ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0140375 immune receptor activity 16/299 156/18639 0.102564102564103 6.39361975816825 4.54345938587189e-09 2.76242330661011e-06 GO:0005201 extracellular matrix structural constituent 16/299 168/18639 0.0952380952380952 5.93693263258481 1.32690669492548e-08 4.03379635257345e-06 GO:0023023 MHC protein complex binding 8/299 37/18639 0.216216216216216 13.4784416523547 1.02931434504794e-07 2.08607707263049e-05 GO:0005520 insulin-like growth factor binding 6/299 19/18639 0.315789473684211 19.685618729097 3.68890847694571e-07 5.60714088495749e-05 GO:0048306 calcium-dependent protein binding 10/299 80/18639 0.125 7.79222408026756 5.93441149036505e-07 7.2162443722839e-05 GO:0050840 extracellular matrix binding 9/299 67/18639 0.134328358208955 8.37373333998902 1.18017324353052e-06 0.00011959088867776 GO:0023026 MHC class II protein complex binding 6/299 27/18639 0.222222222222222 13.8528428093645 3.61215550834439e-06 0.000313741507010484 GO:0001968 fibronectin binding 6/299 30/18639 0.2 12.4675585284281 6.95822038243156e-06 0.000528824749064798 GO:0019838 growth factor binding 11/299 136/18639 0.0808823529411765 5.04202734605548 1.24069944713779e-05 0.000838161404288642 GO:0050786 RAGE receptor binding 4/299 11/18639 0.363636363636364 22.6682882335056 1.95979344505364e-05 0.00108464737713917 GO:0005518 collagen binding 8/299 72/18639 0.111111111111111 6.92642140468227 1.962355452061e-05 0.00108464737713917 GO:0004896 cytokine receptor activity 9/299 96/18639 0.09375 5.84416806020067 2.38458575384216e-05 0.00116086044561656 GO:0003735 structural constituent of ribosome 12/299 175/18639 0.0685714285714286 4.27459149546106 2.66565131899476e-05 0.00116086044561656 GO:0005125 cytokine activity 14/299 234/18639 0.0598290598290598 3.72961152559815 2.67303392082761e-05 0.00116086044561656 GO:0031994 insulin-like growth factor I binding 4/299 13/18639 0.307692307692308 19.1808592745048 4.13974330713814e-05 0.00167797595382666 GO:0030246 carbohydrate binding 15/299 280/18639 0.0535714285714286 3.33952460582895 4.98508230980253e-05 0.00188683780214041 GO:0042277 peptide binding 14/299 249/18639 0.0562248995983936 3.50493613248983 5.27569780203732e-05 0.00188683780214041 GO:0042605 peptide antigen binding 6/299 45/18639 0.133333333333333 8.31170568561873 7.79937283751849e-05 0.00263445482511736 GO:0008142 oxysterol binding 4/299 16/18639 0.25 15.5844481605351 0.00010144164746293 0.00324613271881376 GO:0005539 glycosaminoglycan binding 13/299 242/18639 0.0537190082644628 3.34872439813151 0.000153368649363199 0.00466240694064126 GO:0002020 protease binding 9/299 136/18639 0.0661764705882353 4.12529510131812 0.000352530953163736 0.0102066104535025 GO:0032395 MHC class II receptor activity 3/299 10/18639 0.3 18.7013377926421 0.000451106806171725 0.0124669517342004 GO:0005126 cytokine receptor binding 13/299 275/18639 0.0472727272727273 2.94687747035573 0.000526378981617077 0.0130697281281299 GO:0019955 cytokine binding 9/299 144/18639 0.0625 3.89611204013378 0.000535817080533175 0.0130697281281299 GO:0035198 miRNA binding 5/299 42/18639 0.119047619047619 7.42116579073101 0.000537406584215867 0.0130697281281299 GO:0008009 chemokine activity 5/299 45/18639 0.111111111111111 6.92642140468227 0.000742196871335207 0.0173559883758387 GO:0035325 Toll-like receptor binding 3/299 13/18639 0.230769230769231 14.3856444558786 0.0010374021114603 0.0226327753306684 GO:0042379 chemokine receptor binding 6/299 72/18639 0.0833333333333333 5.19481605351171 0.00104229886391236 0.0226327753306684 GO:0043236 laminin binding 4/299 29/18639 0.137931034482759 8.59831622650213 0.00112337961131871 0.0235522346097165 GO:0005178 integrin binding 9/299 161/18639 0.0559006211180124 3.48472132782152 0.00118784929998688 0.0240737458130674 GO:0005041 low-density lipoprotein particle receptor activity 3/299 15/18639 0.2 12.4675585284281 0.00161164076186888 0.0316089542972992 GO:0030296 protein tyrosine kinase activator activity 4/299 33/18639 0.121212121212121 7.55609607783521 0.0018405215068498 0.0349699086301463 GO:0003823 antigen binding 9/299 174/18639 0.0517241379310345 3.2243685849383 0.00203101713238563 0.0374199520148625 GO:0061980 regulatory RNA binding 5/299 58/18639 0.0862068965517241 5.37394764156383 0.00235030078270897 0.0397245565915294 GO:0030169 low-density lipoprotein particle binding 3/299 17/18639 0.176470588235294 11.0007869368483 0.00235211190344582 0.0397245565915294 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 3/299 17/18639 0.176470588235294 11.0007869368483 0.00235211190344582 0.0397245565915294 GO:0030228 lipoprotein particle receptor activity 3/299 18/18639 0.166666666666667 10.3896321070234 0.00278927633469706 0.0452036527420386 GO:0030280 structural constituent of skin epidermis 4/299 37/18639 0.108108108108108 6.73922082617735 0.00282522829637742 0.0452036527420386 GO:0004857 enzyme inhibitor activity 15/299 416/18639 0.0360576923076923 2.24775694623103 0.00308305934661477 0.0480641046856867 GO:0034987 immunoglobulin receptor binding 3/299 19/18639 0.157894736842105 9.8428093645485 0.00327326849290629 0.0497536810921757 GO:0051879 Hsp90 protein binding 4/299 42/18639 0.0952380952380952 5.93693263258481 0.00449767941585764 0.0666972947522304 GO:0032934 sterol binding 5/299 68/18639 0.0735294117647059 4.5836612236868 0.00469720174943351 0.0679975872298947 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/299 22/18639 0.136363636363636 8.50060808756461 0.00502080119259962 0.07099179360699 GO:0097110 scaffold protein binding 5/299 70/18639 0.0714285714285714 4.4526994744386 0.00531458698844638 0.0718834377686925 GO:0030020 extracellular matrix structural constituent conferring tensile strength 4/299 44/18639 0.0909090909090909 5.66707205837641 0.00532032022959073 0.0718834377686925 GO:0005212 structural constituent of eye lens 3/299 23/18639 0.130434782608696 8.13101643158354 0.00570616164273712 0.0754205712779168 GO:0005540 hyaluronic acid binding 3/299 24/18639 0.125 7.79222408026756 0.00644485922819852 0.0816348835571813 GO:0019957 C-C chemokine binding 3/299 24/18639 0.125 7.79222408026756 0.00644485922819852 0.0816348835571813 GO:0008201 heparin binding 8/299 172/18639 0.0465116279069767 2.89943221591351 0.00668941935624816 0.0818823335481548 GO:0005504 fatty acid binding 4/299 47/18639 0.0851063829787234 5.30534405465025 0.0067337445352101 0.0818823335481548 GO:0005496 steroid binding 6/299 108/18639 0.0555555555555556 3.46321070234114 0.00792051699918424 0.094424986970667 GO:0001664 G protein-coupled receptor binding 11/299 297/18639 0.037037037037037 2.30880713489409 0.00875308184706216 0.102343726211804 GO:0005200 structural constituent of cytoskeleton 6/299 112/18639 0.0535714285714286 3.33952460582895 0.0093943421153114 0.107769056719044 GO:0061135 endopeptidase regulator activity 8/299 184/18639 0.0434782608695652 2.71033881052785 0.00985613402607305 0.110972768293563 GO:0005381 iron ion transmembrane transporter activity 2/299 10/18639 0.2 12.4675585284281 0.0106008274769975 0.113132606413923 GO:0001540 amyloid-beta binding 5/299 83/18639 0.0602409638554217 3.75528871338196 0.0107837588674207 0.113132606413923 GO:0140463 chromatin-protein adaptor activity 4/299 54/18639 0.0740740740740741 4.61761426978818 0.0109440194494851 0.113132606413923 GO:0051861 glycolipid binding 3/299 29/18639 0.103448275862069 6.4487371698766 0.0109703932956942 0.113132606413923 GO:0061134 peptidase regulator activity 9/299 226/18639 0.0398230088495575 2.48247846804984 0.01097832858293 0.113132606413923 GO:0140313 molecular sequestering activity 4/299 55/18639 0.0727272727272727 4.53365764670112 0.011656863503003 0.118122883497097 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/299 30/18639 0.1 6.23377926421405 0.0120471035984923 0.120076048981694 GO:0048407 platelet-derived growth factor binding 2/299 11/18639 0.181818181818182 11.3341441167528 0.0128203618867598 0.123726667097618 GO:0050998 nitric-oxide synthase binding 2/299 11/18639 0.181818181818182 11.3341441167528 0.0128203618867598 0.123726667097618 GO:0051082 unfolded protein binding 6/299 121/18639 0.0495867768595041 3.09113021365986 0.0134081919350198 0.127377823382688 GO:0071813 lipoprotein particle binding 3/299 32/18639 0.09375 5.84416806020067 0.0143766304733831 0.132439262542681 GO:0071814 protein-lipid complex binding 3/299 32/18639 0.09375 5.84416806020067 0.0143766304733831 0.132439262542681 GO:0001786 phosphatidylserine binding 4/299 59/18639 0.0677966101694915 4.22629102658579 0.0148036997129985 0.134338051126912 GO:0005095 GTPase inhibitor activity 2/299 12/18639 0.166666666666667 10.3896321070234 0.0152229232885146 0.135086584817635 GO:0004866 endopeptidase inhibitor activity 7/299 161/18639 0.0434782608695652 2.71033881052785 0.0153305499217382 0.135086584817635 GO:0019956 chemokine binding 3/299 33/18639 0.0909090909090909 5.66707205837641 0.0156302413700364 0.135759810756888 GO:0031072 heat shock protein binding 6/299 131/18639 0.0458015267175573 2.85516607521254 0.0191265373704902 0.163787812975466 GO:0030414 peptidase inhibitor activity 7/299 169/18639 0.0414201183431953 2.58203874849103 0.0194749431197414 0.164455075233372 GO:0005161 platelet-derived growth factor receptor binding 2/299 14/18639 0.142857142857143 8.90539894887721 0.0205516732916307 0.168856991369074 GO:0044548 S100 protein binding 2/299 14/18639 0.142857142857143 8.90539894887721 0.0205516732916307 0.168856991369074 GO:0043394 proteoglycan binding 3/299 37/18639 0.0810810810810811 5.05441561963301 0.0212431722538567 0.172211316404598 GO:0005501 retinoid binding 3/299 38/18639 0.0789473684210526 4.92140468227425 0.0227967327715535 0.180005370455903 GO:0019840 isoprenoid binding 3/299 38/18639 0.0789473684210526 4.92140468227425 0.0227967327715535 0.180005370455903 GO:0004674 protein serine/threonine kinase activity 13/299 433/18639 0.0300230946882217 1.87157345114971 0.0231300201241707 0.180295541480715 GO:0005523 tropomyosin binding 2/299 15/18639 0.133333333333333 8.31170568561873 0.0234655244500556 0.180595428678909 GO:0030295 protein kinase activator activity 6/299 139/18639 0.0431654676258993 2.69083997016434 0.0247561473150532 0.185823920587066 GO:0070851 growth factor receptor binding 6/299 139/18639 0.0431654676258993 2.69083997016434 0.0247561473150532 0.185823920587066 GO:0004708 MAP kinase kinase activity 2/299 16/18639 0.125 7.79222408026756 0.0265377210500909 0.194396799981389 GO:0019841 retinol binding 2/299 16/18639 0.125 7.79222408026756 0.0265377210500909 0.194396799981389 GO:0042056 chemoattractant activity 3/299 42/18639 0.0714285714285714 4.4526994744386 0.0296123410113904 0.205631603559962 GO:0036041 long-chain fatty acid binding 2/299 17/18639 0.117647058823529 7.33385795789888 0.0297624689363102 0.205631603559962 GO:0045236 CXCR chemokine receptor binding 2/299 17/18639 0.117647058823529 7.33385795789888 0.0297624689363102 0.205631603559962 GO:0051787 misfolded protein binding 2/299 17/18639 0.117647058823529 7.33385795789888 0.0297624689363102 0.205631603559962 GO:0070492 oligosaccharide binding 2/299 17/18639 0.117647058823529 7.33385795789888 0.0297624689363102 0.205631603559962 GO:0048156 tau protein binding 3/299 43/18639 0.0697674418604651 4.34914832387027 0.0314659602316673 0.214555137419722 GO:0106310 protein serine kinase activity 11/299 361/18639 0.0304709141274238 1.89948952649181 0.0319420829482173 0.214555137419722 GO:0019209 kinase activator activity 6/299 148/18639 0.0405405405405405 2.52720780981651 0.0323018059838591 0.214555137419722 GO:0044183 protein folding chaperone 4/299 75/18639 0.0533333333333333 3.32468227424749 0.0324655800043 0.214555137419722 GO:0098641 cadherin binding involved in cell-cell adhesion 2/299 18/18639 0.111111111111111 6.92642140468227 0.0331341180115119 0.215898573954019 GO:0001223 transcription coactivator binding 3/299 44/18639 0.0681818181818182 4.2503040437823 0.0333790558415754 0.215898573954019 GO:0016918 retinal binding 2/299 19/18639 0.105263157894737 6.561872909699 0.0366471591313479 0.234541818440626 GO:0001221 transcription coregulator binding 5/299 115/18639 0.0434782608695652 2.71033881052785 0.0379063246559006 0.23709577067084 GO:0033293 monocarboxylic acid binding 4/299 79/18639 0.0506329113924051 3.15634393124762 0.0382160946147077 0.23709577067084 GO:0046332 SMAD binding 4/299 79/18639 0.0506329113924051 3.15634393124762 0.0382160946147077 0.23709577067084 GO:0016004 phospholipase activator activity 2/299 20/18639 0.1 6.23377926421405 0.0402962210609824 0.247475781869468 GO:0038187 pattern recognition receptor activity 3/299 48/18639 0.0625 3.89611204013378 0.0416200220079294 0.253049733808211 GO:0072542 protein phosphatase activator activity 2/299 21/18639 0.0952380952380952 5.93693263258481 0.0440760674925995 0.265329198371292 GO:0048020 CCR chemokine receptor binding 3/299 50/18639 0.06 3.74026755852843 0.0460882930069036 0.274722374001935 GO:0008083 growth factor activity 6/299 162/18639 0.037037037037037 2.30880713489409 0.0467603556045617 0.276022293277413 GO:0033691 sialic acid binding 2/299 22/18639 0.0909090909090909 5.66707205837641 0.0479815941225995 0.277836278348005 GO:0050321 tau-protein kinase activity 2/299 22/18639 0.0909090909090909 5.66707205837641 0.0479815941225995 0.277836278348005 GO:0016209 antioxidant activity 4/299 86/18639 0.0465116279069767 2.89943221591351 0.0495942759646649 0.28446528100487 GO:0004602 glutathione peroxidase activity 2/299 23/18639 0.0869565217391304 5.42067762105569 0.0520078257873483 0.290098697969796 GO:0016493 C-C chemokine receptor activity 2/299 23/18639 0.0869565217391304 5.42067762105569 0.0520078257873483 0.290098697969796 GO:0043274 phospholipase binding 2/299 23/18639 0.0869565217391304 5.42067762105569 0.0520078257873483 0.290098697969796 GO:0003779 actin binding 12/299 443/18639 0.0270880361173815 1.68860837856814 0.0545867776664731 0.301716007465597 GO:0050431 transforming growth factor beta binding 2/299 24/18639 0.0833333333333333 5.19481605351171 0.0561499136563619 0.304813816991679 GO:0060229 lipase activator activity 2/299 24/18639 0.0833333333333333 5.19481605351171 0.0561499136563619 0.304813816991679 GO:0072341 modified amino acid binding 4/299 91/18639 0.043956043956044 2.74012275350068 0.0587413362779459 0.310762959091436 GO:0141003 histone H2AX kinase activity 10/299 354/18639 0.0282485875706215 1.76095459441075 0.060206179412712 0.310762959091436 GO:0004709 MAP kinase kinase kinase activity 2/299 25/18639 0.08 4.98702341137124 0.0604031324818304 0.310762959091436 GO:0019211 phosphatase activator activity 2/299 25/18639 0.08 4.98702341137124 0.0604031324818304 0.310762959091436 GO:0170055 lipid transmembrane transporter activity 3/299 56/18639 0.0535714285714286 3.33952460582895 0.0608374332010353 0.310762959091436 GO:0140996 histone H3 kinase activity 10/299 357/18639 0.0280112044817927 1.74615665664259 0.0629659454964554 0.310762959091436 GO:0004252 serine-type endopeptidase activity 6/299 176/18639 0.0340909090909091 2.12515202189115 0.0646868010355233 0.310762959091436 GO:0001637 G protein-coupled chemoattractant receptor activity 2/299 26/18639 0.0769230769230769 4.79521481862619 0.0647628779034052 0.310762959091436 GO:0004950 chemokine receptor activity 2/299 26/18639 0.0769230769230769 4.79521481862619 0.0647628779034052 0.310762959091436 GO:0008198 ferrous iron binding 2/299 26/18639 0.0769230769230769 4.79521481862619 0.0647628779034052 0.310762959091436 GO:0019865 immunoglobulin binding 2/299 26/18639 0.0769230769230769 4.79521481862619 0.0647628779034052 0.310762959091436 GO:0030247 polysaccharide binding 2/299 26/18639 0.0769230769230769 4.79521481862619 0.0647628779034052 0.310762959091436 GO:0050750 low-density lipoprotein particle receptor binding 2/299 26/18639 0.0769230769230769 4.79521481862619 0.0647628779034052 0.310762959091436 GO:0070412 R-SMAD binding 2/299 26/18639 0.0769230769230769 4.79521481862619 0.0647628779034052 0.310762959091436 GO:0051087 protein-folding chaperone binding 5/299 134/18639 0.0373134328358209 2.32603703888584 0.0649126575733757 0.310762959091436 GO:0035173 histone kinase activity 10/299 360/18639 0.0277777777777778 1.73160535117057 0.0658063393307263 0.31258011182095 GO:0044325 transmembrane transporter binding 5/299 136/18639 0.0367647058823529 2.2918306118434 0.068251038589312 0.321679313661254 GO:0004879 nuclear receptor activity 3/299 59/18639 0.0508474576271186 3.16971826993935 0.068938989146916 0.322422349240961 GO:0098531 ligand-modulated transcription factor activity 3/299 60/18639 0.05 3.11688963210702 0.0717428235812533 0.33297432623971 GO:0046875 ephrin receptor binding 2/299 28/18639 0.0714285714285714 4.4526994744386 0.0737841197379281 0.334781677616868 GO:0097718 disordered domain specific binding 2/299 28/18639 0.0714285714285714 4.4526994744386 0.0737841197379281 0.334781677616868 GO:0141052 histone H3 demethylase activity 2/299 28/18639 0.0714285714285714 4.4526994744386 0.0737841197379281 0.334781677616868 GO:1901681 sulfur compound binding 8/299 275/18639 0.0290909090909091 1.81346305868045 0.0763315270783474 0.343774581212113 GO:0004629 phospholipase C activity 2/299 29/18639 0.0689655172413793 4.29915811325107 0.0784369883632788 0.350659477388776 GO:0031406 carboxylic acid binding 6/299 187/18639 0.0320855614973262 2.00014307942697 0.0812459286063719 0.360565872939227 GO:0032452 histone demethylase activity 2/299 30/18639 0.0666666666666667 4.15585284280936 0.083179122989335 0.363833861708746 GO:0048019 receptor antagonist activity 2/299 30/18639 0.0666666666666667 4.15585284280936 0.083179122989335 0.363833861708746 GO:0043177 organic acid binding 6/299 189/18639 0.0317460317460317 1.97897754419494 0.0844892102745599 0.365746472805811 GO:0038024 cargo receptor activity 3/299 65/18639 0.0461538461538462 2.87712889117571 0.0865041623430784 0.365746472805811 GO:0070325 lipoprotein particle receptor binding 2/299 31/18639 0.0645161290322581 4.02179307368648 0.0880064851262509 0.365746472805811 GO:0140457 protein demethylase activity 2/299 31/18639 0.0645161290322581 4.02179307368648 0.0880064851262509 0.365746472805811 GO:0045296 cadherin binding 9/299 334/18639 0.0269461077844311 1.67976087957864 0.0903826445424361 0.365746472805811 GO:0019207 kinase regulator activity 8/299 287/18639 0.0278745644599303 1.73763881929311 0.0920832953989639 0.365746472805811 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3/299 67/18639 0.0447761194029851 2.79124444666301 0.0927407338101811 0.365746472805811 GO:0008236 serine-type peptidase activity 6/299 194/18639 0.0309278350515464 1.92797296831362 0.092906458195145 0.365746472805811 GO:0019888 protein phosphatase regulator activity 4/299 107/18639 0.0373831775700935 2.3303847716688 0.0935226219558651 0.365746472805811 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 7/299 243/18639 0.0288065843621399 1.7957388826954 0.0972798749430334 0.365746472805811 GO:0017171 serine hydrolase activity 6/299 198/18639 0.0303030303030303 1.8890240194588 0.0999545064387784 0.365746472805811 GO:0004676 3-phosphoinositide-dependent protein kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0004711 ribosomal protein S6 kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0035175 histone H3S10 kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0035979 histone H2AXS139 kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0044022 histone H3S28 kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0044023 histone H4S1 kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0044024 histone H2AS1 kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0044025 histone H2BS14 kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0072354 histone H3T3 kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0072371 histone H2AS121 kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0072518 Rho-dependent protein serine/threonine kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0140823 histone H2BS36 kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0140855 histone H3S57 kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0140995 histone H2A kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0140997 histone H4 kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0140998 histone H2B kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:1990244 histone H2AT120 kinase activity 7/299 245/18639 0.0285714285714286 1.78107978977544 0.100459968681859 0.365746472805811 GO:0004677 DNA-dependent protein kinase activity 7/299 246/18639 0.0284552845528455 1.77383962802839 0.102071192991248 0.366554996485411 GO:0140857 histone H3T45 kinase activity 7/299 246/18639 0.0284552845528455 1.77383962802839 0.102071192991248 0.366554996485411 GO:0033218 amide binding 7/299 247/18639 0.0283400809716599 1.76665809107281 0.103696479268899 0.366554996485411 GO:0035402 histone H3T11 kinase activity 7/299 247/18639 0.0283400809716599 1.76665809107281 0.103696479268899 0.366554996485411 GO:0035403 histone H3T6 kinase activity 7/299 247/18639 0.0283400809716599 1.76665809107281 0.103696479268899 0.366554996485411 GO:0004679 AMP-activated protein kinase activity 7/299 248/18639 0.0282258064516129 1.75953446973784 0.105335782881307 0.370197433478814 GO:0005154 epidermal growth factor receptor binding 2/299 35/18639 0.0571428571428571 3.56215957955088 0.108091093904296 0.377697615481679 GO:0004521 RNA endonuclease activity 3/299 73/18639 0.0410958904109589 2.56182709488249 0.112505104276733 0.388908537364652 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/299 36/18639 0.0555555555555556 3.46321070234114 0.113287639107697 0.388908537364652 GO:0035401 histone H3Y41 kinase activity 4/299 115/18639 0.0347826086956522 2.16827104842228 0.113858091531099 0.388908537364652 GO:0140801 histone H2AXY142 kinase activity 4/299 115/18639 0.0347826086956522 2.16827104842228 0.113858091531099 0.388908537364652 GO:0099106 ion channel regulator activity 5/299 160/18639 0.03125 1.94805602006689 0.115420878384117 0.392044100880131 GO:0019887 protein kinase regulator activity 7/299 255/18639 0.0274509803921569 1.71123352350974 0.117199250878387 0.395873025189219 GO:0030551 cyclic nucleotide binding 2/299 37/18639 0.0540540540540541 3.36961041308867 0.118547322927916 0.39821421182416 GO:0019208 phosphatase regulator activity 4/299 117/18639 0.0341880341880342 2.13120658605608 0.119224047792293 0.39828692888854 GO:0017022 myosin binding 3/299 76/18639 0.0394736842105263 2.46070234113712 0.122939073230389 0.408453314339215 GO:0043531 ADP binding 2/299 38/18639 0.0526315789473684 3.2809364548495 0.123866800158825 0.409298991829161 GO:0004540 RNA nuclease activity 4/299 121/18639 0.0330578512396694 2.06075347577324 0.130275754145647 0.428149505516505 GO:0016247 channel regulator activity 5/299 168/18639 0.0297619047619048 1.85529144768275 0.133884100908459 0.432408211719801 GO:0004532 RNA exonuclease activity 2/299 40/18639 0.05 3.11688963210702 0.134672204123031 0.432408211719801 GO:0032451 demethylase activity 2/299 40/18639 0.05 3.11688963210702 0.134672204123031 0.432408211719801 GO:0141108 transporter regulator activity 5/299 170/18639 0.0294117647058824 1.83346448947472 0.13869584608465 0.432408211719801 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/299 41/18639 0.0487804878048781 3.04086793376295 0.140151884508227 0.432408211719801 GO:0042287 MHC protein binding 2/299 41/18639 0.0487804878048781 3.04086793376295 0.140151884508227 0.432408211719801 GO:0001618 virus receptor activity 3/299 81/18639 0.037037037037037 2.30880713489409 0.141066510924463 0.432408211719801 GO:0015101 organic cation transmembrane transporter activity 3/299 81/18639 0.037037037037037 2.30880713489409 0.141066510924463 0.432408211719801 GO:0140272 exogenous protein binding 3/299 82/18639 0.0365853658536585 2.28065095032221 0.144794826076949 0.432408211719801 GO:0008307 structural constituent of muscle 2/299 42/18639 0.0476190476190476 2.9684663162924 0.145678861683069 0.432408211719801 GO:0019894 kinesin binding 2/299 42/18639 0.0476190476190476 2.9684663162924 0.145678861683069 0.432408211719801 GO:0001094 TFIID-class transcription factor complex binding 1/299 10/18639 0.1 6.23377926421405 0.149351520495326 0.432408211719801 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/299 10/18639 0.1 6.23377926421405 0.149351520495326 0.432408211719801 GO:0003796 lysozyme activity 1/299 10/18639 0.1 6.23377926421405 0.149351520495326 0.432408211719801 GO:0005031 tumor necrosis factor receptor activity 1/299 10/18639 0.1 6.23377926421405 0.149351520495326 0.432408211719801 GO:0005345 purine nucleobase transmembrane transporter activity 1/299 10/18639 0.1 6.23377926421405 0.149351520495326 0.432408211719801 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/299 10/18639 0.1 6.23377926421405 0.149351520495326 0.432408211719801 GO:0015187 glycine transmembrane transporter activity 1/299 10/18639 0.1 6.23377926421405 0.149351520495326 0.432408211719801 GO:0015203 polyamine transmembrane transporter activity 1/299 10/18639 0.1 6.23377926421405 0.149351520495326 0.432408211719801 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/299 10/18639 0.1 6.23377926421405 0.149351520495326 0.432408211719801 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/299 10/18639 0.1 6.23377926421405 0.149351520495326 0.432408211719801 GO:0030957 Tat protein binding 1/299 10/18639 0.1 6.23377926421405 0.149351520495326 0.432408211719801 GO:0031434 mitogen-activated protein kinase kinase binding 1/299 10/18639 0.1 6.23377926421405 0.149351520495326 0.432408211719801 GO:0035256 G protein-coupled glutamate receptor binding 1/299 10/18639 0.1 6.23377926421405 0.149351520495326 0.432408211719801 GO:0043208 glycosphingolipid binding 1/299 10/18639 0.1 6.23377926421405 0.149351520495326 0.432408211719801 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/299 43/18639 0.0465116279069767 2.89943221591351 0.151250222729479 0.432780868578859 GO:0043021 ribonucleoprotein complex binding 5/299 177/18639 0.0282485875706215 1.76095459441075 0.156119223493146 0.432780868578859 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4/299 130/18639 0.0307692307692308 1.91808592745048 0.156595275817331 0.432780868578859 GO:0030547 signaling receptor inhibitor activity 2/299 44/18639 0.0454545454545455 2.8335360291882 0.156863135438426 0.432780868578859 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/299 45/18639 0.0444444444444444 2.77056856187291 0.16251484648469 0.432780868578859 GO:0046915 transition metal ion transmembrane transporter activity 2/299 45/18639 0.0444444444444444 2.77056856187291 0.16251484648469 0.432780868578859 GO:0008199 ferric iron binding 1/299 11/18639 0.0909090909090909 5.66707205837641 0.163004636356182 0.432780868578859 GO:0008432 JUN kinase binding 1/299 11/18639 0.0909090909090909 5.66707205837641 0.163004636356182 0.432780868578859 GO:0015173 aromatic amino acid transmembrane transporter activity 1/299 11/18639 0.0909090909090909 5.66707205837641 0.163004636356182 0.432780868578859 GO:0015205 nucleobase transmembrane transporter activity 1/299 11/18639 0.0909090909090909 5.66707205837641 0.163004636356182 0.432780868578859 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/299 11/18639 0.0909090909090909 5.66707205837641 0.163004636356182 0.432780868578859 GO:0019215 intermediate filament binding 1/299 11/18639 0.0909090909090909 5.66707205837641 0.163004636356182 0.432780868578859 GO:0019864 IgG binding 1/299 11/18639 0.0909090909090909 5.66707205837641 0.163004636356182 0.432780868578859 GO:0032050 clathrin heavy chain binding 1/299 11/18639 0.0909090909090909 5.66707205837641 0.163004636356182 0.432780868578859 GO:0034511 U3 snoRNA binding 1/299 11/18639 0.0909090909090909 5.66707205837641 0.163004636356182 0.432780868578859 GO:0042608 T cell receptor binding 1/299 11/18639 0.0909090909090909 5.66707205837641 0.163004636356182 0.432780868578859 GO:0097493 structural molecule activity conferring elasticity 1/299 11/18639 0.0909090909090909 5.66707205837641 0.163004636356182 0.432780868578859 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/299 11/18639 0.0909090909090909 5.66707205837641 0.163004636356182 0.432780868578859 GO:1990948 ubiquitin ligase inhibitor activity 1/299 11/18639 0.0909090909090909 5.66707205837641 0.163004636356182 0.432780868578859 GO:0008081 phosphoric diester hydrolase activity 3/299 87/18639 0.0344827586206897 2.14957905662553 0.163902866923298 0.433273665605936 GO:0031267 small GTPase binding 7/299 283/18639 0.0247349823321555 1.54192419962892 0.171064720811196 0.441461387764792 GO:0001784 phosphotyrosine residue binding 2/299 47/18639 0.0425531914893617 2.65267202732513 0.173924034017464 0.441461387764792 GO:0000340 RNA 7-methylguanosine cap binding 1/299 12/18639 0.0833333333333333 5.19481605351171 0.176439337544152 0.441461387764792 GO:0004126 cytidine deaminase activity 1/299 12/18639 0.0833333333333333 5.19481605351171 0.176439337544152 0.441461387764792 GO:0004859 phospholipase inhibitor activity 1/299 12/18639 0.0833333333333333 5.19481605351171 0.176439337544152 0.441461387764792 GO:0005078 MAP-kinase scaffold activity 1/299 12/18639 0.0833333333333333 5.19481605351171 0.176439337544152 0.441461387764792 GO:0015132 prostaglandin transmembrane transporter activity 1/299 12/18639 0.0833333333333333 5.19481605351171 0.176439337544152 0.441461387764792 GO:0015166 polyol transmembrane transporter activity 1/299 12/18639 0.0833333333333333 5.19481605351171 0.176439337544152 0.441461387764792 GO:0035197 siRNA binding 1/299 12/18639 0.0833333333333333 5.19481605351171 0.176439337544152 0.441461387764792 GO:0035497 cAMP response element binding 1/299 12/18639 0.0833333333333333 5.19481605351171 0.176439337544152 0.441461387764792 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/299 12/18639 0.0833333333333333 5.19481605351171 0.176439337544152 0.441461387764792 GO:0097371 MDM2/MDM4 family protein binding 1/299 12/18639 0.0833333333333333 5.19481605351171 0.176439337544152 0.441461387764792 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/299 12/18639 0.0833333333333333 5.19481605351171 0.176439337544152 0.441461387764792 GO:0043178 alcohol binding 3/299 92/18639 0.0326086956521739 2.03275410789588 0.183709520951253 0.453987152789725 GO:0001222 transcription corepressor binding 2/299 49/18639 0.0408163265306122 2.5443996996792 0.185457269380092 0.453987152789725 GO:0016763 pentosyltransferase activity 2/299 49/18639 0.0408163265306122 2.5443996996792 0.185457269380092 0.453987152789725 GO:0051213 dioxygenase activity 3/299 93/18639 0.032258064516129 2.01089653684324 0.187745330219231 0.453987152789725 GO:0004713 protein tyrosine kinase activity 4/299 140/18639 0.0285714285714286 1.78107978977544 0.187920058110389 0.453987152789725 GO:0005035 death receptor activity 1/299 13/18639 0.0769230769230769 4.79521481862619 0.189659106593076 0.453987152789725 GO:0005172 vascular endothelial growth factor receptor binding 1/299 13/18639 0.0769230769230769 4.79521481862619 0.189659106593076 0.453987152789725 GO:0008035 high-density lipoprotein particle binding 1/299 13/18639 0.0769230769230769 4.79521481862619 0.189659106593076 0.453987152789725 GO:0032396 inhibitory MHC class I receptor activity 1/299 13/18639 0.0769230769230769 4.79521481862619 0.189659106593076 0.453987152789725 GO:0039706 co-receptor binding 1/299 13/18639 0.0769230769230769 4.79521481862619 0.189659106593076 0.453987152789725 GO:0071714 icosanoid transmembrane transporter activity 1/299 13/18639 0.0769230769230769 4.79521481862619 0.189659106593076 0.453987152789725 GO:0032813 tumor necrosis factor receptor superfamily binding 2/299 50/18639 0.04 2.49351170568562 0.191264310062308 0.456034119677973 GO:0003743 translation initiation factor activity 2/299 51/18639 0.0392156862745098 2.44461931929963 0.197095188108415 0.458073462384602 GO:0030544 Hsp70 protein binding 2/299 51/18639 0.0392156862745098 2.44461931929963 0.197095188108415 0.458073462384602 GO:0004065 arylsulfatase activity 1/299 14/18639 0.0714285714285714 4.4526994744386 0.202667370693187 0.458073462384602 GO:0008191 metalloendopeptidase inhibitor activity 1/299 14/18639 0.0714285714285714 4.4526994744386 0.202667370693187 0.458073462384602 GO:0008195 phosphatidate phosphatase activity 1/299 14/18639 0.0714285714285714 4.4526994744386 0.202667370693187 0.458073462384602 GO:0019763 immunoglobulin receptor activity 1/299 14/18639 0.0714285714285714 4.4526994744386 0.202667370693187 0.458073462384602 GO:0019992 diacylglycerol binding 1/299 14/18639 0.0714285714285714 4.4526994744386 0.202667370693187 0.458073462384602 GO:0032036 myosin heavy chain binding 1/299 14/18639 0.0714285714285714 4.4526994744386 0.202667370693187 0.458073462384602 GO:0032454 histone H3K9 demethylase activity 1/299 14/18639 0.0714285714285714 4.4526994744386 0.202667370693187 0.458073462384602 GO:0034236 protein kinase A catalytic subunit binding 1/299 14/18639 0.0714285714285714 4.4526994744386 0.202667370693187 0.458073462384602 GO:0042043 neurexin family protein binding 1/299 14/18639 0.0714285714285714 4.4526994744386 0.202667370693187 0.458073462384602 GO:0043176 amine binding 1/299 14/18639 0.0714285714285714 4.4526994744386 0.202667370693187 0.458073462384602 GO:0061783 peptidoglycan muralytic activity 1/299 14/18639 0.0714285714285714 4.4526994744386 0.202667370693187 0.458073462384602 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/299 14/18639 0.0714285714285714 4.4526994744386 0.202667370693187 0.458073462384602 GO:0004175 endopeptidase activity 9/299 405/18639 0.0222222222222222 1.38528428093645 0.204602362983153 0.460734209976878 GO:0005246 calcium channel regulator activity 2/299 53/18639 0.0377358490566038 2.35236953366568 0.208819525114879 0.465063264724711 GO:0005544 calcium-dependent phospholipid binding 2/299 53/18639 0.0377358490566038 2.35236953366568 0.208819525114879 0.465063264724711 GO:0140296 general transcription initiation factor binding 2/299 53/18639 0.0377358490566038 2.35236953366568 0.208819525114879 0.465063264724711 GO:0015250 water channel activity 1/299 15/18639 0.0666666666666667 4.15585284280936 0.215467502567696 0.471238278996976 GO:0030553 cGMP binding 1/299 15/18639 0.0666666666666667 4.15585284280936 0.215467502567696 0.471238278996976 GO:0051371 muscle alpha-actinin binding 1/299 15/18639 0.0666666666666667 4.15585284280936 0.215467502567696 0.471238278996976 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/299 15/18639 0.0666666666666667 4.15585284280936 0.215467502567696 0.471238278996976 GO:0061578 K63-linked deubiquitinase activity 1/299 15/18639 0.0666666666666667 4.15585284280936 0.215467502567696 0.471238278996976 GO:0043130 ubiquitin binding 3/299 100/18639 0.03 1.87013377926421 0.216590403808614 0.471996292170744 GO:0098632 cell-cell adhesion mediator activity 2/299 55/18639 0.0363636363636364 2.26682882335056 0.220613064714338 0.479045511951135 GO:0005149 interleukin-1 receptor binding 1/299 16/18639 0.0625 3.89611204013378 0.228062821335537 0.483143537881555 GO:0005159 insulin-like growth factor receptor binding 1/299 16/18639 0.0625 3.89611204013378 0.228062821335537 0.483143537881555 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/299 16/18639 0.0625 3.89611204013378 0.228062821335537 0.483143537881555 GO:0008296 3'-5'-DNA exonuclease activity 1/299 16/18639 0.0625 3.89611204013378 0.228062821335537 0.483143537881555 GO:0016722 oxidoreductase activity, acting on metal ions 1/299 16/18639 0.0625 3.89611204013378 0.228062821335537 0.483143537881555 GO:0022858 alanine transmembrane transporter activity 1/299 16/18639 0.0625 3.89611204013378 0.228062821335537 0.483143537881555 GO:0055102 lipase inhibitor activity 1/299 16/18639 0.0625 3.89611204013378 0.228062821335537 0.483143537881555 GO:0004601 peroxidase activity 2/299 57/18639 0.0350877192982456 2.18729096989967 0.232459592700341 0.489049938968191 GO:0016504 peptidase activator activity 2/299 57/18639 0.0350877192982456 2.18729096989967 0.232459592700341 0.489049938968191 GO:0008484 sulfuric ester hydrolase activity 1/299 17/18639 0.0588235294117647 3.66692897894944 0.240456593360488 0.495203536795796 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/299 17/18639 0.0588235294117647 3.66692897894944 0.240456593360488 0.495203536795796 GO:0016018 cyclosporin A binding 1/299 17/18639 0.0588235294117647 3.66692897894944 0.240456593360488 0.495203536795796 GO:0038191 neuropilin binding 1/299 17/18639 0.0588235294117647 3.66692897894944 0.240456593360488 0.495203536795796 GO:0045125 bioactive lipid receptor activity 1/299 17/18639 0.0588235294117647 3.66692897894944 0.240456593360488 0.495203536795796 GO:0008013 beta-catenin binding 3/299 106/18639 0.0283018867924528 1.76427715024926 0.241996711239035 0.495203536795796 GO:0051020 GTPase binding 7/299 315/18639 0.0222222222222222 1.38528428093645 0.243257388211798 0.495203536795796 GO:0015459 potassium channel regulator activity 2/299 59/18639 0.0338983050847458 2.1131455132929 0.244343850392663 0.495203536795796 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/299 59/18639 0.0338983050847458 2.1131455132929 0.244343850392663 0.495203536795796 GO:0045309 protein phosphorylated amino acid binding 2/299 59/18639 0.0338983050847458 2.1131455132929 0.244343850392663 0.495203536795796 GO:0070888 E-box binding 2/299 59/18639 0.0338983050847458 2.1131455132929 0.244343850392663 0.495203536795796 GO:0003730 mRNA 3'-UTR binding 6/299 262/18639 0.0229007633587786 1.42758303760627 0.245319192937215 0.495528469454575 GO:0001098 basal transcription machinery binding 2/299 60/18639 0.0333333333333333 2.07792642140468 0.250295609937884 0.498741675704007 GO:0001099 basal RNA polymerase II transcription machinery binding 2/299 60/18639 0.0333333333333333 2.07792642140468 0.250295609937884 0.498741675704007 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/299 60/18639 0.0333333333333333 2.07792642140468 0.250295609937884 0.498741675704007 GO:0004706 JUN kinase kinase kinase activity 1/299 18/18639 0.0555555555555556 3.46321070234114 0.252652033086898 0.498741675704007 GO:0005372 water transmembrane transporter activity 1/299 18/18639 0.0555555555555556 3.46321070234114 0.252652033086898 0.498741675704007 GO:0016854 racemase and epimerase activity 1/299 18/18639 0.0555555555555556 3.46321070234114 0.252652033086898 0.498741675704007 GO:0032393 MHC class I receptor activity 1/299 18/18639 0.0555555555555556 3.46321070234114 0.252652033086898 0.498741675704007 GO:0015026 coreceptor activity 2/299 61/18639 0.0327868852459016 2.04386205384067 0.256251490579818 0.504210052661908 GO:0015179 L-amino acid transmembrane transporter activity 2/299 62/18639 0.032258064516129 2.01089653684324 0.262209834404887 0.514084986416044 GO:0015245 fatty acid transmembrane transporter activity 1/299 19/18639 0.0526315789473684 3.2809364548495 0.264652303862207 0.514084986416044 GO:0042577 lipid phosphatase activity 1/299 19/18639 0.0526315789473684 3.2809364548495 0.264652303862207 0.514084986416044 GO:0140036 ubiquitin-modified protein reader activity 1/299 19/18639 0.0526315789473684 3.2809364548495 0.264652303862207 0.514084986416044 GO:0000339 RNA cap binding 1/299 20/18639 0.05 3.11688963210702 0.276460518746482 0.533612683802733 GO:0043024 ribosomal small subunit binding 1/299 20/18639 0.05 3.11688963210702 0.276460518746482 0.533612683802733 GO:0019843 rRNA binding 2/299 65/18639 0.0307692307692308 1.91808592745048 0.280083835271379 0.538895480522147 GO:0001846 opsonin binding 1/299 21/18639 0.0476190476190476 2.9684663162924 0.288079741309176 0.547351508487435 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/299 21/18639 0.0476190476190476 2.9684663162924 0.288079741309176 0.547351508487435 GO:0035613 RNA stem-loop binding 1/299 21/18639 0.0476190476190476 2.9684663162924 0.288079741309176 0.547351508487435 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/299 21/18639 0.0476190476190476 2.9684663162924 0.288079741309176 0.547351508487435 GO:1990782 protein tyrosine kinase binding 3/299 117/18639 0.0256410256410256 1.59840493954206 0.289643692083617 0.548608613043113 GO:0061133 endopeptidase activator activity 1/299 22/18639 0.0454545454545455 2.8335360291882 0.299512986413299 0.563789150895621 GO:0140035 ubiquitin-like protein reader activity 1/299 22/18639 0.0454545454545455 2.8335360291882 0.299512986413299 0.563789150895621 GO:0032182 ubiquitin-like protein binding 3/299 120/18639 0.025 1.55844481605351 0.302780019167998 0.568179789055995 GO:0005283 amino acid:sodium symporter activity 1/299 23/18639 0.0434782608695652 2.71033881052785 0.310763220987206 0.57255769200067 GO:0017134 fibroblast growth factor binding 1/299 23/18639 0.0434782608695652 2.71033881052785 0.310763220987206 0.57255769200067 GO:0042171 lysophosphatidic acid acyltransferase activity 1/299 23/18639 0.0434782608695652 2.71033881052785 0.310763220987206 0.57255769200067 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/299 23/18639 0.0434782608695652 2.71033881052785 0.310763220987206 0.57255769200067 GO:0071617 lysophospholipid acyltransferase activity 1/299 23/18639 0.0434782608695652 2.71033881052785 0.310763220987206 0.57255769200067 GO:0099186 structural constituent of postsynapse 1/299 23/18639 0.0434782608695652 2.71033881052785 0.310763220987206 0.57255769200067 GO:0005319 lipid transporter activity 4/299 178/18639 0.0224719101123595 1.40084927285709 0.31996987406206 0.58236513627617 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/299 24/18639 0.0416666666666667 2.59740802675585 0.321833364784199 0.58236513627617 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/299 24/18639 0.0416666666666667 2.59740802675585 0.321833364784199 0.58236513627617 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/299 24/18639 0.0416666666666667 2.59740802675585 0.321833364784199 0.58236513627617 GO:0030552 cAMP binding 1/299 24/18639 0.0416666666666667 2.59740802675585 0.321833364784199 0.58236513627617 GO:0048027 mRNA 5'-UTR binding 1/299 24/18639 0.0416666666666667 2.59740802675585 0.321833364784199 0.58236513627617 GO:0001848 complement binding 1/299 25/18639 0.04 2.49351170568562 0.332726291130131 0.589459510777473 GO:0005251 delayed rectifier potassium channel activity 1/299 25/18639 0.04 2.49351170568562 0.332726291130131 0.589459510777473 GO:0015662 P-type ion transporter activity 1/299 25/18639 0.04 2.49351170568562 0.332726291130131 0.589459510777473 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/299 25/18639 0.04 2.49351170568562 0.332726291130131 0.589459510777473 GO:0017025 TBP-class protein binding 1/299 25/18639 0.04 2.49351170568562 0.332726291130131 0.589459510777473 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/299 25/18639 0.04 2.49351170568562 0.332726291130131 0.589459510777473 GO:0140358 P-type transmembrane transporter activity 1/299 25/18639 0.04 2.49351170568562 0.332726291130131 0.589459510777473 GO:0004519 endonuclease activity 3/299 127/18639 0.0236220472440945 1.47254628288521 0.333509986360939 0.589459510777473 GO:0031490 chromatin DNA binding 3/299 128/18639 0.0234375 1.46104201505017 0.337900252810209 0.589871342420321 GO:0003725 double-stranded RNA binding 2/299 75/18639 0.0266666666666667 1.66234113712375 0.339227198217037 0.589871342420321 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/299 26/18639 0.0384615384615385 2.3976074093131 0.3434448276592 0.589871342420321 GO:0004435 phosphatidylinositol phospholipase C activity 1/299 26/18639 0.0384615384615385 2.3976074093131 0.3434448276592 0.589871342420321 GO:0004529 DNA exonuclease activity 1/299 26/18639 0.0384615384615385 2.3976074093131 0.3434448276592 0.589871342420321 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/299 26/18639 0.0384615384615385 2.3976074093131 0.3434448276592 0.589871342420321 GO:0034237 protein kinase A regulatory subunit binding 1/299 26/18639 0.0384615384615385 2.3976074093131 0.3434448276592 0.589871342420321 GO:0050681 nuclear androgen receptor binding 1/299 26/18639 0.0384615384615385 2.3976074093131 0.3434448276592 0.589871342420321 GO:0051139 metal cation:proton antiporter activity 1/299 26/18639 0.0384615384615385 2.3976074093131 0.3434448276592 0.589871342420321 GO:0070006 metalloaminopeptidase activity 1/299 26/18639 0.0384615384615385 2.3976074093131 0.3434448276592 0.589871342420321 GO:0098631 cell adhesion mediator activity 2/299 76/18639 0.0263157894736842 1.64046822742475 0.345072823216676 0.590997962016167 GO:0001671 ATPase activator activity 1/299 27/18639 0.037037037037037 2.30880713489409 0.353991757038123 0.599518073201055 GO:0004364 glutathione transferase activity 1/299 27/18639 0.037037037037037 2.30880713489409 0.353991757038123 0.599518073201055 GO:0005044 scavenger receptor activity 1/299 27/18639 0.037037037037037 2.30880713489409 0.353991757038123 0.599518073201055 GO:0008266 poly(U) RNA binding 1/299 27/18639 0.037037037037037 2.30880713489409 0.353991757038123 0.599518073201055 GO:0046625 sphingolipid binding 1/299 28/18639 0.0357142857142857 2.2263497372193 0.364369817678871 0.610294350272049 GO:0046966 nuclear thyroid hormone receptor binding 1/299 28/18639 0.0357142857142857 2.2263497372193 0.364369817678871 0.610294350272049 GO:0051019 mitogen-activated protein kinase binding 1/299 28/18639 0.0357142857142857 2.2263497372193 0.364369817678871 0.610294350272049 GO:0051393 alpha-actinin binding 1/299 28/18639 0.0357142857142857 2.2263497372193 0.364369817678871 0.610294350272049 GO:0030971 receptor tyrosine kinase binding 2/299 81/18639 0.0246913580246914 1.53920475659606 0.37402971833132 0.620560425884487 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/299 29/18639 0.0344827586206897 2.14957905662553 0.374581704440142 0.620560425884487 GO:0005416 amino acid:monoatomic cation symporter activity 1/299 29/18639 0.0344827586206897 2.14957905662553 0.374581704440142 0.620560425884487 GO:0097472 cyclin-dependent protein kinase activity 1/299 29/18639 0.0344827586206897 2.14957905662553 0.374581704440142 0.620560425884487 GO:0008187 poly-pyrimidine tract binding 1/299 30/18639 0.0333333333333333 2.07792642140468 0.384630069317756 0.631712591547595 GO:0031624 ubiquitin conjugating enzyme binding 1/299 30/18639 0.0333333333333333 2.07792642140468 0.384630069317756 0.631712591547595 GO:0098918 structural constituent of synapse 1/299 30/18639 0.0333333333333333 2.07792642140468 0.384630069317756 0.631712591547595 GO:0008135 translation factor activity, RNA binding 2/299 83/18639 0.0240963855421687 1.50211548535278 0.385469360960786 0.631712591547595 GO:0004527 exonuclease activity 2/299 84/18639 0.0238095238095238 1.4842331581462 0.391155263816715 0.63759356675754 GO:0180051 translation factor activity 2/299 84/18639 0.0238095238095238 1.4842331581462 0.391155263816715 0.63759356675754 GO:0005164 tumor necrosis factor receptor binding 1/299 31/18639 0.032258064516129 2.01089653684324 0.39451752212414 0.639644409203939 GO:0016411 acylglycerol O-acyltransferase activity 1/299 31/18639 0.032258064516129 2.01089653684324 0.39451752212414 0.639644409203939 GO:0030515 snoRNA binding 1/299 32/18639 0.03125 1.94805602006689 0.404246631157076 0.651941516561014 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/299 32/18639 0.03125 1.94805602006689 0.404246631157076 0.651941516561014 GO:0019239 deaminase activity 1/299 33/18639 0.0303030303030303 1.8890240194588 0.41381992385789 0.658114666843288 GO:0071889 14-3-3 protein binding 1/299 33/18639 0.0303030303030303 1.8890240194588 0.41381992385789 0.658114666843288 GO:0140311 protein sequestering activity 1/299 33/18639 0.0303030303030303 1.8890240194588 0.41381992385789 0.658114666843288 GO:0003727 single-stranded RNA binding 2/299 89/18639 0.0224719101123595 1.40084927285709 0.419217036578311 0.658114666843288 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/299 89/18639 0.0224719101123595 1.40084927285709 0.419217036578311 0.658114666843288 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/299 89/18639 0.0224719101123595 1.40084927285709 0.419217036578311 0.658114666843288 GO:0015631 tubulin binding 7/299 385/18639 0.0181818181818182 1.13341441167528 0.42243870385042 0.658114666843288 GO:0008376 acetylgalactosaminyltransferase activity 1/299 34/18639 0.0294117647058824 1.83346448947472 0.423239887459228 0.658114666843288 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/299 34/18639 0.0294117647058824 1.83346448947472 0.423239887459228 0.658114666843288 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/299 34/18639 0.0294117647058824 1.83346448947472 0.423239887459228 0.658114666843288 GO:0019825 oxygen binding 1/299 34/18639 0.0294117647058824 1.83346448947472 0.423239887459228 0.658114666843288 GO:0030332 cyclin binding 1/299 34/18639 0.0294117647058824 1.83346448947472 0.423239887459228 0.658114666843288 GO:0090482 vitamin transmembrane transporter activity 1/299 34/18639 0.0294117647058824 1.83346448947472 0.423239887459228 0.658114666843288 GO:0019210 kinase inhibitor activity 2/299 90/18639 0.0222222222222222 1.38528428093645 0.424751290759645 0.658114666843288 GO:0140793 histone H2AXY142 phosphatase activity 2/299 90/18639 0.0222222222222222 1.38528428093645 0.424751290759645 0.658114666843288 GO:0004518 nuclease activity 4/299 209/18639 0.0191387559808612 1.19306780176345 0.432319518443528 0.658114666843288 GO:0000175 3'-5'-RNA exonuclease activity 1/299 35/18639 0.0285714285714286 1.78107978977544 0.432508969622608 0.658114666843288 GO:0005343 organic acid:sodium symporter activity 1/299 35/18639 0.0285714285714286 1.78107978977544 0.432508969622608 0.658114666843288 GO:0016229 steroid dehydrogenase activity 1/299 35/18639 0.0285714285714286 1.78107978977544 0.432508969622608 0.658114666843288 GO:0043015 gamma-tubulin binding 1/299 35/18639 0.0285714285714286 1.78107978977544 0.432508969622608 0.658114666843288 GO:0140566 histone reader activity 1/299 35/18639 0.0285714285714286 1.78107978977544 0.432508969622608 0.658114666843288 GO:0052689 carboxylic ester hydrolase activity 2/299 92/18639 0.0217391304347826 1.35516940526392 0.435736977157268 0.658114666843288 GO:0051219 phosphoprotein binding 2/299 93/18639 0.021505376344086 1.34059769122883 0.441187343024039 0.658114666843288 GO:0000993 RNA polymerase II complex binding 1/299 36/18639 0.0277777777777778 1.73160535117057 0.441629579065891 0.658114666843288 GO:0004190 aspartic-type endopeptidase activity 1/299 36/18639 0.0277777777777778 1.73160535117057 0.441629579065891 0.658114666843288 GO:0005484 SNAP receptor activity 1/299 36/18639 0.0277777777777778 1.73160535117057 0.441629579065891 0.658114666843288 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/299 36/18639 0.0277777777777778 1.73160535117057 0.441629579065891 0.658114666843288 GO:0055106 ubiquitin-protein transferase regulator activity 1/299 36/18639 0.0277777777777778 1.73160535117057 0.441629579065891 0.658114666843288 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/299 36/18639 0.0277777777777778 1.73160535117057 0.441629579065891 0.658114666843288 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/299 36/18639 0.0277777777777778 1.73160535117057 0.441629579065891 0.658114666843288 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/299 36/18639 0.0277777777777778 1.73160535117057 0.441629579065891 0.658114666843288 GO:0016410 N-acyltransferase activity 2/299 94/18639 0.0212765957446809 1.32633601366256 0.446608719825874 0.663359042125781 GO:0005506 iron ion binding 3/299 154/18639 0.0194805194805195 1.2143725839378 0.450045338820968 0.663359042125781 GO:0022829 wide pore channel activity 1/299 37/18639 0.027027027027027 1.68480520654434 0.450604086180835 0.663359042125781 GO:0042805 actinin binding 1/299 37/18639 0.027027027027027 1.68480520654434 0.450604086180835 0.663359042125781 GO:0070001 aspartic-type peptidase activity 1/299 37/18639 0.027027027027027 1.68480520654434 0.450604086180835 0.663359042125781 GO:0004867 serine-type endopeptidase inhibitor activity 2/299 95/18639 0.0210526315789474 1.3123745819398 0.452000633528788 0.663807693684791 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/299 38/18639 0.0263157894736842 1.64046822742475 0.459434823640889 0.671481665321299 GO:0042887 amide transmembrane transporter activity 1/299 38/18639 0.0263157894736842 1.64046822742475 0.459434823640889 0.671481665321299 GO:0004725 protein tyrosine phosphatase activity 2/299 98/18639 0.0204081632653061 1.2721998498396 0.467995190290975 0.679282684715097 GO:0000217 DNA secondary structure binding 1/299 39/18639 0.0256410256410256 1.59840493954206 0.468124086999384 0.679282684715097 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/299 39/18639 0.0256410256410256 1.59840493954206 0.468124086999384 0.679282684715097 GO:0004177 aminopeptidase activity 1/299 40/18639 0.025 1.55844481605351 0.476674135278265 0.685148638886963 GO:0015144 carbohydrate transmembrane transporter activity 1/299 40/18639 0.025 1.55844481605351 0.476674135278265 0.685148638886963 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/299 40/18639 0.025 1.55844481605351 0.476674135278265 0.685148638886963 GO:0140662 ATP-dependent protein folding chaperone 1/299 40/18639 0.025 1.55844481605351 0.476674135278265 0.685148638886963 GO:0017080 sodium channel regulator activity 1/299 41/18639 0.024390243902439 1.52043396688147 0.485087191547516 0.693960029319741 GO:0140828 metal cation:monoatomic cation antiporter activity 1/299 41/18639 0.024390243902439 1.52043396688147 0.485087191547516 0.693960029319741 GO:0015171 amino acid transmembrane transporter activity 2/299 102/18639 0.0196078431372549 1.22230965964981 0.488883830321728 0.697749692102372 GO:0016859 cis-trans isomerase activity 1/299 42/18639 0.0238095238095238 1.4842331581462 0.49336544349543 0.699221887284898 GO:0031492 nucleosomal DNA binding 1/299 42/18639 0.0238095238095238 1.4842331581462 0.49336544349543 0.699221887284898 GO:0043175 RNA polymerase core enzyme binding 1/299 42/18639 0.0238095238095238 1.4842331581462 0.49336544349543 0.699221887284898 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/299 43/18639 0.0232558139534884 1.44971610795676 0.501511043989857 0.709113290106589 GO:0000287 magnesium ion binding 4/299 230/18639 0.0173913043478261 1.08413552421114 0.50571708872404 0.713401368780085 GO:0001046 core promoter sequence-specific DNA binding 1/299 44/18639 0.0227272727272727 1.4167680145941 0.509526111630588 0.71545467868683 GO:0043014 alpha-tubulin binding 1/299 44/18639 0.0227272727272727 1.4167680145941 0.509526111630588 0.71545467868683 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 8/299 484/18639 0.0165289256198347 1.03037673788662 0.515971480728208 0.722835622771314 GO:0004843 cysteine-type deubiquitinase activity 2/299 108/18639 0.0185185185185185 1.15440356744705 0.519237209388186 0.725738444386246 GO:0004620 phospholipase activity 2/299 109/18639 0.018348623853211 1.1438127090301 0.524178459953502 0.729612051496749 GO:0030276 clathrin binding 1/299 46/18639 0.0217391304347826 1.35516940526392 0.525172954663082 0.729612051496749 GO:0030695 GTPase regulator activity 8/299 489/18639 0.016359918200409 1.01984118841948 0.527661812555743 0.729612051496749 GO:0042578 phosphoric ester hydrolase activity 6/299 363/18639 0.0165289256198347 1.03037673788662 0.527927703056194 0.729612051496749 GO:0004222 metalloendopeptidase activity 2/299 110/18639 0.0181818181818182 1.13341441167528 0.529085530844428 0.729612051496749 GO:0060589 nucleoside-triphosphatase regulator activity 8/299 490/18639 0.0163265306122449 1.01775987987168 0.529987953533076 0.729612051496749 GO:0001216 DNA-binding transcription activator activity 8/299 491/18639 0.0162932790224033 1.01568704915911 0.53230996895144 0.729612051496749 GO:0140359 ABC-type transporter activity 1/299 47/18639 0.0212765957446809 1.32633601366256 0.532808800764073 0.729612051496749 GO:0140938 histone H3 methyltransferase activity 1/299 47/18639 0.0212765957446809 1.32633601366256 0.532808800764073 0.729612051496749 GO:0043022 ribosome binding 2/299 112/18639 0.0178571428571429 1.11317486860965 0.538796435975383 0.7349349707754 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/299 48/18639 0.0208333333333333 1.29870401337793 0.540322256474677 0.7349349707754 GO:0140693 molecular condensate scaffold activity 1/299 48/18639 0.0208333333333333 1.29870401337793 0.540322256474677 0.7349349707754 GO:0046982 protein heterodimerization activity 6/299 369/18639 0.016260162601626 1.01362264458765 0.5439764740491 0.738253786209493 GO:0005543 phospholipid binding 8/299 497/18639 0.0160965794768612 1.00342523367631 0.546151932110882 0.73838334465588 GO:0035254 glutamate receptor binding 1/299 49/18639 0.0204081632653061 1.2721998498396 0.547715277039148 0.73838334465588 GO:0060590 ATPase regulator activity 1/299 49/18639 0.0204081632653061 1.2721998498396 0.547715277039148 0.73838334465588 GO:0101005 deubiquitinase activity 2/299 115/18639 0.0173913043478261 1.08413552421114 0.553102456364065 0.743284383232502 GO:0016853 isomerase activity 3/299 180/18639 0.0166666666666667 1.03896321070234 0.553795765796584 0.743284383232502 GO:0008237 metallopeptidase activity 3/299 184/18639 0.016304347826087 1.01637705394794 0.568710838847935 0.758921088357414 GO:0005080 protein kinase C binding 1/299 52/18639 0.0192307692307692 1.19880370465655 0.569190816268061 0.758921088357414 GO:0030159 signaling receptor complex adaptor activity 1/299 52/18639 0.0192307692307692 1.19880370465655 0.569190816268061 0.758921088357414 GO:0004864 protein phosphatase inhibitor activity 1/299 53/18639 0.0188679245283019 1.17618476683284 0.576121033405622 0.75943576900464 GO:0016860 intramolecular oxidoreductase activity 1/299 53/18639 0.0188679245283019 1.17618476683284 0.576121033405622 0.75943576900464 GO:0017046 peptide hormone binding 1/299 53/18639 0.0188679245283019 1.17618476683284 0.576121033405622 0.75943576900464 GO:0051018 protein kinase A binding 1/299 53/18639 0.0188679245283019 1.17618476683284 0.576121033405622 0.75943576900464 GO:0008234 cysteine-type peptidase activity 3/299 187/18639 0.0160427807486631 1.00007153971348 0.579694584279497 0.75943576900464 GO:0015485 cholesterol binding 1/299 54/18639 0.0185185185185185 1.15440356744705 0.582940134396245 0.75943576900464 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/299 54/18639 0.0185185185185185 1.15440356744705 0.582940134396245 0.75943576900464 GO:0017069 snRNA binding 1/299 54/18639 0.0185185185185185 1.15440356744705 0.582940134396245 0.75943576900464 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/299 54/18639 0.0185185185185185 1.15440356744705 0.582940134396245 0.75943576900464 GO:0050661 NADP binding 1/299 54/18639 0.0185185185185185 1.15440356744705 0.582940134396245 0.75943576900464 GO:0046943 carboxylic acid transmembrane transporter activity 3/299 188/18639 0.0159574468085106 0.994752010246922 0.583316618626919 0.75943576900464 GO:0005342 organic acid transmembrane transporter activity 3/299 189/18639 0.0158730158730159 0.989488772097468 0.586918868326518 0.762492888766075 GO:0008374 O-acyltransferase activity 1/299 55/18639 0.0181818181818182 1.13341441167528 0.589649894945909 0.764407539716659 GO:0019212 phosphatase inhibitor activity 1/299 56/18639 0.0178571428571429 1.11317486860965 0.596252062477721 0.771321816992456 GO:0019783 ubiquitin-like protein peptidase activity 2/299 127/18639 0.015748031496063 0.981697521923472 0.607155146323568 0.783758660222356 GO:0008408 3'-5' exonuclease activity 1/299 58/18639 0.0172413793103448 1.07478952831277 0.609140469452609 0.784655519972852 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/299 128/18639 0.015625 0.974028010033445 0.611429033522193 0.785938377127893 GO:0031593 polyubiquitin modification-dependent protein binding 1/299 59/18639 0.0169491525423729 1.05657275664645 0.615430066332953 0.786095546912679 GO:0036002 pre-mRNA binding 1/299 59/18639 0.0169491525423729 1.05657275664645 0.615430066332953 0.786095546912679 GO:0070063 RNA polymerase binding 1/299 59/18639 0.0169491525423729 1.05657275664645 0.615430066332953 0.786095546912679 GO:0016298 lipase activity 2/299 130/18639 0.0153846153846154 0.959042963725238 0.619870462687477 0.790107424138336 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/299 60/18639 0.0166666666666667 1.03896321070234 0.621618785932869 0.790678288383231 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 4/299 268/18639 0.0149253731343284 0.930414815554335 0.626269286513999 0.794930534865368 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/299 61/18639 0.0163934426229508 1.02193102692034 0.62770824085542 0.795097105083532 GO:0008514 organic anion transmembrane transporter activity 4/299 269/18639 0.0148698884758364 0.926956024418446 0.629180370338731 0.795304917184925 GO:0005507 copper ion binding 1/299 63/18639 0.0158730158730159 0.989488772097468 0.639595679022077 0.806079374941503 GO:0015297 antiporter activity 2/299 135/18639 0.0148148148148148 0.923522853957637 0.640355819238069 0.806079374941503 GO:0140789 histone phosphatase activity 2/299 136/18639 0.0147058823529412 0.91673224473736 0.644347409916781 0.808778070013313 GO:0004536 DNA nuclease activity 1/299 64/18639 0.015625 0.974028010033445 0.645396760631271 0.808778070013313 GO:0005516 calmodulin binding 3/299 207/18639 0.0144927536231884 0.903446270175949 0.648286332046252 0.808778070013313 GO:0016922 nuclear receptor binding 2/299 137/18639 0.0145985401459854 0.910040768498401 0.648304022512514 0.808778070013313 GO:0008017 microtubule binding 4/299 276/18639 0.0144927536231884 0.903446270175949 0.64915081935279 0.808778070013313 GO:0051015 actin filament binding 3/299 209/18639 0.0143540669856459 0.89480085132259 0.654691111773539 0.812392830271997 GO:0001217 DNA-binding transcription repressor activity 4/299 278/18639 0.0143884892086331 0.896946656721446 0.654724484923155 0.812392830271997 GO:0008235 metalloexopeptidase activity 1/299 66/18639 0.0151515151515152 0.944512009729401 0.656721210550776 0.813210786181001 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 5/299 349/18639 0.0143266475644699 0.893091585130952 0.661871839150577 0.816727178744578 GO:0042054 histone methyltransferase activity 1/299 67/18639 0.0149253731343284 0.930414815554335 0.66224753144914 0.816727178744578 GO:0005548 phospholipid transporter activity 1/299 68/18639 0.0147058823529412 0.91673224473736 0.66768517888058 0.81845279991813 GO:0030145 manganese ion binding 1/299 68/18639 0.0147058823529412 0.91673224473736 0.66768517888058 0.81845279991813 GO:1990841 promoter-specific chromatin binding 1/299 68/18639 0.0147058823529412 0.91673224473736 0.66768517888058 0.81845279991813 GO:0140297 DNA-binding transcription factor binding 7/299 488/18639 0.014344262295082 0.894189648555294 0.670179244776954 0.819857104274422 GO:0008080 N-acetyltransferase activity 1/299 69/18639 0.0144927536231884 0.903446270175949 0.673035570971189 0.820051357014996 GO:0016279 protein-lysine N-methyltransferase activity 1/299 69/18639 0.0144927536231884 0.903446270175949 0.673035570971189 0.820051357014996 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/299 70/18639 0.0142857142857143 0.890539894887721 0.678300103242574 0.822458255584412 GO:0016278 lysine N-methyltransferase activity 1/299 70/18639 0.0142857142857143 0.890539894887721 0.678300103242574 0.822458255584412 GO:0015291 secondary active transmembrane transporter activity 4/299 287/18639 0.0139372822299652 0.868819409646557 0.679069151814761 0.822458255584412 GO:0043539 protein serine/threonine kinase activator activity 1/299 73/18639 0.0136986301369863 0.853942364960828 0.693592164791746 0.838377805553442 GO:0019842 vitamin binding 2/299 150/18639 0.0133333333333333 0.831170568561873 0.696606052317737 0.840350158351556 GO:0031491 nucleosome binding 1/299 74/18639 0.0135135135135135 0.842402603272169 0.698526773362643 0.840998570701954 GO:0003724 RNA helicase activity 1/299 77/18639 0.012987012987013 0.809581722625201 0.712860394388123 0.856406322252603 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/299 229/18639 0.0131004366812227 0.816652305355552 0.71414145622051 0.856406322252603 GO:0005085 guanyl-nucleotide exchange factor activity 3/299 230/18639 0.0130434782608696 0.813101643158354 0.716895963279935 0.857914705948812 GO:0008186 ATP-dependent activity, acting on RNA 1/299 79/18639 0.0126582278481013 0.789085982811905 0.722036726234072 0.857914705948812 GO:0015370 solute:sodium symporter activity 1/299 79/18639 0.0126582278481013 0.789085982811905 0.722036726234072 0.857914705948812 GO:0033192 calmodulin-dependent protein phosphatase activity 1/299 81/18639 0.0123456790123457 0.76960237829803 0.730920752765599 0.857914705948812 GO:0140791 histone H2AXS140 phosphatase activity 1/299 81/18639 0.0123456790123457 0.76960237829803 0.730920752765599 0.857914705948812 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/299 81/18639 0.0123456790123457 0.76960237829803 0.730920752765599 0.857914705948812 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/299 81/18639 0.0123456790123457 0.76960237829803 0.730920752765599 0.857914705948812 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/299 81/18639 0.0123456790123457 0.76960237829803 0.730920752765599 0.857914705948812 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/299 81/18639 0.0123456790123457 0.76960237829803 0.730920752765599 0.857914705948812 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/299 81/18639 0.0123456790123457 0.76960237829803 0.730920752765599 0.857914705948812 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/299 81/18639 0.0123456790123457 0.76960237829803 0.730920752765599 0.857914705948812 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/299 82/18639 0.0121951219512195 0.760216983440737 0.735256063409154 0.859684012601472 GO:0033549 MAP kinase phosphatase activity 1/299 82/18639 0.0121951219512195 0.760216983440737 0.735256063409154 0.859684012601472 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/299 83/18639 0.0120481927710843 0.751057742676391 0.739521754902427 0.862941061941878 GO:0004860 protein kinase inhibitor activity 1/299 84/18639 0.0119047619047619 0.742116579073101 0.743718941542014 0.862941061941878 GO:0017018 myosin phosphatase activity 1/299 84/18639 0.0119047619047619 0.742116579073101 0.743718941542014 0.862941061941878 GO:0051117 ATPase binding 1/299 84/18639 0.0119047619047619 0.742116579073101 0.743718941542014 0.862941061941878 GO:0140098 catalytic activity, acting on RNA 5/299 387/18639 0.0129198966408269 0.805397837753753 0.746935067218903 0.865021944512559 GO:0004197 cysteine-type endopeptidase activity 1/299 88/18639 0.0113636363636364 0.708384007297051 0.7598443092429 0.878299125512706 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/299 91/18639 0.010989010989011 0.68503068837517 0.771271050381647 0.887433208157381 GO:0019001 guanyl nucleotide binding 5/299 400/18639 0.0125 0.779222408026756 0.772125274860616 0.887433208157381 GO:0032561 guanyl ribonucleotide binding 5/299 400/18639 0.0125 0.779222408026756 0.772125274860616 0.887433208157381 GO:0004721 phosphoprotein phosphatase activity 2/299 175/18639 0.0114285714285714 0.712431915910177 0.774066445756559 0.887985658528279 GO:0042562 hormone binding 1/299 94/18639 0.0106382978723404 0.663168006831282 0.782155832646489 0.895575793312741 GO:0008276 protein methyltransferase activity 1/299 95/18639 0.0105263157894737 0.6561872909699 0.785668121998806 0.897906425141492 GO:0016407 acetyltransferase activity 1/299 96/18639 0.0104166666666667 0.649352006688963 0.789123969255188 0.899346117167773 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2/299 181/18639 0.0110497237569061 0.688815388310944 0.789886227907222 0.899346117167773 GO:0005249 voltage-gated potassium channel activity 1/299 98/18639 0.0102040816326531 0.636099924919801 0.795869939141408 0.901096690871464 GO:0008170 N-methyltransferase activity 1/299 98/18639 0.0102040816326531 0.636099924919801 0.795869939141408 0.901096690871464 GO:0042626 ATPase-coupled transmembrane transporter activity 1/299 98/18639 0.0102040816326531 0.636099924919801 0.795869939141408 0.901096690871464 GO:0016757 glycosyltransferase activity 3/299 267/18639 0.0112359550561798 0.700424636428545 0.804920872967758 0.909650354580664 GO:0140597 protein carrier chaperone 2/299 188/18639 0.0106382978723404 0.663168006831282 0.807104865116152 0.910426267144008 GO:0008238 exopeptidase activity 1/299 102/18639 0.00980392156862745 0.611154829824907 0.808723396623469 0.910562639161239 GO:0004722 protein serine/threonine phosphatase activity 1/299 103/18639 0.00970873786407767 0.605221287787772 0.811808669559197 0.911893869751409 GO:0005096 GTPase activator activity 3/299 271/18639 0.011070110701107 0.690086265411149 0.812905390469183 0.911893869751409 GO:0016791 phosphatase activity 3/299 273/18639 0.010989010989011 0.68503068837517 0.816793253361131 0.914567768036036 GO:0000149 SNARE binding 1/299 106/18639 0.00943396226415094 0.58809238341642 0.820770046541466 0.917331228487521 GO:0017124 SH3 domain binding 1/299 115/18639 0.00869565217391304 0.542067762105569 0.845181528001586 0.942881411054981 GO:0015294 solute:monoatomic cation symporter activity 1/299 116/18639 0.00862068965517241 0.537394764156383 0.847680487358503 0.943937245996282 GO:0022853 active monoatomic ion transmembrane transporter activity 1/299 118/18639 0.00847457627118644 0.528286378323224 0.852558440161114 0.947633513012719 GO:0005525 GTP binding 4/299 378/18639 0.0105820105820106 0.659659181398312 0.859213077416371 0.949286454184722 GO:0022804 active transmembrane transporter activity 5/299 457/18639 0.0109409190371991 0.682032742255366 0.860464510879881 0.949286454184722 GO:0008528 G protein-coupled peptide receptor activity 1/299 122/18639 0.00819672131147541 0.510965513460168 0.861852175509813 0.949286454184722 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/299 122/18639 0.00819672131147541 0.510965513460168 0.861852175509813 0.949286454184722 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/299 122/18639 0.00819672131147541 0.510965513460168 0.861852175509813 0.949286454184722 GO:0031625 ubiquitin protein ligase binding 3/299 302/18639 0.00993377483443709 0.619249595782852 0.865872072711557 0.950716330788745 GO:0005267 potassium channel activity 1/299 124/18639 0.00806451612903226 0.50272413421081 0.866277709304219 0.950716330788745 GO:0001653 peptide receptor activity 1/299 128/18639 0.0078125 0.487014005016722 0.874709338541908 0.958240140240505 GO:0035591 signaling adaptor activity 1/299 129/18639 0.00775193798449612 0.483238702652252 0.876733103210266 0.958729724373816 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/299 130/18639 0.00769230769230769 0.479521481862619 0.878724286470133 0.959181985949445 GO:0005179 hormone activity 1/299 132/18639 0.00757575757575758 0.472256004864701 0.882610991640472 0.959977608081229 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/299 132/18639 0.00757575757575758 0.472256004864701 0.882610991640472 0.959977608081229 GO:0044389 ubiquitin-like protein ligase binding 3/299 322/18639 0.0093167701863354 0.580786887970253 0.892619575628595 0.969129824968189 GO:0140767 enzyme-substrate adaptor activity 1/299 139/18639 0.00719424460431655 0.448473328360723 0.895262337337567 0.969239176654342 GO:0003712 transcription coregulator activity 5/299 495/18639 0.0101010101010101 0.629674673152934 0.90186363012471 0.969239176654342 GO:0022843 voltage-gated monoatomic cation channel activity 1/299 143/18639 0.00699300699300699 0.435928619875108 0.901871615562298 0.969239176654342 GO:0019903 protein phosphatase binding 1/299 144/18639 0.00694444444444444 0.432901337792642 0.903457925410204 0.969239176654342 GO:0016887 ATP hydrolysis activity 4/299 417/18639 0.00959232613908873 0.597964437814297 0.904925322338757 0.969239176654342 GO:0008194 UDP-glycosyltransferase activity 1/299 145/18639 0.00689655172413793 0.429915811325107 0.905018675899653 0.969239176654342 GO:0015293 symporter activity 1/299 146/18639 0.00684931506849315 0.426971182480414 0.906554277495089 0.969239176654342 GO:0140104 molecular carrier activity 2/299 249/18639 0.00803212851405622 0.500705161784261 0.911238215196251 0.969239176654342 GO:0000510 H3-H4 histone complex chaperone activity 1/299 151/18639 0.00662251655629139 0.412833063855235 0.913868964246354 0.969239176654342 GO:0140584 chromatin extrusion motor activity 1/299 151/18639 0.00662251655629139 0.412833063855235 0.913868964246354 0.969239176654342 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/299 151/18639 0.00662251655629139 0.412833063855235 0.913868964246354 0.969239176654342 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/299 151/18639 0.00662251655629139 0.412833063855235 0.913868964246354 0.969239176654342 GO:0015616 DNA translocase activity 1/299 152/18639 0.00657894736842105 0.410117056856187 0.915261931559765 0.969239176654342 GO:0140674 ATP-dependent histone chaperone activity 1/299 152/18639 0.00657894736842105 0.410117056856187 0.915261931559765 0.969239176654342 GO:0061775 cohesin loader activity 1/299 153/18639 0.0065359477124183 0.407436553216604 0.916632445026721 0.969239176654342 GO:0004386 helicase activity 1/299 155/18639 0.00645161290322581 0.402179307368648 0.91930754763767 0.970380189173096 GO:0140658 ATP-dependent chromatin remodeler activity 1/299 158/18639 0.00632911392405063 0.394542991405952 0.923160630596784 0.971988197228382 GO:0003689 DNA clamp loader activity 1/299 160/18639 0.00625 0.389611204013378 0.925626918084265 0.971988197228382 GO:0015079 potassium ion transmembrane transporter activity 1/299 160/18639 0.00625 0.389611204013378 0.925626918084265 0.971988197228382 GO:0015081 sodium ion transmembrane transporter activity 1/299 164/18639 0.00609756097560976 0.380108491720369 0.930325299168162 0.972023213808195 GO:0140713 histone chaperone activity 1/299 164/18639 0.00609756097560976 0.380108491720369 0.930325299168162 0.972023213808195 GO:0015399 primary active transmembrane transporter activity 1/299 166/18639 0.00602409638554217 0.375528871338196 0.932562345060288 0.972023213808195 GO:0046873 metal ion transmembrane transporter activity 4/299 450/18639 0.00888888888888889 0.554113712374582 0.932821619839701 0.972023213808195 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/299 167/18639 0.00598802395209581 0.373280195461919 0.933653876421029 0.972023213808195 GO:0005244 voltage-gated monoatomic ion channel activity 1/299 173/18639 0.00578034682080925 0.360334061515263 0.93984302496527 0.975127234093658 GO:0140030 modification-dependent protein binding 1/299 173/18639 0.00578034682080925 0.360334061515263 0.93984302496527 0.975127234093658 GO:0022832 voltage-gated channel activity 1/299 175/18639 0.00571428571428571 0.356215957955088 0.94177541889906 0.975467554839231 GO:0035091 phosphatidylinositol binding 2/299 284/18639 0.00704225352112676 0.438998539733384 0.944275802332694 0.976394026901834 GO:0015078 proton transmembrane transporter activity 1/299 185/18639 0.00540540540540541 0.336961041308867 0.950547864389751 0.979547629744015 GO:1901981 phosphatidylinositol phosphate binding 1/299 185/18639 0.00540540540540541 0.336961041308867 0.950547864389751 0.979547629744015 GO:0019902 phosphatase binding 1/299 190/18639 0.00526315789473684 0.32809364548495 0.954426764793344 0.981880664965065 GO:0016758 hexosyltransferase activity 1/299 197/18639 0.0050761421319797 0.316435495645383 0.959353018131282 0.983704032713515 GO:0016755 aminoacyltransferase activity 4/299 496/18639 0.00806451612903226 0.50272413421081 0.959435018748544 0.983704032713515 GO:0003714 transcription corepressor activity 1/299 204/18639 0.00490196078431373 0.305577414912453 0.963748353866661 0.984805040589798 GO:0008168 methyltransferase activity 1/299 204/18639 0.00490196078431373 0.305577414912453 0.963748353866661 0.984805040589798 GO:0008094 ATP-dependent activity, acting on DNA 1/299 210/18639 0.00476190476190476 0.29684663162924 0.967136630032328 0.986609179630295 GO:0016741 transferase activity, transferring one-carbon groups 1/299 215/18639 0.00465116279069767 0.289943221591351 0.969717733358094 0.986930744105764 GO:0003924 GTPase activity 2/299 331/18639 0.00604229607250755 0.376663399650396 0.970698330551393 0.986930744105764 GO:0140097 catalytic activity, acting on DNA 2/299 336/18639 0.00595238095238095 0.37105828953655 0.972663097581829 0.987277401218284 GO:0004842 ubiquitin-protein transferase activity 3/299 449/18639 0.0066815144766147 0.416510863978667 0.976560069572164 0.989410662783145 GO:0061630 ubiquitin protein ligase activity 2/299 353/18639 0.0056657223796034 0.353188626867651 0.978438173910108 0.989410662783145 GO:0042393 histone binding 1/299 247/18639 0.00404858299595142 0.252379727296115 0.982068931413349 0.989410662783145 GO:0061659 ubiquitin-like protein ligase activity 2/299 372/18639 0.00537634408602151 0.335149422807207 0.983499400351379 0.989410662783145 GO:0019787 ubiquitin-like protein transferase activity 3/299 479/18639 0.00626304801670146 0.390424588572905 0.983995162724621 0.989410662783145 GO:0003713 transcription coactivator activity 1/299 256/18639 0.00390625 0.243507002508361 0.984528702275992 0.989410662783145 GO:0022836 gated channel activity 1/299 318/18639 0.00314465408805031 0.19603079447214 0.99441234832781 0.997694237266185 GO:0005261 monoatomic cation channel activity 1/299 341/18639 0.00293255131964809 0.182808776076658 0.996173802468804 0.997814945471224 GO:0005216 monoatomic ion channel activity 1/299 448/18639 0.00223214285714286 0.139146858576206 0.999347002841874 0.999347002841874