category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore NA NA hsa04382 Cornified envelope formation 14/66 217/9376 9.16520039100684 S100A6/S100A10/KRT18/KRT8/KRT24/KRT7/S100A11/KRT6A/S100A4/KRT19/SPRR3/KRT14/KRT17/KRT5 10.2460259291031 NA NA hsa04519 Cadherin signaling 10/66 404/9376 3.51635163516352 KRT18/KRT8/KRT24/KRT7/KRT6A/KRT19/KRT14/KRT17/ACTG1/KRT5 4.35311504505932 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 5/66 99/9376 7.17477808386899 KRT18/KRT24/KRT19/KRT14/KRT17 5.20017475405068 Genetic Information Processing Translation hsa03010 Ribosome 7/66 222/9376 4.47938847938848 RPL37A/RPL27A/RPL34/RPS28/RPL8/RPL31/RPL37 4.41729821517894 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 7/66 238/9376 4.17825311942959 RPL37A/RPL27A/RPL34/RPS28/RPL8/RPL31/RPL37 4.18151971821119 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 5/66 139/9376 5.11009374318727 KRT18/KRT24/KRT19/KRT14/KRT17 4.11032744797785 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 6/66 248/9376 3.43695014662757 S100A10/ANXA2/GAPDH/ACTG1/MYL12B/KIF5B 3.27466919943812 Genetic Information Processing Folding, sorting and degradation hsa03060 Protein export 2/66 31/9376 9.16520039100684 SRP72/SRP54 3.83390023208948 Metabolism Amino acid metabolism hsa00250 Alanine, aspartate and glutamate metabolism 2/66 37/9376 7.67895167895168 NIT2/RIMKLB 3.42721808790912 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 4/66 170/9376 3.34260249554367 IGF2/GSTP1/TXNRD1/ACTG1 2.5951970716704 Organismal Systems Immune system hsa04611 Platelet activation 3/66 126/9376 3.38239538239538 ACTG1/MYL12B/VAMP8 2.26678855027787 Environmental Information Processing Signal transduction hsa04330 Notch signaling pathway 2/66 62/9376 4.58260019550342 RBPJ/HDAC2 2.38291657811318 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 3/66 142/9376 3.00128040973111 CTSL/GSTP1/ACTG1 2.02320526593577 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 4/66 235/9376 2.4180528691167 MT-ND3/ACTG1/NDUFAF2/NDUFA10 1.85358397033373 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 3/66 149/9376 2.86028065893838 GNB2/MT-ND3/NDUFA10 1.92718812155886 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 4/66 250/9376 2.2729696969697 CTSL/OSBP/AP1B1/VAMP8 1.7176339002125 Metabolism Metabolism of other amino acids hsa00450 Selenocompound metabolism 1/66 17/9376 8.35650623885918 TXNRD1 2.55601919042046 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 3/66 169/9376 2.52178590640129 CTSL/TAX1BP1/VAMP8 1.68081766554631 Organismal Systems Digestive system hsa04980 Cobalamin transport and metabolism 1/66 18/9376 7.89225589225589 PRDX1 2.46427341006023 Human Diseases Infectious disease: viral hsa05164 Influenza A 3/66 173/9376 2.46347871781398 ACTG1/KPNA6/XPO1 1.63578988076462 Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 2/66 93/9376 3.05506679700228 ACTG1/MYL12B 1.67689553013948 Cellular Processes Cell motility hsa04814 Motor proteins 3/66 194/9376 2.19681349578257 ACTG1/MYL12B/KIF5B 1.4182130067506 Genetic Information Processing Translation hsa03015 mRNA surveillance pathway 2/66 103/9376 2.75845837010886 RNMT/HBS1L 1.51085692391249 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 4/66 308/9376 1.84494293585203 MT-ND3/NDUFA10/HDAC2/KIF5B 1.26949135392966 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 3/66 204/9376 2.08912655971479 IGF2/CTSL/ACTG1 1.3241713133325 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 3/66 205/9376 2.07893569844789 MT-ND3/GAPDH/NDUFA10 1.31506406941762 Genetic Information Processing Translation hsa03013 Nucleocytoplasmic transport 2/66 108/9376 2.6307519640853 KPNA6/XPO1 1.4351243753628 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 2/66 116/9376 2.44932079414838 ACTG1/MYL12B 1.32242420591676 Genetic Information Processing Chromosome hsa03082 ATP-dependent chromatin remodeling 2/66 117/9376 2.42838642838643 ACTG1/HDAC2 1.30899916481562 NA NA hsa04081 Hormone signaling 3/66 219/9376 1.94603569946036 IGF2/CSH1/GNB2 1.19271241807499 Genetic Information Processing Folding, sorting and degradation hsa04130 SNARE interactions in vesicular transport 1/66 33/9376 4.3048668503214 VAMP8 1.60121823720105 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 2/66 122/9376 2.32886239443617 ACTG1/HDAC2 1.24387845258788 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 3/66 232/9376 1.83699059561129 ACTG1/MYL12B/DIAPH2 1.08687406950692 Metabolism Glycan biosynthesis and metabolism hsa00512 Mucin type O-glycan biosynthesis 1/66 36/9376 3.94612794612795 C1GALT1 1.49111857900369 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 3/66 233/9376 1.82910651580179 PDLIM1/ACTG1/DIAPH2 1.07901304272444 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 3/66 238/9376 1.79067990832697 IGF2/GNB2/FOXO4 1.04027070948207 Metabolism Metabolism of cofactors and vitamins hsa00760 Nicotinate and nicotinamide metabolism 1/66 38/9376 3.7384370015949 NMRK1 1.42413245335304 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 2/66 133/9376 2.13624971519708 FBXO32/FOXO4 1.11115820319293 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 2/66 133/9376 2.13624971519708 GNB2/KIF5B 1.11115820319293 Cellular Processes Cell growth and death hsa04210 Apoptosis 2/66 137/9376 2.07387746073877 CTSL/ACTG1 1.06606894584648 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 2/66 138/9376 2.05884936319719 MT-ND3/NDUFA10 1.05503656014949 Cellular Processes Cell growth and death hsa04216 Ferroptosis 1/66 42/9376 3.38239538239538 FTH1 1.30282880196162 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 4/66 368/9376 1.54413702239789 MT-ND3/ACTG1/NDUFA10/KIF5B 0.896604185354611 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 3/66 253/9376 1.68451311534315 ACTG1/MYL12B/FOXO4 0.92930005384526 Metabolism Glycan biosynthesis and metabolism hsa00513 Various types of N-glycan biosynthesis 1/66 44/9376 3.22865013774105 MAN1A2 1.24756630119163 Organismal Systems Excretory system hsa04962 Vasopressin-regulated water reabsorption 1/66 44/9376 3.22865013774105 ARHGDIA 1.24756630119163 Metabolism Metabolism of cofactors and vitamins hsa00860 Porphyrin metabolism 1/66 46/9376 3.08827404479578 FTH1 1.1953865089454 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 4/66 388/9376 1.46454233052171 MT-ND3/GAPDH/NDUFA10/KIF5B 0.78685080013365 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 3/66 268/9376 1.59023066485753 MT-ND3/NDUFA10/KIF5B 0.825392314343144 Metabolism Glycan biosynthesis and metabolism hsa00514 Other types of O-glycan biosynthesis 1/66 49/9376 2.89919604205318 C1GALT1 1.12222415844054 Cellular Processes Transport and catabolism hsa04145 Phagosome 2/66 155/9376 1.83304007820137 CTSL/ACTG1 0.880492172959539 Human Diseases Infectious disease: bacterial hsa05110 Vibrio cholerae infection 1/66 51/9376 2.78550207961973 ACTG1 1.07647461681609 Human Diseases Neurodegenerative disease hsa05020 Prion disease 3/66 275/9376 1.5497520661157 MT-ND3/NDUFA10/KIF5B 0.779060930840237 Cellular Processes Cell growth and death hsa04110 Cell cycle 2/66 158/9376 1.79823551975451 CDC26/HDAC2 0.851969418676113 Metabolism Glycan biosynthesis and metabolism hsa00510 N-Glycan biosynthesis 1/66 56/9376 2.53679653679654 MAN1A2 0.971147498789242 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 1/66 56/9376 2.53679653679654 HBS1L 0.971147498789242 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 2/66 170/9376 1.67130124777184 ACTG1/MYL12B 0.743685296903875 Metabolism Metabolism of other amino acids hsa00480 Glutathione metabolism 1/66 59/9376 2.40780688238315 GSTP1 0.913300735882364 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 2/66 174/9376 1.63288052943225 MAN1A2/DNAJA2 0.709476491960959 Organismal Systems Digestive system hsa04978 Mineral absorption 1/66 61/9376 2.32886239443617 FTH1 0.87667024175089 Organismal Systems Aging hsa04213 Longevity regulating pathway - multiple species 1/66 62/9376 2.29130009775171 HDAC2 0.858890259123468 Genetic Information Processing Translation hsa03008 Ribosome biogenesis in eukaryotes 2/66 183/9376 1.55257492962411 GNL3/XPO1 0.635580928821367 Metabolism Carbohydrate metabolism hsa00010 Glycolysis / Gluconeogenesis 1/66 67/9376 2.12030755314337 GAPDH 0.774829086937305 Human Diseases Substance dependence hsa05031 Amphetamine addiction 1/66 69/9376 2.05884936319719 HDAC2 0.743252936381486 Human Diseases Substance dependence hsa05034 Alcoholism 2/66 191/9376 1.48754561320006 GNB2/HDAC2 0.57315900742918 Human Diseases Cancer: overview hsa05204 Chemical carcinogenesis - DNA adducts 1/66 70/9376 2.02943722943723 GSTP1 0.727863818964418 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 1/66 70/9376 2.02943722943723 ACTG1 0.727863818964418 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 2/66 195/9376 1.45703185703186 ACTG1/HDAC2 0.543002151956137 Metabolism Xenobiotics biodegradation and metabolism hsa00982 Drug metabolism - cytochrome P450 1/66 73/9376 1.94603569946036 GSTP1 0.68318796972284 Genetic Information Processing Information processing in viruses hsa03250 Viral life cycle - HIV-1 1/66 73/9376 1.94603569946036 XPO1 0.68318796972284 Human Diseases Cancer: specific types hsa05223 Non-small cell lung cancer 1/66 73/9376 1.94603569946036 KIF5B 0.68318796972284 Metabolism Global and overview maps hsa01230 Biosynthesis of amino acids 1/66 75/9376 1.89414141414141 GAPDH 0.654568023510287 Human Diseases Drug resistance: antineoplastic hsa01524 Platinum drug resistance 1/66 75/9376 1.89414141414141 GSTP1 0.654568023510287 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 1/66 75/9376 1.89414141414141 PERP 0.654568023510287 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 2/66 200/9376 1.42060606060606 GAPDH/ACTG1 0.506228494622631 Organismal Systems Digestive system hsa04971 Gastric acid secretion 1/66 76/9376 1.86921850079745 ACTG1 0.640585418640966 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 2/66 203/9376 1.3996118823705 ACTG1/MYL12B 0.484633555677332 Human Diseases Cancer: specific types hsa05220 Chronic myeloid leukemia 1/66 77/9376 1.84494293585203 HDAC2 0.626812117442052 Genetic Information Processing Folding, sorting and degradation hsa03018 RNA degradation 1/66 78/9376 1.82128982128982 CNOT7 0.613241781054214 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 1/66 78/9376 1.82128982128982 ACTG1 0.613241781054214 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 2/66 205/9376 1.3859571322986 RBPJ/HDAC2 0.470425028805235 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 2/66 205/9376 1.3859571322986 RBPJ/HDAC2 0.470425028805235 Metabolism Xenobiotics biodegradation and metabolism hsa00980 Metabolism of xenobiotics by cytochrome P450 1/66 79/9376 1.79823551975451 GSTP1 0.599868344763565 Metabolism Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes 1/66 82/9376 1.73244641537324 GSTP1 0.560872588776533 Organismal Systems Immune system hsa04612 Antigen processing and presentation 1/66 82/9376 1.73244641537324 CTSL 0.560872588776533 Genetic Information Processing Chromosome hsa03083 Polycomb repressive complex 1/66 83/9376 1.71157356699525 HDAC2 0.548231076570602 Cellular Processes Transport and catabolism hsa04146 Peroxisome 1/66 83/9376 1.71157356699525 PRDX1 0.548231076570602 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 2/66 214/9376 1.32766921551968 GNB2/AP1B1 0.408253719166846 Human Diseases Cardiovascular disease hsa05412 Arrhythmogenic right ventricular cardiomyopathy 1/66 86/9376 1.65186751233263 ACTG1 0.511309040256771 Organismal Systems Nervous system hsa04727 GABAergic synapse 1/66 89/9376 1.59618658495063 GNB2 0.475797598393923 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 2/66 224/9376 1.26839826839827 CDC26/XPO1 0.342317008756404 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 3/66 362/9376 1.17729784028127 IGF2/CSH1/GNB2 0.289655459923012 Human Diseases Substance dependence hsa05032 Morphine addiction 1/66 91/9376 1.56110556110556 GNB2 0.452852824265025 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 2/66 227/9376 1.25163529568816 MT-ND3/NDUFA10 0.323132349029046 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 1/66 93/9376 1.52753339850114 RBPJ 0.43045724802534 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 1/66 94/9376 1.51128304319794 MAPK6 0.419456858348605 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 1/66 95/9376 1.49537480063796 CTSL 0.408583752131508 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 1/66 97/9376 1.46454233052171 GNB2 0.387207124523115 Human Diseases Cardiovascular disease hsa05410 Hypertrophic cardiomyopathy 1/66 99/9376 1.4349556167738 ACTG1 0.366303887647153 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 1/66 103/9376 1.37922918505443 PRDX1 0.325831449711092 Cellular Processes Transport and catabolism hsa04137 Mitophagy - animal 1/66 105/9376 1.35295815295815 TAX1BP1 0.306222672620386 Human Diseases Cardiovascular disease hsa05414 Dilated cardiomyopathy 1/66 105/9376 1.35295815295815 ACTG1 0.306222672620386 Cellular Processes Transport and catabolism hsa04144 Endocytosis 2/66 250/9376 1.13648484848485 EHD1/KIF5B 0.18416070954478 Human Diseases Cancer: specific types hsa05215 Prostate cancer 1/66 106/9376 1.34019439679817 GSTP1 0.296567111516881 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 1/66 110/9376 1.29146005509642 GAPDH 0.258888049086495 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 1/66 110/9376 1.29146005509642 HDAC2 0.258888049086495 Organismal Systems Endocrine system hsa04914 Progesterone-mediated oocyte maturation 1/66 110/9376 1.29146005509642 CDC26 0.258888049086495 Organismal Systems Nervous system hsa04725 Cholinergic synapse 1/66 115/9376 1.23530961791831 GNB2 0.213767866207927 Organismal Systems Nervous system hsa04726 Serotonergic synapse 1/66 115/9376 1.23530961791831 GNB2 0.213767866207927 Metabolism Global and overview maps hsa01200 Carbon metabolism 1/66 116/9376 1.22466039707419 GAPDH 0.204990053548741 Organismal Systems Nervous system hsa04724 Glutamatergic synapse 1/66 116/9376 1.22466039707419 GNB2 0.204990053548741 Organismal Systems Nervous system hsa04722 Neurotrophin signaling pathway 1/66 120/9376 1.18383838383838 ARHGDIA 0.170646705774983 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 1/66 122/9376 1.16443119721808 CSH1 0.153915427217417 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 1/66 130/9376 1.09277389277389 GNB2 0.0896815853619217 Cellular Processes Cell growth and death hsa04114 Oocyte meiosis 1/66 138/9376 1.02942468159859 CDC26 0.0293187264744984 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 1/66 138/9376 1.02942468159859 ACTG1 0.0293187264744984 NA NA hsa04517 IgSF CAM signaling 2/66 299/9376 0.950238167629472 ACTG1/MYL12B -0.0736280936164423 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/66 140/9376 1.01471861471861 GNB2 0.0147731041072846 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 1/66 142/9376 1.0004268032437 CDC26 0.000431479050103631 Human Diseases Neurodegenerative disease hsa05017 Spinocerebellar ataxia 1/66 144/9376 0.986531986531987 RBPJ -0.0137125951981139 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 3/66 480/9376 0.887878787878788 MT-ND3/NDUFA10/KIF5B -0.212321405899515 NA NA hsa04518 Integrin signaling 1/66 154/9376 0.922471467926013 ACTG1 -0.0816755613569222 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 1/66 154/9376 0.922471467926013 ACTG1 -0.0816755613569222 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 1/66 157/9376 0.904844624589847 ACTG1 -0.101233443819278 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 1/66 157/9376 0.904844624589847 NDUFA10 -0.101233443819278 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 2/66 333/9376 0.853216853216853 RBPJ/HDAC2 -0.229627982857785 Cellular Processes Cell growth and death hsa04217 Necroptosis 1/66 168/9376 0.845598845598845 FTH1 -0.170022067942485 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 1/66 168/9376 0.845598845598845 CSH1 -0.170022067942485 Organismal Systems Development and regeneration hsa04360 Axon guidance 1/66 184/9376 0.772068511198946 MYL12B -0.262900248357964 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/66 193/9376 0.736065316376197 GNB2 -0.311936067190817 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 1/66 196/9376 0.724799010513296 GNB2 -0.327823023633852 NA NA hsa04082 Neuroactive ligand signaling 1/66 199/9376 0.713872392264352 GNB2 -0.343493641115386 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 1/66 201/9376 0.706769184381125 HDAC2 -0.353824063693368 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 1/66 212/9376 0.670097198399085 ACTG1 -0.409066730224598 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 1/66 217/9376 0.654657170786203 KPNA6 -0.433350244098305 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 1/66 227/9376 0.62581764784408 GNB2 -0.480498660121175 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 1/66 298/9376 0.476713443156396 CSH1 -0.772921496797048 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 1/66 300/9376 0.473535353535354 IGF2 -0.780306746235064 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 1/66 323/9376 0.439816117834694 HDAC2 -0.86261772039855 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 1/66 370/9376 0.383947583947584 CSH1 -1.01797080161597