cysteine-type endopeptidase activity 21/3513 88/18639 0.238636363636364 1.26613811039516 0.142984630398012 0.451994068604141 GO:0043394 proteoglycan binding 10/3513 37/18639 0.27027027027027 1.43397881228795 0.144331662691802 0.455173612366107 GO:0001098 basal transcription machinery binding 15/3513 60/18639 0.25 1.32643040136635 0.146041765718959 0.457323275749042 GO:0001099 basal RNA polymerase II transcription machinery binding 15/3513 60/18639 0.25 1.32643040136635 0.146041765718959 0.457323275749042 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 15/3513 60/18639 0.25 1.32643040136635 0.146041765718959 0.457323275749042 GO:0042626 ATPase-coupled transmembrane transporter activity 23/3513 98/18639 0.23469387755102 1.2452203767929 0.148603675544652 0.46425597933622 GO:0005010 insulin-like growth factor receptor activity 13/3513 51/18639 0.254901960784314 1.35243884060883 0.15031534816681 0.465243266413332 GO:0005021 vascular endothelial growth factor receptor activity 13/3513 51/18639 0.254901960784314 1.35243884060883 0.15031534816681 0.465243266413332 GO:0015295 solute:proton symporter activity 7/3513 24/18639 0.291666666666667 1.54750213492741 0.150663486574632 0.465243266413332 GO:0030215 semaphorin receptor binding 7/3513 24/18639 0.291666666666667 1.54750213492741 0.150663486574632 0.465243266413332 GO:0050431 transforming growth factor beta binding 7/3513 24/18639 0.291666666666667 1.54750213492741 0.150663486574632 0.465243266413332 GO:0031492 nucleosomal DNA binding 11/3513 42/18639 0.261904761904762 1.38959375381237 0.15347187719379 0.472820979622438 GO:0022804 active transmembrane transporter activity 95/3513 457/18639 0.207877461706783 1.10293993986699 0.155499263455494 0.477963173847071 GO:0170055 lipid transmembrane transporter activity 14/3513 56/18639 0.25 1.32643040136635 0.156424278828538 0.479701121740849 GO:0001614 purinergic nucleotide receptor activity 6/3513 20/18639 0.3 1.59171648163962 0.159661784724254 0.486275846625925 GO:0016502 nucleotide receptor activity 6/3513 20/18639 0.3 1.59171648163962 0.159661784724254 0.486275846625925 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 6/3513 20/18639 0.3 1.59171648163962 0.159661784724254 0.486275846625925 GO:0001784 phosphotyrosine residue binding 12/3513 47/18639 0.25531914893617 1.35465232479968 0.161190076415356 0.487590843397018 GO:0061749 forked DNA-dependent helicase activity 12/3513 47/18639 0.25531914893617 1.35465232479968 0.161190076415356 0.487590843397018 GO:1990518 single-stranded 3'-5' DNA helicase activity 12/3513 47/18639 0.25531914893617 1.35465232479968 0.161190076415356 0.487590843397018 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 10/3513 38/18639 0.263157894736842 1.39624252775406 0.164645567834553 0.496717363793861 GO:0035250 UDP-galactosyltransferase activity 8/3513 29/18639 0.275862068965517 1.46364733943873 0.165324220033339 0.496717363793861 GO:0043236 laminin binding 8/3513 29/18639 0.275862068965517 1.46364733943873 0.165324220033339 0.496717363793861 GO:0005080 protein kinase C binding 13/3513 52/18639 0.25 1.32643040136635 0.167764730667414 0.502499345044657 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 5/3513 16/18639 0.3125 1.65803800170794 0.168378716068187 0.502499345044657 GO:0034450 ubiquitin-ubiquitin ligase activity 5/3513 16/18639 0.3125 1.65803800170794 0.168378716068187 0.502499345044657 GO:0005025 transforming growth factor beta receptor activity, type I 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0005026 transforming growth factor beta receptor activity, type II 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0005165 neurotrophin receptor binding 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0008179 adenylate cyclase binding 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0008504 monoamine transmembrane transporter activity 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0008603 cAMP-dependent protein kinase regulator activity 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0010853 cyclase activator activity 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0016361 activin receptor activity, type I 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0016362 activin receptor activity, type II 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0017002 activin receptor activity 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0017166 vinculin binding 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0035014 phosphatidylinositol 3-kinase regulator activity 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0035259 nuclear glucocorticoid receptor binding 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0045295 gamma-catenin binding 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 4/3513 12/18639 0.333333333333333 1.76857386848847 0.175667009530989 0.503268635211049 GO:0005537 D-mannose binding 7/3513 25/18639 0.28 1.48560204953032 0.177163650189941 0.503268635211049 GO:0015296 monoatomic anion:monoatomic cation symporter activity 7/3513 25/18639 0.28 1.48560204953032 0.177163650189941 0.503268635211049 GO:0019211 phosphatase activator activity 7/3513 25/18639 0.28 1.48560204953032 0.177163650189941 0.503268635211049 GO:0120020 cholesterol transfer activity 7/3513 25/18639 0.28 1.48560204953032 0.177163650189941 0.503268635211049 GO:0004222 metalloendopeptidase activity 25/3513 110/18639 0.227272727272727 1.20584581942396 0.177313537143323 0.503268635211049 GO:0008237 metallopeptidase activity 40/3513 184/18639 0.217391304347826 1.15341774031857 0.179647884078758 0.505008240167876 GO:0016209 antioxidant activity 20/3513 86/18639 0.232558139534884 1.23388874545707 0.180057005500768 0.505008240167876 GO:0050660 flavin adenine dinucleotide binding 20/3513 86/18639 0.232558139534884 1.23388874545707 0.180057005500768 0.505008240167876 GO:0009378 four-way junction helicase activity 12/3513 48/18639 0.25 1.32643040136635 0.180197842818522 0.505008240167876 GO:0043138 3'-5' DNA helicase activity 12/3513 48/18639 0.25 1.32643040136635 0.180197842818522 0.505008240167876 GO:0140693 molecular condensate scaffold activity 12/3513 48/18639 0.25 1.32643040136635 0.180197842818522 0.505008240167876 GO:0050840 extracellular matrix binding 16/3513 67/18639 0.238805970149254 1.26703799533502 0.182503687110065 0.510398152211378 GO:0005003 ephrin receptor activity 13/3513 53/18639 0.245283018867925 1.30140341266133 0.186177410708444 0.515271091047851 GO:0005005 transmembrane-ephrin receptor activity 13/3513 53/18639 0.245283018867925 1.30140341266133 0.186177410708444 0.515271091047851 GO:0005544 calcium-dependent phospholipid binding 13/3513 53/18639 0.245283018867925 1.30140341266133 0.186177410708444 0.515271091047851 GO:0016860 intramolecular oxidoreductase activity 13/3513 53/18639 0.245283018867925 1.30140341266133 0.186177410708444 0.515271091047851 GO:0140296 general transcription initiation factor binding 13/3513 53/18639 0.245283018867925 1.30140341266133 0.186177410708444 0.515271091047851 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 6/3513 21/18639 0.285714285714286 1.5159204587044 0.189967402406167 0.520362453408269 GO:0005123 death receptor binding 6/3513 21/18639 0.285714285714286 1.5159204587044 0.189967402406167 0.520362453408269 GO:0019200 carbohydrate kinase activity 6/3513 21/18639 0.285714285714286 1.5159204587044 0.189967402406167 0.520362453408269 GO:0036122 BMP binding 6/3513 21/18639 0.285714285714286 1.5159204587044 0.189967402406167 0.520362453408269 GO:0072542 protein phosphatase activator activity 6/3513 21/18639 0.285714285714286 1.5159204587044 0.189967402406167 0.520362453408269 GO:0001965 G-protein alpha-subunit binding 8/3513 30/18639 0.266666666666667 1.41485909479078 0.190446566875881 0.520605984041855 GO:0017116 single-stranded DNA helicase activity 14/3513 58/18639 0.241379310344828 1.28069142200889 0.191263510933125 0.521769986880959 GO:0043178 alcohol binding 21/3513 92/18639 0.228260869565217 1.2110886273345 0.196882517918157 0.532551455424081 GO:0030145 manganese ion binding 16/3513 68/18639 0.235294117647059 1.24840508363892 0.199359020139174 0.532551455424081 GO:0005004 GPI-linked ephrin receptor activity 12/3513 49/18639 0.244897959183673 1.2993603931752 0.200212911663432 0.532551455424081 GO:0005008 hepatocyte growth factor receptor activity 12/3513 49/18639 0.244897959183673 1.2993603931752 0.200212911663432 0.532551455424081 GO:0005009 insulin receptor activity 12/3513 49/18639 0.244897959183673 1.2993603931752 0.200212911663432 0.532551455424081 GO:0005011 macrophage colony-stimulating factor receptor activity 12/3513 49/18639 0.244897959183673 1.2993603931752 0.200212911663432 0.532551455424081 GO:0005018 platelet-derived growth factor alpha-receptor activity 12/3513 49/18639 0.244897959183673 1.2993603931752 0.200212911663432 0.532551455424081 GO:0005020 stem cell factor receptor activity 12/3513 49/18639 0.244897959183673 1.2993603931752 0.200212911663432 0.532551455424081 GO:0008288 boss receptor activity 12/3513 49/18639 0.244897959183673 1.2993603931752 0.200212911663432 0.532551455424081 GO:0036332 placental growth factor receptor activity 12/3513 49/18639 0.244897959183673 1.2993603931752 0.200212911663432 0.532551455424081 GO:0038062 protein tyrosine kinase collagen receptor activity 12/3513 49/18639 0.244897959183673 1.2993603931752 0.200212911663432 0.532551455424081 GO:0060175 brain-derived neurotrophic factor receptor activity 12/3513 49/18639 0.244897959183673 1.2993603931752 0.200212911663432 0.532551455424081 GO:0000175 3'-5'-RNA exonuclease activity 9/3513 35/18639 0.257142857142857 1.36432841283396 0.200804634241614 0.532551455424081 GO:0034061 DNA polymerase activity 9/3513 35/18639 0.257142857142857 1.36432841283396 0.200804634241614 0.532551455424081 GO:0001637 G protein-coupled chemoattractant receptor activity 7/3513 26/18639 0.269230769230769 1.42846350916377 0.205464679402538 0.538571623720388 GO:0004950 chemokine receptor activity 7/3513 26/18639 0.269230769230769 1.42846350916377 0.205464679402538 0.538571623720388 GO:0015145 monosaccharide transmembrane transporter activity 7/3513 26/18639 0.269230769230769 1.42846350916377 0.205464679402538 0.538571623720388 GO:0070006 metalloaminopeptidase activity 7/3513 26/18639 0.269230769230769 1.42846350916377 0.205464679402538 0.538571623720388 GO:0015485 cholesterol binding 13/3513 54/18639 0.240740740740741 1.2773033494639 0.205496968870823 0.538571623720388 GO:0051287 NAD binding 13/3513 54/18639 0.240740740740741 1.2773033494639 0.205496968870823 0.538571623720388 GO:0030165 PDZ domain binding 19/3513 83/18639 0.228915662650602 1.21456277715473 0.207811259444918 0.543569059018669 GO:0004532 RNA exonuclease activity 10/3513 40/18639 0.25 1.32643040136635 0.209048248961576 0.543819162410655 GO:0015144 carbohydrate transmembrane transporter activity 10/3513 40/18639 0.25 1.32643040136635 0.209048248961576 0.543819162410655 GO:0008201 heparin binding 37/3513 172/18639 0.215116279069767 1.14134708954779 0.209866210350222 0.543819162410655 GO:0008234 cysteine-type peptidase activity 40/3513 187/18639 0.213903743315508 1.13491371239902 0.209940332158914 0.543819162410655 GO:0045309 protein phosphorylated amino acid binding 14/3513 59/18639 0.23728813559322 1.25898478773756 0.20994517889167 0.543819162410655 GO:0004843 cysteine-type deubiquitinase activity 24/3513 108/18639 0.222222222222222 1.17904924565898 0.215885683782452 0.554056813167957 GO:0017154 semaphorin receptor activity 4/3513 13/18639 0.307692307692308 1.63252972475859 0.218050844762502 0.554056813167957 GO:0046975 histone H3K36 methyltransferase activity 4/3513 13/18639 0.307692307692308 1.63252972475859 0.218050844762502 0.554056813167957 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 4/3513 13/18639 0.307692307692308 1.63252972475859 0.218050844762502 0.554056813167957 GO:0071714 icosanoid transmembrane transporter activity 4/3513 13/18639 0.307692307692308 1.63252972475859 0.218050844762502 0.554056813167957 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 4/3513 13/18639 0.307692307692308 1.63252972475859 0.218050844762502 0.554056813167957 GO:0140410 monoatomic cation:bicarbonate symporter activity 4/3513 13/18639 0.307692307692308 1.63252972475859 0.218050844762502 0.554056813167957 GO:0140666 annealing activity 4/3513 13/18639 0.307692307692308 1.63252972475859 0.218050844762502 0.554056813167957 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 4/3513 13/18639 0.307692307692308 1.63252972475859 0.218050844762502 0.554056813167957 GO:0140852 histone ubiquitin ligase activity 4/3513 13/18639 0.307692307692308 1.63252972475859 0.218050844762502 0.554056813167957 GO:0003678 DNA helicase activity 17/3513 74/18639 0.22972972972973 1.21888199044476 0.219642033331471 0.557038921034566 GO:0005006 epidermal growth factor receptor activity 12/3513 50/18639 0.24 1.2733731853117 0.221161301171432 0.557298691841136 GO:0008649 rRNA methyltransferase activity 6/3513 22/18639 0.272727272727273 1.44701498330875 0.222251052518354 0.557298691841136 GO:0015377 chloride:monoatomic cation symporter activity 6/3513 22/18639 0.272727272727273 1.44701498330875 0.222251052518354 0.557298691841136 GO:0070034 telomerase RNA binding 6/3513 22/18639 0.272727272727273 1.44701498330875 0.222251052518354 0.557298691841136 GO:0140035 ubiquitin-like protein reader activity 6/3513 22/18639 0.272727272727273 1.44701498330875 0.222251052518354 0.557298691841136 GO:0140517 protein-RNA adaptor activity 6/3513 22/18639 0.272727272727273 1.44701498330875 0.222251052518354 0.557298691841136 GO:0004527 exonuclease activity 19/3513 84/18639 0.226190476190476 1.20010369647432 0.223964110532253 0.560540569324625 GO:0098632 cell-cell adhesion mediator activity 13/3513 55/18639 0.236363636363636 1.25407965220092 0.225658541674661 0.563723772647936 GO:0120013 lipid transfer activity 15/3513 65/18639 0.230769230769231 1.22439729356894 0.232510800805752 0.579702198320467 GO:0042169 SH2 domain binding 10/3513 41/18639 0.24390243902439 1.29407844035742 0.232923821813921 0.579702198320467 GO:0008028 monocarboxylic acid transmembrane transporter activity 16/3513 70/18639 0.228571428571429 1.21273636696352 0.235118187806848 0.582420666803597 GO:0004683 calcium/calmodulin-dependent protein kinase activity 7/3513 27/18639 0.259259259259259 1.37555745326881 0.235325891609549 0.582420666803597 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 7/3513 27/18639 0.259259259259259 1.37555745326881 0.235325891609549 0.582420666803597 GO:0003725 double-stranded RNA binding 17/3513 75/18639 0.226666666666667 1.20263023057216 0.237301363920618 0.58622225827797 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 11/3513 46/18639 0.239130434782609 1.26875951435043 0.238484061292302 0.588054968140352 GO:0008017 microtubule binding 57/3513 276/18639 0.206521739130435 1.09574685330264 0.241080888701135 0.588186413938908 GO:0003746 translation elongation factor activity 5/3513 18/18639 0.277777777777778 1.47381155707373 0.241182884875999 0.588186413938908 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 5/3513 18/18639 0.277777777777778 1.47381155707373 0.241182884875999 0.588186413938908 GO:0017075 syntaxin-1 binding 5/3513 18/18639 0.277777777777778 1.47381155707373 0.241182884875999 0.588186413938908 GO:0017128 phospholipid scramblase activity 5/3513 18/18639 0.277777777777778 1.47381155707373 0.241182884875999 0.588186413938908 GO:0035615 clathrin adaptor activity 5/3513 18/18639 0.277777777777778 1.47381155707373 0.241182884875999 0.588186413938908 GO:0005030 neurotrophin receptor activity 12/3513 51/18639 0.235294117647059 1.24840508363892 0.242960055942085 0.58928857204862 GO:0016597 amino acid binding 12/3513 51/18639 0.235294117647059 1.24840508363892 0.242960055942085 0.58928857204862 GO:0030544 Hsp70 protein binding 12/3513 51/18639 0.235294117647059 1.24840508363892 0.242960055942085 0.58928857204862 GO:0008378 galactosyltransferase activity 8/3513 32/18639 0.25 1.32643040136635 0.244925759488025 0.591903918762728 GO:0042910 xenobiotic transmembrane transporter activity 8/3513 32/18639 0.25 1.32643040136635 0.244925759488025 0.591903918762728 GO:0101005 deubiquitinase activity 25/3513 115/18639 0.217391304347826 1.15341774031857 0.245415754869893 0.592015582272039 GO:0030170 pyridoxal phosphate binding 13/3513 56/18639 0.232142857142857 1.23168537269733 0.246589830442093 0.593774068248651 GO:0008235 metalloexopeptidase activity 15/3513 66/18639 0.227272727272727 1.20584581942396 0.251958884283986 0.605035983707762 GO:0019213 deacetylase activity 9/3513 37/18639 0.243243243243243 1.29058093105915 0.252173918247013 0.605035983707762 GO:0098631 cell adhesion mediator activity 17/3513 76/18639 0.223684210526316 1.18680614859095 0.255522168082121 0.610209127880167 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 6/3513 23/18639 0.260869565217391 1.38410128838228 0.256159753832754 0.610209127880167 GO:0004602 glutathione peroxidase activity 6/3513 23/18639 0.260869565217391 1.38410128838228 0.256159753832754 0.610209127880167 GO:0140102 catalytic activity, acting on a rRNA 6/3513 23/18639 0.260869565217391 1.38410128838228 0.256159753832754 0.610209127880167 GO:0005178 integrin binding 34/3513 161/18639 0.211180124223602 1.12046294773804 0.257604397673974 0.61255662477198 GO:0004065 arylsulfatase activity 4/3513 14/18639 0.285714285714286 1.5159204587044 0.262769591050122 0.616053839122783 GO:0005161 platelet-derived growth factor receptor binding 4/3513 14/18639 0.285714285714286 1.5159204587044 0.262769591050122 0.616053839122783 GO:0005313 L-glutamate transmembrane transporter activity 4/3513 14/18639 0.285714285714286 1.5159204587044 0.262769591050122 0.616053839122783 GO:0008474 palmitoyl-(protein) hydrolase activity 4/3513 14/18639 0.285714285714286 1.5159204587044 0.262769591050122 0.616053839122783 GO:0061665 SUMO ligase activity 4/3513 14/18639 0.285714285714286 1.5159204587044 0.262769591050122 0.616053839122783 GO:0098599 palmitoyl hydrolase activity 4/3513 14/18639 0.285714285714286 1.5159204587044 0.262769591050122 0.616053839122783 GO:0098821 BMP receptor activity 4/3513 14/18639 0.285714285714286 1.5159204587044 0.262769591050122 0.616053839122783 GO:1901612 cardiolipin binding 4/3513 14/18639 0.285714285714286 1.5159204587044 0.262769591050122 0.616053839122783 GO:0031406 carboxylic acid binding 39/3513 187/18639 0.20855614973262 1.10654086958904 0.266458274824704 0.620407018847464 GO:0019789 SUMO transferase activity 7/3513 28/18639 0.25 1.32643040136635 0.266486673013191 0.620407018847464 GO:0045499 chemorepellent activity 7/3513 28/18639 0.25 1.32643040136635 0.266486673013191 0.620407018847464 GO:0051959 dynein light intermediate chain binding 7/3513 28/18639 0.25 1.32643040136635 0.266486673013191 0.620407018847464 GO:0016504 peptidase activator activity 13/3513 57/18639 0.228070175438596 1.21007685738685 0.268212196919317 0.622252296852814 GO:0070279 vitamin B6 binding 13/3513 57/18639 0.228070175438596 1.21007685738685 0.268212196919317 0.622252296852814 GO:0008514 organic anion transmembrane transporter activity 55/3513 269/18639 0.204460966542751 1.08481296766021 0.271976869709975 0.629890875335255 GO:0071889 14-3-3 protein binding 8/3513 33/18639 0.242424242424242 1.28623554071889 0.273892833041389 0.631659980211386 GO:0015171 amino acid transmembrane transporter activity 22/3513 102/18639 0.215686274509804 1.14437132666901 0.275976394331833 0.631659980211386 GO:0000146 microfilament motor activity 9/3513 38/18639 0.236842105263158 1.25661827497865 0.279337889064673 0.631659980211386 GO:0005520 insulin-like growth factor binding 5/3513 19/18639 0.263157894736842 1.39624252775406 0.280298963092171 0.631659980211386 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 5/3513 19/18639 0.263157894736842 1.39624252775406 0.280298963092171 0.631659980211386 GO:0042577 lipid phosphatase activity 5/3513 19/18639 0.263157894736842 1.39624252775406 0.280298963092171 0.631659980211386 GO:0050145 nucleoside monophosphate kinase activity 5/3513 19/18639 0.263157894736842 1.39624252775406 0.280298963092171 0.631659980211386 GO:0000182 rDNA binding 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0004090 carbonyl reductase (NADPH) activity 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0004955 prostaglandin receptor activity 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0005337 nucleoside transmembrane transporter activity 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0008140 cAMP response element binding protein binding 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0008190 eukaryotic initiation factor 4E binding 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0016868 intramolecular phosphotransferase activity 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0031957 very long-chain fatty acid-CoA ligase activity 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0031996 thioesterase binding 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0035374 chondroitin sulfate binding 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0043208 glycosphingolipid binding 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0043422 protein kinase B binding 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0051864 histone H3K36 demethylase activity 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0070097 delta-catenin binding 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0099122 RNA polymerase II C-terminal domain binding 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 3/3513 10/18639 0.3 1.59171648163962 0.287671241257774 0.631659980211386 GO:0038064 collagen receptor activity 12/3513 53/18639 0.226415094339623 1.20129545784123 0.288740480690156 0.631659980211386 GO:0051018 protein kinase A binding 12/3513 53/18639 0.226415094339623 1.20129545784123 0.288740480690156 0.631659980211386 GO:0043177 organic acid binding 39/3513 189/18639 0.206349206349206 1.09483144239763 0.290682889724837 0.631659980211386 GO:0005315 phosphate transmembrane transporter activity 6/3513 24/18639 0.25 1.32643040136635 0.291325176252128 0.631659980211386 GO:0015149 hexose transmembrane transporter activity 6/3513 24/18639 0.25 1.32643040136635 0.291325176252128 0.631659980211386 GO:0035035 histone acetyltransferase binding 6/3513 24/18639 0.25 1.32643040136635 0.291325176252128 0.631659980211386 GO:0048027 mRNA 5'-UTR binding 6/3513 24/18639 0.25 1.32643040136635 0.291325176252128 0.631659980211386 GO:0055056 D-glucose transmembrane transporter activity 6/3513 24/18639 0.25 1.32643040136635 0.291325176252128 0.631659980211386 GO:1901682 sulfur compound transmembrane transporter activity 14/3513 63/18639 0.222222222222222 1.17904924565898 0.291681070322499 0.631659980211386 GO:0001540 amyloid-beta binding 18/3513 83/18639 0.216867469879518 1.15063842046238 0.293571575546942 0.634723633354328 GO:0004467 long-chain fatty acid-CoA ligase activity 4/3513 15/18639 0.266666666666667 1.41485909479078 0.308961463969568 0.660025605956111 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 4/3513 15/18639 0.266666666666667 1.41485909479078 0.308961463969568 0.660025605956111 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 4/3513 15/18639 0.266666666666667 1.41485909479078 0.308961463969568 0.660025605956111 GO:0004865 protein serine/threonine phosphatase inhibitor activity 4/3513 15/18639 0.266666666666667 1.41485909479078 0.308961463969568 0.660025605956111 GO:0005402 carbohydrate:monoatomic cation symporter activity 4/3513 15/18639 0.266666666666667 1.41485909479078 0.308961463969568 0.660025605956111 GO:0034483 heparan sulfate sulfotransferase activity 4/3513 15/18639 0.266666666666667 1.41485909479078 0.308961463969568 0.660025605956111 GO:0120283 protein serine/threonine kinase binding 4/3513 15/18639 0.266666666666667 1.41485909479078 0.308961463969568 0.660025605956111 GO:0016790 thiolester hydrolase activity 10/3513 44/18639 0.227272727272727 1.20584581942396 0.309727158417186 0.660025605956111 GO:0019205 nucleobase-containing compound kinase activity 10/3513 44/18639 0.227272727272727 1.20584581942396 0.309727158417186 0.660025605956111 GO:0035254 glutamate receptor binding 11/3513 49/18639 0.224489795918367 1.1910803604106 0.311415242032853 0.662564486238957 GO:0008186 ATP-dependent activity, acting on RNA 17/3513 79/18639 0.215189873417722 1.14173756066977 0.313046275025392 0.663916901246221 GO:0015370 solute:sodium symporter activity 17/3513 79/18639 0.215189873417722 1.14173756066977 0.313046275025392 0.663916901246221 GO:0000339 RNA cap binding 5/3513 20/18639 0.25 1.32643040136635 0.320511355881477 0.677594530500618 GO:0016004 phospholipase activator activity 5/3513 20/18639 0.25 1.32643040136635 0.320511355881477 0.677594530500618 GO:0008106 alcohol dehydrogenase (NADP+) activity 7/3513 30/18639 0.233333333333333 1.23800170794193 0.331613731256106 0.697748765766003 GO:0035925 mRNA 3'-UTR AU-rich region binding 7/3513 30/18639 0.233333333333333 1.23800170794193 0.331613731256106 0.697748765766003 GO:0070566 adenylyltransferase activity 7/3513 30/18639 0.233333333333333 1.23800170794193 0.331613731256106 0.697748765766003 GO:0044325 transmembrane transporter binding 28/3513 136/18639 0.205882352941176 1.09235444818406 0.333808087252239 0.699203019038517 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 9/3513 40/18639 0.225 1.19378736122972 0.335778208859054 0.699203019038517 GO:0050997 quaternary ammonium group binding 9/3513 40/18639 0.225 1.19378736122972 0.335778208859054 0.699203019038517 GO:0004715 non-membrane spanning protein tyrosine kinase activity 10/3513 45/18639 0.222222222222222 1.17904924565898 0.336588776933476 0.699203019038517 GO:0032813 tumor necrosis factor receptor superfamily binding 11/3513 50/18639 0.22 1.16725875320239 0.336871481762998 0.699203019038517 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0004016 adenylate cyclase activity 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0004143 ATP-dependent diacylglycerol kinase activity 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0004954 prostanoid receptor activity 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0005225 volume-sensitive anion channel activity 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0005536 D-glucose binding 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0008046 axon guidance receptor activity 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0008432 JUN kinase binding 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0019215 intermediate filament binding 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0035252 UDP-xylosyltransferase activity 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0042285 xylosyltransferase activity 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0045294 alpha-catenin binding 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0070697 activin receptor binding 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0140031 phosphorylation-dependent protein binding 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 3/3513 11/18639 0.272727272727273 1.44701498330875 0.34436010757744 0.699203019038517 GO:0015631 tubulin binding 76/3513 385/18639 0.197402597402597 1.04736322601395 0.345394262576732 0.700237000421519 GO:0072341 modified amino acid binding 19/3513 91/18639 0.208791208791209 1.10778802751476 0.349698985224945 0.707888385872651 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 25/3513 122/18639 0.204918032786885 1.08723803390685 0.35552361910255 0.708458290799329 GO:0000062 fatty-acyl-CoA binding 4/3513 16/18639 0.25 1.32643040136635 0.355822379936695 0.708458290799329 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 4/3513 16/18639 0.25 1.32643040136635 0.355822379936695 0.708458290799329 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 4/3513 16/18639 0.25 1.32643040136635 0.355822379936695 0.708458290799329 GO:0005521 lamin binding 4/3513 16/18639 0.25 1.32643040136635 0.355822379936695 0.708458290799329 GO:0008296 3'-5'-DNA exonuclease activity 4/3513 16/18639 0.25 1.32643040136635 0.355822379936695 0.708458290799329 GO:0015378 sodium:chloride symporter activity 4/3513 16/18639 0.25 1.32643040136635 0.355822379936695 0.708458290799329 GO:0022858 alanine transmembrane transporter activity 4/3513 16/18639 0.25 1.32643040136635 0.355822379936695 0.708458290799329 GO:0097027 ubiquitin-protein transferase activator activity 4/3513 16/18639 0.25 1.32643040136635 0.355822379936695 0.708458290799329 GO:0140327 flippase activity 4/3513 16/18639 0.25 1.32643040136635 0.355822379936695 0.708458290799329 GO:0140328 floppase activity 4/3513 16/18639 0.25 1.32643040136635 0.355822379936695 0.708458290799329 GO:0009931 calcium-dependent protein serine/threonine kinase activity 5/3513 21/18639 0.238095238095238 1.26326704892034 0.361306341342511 0.711147450286507 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 5/3513 21/18639 0.238095238095238 1.26326704892034 0.361306341342511 0.711147450286507 GO:0005048 signal sequence binding 11/3513 51/18639 0.215686274509804 1.14437132666901 0.362697123863748 0.711147450286507 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 6/3513 26/18639 0.230769230769231 1.22439729356894 0.363949636006218 0.711147450286507 GO:0008143 poly(A) binding 6/3513 26/18639 0.230769230769231 1.22439729356894 0.363949636006218 0.711147450286507 GO:0043548 phosphatidylinositol 3-kinase binding 6/3513 26/18639 0.230769230769231 1.22439729356894 0.363949636006218 0.711147450286507 GO:0050750 low-density lipoprotein particle receptor binding 6/3513 26/18639 0.230769230769231 1.22439729356894 0.363949636006218 0.711147450286507 GO:0015175 neutral L-amino acid transmembrane transporter activity 9/3513 41/18639 0.219512195121951 1.16467059632168 0.364706005215497 0.711147450286507 GO:0140318 protein transporter activity 9/3513 41/18639 0.219512195121951 1.16467059632168 0.364706005215497 0.711147450286507 GO:0047499 calcium-independent phospholipase A2 activity 7/3513 31/18639 0.225806451612903 1.19806616897606 0.365030209361328 0.711147450286507 GO:0070325 lipoprotein particle receptor binding 7/3513 31/18639 0.225806451612903 1.19806616897606 0.365030209361328 0.711147450286507 GO:0004190 aspartic-type endopeptidase activity 8/3513 36/18639 0.222222222222222 1.17904924565898 0.365169417875755 0.711147450286507 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 8/3513 36/18639 0.222222222222222 1.17904924565898 0.365169417875755 0.711147450286507 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 8/3513 36/18639 0.222222222222222 1.17904924565898 0.365169417875755 0.711147450286507 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 8/3513 36/18639 0.222222222222222 1.17904924565898 0.365169417875755 0.711147450286507 GO:0052689 carboxylic ester hydrolase activity 19/3513 92/18639 0.206521739130435 1.09574685330264 0.368935390315903 0.717434126357747 GO:0005539 glycosaminoglycan binding 48/3513 242/18639 0.198347107438017 1.05237453331545 0.371649233650489 0.721659501731808 GO:0003724 RNA helicase activity 16/3513 77/18639 0.207792207792208 1.10248760633048 0.376131181608213 0.729300866664761 GO:0140767 enzyme-substrate adaptor activity 28/3513 139/18639 0.201438848920863 1.06877845289951 0.380666508576639 0.730759876048756 GO:0016500 protein-hormone receptor activity 14/3513 67/18639 0.208955223880597 1.10865824591815 0.38110695413116 0.730759876048756 GO:0015103 inorganic anion transmembrane transporter activity 33/3513 165/18639 0.2 1.06114432109308 0.382515306434997 0.730759876048756 GO:0015179 L-amino acid transmembrane transporter activity 13/3513 62/18639 0.209677419354839 1.1124900140492 0.383641183363413 0.730759876048756 GO:0019842 vitamin binding 30/3513 150/18639 0.2 1.06114432109308 0.390731751307737 0.730759876048756 GO:0048487 beta-tubulin binding 9/3513 42/18639 0.214285714285714 1.1369403440283 0.393875128135802 0.730759876048756 GO:0051879 Hsp90 protein binding 9/3513 42/18639 0.214285714285714 1.1369403440283 0.393875128135802 0.730759876048756 GO:0022829 wide pore channel activity 8/3513 37/18639 0.216216216216216 1.14718304983036 0.396340590187132 0.730759876048756 GO:0070001 aspartic-type peptidase activity 8/3513 37/18639 0.216216216216216 1.14718304983036 0.396340590187132 0.730759876048756 GO:0022884 macromolecule transmembrane transporter activity 7/3513 32/18639 0.21875 1.16062660119556 0.398659455325853 0.730759876048756 GO:0120015 sterol transfer activity 7/3513 32/18639 0.21875 1.16062660119556 0.398659455325853 0.730759876048756 GO:0000340 RNA 7-methylguanosine cap binding 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0000995 RNA polymerase III general transcription initiation factor activity 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0004875 complement receptor activity 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0005078 MAP-kinase scaffold activity 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0005247 voltage-gated chloride channel activity 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0005436 sodium:phosphate symporter activity 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0015132 prostaglandin transmembrane transporter activity 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0015166 polyol transmembrane transporter activity 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0016208 AMP binding 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0034452 dynactin binding 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0035197 siRNA binding 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0035497 cAMP response element binding 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0036009 protein-glutamine N-methyltransferase activity 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0070008 serine-type exopeptidase activity 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0070679 inositol 1,4,5 trisphosphate binding 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0097371 MDM2/MDM4 family protein binding 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0140829 bicarbonate:monoatomic anion antiporter activity 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0140900 chloride:bicarbonate antiporter activity 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0141221 histone deacetylase activity, hydrolytic mechanism 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:1990817 poly(A) RNA polymerase activity 3/3513 12/18639 0.25 1.32643040136635 0.400591140259591 0.730759876048756 GO:0035255 ionotropic glutamate receptor binding 6/3513 27/18639 0.222222222222222 1.17904924565898 0.400699277262409 0.730759876048756 GO:0030021 extracellular matrix structural constituent conferring compression resistance 5/3513 22/18639 0.227272727272727 1.20584581942396 0.402204955702557 0.730759876048756 GO:0031683 G-protein beta/gamma-subunit complex binding 5/3513 22/18639 0.227272727272727 1.20584581942396 0.402204955702557 0.730759876048756 GO:0004029 aldehyde dehydrogenase (NAD+) activity 4/3513 17/18639 0.235294117647059 1.24840508363892 0.402630066638558 0.730759876048756 GO:0004550 nucleoside diphosphate kinase activity 4/3513 17/18639 0.235294117647059 1.24840508363892 0.402630066638558 0.730759876048756 GO:0008429 phosphatidylethanolamine binding 4/3513 17/18639 0.235294117647059 1.24840508363892 0.402630066638558 0.730759876048756 GO:0008484 sulfuric ester hydrolase activity 4/3513 17/18639 0.235294117647059 1.24840508363892 0.402630066638558 0.730759876048756 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 4/3513 17/18639 0.235294117647059 1.24840508363892 0.402630066638558 0.730759876048756 GO:0016805 dipeptidase activity 4/3513 17/18639 0.235294117647059 1.24840508363892 0.402630066638558 0.730759876048756 GO:0032183 SUMO binding 4/3513 17/18639 0.235294117647059 1.24840508363892 0.402630066638558 0.730759876048756 GO:0032977 membrane insertase activity 4/3513 17/18639 0.235294117647059 1.24840508363892 0.402630066638558 0.730759876048756 GO:0051787 misfolded protein binding 4/3513 17/18639 0.235294117647059 1.24840508363892 0.402630066638558 0.730759876048756 GO:0070403 NAD+ binding 4/3513 17/18639 0.235294117647059 1.24840508363892 0.402630066638558 0.730759876048756 GO:1901567 fatty acid derivative binding 4/3513 17/18639 0.235294117647059 1.24840508363892 0.402630066638558 0.730759876048756 GO:1990226 histone methyltransferase binding 4/3513 17/18639 0.235294117647059 1.24840508363892 0.402630066638558 0.730759876048756 GO:0032934 sterol binding 14/3513 68/18639 0.205882352941176 1.09235444818406 0.404065874700951 0.732369397895473 GO:0004864 protein phosphatase inhibitor activity 11/3513 53/18639 0.207547169811321 1.10118750302112 0.414967445744747 0.750299829272282 GO:0004860 protein kinase inhibitor activity 17/3513 84/18639 0.202380952380952 1.07377699158229 0.41508341379531 0.750299829272282 GO:0000287 magnesium ion binding 45/3513 230/18639 0.195652173913043 1.03807596628671 0.416187557105339 0.751277674125199 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 10/3513 48/18639 0.208333333333333 1.10535866780529 0.418938405075329 0.754880713316268 GO:0031072 heat shock protein binding 26/3513 131/18639 0.198473282442748 1.05304398276413 0.419315298776128 0.754880713316268 GO:0003697 single-stranded DNA binding 24/3513 121/18639 0.198347107438017 1.05237453331545 0.426547817995127 0.766866292729784 GO:0019210 kinase inhibitor activity 18/3513 90/18639 0.2 1.06114432109308 0.43159358956954 0.77398943042923 GO:0019239 deaminase activity 7/3513 33/18639 0.212121212121212 1.12545609812903 0.432250469017823 0.77398943042923 GO:0140311 protein sequestering activity 7/3513 33/18639 0.212121212121212 1.12545609812903 0.432250469017823 0.77398943042923 GO:0004879 nuclear receptor activity 12/3513 59/18639 0.203389830508475 1.07912981806076 0.436196967424801 0.775747103089213 GO:0005242 inward rectifier potassium channel activity 6/3513 28/18639 0.214285714285714 1.1369403440283 0.437302714784923 0.775747103089213 GO:0016866 intramolecular transferase activity 6/3513 28/18639 0.214285714285714 1.1369403440283 0.437302714784923 0.775747103089213 GO:0046625 sphingolipid binding 6/3513 28/18639 0.214285714285714 1.1369403440283 0.437302714784923 0.775747103089213 GO:0050698 proteoglycan sulfotransferase activity 6/3513 28/18639 0.214285714285714 1.1369403440283 0.437302714784923 0.775747103089213 GO:0051019 mitogen-activated protein kinase binding 6/3513 28/18639 0.214285714285714 1.1369403440283 0.437302714784923 0.775747103089213 GO:0051537 2 iron, 2 sulfur cluster binding 6/3513 28/18639 0.214285714285714 1.1369403440283 0.437302714784923 0.775747103089213 GO:0019783 ubiquitin-like protein peptidase activity 25/3513 127/18639 0.196850393700787 1.04443338690264 0.439897767334299 0.779148955877416 GO:0048306 calcium-dependent protein binding 16/3513 80/18639 0.2 1.06114432109308 0.440388540278539 0.779148955877416 GO:0005283 amino acid:sodium symporter activity 5/3513 23/18639 0.217391304347826 1.15341774031857 0.442773067333058 0.781295333098279 GO:0016493 C-C chemokine receptor activity 5/3513 23/18639 0.217391304347826 1.15341774031857 0.442773067333058 0.781295333098279 GO:0001222 transcription corepressor binding 10/3513 49/18639 0.204081632653061 1.082800327646 0.446508446881093 0.784591021009803 GO:0000400 four-way junction DNA binding 4/3513 18/18639 0.222222222222222 1.17904924565898 0.448757832856432 0.784591021009803 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 4/3513 18/18639 0.222222222222222 1.17904924565898 0.448757832856432 0.784591021009803 GO:0008308 voltage-gated monoatomic anion channel activity 4/3513 18/18639 0.222222222222222 1.17904924565898 0.448757832856432 0.784591021009803 GO:0008409 5'-3' exonuclease activity 4/3513 18/18639 0.222222222222222 1.17904924565898 0.448757832856432 0.784591021009803 GO:0015172 acidic amino acid transmembrane transporter activity 4/3513 18/18639 0.222222222222222 1.17904924565898 0.448757832856432 0.784591021009803 GO:0015373 monoatomic anion:sodium symporter activity 4/3513 18/18639 0.222222222222222 1.17904924565898 0.448757832856432 0.784591021009803 GO:0004465 lipoprotein lipase activity 3/3513 13/18639 0.230769230769231 1.22439729356894 0.455353228908717 0.785823036693697 GO:0008035 high-density lipoprotein particle binding 3/3513 13/18639 0.230769230769231 1.22439729356894 0.455353228908717 0.785823036693697 GO:0015651 quaternary ammonium group transmembrane transporter activity 3/3513 13/18639 0.230769230769231 1.22439729356894 0.455353228908717 0.785823036693697 GO:0030955 potassium ion binding 3/3513 13/18639 0.230769230769231 1.22439729356894 0.455353228908717 0.785823036693697 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 3/3513 13/18639 0.230769230769231 1.22439729356894 0.455353228908717 0.785823036693697 GO:0045159 myosin II binding 3/3513 13/18639 0.230769230769231 1.22439729356894 0.455353228908717 0.785823036693697 GO:0071837 HMG box domain binding 3/3513 13/18639 0.230769230769231 1.22439729356894 0.455353228908717 0.785823036693697 GO:0089720 caspase binding 3/3513 13/18639 0.230769230769231 1.22439729356894 0.455353228908717 0.785823036693697 GO:0097157 pre-mRNA intronic binding 3/3513 13/18639 0.230769230769231 1.22439729356894 0.455353228908717 0.785823036693697 GO:0140333 glycerophospholipid flippase activity 3/3513 13/18639 0.230769230769231 1.22439729356894 0.455353228908717 0.785823036693697 GO:0008509 monoatomic anion transmembrane transporter activity 29/3513 149/18639 0.194630872483221 1.03265722522481 0.456574628574978 0.786912861135686 GO:0000217 DNA secondary structure binding 8/3513 39/18639 0.205128205128205 1.08835314983906 0.458580624706927 0.788333187318351 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 8/3513 39/18639 0.205128205128205 1.08835314983906 0.458580624706927 0.788333187318351 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 12/3513 60/18639 0.2 1.06114432109308 0.461154031253005 0.790719122996798 GO:0098531 ligand-modulated transcription factor activity 12/3513 60/18639 0.2 1.06114432109308 0.461154031253005 0.790719122996798 GO:0015101 organic cation transmembrane transporter activity 16/3513 81/18639 0.197530864197531 1.04804377391909 0.461843252840125 0.79088433798296 GO:0070851 growth factor receptor binding 27/3513 139/18639 0.194244604316547 1.03060779386738 0.464965255090203 0.792181390030371 GO:0008175 tRNA methyltransferase activity 7/3513 34/18639 0.205882352941176 1.09235444818406 0.465569872401657 0.792181390030371 GO:0015020 glucuronosyltransferase activity 7/3513 34/18639 0.205882352941176 1.09235444818406 0.465569872401657 0.792181390030371 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 7/3513 34/18639 0.205882352941176 1.09235444818406 0.465569872401657 0.792181390030371 GO:0051427 hormone receptor binding 7/3513 34/18639 0.205882352941176 1.09235444818406 0.465569872401657 0.792181390030371 GO:0140313 molecular sequestering activity 11/3513 55/18639 0.2 1.06114432109308 0.467275786733032 0.794071209556516 GO:0003785 actin monomer binding 6/3513 29/18639 0.206896551724138 1.09773550457905 0.47346653788515 0.801528377587297 GO:0005416 amino acid:monoatomic cation symporter activity 6/3513 29/18639 0.206896551724138 1.09773550457905 0.47346653788515 0.801528377587297 GO:0099604 ligand-gated calcium channel activity 6/3513 29/18639 0.206896551724138 1.09773550457905 0.47346653788515 0.801528377587297 GO:0015399 primary active transmembrane transporter activity 32/3513 166/18639 0.192771084337349 1.02278970707767 0.474957887049754 0.803033994073982 GO:0005540 hyaluronic acid binding 5/3513 24/18639 0.208333333333333 1.10535866780529 0.48262777551225 0.811885816561591 GO:0019957 C-C chemokine binding 5/3513 24/18639 0.208333333333333 1.10535866780529 0.48262777551225 0.811885816561591 GO:0050699 WW domain binding 5/3513 24/18639 0.208333333333333 1.10535866780529 0.48262777551225 0.811885816561591 GO:0060229 lipase activator activity 5/3513 24/18639 0.208333333333333 1.10535866780529 0.48262777551225 0.811885816561591 GO:0140375 immune receptor activity 30/3513 156/18639 0.192307692307692 1.02033107797412 0.48358239741387 0.812467151322547 GO:0015297 antiporter activity 26/3513 135/18639 0.192592592592593 1.02184267957112 0.486028499725442 0.815549708973257 GO:0046943 carboxylic acid transmembrane transporter activity 36/3513 188/18639 0.191489361702128 1.01598924359976 0.487392344909275 0.816810789081625 GO:0019212 phosphatase inhibitor activity 11/3513 56/18639 0.196428571428571 1.04219531535928 0.493166446950822 0.821158833293375 GO:0022821 solute:potassium antiporter activity 4/3513 19/18639 0.210526315789474 1.11699402220325 0.493680198126902 0.821158833293375 GO:0031420 alkali metal ion binding 4/3513 19/18639 0.210526315789474 1.11699402220325 0.493680198126902 0.821158833293375 GO:0097001 ceramide binding 4/3513 19/18639 0.210526315789474 1.11699402220325 0.493680198126902 0.821158833293375 GO:0120227 acyl-CoA binding 4/3513 19/18639 0.210526315789474 1.11699402220325 0.493680198126902 0.821158833293375 GO:1990380 K48-linked deubiquitinase activity 4/3513 19/18639 0.210526315789474 1.11699402220325 0.493680198126902 0.821158833293375 GO:0004623 phospholipase A2 activity 7/3513 35/18639 0.2 1.06114432109308 0.498404841568058 0.825928023169925 GO:0005343 organic acid:sodium symporter activity 7/3513 35/18639 0.2 1.06114432109308 0.498404841568058 0.825928023169925 GO:0140566 histone reader activity 7/3513 35/18639 0.2 1.06114432109308 0.498404841568058 0.825928023169925 GO:0005342 organic acid transmembrane transporter activity 36/3513 189/18639 0.19047619047619 1.01061363913627 0.501471728904261 0.829979263471816 GO:0008174 mRNA methyltransferase activity 3/3513 14/18639 0.214285714285714 1.1369403440283 0.507876039233788 0.831294932194272 GO:0008191 metalloendopeptidase inhibitor activity 3/3513 14/18639 0.214285714285714 1.1369403440283 0.507876039233788 0.831294932194272 GO:0008195 phosphatidate phosphatase activity 3/3513 14/18639 0.214285714285714 1.1369403440283 0.507876039233788 0.831294932194272 GO:0008331 high voltage-gated calcium channel activity 3/3513 14/18639 0.214285714285714 1.1369403440283 0.507876039233788 0.831294932194272 GO:0015386 potassium:proton antiporter activity 3/3513 14/18639 0.214285714285714 1.1369403440283 0.507876039233788 0.831294932194272 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 3/3513 14/18639 0.214285714285714 1.1369403440283 0.507876039233788 0.831294932194272 GO:0019763 immunoglobulin receptor activity 3/3513 14/18639 0.214285714285714 1.1369403440283 0.507876039233788 0.831294932194272 GO:0098847 sequence-specific single stranded DNA binding 3/3513 14/18639 0.214285714285714 1.1369403440283 0.507876039233788 0.831294932194272 GO:0033612 receptor serine/threonine kinase binding 6/3513 30/18639 0.2 1.06114432109308 0.508929739542411 0.831294932194272 GO:0048019 receptor antagonist activity 6/3513 30/18639 0.2 1.06114432109308 0.508929739542411 0.831294932194272 GO:0004180 carboxypeptidase activity 9/3513 46/18639 0.195652173913043 1.03807596628671 0.509744568616877 0.831294932194272 GO:0030291 protein serine/threonine kinase inhibitor activity 9/3513 46/18639 0.195652173913043 1.03807596628671 0.509744568616877 0.831294932194272 GO:0005126 cytokine receptor binding 52/3513 275/18639 0.189090909090909 1.00326372176073 0.514242142106442 0.836584167768285 GO:1901681 sulfur compound binding 52/3513 275/18639 0.189090909090909 1.00326372176073 0.514242142106442 0.836584167768285 GO:0015108 chloride transmembrane transporter activity 23/3513 121/18639 0.190082644628099 1.00852559442731 0.518838990330739 0.841114701501611 GO:0140828 metal cation:monoatomic cation antiporter activity 8/3513 41/18639 0.195121951219512 1.03526275228593 0.519481282839416 0.841114701501611 GO:0003707 nuclear steroid receptor activity 5/3513 25/18639 0.2 1.06114432109308 0.521440673269739 0.841114701501611 GO:0015662 P-type ion transporter activity 5/3513 25/18639 0.2 1.06114432109308 0.521440673269739 0.841114701501611 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 5/3513 25/18639 0.2 1.06114432109308 0.521440673269739 0.841114701501611 GO:0017025 TBP-class protein binding 5/3513 25/18639 0.2 1.06114432109308 0.521440673269739 0.841114701501611 GO:0140358 P-type transmembrane transporter activity 5/3513 25/18639 0.2 1.06114432109308 0.521440673269739 0.841114701501611 GO:0015081 sodium ion transmembrane transporter activity 31/3513 164/18639 0.189024390243902 1.002910791277 0.524614419514311 0.845212120328612 GO:0051117 ATPase binding 16/3513 84/18639 0.19047619047619 1.01061363913627 0.525461517410326 0.845555686640983 GO:0004033 aldo-keto reductase (NADPH) activity 7/3513 36/18639 0.194444444444444 1.03166808995161 0.530565116252407 0.852739596482785 GO:0016505 peptidase activator activity involved in apoptotic process 4/3513 20/18639 0.2 1.06114432109308 0.536972408688258 0.857869692443276 GO:0030742 GTP-dependent protein binding 4/3513 20/18639 0.2 1.06114432109308 0.536972408688258 0.857869692443276 GO:0042288 MHC class I protein binding 4/3513 20/18639 0.2 1.06114432109308 0.536972408688258 0.857869692443276 GO:0061608 nuclear import signal receptor activity 4/3513 20/18639 0.2 1.06114432109308 0.536972408688258 0.857869692443276 GO:0140664 ATP-dependent DNA damage sensor activity 4/3513 20/18639 0.2 1.06114432109308 0.536972408688258 0.857869692443276 GO:0005164 tumor necrosis factor receptor binding 6/3513 31/18639 0.193548387096774 1.02691385912234 0.543465626785872 0.865135019251018 GO:0005452 solute:inorganic anion antiporter activity 6/3513 31/18639 0.193548387096774 1.02691385912234 0.543465626785872 0.865135019251018 GO:0072349 modified amino acid transmembrane transporter activity 6/3513 31/18639 0.193548387096774 1.02691385912234 0.543465626785872 0.865135019251018 GO:0016859 cis-trans isomerase activity 8/3513 42/18639 0.19047619047619 1.01061363913627 0.549035672181442 0.870039686588106 GO:0019894 kinesin binding 8/3513 42/18639 0.19047619047619 1.01061363913627 0.549035672181442 0.870039686588106 GO:0017046 peptide hormone binding 10/3513 53/18639 0.188679245283019 1.00107954820102 0.554011606893783 0.870039686588106 GO:0000774 adenyl-nucleotide exchange factor activity 3/3513 15/18639 0.2 1.06114432109308 0.557604683049844 0.870039686588106 GO:0004953 icosanoid receptor activity 3/3513 15/18639 0.2 1.06114432109308 0.557604683049844 0.870039686588106 GO:0015556 C4-dicarboxylate transmembrane transporter activity 3/3513 15/18639 0.2 1.06114432109308 0.557604683049844 0.870039686588106 GO:0017081 chloride channel regulator activity 3/3513 15/18639 0.2 1.06114432109308 0.557604683049844 0.870039686588106 GO:0031005 filamin binding 3/3513 15/18639 0.2 1.06114432109308 0.557604683049844 0.870039686588106 GO:0051371 muscle alpha-actinin binding 3/3513 15/18639 0.2 1.06114432109308 0.557604683049844 0.870039686588106 GO:0061578 K63-linked deubiquitinase activity 3/3513 15/18639 0.2 1.06114432109308 0.557604683049844 0.870039686588106 GO:0140161 monocarboxylate:sodium symporter activity 3/3513 15/18639 0.2 1.06114432109308 0.557604683049844 0.870039686588106 GO:0141050 histone H3K deacetylase activity 3/3513 15/18639 0.2 1.06114432109308 0.557604683049844 0.870039686588106 GO:0141051 histone H4K deacetylase activity 3/3513 15/18639 0.2 1.06114432109308 0.557604683049844 0.870039686588106 GO:0051087 protein-folding chaperone binding 25/3513 134/18639 0.186567164179104 0.989873433855488 0.557711869596754 0.870039686588106 GO:0004529 DNA exonuclease activity 5/3513 26/18639 0.192307692307692 1.02033107797412 0.558938539284863 0.870039686588106 GO:0008157 protein phosphatase 1 binding 5/3513 26/18639 0.192307692307692 1.02033107797412 0.558938539284863 0.870039686588106 GO:0008198 ferrous iron binding 5/3513 26/18639 0.192307692307692 1.02033107797412 0.558938539284863 0.870039686588106 GO:0034237 protein kinase A regulatory subunit binding 5/3513 26/18639 0.192307692307692 1.02033107797412 0.558938539284863 0.870039686588106 GO:0051139 metal cation:proton antiporter activity 5/3513 26/18639 0.192307692307692 1.02033107797412 0.558938539284863 0.870039686588106 GO:0097110 scaffold protein binding 13/3513 70/18639 0.185714285714286 0.985348298157863 0.571952984985045 0.88801008252644 GO:0015106 bicarbonate transmembrane transporter activity 6/3513 32/18639 0.1875 0.994822801024765 0.576882435584338 0.88801008252644 GO:0047498 calcium-dependent phospholipase A2 activity 6/3513 32/18639 0.1875 0.994822801024765 0.576882435584338 0.88801008252644 GO:0008373 sialyltransferase activity 4/3513 21/18639 0.19047619047619 1.01061363913627 0.578305601004904 0.88801008252644 GO:0009975 cyclase activity 4/3513 21/18639 0.19047619047619 1.01061363913627 0.578305601004904 0.88801008252644 GO:0070182 DNA polymerase binding 4/3513 21/18639 0.19047619047619 1.01061363913627 0.578305601004904 0.88801008252644 GO:0140463 chromatin-protein adaptor activity 10/3513 54/18639 0.185185185185185 0.982541038049151 0.579656558159776 0.88801008252644 GO:0160215 deacylase activity 12/3513 65/18639 0.184615384615385 0.979517834855153 0.581896273123508 0.88801008252644 GO:0005201 extracellular matrix structural constituent 31/3513 168/18639 0.18452380952381 0.979031962913261 0.583647232481853 0.88801008252644 GO:0042277 peptide binding 46/3513 249/18639 0.184738955823293 0.980173469282767 0.586123500171513 0.88801008252644 GO:0001094 TFIID-class transcription factor complex binding 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:0005031 tumor necrosis factor receptor activity 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:0005381 iron ion transmembrane transporter activity 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:0015203 polyamine transmembrane transporter activity 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:0030957 Tat protein binding 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:0031434 mitogen-activated protein kinase kinase binding 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:0050308 sugar-phosphatase activity 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:0050815 phosphoserine residue binding 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:0070513 death domain binding 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:0140940 histone H2A methyltransferase activity 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:0141109 transporter activator activity 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:1905394 retromer complex binding 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:1990259 histone H2AQ104 methyltransferase activity 2/3513 10/18639 0.2 1.06114432109308 0.588456456486786 0.88801008252644 GO:0005109 frizzled binding 7/3513 38/18639 0.184210526315789 0.977369769427839 0.592219657267691 0.892679121802372 GO:0008320 protein transmembrane transporter activity 5/3513 27/18639 0.185185185185185 0.982541038049151 0.59490200792633 0.894700426802394 GO:0016405 CoA-ligase activity 5/3513 27/18639 0.185185185185185 0.982541038049151 0.59490200792633 0.894700426802394 GO:0005516 calmodulin binding 38/3513 207/18639 0.183574879227053 0.97399720293568 0.600097018587608 0.900516819124126 GO:0004708 MAP kinase kinase activity 3/3513 16/18639 0.1875 0.994822801024765 0.604169829922109 0.900516819124126 GO:0005159 insulin-like growth factor receptor binding 3/3513 16/18639 0.1875 0.994822801024765 0.604169829922109 0.900516819124126 GO:0015385 sodium:proton antiporter activity 3/3513 16/18639 0.1875 0.994822801024765 0.604169829922109 0.900516819124126 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/3513 16/18639 0.1875 0.994822801024765 0.604169829922109 0.900516819124126 GO:0017070 U6 snRNA binding 3/3513 16/18639 0.1875 0.994822801024765 0.604169829922109 0.900516819124126 GO:0055102 lipase inhibitor activity 3/3513 16/18639 0.1875 0.994822801024765 0.604169829922109 0.900516819124126 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 3/3513 16/18639 0.1875 0.994822801024765 0.604169829922109 0.900516819124126 GO:0030020 extracellular matrix structural constituent conferring tensile strength 8/3513 44/18639 0.181818181818182 0.964676655539166 0.605714660012923 0.901811781760312 GO:0019956 chemokine binding 6/3513 33/18639 0.181818181818182 0.964676655539166 0.609022872599119 0.90471771942898 GO:0030296 protein tyrosine kinase activator activity 6/3513 33/18639 0.181818181818182 0.964676655539166 0.609022872599119 0.90471771942898 GO:0008970 phospholipase A1 activity 4/3513 22/18639 0.181818181818182 0.964676655539166 0.617439077738759 0.915181921892783 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 4/3513 22/18639 0.181818181818182 0.964676655539166 0.617439077738759 0.915181921892783 GO:0016776 phosphotransferase activity, phosphate group as acceptor 7/3513 39/18639 0.179487179487179 0.952309006109177 0.621453195640358 0.920109392879287 GO:0004518 nuclease activity 38/3513 209/18639 0.181818181818182 0.964676655539166 0.625569544151153 0.923608699487095 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 12/3513 67/18639 0.17910447761194 0.950278496501268 0.626899245393023 0.923608699487095 GO:0051539 4 iron, 4 sulfur cluster binding 8/3513 45/18639 0.177777777777778 0.943239396527185 0.632637172540612 0.923608699487095 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 23/3513 128/18639 0.1796875 0.953371850982067 0.636054322210697 0.923608699487095 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 6/3513 34/18639 0.176470588235294 0.936303812729191 0.639762801212861 0.923608699487095 GO:0019825 oxygen binding 6/3513 34/18639 0.176470588235294 0.936303812729191 0.639762801212861 0.923608699487095 GO:0000099 sulfur amino acid transmembrane transporter activity 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0002162 dystroglycan binding 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0003953 NAD+ nucleosidase activity 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0015173 aromatic amino acid transmembrane transporter activity 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0015217 ADP transmembrane transporter activity 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0016594 glycine binding 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0019107 myristoyltransferase activity 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0019203 carbohydrate phosphatase activity 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0019206 nucleoside kinase activity 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0019864 IgG binding 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0032404 mismatch repair complex binding 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0034056 estrogen response element binding 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0048407 platelet-derived growth factor binding 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0097493 structural molecule activity conferring elasticity 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0099528 G protein-coupled neurotransmitter receptor activity 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0180030 inositol phosphate kinase activity 2/3513 11/18639 0.181818181818182 0.964676655539166 0.642700089577753 0.923608699487095 GO:0005200 structural constituent of cytoskeleton 20/3513 112/18639 0.178571428571429 0.947450286690253 0.643681862877684 0.923608699487095 GO:0004659 prenyltransferase activity 3/3513 17/18639 0.176470588235294 0.936303812729191 0.647356922054299 0.923608699487095 GO:0005092 GDP-dissociation inhibitor activity 3/3513 17/18639 0.176470588235294 0.936303812729191 0.647356922054299 0.923608699487095 GO:0008569 minus-end-directed microtubule motor activity 3/3513 17/18639 0.176470588235294 0.936303812729191 0.647356922054299 0.923608699487095 GO:0009881 photoreceptor activity 3/3513 17/18639 0.176470588235294 0.936303812729191 0.647356922054299 0.923608699487095 GO:0015278 intracellularly gated calcium channel activity 3/3513 17/18639 0.176470588235294 0.936303812729191 0.647356922054299 0.923608699487095 GO:0015347 sodium-independent organic anion transmembrane transporter activity 3/3513 17/18639 0.176470588235294 0.936303812729191 0.647356922054299 0.923608699487095 GO:0016018 cyclosporin A binding 3/3513 17/18639 0.176470588235294 0.936303812729191 0.647356922054299 0.923608699487095 GO:0036041 long-chain fatty acid binding 3/3513 17/18639 0.176470588235294 0.936303812729191 0.647356922054299 0.923608699487095 GO:0045125 bioactive lipid receptor activity 3/3513 17/18639 0.176470588235294 0.936303812729191 0.647356922054299 0.923608699487095 GO:0061791 GTPase motor activity 7/3513 40/18639 0.175 0.928501280956447 0.649489673482789 0.923687872522432 GO:0071949 FAD binding 7/3513 40/18639 0.175 0.928501280956447 0.649489673482789 0.923687872522432 GO:1990606 membrane scission GTPase motor activity 7/3513 40/18639 0.175 0.928501280956447 0.649489673482789 0.923687872522432 GO:0005158 insulin receptor binding 4/3513 23/18639 0.173913043478261 0.922734192254855 0.654210869403117 0.928669634759342 GO:0003924 GTPase activity 60/3513 331/18639 0.181268882175227 0.961762224555664 0.654384900055309 0.928669634759342 GO:0003684 damaged DNA binding 13/3513 74/18639 0.175675675675676 0.932086227987167 0.657278587136402 0.931784947120042 GO:0005507 copper ion binding 11/3513 63/18639 0.174603174603175 0.926395835874913 0.661080698687257 0.934929701900744 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 5/3513 29/18639 0.172413793103448 0.914779587149209 0.661599429231111 0.934929701900744 GO:0097472 cyclin-dependent protein kinase activity 5/3513 29/18639 0.172413793103448 0.914779587149209 0.661599429231111 0.934929701900744 GO:0000049 tRNA binding 14/3513 80/18639 0.175 0.928501280956447 0.665574997145755 0.939552429833266 GO:0004812 aminoacyl-tRNA ligase activity 7/3513 41/18639 0.170731707317073 0.905854908250193 0.676256106850543 0.951609331791798 GO:0016875 ligase activity, forming carbon-oxygen bonds 7/3513 41/18639 0.170731707317073 0.905854908250193 0.676256106850543 0.951609331791798 GO:0016877 ligase activity, forming carbon-sulfur bonds 7/3513 41/18639 0.170731707317073 0.905854908250193 0.676256106850543 0.951609331791798 GO:0099095 ligand-gated monoatomic anion channel activity 8/3513 47/18639 0.170212765957447 0.903101549866454 0.683272545429111 0.953419428309005 GO:0004970 glutamate-gated receptor activity 3/3513 18/18639 0.166666666666667 0.884286934244236 0.687076739893872 0.953419428309005 GO:0015280 ligand-gated sodium channel activity 3/3513 18/18639 0.166666666666667 0.884286934244236 0.687076739893872 0.953419428309005 GO:0031690 adrenergic receptor binding 3/3513 18/18639 0.166666666666667 0.884286934244236 0.687076739893872 0.953419428309005 GO:0098641 cadherin binding involved in cell-cell adhesion 3/3513 18/18639 0.166666666666667 0.884286934244236 0.687076739893872 0.953419428309005 GO:1990381 ubiquitin-specific protease binding 3/3513 18/18639 0.166666666666667 0.884286934244236 0.687076739893872 0.953419428309005 GO:0001091 RNA polymerase II general transcription initiation factor binding 4/3513 24/18639 0.166666666666667 0.884286934244236 0.688527488181291 0.953419428309005 GO:0004806 triacylglycerol lipase activity 4/3513 24/18639 0.166666666666667 0.884286934244236 0.688527488181291 0.953419428309005 GO:0030552 cAMP binding 4/3513 24/18639 0.166666666666667 0.884286934244236 0.688527488181291 0.953419428309005 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 4/3513 24/18639 0.166666666666667 0.884286934244236 0.688527488181291 0.953419428309005 GO:0140612 DNA damage sensor activity 4/3513 24/18639 0.166666666666667 0.884286934244236 0.688527488181291 0.953419428309005 GO:0004000 adenosine deaminase activity 2/3513 12/18639 0.166666666666667 0.884286934244236 0.691121879441385 0.953419428309005 GO:0004859 phospholipase inhibitor activity 2/3513 12/18639 0.166666666666667 0.884286934244236 0.691121879441385 0.953419428309005 GO:0005095 GTPase inhibitor activity 2/3513 12/18639 0.166666666666667 0.884286934244236 0.691121879441385 0.953419428309005 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 2/3513 12/18639 0.166666666666667 0.884286934244236 0.691121879441385 0.953419428309005 GO:0016273 arginine N-methyltransferase activity 2/3513 12/18639 0.166666666666667 0.884286934244236 0.691121879441385 0.953419428309005 GO:0016274 protein-arginine N-methyltransferase activity 2/3513 12/18639 0.166666666666667 0.884286934244236 0.691121879441385 0.953419428309005 GO:0016840 carbon-nitrogen lyase activity 2/3513 12/18639 0.166666666666667 0.884286934244236 0.691121879441385 0.953419428309005 GO:0043047 single-stranded telomeric DNA binding 2/3513 12/18639 0.166666666666667 0.884286934244236 0.691121879441385 0.953419428309005 GO:0005506 iron ion binding 27/3513 154/18639 0.175324675324675 0.930223917841339 0.693822651603798 0.954204594866287 GO:0051536 iron-sulfur cluster binding 13/3513 76/18639 0.171052631578947 0.907557643040137 0.696240810239008 0.954204594866287 GO:0070888 E-box binding 10/3513 59/18639 0.169491525423729 0.899274848383968 0.696552644183744 0.954204594866287 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 6/3513 36/18639 0.166666666666667 0.884286934244236 0.696698107496075 0.954204594866287 GO:0044390 ubiquitin-like protein conjugating enzyme binding 6/3513 36/18639 0.166666666666667 0.884286934244236 0.696698107496075 0.954204594866287 GO:0045505 dynein intermediate chain binding 6/3513 36/18639 0.166666666666667 0.884286934244236 0.696698107496075 0.954204594866287 GO:0055106 ubiquitin-protein transferase regulator activity 6/3513 36/18639 0.166666666666667 0.884286934244236 0.696698107496075 0.954204594866287 GO:0004519 endonuclease activity 22/3513 127/18639 0.173228346456693 0.919101380474324 0.70473374554749 0.964220324677283 GO:0051540 metal cluster binding 13/3513 77/18639 0.168831168831169 0.895771180143512 0.714688438794777 0.976838501385484 GO:0008139 nuclear localization sequence binding 4/3513 25/18639 0.16 0.848915456874466 0.720353548164444 0.981066229797446 GO:0015645 fatty acid ligase activity 4/3513 25/18639 0.16 0.848915456874466 0.720353548164444 0.981066229797446 GO:0120515 fatty acid-CoA ligase activity 4/3513 25/18639 0.16 0.848915456874466 0.720353548164444 0.981066229797446 GO:0016878 acid-thiol ligase activity 5/3513 31/18639 0.161290322580645 0.855761549268615 0.720723317242501 0.981066229797446 GO:0005346 purine ribonucleotide transmembrane transporter activity 3/3513 19/18639 0.157894736842105 0.837745516652434 0.723338591475179 0.982620856443878 GO:0008381 mechanosensitive monoatomic ion channel activity 3/3513 19/18639 0.157894736842105 0.837745516652434 0.723338591475179 0.982620856443878 GO:0008200 ion channel inhibitor activity 7/3513 43/18639 0.162790697674419 0.863722121819951 0.725788640051933 0.984946130039957 GO:0060590 ATPase regulator activity 8/3513 49/18639 0.163265306122449 0.866240262116802 0.729315090653917 0.985051510750324 GO:0002161 aminoacyl-tRNA editing activity 2/3513 13/18639 0.153846153846154 0.816264862379295 0.733988906810961 0.985051510750324 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/3513 13/18639 0.153846153846154 0.816264862379295 0.733988906810961 0.985051510750324 GO:0005035 death receptor activity 2/3513 13/18639 0.153846153846154 0.816264862379295 0.733988906810961 0.985051510750324 GO:0005542 folic acid binding 2/3513 13/18639 0.153846153846154 0.816264862379295 0.733988906810961 0.985051510750324 GO:0008417 fucosyltransferase activity 2/3513 13/18639 0.153846153846154 0.816264862379295 0.733988906810961 0.985051510750324 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 2/3513 13/18639 0.153846153846154 0.816264862379295 0.733988906810961 0.985051510750324 GO:0019855 calcium channel inhibitor activity 2/3513 13/18639 0.153846153846154 0.816264862379295 0.733988906810961 0.985051510750324 GO:0031994 insulin-like growth factor I binding 2/3513 13/18639 0.153846153846154 0.816264862379295 0.733988906810961 0.985051510750324 GO:0035673 oligopeptide transmembrane transporter activity 2/3513 13/18639 0.153846153846154 0.816264862379295 0.733988906810961 0.985051510750324 GO:0061459 L-arginine transmembrane transporter activity 2/3513 13/18639 0.153846153846154 0.816264862379295 0.733988906810961 0.985051510750324 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 10/3513 61/18639 0.163934426229508 0.869790427125478 0.737140099808818 0.988286324768807 GO:0033218 amide binding 43/3513 247/18639 0.174089068825911 0.923668133744991 0.743597083465662 0.995942278457021 GO:0031369 translation initiation factor binding 5/3513 32/18639 0.15625 0.829019000853971 0.747360517549569 0.998105898154216 GO:0140142 nucleocytoplasmic carrier activity 5/3513 32/18639 0.15625 0.829019000853971 0.747360517549569 0.998105898154216 GO:0016248 channel inhibitor activity 7/3513 44/18639 0.159090909090909 0.84409207359677 0.748505338978232 0.998105898154216 GO:0030547 signaling receptor inhibitor activity 7/3513 44/18639 0.159090909090909 0.84409207359677 0.748505338978232 0.998105898154216 GO:0030247 polysaccharide binding 4/3513 26/18639 0.153846153846154 0.816264862379295 0.749701731597095 0.998105898154216 GO:0097602 cullin family protein binding 4/3513 26/18639 0.153846153846154 0.816264862379295 0.749701731597095 0.998105898154216 GO:0003774 cytoskeletal motor activity 26/3513 153/18639 0.169934640522876 0.901625893739221 0.752170491974116 1 GO:0001972 retinoic acid binding 3/3513 20/18639 0.15 0.795858240819812 0.756226741378753 1 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 3/3513 20/18639 0.15 0.795858240819812 0.756226741378753 1 GO:0043024 ribosomal small subunit binding 3/3513 20/18639 0.15 0.795858240819812 0.756226741378753 1 GO:0140939 histone H4 methyltransferase activity 3/3513 20/18639 0.15 0.795858240819812 0.756226741378753 1 GO:0140223 general transcription initiation factor activity 11/3513 68/18639 0.161764705882353 0.858278495001758 0.759120492401752 1 GO:0005262 calcium channel activity 22/3513 131/18639 0.16793893129771 0.891037216185031 0.759209826852887 1 GO:0140098 catalytic activity, acting on RNA 68/3513 387/18639 0.175710594315245 0.932271496567566 0.760552132084661 1 GO:0004722 protein serine/threonine phosphatase activity 17/3513 103/18639 0.16504854368932 0.87570162420303 0.765387982733436 1 GO:0042605 peptide antigen binding 7/3513 45/18639 0.155555555555556 0.825334471961287 0.769849474900951 1 GO:0141110 transporter inhibitor activity 7/3513 45/18639 0.155555555555556 0.825334471961287 0.769849474900951 1 GO:0005347 ATP transmembrane transporter activity 2/3513 14/18639 0.142857142857143 0.757960229352202 0.77167438474049 1 GO:0008494 translation activator activity 2/3513 14/18639 0.142857142857143 0.757960229352202 0.77167438474049 1 GO:0016530 metallochaperone activity 2/3513 14/18639 0.142857142857143 0.757960229352202 0.77167438474049 1 GO:0019992 diacylglycerol binding 2/3513 14/18639 0.142857142857143 0.757960229352202 0.77167438474049 1 GO:0032036 myosin heavy chain binding 2/3513 14/18639 0.142857142857143 0.757960229352202 0.77167438474049 1 GO:0042043 neurexin family protein binding 2/3513 14/18639 0.142857142857143 0.757960229352202 0.77167438474049 1 GO:0043176 amine binding 2/3513 14/18639 0.142857142857143 0.757960229352202 0.77167438474049 1 GO:0044548 S100 protein binding 2/3513 14/18639 0.142857142857143 0.757960229352202 0.77167438474049 1 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 2/3513 14/18639 0.142857142857143 0.757960229352202 0.77167438474049 1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 2/3513 14/18639 0.142857142857143 0.757960229352202 0.77167438474049 1 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 22/3513 132/18639 0.166666666666667 0.884286934244236 0.771748701250826 1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 5/3513 33/18639 0.151515151515152 0.803897212949305 0.772063668433577 1 GO:0001671 ATPase activator activity 4/3513 27/18639 0.148148148148148 0.78603283043932 0.776623422670271 1 GO:0004364 glutathione transferase activity 4/3513 27/18639 0.148148148148148 0.78603283043932 0.776623422670271 1 GO:0005104 fibroblast growth factor receptor binding 4/3513 27/18639 0.148148148148148 0.78603283043932 0.776623422670271 1 GO:0005248 voltage-gated sodium channel activity 3/3513 21/18639 0.142857142857143 0.757960229352202 0.785880264774394 1 GO:0015174 basic amino acid transmembrane transporter activity 3/3513 21/18639 0.142857142857143 0.757960229352202 0.785880264774394 1 GO:0035613 RNA stem-loop binding 3/3513 21/18639 0.142857142857143 0.757960229352202 0.785880264774394 1 GO:0051428 peptide hormone receptor binding 3/3513 21/18639 0.142857142857143 0.757960229352202 0.785880264774394 1 GO:1904047 S-adenosyl-L-methionine binding 3/3513 21/18639 0.142857142857143 0.757960229352202 0.785880264774394 1 GO:0046982 protein heterodimerization activity 64/3513 369/18639 0.173441734417344 0.920233557587497 0.790609674167473 1 GO:0030332 cyclin binding 5/3513 34/18639 0.147058823529412 0.780253177274326 0.794874162781977 1 GO:0042562 hormone binding 15/3513 94/18639 0.159574468085106 0.8466577029998 0.800403796623936 1 GO:0004129 cytochrome-c oxidase activity 2/3513 15/18639 0.133333333333333 0.707429547395389 0.804608185000589 1 GO:0005523 tropomyosin binding 2/3513 15/18639 0.133333333333333 0.707429547395389 0.804608185000589 1 GO:0008020 G protein-coupled photoreceptor activity 2/3513 15/18639 0.133333333333333 0.707429547395389 0.804608185000589 1 GO:0008242 omega peptidase activity 2/3513 15/18639 0.133333333333333 0.707429547395389 0.804608185000589 1 GO:0010181 FMN binding 2/3513 15/18639 0.133333333333333 0.707429547395389 0.804608185000589 1 GO:0015250 water channel activity 2/3513 15/18639 0.133333333333333 0.707429547395389 0.804608185000589 1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/3513 15/18639 0.133333333333333 0.707429547395389 0.804608185000589 1 GO:0031386 protein tag activity 2/3513 15/18639 0.133333333333333 0.707429547395389 0.804608185000589 1 GO:0033130 acetylcholine receptor binding 2/3513 15/18639 0.133333333333333 0.707429547395389 0.804608185000589 1 GO:0045504 dynein heavy chain binding 2/3513 15/18639 0.133333333333333 0.707429547395389 0.804608185000589 1 GO:0048531 beta-1,3-galactosyltransferase activity 2/3513 15/18639 0.133333333333333 0.707429547395389 0.804608185000589 1 GO:0050700 CARD domain binding 2/3513 15/18639 0.133333333333333 0.707429547395389 0.804608185000589 1 GO:0140776 protein-containing complex destabilizing activity 2/3513 15/18639 0.133333333333333 0.707429547395389 0.804608185000589 1 GO:0141047 molecular tag activity 2/3513 15/18639 0.133333333333333 0.707429547395389 0.804608185000589 1 GO:0005246 calcium channel regulator activity 8/3513 53/18639 0.150943396226415 0.800863638560817 0.807102506934486 1 GO:0008146 sulfotransferase activity 8/3513 53/18639 0.150943396226415 0.800863638560817 0.807102506934486 1 GO:0016251 RNA polymerase II general transcription initiation factor activity 8/3513 53/18639 0.150943396226415 0.800863638560817 0.807102506934486 1 GO:0004857 enzyme inhibitor activity 72/3513 416/18639 0.173076923076923 0.918297970176706 0.808591464444608 1 GO:0004175 endopeptidase activity 70/3513 405/18639 0.172839506172839 0.917038302179207 0.8091757534724 1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 13/3513 83/18639 0.156626506024096 0.831016637000607 0.810081631822414 1 GO:0005254 chloride channel activity 13/3513 83/18639 0.156626506024096 0.831016637000607 0.810081631822414 1 GO:0008137 NADH dehydrogenase (ubiquinone) activity 6/3513 41/18639 0.146341463414634 0.776447064214451 0.811188849592255 1 GO:0017080 sodium channel regulator activity 6/3513 41/18639 0.146341463414634 0.776447064214451 0.811188849592255 1 GO:0042287 MHC protein binding 6/3513 41/18639 0.146341463414634 0.776447064214451 0.811188849592255 1 GO:0005243 gap junction channel activity 3/3513 22/18639 0.136363636363636 0.723507491654375 0.812476241674758 1 GO:0034062 5'-3' RNA polymerase activity 3/3513 22/18639 0.136363636363636 0.723507491654375 0.812476241674758 1 GO:0061133 endopeptidase activator activity 3/3513 22/18639 0.136363636363636 0.723507491654375 0.812476241674758 1 GO:0097747 RNA polymerase activity 3/3513 22/18639 0.136363636363636 0.723507491654375 0.812476241674758 1 GO:0005525 GTP binding 65/3513 378/18639 0.171957671957672 0.912359535331354 0.814216267844369 1 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 21/3513 130/18639 0.161538461538462 0.857078105498259 0.815013809804705 1 GO:0004181 metallocarboxypeptidase activity 4/3513 29/18639 0.137931034482759 0.731823669719367 0.823536330063639 1 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 8/3513 54/18639 0.148148148148148 0.78603283043932 0.823622162409676 1 GO:0038187 pattern recognition receptor activity 7/3513 48/18639 0.145833333333333 0.773751067463706 0.825827764935177 1 GO:0008307 structural constituent of muscle 6/3513 42/18639 0.142857142857143 0.757960229352202 0.829436958893571 1 GO:0003688 DNA replication origin binding 2/3513 16/18639 0.125 0.663215200683177 0.833242235726086 1 GO:0022841 potassium ion leak channel activity 2/3513 16/18639 0.125 0.663215200683177 0.833242235726086 1 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/3513 16/18639 0.125 0.663215200683177 0.833242235726086 1 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/3513 16/18639 0.125 0.663215200683177 0.833242235726086 1 GO:0033293 monocarboxylic acid binding 12/3513 79/18639 0.151898734177215 0.805932395766898 0.835677245890659 1 GO:0000295 adenine nucleotide transmembrane transporter activity 3/3513 23/18639 0.130434782608696 0.692050644191141 0.836216047515504 1 GO:0016849 phosphorus-oxygen lyase activity 3/3513 23/18639 0.130434782608696 0.692050644191141 0.836216047515504 1 GO:0031681 G-protein beta-subunit binding 3/3513 23/18639 0.130434782608696 0.692050644191141 0.836216047515504 1 GO:0005253 monoatomic anion channel activity 16/3513 103/18639 0.155339805825243 0.824189763955792 0.838634814727406 1 GO:0004540 RNA nuclease activity 19/3513 121/18639 0.15702479338843 0.833129838874734 0.842579583174376 1 GO:0031624 ubiquitin conjugating enzyme binding 4/3513 30/18639 0.133333333333333 0.707429547395389 0.843752170508991 1 GO:0046873 metal ion transmembrane transporter activity 77/3513 450/18639 0.171111111111111 0.907867919157415 0.844959054810905 1 GO:0003777 microtubule motor activity 10/3513 68/18639 0.147058823529412 0.780253177274326 0.849406053691073 1 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 19/3513 122/18639 0.155737704918033 0.826300905769204 0.852442306926882 1 GO:0030551 cyclic nucleotide binding 5/3513 37/18639 0.135135135135135 0.716989406143975 0.852613523358428 1 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/3513 24/18639 0.125 0.663215200683177 0.857314413134677 1 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/3513 24/18639 0.125 0.663215200683177 0.857314413134677 1 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/3513 24/18639 0.125 0.663215200683177 0.857314413134677 1 GO:0070840 dynein complex binding 3/3513 24/18639 0.125 0.663215200683177 0.857314413134677 1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/3513 17/18639 0.117647058823529 0.624202541819461 0.858026944215658 1 GO:0045236 CXCR chemokine receptor binding 2/3513 17/18639 0.117647058823529 0.624202541819461 0.858026944215658 1 GO:0048038 quinone binding 2/3513 17/18639 0.117647058823529 0.624202541819461 0.858026944215658 1 GO:0033192 calmodulin-dependent protein phosphatase activity 12/3513 81/18639 0.148148148148148 0.78603283043932 0.859644271670965 1 GO:0140791 histone H2AXS140 phosphatase activity 12/3513 81/18639 0.148148148148148 0.78603283043932 0.859644271670965 1 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 12/3513 81/18639 0.148148148148148 0.78603283043932 0.859644271670965 1 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 12/3513 81/18639 0.148148148148148 0.78603283043932 0.859644271670965 1 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 12/3513 81/18639 0.148148148148148 0.78603283043932 0.859644271670965 1 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 12/3513 81/18639 0.148148148148148 0.78603283043932 0.859644271670965 1 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 12/3513 81/18639 0.148148148148148 0.78603283043932 0.859644271670965 1 GO:1990439 MAP kinase serine/threonine phosphatase activity 12/3513 81/18639 0.148148148148148 0.78603283043932 0.859644271670965 1 GO:0003954 NADH dehydrogenase activity 6/3513 44/18639 0.136363636363636 0.723507491654375 0.861677339971379 1 GO:0005501 retinoid binding 5/3513 38/18639 0.131578947368421 0.698121263877028 0.868574166622127 1 GO:0019840 isoprenoid binding 5/3513 38/18639 0.131578947368421 0.698121263877028 0.868574166622127 1 GO:0016651 oxidoreductase activity, acting on NAD(P)H 13/3513 88/18639 0.147727272727273 0.783799782625573 0.869802276333308 1 GO:0005272 sodium channel activity 7/3513 51/18639 0.137254901960784 0.728236298789371 0.870499641093803 1 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 12/3513 82/18639 0.146341463414634 0.776447064214451 0.870551198873868 1 GO:0033549 MAP kinase phosphatase activity 12/3513 82/18639 0.146341463414634 0.776447064214451 0.870551198873868 1 GO:0017022 myosin binding 11/3513 76/18639 0.144736842105263 0.767933390264731 0.871719824052687 1 GO:0016782 transferase activity, transferring sulphur-containing groups 10/3513 70/18639 0.142857142857143 0.757960229352202 0.873407282016594 1 GO:0019001 guanyl nucleotide binding 67/3513 400/18639 0.1675 0.888708368915457 0.875676070809869 1 GO:0032561 guanyl ribonucleotide binding 67/3513 400/18639 0.1675 0.888708368915457 0.875676070809869 1 GO:0047617 fatty acyl-CoA hydrolase activity 3/3513 25/18639 0.12 0.63668659265585 0.875990894721528 1 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0008401 retinoic acid 4-hydroxylase activity 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0015187 glycine transmembrane transporter activity 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0015279 store-operated calcium channel activity 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0016427 tRNA (cytidine) methyltransferase activity 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0016783 sulfurtransferase activity 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0031419 cobalamin binding 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0032052 bile acid binding 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0032395 MHC class II receptor activity 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0035256 G protein-coupled glutamate receptor binding 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0043121 neurotrophin binding 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0043295 glutathione binding 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0047429 nucleoside triphosphate diphosphatase activity 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0051378 serotonin binding 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0097177 mitochondrial ribosome binding 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0098505 G-rich strand telomeric DNA binding 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0140135 mechanosensitive monoatomic cation channel activity 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:1990757 ubiquitin ligase activator activity 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:1990763 arrestin family protein binding 1/3513 10/18639 0.1 0.530572160546541 0.876185568346583 1 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 8/3513 58/18639 0.137931034482759 0.731823669719367 0.878899387054 1 GO:0004867 serine-type endopeptidase inhibitor activity 14/3513 95/18639 0.147368421052632 0.781895815542271 0.87907065382379 1 GO:0000900 mRNA regulatory element binding translation repressor activity 2/3513 18/18639 0.111111111111111 0.58952462282949 0.879395719755882 1 GO:0005372 water transmembrane transporter activity 2/3513 18/18639 0.111111111111111 0.58952462282949 0.879395719755882 1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/3513 18/18639 0.111111111111111 0.58952462282949 0.879395719755882 1 GO:0050811 GABA receptor binding 2/3513 18/18639 0.111111111111111 0.58952462282949 0.879395719755882 1 GO:0070064 proline-rich region binding 2/3513 18/18639 0.111111111111111 0.58952462282949 0.879395719755882 1 GO:0070628 proteasome binding 2/3513 18/18639 0.111111111111111 0.58952462282949 0.879395719755882 1 GO:0099602 neurotransmitter receptor regulator activity 2/3513 18/18639 0.111111111111111 0.58952462282949 0.879395719755882 1 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 7/3513 52/18639 0.134615384615385 0.714231754581883 0.883110098052928 1 GO:0005496 steroid binding 16/3513 108/18639 0.148148148148148 0.78603283043932 0.88719018918351 1 GO:0015459 potassium channel regulator activity 8/3513 59/18639 0.135593220338983 0.719419878707175 0.890231542223031 1 GO:0017018 myosin phosphatase activity 12/3513 84/18639 0.142857142857143 0.757960229352202 0.890330171591339 1 GO:0180051 translation factor activity 12/3513 84/18639 0.142857142857143 0.757960229352202 0.890330171591339 1 GO:0005112 Notch binding 3/3513 26/18639 0.115384615384615 0.612198646784471 0.892463394259497 1 GO:0005227 calcium-activated cation channel activity 3/3513 26/18639 0.115384615384615 0.612198646784471 0.892463394259497 1 GO:0008066 glutamate receptor activity 3/3513 26/18639 0.115384615384615 0.612198646784471 0.892463394259497 1 GO:0015216 purine nucleotide transmembrane transporter activity 3/3513 26/18639 0.115384615384615 0.612198646784471 0.892463394259497 1 GO:0016289 acyl-CoA hydrolase activity 3/3513 26/18639 0.115384615384615 0.612198646784471 0.892463394259497 1 GO:0019865 immunoglobulin binding 3/3513 26/18639 0.115384615384615 0.612198646784471 0.892463394259497 1 GO:0030507 spectrin binding 3/3513 26/18639 0.115384615384615 0.612198646784471 0.892463394259497 1 GO:0008301 DNA binding, bending 2/3513 19/18639 0.105263157894737 0.558497011101623 0.897755381906553 1 GO:0008574 plus-end-directed microtubule motor activity 2/3513 19/18639 0.105263157894737 0.558497011101623 0.897755381906553 1 GO:0016918 retinal binding 2/3513 19/18639 0.105263157894737 0.558497011101623 0.897755381906553 1 GO:0022840 leak channel activity 2/3513 19/18639 0.105263157894737 0.558497011101623 0.897755381906553 1 GO:0022842 narrow pore channel activity 2/3513 19/18639 0.105263157894737 0.558497011101623 0.897755381906553 1 GO:0034987 immunoglobulin receptor binding 2/3513 19/18639 0.105263157894737 0.558497011101623 0.897755381906553 1 GO:0042834 peptidoglycan binding 2/3513 19/18639 0.105263157894737 0.558497011101623 0.897755381906553 1 GO:0001851 complement component C3b binding 1/3513 11/18639 0.0909090909090909 0.482338327769583 0.899534116223466 1 GO:0008503 benzodiazepine receptor activity 1/3513 11/18639 0.0909090909090909 0.482338327769583 0.899534116223466 1 GO:0034511 U3 snoRNA binding 1/3513 11/18639 0.0909090909090909 0.482338327769583 0.899534116223466 1 GO:0042608 T cell receptor binding 1/3513 11/18639 0.0909090909090909 0.482338327769583 0.899534116223466 1 GO:0050786 RAGE receptor binding 1/3513 11/18639 0.0909090909090909 0.482338327769583 0.899534116223466 1 GO:0050998 nitric-oxide synthase binding 1/3513 11/18639 0.0909090909090909 0.482338327769583 0.899534116223466 1 GO:0070990 snRNP binding 1/3513 11/18639 0.0909090909090909 0.482338327769583 0.899534116223466 1 GO:1900750 oligopeptide binding 1/3513 11/18639 0.0909090909090909 0.482338327769583 0.899534116223466 1 GO:0005504 fatty acid binding 6/3513 47/18639 0.127659574468085 0.67732616239984 0.900439671437293 1 GO:0009055 electron transfer activity 17/3513 116/18639 0.146551724137931 0.777562649076828 0.902494340378767 1 GO:0017069 snRNA binding 7/3513 54/18639 0.12962962962963 0.687778726634406 0.905259027155564 1 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/3513 27/18639 0.111111111111111 0.58952462282949 0.90694339070815 1 GO:0001530 lipopolysaccharide binding 5/3513 41/18639 0.121951219512195 0.647039220178709 0.907932959280358 1 GO:0015085 calcium ion transmembrane transporter activity 22/3513 147/18639 0.149659863945578 0.794053573607069 0.9086619734424 1 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 2/3513 20/18639 0.1 0.530572160546541 0.913480786409641 1 GO:0015464 acetylcholine receptor activity 2/3513 20/18639 0.1 0.530572160546541 0.913480786409641 1 GO:0020037 heme binding 21/3513 142/18639 0.147887323943662 0.78464896982235 0.914739959381313 1 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 9/3513 68/18639 0.132352941176471 0.702227859546893 0.915210888722586 1 GO:0043022 ribosome binding 16/3513 112/18639 0.142857142857143 0.757960229352202 0.916951047138158 1 GO:0003720 telomerase activity 1/3513 12/18639 0.0833333333333333 0.442143467122118 0.918480683203655 1 GO:0004032 aldose reductase (NADPH) activity 1/3513 12/18639 0.0833333333333333 0.442143467122118 0.918480683203655 1 GO:0004126 cytidine deaminase activity 1/3513 12/18639 0.0833333333333333 0.442143467122118 0.918480683203655 1 GO:0004300 enoyl-CoA hydratase activity 1/3513 12/18639 0.0833333333333333 0.442143467122118 0.918480683203655 1 GO:0005049 nuclear export signal receptor activity 1/3513 12/18639 0.0833333333333333 0.442143467122118 0.918480683203655 1 GO:0015269 calcium-activated potassium channel activity 1/3513 12/18639 0.0833333333333333 0.442143467122118 0.918480683203655 1 GO:0015368 calcium:monoatomic cation antiporter activity 1/3513 12/18639 0.0833333333333333 0.442143467122118 0.918480683203655 1 GO:0016423 tRNA (guanine) methyltransferase activity 1/3513 12/18639 0.0833333333333333 0.442143467122118 0.918480683203655 1 GO:0042301 phosphate ion binding 1/3513 12/18639 0.0833333333333333 0.442143467122118 0.918480683203655 1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/3513 12/18639 0.0833333333333333 0.442143467122118 0.918480683203655 1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/3513 12/18639 0.0833333333333333 0.442143467122118 0.918480683203655 1 GO:1990459 transferrin receptor binding 1/3513 12/18639 0.0833333333333333 0.442143467122118 0.918480683203655 1 GO:0042056 chemoattractant activity 5/3513 42/18639 0.119047619047619 0.631633524460168 0.918540526900194 1 GO:0061134 peptidase regulator activity 35/3513 226/18639 0.154867256637168 0.82168254951898 0.919773089068895 1 GO:0019003 GDP binding 10/3513 75/18639 0.133333333333333 0.707429547395389 0.920050598513048 1 GO:0016874 ligase activity 25/3513 167/18639 0.149700598802395 0.794269701416978 0.920467827655038 1 GO:0015276 ligand-gated monoatomic ion channel activity 28/3513 186/18639 0.150537634408602 0.798710779317374 0.926003402067939 1 GO:0005179 hormone activity 19/3513 132/18639 0.143939393939394 0.76370235230184 0.926852054268413 1 GO:0015125 bile acid transmembrane transporter activity 2/3513 21/18639 0.0952380952380952 0.505306819568135 0.926912420265983 1 GO:0005245 voltage-gated calcium channel activity 5/3513 43/18639 0.116279069767442 0.616944372728537 0.928053123284246 1 GO:0048020 CCR chemokine receptor binding 6/3513 50/18639 0.12 0.63668659265585 0.929474927652505 1 GO:0106222 lncRNA binding 3/3513 29/18639 0.103448275862069 0.548867752289526 0.930720600914921 1 GO:0008135 translation factor activity, RNA binding 11/3513 83/18639 0.132530120481928 0.703167923615898 0.931420301886279 1 GO:0051082 unfolded protein binding 17/3513 121/18639 0.140495867768595 0.745431961098447 0.933702349003474 1 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/3513 13/18639 0.0769230769230769 0.408132431189647 0.933854997903046 1 GO:0003964 RNA-directed DNA polymerase activity 1/3513 13/18639 0.0769230769230769 0.408132431189647 0.933854997903046 1 GO:0009982 pseudouridine synthase activity 1/3513 13/18639 0.0769230769230769 0.408132431189647 0.933854997903046 1 GO:0031432 titin binding 1/3513 13/18639 0.0769230769230769 0.408132431189647 0.933854997903046 1 GO:0032396 inhibitory MHC class I receptor activity 1/3513 13/18639 0.0769230769230769 0.408132431189647 0.933854997903046 1 GO:0035325 Toll-like receptor binding 1/3513 13/18639 0.0769230769230769 0.408132431189647 0.933854997903046 1 GO:0070700 BMP receptor binding 1/3513 13/18639 0.0769230769230769 0.408132431189647 0.933854997903046 1 GO:0022834 ligand-gated channel activity 28/3513 188/18639 0.148936170212766 0.790213856133147 0.93495385664588 1 GO:0046906 tetrapyrrole binding 22/3513 152/18639 0.144736842105263 0.767933390264731 0.935632490495517 1 GO:0023023 MHC protein complex binding 4/3513 37/18639 0.108108108108108 0.57359152491518 0.937224491153051 1 GO:0008093 cytoskeletal anchor activity 2/3513 22/18639 0.0909090909090909 0.482338327769583 0.938356038125106 1 GO:0033691 sialic acid binding 2/3513 22/18639 0.0909090909090909 0.482338327769583 0.938356038125106 1 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 3/3513 30/18639 0.1 0.530572160546541 0.940383759848914 1 GO:0015215 nucleotide transmembrane transporter activity 3/3513 30/18639 0.1 0.530572160546541 0.940383759848914 1 GO:0022839 monoatomic ion-gated channel activity 3/3513 30/18639 0.1 0.530572160546541 0.940383759848914 1 GO:0019843 rRNA binding 8/3513 65/18639 0.123076923076923 0.653011889903436 0.941068354023865 1 GO:0008009 chemokine activity 5/3513 45/18639 0.111111111111111 0.58952462282949 0.94415760600174 1 GO:0099094 ligand-gated monoatomic cation channel activity 19/3513 136/18639 0.139705882352941 0.741240518410609 0.946195677806242 1 GO:0008392 arachidonate epoxygenase activity 1/3513 14/18639 0.0714285714285714 0.378980114676101 0.946330429684781 1 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/3513 14/18639 0.0714285714285714 0.378980114676101 0.946330429684781 1 GO:0030983 mismatched DNA binding 1/3513 14/18639 0.0714285714285714 0.378980114676101 0.946330429684781 1 GO:0034236 protein kinase A catalytic subunit binding 1/3513 14/18639 0.0714285714285714 0.378980114676101 0.946330429684781 1 GO:0071933 Arp2/3 complex binding 1/3513 14/18639 0.0714285714285714 0.378980114676101 0.946330429684781 1 GO:1901474 azole transmembrane transporter activity 1/3513 14/18639 0.0714285714285714 0.378980114676101 0.946330429684781 1 GO:1990825 sequence-specific mRNA binding 1/3513 14/18639 0.0714285714285714 0.378980114676101 0.946330429684781 1 GO:0015078 proton transmembrane transporter activity 27/3513 185/18639 0.145945945945946 0.774348558635493 0.946794512310103 1 GO:0004022 alcohol dehydrogenase (NAD+) activity 2/3513 23/18639 0.0869565217391304 0.461367096127427 0.948083656278401 1 GO:0005212 structural constituent of eye lens 2/3513 23/18639 0.0869565217391304 0.461367096127427 0.948083656278401 1 GO:0043274 phospholipase binding 2/3513 23/18639 0.0869565217391304 0.461367096127427 0.948083656278401 1 GO:0005310 dicarboxylic acid transmembrane transporter activity 3/3513 31/18639 0.0967741935483871 0.513456929561169 0.94878430548031 1 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 9/3513 73/18639 0.123287671232877 0.654130060947791 0.949072849859842 1 GO:0022853 active monoatomic ion transmembrane transporter activity 16/3513 118/18639 0.135593220338983 0.719419878707175 0.94914931312763 1 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 4/3513 39/18639 0.102564102564103 0.54417657491953 0.9524155874207 1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/3513 24/18639 0.0833333333333333 0.442143467122118 0.956335405655103 1 GO:0050661 NADP binding 6/3513 54/18639 0.111111111111111 0.58952462282949 0.956448410202106 1 GO:0004089 carbonate dehydratase activity 1/3513 15/18639 0.0666666666666667 0.353714773697694 0.956453447162224 1 GO:0016846 carbon-sulfur lyase activity 1/3513 15/18639 0.0666666666666667 0.353714773697694 0.956453447162224 1 GO:0030553 cGMP binding 1/3513 15/18639 0.0666666666666667 0.353714773697694 0.956453447162224 1 GO:0016836 hydro-lyase activity 7/3513 61/18639 0.114754098360656 0.608853298987834 0.956780465878622 1 GO:0071855 neuropeptide receptor binding 4/3513 40/18639 0.1 0.530572160546541 0.958668997453748 1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/3513 25/18639 0.08 0.424457728437233 0.963321884866719 1 GO:0008391 arachidonate monooxygenase activity 1/3513 16/18639 0.0625 0.331607600341588 0.964667527924633 1 GO:0016722 oxidoreductase activity, acting on metal ions 1/3513 16/18639 0.0625 0.331607600341588 0.964667527924633 1 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/3513 16/18639 0.0625 0.331607600341588 0.964667527924633 1 GO:0099106 ion channel regulator activity 22/3513 160/18639 0.1375 0.729536720751494 0.964766176112511 1 GO:0016831 carboxy-lyase activity 3/3513 34/18639 0.0882352941176471 0.468151906364595 0.967822262356633 1 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/3513 26/18639 0.0769230769230769 0.408132431189647 0.969226759083987 1 GO:0016247 channel regulator activity 23/3513 168/18639 0.136904761904762 0.726378553129194 0.969347003151571 1 GO:0030548 acetylcholine receptor regulator activity 1/3513 17/18639 0.0588235294117647 0.31210127090973 0.971332564406444 1 GO:0070492 oligosaccharide binding 1/3513 17/18639 0.0588235294117647 0.31210127090973 0.971332564406444 1 GO:0001664 G protein-coupled receptor binding 44/3513 297/18639 0.148148148148148 0.78603283043932 0.971849565143681 1 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4/3513 43/18639 0.0930232558139535 0.493555498182829 0.973150494384423 1 GO:0042379 chemokine receptor binding 8/3513 72/18639 0.111111111111111 0.58952462282949 0.973213152384567 1 GO:0141108 transporter regulator activity 23/3513 170/18639 0.135294117647059 0.717832923092379 0.973836269417754 1 GO:0008395 steroid hydroxylase activity 2/3513 27/18639 0.0740740740740741 0.39301641521966 0.974209428554054 1 GO:0023026 MHC class II protein complex binding 2/3513 27/18639 0.0740740740740741 0.39301641521966 0.974209428554054 1 GO:0016830 carbon-carbon lyase activity 5/3513 51/18639 0.0980392156862745 0.52016878484955 0.97481761861774 1 GO:0140101 catalytic activity, acting on a tRNA 18/3513 139/18639 0.129496402877698 0.687071862578255 0.975225966912443 1 GO:0004521 RNA endonuclease activity 8/3513 73/18639 0.10958904109589 0.581448943064703 0.976184266541457 1 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/3513 36/18639 0.0833333333333333 0.442143467122118 0.976557157262984 1 GO:0022851 GABA-gated chloride ion channel activity 1/3513 18/18639 0.0555555555555556 0.294762311414745 0.976740614091771 1 GO:0032393 MHC class I receptor activity 1/3513 18/18639 0.0555555555555556 0.294762311414745 0.976740614091771 1 GO:0036002 pre-mRNA binding 6/3513 59/18639 0.101694915254237 0.539564909030381 0.976901404652052 1 GO:0004866 endopeptidase inhibitor activity 21/3513 161/18639 0.130434782608696 0.692050644191141 0.980624620207888 1 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 5/3513 53/18639 0.0943396226415094 0.500539774100511 0.980895183215401 1 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/3513 19/18639 0.0526315789473684 0.279248505550811 0.981128682546505 1 GO:0004890 GABA-A receptor activity 1/3513 19/18639 0.0526315789473684 0.279248505550811 0.981128682546505 1 GO:0030506 ankyrin binding 1/3513 19/18639 0.0526315789473684 0.279248505550811 0.981128682546505 1 GO:0070003 threonine-type peptidase activity 1/3513 19/18639 0.0526315789473684 0.279248505550811 0.981128682546505 1 GO:0099589 serotonin receptor activity 1/3513 19/18639 0.0526315789473684 0.279248505550811 0.981128682546505 1 GO:0008236 serine-type peptidase activity 26/3513 194/18639 0.134020618556701 0.711076091454128 0.982690887049317 1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 4/3513 46/18639 0.0869565217391304 0.461367096127427 0.982763749345893 1 GO:0030414 peptidase inhibitor activity 22/3513 169/18639 0.130177514792899 0.69068565278248 0.983130635935991 1 GO:0016408 C-acyltransferase activity 1/3513 20/18639 0.05 0.265286080273271 0.984689098132656 1 GO:0043021 ribonucleoprotein complex binding 23/3513 177/18639 0.129943502824859 0.689444050427709 0.985301965981816 1 GO:0061135 endopeptidase regulator activity 24/3513 184/18639 0.130434782608696 0.692050644191141 0.986059674076755 1 GO:0022824 transmitter-gated monoatomic ion channel activity 6/3513 63/18639 0.0952380952380952 0.505306819568135 0.986398524157853 1 GO:0022835 transmitter-gated channel activity 6/3513 63/18639 0.0952380952380952 0.505306819568135 0.986398524157853 1 GO:0004497 monooxygenase activity 12/3513 106/18639 0.113207547169811 0.600647728920613 0.986997774314186 1 GO:0008188 neuropeptide receptor activity 4/3513 48/18639 0.0833333333333333 0.442143467122118 0.987249335532664 1 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/3513 48/18639 0.0833333333333333 0.442143467122118 0.987249335532664 1 GO:0017171 serine hydrolase activity 26/3513 198/18639 0.131313131313131 0.696710917889398 0.987478493049969 1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 5/3513 56/18639 0.0892857142857143 0.473725143345126 0.987487458363861 1 GO:0001846 opsonin binding 1/3513 21/18639 0.0476190476190476 0.252653409784067 0.98757793202599 1 GO:0016835 carbon-oxygen lyase activity 8/3513 79/18639 0.10126582278481 0.537288263844599 0.988506765023517 1 GO:0030515 snoRNA binding 2/3513 32/18639 0.0625 0.331607600341588 0.989488258573473 1 GO:0016881 acid-amino acid ligase activity 1/3513 22/18639 0.0454545454545455 0.241169163884792 0.989921831735556 1 GO:0042923 neuropeptide binding 2/3513 33/18639 0.0606060606060606 0.321558885179722 0.991237433709495 1 GO:0016917 GABA receptor activity 1/3513 23/18639 0.0434782608695652 0.230683548063714 0.991823566983608 1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/3513 23/18639 0.0434782608695652 0.230683548063714 0.991823566983608 1 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/3513 24/18639 0.0416666666666667 0.221071733561059 0.99336653051963 1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/3513 24/18639 0.0416666666666667 0.221071733561059 0.99336653051963 1 GO:0098960 postsynaptic neurotransmitter receptor activity 6/3513 69/18639 0.0869565217391304 0.461367096127427 0.994049044837095 1 GO:0022832 voltage-gated channel activity 21/3513 175/18639 0.12 0.63668659265585 0.994529163126753 1 GO:0001848 complement binding 1/3513 25/18639 0.04 0.212228864218617 0.994618390755168 1 GO:0015271 outward rectifier potassium channel activity 1/3513 25/18639 0.04 0.212228864218617 0.994618390755168 1 GO:0008083 growth factor activity 19/3513 162/18639 0.117283950617284 0.622275990764462 0.994688811811109 1 GO:0004252 serine-type endopeptidase activity 20/3513 176/18639 0.113636363636364 0.602922909711979 0.997432037307481 1 GO:0044183 protein folding chaperone 6/3513 75/18639 0.08 0.424457728437233 0.997482409277933 1 GO:0140662 ATP-dependent protein folding chaperone 2/3513 40/18639 0.05 0.265286080273271 0.997594207706347 1 GO:0008528 G protein-coupled peptide receptor activity 12/3513 122/18639 0.0983606557377049 0.521874256275287 0.99792846019113 1 GO:0003743 translation initiation factor activity 3/3513 51/18639 0.0588235294117647 0.31210127090973 0.998086842033259 1 GO:0005244 voltage-gated monoatomic ion channel activity 19/3513 173/18639 0.109826589595376 0.582709309270768 0.998272923966509 1 GO:0015079 potassium ion transmembrane transporter activity 17/3513 160/18639 0.10625 0.5637329205807 0.998428964274104 1 GO:0005184 neuropeptide hormone activity 1/3513 31/18639 0.032258064516129 0.171152309853723 0.998465995212454 1 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/3513 32/18639 0.03125 0.165803800170794 0.998755599620163 1 GO:0160041 neuropeptide activity 1/3513 32/18639 0.03125 0.165803800170794 0.998755599620163 1 GO:0030594 neurotransmitter receptor activity 8/3513 97/18639 0.0824742268041237 0.437585287048694 0.998942636435966 1 GO:0001653 peptide receptor activity 12/3513 128/18639 0.09375 0.497411400512383 0.999009548186378 1 GO:0022843 voltage-gated monoatomic cation channel activity 14/3513 143/18639 0.0979020979020979 0.519441276059551 0.999048194215966 1 GO:0005249 voltage-gated potassium channel activity 8/3513 98/18639 0.0816326530612245 0.433120131058401 0.999080742302812 1 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/3513 34/18639 0.0294117647058824 0.156050635454865 0.999181138074138 1 GO:0016229 steroid dehydrogenase activity 1/3513 35/18639 0.0285714285714286 0.15159204587044 0.99933575575463 1 GO:0022836 gated channel activity 39/3513 318/18639 0.122641509433962 0.650701706330664 0.99942852166508 1 GO:0030280 structural constituent of skin epidermis 1/3513 37/18639 0.027027027027027 0.143397881228795 0.99956293528898 1 GO:0016829 lyase activity 21/3513 200/18639 0.105 0.557100768573868 0.999577058094507 1 GO:0003735 structural constituent of ribosome 17/3513 175/18639 0.0971428571428571 0.515412955959497 0.999717168420368 1 GO:0005267 potassium channel activity 10/3513 124/18639 0.0806451612903226 0.427880774634308 0.9997769346634 1 GO:0005125 cytokine activity 25/3513 234/18639 0.106837606837607 0.56685059887451 0.999780177214009 1 GO:0008227 G protein-coupled amine receptor activity 1/3513 41/18639 0.024390243902439 0.129407844035742 0.999810802062027 1 GO:0005261 monoatomic cation channel activity 40/3513 341/18639 0.117302052785924 0.62237203583172 0.999870106881609 1 GO:0005216 monoatomic ion channel activity 56/3513 448/18639 0.125 0.663215200683177 0.99989505543438 1 GO:0003730 mRNA 3'-UTR binding 27/3513 262/18639 0.103053435114504 0.546772837204451 0.999951415344622 1 GO:0030527 structural constituent of chromatin 2/3513 98/18639 0.0204081632653061 0.1082800327646 0.999999970875716 1 GO:0003823 antigen binding 9/3513 174/18639 0.0517241379310345 0.274433876144763 0.999999972229099 1 GO:0005549 odorant binding 1/3513 111/18639 0.00900900900900901 0.0477992937429317 0.999999999920698 1 GO:0004984 olfactory receptor activity 4/3513 419/18639 0.00954653937947494 0.0506512802431066 1 1 GO:0030371 translation repressor activity 8/3513 329/18639 0.0243161094224924 0.129014507123779 1 1 GO:0045182 translation regulator activity 13/3513 356/18639 0.0365168539325843 0.193748260873737 1 1