ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005520 insulin-like growth factor binding 7/340 19/18639 0.368421052631579 20.1970588235294 2.6373280619091e-08 1.84876697139828e-05 GO:0031994 insulin-like growth factor I binding 6/340 13/18639 0.461538461538462 25.3018099547511 5.43136399205103e-08 1.90369307921389e-05 GO:0031386 protein tag activity 5/340 15/18639 0.333333333333333 18.2735294117647 5.06757297263431e-06 0.000888092163454163 GO:0141047 molecular tag activity 5/340 15/18639 0.333333333333333 18.2735294117647 5.06757297263431e-06 0.000888092163454163 GO:0048306 calcium-dependent protein binding 9/340 80/18639 0.1125 6.16731617647059 1.49430166405298e-05 0.00209501093300228 GO:0050786 RAGE receptor binding 4/340 11/18639 0.363636363636364 19.9347593582888 3.24409693276214e-05 0.00379018658311044 GO:0030695 GTPase regulator activity 21/340 489/18639 0.0429447852760736 2.35425839047275 0.000271898273684794 0.024484819456101 GO:0060589 nucleoside-triphosphatase regulator activity 21/340 490/18639 0.0428571428571429 2.3494537815126 0.00027942732617519 0.024484819456101 GO:0003925 G protein activity 6/340 54/18639 0.111111111111111 6.09117647058823 0.000435486125001488 0.0339195304028937 GO:0019864 IgG binding 3/340 11/18639 0.272727272727273 14.9510695187166 0.000890400023119559 0.0624170416206811 GO:0005085 guanyl-nucleotide exchange factor activity 12/340 230/18639 0.0521739130434783 2.86020460358056 0.00110266619775083 0.0691640926805421 GO:0019865 immunoglobulin binding 4/340 26/18639 0.153846153846154 8.43393665158371 0.00118397876200643 0.0691640926805421 GO:0031625 ubiquitin protein ligase binding 14/340 302/18639 0.0463576158940397 2.54135177249708 0.0013742717244205 0.0701977238137861 GO:0003735 structural constituent of ribosome 10/340 175/18639 0.0571428571428571 3.13260504201681 0.00143708857409564 0.0701977238137861 GO:0035325 Toll-like receptor binding 3/340 13/18639 0.230769230769231 12.6509049773756 0.00150209109444621 0.0701977238137861 GO:0019763 immunoglobulin receptor activity 3/340 14/18639 0.214285714285714 11.747268907563 0.00188605428583447 0.0826327533981226 GO:0051020 GTPase binding 14/340 315/18639 0.0444444444444444 2.43647058823529 0.00203398979537152 0.0838721674444376 GO:0031267 small GTPase binding 13/340 283/18639 0.0459363957597173 2.51826023695697 0.00218293756893341 0.0850132908790178 GO:0044389 ubiquitin-like protein ligase binding 14/340 322/18639 0.0434782608695652 2.38350383631714 0.00248626210016585 0.091729985906119 GO:0019838 growth factor binding 8/340 136/18639 0.0588235294117647 3.22474048442907 0.00352655370216892 0.120231115922953 GO:0061631 ubiquitin conjugating enzyme activity 4/340 35/18639 0.114285714285714 6.26521008403361 0.00364578573106751 0.120231115922953 GO:0005201 extracellular matrix structural constituent 9/340 168/18639 0.0535714285714286 2.93681722689076 0.00377330178360196 0.120231115922953 GO:0001540 amyloid-beta binding 6/340 83/18639 0.072289156626506 3.96293408929837 0.00409771305232428 0.124891167377362 GO:0005543 phospholipid binding 18/340 497/18639 0.0362173038229376 1.98545389986981 0.00468103021705176 0.127857048306417 GO:0016918 retinal binding 3/340 19/18639 0.157894736842105 8.65588235294118 0.00469321767488418 0.127857048306417 GO:0005501 retinoid binding 4/340 38/18639 0.105263157894737 5.77058823529412 0.00492459387200179 0.127857048306417 GO:0019840 isoprenoid binding 4/340 38/18639 0.105263157894737 5.77058823529412 0.00492459387200179 0.127857048306417 GO:0035091 phosphatidylinositol binding 12/340 284/18639 0.0422535211267606 2.31636288318144 0.00615872600002086 0.151277368075004 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/340 41/18639 0.0975609756097561 5.34835007173601 0.00647406710734682 0.151277368075004 GO:0061650 ubiquitin-like protein conjugating enzyme activity 4/340 41/18639 0.0975609756097561 5.34835007173601 0.00647406710734682 0.151277368075004 GO:1901981 phosphatidylinositol phosphate binding 9/340 185/18639 0.0486486486486487 2.66694753577107 0.0070222826180454 0.152178693896587 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/340 22/18639 0.136363636363636 7.47553475935829 0.00716390427758541 0.152178693896587 GO:0031683 G-protein beta/gamma-subunit complex binding 3/340 22/18639 0.136363636363636 7.47553475935829 0.00716390427758541 0.152178693896587 GO:0050840 extracellular matrix binding 5/340 67/18639 0.0746268656716418 4.09108867427568 0.00752191913270817 0.155084273883189 GO:0030547 signaling receptor inhibitor activity 4/340 44/18639 0.0909090909090909 4.98368983957219 0.00831661665140889 0.166569950646789 GO:0008009 chemokine activity 4/340 45/18639 0.0888888888888889 4.87294117647059 0.00899951917275438 0.175240637225023 GO:0005518 collagen binding 5/340 72/18639 0.0694444444444444 3.80698529411765 0.0101266511078713 0.186810063858362 GO:0042379 chemokine receptor binding 5/340 72/18639 0.0694444444444444 3.80698529411765 0.0101266511078713 0.186810063858362 GO:0005504 fatty acid binding 4/340 47/18639 0.0851063829787234 4.66558197747184 0.0104726739996922 0.188239601891903 GO:0005096 GTPase activator activity 11/340 271/18639 0.040590405904059 2.22518992836987 0.011315894090586 0.196000422956018 GO:0050750 low-density lipoprotein particle receptor binding 3/340 26/18639 0.115384615384615 6.32545248868778 0.0114636481329483 0.196000422956018 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/340 10/18639 0.2 10.9641176470588 0.0135527957086292 0.220942088180211 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 2/340 10/18639 0.2 10.9641176470588 0.0135527957086292 0.220942088180211 GO:0043236 laminin binding 3/340 29/18639 0.103448275862069 5.6710953346856 0.0154780840088464 0.246594020231848 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/340 11/18639 0.181818181818182 9.96737967914438 0.0163666614165203 0.249413688108277 GO:0047676 arachidonate-CoA ligase activity 2/340 11/18639 0.181818181818182 9.96737967914438 0.0163666614165203 0.249413688108277 GO:0001968 fibronectin binding 3/340 30/18639 0.1 5.48205882352941 0.0169701510543901 0.253107997641009 GO:0070325 lipoprotein particle receptor binding 3/340 31/18639 0.0967741935483871 5.30521821631879 0.018539843660282 0.270758966788701 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 2/340 12/18639 0.166666666666667 9.13676470588235 0.0194057511833798 0.277621052643862 GO:0045296 cadherin binding 12/340 334/18639 0.0359281437125748 1.96960197252554 0.0201416492145847 0.282385921988478 GO:0016209 antioxidant activity 5/340 86/18639 0.0581395348837209 3.18724350205198 0.0205467330479257 0.282416860129332 GO:0046030 inositol trisphosphate phosphatase activity 2/340 14/18639 0.142857142857143 7.83151260504202 0.0261234467457748 0.305564810891596 GO:0023023 MHC protein complex binding 3/340 37/18639 0.0810810810810811 4.44491255961844 0.0295949644838017 0.305564810891596 GO:0004467 long-chain fatty acid-CoA ligase activity 2/340 15/18639 0.133333333333333 7.30941176470588 0.0297846068565848 0.305564810891596 GO:0003779 actin binding 14/340 443/18639 0.0316027088036117 1.7324790864427 0.0334528027621018 0.305564810891596 GO:0004708 MAP kinase kinase activity 2/340 16/18639 0.125 6.85257352941176 0.0336360873072861 0.305564810891596 GO:0005521 lamin binding 2/340 16/18639 0.125 6.85257352941176 0.0336360873072861 0.305564810891596 GO:0019841 retinol binding 2/340 16/18639 0.125 6.85257352941176 0.0336360873072861 0.305564810891596 GO:0016874 ligase activity 7/340 167/18639 0.0419161676646707 2.29786896794646 0.0337845896925961 0.305564810891596 GO:0106310 protein serine kinase activity 12/340 361/18639 0.0332409972299169 1.82229102167183 0.0338931144039802 0.305564810891596 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 9/340 243/18639 0.037037037037037 2.03039215686274 0.0347809007301982 0.305564810891596 GO:0004676 3-phosphoinositide-dependent protein kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0004711 ribosomal protein S6 kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0035175 histone H3S10 kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0035979 histone H2AXS139 kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0044022 histone H3S28 kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0044023 histone H4S1 kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0044024 histone H2AS1 kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0044025 histone H2BS14 kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0072354 histone H3T3 kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0072371 histone H2AS121 kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0072518 Rho-dependent protein serine/threonine kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0140823 histone H2BS36 kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0140855 histone H3S57 kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0140995 histone H2A kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0140997 histone H4 kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0140998 histone H2B kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:1990244 histone H2AT120 kinase activity 9/340 245/18639 0.036734693877551 2.0138175270108 0.0363505107060275 0.305564810891596 GO:0004677 DNA-dependent protein kinase activity 9/340 246/18639 0.0365853658536585 2.005631276901 0.0371532539583968 0.305564810891596 GO:0140857 histone H3T45 kinase activity 9/340 246/18639 0.0365853658536585 2.005631276901 0.0371532539583968 0.305564810891596 GO:0016805 dipeptidase activity 2/340 17/18639 0.117647058823529 6.44948096885813 0.0376697701033167 0.305564810891596 GO:0036041 long-chain fatty acid binding 2/340 17/18639 0.117647058823529 6.44948096885813 0.0376697701033167 0.305564810891596 GO:0051787 misfolded protein binding 2/340 17/18639 0.117647058823529 6.44948096885813 0.0376697701033167 0.305564810891596 GO:0070492 oligosaccharide binding 2/340 17/18639 0.117647058823529 6.44948096885813 0.0376697701033167 0.305564810891596 GO:0035402 histone H3T11 kinase activity 9/340 247/18639 0.0364372469635627 1.99751131221719 0.0379680484435057 0.305564810891596 GO:0035403 histone H3T6 kinase activity 9/340 247/18639 0.0364372469635627 1.99751131221719 0.0379680484435057 0.305564810891596 GO:0051015 actin filament binding 8/340 209/18639 0.0382775119617225 2.09839572192513 0.0383405061429953 0.305564810891596 GO:0016877 ligase activity, forming carbon-sulfur bonds 3/340 41/18639 0.0731707317073171 4.01126255380201 0.0385138366996792 0.305564810891596 GO:0004679 AMP-activated protein kinase activity 9/340 248/18639 0.0362903225806452 1.98945683111954 0.0387949617251812 0.305564810891596 GO:0042277 peptide binding 9/340 249/18639 0.036144578313253 1.98146704464918 0.0396340599614178 0.308705289255043 GO:0048487 beta-tubulin binding 3/340 42/18639 0.0714285714285714 3.91575630252101 0.0409337752891288 0.315325016238234 GO:1990381 ubiquitin-specific protease binding 2/340 18/18639 0.111111111111111 6.09117647058823 0.0418777685598621 0.319090388700689 GO:0052745 inositol phosphate phosphatase activity 2/340 20/18639 0.1 5.48205882352941 0.0507862882136582 0.378954015938411 GO:0015631 tubulin binding 12/340 385/18639 0.0311688311688312 1.70869365928189 0.0508552023749057 0.378954015938411 GO:0004180 carboxypeptidase activity 3/340 46/18639 0.0652173913043478 3.5752557544757 0.0513561077234651 0.378954015938411 GO:0004674 protein serine/threonine kinase activity 13/340 433/18639 0.0300230946882217 1.64588371145225 0.055147409813994 0.402690982079269 GO:0033293 monocarboxylic acid binding 4/340 79/18639 0.0506329113924051 2.77572598659717 0.0563775112669822 0.40742923090881 GO:0000287 magnesium ion binding 8/340 230/18639 0.0347826086956522 1.90680306905371 0.0606923650724766 0.431138934180901 GO:0141003 histone H2AX kinase activity 11/340 354/18639 0.0310734463276836 1.70346460618146 0.0608883801482299 0.431138934180901 GO:0048020 CCR chemokine receptor binding 3/340 50/18639 0.06 3.28923529411765 0.0629291974153504 0.434468312788163 GO:0019208 phosphatase regulator activity 5/340 117/18639 0.0427350427350427 2.34276018099548 0.0632179285369367 0.434468312788163 GO:1990782 protein tyrosine kinase binding 5/340 117/18639 0.0427350427350427 2.34276018099548 0.0632179285369367 0.434468312788163 GO:0140996 histone H3 kinase activity 11/340 357/18639 0.030812324929972 1.68914977755808 0.0638457885470341 0.434523279334669 GO:0005212 structural constituent of eye lens 2/340 23/18639 0.0869565217391304 4.76700767263427 0.0652719464895354 0.435502842773793 GO:0031681 G-protein beta-subunit binding 2/340 23/18639 0.0869565217391304 4.76700767263427 0.0652719464895354 0.435502842773793 GO:0140375 immune receptor activity 6/340 156/18639 0.0384615384615385 2.10848416289593 0.0665557675839869 0.435502842773793 GO:0035173 histone kinase activity 11/340 360/18639 0.0305555555555556 1.67507352941176 0.0668955591601562 0.435502842773793 GO:0008017 microtubule binding 9/340 276/18639 0.0326086956521739 1.78762787723785 0.0670960157197855 0.435502842773793 GO:0051082 unfolded protein binding 5/340 121/18639 0.0413223140495868 2.26531356344191 0.0708437688774708 0.452824785271463 GO:0004864 protein phosphatase inhibitor activity 3/340 53/18639 0.0566037735849057 3.10305216426193 0.0723293174045161 0.452824785271463 GO:0005544 calcium-dependent phospholipid binding 3/340 53/18639 0.0566037735849057 3.10305216426193 0.0723293174045161 0.452824785271463 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/340 86/18639 0.0465116279069767 2.54979480164159 0.0723486104855975 0.452824785271463 GO:0015645 fatty acid ligase activity 2/340 25/18639 0.08 4.38564705882353 0.0755981169847916 0.456847241433956 GO:0015662 P-type ion transporter activity 2/340 25/18639 0.08 4.38564705882353 0.0755981169847916 0.456847241433956 GO:0120515 fatty acid-CoA ligase activity 2/340 25/18639 0.08 4.38564705882353 0.0755981169847916 0.456847241433956 GO:0140358 P-type transmembrane transporter activity 2/340 25/18639 0.08 4.38564705882353 0.0755981169847916 0.456847241433956 GO:0140313 molecular sequestering activity 3/340 55/18639 0.0545454545454545 2.99021390374332 0.0789237572821271 0.47286798166471 GO:0004857 enzyme inhibitor activity 12/340 416/18639 0.0288461538461538 1.58136312217195 0.0802733654287305 0.476813461303368 GO:0052742 phosphatidylinositol kinase activity 2/340 26/18639 0.0769230769230769 4.21696832579186 0.0809426560557786 0.476813461303368 GO:0019212 phosphatase inhibitor activity 3/340 56/18639 0.0535714285714286 2.93681722689076 0.0823160088866667 0.480862685246278 GO:0033218 amide binding 8/340 247/18639 0.0323886639676113 1.77556561085973 0.0837770516862005 0.485353001917575 GO:0016405 CoA-ligase activity 2/340 27/18639 0.0740740740740741 4.06078431372549 0.0864000411942935 0.492409990871543 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/340 27/18639 0.0740740740740741 4.06078431372549 0.0864000411942935 0.492409990871543 GO:0035591 signaling adaptor activity 5/340 129/18639 0.0387596899224806 2.12482900136799 0.0875380769175685 0.494872515477544 GO:0046875 ephrin receptor binding 2/340 28/18639 0.0714285714285714 3.91575630252101 0.0919644060221402 0.508548997596851 GO:0050698 proteoglycan sulfotransferase activity 2/340 28/18639 0.0714285714285714 3.91575630252101 0.0919644060221402 0.508548997596851 GO:0001786 phosphatidylserine binding 3/340 59/18639 0.0508474576271186 2.78748753738784 0.092859160759482 0.508548997596851 GO:0070888 E-box binding 3/340 59/18639 0.0508474576271186 2.78748753738784 0.092859160759482 0.508548997596851 GO:0001664 G protein-coupled receptor binding 9/340 297/18639 0.0303030303030303 1.66122994652406 0.0951468897074243 0.517038524689182 GO:0003785 actin monomer binding 2/340 29/18639 0.0689655172413793 3.78073022312373 0.0976300595046064 0.518474785702493 GO:0035250 UDP-galactosyltransferase activity 2/340 29/18639 0.0689655172413793 3.78073022312373 0.0976300595046064 0.518474785702493 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/340 29/18639 0.0689655172413793 3.78073022312373 0.0976300595046064 0.518474785702493 GO:0031624 ubiquitin conjugating enzyme binding 2/340 30/18639 0.0666666666666667 3.65470588235294 0.103391481536765 0.542252320530977 GO:0044325 transmembrane transporter binding 5/340 136/18639 0.0367647058823529 2.01546280276817 0.103678537358034 0.542252320530977 GO:0008170 N-methyltransferase activity 4/340 98/18639 0.0408163265306122 2.237575030012 0.104428050316237 0.542252320530977 GO:0005164 tumor necrosis factor receptor binding 2/340 31/18639 0.0645161290322581 3.53681214421252 0.109243318631695 0.558974936940277 GO:0016878 acid-thiol ligase activity 2/340 31/18639 0.0645161290322581 3.53681214421252 0.109243318631695 0.558974936940277 GO:0008378 galactosyltransferase activity 2/340 32/18639 0.0625 3.42628676470588 0.115180379708392 0.585082943301323 GO:0016755 aminoacyltransferase activity 13/340 496/18639 0.0262096774193548 1.43682993358634 0.122751297357375 0.618128724837072 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3/340 67/18639 0.0447761194029851 2.45465320456541 0.123449388697846 0.618128724837072 GO:0015035 protein-disulfide reductase activity 2/340 34/18639 0.0588235294117647 3.22474048442907 0.127290196920487 0.622509771823024 GO:0052866 phosphatidylinositol phosphate phosphatase activity 2/340 34/18639 0.0588235294117647 3.22474048442907 0.127290196920487 0.622509771823024 GO:0016791 phosphatase activity 8/340 273/18639 0.0293040293040293 1.60646412411118 0.127786856812166 0.622509771823024 GO:0005126 cytokine receptor binding 8/340 275/18639 0.0290909090909091 1.5947807486631 0.131594024175775 0.622509771823024 GO:0019888 protein phosphatase regulator activity 4/340 107/18639 0.0373831775700935 2.04936778449698 0.132037870828886 0.622509771823024 GO:0097110 scaffold protein binding 3/340 70/18639 0.0428571428571429 2.3494537815126 0.13575297454541 0.622509771823024 GO:0001217 DNA-binding transcription repressor activity 8/340 278/18639 0.0287769784172662 1.5775708844689 0.137413044979489 0.622509771823024 GO:0005484 SNAP receptor activity 2/340 36/18639 0.0555555555555556 3.04558823529412 0.139682498656368 0.622509771823024 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/340 36/18639 0.0555555555555556 3.04558823529412 0.139682498656368 0.622509771823024 GO:0055106 ubiquitin-protein transferase regulator activity 2/340 36/18639 0.0555555555555556 3.04558823529412 0.139682498656368 0.622509771823024 GO:0030246 carbohydrate binding 8/340 280/18639 0.0285714285714286 1.5663025210084 0.141363661781873 0.622509771823024 GO:1902936 phosphatidylinositol bisphosphate binding 4/340 111/18639 0.036036036036036 1.97551669316375 0.145180806795684 0.622509771823024 GO:0005200 structural constituent of cytoskeleton 4/340 112/18639 0.0357142857142857 1.9578781512605 0.148544086655544 0.622509771823024 GO:0003924 GTPase activity 9/340 331/18639 0.027190332326284 1.49059001244002 0.152939299633171 0.622509771823024 GO:0017171 serine hydrolase activity 6/340 198/18639 0.0303030303030303 1.66122994652406 0.154686985049364 0.622509771823024 GO:0005525 GTP binding 10/340 378/18639 0.0264550264550265 1.45028011204482 0.154979468980599 0.622509771823024 GO:0019207 kinase regulator activity 8/340 287/18639 0.0278745644599303 1.528100020496 0.155629142818973 0.622509771823024 GO:0001221 transcription coregulator binding 4/340 115/18639 0.0347826086956522 1.90680306905371 0.158810995444498 0.622509771823024 GO:0015036 disulfide oxidoreductase activity 2/340 40/18639 0.05 2.74102941176471 0.165172423622521 0.622509771823024 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/340 40/18639 0.05 2.74102941176471 0.165172423622521 0.622509771823024 GO:0019787 ubiquitin-like protein transferase activity 12/340 479/18639 0.0250521920668058 1.37337590568587 0.167672502430967 0.622509771823024 GO:0004090 carbonyl reductase (NADPH) activity 1/340 10/18639 0.1 5.48205882352941 0.168182601821615 0.622509771823024 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/340 10/18639 0.1 5.48205882352941 0.168182601821615 0.622509771823024 GO:0005345 purine nucleobase transmembrane transporter activity 1/340 10/18639 0.1 5.48205882352941 0.168182601821615 0.622509771823024 GO:0005528 FK506 binding 1/340 10/18639 0.1 5.48205882352941 0.168182601821615 0.622509771823024 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/340 10/18639 0.1 5.48205882352941 0.168182601821615 0.622509771823024 GO:0015203 polyamine transmembrane transporter activity 1/340 10/18639 0.1 5.48205882352941 0.168182601821615 0.622509771823024 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/340 10/18639 0.1 5.48205882352941 0.168182601821615 0.622509771823024 GO:0031434 mitogen-activated protein kinase kinase binding 1/340 10/18639 0.1 5.48205882352941 0.168182601821615 0.622509771823024 GO:0031720 haptoglobin binding 1/340 10/18639 0.1 5.48205882352941 0.168182601821615 0.622509771823024 GO:0031996 thioesterase binding 1/340 10/18639 0.1 5.48205882352941 0.168182601821615 0.622509771823024 GO:0050308 sugar-phosphatase activity 1/340 10/18639 0.1 5.48205882352941 0.168182601821615 0.622509771823024 GO:0051880 G-quadruplex DNA binding 1/340 10/18639 0.1 5.48205882352941 0.168182601821615 0.622509771823024 GO:0070097 delta-catenin binding 1/340 10/18639 0.1 5.48205882352941 0.168182601821615 0.622509771823024 GO:0022853 active monoatomic ion transmembrane transporter activity 4/340 118/18639 0.0338983050847458 1.85832502492522 0.169331379391889 0.622509771823024 GO:0001727 lipid kinase activity 2/340 41/18639 0.0487804878048781 2.67417503586801 0.171667735772411 0.622509771823024 GO:0004812 aminoacyl-tRNA ligase activity 2/340 41/18639 0.0487804878048781 2.67417503586801 0.171667735772411 0.622509771823024 GO:0016875 ligase activity, forming carbon-oxygen bonds 2/340 41/18639 0.0487804878048781 2.67417503586801 0.171667735772411 0.622509771823024 GO:0140318 protein transporter activity 2/340 41/18639 0.0487804878048781 2.67417503586801 0.171667735772411 0.622509771823024 GO:0046332 SMAD binding 3/340 79/18639 0.0379746835443038 2.08179448994788 0.174928690693984 0.622509771823024 GO:0019894 kinesin binding 2/340 42/18639 0.0476190476190476 2.61050420168067 0.178204433796575 0.622509771823024 GO:0031492 nucleosomal DNA binding 2/340 42/18639 0.0476190476190476 2.61050420168067 0.178204433796575 0.622509771823024 GO:0042056 chemoattractant activity 2/340 42/18639 0.0476190476190476 2.61050420168067 0.178204433796575 0.622509771823024 GO:0051879 Hsp90 protein binding 2/340 42/18639 0.0476190476190476 2.61050420168067 0.178204433796575 0.622509771823024 GO:0000099 sulfur amino acid transmembrane transporter activity 1/340 11/18639 0.0909090909090909 4.98368983957219 0.183364195862124 0.622509771823024 GO:0008199 ferric iron binding 1/340 11/18639 0.0909090909090909 4.98368983957219 0.183364195862124 0.622509771823024 GO:0008503 benzodiazepine receptor activity 1/340 11/18639 0.0909090909090909 4.98368983957219 0.183364195862124 0.622509771823024 GO:0015205 nucleobase transmembrane transporter activity 1/340 11/18639 0.0909090909090909 4.98368983957219 0.183364195862124 0.622509771823024 GO:0019203 carbohydrate phosphatase activity 1/340 11/18639 0.0909090909090909 4.98368983957219 0.183364195862124 0.622509771823024 GO:0019215 intermediate filament binding 1/340 11/18639 0.0909090909090909 4.98368983957219 0.183364195862124 0.622509771823024 GO:0032050 clathrin heavy chain binding 1/340 11/18639 0.0909090909090909 4.98368983957219 0.183364195862124 0.622509771823024 GO:0034713 type I transforming growth factor beta receptor binding 1/340 11/18639 0.0909090909090909 4.98368983957219 0.183364195862124 0.622509771823024 GO:0043522 leucine zipper domain binding 1/340 11/18639 0.0909090909090909 4.98368983957219 0.183364195862124 0.622509771823024 GO:0070697 activin receptor binding 1/340 11/18639 0.0909090909090909 4.98368983957219 0.183364195862124 0.622509771823024 GO:0070990 snRNP binding 1/340 11/18639 0.0909090909090909 4.98368983957219 0.183364195862124 0.622509771823024 GO:0140537 transcription regulator activator activity 1/340 11/18639 0.0909090909090909 4.98368983957219 0.183364195862124 0.622509771823024 GO:0180030 inositol phosphate kinase activity 1/340 11/18639 0.0909090909090909 4.98368983957219 0.183364195862124 0.622509771823024 GO:1990948 ubiquitin ligase inhibitor activity 1/340 11/18639 0.0909090909090909 4.98368983957219 0.183364195862124 0.622509771823024 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/340 43/18639 0.0465116279069767 2.54979480164159 0.184778861493902 0.622509771823024 GO:0008375 acetylglucosaminyltransferase activity 2/340 43/18639 0.0465116279069767 2.54979480164159 0.184778861493902 0.622509771823024 GO:0048156 tau protein binding 2/340 43/18639 0.0465116279069767 2.54979480164159 0.184778861493902 0.622509771823024 GO:0001223 transcription coactivator binding 2/340 44/18639 0.0454545454545455 2.4918449197861 0.191387481548657 0.622509771823024 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/340 44/18639 0.0454545454545455 2.4918449197861 0.191387481548657 0.622509771823024 GO:0016247 channel regulator activity 5/340 168/18639 0.0297619047619048 1.63156512605042 0.193460985111195 0.622509771823024 GO:0019001 guanyl nucleotide binding 10/340 400/18639 0.025 1.37051470588235 0.197009103981466 0.622509771823024 GO:0032561 guanyl ribonucleotide binding 10/340 400/18639 0.025 1.37051470588235 0.197009103981466 0.622509771823024 GO:0004859 phospholipase inhibitor activity 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0004875 complement receptor activity 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0005078 MAP-kinase scaffold activity 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0005095 GTPase inhibitor activity 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0005527 macrolide binding 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0015166 polyol transmembrane transporter activity 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0016273 arginine N-methyltransferase activity 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0016274 protein-arginine N-methyltransferase activity 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0016840 carbon-nitrogen lyase activity 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0035497 cAMP response element binding 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0042301 phosphate ion binding 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0045295 gamma-catenin binding 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0070008 serine-type exopeptidase activity 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0070410 co-SMAD binding 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0097371 MDM2/MDM4 family protein binding 1/340 12/18639 0.0833333333333333 4.56838235294118 0.198269509014737 0.622509771823024 GO:0004842 ubiquitin-protein transferase activity 11/340 449/18639 0.0244988864142539 1.34304336433905 0.199372688780184 0.622509771823024 GO:0141108 transporter regulator activity 5/340 170/18639 0.0294117647058824 1.61237024221453 0.199806988102968 0.622509771823024 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/340 46/18639 0.0434782608695652 2.38350383631714 0.204693725372627 0.629017057608852 GO:0031490 chromatin DNA binding 4/340 128/18639 0.03125 1.71314338235294 0.206025215686156 0.629017057608852 GO:0008253 5'-nucleotidase activity 1/340 13/18639 0.0769230769230769 4.21696832579186 0.212903554590245 0.629017057608852 GO:0039706 co-receptor binding 1/340 13/18639 0.0769230769230769 4.21696832579186 0.212903554590245 0.629017057608852 GO:0043560 insulin receptor substrate binding 1/340 13/18639 0.0769230769230769 4.21696832579186 0.212903554590245 0.629017057608852 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/340 13/18639 0.0769230769230769 4.21696832579186 0.212903554590245 0.629017057608852 GO:0032266 phosphatidylinositol-3-phosphate binding 2/340 48/18639 0.0416666666666667 2.28419117647059 0.218097128494779 0.629017057608852 GO:0140693 molecular condensate scaffold activity 2/340 48/18639 0.0416666666666667 2.28419117647059 0.218097128494779 0.629017057608852 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 7/340 268/18639 0.0261194029850746 1.43188103599649 0.219075058136413 0.629017057608852 GO:0042578 phosphoric ester hydrolase activity 9/340 363/18639 0.0247933884297521 1.35918813806514 0.21982006599259 0.629017057608852 GO:0001222 transcription corepressor binding 2/340 49/18639 0.0408163265306122 2.237575030012 0.224827598691442 0.629017057608852 GO:0019210 kinase inhibitor activity 3/340 90/18639 0.0333333333333333 1.82735294117647 0.226363036821326 0.629017057608852 GO:0005161 platelet-derived growth factor receptor binding 1/340 14/18639 0.0714285714285714 3.91575630252101 0.227271255193666 0.629017057608852 GO:0005313 L-glutamate transmembrane transporter activity 1/340 14/18639 0.0714285714285714 3.91575630252101 0.227271255193666 0.629017057608852 GO:0005344 oxygen carrier activity 1/340 14/18639 0.0714285714285714 3.91575630252101 0.227271255193666 0.629017057608852 GO:0005545 1-phosphatidylinositol binding 1/340 14/18639 0.0714285714285714 3.91575630252101 0.227271255193666 0.629017057608852 GO:0008195 phosphatidate phosphatase activity 1/340 14/18639 0.0714285714285714 3.91575630252101 0.227271255193666 0.629017057608852 GO:0034236 protein kinase A catalytic subunit binding 1/340 14/18639 0.0714285714285714 3.91575630252101 0.227271255193666 0.629017057608852 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/340 14/18639 0.0714285714285714 3.91575630252101 0.227271255193666 0.629017057608852 GO:0042043 neurexin family protein binding 1/340 14/18639 0.0714285714285714 3.91575630252101 0.227271255193666 0.629017057608852 GO:0044548 S100 protein binding 1/340 14/18639 0.0714285714285714 3.91575630252101 0.227271255193666 0.629017057608852 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/340 14/18639 0.0714285714285714 3.91575630252101 0.227271255193666 0.629017057608852 GO:0072341 modified amino acid binding 3/340 91/18639 0.032967032967033 1.80727213962508 0.231181643720064 0.629017057608852 GO:0032813 tumor necrosis factor receptor superfamily binding 2/340 50/18639 0.04 2.19282352941176 0.231573365411279 0.629017057608852 GO:0046982 protein heterodimerization activity 9/340 369/18639 0.024390243902439 1.337087517934 0.233485883859075 0.629017057608852 GO:0043178 alcohol binding 3/340 92/18639 0.0326086956521739 1.78762787723785 0.236019016883163 0.629017057608852 GO:0052689 carboxylic ester hydrolase activity 3/340 92/18639 0.0326086956521739 1.78762787723785 0.236019016883163 0.629017057608852 GO:0005048 signal sequence binding 2/340 51/18639 0.0392156862745098 2.14982698961938 0.238331640735601 0.629017057608852 GO:0004129 cytochrome-c oxidase activity 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0005523 tropomyosin binding 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0008252 nucleotidase activity 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0015250 water channel activity 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0034483 heparan sulfate sulfotransferase activity 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0047372 monoacylglycerol lipase activity 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0048531 beta-1,3-galactosyltransferase activity 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0050780 dopamine receptor binding 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0051371 muscle alpha-actinin binding 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0061578 K63-linked deubiquitinase activity 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0120283 protein serine/threonine kinase binding 1/340 15/18639 0.0666666666666667 3.65470588235294 0.241377444360601 0.629017057608852 GO:0042562 hormone binding 3/340 94/18639 0.0319148936170213 1.74959324155194 0.245745604535992 0.631767248293699 GO:0008276 protein methyltransferase activity 3/340 95/18639 0.0315789473684211 1.73117647058824 0.250632623368534 0.631767248293699 GO:0008146 sulfotransferase activity 2/340 53/18639 0.0377358490566038 2.06870144284129 0.251875043200354 0.631767248293699 GO:0016860 intramolecular oxidoreductase activity 2/340 53/18639 0.0377358490566038 2.06870144284129 0.251875043200354 0.631767248293699 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/340 16/18639 0.0625 3.42628676470588 0.255226868164155 0.631767248293699 GO:0008142 oxysterol binding 1/340 16/18639 0.0625 3.42628676470588 0.255226868164155 0.631767248293699 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/340 16/18639 0.0625 3.42628676470588 0.255226868164155 0.631767248293699 GO:0016722 oxidoreductase activity, acting on metal ions 1/340 16/18639 0.0625 3.42628676470588 0.255226868164155 0.631767248293699 GO:0030275 LRR domain binding 1/340 16/18639 0.0625 3.42628676470588 0.255226868164155 0.631767248293699 GO:0055102 lipase inhibitor activity 1/340 16/18639 0.0625 3.42628676470588 0.255226868164155 0.631767248293699 GO:0070411 I-SMAD binding 1/340 16/18639 0.0625 3.42628676470588 0.255226868164155 0.631767248293699 GO:0097027 ubiquitin-protein transferase activator activity 1/340 16/18639 0.0625 3.42628676470588 0.255226868164155 0.631767248293699 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/340 16/18639 0.0625 3.42628676470588 0.255226868164155 0.631767248293699 GO:0005125 cytokine activity 6/340 234/18639 0.0256410256410256 1.40565610859728 0.256193337983259 0.631767248293699 GO:0031406 carboxylic acid binding 5/340 187/18639 0.0267379679144385 1.46579112928594 0.256291386211513 0.631767248293699 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/340 54/18639 0.037037037037037 2.03039215686274 0.258655064565323 0.631767248293699 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/340 54/18639 0.037037037037037 2.03039215686274 0.258655064565323 0.631767248293699 GO:0050661 NADP binding 2/340 54/18639 0.037037037037037 2.03039215686274 0.258655064565323 0.631767248293699 GO:0043177 organic acid binding 5/340 189/18639 0.0264550264550265 1.45028011204482 0.263187083839066 0.636641063992781 GO:0030527 structural constituent of chromatin 3/340 98/18639 0.0306122448979592 1.678181272509 0.265375692543292 0.636641063992781 GO:0019902 phosphatase binding 5/340 190/18639 0.0263157894736842 1.44264705882353 0.266651028317074 0.636641063992781 GO:0019903 protein phosphatase binding 4/340 144/18639 0.0277777777777778 1.52279411764706 0.268733273800108 0.636641063992781 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/340 17/18639 0.0588235294117647 3.22474048442907 0.268824186792958 0.636641063992781 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/340 17/18639 0.0588235294117647 3.22474048442907 0.268824186792958 0.636641063992781 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/340 17/18639 0.0588235294117647 3.22474048442907 0.268824186792958 0.636641063992781 GO:0030169 low-density lipoprotein particle binding 1/340 17/18639 0.0588235294117647 3.22474048442907 0.268824186792958 0.636641063992781 GO:0031489 myosin V binding 1/340 17/18639 0.0588235294117647 3.22474048442907 0.268824186792958 0.636641063992781 GO:0008194 UDP-glycosyltransferase activity 4/340 145/18639 0.0275862068965517 1.51229208924949 0.272770447409065 0.638077281440811 GO:0043130 ubiquitin binding 3/340 100/18639 0.03 1.64461764705882 0.275262290881056 0.638077281440811 GO:0004601 peroxidase activity 2/340 57/18639 0.0350877192982456 1.92352941176471 0.278999634542259 0.638077281440811 GO:0008236 serine-type peptidase activity 5/340 194/18639 0.0257731958762887 1.4129017586416 0.280605574533198 0.638077281440811 GO:0000400 four-way junction DNA binding 1/340 18/18639 0.0555555555555556 3.04558823529412 0.282173976100787 0.638077281440811 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/340 18/18639 0.0555555555555556 3.04558823529412 0.282173976100787 0.638077281440811 GO:0005372 water transmembrane transporter activity 1/340 18/18639 0.0555555555555556 3.04558823529412 0.282173976100787 0.638077281440811 GO:0015172 acidic amino acid transmembrane transporter activity 1/340 18/18639 0.0555555555555556 3.04558823529412 0.282173976100787 0.638077281440811 GO:0031690 adrenergic receptor binding 1/340 18/18639 0.0555555555555556 3.04558823529412 0.282173976100787 0.638077281440811 GO:0035615 clathrin adaptor activity 1/340 18/18639 0.0555555555555556 3.04558823529412 0.282173976100787 0.638077281440811 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/340 18/18639 0.0555555555555556 3.04558823529412 0.282173976100787 0.638077281440811 GO:0050811 GABA receptor binding 1/340 18/18639 0.0555555555555556 3.04558823529412 0.282173976100787 0.638077281440811 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/340 18/18639 0.0555555555555556 3.04558823529412 0.282173976100787 0.638077281440811 GO:0098641 cadherin binding involved in cell-cell adhesion 1/340 18/18639 0.0555555555555556 3.04558823529412 0.282173976100787 0.638077281440811 GO:0008238 exopeptidase activity 3/340 102/18639 0.0294117647058824 1.61237024221453 0.285185706081995 0.642814083483854 GO:0016758 hexosyltransferase activity 5/340 197/18639 0.0253807106598985 1.39138548820543 0.291165009927271 0.64887708814719 GO:0015459 potassium channel regulator activity 2/340 59/18639 0.0338983050847458 1.85832502492522 0.292544143980801 0.64887708814719 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/340 59/18639 0.0338983050847458 1.85832502492522 0.292544143980801 0.64887708814719 GO:0045309 protein phosphorylated amino acid binding 2/340 59/18639 0.0338983050847458 1.85832502492522 0.292544143980801 0.64887708814719 GO:0019842 vitamin binding 4/340 150/18639 0.0266666666666667 1.46188235294118 0.293101013937643 0.64887708814719 GO:0042577 lipid phosphatase activity 1/340 19/18639 0.0526315789473684 2.88529411764706 0.295280729128322 0.64887708814719 GO:0140036 ubiquitin-modified protein reader activity 1/340 19/18639 0.0526315789473684 2.88529411764706 0.295280729128322 0.64887708814719 GO:1990380 K48-linked deubiquitinase activity 1/340 19/18639 0.0526315789473684 2.88529411764706 0.295280729128322 0.64887708814719 GO:0000149 SNARE binding 3/340 106/18639 0.0283018867924528 1.55152608213097 0.30511174714306 0.666704781406968 GO:0000339 RNA cap binding 1/340 20/18639 0.05 2.74102941176471 0.308148857597514 0.666704781406968 GO:0030742 GTP-dependent protein binding 1/340 20/18639 0.05 2.74102941176471 0.308148857597514 0.666704781406968 GO:0031418 L-ascorbic acid binding 1/340 20/18639 0.05 2.74102941176471 0.308148857597514 0.666704781406968 GO:0140664 ATP-dependent DNA damage sensor activity 1/340 20/18639 0.05 2.74102941176471 0.308148857597514 0.666704781406968 GO:0005496 steroid binding 3/340 108/18639 0.0277777777777778 1.52279411764706 0.315099357009082 0.67325948520578 GO:0005507 copper ion binding 2/340 63/18639 0.0317460317460317 1.74033613445378 0.319515530207982 0.67325948520578 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/340 21/18639 0.0476190476190476 2.61050420168067 0.320782693379074 0.67325948520578 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/340 21/18639 0.0476190476190476 2.61050420168067 0.320782693379074 0.67325948520578 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/340 21/18639 0.0476190476190476 2.61050420168067 0.320782693379074 0.67325948520578 GO:0010314 phosphatidylinositol-5-phosphate binding 1/340 21/18639 0.0476190476190476 2.61050420168067 0.320782693379074 0.67325948520578 GO:0019200 carbohydrate kinase activity 1/340 21/18639 0.0476190476190476 2.61050420168067 0.320782693379074 0.67325948520578 GO:0051010 microtubule plus-end binding 1/340 21/18639 0.0476190476190476 2.61050420168067 0.320782693379074 0.67325948520578 GO:0072542 protein phosphatase activator activity 1/340 21/18639 0.0476190476190476 2.61050420168067 0.320782693379074 0.67325948520578 GO:0140312 cargo adaptor activity 1/340 21/18639 0.0476190476190476 2.61050420168067 0.320782693379074 0.67325948520578 GO:0005516 calmodulin binding 5/340 207/18639 0.0241545893719807 1.32416879795396 0.326810239350771 0.678852836589031 GO:0015377 chloride:monoatomic cation symporter activity 1/340 22/18639 0.0454545454545455 2.4918449197861 0.333186489933543 0.678852836589031 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/340 22/18639 0.0454545454545455 2.4918449197861 0.333186489933543 0.678852836589031 GO:0050321 tau-protein kinase activity 1/340 22/18639 0.0454545454545455 2.4918449197861 0.333186489933543 0.678852836589031 GO:0070034 telomerase RNA binding 1/340 22/18639 0.0454545454545455 2.4918449197861 0.333186489933543 0.678852836589031 GO:0140035 ubiquitin-like protein reader activity 1/340 22/18639 0.0454545454545455 2.4918449197861 0.333186489933543 0.678852836589031 GO:0099106 ion channel regulator activity 4/340 160/18639 0.025 1.37051470588235 0.33426698885585 0.678852836589031 GO:0004866 endopeptidase inhibitor activity 4/340 161/18639 0.0248447204968944 1.36200219218122 0.338405147226862 0.678852836589031 GO:0008235 metalloexopeptidase activity 2/340 66/18639 0.0303030303030303 1.66122994652406 0.339584088414984 0.678852836589031 GO:0004602 glutathione peroxidase activity 1/340 23/18639 0.0434782608695652 2.38350383631714 0.345364423726453 0.678852836589031 GO:0005158 insulin receptor binding 1/340 23/18639 0.0434782608695652 2.38350383631714 0.345364423726453 0.678852836589031 GO:0017134 fibroblast growth factor binding 1/340 23/18639 0.0434782608695652 2.38350383631714 0.345364423726453 0.678852836589031 GO:0042171 lysophosphatidic acid acyltransferase activity 1/340 23/18639 0.0434782608695652 2.38350383631714 0.345364423726453 0.678852836589031 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/340 23/18639 0.0434782608695652 2.38350383631714 0.345364423726453 0.678852836589031 GO:0071617 lysophospholipid acyltransferase activity 1/340 23/18639 0.0434782608695652 2.38350383631714 0.345364423726453 0.678852836589031 GO:0017124 SH3 domain binding 3/340 115/18639 0.0260869565217391 1.43010230179028 0.350064826149123 0.678852836589031 GO:0035401 histone H3Y41 kinase activity 3/340 115/18639 0.0260869565217391 1.43010230179028 0.350064826149123 0.678852836589031 GO:0140801 histone H2AXY142 kinase activity 3/340 115/18639 0.0260869565217391 1.43010230179028 0.350064826149123 0.678852836589031 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 2/340 68/18639 0.0294117647058824 1.61237024221453 0.352862581896881 0.678852836589031 GO:0030145 manganese ion binding 2/340 68/18639 0.0294117647058824 1.61237024221453 0.352862581896881 0.678852836589031 GO:0032934 sterol binding 2/340 68/18639 0.0294117647058824 1.61237024221453 0.352862581896881 0.678852836589031 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/340 24/18639 0.0416666666666667 2.28419117647059 0.357320595617998 0.678852836589031 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/340 24/18639 0.0416666666666667 2.28419117647059 0.357320595617998 0.678852836589031 GO:0004622 lysophospholipase activity 1/340 24/18639 0.0416666666666667 2.28419117647059 0.357320595617998 0.678852836589031 GO:0004806 triacylglycerol lipase activity 1/340 24/18639 0.0416666666666667 2.28419117647059 0.357320595617998 0.678852836589031 GO:0005540 hyaluronic acid binding 1/340 24/18639 0.0416666666666667 2.28419117647059 0.357320595617998 0.678852836589031 GO:0030215 semaphorin receptor binding 1/340 24/18639 0.0416666666666667 2.28419117647059 0.357320595617998 0.678852836589031 GO:0030552 cAMP binding 1/340 24/18639 0.0416666666666667 2.28419117647059 0.357320595617998 0.678852836589031 GO:0035035 histone acetyltransferase binding 1/340 24/18639 0.0416666666666667 2.28419117647059 0.357320595617998 0.678852836589031 GO:0048027 mRNA 5'-UTR binding 1/340 24/18639 0.0416666666666667 2.28419117647059 0.357320595617998 0.678852836589031 GO:0050431 transforming growth factor beta binding 1/340 24/18639 0.0416666666666667 2.28419117647059 0.357320595617998 0.678852836589031 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/340 24/18639 0.0416666666666667 2.28419117647059 0.357320595617998 0.678852836589031 GO:0140612 DNA damage sensor activity 1/340 24/18639 0.0416666666666667 2.28419117647059 0.357320595617998 0.678852836589031 GO:0015399 primary active transmembrane transporter activity 4/340 166/18639 0.0240963855421687 1.32097802976612 0.359114695834188 0.678852836589031 GO:0016757 glycosyltransferase activity 6/340 267/18639 0.0224719101123595 1.2319233311302 0.360910305090362 0.678852836589031 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 4/340 167/18639 0.0239520958083832 1.31306798168369 0.363257014083228 0.678852836589031 GO:0016782 transferase activity, transferring sulphur-containing groups 2/340 70/18639 0.0285714285714286 1.5663025210084 0.366047100922403 0.678852836589031 GO:0001848 complement binding 1/340 25/18639 0.04 2.19282352941176 0.369059032227715 0.678852836589031 GO:0003707 nuclear steroid receptor activity 1/340 25/18639 0.04 2.19282352941176 0.369059032227715 0.678852836589031 GO:0004709 MAP kinase kinase kinase activity 1/340 25/18639 0.04 2.19282352941176 0.369059032227715 0.678852836589031 GO:0008139 nuclear localization sequence binding 1/340 25/18639 0.04 2.19282352941176 0.369059032227715 0.678852836589031 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/340 25/18639 0.04 2.19282352941176 0.369059032227715 0.678852836589031 GO:0017056 structural constituent of nuclear pore 1/340 25/18639 0.04 2.19282352941176 0.369059032227715 0.678852836589031 GO:0019211 phosphatase activator activity 1/340 25/18639 0.04 2.19282352941176 0.369059032227715 0.678852836589031 GO:0047617 fatty acyl-CoA hydrolase activity 1/340 25/18639 0.04 2.19282352941176 0.369059032227715 0.678852836589031 GO:0120020 cholesterol transfer activity 1/340 25/18639 0.04 2.19282352941176 0.369059032227715 0.678852836589031 GO:0030414 peptidase inhibitor activity 4/340 169/18639 0.0236686390532544 1.29752871562826 0.371538340801185 0.678852836589031 GO:0140299 molecular sensor activity 2/340 71/18639 0.028169014084507 1.54424192212096 0.372600788606612 0.678852836589031 GO:0032182 ubiquitin-like protein binding 3/340 120/18639 0.025 1.37051470588235 0.374934945867534 0.678852836589031 GO:0003697 single-stranded DNA binding 3/340 121/18639 0.0247933884297521 1.35918813806514 0.379888646059969 0.678852836589031 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/340 26/18639 0.0384615384615385 2.10848416289593 0.380583687274592 0.678852836589031 GO:0005160 transforming growth factor beta receptor binding 1/340 26/18639 0.0384615384615385 2.10848416289593 0.380583687274592 0.678852836589031 GO:0008198 ferrous iron binding 1/340 26/18639 0.0384615384615385 2.10848416289593 0.380583687274592 0.678852836589031 GO:0016289 acyl-CoA hydrolase activity 1/340 26/18639 0.0384615384615385 2.10848416289593 0.380583687274592 0.678852836589031 GO:0030507 spectrin binding 1/340 26/18639 0.0384615384615385 2.10848416289593 0.380583687274592 0.678852836589031 GO:0034237 protein kinase A regulatory subunit binding 1/340 26/18639 0.0384615384615385 2.10848416289593 0.380583687274592 0.678852836589031 GO:0043548 phosphatidylinositol 3-kinase binding 1/340 26/18639 0.0384615384615385 2.10848416289593 0.380583687274592 0.678852836589031 GO:0050681 nuclear androgen receptor binding 1/340 26/18639 0.0384615384615385 2.10848416289593 0.380583687274592 0.678852836589031 GO:0070412 R-SMAD binding 1/340 26/18639 0.0384615384615385 2.10848416289593 0.380583687274592 0.678852836589031 GO:0043539 protein serine/threonine kinase activator activity 2/340 73/18639 0.0273972602739726 1.50193392425463 0.385624844719934 0.682027604415792 GO:0001671 ATPase activator activity 1/340 27/18639 0.037037037037037 2.03039215686274 0.391898442893065 0.682027604415792 GO:0004364 glutathione transferase activity 1/340 27/18639 0.037037037037037 2.03039215686274 0.391898442893065 0.682027604415792 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/340 27/18639 0.037037037037037 2.03039215686274 0.391898442893065 0.682027604415792 GO:0008320 protein transmembrane transporter activity 1/340 27/18639 0.037037037037037 2.03039215686274 0.391898442893065 0.682027604415792 GO:0015252 proton channel activity 1/340 27/18639 0.037037037037037 2.03039215686274 0.391898442893065 0.682027604415792 GO:0023026 MHC class II protein complex binding 1/340 27/18639 0.037037037037037 2.03039215686274 0.391898442893065 0.682027604415792 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/340 27/18639 0.037037037037037 2.03039215686274 0.391898442893065 0.682027604415792 GO:0031491 nucleosome binding 2/340 74/18639 0.027027027027027 1.48163751987281 0.392092902395955 0.682027604415792 GO:0048029 monosaccharide binding 2/340 74/18639 0.027027027027027 1.48163751987281 0.392092902395955 0.682027604415792 GO:0019003 GDP binding 2/340 75/18639 0.0266666666666667 1.46188235294118 0.398530191046569 0.684038704016103 GO:0005242 inward rectifier potassium channel activity 1/340 28/18639 0.0357142857142857 1.9578781512605 0.403007110925322 0.684038704016103 GO:0019789 SUMO transferase activity 1/340 28/18639 0.0357142857142857 1.9578781512605 0.403007110925322 0.684038704016103 GO:0045499 chemorepellent activity 1/340 28/18639 0.0357142857142857 1.9578781512605 0.403007110925322 0.684038704016103 GO:0051019 mitogen-activated protein kinase binding 1/340 28/18639 0.0357142857142857 1.9578781512605 0.403007110925322 0.684038704016103 GO:0051393 alpha-actinin binding 1/340 28/18639 0.0357142857142857 1.9578781512605 0.403007110925322 0.684038704016103 GO:0051537 2 iron, 2 sulfur cluster binding 1/340 28/18639 0.0357142857142857 1.9578781512605 0.403007110925322 0.684038704016103 GO:0051959 dynein light intermediate chain binding 1/340 28/18639 0.0357142857142857 1.9578781512605 0.403007110925322 0.684038704016103 GO:0097718 disordered domain specific binding 1/340 28/18639 0.0357142857142857 1.9578781512605 0.403007110925322 0.684038704016103 GO:0141052 histone H3 demethylase activity 1/340 28/18639 0.0357142857142857 1.9578781512605 0.403007110925322 0.684038704016103 GO:0017022 myosin binding 2/340 76/18639 0.0263157894736842 1.44264705882353 0.404935680690108 0.685651961748227 GO:0004181 metallocarboxypeptidase activity 1/340 29/18639 0.0344827586206897 1.89036511156187 0.413913434190347 0.697483935979407 GO:0051861 glycolipid binding 1/340 29/18639 0.0344827586206897 1.89036511156187 0.413913434190347 0.697483935979407 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/340 130/18639 0.0230769230769231 1.26509049773756 0.424016132139624 0.700375017644278 GO:0001965 G-protein alpha-subunit binding 1/340 30/18639 0.0333333333333333 1.82735294117647 0.424621087730126 0.700375017644278 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/340 30/18639 0.0333333333333333 1.82735294117647 0.424621087730126 0.700375017644278 GO:0016769 transferase activity, transferring nitrogenous groups 1/340 30/18639 0.0333333333333333 1.82735294117647 0.424621087730126 0.700375017644278 GO:0032452 histone demethylase activity 1/340 30/18639 0.0333333333333333 1.82735294117647 0.424621087730126 0.700375017644278 GO:0033612 receptor serine/threonine kinase binding 1/340 30/18639 0.0333333333333333 1.82735294117647 0.424621087730126 0.700375017644278 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/340 30/18639 0.0333333333333333 1.82735294117647 0.424621087730126 0.700375017644278 GO:0048019 receptor antagonist activity 1/340 30/18639 0.0333333333333333 1.82735294117647 0.424621087730126 0.700375017644278 GO:0051721 protein phosphatase 2A binding 1/340 30/18639 0.0333333333333333 1.82735294117647 0.424621087730126 0.700375017644278 GO:0061135 endopeptidase regulator activity 4/340 184/18639 0.0217391304347826 1.19175191815857 0.43317794424948 0.704884385373466 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/340 31/18639 0.032258064516129 1.76840607210626 0.435133680033407 0.704884385373466 GO:0016411 acylglycerol O-acyltransferase activity 1/340 31/18639 0.032258064516129 1.76840607210626 0.435133680033407 0.704884385373466 GO:0047499 calcium-independent phospholipase A2 activity 1/340 31/18639 0.032258064516129 1.76840607210626 0.435133680033407 0.704884385373466 GO:0070273 phosphatidylinositol-4-phosphate binding 1/340 31/18639 0.032258064516129 1.76840607210626 0.435133680033407 0.704884385373466 GO:0072349 modified amino acid transmembrane transporter activity 1/340 31/18639 0.032258064516129 1.76840607210626 0.435133680033407 0.704884385373466 GO:0140457 protein demethylase activity 1/340 31/18639 0.032258064516129 1.76840607210626 0.435133680033407 0.704884385373466 GO:0030971 receptor tyrosine kinase binding 2/340 81/18639 0.0246913580246914 1.35359477124183 0.4364533476665 0.704884385373466 GO:0015078 proton transmembrane transporter activity 4/340 185/18639 0.0216216216216216 1.18531001589825 0.437238427898942 0.704884385373466 GO:0022884 macromolecule transmembrane transporter activity 1/340 32/18639 0.03125 1.71314338235294 0.44545475423744 0.704884385373466 GO:0030515 snoRNA binding 1/340 32/18639 0.03125 1.71314338235294 0.44545475423744 0.704884385373466 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/340 32/18639 0.03125 1.71314338235294 0.44545475423744 0.704884385373466 GO:0043425 bHLH transcription factor binding 1/340 32/18639 0.03125 1.71314338235294 0.44545475423744 0.704884385373466 GO:0047498 calcium-dependent phospholipase A2 activity 1/340 32/18639 0.03125 1.71314338235294 0.44545475423744 0.704884385373466 GO:0051059 NF-kappaB binding 1/340 32/18639 0.03125 1.71314338235294 0.44545475423744 0.704884385373466 GO:0071813 lipoprotein particle binding 1/340 32/18639 0.03125 1.71314338235294 0.44545475423744 0.704884385373466 GO:0071814 protein-lipid complex binding 1/340 32/18639 0.03125 1.71314338235294 0.44545475423744 0.704884385373466 GO:0120015 sterol transfer activity 1/340 32/18639 0.03125 1.71314338235294 0.44545475423744 0.704884385373466 GO:0030165 PDZ domain binding 2/340 83/18639 0.0240963855421687 1.32097802976612 0.448806865241769 0.708589217420001 GO:0002020 protease binding 3/340 136/18639 0.0220588235294118 1.2092776816609 0.452836031933391 0.71287285782357 GO:0051117 ATPase binding 2/340 84/18639 0.0238095238095238 1.30525210084034 0.454926309575209 0.71287285782357 GO:0071889 14-3-3 protein binding 1/340 33/18639 0.0303030303030303 1.66122994652406 0.455587789308073 0.71287285782357 GO:0140311 protein sequestering activity 1/340 33/18639 0.0303030303030303 1.66122994652406 0.455587789308073 0.71287285782357 GO:0016922 nuclear receptor binding 3/340 137/18639 0.0218978102189781 1.20045083726921 0.457582832505611 0.714399923355086 GO:0008376 acetylgalactosaminyltransferase activity 1/340 34/18639 0.0294117647058824 1.61237024221453 0.465536201198606 0.717232696791698 GO:0015020 glucuronosyltransferase activity 1/340 34/18639 0.0294117647058824 1.61237024221453 0.465536201198606 0.717232696791698 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/340 34/18639 0.0294117647058824 1.61237024221453 0.465536201198606 0.717232696791698 GO:0019825 oxygen binding 1/340 34/18639 0.0294117647058824 1.61237024221453 0.465536201198606 0.717232696791698 GO:0030332 cyclin binding 1/340 34/18639 0.0294117647058824 1.61237024221453 0.465536201198606 0.717232696791698 GO:0090482 vitamin transmembrane transporter activity 1/340 34/18639 0.0294117647058824 1.61237024221453 0.465536201198606 0.717232696791698 GO:0030295 protein kinase activator activity 3/340 139/18639 0.0215827338129496 1.18317816335167 0.467023735113261 0.717946575250868 GO:0004713 protein tyrosine kinase activity 3/340 140/18639 0.0214285714285714 1.1747268907563 0.471716956769936 0.723574587955635 GO:0004623 phospholipase A2 activity 1/340 35/18639 0.0285714285714286 1.5663025210084 0.475303343987774 0.724320965511803 GO:0016229 steroid dehydrogenase activity 1/340 35/18639 0.0285714285714286 1.5663025210084 0.475303343987774 0.724320965511803 GO:0140566 histone reader activity 1/340 35/18639 0.0285714285714286 1.5663025210084 0.475303343987774 0.724320965511803 GO:0004197 cysteine-type endopeptidase activity 2/340 88/18639 0.0227272727272727 1.24592245989305 0.479007262844047 0.728381976689104 GO:0004033 aldo-keto reductase (NADPH) activity 1/340 36/18639 0.0277777777777778 1.52279411764706 0.484892510997243 0.72941985023405 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/340 36/18639 0.0277777777777778 1.52279411764706 0.484892510997243 0.72941985023405 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/340 36/18639 0.0277777777777778 1.52279411764706 0.484892510997243 0.72941985023405 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/340 36/18639 0.0277777777777778 1.52279411764706 0.484892510997243 0.72941985023405 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/340 36/18639 0.0277777777777778 1.52279411764706 0.484892510997243 0.72941985023405 GO:0030280 structural constituent of skin epidermis 1/340 37/18639 0.027027027027027 1.48163751987281 0.494306935888977 0.735688242161726 GO:0030551 cyclic nucleotide binding 1/340 37/18639 0.027027027027027 1.48163751987281 0.494306935888977 0.735688242161726 GO:0042805 actinin binding 1/340 37/18639 0.027027027027027 1.48163751987281 0.494306935888977 0.735688242161726 GO:0043394 proteoglycan binding 1/340 37/18639 0.027027027027027 1.48163751987281 0.494306935888977 0.735688242161726 GO:0070001 aspartic-type peptidase activity 1/340 37/18639 0.027027027027027 1.48163751987281 0.494306935888977 0.735688242161726 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/340 91/18639 0.021978021978022 1.20484809308339 0.496636073983865 0.737588745471799 GO:0019887 protein kinase regulator activity 5/340 255/18639 0.0196078431372549 1.07491349480969 0.49833435677548 0.738546266595373 GO:0000146 microfilament motor activity 1/340 38/18639 0.0263157894736842 1.44264705882353 0.50354979374285 0.742269703660115 GO:0042887 amide transmembrane transporter activity 1/340 38/18639 0.0263157894736842 1.44264705882353 0.50354979374285 0.742269703660115 GO:0015085 calcium ion transmembrane transporter activity 3/340 147/18639 0.0204081632653061 1.118787515006 0.50402336511015 0.742269703660115 GO:0051219 phosphoprotein binding 2/340 93/18639 0.021505376344086 1.17893738140417 0.50817599327303 0.745811324155465 GO:0019209 kinase activator activity 3/340 148/18639 0.0202702702702703 1.11122813990461 0.508556081235824 0.745811324155465 GO:0008168 methyltransferase activity 4/340 204/18639 0.0196078431372549 1.07491349480969 0.512461305154433 0.747088494142422 GO:0000217 DNA secondary structure binding 1/340 39/18639 0.0256410256410256 1.40565610859728 0.512624202114843 0.747088494142422 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/340 39/18639 0.0256410256410256 1.40565610859728 0.512624202114843 0.747088494142422 GO:0015144 carbohydrate transmembrane transporter activity 1/340 40/18639 0.025 1.37051470588235 0.521533222076185 0.752252651595484 GO:0032451 demethylase activity 1/340 40/18639 0.025 1.37051470588235 0.521533222076185 0.752252651595484 GO:0061791 GTPase motor activity 1/340 40/18639 0.025 1.37051470588235 0.521533222076185 0.752252651595484 GO:0071855 neuropeptide receptor binding 1/340 40/18639 0.025 1.37051470588235 0.521533222076185 0.752252651595484 GO:1990606 membrane scission GTPase motor activity 1/340 40/18639 0.025 1.37051470588235 0.521533222076185 0.752252651595484 GO:0001530 lipopolysaccharide binding 1/340 41/18639 0.024390243902439 1.337087517934 0.530279859233779 0.757079799028267 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/340 41/18639 0.024390243902439 1.337087517934 0.530279859233779 0.757079799028267 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/340 41/18639 0.024390243902439 1.337087517934 0.530279859233779 0.757079799028267 GO:0017080 sodium channel regulator activity 1/340 41/18639 0.024390243902439 1.337087517934 0.530279859233779 0.757079799028267 GO:0042287 MHC protein binding 1/340 41/18639 0.024390243902439 1.337087517934 0.530279859233779 0.757079799028267 GO:0042626 ATPase-coupled transmembrane transporter activity 2/340 98/18639 0.0204081632653061 1.118787515006 0.536260574117008 0.764062322065086 GO:0008307 structural constituent of muscle 1/340 42/18639 0.0238095238095238 1.30525210084034 0.538867064732247 0.764667636391306 GO:0016859 cis-trans isomerase activity 1/340 42/18639 0.0238095238095238 1.30525210084034 0.538867064732247 0.764667636391306 GO:0008200 ion channel inhibitor activity 1/340 43/18639 0.0232558139534884 1.27489740082079 0.547297736237922 0.77506204667229 GO:0016741 transferase activity, transferring one-carbon groups 4/340 215/18639 0.0186046511627907 1.01991792065663 0.553866426314804 0.777361033837296 GO:0001046 core promoter sequence-specific DNA binding 1/340 44/18639 0.0227272727272727 1.24592245989305 0.555574718905114 0.777361033837296 GO:0003954 NADH dehydrogenase activity 1/340 44/18639 0.0227272727272727 1.24592245989305 0.555574718905114 0.777361033837296 GO:0016248 channel inhibitor activity 1/340 44/18639 0.0227272727272727 1.24592245989305 0.555574718905114 0.777361033837296 GO:0016790 thiolester hydrolase activity 1/340 44/18639 0.0227272727272727 1.24592245989305 0.555574718905114 0.777361033837296 GO:0043014 alpha-tubulin binding 1/340 44/18639 0.0227272727272727 1.24592245989305 0.555574718905114 0.777361033837296 GO:0042605 peptide antigen binding 1/340 45/18639 0.0222222222222222 1.21823529411765 0.563700806324972 0.784036240543265 GO:0140303 intramembrane lipid transporter activity 1/340 45/18639 0.0222222222222222 1.21823529411765 0.563700806324972 0.784036240543265 GO:0141110 transporter inhibitor activity 1/340 45/18639 0.0222222222222222 1.21823529411765 0.563700806324972 0.784036240543265 GO:0005178 integrin binding 3/340 161/18639 0.0186335403726708 1.02150164413592 0.565407918061687 0.784853367448005 GO:0030276 clathrin binding 1/340 46/18639 0.0217391304347826 1.19175191815857 0.571678741457247 0.786641464095274 GO:0030291 protein serine/threonine kinase inhibitor activity 1/340 46/18639 0.0217391304347826 1.19175191815857 0.571678741457247 0.786641464095274 GO:0004497 monooxygenase activity 2/340 106/18639 0.0188679245283019 1.03435072142064 0.578858175488298 0.786641464095274 GO:0008013 beta-catenin binding 2/340 106/18639 0.0188679245283019 1.03435072142064 0.578858175488298 0.786641464095274 GO:0001784 phosphotyrosine residue binding 1/340 47/18639 0.0212765957446809 1.16639549436796 0.579511217545266 0.786641464095274 GO:0043495 protein-membrane adaptor activity 1/340 47/18639 0.0212765957446809 1.16639549436796 0.579511217545266 0.786641464095274 GO:0140359 ABC-type transporter activity 1/340 47/18639 0.0212765957446809 1.16639549436796 0.579511217545266 0.786641464095274 GO:0140938 histone H3 methyltransferase activity 1/340 47/18639 0.0212765957446809 1.16639549436796 0.579511217545266 0.786641464095274 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/340 48/18639 0.0208333333333333 1.14209558823529 0.587200879014425 0.786641464095274 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/340 48/18639 0.0208333333333333 1.14209558823529 0.587200879014425 0.786641464095274 GO:0038187 pattern recognition receptor activity 1/340 48/18639 0.0208333333333333 1.14209558823529 0.587200879014425 0.786641464095274 GO:0004843 cysteine-type deubiquitinase activity 2/340 108/18639 0.0185185185185185 1.01519607843137 0.589050466325676 0.786641464095274 GO:0061134 peptidase regulator activity 4/340 226/18639 0.0176991150442478 0.970275897969807 0.593339311337619 0.786641464095274 GO:0005004 GPI-linked ephrin receptor activity 1/340 49/18639 0.0204081632653061 1.118787515006 0.594750322354487 0.786641464095274 GO:0005008 hepatocyte growth factor receptor activity 1/340 49/18639 0.0204081632653061 1.118787515006 0.594750322354487 0.786641464095274 GO:0005009 insulin receptor activity 1/340 49/18639 0.0204081632653061 1.118787515006 0.594750322354487 0.786641464095274 GO:0005011 macrophage colony-stimulating factor receptor activity 1/340 49/18639 0.0204081632653061 1.118787515006 0.594750322354487 0.786641464095274 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/340 49/18639 0.0204081632653061 1.118787515006 0.594750322354487 0.786641464095274 GO:0005020 stem cell factor receptor activity 1/340 49/18639 0.0204081632653061 1.118787515006 0.594750322354487 0.786641464095274 GO:0008288 boss receptor activity 1/340 49/18639 0.0204081632653061 1.118787515006 0.594750322354487 0.786641464095274 GO:0016763 pentosyltransferase activity 1/340 49/18639 0.0204081632653061 1.118787515006 0.594750322354487 0.786641464095274 GO:0036332 placental growth factor receptor activity 1/340 49/18639 0.0204081632653061 1.118787515006 0.594750322354487 0.786641464095274 GO:0038062 protein tyrosine kinase collagen receptor activity 1/340 49/18639 0.0204081632653061 1.118787515006 0.594750322354487 0.786641464095274 GO:0060175 brain-derived neurotrophic factor receptor activity 1/340 49/18639 0.0204081632653061 1.118787515006 0.594750322354487 0.786641464095274 GO:0060590 ATPase regulator activity 1/340 49/18639 0.0204081632653061 1.118787515006 0.594750322354487 0.786641464095274 GO:0005006 epidermal growth factor receptor activity 1/340 50/18639 0.02 1.09641176470588 0.602162096985981 0.790478707841147 GO:0005007 fibroblast growth factor receptor activity 1/340 50/18639 0.02 1.09641176470588 0.602162096985981 0.790478707841147 GO:0005017 platelet-derived growth factor receptor activity 1/340 50/18639 0.02 1.09641176470588 0.602162096985981 0.790478707841147 GO:0005019 platelet-derived growth factor beta-receptor activity 1/340 50/18639 0.02 1.09641176470588 0.602162096985981 0.790478707841147 GO:0003743 translation initiation factor activity 1/340 51/18639 0.0196078431372549 1.07491349480969 0.609438706110989 0.793647960415693 GO:0005010 insulin-like growth factor receptor activity 1/340 51/18639 0.0196078431372549 1.07491349480969 0.609438706110989 0.793647960415693 GO:0005021 vascular endothelial growth factor receptor activity 1/340 51/18639 0.0196078431372549 1.07491349480969 0.609438706110989 0.793647960415693 GO:0005030 neurotrophin receptor activity 1/340 51/18639 0.0196078431372549 1.07491349480969 0.609438706110989 0.793647960415693 GO:0004175 endopeptidase activity 7/340 405/18639 0.0172839506172839 0.947516339869281 0.61023716214559 0.793647960415693 GO:0005080 protein kinase C binding 1/340 52/18639 0.0192307692307692 1.05424208144796 0.616582607548597 0.794801720733202 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/340 52/18639 0.0192307692307692 1.05424208144796 0.616582607548597 0.794801720733202 GO:0030159 signaling receptor complex adaptor activity 1/340 52/18639 0.0192307692307692 1.05424208144796 0.616582607548597 0.794801720733202 GO:0101005 deubiquitinase activity 2/340 115/18639 0.0173913043478261 0.953401534526854 0.623275284783334 0.794801720733202 GO:0005003 ephrin receptor activity 1/340 53/18639 0.0188679245283019 1.03435072142064 0.623596214555294 0.794801720733202 GO:0005005 transmembrane-ephrin receptor activity 1/340 53/18639 0.0188679245283019 1.03435072142064 0.623596214555294 0.794801720733202 GO:0005246 calcium channel regulator activity 1/340 53/18639 0.0188679245283019 1.03435072142064 0.623596214555294 0.794801720733202 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/340 53/18639 0.0188679245283019 1.03435072142064 0.623596214555294 0.794801720733202 GO:0017046 peptide hormone binding 1/340 53/18639 0.0188679245283019 1.03435072142064 0.623596214555294 0.794801720733202 GO:0038064 collagen receptor activity 1/340 53/18639 0.0188679245283019 1.03435072142064 0.623596214555294 0.794801720733202 GO:0051018 protein kinase A binding 1/340 53/18639 0.0188679245283019 1.03435072142064 0.623596214555294 0.794801720733202 GO:0004252 serine-type endopeptidase activity 3/340 176/18639 0.0170454545454545 0.934441844919786 0.625780628535722 0.794906132262652 GO:0061630 ubiquitin protein ligase activity 6/340 353/18639 0.0169971671388102 0.931794700883186 0.626033389554098 0.794906132262652 GO:0009055 electron transfer activity 2/340 116/18639 0.0172413793103448 0.945182555780933 0.627980991747388 0.794906132262652 GO:0015485 cholesterol binding 1/340 54/18639 0.0185185185185185 1.01519607843137 0.630481896630577 0.794906132262652 GO:0051287 NAD binding 1/340 54/18639 0.0185185185185185 1.01519607843137 0.630481896630577 0.794906132262652 GO:0140463 chromatin-protein adaptor activity 1/340 54/18639 0.0185185185185185 1.01519607843137 0.630481896630577 0.794906132262652 GO:0005319 lipid transporter activity 3/340 178/18639 0.0168539325842697 0.923942498347654 0.633382277939769 0.797129222326352 GO:0008374 O-acyltransferase activity 1/340 55/18639 0.0181818181818182 0.996737967914438 0.637241980308037 0.79911740285498 GO:0098632 cell-cell adhesion mediator activity 1/340 55/18639 0.0181818181818182 0.996737967914438 0.637241980308037 0.79911740285498 GO:0016853 isomerase activity 3/340 180/18639 0.0166666666666667 0.913676470588235 0.64087639416054 0.802239914833104 GO:0170055 lipid transmembrane transporter activity 1/340 56/18639 0.0178571428571429 0.978939075630252 0.643878749932191 0.804008340786838 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/340 181/18639 0.0165745856353591 0.908628534286643 0.644583006451074 0.804008340786838 GO:0004540 RNA nuclease activity 2/340 121/18639 0.0165289256198347 0.906125425376762 0.650826192851244 0.810353749891159 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/340 122/18639 0.0163934426229508 0.898698167791707 0.655259397121563 0.810582193467459 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/340 122/18639 0.0163934426229508 0.898698167791707 0.655259397121563 0.810582193467459 GO:0008237 metallopeptidase activity 3/340 184/18639 0.016304347826087 0.893813938618926 0.655540631937397 0.810582193467459 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/340 58/18639 0.0172413793103448 0.945182555780933 0.656791278016429 0.810582193467459 GO:0061980 regulatory RNA binding 1/340 58/18639 0.0172413793103448 0.945182555780933 0.656791278016429 0.810582193467459 GO:0004879 nuclear receptor activity 1/340 59/18639 0.0169491525423729 0.929162512462612 0.663071401017044 0.815461494934996 GO:0031593 polyubiquitin modification-dependent protein binding 1/340 59/18639 0.0169491525423729 0.929162512462612 0.663071401017044 0.815461494934996 GO:0008234 cysteine-type peptidase activity 3/340 187/18639 0.0160427807486631 0.879474677571564 0.666254476415096 0.817308528384664 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/340 60/18639 0.0166666666666667 0.913676470588235 0.669236940503277 0.817308528384664 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/340 60/18639 0.0166666666666667 0.913676470588235 0.669236940503277 0.817308528384664 GO:0098531 ligand-modulated transcription factor activity 1/340 60/18639 0.0166666666666667 0.913676470588235 0.669236940503277 0.817308528384664 GO:0015026 coreceptor activity 1/340 61/18639 0.0163934426229508 0.898698167791707 0.675289981045226 0.81935212092398 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/340 61/18639 0.0163934426229508 0.898698167791707 0.675289981045226 0.81935212092398 GO:0061659 ubiquitin-like protein ligase activity 6/340 372/18639 0.0161290322580645 0.884203036053131 0.675760579470619 0.81935212092398 GO:0019783 ubiquitin-like protein peptidase activity 2/340 127/18639 0.015748031496063 0.863316350162112 0.676754462218237 0.81935212092398 GO:0042826 histone deacetylase binding 2/340 127/18639 0.015748031496063 0.863316350162112 0.676754462218237 0.81935212092398 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/340 128/18639 0.015625 0.856571691176471 0.680920524224618 0.821934649137709 GO:0015179 L-amino acid transmembrane transporter activity 1/340 62/18639 0.0161290322580645 0.884203036053131 0.681232569399442 0.821934649137709 GO:1901682 sulfur compound transmembrane transporter activity 1/340 63/18639 0.0158730158730159 0.870168067226891 0.687066715192853 0.826592486630013 GO:0016298 lipase activity 2/340 130/18639 0.0153846153846154 0.843393665158371 0.689121261497218 0.826592486630013 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/340 130/18639 0.0153846153846154 0.843393665158371 0.689121261497218 0.826592486630013 GO:0003713 transcription coactivator activity 4/340 256/18639 0.015625 0.856571691176471 0.68980970710208 0.826592486630013 GO:0005262 calcium channel activity 2/340 131/18639 0.0152671755725191 0.836955545577009 0.693156361375766 0.827772758644654 GO:0031072 heat shock protein binding 2/340 131/18639 0.0152671755725191 0.836955545577009 0.693156361375766 0.827772758644654 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/340 132/18639 0.0151515151515152 0.830614973262032 0.697148243134968 0.828410647576998 GO:0019843 rRNA binding 1/340 65/18639 0.0153846153846154 0.843393665158371 0.69841753597433 0.828410647576998 GO:0120013 lipid transfer activity 1/340 65/18639 0.0153846153846154 0.843393665158371 0.69841753597433 0.828410647576998 GO:0160215 deacylase activity 1/340 65/18639 0.0153846153846154 0.843393665158371 0.69841753597433 0.828410647576998 GO:0051087 protein-folding chaperone binding 2/340 134/18639 0.0149253731343284 0.818217734855136 0.705003273528959 0.834809619499662 GO:0016500 protein-hormone receptor activity 1/340 67/18639 0.0149253731343284 0.818217734855136 0.709357803032233 0.837137743982483 GO:0042054 histone methyltransferase activity 1/340 67/18639 0.0149253731343284 0.818217734855136 0.709357803032233 0.837137743982483 GO:0140789 histone phosphatase activity 2/340 136/18639 0.0147058823529412 0.806185121107266 0.712688253790755 0.839178756594683 GO:0140223 general transcription initiation factor activity 1/340 68/18639 0.0147058823529412 0.806185121107266 0.714678627228282 0.839178756594683 GO:1990841 promoter-specific chromatin binding 1/340 68/18639 0.0147058823529412 0.806185121107266 0.714678627228282 0.839178756594683 GO:0002039 p53 binding 1/340 69/18639 0.0144927536231884 0.794501278772379 0.719902323676637 0.842490031548117 GO:0016279 protein-lysine N-methyltransferase activity 1/340 69/18639 0.0144927536231884 0.794501278772379 0.719902323676637 0.842490031548117 GO:0140101 catalytic activity, acting on a tRNA 2/340 139/18639 0.0143884892086331 0.788785442234448 0.723901251824768 0.844263277121333 GO:0140767 enzyme-substrate adaptor activity 2/340 139/18639 0.0143884892086331 0.788785442234448 0.723901251824768 0.844263277121333 GO:0016278 lysine N-methyltransferase activity 1/340 70/18639 0.0142857142857143 0.783151260504202 0.725030660238292 0.844263277121333 GO:0022804 active transmembrane transporter activity 7/340 457/18639 0.0153172866520788 0.839702664435577 0.731589473137324 0.8504879281414 GO:0004521 RNA endonuclease activity 1/340 73/18639 0.0136986301369863 0.750966962127317 0.73986071142496 0.858679401835922 GO:0019955 cytokine binding 2/340 144/18639 0.0138888888888889 0.761397058823529 0.741768574883134 0.859470695856325 GO:0044183 protein folding chaperone 1/340 75/18639 0.0133333333333333 0.730941176470588 0.749301606216666 0.866766379468454 GO:0051536 iron-sulfur cluster binding 1/340 76/18639 0.0131578947368421 0.721323529411765 0.753893151890354 0.869209045189371 GO:0098631 cell adhesion mediator activity 1/340 76/18639 0.0131578947368421 0.721323529411765 0.753893151890354 0.869209045189371 GO:0051540 metal cluster binding 1/340 77/18639 0.012987012987013 0.711955691367456 0.758400846140059 0.872731760312124 GO:0019199 transmembrane receptor protein kinase activity 1/340 78/18639 0.0128205128205128 0.702828054298642 0.762826215836879 0.872731760312124 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 5/340 349/18639 0.0143266475644699 0.785395246923985 0.766161100031139 0.872731760312124 GO:0000049 tRNA binding 1/340 80/18639 0.0125 0.685257352941177 0.7714359509461 0.872731760312124 GO:0003774 cytoskeletal motor activity 2/340 153/18639 0.0130718954248366 0.716608996539792 0.771443965506535 0.872731760312124 GO:0005506 iron ion binding 2/340 154/18639 0.012987012987013 0.711955691367456 0.774551291951136 0.872731760312124 GO:0015101 organic cation transmembrane transporter activity 1/340 81/18639 0.0123456790123457 0.676797385620915 0.775623233487095 0.872731760312124 GO:0033192 calmodulin-dependent protein phosphatase activity 1/340 81/18639 0.0123456790123457 0.676797385620915 0.775623233487095 0.872731760312124 GO:0140791 histone H2AXS140 phosphatase activity 1/340 81/18639 0.0123456790123457 0.676797385620915 0.775623233487095 0.872731760312124 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/340 81/18639 0.0123456790123457 0.676797385620915 0.775623233487095 0.872731760312124 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/340 81/18639 0.0123456790123457 0.676797385620915 0.775623233487095 0.872731760312124 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/340 81/18639 0.0123456790123457 0.676797385620915 0.775623233487095 0.872731760312124 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/340 81/18639 0.0123456790123457 0.676797385620915 0.775623233487095 0.872731760312124 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/340 81/18639 0.0123456790123457 0.676797385620915 0.775623233487095 0.872731760312124 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/340 81/18639 0.0123456790123457 0.676797385620915 0.775623233487095 0.872731760312124 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/340 82/18639 0.0121951219512195 0.668543758967001 0.779734026709123 0.874549684356952 GO:0033549 MAP kinase phosphatase activity 1/340 82/18639 0.0121951219512195 0.668543758967001 0.779734026709123 0.874549684356952 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 7/340 484/18639 0.0144628099173554 0.792859747204667 0.783254219597053 0.874876713987152 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/340 83/18639 0.0120481927710843 0.660489014883062 0.783769723800188 0.874876713987152 GO:0008135 translation factor activity, RNA binding 1/340 83/18639 0.0120481927710843 0.660489014883062 0.783769723800188 0.874876713987152 GO:0004860 protein kinase inhibitor activity 1/340 84/18639 0.0119047619047619 0.652626050420168 0.787731692646272 0.875118726695779 GO:0017018 myosin phosphatase activity 1/340 84/18639 0.0119047619047619 0.652626050420168 0.787731692646272 0.875118726695779 GO:0180051 translation factor activity 1/340 84/18639 0.0119047619047619 0.652626050420168 0.787731692646272 0.875118726695779 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/340 229/18639 0.0131004366812227 0.718173645003853 0.791203403800158 0.87755847377652 GO:0015079 potassium ion transmembrane transporter activity 2/340 160/18639 0.0125 0.685257352941177 0.792431546220452 0.87755847377652 GO:0001216 DNA-binding transcription activator activity 7/340 491/18639 0.0142566191446029 0.781556247753684 0.795369310974972 0.879422534689993 GO:0008083 growth factor activity 2/340 162/18639 0.0123456790123457 0.676797385620915 0.798108118271635 0.880866612522397 GO:0008081 phosphoric diester hydrolase activity 1/340 87/18639 0.0114942528735632 0.630121703853955 0.799188538608052 0.880866612522397 GO:0003712 transcription coregulator activity 7/340 495/18639 0.0141414141414141 0.77524064171123 0.802059871784065 0.881971488849298 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/340 88/18639 0.0113636363636364 0.622961229946524 0.802868783157064 0.881971488849298 GO:0003727 single-stranded RNA binding 1/340 89/18639 0.0112359550561798 0.615961665565102 0.806481775110414 0.881971488849298 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/340 89/18639 0.0112359550561798 0.615961665565102 0.806481775110414 0.881971488849298 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/340 89/18639 0.0112359550561798 0.615961665565102 0.806481775110414 0.881971488849298 GO:0140793 histone H2AXY142 phosphatase activity 1/340 90/18639 0.0111111111111111 0.609117647058824 0.81002873987928 0.884470633419587 GO:0051213 dioxygenase activity 1/340 93/18639 0.010752688172043 0.589468690702087 0.820285393652479 0.893689441254109 GO:0005539 glycosaminoglycan binding 3/340 242/18639 0.012396694214876 0.679594069032572 0.821021398242006 0.893689441254109 GO:0016410 N-acyltransferase activity 1/340 94/18639 0.0106382978723404 0.58319774718398 0.823580064533432 0.895084690291374 GO:0004867 serine-type endopeptidase inhibitor activity 1/340 95/18639 0.0105263157894737 0.577058823529412 0.826814509292592 0.897208933458371 GO:0004896 cytokine receptor activity 1/340 96/18639 0.0104166666666667 0.571047794117647 0.82998982566665 0.899262546819662 GO:0004721 phosphoprotein phosphatase activity 2/340 175/18639 0.0114285714285714 0.626521008403361 0.831762994340091 0.899792992333957 GO:0030594 neurotransmitter receptor activity 1/340 97/18639 0.0103092783505155 0.56516070345664 0.833107091442055 0.899858353005979 GO:0004725 protein tyrosine phosphatase activity 1/340 98/18639 0.0102040816326531 0.559393757503001 0.83616736481654 0.900389128627334 GO:0005249 voltage-gated potassium channel activity 1/340 98/18639 0.0102040816326531 0.559393757503001 0.83616736481654 0.900389128627334 GO:0015171 amino acid transmembrane transporter activity 1/340 102/18639 0.00980392156862745 0.537456747404844 0.847859032355321 0.911578499510858 GO:0004722 protein serine/threonine phosphatase activity 1/340 103/18639 0.00970873786407767 0.532238720731011 0.8506495555791 0.913178159970825 GO:0004620 phospholipase activity 1/340 109/18639 0.00917431192660551 0.502941176470588 0.866352944370698 0.928613782880519 GO:0004222 metalloendopeptidase activity 1/340 110/18639 0.00909090909090909 0.498368983957219 0.868805183923529 0.929820509817395 GO:0005261 monoatomic cation channel activity 4/340 341/18639 0.0117302052785924 0.643056753493186 0.87209660550161 0.931920305574129 GO:0016887 ATP hydrolysis activity 5/340 417/18639 0.0119904076738609 0.65732120186204 0.880607425362339 0.939582656284627 GO:0015294 solute:monoatomic cation symporter activity 1/340 116/18639 0.00862068965517241 0.472591277890467 0.882604580624991 0.940039611345799 GO:0140297 DNA-binding transcription factor binding 6/340 488/18639 0.0122950819672131 0.67402362584378 0.883717694546193 0.940039611345799 GO:0003714 transcription corepressor activity 2/340 204/18639 0.00980392156862745 0.537456747404844 0.88930061192612 0.944545043879106 GO:0015108 chloride transmembrane transporter activity 1/340 121/18639 0.00826446280991736 0.453062712688381 0.89299161077973 0.947030437453238 GO:0008528 G protein-coupled peptide receptor activity 1/340 122/18639 0.00819672131147541 0.449349083895853 0.894956339818227 0.947434227379362 GO:0004518 nuclease activity 2/340 209/18639 0.00956937799043062 0.524598930481283 0.897157022126452 0.947434227379362 GO:0015291 secondary active transmembrane transporter activity 3/340 287/18639 0.0104529616724739 0.573037507686001 0.89778116336743 0.947434227379362 GO:0005267 potassium channel activity 1/340 124/18639 0.00806451612903226 0.442101518026565 0.898778546658025 0.947434227379362 GO:0004519 endonuclease activity 1/340 127/18639 0.0078740157480315 0.431658175081056 0.904253399864587 0.951774224181795 GO:0001653 peptide receptor activity 1/340 128/18639 0.0078125 0.428285845588235 0.90601192644443 0.95219544293485 GO:0005179 hormone activity 1/340 132/18639 0.00757575757575758 0.415307486631016 0.912729813495688 0.957819759371972 GO:0046873 metal ion transmembrane transporter activity 5/340 450/18639 0.0111111111111111 0.609117647058824 0.916285092060961 0.959901350271862 GO:0015297 antiporter activity 1/340 135/18639 0.00740740740740741 0.406078431372549 0.91745207515285 0.959901350271862 GO:0099094 ligand-gated monoatomic cation channel activity 1/340 136/18639 0.00735294117647059 0.403092560553633 0.918968844199976 0.960055379708172 GO:0070851 growth factor receptor binding 1/340 139/18639 0.00719424460431655 0.394392721117224 0.923354437174449 0.963201578064417 GO:0140098 catalytic activity, acting on RNA 4/340 387/18639 0.0103359173126615 0.566621067031464 0.925250349036177 0.963745162963388 GO:0020037 heme binding 1/340 142/18639 0.00704225352112676 0.38606048053024 0.927503332028985 0.964613302878332 GO:0022843 voltage-gated monoatomic cation channel activity 1/340 143/18639 0.00699300699300699 0.383360756890169 0.928835919319364 0.964613302878332 GO:0015293 symporter activity 1/340 146/18639 0.00684931506849315 0.375483481063658 0.932688914219514 0.967181847437692 GO:0008509 monoatomic anion transmembrane transporter activity 1/340 149/18639 0.00671140939597315 0.367923410975128 0.936333878986109 0.969527399068335 GO:0046906 tetrapyrrole binding 1/340 152/18639 0.00657894736842105 0.360661764705882 0.939782014199258 0.971662525005427 GO:0042393 histone binding 2/340 247/18639 0.00809716599190283 0.443891402714932 0.941911081188818 0.97242955510068 GO:0140104 molecular carrier activity 2/340 249/18639 0.00803212851405622 0.440326009922041 0.943660887802772 0.972803356396681 GO:0015103 inorganic anion transmembrane transporter activity 1/340 165/18639 0.00606060606060606 0.332245989304813 0.952696742143321 0.979501209562168 GO:0003730 mRNA 3'-UTR binding 2/340 262/18639 0.00763358778625954 0.418477772788505 0.953870912040045 0.979501209562168 GO:0008201 heparin binding 1/340 172/18639 0.00581395348837209 0.318724350205198 0.958465355385665 0.979501209562168 GO:0005244 voltage-gated monoatomic ion channel activity 1/340 173/18639 0.00578034682080925 0.316882012920775 0.959230058865867 0.979501209562168 GO:0140030 modification-dependent protein binding 1/340 173/18639 0.00578034682080925 0.316882012920775 0.959230058865867 0.979501209562168 GO:0003823 antigen binding 1/340 174/18639 0.00574712643678161 0.315060851926978 0.959980723871044 0.979501209562168 GO:0022832 voltage-gated channel activity 1/340 175/18639 0.00571428571428571 0.313260504201681 0.960717607374096 0.979501209562168 GO:0043021 ribonucleoprotein complex binding 1/340 177/18639 0.00564971751412429 0.309720837487537 0.962151034399763 0.979501209562168 GO:0005216 monoatomic ion channel activity 4/340 448/18639 0.00892857142857143 0.489469537815126 0.965060375257618 0.979501209562168 GO:0015276 ligand-gated monoatomic ion channel activity 1/340 186/18639 0.00537634408602151 0.294734345351044 0.967982712449311 0.979501209562168 GO:0022834 ligand-gated channel activity 1/340 188/18639 0.00531914893617021 0.29159887359199 0.969151723465031 0.979501209562168 GO:0046943 carboxylic acid transmembrane transporter activity 1/340 188/18639 0.00531914893617021 0.29159887359199 0.969151723465031 0.979501209562168 GO:0140597 protein carrier chaperone 1/340 188/18639 0.00531914893617021 0.29159887359199 0.969151723465031 0.979501209562168 GO:0005342 organic acid transmembrane transporter activity 1/340 189/18639 0.00529100529100529 0.290056022408964 0.969720170379664 0.979501209562168 GO:0016829 lyase activity 1/340 200/18639 0.005 0.274102941176471 0.975324157478508 0.983744222147387 GO:0008094 ATP-dependent activity, acting on DNA 1/340 210/18639 0.00476190476190476 0.261050420168067 0.979515553685218 0.986552303352497 GO:0045182 translation regulator activity 2/340 356/18639 0.00561797752808989 0.307980832782551 0.989648022290494 0.995327494441372 GO:0008514 organic anion transmembrane transporter activity 1/340 269/18639 0.00371747211895911 0.203794008309644 0.993184161871467 0.99675078526712 GO:1901681 sulfur compound binding 1/340 275/18639 0.00363636363636364 0.199347593582888 0.993906988447528 0.99675078526712 GO:0022836 gated channel activity 1/340 318/18639 0.00314465408805031 0.172391786903441 0.997274563914065 0.998054947301531 GO:0140097 catalytic activity, acting on DNA 1/340 336/18639 0.00297619047619048 0.163156512605042 0.998054947301531 0.998054947301531