ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 20/385 175/18639 0.114285714285714 5.53291280148423 6.34845462791091e-10 4.36773678400271e-07 GO:0005201 extracellular matrix structural constituent 15/385 168/18639 0.0892857142857143 4.32258812615956 2.215723308321e-06 0.000762208818062425 GO:0001968 fibronectin binding 6/385 30/18639 0.2 9.6825974025974 2.91461970576369e-05 0.00577071818700558 GO:0005520 insulin-like growth factor binding 5/385 19/18639 0.263157894736842 12.7402597402597 3.35506871337534e-05 0.00577071818700558 GO:0045296 cadherin binding 19/385 334/18639 0.0568862275449102 2.75403219534956 7.20491071072775e-05 0.00951670145907548 GO:0031994 insulin-like growth factor I binding 4/385 13/18639 0.307692307692308 14.8963036963037 0.000110540111175013 0.00951670145907548 GO:0005518 collagen binding 8/385 72/18639 0.111111111111111 5.37922077922078 0.000116381695904581 0.00951670145907548 GO:0019838 growth factor binding 11/385 136/18639 0.0808823529411765 3.91575630252101 0.000122818595394211 0.00951670145907548 GO:0140313 molecular sequestering activity 7/385 55/18639 0.127272727272727 6.16165289256198 0.000131264999565782 0.00951670145907548 GO:0044389 ubiquitin-like protein ligase binding 18/385 322/18639 0.0559006211180124 2.70631604420424 0.000138324149114469 0.00951670145907548 GO:0031625 ubiquitin protein ligase binding 17/385 302/18639 0.0562913907284768 2.72523436828073 0.000194218657222005 0.0121474941971581 GO:0008135 translation factor activity, RNA binding 8/385 83/18639 0.0963855421686747 4.66631200125176 0.000315022192301798 0.0180612723586364 GO:0180051 translation factor activity 8/385 84/18639 0.0952380952380952 4.61076066790353 0.000342018303985604 0.0181006610109304 GO:0003746 translation elongation factor activity 4/385 18/18639 0.222222222222222 10.7584415584416 0.000435900245505071 0.0214213834933921 GO:0005200 structural constituent of cytoskeleton 9/385 112/18639 0.0803571428571429 3.8903293135436 0.000527105936606258 0.0232177782962864 GO:0140311 protein sequestering activity 5/385 33/18639 0.151515151515152 7.33530106257379 0.000539948332471776 0.0232177782962864 GO:0031720 haptoglobin binding 3/385 10/18639 0.3 14.5238961038961 0.00094192824962121 0.03731178553915 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/385 22/18639 0.181818181818182 8.80236127508855 0.000976180435617296 0.03731178553915 GO:0048407 platelet-derived growth factor binding 3/385 11/18639 0.272727272727273 13.2035419126328 0.00127538108699727 0.046182220413375 GO:0002020 protease binding 9/385 136/18639 0.0661764705882353 3.20380061115355 0.00208640872535953 0.0717724601523679 GO:0050840 extracellular matrix binding 6/385 67/18639 0.0895522388059701 4.33549137429734 0.00258030290933759 0.0770255411259044 GO:0061134 peptidase regulator activity 12/385 226/18639 0.0530973451327434 2.57060108033559 0.00268407239200714 0.0770255411259044 GO:0004857 enzyme inhibitor activity 18/385 416/18639 0.0432692307692308 2.09479270729271 0.0026864521214547 0.0770255411259044 GO:0005344 oxygen carrier activity 3/385 14/18639 0.214285714285714 10.3742115027829 0.0026869374811362 0.0770255411259044 GO:0097110 scaffold protein binding 6/385 70/18639 0.0857142857142857 4.14968460111317 0.00321975175312967 0.0886075682461286 GO:0017070 U6 snRNA binding 3/385 16/18639 0.1875 9.07743506493506 0.00400909231343969 0.106086750447943 GO:0048306 calcium-dependent protein binding 6/385 80/18639 0.075 3.63097402597403 0.00621698640901425 0.150948790158557 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 15/385 349/18639 0.0429799426934097 2.08078740743497 0.00625063077206808 0.150948790158557 GO:0005178 integrin binding 9/385 161/18639 0.0559006211180124 2.70631604420424 0.0063626670270322 0.150948790158557 GO:0043394 proteoglycan binding 4/385 37/18639 0.108108108108108 5.23383643383643 0.00691142015851078 0.158470683361666 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 6/385 83/18639 0.072289156626506 3.49973400093882 0.00741866497285266 0.158470683361666 GO:0005501 retinoid binding 4/385 38/18639 0.105263157894737 5.0961038961039 0.00760106475426598 0.158470683361666 GO:0019840 isoprenoid binding 4/385 38/18639 0.105263157894737 5.0961038961039 0.00760106475426598 0.158470683361666 GO:0005212 structural constituent of eye lens 3/385 23/18639 0.130434782608696 6.31473743647657 0.0113961288553788 0.230604019191195 GO:0030020 extracellular matrix structural constituent conferring tensile strength 4/385 44/18639 0.0909090909090909 4.40118063754427 0.0126940465430414 0.242597333933679 GO:0030547 signaling receptor inhibitor activity 4/385 44/18639 0.0909090909090909 4.40118063754427 0.0126940465430414 0.242597333933679 GO:0042605 peptide antigen binding 4/385 45/18639 0.0888888888888889 4.30337662337662 0.0137109923137474 0.254950343563735 GO:0061135 endopeptidase regulator activity 9/385 184/18639 0.0489130434782609 2.36802653867871 0.0144815724522351 0.262192680187836 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 4/385 48/18639 0.0833333333333333 4.03441558441558 0.017066666098193 0.276942132378817 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/385 10/18639 0.2 9.6825974025974 0.0171609697835083 0.276942132378817 GO:0050815 phosphoserine residue binding 2/385 10/18639 0.2 9.6825974025974 0.0171609697835083 0.276942132378817 GO:0043539 protein serine/threonine kinase activator activity 5/385 73/18639 0.0684931506849315 3.31595801458815 0.0174975240067773 0.276942132378817 GO:0004722 protein serine/threonine phosphatase activity 6/385 103/18639 0.058252427184466 2.82017400075652 0.0200035105175519 0.276942132378817 GO:0019215 intermediate filament binding 2/385 11/18639 0.181818181818182 8.80236127508855 0.0206911006049552 0.276942132378817 GO:0034713 type I transforming growth factor beta receptor binding 2/385 11/18639 0.181818181818182 8.80236127508855 0.0206911006049552 0.276942132378817 GO:0050786 RAGE receptor binding 2/385 11/18639 0.181818181818182 8.80236127508855 0.0206911006049552 0.276942132378817 GO:0003743 translation initiation factor activity 4/385 51/18639 0.0784313725490196 3.79709702062643 0.0208939127449144 0.276942132378817 GO:0043236 laminin binding 3/385 29/18639 0.103448275862069 5.00824003582624 0.0214727577925193 0.276942132378817 GO:0005080 protein kinase C binding 4/385 52/18639 0.0769230769230769 3.72407592407592 0.0222772051620098 0.276942132378817 GO:0030414 peptidase inhibitor activity 8/385 169/18639 0.0473372781065089 2.29173903020057 0.0244118939487402 0.276942132378817 GO:0005095 GTPase inhibitor activity 2/385 12/18639 0.166666666666667 8.06883116883117 0.0244944053355236 0.276942132378817 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/385 12/18639 0.166666666666667 8.06883116883117 0.0244944053355236 0.276942132378817 GO:0070410 co-SMAD binding 2/385 12/18639 0.166666666666667 8.06883116883117 0.0244944053355236 0.276942132378817 GO:0003925 G protein activity 4/385 54/18639 0.0740740740740741 3.58614718614719 0.0252080199196746 0.276942132378817 GO:0140297 DNA-binding transcription factor binding 17/385 488/18639 0.0348360655737705 1.68651799020651 0.0257181888875758 0.276942132378817 GO:0033192 calmodulin-dependent protein phosphatase activity 5/385 81/18639 0.0617283950617284 2.98845598845599 0.0261559502543012 0.276942132378817 GO:0140791 histone H2AXS140 phosphatase activity 5/385 81/18639 0.0617283950617284 2.98845598845599 0.0261559502543012 0.276942132378817 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 5/385 81/18639 0.0617283950617284 2.98845598845599 0.0261559502543012 0.276942132378817 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 5/385 81/18639 0.0617283950617284 2.98845598845599 0.0261559502543012 0.276942132378817 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 5/385 81/18639 0.0617283950617284 2.98845598845599 0.0261559502543012 0.276942132378817 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 5/385 81/18639 0.0617283950617284 2.98845598845599 0.0261559502543012 0.276942132378817 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 5/385 81/18639 0.0617283950617284 2.98845598845599 0.0261559502543012 0.276942132378817 GO:1990439 MAP kinase serine/threonine phosphatase activity 5/385 81/18639 0.0617283950617284 2.98845598845599 0.0261559502543012 0.276942132378817 GO:0008201 heparin binding 8/385 172/18639 0.0465116279069767 2.25176683781335 0.0267515662910636 0.276942132378817 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 5/385 82/18639 0.0609756097560976 2.95201140323092 0.0273997815083134 0.276942132378817 GO:0033549 MAP kinase phosphatase activity 5/385 82/18639 0.0609756097560976 2.95201140323092 0.0273997815083134 0.276942132378817 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/385 13/18639 0.153846153846154 7.44815184815185 0.0285581539411834 0.276942132378817 GO:0005542 folic acid binding 2/385 13/18639 0.153846153846154 7.44815184815185 0.0285581539411834 0.276942132378817 GO:0039706 co-receptor binding 2/385 13/18639 0.153846153846154 7.44815184815185 0.0285581539411834 0.276942132378817 GO:0005539 glycosaminoglycan binding 10/385 242/18639 0.0413223140495868 2.00053665342922 0.0293631131650687 0.276942132378817 GO:0017018 myosin phosphatase activity 5/385 84/18639 0.0595238095238095 2.8817254174397 0.0299987579607629 0.276942132378817 GO:0051117 ATPase binding 5/385 84/18639 0.0595238095238095 2.8817254174397 0.0299987579607629 0.276942132378817 GO:0004601 peroxidase activity 4/385 57/18639 0.0701754385964912 3.3974025974026 0.0300205780433734 0.276942132378817 GO:0016504 peptidase activator activity 4/385 57/18639 0.0701754385964912 3.3974025974026 0.0300205780433734 0.276942132378817 GO:0140416 transcription regulator inhibitor activity 3/385 33/18639 0.0909090909090909 4.40118063754427 0.0301899126866443 0.276942132378817 GO:0019825 oxygen binding 3/385 34/18639 0.0882352941176471 4.27173414820474 0.0326185652142621 0.288853841345082 GO:0030332 cyclin binding 3/385 34/18639 0.0882352941176471 4.27173414820474 0.0326185652142621 0.288853841345082 GO:0016209 antioxidant activity 5/385 86/18639 0.0581395348837209 2.81470854726669 0.0327479645710994 0.288853841345082 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/385 59/18639 0.0677966101694915 3.28223640766014 0.0335099572251709 0.291833551530602 GO:0022853 active monoatomic ion transmembrane transporter activity 6/385 118/18639 0.0508474576271186 2.4616773057451 0.035801006465191 0.295305433454662 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/385 15/18639 0.133333333333333 6.45506493506493 0.0374180861488499 0.295305433454662 GO:0033130 acetylcholine receptor binding 2/385 15/18639 0.133333333333333 6.45506493506493 0.0374180861488499 0.295305433454662 GO:0051371 muscle alpha-actinin binding 2/385 15/18639 0.133333333333333 6.45506493506493 0.0374180861488499 0.295305433454662 GO:0061578 K63-linked deubiquitinase activity 2/385 15/18639 0.133333333333333 6.45506493506493 0.0374180861488499 0.295305433454662 GO:0120283 protein serine/threonine kinase binding 2/385 15/18639 0.133333333333333 6.45506493506493 0.0374180861488499 0.295305433454662 GO:0140776 protein-containing complex destabilizing activity 2/385 15/18639 0.133333333333333 6.45506493506493 0.0374180861488499 0.295305433454662 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/385 36/18639 0.0833333333333333 4.03441558441558 0.0377716252093173 0.295305433454662 GO:0044390 ubiquitin-like protein conjugating enzyme binding 3/385 36/18639 0.0833333333333333 4.03441558441558 0.0377716252093173 0.295305433454662 GO:0019887 protein kinase regulator activity 10/385 255/18639 0.0392156862745098 1.89854851031322 0.0397525245807136 0.307300414736303 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/385 16/18639 0.125 6.05162337662338 0.0421907995539085 0.318980990033946 GO:0019841 retinol binding 2/385 16/18639 0.125 6.05162337662338 0.0421907995539085 0.318980990033946 GO:0003924 GTPase activity 12/385 331/18639 0.0362537764350453 1.75515360772158 0.0430590821706838 0.322007049276418 GO:0004549 tRNA-specific ribonuclease activity 2/385 17/18639 0.117647058823529 5.69564553093965 0.0471769946894302 0.341660761540295 GO:0008429 phosphatidylethanolamine binding 2/385 17/18639 0.117647058823529 5.69564553093965 0.0471769946894302 0.341660761540295 GO:0030548 acetylcholine receptor regulator activity 2/385 17/18639 0.117647058823529 5.69564553093965 0.0471769946894302 0.341660761540295 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 6/385 128/18639 0.046875 2.26935876623377 0.0498406216847619 0.349783649463807 GO:0004866 endopeptidase inhibitor activity 7/385 161/18639 0.0434782608695652 2.10491247882552 0.0500209261405473 0.349783649463807 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 4/385 68/18639 0.0588235294117647 2.84782276546982 0.0520235165027439 0.349783649463807 GO:0008137 NADH dehydrogenase (ubiquinone) activity 3/385 41/18639 0.0731707317073171 3.5424136838771 0.052341168984767 0.349783649463807 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/385 18/18639 0.111111111111111 5.37922077922078 0.0523658661261222 0.349783649463807 GO:0017128 phospholipid scramblase activity 2/385 18/18639 0.111111111111111 5.37922077922078 0.0523658661261222 0.349783649463807 GO:0050811 GABA receptor binding 2/385 18/18639 0.111111111111111 5.37922077922078 0.0523658661261222 0.349783649463807 GO:0099602 neurotransmitter receptor regulator activity 2/385 18/18639 0.111111111111111 5.37922077922078 0.0523658661261222 0.349783649463807 GO:0035198 miRNA binding 3/385 42/18639 0.0714285714285714 3.45807050092764 0.0555360391616557 0.367392259069414 GO:0016918 retinal binding 2/385 19/18639 0.105263157894737 5.0961038961039 0.0577469616972926 0.372285459260671 GO:0008200 ion channel inhibitor activity 3/385 43/18639 0.0697674418604651 3.37765025672002 0.058821745903906 0.372285459260671 GO:0016247 channel regulator activity 7/385 168/18639 0.0416666666666667 2.01720779220779 0.0601641563100178 0.372285459260671 GO:0042379 chemokine receptor binding 4/385 72/18639 0.0555555555555556 2.68961038961039 0.0617220297717042 0.372285459260671 GO:0003714 transcription corepressor activity 8/385 204/18639 0.0392156862745098 1.89854851031322 0.0618291795622425 0.372285459260671 GO:0003954 NADH dehydrogenase activity 3/385 44/18639 0.0681818181818182 3.30088547815821 0.0621969434181156 0.372285459260671 GO:0016248 channel inhibitor activity 3/385 44/18639 0.0681818181818182 3.30088547815821 0.0621969434181156 0.372285459260671 GO:0140789 histone phosphatase activity 6/385 136/18639 0.0441176470588235 2.13586707410237 0.0632032314042835 0.372285459260671 GO:0141108 transporter regulator activity 7/385 170/18639 0.0411764705882353 1.99347593582888 0.0632779435492713 0.372285459260671 GO:0016004 phospholipase activator activity 2/385 20/18639 0.1 4.8412987012987 0.0633101725777595 0.372285459260671 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/385 20/18639 0.1 4.8412987012987 0.0633101725777595 0.372285459260671 GO:0030742 GTP-dependent protein binding 2/385 20/18639 0.1 4.8412987012987 0.0633101725777595 0.372285459260671 GO:0043024 ribosomal small subunit binding 2/385 20/18639 0.1 4.8412987012987 0.0633101725777595 0.372285459260671 GO:0016922 nuclear receptor binding 6/385 137/18639 0.0437956204379562 2.12027680348848 0.0650083988657252 0.376451960335176 GO:0008009 chemokine activity 3/385 45/18639 0.0666666666666667 3.22753246753247 0.0656602256398562 0.376451960335176 GO:0141110 transporter inhibitor activity 3/385 45/18639 0.0666666666666667 3.22753246753247 0.0656602256398562 0.376451960335176 GO:0030295 protein kinase activator activity 6/385 139/18639 0.0431654676258993 2.08976922358217 0.0687087163219368 0.387249847644662 GO:0030291 protein serine/threonine kinase inhibitor activity 3/385 46/18639 0.0652173913043478 3.15736871823828 0.0692101308505959 0.387249847644662 GO:0044183 protein folding chaperone 4/385 75/18639 0.0533333333333333 2.58202597402597 0.0695779019997886 0.387249847644662 GO:0003823 antigen binding 7/385 174/18639 0.0402298850574713 1.94764890282132 0.0697950306801426 0.387249847644662 GO:0004721 phosphoprotein phosphatase activity 7/385 175/18639 0.04 1.93651948051948 0.0714847072522207 0.393451828716223 GO:0098631 cell adhesion mediator activity 4/385 76/18639 0.0526315789473684 2.54805194805195 0.0723055244365635 0.394625673354356 GO:0005504 fatty acid binding 3/385 47/18639 0.0638297872340425 3.09019066040343 0.0728451460988418 0.394625673354356 GO:0140104 molecular carrier activity 9/385 249/18639 0.036144578313253 1.74986700046941 0.0743793748175088 0.395829632775155 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 2/385 22/18639 0.0909090909090909 4.40118063754427 0.0749441639425627 0.395829632775155 GO:0061133 endopeptidase activator activity 2/385 22/18639 0.0909090909090909 4.40118063754427 0.0749441639425627 0.395829632775155 GO:0019207 kinase regulator activity 10/385 287/18639 0.0348432055749129 1.68686365898909 0.0753687236824786 0.395829632775155 GO:0032266 phosphatidylinositol-3-phosphate binding 3/385 48/18639 0.0625 3.02581168831169 0.0765637114322184 0.399059344434593 GO:0033293 monocarboxylic acid binding 4/385 79/18639 0.0506329113924051 2.45129048167023 0.0808094057129817 0.403807928544552 GO:0046332 SMAD binding 4/385 79/18639 0.0506329113924051 2.45129048167023 0.0808094057129817 0.403807928544552 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/385 23/18639 0.0869565217391304 4.20982495765104 0.0809963577603897 0.403807928544552 GO:0005158 insulin receptor binding 2/385 23/18639 0.0869565217391304 4.20982495765104 0.0809963577603897 0.403807928544552 GO:0070577 lysine-acetylated histone binding 2/385 23/18639 0.0869565217391304 4.20982495765104 0.0809963577603897 0.403807928544552 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/385 23/18639 0.0869565217391304 4.20982495765104 0.0809963577603897 0.403807928544552 GO:0043022 ribosome binding 5/385 112/18639 0.0446428571428571 2.16129406307978 0.0826412965961474 0.409044691065823 GO:0001618 virus receptor activity 4/385 81/18639 0.0493827160493827 2.39076479076479 0.0867413056662651 0.413718007689891 GO:0019209 kinase activator activity 6/385 148/18639 0.0405405405405405 1.96268866268866 0.0868372425460945 0.413718007689891 GO:0048027 mRNA 5'-UTR binding 2/385 24/18639 0.0833333333333333 4.03441558441558 0.0871934754578986 0.413718007689891 GO:0050431 transforming growth factor beta binding 2/385 24/18639 0.0833333333333333 4.03441558441558 0.0871934754578986 0.413718007689891 GO:0060229 lipase activator activity 2/385 24/18639 0.0833333333333333 4.03441558441558 0.0871934754578986 0.413718007689891 GO:0140033 acetylation-dependent protein binding 2/385 24/18639 0.0833333333333333 4.03441558441558 0.0871934754578986 0.413718007689891 GO:0140272 exogenous protein binding 4/385 82/18639 0.0487804878048781 2.36160912258473 0.0897844607512883 0.423093897238948 GO:0009055 electron transfer activity 5/385 116/18639 0.0431034482758621 2.08676668159427 0.0926413647853101 0.433586795729887 GO:0004860 protein kinase inhibitor activity 4/385 84/18639 0.0476190476190476 2.30538033395176 0.0960223043901255 0.444902341513842 GO:0016860 intramolecular oxidoreductase activity 3/385 53/18639 0.0566037735849057 2.7403577554521 0.0963523966359919 0.444902341513842 GO:0005160 transforming growth factor beta receptor binding 2/385 26/18639 0.0769230769230769 3.72407592407592 0.0999886429234278 0.446256152651001 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 2/385 26/18639 0.0769230769230769 3.72407592407592 0.0999886429234278 0.446256152651001 GO:0050681 nuclear androgen receptor binding 2/385 26/18639 0.0769230769230769 3.72407592407592 0.0999886429234278 0.446256152651001 GO:0050750 low-density lipoprotein particle receptor binding 2/385 26/18639 0.0769230769230769 3.72407592407592 0.0999886429234278 0.446256152651001 GO:0017069 snRNA binding 3/385 54/18639 0.0555555555555556 2.68961038961039 0.100537359972246 0.446256152651001 GO:0140463 chromatin-protein adaptor activity 3/385 54/18639 0.0555555555555556 2.68961038961039 0.100537359972246 0.446256152651001 GO:0098632 cell-cell adhesion mediator activity 3/385 55/18639 0.0545454545454545 2.64070838252656 0.104793956411611 0.461135189764252 GO:0051082 unfolded protein binding 5/385 121/18639 0.0413223140495868 2.00053665342922 0.105971002524355 0.461135189764252 GO:0023026 MHC class II protein complex binding 2/385 27/18639 0.0740740740740741 3.58614718614719 0.106570487169355 0.461135189764252 GO:0035255 ionotropic glutamate receptor binding 2/385 27/18639 0.0740740740740741 3.58614718614719 0.106570487169355 0.461135189764252 GO:0051393 alpha-actinin binding 2/385 28/18639 0.0714285714285714 3.45807050092764 0.113264827972007 0.484013674812056 GO:0097718 disordered domain specific binding 2/385 28/18639 0.0714285714285714 3.45807050092764 0.113264827972007 0.484013674812056 GO:0099106 ion channel regulator activity 6/385 160/18639 0.0375 1.81548701298701 0.114680326825486 0.485907044221129 GO:0019210 kinase inhibitor activity 4/385 90/18639 0.0444444444444444 2.15168831168831 0.115902639134671 0.485907044221129 GO:1901681 sulfur compound binding 9/385 275/18639 0.0327272727272727 1.58442502951594 0.117746811775772 0.485907044221129 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 3/385 58/18639 0.0517241379310345 2.50412001791312 0.117975422642179 0.485907044221129 GO:0061980 regulatory RNA binding 3/385 58/18639 0.0517241379310345 2.50412001791312 0.117975422642179 0.485907044221129 GO:0072341 modified amino acid binding 4/385 91/18639 0.043956043956044 2.12804338518624 0.119379076642647 0.485907044221129 GO:0003785 actin monomer binding 2/385 29/18639 0.0689655172413793 3.33882669055083 0.120064240577895 0.485907044221129 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/385 29/18639 0.0689655172413793 3.33882669055083 0.120064240577895 0.485907044221129 GO:0097472 cyclin-dependent protein kinase activity 2/385 29/18639 0.0689655172413793 3.33882669055083 0.120064240577895 0.485907044221129 GO:0004879 nuclear receptor activity 3/385 59/18639 0.0508474576271186 2.4616773057451 0.122500358289519 0.486873393602884 GO:0015459 potassium channel regulator activity 3/385 59/18639 0.0508474576271186 2.4616773057451 0.122500358289519 0.486873393602884 GO:0045309 protein phosphorylated amino acid binding 3/385 59/18639 0.0508474576271186 2.4616773057451 0.122500358289519 0.486873393602884 GO:0042826 histone deacetylase binding 5/385 127/18639 0.0393700787401575 1.90602311074752 0.123133678033288 0.486873393602884 GO:0031624 ubiquitin conjugating enzyme binding 2/385 30/18639 0.0666666666666667 3.22753246753247 0.12696155752243 0.488674174404826 GO:0048019 receptor antagonist activity 2/385 30/18639 0.0666666666666667 3.22753246753247 0.12696155752243 0.488674174404826 GO:0098531 ligand-modulated transcription factor activity 3/385 60/18639 0.05 2.42064935064935 0.127087767837332 0.488674174404826 GO:0019001 guanyl nucleotide binding 12/385 400/18639 0.03 1.45238961038961 0.127140519212884 0.488674174404826 GO:0032561 guanyl ribonucleotide binding 12/385 400/18639 0.03 1.45238961038961 0.127140519212884 0.488674174404826 GO:0015399 primary active transmembrane transporter activity 6/385 166/18639 0.036144578313253 1.74986700046941 0.130102239870952 0.496159572259344 GO:0003779 actin binding 13/385 443/18639 0.0293453724604966 1.42069713582129 0.130530352585671 0.496159572259344 GO:0008276 protein methyltransferase activity 4/385 95/18639 0.0421052631578947 2.03844155844156 0.133723950942667 0.500856002803196 GO:0016411 acylglycerol O-acyltransferase activity 2/385 31/18639 0.0645161290322581 3.1234185169669 0.133949861214808 0.500856002803196 GO:0070325 lipoprotein particle receptor binding 2/385 31/18639 0.0645161290322581 3.1234185169669 0.133949861214808 0.500856002803196 GO:0043425 bHLH transcription factor binding 2/385 32/18639 0.0625 3.02581168831169 0.141022476718179 0.521631526785521 GO:0051059 NF-kappaB binding 2/385 32/18639 0.0625 3.02581168831169 0.141022476718179 0.521631526785521 GO:0008170 N-methyltransferase activity 4/385 98/18639 0.0408163265306122 1.97604028624437 0.144921971099667 0.533188856238346 GO:0019956 chemokine binding 2/385 33/18639 0.0606060606060606 2.93412042502952 0.148172964720213 0.542249998550567 GO:0019843 rRNA binding 3/385 65/18639 0.0461538461538462 2.23444555444555 0.150896686963661 0.546404845426311 GO:0038024 cargo receptor activity 3/385 65/18639 0.0461538461538462 2.23444555444555 0.150896686963661 0.546404845426311 GO:0043130 ubiquitin binding 4/385 100/18639 0.04 1.93651948051948 0.152584499068965 0.549623745337423 GO:0043021 ribonucleoprotein complex binding 6/385 177/18639 0.0338983050847458 1.64111820383007 0.160775450788365 0.571643781341284 GO:0042054 histone methyltransferase activity 3/385 67/18639 0.0447761194029851 2.16774568714867 0.160792304260943 0.571643781341284 GO:0005525 GTP binding 11/385 378/18639 0.0291005291005291 1.40884353741497 0.161190252296816 0.571643781341284 GO:0001664 G protein-coupled receptor binding 9/385 297/18639 0.0303030303030303 1.46706021251476 0.163230800605933 0.575911747778882 GO:0002039 p53 binding 3/385 69/18639 0.0434782608695652 2.10491247882552 0.170878233148057 0.580952290053711 GO:0022829 wide pore channel activity 2/385 37/18639 0.0540540540540541 2.61691821691822 0.177432724107819 0.580952290053711 GO:0023023 MHC protein complex binding 2/385 37/18639 0.0540540540540541 2.61691821691822 0.177432724107819 0.580952290053711 GO:0030280 structural constituent of skin epidermis 2/385 37/18639 0.0540540540540541 2.61691821691822 0.177432724107819 0.580952290053711 GO:0042805 actinin binding 2/385 37/18639 0.0540540540540541 2.61691821691822 0.177432724107819 0.580952290053711 GO:0019888 protein phosphatase regulator activity 4/385 107/18639 0.0373831775700935 1.80983129020512 0.18054023051318 0.580952290053711 GO:0015078 proton transmembrane transporter activity 6/385 185/18639 0.0324324324324324 1.57015093015093 0.184860049510636 0.580952290053711 GO:1901981 phosphatidylinositol phosphate binding 6/385 185/18639 0.0324324324324324 1.57015093015093 0.184860049510636 0.580952290053711 GO:0001094 TFIID-class transcription factor complex binding 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0005381 iron ion transmembrane transporter activity 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0008190 eukaryotic initiation factor 4E binding 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0016783 sulfurtransferase activity 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0019911 structural constituent of myelin sheath 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0030957 Tat protein binding 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0031996 thioesterase binding 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0033204 ribonuclease P RNA binding 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0047429 nucleoside triphosphate diphosphatase activity 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0051880 G-quadruplex DNA binding 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0097177 mitochondrial ribosome binding 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0140940 histone H2A methyltransferase activity 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0141109 transporter activator activity 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:1990259 histone H2AQ104 methyltransferase activity 1/385 10/18639 0.1 4.8412987012987 0.188418279868754 0.580952290053711 GO:0031406 carboxylic acid binding 6/385 187/18639 0.0320855614973262 1.55335787207445 0.191093509201124 0.580952290053711 GO:0004521 RNA endonuclease activity 3/385 73/18639 0.0410958904109589 1.98957480875289 0.191562394441955 0.580952290053711 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/385 39/18639 0.0512820512820513 2.48271728271728 0.192378615248084 0.580952290053711 GO:0140597 protein carrier chaperone 6/385 188/18639 0.0319148936170213 1.54509533020171 0.194240277179569 0.580952290053711 GO:0043177 organic acid binding 6/385 189/18639 0.0317460317460317 1.53692022263451 0.197406618953931 0.580952290053711 GO:0015036 disulfide oxidoreductase activity 2/385 40/18639 0.05 2.42064935064935 0.199912309941352 0.580952290053711 GO:0030331 nuclear estrogen receptor binding 2/385 40/18639 0.05 2.42064935064935 0.199912309941352 0.580952290053711 GO:0061791 GTPase motor activity 2/385 40/18639 0.05 2.42064935064935 0.199912309941352 0.580952290053711 GO:0140662 ATP-dependent protein folding chaperone 2/385 40/18639 0.05 2.42064935064935 0.199912309941352 0.580952290053711 GO:1990606 membrane scission GTPase motor activity 2/385 40/18639 0.05 2.42064935064935 0.199912309941352 0.580952290053711 GO:0003725 double-stranded RNA binding 3/385 75/18639 0.04 1.93651948051948 0.202131783979604 0.580952290053711 GO:0016791 phosphatase activity 8/385 273/18639 0.0293040293040293 1.41869559012416 0.204842181224587 0.580952290053711 GO:0002162 dystroglycan binding 1/385 11/18639 0.0909090909090909 4.40118063754427 0.205190997795134 0.580952290053711 GO:0008199 ferric iron binding 1/385 11/18639 0.0909090909090909 4.40118063754427 0.205190997795134 0.580952290053711 GO:0008271 secondary active sulfate transmembrane transporter activity 1/385 11/18639 0.0909090909090909 4.40118063754427 0.205190997795134 0.580952290053711 GO:0008503 benzodiazepine receptor activity 1/385 11/18639 0.0909090909090909 4.40118063754427 0.205190997795134 0.580952290053711 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/385 11/18639 0.0909090909090909 4.40118063754427 0.205190997795134 0.580952290053711 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/385 11/18639 0.0909090909090909 4.40118063754427 0.205190997795134 0.580952290053711 GO:0032050 clathrin heavy chain binding 1/385 11/18639 0.0909090909090909 4.40118063754427 0.205190997795134 0.580952290053711 GO:0032794 GTPase activating protein binding 1/385 11/18639 0.0909090909090909 4.40118063754427 0.205190997795134 0.580952290053711 GO:0034056 estrogen response element binding 1/385 11/18639 0.0909090909090909 4.40118063754427 0.205190997795134 0.580952290053711 GO:0042608 T cell receptor binding 1/385 11/18639 0.0909090909090909 4.40118063754427 0.205190997795134 0.580952290053711 GO:1990948 ubiquitin ligase inhibitor activity 1/385 11/18639 0.0909090909090909 4.40118063754427 0.205190997795134 0.580952290053711 GO:0017080 sodium channel regulator activity 2/385 41/18639 0.0487804878048781 2.36160912258473 0.207480060759639 0.585025745092751 GO:0005126 cytokine receptor binding 8/385 275/18639 0.0290909090909091 1.40837780401417 0.210207954976963 0.58804214937352 GO:0001221 transcription coregulator binding 4/385 115/18639 0.0347826086956522 1.68392998306042 0.214361992141946 0.58804214937352 GO:0042056 chemoattractant activity 2/385 42/18639 0.0476190476190476 2.30538033395176 0.215077261839538 0.58804214937352 GO:0048487 beta-tubulin binding 2/385 42/18639 0.0476190476190476 2.30538033395176 0.215077261839538 0.58804214937352 GO:0004300 enoyl-CoA hydratase activity 1/385 12/18639 0.0833333333333333 4.03441558441558 0.221617960746007 0.58804214937352 GO:0004526 ribonuclease P activity 1/385 12/18639 0.0833333333333333 4.03441558441558 0.221617960746007 0.58804214937352 GO:0016840 carbon-nitrogen lyase activity 1/385 12/18639 0.0833333333333333 4.03441558441558 0.221617960746007 0.58804214937352 GO:0034452 dynactin binding 1/385 12/18639 0.0833333333333333 4.03441558441558 0.221617960746007 0.58804214937352 GO:0035259 nuclear glucocorticoid receptor binding 1/385 12/18639 0.0833333333333333 4.03441558441558 0.221617960746007 0.58804214937352 GO:0036009 protein-glutamine N-methyltransferase activity 1/385 12/18639 0.0833333333333333 4.03441558441558 0.221617960746007 0.58804214937352 GO:0097371 MDM2/MDM4 family protein binding 1/385 12/18639 0.0833333333333333 4.03441558441558 0.221617960746007 0.58804214937352 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/385 12/18639 0.0833333333333333 4.03441558441558 0.221617960746007 0.58804214937352 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/385 12/18639 0.0833333333333333 4.03441558441558 0.221617960746007 0.58804214937352 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/385 12/18639 0.0833333333333333 4.03441558441558 0.221617960746007 0.58804214937352 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/385 12/18639 0.0833333333333333 4.03441558441558 0.221617960746007 0.58804214937352 GO:0048156 tau protein binding 2/385 43/18639 0.0465116279069767 2.25176683781335 0.222699482129081 0.58804214937352 GO:0019208 phosphatase regulator activity 4/385 117/18639 0.0341880341880342 1.65514485514486 0.223079943294315 0.58804214937352 GO:0005543 phospholipid binding 13/385 497/18639 0.0261569416498994 1.26633567639604 0.230080085713942 0.595437978533959 GO:0019205 nucleobase-containing compound kinase activity 2/385 44/18639 0.0454545454545455 2.20059031877214 0.230342460162936 0.595437978533959 GO:0032182 ubiquitin-like protein binding 4/385 120/18639 0.0333333333333333 1.61376623376623 0.236325300591519 0.595437978533959 GO:0004465 lipoprotein lipase activity 1/385 13/18639 0.0769230769230769 3.72407592407592 0.237706277979742 0.595437978533959 GO:0019855 calcium channel inhibitor activity 1/385 13/18639 0.0769230769230769 3.72407592407592 0.237706277979742 0.595437978533959 GO:0035325 Toll-like receptor binding 1/385 13/18639 0.0769230769230769 3.72407592407592 0.237706277979742 0.595437978533959 GO:0046974 histone H3K9 methyltransferase activity 1/385 13/18639 0.0769230769230769 3.72407592407592 0.237706277979742 0.595437978533959 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/385 13/18639 0.0769230769230769 3.72407592407592 0.237706277979742 0.595437978533959 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/385 13/18639 0.0769230769230769 3.72407592407592 0.237706277979742 0.595437978533959 GO:0097157 pre-mRNA intronic binding 1/385 13/18639 0.0769230769230769 3.72407592407592 0.237706277979742 0.595437978533959 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/385 13/18639 0.0769230769230769 3.72407592407592 0.237706277979742 0.595437978533959 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/385 45/18639 0.0444444444444444 2.15168831168831 0.238002098977963 0.595437978533959 GO:0046915 transition metal ion transmembrane transporter activity 2/385 45/18639 0.0444444444444444 2.15168831168831 0.238002098977963 0.595437978533959 GO:0140303 intramembrane lipid transporter activity 2/385 45/18639 0.0444444444444444 2.15168831168831 0.238002098977963 0.595437978533959 GO:0005254 chloride channel activity 3/385 83/18639 0.036144578313253 1.74986700046941 0.245599957445129 0.60457367375949 GO:0140713 histone chaperone activity 5/385 164/18639 0.0304878048780488 1.47600570161546 0.251778020852459 0.60457367375949 GO:0005161 platelet-derived growth factor receptor binding 1/385 14/18639 0.0714285714285714 3.45807050092764 0.253462912951169 0.60457367375949 GO:0005545 1-phosphatidylinositol binding 1/385 14/18639 0.0714285714285714 3.45807050092764 0.253462912951169 0.60457367375949 GO:0008191 metalloendopeptidase inhibitor activity 1/385 14/18639 0.0714285714285714 3.45807050092764 0.253462912951169 0.60457367375949 GO:0034236 protein kinase A catalytic subunit binding 1/385 14/18639 0.0714285714285714 3.45807050092764 0.253462912951169 0.60457367375949 GO:0061665 SUMO ligase activity 1/385 14/18639 0.0714285714285714 3.45807050092764 0.253462912951169 0.60457367375949 GO:0070742 C2H2 zinc finger domain binding 1/385 14/18639 0.0714285714285714 3.45807050092764 0.253462912951169 0.60457367375949 GO:1901612 cardiolipin binding 1/385 14/18639 0.0714285714285714 3.45807050092764 0.253462912951169 0.60457367375949 GO:0042277 peptide binding 7/385 249/18639 0.0281124497991968 1.36100766703176 0.256796112049079 0.60457367375949 GO:0005516 calmodulin binding 6/385 207/18639 0.0289855072463768 1.40327498588368 0.257346374990703 0.60457367375949 GO:0140693 molecular condensate scaffold activity 2/385 48/18639 0.0416666666666667 2.01720779220779 0.26104237504113 0.60457367375949 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 5/385 167/18639 0.029940119760479 1.44949062913135 0.263475673978769 0.60457367375949 GO:0004518 nuclease activity 6/385 209/18639 0.0287081339712919 1.38984651711924 0.264300172353354 0.60457367375949 GO:0051015 actin filament binding 6/385 209/18639 0.0287081339712919 1.38984651711924 0.264300172353354 0.60457367375949 GO:0004519 endonuclease activity 4/385 127/18639 0.031496062992126 1.52481848859802 0.267896183541248 0.60457367375949 GO:0001222 transcription corepressor binding 2/385 49/18639 0.0408163265306122 1.97604028624437 0.268730807002582 0.60457367375949 GO:0016763 pentosyltransferase activity 2/385 49/18639 0.0408163265306122 1.97604028624437 0.268730807002582 0.60457367375949 GO:0035254 glutamate receptor binding 2/385 49/18639 0.0408163265306122 1.97604028624437 0.268730807002582 0.60457367375949 GO:0060590 ATPase regulator activity 2/385 49/18639 0.0408163265306122 1.97604028624437 0.268730807002582 0.60457367375949 GO:0004129 cytochrome-c oxidase activity 1/385 15/18639 0.0666666666666667 3.22753246753247 0.268894686294192 0.60457367375949 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/385 15/18639 0.0666666666666667 3.22753246753247 0.268894686294192 0.60457367375949 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/385 15/18639 0.0666666666666667 3.22753246753247 0.268894686294192 0.60457367375949 GO:0005523 tropomyosin binding 1/385 15/18639 0.0666666666666667 3.22753246753247 0.268894686294192 0.60457367375949 GO:0015116 sulfate transmembrane transporter activity 1/385 15/18639 0.0666666666666667 3.22753246753247 0.268894686294192 0.60457367375949 GO:0016846 carbon-sulfur lyase activity 1/385 15/18639 0.0666666666666667 3.22753246753247 0.268894686294192 0.60457367375949 GO:0031386 protein tag activity 1/385 15/18639 0.0666666666666667 3.22753246753247 0.268894686294192 0.60457367375949 GO:0045504 dynein heavy chain binding 1/385 15/18639 0.0666666666666667 3.22753246753247 0.268894686294192 0.60457367375949 GO:0050780 dopamine receptor binding 1/385 15/18639 0.0666666666666667 3.22753246753247 0.268894686294192 0.60457367375949 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/385 15/18639 0.0666666666666667 3.22753246753247 0.268894686294192 0.60457367375949 GO:0141047 molecular tag activity 1/385 15/18639 0.0666666666666667 3.22753246753247 0.268894686294192 0.60457367375949 GO:0004197 cysteine-type endopeptidase activity 3/385 88/18639 0.0340909090909091 1.6504427390791 0.273467037904998 0.610219718073548 GO:0016651 oxidoreductase activity, acting on NAD(P)H 3/385 88/18639 0.0340909090909091 1.6504427390791 0.273467037904998 0.610219718073548 GO:0048020 CCR chemokine receptor binding 2/385 50/18639 0.04 1.93651948051948 0.276417713891799 0.610219718073548 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/385 89/18639 0.0337078651685393 1.63189843864001 0.279083157522835 0.610219718073548 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/385 89/18639 0.0337078651685393 1.63189843864001 0.279083157522835 0.610219718073548 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/385 16/18639 0.0625 3.02581168831169 0.284008278743544 0.610219718073548 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/385 16/18639 0.0625 3.02581168831169 0.284008278743544 0.610219718073548 GO:0005159 insulin-like growth factor receptor binding 1/385 16/18639 0.0625 3.02581168831169 0.284008278743544 0.610219718073548 GO:0005521 lamin binding 1/385 16/18639 0.0625 3.02581168831169 0.284008278743544 0.610219718073548 GO:0015385 sodium:proton antiporter activity 1/385 16/18639 0.0625 3.02581168831169 0.284008278743544 0.610219718073548 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/385 16/18639 0.0625 3.02581168831169 0.284008278743544 0.610219718073548 GO:0016722 oxidoreductase activity, acting on metal ions 1/385 16/18639 0.0625 3.02581168831169 0.284008278743544 0.610219718073548 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/385 16/18639 0.0625 3.02581168831169 0.284008278743544 0.610219718073548 GO:0070411 I-SMAD binding 1/385 16/18639 0.0625 3.02581168831169 0.284008278743544 0.610219718073548 GO:0140793 histone H2AXY142 phosphatase activity 3/385 90/18639 0.0333333333333333 1.61376623376623 0.284710071950013 0.610219718073548 GO:0140030 modification-dependent protein binding 5/385 173/18639 0.0289017341040462 1.39921927783199 0.287222602103888 0.613134644859584 GO:0043178 alcohol binding 3/385 92/18639 0.0326086956521739 1.57868435911914 0.295990608863144 0.613134644859584 GO:0004550 nucleoside diphosphate kinase activity 1/385 17/18639 0.0588235294117647 2.84782276546982 0.298810233996927 0.613134644859584 GO:0004659 prenyltransferase activity 1/385 17/18639 0.0588235294117647 2.84782276546982 0.298810233996927 0.613134644859584 GO:0030169 low-density lipoprotein particle binding 1/385 17/18639 0.0588235294117647 2.84782276546982 0.298810233996927 0.613134644859584 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/385 17/18639 0.0588235294117647 2.84782276546982 0.298810233996927 0.613134644859584 GO:0032183 SUMO binding 1/385 17/18639 0.0588235294117647 2.84782276546982 0.298810233996927 0.613134644859584 GO:0032977 membrane insertase activity 1/385 17/18639 0.0588235294117647 2.84782276546982 0.298810233996927 0.613134644859584 GO:0036041 long-chain fatty acid binding 1/385 17/18639 0.0588235294117647 2.84782276546982 0.298810233996927 0.613134644859584 GO:0046965 nuclear retinoid X receptor binding 1/385 17/18639 0.0588235294117647 2.84782276546982 0.298810233996927 0.613134644859584 GO:0048038 quinone binding 1/385 17/18639 0.0588235294117647 2.84782276546982 0.298810233996927 0.613134644859584 GO:0051787 misfolded protein binding 1/385 17/18639 0.0588235294117647 2.84782276546982 0.298810233996927 0.613134644859584 GO:0070492 oligosaccharide binding 1/385 17/18639 0.0588235294117647 2.84782276546982 0.298810233996927 0.613134644859584 GO:0017046 peptide hormone binding 2/385 53/18639 0.0377358490566038 1.8269051703014 0.299437849815146 0.613134644859584 GO:0140296 general transcription initiation factor binding 2/385 53/18639 0.0377358490566038 1.8269051703014 0.299437849815146 0.613134644859584 GO:0051219 phosphoprotein binding 3/385 93/18639 0.032258064516129 1.56170925848345 0.301641455480321 0.615814010001366 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/385 54/18639 0.037037037037037 1.79307359307359 0.307087868655258 0.61865274748747 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/385 54/18639 0.037037037037037 1.79307359307359 0.307087868655258 0.61865274748747 GO:0005319 lipid transporter activity 5/385 178/18639 0.0280898876404494 1.35991536553334 0.307302065468534 0.61865274748747 GO:0016779 nucleotidyltransferase activity 4/385 136/18639 0.0294117647058824 1.42391138273491 0.3094722108144 0.61865274748747 GO:0030695 GTPase regulator activity 12/385 489/18639 0.0245398773006135 1.1880487610549 0.312200685405933 0.61865274748747 GO:0004867 serine-type endopeptidase inhibitor activity 3/385 95/18639 0.0315789473684211 1.52883116883117 0.312957554023562 0.61865274748747 GO:0016854 racemase and epimerase activity 1/385 18/18639 0.0555555555555556 2.68961038961039 0.313306961518738 0.61865274748747 GO:0022851 GABA-gated chloride ion channel activity 1/385 18/18639 0.0555555555555556 2.68961038961039 0.313306961518738 0.61865274748747 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/385 18/18639 0.0555555555555556 2.68961038961039 0.313306961518738 0.61865274748747 GO:0098641 cadherin binding involved in cell-cell adhesion 1/385 18/18639 0.0555555555555556 2.68961038961039 0.313306961518738 0.61865274748747 GO:1901611 phosphatidylglycerol binding 1/385 18/18639 0.0555555555555556 2.68961038961039 0.313306961518738 0.61865274748747 GO:0060589 nucleoside-triphosphatase regulator activity 12/385 490/18639 0.0244897959183673 1.18562417174662 0.314623928053887 0.61865274748747 GO:0008374 O-acyltransferase activity 2/385 55/18639 0.0363636363636364 1.76047225501771 0.314721601192753 0.61865274748747 GO:0051020 GTPase binding 8/385 315/18639 0.0253968253968254 1.22953617810761 0.326779208805878 0.631786430189911 GO:0004890 GABA-A receptor activity 1/385 19/18639 0.0526315789473684 2.54805194805195 0.327504739286596 0.631786430189911 GO:0034987 immunoglobulin receptor binding 1/385 19/18639 0.0526315789473684 2.54805194805195 0.327504739286596 0.631786430189911 GO:0050145 nucleoside monophosphate kinase activity 1/385 19/18639 0.0526315789473684 2.54805194805195 0.327504739286596 0.631786430189911 GO:0140036 ubiquitin-modified protein reader activity 1/385 19/18639 0.0526315789473684 2.54805194805195 0.327504739286596 0.631786430189911 GO:1990380 K48-linked deubiquitinase activity 1/385 19/18639 0.0526315789473684 2.54805194805195 0.327504739286596 0.631786430189911 GO:0004175 endopeptidase activity 10/385 405/18639 0.0246913580246914 1.1953823953824 0.327831040084009 0.631786430189911 GO:0004725 protein tyrosine phosphatase activity 3/385 98/18639 0.0306122448979592 1.48203021468328 0.329948222934638 0.634090439606232 GO:0008237 metallopeptidase activity 5/385 184/18639 0.0271739130434783 1.31557029926595 0.331649123826871 0.635583836191887 GO:0042578 phosphoric ester hydrolase activity 9/385 363/18639 0.0247933884297521 1.20032199205753 0.336307793068225 0.640026934439993 GO:0020037 heme binding 4/385 142/18639 0.028169014084507 1.36374611304189 0.33754048180156 0.640026934439993 GO:0000339 RNA cap binding 1/385 20/18639 0.05 2.42064935064935 0.341409716481799 0.640026934439993 GO:0001972 retinoic acid binding 1/385 20/18639 0.05 2.42064935064935 0.341409716481799 0.640026934439993 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/385 20/18639 0.05 2.42064935064935 0.341409716481799 0.640026934439993 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/385 20/18639 0.05 2.42064935064935 0.341409716481799 0.640026934439993 GO:0042288 MHC class I protein binding 1/385 20/18639 0.05 2.42064935064935 0.341409716481799 0.640026934439993 GO:0061608 nuclear import signal receptor activity 1/385 20/18639 0.05 2.42064935064935 0.341409716481799 0.640026934439993 GO:0008234 cysteine-type peptidase activity 5/385 187/18639 0.0267379679144385 1.29446489339537 0.343893937459692 0.641594623927732 GO:0008017 microtubule binding 7/385 276/18639 0.0253623188405797 1.22786561264822 0.344890528183402 0.641594623927732 GO:0001786 phosphatidylserine binding 2/385 59/18639 0.0338983050847458 1.64111820383007 0.345043620426251 0.641594623927732 GO:0019955 cytokine binding 4/385 144/18639 0.0277777777777778 1.34480519480519 0.346924640540656 0.643353511299114 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/385 21/18639 0.0476190476190476 2.30538033395176 0.355027916124878 0.644236403972731 GO:0005123 death receptor binding 1/385 21/18639 0.0476190476190476 2.30538033395176 0.355027916124878 0.644236403972731 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/385 21/18639 0.0476190476190476 2.30538033395176 0.355027916124878 0.644236403972731 GO:0009975 cyclase activity 1/385 21/18639 0.0476190476190476 2.30538033395176 0.355027916124878 0.644236403972731 GO:0010314 phosphatidylinositol-5-phosphate binding 1/385 21/18639 0.0476190476190476 2.30538033395176 0.355027916124878 0.644236403972731 GO:0035613 RNA stem-loop binding 1/385 21/18639 0.0476190476190476 2.30538033395176 0.355027916124878 0.644236403972731 GO:0036122 BMP binding 1/385 21/18639 0.0476190476190476 2.30538033395176 0.355027916124878 0.644236403972731 GO:0072542 protein phosphatase activator activity 1/385 21/18639 0.0476190476190476 2.30538033395176 0.355027916124878 0.644236403972731 GO:0005253 monoatomic anion channel activity 3/385 103/18639 0.029126213592233 1.41008700037826 0.358228104672888 0.644236403972731 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/385 61/18639 0.0327868852459016 1.58731104960613 0.360044883516323 0.644236403972731 GO:0005243 gap junction channel activity 1/385 22/18639 0.0454545454545455 2.20059031877214 0.36836523765737 0.644236403972731 GO:0008649 rRNA methyltransferase activity 1/385 22/18639 0.0454545454545455 2.20059031877214 0.36836523765737 0.644236403972731 GO:0031683 G-protein beta/gamma-subunit complex binding 1/385 22/18639 0.0454545454545455 2.20059031877214 0.36836523765737 0.644236403972731 GO:0034062 5'-3' RNA polymerase activity 1/385 22/18639 0.0454545454545455 2.20059031877214 0.36836523765737 0.644236403972731 GO:0050321 tau-protein kinase activity 1/385 22/18639 0.0454545454545455 2.20059031877214 0.36836523765737 0.644236403972731 GO:0097747 RNA polymerase activity 1/385 22/18639 0.0454545454545455 2.20059031877214 0.36836523765737 0.644236403972731 GO:0140035 ubiquitin-like protein reader activity 1/385 22/18639 0.0454545454545455 2.20059031877214 0.36836523765737 0.644236403972731 GO:0031267 small GTPase binding 7/385 283/18639 0.0247349823321555 1.19749437841311 0.368417255341932 0.644236403972731 GO:0035091 phosphatidylinositol binding 7/385 284/18639 0.0246478873239437 1.19327784891165 0.371788699918415 0.644236403972731 GO:0005507 copper ion binding 2/385 63/18639 0.0317460317460317 1.53692022263451 0.374917706800967 0.644236403972731 GO:0019842 vitamin binding 4/385 150/18639 0.0266666666666667 1.29101298701299 0.375082089275031 0.644236403972731 GO:0000510 H3-H4 histone complex chaperone activity 4/385 151/18639 0.0264900662251656 1.28246323213211 0.379768659960297 0.644236403972731 GO:0140584 chromatin extrusion motor activity 4/385 151/18639 0.0264900662251656 1.28246323213211 0.379768659960297 0.644236403972731 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 4/385 151/18639 0.0264900662251656 1.28246323213211 0.379768659960297 0.644236403972731 GO:0140849 ATP-dependent H2AZ histone chaperone activity 4/385 151/18639 0.0264900662251656 1.28246323213211 0.379768659960297 0.644236403972731 GO:0003887 DNA-directed DNA polymerase activity 1/385 23/18639 0.0434782608695652 2.10491247882552 0.381427459470869 0.644236403972731 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/385 23/18639 0.0434782608695652 2.10491247882552 0.381427459470869 0.644236403972731 GO:0004602 glutathione peroxidase activity 1/385 23/18639 0.0434782608695652 2.10491247882552 0.381427459470869 0.644236403972731 GO:0008171 O-methyltransferase activity 1/385 23/18639 0.0434782608695652 2.10491247882552 0.381427459470869 0.644236403972731 GO:0016917 GABA receptor activity 1/385 23/18639 0.0434782608695652 2.10491247882552 0.381427459470869 0.644236403972731 GO:0017134 fibroblast growth factor binding 1/385 23/18639 0.0434782608695652 2.10491247882552 0.381427459470869 0.644236403972731 GO:0031681 G-protein beta-subunit binding 1/385 23/18639 0.0434782608695652 2.10491247882552 0.381427459470869 0.644236403972731 GO:0042171 lysophosphatidic acid acyltransferase activity 1/385 23/18639 0.0434782608695652 2.10491247882552 0.381427459470869 0.644236403972731 GO:0071617 lysophospholipid acyltransferase activity 1/385 23/18639 0.0434782608695652 2.10491247882552 0.381427459470869 0.644236403972731 GO:0140102 catalytic activity, acting on a rRNA 1/385 23/18639 0.0434782608695652 2.10491247882552 0.381427459470869 0.644236403972731 GO:0015616 DNA translocase activity 4/385 152/18639 0.0263157894736842 1.27402597402597 0.384451690313483 0.644236403972731 GO:0046906 tetrapyrrole binding 4/385 152/18639 0.0263157894736842 1.27402597402597 0.384451690313483 0.644236403972731 GO:0140674 ATP-dependent histone chaperone activity 4/385 152/18639 0.0263157894736842 1.27402597402597 0.384451690313483 0.644236403972731 GO:0005496 steroid binding 3/385 108/18639 0.0277777777777778 1.34480519480519 0.386337777534211 0.644236403972731 GO:0061775 cohesin loader activity 4/385 153/18639 0.0261437908496732 1.26569900687548 0.38913055372353 0.644236403972731 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/385 24/18639 0.0416666666666667 2.01720779220779 0.394220241384476 0.644236403972731 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/385 24/18639 0.0416666666666667 2.01720779220779 0.394220241384476 0.644236403972731 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/385 24/18639 0.0416666666666667 2.01720779220779 0.394220241384476 0.644236403972731 GO:0004622 lysophospholipase activity 1/385 24/18639 0.0416666666666667 2.01720779220779 0.394220241384476 0.644236403972731 GO:0004806 triacylglycerol lipase activity 1/385 24/18639 0.0416666666666667 2.01720779220779 0.394220241384476 0.644236403972731 GO:0005540 hyaluronic acid binding 1/385 24/18639 0.0416666666666667 2.01720779220779 0.394220241384476 0.644236403972731 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/385 24/18639 0.0416666666666667 2.01720779220779 0.394220241384476 0.644236403972731 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/385 24/18639 0.0416666666666667 2.01720779220779 0.394220241384476 0.644236403972731 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/385 24/18639 0.0416666666666667 2.01720779220779 0.394220241384476 0.644236403972731 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/385 24/18639 0.0416666666666667 2.01720779220779 0.394220241384476 0.644236403972731 GO:0008235 metalloexopeptidase activity 2/385 66/18639 0.0303030303030303 1.46706021251476 0.39695464316963 0.644800459505309 GO:0015631 tubulin binding 9/385 385/18639 0.0233766233766234 1.13173216393996 0.400629604248892 0.644800459505309 GO:0042393 histone binding 6/385 247/18639 0.0242914979757085 1.17602397602398 0.402194898557281 0.644800459505309 GO:0004674 protein serine/threonine kinase activity 10/385 433/18639 0.023094688221709 1.11808284094658 0.404989122301922 0.644800459505309 GO:0003707 nuclear steroid receptor activity 1/385 25/18639 0.04 1.93651948051948 0.406749127071663 0.644800459505309 GO:0008483 transaminase activity 1/385 25/18639 0.04 1.93651948051948 0.406749127071663 0.644800459505309 GO:0015662 P-type ion transporter activity 1/385 25/18639 0.04 1.93651948051948 0.406749127071663 0.644800459505309 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/385 25/18639 0.04 1.93651948051948 0.406749127071663 0.644800459505309 GO:0017025 TBP-class protein binding 1/385 25/18639 0.04 1.93651948051948 0.406749127071663 0.644800459505309 GO:0019211 phosphatase activator activity 1/385 25/18639 0.04 1.93651948051948 0.406749127071663 0.644800459505309 GO:0042974 nuclear retinoic acid receptor binding 1/385 25/18639 0.04 1.93651948051948 0.406749127071663 0.644800459505309 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/385 25/18639 0.04 1.93651948051948 0.406749127071663 0.644800459505309 GO:0140358 P-type transmembrane transporter activity 1/385 25/18639 0.04 1.93651948051948 0.406749127071663 0.644800459505309 GO:0005548 phospholipid transporter activity 2/385 68/18639 0.0294117647058824 1.42391138273491 0.411445684993211 0.644933888029224 GO:0140658 ATP-dependent chromatin remodeler activity 4/385 158/18639 0.0253164556962025 1.22564524083511 0.412441131315361 0.644933888029224 GO:0008168 methyltransferase activity 5/385 204/18639 0.0245098039215686 1.18659281894576 0.413480858999644 0.644933888029224 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 11/385 484/18639 0.0227272727272727 1.10029515938607 0.416570509985283 0.644933888029224 GO:0016279 protein-lysine N-methyltransferase activity 2/385 69/18639 0.0289855072463768 1.40327498588368 0.418626802958738 0.644933888029224 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/385 26/18639 0.0384615384615385 1.86203796203796 0.419019546437592 0.644933888029224 GO:0008143 poly(A) binding 1/385 26/18639 0.0384615384615385 1.86203796203796 0.419019546437592 0.644933888029224 GO:0008198 ferrous iron binding 1/385 26/18639 0.0384615384615385 1.86203796203796 0.419019546437592 0.644933888029224 GO:0030247 polysaccharide binding 1/385 26/18639 0.0384615384615385 1.86203796203796 0.419019546437592 0.644933888029224 GO:0051139 metal cation:proton antiporter activity 1/385 26/18639 0.0384615384615385 1.86203796203796 0.419019546437592 0.644933888029224 GO:0070006 metalloaminopeptidase activity 1/385 26/18639 0.0384615384615385 1.86203796203796 0.419019546437592 0.644933888029224 GO:0070412 R-SMAD binding 1/385 26/18639 0.0384615384615385 1.86203796203796 0.419019546437592 0.644933888029224 GO:0097602 cullin family protein binding 1/385 26/18639 0.0384615384615385 1.86203796203796 0.419019546437592 0.644933888029224 GO:0003689 DNA clamp loader activity 4/385 160/18639 0.025 1.21032467532468 0.421715379504101 0.647634332809869 GO:0101005 deubiquitinase activity 3/385 115/18639 0.0260869565217391 1.26294748729531 0.42516536734336 0.648913196385474 GO:0016278 lysine N-methyltransferase activity 2/385 70/18639 0.0285714285714286 1.38322820037106 0.425763239398199 0.648913196385474 GO:0016782 transferase activity, transferring sulphur-containing groups 2/385 70/18639 0.0285714285714286 1.38322820037106 0.425763239398199 0.648913196385474 GO:0008083 growth factor activity 4/385 162/18639 0.0246913580246914 1.1953823953824 0.430954358682053 0.648913196385474 GO:0001671 ATPase activator activity 1/385 27/18639 0.037037037037037 1.79307359307359 0.431036817947909 0.648913196385474 GO:0004364 glutathione transferase activity 1/385 27/18639 0.037037037037037 1.79307359307359 0.431036817947909 0.648913196385474 GO:0005044 scavenger receptor activity 1/385 27/18639 0.037037037037037 1.79307359307359 0.431036817947909 0.648913196385474 GO:0005385 zinc ion transmembrane transporter activity 1/385 27/18639 0.037037037037037 1.79307359307359 0.431036817947909 0.648913196385474 GO:0015252 proton channel activity 1/385 27/18639 0.037037037037037 1.79307359307359 0.431036817947909 0.648913196385474 GO:0140299 molecular sensor activity 2/385 71/18639 0.028169014084507 1.36374611304189 0.432853774672559 0.650225757586727 GO:0001216 DNA-binding transcription activator activity 11/385 491/18639 0.0224032586558045 1.08460867035205 0.435088576685015 0.652158912329608 GO:0008094 ATP-dependent activity, acting on DNA 5/385 210/18639 0.0238095238095238 1.15269016697588 0.437859986899835 0.654886241276275 GO:0019789 SUMO transferase activity 1/385 28/18639 0.0357142857142857 1.72903525046382 0.442806150909979 0.656574637556176 GO:0046966 nuclear thyroid hormone receptor binding 1/385 28/18639 0.0357142857142857 1.72903525046382 0.442806150909979 0.656574637556176 GO:0051019 mitogen-activated protein kinase binding 1/385 28/18639 0.0357142857142857 1.72903525046382 0.442806150909979 0.656574637556176 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/385 28/18639 0.0357142857142857 1.72903525046382 0.442806150909979 0.656574637556176 GO:0015103 inorganic anion transmembrane transporter activity 4/385 165/18639 0.0242424242424242 1.17364817001181 0.444737447950621 0.657967966651293 GO:0003712 transcription coregulator activity 11/385 495/18639 0.0222222222222222 1.07584415584416 0.445658535551603 0.657967966651293 GO:0035064 methylated histone binding 2/385 74/18639 0.027027027027027 1.30845910845911 0.453838800392867 0.666483713481444 GO:0004181 metallocarboxypeptidase activity 1/385 29/18639 0.0344827586206897 1.66941334527541 0.454332647707554 0.666483713481444 GO:0051861 glycolipid binding 1/385 29/18639 0.0344827586206897 1.66941334527541 0.454332647707554 0.666483713481444 GO:0004540 RNA nuclease activity 3/385 121/18639 0.0247933884297521 1.20032199205753 0.45775448020234 0.667595003061151 GO:0015108 chloride transmembrane transporter activity 3/385 121/18639 0.0247933884297521 1.20032199205753 0.45775448020234 0.667595003061151 GO:0016741 transferase activity, transferring one-carbon groups 5/385 215/18639 0.0232558139534884 1.12588341890667 0.458001223030325 0.667595003061151 GO:0019003 GDP binding 2/385 75/18639 0.0266666666666667 1.29101298701299 0.460734883034327 0.670159829868112 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/385 122/18639 0.0245901639344262 1.1904832872046 0.463111542030073 0.671587963356357 GO:0001965 G-protein alpha-subunit binding 1/385 30/18639 0.0333333333333333 1.61376623376623 0.4656213059898 0.671587963356357 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/385 30/18639 0.0333333333333333 1.61376623376623 0.4656213059898 0.671587963356357 GO:0016769 transferase activity, transferring nitrogenous groups 1/385 30/18639 0.0333333333333333 1.61376623376623 0.4656213059898 0.671587963356357 GO:0140034 methylation-dependent protein binding 2/385 76/18639 0.0263157894736842 1.27402597402597 0.467579957988923 0.673002115264391 GO:0106310 protein serine kinase activity 8/385 361/18639 0.0221606648199446 1.07286397812714 0.470336754585869 0.675556758152563 GO:0003724 RNA helicase activity 2/385 77/18639 0.025974025974026 1.25748018215551 0.474373186930558 0.679934901267133 GO:0047499 calcium-independent phospholipase A2 activity 1/385 31/18639 0.032258064516129 1.56170925848345 0.476677020815633 0.680402054608206 GO:0070273 phosphatidylinositol-4-phosphate binding 1/385 31/18639 0.032258064516129 1.56170925848345 0.476677020815633 0.680402054608206 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 6/385 268/18639 0.0223880597014925 1.08387284357434 0.478788639661407 0.682001209289955 GO:0031369 translation initiation factor binding 1/385 32/18639 0.03125 1.51290584415584 0.48750458675426 0.68316942650371 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/385 32/18639 0.03125 1.51290584415584 0.48750458675426 0.68316942650371 GO:0047498 calcium-dependent phospholipase A2 activity 1/385 32/18639 0.03125 1.51290584415584 0.48750458675426 0.68316942650371 GO:0070717 poly-purine tract binding 1/385 32/18639 0.03125 1.51290584415584 0.48750458675426 0.68316942650371 GO:0071813 lipoprotein particle binding 1/385 32/18639 0.03125 1.51290584415584 0.48750458675426 0.68316942650371 GO:0071814 protein-lipid complex binding 1/385 32/18639 0.03125 1.51290584415584 0.48750458675426 0.68316942650371 GO:0140142 nucleocytoplasmic carrier activity 1/385 32/18639 0.03125 1.51290584415584 0.48750458675426 0.68316942650371 GO:0008186 ATP-dependent activity, acting on RNA 2/385 79/18639 0.0253164556962025 1.22564524083511 0.487801032335401 0.68316942650371 GO:0005096 GTPase activator activity 6/385 271/18639 0.022140221402214 1.07187425121004 0.489527052107302 0.68316942650371 GO:0019783 ubiquitin-like protein peptidase activity 3/385 127/18639 0.0236220472440945 1.14361386644851 0.489538557073153 0.68316942650371 GO:0016887 ATP hydrolysis activity 9/385 417/18639 0.0215827338129496 1.04488461179109 0.494229890047383 0.687031414265663 GO:0004252 serine-type endopeptidase activity 4/385 176/18639 0.0227272727272727 1.10029515938607 0.494303125089394 0.687031414265663 GO:0030296 protein tyrosine kinase activator activity 1/385 33/18639 0.0303030303030303 1.46706021251476 0.498108699942824 0.690924970888434 GO:0015035 protein-disulfide reductase activity 1/385 34/18639 0.0294117647058824 1.42391138273491 0.508493960102021 0.701089868838057 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/385 34/18639 0.0294117647058824 1.42391138273491 0.508493960102021 0.701089868838057 GO:0090482 vitamin transmembrane transporter activity 1/385 34/18639 0.0294117647058824 1.42391138273491 0.508493960102021 0.701089868838057 GO:0031072 heat shock protein binding 3/385 131/18639 0.0229007633587786 1.10869435907604 0.510216021022967 0.702057244927602 GO:0016853 isomerase activity 4/385 180/18639 0.0222222222222222 1.07584415584416 0.511870184213631 0.702443764344999 GO:0001217 DNA-binding transcription repressor activity 6/385 278/18639 0.0215827338129496 1.04488461179109 0.514294697394813 0.702443764344999 GO:0005179 hormone activity 3/385 132/18639 0.0227272727272727 1.10029515938607 0.515316627105516 0.702443764344999 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 3/385 132/18639 0.0227272727272727 1.10029515938607 0.515316627105516 0.702443764344999 GO:0004623 phospholipase A2 activity 1/385 35/18639 0.0285714285714286 1.38322820037106 0.518664872510552 0.702443764344999 GO:0016229 steroid dehydrogenase activity 1/385 35/18639 0.0285714285714286 1.38322820037106 0.518664872510552 0.702443764344999 GO:0034061 DNA polymerase activity 1/385 35/18639 0.0285714285714286 1.38322820037106 0.518664872510552 0.702443764344999 GO:0061631 ubiquitin conjugating enzyme activity 1/385 35/18639 0.0285714285714286 1.38322820037106 0.518664872510552 0.702443764344999 GO:0004527 exonuclease activity 2/385 84/18639 0.0238095238095238 1.15269016697588 0.520414995908179 0.703228992339099 GO:0030246 carbohydrate binding 6/385 280/18639 0.0214285714285714 1.03742115027829 0.521288933274622 0.703228992339099 GO:0051087 protein-folding chaperone binding 3/385 134/18639 0.0223880597014925 1.08387284357434 0.5254321197215 0.707431112266912 GO:0004033 aldo-keto reductase (NADPH) activity 1/385 36/18639 0.0277777777777778 1.34480519480519 0.528625849939247 0.707577013148252 GO:0005484 SNAP receptor activity 1/385 36/18639 0.0277777777777778 1.34480519480519 0.528625849939247 0.707577013148252 GO:0055106 ubiquitin-protein transferase regulator activity 1/385 36/18639 0.0277777777777778 1.34480519480519 0.528625849939247 0.707577013148252 GO:0005125 cytokine activity 5/385 234/18639 0.0213675213675214 1.03446553446553 0.532321563557834 0.711140263549106 GO:0008081 phosphoric diester hydrolase activity 2/385 87/18639 0.0229885057471264 1.11294223018361 0.539307253090823 0.718947001241029 GO:0140097 catalytic activity, acting on DNA 7/385 336/18639 0.0208333333333333 1.0086038961039 0.544101425075556 0.718947001241029 GO:0000146 microfilament motor activity 1/385 38/18639 0.0263157894736842 1.27402597402597 0.54793519973006 0.718947001241029 GO:0043531 ADP binding 1/385 38/18639 0.0263157894736842 1.27402597402597 0.54793519973006 0.718947001241029 GO:0140098 catalytic activity, acting on RNA 8/385 387/18639 0.020671834625323 1.00078526125038 0.549056233185966 0.718947001241029 GO:0019902 phosphatase binding 4/385 190/18639 0.0210526315789474 1.01922077922078 0.554508657432299 0.718947001241029 GO:0000217 DNA secondary structure binding 1/385 39/18639 0.0256410256410256 1.24135864135864 0.55729195195327 0.718947001241029 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 5/385 243/18639 0.0205761316872428 0.996151996151996 0.565908558570211 0.718947001241029 GO:0004177 aminopeptidase activity 1/385 40/18639 0.025 1.21032467532468 0.566455532517678 0.718947001241029 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/385 40/18639 0.025 1.21032467532468 0.566455532517678 0.718947001241029 GO:0071855 neuropeptide receptor binding 1/385 40/18639 0.025 1.21032467532468 0.566455532517678 0.718947001241029 GO:0008236 serine-type peptidase activity 4/385 194/18639 0.0206185567010309 0.998205917793547 0.571002235408298 0.718947001241029 GO:0004676 3-phosphoinositide-dependent protein kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0004711 ribosomal protein S6 kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0035175 histone H3S10 kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0035979 histone H2AXS139 kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0044022 histone H3S28 kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0044023 histone H4S1 kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0044024 histone H2AS1 kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0044025 histone H2BS14 kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0072354 histone H3T3 kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0072371 histone H2AS121 kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0072518 Rho-dependent protein serine/threonine kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0140823 histone H2BS36 kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0140855 histone H3S57 kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0140995 histone H2A kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0140997 histone H4 kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0140998 histone H2B kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:1990244 histone H2AT120 kinase activity 5/385 245/18639 0.0204081632653061 0.988020143122184 0.57320520605875 0.718947001241029 GO:0001530 lipopolysaccharide binding 1/385 41/18639 0.024390243902439 1.18080456129237 0.575429919311629 0.718947001241029 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/385 41/18639 0.024390243902439 1.18080456129237 0.575429919311629 0.718947001241029 GO:0042169 SH2 domain binding 1/385 41/18639 0.024390243902439 1.18080456129237 0.575429919311629 0.718947001241029 GO:0042287 MHC protein binding 1/385 41/18639 0.024390243902439 1.18080456129237 0.575429919311629 0.718947001241029 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/385 41/18639 0.024390243902439 1.18080456129237 0.575429919311629 0.718947001241029 GO:0140828 metal cation:monoatomic cation antiporter activity 1/385 41/18639 0.024390243902439 1.18080456129237 0.575429919311629 0.718947001241029 GO:0004677 DNA-dependent protein kinase activity 5/385 246/18639 0.0203252032520325 0.984003801076972 0.576829570763151 0.718947001241029 GO:0140857 histone H3T45 kinase activity 5/385 246/18639 0.0203252032520325 0.984003801076972 0.576829570763151 0.718947001241029 GO:0033218 amide binding 5/385 247/18639 0.0202429149797571 0.98001998001998 0.58043772514757 0.719377287957706 GO:0035402 histone H3T11 kinase activity 5/385 247/18639 0.0202429149797571 0.98001998001998 0.58043772514757 0.719377287957706 GO:0035403 histone H3T6 kinase activity 5/385 247/18639 0.0202429149797571 0.98001998001998 0.58043772514757 0.719377287957706 GO:0042562 hormone binding 2/385 94/18639 0.0212765957446809 1.03006355346781 0.581357226896053 0.719377287957706 GO:0004679 AMP-activated protein kinase activity 5/385 248/18639 0.0201612903225806 0.976068286552157 0.584029497237314 0.720327379678434 GO:0004520 DNA endonuclease activity 1/385 42/18639 0.0238095238095238 1.15269016697588 0.584219008518265 0.720327379678434 GO:0017171 serine hydrolase activity 4/385 198/18639 0.0202020202020202 0.978040141676505 0.587150734298202 0.722647057597787 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/385 43/18639 0.0232558139534884 1.12588341890667 0.592826616289436 0.728329842869878 GO:0016829 lyase activity 4/385 200/18639 0.02 0.96825974025974 0.595091399124712 0.729809059889129 GO:0008509 monoatomic anion transmembrane transporter activity 3/385 149/18639 0.0201342281879195 0.974758127778262 0.597377914646489 0.731309617930221 GO:0001046 core promoter sequence-specific DNA binding 1/385 44/18639 0.0227272727272727 1.10029515938607 0.601256480385401 0.733447621463042 GO:0001223 transcription coactivator binding 1/385 44/18639 0.0227272727272727 1.10029515938607 0.601256480385401 0.733447621463042 GO:0042626 ATPase-coupled transmembrane transporter activity 2/385 98/18639 0.0204081632653061 0.988020143122184 0.604090823054682 0.735152579797526 GO:0022804 active transmembrane transporter activity 9/385 457/18639 0.0196936542669584 0.953428628264515 0.604791221170639 0.735152579797526 GO:0003713 transcription coactivator activity 5/385 256/18639 0.01953125 0.945566152597403 0.612154889548088 0.742422651816432 GO:0003774 cytoskeletal motor activity 3/385 153/18639 0.0196078431372549 0.949274255156608 0.615321753932091 0.742422651816432 GO:0004180 carboxypeptidase activity 1/385 46/18639 0.0217391304347826 1.05245623941276 0.617597546239146 0.742422651816432 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/385 46/18639 0.0217391304347826 1.05245623941276 0.617597546239146 0.742422651816432 GO:0030276 clathrin binding 1/385 46/18639 0.0217391304347826 1.05245623941276 0.617597546239146 0.742422651816432 GO:0005506 iron ion binding 3/385 154/18639 0.0194805194805195 0.94311013661663 0.61972275632507 0.742422651816432 GO:0004386 helicase activity 3/385 155/18639 0.0193548387096774 0.937025555090071 0.624089521459423 0.742422651816432 GO:0001784 phosphotyrosine residue binding 1/385 47/18639 0.0212765957446809 1.03006355346781 0.625515845851792 0.742422651816432 GO:0043495 protein-membrane adaptor activity 1/385 47/18639 0.0212765957446809 1.03006355346781 0.625515845851792 0.742422651816432 GO:0061749 forked DNA-dependent helicase activity 1/385 47/18639 0.0212765957446809 1.03006355346781 0.625515845851792 0.742422651816432 GO:0099095 ligand-gated monoatomic anion channel activity 1/385 47/18639 0.0212765957446809 1.03006355346781 0.625515845851792 0.742422651816432 GO:0140938 histone H3 methyltransferase activity 1/385 47/18639 0.0212765957446809 1.03006355346781 0.625515845851792 0.742422651816432 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/385 47/18639 0.0212765957446809 1.03006355346781 0.625515845851792 0.742422651816432 GO:0008238 exopeptidase activity 2/385 102/18639 0.0196078431372549 0.949274255156608 0.625879561124318 0.742422651816432 GO:0009378 four-way junction helicase activity 1/385 48/18639 0.0208333333333333 1.0086038961039 0.633270600549891 0.746044817086173 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/385 48/18639 0.0208333333333333 1.0086038961039 0.633270600549891 0.746044817086173 GO:0036121 double-stranded DNA helicase activity 1/385 48/18639 0.0208333333333333 1.0086038961039 0.633270600549891 0.746044817086173 GO:0043138 3'-5' DNA helicase activity 1/385 48/18639 0.0208333333333333 1.0086038961039 0.633270600549891 0.746044817086173 GO:0046982 protein heterodimerization activity 7/385 369/18639 0.018970189701897 0.91840354767184 0.642724682640713 0.755888173772326 GO:0008013 beta-catenin binding 2/385 106/18639 0.0188679245283019 0.913452585150698 0.646728564596347 0.759299065601172 GO:0032813 tumor necrosis factor receptor superfamily binding 1/385 50/18639 0.02 0.96825974025974 0.648302882963562 0.759850738464958 GO:0004843 cysteine-type deubiquitinase activity 2/385 108/18639 0.0185185185185185 0.896536796536796 0.656803721899989 0.768505035148286 GO:0004620 phospholipase activity 2/385 109/18639 0.018348623853211 0.888311688311688 0.661754673962988 0.770498713289239 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/385 52/18639 0.0192307692307692 0.931018981018981 0.662720525151245 0.770498713289239 GO:0004222 metalloendopeptidase activity 2/385 110/18639 0.0181818181818182 0.880236127508855 0.666648188510224 0.770498713289239 GO:0004864 protein phosphatase inhibitor activity 1/385 53/18639 0.0188679245283019 0.913452585150698 0.66970673044617 0.770498713289239 GO:0005246 calcium channel regulator activity 1/385 53/18639 0.0188679245283019 0.913452585150698 0.66970673044617 0.770498713289239 GO:0005544 calcium-dependent phospholipid binding 1/385 53/18639 0.0188679245283019 0.913452585150698 0.66970673044617 0.770498713289239 GO:0008146 sulfotransferase activity 1/385 53/18639 0.0188679245283019 0.913452585150698 0.66970673044617 0.770498713289239 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/385 53/18639 0.0188679245283019 0.913452585150698 0.66970673044617 0.770498713289239 GO:0051018 protein kinase A binding 1/385 53/18639 0.0188679245283019 0.913452585150698 0.66970673044617 0.770498713289239 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/385 53/18639 0.0188679245283019 0.913452585150698 0.66970673044617 0.770498713289239 GO:1902936 phosphatidylinositol bisphosphate binding 2/385 111/18639 0.018018018018018 0.872306072306072 0.671484519284129 0.771254339344709 GO:0016874 ligase activity 3/385 167/18639 0.0179640718562874 0.869694377478809 0.673792387482542 0.771916142429403 GO:0015485 cholesterol binding 1/385 54/18639 0.0185185185185185 0.896536796536796 0.67654859576298 0.771916142429403 GO:0050661 NADP binding 1/385 54/18639 0.0185185185185185 0.896536796536796 0.67654859576298 0.771916142429403 GO:0051287 NAD binding 1/385 54/18639 0.0185185185185185 0.896536796536796 0.67654859576298 0.771916142429403 GO:0019212 phosphatase inhibitor activity 1/385 56/18639 0.0178571428571429 0.864517625231911 0.689811143562233 0.781087707891949 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/385 56/18639 0.0178571428571429 0.864517625231911 0.689811143562233 0.781087707891949 GO:0170055 lipid transmembrane transporter activity 1/385 56/18639 0.0178571428571429 0.864517625231911 0.689811143562233 0.781087707891949 GO:0035401 histone H3Y41 kinase activity 2/385 115/18639 0.0173913043478261 0.841964991530209 0.69026355581149 0.781087707891949 GO:0140801 histone H2AXY142 kinase activity 2/385 115/18639 0.0173913043478261 0.841964991530209 0.69026355581149 0.781087707891949 GO:0017116 single-stranded DNA helicase activity 1/385 58/18639 0.0172413793103448 0.834706672637707 0.702531238814504 0.793664190975992 GO:0031593 polyubiquitin modification-dependent protein binding 1/385 59/18639 0.0169491525423729 0.820559101915034 0.708694818441888 0.796702671712449 GO:0036002 pre-mRNA binding 1/385 59/18639 0.0169491525423729 0.820559101915034 0.708694818441888 0.796702671712449 GO:0070888 E-box binding 1/385 59/18639 0.0169491525423729 0.820559101915034 0.708694818441888 0.796702671712449 GO:0001098 basal transcription machinery binding 1/385 60/18639 0.0166666666666667 0.806883116883117 0.714731013000546 0.80087123280843 GO:0001099 basal RNA polymerase II transcription machinery binding 1/385 60/18639 0.0166666666666667 0.806883116883117 0.714731013000546 0.80087123280843 GO:0015026 coreceptor activity 1/385 61/18639 0.0163934426229508 0.793655524803066 0.72064244849195 0.803568889080165 GO:0016836 hydro-lyase activity 1/385 61/18639 0.0163934426229508 0.793655524803066 0.72064244849195 0.803568889080165 GO:0019905 syntaxin binding 1/385 61/18639 0.0163934426229508 0.793655524803066 0.72064244849195 0.803568889080165 GO:0022824 transmitter-gated monoatomic ion channel activity 1/385 63/18639 0.0158730158730159 0.768460111317254 0.732101277407666 0.81239625622012 GO:0022835 transmitter-gated channel activity 1/385 63/18639 0.0158730158730159 0.768460111317254 0.732101277407666 0.81239625622012 GO:1901682 sulfur compound transmembrane transporter activity 1/385 63/18639 0.0158730158730159 0.768460111317254 0.732101277407666 0.81239625622012 GO:0004536 DNA nuclease activity 1/385 64/18639 0.015625 0.756452922077922 0.737653657263289 0.81723947857833 GO:0141003 histone H2AX kinase activity 6/385 354/18639 0.0169491525423729 0.820559101915034 0.742738666773362 0.820620838051976 GO:0120013 lipid transfer activity 1/385 65/18639 0.0153846153846154 0.744815184815185 0.7430912530616 0.820620838051976 GO:0031490 chromatin DNA binding 2/385 128/18639 0.015625 0.756452922077922 0.745257011913357 0.821693628519856 GO:0035591 signaling adaptor activity 2/385 129/18639 0.0155038759689922 0.750588945937783 0.749120408417023 0.824203686964329 GO:0140996 histone H3 kinase activity 6/385 357/18639 0.0168067226890756 0.813663647277093 0.749929517499521 0.824203686964329 GO:0016298 lipase activity 2/385 130/18639 0.0153846153846154 0.744815184815185 0.752933423639551 0.824663931367389 GO:0008173 RNA methyltransferase activity 1/385 67/18639 0.0149253731343284 0.722581895716224 0.753631511296547 0.824663931367389 GO:0035173 histone kinase activity 6/385 360/18639 0.0166666666666667 0.806883116883117 0.756974236761031 0.824663931367389 GO:0030145 manganese ion binding 1/385 68/18639 0.0147058823529412 0.711955691367456 0.758738762435403 0.824663931367389 GO:0032934 sterol binding 1/385 68/18639 0.0147058823529412 0.711955691367456 0.758738762435403 0.824663931367389 GO:0140223 general transcription initiation factor activity 1/385 68/18639 0.0147058823529412 0.711955691367456 0.758738762435403 0.824663931367389 GO:1990841 promoter-specific chromatin binding 1/385 68/18639 0.0147058823529412 0.711955691367456 0.758738762435403 0.824663931367389 GO:0098960 postsynaptic neurotransmitter receptor activity 1/385 69/18639 0.0144927536231884 0.701637492941841 0.763740408898295 0.828790853820232 GO:0015297 antiporter activity 2/385 135/18639 0.0148148148148148 0.717229437229437 0.771257840001282 0.835630541607688 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/385 73/18639 0.0136986301369863 0.66319160291763 0.782733842602343 0.846730949230208 GO:0140101 catalytic activity, acting on a tRNA 2/385 139/18639 0.0143884892086331 0.696589741194058 0.785054923590406 0.847908614490109 GO:0003678 DNA helicase activity 1/385 74/18639 0.0135135135135135 0.654229554229554 0.78723925413946 0.848843552064306 GO:0004713 protein tyrosine kinase activity 2/385 140/18639 0.0142857142857143 0.691614100185529 0.788388124664377 0.848843552064306 GO:0019903 protein phosphatase binding 2/385 144/18639 0.0138888888888889 0.672402597402597 0.801270193193718 0.861365457683247 GO:0016757 glycosyltransferase activity 4/385 267/18639 0.0149812734082397 0.725288194951116 0.804976004115569 0.863999205665384 GO:0015370 solute:sodium symporter activity 1/385 79/18639 0.0126582278481013 0.612822620417557 0.808406321411954 0.864982191495216 GO:0016835 carbon-oxygen lyase activity 1/385 79/18639 0.0126582278481013 0.612822620417557 0.808406321411954 0.864982191495216 GO:0015085 calcium ion transmembrane transporter activity 2/385 147/18639 0.0136054421768707 0.658680095414789 0.810471178307951 0.865844985521538 GO:0030971 receptor tyrosine kinase binding 1/385 81/18639 0.0123456790123457 0.597691197691198 0.816272749619428 0.870690932927389 GO:0001540 amyloid-beta binding 1/385 83/18639 0.0120481927710843 0.58328900015647 0.823817003505616 0.877377861318675 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/385 86/18639 0.0116279069767442 0.562941709453337 0.834557951853242 0.886073874807146 GO:0050660 flavin adenine dinucleotide binding 1/385 86/18639 0.0116279069767442 0.562941709453337 0.834557951853242 0.886073874807146 GO:0003727 single-stranded RNA binding 1/385 89/18639 0.0112359550561798 0.543966146213337 0.844645678135914 0.895402506251939 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/385 91/18639 0.010989010989011 0.532010846296561 0.851027598160296 0.900349513418557 GO:0052689 carboxylic ester hydrolase activity 1/385 92/18639 0.0108695652173913 0.526228119706381 0.854119811590762 0.900349513418557 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/385 229/18639 0.0131004366812227 0.634231270912494 0.85514980136221 0.900349513418557 GO:0015081 sodium ion transmembrane transporter activity 2/385 164/18639 0.0121951219512195 0.590402280646183 0.855767389652981 0.900349513418557 GO:0051213 dioxygenase activity 1/385 93/18639 0.010752688172043 0.520569752827817 0.857148003348866 0.900349513418557 GO:0005085 guanyl-nucleotide exchange factor activity 3/385 230/18639 0.0130434782608696 0.631473743647657 0.857164144315632 0.900349513418557 GO:0016410 N-acyltransferase activity 1/385 94/18639 0.0106382978723404 0.515031776733904 0.860113495568789 0.902070251450193 GO:0004896 cytokine receptor activity 1/385 96/18639 0.0104166666666667 0.504301948051948 0.86586153432016 0.906716492560532 GO:0030594 neurotransmitter receptor activity 1/385 97/18639 0.0103092783505155 0.499102958896773 0.868646591176479 0.908250539102459 GO:0061659 ubiquitin-like protein ligase activity 5/385 372/18639 0.0134408602150538 0.650712191034772 0.885786014949449 0.924765976153598 GO:0000149 SNARE binding 1/385 106/18639 0.00943396226415094 0.456726292575349 0.891254545003462 0.929065343882397 GO:0046873 metal ion transmembrane transporter activity 6/385 450/18639 0.0133333333333333 0.645506493506494 0.90619054147242 0.943205888854803 GO:0003730 mRNA 3'-UTR binding 3/385 262/18639 0.0114503816793893 0.554347179538019 0.90987657245411 0.94561190611545 GO:0015294 solute:monoatomic cation symporter activity 1/385 116/18639 0.00862068965517241 0.417353336318854 0.911850635706283 0.946234143840004 GO:1990782 protein tyrosine kinase binding 1/385 117/18639 0.00854700854700855 0.413786213786214 0.913682817601931 0.946707497756217 GO:0016758 hexosyltransferase activity 2/385 197/18639 0.0101522842639594 0.491502406223218 0.916682631929713 0.948387444763372 GO:0003697 single-stranded DNA binding 1/385 121/18639 0.00826446280991736 0.400107330685843 0.920639469683267 0.949902877034957 GO:0008528 G protein-coupled peptide receptor activity 1/385 122/18639 0.00819672131147541 0.396827762401533 0.922289421307197 0.949902877034957 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/385 122/18639 0.00819672131147541 0.396827762401533 0.922289421307197 0.949902877034957 GO:0001653 peptide receptor activity 1/385 128/18639 0.0078125 0.378226461038961 0.931494857432513 0.956795401706787 GO:0019787 ubiquitin-like protein transferase activity 6/385 479/18639 0.0125260960334029 0.606425724588564 0.933294543579446 0.956795401706787 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/385 130/18639 0.00769230769230769 0.372407592407592 0.934314899940841 0.956795401706787 GO:0005262 calcium channel activity 1/385 131/18639 0.00763358778625954 0.369564786358679 0.935681195446961 0.956795401706787 GO:0061630 ubiquitin protein ligase activity 4/385 353/18639 0.0113314447592068 0.548589087965858 0.935935036843994 0.956795401706787 GO:0015291 secondary active transmembrane transporter activity 3/385 287/18639 0.0104529616724739 0.506059097696728 0.938042220612399 0.957526777123635 GO:0044325 transmembrane transporter binding 1/385 136/18639 0.00735294117647059 0.355977845683728 0.9420990117498 0.959694937467698 GO:0070851 growth factor receptor binding 1/385 139/18639 0.00719424460431655 0.348294870597029 0.945638829497896 0.959694937467698 GO:0140767 enzyme-substrate adaptor activity 1/385 139/18639 0.00719424460431655 0.348294870597029 0.945638829497896 0.959694937467698 GO:0016755 aminoacyltransferase activity 6/385 496/18639 0.0120967741935484 0.585640971931294 0.945745883144039 0.959694937467698 GO:0000287 magnesium ion binding 2/385 230/18639 0.00869565217391304 0.420982495765104 0.952806681268914 0.964294172143431 GO:0015293 symporter activity 1/385 146/18639 0.00684931506849315 0.331595801458815 0.95308144921153 0.964294172143431 GO:0005216 monoatomic ion channel activity 5/385 448/18639 0.0111607142857143 0.540323515769944 0.956411085102979 0.965408093906229 GO:0004842 ubiquitin-protein transferase activity 5/385 449/18639 0.0111358574610245 0.539120122639054 0.956988837273326 0.965408093906229 GO:0140375 immune receptor activity 1/385 156/18639 0.00641025641025641 0.31033966033966 0.961985150605239 0.96902750163456 GO:0015276 ligand-gated monoatomic ion channel activity 1/385 186/18639 0.00537634408602151 0.260284876413909 0.979794052735996 0.984923148852996 GO:0022834 ligand-gated channel activity 1/385 188/18639 0.00531914893617021 0.257515888366952 0.980628425820207 0.984923148852996 GO:0005261 monoatomic cation channel activity 2/385 341/18639 0.00586510263929619 0.283947137906082 0.993680048608018 0.996577074988799 GO:0022836 gated channel activity 1/385 318/18639 0.00314465408805031 0.152242097525116 0.998762880754327 0.999448484980753 GO:0045182 translation regulator activity 1/385 356/18639 0.00280898876404494 0.135991536553334 0.999448484980753 0.999448484980753