ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 41/1050 175/18639 0.234285714285714 4.15890612244898 3.2632624049374e-15 3.39052963872995e-12 GO:0023023 MHC protein complex binding 18/1050 37/18639 0.486486486486487 8.63583011583012 1.80484815218023e-13 9.37618615057629e-11 GO:0023026 MHC class II protein complex binding 15/1050 27/18639 0.555555555555556 9.86190476190476 1.52012654214651e-12 5.26470492430074e-10 GO:0140375 immune receptor activity 33/1050 156/18639 0.211538461538462 3.75510989010989 3.20598610248471e-11 8.32754890120404e-09 GO:0042605 peptide antigen binding 15/1050 45/18639 0.333333333333333 5.91714285714286 1.15528495541882e-08 2.4006821373603e-06 GO:0005201 extracellular matrix structural constituent 30/1050 168/18639 0.178571428571429 3.16989795918367 1.68985728983199e-08 2.92626954022572e-06 GO:0032395 MHC class II receptor activity 7/1050 10/18639 0.7 12.426 1.82369493680503e-07 2.7068843419149e-05 GO:0005518 collagen binding 17/1050 72/18639 0.236111111111111 4.19130952380952 3.64306338532604e-07 4.73142857169219e-05 GO:0044183 protein folding chaperone 17/1050 75/18639 0.226666666666667 4.02365714285714 6.79335552862191e-07 7.84255154915352e-05 GO:0050840 extracellular matrix binding 15/1050 67/18639 0.223880597014925 3.97420042643923 3.60361586973294e-06 0.000374415688865253 GO:0042277 peptide binding 33/1050 249/18639 0.132530120481928 2.35259896729776 4.28225149934092e-06 0.000404478118892292 GO:0051787 misfolded protein binding 7/1050 17/18639 0.411764705882353 7.30941176470588 2.08310768304107e-05 0.00180362406889973 GO:0003924 GTPase activity 38/1050 331/18639 0.114803625377644 2.03792835563228 2.48154836729284e-05 0.00198332981047482 GO:0035325 Toll-like receptor binding 6/1050 13/18639 0.461538461538462 8.19296703296703 3.83794945927585e-05 0.00284830677727687 GO:0031625 ubiquitin protein ligase binding 35/1050 302/18639 0.115894039735099 2.05728476821192 4.20932392883757e-05 0.00285625254856982 GO:0003823 antigen binding 24/1050 174/18639 0.137931034482759 2.44847290640394 4.39846398239818e-05 0.00285625254856982 GO:0019955 cytokine binding 21/1050 144/18639 0.145833333333333 2.58875 5.70562107912374e-05 0.00348714135365268 GO:0019763 immunoglobulin receptor activity 6/1050 14/18639 0.428571428571429 7.60775510204082 6.39618975249466e-05 0.00369202286268997 GO:0042287 MHC protein binding 10/1050 41/18639 0.24390243902439 4.32961672473868 6.96824547196351e-05 0.00371534666866357 GO:0042288 MHC class I protein binding 7/1050 20/18639 0.35 6.213 7.1517741456469e-05 0.00371534666866357 GO:0002020 protease binding 20/1050 136/18639 0.147058823529412 2.61050420168067 7.53936899976406e-05 0.00373019256702613 GO:0005044 scavenger receptor activity 8/1050 27/18639 0.296296296296296 5.25968253968254 8.38026497879205e-05 0.00395777059680225 GO:0055106 ubiquitin-protein transferase regulator activity 9/1050 36/18639 0.25 4.43785714285714 0.000130553478170816 0.00589761147041206 GO:0044389 ubiquitin-like protein ligase binding 35/1050 322/18639 0.108695652173913 1.92950310559006 0.000153358338396961 0.00663913806643509 GO:0003925 G protein activity 11/1050 54/18639 0.203703703703704 3.61603174603175 0.000176038490007012 0.00731615964469143 GO:0019864 IgG binding 5/1050 11/18639 0.454545454545455 8.06883116883117 0.00019511509711141 0.00750831799625017 GO:1990948 ubiquitin ligase inhibitor activity 5/1050 11/18639 0.454545454545455 8.06883116883117 0.00019511509711141 0.00750831799625017 GO:0019843 rRNA binding 12/1050 65/18639 0.184615384615385 3.27718681318681 0.000241597826310637 0.00896500505488399 GO:0048027 mRNA 5'-UTR binding 7/1050 24/18639 0.291666666666667 5.1775 0.000261835584097894 0.00906823906259041 GO:0050431 transforming growth factor beta binding 7/1050 24/18639 0.291666666666667 5.1775 0.000261835584097894 0.00906823906259041 GO:0005178 integrin binding 21/1050 161/18639 0.130434782608696 2.31540372670807 0.000284077717664507 0.00952118544043298 GO:0035259 nuclear glucocorticoid receptor binding 5/1050 12/18639 0.416666666666667 7.39642857142857 0.00031898182776313 0.0103569412201841 GO:0019956 chemokine binding 8/1050 33/18639 0.242424242424242 4.30337662337662 0.00038769470119079 0.0122065089253706 GO:0051082 unfolded protein binding 17/1050 121/18639 0.140495867768595 2.49400236127509 0.000440423641800178 0.013381164447756 GO:0019865 immunoglobulin binding 7/1050 26/18639 0.269230769230769 4.77923076923077 0.000450761073793513 0.013381164447756 GO:0019838 growth factor binding 18/1050 136/18639 0.132352941176471 2.3494537815126 0.000630554514636938 0.0181985039085494 GO:0008009 chemokine activity 9/1050 45/18639 0.2 3.55028571428571 0.000778769593771318 0.021868692106173 GO:0016798 hydrolase activity, acting on glycosyl bonds 17/1050 130/18639 0.130769230769231 2.32134065934066 0.00101076313615597 0.027636392064896 GO:0055105 ubiquitin-protein transferase inhibitor activity 5/1050 15/18639 0.333333333333333 5.91714285714286 0.00104943803687494 0.0279581056490528 GO:0001968 fibronectin binding 7/1050 30/18639 0.233333333333333 4.142 0.00114523645135868 0.0290156334013475 GO:0035925 mRNA 3'-UTR AU-rich region binding 7/1050 30/18639 0.233333333333333 4.142 0.00114523645135868 0.0290156334013475 GO:0030246 carbohydrate binding 29/1050 280/18639 0.103571428571429 1.83854081632653 0.00117291299601212 0.0290156334013475 GO:0038187 pattern recognition receptor activity 9/1050 48/18639 0.1875 3.32839285714286 0.00126674947301899 0.0306082023829473 GO:0004090 carbonyl reductase (NADPH) activity 4/1050 10/18639 0.4 7.10057142857143 0.00159888062901318 0.0377553857623793 GO:0030169 low-density lipoprotein particle binding 5/1050 17/18639 0.294117647058824 5.22100840336134 0.00196796007821691 0.0454380115837193 GO:0009055 electron transfer activity 15/1050 116/18639 0.129310344827586 2.29544334975369 0.00218385658726678 0.0489151494829034 GO:0001540 amyloid-beta binding 12/1050 83/18639 0.144578313253012 2.56647160068847 0.00229360986976177 0.0489151494829034 GO:0019206 nucleoside kinase activity 4/1050 11/18639 0.363636363636364 6.45506493506493 0.00240103236152846 0.0489151494829034 GO:0048407 platelet-derived growth factor binding 4/1050 11/18639 0.363636363636364 6.45506493506493 0.00240103236152846 0.0489151494829034 GO:0050786 RAGE receptor binding 4/1050 11/18639 0.363636363636364 6.45506493506493 0.00240103236152846 0.0489151494829034 GO:0097493 structural molecule activity conferring elasticity 4/1050 11/18639 0.363636363636364 6.45506493506493 0.00240103236152846 0.0489151494829034 GO:0140297 DNA-binding transcription factor binding 43/1050 488/18639 0.0881147540983607 1.56416276346604 0.00249403367342665 0.0498327112825055 GO:0032393 MHC class I receptor activity 5/1050 18/18639 0.277777777777778 4.93095238095238 0.00259971563178438 0.050964236630641 GO:0019003 GDP binding 11/1050 75/18639 0.146666666666667 2.60354285714286 0.00306689543007098 0.0590093398489582 GO:0038024 cargo receptor activity 10/1050 65/18639 0.153846153846154 2.73098901098901 0.00327206463297536 0.0605016202308104 GO:0033218 amide binding 25/1050 247/18639 0.101214574898785 1.7967032967033 0.00336129868243488 0.0605016202308104 GO:0005520 insulin-like growth factor binding 5/1050 19/18639 0.263157894736842 4.67142857142857 0.00336638936025927 0.0605016202308104 GO:0140313 molecular sequestering activity 9/1050 55/18639 0.163636363636364 2.90477922077922 0.00337737629777382 0.0605016202308104 GO:0051087 protein-folding chaperone binding 16/1050 134/18639 0.119402985074627 2.11957356076759 0.00358862037556726 0.063196213054481 GO:0031994 insulin-like growth factor I binding 4/1050 13/18639 0.307692307692308 5.46197802197802 0.0047521462250407 0.0796367730293112 GO:0032396 inhibitory MHC class I receptor activity 4/1050 13/18639 0.307692307692308 5.46197802197802 0.0047521462250407 0.0796367730293112 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 4/1050 13/18639 0.307692307692308 5.46197802197802 0.0047521462250407 0.0796367730293112 GO:0043236 laminin binding 6/1050 29/18639 0.206896551724138 3.67270935960591 0.00489552866881205 0.0807373696332653 GO:0043021 ribonucleoprotein complex binding 19/1050 177/18639 0.107344632768362 1.9055205811138 0.00526953951854581 0.0855476806213921 GO:0008106 alcohol dehydrogenase (NADP+) activity 6/1050 30/18639 0.2 3.55028571428571 0.0058331017231754 0.093239887544296 GO:0035591 signaling adaptor activity 15/1050 129/18639 0.116279069767442 2.0641196013289 0.00603481540218941 0.0950026242859817 GO:0140662 ATP-dependent protein folding chaperone 7/1050 40/18639 0.175 3.1065 0.00642642960037094 0.099657617235603 GO:0030021 extracellular matrix structural constituent conferring compression resistance 5/1050 22/18639 0.227272727272727 4.03441558441558 0.0066254186949482 0.0997653626674085 GO:0061133 endopeptidase activator activity 5/1050 22/18639 0.227272727272727 4.03441558441558 0.0066254186949482 0.0997653626674085 GO:0042379 chemokine receptor binding 10/1050 72/18639 0.138888888888889 2.46547619047619 0.00688257267369286 0.10163628874191 GO:0031072 heat shock protein binding 15/1050 131/18639 0.114503816793893 2.03260632497274 0.00694530943279658 0.10163628874191 GO:0008137 NADH dehydrogenase (ubiquinone) activity 7/1050 41/18639 0.170731707317073 3.03073170731707 0.00738120413137613 0.106514876284719 GO:0004896 cytokine receptor activity 12/1050 96/18639 0.125 2.21892857142857 0.00760029962620346 0.108174127556512 GO:0008142 oxysterol binding 4/1050 16/18639 0.25 4.43785714285714 0.0105687459819923 0.146412361003867 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 4/1050 16/18639 0.25 4.43785714285714 0.0105687459819923 0.146412361003867 GO:0003954 NADH dehydrogenase activity 7/1050 44/18639 0.159090909090909 2.82409090909091 0.0108748836929044 0.148671107327995 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 11/1050 91/18639 0.120879120879121 2.14577708006279 0.013152842967435 0.17568840573134 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 9/1050 68/18639 0.132352941176471 2.3494537815126 0.0136819626928397 0.17568840573134 GO:0032934 sterol binding 9/1050 68/18639 0.132352941176471 2.3494537815126 0.0136819626928397 0.17568840573134 GO:0030247 polysaccharide binding 5/1050 26/18639 0.192307692307692 3.41373626373626 0.0137398387580691 0.17568840573134 GO:0004180 carboxypeptidase activity 7/1050 46/18639 0.152173913043478 2.70130434782609 0.0137868965913677 0.17568840573134 GO:0016504 peptidase activator activity 8/1050 57/18639 0.140350877192982 2.49142857142857 0.0140259500346595 0.17568840573134 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 30/1050 349/18639 0.0859598853868195 1.52591076545231 0.014290349646068 0.17568840573134 GO:0005525 GTP binding 32/1050 378/18639 0.0846560846560847 1.5027664399093 0.0143343129144266 0.17568840573134 GO:0004033 aldo-keto reductase (NADPH) activity 6/1050 36/18639 0.166666666666667 2.95857142857143 0.0143729687075687 0.17568840573134 GO:0001618 virus receptor activity 10/1050 81/18639 0.123456790123457 2.19153439153439 0.015344031571579 0.177059318594669 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 8/1050 58/18639 0.137931034482759 2.44847290640394 0.0154913958291388 0.177059318594669 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 3/1050 10/18639 0.3 5.32542857142857 0.0158713587809018 0.177059318594669 GO:0031996 thioesterase binding 3/1050 10/18639 0.3 5.32542857142857 0.0158713587809018 0.177059318594669 GO:0071723 lipopeptide binding 3/1050 10/18639 0.3 5.32542857142857 0.0158713587809018 0.177059318594669 GO:1905394 retromer complex binding 3/1050 10/18639 0.3 5.32542857142857 0.0158713587809018 0.177059318594669 GO:0001671 ATPase activator activity 5/1050 27/18639 0.185185185185185 3.28730158730159 0.0160993212655017 0.177059318594669 GO:0004364 glutathione transferase activity 5/1050 27/18639 0.185185185185185 3.28730158730159 0.0160993212655017 0.177059318594669 GO:0017075 syntaxin-1 binding 4/1050 18/18639 0.222222222222222 3.9447619047619 0.0162481205055233 0.177059318594669 GO:0097110 scaffold protein binding 9/1050 70/18639 0.128571428571429 2.28232653061224 0.0163507678997267 0.177059318594669 GO:0043394 proteoglycan binding 6/1050 37/18639 0.162162162162162 2.87861003861004 0.0163596675506143 0.177059318594669 GO:0140272 exogenous protein binding 10/1050 82/18639 0.121951219512195 2.16480836236934 0.0166224807561409 0.178049046449798 GO:0001664 G protein-coupled receptor binding 26/1050 297/18639 0.0875420875420875 1.55399711399711 0.0174466742257745 0.184970352250813 GO:0019001 guanyl nucleotide binding 33/1050 400/18639 0.0825 1.46449285714286 0.0183913502740705 0.191086129347593 GO:0032561 guanyl ribonucleotide binding 33/1050 400/18639 0.0825 1.46449285714286 0.0183913502740705 0.191086129347593 GO:0060590 ATPase regulator activity 7/1050 49/18639 0.142857142857143 2.53591836734694 0.0191413695519704 0.196909732321755 GO:0003756 protein disulfide isomerase activity 4/1050 19/18639 0.210526315789474 3.73714285714286 0.0196832488109271 0.198552383636439 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 4/1050 19/18639 0.210526315789474 3.73714285714286 0.0196832488109271 0.198552383636439 GO:0019905 syntaxin binding 8/1050 61/18639 0.131147540983607 2.32805620608899 0.0205496540302469 0.205082242495333 GO:0005225 volume-sensitive anion channel activity 3/1050 11/18639 0.272727272727273 4.8412987012987 0.0209227311881668 0.205082242495333 GO:0042608 T cell receptor binding 3/1050 11/18639 0.272727272727273 4.8412987012987 0.0209227311881668 0.205082242495333 GO:0051861 glycolipid binding 5/1050 29/18639 0.172413793103448 3.06059113300493 0.0215924038283353 0.209668295118134 GO:0005126 cytokine receptor binding 24/1050 275/18639 0.0872727272727273 1.54921558441558 0.022451416366981 0.215990940789752 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 6/1050 40/18639 0.15 2.66271428571429 0.0234358659051275 0.223393253903004 GO:0043022 ribosome binding 12/1050 112/18639 0.107142857142857 1.9019387755102 0.0238382188099648 0.223775638231168 GO:0005125 cytokine activity 21/1050 234/18639 0.0897435897435897 1.59307692307692 0.0239067332470257 0.223775638231168 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 7/1050 52/18639 0.134615384615385 2.38961538461538 0.0258032583267933 0.239058461094032 GO:0016651 oxidoreductase activity, acting on NAD(P)H 10/1050 88/18639 0.113636363636364 2.01720779220779 0.0259996208889563 0.239058461094032 GO:0004875 complement receptor activity 3/1050 12/18639 0.25 4.43785714285714 0.026749622374752 0.240396986619054 GO:0070008 serine-type exopeptidase activity 3/1050 12/18639 0.25 4.43785714285714 0.026749622374752 0.240396986619054 GO:0042826 histone deacetylase binding 13/1050 127/18639 0.102362204724409 1.8170753655793 0.0268393170816268 0.240396986619054 GO:0051015 actin filament binding 19/1050 209/18639 0.0909090909090909 1.61376623376623 0.0272348965611707 0.240773783138621 GO:0003779 actin binding 35/1050 443/18639 0.0790067720090293 1.40248306997743 0.0275926661154247 0.240773783138621 GO:0001846 opsonin binding 4/1050 21/18639 0.19047619047619 3.38122448979592 0.027808329140168 0.240773783138621 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 4/1050 21/18639 0.19047619047619 3.38122448979592 0.027808329140168 0.240773783138621 GO:0035401 histone H3Y41 kinase activity 12/1050 115/18639 0.104347826086957 1.85232298136646 0.0286021930295624 0.243587529161601 GO:0140801 histone H2AXY142 kinase activity 12/1050 115/18639 0.104347826086957 1.85232298136646 0.0286021930295624 0.243587529161601 GO:0004857 enzyme inhibitor activity 33/1050 416/18639 0.0793269230769231 1.40816620879121 0.0301682635434441 0.254835982289744 GO:0071813 lipoprotein particle binding 5/1050 32/18639 0.15625 2.77366071428571 0.0318965384196087 0.264383931727795 GO:0071814 protein-lipid complex binding 5/1050 32/18639 0.15625 2.77366071428571 0.0318965384196087 0.264383931727795 GO:1990782 protein tyrosine kinase binding 12/1050 117/18639 0.102564102564103 1.82065934065934 0.032138774902774 0.264383931727795 GO:0048156 tau protein binding 6/1050 43/18639 0.13953488372093 2.47694352159468 0.0323164189888642 0.264383931727795 GO:0035673 oligopeptide transmembrane transporter activity 3/1050 13/18639 0.230769230769231 4.09648351648352 0.0333488652196654 0.268600550102577 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 3/1050 13/18639 0.230769230769231 4.09648351648352 0.0333488652196654 0.268600550102577 GO:0019205 nucleobase-containing compound kinase activity 6/1050 44/18639 0.136363636363636 2.42064935064935 0.0357019245619105 0.279030469819141 GO:0030020 extracellular matrix structural constituent conferring tensile strength 6/1050 44/18639 0.136363636363636 2.42064935064935 0.0357019245619105 0.279030469819141 GO:0000149 SNARE binding 11/1050 106/18639 0.10377358490566 1.84212938005391 0.0363666798008664 0.279030469819141 GO:0004602 glutathione peroxidase activity 4/1050 23/18639 0.173913043478261 3.0872049689441 0.0376599744225182 0.279030469819141 GO:0045296 cadherin binding 27/1050 334/18639 0.0808383233532934 1.43499572284003 0.0381097254272408 0.279030469819141 GO:0033192 calmodulin-dependent protein phosphatase activity 9/1050 81/18639 0.111111111111111 1.97238095238095 0.0381350593978037 0.279030469819141 GO:0140791 histone H2AXS140 phosphatase activity 9/1050 81/18639 0.111111111111111 1.97238095238095 0.0381350593978037 0.279030469819141 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 9/1050 81/18639 0.111111111111111 1.97238095238095 0.0381350593978037 0.279030469819141 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 9/1050 81/18639 0.111111111111111 1.97238095238095 0.0381350593978037 0.279030469819141 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 9/1050 81/18639 0.111111111111111 1.97238095238095 0.0381350593978037 0.279030469819141 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 9/1050 81/18639 0.111111111111111 1.97238095238095 0.0381350593978037 0.279030469819141 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 9/1050 81/18639 0.111111111111111 1.97238095238095 0.0381350593978037 0.279030469819141 GO:1990439 MAP kinase serine/threonine phosphatase activity 9/1050 81/18639 0.111111111111111 1.97238095238095 0.0381350593978037 0.279030469819141 GO:0004715 non-membrane spanning protein tyrosine kinase activity 6/1050 45/18639 0.133333333333333 2.36685714285714 0.0393070243140517 0.282899587979834 GO:0046915 transition metal ion transmembrane transporter activity 6/1050 45/18639 0.133333333333333 2.36685714285714 0.0393070243140517 0.282899587979834 GO:0004540 RNA nuclease activity 12/1050 121/18639 0.0991735537190083 1.76047225501771 0.0401312596162768 0.282899587979834 GO:0015035 protein-disulfide reductase activity 5/1050 34/18639 0.147058823529412 2.61050420168067 0.0402182873329695 0.282899587979834 GO:0005161 platelet-derived growth factor receptor binding 3/1050 14/18639 0.214285714285714 3.80387755102041 0.040709569072635 0.282899587979834 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 9/1050 82/18639 0.109756097560976 1.9483275261324 0.0407872951207484 0.282899587979834 GO:0033549 MAP kinase phosphatase activity 9/1050 82/18639 0.109756097560976 1.9483275261324 0.0407872951207484 0.282899587979834 GO:0005496 steroid binding 11/1050 108/18639 0.101851851851852 1.80801587301587 0.0408420964359721 0.282899587979834 GO:0140789 histone phosphatase activity 13/1050 136/18639 0.0955882352941176 1.69682773109244 0.0432755584017862 0.297765032544684 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 9/1050 83/18639 0.108433734939759 1.92485370051635 0.0435613907091357 0.297765032544684 GO:0017018 myosin phosphatase activity 9/1050 84/18639 0.107142857142857 1.9019387755102 0.0464591614867029 0.314034275509262 GO:0070888 E-box binding 7/1050 59/18639 0.11864406779661 2.10610169491525 0.0470774063081562 0.314034275509262 GO:0004518 nuclease activity 18/1050 209/18639 0.0861244019138756 1.52883116883117 0.0485314275810466 0.314034275509262 GO:0004559 alpha-mannosidase activity 3/1050 15/18639 0.2 3.55028571428571 0.0488143132900175 0.314034275509262 GO:0005041 low-density lipoprotein particle receptor activity 3/1050 15/18639 0.2 3.55028571428571 0.0488143132900175 0.314034275509262 GO:0016846 carbon-sulfur lyase activity 3/1050 15/18639 0.2 3.55028571428571 0.0488143132900175 0.314034275509262 GO:0140776 protein-containing complex destabilizing activity 3/1050 15/18639 0.2 3.55028571428571 0.0488143132900175 0.314034275509262 GO:0004725 protein tyrosine phosphatase activity 10/1050 98/18639 0.102040816326531 1.81137026239067 0.0491500102433747 0.314034275509262 GO:0001848 complement binding 4/1050 25/18639 0.16 2.84022857142857 0.0492662049162751 0.314034275509262 GO:0004709 MAP kinase kinase kinase activity 4/1050 25/18639 0.16 2.84022857142857 0.0492662049162751 0.314034275509262 GO:0005537 D-mannose binding 4/1050 25/18639 0.16 2.84022857142857 0.0492662049162751 0.314034275509262 GO:0016247 channel regulator activity 15/1050 168/18639 0.0892857142857143 1.58494897959184 0.0523409026632035 0.33037182501973 GO:0004713 protein tyrosine kinase activity 13/1050 140/18639 0.0928571428571429 1.64834693877551 0.0524652080156453 0.33037182501973 GO:0061134 peptidase regulator activity 19/1050 226/18639 0.084070796460177 1.49237673830594 0.0532381739893712 0.333219655270823 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 4/1050 26/18639 0.153846153846154 2.73098901098901 0.0557255442177671 0.338351309390431 GO:0008157 protein phosphatase 1 binding 4/1050 26/18639 0.153846153846154 2.73098901098901 0.0557255442177671 0.338351309390431 GO:0043548 phosphatidylinositol 3-kinase binding 4/1050 26/18639 0.153846153846154 2.73098901098901 0.0557255442177671 0.338351309390431 GO:0001222 transcription corepressor binding 6/1050 49/18639 0.122448979591837 2.1736443148688 0.0559812999928019 0.338351309390431 GO:0019207 kinase regulator activity 23/1050 287/18639 0.0801393728222996 1.42258835241414 0.0566666406998702 0.338351309390431 GO:0141108 transporter regulator activity 15/1050 170/18639 0.0882352941176471 1.5663025210084 0.05690549232531 0.338351309390431 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 12/1050 128/18639 0.09375 1.66419642857143 0.0572842866857019 0.338351309390431 GO:0015923 mannosidase activity 3/1050 16/18639 0.1875 3.32839285714286 0.0576402134380234 0.338351309390431 GO:0016722 oxidoreductase activity, acting on metal ions 3/1050 16/18639 0.1875 3.32839285714286 0.0576402134380234 0.338351309390431 GO:0031435 mitogen-activated protein kinase kinase kinase binding 3/1050 16/18639 0.1875 3.32839285714286 0.0576402134380234 0.338351309390431 GO:0097027 ubiquitin-protein transferase activator activity 3/1050 16/18639 0.1875 3.32839285714286 0.0576402134380234 0.338351309390431 GO:0004197 cysteine-type endopeptidase activity 9/1050 88/18639 0.102272727272727 1.81548701298701 0.0593179561483966 0.343257685616119 GO:0001221 transcription coregulator binding 11/1050 115/18639 0.0956521739130435 1.69796273291925 0.0594671640143422 0.343257685616119 GO:0017124 SH3 domain binding 11/1050 115/18639 0.0956521739130435 1.69796273291925 0.0594671640143422 0.343257685616119 GO:0008238 exopeptidase activity 10/1050 102/18639 0.0980392156862745 1.74033613445378 0.0613851087582428 0.35237087292715 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 9/1050 89/18639 0.101123595505618 1.79508828250401 0.0628559301481375 0.355213200228081 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 9/1050 89/18639 0.101123595505618 1.79508828250401 0.0628559301481375 0.355213200228081 GO:0019903 protein phosphatase binding 13/1050 144/18639 0.0902777777777778 1.60255952380952 0.0629058987891886 0.355213200228081 GO:0017022 myosin binding 8/1050 76/18639 0.105263157894737 1.86857142857143 0.0635949705931142 0.357163105114842 GO:0030544 Hsp70 protein binding 6/1050 51/18639 0.117647058823529 2.08840336134454 0.0656952598483935 0.366975134314413 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 5/1050 39/18639 0.128205128205128 2.27582417582418 0.0662972038472329 0.367258456183947 GO:0140793 histone H2AXY142 phosphatase activity 9/1050 90/18639 0.1 1.77514285714286 0.0665251780412324 0.367258456183947 GO:0016805 dipeptidase activity 3/1050 17/18639 0.176470588235294 3.13260504201681 0.0671598716794513 0.367258456183947 GO:0036041 long-chain fatty acid binding 3/1050 17/18639 0.176470588235294 3.13260504201681 0.0671598716794513 0.367258456183947 GO:0099106 ion channel regulator activity 14/1050 160/18639 0.0875 1.55325 0.0678547465933476 0.368802449680293 GO:0141003 histone H2AX kinase activity 27/1050 354/18639 0.076271186440678 1.35392251815981 0.0681521369957808 0.368802449680293 GO:0022853 active monoatomic ion transmembrane transporter activity 11/1050 118/18639 0.0932203389830508 1.65479418886199 0.0689259243952481 0.371057178480118 GO:0046625 sphingolipid binding 4/1050 28/18639 0.142857142857143 2.53591836734694 0.0699342994202497 0.37454503658577 GO:0019902 phosphatase binding 16/1050 190/18639 0.0842105263157895 1.49485714285714 0.0707067003070072 0.376739803174259 GO:0015036 disulfide oxidoreductase activity 5/1050 40/18639 0.125 2.21892857142857 0.0724202521246765 0.383901234477239 GO:0140996 histone H3 kinase activity 27/1050 357/18639 0.0756302521008403 1.3425450180072 0.0737853234874638 0.389152036058248 GO:0003746 translation elongation factor activity 3/1050 18/18639 0.166666666666667 2.95857142857143 0.077342221914237 0.389845863868789 GO:0004706 JUN kinase kinase kinase activity 3/1050 18/18639 0.166666666666667 2.95857142857143 0.077342221914237 0.389845863868789 GO:0008409 5'-3' exonuclease activity 3/1050 18/18639 0.166666666666667 2.95857142857143 0.077342221914237 0.389845863868789 GO:0016854 racemase and epimerase activity 3/1050 18/18639 0.166666666666667 2.95857142857143 0.077342221914237 0.389845863868789 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 3/1050 18/18639 0.166666666666667 2.95857142857143 0.077342221914237 0.389845863868789 GO:0017128 phospholipid scramblase activity 3/1050 18/18639 0.166666666666667 2.95857142857143 0.077342221914237 0.389845863868789 GO:0030228 lipoprotein particle receptor activity 3/1050 18/18639 0.166666666666667 2.95857142857143 0.077342221914237 0.389845863868789 GO:0070064 proline-rich region binding 3/1050 18/18639 0.166666666666667 2.95857142857143 0.077342221914237 0.389845863868789 GO:1990381 ubiquitin-specific protease binding 3/1050 18/18639 0.166666666666667 2.95857142857143 0.077342221914237 0.389845863868789 GO:0003785 actin monomer binding 4/1050 29/18639 0.137931034482759 2.44847290640394 0.077669002714956 0.389845863868789 GO:0042169 SH2 domain binding 5/1050 41/18639 0.121951219512195 2.16480836236934 0.0788413852478579 0.393827881117906 GO:0035173 histone kinase activity 27/1050 360/18639 0.075 1.33135714285714 0.0797316422091017 0.396369264379219 GO:0015485 cholesterol binding 6/1050 54/18639 0.111111111111111 1.97238095238095 0.0819945451813607 0.403755130063667 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 6/1050 54/18639 0.111111111111111 1.97238095238095 0.0819945451813607 0.403755130063667 GO:0097001 ceramide binding 3/1050 19/18639 0.157894736842105 2.80285714285714 0.0881532793711075 0.432034232389532 GO:0004712 protein serine/threonine/tyrosine kinase activity 5/1050 43/18639 0.116279069767442 2.0641196013289 0.0925622195978297 0.449935370259669 GO:0070325 lipoprotein particle receptor binding 4/1050 31/18639 0.129032258064516 2.2905069124424 0.0943497099544607 0.449935370259669 GO:0008135 translation factor activity, RNA binding 8/1050 83/18639 0.0963855421686747 1.71098106712565 0.0951650706981345 0.449935370259669 GO:0061135 endopeptidase regulator activity 15/1050 184/18639 0.0815217391304348 1.44712732919255 0.0965109892910359 0.449935370259669 GO:0046982 protein heterodimerization activity 27/1050 369/18639 0.0731707317073171 1.2988850174216 0.0994944318732259 0.449935370259669 GO:0001614 purinergic nucleotide receptor activity 3/1050 20/18639 0.15 2.66271428571429 0.0995568035421512 0.449935370259669 GO:0016004 phospholipase activator activity 3/1050 20/18639 0.15 2.66271428571429 0.0995568035421512 0.449935370259669 GO:0016502 nucleotide receptor activity 3/1050 20/18639 0.15 2.66271428571429 0.0995568035421512 0.449935370259669 GO:0030742 GTP-dependent protein binding 3/1050 20/18639 0.15 2.66271428571429 0.0995568035421512 0.449935370259669 GO:0043024 ribosomal small subunit binding 3/1050 20/18639 0.15 2.66271428571429 0.0995568035421512 0.449935370259669 GO:0004527 exonuclease activity 8/1050 84/18639 0.0952380952380952 1.69061224489796 0.100292008509864 0.449935370259669 GO:0004860 protein kinase inhibitor activity 8/1050 84/18639 0.0952380952380952 1.69061224489796 0.100292008509864 0.449935370259669 GO:0051117 ATPase binding 8/1050 84/18639 0.0952380952380952 1.69061224489796 0.100292008509864 0.449935370259669 GO:0180051 translation factor activity 8/1050 84/18639 0.0952380952380952 1.69061224489796 0.100292008509864 0.449935370259669 GO:0004601 peroxidase activity 6/1050 57/18639 0.105263157894737 1.86857142857143 0.100336095020041 0.449935370259669 GO:0004674 protein serine/threonine kinase activity 31/1050 433/18639 0.0715935334872979 1.27088749587595 0.101707671651085 0.449935370259669 GO:0022884 macromolecule transmembrane transporter activity 4/1050 32/18639 0.125 2.21892857142857 0.103271591602297 0.449935370259669 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/1050 32/18639 0.125 2.21892857142857 0.103271591602297 0.449935370259669 GO:0043425 bHLH transcription factor binding 4/1050 32/18639 0.125 2.21892857142857 0.103271591602297 0.449935370259669 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/1050 10/18639 0.2 3.55028571428571 0.105663359329508 0.449935370259669 GO:0004935 adrenergic receptor activity 2/1050 10/18639 0.2 3.55028571428571 0.105663359329508 0.449935370259669 GO:0005381 iron ion transmembrane transporter activity 2/1050 10/18639 0.2 3.55028571428571 0.105663359329508 0.449935370259669 GO:0008140 cAMP response element binding protein binding 2/1050 10/18639 0.2 3.55028571428571 0.105663359329508 0.449935370259669 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/1050 10/18639 0.2 3.55028571428571 0.105663359329508 0.449935370259669 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/1050 10/18639 0.2 3.55028571428571 0.105663359329508 0.449935370259669 GO:0043208 glycosphingolipid binding 2/1050 10/18639 0.2 3.55028571428571 0.105663359329508 0.449935370259669 GO:0043422 protein kinase B binding 2/1050 10/18639 0.2 3.55028571428571 0.105663359329508 0.449935370259669 GO:0047429 nucleoside triphosphate diphosphatase activity 2/1050 10/18639 0.2 3.55028571428571 0.105663359329508 0.449935370259669 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/1050 10/18639 0.2 3.55028571428571 0.105663359329508 0.449935370259669 GO:0051880 G-quadruplex DNA binding 2/1050 10/18639 0.2 3.55028571428571 0.105663359329508 0.449935370259669 GO:0070097 delta-catenin binding 2/1050 10/18639 0.2 3.55028571428571 0.105663359329508 0.449935370259669 GO:1990757 ubiquitin ligase activator activity 2/1050 10/18639 0.2 3.55028571428571 0.105663359329508 0.449935370259669 GO:0016209 antioxidant activity 8/1050 86/18639 0.0930232558139535 1.65129568106312 0.11100055314617 0.470732958036206 GO:0061891 calcium ion sensor activity 3/1050 21/18639 0.142857142857143 2.53591836734694 0.111514882609148 0.470991719637826 GO:0001786 phosphatidylserine binding 6/1050 59/18639 0.101694915254237 1.80523002421308 0.113663681325849 0.476195826199827 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 6/1050 59/18639 0.101694915254237 1.80523002421308 0.113663681325849 0.476195826199827 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6/1050 60/18639 0.1 1.77514285714286 0.12064644007905 0.49370190770481 GO:0098531 ligand-modulated transcription factor activity 6/1050 60/18639 0.1 1.77514285714286 0.12064644007905 0.49370190770481 GO:0031683 G-protein beta/gamma-subunit complex binding 3/1050 22/18639 0.136363636363636 2.42064935064935 0.123988446825471 0.49370190770481 GO:0033691 sialic acid binding 3/1050 22/18639 0.136363636363636 2.42064935064935 0.123988446825471 0.49370190770481 GO:0140784 metal ion sensor activity 3/1050 22/18639 0.136363636363636 2.42064935064935 0.123988446825471 0.49370190770481 GO:0008432 JUN kinase binding 2/1050 11/18639 0.181818181818182 3.22753246753247 0.124494610027584 0.49370190770481 GO:0019107 myristoyltransferase activity 2/1050 11/18639 0.181818181818182 3.22753246753247 0.124494610027584 0.49370190770481 GO:0019215 intermediate filament binding 2/1050 11/18639 0.181818181818182 3.22753246753247 0.124494610027584 0.49370190770481 GO:0032050 clathrin heavy chain binding 2/1050 11/18639 0.181818181818182 3.22753246753247 0.124494610027584 0.49370190770481 GO:0032794 GTPase activating protein binding 2/1050 11/18639 0.181818181818182 3.22753246753247 0.124494610027584 0.49370190770481 GO:0034713 type I transforming growth factor beta receptor binding 2/1050 11/18639 0.181818181818182 3.22753246753247 0.124494610027584 0.49370190770481 GO:0048185 activin binding 2/1050 11/18639 0.181818181818182 3.22753246753247 0.124494610027584 0.49370190770481 GO:0050998 nitric-oxide synthase binding 2/1050 11/18639 0.181818181818182 3.22753246753247 0.124494610027584 0.49370190770481 GO:0140537 transcription regulator activator activity 2/1050 11/18639 0.181818181818182 3.22753246753247 0.124494610027584 0.49370190770481 GO:0004722 protein serine/threonine phosphatase activity 9/1050 103/18639 0.087378640776699 1.55109570041609 0.126249270220716 0.498756622659027 GO:0015026 coreceptor activity 6/1050 61/18639 0.0983606557377049 1.74604215456674 0.127835945810587 0.503111923095455 GO:0016229 steroid dehydrogenase activity 4/1050 35/18639 0.114285714285714 2.02873469387755 0.132193605875072 0.516350212421803 GO:0043015 gamma-tubulin binding 4/1050 35/18639 0.114285714285714 2.02873469387755 0.132193605875072 0.516350212421803 GO:0019210 kinase inhibitor activity 8/1050 90/18639 0.0888888888888889 1.57790476190476 0.134191805190099 0.517847398091588 GO:0005212 structural constituent of eye lens 3/1050 23/18639 0.130434782608696 2.31540372670807 0.136937717685914 0.517847398091588 GO:0017134 fibroblast growth factor binding 3/1050 23/18639 0.130434782608696 2.31540372670807 0.136937717685914 0.517847398091588 GO:0031681 G-protein beta-subunit binding 3/1050 23/18639 0.130434782608696 2.31540372670807 0.136937717685914 0.517847398091588 GO:0043274 phospholipase binding 3/1050 23/18639 0.130434782608696 2.31540372670807 0.136937717685914 0.517847398091588 GO:0016853 isomerase activity 14/1050 180/18639 0.0777777777777778 1.38066666666667 0.138537811812838 0.517847398091588 GO:0005484 SNAP receptor activity 4/1050 36/18639 0.111111111111111 1.97238095238095 0.142500305308429 0.517847398091588 GO:0005507 copper ion binding 6/1050 63/18639 0.0952380952380952 1.69061224489796 0.142815159360612 0.517847398091588 GO:0015399 primary active transmembrane transporter activity 13/1050 166/18639 0.0783132530120482 1.39017211703959 0.144002643109478 0.517847398091588 GO:0004300 enoyl-CoA hydratase activity 2/1050 12/18639 0.166666666666667 2.95857142857143 0.144043607558151 0.517847398091588 GO:0005025 transforming growth factor beta receptor activity, type I 2/1050 12/18639 0.166666666666667 2.95857142857143 0.144043607558151 0.517847398091588 GO:0005026 transforming growth factor beta receptor activity, type II 2/1050 12/18639 0.166666666666667 2.95857142857143 0.144043607558151 0.517847398091588 GO:0005095 GTPase inhibitor activity 2/1050 12/18639 0.166666666666667 2.95857142857143 0.144043607558151 0.517847398091588 GO:0008179 adenylate cyclase binding 2/1050 12/18639 0.166666666666667 2.95857142857143 0.144043607558151 0.517847398091588 GO:0015132 prostaglandin transmembrane transporter activity 2/1050 12/18639 0.166666666666667 2.95857142857143 0.144043607558151 0.517847398091588 GO:0015269 calcium-activated potassium channel activity 2/1050 12/18639 0.166666666666667 2.95857142857143 0.144043607558151 0.517847398091588 GO:0016361 activin receptor activity, type I 2/1050 12/18639 0.166666666666667 2.95857142857143 0.144043607558151 0.517847398091588 GO:0016362 activin receptor activity, type II 2/1050 12/18639 0.166666666666667 2.95857142857143 0.144043607558151 0.517847398091588 GO:0017002 activin receptor activity 2/1050 12/18639 0.166666666666667 2.95857142857143 0.144043607558151 0.517847398091588 GO:0034452 dynactin binding 2/1050 12/18639 0.166666666666667 2.95857142857143 0.144043607558151 0.517847398091588 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/1050 12/18639 0.166666666666667 2.95857142857143 0.144043607558151 0.517847398091588 GO:0035497 cAMP response element binding 2/1050 12/18639 0.166666666666667 2.95857142857143 0.144043607558151 0.517847398091588 GO:0097371 MDM2/MDM4 family protein binding 2/1050 12/18639 0.166666666666667 2.95857142857143 0.144043607558151 0.517847398091588 GO:0003697 single-stranded DNA binding 10/1050 121/18639 0.0826446280991736 1.46706021251476 0.14453873478976 0.517847398091588 GO:0043178 alcohol binding 8/1050 92/18639 0.0869565217391304 1.54360248447205 0.14664154958389 0.523575841985093 GO:0016922 nuclear receptor binding 11/1050 137/18639 0.0802919708029197 1.42529718456726 0.150169148654713 0.529441289834831 GO:0019957 C-C chemokine binding 3/1050 24/18639 0.125 2.21892857142857 0.15032259913501 0.529441289834831 GO:0050699 WW domain binding 3/1050 24/18639 0.125 2.21892857142857 0.15032259913501 0.529441289834831 GO:0060229 lipase activator activity 3/1050 24/18639 0.125 2.21892857142857 0.15032259913501 0.529441289834831 GO:0046332 SMAD binding 7/1050 79/18639 0.0886075949367089 1.57291139240506 0.156456197605119 0.548392869587934 GO:0001217 DNA-binding transcription repressor activity 20/1050 278/18639 0.0719424460431655 1.27708119218911 0.156759078217148 0.548392869587934 GO:0003743 translation initiation factor activity 5/1050 51/18639 0.0980392156862745 1.74033613445378 0.158249350668053 0.551748574980226 GO:0015078 proton transmembrane transporter activity 14/1050 185/18639 0.0756756756756757 1.34335135135135 0.160921098329354 0.557426638550647 GO:0042162 telomeric DNA binding 4/1050 38/18639 0.105263157894737 1.86857142857143 0.164010211363431 0.557426638550647 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 3/1050 25/18639 0.12 2.13017142857143 0.164103016528474 0.557426638550647 GO:0004535 poly(A)-specific ribonuclease activity 2/1050 13/18639 0.153846153846154 2.73098901098901 0.164169924346966 0.557426638550647 GO:0015651 quaternary ammonium group transmembrane transporter activity 2/1050 13/18639 0.153846153846154 2.73098901098901 0.164169924346966 0.557426638550647 GO:0046974 histone H3K9 methyltransferase activity 2/1050 13/18639 0.153846153846154 2.73098901098901 0.164169924346966 0.557426638550647 GO:0070123 transforming growth factor beta receptor activity, type III 2/1050 13/18639 0.153846153846154 2.73098901098901 0.164169924346966 0.557426638550647 GO:0071714 icosanoid transmembrane transporter activity 2/1050 13/18639 0.153846153846154 2.73098901098901 0.164169924346966 0.557426638550647 GO:0005080 protein kinase C binding 5/1050 52/18639 0.0961538461538462 1.70686813186813 0.167541987505645 0.565390645159362 GO:0106310 protein serine kinase activity 25/1050 361/18639 0.0692520775623269 1.22932330827068 0.167603771616057 0.565390645159362 GO:0030971 receptor tyrosine kinase binding 7/1050 81/18639 0.0864197530864197 1.53407407407407 0.171131266429158 0.575421960582186 GO:0016860 intramolecular oxidoreductase activity 5/1050 53/18639 0.0943396226415094 1.67466307277628 0.177043021652565 0.591663059754607 GO:0004529 DNA exonuclease activity 3/1050 26/18639 0.115384615384615 2.04824175824176 0.178239208569001 0.591663059754607 GO:0005160 transforming growth factor beta receptor binding 3/1050 26/18639 0.115384615384615 2.04824175824176 0.178239208569001 0.591663059754607 GO:0050750 low-density lipoprotein particle receptor binding 3/1050 26/18639 0.115384615384615 2.04824175824176 0.178239208569001 0.591663059754607 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 19/1050 268/18639 0.0708955223880597 1.25849680170576 0.179790549845954 0.593863860601494 GO:0005200 structural constituent of cytoskeleton 9/1050 112/18639 0.0803571428571429 1.42645408163265 0.180045347535583 0.593863860601494 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 2/1050 14/18639 0.142857142857143 2.53591836734694 0.184746650226022 0.596123508027442 GO:0032036 myosin heavy chain binding 2/1050 14/18639 0.142857142857143 2.53591836734694 0.184746650226022 0.596123508027442 GO:0042813 Wnt receptor activity 2/1050 14/18639 0.142857142857143 2.53591836734694 0.184746650226022 0.596123508027442 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 2/1050 14/18639 0.142857142857143 2.53591836734694 0.184746650226022 0.596123508027442 GO:0071933 Arp2/3 complex binding 2/1050 14/18639 0.142857142857143 2.53591836734694 0.184746650226022 0.596123508027442 GO:0098821 BMP receptor activity 2/1050 14/18639 0.142857142857143 2.53591836734694 0.184746650226022 0.596123508027442 GO:0098847 sequence-specific single stranded DNA binding 2/1050 14/18639 0.142857142857143 2.53591836734694 0.184746650226022 0.596123508027442 GO:0061791 GTPase motor activity 4/1050 40/18639 0.1 1.77514285714286 0.186594874455509 0.598370600491585 GO:1990606 membrane scission GTPase motor activity 4/1050 40/18639 0.1 1.77514285714286 0.186594874455509 0.598370600491585 GO:0004721 phosphoprotein phosphatase activity 13/1050 175/18639 0.0742857142857143 1.31867755102041 0.188453961205099 0.602472817514146 GO:0019887 protein kinase regulator activity 18/1050 255/18639 0.0705882352941176 1.25304201680672 0.192446672383156 0.61225371280081 GO:0015252 proton channel activity 3/1050 27/18639 0.111111111111111 1.97238095238095 0.192691976983508 0.61225371280081 GO:0001530 lipopolysaccharide binding 4/1050 41/18639 0.0975609756097561 1.73184668989547 0.198243900315795 0.626065083368119 GO:0140318 protein transporter activity 4/1050 41/18639 0.0975609756097561 1.73184668989547 0.198243900315795 0.626065083368119 GO:0004953 icosanoid receptor activity 2/1050 15/18639 0.133333333333333 2.36685714285714 0.205659317446945 0.634065373375003 GO:0031386 protein tag activity 2/1050 15/18639 0.133333333333333 2.36685714285714 0.205659317446945 0.634065373375003 GO:0034483 heparan sulfate sulfotransferase activity 2/1050 15/18639 0.133333333333333 2.36685714285714 0.205659317446945 0.634065373375003 GO:0050700 CARD domain binding 2/1050 15/18639 0.133333333333333 2.36685714285714 0.205659317446945 0.634065373375003 GO:0050780 dopamine receptor binding 2/1050 15/18639 0.133333333333333 2.36685714285714 0.205659317446945 0.634065373375003 GO:0061578 K63-linked deubiquitinase activity 2/1050 15/18639 0.133333333333333 2.36685714285714 0.205659317446945 0.634065373375003 GO:0120283 protein serine/threonine kinase binding 2/1050 15/18639 0.133333333333333 2.36685714285714 0.205659317446945 0.634065373375003 GO:0141047 molecular tag activity 2/1050 15/18639 0.133333333333333 2.36685714285714 0.205659317446945 0.634065373375003 GO:0046875 ephrin receptor binding 3/1050 28/18639 0.107142857142857 1.9019387755102 0.207422898291099 0.635729767918736 GO:0050698 proteoglycan sulfotransferase activity 3/1050 28/18639 0.107142857142857 1.9019387755102 0.207422898291099 0.635729767918736 GO:0140299 molecular sensor activity 6/1050 71/18639 0.0845070422535211 1.50012072434608 0.209857312633932 0.640175402897257 GO:0019894 kinesin binding 4/1050 42/18639 0.0952380952380952 1.69061224489796 0.210105690460024 0.640175402897257 GO:0019208 phosphatase regulator activity 9/1050 117/18639 0.0769230769230769 1.36549450549451 0.213735786703529 0.649331819839084 GO:0008200 ion channel inhibitor activity 4/1050 43/18639 0.0930232558139535 1.65129568106312 0.222161431061275 0.671005019978675 GO:0008375 acetylglucosaminyltransferase activity 4/1050 43/18639 0.0930232558139535 1.65129568106312 0.222161431061275 0.671005019978675 GO:0000062 fatty-acyl-CoA binding 2/1050 16/18639 0.125 2.21892857142857 0.226804903733934 0.67328655708445 GO:0004708 MAP kinase kinase activity 2/1050 16/18639 0.125 2.21892857142857 0.226804903733934 0.67328655708445 GO:0005024 transforming growth factor beta receptor activity 2/1050 16/18639 0.125 2.21892857142857 0.226804903733934 0.67328655708445 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/1050 16/18639 0.125 2.21892857142857 0.226804903733934 0.67328655708445 GO:0019841 retinol binding 2/1050 16/18639 0.125 2.21892857142857 0.226804903733934 0.67328655708445 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/1050 16/18639 0.125 2.21892857142857 0.226804903733934 0.67328655708445 GO:0004521 RNA endonuclease activity 6/1050 73/18639 0.0821917808219178 1.45902152641879 0.228126658077865 0.673362493587788 GO:0043539 protein serine/threonine kinase activator activity 6/1050 73/18639 0.0821917808219178 1.45902152641879 0.228126658077865 0.673362493587788 GO:0001223 transcription coactivator binding 4/1050 44/18639 0.0909090909090909 1.61376623376623 0.234392374066133 0.687948239137605 GO:0016248 channel inhibitor activity 4/1050 44/18639 0.0909090909090909 1.61376623376623 0.234392374066133 0.687948239137605 GO:0001965 G-protein alpha-subunit binding 3/1050 30/18639 0.1 1.77514285714286 0.237570416232986 0.692132509348681 GO:0004879 nuclear receptor activity 5/1050 59/18639 0.0847457627118644 1.5043583535109 0.237816463751183 0.692132509348681 GO:0015459 potassium channel regulator activity 5/1050 59/18639 0.0847457627118644 1.5043583535109 0.237816463751183 0.692132509348681 GO:0140303 intramembrane lipid transporter activity 4/1050 45/18639 0.0888888888888889 1.57790476190476 0.246779910745754 0.704279927377519 GO:0141110 transporter inhibitor activity 4/1050 45/18639 0.0888888888888889 1.57790476190476 0.246779910745754 0.704279927377519 GO:0004550 nucleoside diphosphate kinase activity 2/1050 17/18639 0.117647058823529 2.08840336134454 0.248090908007865 0.704279927377519 GO:0005092 GDP-dissociation inhibitor activity 2/1050 17/18639 0.117647058823529 2.08840336134454 0.248090908007865 0.704279927377519 GO:0008429 phosphatidylethanolamine binding 2/1050 17/18639 0.117647058823529 2.08840336134454 0.248090908007865 0.704279927377519 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/1050 17/18639 0.117647058823529 2.08840336134454 0.248090908007865 0.704279927377519 GO:0032977 membrane insertase activity 2/1050 17/18639 0.117647058823529 2.08840336134454 0.248090908007865 0.704279927377519 GO:0046965 nuclear retinoid X receptor binding 2/1050 17/18639 0.117647058823529 2.08840336134454 0.248090908007865 0.704279927377519 GO:1901567 fatty acid derivative binding 2/1050 17/18639 0.117647058823529 2.08840336134454 0.248090908007865 0.704279927377519 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 9/1050 122/18639 0.0737704918032787 1.30953161592506 0.249686548311218 0.706878266199878 GO:0072341 modified amino acid binding 7/1050 91/18639 0.0769230769230769 1.36549450549451 0.252276444482026 0.712269635371807 GO:0098631 cell adhesion mediator activity 6/1050 76/18639 0.0789473684210526 1.40142857142857 0.256419118056843 0.722003966561137 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 5/1050 61/18639 0.0819672131147541 1.45503512880562 0.259239028573801 0.72424343719336 GO:0030276 clathrin binding 4/1050 46/18639 0.0869565217391304 1.54360248447205 0.259305638725631 0.72424343719336 GO:0030291 protein serine/threonine kinase inhibitor activity 4/1050 46/18639 0.0869565217391304 1.54360248447205 0.259305638725631 0.72424343719336 GO:0003714 transcription corepressor activity 14/1050 204/18639 0.0686274509803922 1.21823529411765 0.260825504006699 0.72653538515539 GO:0042910 xenobiotic transmembrane transporter activity 3/1050 32/18639 0.09375 1.66419642857143 0.268395895385346 0.733715473903535 GO:0051059 NF-kappaB binding 3/1050 32/18639 0.09375 1.66419642857143 0.268395895385346 0.733715473903535 GO:0070717 poly-purine tract binding 3/1050 32/18639 0.09375 1.66419642857143 0.268395895385346 0.733715473903535 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/1050 18/18639 0.111111111111111 1.97238095238095 0.269434493769568 0.733715473903535 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/1050 18/18639 0.111111111111111 1.97238095238095 0.269434493769568 0.733715473903535 GO:0031690 adrenergic receptor binding 2/1050 18/18639 0.111111111111111 1.97238095238095 0.269434493769568 0.733715473903535 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/1050 18/18639 0.111111111111111 1.97238095238095 0.269434493769568 0.733715473903535 GO:0050811 GABA receptor binding 2/1050 18/18639 0.111111111111111 1.97238095238095 0.269434493769568 0.733715473903535 GO:0051219 phosphoprotein binding 7/1050 93/18639 0.0752688172043011 1.33612903225806 0.269758720915448 0.733715473903535 GO:0001784 phosphotyrosine residue binding 4/1050 47/18639 0.0851063829787234 1.51075987841945 0.271951422707466 0.733915657644305 GO:0005504 fatty acid binding 4/1050 47/18639 0.0851063829787234 1.51075987841945 0.271951422707466 0.733915657644305 GO:0043495 protein-membrane adaptor activity 4/1050 47/18639 0.0851063829787234 1.51075987841945 0.271951422707466 0.733915657644305 GO:0019199 transmembrane receptor protein kinase activity 6/1050 78/18639 0.0769230769230769 1.36549450549451 0.275781377618757 0.739741311112517 GO:0042562 hormone binding 7/1050 94/18639 0.074468085106383 1.32191489361702 0.278619368443892 0.739741311112517 GO:0140311 protein sequestering activity 3/1050 33/18639 0.0909090909090909 1.61376623376623 0.283979185407544 0.739741311112517 GO:0140416 transcription regulator inhibitor activity 3/1050 33/18639 0.0909090909090909 1.61376623376623 0.283979185407544 0.739741311112517 GO:0004519 endonuclease activity 9/1050 127/18639 0.0708661417322835 1.25797525309336 0.287474846055245 0.739741311112517 GO:0005229 intracellularly calcium-gated chloride channel activity 2/1050 19/18639 0.105263157894737 1.86857142857143 0.290761695463505 0.739741311112517 GO:0008301 DNA binding, bending 2/1050 19/18639 0.105263157894737 1.86857142857143 0.290761695463505 0.739741311112517 GO:0016918 retinal binding 2/1050 19/18639 0.105263157894737 1.86857142857143 0.290761695463505 0.739741311112517 GO:0030506 ankyrin binding 2/1050 19/18639 0.105263157894737 1.86857142857143 0.290761695463505 0.739741311112517 GO:0034987 immunoglobulin receptor binding 2/1050 19/18639 0.105263157894737 1.86857142857143 0.290761695463505 0.739741311112517 GO:0042834 peptidoglycan binding 2/1050 19/18639 0.105263157894737 1.86857142857143 0.290761695463505 0.739741311112517 GO:0043395 heparan sulfate proteoglycan binding 2/1050 19/18639 0.105263157894737 1.86857142857143 0.290761695463505 0.739741311112517 GO:0120227 acyl-CoA binding 2/1050 19/18639 0.105263157894737 1.86857142857143 0.290761695463505 0.739741311112517 GO:0141147 intracellularly calcium-gated channel activity 2/1050 19/18639 0.105263157894737 1.86857142857143 0.290761695463505 0.739741311112517 GO:0048306 calcium-dependent protein binding 6/1050 80/18639 0.075 1.33135714285714 0.295470197989065 0.739741311112517 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 16/1050 243/18639 0.065843621399177 1.16881834215168 0.295626039375923 0.739741311112517 GO:0005004 GPI-linked ephrin receptor activity 4/1050 49/18639 0.0816326530612245 1.44909620991254 0.297532274946308 0.739741311112517 GO:0005008 hepatocyte growth factor receptor activity 4/1050 49/18639 0.0816326530612245 1.44909620991254 0.297532274946308 0.739741311112517 GO:0005009 insulin receptor activity 4/1050 49/18639 0.0816326530612245 1.44909620991254 0.297532274946308 0.739741311112517 GO:0005011 macrophage colony-stimulating factor receptor activity 4/1050 49/18639 0.0816326530612245 1.44909620991254 0.297532274946308 0.739741311112517 GO:0005018 platelet-derived growth factor alpha-receptor activity 4/1050 49/18639 0.0816326530612245 1.44909620991254 0.297532274946308 0.739741311112517 GO:0005020 stem cell factor receptor activity 4/1050 49/18639 0.0816326530612245 1.44909620991254 0.297532274946308 0.739741311112517 GO:0008288 boss receptor activity 4/1050 49/18639 0.0816326530612245 1.44909620991254 0.297532274946308 0.739741311112517 GO:0036332 placental growth factor receptor activity 4/1050 49/18639 0.0816326530612245 1.44909620991254 0.297532274946308 0.739741311112517 GO:0038062 protein tyrosine kinase collagen receptor activity 4/1050 49/18639 0.0816326530612245 1.44909620991254 0.297532274946308 0.739741311112517 GO:0060175 brain-derived neurotrophic factor receptor activity 4/1050 49/18639 0.0816326530612245 1.44909620991254 0.297532274946308 0.739741311112517 GO:0008236 serine-type peptidase activity 13/1050 194/18639 0.0670103092783505 1.18952871870398 0.29941297060124 0.739741311112517 GO:0005543 phospholipid binding 31/1050 497/18639 0.062374245472837 1.10723196320782 0.303554104977639 0.739741311112517 GO:0004676 3-phosphoinositide-dependent protein kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0004711 ribosomal protein S6 kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0035175 histone H3S10 kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0035979 histone H2AXS139 kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0044022 histone H3S28 kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0044023 histone H4S1 kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0044024 histone H2AS1 kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0044025 histone H2BS14 kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0072354 histone H3T3 kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0072371 histone H2AS121 kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0072518 Rho-dependent protein serine/threonine kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0140823 histone H2BS36 kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0140855 histone H3S57 kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0140995 histone H2A kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0140997 histone H4 kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0140998 histone H2B kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:1990244 histone H2AT120 kinase activity 16/1050 245/18639 0.0653061224489796 1.15927696793003 0.306882585424845 0.739741311112517 GO:0005006 epidermal growth factor receptor activity 4/1050 50/18639 0.08 1.42011428571429 0.310432871011593 0.739741311112517 GO:0005007 fibroblast growth factor receptor activity 4/1050 50/18639 0.08 1.42011428571429 0.310432871011593 0.739741311112517 GO:0005017 platelet-derived growth factor receptor activity 4/1050 50/18639 0.08 1.42011428571429 0.310432871011593 0.739741311112517 GO:0005019 platelet-derived growth factor beta-receptor activity 4/1050 50/18639 0.08 1.42011428571429 0.310432871011593 0.739741311112517 GO:0048020 CCR chemokine receptor binding 4/1050 50/18639 0.08 1.42011428571429 0.310432871011593 0.739741311112517 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 2/1050 20/18639 0.1 1.77514285714286 0.312006683454766 0.739741311112517 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/1050 20/18639 0.1 1.77514285714286 0.312006683454766 0.739741311112517 GO:0004677 DNA-dependent protein kinase activity 16/1050 246/18639 0.0650406504065041 1.15456445993031 0.312556723367079 0.739741311112517 GO:0140857 histone H3T45 kinase activity 16/1050 246/18639 0.0650406504065041 1.15456445993031 0.312556723367079 0.739741311112517 GO:0008235 metalloexopeptidase activity 5/1050 66/18639 0.0757575757575758 1.34480519480519 0.314478787577221 0.742598773392575 GO:0035402 histone H3T11 kinase activity 16/1050 247/18639 0.0647773279352227 1.14989010989011 0.31825961539349 0.748126109488317 GO:0035403 histone H3T6 kinase activity 16/1050 247/18639 0.0647773279352227 1.14989010989011 0.31825961539349 0.748126109488317 GO:0019209 kinase activator activity 10/1050 148/18639 0.0675675675675676 1.19942084942085 0.323096722528222 0.753077153470073 GO:0005010 insulin-like growth factor receptor activity 4/1050 51/18639 0.0784313725490196 1.39226890756303 0.323384659977 0.753077153470073 GO:0005021 vascular endothelial growth factor receptor activity 4/1050 51/18639 0.0784313725490196 1.39226890756303 0.323384659977 0.753077153470073 GO:0005030 neurotrophin receptor activity 4/1050 51/18639 0.0784313725490196 1.39226890756303 0.323384659977 0.753077153470073 GO:0004679 AMP-activated protein kinase activity 16/1050 248/18639 0.0645161290322581 1.1452534562212 0.323989882195498 0.753077153470073 GO:0017171 serine hydrolase activity 13/1050 198/18639 0.0656565656565657 1.16549783549784 0.324930951422408 0.753165836428179 GO:0030165 PDZ domain binding 6/1050 83/18639 0.072289156626506 1.28323580034423 0.325477825366942 0.753165836428179 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 9/1050 132/18639 0.0681818181818182 1.21032467532468 0.326647588220357 0.754192987024336 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/1050 21/18639 0.0952380952380952 1.69061224489796 0.333111083543779 0.760664650114257 GO:0008373 sialyltransferase activity 2/1050 21/18639 0.0952380952380952 1.69061224489796 0.333111083543779 0.760664650114257 GO:0035613 RNA stem-loop binding 2/1050 21/18639 0.0952380952380952 1.69061224489796 0.333111083543779 0.760664650114257 GO:0070182 DNA polymerase binding 2/1050 21/18639 0.0952380952380952 1.69061224489796 0.333111083543779 0.760664650114257 GO:0072542 protein phosphatase activator activity 2/1050 21/18639 0.0952380952380952 1.69061224489796 0.333111083543779 0.760664650114257 GO:0030159 signaling receptor complex adaptor activity 4/1050 52/18639 0.0769230769230769 1.36549450549451 0.336371549349613 0.764536222321912 GO:0005548 phospholipid transporter activity 5/1050 68/18639 0.0735294117647059 1.30525210084034 0.337014042178475 0.764536222321912 GO:0030145 manganese ion binding 5/1050 68/18639 0.0735294117647059 1.30525210084034 0.337014042178475 0.764536222321912 GO:0005003 ephrin receptor activity 4/1050 53/18639 0.0754716981132075 1.33973045822102 0.349377959773862 0.782915553382701 GO:0005005 transmembrane-ephrin receptor activity 4/1050 53/18639 0.0754716981132075 1.33973045822102 0.349377959773862 0.782915553382701 GO:0005246 calcium channel regulator activity 4/1050 53/18639 0.0754716981132075 1.33973045822102 0.349377959773862 0.782915553382701 GO:0038064 collagen receptor activity 4/1050 53/18639 0.0754716981132075 1.33973045822102 0.349377959773862 0.782915553382701 GO:0051018 protein kinase A binding 4/1050 53/18639 0.0754716981132075 1.33973045822102 0.349377959773862 0.782915553382701 GO:1901981 phosphatidylinositol phosphate binding 12/1050 185/18639 0.0648648648648649 1.15144401544402 0.349636974754161 0.782915553382701 GO:0030414 peptidase inhibitor activity 11/1050 169/18639 0.0650887573964497 1.15541842772612 0.355095471266926 0.793428375583519 GO:0044325 transmembrane transporter binding 9/1050 136/18639 0.0661764705882353 1.1747268907563 0.358669828494625 0.799695175549175 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 3/1050 38/18639 0.0789473684210526 1.40142857142857 0.362406680492514 0.804573805623338 GO:0042887 amide transmembrane transporter activity 3/1050 38/18639 0.0789473684210526 1.40142857142857 0.362406680492514 0.804573805623338 GO:0008234 cysteine-type peptidase activity 12/1050 187/18639 0.0641711229946524 1.13912910618793 0.363358126175653 0.804966083361416 GO:0008081 phosphoric diester hydrolase activity 6/1050 87/18639 0.0689655172413793 1.22423645320197 0.366049794551862 0.809203694764648 GO:0004022 alcohol dehydrogenase (NAD+) activity 2/1050 23/18639 0.0869565217391304 1.54360248447205 0.374698169075581 0.819602942462166 GO:0005158 insulin receptor binding 2/1050 23/18639 0.0869565217391304 1.54360248447205 0.374698169075581 0.819602942462166 GO:0016493 C-C chemokine receptor activity 2/1050 23/18639 0.0869565217391304 1.54360248447205 0.374698169075581 0.819602942462166 GO:0042171 lysophosphatidic acid acyltransferase activity 2/1050 23/18639 0.0869565217391304 1.54360248447205 0.374698169075581 0.819602942462166 GO:0071617 lysophospholipid acyltransferase activity 2/1050 23/18639 0.0869565217391304 1.54360248447205 0.374698169075581 0.819602942462166 GO:0000217 DNA secondary structure binding 3/1050 39/18639 0.0769230769230769 1.36549450549451 0.378009119515021 0.825108141126275 GO:0170055 lipid transmembrane transporter activity 4/1050 56/18639 0.0714285714285714 1.26795918367347 0.388366693182799 0.825356303382564 GO:0005539 glycosaminoglycan binding 15/1050 242/18639 0.0619834710743802 1.10029515938607 0.389224873281816 0.825356303382564 GO:0042578 phosphoric ester hydrolase activity 22/1050 363/18639 0.0606060606060606 1.07584415584416 0.392704109586643 0.825356303382564 GO:0004532 RNA exonuclease activity 3/1050 40/18639 0.075 1.33135714285714 0.393529193438765 0.825356303382564 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/1050 40/18639 0.075 1.33135714285714 0.393529193438765 0.825356303382564 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/1050 24/18639 0.0833333333333333 1.47928571428571 0.395095948161087 0.825356303382564 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/1050 24/18639 0.0833333333333333 1.47928571428571 0.395095948161087 0.825356303382564 GO:0005540 hyaluronic acid binding 2/1050 24/18639 0.0833333333333333 1.47928571428571 0.395095948161087 0.825356303382564 GO:0015295 solute:proton symporter activity 2/1050 24/18639 0.0833333333333333 1.47928571428571 0.395095948161087 0.825356303382564 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/1050 24/18639 0.0833333333333333 1.47928571428571 0.395095948161087 0.825356303382564 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/1050 24/18639 0.0833333333333333 1.47928571428571 0.395095948161087 0.825356303382564 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/1050 24/18639 0.0833333333333333 1.47928571428571 0.395095948161087 0.825356303382564 GO:0070840 dynein complex binding 2/1050 24/18639 0.0833333333333333 1.47928571428571 0.395095948161087 0.825356303382564 GO:0019888 protein phosphatase regulator activity 7/1050 107/18639 0.0654205607476635 1.16130841121495 0.398215738740338 0.825356303382564 GO:0048029 monosaccharide binding 5/1050 74/18639 0.0675675675675676 1.19942084942085 0.405037137175926 0.825356303382564 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/1050 41/18639 0.0731707317073171 1.2988850174216 0.408946453422158 0.825356303382564 GO:0017080 sodium channel regulator activity 3/1050 41/18639 0.0731707317073171 1.2988850174216 0.408946453422158 0.825356303382564 GO:0008408 3'-5' exonuclease activity 4/1050 58/18639 0.0689655172413793 1.22423645320197 0.414196137717238 0.825356303382564 GO:0030695 GTPase regulator activity 29/1050 489/18639 0.0593047034764826 1.05274320771253 0.414414736383063 0.825356303382564 GO:0003707 nuclear steroid receptor activity 2/1050 25/18639 0.08 1.42011428571429 0.415182290042184 0.825356303382564 GO:0017025 TBP-class protein binding 2/1050 25/18639 0.08 1.42011428571429 0.415182290042184 0.825356303382564 GO:0019211 phosphatase activator activity 2/1050 25/18639 0.08 1.42011428571429 0.415182290042184 0.825356303382564 GO:0042974 nuclear retinoic acid receptor binding 2/1050 25/18639 0.08 1.42011428571429 0.415182290042184 0.825356303382564 GO:0047617 fatty acyl-CoA hydrolase activity 2/1050 25/18639 0.08 1.42011428571429 0.415182290042184 0.825356303382564 GO:0120020 cholesterol transfer activity 2/1050 25/18639 0.08 1.42011428571429 0.415182290042184 0.825356303382564 GO:0015631 tubulin binding 23/1050 385/18639 0.0597402597402597 1.06047495361781 0.416103509727438 0.825356303382564 GO:0060589 nucleoside-triphosphatase regulator activity 29/1050 490/18639 0.0591836734693878 1.05059475218659 0.418815457137312 0.825356303382564 GO:0005319 lipid transporter activity 11/1050 178/18639 0.0617977528089888 1.09699839486356 0.420430384301423 0.825356303382564 GO:0004866 endopeptidase inhibitor activity 10/1050 161/18639 0.062111801242236 1.10257320319432 0.422013857054217 0.825356303382564 GO:0016859 cis-trans isomerase activity 3/1050 42/18639 0.0714285714285714 1.26795918367347 0.424241896726938 0.825356303382564 GO:0042056 chemoattractant activity 3/1050 42/18639 0.0714285714285714 1.26795918367347 0.424241896726938 0.825356303382564 GO:0045309 protein phosphorylated amino acid binding 4/1050 59/18639 0.0677966101694915 1.20348668280872 0.427023750369315 0.825356303382564 GO:0070063 RNA polymerase binding 4/1050 59/18639 0.0677966101694915 1.20348668280872 0.427023750369315 0.825356303382564 GO:0004175 endopeptidase activity 24/1050 405/18639 0.0592592592592593 1.05193650793651 0.428821527106753 0.825356303382564 GO:0001637 G protein-coupled chemoattractant receptor activity 2/1050 26/18639 0.0769230769230769 1.36549450549451 0.434927546831616 0.825356303382564 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/1050 26/18639 0.0769230769230769 1.36549450549451 0.434927546831616 0.825356303382564 GO:0004950 chemokine receptor activity 2/1050 26/18639 0.0769230769230769 1.36549450549451 0.434927546831616 0.825356303382564 GO:0005227 calcium-activated cation channel activity 2/1050 26/18639 0.0769230769230769 1.36549450549451 0.434927546831616 0.825356303382564 GO:0008143 poly(A) binding 2/1050 26/18639 0.0769230769230769 1.36549450549451 0.434927546831616 0.825356303382564 GO:0008198 ferrous iron binding 2/1050 26/18639 0.0769230769230769 1.36549450549451 0.434927546831616 0.825356303382564 GO:0015216 purine nucleotide transmembrane transporter activity 2/1050 26/18639 0.0769230769230769 1.36549450549451 0.434927546831616 0.825356303382564 GO:0016289 acyl-CoA hydrolase activity 2/1050 26/18639 0.0769230769230769 1.36549450549451 0.434927546831616 0.825356303382564 GO:0030507 spectrin binding 2/1050 26/18639 0.0769230769230769 1.36549450549451 0.434927546831616 0.825356303382564 GO:0034237 protein kinase A regulatory subunit binding 2/1050 26/18639 0.0769230769230769 1.36549450549451 0.434927546831616 0.825356303382564 GO:0050681 nuclear androgen receptor binding 2/1050 26/18639 0.0769230769230769 1.36549450549451 0.434927546831616 0.825356303382564 GO:0097602 cullin family protein binding 2/1050 26/18639 0.0769230769230769 1.36549450549451 0.434927546831616 0.825356303382564 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/1050 60/18639 0.0666666666666667 1.18342857142857 0.439777712246765 0.825356303382564 GO:0001094 TFIID-class transcription factor complex binding 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0004382 GDP phosphatase activity 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0004955 prostaglandin receptor activity 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0005031 tumor necrosis factor receptor activity 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0005131 growth hormone receptor binding 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0005528 FK506 binding 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0008239 dipeptidyl-peptidase activity 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0015203 polyamine transmembrane transporter activity 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0016427 tRNA (cytidine) methyltransferase activity 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0016868 intramolecular phosphotransferase activity 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0030957 Tat protein binding 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0031419 cobalamin binding 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0031434 mitogen-activated protein kinase kinase binding 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0035374 chondroitin sulfate binding 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0042975 peroxisome proliferator activated receptor binding 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0043121 neurotrophin binding 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0043295 glutathione binding 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0050308 sugar-phosphatase activity 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0098505 G-rich strand telomeric DNA binding 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0141109 transporter activator activity 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/1050 10/18639 0.1 1.77514285714286 0.440084111716978 0.825356303382564 GO:0004867 serine-type endopeptidase inhibitor activity 6/1050 95/18639 0.0631578947368421 1.12114285714286 0.447385204020213 0.837537345904507 GO:0016836 hydro-lyase activity 4/1050 61/18639 0.0655737704918033 1.1640281030445 0.452447093557148 0.837744514848524 GO:0016829 lyase activity 12/1050 200/18639 0.06 1.06508571428571 0.453576606340919 0.837744514848524 GO:0005385 zinc ion transmembrane transporter activity 2/1050 27/18639 0.0740740740740741 1.31492063492063 0.454306392419465 0.837744514848524 GO:0008320 protein transmembrane transporter activity 2/1050 27/18639 0.0740740740740741 1.31492063492063 0.454306392419465 0.837744514848524 GO:0035255 ionotropic glutamate receptor binding 2/1050 27/18639 0.0740740740740741 1.31492063492063 0.454306392419465 0.837744514848524 GO:0033293 monocarboxylic acid binding 5/1050 79/18639 0.0632911392405063 1.12350813743219 0.46108787005751 0.837744514848524 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0001851 complement component C3b binding 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0002162 dystroglycan binding 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0004954 prostanoid receptor activity 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0005114 type II transforming growth factor beta receptor binding 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0008199 ferric iron binding 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0008526 phosphatidylinositol transfer activity 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0010854 adenylate cyclase regulator activity 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0019203 carbohydrate phosphatase activity 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0043522 leucine zipper domain binding 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0140031 phosphorylation-dependent protein binding 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:1900750 oligopeptide binding 1/1050 11/18639 0.0909090909090909 1.61376623376623 0.471643061885918 0.837744514848524 GO:0016791 phosphatase activity 16/1050 273/18639 0.0586080586080586 1.04037676609105 0.472034873089034 0.837744514848524 GO:0051019 mitogen-activated protein kinase binding 2/1050 28/18639 0.0714285714285714 1.26795918367347 0.473297430429339 0.837744514848524 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/1050 28/18639 0.0714285714285714 1.26795918367347 0.473297430429339 0.837744514848524 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/1050 46/18639 0.0652173913043478 1.15770186335404 0.483873987889215 0.849886458155229 GO:0004536 DNA nuclease activity 4/1050 64/18639 0.0625 1.10946428571429 0.489847442548823 0.849886458155229 GO:0008017 microtubule binding 16/1050 276/18639 0.0579710144927536 1.02906832298137 0.489856446038208 0.849886458155229 GO:0004181 metallocarboxypeptidase activity 2/1050 29/18639 0.0689655172413793 1.22423645320197 0.49188283256286 0.849886458155229 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/1050 29/18639 0.0689655172413793 1.22423645320197 0.49188283256286 0.849886458155229 GO:0097472 cyclin-dependent protein kinase activity 2/1050 29/18639 0.0689655172413793 1.22423645320197 0.49188283256286 0.849886458155229 GO:0106222 lncRNA binding 2/1050 29/18639 0.0689655172413793 1.22423645320197 0.49188283256286 0.849886458155229 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0003720 telomerase activity 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0004000 adenosine deaminase activity 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0004032 aldose reductase (NADPH) activity 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0005049 nuclear export signal receptor activity 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0005078 MAP-kinase scaffold activity 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0005436 sodium:phosphate symporter activity 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0005527 macrolide binding 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0015368 calcium:monoatomic cation antiporter activity 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0016208 AMP binding 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0016423 tRNA (guanine) methyltransferase activity 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0035251 UDP-glucosyltransferase activity 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0043047 single-stranded telomeric DNA binding 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0045295 gamma-catenin binding 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0070410 co-SMAD binding 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0097677 STAT family protein binding 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:1990459 transferrin receptor binding 1/1050 12/18639 0.0833333333333333 1.47928571428571 0.501424830461169 0.849886458155229 GO:0051020 GTPase binding 18/1050 315/18639 0.0571428571428571 1.01436734693878 0.50995705227156 0.856979833027326 GO:0015215 nucleotide transmembrane transporter activity 2/1050 30/18639 0.0666666666666667 1.18342857142857 0.510048005157851 0.856979833027326 GO:0022839 monoatomic ion-gated channel activity 2/1050 30/18639 0.0666666666666667 1.18342857142857 0.510048005157851 0.856979833027326 GO:0031624 ubiquitin conjugating enzyme binding 2/1050 30/18639 0.0666666666666667 1.18342857142857 0.510048005157851 0.856979833027326 GO:0016500 protein-hormone receptor activity 4/1050 67/18639 0.0597014925373134 1.0597867803838 0.526150154225241 0.856979833027326 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/1050 67/18639 0.0597014925373134 1.0597867803838 0.526150154225241 0.856979833027326 GO:0005253 monoatomic anion channel activity 6/1050 103/18639 0.058252427184466 1.03406380027739 0.526285235950851 0.856979833027326 GO:0035254 glutamate receptor binding 3/1050 49/18639 0.0612244897959184 1.0868221574344 0.526588703650832 0.856979833027326 GO:0030295 protein kinase activator activity 8/1050 139/18639 0.0575539568345324 1.02166495375128 0.526979036417337 0.856979833027326 GO:0070851 growth factor receptor binding 8/1050 139/18639 0.0575539568345324 1.02166495375128 0.526979036417337 0.856979833027326 GO:0005164 tumor necrosis factor receptor binding 2/1050 31/18639 0.0645161290322581 1.1452534562212 0.527781281933863 0.856979833027326 GO:0016411 acylglycerol O-acyltransferase activity 2/1050 31/18639 0.0645161290322581 1.1452534562212 0.527781281933863 0.856979833027326 GO:0017147 Wnt-protein binding 2/1050 31/18639 0.0645161290322581 1.1452534562212 0.527781281933863 0.856979833027326 GO:0070273 phosphatidylinositol-4-phosphate binding 2/1050 31/18639 0.0645161290322581 1.1452534562212 0.527781281933863 0.856979833027326 GO:0072349 modified amino acid transmembrane transporter activity 2/1050 31/18639 0.0645161290322581 1.1452534562212 0.527781281933863 0.856979833027326 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/1050 13/18639 0.0769230769230769 1.36549450549451 0.529529405970687 0.856979833027326 GO:0003964 RNA-directed DNA polymerase activity 1/1050 13/18639 0.0769230769230769 1.36549450549451 0.529529405970687 0.856979833027326 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/1050 13/18639 0.0769230769230769 1.36549450549451 0.529529405970687 0.856979833027326 GO:0005035 death receptor activity 1/1050 13/18639 0.0769230769230769 1.36549450549451 0.529529405970687 0.856979833027326 GO:0008035 high-density lipoprotein particle binding 1/1050 13/18639 0.0769230769230769 1.36549450549451 0.529529405970687 0.856979833027326 GO:0019104 DNA N-glycosylase activity 1/1050 13/18639 0.0769230769230769 1.36549450549451 0.529529405970687 0.856979833027326 GO:0039706 co-receptor binding 1/1050 13/18639 0.0769230769230769 1.36549450549451 0.529529405970687 0.856979833027326 GO:0045159 myosin II binding 1/1050 13/18639 0.0769230769230769 1.36549450549451 0.529529405970687 0.856979833027326 GO:0051011 microtubule minus-end binding 1/1050 13/18639 0.0769230769230769 1.36549450549451 0.529529405970687 0.856979833027326 GO:0070700 BMP receptor binding 1/1050 13/18639 0.0769230769230769 1.36549450549451 0.529529405970687 0.856979833027326 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/1050 13/18639 0.0769230769230769 1.36549450549451 0.529529405970687 0.856979833027326 GO:0089720 caspase binding 1/1050 13/18639 0.0769230769230769 1.36549450549451 0.529529405970687 0.856979833027326 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/1050 13/18639 0.0769230769230769 1.36549450549451 0.529529405970687 0.856979833027326 GO:1901338 catecholamine binding 1/1050 13/18639 0.0769230769230769 1.36549450549451 0.529529405970687 0.856979833027326 GO:0031267 small GTPase binding 16/1050 283/18639 0.0565371024734982 1.00361433619384 0.530954297565097 0.857949479269262 GO:0035091 phosphatidylinositol binding 16/1050 284/18639 0.0563380281690141 1.00008048289738 0.536752695681163 0.865972128591194 GO:1990841 promoter-specific chromatin binding 4/1050 68/18639 0.0588235294117647 1.04420168067227 0.537971161228164 0.866592304676066 GO:0015605 organophosphate ester transmembrane transporter activity 3/1050 50/18639 0.06 1.06508571428571 0.540385884457592 0.867473200469482 GO:0032813 tumor necrosis factor receptor superfamily binding 3/1050 50/18639 0.06 1.06508571428571 0.540385884457592 0.867473200469482 GO:0015106 bicarbonate transmembrane transporter activity 2/1050 32/18639 0.0625 1.10946428571429 0.545073641037097 0.867473200469482 GO:0120015 sterol transfer activity 2/1050 32/18639 0.0625 1.10946428571429 0.545073641037097 0.867473200469482 GO:0140142 nucleocytoplasmic carrier activity 2/1050 32/18639 0.0625 1.10946428571429 0.545073641037097 0.867473200469482 GO:0002039 p53 binding 4/1050 69/18639 0.0579710144927536 1.02906832298137 0.549641212586472 0.867473200469482 GO:0008013 beta-catenin binding 6/1050 106/18639 0.0566037735849057 1.00479784366577 0.554700443875317 0.867473200469482 GO:0004705 JUN kinase activity 1/1050 14/18639 0.0714285714285714 1.26795918367347 0.556051156412584 0.867473200469482 GO:0005313 L-glutamate transmembrane transporter activity 1/1050 14/18639 0.0714285714285714 1.26795918367347 0.556051156412584 0.867473200469482 GO:0005347 ATP transmembrane transporter activity 1/1050 14/18639 0.0714285714285714 1.26795918367347 0.556051156412584 0.867473200469482 GO:0005545 1-phosphatidylinositol binding 1/1050 14/18639 0.0714285714285714 1.26795918367347 0.556051156412584 0.867473200469482 GO:0008191 metalloendopeptidase inhibitor activity 1/1050 14/18639 0.0714285714285714 1.26795918367347 0.556051156412584 0.867473200469482 GO:0008474 palmitoyl-(protein) hydrolase activity 1/1050 14/18639 0.0714285714285714 1.26795918367347 0.556051156412584 0.867473200469482 GO:0008559 ABC-type xenobiotic transporter activity 1/1050 14/18639 0.0714285714285714 1.26795918367347 0.556051156412584 0.867473200469482 GO:0015926 glucosidase activity 1/1050 14/18639 0.0714285714285714 1.26795918367347 0.556051156412584 0.867473200469482 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/1050 14/18639 0.0714285714285714 1.26795918367347 0.556051156412584 0.867473200469482 GO:0034236 protein kinase A catalytic subunit binding 1/1050 14/18639 0.0714285714285714 1.26795918367347 0.556051156412584 0.867473200469482 GO:0043176 amine binding 1/1050 14/18639 0.0714285714285714 1.26795918367347 0.556051156412584 0.867473200469482 GO:0044548 S100 protein binding 1/1050 14/18639 0.0714285714285714 1.26795918367347 0.556051156412584 0.867473200469482 GO:0098599 palmitoyl hydrolase activity 1/1050 14/18639 0.0714285714285714 1.26795918367347 0.556051156412584 0.867473200469482 GO:1901474 azole transmembrane transporter activity 1/1050 14/18639 0.0714285714285714 1.26795918367347 0.556051156412584 0.867473200469482 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/1050 33/18639 0.0606060606060606 1.07584415584416 0.561918444626101 0.872695461833361 GO:0030296 protein tyrosine kinase activator activity 2/1050 33/18639 0.0606060606060606 1.07584415584416 0.561918444626101 0.872695461833361 GO:0071889 14-3-3 protein binding 2/1050 33/18639 0.0606060606060606 1.07584415584416 0.561918444626101 0.872695461833361 GO:0003727 single-stranded RNA binding 5/1050 89/18639 0.0561797752808989 0.997271268057785 0.567474738700909 0.876257230132982 GO:0008175 tRNA methyltransferase activity 2/1050 34/18639 0.0588235294117647 1.04420168067227 0.578311199360324 0.876257230132982 GO:0030332 cyclin binding 2/1050 34/18639 0.0588235294117647 1.04420168067227 0.578311199360324 0.876257230132982 GO:0090482 vitamin transmembrane transporter activity 2/1050 34/18639 0.0588235294117647 1.04420168067227 0.578311199360324 0.876257230132982 GO:0004864 protein phosphatase inhibitor activity 3/1050 53/18639 0.0566037735849057 1.00479784366577 0.580342988591249 0.876257230132982 GO:0005544 calcium-dependent phospholipid binding 3/1050 53/18639 0.0566037735849057 1.00479784366577 0.580342988591249 0.876257230132982 GO:0008146 sulfotransferase activity 3/1050 53/18639 0.0566037735849057 1.00479784366577 0.580342988591249 0.876257230132982 GO:0017046 peptide hormone binding 3/1050 53/18639 0.0566037735849057 1.00479784366577 0.580342988591249 0.876257230132982 GO:0140296 general transcription initiation factor binding 3/1050 53/18639 0.0566037735849057 1.00479784366577 0.580342988591249 0.876257230132982 GO:1901505 carbohydrate derivative transmembrane transporter activity 3/1050 53/18639 0.0566037735849057 1.00479784366577 0.580342988591249 0.876257230132982 GO:0000774 adenyl-nucleotide exchange factor activity 1/1050 15/18639 0.0666666666666667 1.18342857142857 0.581079144910129 0.876257230132982 GO:0004129 cytochrome-c oxidase activity 1/1050 15/18639 0.0666666666666667 1.18342857142857 0.581079144910129 0.876257230132982 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/1050 15/18639 0.0666666666666667 1.18342857142857 0.581079144910129 0.876257230132982 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/1050 15/18639 0.0666666666666667 1.18342857142857 0.581079144910129 0.876257230132982 GO:0015929 hexosaminidase activity 1/1050 15/18639 0.0666666666666667 1.18342857142857 0.581079144910129 0.876257230132982 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/1050 15/18639 0.0666666666666667 1.18342857142857 0.581079144910129 0.876257230132982 GO:0017081 chloride channel regulator activity 1/1050 15/18639 0.0666666666666667 1.18342857142857 0.581079144910129 0.876257230132982 GO:0048531 beta-1,3-galactosyltransferase activity 1/1050 15/18639 0.0666666666666667 1.18342857142857 0.581079144910129 0.876257230132982 GO:0141050 histone H3K deacetylase activity 1/1050 15/18639 0.0666666666666667 1.18342857142857 0.581079144910129 0.876257230132982 GO:0141051 histone H4K deacetylase activity 1/1050 15/18639 0.0666666666666667 1.18342857142857 0.581079144910129 0.876257230132982 GO:1901681 sulfur compound binding 15/1050 275/18639 0.0545454545454545 0.96825974025974 0.589140399342347 0.882328073671506 GO:0022804 active transmembrane transporter activity 25/1050 457/18639 0.0547045951859956 0.971084713973117 0.590266874388917 0.882328073671506 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/1050 54/18639 0.0555555555555556 0.986190476190476 0.593163820338193 0.882328073671506 GO:0050661 NADP binding 3/1050 54/18639 0.0555555555555556 0.986190476190476 0.593163820338193 0.882328073671506 GO:0000175 3'-5'-RNA exonuclease activity 2/1050 35/18639 0.0571428571428571 1.01436734693878 0.594249336266399 0.882328073671506 GO:0061631 ubiquitin conjugating enzyme activity 2/1050 35/18639 0.0571428571428571 1.01436734693878 0.594249336266399 0.882328073671506 GO:1902936 phosphatidylinositol bisphosphate binding 6/1050 111/18639 0.0540540540540541 0.95953667953668 0.600213097021294 0.882328073671506 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/1050 16/18639 0.0625 1.10946428571429 0.604697427655209 0.882328073671506 GO:0004707 MAP kinase activity 1/1050 16/18639 0.0625 1.10946428571429 0.604697427655209 0.882328073671506 GO:0005149 interleukin-1 receptor binding 1/1050 16/18639 0.0625 1.10946428571429 0.604697427655209 0.882328073671506 GO:0005159 insulin-like growth factor receptor binding 1/1050 16/18639 0.0625 1.10946428571429 0.604697427655209 0.882328073671506 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/1050 16/18639 0.0625 1.10946428571429 0.604697427655209 0.882328073671506 GO:0005521 lamin binding 1/1050 16/18639 0.0625 1.10946428571429 0.604697427655209 0.882328073671506 GO:0008296 3'-5'-DNA exonuclease activity 1/1050 16/18639 0.0625 1.10946428571429 0.604697427655209 0.882328073671506 GO:0015562 efflux transmembrane transporter activity 1/1050 16/18639 0.0625 1.10946428571429 0.604697427655209 0.882328073671506 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/1050 16/18639 0.0625 1.10946428571429 0.604697427655209 0.882328073671506 GO:0017070 U6 snRNA binding 1/1050 16/18639 0.0625 1.10946428571429 0.604697427655209 0.882328073671506 GO:0030275 LRR domain binding 1/1050 16/18639 0.0625 1.10946428571429 0.604697427655209 0.882328073671506 GO:0034450 ubiquitin-ubiquitin ligase activity 1/1050 16/18639 0.0625 1.10946428571429 0.604697427655209 0.882328073671506 GO:0043023 ribosomal large subunit binding 1/1050 16/18639 0.0625 1.10946428571429 0.604697427655209 0.882328073671506 GO:0070411 I-SMAD binding 1/1050 16/18639 0.0625 1.10946428571429 0.604697427655209 0.882328073671506 GO:0140327 flippase activity 1/1050 16/18639 0.0625 1.10946428571429 0.604697427655209 0.882328073671506 GO:0008374 O-acyltransferase activity 3/1050 55/18639 0.0545454545454545 0.96825974025974 0.605727710104142 0.882328073671506 GO:0098632 cell-cell adhesion mediator activity 3/1050 55/18639 0.0545454545454545 0.96825974025974 0.605727710104142 0.882328073671506 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/1050 36/18639 0.0555555555555556 0.986190476190476 0.609732008562215 0.882328073671506 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/1050 36/18639 0.0555555555555556 0.986190476190476 0.609732008562215 0.882328073671506 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/1050 36/18639 0.0555555555555556 0.986190476190476 0.609732008562215 0.882328073671506 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/1050 36/18639 0.0555555555555556 0.986190476190476 0.609732008562215 0.882328073671506 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/1050 36/18639 0.0555555555555556 0.986190476190476 0.609732008562215 0.882328073671506 GO:0031406 carboxylic acid binding 10/1050 187/18639 0.053475935828877 0.949274255156608 0.613037835519067 0.882706996210517 GO:0019212 phosphatase inhibitor activity 3/1050 56/18639 0.0535714285714286 0.950969387755102 0.618031163892142 0.882706996210517 GO:0003730 mRNA 3'-UTR binding 14/1050 262/18639 0.0534351145038168 0.948549618320611 0.619696295407926 0.882706996210517 GO:0022829 wide pore channel activity 2/1050 37/18639 0.0540540540540541 0.95953667953668 0.624759906117156 0.882706996210517 GO:0043177 organic acid binding 10/1050 189/18639 0.0529100529100529 0.939229024943311 0.626476967998526 0.882706996210517 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/1050 17/18639 0.0588235294117647 1.04420168067227 0.626985335133168 0.882706996210517 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/1050 17/18639 0.0588235294117647 1.04420168067227 0.626985335133168 0.882706996210517 GO:0004549 tRNA-specific ribonuclease activity 1/1050 17/18639 0.0588235294117647 1.04420168067227 0.626985335133168 0.882706996210517 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/1050 17/18639 0.0588235294117647 1.04420168067227 0.626985335133168 0.882706996210517 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/1050 17/18639 0.0588235294117647 1.04420168067227 0.626985335133168 0.882706996210517 GO:0008484 sulfuric ester hydrolase activity 1/1050 17/18639 0.0588235294117647 1.04420168067227 0.626985335133168 0.882706996210517 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/1050 17/18639 0.0588235294117647 1.04420168067227 0.626985335133168 0.882706996210517 GO:0016018 cyclosporin A binding 1/1050 17/18639 0.0588235294117647 1.04420168067227 0.626985335133168 0.882706996210517 GO:0017110 nucleoside diphosphate phosphatase activity 1/1050 17/18639 0.0588235294117647 1.04420168067227 0.626985335133168 0.882706996210517 GO:0019198 transmembrane receptor protein phosphatase activity 1/1050 17/18639 0.0588235294117647 1.04420168067227 0.626985335133168 0.882706996210517 GO:0031489 myosin V binding 1/1050 17/18639 0.0588235294117647 1.04420168067227 0.626985335133168 0.882706996210517 GO:0045125 bioactive lipid receptor activity 1/1050 17/18639 0.0588235294117647 1.04420168067227 0.626985335133168 0.882706996210517 GO:0045236 CXCR chemokine receptor binding 1/1050 17/18639 0.0588235294117647 1.04420168067227 0.626985335133168 0.882706996210517 GO:0070402 NADPH binding 1/1050 17/18639 0.0588235294117647 1.04420168067227 0.626985335133168 0.882706996210517 GO:1990226 histone methyltransferase binding 1/1050 17/18639 0.0588235294117647 1.04420168067227 0.626985335133168 0.882706996210517 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 26/1050 484/18639 0.0537190082644628 0.953589138134593 0.628436884301523 0.88329751317166 GO:0046906 tetrapyrrole binding 8/1050 152/18639 0.0526315789473684 0.934285714285714 0.629105062316678 0.88329751317166 GO:0005109 frizzled binding 2/1050 38/18639 0.0526315789473684 0.934285714285714 0.639335085318525 0.894036545956861 GO:0005501 retinoid binding 2/1050 38/18639 0.0526315789473684 0.934285714285714 0.639335085318525 0.894036545956861 GO:0019840 isoprenoid binding 2/1050 38/18639 0.0526315789473684 0.934285714285714 0.639335085318525 0.894036545956861 GO:0000400 four-way junction DNA binding 1/1050 18/18639 0.0555555555555556 0.986190476190476 0.648017737566321 0.896525205501209 GO:0000900 mRNA regulatory element binding translation repressor activity 1/1050 18/18639 0.0555555555555556 0.986190476190476 0.648017737566321 0.896525205501209 GO:0008308 voltage-gated monoatomic anion channel activity 1/1050 18/18639 0.0555555555555556 0.986190476190476 0.648017737566321 0.896525205501209 GO:0008525 phosphatidylcholine transporter activity 1/1050 18/18639 0.0555555555555556 0.986190476190476 0.648017737566321 0.896525205501209 GO:0015172 acidic amino acid transmembrane transporter activity 1/1050 18/18639 0.0555555555555556 0.986190476190476 0.648017737566321 0.896525205501209 GO:0034185 apolipoprotein binding 1/1050 18/18639 0.0555555555555556 0.986190476190476 0.648017737566321 0.896525205501209 GO:0035615 clathrin adaptor activity 1/1050 18/18639 0.0555555555555556 0.986190476190476 0.648017737566321 0.896525205501209 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/1050 18/18639 0.0555555555555556 0.986190476190476 0.648017737566321 0.896525205501209 GO:0000287 magnesium ion binding 12/1050 230/18639 0.0521739130434783 0.92616149068323 0.649489149690101 0.897365992723423 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/1050 39/18639 0.0512820512820513 0.91032967032967 0.653460813199796 0.900458600682477 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/1050 39/18639 0.0512820512820513 0.91032967032967 0.653460813199796 0.900458600682477 GO:0016835 carbon-oxygen lyase activity 4/1050 79/18639 0.0506329113924051 0.898806509945751 0.657000170477543 0.901184470108958 GO:0001216 DNA-binding transcription activator activity 26/1050 491/18639 0.0529531568228106 0.939994180971778 0.657378986623102 0.901184470108958 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 3/1050 60/18639 0.05 0.887571428571429 0.664595702089758 0.901184470108958 GO:0004252 serine-type endopeptidase activity 9/1050 176/18639 0.0511363636363636 0.907743506493507 0.66491013492419 0.901184470108958 GO:0004177 aminopeptidase activity 2/1050 40/18639 0.05 0.887571428571429 0.667141424766165 0.901184470108958 GO:0030331 nuclear estrogen receptor binding 2/1050 40/18639 0.05 0.887571428571429 0.667141424766165 0.901184470108958 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/1050 19/18639 0.0526315789473684 0.934285714285714 0.667865295460922 0.901184470108958 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/1050 19/18639 0.0526315789473684 0.934285714285714 0.667865295460922 0.901184470108958 GO:0008381 mechanosensitive monoatomic ion channel activity 1/1050 19/18639 0.0526315789473684 0.934285714285714 0.667865295460922 0.901184470108958 GO:0008574 plus-end-directed microtubule motor activity 1/1050 19/18639 0.0526315789473684 0.934285714285714 0.667865295460922 0.901184470108958 GO:0015245 fatty acid transmembrane transporter activity 1/1050 19/18639 0.0526315789473684 0.934285714285714 0.667865295460922 0.901184470108958 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/1050 19/18639 0.0526315789473684 0.934285714285714 0.667865295460922 0.901184470108958 GO:0022840 leak channel activity 1/1050 19/18639 0.0526315789473684 0.934285714285714 0.667865295460922 0.901184470108958 GO:0022842 narrow pore channel activity 1/1050 19/18639 0.0526315789473684 0.934285714285714 0.667865295460922 0.901184470108958 GO:0042577 lipid phosphatase activity 1/1050 19/18639 0.0526315789473684 0.934285714285714 0.667865295460922 0.901184470108958 GO:0046527 glucosyltransferase activity 1/1050 19/18639 0.0526315789473684 0.934285714285714 0.667865295460922 0.901184470108958 GO:0005096 GTPase activator activity 14/1050 271/18639 0.0516605166051661 0.917047970479705 0.669395779832192 0.902078100188907 GO:0003712 transcription coregulator activity 26/1050 495/18639 0.0525252525252525 0.932398268398268 0.67340570757447 0.906306386230408 GO:0008227 G protein-coupled amine receptor activity 2/1050 41/18639 0.0487804878048781 0.865923344947735 0.680382192527396 0.913329584025794 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/1050 41/18639 0.0487804878048781 0.865923344947735 0.680382192527396 0.913329584025794 GO:0010851 cyclase regulator activity 1/1050 20/18639 0.05 0.887571428571429 0.686594696092825 0.914579345180058 GO:0015095 magnesium ion transmembrane transporter activity 1/1050 20/18639 0.05 0.887571428571429 0.686594696092825 0.914579345180058 GO:0016408 C-acyltransferase activity 1/1050 20/18639 0.05 0.887571428571429 0.686594696092825 0.914579345180058 GO:0016505 peptidase activator activity involved in apoptotic process 1/1050 20/18639 0.05 0.887571428571429 0.686594696092825 0.914579345180058 GO:0052745 inositol phosphate phosphatase activity 1/1050 20/18639 0.05 0.887571428571429 0.686594696092825 0.914579345180058 GO:0061608 nuclear import signal receptor activity 1/1050 20/18639 0.05 0.887571428571429 0.686594696092825 0.914579345180058 GO:0004520 DNA endonuclease activity 2/1050 42/18639 0.0476190476190476 0.84530612244898 0.69318920731742 0.919825780846486 GO:0048487 beta-tubulin binding 2/1050 42/18639 0.0476190476190476 0.84530612244898 0.69318920731742 0.919825780846486 GO:0051879 Hsp90 protein binding 2/1050 42/18639 0.0476190476190476 0.84530612244898 0.69318920731742 0.919825780846486 GO:0020037 heme binding 7/1050 142/18639 0.0492957746478873 0.875070422535211 0.694572231414296 0.92048539341767 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/1050 21/18639 0.0476190476190476 0.84530612244898 0.704268876720277 0.925076312152172 GO:0005123 death receptor binding 1/1050 21/18639 0.0476190476190476 0.84530612244898 0.704268876720277 0.925076312152172 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/1050 21/18639 0.0476190476190476 0.84530612244898 0.704268876720277 0.925076312152172 GO:0010314 phosphatidylinositol-5-phosphate binding 1/1050 21/18639 0.0476190476190476 0.84530612244898 0.704268876720277 0.925076312152172 GO:0015125 bile acid transmembrane transporter activity 1/1050 21/18639 0.0476190476190476 0.84530612244898 0.704268876720277 0.925076312152172 GO:0036122 BMP binding 1/1050 21/18639 0.0476190476190476 0.84530612244898 0.704268876720277 0.925076312152172 GO:0140312 cargo adaptor activity 1/1050 21/18639 0.0476190476190476 0.84530612244898 0.704268876720277 0.925076312152172 GO:0008237 metallopeptidase activity 9/1050 184/18639 0.0489130434782609 0.868276397515528 0.71515827844113 0.933847730881788 GO:0160215 deacylase activity 3/1050 65/18639 0.0461538461538462 0.819296703296703 0.716797617906857 0.933847730881788 GO:0016790 thiolester hydrolase activity 2/1050 44/18639 0.0454545454545455 0.806883116883117 0.717529790080271 0.933847730881788 GO:0004407 histone deacetylase activity 1/1050 22/18639 0.0454545454545455 0.806883116883117 0.720947235268118 0.933847730881788 GO:0008093 cytoskeletal anchor activity 1/1050 22/18639 0.0454545454545455 0.806883116883117 0.720947235268118 0.933847730881788 GO:0016881 acid-amino acid ligase activity 1/1050 22/18639 0.0454545454545455 0.806883116883117 0.720947235268118 0.933847730881788 GO:0033558 protein lysine deacetylase activity 1/1050 22/18639 0.0454545454545455 0.806883116883117 0.720947235268118 0.933847730881788 GO:0050321 tau-protein kinase activity 1/1050 22/18639 0.0454545454545455 0.806883116883117 0.720947235268118 0.933847730881788 GO:0070034 telomerase RNA binding 1/1050 22/18639 0.0454545454545455 0.806883116883117 0.720947235268118 0.933847730881788 GO:0140517 protein-RNA adaptor activity 1/1050 22/18639 0.0454545454545455 0.806883116883117 0.720947235268118 0.933847730881788 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/1050 86/18639 0.0465116279069767 0.825647840531561 0.721089391591412 0.933847730881788 GO:0015293 symporter activity 7/1050 146/18639 0.0479452054794521 0.851095890410959 0.721732173145405 0.933847730881788 GO:0000295 adenine nucleotide transmembrane transporter activity 1/1050 23/18639 0.0434782608695652 0.771801242236025 0.736685829185961 0.944958736449646 GO:0005283 amino acid:sodium symporter activity 1/1050 23/18639 0.0434782608695652 0.771801242236025 0.736685829185961 0.944958736449646 GO:0008171 O-methyltransferase activity 1/1050 23/18639 0.0434782608695652 0.771801242236025 0.736685829185961 0.944958736449646 GO:0016849 phosphorus-oxygen lyase activity 1/1050 23/18639 0.0434782608695652 0.771801242236025 0.736685829185961 0.944958736449646 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/1050 23/18639 0.0434782608695652 0.771801242236025 0.736685829185961 0.944958736449646 GO:0099186 structural constituent of postsynapse 1/1050 23/18639 0.0434782608695652 0.771801242236025 0.736685829185961 0.944958736449646 GO:0140103 catalytic activity, acting on a glycoprotein 1/1050 23/18639 0.0434782608695652 0.771801242236025 0.736685829185961 0.944958736449646 GO:0008509 monoatomic anion transmembrane transporter activity 7/1050 149/18639 0.0469798657718121 0.833959731543624 0.740992617875071 0.949311134367693 GO:0016757 glycosyltransferase activity 13/1050 267/18639 0.048689138576779 0.86430176565008 0.744835321600207 0.951446062764167 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 6/1050 130/18639 0.0461538461538462 0.819296703296703 0.747404181990205 0.951446062764167 GO:0099095 ligand-gated monoatomic anion channel activity 2/1050 47/18639 0.0425531914893617 0.755379939209726 0.750975529442129 0.951446062764167 GO:0140938 histone H3 methyltransferase activity 2/1050 47/18639 0.0425531914893617 0.755379939209726 0.750975529442129 0.951446062764167 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/1050 24/18639 0.0416666666666667 0.739642857142857 0.751537563143564 0.951446062764167 GO:0005315 phosphate transmembrane transporter activity 1/1050 24/18639 0.0416666666666667 0.739642857142857 0.751537563143564 0.951446062764167 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/1050 24/18639 0.0416666666666667 0.739642857142857 0.751537563143564 0.951446062764167 GO:0030552 cAMP binding 1/1050 24/18639 0.0416666666666667 0.739642857142857 0.751537563143564 0.951446062764167 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/1050 24/18639 0.0416666666666667 0.739642857142857 0.751537563143564 0.951446062764167 GO:0005085 guanyl-nucleotide exchange factor activity 11/1050 230/18639 0.0478260869565217 0.848981366459627 0.753609585278103 0.951446062764167 GO:0008080 N-acetyltransferase activity 3/1050 69/18639 0.0434782608695652 0.771801242236025 0.753845325639719 0.951446062764167 GO:0008201 heparin binding 8/1050 172/18639 0.0465116279069767 0.825647840531561 0.75938670956802 0.951446062764167 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/1050 48/18639 0.0416666666666667 0.739642857142857 0.761341211562703 0.951446062764167 GO:0032266 phosphatidylinositol-3-phosphate binding 2/1050 48/18639 0.0416666666666667 0.739642857142857 0.761341211562703 0.951446062764167 GO:0140693 molecular condensate scaffold activity 2/1050 48/18639 0.0416666666666667 0.739642857142857 0.761341211562703 0.951446062764167 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/1050 70/18639 0.0428571428571429 0.760775510204082 0.762473273155047 0.951446062764167 GO:0016782 transferase activity, transferring sulphur-containing groups 3/1050 70/18639 0.0428571428571429 0.760775510204082 0.762473273155047 0.951446062764167 GO:0000030 mannosyltransferase activity 1/1050 25/18639 0.04 0.710057142857143 0.765552366189455 0.951446062764167 GO:0008483 transaminase activity 1/1050 25/18639 0.04 0.710057142857143 0.765552366189455 0.951446062764167 GO:0015662 P-type ion transporter activity 1/1050 25/18639 0.04 0.710057142857143 0.765552366189455 0.951446062764167 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/1050 25/18639 0.04 0.710057142857143 0.765552366189455 0.951446062764167 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/1050 25/18639 0.04 0.710057142857143 0.765552366189455 0.951446062764167 GO:0019707 protein-cysteine S-acyltransferase activity 1/1050 25/18639 0.04 0.710057142857143 0.765552366189455 0.951446062764167 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/1050 25/18639 0.04 0.710057142857143 0.765552366189455 0.951446062764167 GO:0140358 P-type transmembrane transporter activity 1/1050 25/18639 0.04 0.710057142857143 0.765552366189455 0.951446062764167 GO:0016763 pentosyltransferase activity 2/1050 49/18639 0.0408163265306122 0.724548104956268 0.771330679984485 0.957482170255531 GO:0022832 voltage-gated channel activity 8/1050 175/18639 0.0457142857142857 0.81149387755102 0.775777686272571 0.960985363376907 GO:0052742 phosphatidylinositol kinase activity 1/1050 26/18639 0.0384615384615385 0.682747252747253 0.778777358963768 0.960985363376907 GO:0070006 metalloaminopeptidase activity 1/1050 26/18639 0.0384615384615385 0.682747252747253 0.778777358963768 0.960985363376907 GO:0070412 R-SMAD binding 1/1050 26/18639 0.0384615384615385 0.682747252747253 0.778777358963768 0.960985363376907 GO:0120014 phospholipid transfer activity 1/1050 26/18639 0.0384615384615385 0.682747252747253 0.778777358963768 0.960985363376907 GO:0016758 hexosyltransferase activity 9/1050 197/18639 0.0456852791878173 0.81097897026831 0.785734889674339 0.964924923676723 GO:0015294 solute:monoatomic cation symporter activity 5/1050 116/18639 0.0431034482758621 0.765147783251232 0.78911809686849 0.964924923676723 GO:0008276 protein methyltransferase activity 4/1050 95/18639 0.0421052631578947 0.747428571428571 0.789851827257813 0.964924923676723 GO:0005048 signal sequence binding 2/1050 51/18639 0.0392156862745098 0.696134453781513 0.790218886688329 0.964924923676723 GO:0016597 amino acid binding 2/1050 51/18639 0.0392156862745098 0.696134453781513 0.790218886688329 0.964924923676723 GO:0005104 fibroblast growth factor receptor binding 1/1050 27/18639 0.037037037037037 0.657460317460317 0.791257011523165 0.964924923676723 GO:0008266 poly(U) RNA binding 1/1050 27/18639 0.037037037037037 0.657460317460317 0.791257011523165 0.964924923676723 GO:0008395 steroid hydroxylase activity 1/1050 27/18639 0.037037037037037 0.657460317460317 0.791257011523165 0.964924923676723 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/1050 27/18639 0.037037037037037 0.657460317460317 0.791257011523165 0.964924923676723 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/1050 27/18639 0.037037037037037 0.657460317460317 0.791257011523165 0.964924923676723 GO:0016407 acetyltransferase activity 4/1050 96/18639 0.0416666666666667 0.739642857142857 0.796581055583539 0.970278683178542 GO:0003725 double-stranded RNA binding 3/1050 75/18639 0.04 0.710057142857143 0.801983783217016 0.972437751403601 GO:0016866 intramolecular transferase activity 1/1050 28/18639 0.0357142857142857 0.633979591836735 0.803033292304418 0.972437751403601 GO:0046966 nuclear thyroid hormone receptor binding 1/1050 28/18639 0.0357142857142857 0.633979591836735 0.803033292304418 0.972437751403601 GO:0051959 dynein light intermediate chain binding 1/1050 28/18639 0.0357142857142857 0.633979591836735 0.803033292304418 0.972437751403601 GO:0097718 disordered domain specific binding 1/1050 28/18639 0.0357142857142857 0.633979591836735 0.803033292304418 0.972437751403601 GO:0016251 RNA polymerase II general transcription initiation factor activity 2/1050 53/18639 0.0377358490566038 0.669865229110512 0.807717014210251 0.976970870505764 GO:0042626 ATPase-coupled transmembrane transporter activity 4/1050 98/18639 0.0408163265306122 0.724548104956268 0.809517613269197 0.977845275055843 GO:0008083 growth factor activity 7/1050 162/18639 0.0432098765432099 0.767037037037037 0.8135085162084 0.977845275055843 GO:0004629 phospholipase C activity 1/1050 29/18639 0.0344827586206897 0.612118226600985 0.814145808723759 0.977845275055843 GO:0005416 amino acid:monoatomic cation symporter activity 1/1050 29/18639 0.0344827586206897 0.612118226600985 0.814145808723759 0.977845275055843 GO:0016417 S-acyltransferase activity 1/1050 29/18639 0.0344827586206897 0.612118226600985 0.814145808723759 0.977845275055843 GO:0035250 UDP-galactosyltransferase activity 1/1050 29/18639 0.0344827586206897 0.612118226600985 0.814145808723759 0.977845275055843 GO:0017069 snRNA binding 2/1050 54/18639 0.037037037037037 0.657460317460317 0.815969060128408 0.977845275055843 GO:0140463 chromatin-protein adaptor activity 2/1050 54/18639 0.037037037037037 0.657460317460317 0.815969060128408 0.977845275055843 GO:0043130 ubiquitin binding 4/1050 100/18639 0.04 0.710057142857143 0.821774738214877 0.97919152632751 GO:0008187 poly-pyrimidine tract binding 1/1050 30/18639 0.0333333333333333 0.591714285714286 0.824631939881204 0.97919152632751 GO:0016769 transferase activity, transferring nitrogenous groups 1/1050 30/18639 0.0333333333333333 0.591714285714286 0.824631939881204 0.97919152632751 GO:0031210 phosphatidylcholine binding 1/1050 30/18639 0.0333333333333333 0.591714285714286 0.824631939881204 0.97919152632751 GO:0033612 receptor serine/threonine kinase binding 1/1050 30/18639 0.0333333333333333 0.591714285714286 0.824631939881204 0.97919152632751 GO:0048019 receptor antagonist activity 1/1050 30/18639 0.0333333333333333 0.591714285714286 0.824631939881204 0.97919152632751 GO:0051721 protein phosphatase 2A binding 1/1050 30/18639 0.0333333333333333 0.591714285714286 0.824631939881204 0.97919152632751 GO:0098918 structural constituent of synapse 1/1050 30/18639 0.0333333333333333 0.591714285714286 0.824631939881204 0.97919152632751 GO:0015370 solute:sodium symporter activity 3/1050 79/18639 0.0379746835443038 0.674104882459313 0.82948335700328 0.983827862929689 GO:0005516 calmodulin binding 9/1050 207/18639 0.0434782608695652 0.771801242236025 0.830677828662002 0.984005857256352 GO:0030170 pyridoxal phosphate binding 2/1050 56/18639 0.0357142857142857 0.633979591836735 0.831527567537129 0.984005857256352 GO:0008194 UDP-glycosyltransferase activity 6/1050 145/18639 0.0413793103448276 0.734541871921182 0.832584487655238 0.98413570270056 GO:0005452 solute:inorganic anion antiporter activity 1/1050 31/18639 0.032258064516129 0.572626728110599 0.834526961812782 0.985310810594864 GO:0000049 tRNA binding 3/1050 80/18639 0.0375 0.665678571428571 0.835824387943212 0.985722518811574 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 10/1050 229/18639 0.0436681222707424 0.775171553337492 0.836779700778937 0.985730282436866 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/1050 57/18639 0.0350877192982456 0.622857142857143 0.838853245332406 0.985937241968744 GO:0070279 vitamin B6 binding 2/1050 57/18639 0.0350877192982456 0.622857142857143 0.838853245332406 0.985937241968744 GO:0015101 organic cation transmembrane transporter activity 3/1050 81/18639 0.037037037037037 0.657460317460317 0.841961109711769 0.986248445637136 GO:0015085 calcium ion transmembrane transporter activity 6/1050 147/18639 0.0408163265306122 0.724548104956268 0.841976871044587 0.986248445637136 GO:0046873 metal ion transmembrane transporter activity 21/1050 450/18639 0.0466666666666667 0.8284 0.842633161846718 0.986248445637136 GO:0008378 galactosyltransferase activity 1/1050 32/18639 0.03125 0.554732142857143 0.843864165708772 0.986248445637136 GO:0031369 translation initiation factor binding 1/1050 32/18639 0.03125 0.554732142857143 0.843864165708772 0.986248445637136 GO:0061980 regulatory RNA binding 2/1050 58/18639 0.0344827586206897 0.612118226600985 0.845889202522502 0.987504361147056 GO:0019783 ubiquitin-like protein peptidase activity 5/1050 127/18639 0.0393700787401575 0.698875140607424 0.849257948395824 0.990324364066511 GO:0031593 polyubiquitin modification-dependent protein binding 2/1050 59/18639 0.0338983050847458 0.601743341404358 0.852644795502323 0.991449790402428 GO:0019239 deaminase activity 1/1050 33/18639 0.0303030303030303 0.537922077922078 0.852674969492605 0.991449790402428 GO:0031490 chromatin DNA binding 5/1050 128/18639 0.0390625 0.693415178571429 0.853943867305885 0.991449790402428 GO:0001098 basal transcription machinery binding 2/1050 60/18639 0.0333333333333333 0.591714285714286 0.859129246999308 0.991449790402428 GO:0001099 basal RNA polymerase II transcription machinery binding 2/1050 60/18639 0.0333333333333333 0.591714285714286 0.859129246999308 0.991449790402428 GO:0008376 acetylgalactosaminyltransferase activity 1/1050 34/18639 0.0294117647058824 0.522100840336134 0.860989023132978 0.991449790402428 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/1050 34/18639 0.0294117647058824 0.522100840336134 0.860989023132978 0.991449790402428 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/1050 34/18639 0.0294117647058824 0.522100840336134 0.860989023132978 0.991449790402428 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/1050 34/18639 0.0294117647058824 0.522100840336134 0.860989023132978 0.991449790402428 GO:0051427 hormone receptor binding 1/1050 34/18639 0.0294117647058824 0.522100840336134 0.860989023132978 0.991449790402428 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/1050 34/18639 0.0294117647058824 0.522100840336134 0.860989023132978 0.991449790402428 GO:0005244 voltage-gated monoatomic ion channel activity 7/1050 173/18639 0.0404624277456647 0.718265895953757 0.861673879435412 0.991449790402428 GO:0005262 calcium channel activity 5/1050 131/18639 0.0381679389312977 0.677535441657579 0.86727837975637 0.994130331273845 GO:0005154 epidermal growth factor receptor binding 1/1050 35/18639 0.0285714285714286 0.507183673469388 0.868834308040818 0.994130331273845 GO:0005343 organic acid:sodium symporter activity 1/1050 35/18639 0.0285714285714286 0.507183673469388 0.868834308040818 0.994130331273845 GO:0034061 DNA polymerase activity 1/1050 35/18639 0.0285714285714286 0.507183673469388 0.868834308040818 0.994130331273845 GO:0140566 histone reader activity 1/1050 35/18639 0.0285714285714286 0.507183673469388 0.868834308040818 0.994130331273845 GO:0050660 flavin adenine dinucleotide binding 3/1050 86/18639 0.0348837209302326 0.619235880398671 0.869744438044202 0.994130331273845 GO:0015179 L-amino acid transmembrane transporter activity 2/1050 62/18639 0.032258064516129 0.572626728110599 0.871320862390057 0.994837775849747 GO:0000993 RNA polymerase II complex binding 1/1050 36/18639 0.0277777777777778 0.493095238095238 0.876237230883064 0.995902145858249 GO:0004190 aspartic-type endopeptidase activity 1/1050 36/18639 0.0277777777777778 0.493095238095238 0.876237230883064 0.995902145858249 GO:0016409 palmitoyltransferase activity 1/1050 36/18639 0.0277777777777778 0.493095238095238 0.876237230883064 0.995902145858249 GO:0045505 dynein intermediate chain binding 1/1050 36/18639 0.0277777777777778 0.493095238095238 0.876237230883064 0.995902145858249 GO:1901682 sulfur compound transmembrane transporter activity 2/1050 63/18639 0.0317460317460317 0.563537414965986 0.877045681867466 0.995902145858249 GO:0019213 deacetylase activity 1/1050 37/18639 0.027027027027027 0.47976833976834 0.883222712126561 0.998551031446678 GO:0030280 structural constituent of skin epidermis 1/1050 37/18639 0.027027027027027 0.47976833976834 0.883222712126561 0.998551031446678 GO:0030551 cyclic nucleotide binding 1/1050 37/18639 0.027027027027027 0.47976833976834 0.883222712126561 0.998551031446678 GO:0070001 aspartic-type peptidase activity 1/1050 37/18639 0.027027027027027 0.47976833976834 0.883222712126561 0.998551031446678 GO:0120013 lipid transfer activity 2/1050 65/18639 0.0307692307692308 0.546197802197802 0.887796144506295 0.999999908415044 GO:0043531 ADP binding 1/1050 38/18639 0.0263157894736842 0.467142857142857 0.88981426960786 0.999999908415044 GO:0015291 secondary active transmembrane transporter activity 12/1050 287/18639 0.0418118466898955 0.742220009955202 0.889907449207905 0.999999908415044 GO:0101005 deubiquitinase activity 4/1050 115/18639 0.0347826086956522 0.61744099378882 0.89428417397568 0.999999908415044 GO:0008514 organic anion transmembrane transporter activity 11/1050 269/18639 0.0408921933085502 0.725894848645778 0.897300025303267 0.999999908415044 GO:0008173 RNA methyltransferase activity 2/1050 67/18639 0.0298507462686567 0.529893390191898 0.897669221477825 0.999999908415044 GO:0042054 histone methyltransferase activity 2/1050 67/18639 0.0298507462686567 0.529893390191898 0.897669221477825 0.999999908415044 GO:0050997 quaternary ammonium group binding 1/1050 40/18639 0.025 0.443785714285714 0.901903140296326 0.999999908415044 GO:0071949 FAD binding 1/1050 40/18639 0.025 0.443785714285714 0.901903140296326 0.999999908415044 GO:0140223 general transcription initiation factor activity 2/1050 68/18639 0.0294117647058824 0.522100840336134 0.902296564978918 0.999999908415044 GO:0016410 N-acyltransferase activity 3/1050 94/18639 0.0319148936170213 0.566534954407295 0.905273196851619 0.999999908415044 GO:0016279 protein-lysine N-methyltransferase activity 2/1050 69/18639 0.0289855072463768 0.514534161490683 0.9067279452577 0.999999908415044 GO:0001727 lipid kinase activity 1/1050 41/18639 0.024390243902439 0.432961672473868 0.907441163990549 0.999999908415044 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/1050 41/18639 0.024390243902439 0.432961672473868 0.907441163990549 0.999999908415044 GO:0140828 metal cation:monoatomic cation antiporter activity 1/1050 41/18639 0.024390243902439 0.432961672473868 0.907441163990549 0.999999908415044 GO:0140597 protein carrier chaperone 7/1050 188/18639 0.0372340425531915 0.660957446808511 0.910479058794435 0.999999908415044 GO:0022843 voltage-gated monoatomic cation channel activity 5/1050 143/18639 0.034965034965035 0.620679320679321 0.910775770712029 0.999999908415044 GO:0016278 lysine N-methyltransferase activity 2/1050 70/18639 0.0285714285714286 0.507183673469388 0.910970729731307 0.999999908415044 GO:0032182 ubiquitin-like protein binding 4/1050 120/18639 0.0333333333333333 0.591714285714286 0.91191252385351 0.999999908415044 GO:0008307 structural constituent of muscle 1/1050 42/18639 0.0238095238095238 0.42265306122449 0.912666821470381 0.999999908415044 GO:0031492 nucleosomal DNA binding 1/1050 42/18639 0.0238095238095238 0.42265306122449 0.912666821470381 0.999999908415044 GO:0035198 miRNA binding 1/1050 42/18639 0.0238095238095238 0.42265306122449 0.912666821470381 0.999999908415044 GO:0043175 RNA polymerase core enzyme binding 1/1050 42/18639 0.0238095238095238 0.42265306122449 0.912666821470381 0.999999908415044 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 6/1050 167/18639 0.0359281437125748 0.637775876817793 0.91420325868279 0.999999908415044 GO:0003713 transcription coactivator activity 10/1050 256/18639 0.0390625 0.693415178571429 0.91682598928583 0.999999908415044 GO:0005245 voltage-gated calcium channel activity 1/1050 43/18639 0.0232558139534884 0.412823920265781 0.917597715563843 0.999999908415044 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/1050 43/18639 0.0232558139534884 0.412823920265781 0.917597715563843 0.999999908415044 GO:0005249 voltage-gated potassium channel activity 3/1050 98/18639 0.0306122448979592 0.543411078717201 0.919527812666216 0.999999908415044 GO:0008170 N-methyltransferase activity 3/1050 98/18639 0.0306122448979592 0.543411078717201 0.919527812666216 0.999999908415044 GO:0001046 core promoter sequence-specific DNA binding 1/1050 44/18639 0.0227272727272727 0.403441558441558 0.922250458016949 0.999999908415044 GO:0030547 signaling receptor inhibitor activity 1/1050 44/18639 0.0227272727272727 0.403441558441558 0.922250458016949 0.999999908415044 GO:0043014 alpha-tubulin binding 1/1050 44/18639 0.0227272727272727 0.403441558441558 0.922250458016949 0.999999908415044 GO:0005216 monoatomic ion channel activity 19/1050 448/18639 0.0424107142857143 0.752850765306122 0.923783427247805 0.999999908415044 GO:0005267 potassium channel activity 4/1050 124/18639 0.032258064516129 0.572626728110599 0.924078775466501 0.999999908415044 GO:0003684 damaged DNA binding 2/1050 74/18639 0.027027027027027 0.47976833976834 0.926196007734681 0.999999908415044 GO:0031491 nucleosome binding 2/1050 74/18639 0.027027027027027 0.47976833976834 0.926196007734681 0.999999908415044 GO:0051539 4 iron, 4 sulfur cluster binding 1/1050 45/18639 0.0222222222222222 0.39447619047619 0.926640725243741 0.999999908415044 GO:0019842 vitamin binding 5/1050 150/18639 0.0333333333333333 0.591714285714286 0.929905606650378 0.999999908415044 GO:0000510 H3-H4 histone complex chaperone activity 5/1050 151/18639 0.033112582781457 0.587795648060549 0.932317467079604 0.999999908415044 GO:0140584 chromatin extrusion motor activity 5/1050 151/18639 0.033112582781457 0.587795648060549 0.932317467079604 0.999999908415044 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/1050 151/18639 0.033112582781457 0.587795648060549 0.932317467079604 0.999999908415044 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/1050 151/18639 0.033112582781457 0.587795648060549 0.932317467079604 0.999999908415044 GO:0015616 DNA translocase activity 5/1050 152/18639 0.0328947368421053 0.583928571428571 0.934654920865224 0.999999908415044 GO:0140674 ATP-dependent histone chaperone activity 5/1050 152/18639 0.0328947368421053 0.583928571428571 0.934654920865224 0.999999908415044 GO:0061749 forked DNA-dependent helicase activity 1/1050 47/18639 0.0212765957446809 0.377689969604863 0.934692175758349 0.999999908415044 GO:0140359 ABC-type transporter activity 1/1050 47/18639 0.0212765957446809 0.377689969604863 0.934692175758349 0.999999908415044 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/1050 47/18639 0.0212765957446809 0.377689969604863 0.934692175758349 0.999999908415044 GO:0001653 peptide receptor activity 4/1050 128/18639 0.03125 0.554732142857143 0.934712889382613 0.999999908415044 GO:0003774 cytoskeletal motor activity 5/1050 153/18639 0.0326797385620915 0.580112044817927 0.936919850668773 0.999999908415044 GO:0061775 cohesin loader activity 5/1050 153/18639 0.0326797385620915 0.580112044817927 0.936919850668773 0.999999908415044 GO:0009378 four-way junction helicase activity 1/1050 48/18639 0.0208333333333333 0.369821428571429 0.938380494145491 0.999999908415044 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/1050 48/18639 0.0208333333333333 0.369821428571429 0.938380494145491 0.999999908415044 GO:0036121 double-stranded DNA helicase activity 1/1050 48/18639 0.0208333333333333 0.369821428571429 0.938380494145491 0.999999908415044 GO:0043138 3'-5' DNA helicase activity 1/1050 48/18639 0.0208333333333333 0.369821428571429 0.938380494145491 0.999999908415044 GO:0005506 iron ion binding 5/1050 154/18639 0.0324675324675325 0.576345083487941 0.939114111962706 0.999999908415044 GO:0016887 ATP hydrolysis activity 17/1050 417/18639 0.0407673860911271 0.723679342240493 0.939186946561049 0.999999908415044 GO:0004497 monooxygenase activity 3/1050 106/18639 0.0283018867924528 0.502398921832884 0.942323033425782 0.999999908415044 GO:0005179 hormone activity 4/1050 132/18639 0.0303030303030303 0.537922077922078 0.943978556149989 0.999999908415044 GO:0140104 molecular carrier activity 9/1050 249/18639 0.036144578313253 0.641617900172117 0.945041474681418 0.999999908415044 GO:0008168 methyltransferase activity 7/1050 204/18639 0.0343137254901961 0.609117647058824 0.945471400125832 0.999999908415044 GO:0004843 cysteine-type deubiquitinase activity 3/1050 108/18639 0.0277777777777778 0.493095238095238 0.947001637037331 0.999999908415044 GO:0140658 ATP-dependent chromatin remodeler activity 5/1050 158/18639 0.0316455696202532 0.561754068716094 0.947220590724974 0.999999908415044 GO:0016830 carbon-carbon lyase activity 1/1050 51/18639 0.0196078431372549 0.348067226890756 0.94824303413505 0.999999908415044 GO:0003689 DNA clamp loader activity 5/1050 160/18639 0.03125 0.554732142857143 0.950895952176233 0.999999908415044 GO:0015079 potassium ion transmembrane transporter activity 5/1050 160/18639 0.03125 0.554732142857143 0.950895952176233 0.999999908415044 GO:0005261 monoatomic cation channel activity 13/1050 341/18639 0.0381231671554252 0.676740678676163 0.951035511475505 0.999999908415044 GO:0004222 metalloendopeptidase activity 3/1050 110/18639 0.0272727272727273 0.48412987012987 0.951325163780161 0.999999908415044 GO:0005254 chloride channel activity 2/1050 83/18639 0.0240963855421687 0.427745266781411 0.951944002210406 0.999999908415044 GO:0034212 protein N-acetyltransferase activity 1/1050 53/18639 0.0188679245283019 0.334932614555256 0.953925332069974 0.999999908415044 GO:0140098 catalytic activity, acting on RNA 15/1050 387/18639 0.0387596899224806 0.688039867109635 0.954546177574145 0.999999908415044 GO:0015081 sodium ion transmembrane transporter activity 5/1050 164/18639 0.0304878048780488 0.541202090592334 0.957557476061051 0.999999908415044 GO:0140713 histone chaperone activity 5/1050 164/18639 0.0304878048780488 0.541202090592334 0.957557476061051 0.999999908415044 GO:0015103 inorganic anion transmembrane transporter activity 5/1050 165/18639 0.0303030303030303 0.537922077922078 0.959088483443135 0.999999908415044 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/1050 56/18639 0.0178571428571429 0.316989795918367 0.961301705258417 0.999999908415044 GO:0016741 transferase activity, transferring one-carbon groups 7/1050 215/18639 0.0325581395348837 0.577953488372093 0.961873783712916 0.999999908415044 GO:0061630 ubiquitin protein ligase activity 13/1050 353/18639 0.0368271954674221 0.653735329825981 0.964299073429633 0.999999908415044 GO:0017116 single-stranded DNA helicase activity 1/1050 58/18639 0.0172413793103448 0.306059113300493 0.965551426696049 0.999999908415044 GO:0036002 pre-mRNA binding 1/1050 59/18639 0.0169491525423729 0.300871670702179 0.967498092751113 0.999999908415044 GO:0052689 carboxylic ester hydrolase activity 2/1050 92/18639 0.0217391304347826 0.385900621118012 0.968972044562245 0.999999908415044 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/1050 60/18639 0.0166666666666667 0.295857142857143 0.969334852848601 0.999999908415044 GO:0051213 dioxygenase activity 2/1050 93/18639 0.021505376344086 0.381751152073733 0.97045782306316 0.999999908415044 GO:0008528 G protein-coupled peptide receptor activity 3/1050 122/18639 0.0245901639344262 0.436510538641686 0.971072327277107 0.999999908415044 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/1050 122/18639 0.0245901639344262 0.436510538641686 0.971072327277107 0.999999908415044 GO:0022836 gated channel activity 11/1050 318/18639 0.0345911949685535 0.614043126684636 0.972732094224355 0.999999908415044 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 5/1050 181/18639 0.0276243093922652 0.490370955011839 0.977607281086347 0.999999908415044 GO:0061659 ubiquitin-like protein ligase activity 13/1050 372/18639 0.0349462365591398 0.620345622119816 0.978857277965411 0.999999908415044 GO:0016298 lipase activity 3/1050 130/18639 0.0230769230769231 0.409648351648352 0.979723256749526 0.999999908415044 GO:0008094 ATP-dependent activity, acting on DNA 6/1050 210/18639 0.0285714285714286 0.507183673469388 0.980539177514827 0.999999908415044 GO:0003777 microtubule motor activity 1/1050 68/18639 0.0147058823529412 0.261050420168067 0.98074762613932 0.999999908415044 GO:0015171 amino acid transmembrane transporter activity 2/1050 102/18639 0.0196078431372549 0.348067226890756 0.981075014668458 0.999999908415044 GO:0098960 postsynaptic neurotransmitter receptor activity 1/1050 69/18639 0.0144927536231884 0.257267080745342 0.981836150858167 0.999999908415044 GO:0046943 carboxylic acid transmembrane transporter activity 5/1050 188/18639 0.0265957446808511 0.472112462006079 0.982937260714132 0.999999908415044 GO:0005342 organic acid transmembrane transporter activity 5/1050 189/18639 0.0264550264550265 0.469614512471655 0.983593370387562 0.999999908415044 GO:0015297 antiporter activity 3/1050 135/18639 0.0222222222222222 0.39447619047619 0.983810929496108 0.999999908415044 GO:0004842 ubiquitin-protein transferase activity 16/1050 449/18639 0.0356347438752784 0.632567610563156 0.983930601820491 0.999999908415044 GO:0140097 catalytic activity, acting on DNA 11/1050 336/18639 0.0327380952380952 0.581147959183674 0.984113661595655 0.999999908415044 GO:0003678 DNA helicase activity 1/1050 74/18639 0.0135135135135135 0.23988416988417 0.986422967479002 0.999999908415044 GO:0035064 methylated histone binding 1/1050 74/18639 0.0135135135135135 0.23988416988417 0.986422967479002 0.999999908415044 GO:0140101 catalytic activity, acting on a tRNA 3/1050 139/18639 0.0215827338129496 0.383124357656732 0.986500572705509 0.999999908415044 GO:0140767 enzyme-substrate adaptor activity 3/1050 139/18639 0.0215827338129496 0.383124357656732 0.986500572705509 0.999999908415044 GO:0004620 phospholipase activity 2/1050 109/18639 0.018348623853211 0.325714285714286 0.98667149205559 0.999999908415044 GO:0051536 iron-sulfur cluster binding 1/1050 76/18639 0.0131578947368421 0.233571428571429 0.987915356810375 0.999999908415044 GO:0140034 methylation-dependent protein binding 1/1050 76/18639 0.0131578947368421 0.233571428571429 0.987915356810375 0.999999908415044 GO:0003724 RNA helicase activity 1/1050 77/18639 0.012987012987013 0.230538033395176 0.988598914174438 0.999999908415044 GO:0051540 metal cluster binding 1/1050 77/18639 0.012987012987013 0.230538033395176 0.988598914174438 0.999999908415044 GO:0140030 modification-dependent protein binding 4/1050 173/18639 0.023121387283237 0.410437654830718 0.98948220349845 0.999999908415044 GO:0008186 ATP-dependent activity, acting on RNA 1/1050 79/18639 0.0126582278481013 0.224701627486438 0.989852319791888 0.999999908415044 GO:0015108 chloride transmembrane transporter activity 2/1050 121/18639 0.0165289256198347 0.293412042502952 0.992746343147486 0.999999908415044 GO:0019787 ubiquitin-like protein transferase activity 16/1050 479/18639 0.0334029227557411 0.592949597375485 0.993052282089201 0.999999908415044 GO:0015276 ligand-gated monoatomic ion channel activity 4/1050 186/18639 0.021505376344086 0.381751152073733 0.99400766002444 0.999999908415044 GO:0022834 ligand-gated channel activity 4/1050 188/18639 0.0212765957446809 0.377689969604863 0.99451075936083 0.999999908415044 GO:0016755 aminoacyltransferase activity 16/1050 496/18639 0.032258064516129 0.572626728110599 0.99578337938364 0.999999908415044 GO:0016874 ligase activity 3/1050 167/18639 0.0179640718562874 0.318887938408897 0.996342807009704 0.999999908415044 GO:0030594 neurotransmitter receptor activity 1/1050 97/18639 0.0103092783505155 0.18300441826215 0.996444513087281 0.999999908415044 GO:0099094 ligand-gated monoatomic cation channel activity 2/1050 136/18639 0.0147058823529412 0.261050420168067 0.996647240039511 0.999999908415044 GO:0004386 helicase activity 2/1050 155/18639 0.0129032258064516 0.22905069124424 0.998756990460866 0.999999908415044 GO:0016779 nucleotidyltransferase activity 1/1050 136/18639 0.00735294117647059 0.130525210084034 0.99963483549646 0.999999908415044 GO:0042393 histone binding 3/1050 247/18639 0.0121457489878543 0.215604395604396 0.999930492916801 0.999999908415044 GO:0045182 translation regulator activity 4/1050 356/18639 0.0112359550561798 0.199454253611557 0.99999828705757 0.999999908415044 GO:0030371 translation repressor activity 2/1050 329/18639 0.0060790273556231 0.107911419887104 0.999999908415044 0.999999908415044