ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	108/2221	175/18639	0.617142857142857	5.1791651122403	1.20581910109798e-55	1.48556913255271e-52
GO:0015078	proton transmembrane transporter activity	60/2221	185/18639	0.324324324324324	2.72178346739355	1.2006043119584e-13	7.39572256166371e-11
GO:0043021	ribonucleoprotein complex binding	57/2221	177/18639	0.322033898305085	2.70256183273682	6.85664145328703e-13	2.81579409014988e-10
GO:0009055	electron transfer activity	43/2221	116/18639	0.370689655172414	3.11088900619479	2.32147204120251e-12	7.15013388690373e-10
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	30/2221	68/18639	0.441176470588235	3.70242604020447	2.93838554672522e-11	7.24018198713094e-09
GO:0031625	ubiquitin protein ligase binding	77/2221	302/18639	0.254966887417219	2.13972436495702	4.66059864706036e-11	9.56976255529727e-09
GO:0044389	ubiquitin-like protein ligase binding	80/2221	322/18639	0.248447204968944	2.08501010959755	7.78786582985559e-11	1.37066438605458e-08
GO:0022853	active monoatomic ion transmembrane transporter activity	38/2221	118/18639	0.322033898305085	2.70256183273682	4.55115994661011e-09	7.00878631777957e-07
GO:0008137	NADH dehydrogenase (ubiquinone) activity	20/2221	41/18639	0.48780487804878	4.09373936152689	6.81258798513193e-09	9.32567599742504e-07
GO:0016874	ligase activity	46/2221	167/18639	0.275449101796407	2.31161450174842	2.95096918102524e-08	3.49715181452832e-06
GO:0003954	NADH dehydrogenase activity	20/2221	44/18639	0.454545454545455	3.81462076869551	3.12245697725742e-08	3.49715181452832e-06
GO:0043022	ribosome binding	35/2221	112/18639	0.3125	2.62255177847816	4.31744430743735e-08	4.12052337504647e-06
GO:0004812	aminoacyl-tRNA ligase activity	19/2221	41/18639	0.463414634146341	3.88905239345054	4.68241292618917e-08	4.12052337504647e-06
GO:0016875	ligase activity, forming carbon-oxygen bonds	19/2221	41/18639	0.463414634146341	3.88905239345054	4.68241292618917e-08	4.12052337504647e-06
GO:0019843	rRNA binding	24/2221	65/18639	0.369230769230769	3.09864579364804	1.76015228844734e-07	1.44567174624475e-05
GO:0003743	translation initiation factor activity	20/2221	51/18639	0.392156862745098	3.29104536907064	5.99881567472145e-07	4.61908806953552e-05
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	11/2221	18/18639	0.611111111111111	5.12854570013508	9.58430511612697e-07	6.24450811240553e-05
GO:0031386	protein tag activity	10/2221	15/18639	0.666666666666667	5.59477712742008	9.63032906945658e-07	6.24450811240553e-05
GO:0141047	molecular tag activity	10/2221	15/18639	0.666666666666667	5.59477712742008	9.63032906945658e-07	6.24450811240553e-05
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	21/2221	58/18639	0.362068965517241	3.03854275023677	1.48750921400833e-06	9.16305675829131e-05
GO:0061650	ubiquitin-like protein conjugating enzyme activity	17/2221	41/18639	0.414634146341463	3.47967845729785	1.66527066862165e-06	9.76958792258033e-05
GO:0030695	GTPase regulator activity	93/2221	489/18639	0.190184049079755	1.59605605168732	2.85244839608193e-06	0.000159737110180588
GO:0060589	nucleoside-triphosphatase regulator activity	93/2221	490/18639	0.189795918367347	1.59279879443898	3.11747044709556e-06	0.000166987982209641
GO:0008135	translation factor activity, RNA binding	25/2221	83/18639	0.301204819277108	2.5277607503404	7.39376344822532e-06	0.000379546523675567
GO:0015399	primary active transmembrane transporter activity	40/2221	166/18639	0.240963855421687	2.02220860027232	8.94452861287044e-06	0.000440786370042255
GO:0180051	translation factor activity	25/2221	84/18639	0.297619047619048	2.49766836045539	9.34647832461428e-06	0.000442879280612492
GO:0019787	ubiquitin-like protein transferase activity	89/2221	479/18639	0.18580375782881	1.55929592173399	1.20313719080773e-05	0.000548987044101897
GO:0015252	proton channel activity	12/2221	27/18639	0.444444444444444	3.72985141828005	2.46100196935554e-05	0.00108284086651644
GO:0016755	aminoacyltransferase activity	90/2221	496/18639	0.181451612903226	1.52277200040668	2.76221259511473e-05	0.00117346410937288
GO:0005085	guanyl-nucleotide exchange factor activity	49/2221	230/18639	0.21304347826087	1.7878961689799	3.40828523550623e-05	0.00139966913671456
GO:0016651	oxidoreductase activity, acting on NAD(P)H	24/2221	88/18639	0.272727272727273	2.28877246121731	6.78737429415957e-05	0.00269743391303374
GO:1990948	ubiquitin ligase inhibitor activity	7/2221	11/18639	0.636363636363636	5.34046907617371	7.20454166806874e-05	0.00277374854220647
GO:0061631	ubiquitin conjugating enzyme activity	13/2221	35/18639	0.371428571428571	3.11709011384833	0.000109444511561805	0.00408592843164074
GO:0055105	ubiquitin-protein transferase inhibitor activity	8/2221	15/18639	0.533333333333333	4.47582170193606	0.00011887650538366	0.00430752513625498
GO:0004842	ubiquitin-protein transferase activity	80/2221	449/18639	0.178173719376392	1.4952633748116	0.000140435228715044	0.00494332005076955
GO:0055106	ubiquitin-protein transferase regulator activity	13/2221	36/18639	0.361111111111111	3.03050427735254	0.000152735410230327	0.00522694515010453
GO:0140101	catalytic activity, acting on a tRNA	32/2221	139/18639	0.23021582733813	1.93200936774219	0.0001697168552329	0.00565111258505223
GO:0048027	mRNA 5'-UTR binding	10/2221	24/18639	0.416666666666667	3.49673570463755	0.00022738895566443	0.00723279988186539
GO:0031492	nucleosomal DNA binding	14/2221	42/18639	0.333333333333333	2.79738856371004	0.000228960385870739	0.00723279988186539
GO:0045296	cadherin binding	62/2221	334/18639	0.18562874251497	1.55782716422176	0.000246130765587423	0.00758082758009264
GO:0071889	14-3-3 protein binding	12/2221	33/18639	0.363636363636364	3.05169661495641	0.000253080022913556	0.00760474605437807
GO:0003714	transcription corepressor activity	42/2221	204/18639	0.205882352941176	1.72779881876208	0.000262101411894976	0.00768830808225263
GO:0003712	transcription coregulator activity	85/2221	495/18639	0.171717171717172	1.44107895706275	0.000313620603679734	0.00898559497054494
GO:0051787	misfolded protein binding	8/2221	17/18639	0.470588235294118	3.94925444288476	0.000360231879917432	0.0100864926376881
GO:0019207	kinase regulator activity	54/2221	287/18639	0.18815331010453	1.5790137537318	0.000426857775371866	0.0116864173168475
GO:0061791	GTPase motor activity	13/2221	40/18639	0.325	2.72745384961729	0.000503149569482973	0.0131889419064473
GO:1990606	membrane scission GTPase motor activity	13/2221	40/18639	0.325	2.72745384961729	0.000503149569482973	0.0131889419064473
GO:0051540	metal cluster binding	20/2221	77/18639	0.25974025974026	2.17978329639743	0.00053454080875011	0.0137198807579195
GO:0035091	phosphatidylinositol binding	53/2221	284/18639	0.186619718309859	1.56614359728837	0.0005864542630639	0.0147451357570352
GO:0031491	nucleosome binding	19/2221	74/18639	0.256756756756757	2.1547452450199	0.00084912435548021	0.0209224241190324
GO:0004129	cytochrome-c oxidase activity	7/2221	15/18639	0.466666666666667	3.91634398919406	0.0009099327853628	0.0219811214032739
GO:0061659	ubiquitin-like protein ligase activity	65/2221	372/18639	0.174731182795699	1.46637303742865	0.000956837530823564	0.0226696891918198
GO:0051536	iron-sulfur cluster binding	19/2221	76/18639	0.25	2.09804142278253	0.00120135708544468	0.0279258854578839
GO:0004126	cytidine deaminase activity	6/2221	12/18639	0.5	4.19608284556506	0.00138538743570144	0.0313848035354132
GO:0016675	oxidoreductase activity, acting on a heme group of donors	7/2221	16/18639	0.4375	3.67157248986943	0.00145205665707675	0.0313848035354132
GO:0034450	ubiquitin-ubiquitin ligase activity	7/2221	16/18639	0.4375	3.67157248986943	0.00145205665707675	0.0313848035354132
GO:0043023	ribosomal large subunit binding	7/2221	16/18639	0.4375	3.67157248986943	0.00145205665707675	0.0313848035354132
GO:0004860	protein kinase inhibitor activity	20/2221	84/18639	0.238095238095238	1.99813468836431	0.00172189393778208	0.0365343705328795
GO:0019210	kinase inhibitor activity	21/2221	90/18639	0.233333333333333	1.95817199459703	0.00175331122815064	0.0365343705328795
GO:0070566	adenylyltransferase activity	10/2221	30/18639	0.333333333333333	2.79738856371004	0.00177927129218569	0.0365343705328795
GO:0005096	GTPase activator activity	49/2221	271/18639	0.180811808118081	1.51740265263976	0.00185241500175267	0.0374127095435949
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	7/2221	17/18639	0.411764705882353	3.45559763752417	0.00221633400108827	0.0440407014409797
GO:0005484	SNAP receptor activity	11/2221	36/18639	0.305555555555556	2.56427285006754	0.00235076688849845	0.0459705524861918
GO:0019887	protein kinase regulator activity	46/2221	255/18639	0.180392156862745	1.51388086977249	0.00262302400351349	0.0504932120676348
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	8/2221	22/18639	0.363636363636364	3.05169661495641	0.00274018337913323	0.0519370142014176
GO:0061630	ubiquitin protein ligase activity	60/2221	353/18639	0.169971671388102	1.42643042908727	0.0028317674499692	0.0528596590660918
GO:0000287	magnesium ion binding	42/2221	230/18639	0.182608695652174	1.5324824305542	0.00311450715419623	0.0572697434920859
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	7/2221	18/18639	0.388888888888889	3.26361999099505	0.00325706034250846	0.0590102697348591
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	14/2221	54/18639	0.259259259259259	2.17574666066336	0.00355906197906535	0.0626086067407684
GO:0047429	nucleoside triphosphate diphosphatase activity	5/2221	10/18639	0.5	4.19608284556506	0.00359084423128062	0.0626086067407684
GO:0005525	GTP binding	63/2221	378/18639	0.166666666666667	1.39869428185502	0.00360812587548259	0.0626086067407684
GO:0051020	GTPase binding	54/2221	315/18639	0.171428571428571	1.43865697562231	0.00371356320976027	0.0635431927003423
GO:0017124	SH3 domain binding	24/2221	115/18639	0.208695652173913	1.75140849206194	0.00418555007733615	0.0704142088920796
GO:0003924	GTPase activity	56/2221	331/18639	0.169184290030211	1.41982259426975	0.00422942488475153	0.0704142088920796
GO:0015036	disulfide oxidoreductase activity	11/2221	40/18639	0.275	2.30784556506078	0.00578194205852138	0.0949780348813113
GO:0070990	snRNP binding	5/2221	11/18639	0.454545454545455	3.81462076869551	0.00594135967823508	0.0963125674156002
GO:0140098	catalytic activity, acting on RNA	63/2221	387/18639	0.162790697674419	1.36616650785839	0.00615913551397403	0.0985461682235844
GO:0019003	GDP binding	17/2221	75/18639	0.226666666666667	1.90222422332283	0.00627789015333814	0.0991584701142639
GO:1901981	phosphatidylinositol phosphate binding	34/2221	185/18639	0.183783783783784	1.54234396485635	0.00658196099250146	0.102645265098251
GO:0044390	ubiquitin-like protein conjugating enzyme binding	10/2221	36/18639	0.277777777777778	2.33115713642503	0.00773379308694902	0.119100413539015
GO:0003727	single-stranded RNA binding	19/2221	89/18639	0.213483146067416	1.79158593406149	0.007893876344345	0.120064884644852
GO:0019001	guanyl nucleotide binding	64/2221	400/18639	0.16	1.34274651058082	0.00849089581393951	0.126033537864741
GO:0032561	guanyl ribonucleotide binding	64/2221	400/18639	0.16	1.34274651058082	0.00849089581393951	0.126033537864741
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	7/2221	21/18639	0.333333333333333	2.79738856371004	0.00863332795008721	0.126622143267946
GO:0038187	pattern recognition receptor activity	12/2221	48/18639	0.25	2.09804142278253	0.00912821651785894	0.132305444117673
GO:0005543	phospholipid binding	77/2221	497/18639	0.154929577464789	1.30019468454129	0.00932333102533108	0.133562137479162
GO:0001098	basal transcription machinery binding	14/2221	60/18639	0.233333333333333	1.95817199459703	0.00962939327508771	0.134811505851228
GO:0001099	basal RNA polymerase II transcription machinery binding	14/2221	60/18639	0.233333333333333	1.95817199459703	0.00962939327508771	0.134811505851228
GO:0008200	ion channel inhibitor activity	11/2221	43/18639	0.255813953488372	2.14683308377747	0.0103013476833559	0.142598430852747
GO:0016835	carbon-oxygen lyase activity	17/2221	79/18639	0.215189873417722	1.80590907277484	0.0106924704166338	0.145527389693812
GO:0032977	membrane insertase activity	6/2221	17/18639	0.352941176470588	2.96194083216357	0.0109659529310779	0.145527389693812
GO:0035403	histone H3T6 kinase activity	42/2221	247/18639	0.17004048582996	1.42700793128528	0.011011778500813	0.145527389693812
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	8/2221	27/18639	0.296296296296296	2.4865676121867	0.0110610948275797	0.145527389693812
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	15/2221	67/18639	0.223880597014925	1.87884306517839	0.0111035508370278	0.145527389693812
GO:0140517	protein-RNA adaptor activity	7/2221	22/18639	0.318181818181818	2.67023453808686	0.0113834620831991	0.147625529331592
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	10/2221	38/18639	0.263157894736842	2.20846465556056	0.0115360581140516	0.148046079130328
GO:0000049	tRNA binding	17/2221	80/18639	0.2125	1.78333520936515	0.012110943575114	0.153821468912788
GO:0016248	channel inhibitor activity	11/2221	44/18639	0.25	2.09804142278253	0.0122920995525588	0.154529251517883
GO:0000149	SNARE binding	21/2221	106/18639	0.19811320754717	1.6625988633371	0.0128138724467806	0.159461523782158
GO:0019855	calcium channel inhibitor activity	5/2221	13/18639	0.384615384615385	3.22775603505005	0.0134962985791394	0.166274398494998
GO:0051539	4 iron, 4 sulfur cluster binding	11/2221	45/18639	0.244444444444444	2.05141828005403	0.0145621795117243	0.175888285867102
GO:0141110	transporter inhibitor activity	11/2221	45/18639	0.244444444444444	2.05141828005403	0.0145621795117243	0.175888285867102
GO:1990381	ubiquitin-specific protease binding	6/2221	18/18639	0.333333333333333	2.79738856371004	0.0148203992253626	0.176880174725204
GO:0016504	peptidase activator activity	13/2221	57/18639	0.228070175438596	1.91400270148582	0.0149314433209588	0.176880174725204
GO:0052866	phosphatidylinositol phosphate phosphatase activity	9/2221	34/18639	0.264705882352941	2.22145562412268	0.0155807369430129	0.182813980131352
GO:0004532	RNA exonuclease activity	10/2221	40/18639	0.25	2.09804142278253	0.0166030643672578	0.192971465098695
GO:0140297	DNA-binding transcription factor binding	74/2221	488/18639	0.151639344262295	1.2725825023435	0.0171146028794228	0.196263430726738
GO:0008408	3'-5' exonuclease activity	13/2221	58/18639	0.224137931034483	1.88100265490848	0.0172049111351361	0.196263430726738
GO:0000175	3'-5'-RNA exonuclease activity	9/2221	35/18639	0.257142857142857	2.15798546343346	0.0188145854122707	0.207220922879362
GO:0016530	metallochaperone activity	5/2221	14/18639	0.357142857142857	2.99720203254647	0.0189693086722257	0.207220922879362
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	24/2221	130/18639	0.184615384615385	1.54932289682402	0.0190211847212751	0.207220922879362
GO:0016922	nuclear receptor binding	25/2221	137/18639	0.182481751824818	1.53141709692156	0.0194198113736328	0.207220922879362
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	10/2221	41/18639	0.24390243902439	2.04686968076344	0.019678785614768	0.207220922879362
GO:0016829	lyase activity	34/2221	200/18639	0.17	1.42666816749212	0.0205729109970456	0.207220922879362
GO:0016769	transferase activity, transferring nitrogenous groups	8/2221	30/18639	0.266666666666667	2.23791085096803	0.0211211169983268	0.207220922879362
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	40/2221	243/18639	0.164609053497942	1.38142645121483	0.0211631500778572	0.207220922879362
GO:0000993	RNA polymerase II complex binding	9/2221	36/18639	0.25	2.09804142278253	0.0225081828540446	0.207220922879362
GO:0043178	alcohol binding	18/2221	92/18639	0.195652173913043	1.64194546130807	0.0227033959907375	0.207220922879362
GO:0003925	G protein activity	12/2221	54/18639	0.222222222222222	1.86492570914003	0.0230240970748068	0.207220922879362
GO:0051287	NAD binding	12/2221	54/18639	0.222222222222222	1.86492570914003	0.0230240970748068	0.207220922879362
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	4/2221	10/18639	0.4	3.35686627645205	0.0233417473712511	0.207220922879362
GO:0050815	phosphoserine residue binding	4/2221	10/18639	0.4	3.35686627645205	0.0233417473712511	0.207220922879362
GO:0070097	delta-catenin binding	4/2221	10/18639	0.4	3.35686627645205	0.0233417473712511	0.207220922879362
GO:0097177	mitochondrial ribosome binding	4/2221	10/18639	0.4	3.35686627645205	0.0233417473712511	0.207220922879362
GO:1905394	retromer complex binding	4/2221	10/18639	0.4	3.35686627645205	0.0233417473712511	0.207220922879362
GO:0004676	3-phosphoinositide-dependent protein kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0004711	ribosomal protein S6 kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0035175	histone H3S10 kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0035979	histone H2AXS139 kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0044022	histone H3S28 kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0044023	histone H4S1 kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0044024	histone H2AS1 kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0044025	histone H2BS14 kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0072354	histone H3T3 kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0072371	histone H2AS121 kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0072518	Rho-dependent protein serine/threonine kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0140823	histone H2BS36 kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0140855	histone H3S57 kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0140995	histone H2A kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0140997	histone H4 kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0140998	histone H2B kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:1990244	histone H2AT120 kinase activity	40/2221	245/18639	0.163265306122449	1.37014950059267	0.0238842297474589	0.207220922879362
GO:0016004	phospholipase activator activity	6/2221	20/18639	0.3	2.51764970733904	0.0251447749962906	0.214678026980337
GO:0004677	DNA-dependent protein kinase activity	40/2221	246/18639	0.16260162601626	1.36457978717563	0.0253446763067128	0.214678026980337
GO:0140857	histone H3T45 kinase activity	40/2221	246/18639	0.16260162601626	1.36457978717563	0.0253446763067128	0.214678026980337
GO:0047499	calcium-independent phospholipase A2 activity	8/2221	31/18639	0.258064516129032	2.16572017835616	0.0255782158245356	0.214678026980337
GO:0050700	CARD domain binding	5/2221	15/18639	0.333333333333333	2.79738856371004	0.025719873593806	0.214678026980337
GO:0032182	ubiquitin-like protein binding	22/2221	120/18639	0.183333333333333	1.53856371004052	0.0257892435008846	0.214678026980337
GO:0043130	ubiquitin binding	19/2221	100/18639	0.19	1.59451148131472	0.0260843389189832	0.21567721844421
GO:0140313	molecular sequestering activity	12/2221	55/18639	0.218181818181818	1.83101796897384	0.0263577880794873	0.216485299426189
GO:0051087	protein-folding chaperone binding	24/2221	134/18639	0.17910447761194	1.50307445214271	0.026623147254363	0.217216671638246
GO:0035402	histone H3T11 kinase activity	40/2221	247/18639	0.161943319838057	1.35905517265265	0.0268744755992342	0.217824696962214
GO:0004679	AMP-activated protein kinase activity	40/2221	248/18639	0.161290322580645	1.3535751114726	0.0284756879139983	0.229294428170235
GO:0030515	snoRNA binding	8/2221	32/18639	0.25	2.09804142278253	0.0306506268684559	0.243623047109275
GO:0051059	NF-kappaB binding	8/2221	32/18639	0.25	2.09804142278253	0.0306506268684559	0.243623047109275
GO:0022804	active transmembrane transporter activity	68/2221	457/18639	0.148796498905908	1.24872487307844	0.0310494790996016	0.245211270837879
GO:0001846	opsonin binding	6/2221	21/18639	0.285714285714286	2.39776162603718	0.0317493538147718	0.247564581644297
GO:0051010	microtubule plus-end binding	6/2221	21/18639	0.285714285714286	2.39776162603718	0.0317493538147718	0.247564581644297
GO:0106310	protein serine kinase activity	55/2221	361/18639	0.152354570637119	1.27858480058769	0.0329484284988202	0.25529851516067
GO:0019206	nucleoside kinase activity	4/2221	11/18639	0.363636363636364	3.05169661495641	0.0332848260529746	0.256293160607904
GO:0000062	fatty-acyl-CoA binding	5/2221	16/18639	0.3125	2.62255177847816	0.0338298833490551	0.25727417460516
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	5/2221	16/18639	0.3125	2.62255177847816	0.0338298833490551	0.25727417460516
GO:0008320	protein transmembrane transporter activity	7/2221	27/18639	0.259259259259259	2.17574666066336	0.0349560460536399	0.264207660969842
GO:0019239	deaminase activity	8/2221	33/18639	0.242424242424242	2.03446440997094	0.036371113594804	0.27322690212682
GO:0140996	histone H3 kinase activity	54/2221	357/18639	0.151260504201681	1.26940321378439	0.038551572704167	0.28785174285778
GO:0070034	telomerase RNA binding	6/2221	22/18639	0.272727272727273	2.28877246121731	0.0393865632141117	0.292314734215576
GO:0004721	phosphoprotein phosphatase activity	29/2221	175/18639	0.165714285714286	1.39070174310156	0.0410403392741545	0.302764658597356
GO:0046625	sphingolipid binding	7/2221	28/18639	0.25	2.09804142278253	0.0419735510719961	0.305229908003415
GO:0051537	2 iron, 2 sulfur cluster binding	7/2221	28/18639	0.25	2.09804142278253	0.0419735510719961	0.305229908003415
GO:0015035	protein-disulfide reductase activity	8/2221	34/18639	0.235294117647059	1.97462722144238	0.0427681525645858	0.305229908003415
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	8/2221	34/18639	0.235294117647059	1.97462722144238	0.0427681525645858	0.305229908003415
GO:0019902	phosphatase binding	31/2221	190/18639	0.163157894736842	1.36924808644755	0.0428152151052147	0.305229908003415
GO:0008429	phosphatidylethanolamine binding	5/2221	17/18639	0.294117647058824	2.46828402680298	0.0433565210232123	0.305229908003415
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	5/2221	17/18639	0.294117647058824	2.46828402680298	0.0433565210232123	0.305229908003415
GO:1901567	fatty acid derivative binding	5/2221	17/18639	0.294117647058824	2.46828402680298	0.0433565210232123	0.305229908003415
GO:0035173	histone kinase activity	54/2221	360/18639	0.15	1.25882485366952	0.0440170985702643	0.306956492171241
GO:0003713	transcription coactivator activity	40/2221	256/18639	0.15625	1.31127588923908	0.0441000804499266	0.306956492171241
GO:0005049	nuclear export signal receptor activity	4/2221	12/18639	0.333333333333333	2.79738856371004	0.0453294262965824	0.308667121574533
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	4/2221	12/18639	0.333333333333333	2.79738856371004	0.0453294262965824	0.308667121574533
GO:0097371	MDM2/MDM4 family protein binding	4/2221	12/18639	0.333333333333333	2.79738856371004	0.0453294262965824	0.308667121574533
GO:0005246	calcium channel regulator activity	11/2221	53/18639	0.207547169811321	1.74177023778172	0.0453480105559987	0.308667121574533
GO:0017134	fibroblast growth factor binding	6/2221	23/18639	0.260869565217391	2.18926061507742	0.0480941049880607	0.321986110234241
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	6/2221	23/18639	0.260869565217391	2.18926061507742	0.0480941049880607	0.321986110234241
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	12/2221	60/18639	0.2	1.67843313822602	0.0484080273020198	0.321986110234241
GO:0031490	chromatin DNA binding	22/2221	128/18639	0.171875	1.44240347816299	0.0487951677582658	0.321986110234241
GO:0042287	MHC protein binding	9/2221	41/18639	0.219512195121951	1.8421827126871	0.0488728917319831	0.321986110234241
GO:0140318	protein transporter activity	9/2221	41/18639	0.219512195121951	1.8421827126871	0.0488728917319831	0.321986110234241
GO:0016791	phosphatase activity	42/2221	273/18639	0.153846153846154	1.29110241402002	0.0493801297777498	0.323597446203127
GO:0004623	phospholipase A2 activity	8/2221	35/18639	0.228571428571429	1.91820930082974	0.0498655057949014	0.324550745469016
GO:0042578	phosphoric ester hydrolase activity	54/2221	363/18639	0.148760330578512	1.24842134248217	0.0500524688629164	0.324550745469016
GO:0044325	transmembrane transporter binding	23/2221	136/18639	0.169117647058824	1.41926331541171	0.0522748883936456	0.335973112474078
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	52/2221	349/18639	0.148997134670487	1.25040864165836	0.0523594460998562	0.335973112474078
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	12/2221	61/18639	0.19672131147541	1.65091784087806	0.0539931066419872	0.342884058674888
GO:0016836	hydro-lyase activity	12/2221	61/18639	0.19672131147541	1.65091784087806	0.0539931066419872	0.342884058674888
GO:0031267	small GTPase binding	43/2221	283/18639	0.151943462897526	1.27513471632012	0.0558428815945341	0.351295602084884
GO:0043175	RNA polymerase core enzyme binding	9/2221	42/18639	0.214285714285714	1.79832121952788	0.0558879366953225	0.351295602084884
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	6/2221	24/18639	0.25	2.09804142278253	0.057896559956888	0.35207373008213
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	6/2221	24/18639	0.25	2.09804142278253	0.057896559956888	0.35207373008213
GO:0004622	lysophospholipase activity	6/2221	24/18639	0.25	2.09804142278253	0.057896559956888	0.35207373008213
GO:0030552	cAMP binding	6/2221	24/18639	0.25	2.09804142278253	0.057896559956888	0.35207373008213
GO:0060229	lipase activator activity	6/2221	24/18639	0.25	2.09804142278253	0.057896559956888	0.35207373008213
GO:0070300	phosphatidic acid binding	6/2221	24/18639	0.25	2.09804142278253	0.057896559956888	0.35207373008213
GO:0001965	G-protein alpha-subunit binding	7/2221	30/18639	0.233333333333333	1.95817199459703	0.0585836969698349	0.35207373008213
GO:0031624	ubiquitin conjugating enzyme binding	7/2221	30/18639	0.233333333333333	1.95817199459703	0.0585836969698349	0.35207373008213
GO:0035925	mRNA 3'-UTR AU-rich region binding	7/2221	30/18639	0.233333333333333	1.95817199459703	0.0585836969698349	0.35207373008213
GO:0004535	poly(A)-specific ribonuclease activity	4/2221	13/18639	0.307692307692308	2.58220482804004	0.0594774830598903	0.35399158999896
GO:0140333	glycerophospholipid flippase activity	4/2221	13/18639	0.307692307692308	2.58220482804004	0.0594774830598903	0.35399158999896
GO:0004722	protein serine/threonine phosphatase activity	18/2221	103/18639	0.174757281553398	1.46659206252759	0.0609383481661635	0.36094252375343
GO:0141003	histone H2AX kinase activity	52/2221	354/18639	0.146892655367232	1.23274750265188	0.0644206195793727	0.379742599625776
GO:0016247	channel regulator activity	27/2221	168/18639	0.160714285714286	1.34874091464591	0.0648247298985484	0.380305082071484
GO:0005507	copper ion binding	12/2221	63/18639	0.19047619047619	1.59850775069145	0.0664273510340567	0.38436041901371
GO:0070003	threonine-type peptidase activity	5/2221	19/18639	0.263157894736842	2.20846465556056	0.0667639039520567	0.38436041901371
GO:0097001	ceramide binding	5/2221	19/18639	0.263157894736842	2.20846465556056	0.0667639039520567	0.38436041901371
GO:0120227	acyl-CoA binding	5/2221	19/18639	0.263157894736842	2.20846465556056	0.0667639039520567	0.38436041901371
GO:0005164	tumor necrosis factor receptor binding	7/2221	31/18639	0.225806451612903	1.89500515606164	0.0682102956372139	0.390636358195396
GO:0001848	complement binding	6/2221	25/18639	0.24	2.01411976587123	0.068805267636689	0.390636358195396
GO:0019211	phosphatase activator activity	6/2221	25/18639	0.24	2.01411976587123	0.068805267636689	0.390636358195396
GO:0001046	core promoter sequence-specific DNA binding	9/2221	44/18639	0.204545454545455	1.71657934591298	0.0717871382396268	0.405696120693671
GO:0141108	transporter regulator activity	27/2221	170/18639	0.158823529411765	1.33287337447361	0.0728469750139648	0.40980581377719
GO:0042162	telomeric DNA binding	8/2221	38/18639	0.210526315789474	1.76677172444845	0.0755199220948891	0.41439416652456
GO:0008474	palmitoyl-(protein) hydrolase activity	4/2221	14/18639	0.285714285714286	2.39776162603718	0.0756807528149562	0.41439416652456
GO:0019763	immunoglobulin receptor activity	4/2221	14/18639	0.285714285714286	2.39776162603718	0.0756807528149562	0.41439416652456
GO:0034236	protein kinase A catalytic subunit binding	4/2221	14/18639	0.285714285714286	2.39776162603718	0.0756807528149562	0.41439416652456
GO:0098599	palmitoyl hydrolase activity	4/2221	14/18639	0.285714285714286	2.39776162603718	0.0756807528149562	0.41439416652456
GO:0098847	sequence-specific single stranded DNA binding	4/2221	14/18639	0.285714285714286	2.39776162603718	0.0756807528149562	0.41439416652456
GO:0022884	macromolecule transmembrane transporter activity	7/2221	32/18639	0.21875	1.83578624493471	0.0787270028924661	0.418354745175918
GO:0047498	calcium-dependent phospholipase A2 activity	7/2221	32/18639	0.21875	1.83578624493471	0.0787270028924661	0.418354745175918
GO:0140142	nucleocytoplasmic carrier activity	7/2221	32/18639	0.21875	1.83578624493471	0.0787270028924661	0.418354745175918
GO:0120013	lipid transfer activity	12/2221	65/18639	0.184615384615385	1.54932289682402	0.0805952492071138	0.418354745175918
GO:0003697	single-stranded DNA binding	20/2221	121/18639	0.165289256198347	1.38713482498019	0.0806290898102337	0.418354745175918
GO:0004540	RNA nuclease activity	20/2221	121/18639	0.165289256198347	1.38713482498019	0.0806290898102337	0.418354745175918
GO:0016505	peptidase activator activity involved in apoptotic process	5/2221	20/18639	0.25	2.09804142278253	0.0806369469373122	0.418354745175918
GO:0042288	MHC class I protein binding	5/2221	20/18639	0.25	2.09804142278253	0.0806369469373122	0.418354745175918
GO:0004112	cyclic-nucleotide phosphodiesterase activity	6/2221	26/18639	0.230769230769231	1.93665362103003	0.080818530318075	0.418354745175918
GO:0043548	phosphatidylinositol 3-kinase binding	6/2221	26/18639	0.230769230769231	1.93665362103003	0.080818530318075	0.418354745175918
GO:0050681	nuclear androgen receptor binding	6/2221	26/18639	0.230769230769231	1.93665362103003	0.080818530318075	0.418354745175918
GO:0051139	metal cation:proton antiporter activity	6/2221	26/18639	0.230769230769231	1.93665362103003	0.080818530318075	0.418354745175918
GO:0120014	phospholipid transfer activity	6/2221	26/18639	0.230769230769231	1.93665362103003	0.080818530318075	0.418354745175918
GO:0046332	SMAD binding	14/2221	79/18639	0.177215189873418	1.48721923640281	0.0826038812446863	0.425807454784324
GO:0016779	nucleotidyltransferase activity	22/2221	136/18639	0.161764705882353	1.35755621474164	0.0837950566972405	0.428363111414939
GO:0140789	histone phosphatase activity	22/2221	136/18639	0.161764705882353	1.35755621474164	0.0837950566972405	0.428363111414939
GO:0035591	signaling adaptor activity	21/2221	129/18639	0.162790697674419	1.36616650785839	0.0850033432522951	0.432744292920775
GO:0070063	RNA polymerase binding	11/2221	59/18639	0.186440677966102	1.56464106105816	0.0867526295931618	0.439832261970269
GO:0019903	protein phosphatase binding	23/2221	144/18639	0.159722222222222	1.34041535344439	0.0876423701767889	0.442522131384442
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	7/2221	33/18639	0.212121212121212	1.78015635872457	0.090130511549529	0.448120907560443
GO:0004674	protein serine/threonine kinase activity	61/2221	433/18639	0.140877598152425	1.1822681458636	0.0927900677614512	0.448120907560443
GO:0016251	RNA polymerase II general transcription initiation factor activity	10/2221	53/18639	0.188679245283019	1.58342748889248	0.0933535937980943	0.448120907560443
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/2221	15/18639	0.266666666666667	2.23791085096803	0.0938483452590107	0.448120907560443
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/2221	15/18639	0.266666666666667	2.23791085096803	0.0938483452590107	0.448120907560443
GO:0010181	FMN binding	4/2221	15/18639	0.266666666666667	2.23791085096803	0.0938483452590107	0.448120907560443
GO:0001671	ATPase activator activity	6/2221	27/18639	0.222222222222222	1.86492570914003	0.0939220972507709	0.448120907560443
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	6/2221	27/18639	0.222222222222222	1.86492570914003	0.0939220972507709	0.448120907560443
GO:0099106	ion channel regulator activity	25/2221	160/18639	0.15625	1.31127588923908	0.0946770288683548	0.448120907560443
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	11/2221	60/18639	0.183333333333333	1.53856371004052	0.0953606015360713	0.448120907560443
GO:0008373	sialyltransferase activity	5/2221	21/18639	0.238095238095238	1.99813468836431	0.0959143197881059	0.448120907560443
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/2221	21/18639	0.238095238095238	1.99813468836431	0.0959143197881059	0.448120907560443
GO:0072542	protein phosphatase activator activity	5/2221	21/18639	0.238095238095238	1.99813468836431	0.0959143197881059	0.448120907560443
GO:0140312	cargo adaptor activity	5/2221	21/18639	0.238095238095238	1.99813468836431	0.0959143197881059	0.448120907560443
GO:0048029	monosaccharide binding	13/2221	74/18639	0.175675675675676	1.47429937817151	0.0970661564630237	0.448120907560443
GO:0033192	calmodulin-dependent protein phosphatase activity	14/2221	81/18639	0.172839506172839	1.45049777377558	0.0971171122716219	0.448120907560443
GO:0140791	histone H2AXS140 phosphatase activity	14/2221	81/18639	0.172839506172839	1.45049777377558	0.0971171122716219	0.448120907560443
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	14/2221	81/18639	0.172839506172839	1.45049777377558	0.0971171122716219	0.448120907560443
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	14/2221	81/18639	0.172839506172839	1.45049777377558	0.0971171122716219	0.448120907560443
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	14/2221	81/18639	0.172839506172839	1.45049777377558	0.0971171122716219	0.448120907560443
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	14/2221	81/18639	0.172839506172839	1.45049777377558	0.0971171122716219	0.448120907560443
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	14/2221	81/18639	0.172839506172839	1.45049777377558	0.0971171122716219	0.448120907560443
GO:1990439	MAP kinase serine/threonine phosphatase activity	14/2221	81/18639	0.172839506172839	1.45049777377558	0.0971171122716219	0.448120907560443
GO:0015485	cholesterol binding	10/2221	54/18639	0.185185185185185	1.55410475761669	0.102966051679262	0.470156482009716
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	14/2221	82/18639	0.170731707317073	1.43280877653441	0.104926184184385	0.470156482009716
GO:0033549	MAP kinase phosphatase activity	14/2221	82/18639	0.170731707317073	1.43280877653441	0.104926184184385	0.470156482009716
GO:0005548	phospholipid transporter activity	12/2221	68/18639	0.176470588235294	1.48097041608179	0.105162607795348	0.470156482009716
GO:0005522	profilin binding	3/2221	10/18639	0.3	2.51764970733904	0.106853745911299	0.470156482009716
GO:0008140	cAMP response element binding protein binding	3/2221	10/18639	0.3	2.51764970733904	0.106853745911299	0.470156482009716
GO:0031434	mitogen-activated protein kinase kinase binding	3/2221	10/18639	0.3	2.51764970733904	0.106853745911299	0.470156482009716
GO:0033204	ribonuclease P RNA binding	3/2221	10/18639	0.3	2.51764970733904	0.106853745911299	0.470156482009716
GO:0035256	G protein-coupled glutamate receptor binding	3/2221	10/18639	0.3	2.51764970733904	0.106853745911299	0.470156482009716
GO:0070513	death domain binding	3/2221	10/18639	0.3	2.51764970733904	0.106853745911299	0.470156482009716
GO:0098505	G-rich strand telomeric DNA binding	3/2221	10/18639	0.3	2.51764970733904	0.106853745911299	0.470156482009716
GO:0099122	RNA polymerase II C-terminal domain binding	3/2221	10/18639	0.3	2.51764970733904	0.106853745911299	0.470156482009716
GO:1990757	ubiquitin ligase activator activity	3/2221	10/18639	0.3	2.51764970733904	0.106853745911299	0.470156482009716
GO:0032266	phosphatidylinositol-3-phosphate binding	9/2221	48/18639	0.1875	1.5735310670869	0.111190230931501	0.480372407705901
GO:0033691	sialic acid binding	5/2221	22/18639	0.227272727272727	1.90731038434775	0.112540130545163	0.480372407705901
GO:0061133	endopeptidase activator activity	5/2221	22/18639	0.227272727272727	1.90731038434775	0.112540130545163	0.480372407705901
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	14/2221	83/18639	0.168674698795181	1.41554602019062	0.113102810929746	0.480372407705901
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	4/2221	16/18639	0.25	2.09804142278253	0.113854499228996	0.480372407705901
GO:0005521	lamin binding	4/2221	16/18639	0.25	2.09804142278253	0.113854499228996	0.480372407705901
GO:0015385	sodium:proton antiporter activity	4/2221	16/18639	0.25	2.09804142278253	0.113854499228996	0.480372407705901
GO:0017070	U6 snRNA binding	4/2221	16/18639	0.25	2.09804142278253	0.113854499228996	0.480372407705901
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	4/2221	16/18639	0.25	2.09804142278253	0.113854499228996	0.480372407705901
GO:0070411	I-SMAD binding	4/2221	16/18639	0.25	2.09804142278253	0.113854499228996	0.480372407705901
GO:0140327	flippase activity	4/2221	16/18639	0.25	2.09804142278253	0.113854499228996	0.480372407705901
GO:0140328	floppase activity	4/2221	16/18639	0.25	2.09804142278253	0.113854499228996	0.480372407705901
GO:0048487	beta-tubulin binding	8/2221	42/18639	0.19047619047619	1.59850775069145	0.120048159608341	0.504775879308791
GO:0004527	exonuclease activity	14/2221	84/18639	0.166666666666667	1.39869428185502	0.12164484020389	0.508021841122686
GO:0017018	myosin phosphatase activity	14/2221	84/18639	0.166666666666667	1.39869428185502	0.12164484020389	0.508021841122686
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	20/2221	128/18639	0.15625	1.31127588923908	0.124250270728962	0.517149775466489
GO:0002020	protease binding	21/2221	136/18639	0.154411764705882	1.29584911407156	0.128482432699137	0.532964165270494
GO:0004602	glutathione peroxidase activity	5/2221	23/18639	0.217391304347826	1.82438384589785	0.130441804311025	0.535681009703942
GO:0031681	G-protein beta-subunit binding	5/2221	23/18639	0.217391304347826	1.82438384589785	0.130441804311025	0.535681009703942
GO:0044013	histone H2B acetyltransferase activity	5/2221	23/18639	0.217391304347826	1.82438384589785	0.130441804311025	0.535681009703942
GO:0003953	NAD+ nucleosidase activity	3/2221	11/18639	0.272727272727273	2.28877246121731	0.134442090858171	0.538686773262954
GO:0008526	phosphatidylinositol transfer activity	3/2221	11/18639	0.272727272727273	2.28877246121731	0.134442090858171	0.538686773262954
GO:0034511	U3 snoRNA binding	3/2221	11/18639	0.272727272727273	2.28877246121731	0.134442090858171	0.538686773262954
GO:0050786	RAGE receptor binding	3/2221	11/18639	0.272727272727273	2.28877246121731	0.134442090858171	0.538686773262954
GO:0180030	inositol phosphate kinase activity	3/2221	11/18639	0.272727272727273	2.28877246121731	0.134442090858171	0.538686773262954
GO:0004659	prenyltransferase activity	4/2221	17/18639	0.235294117647059	1.97462722144238	0.135546184830776	0.538686773262954
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	4/2221	17/18639	0.235294117647059	1.97462722144238	0.135546184830776	0.538686773262954
GO:0005092	GDP-dissociation inhibitor activity	4/2221	17/18639	0.235294117647059	1.97462722144238	0.135546184830776	0.538686773262954
GO:0008484	sulfuric ester hydrolase activity	4/2221	17/18639	0.235294117647059	1.97462722144238	0.135546184830776	0.538686773262954
GO:0031489	myosin V binding	4/2221	17/18639	0.235294117647059	1.97462722144238	0.135546184830776	0.538686773262954
GO:0051213	dioxygenase activity	15/2221	93/18639	0.161290322580645	1.3535751114726	0.137393972985012	0.542530047171588
GO:0051219	phosphoprotein binding	15/2221	93/18639	0.161290322580645	1.3535751114726	0.137393972985012	0.542530047171588
GO:0016209	antioxidant activity	14/2221	86/18639	0.162790697674419	1.36616650785839	0.139810164565522	0.550307101420839
GO:0023023	MHC protein complex binding	7/2221	37/18639	0.189189189189189	1.58770702264624	0.144278620415734	0.56608681640823
GO:0005048	signal sequence binding	9/2221	51/18639	0.176470588235294	1.48097041608179	0.147232810718135	0.5722107974913
GO:0016830	carbon-carbon lyase activity	9/2221	51/18639	0.176470588235294	1.48097041608179	0.147232810718135	0.5722107974913
GO:0030544	Hsp70 protein binding	9/2221	51/18639	0.176470588235294	1.48097041608179	0.147232810718135	0.5722107974913
GO:0001091	RNA polymerase II general transcription initiation factor binding	5/2221	24/18639	0.208333333333333	1.74836785231878	0.149532658088429	0.573907273411044
GO:0042625	ATPase-coupled ion transmembrane transporter activity	5/2221	24/18639	0.208333333333333	1.74836785231878	0.149532658088429	0.573907273411044
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	5/2221	24/18639	0.208333333333333	1.74836785231878	0.149532658088429	0.573907273411044
GO:0046961	proton-transporting ATPase activity, rotational mechanism	5/2221	24/18639	0.208333333333333	1.74836785231878	0.149532658088429	0.573907273411044
GO:0008235	metalloexopeptidase activity	11/2221	66/18639	0.166666666666667	1.39869428185502	0.157163998911627	0.587872839681856
GO:0004706	JUN kinase kinase kinase activity	4/2221	18/18639	0.222222222222222	1.86492570914003	0.158750251215591	0.587872839681856
GO:0035615	clathrin adaptor activity	4/2221	18/18639	0.222222222222222	1.86492570914003	0.158750251215591	0.587872839681856
GO:0050811	GABA receptor binding	4/2221	18/18639	0.222222222222222	1.86492570914003	0.158750251215591	0.587872839681856
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	10/2221	59/18639	0.169491525423729	1.42240096459833	0.159089182600515	0.587872839681856
GO:0045309	protein phosphorylated amino acid binding	10/2221	59/18639	0.169491525423729	1.42240096459833	0.159089182600515	0.587872839681856
GO:0004715	non-membrane spanning protein tyrosine kinase activity	8/2221	45/18639	0.177777777777778	1.49194056731202	0.160807844580605	0.587872839681856
GO:0019209	kinase activator activity	22/2221	148/18639	0.148648648648649	1.24748408922205	0.161870923873628	0.587872839681856
GO:0004300	enoyl-CoA hydratase activity	3/2221	12/18639	0.25	2.09804142278253	0.1641463123787	0.587872839681856
GO:0004526	ribonuclease P activity	3/2221	12/18639	0.25	2.09804142278253	0.1641463123787	0.587872839681856
GO:0004875	complement receptor activity	3/2221	12/18639	0.25	2.09804142278253	0.1641463123787	0.587872839681856
GO:0005078	MAP-kinase scaffold activity	3/2221	12/18639	0.25	2.09804142278253	0.1641463123787	0.587872839681856
GO:0016208	AMP binding	3/2221	12/18639	0.25	2.09804142278253	0.1641463123787	0.587872839681856
GO:0035497	cAMP response element binding	3/2221	12/18639	0.25	2.09804142278253	0.1641463123787	0.587872839681856
GO:0042301	phosphate ion binding	3/2221	12/18639	0.25	2.09804142278253	0.1641463123787	0.587872839681856
GO:0043047	single-stranded telomeric DNA binding	3/2221	12/18639	0.25	2.09804142278253	0.1641463123787	0.587872839681856
GO:0070410	co-SMAD binding	3/2221	12/18639	0.25	2.09804142278253	0.1641463123787	0.587872839681856
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	3/2221	12/18639	0.25	2.09804142278253	0.1641463123787	0.587872839681856
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	3/2221	12/18639	0.25	2.09804142278253	0.1641463123787	0.587872839681856
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	3/2221	12/18639	0.25	2.09804142278253	0.1641463123787	0.587872839681856
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	3/2221	12/18639	0.25	2.09804142278253	0.1641463123787	0.587872839681856
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	3/2221	12/18639	0.25	2.09804142278253	0.1641463123787	0.587872839681856
GO:1990247	N6-methyladenosine-containing RNA reader activity	3/2221	12/18639	0.25	2.09804142278253	0.1641463123787	0.587872839681856
GO:0008483	transaminase activity	5/2221	25/18639	0.2	1.67843313822602	0.169714505701364	0.602559858859023
GO:0017025	TBP-class protein binding	5/2221	25/18639	0.2	1.67843313822602	0.169714505701364	0.602559858859023
GO:0120020	cholesterol transfer activity	5/2221	25/18639	0.2	1.67843313822602	0.169714505701364	0.602559858859023
GO:0016860	intramolecular oxidoreductase activity	9/2221	53/18639	0.169811320754717	1.42508474000323	0.174120837098	0.612685340289373
GO:0070717	poly-purine tract binding	6/2221	32/18639	0.1875	1.5735310670869	0.1745216239227	0.612685340289373
GO:0120015	sterol transfer activity	6/2221	32/18639	0.1875	1.5735310670869	0.1745216239227	0.612685340289373
GO:0030276	clathrin binding	8/2221	46/18639	0.173913043478261	1.45950707671828	0.175667984400826	0.612685340289373
GO:0030291	protein serine/threonine kinase inhibitor activity	8/2221	46/18639	0.173913043478261	1.45950707671828	0.175667984400826	0.612685340289373
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	7/2221	39/18639	0.179487179487179	1.50628614969002	0.176047573427304	0.612685340289373
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	7/2221	39/18639	0.179487179487179	1.50628614969002	0.176047573427304	0.612685340289373
GO:0003725	double-stranded RNA binding	12/2221	75/18639	0.16	1.34274651058082	0.17757811712367	0.616271099426369
GO:0004857	enzyme inhibitor activity	56/2221	416/18639	0.134615384615385	1.12971461226752	0.181098886107216	0.626035605156245
GO:0032934	sterol binding	11/2221	68/18639	0.161764705882353	1.35755621474164	0.181408044675957	0.626035605156245
GO:0003756	protein disulfide isomerase activity	4/2221	19/18639	0.210526315789474	1.76677172444845	0.1832799438192	0.628971840627448
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	4/2221	19/18639	0.210526315789474	1.76677172444845	0.1832799438192	0.628971840627448
GO:0019905	syntaxin binding	10/2221	61/18639	0.163934426229508	1.37576486739838	0.185045378891959	0.633266407763594
GO:0017022	myosin binding	12/2221	76/18639	0.157894736842105	1.32507879333634	0.189522689781037	0.639028796198384
GO:0051082	unfolded protein binding	18/2221	121/18639	0.148760330578512	1.24842134248217	0.190181509489568	0.639028796198384
GO:0008143	poly(A) binding	5/2221	26/18639	0.192307692307692	1.61387801752502	0.190880214125957	0.639028796198384
GO:0008198	ferrous iron binding	5/2221	26/18639	0.192307692307692	1.61387801752502	0.190880214125957	0.639028796198384
GO:0052742	phosphatidylinositol kinase activity	5/2221	26/18639	0.192307692307692	1.61387801752502	0.190880214125957	0.639028796198384
GO:0070412	R-SMAD binding	5/2221	26/18639	0.192307692307692	1.61387801752502	0.190880214125957	0.639028796198384
GO:0097602	cullin family protein binding	5/2221	26/18639	0.192307692307692	1.61387801752502	0.190880214125957	0.639028796198384
GO:0004177	aminopeptidase activity	7/2221	40/18639	0.175	1.46862899594777	0.192958657370608	0.639028796198384
GO:0030331	nuclear estrogen receptor binding	7/2221	40/18639	0.175	1.46862899594777	0.192958657370608	0.639028796198384
GO:0032451	demethylase activity	7/2221	40/18639	0.175	1.46862899594777	0.192958657370608	0.639028796198384
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	7/2221	40/18639	0.175	1.46862899594777	0.192958657370608	0.639028796198384
GO:0140311	protein sequestering activity	6/2221	33/18639	0.181818181818182	1.5258483074782	0.193275204450072	0.639028796198384
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	3/2221	13/18639	0.230769230769231	1.93665362103003	0.195546961174343	0.639028796198384
GO:0039706	co-receptor binding	3/2221	13/18639	0.230769230769231	1.93665362103003	0.195546961174343	0.639028796198384
GO:0070700	BMP receptor binding	3/2221	13/18639	0.230769230769231	1.93665362103003	0.195546961174343	0.639028796198384
GO:0140666	annealing activity	3/2221	13/18639	0.230769230769231	1.93665362103003	0.195546961174343	0.639028796198384
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	3/2221	13/18639	0.230769230769231	1.93665362103003	0.195546961174343	0.639028796198384
GO:0051117	ATPase binding	13/2221	84/18639	0.154761904761905	1.2987875474368	0.196469982734199	0.640346610392946
GO:0052689	carboxylic ester hydrolase activity	14/2221	92/18639	0.152173913043478	1.2770686921285	0.202467894276414	0.658154210418317
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	8/2221	48/18639	0.166666666666667	1.39869428185502	0.207092953778713	0.670237874340121
GO:0097110	scaffold protein binding	11/2221	70/18639	0.157142857142857	1.31876889432045	0.207273238736677	0.670237874340121
GO:0043024	ribosomal small subunit binding	4/2221	20/18639	0.2	1.67843313822602	0.208940693039671	0.672101654895235
GO:0052745	inositol phosphate phosphatase activity	4/2221	20/18639	0.2	1.67843313822602	0.208940693039671	0.672101654895235
GO:0017080	sodium channel regulator activity	7/2221	41/18639	0.170731707317073	1.43280877653441	0.210485729377076	0.672596657764695
GO:0140828	metal cation:monoatomic cation antiporter activity	7/2221	41/18639	0.170731707317073	1.43280877653441	0.210485729377076	0.672596657764695
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	6/2221	34/18639	0.176470588235294	1.48097041608179	0.212746396477215	0.672596657764695
GO:0004364	glutathione transferase activity	5/2221	27/18639	0.185185185185185	1.55410475761669	0.212916149779408	0.672596657764695
GO:0004683	calcium/calmodulin-dependent protein kinase activity	5/2221	27/18639	0.185185185185185	1.55410475761669	0.212916149779408	0.672596657764695
GO:0008266	poly(U) RNA binding	5/2221	27/18639	0.185185185185185	1.55410475761669	0.212916149779408	0.672596657764695
GO:0023026	MHC class II protein complex binding	5/2221	27/18639	0.185185185185185	1.55410475761669	0.212916149779408	0.672596657764695
GO:0060590	ATPase regulator activity	8/2221	49/18639	0.163265306122449	1.37014950059267	0.223578190351791	0.698764853060976
GO:0004065	arylsulfatase activity	3/2221	14/18639	0.214285714285714	1.79832121952788	0.228237745272358	0.698764853060976
GO:0005161	platelet-derived growth factor receptor binding	3/2221	14/18639	0.214285714285714	1.79832121952788	0.228237745272358	0.698764853060976
GO:0005545	1-phosphatidylinositol binding	3/2221	14/18639	0.214285714285714	1.79832121952788	0.228237745272358	0.698764853060976
GO:0008494	translation activator activity	3/2221	14/18639	0.214285714285714	1.79832121952788	0.228237745272358	0.698764853060976
GO:0015386	potassium:proton antiporter activity	3/2221	14/18639	0.214285714285714	1.79832121952788	0.228237745272358	0.698764853060976
GO:0019992	diacylglycerol binding	3/2221	14/18639	0.214285714285714	1.79832121952788	0.228237745272358	0.698764853060976
GO:0032036	myosin heavy chain binding	3/2221	14/18639	0.214285714285714	1.79832121952788	0.228237745272358	0.698764853060976
GO:0046030	inositol trisphosphate phosphatase activity	3/2221	14/18639	0.214285714285714	1.79832121952788	0.228237745272358	0.698764853060976
GO:0061665	SUMO ligase activity	3/2221	14/18639	0.214285714285714	1.79832121952788	0.228237745272358	0.698764853060976
GO:0071933	Arp2/3 complex binding	3/2221	14/18639	0.214285714285714	1.79832121952788	0.228237745272358	0.698764853060976
GO:0016859	cis-trans isomerase activity	7/2221	42/18639	0.166666666666667	1.39869428185502	0.228573243330822	0.698764853060976
GO:0019894	kinesin binding	7/2221	42/18639	0.166666666666667	1.39869428185502	0.228573243330822	0.698764853060976
GO:0008238	exopeptidase activity	15/2221	102/18639	0.147058823529412	1.23414201340149	0.230317737699152	0.701420061556961
GO:0005154	epidermal growth factor receptor binding	6/2221	35/18639	0.171428571428571	1.43865697562231	0.232856890447219	0.701420061556961
GO:0140566	histone reader activity	6/2221	35/18639	0.171428571428571	1.43865697562231	0.232856890447219	0.701420061556961
GO:0004601	peroxidase activity	9/2221	57/18639	0.157894736842105	1.32507879333634	0.233836481319976	0.701420061556961
GO:0019200	carbohydrate kinase activity	4/2221	21/18639	0.19047619047619	1.59850775069145	0.235535133804746	0.701420061556961
GO:0035613	RNA stem-loop binding	4/2221	21/18639	0.19047619047619	1.59850775069145	0.235535133804746	0.701420061556961
GO:0019789	SUMO transferase activity	5/2221	28/18639	0.178571428571429	1.49860101627324	0.235704468737485	0.701420061556961
GO:0046875	ephrin receptor binding	5/2221	28/18639	0.178571428571429	1.49860101627324	0.235704468737485	0.701420061556961
GO:0046966	nuclear thyroid hormone receptor binding	5/2221	28/18639	0.178571428571429	1.49860101627324	0.235704468737485	0.701420061556961
GO:0097718	disordered domain specific binding	5/2221	28/18639	0.178571428571429	1.49860101627324	0.235704468737485	0.701420061556961
GO:0141052	histone H3 demethylase activity	5/2221	28/18639	0.178571428571429	1.49860101627324	0.235704468737485	0.701420061556961
GO:0008276	protein methyltransferase activity	14/2221	95/18639	0.147368421052632	1.23674020711391	0.237885801230604	0.706205559315912
GO:0032813	tumor necrosis factor receptor superfamily binding	8/2221	50/18639	0.16	1.34274651058082	0.240521448694098	0.712313521132521
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	7/2221	43/18639	0.162790697674419	1.36616650785839	0.247163107177408	0.728480736943939
GO:0048156	tau protein binding	7/2221	43/18639	0.162790697674419	1.36616650785839	0.247163107177408	0.728480736943939
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	6/2221	36/18639	0.166666666666667	1.39869428185502	0.253525708978366	0.729397710625283
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	6/2221	36/18639	0.166666666666667	1.39869428185502	0.253525708978366	0.729397710625283
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	6/2221	36/18639	0.166666666666667	1.39869428185502	0.253525708978366	0.729397710625283
GO:0030971	receptor tyrosine kinase binding	12/2221	81/18639	0.148148148148148	1.24328380609335	0.254278217543965	0.729397710625283
GO:0003785	actin monomer binding	5/2221	29/18639	0.172413793103448	1.44692511916037	0.259125218340979	0.729397710625283
GO:0043236	laminin binding	5/2221	29/18639	0.172413793103448	1.44692511916037	0.259125218340979	0.729397710625283
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	5/2221	29/18639	0.172413793103448	1.44692511916037	0.259125218340979	0.729397710625283
GO:0008252	nucleotidase activity	3/2221	15/18639	0.2	1.67843313822602	0.261835095275695	0.729397710625283
GO:0017081	chloride channel regulator activity	3/2221	15/18639	0.2	1.67843313822602	0.261835095275695	0.729397710625283
GO:0141050	histone H3K deacetylase activity	3/2221	15/18639	0.2	1.67843313822602	0.261835095275695	0.729397710625283
GO:0141051	histone H4K deacetylase activity	3/2221	15/18639	0.2	1.67843313822602	0.261835095275695	0.729397710625283
GO:0008970	phospholipase A1 activity	4/2221	22/18639	0.181818181818182	1.5258483074782	0.26286735675132	0.729397710625283
GO:0032931	histone H3K56 acetyltransferase activity	4/2221	22/18639	0.181818181818182	1.5258483074782	0.26286735675132	0.729397710625283
GO:0043992	histone H3K9 acetyltransferase activity	4/2221	22/18639	0.181818181818182	1.5258483074782	0.26286735675132	0.729397710625283
GO:0043993	histone H3K18 acetyltransferase activity	4/2221	22/18639	0.181818181818182	1.5258483074782	0.26286735675132	0.729397710625283
GO:0043994	histone H3K23 acetyltransferase activity	4/2221	22/18639	0.181818181818182	1.5258483074782	0.26286735675132	0.729397710625283
GO:0043999	histone H2AK5 acetyltransferase activity	4/2221	22/18639	0.181818181818182	1.5258483074782	0.26286735675132	0.729397710625283
GO:0044012	histone H2AK9 acetyltransferase activity	4/2221	22/18639	0.181818181818182	1.5258483074782	0.26286735675132	0.729397710625283
GO:0044014	histone H2BK5 acetyltransferase activity	4/2221	22/18639	0.181818181818182	1.5258483074782	0.26286735675132	0.729397710625283
GO:0044015	histone H2BK12 acetyltransferase activity	4/2221	22/18639	0.181818181818182	1.5258483074782	0.26286735675132	0.729397710625283
GO:0044016	histone H3K4 acetyltransferase activity	4/2221	22/18639	0.181818181818182	1.5258483074782	0.26286735675132	0.729397710625283
GO:0044017	histone H3K27 acetyltransferase activity	4/2221	22/18639	0.181818181818182	1.5258483074782	0.26286735675132	0.729397710625283
GO:0044018	histone H3K36 acetyltransferase activity	4/2221	22/18639	0.181818181818182	1.5258483074782	0.26286735675132	0.729397710625283
GO:0046972	histone H4K16 acetyltransferase activity	4/2221	22/18639	0.181818181818182	1.5258483074782	0.26286735675132	0.729397710625283
GO:0050321	tau-protein kinase activity	4/2221	22/18639	0.181818181818182	1.5258483074782	0.26286735675132	0.729397710625283
GO:0140908	histone H3K122 acetyltransferase activity	4/2221	22/18639	0.181818181818182	1.5258483074782	0.26286735675132	0.729397710625283
GO:0016790	thiolester hydrolase activity	7/2221	44/18639	0.159090909090909	1.33511726904343	0.266195365538686	0.736972337850925
GO:0030551	cyclic nucleotide binding	6/2221	37/18639	0.162162162162162	1.36089173369678	0.274670306764682	0.758730533484503
GO:0005080	protein kinase C binding	8/2221	52/18639	0.153846153846154	1.29110241402002	0.275599625186685	0.759594492684554
GO:0044183	protein folding chaperone	11/2221	75/18639	0.146666666666667	1.23085096803242	0.277912527445554	0.762692447753841
GO:0015631	tubulin binding	50/2221	385/18639	0.12987012987013	1.08989164819872	0.277961776819379	0.762692447753841
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	17/2221	122/18639	0.139344262295082	1.16940013728862	0.282780769413941	0.769818407000672
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	9/2221	60/18639	0.15	1.25882485366952	0.28279218153469	0.769818407000672
GO:0008187	poly-pyrimidine tract binding	5/2221	30/18639	0.166666666666667	1.39869428185502	0.283058229197487	0.769818407000672
GO:0032452	histone demethylase activity	5/2221	30/18639	0.166666666666667	1.39869428185502	0.283058229197487	0.769818407000672
GO:0140303	intramembrane lipid transporter activity	7/2221	45/18639	0.155555555555556	1.30544799639802	0.285608856241491	0.775044297113473
GO:0140223	general transcription initiation factor activity	10/2221	68/18639	0.147058823529412	1.23414201340149	0.288411955535766	0.780930833450689
GO:0008171	O-methyltransferase activity	4/2221	23/18639	0.173913043478261	1.45950707671828	0.290746420422961	0.782095174587527
GO:0043274	phospholipase binding	4/2221	23/18639	0.173913043478261	1.45950707671828	0.290746420422961	0.782095174587527
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	4/2221	23/18639	0.173913043478261	1.45950707671828	0.290746420422961	0.782095174587527
GO:0051018	protein kinase A binding	8/2221	53/18639	0.150943396226415	1.26674199111398	0.293640298624673	0.785097807659227
GO:0031072	heat shock protein binding	18/2221	131/18639	0.137404580152672	1.15312200336139	0.295850961707146	0.785097807659227
GO:0004708	MAP kinase kinase activity	3/2221	16/18639	0.1875	1.5735310670869	0.295984463594163	0.785097807659227
GO:0030275	LRR domain binding	3/2221	16/18639	0.1875	1.5735310670869	0.295984463594163	0.785097807659227
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/2221	16/18639	0.1875	1.5735310670869	0.295984463594163	0.785097807659227
GO:0097027	ubiquitin-protein transferase activator activity	3/2221	16/18639	0.1875	1.5735310670869	0.295984463594163	0.785097807659227
GO:0030295	protein kinase activator activity	19/2221	139/18639	0.136690647482014	1.14713056209692	0.296960696728247	0.785097807659227
GO:0070851	growth factor receptor binding	19/2221	139/18639	0.136690647482014	1.14713056209692	0.296960696728247	0.785097807659227
GO:0008017	microtubule binding	36/2221	276/18639	0.130434782608696	1.09463030753871	0.306296500500871	0.805740546107734
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	18/2221	132/18639	0.136363636363636	1.14438623060865	0.307364592914199	0.805740546107734
GO:0070273	phosphatidylinositol-4-phosphate binding	5/2221	31/18639	0.161290322580645	1.3535751114726	0.307384786258632	0.805740546107734
GO:0140457	protein demethylase activity	5/2221	31/18639	0.161290322580645	1.3535751114726	0.307384786258632	0.805740546107734
GO:0017069	snRNA binding	8/2221	54/18639	0.148148148148148	1.24328380609335	0.311951342875617	0.808115730527661
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	8/2221	54/18639	0.148148148148148	1.24328380609335	0.311951342875617	0.808115730527661
GO:0019208	phosphatase regulator activity	16/2221	117/18639	0.136752136752137	1.14764659024002	0.31752908241764	0.808115730527661
GO:1990782	protein tyrosine kinase binding	16/2221	117/18639	0.136752136752137	1.14764659024002	0.31752908241764	0.808115730527661
GO:0035035	histone acetyltransferase binding	4/2221	24/18639	0.166666666666667	1.39869428185502	0.318989172889867	0.808115730527661
GO:0043998	histone H2A acetyltransferase activity	4/2221	24/18639	0.166666666666667	1.39869428185502	0.318989172889867	0.808115730527661
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	4/2221	24/18639	0.166666666666667	1.39869428185502	0.318989172889867	0.808115730527661
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/2221	17/18639	0.176470588235294	1.48097041608179	0.330364094757747	0.808115730527661
GO:0004549	tRNA-specific ribonuclease activity	3/2221	17/18639	0.176470588235294	1.48097041608179	0.330364094757747	0.808115730527661
GO:0016805	dipeptidase activity	3/2221	17/18639	0.176470588235294	1.48097041608179	0.330364094757747	0.808115730527661
GO:0017110	nucleoside diphosphate phosphatase activity	3/2221	17/18639	0.176470588235294	1.48097041608179	0.330364094757747	0.808115730527661
GO:0032183	SUMO binding	3/2221	17/18639	0.176470588235294	1.48097041608179	0.330364094757747	0.808115730527661
GO:0038191	neuropilin binding	3/2221	17/18639	0.176470588235294	1.48097041608179	0.330364094757747	0.808115730527661
GO:0045125	bioactive lipid receptor activity	3/2221	17/18639	0.176470588235294	1.48097041608179	0.330364094757747	0.808115730527661
GO:0048038	quinone binding	3/2221	17/18639	0.176470588235294	1.48097041608179	0.330364094757747	0.808115730527661
GO:0070402	NADPH binding	3/2221	17/18639	0.176470588235294	1.48097041608179	0.330364094757747	0.808115730527661
GO:0070403	NAD+ binding	3/2221	17/18639	0.176470588235294	1.48097041608179	0.330364094757747	0.808115730527661
GO:0031369	translation initiation factor binding	5/2221	32/18639	0.15625	1.31127588923908	0.331989075580101	0.808115730527661
GO:0042393	histone binding	32/2221	247/18639	0.129554655870445	1.08724413812212	0.333953059886644	0.808115730527661
GO:0046982	protein heterodimerization activity	47/2221	369/18639	0.127371273712737	1.06892083328758	0.334682633913194	0.808115730527661
GO:0000182	rDNA binding	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0001094	TFIID-class transcription factor complex binding	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0004090	carbonyl reductase (NADPH) activity	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0004382	GDP phosphatase activity	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0004862	cAMP-dependent protein kinase inhibitor activity	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0005345	purine nucleobase transmembrane transporter activity	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0016303	1-phosphatidylinositol-3-kinase activity	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0016783	sulfurtransferase activity	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0016868	intramolecular phosphotransferase activity	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0030957	Tat protein binding	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0042975	peroxisome proliferator activated receptor binding	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0043422	protein kinase B binding	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0050308	sugar-phosphatase activity	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0051880	G-quadruplex DNA binding	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0071723	lipopeptide binding	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/2221	10/18639	0.2	1.67843313822602	0.338464055967754	0.808115730527661
GO:0140662	ATP-dependent protein folding chaperone	6/2221	40/18639	0.15	1.25882485366952	0.340130671929655	0.80953855473127
GO:0008081	phosphoric diester hydrolase activity	12/2221	87/18639	0.137931034482759	1.15754009532829	0.340374165057466	0.80953855473127
GO:0016879	ligase activity, forming carbon-nitrogen bonds	7/2221	48/18639	0.145833333333333	1.22385749662314	0.345519798010907	0.820193431887162
GO:0004709	MAP kinase kinase kinase activity	4/2221	25/18639	0.16	1.34274651058082	0.347422442830534	0.821544049073354
GO:0005537	D-mannose binding	4/2221	25/18639	0.16	1.34274651058082	0.347422442830534	0.821544049073354
GO:0140104	molecular carrier activity	32/2221	249/18639	0.1285140562249	1.07851125347857	0.351490335436014	0.823770726790644
GO:0019956	chemokine binding	5/2221	33/18639	0.151515151515152	1.27154025623184	0.356759409710463	0.823770726790644
GO:0004518	nuclease activity	27/2221	209/18639	0.129186602870813	1.08415537636609	0.357180857810872	0.823770726790644
GO:0001530	lipopolysaccharide binding	6/2221	41/18639	0.146341463414634	1.22812180845807	0.362355519224383	0.823770726790644
GO:0016877	ligase activity, forming carbon-sulfur bonds	6/2221	41/18639	0.146341463414634	1.22812180845807	0.362355519224383	0.823770726790644
GO:0042169	SH2 domain binding	6/2221	41/18639	0.146341463414634	1.22812180845807	0.362355519224383	0.823770726790644
GO:0000400	four-way junction DNA binding	3/2221	18/18639	0.166666666666667	1.39869428185502	0.364686863466179	0.823770726790644
GO:0000900	mRNA regulatory element binding translation repressor activity	3/2221	18/18639	0.166666666666667	1.39869428185502	0.364686863466179	0.823770726790644
GO:0003746	translation elongation factor activity	3/2221	18/18639	0.166666666666667	1.39869428185502	0.364686863466179	0.823770726790644
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	3/2221	18/18639	0.166666666666667	1.39869428185502	0.364686863466179	0.823770726790644
GO:0008308	voltage-gated monoatomic anion channel activity	3/2221	18/18639	0.166666666666667	1.39869428185502	0.364686863466179	0.823770726790644
GO:0008409	5'-3' exonuclease activity	3/2221	18/18639	0.166666666666667	1.39869428185502	0.364686863466179	0.823770726790644
GO:0008525	phosphatidylcholine transporter activity	3/2221	18/18639	0.166666666666667	1.39869428185502	0.364686863466179	0.823770726790644
GO:0016854	racemase and epimerase activity	3/2221	18/18639	0.166666666666667	1.39869428185502	0.364686863466179	0.823770726790644
GO:0017075	syntaxin-1 binding	3/2221	18/18639	0.166666666666667	1.39869428185502	0.364686863466179	0.823770726790644
GO:0031690	adrenergic receptor binding	3/2221	18/18639	0.166666666666667	1.39869428185502	0.364686863466179	0.823770726790644
GO:0032393	MHC class I receptor activity	3/2221	18/18639	0.166666666666667	1.39869428185502	0.364686863466179	0.823770726790644
GO:1901611	phosphatidylglycerol binding	3/2221	18/18639	0.166666666666667	1.39869428185502	0.364686863466179	0.823770726790644
GO:0016763	pentosyltransferase activity	7/2221	49/18639	0.142857142857143	1.19888081301859	0.365843399287426	0.823770726790644
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	12/2221	89/18639	0.134831460674157	1.13152795835462	0.370322297035251	0.823770726790644
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	12/2221	89/18639	0.134831460674157	1.13152795835462	0.370322297035251	0.823770726790644
GO:0008157	protein phosphatase 1 binding	4/2221	26/18639	0.153846153846154	1.29110241402002	0.375884666231366	0.823770726790644
GO:0019865	immunoglobulin binding	4/2221	26/18639	0.153846153846154	1.29110241402002	0.375884666231366	0.823770726790644
GO:0070006	metalloaminopeptidase activity	4/2221	26/18639	0.153846153846154	1.29110241402002	0.375884666231366	0.823770726790644
GO:0016831	carboxy-lyase activity	5/2221	34/18639	0.147058823529412	1.23414201340149	0.381589239578265	0.823770726790644
GO:0000099	sulfur amino acid transmembrane transporter activity	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0001851	complement component C3b binding	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0005225	volume-sensitive anion channel activity	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0005536	D-glucose binding	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0008199	ferric iron binding	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0008432	JUN kinase binding	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0015205	nucleobase transmembrane transporter activity	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0015217	ADP transmembrane transporter activity	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0016176	superoxide-generating NADPH oxidase activator activity	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0019107	myristoyltransferase activity	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0019203	carbohydrate phosphatase activity	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0019215	intermediate filament binding	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0019864	IgG binding	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0032050	clathrin heavy chain binding	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0034713	type I transforming growth factor beta receptor binding	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0043522	leucine zipper domain binding	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0045294	alpha-catenin binding	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0047676	arachidonate-CoA ligase activity	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0048185	activin binding	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0140031	phosphorylation-dependent protein binding	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0140537	transcription regulator activator activity	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/2221	11/18639	0.181818181818182	1.5258483074782	0.38380227043655	0.823770726790644
GO:0140793	histone H2AXY142 phosphatase activity	12/2221	90/18639	0.133333333333333	1.11895542548402	0.385424221923173	0.825813289407563
GO:0003684	damaged DNA binding	10/2221	74/18639	0.135135135135135	1.13407644474731	0.386759555399391	0.826183440457877
GO:0061980	regulatory RNA binding	8/2221	58/18639	0.137931034482759	1.15754009532829	0.386938185993665	0.826183440457877
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/2221	19/18639	0.157894736842105	1.32507879333634	0.398700660899986	0.846480013011739
GO:0016918	retinal binding	3/2221	19/18639	0.157894736842105	1.32507879333634	0.398700660899986	0.846480013011739
GO:0022821	solute:potassium antiporter activity	3/2221	19/18639	0.157894736842105	1.32507879333634	0.398700660899986	0.846480013011739
GO:0140375	immune receptor activity	20/2221	156/18639	0.128205128205128	1.07591867835002	0.39919227886349	0.846480013011739
GO:0001540	amyloid-beta binding	11/2221	83/18639	0.132530120481928	1.11221473014978	0.402085562993812	0.849690246326546
GO:0030165	PDZ domain binding	11/2221	83/18639	0.132530120481928	1.11221473014978	0.402085562993812	0.849690246326546
GO:0010485	histone H4 acetyltransferase activity	5/2221	35/18639	0.142857142857143	1.19888081301859	0.406377964433439	0.856287751452832
GO:0033218	amide binding	31/2221	247/18639	0.125506072874494	1.0532677588058	0.407343052609966	0.856287751452832
GO:1990841	promoter-specific chromatin binding	9/2221	68/18639	0.132352941176471	1.11072781206134	0.42254809904164	0.856287751452832
GO:0019842	vitamin binding	19/2221	150/18639	0.126666666666667	1.06300765420982	0.42494691155385	0.856287751452832
GO:0004620	phospholipase activity	14/2221	109/18639	0.128440366972477	1.07789284106258	0.425392439697655	0.856287751452832
GO:0030159	signaling receptor complex adaptor activity	7/2221	52/18639	0.134615384615385	1.12971461226752	0.427054908471189	0.856287751452832
GO:0003995	acyl-CoA dehydrogenase activity	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0004032	aldose reductase (NADPH) activity	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0005025	transforming growth factor beta receptor activity, type I	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0005026	transforming growth factor beta receptor activity, type II	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0008603	cAMP-dependent protein kinase regulator activity	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0016273	arginine N-methyltransferase activity	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0016274	protein-arginine N-methyltransferase activity	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0016361	activin receptor activity, type I	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0016362	activin receptor activity, type II	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0016801	hydrolase activity, acting on ether bonds	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0016803	ether hydrolase activity	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0016840	carbon-nitrogen lyase activity	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0017002	activin receptor activity	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0035197	siRNA binding	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0035251	UDP-glucosyltransferase activity	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0045295	gamma-catenin binding	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0070008	serine-type exopeptidase activity	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0070679	inositol 1,4,5 trisphosphate binding	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:1990817	poly(A) RNA polymerase activity	2/2221	12/18639	0.166666666666667	1.39869428185502	0.42773346204812	0.856287751452832
GO:0019205	nucleobase-containing compound kinase activity	6/2221	44/18639	0.136363636363636	1.14438623060865	0.429172277330402	0.856287751452832
GO:0016408	C-acyltransferase activity	3/2221	20/18639	0.15	1.25882485366952	0.432187714051807	0.856287751452832
GO:0030742	GTP-dependent protein binding	3/2221	20/18639	0.15	1.25882485366952	0.432187714051807	0.856287751452832
GO:0031418	L-ascorbic acid binding	3/2221	20/18639	0.15	1.25882485366952	0.432187714051807	0.856287751452832
GO:0061608	nuclear import signal receptor activity	3/2221	20/18639	0.15	1.25882485366952	0.432187714051807	0.856287751452832
GO:0036408	histone H3K14 acetyltransferase activity	4/2221	28/18639	0.142857142857143	1.19888081301859	0.432314108282193	0.856287751452832
GO:0050698	proteoglycan sulfotransferase activity	4/2221	28/18639	0.142857142857143	1.19888081301859	0.432314108282193	0.856287751452832
GO:0051019	mitogen-activated protein kinase binding	4/2221	28/18639	0.142857142857143	1.19888081301859	0.432314108282193	0.856287751452832
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	4/2221	28/18639	0.142857142857143	1.19888081301859	0.432314108282193	0.856287751452832
GO:0019783	ubiquitin-like protein peptidase activity	16/2221	127/18639	0.125984251968504	1.05728071699277	0.446309833596187	0.880421703298915
GO:0005544	calcium-dependent phospholipid binding	7/2221	53/18639	0.132075471698113	1.10839924222473	0.447357131708702	0.880421703298915
GO:0034212	protein N-acetyltransferase activity	7/2221	53/18639	0.132075471698113	1.10839924222473	0.447357131708702	0.880421703298915
GO:0140296	general transcription initiation factor binding	7/2221	53/18639	0.132075471698113	1.10839924222473	0.447357131708702	0.880421703298915
GO:0019213	deacetylase activity	5/2221	37/18639	0.135135135135135	1.13407644474731	0.455462998907074	0.892106935961494
GO:0070001	aspartic-type peptidase activity	5/2221	37/18639	0.135135135135135	1.13407644474731	0.455462998907074	0.892106935961494
GO:0016782	transferase activity, transferring sulphur-containing groups	9/2221	70/18639	0.128571428571429	1.07899273171673	0.457932187628357	0.892106935961494
GO:0010484	histone H3 acetyltransferase activity	4/2221	29/18639	0.137931034482759	1.15754009532829	0.460024330672787	0.892106935961494
GO:0051861	glycolipid binding	4/2221	29/18639	0.137931034482759	1.15754009532829	0.460024330672787	0.892106935961494
GO:0106222	lncRNA binding	4/2221	29/18639	0.137931034482759	1.15754009532829	0.460024330672787	0.892106935961494
GO:0009975	cyclase activity	3/2221	21/18639	0.142857142857143	1.19888081301859	0.464963144092984	0.892106935961494
GO:0010314	phosphatidylinositol-5-phosphate binding	3/2221	21/18639	0.142857142857143	1.19888081301859	0.464963144092984	0.892106935961494
GO:1904047	S-adenosyl-L-methionine binding	3/2221	21/18639	0.142857142857143	1.19888081301859	0.464963144092984	0.892106935961494
GO:0050661	NADP binding	7/2221	54/18639	0.12962962962963	1.08787333033168	0.467523951322141	0.892106935961494
GO:0008234	cysteine-type peptidase activity	23/2221	187/18639	0.122994652406417	1.03219150211761	0.469090912473989	0.892106935961494
GO:0002161	aminoacyl-tRNA editing activity	2/2221	13/18639	0.153846153846154	1.29110241402002	0.469949189479716	0.892106935961494
GO:0004465	lipoprotein lipase activity	2/2221	13/18639	0.153846153846154	1.29110241402002	0.469949189479716	0.892106935961494
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/2221	13/18639	0.153846153846154	1.29110241402002	0.469949189479716	0.892106935961494
GO:0008253	5'-nucleotidase activity	2/2221	13/18639	0.153846153846154	1.29110241402002	0.469949189479716	0.892106935961494
GO:0030955	potassium ion binding	2/2221	13/18639	0.153846153846154	1.29110241402002	0.469949189479716	0.892106935961494
GO:0035325	Toll-like receptor binding	2/2221	13/18639	0.153846153846154	1.29110241402002	0.469949189479716	0.892106935961494
GO:0043560	insulin receptor substrate binding	2/2221	13/18639	0.153846153846154	1.29110241402002	0.469949189479716	0.892106935961494
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/2221	13/18639	0.153846153846154	1.29110241402002	0.469949189479716	0.892106935961494
GO:0070123	transforming growth factor beta receptor activity, type III	2/2221	13/18639	0.153846153846154	1.29110241402002	0.469949189479716	0.892106935961494
GO:0089720	caspase binding	2/2221	13/18639	0.153846153846154	1.29110241402002	0.469949189479716	0.892106935961494
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/2221	13/18639	0.153846153846154	1.29110241402002	0.469949189479716	0.892106935961494
GO:0140852	histone ubiquitin ligase activity	2/2221	13/18639	0.153846153846154	1.29110241402002	0.469949189479716	0.892106935961494
GO:0016407	acetyltransferase activity	12/2221	96/18639	0.125	1.04902071139127	0.47637269398319	0.902909475365061
GO:0030246	carbohydrate binding	34/2221	280/18639	0.121428571428571	1.0190486910658	0.480804494168468	0.908157122552134
GO:0004197	cysteine-type endopeptidase activity	11/2221	88/18639	0.125	1.04902071139127	0.481415769608	0.908157122552134
GO:0016298	lipase activity	16/2221	130/18639	0.123076923076923	1.03288193121601	0.485309596919599	0.908157122552134
GO:0001968	fibronectin binding	4/2221	30/18639	0.133333333333333	1.11895542548402	0.487249884745909	0.908157122552134
GO:0008106	alcohol dehydrogenase (NADP+) activity	4/2221	30/18639	0.133333333333333	1.11895542548402	0.487249884745909	0.908157122552134
GO:0015215	nucleotide transmembrane transporter activity	4/2221	30/18639	0.133333333333333	1.11895542548402	0.487249884745909	0.908157122552134
GO:0033612	receptor serine/threonine kinase binding	4/2221	30/18639	0.133333333333333	1.11895542548402	0.487249884745909	0.908157122552134
GO:0043995	histone H4K5 acetyltransferase activity	4/2221	30/18639	0.133333333333333	1.11895542548402	0.487249884745909	0.908157122552134
GO:0043996	histone H4K8 acetyltransferase activity	4/2221	30/18639	0.133333333333333	1.11895542548402	0.487249884745909	0.908157122552134
GO:0043997	histone H4K12 acetyltransferase activity	4/2221	30/18639	0.133333333333333	1.11895542548402	0.487249884745909	0.908157122552134
GO:0051721	protein phosphatase 2A binding	4/2221	30/18639	0.133333333333333	1.11895542548402	0.487249884745909	0.908157122552134
GO:0001784	phosphotyrosine residue binding	6/2221	47/18639	0.127659574468085	1.07134030099533	0.49477783973339	0.916388536632789
GO:0005504	fatty acid binding	6/2221	47/18639	0.127659574468085	1.07134030099533	0.49477783973339	0.916388536632789
GO:0061733	protein-lysine-acetyltransferase activity	6/2221	47/18639	0.127659574468085	1.07134030099533	0.49477783973339	0.916388536632789
GO:0004407	histone deacetylase activity	3/2221	22/18639	0.136363636363636	1.14438623060865	0.496873005252194	0.916388536632789
GO:0016881	acid-amino acid ligase activity	3/2221	22/18639	0.136363636363636	1.14438623060865	0.496873005252194	0.916388536632789
GO:0031683	G-protein beta/gamma-subunit complex binding	3/2221	22/18639	0.136363636363636	1.14438623060865	0.496873005252194	0.916388536632789
GO:0033558	protein lysine deacetylase activity	3/2221	22/18639	0.136363636363636	1.14438623060865	0.496873005252194	0.916388536632789
GO:0016776	phosphotransferase activity, phosphate group as acceptor	5/2221	39/18639	0.128205128205128	1.07591867835002	0.503348155224021	0.91767710654441
GO:0004713	protein tyrosine kinase activity	17/2221	140/18639	0.121428571428571	1.0190486910658	0.505867270937304	0.91767710654441
GO:0004725	protein tyrosine phosphatase activity	12/2221	98/18639	0.122448979591837	1.0276121254445	0.506295023845736	0.91767710654441
GO:0030527	structural constituent of chromatin	12/2221	98/18639	0.122448979591837	1.0276121254445	0.506295023845736	0.91767710654441
GO:0035401	histone H3Y41 kinase activity	14/2221	115/18639	0.121739130434783	1.0216549537028	0.50883075508002	0.91767710654441
GO:0140801	histone H2AXY142 kinase activity	14/2221	115/18639	0.121739130434783	1.0216549537028	0.50883075508002	0.91767710654441
GO:0004705	JUN kinase activity	2/2221	14/18639	0.142857142857143	1.19888081301859	0.510234430180942	0.91767710654441
GO:0005313	L-glutamate transmembrane transporter activity	2/2221	14/18639	0.142857142857143	1.19888081301859	0.510234430180942	0.91767710654441
GO:0005347	ATP transmembrane transporter activity	2/2221	14/18639	0.142857142857143	1.19888081301859	0.510234430180942	0.91767710654441
GO:0008195	phosphatidate phosphatase activity	2/2221	14/18639	0.142857142857143	1.19888081301859	0.510234430180942	0.91767710654441
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	2/2221	14/18639	0.142857142857143	1.19888081301859	0.510234430180942	0.91767710654441
GO:0032454	histone H3K9 demethylase activity	2/2221	14/18639	0.142857142857143	1.19888081301859	0.510234430180942	0.91767710654441
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/2221	14/18639	0.142857142857143	1.19888081301859	0.510234430180942	0.91767710654441
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/2221	14/18639	0.142857142857143	1.19888081301859	0.510234430180942	0.91767710654441
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/2221	14/18639	0.142857142857143	1.19888081301859	0.510234430180942	0.91767710654441
GO:0098821	BMP receptor activity	2/2221	14/18639	0.142857142857143	1.19888081301859	0.510234430180942	0.91767710654441
GO:1901612	cardiolipin binding	2/2221	14/18639	0.142857142857143	1.19888081301859	0.510234430180942	0.91767710654441
GO:0016878	acid-thiol ligase activity	4/2221	31/18639	0.129032258064516	1.08286008917808	0.513896566003284	0.922916281801816
GO:0019888	protein phosphatase regulator activity	13/2221	107/18639	0.121495327102804	1.01960891574478	0.514720885915456	0.923051137478664
GO:0160215	deacylase activity	8/2221	65/18639	0.123076923076923	1.03288193121601	0.517940581854873	0.92747499541454
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	5/2221	40/18639	0.125	1.04902071139127	0.526664938551787	0.935596741506684
GO:0000295	adenine nucleotide transmembrane transporter activity	3/2221	23/18639	0.130434782608696	1.09463030753871	0.527791992976579	0.935596741506684
GO:0003887	DNA-directed DNA polymerase activity	3/2221	23/18639	0.130434782608696	1.09463030753871	0.527791992976579	0.935596741506684
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	3/2221	23/18639	0.130434782608696	1.09463030753871	0.527791992976579	0.935596741506684
GO:0016849	phosphorus-oxygen lyase activity	3/2221	23/18639	0.130434782608696	1.09463030753871	0.527791992976579	0.935596741506684
GO:0099186	structural constituent of postsynapse	3/2221	23/18639	0.130434782608696	1.09463030753871	0.527791992976579	0.935596741506684
GO:0140102	catalytic activity, acting on a rRNA	3/2221	23/18639	0.130434782608696	1.09463030753871	0.527791992976579	0.935596741506684
GO:0001222	transcription corepressor binding	6/2221	49/18639	0.122448979591837	1.0276121254445	0.537066512634161	0.949305514440871
GO:0035254	glutamate receptor binding	6/2221	49/18639	0.122448979591837	1.0276121254445	0.537066512634161	0.949305514440871
GO:0004089	carbonate dehydratase activity	2/2221	15/18639	0.133333333333333	1.11895542548402	0.548449712474057	0.952132730805817
GO:0004467	long-chain fatty acid-CoA ligase activity	2/2221	15/18639	0.133333333333333	1.11895542548402	0.548449712474057	0.952132730805817
GO:0004559	alpha-mannosidase activity	2/2221	15/18639	0.133333333333333	1.11895542548402	0.548449712474057	0.952132730805817
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/2221	15/18639	0.133333333333333	1.11895542548402	0.548449712474057	0.952132730805817
GO:0004953	icosanoid receptor activity	2/2221	15/18639	0.133333333333333	1.11895542548402	0.548449712474057	0.952132730805817
GO:0005402	carbohydrate:monoatomic cation symporter activity	2/2221	15/18639	0.133333333333333	1.11895542548402	0.548449712474057	0.952132730805817
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/2221	15/18639	0.133333333333333	1.11895542548402	0.548449712474057	0.952132730805817
GO:0016846	carbon-sulfur lyase activity	2/2221	15/18639	0.133333333333333	1.11895542548402	0.548449712474057	0.952132730805817
GO:0033130	acetylcholine receptor binding	2/2221	15/18639	0.133333333333333	1.11895542548402	0.548449712474057	0.952132730805817
GO:0045504	dynein heavy chain binding	2/2221	15/18639	0.133333333333333	1.11895542548402	0.548449712474057	0.952132730805817
GO:0061578	K63-linked deubiquitinase activity	2/2221	15/18639	0.133333333333333	1.11895542548402	0.548449712474057	0.952132730805817
GO:0120283	protein serine/threonine kinase binding	2/2221	15/18639	0.133333333333333	1.11895542548402	0.548449712474057	0.952132730805817
GO:0015297	antiporter activity	16/2221	135/18639	0.118518518518519	0.994627044874681	0.549051920871693	0.952132730805817
GO:0001727	lipid kinase activity	5/2221	41/18639	0.121951219512195	1.02343484038172	0.549485691236149	0.952132730805817
GO:0019955	cytokine binding	17/2221	144/18639	0.118055555555556	0.990741782980639	0.554984556194507	0.956830107217284
GO:0004806	triacylglycerol lipase activity	3/2221	24/18639	0.125	1.04902071139127	0.557620967274681	0.956830107217284
GO:0005315	phosphate transmembrane transporter activity	3/2221	24/18639	0.125	1.04902071139127	0.557620967274681	0.956830107217284
GO:0015295	solute:proton symporter activity	3/2221	24/18639	0.125	1.04902071139127	0.557620967274681	0.956830107217284
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/2221	24/18639	0.125	1.04902071139127	0.557620967274681	0.956830107217284
GO:0050699	WW domain binding	3/2221	24/18639	0.125	1.04902071139127	0.557620967274681	0.956830107217284
GO:0015605	organophosphate ester transmembrane transporter activity	6/2221	50/18639	0.12	1.00705988293561	0.557633130667216	0.956830107217284
GO:0031406	carboxylic acid binding	22/2221	187/18639	0.117647058823529	0.987313610721191	0.559554909941206	0.958792279621093
GO:0003774	cytoskeletal motor activity	18/2221	153/18639	0.117647058823529	0.987313610721191	0.560602955080743	0.959253945360383
GO:0001786	phosphatidylserine binding	7/2221	59/18639	0.11864406779661	0.995680675218828	0.564809569785679	0.964341728949957
GO:0030296	protein tyrosine kinase activator activity	4/2221	33/18639	0.121212121212121	1.01723220498547	0.565141824920348	0.964341728949957
GO:0004402	histone acetyltransferase activity	5/2221	42/18639	0.119047619047619	0.999067344182157	0.571760437996893	0.970260137206848
GO:0004520	DNA endonuclease activity	5/2221	42/18639	0.119047619047619	0.999067344182157	0.571760437996893	0.970260137206848
GO:0035198	miRNA binding	5/2221	42/18639	0.119047619047619	0.999067344182157	0.571760437996893	0.970260137206848
GO:0051879	Hsp90 protein binding	5/2221	42/18639	0.119047619047619	0.999067344182157	0.571760437996893	0.970260137206848
GO:0016410	N-acyltransferase activity	11/2221	94/18639	0.117021276595745	0.982061942579057	0.573222577828825	0.971403323088188
GO:0016853	isomerase activity	21/2221	180/18639	0.116666666666667	0.979085997298514	0.575912265488097	0.974620756979857
GO:0043177	organic acid binding	22/2221	189/18639	0.116402116402116	0.976865847644776	0.580586808298688	0.974767049647805
GO:0004707	MAP kinase activity	2/2221	16/18639	0.125	1.04902071139127	0.584516176599756	0.974767049647805
GO:0005024	transforming growth factor beta receptor activity	2/2221	16/18639	0.125	1.04902071139127	0.584516176599756	0.974767049647805
GO:0005159	insulin-like growth factor receptor binding	2/2221	16/18639	0.125	1.04902071139127	0.584516176599756	0.974767049647805
GO:0008296	3'-5'-DNA exonuclease activity	2/2221	16/18639	0.125	1.04902071139127	0.584516176599756	0.974767049647805
GO:0015562	efflux transmembrane transporter activity	2/2221	16/18639	0.125	1.04902071139127	0.584516176599756	0.974767049647805
GO:0015923	mannosidase activity	2/2221	16/18639	0.125	1.04902071139127	0.584516176599756	0.974767049647805
GO:0019841	retinol binding	2/2221	16/18639	0.125	1.04902071139127	0.584516176599756	0.974767049647805
GO:0000030	mannosyltransferase activity	3/2221	25/18639	0.12	1.00705988293561	0.586284402426156	0.974767049647805
GO:0008139	nuclear localization sequence binding	3/2221	25/18639	0.12	1.00705988293561	0.586284402426156	0.974767049647805
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/2221	25/18639	0.12	1.00705988293561	0.586284402426156	0.974767049647805
GO:0047617	fatty acyl-CoA hydrolase activity	3/2221	25/18639	0.12	1.00705988293561	0.586284402426156	0.974767049647805
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	3/2221	25/18639	0.12	1.00705988293561	0.586284402426156	0.974767049647805
GO:0008080	N-acetyltransferase activity	8/2221	69/18639	0.115942028985507	0.973004717812188	0.588464590601081	0.977073282507456
GO:0030332	cyclin binding	4/2221	34/18639	0.117647058823529	0.987313610721191	0.589615502965959	0.977666621337902
GO:0008375	acetylglucosaminyltransferase activity	5/2221	43/18639	0.116279069767442	0.975833219898851	0.593446264970804	0.982695965650579
GO:0015026	coreceptor activity	7/2221	61/18639	0.114754098360656	0.963035407178866	0.601393403810575	0.993764109353823
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	14/2221	122/18639	0.114754098360656	0.963035407178866	0.601743527254831	0.993764109353823
GO:0061134	peptidase regulator activity	26/2221	226/18639	0.115044247787611	0.965470389245058	0.607046565658237	0.998522470355806
GO:0033293	monocarboxylic acid binding	9/2221	79/18639	0.113924050632911	0.95606950911609	0.60913547651417	0.998522470355806
GO:0034061	DNA polymerase activity	4/2221	35/18639	0.114285714285714	0.959104650414871	0.613259056324994	0.998522470355806
GO:0043015	gamma-tubulin binding	4/2221	35/18639	0.114285714285714	0.959104650414871	0.613259056324994	0.998522470355806
GO:0004435	phosphatidylinositol phospholipase C activity	3/2221	26/18639	0.115384615384615	0.968326810515014	0.61372784627765	0.998522470355806
GO:0005112	Notch binding	3/2221	26/18639	0.115384615384615	0.968326810515014	0.61372784627765	0.998522470355806
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/2221	26/18639	0.115384615384615	0.968326810515014	0.61372784627765	0.998522470355806
GO:0015216	purine nucleotide transmembrane transporter activity	3/2221	26/18639	0.115384615384615	0.968326810515014	0.61372784627765	0.998522470355806
GO:0016289	acyl-CoA hydrolase activity	3/2221	26/18639	0.115384615384615	0.968326810515014	0.61372784627765	0.998522470355806
GO:0050750	low-density lipoprotein particle receptor binding	3/2221	26/18639	0.115384615384615	0.968326810515014	0.61372784627765	0.998522470355806
GO:0043014	alpha-tubulin binding	5/2221	44/18639	0.113636363636364	0.953655192173877	0.61450703261701	0.998522470355806
GO:0008146	sulfotransferase activity	6/2221	53/18639	0.113207547169811	0.950056493335485	0.616576323282229	0.998522470355806
GO:1901505	carbohydrate derivative transmembrane transporter activity	6/2221	53/18639	0.113207547169811	0.950056493335485	0.616576323282229	0.998522470355806
GO:0008237	metallopeptidase activity	21/2221	184/18639	0.114130434782609	0.957801519096373	0.617896547475024	0.998522470355806
GO:0016018	cyclosporin A binding	2/2221	17/18639	0.117647058823529	0.987313610721191	0.618403120845357	0.998522470355806
GO:0030169	low-density lipoprotein particle binding	2/2221	17/18639	0.117647058823529	0.987313610721191	0.618403120845357	0.998522470355806
GO:0046965	nuclear retinoid X receptor binding	2/2221	17/18639	0.117647058823529	0.987313610721191	0.618403120845357	0.998522470355806
GO:0101005	deubiquitinase activity	13/2221	115/18639	0.11304347826087	0.948679599866883	0.623477038039018	0.999999999993352
GO:0008170	N-methyltransferase activity	11/2221	98/18639	0.112244897959184	0.941977781657463	0.630434063366465	0.999999999993352
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	26/2221	229/18639	0.11353711790393	0.952822305543158	0.634733710229523	0.999999999993352
GO:0140463	chromatin-protein adaptor activity	6/2221	54/18639	0.111111111111111	0.932462854570014	0.63520786977724	0.999999999993352
GO:0004033	aldo-keto reductase (NADPH) activity	4/2221	36/18639	0.111111111111111	0.932462854570014	0.636037494112747	0.999999999993352
GO:0004190	aspartic-type endopeptidase activity	4/2221	36/18639	0.111111111111111	0.932462854570014	0.636037494112747	0.999999999993352
GO:0004869	cysteine-type endopeptidase inhibitor activity	4/2221	36/18639	0.111111111111111	0.932462854570014	0.636037494112747	0.999999999993352
GO:0005518	collagen binding	8/2221	72/18639	0.111111111111111	0.932462854570014	0.637898924401839	0.999999999993352
GO:0042379	chemokine receptor binding	8/2221	72/18639	0.111111111111111	0.932462854570014	0.637898924401839	0.999999999993352
GO:0005385	zinc ion transmembrane transporter activity	3/2221	27/18639	0.111111111111111	0.932462854570014	0.639915449947523	0.999999999993352
GO:0008168	methyltransferase activity	23/2221	204/18639	0.112745098039216	0.946175543607808	0.644182885031415	0.999999999993352
GO:0005319	lipid transporter activity	20/2221	178/18639	0.112359550561798	0.942939965295519	0.645288953676621	0.999999999993352
GO:0004843	cysteine-type deubiquitinase activity	12/2221	108/18639	0.111111111111111	0.932462854570014	0.646398355964438	0.999999999993352
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/2221	18/18639	0.111111111111111	0.932462854570014	0.650117653017755	0.999999999993352
GO:0015172	acidic amino acid transmembrane transporter activity	2/2221	18/18639	0.111111111111111	0.932462854570014	0.650117653017755	0.999999999993352
GO:0070064	proline-rich region binding	2/2221	18/18639	0.111111111111111	0.932462854570014	0.650117653017755	0.999999999993352
GO:0070628	proteasome binding	2/2221	18/18639	0.111111111111111	0.932462854570014	0.650117653017755	0.999999999993352
GO:0098641	cadherin binding involved in cell-cell adhesion	2/2221	18/18639	0.111111111111111	0.932462854570014	0.650117653017755	0.999999999993352
GO:0008374	O-acyltransferase activity	6/2221	55/18639	0.109090909090909	0.915508984486922	0.653293460494639	0.999999999993352
GO:0004521	RNA endonuclease activity	8/2221	73/18639	0.10958904109589	0.91968939080878	0.653614413376092	0.999999999993352
GO:0004180	carboxypeptidase activity	5/2221	46/18639	0.108695652173913	0.912191922948926	0.654640665893487	0.999999999993352
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	5/2221	46/18639	0.108695652173913	0.912191922948926	0.654640665893487	0.999999999993352
GO:0043394	proteoglycan binding	4/2221	37/18639	0.108108108108108	0.907261155797851	0.657925311713435	0.999999999993352
GO:0042826	histone deacetylase binding	14/2221	127/18639	0.110236220472441	0.925120627368675	0.662939438651678	0.999999999993352
GO:0016757	glycosyltransferase activity	30/2221	267/18639	0.112359550561798	0.942939965295519	0.663224766046008	0.999999999993352
GO:0045499	chemorepellent activity	3/2221	28/18639	0.107142857142857	0.899160609763942	0.664827610947363	0.999999999993352
GO:0051959	dynein light intermediate chain binding	3/2221	28/18639	0.107142857142857	0.899160609763942	0.664827610947363	0.999999999993352
GO:0019212	phosphatase inhibitor activity	6/2221	56/18639	0.107142857142857	0.899160609763942	0.670816455431059	0.999999999993352
GO:0030170	pyridoxal phosphate binding	6/2221	56/18639	0.107142857142857	0.899160609763942	0.670816455431059	0.999999999993352
GO:0140938	histone H3 methyltransferase activity	5/2221	47/18639	0.106382978723404	0.892783584162779	0.673671954722071	0.999999999993352
GO:0005501	retinoid binding	4/2221	38/18639	0.105263157894737	0.883385862224223	0.678905630055752	0.999999999993352
GO:0019840	isoprenoid binding	4/2221	38/18639	0.105263157894737	0.883385862224223	0.678905630055752	0.999999999993352
GO:0043531	ADP binding	4/2221	38/18639	0.105263157894737	0.883385862224223	0.678905630055752	0.999999999993352
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/2221	19/18639	0.105263157894737	0.883385862224223	0.679696122678668	0.999999999993352
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/2221	19/18639	0.105263157894737	0.883385862224223	0.679696122678668	0.999999999993352
GO:0008301	DNA binding, bending	2/2221	19/18639	0.105263157894737	0.883385862224223	0.679696122678668	0.999999999993352
GO:0031420	alkali metal ion binding	2/2221	19/18639	0.105263157894737	0.883385862224223	0.679696122678668	0.999999999993352
GO:0042577	lipid phosphatase activity	2/2221	19/18639	0.105263157894737	0.883385862224223	0.679696122678668	0.999999999993352
GO:0042800	histone H3K4 methyltransferase activity	2/2221	19/18639	0.105263157894737	0.883385862224223	0.679696122678668	0.999999999993352
GO:0046527	glucosyltransferase activity	2/2221	19/18639	0.105263157894737	0.883385862224223	0.679696122678668	0.999999999993352
GO:0046624	sphingolipid transporter activity	2/2221	19/18639	0.105263157894737	0.883385862224223	0.679696122678668	0.999999999993352
GO:0050145	nucleoside monophosphate kinase activity	2/2221	19/18639	0.105263157894737	0.883385862224223	0.679696122678668	0.999999999993352
GO:0140036	ubiquitin-modified protein reader activity	2/2221	19/18639	0.105263157894737	0.883385862224223	0.679696122678668	0.999999999993352
GO:1990380	K48-linked deubiquitinase activity	2/2221	19/18639	0.105263157894737	0.883385862224223	0.679696122678668	0.999999999993352
GO:0070279	vitamin B6 binding	6/2221	57/18639	0.105263157894737	0.883385862224223	0.687763968435967	0.999999999993352
GO:0004629	phospholipase C activity	3/2221	29/18639	0.103448275862069	0.86815507149622	0.688458758671352	0.999999999993352
GO:0042562	hormone binding	10/2221	94/18639	0.106382978723404	0.892783584162779	0.696171648811303	0.999999999993352
GO:0016798	hydrolase activity, acting on glycosyl bonds	14/2221	130/18639	0.107692307692308	0.903771689814013	0.69705608693066	0.999999999993352
GO:0140767	enzyme-substrate adaptor activity	15/2221	139/18639	0.107913669064748	0.90562939112915	0.697852638129097	0.999999999993352
GO:0000217	DNA secondary structure binding	4/2221	39/18639	0.102564102564103	0.860734942680012	0.698969341465093	0.999999999993352
GO:0000339	RNA cap binding	2/2221	20/18639	0.1	0.839216569113012	0.707197056970542	0.999999999993352
GO:0001614	purinergic nucleotide receptor activity	2/2221	20/18639	0.1	0.839216569113012	0.707197056970542	0.999999999993352
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	2/2221	20/18639	0.1	0.839216569113012	0.707197056970542	0.999999999993352
GO:0016502	nucleotide receptor activity	2/2221	20/18639	0.1	0.839216569113012	0.707197056970542	0.999999999993352
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	18/2221	167/18639	0.107784431137725	0.904544805031989	0.710617746544533	0.999999999993352
GO:0098918	structural constituent of synapse	3/2221	30/18639	0.1	0.839216569113012	0.710815300218624	0.999999999993352
GO:0030145	manganese ion binding	7/2221	68/18639	0.102941176470588	0.863899409381042	0.715403135733033	0.999999999993352
GO:0015144	carbohydrate transmembrane transporter activity	4/2221	40/18639	0.1	0.839216569113012	0.718114275122127	0.999999999993352
GO:0050997	quaternary ammonium group binding	4/2221	40/18639	0.1	0.839216569113012	0.718114275122127	0.999999999993352
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0003796	lysozyme activity	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0005131	growth hormone receptor binding	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0005528	FK506 binding	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0008190	eukaryotic initiation factor 4E binding	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0015187	glycine transmembrane transporter activity	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0016427	tRNA (cytidine) methyltransferase activity	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0031419	cobalamin binding	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0031996	thioesterase binding	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0032052	bile acid binding	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0032356	oxidized DNA binding	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0032395	MHC class II receptor activity	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0043208	glycosphingolipid binding	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0043295	glutathione binding	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0051864	histone H3K36 demethylase activity	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0070739	protein-glutamic acid ligase activity	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0070740	tubulin-glutamic acid ligase activity	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0140999	histone H3K4 trimethyltransferase activity	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:1990763	arrestin family protein binding	1/2221	10/18639	0.1	0.839216569113012	0.71891702774217	0.999999999993352
GO:0015459	potassium channel regulator activity	6/2221	59/18639	0.101694915254237	0.853440578758995	0.719898379660609	0.999999999993352
GO:0031593	polyubiquitin modification-dependent protein binding	6/2221	59/18639	0.101694915254237	0.853440578758995	0.719898379660609	0.999999999993352
GO:0042277	peptide binding	27/2221	249/18639	0.108433734939759	0.909993870122543	0.728821824757086	0.999999999993352
GO:0005452	solute:inorganic anion antiporter activity	3/2221	31/18639	0.0967741935483871	0.81214506688356	0.73191373602741	0.999999999993352
GO:0008327	methyl-CpG binding	3/2221	31/18639	0.0967741935483871	0.81214506688356	0.73191373602741	0.999999999993352
GO:0070325	lipoprotein particle receptor binding	3/2221	31/18639	0.0967741935483871	0.81214506688356	0.73191373602741	0.999999999993352
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	2/2221	21/18639	0.0952380952380952	0.799253875345726	0.732695363589232	0.999999999993352
GO:0061891	calcium ion sensor activity	2/2221	21/18639	0.0952380952380952	0.799253875345726	0.732695363589232	0.999999999993352
GO:0016741	transferase activity, transferring one-carbon groups	23/2221	215/18639	0.106976744186047	0.897766562306943	0.74065079951564	0.999999999993352
GO:0042626	ATPase-coupled transmembrane transporter activity	10/2221	98/18639	0.102040816326531	0.856343437870421	0.745049319721791	0.999999999993352
GO:0015106	bicarbonate transmembrane transporter activity	3/2221	32/18639	0.09375	0.786765533543449	0.751778948338923	0.999999999993352
GO:0043425	bHLH transcription factor binding	3/2221	32/18639	0.09375	0.786765533543449	0.751778948338923	0.999999999993352
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0002162	dystroglycan binding	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0004016	adenylate cyclase activity	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0008046	axon guidance receptor activity	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0008172	S-methyltransferase activity	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0008503	benzodiazepine receptor activity	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0010854	adenylate cyclase regulator activity	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0015173	aromatic amino acid transmembrane transporter activity	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0032404	mismatch repair complex binding	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0032794	GTPase activating protein binding	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0034056	estrogen response element binding	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0042608	T cell receptor binding	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0070697	activin receptor binding	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:1900750	oligopeptide binding	1/2221	11/18639	0.0909090909090909	0.762924153739102	0.752428503472732	0.999999999993352
GO:0005496	steroid binding	11/2221	108/18639	0.101851851851852	0.854757616689179	0.753789917235797	0.999999999993352
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	19/2221	181/18639	0.104972375690608	0.88094556978714	0.75575411964682	0.999999999993352
GO:0008649	rRNA methyltransferase activity	2/2221	22/18639	0.0909090909090909	0.762924153739102	0.756277599422936	0.999999999993352
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/2221	22/18639	0.0909090909090909	0.762924153739102	0.756277599422936	0.999999999993352
GO:0034062	5'-3' RNA polymerase activity	2/2221	22/18639	0.0909090909090909	0.762924153739102	0.756277599422936	0.999999999993352
GO:0097747	RNA polymerase activity	2/2221	22/18639	0.0909090909090909	0.762924153739102	0.756277599422936	0.999999999993352
GO:0140035	ubiquitin-like protein reader activity	2/2221	22/18639	0.0909090909090909	0.762924153739102	0.756277599422936	0.999999999993352
GO:0140784	metal ion sensor activity	2/2221	22/18639	0.0909090909090909	0.762924153739102	0.756277599422936	0.999999999993352
GO:0004519	endonuclease activity	13/2221	127/18639	0.102362204724409	0.859040582556627	0.760212185167185	0.999999999993352
GO:0015179	L-amino acid transmembrane transporter activity	6/2221	62/18639	0.0967741935483871	0.81214506688356	0.763651408745472	0.999999999993352
GO:0001618	virus receptor activity	8/2221	81/18639	0.0987654320987654	0.828855870728901	0.764076717545227	0.999999999993352
GO:0004712	protein serine/threonine/tyrosine kinase activity	4/2221	43/18639	0.0930232558139535	0.780666575919081	0.770102122051921	0.999999999993352
GO:0072341	modified amino acid binding	9/2221	91/18639	0.0989010989010989	0.829994409012869	0.77114105138347	0.999999999993352
GO:0004864	protein phosphatase inhibitor activity	5/2221	53/18639	0.0943396226415094	0.791713744446238	0.772842534092824	0.999999999993352
GO:0140272	exogenous protein binding	8/2221	82/18639	0.0975609756097561	0.818747872305378	0.775910467014234	0.999999999993352
GO:0005158	insulin receptor binding	2/2221	23/18639	0.0869565217391304	0.729753538359141	0.778038133370208	0.999999999993352
GO:0042171	lysophosphatidic acid acyltransferase activity	2/2221	23/18639	0.0869565217391304	0.729753538359141	0.778038133370208	0.999999999993352
GO:0070577	lysine-acetylated histone binding	2/2221	23/18639	0.0869565217391304	0.729753538359141	0.778038133370208	0.999999999993352
GO:0071617	lysophospholipid acyltransferase activity	2/2221	23/18639	0.0869565217391304	0.729753538359141	0.778038133370208	0.999999999993352
GO:0000340	RNA 7-methylguanosine cap binding	1/2221	12/18639	0.0833333333333333	0.69934714092751	0.781946234511333	0.999999999993352
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/2221	12/18639	0.0833333333333333	0.69934714092751	0.781946234511333	0.999999999993352
GO:0003720	telomerase activity	1/2221	12/18639	0.0833333333333333	0.69934714092751	0.781946234511333	0.999999999993352
GO:0004000	adenosine deaminase activity	1/2221	12/18639	0.0833333333333333	0.69934714092751	0.781946234511333	0.999999999993352
GO:0005165	neurotrophin receptor binding	1/2221	12/18639	0.0833333333333333	0.69934714092751	0.781946234511333	0.999999999993352
GO:0005247	voltage-gated chloride channel activity	1/2221	12/18639	0.0833333333333333	0.69934714092751	0.781946234511333	0.999999999993352
GO:0005527	macrolide binding	1/2221	12/18639	0.0833333333333333	0.69934714092751	0.781946234511333	0.999999999993352
GO:0015166	polyol transmembrane transporter activity	1/2221	12/18639	0.0833333333333333	0.69934714092751	0.781946234511333	0.999999999993352
GO:0015368	calcium:monoatomic cation antiporter activity	1/2221	12/18639	0.0833333333333333	0.69934714092751	0.781946234511333	0.999999999993352
GO:0017166	vinculin binding	1/2221	12/18639	0.0833333333333333	0.69934714092751	0.781946234511333	0.999999999993352
GO:0034452	dynactin binding	1/2221	12/18639	0.0833333333333333	0.69934714092751	0.781946234511333	0.999999999993352
GO:0035259	nuclear glucocorticoid receptor binding	1/2221	12/18639	0.0833333333333333	0.69934714092751	0.781946234511333	0.999999999993352
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/2221	12/18639	0.0833333333333333	0.69934714092751	0.781946234511333	0.999999999993352
GO:0140900	chloride:bicarbonate antiporter activity	1/2221	12/18639	0.0833333333333333	0.69934714092751	0.781946234511333	0.999999999993352
GO:1990459	transferrin receptor binding	1/2221	12/18639	0.0833333333333333	0.69934714092751	0.781946234511333	0.999999999993352
GO:1902936	phosphatidylinositol bisphosphate binding	11/2221	111/18639	0.0990990990990991	0.831656059481363	0.784675033695347	0.999999999993352
GO:0008175	tRNA methyltransferase activity	3/2221	34/18639	0.0882352941176471	0.740485208040893	0.787942063040279	0.999999999993352
GO:0004536	DNA nuclease activity	6/2221	64/18639	0.09375	0.786765533543449	0.789879633135333	0.999999999993352
GO:0005540	hyaluronic acid binding	2/2221	24/18639	0.0833333333333333	0.69934714092751	0.798076057560711	0.999999999993352
GO:0015149	hexose transmembrane transporter activity	2/2221	24/18639	0.0833333333333333	0.69934714092751	0.798076057560711	0.999999999993352
GO:0019957	C-C chemokine binding	2/2221	24/18639	0.0833333333333333	0.69934714092751	0.798076057560711	0.999999999993352
GO:0030215	semaphorin receptor binding	2/2221	24/18639	0.0833333333333333	0.69934714092751	0.798076057560711	0.999999999993352
GO:0050431	transforming growth factor beta binding	2/2221	24/18639	0.0833333333333333	0.69934714092751	0.798076057560711	0.999999999993352
GO:0055056	D-glucose transmembrane transporter activity	2/2221	24/18639	0.0833333333333333	0.69934714092751	0.798076057560711	0.999999999993352
GO:0070840	dynein complex binding	2/2221	24/18639	0.0833333333333333	0.69934714092751	0.798076057560711	0.999999999993352
GO:0140033	acetylation-dependent protein binding	2/2221	24/18639	0.0833333333333333	0.69934714092751	0.798076057560711	0.999999999993352
GO:0003964	RNA-directed DNA polymerase activity	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0005172	vascular endothelial growth factor receptor binding	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0005542	folic acid binding	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0019104	DNA N-glycosylase activity	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0031432	titin binding	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0031994	insulin-like growth factor I binding	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0032396	inhibitory MHC class I receptor activity	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0035673	oligopeptide transmembrane transporter activity	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0046974	histone H3K9 methyltransferase activity	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0046975	histone H3K36 methyltransferase activity	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0061459	L-arginine transmembrane transporter activity	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0071837	HMG box domain binding	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/2221	13/18639	0.0769230769230769	0.645551207010009	0.807945988263968	0.999999999993352
GO:0005251	delayed rectifier potassium channel activity	2/2221	25/18639	0.08	0.67137325529041	0.816492723224585	0.999999999993352
GO:0015645	fatty acid ligase activity	2/2221	25/18639	0.08	0.67137325529041	0.816492723224585	0.999999999993352
GO:0015662	P-type ion transporter activity	2/2221	25/18639	0.08	0.67137325529041	0.816492723224585	0.999999999993352
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	2/2221	25/18639	0.08	0.67137325529041	0.816492723224585	0.999999999993352
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/2221	25/18639	0.08	0.67137325529041	0.816492723224585	0.999999999993352
GO:0019707	protein-cysteine S-acyltransferase activity	2/2221	25/18639	0.08	0.67137325529041	0.816492723224585	0.999999999993352
GO:0042974	nuclear retinoic acid receptor binding	2/2221	25/18639	0.08	0.67137325529041	0.816492723224585	0.999999999993352
GO:0120515	fatty acid-CoA ligase activity	2/2221	25/18639	0.08	0.67137325529041	0.816492723224585	0.999999999993352
GO:0140358	P-type transmembrane transporter activity	2/2221	25/18639	0.08	0.67137325529041	0.816492723224585	0.999999999993352
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	8/2221	86/18639	0.0930232558139535	0.780666575919081	0.818904768337567	0.999999999993352
GO:0050660	flavin adenine dinucleotide binding	8/2221	86/18639	0.0930232558139535	0.780666575919081	0.818904768337567	0.999999999993352
GO:0008173	RNA methyltransferase activity	6/2221	67/18639	0.0895522388059701	0.751537226071354	0.824961162897543	0.999999999993352
GO:0050840	extracellular matrix binding	6/2221	67/18639	0.0895522388059701	0.751537226071354	0.824961162897543	0.999999999993352
GO:0015932	nucleobase-containing compound transmembrane transporter activity	5/2221	57/18639	0.087719298245614	0.736154885186853	0.824971140792833	0.999999999993352
GO:0008013	beta-catenin binding	10/2221	106/18639	0.0943396226415094	0.791713744446238	0.825963286593899	0.999999999993352
GO:0061749	forked DNA-dependent helicase activity	4/2221	47/18639	0.0851063829787234	0.714226867330223	0.82732449309126	0.999999999993352
GO:1990518	single-stranded 3'-5' DNA helicase activity	4/2221	47/18639	0.0851063829787234	0.714226867330223	0.82732449309126	0.999999999993352
GO:0008174	mRNA methyltransferase activity	1/2221	14/18639	0.0714285714285714	0.599440406509294	0.830846877347278	0.999999999993352
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/2221	14/18639	0.0714285714285714	0.599440406509294	0.830846877347278	0.999999999993352
GO:0031404	chloride ion binding	1/2221	14/18639	0.0714285714285714	0.599440406509294	0.830846877347278	0.999999999993352
GO:0042043	neurexin family protein binding	1/2221	14/18639	0.0714285714285714	0.599440406509294	0.830846877347278	0.999999999993352
GO:0044548	S100 protein binding	1/2221	14/18639	0.0714285714285714	0.599440406509294	0.830846877347278	0.999999999993352
GO:0061783	peptidoglycan muralytic activity	1/2221	14/18639	0.0714285714285714	0.599440406509294	0.830846877347278	0.999999999993352
GO:0004529	DNA exonuclease activity	2/2221	26/18639	0.0769230769230769	0.645551207010009	0.833389796303496	0.999999999993352
GO:0005160	transforming growth factor beta receptor binding	2/2221	26/18639	0.0769230769230769	0.645551207010009	0.833389796303496	0.999999999993352
GO:0015145	monosaccharide transmembrane transporter activity	2/2221	26/18639	0.0769230769230769	0.645551207010009	0.833389796303496	0.999999999993352
GO:0030507	spectrin binding	2/2221	26/18639	0.0769230769230769	0.645551207010009	0.833389796303496	0.999999999993352
GO:0034237	protein kinase A regulatory subunit binding	2/2221	26/18639	0.0769230769230769	0.645551207010009	0.833389796303496	0.999999999993352
GO:0140030	modification-dependent protein binding	17/2221	173/18639	0.0982658959537572	0.824663680631284	0.833821081496643	0.999999999993352
GO:0030280	structural constituent of skin epidermis	3/2221	37/18639	0.0810810810810811	0.680445866848388	0.833883779614152	0.999999999993352
GO:0009378	four-way junction helicase activity	4/2221	48/18639	0.0833333333333333	0.69934714092751	0.839627244596284	0.999999999993352
GO:0036121	double-stranded DNA helicase activity	4/2221	48/18639	0.0833333333333333	0.69934714092751	0.839627244596284	0.999999999993352
GO:0043138	3'-5' DNA helicase activity	4/2221	48/18639	0.0833333333333333	0.69934714092751	0.839627244596284	0.999999999993352
GO:0140693	molecular condensate scaffold activity	4/2221	48/18639	0.0833333333333333	0.69934714092751	0.839627244596284	0.999999999993352
GO:0036002	pre-mRNA binding	5/2221	59/18639	0.0847457627118644	0.711200482299163	0.84715612001376	0.999999999993352
GO:0070888	E-box binding	5/2221	59/18639	0.0847457627118644	0.711200482299163	0.84715612001376	0.999999999993352
GO:0016405	CoA-ligase activity	2/2221	27/18639	0.0740740740740741	0.621641903046676	0.848867744011974	0.999999999993352
GO:0035255	ionotropic glutamate receptor binding	2/2221	27/18639	0.0740740740740741	0.621641903046676	0.848867744011974	0.999999999993352
GO:0000774	adenyl-nucleotide exchange factor activity	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0005523	tropomyosin binding	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0008242	omega peptidase activity	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0015250	water channel activity	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0015929	hexosaminidase activity	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0030553	cGMP binding	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0031005	filamin binding	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0034483	heparan sulfate sulfotransferase activity	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0042809	nuclear vitamin D receptor binding	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0047372	monoacylglycerol lipase activity	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0048531	beta-1,3-galactosyltransferase activity	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0050780	dopamine receptor binding	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0051371	muscle alpha-actinin binding	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0140161	monocarboxylate:sodium symporter activity	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0140776	protein-containing complex destabilizing activity	1/2221	15/18639	0.0666666666666667	0.559477712742008	0.851018103409651	0.999999999993352
GO:0048020	CCR chemokine receptor binding	4/2221	50/18639	0.08	0.67137325529041	0.862028769297643	0.999999999993352
GO:0016866	intramolecular transferase activity	2/2221	28/18639	0.0714285714285714	0.599440406509294	0.863024677324636	0.999999999993352
GO:0051119	sugar transmembrane transporter activity	2/2221	28/18639	0.0714285714285714	0.599440406509294	0.863024677324636	0.999999999993352
GO:0140299	molecular sensor activity	6/2221	71/18639	0.0845070422535211	0.709197100658884	0.864289676483565	0.999999999993352
GO:0140597	protein carrier chaperone	18/2221	188/18639	0.0957446808510638	0.803505225746501	0.868133654459002	0.999999999993352
GO:0008142	oxysterol binding	1/2221	16/18639	0.0625	0.524510355695633	0.86878489853031	0.999999999993352
GO:0016722	oxidoreductase activity, acting on metal ions	1/2221	16/18639	0.0625	0.524510355695633	0.86878489853031	0.999999999993352
GO:0022858	alanine transmembrane transporter activity	1/2221	16/18639	0.0625	0.524510355695633	0.86878489853031	0.999999999993352
GO:0071949	FAD binding	3/2221	40/18639	0.075	0.629412426834759	0.870982602161111	0.999999999993352
GO:0016597	amino acid binding	4/2221	51/18639	0.0784313725490196	0.658209073814127	0.87218863544275	0.999999999993352
GO:0005200	structural constituent of cytoskeleton	10/2221	112/18639	0.0892857142857143	0.749300508136618	0.872557145805745	0.999999999993352
GO:0004181	metallocarboxypeptidase activity	2/2221	29/18639	0.0689655172413793	0.578770047664146	0.875955486113769	0.999999999993352
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	2/2221	29/18639	0.0689655172413793	0.578770047664146	0.875955486113769	0.999999999993352
GO:0016417	S-acyltransferase activity	2/2221	29/18639	0.0689655172413793	0.578770047664146	0.875955486113769	0.999999999993352
GO:0097472	cyclin-dependent protein kinase activity	2/2221	29/18639	0.0689655172413793	0.578770047664146	0.875955486113769	0.999999999993352
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	4/2221	52/18639	0.0769230769230769	0.645551207010009	0.881695985168534	0.999999999993352
GO:0005126	cytokine receptor binding	27/2221	275/18639	0.0981818181818182	0.82395808603823	0.882212464781619	0.999999999993352
GO:0004550	nucleoside diphosphate kinase activity	1/2221	17/18639	0.0588235294117647	0.493656805360595	0.88443375963562	0.999999999993352
GO:0009881	photoreceptor activity	1/2221	17/18639	0.0588235294117647	0.493656805360595	0.88443375963562	0.999999999993352
GO:0015278	intracellularly gated calcium channel activity	1/2221	17/18639	0.0588235294117647	0.493656805360595	0.88443375963562	0.999999999993352
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/2221	17/18639	0.0588235294117647	0.493656805360595	0.88443375963562	0.999999999993352
GO:0036041	long-chain fatty acid binding	1/2221	17/18639	0.0588235294117647	0.493656805360595	0.88443375963562	0.999999999993352
GO:0045236	CXCR chemokine receptor binding	1/2221	17/18639	0.0588235294117647	0.493656805360595	0.88443375963562	0.999999999993352
GO:0070492	oligosaccharide binding	1/2221	17/18639	0.0588235294117647	0.493656805360595	0.88443375963562	0.999999999993352
GO:1990226	histone methyltransferase binding	1/2221	17/18639	0.0588235294117647	0.493656805360595	0.88443375963562	0.999999999993352
GO:0031210	phosphatidylcholine binding	2/2221	30/18639	0.0666666666666667	0.559477712742008	0.887751213677707	0.999999999993352
GO:0048019	receptor antagonist activity	2/2221	30/18639	0.0666666666666667	0.559477712742008	0.887751213677707	0.999999999993352
GO:0035064	methylated histone binding	6/2221	74/18639	0.0810810810810811	0.680445866848388	0.88872368195146	0.999999999993352
GO:0005506	iron ion binding	14/2221	154/18639	0.0909090909090909	0.762924153739102	0.890627945884601	0.999999999993352
GO:0001221	transcription coregulator binding	10/2221	115/18639	0.0869565217391304	0.729753538359141	0.891765179122589	0.999999999993352
GO:0015291	secondary active transmembrane transporter activity	28/2221	287/18639	0.0975609756097561	0.818747872305378	0.89318843960747	0.999999999993352
GO:0001664	G protein-coupled receptor binding	29/2221	297/18639	0.0976430976430976	0.819437054016072	0.895856689393214	0.999999999993352
GO:0061135	endopeptidase regulator activity	17/2221	184/18639	0.0923913043478261	0.775363134506587	0.896077232369277	0.999999999993352
GO:0005372	water transmembrane transporter activity	1/2221	18/18639	0.0555555555555556	0.466231427285007	0.898217060024906	0.999999999993352
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/2221	18/18639	0.0555555555555556	0.466231427285007	0.898217060024906	0.999999999993352
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/2221	18/18639	0.0555555555555556	0.466231427285007	0.898217060024906	0.999999999993352
GO:0017128	phospholipid scramblase activity	1/2221	18/18639	0.0555555555555556	0.466231427285007	0.898217060024906	0.999999999993352
GO:0034185	apolipoprotein binding	1/2221	18/18639	0.0555555555555556	0.466231427285007	0.898217060024906	0.999999999993352
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/2221	31/18639	0.0645161290322581	0.54143004458904	0.898498625929452	0.999999999993352
GO:0016411	acylglycerol O-acyltransferase activity	2/2221	31/18639	0.0645161290322581	0.54143004458904	0.898498625929452	0.999999999993352
GO:0072349	modified amino acid transmembrane transporter activity	2/2221	31/18639	0.0645161290322581	0.54143004458904	0.898498625929452	0.999999999993352
GO:0004896	cytokine receptor activity	8/2221	96/18639	0.0833333333333333	0.69934714092751	0.898512150670647	0.999999999993352
GO:0019838	growth factor binding	12/2221	136/18639	0.0882352941176471	0.740485208040893	0.898626922584073	0.999999999993352
GO:0005245	voltage-gated calcium channel activity	3/2221	43/18639	0.0697674418604651	0.585499931939311	0.900555065385177	0.999999999993352
GO:0140034	methylation-dependent protein binding	6/2221	76/18639	0.0789473684210526	0.662539396668168	0.902849876965228	0.999999999993352
GO:0003730	mRNA 3'-UTR binding	25/2221	262/18639	0.0954198473282443	0.800779169000966	0.904748953213349	0.999999999993352
GO:0008378	galactosyltransferase activity	2/2221	32/18639	0.0625	0.524510355695633	0.908279937768821	0.999999999993352
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/2221	32/18639	0.0625	0.524510355695633	0.908279937768821	0.999999999993352
GO:0071813	lipoprotein particle binding	2/2221	32/18639	0.0625	0.524510355695633	0.908279937768821	0.999999999993352
GO:0071814	protein-lipid complex binding	2/2221	32/18639	0.0625	0.524510355695633	0.908279937768821	0.999999999993352
GO:0001223	transcription coactivator binding	3/2221	44/18639	0.0681818181818182	0.572193115304326	0.908961902047843	0.999999999993352
GO:0030547	signaling receptor inhibitor activity	3/2221	44/18639	0.0681818181818182	0.572193115304326	0.908961902047843	0.999999999993352
GO:0005229	intracellularly calcium-gated chloride channel activity	1/2221	19/18639	0.0526315789473684	0.441692931112112	0.910357112099697	0.999999999993352
GO:0005520	insulin-like growth factor binding	1/2221	19/18639	0.0526315789473684	0.441692931112112	0.910357112099697	0.999999999993352
GO:0008381	mechanosensitive monoatomic ion channel activity	1/2221	19/18639	0.0526315789473684	0.441692931112112	0.910357112099697	0.999999999993352
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/2221	19/18639	0.0526315789473684	0.441692931112112	0.910357112099697	0.999999999993352
GO:0042834	peptidoglycan binding	1/2221	19/18639	0.0526315789473684	0.441692931112112	0.910357112099697	0.999999999993352
GO:0141147	intracellularly calcium-gated channel activity	1/2221	19/18639	0.0526315789473684	0.441692931112112	0.910357112099697	0.999999999993352
GO:0016758	hexosyltransferase activity	18/2221	197/18639	0.0913705583756345	0.766796865179402	0.910776817062529	0.999999999993352
GO:0042054	histone methyltransferase activity	5/2221	67/18639	0.0746268656716418	0.626281021726128	0.913818374984096	0.999999999993352
GO:0008009	chemokine activity	3/2221	45/18639	0.0666666666666667	0.559477712742008	0.916718551450623	0.999999999993352
GO:0046915	transition metal ion transmembrane transporter activity	3/2221	45/18639	0.0666666666666667	0.559477712742008	0.916718551450623	0.999999999993352
GO:1901681	sulfur compound binding	26/2221	275/18639	0.0945454545454545	0.793441119888666	0.917159428499262	0.999999999993352
GO:0010851	cyclase regulator activity	1/2221	20/18639	0.05	0.419608284556506	0.921049746580179	0.999999999993352
GO:0015095	magnesium ion transmembrane transporter activity	1/2221	20/18639	0.05	0.419608284556506	0.921049746580179	0.999999999993352
GO:0030627	pre-mRNA 5'-splice site binding	1/2221	20/18639	0.05	0.419608284556506	0.921049746580179	0.999999999993352
GO:0140664	ATP-dependent DNA damage sensor activity	1/2221	20/18639	0.05	0.419608284556506	0.921049746580179	0.999999999993352
GO:0140939	histone H4 methyltransferase activity	1/2221	20/18639	0.05	0.419608284556506	0.921049746580179	0.999999999993352
GO:0008376	acetylgalactosaminyltransferase activity	2/2221	34/18639	0.0588235294117647	0.493656805360595	0.925249577965551	0.999999999993352
GO:0002039	p53 binding	5/2221	69/18639	0.072463768115942	0.608127948632618	0.925840528602217	0.999999999993352
GO:0016279	protein-lysine N-methyltransferase activity	5/2221	69/18639	0.072463768115942	0.608127948632618	0.925840528602217	0.999999999993352
GO:0046906	tetrapyrrole binding	13/2221	152/18639	0.0855263157894737	0.717751013057181	0.926379595169116	0.999999999993352
GO:0020037	heme binding	12/2221	142/18639	0.0845070422535211	0.709197100658884	0.926400202844109	0.999999999993352
GO:0048306	calcium-dependent protein binding	6/2221	80/18639	0.075	0.629412426834759	0.926520451510297	0.999999999993352
GO:0017116	single-stranded DNA helicase activity	4/2221	58/18639	0.0689655172413793	0.578770047664146	0.92675848628743	0.999999999993352
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	7/2221	91/18639	0.0769230769230769	0.645551207010009	0.928146446306753	0.999999999993352
GO:0043495	protein-membrane adaptor activity	3/2221	47/18639	0.0638297872340425	0.535670150497667	0.930450172072958	0.999999999993352
GO:0005123	death receptor binding	1/2221	21/18639	0.0476190476190476	0.399626937672863	0.930467465729726	0.999999999993352
GO:0015125	bile acid transmembrane transporter activity	1/2221	21/18639	0.0476190476190476	0.399626937672863	0.930467465729726	0.999999999993352
GO:0015174	basic amino acid transmembrane transporter activity	1/2221	21/18639	0.0476190476190476	0.399626937672863	0.930467465729726	0.999999999993352
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/2221	21/18639	0.0476190476190476	0.399626937672863	0.930467465729726	0.999999999993352
GO:0051428	peptide hormone receptor binding	1/2221	21/18639	0.0476190476190476	0.399626937672863	0.930467465729726	0.999999999993352
GO:0070182	DNA polymerase binding	1/2221	21/18639	0.0476190476190476	0.399626937672863	0.930467465729726	0.999999999993352
GO:0016278	lysine N-methyltransferase activity	5/2221	70/18639	0.0714285714285714	0.599440406509294	0.931273439541316	0.999999999993352
GO:0004879	nuclear receptor activity	4/2221	59/18639	0.0677966101694915	0.56896038583933	0.932547749289151	0.999999999993352
GO:0005343	organic acid:sodium symporter activity	2/2221	35/18639	0.0571428571428571	0.479552325207435	0.93257872845317	0.999999999993352
GO:0016229	steroid dehydrogenase activity	2/2221	35/18639	0.0571428571428571	0.479552325207435	0.93257872845317	0.999999999993352
GO:0098531	ligand-modulated transcription factor activity	4/2221	60/18639	0.0666666666666667	0.559477712742008	0.937919359429983	0.999999999993352
GO:0015377	chloride:monoatomic cation symporter activity	1/2221	22/18639	0.0454545454545455	0.381462076869551	0.938762221268145	0.999999999993352
GO:0016409	palmitoyltransferase activity	2/2221	36/18639	0.0555555555555556	0.466231427285007	0.939223543255627	0.999999999993352
GO:0045505	dynein intermediate chain binding	2/2221	36/18639	0.0555555555555556	0.466231427285007	0.939223543255627	0.999999999993352
GO:0005516	calmodulin binding	18/2221	207/18639	0.0869565217391304	0.729753538359141	0.944165110763594	0.999999999993352
GO:0022829	wide pore channel activity	2/2221	37/18639	0.0540540540540541	0.453630577898926	0.945242958320854	0.999999999993352
GO:0043539	protein serine/threonine kinase activator activity	5/2221	73/18639	0.0684931506849315	0.574805869255488	0.945499492009433	0.999999999993352
GO:0005283	amino acid:sodium symporter activity	1/2221	23/18639	0.0434782608695652	0.36487676917957	0.946067861627142	0.999999999993352
GO:0016493	C-C chemokine receptor activity	1/2221	23/18639	0.0434782608695652	0.36487676917957	0.946067861627142	0.999999999993352
GO:0140103	catalytic activity, acting on a glycoprotein	1/2221	23/18639	0.0434782608695652	0.36487676917957	0.946067861627142	0.999999999993352
GO:0003678	DNA helicase activity	5/2221	74/18639	0.0675675675675676	0.567038222373657	0.949613681144069	0.999999999993352
GO:0042887	amide transmembrane transporter activity	2/2221	38/18639	0.0526315789473684	0.441692931112112	0.950691588171742	0.999999999993352
GO:0140612	DNA damage sensor activity	1/2221	24/18639	0.0416666666666667	0.349673570463755	0.9525022878909	0.999999999993352
GO:0005178	integrin binding	13/2221	161/18639	0.0807453416149068	0.677628285619202	0.955090426291726	0.999999999993352
GO:0005262	calcium channel activity	10/2221	131/18639	0.0763358778625954	0.640623335200773	0.958066996580885	0.999999999993352
GO:0003707	nuclear steroid receptor activity	1/2221	25/18639	0.04	0.335686627645205	0.95816935308533	0.999999999993352
GO:0015271	outward rectifier potassium channel activity	1/2221	25/18639	0.04	0.335686627645205	0.95816935308533	0.999999999993352
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/2221	25/18639	0.04	0.335686627645205	0.95816935308533	0.999999999993352
GO:0017056	structural constituent of nuclear pore	1/2221	25/18639	0.04	0.335686627645205	0.95816935308533	0.999999999993352
GO:0071855	neuropeptide receptor binding	2/2221	40/18639	0.05	0.419608284556506	0.960074514066388	0.999999999993352
GO:0001637	G protein-coupled chemoattractant receptor activity	1/2221	26/18639	0.0384615384615385	0.322775603505005	0.963160535356603	0.999999999993352
GO:0004950	chemokine receptor activity	1/2221	26/18639	0.0384615384615385	0.322775603505005	0.963160535356603	0.999999999993352
GO:0005227	calcium-activated cation channel activity	1/2221	26/18639	0.0384615384615385	0.322775603505005	0.963160535356603	0.999999999993352
GO:0030247	polysaccharide binding	1/2221	26/18639	0.0384615384615385	0.322775603505005	0.963160535356603	0.999999999993352
GO:0015175	neutral L-amino acid transmembrane transporter activity	2/2221	41/18639	0.0487804878048781	0.409373936152689	0.964098236094477	0.999999999993352
GO:0098632	cell-cell adhesion mediator activity	3/2221	55/18639	0.0545454545454545	0.457754492243461	0.966990407317357	0.999999999993352
GO:0005104	fibroblast growth factor receptor binding	1/2221	27/18639	0.037037037037037	0.310820951523338	0.967556411946781	0.999999999993352
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/2221	27/18639	0.037037037037037	0.310820951523338	0.967556411946781	0.999999999993352
GO:0008307	structural constituent of muscle	2/2221	42/18639	0.0476190476190476	0.399626937672863	0.967730463036918	0.999999999993352
GO:0042056	chemoattractant activity	2/2221	42/18639	0.0476190476190476	0.399626937672863	0.967730463036918	0.999999999993352
GO:0005253	monoatomic anion channel activity	7/2221	103/18639	0.0679611650485437	0.57034135764962	0.969182634553696	0.999999999993352
GO:0015085	calcium ion transmembrane transporter activity	11/2221	147/18639	0.0748299319727891	0.627985187771642	0.970192825989642	0.999999999993352
GO:0005242	inward rectifier potassium channel activity	1/2221	28/18639	0.0357142857142857	0.299720203254647	0.971427957673527	0.999999999993352
GO:0051393	alpha-actinin binding	1/2221	28/18639	0.0357142857142857	0.299720203254647	0.971427957673527	0.999999999993352
GO:0030414	peptidase inhibitor activity	13/2221	169/18639	0.0769230769230769	0.645551207010009	0.97182543654151	0.999999999993352
GO:0015294	solute:monoatomic cation symporter activity	8/2221	116/18639	0.0689655172413793	0.578770047664146	0.973060379729768	0.999999999993352
GO:0030020	extracellular matrix structural constituent conferring tensile strength	2/2221	44/18639	0.0454545454545455	0.381462076869551	0.973961855019762	0.999999999993352
GO:0005416	amino acid:monoatomic cation symporter activity	1/2221	29/18639	0.0344827586206897	0.289385023832073	0.974837688800662	0.999999999993352
GO:0035250	UDP-galactosyltransferase activity	1/2221	29/18639	0.0344827586206897	0.289385023832073	0.974837688800662	0.999999999993352
GO:0099604	ligand-gated calcium channel activity	1/2221	29/18639	0.0344827586206897	0.289385023832073	0.974837688800662	0.999999999993352
GO:0004866	endopeptidase inhibitor activity	12/2221	161/18639	0.0745341614906832	0.625503032879264	0.975882678235702	0.999999999993352
GO:0005125	cytokine activity	19/2221	234/18639	0.0811965811965812	0.68141516295501	0.976467180736345	0.999999999993352
GO:0042605	peptide antigen binding	2/2221	45/18639	0.0444444444444444	0.372985141828005	0.976624334255536	0.999999999993352
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/2221	30/18639	0.0333333333333333	0.279738856371004	0.977840670701453	0.999999999993352
GO:0022839	monoatomic ion-gated channel activity	1/2221	30/18639	0.0333333333333333	0.279738856371004	0.977840670701453	0.999999999993352
GO:0004175	endopeptidase activity	36/2221	405/18639	0.0888888888888889	0.745970283656011	0.979435186786478	0.999999999993352
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	22/2221	268/18639	0.082089552238806	0.688909123898741	0.980505881209402	0.999999999993352
GO:0099095	ligand-gated monoatomic anion channel activity	2/2221	47/18639	0.0425531914893617	0.357113433665112	0.981181127988425	0.999999999993352
GO:0008528	G protein-coupled peptide receptor activity	8/2221	122/18639	0.0655737704918033	0.550305946959352	0.982553811323586	0.999999999993352
GO:0042910	xenobiotic transmembrane transporter activity	1/2221	32/18639	0.03125	0.262255177847816	0.982814614164553	0.999999999993352
GO:0008188	neuropeptide receptor activity	2/2221	48/18639	0.0416666666666667	0.349673570463755	0.983123566861629	0.999999999993352
GO:0008194	UDP-glycosyltransferase activity	10/2221	145/18639	0.0689655172413793	0.578770047664146	0.983337094675123	0.999999999993352
GO:0015293	symporter activity	10/2221	146/18639	0.0684931506849315	0.574805869255488	0.984445900002274	0.999999999993352
GO:0098631	cell adhesion mediator activity	4/2221	76/18639	0.0526315789473684	0.441692931112112	0.98473764859678	0.999999999993352
GO:0042923	neuropeptide binding	1/2221	33/18639	0.0303030303030303	0.254308051246367	0.984865925065855	0.999999999993352
GO:0140416	transcription regulator inhibitor activity	1/2221	33/18639	0.0303030303030303	0.254308051246367	0.984865925065855	0.999999999993352
GO:0005004	GPI-linked ephrin receptor activity	2/2221	49/18639	0.0408163265306122	0.342537375148168	0.984870554071341	0.999999999993352
GO:0005008	hepatocyte growth factor receptor activity	2/2221	49/18639	0.0408163265306122	0.342537375148168	0.984870554071341	0.999999999993352
GO:0005009	insulin receptor activity	2/2221	49/18639	0.0408163265306122	0.342537375148168	0.984870554071341	0.999999999993352
GO:0005011	macrophage colony-stimulating factor receptor activity	2/2221	49/18639	0.0408163265306122	0.342537375148168	0.984870554071341	0.999999999993352
GO:0005018	platelet-derived growth factor alpha-receptor activity	2/2221	49/18639	0.0408163265306122	0.342537375148168	0.984870554071341	0.999999999993352
GO:0005020	stem cell factor receptor activity	2/2221	49/18639	0.0408163265306122	0.342537375148168	0.984870554071341	0.999999999993352
GO:0008288	boss receptor activity	2/2221	49/18639	0.0408163265306122	0.342537375148168	0.984870554071341	0.999999999993352
GO:0036332	placental growth factor receptor activity	2/2221	49/18639	0.0408163265306122	0.342537375148168	0.984870554071341	0.999999999993352
GO:0038062	protein tyrosine kinase collagen receptor activity	2/2221	49/18639	0.0408163265306122	0.342537375148168	0.984870554071341	0.999999999993352
GO:0060175	brain-derived neurotrophic factor receptor activity	2/2221	49/18639	0.0408163265306122	0.342537375148168	0.984870554071341	0.999999999993352
GO:0003779	actin binding	39/2221	443/18639	0.0880361173814898	0.738813683869243	0.98586105932824	0.999999999993352
GO:0005006	epidermal growth factor receptor activity	2/2221	50/18639	0.04	0.335686627645205	0.98644106291671	0.999999999993352
GO:0005007	fibroblast growth factor receptor activity	2/2221	50/18639	0.04	0.335686627645205	0.98644106291671	0.999999999993352
GO:0005017	platelet-derived growth factor receptor activity	2/2221	50/18639	0.04	0.335686627645205	0.98644106291671	0.999999999993352
GO:0005019	platelet-derived growth factor beta-receptor activity	2/2221	50/18639	0.04	0.335686627645205	0.98644106291671	0.999999999993352
GO:0015171	amino acid transmembrane transporter activity	6/2221	102/18639	0.0588235294117647	0.493656805360595	0.986454172514917	0.999999999993352
GO:0015020	glucuronosyltransferase activity	1/2221	34/18639	0.0294117647058824	0.246828402680298	0.986672481038592	0.999999999993352
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/2221	34/18639	0.0294117647058824	0.246828402680298	0.986672481038592	0.999999999993352
GO:0051427	hormone receptor binding	1/2221	34/18639	0.0294117647058824	0.246828402680298	0.986672481038592	0.999999999993352
GO:0140097	catalytic activity, acting on DNA	28/2221	336/18639	0.0833333333333333	0.69934714092751	0.986724576106417	0.999999999993352
GO:0003689	DNA clamp loader activity	11/2221	160/18639	0.06875	0.576961391265196	0.987291097792541	0.999999999993352
GO:0019199	transmembrane receptor protein kinase activity	4/2221	78/18639	0.0512820512820513	0.430367471340006	0.987301652755823	0.999999999993352
GO:0008509	monoatomic anion transmembrane transporter activity	10/2221	149/18639	0.0671140939597315	0.563232596720142	0.987376656116619	0.999999999993352
GO:0005010	insulin-like growth factor receptor activity	2/2221	51/18639	0.0392156862745098	0.329104536907064	0.98785232269173	0.999999999993352
GO:0005021	vascular endothelial growth factor receptor activity	2/2221	51/18639	0.0392156862745098	0.329104536907064	0.98785232269173	0.999999999993352
GO:0005030	neurotrophin receptor activity	2/2221	51/18639	0.0392156862745098	0.329104536907064	0.98785232269173	0.999999999993352
GO:0015370	solute:sodium symporter activity	4/2221	79/18639	0.0506329113924051	0.424919781829373	0.988424378206253	0.999999999993352
GO:0001217	DNA-binding transcription repressor activity	22/2221	278/18639	0.079136690647482	0.664128220161377	0.988460643667543	0.999999999993352
GO:0001653	peptide receptor activity	8/2221	128/18639	0.0625	0.524510355695633	0.988864288857873	0.999999999993352
GO:0008083	growth factor activity	11/2221	162/18639	0.0679012345679012	0.569838411126119	0.988913050384346	0.999999999993352
GO:0000510	H3-H4 histone complex chaperone activity	10/2221	151/18639	0.0662251655629139	0.555772562326498	0.989036457101063	0.999999999993352
GO:0140584	chromatin extrusion motor activity	10/2221	151/18639	0.0662251655629139	0.555772562326498	0.989036457101063	0.999999999993352
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	10/2221	151/18639	0.0662251655629139	0.555772562326498	0.989036457101063	0.999999999993352
GO:0140849	ATP-dependent H2AZ histone chaperone activity	10/2221	151/18639	0.0662251655629139	0.555772562326498	0.989036457101063	0.999999999993352
GO:0015616	DNA translocase activity	10/2221	152/18639	0.0657894736842105	0.55211616389014	0.989787986850536	0.999999999993352
GO:0140674	ATP-dependent histone chaperone activity	10/2221	152/18639	0.0657894736842105	0.55211616389014	0.989787986850536	0.999999999993352
GO:0016500	protein-hormone receptor activity	3/2221	67/18639	0.0447761194029851	0.375768613035677	0.98982337214755	0.999999999993352
GO:0005003	ephrin receptor activity	2/2221	53/18639	0.0377358490566038	0.316685497778495	0.99025815820037	0.999999999993352
GO:0005005	transmembrane-ephrin receptor activity	2/2221	53/18639	0.0377358490566038	0.316685497778495	0.99025815820037	0.999999999993352
GO:0017046	peptide hormone binding	2/2221	53/18639	0.0377358490566038	0.316685497778495	0.99025815820037	0.999999999993352
GO:0038064	collagen receptor activity	2/2221	53/18639	0.0377358490566038	0.316685497778495	0.99025815820037	0.999999999993352
GO:0004497	monooxygenase activity	6/2221	106/18639	0.0566037735849057	0.475028246667743	0.990271133302033	0.999999999993352
GO:0140713	histone chaperone activity	11/2221	164/18639	0.0670731707317073	0.562889162209947	0.990341088712738	0.999999999993352
GO:0015101	organic cation transmembrane transporter activity	4/2221	81/18639	0.0493827160493827	0.41442793536445	0.99039215410169	0.999999999993352
GO:0061775	cohesin loader activity	10/2221	153/18639	0.065359477124183	0.548507561511773	0.990491277700833	0.999999999993352
GO:0003777	microtubule motor activity	3/2221	68/18639	0.0441176470588235	0.370242604020447	0.99079785855816	0.999999999993352
GO:0042805	actinin binding	1/2221	37/18639	0.027027027027027	0.226815288949463	0.990898549530862	0.999999999993352
GO:0004252	serine-type endopeptidase activity	12/2221	176/18639	0.0681818181818182	0.572193115304326	0.990916855369668	0.999999999993352
GO:0017171	serine hydrolase activity	14/2221	198/18639	0.0707070707070707	0.59338545290819	0.990976590192459	0.999999999993352
GO:0008094	ATP-dependent activity, acting on DNA	15/2221	210/18639	0.0714285714285714	0.599440406509294	0.99162817102454	0.999999999993352
GO:0004386	helicase activity	10/2221	155/18639	0.0645161290322581	0.54143004458904	0.991764284250555	0.999999999993352
GO:0000146	microfilament motor activity	1/2221	38/18639	0.0263157894736842	0.220846465556056	0.99198522416219	0.999999999993352
GO:0005109	frizzled binding	1/2221	38/18639	0.0263157894736842	0.220846465556056	0.99198522416219	0.999999999993352
GO:0008028	monocarboxylic acid transmembrane transporter activity	3/2221	70/18639	0.0428571428571429	0.359664243905577	0.992483706494151	0.999999999993352
GO:0004222	metalloendopeptidase activity	6/2221	110/18639	0.0545454545454545	0.457754492243461	0.993054954370311	0.999999999993352
GO:0140658	ATP-dependent chromatin remodeler activity	10/2221	158/18639	0.0632911392405063	0.531149727286717	0.993378019084114	0.999999999993352
GO:0005261	monoatomic cation channel activity	27/2221	341/18639	0.0791788856304985	0.664482327450186	0.993813576746365	0.999999999993352
GO:0008236	serine-type peptidase activity	13/2221	194/18639	0.0670103092783505	0.562361618477792	0.994313522687062	0.999999999993352
GO:0004714	transmembrane receptor protein tyrosine kinase activity	2/2221	60/18639	0.0333333333333333	0.279738856371004	0.995538336859671	0.999999999993352
GO:0051015	actin filament binding	14/2221	209/18639	0.0669856459330144	0.562154639597233	0.995627039641633	0.999999999993352
GO:0015081	sodium ion transmembrane transporter activity	10/2221	164/18639	0.0609756097560976	0.511717420190861	0.995755608122936	0.999999999993352
GO:0003724	RNA helicase activity	3/2221	77/18639	0.038961038961039	0.326967494459615	0.996335652151254	0.999999999993352
GO:1901682	sulfur compound transmembrane transporter activity	2/2221	63/18639	0.0317460317460317	0.266417958448575	0.996818701732443	0.999999999993352
GO:0008186	ATP-dependent activity, acting on RNA	3/2221	79/18639	0.0379746835443038	0.31868983637203	0.99702356346605	0.999999999993352
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/2221	46/18639	0.0217391304347826	0.182438384589785	0.997102499297682	0.999999999993352
GO:0140359	ABC-type transporter activity	1/2221	47/18639	0.0212765957446809	0.178556716832556	0.997448616065275	0.999999999993352
GO:0038024	cargo receptor activity	2/2221	65/18639	0.0307692307692308	0.258220482804004	0.99746360077133	0.999999999993352
GO:0015079	potassium ion transmembrane transporter activity	9/2221	160/18639	0.05625	0.472059320126069	0.997688904232307	0.999999999993352
GO:0005244	voltage-gated monoatomic ion channel activity	10/2221	173/18639	0.0578034682080925	0.485096282724285	0.997865660207168	0.999999999993352
GO:0005254	chloride channel activity	3/2221	83/18639	0.036144578313253	0.303331290040848	0.998042505503586	0.999999999993352
GO:0022832	voltage-gated channel activity	10/2221	175/18639	0.0571428571428571	0.479552325207435	0.998173720414557	0.999999999993352
GO:0016887	ATP hydrolysis activity	32/2221	417/18639	0.0767386091127098	0.644003122580729	0.998320307015163	0.999999999993352
GO:0046943	carboxylic acid transmembrane transporter activity	11/2221	188/18639	0.0585106382978723	0.491030971289528	0.99832317032642	0.999999999993352
GO:0005216	monoatomic ion channel activity	35/2221	448/18639	0.078125	0.655637944619541	0.998324278463397	0.999999999993352
GO:0005342	organic acid transmembrane transporter activity	11/2221	189/18639	0.0582010582010582	0.488432923822388	0.998446651868726	0.999999999993352
GO:0008514	organic anion transmembrane transporter activity	18/2221	269/18639	0.0669144981412639	0.561557555540305	0.998454256650241	0.999999999993352
GO:0015103	inorganic anion transmembrane transporter activity	9/2221	165/18639	0.0545454545454545	0.457754492243461	0.998454492379975	0.999999999993352
GO:0005272	sodium channel activity	1/2221	51/18639	0.0196078431372549	0.164552268453532	0.99846625489103	0.999999999993352
GO:0022843	voltage-gated monoatomic cation channel activity	7/2221	143/18639	0.048951048951049	0.410805313551824	0.998805816445255	0.999999999993352
GO:0170055	lipid transmembrane transporter activity	1/2221	56/18639	0.0178571428571429	0.149860101627324	0.999188284997038	0.999999999993352
GO:0015108	chloride transmembrane transporter activity	5/2221	121/18639	0.0413223140495868	0.346783706245046	0.999224654009259	0.999999999993352
GO:0004867	serine-type endopeptidase inhibitor activity	3/2221	95/18639	0.0315789473684211	0.265015758667267	0.999455688927355	0.999999999993352
GO:0005201	extracellular matrix structural constituent	8/2221	168/18639	0.0476190476190476	0.399626937672863	0.999585899546942	0.999999999993352
GO:0005539	glycosaminoglycan binding	14/2221	242/18639	0.0578512396694215	0.485497188743065	0.999587982747556	0.999999999993352
GO:0005249	voltage-gated potassium channel activity	3/2221	98/18639	0.0306122448979592	0.256903031361126	0.999606590010468	0.999999999993352
GO:0008201	heparin binding	8/2221	172/18639	0.0465116279069767	0.390333287959541	0.999708949538009	0.999999999993352
GO:0005179	hormone activity	5/2221	132/18639	0.0378787878787879	0.317885064057959	0.999735232499615	0.999999999993352
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	35/2221	484/18639	0.0723140495867769	0.606871485928831	0.999770535928004	0.999999999993352
GO:0001216	DNA-binding transcription activator activity	35/2221	491/18639	0.0712830957230143	0.598219550284224	0.999847669123842	0.999999999993352
GO:0005267	potassium channel activity	4/2221	124/18639	0.032258064516129	0.27071502229452	0.99986880177681	0.999999999993352
GO:0046873	metal ion transmembrane transporter activity	29/2221	450/18639	0.0644444444444444	0.540828455650608	0.999967353351832	0.999999999993352
GO:0003823	antigen binding	6/2221	174/18639	0.0344827586206897	0.289385023832073	0.999982650147848	0.999999999993352
GO:0099094	ligand-gated monoatomic cation channel activity	3/2221	136/18639	0.0220588235294118	0.185121302010223	0.999994293991584	0.999999999993352
GO:0030594	neurotransmitter receptor activity	1/2221	97/18639	0.0103092783505155	0.0865171720735064	0.999995631410634	0.999999999993352
GO:0022836	gated channel activity	15/2221	318/18639	0.0471698113207547	0.395856872223119	0.999997548915987	0.999999999993352
GO:0015276	ligand-gated monoatomic ion channel activity	5/2221	186/18639	0.0268817204301075	0.2255958519121	0.999999010366212	0.999999999993352
GO:0045182	translation regulator activity	17/2221	356/18639	0.047752808988764	0.400749485250596	0.999999138525229	0.999999999993352
GO:0022834	ligand-gated channel activity	5/2221	188/18639	0.0265957446808511	0.223195896040695	0.999999201618174	0.999999999993352
GO:0030371	translation repressor activity	7/2221	329/18639	0.0212765957446809	0.178556716832556	0.999999999993352	0.999999999993352