ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 57/2108 175/18639 0.325714285714286 2.87997560314448 4.33423313070983e-14 5.13173202676044e-11 GO:0003712 transcription coregulator activity 106/2108 495/18639 0.214141414141414 1.89344488528549 4.49996925144367e-11 2.66398179685465e-08 GO:0045296 cadherin binding 76/2108 334/18639 0.227544910179641 2.01195900419275 1.53913902289701e-09 6.07446867703354e-07 GO:0061650 ubiquitin-like protein conjugating enzyme activity 20/2108 41/18639 0.48780487804878 4.31318554172259 2.7326346521662e-09 8.08859857041195e-07 GO:0031625 ubiquitin protein ligase binding 66/2108 302/18639 0.218543046357616 1.93236425097704 9.32641154277006e-08 2.20849425332795e-05 GO:0044389 ubiquitin-like protein ligase binding 68/2108 322/18639 0.211180124223602 1.86726106992587 2.36258924769135e-07 4.66217611544427e-05 GO:0061631 ubiquitin conjugating enzyme activity 16/2108 35/18639 0.457142857142857 4.04207102195717 3.33470583425688e-07 5.64041672537163e-05 GO:0019787 ubiquitin-like protein transferase activity 91/2108 479/18639 0.189979123173278 1.67980117496524 4.09820614110879e-07 5.64652954179648e-05 GO:0004674 protein serine/threonine kinase activity 84/2108 433/18639 0.193995381062356 1.71531304915619 4.62822139317587e-07 5.64652954179648e-05 GO:0051020 GTPase binding 66/2108 315/18639 0.20952380952381 1.8526158850637 4.76902832922e-07 5.64652954179648e-05 GO:0106310 protein serine kinase activity 72/2108 361/18639 0.199445983379501 1.76350744032757 1.04678044877211e-06 0.00010377391243814 GO:0016755 aminoacyltransferase activity 92/2108 496/18639 0.185483870967742 1.64005401848565 1.05176262606223e-06 0.00010377391243814 GO:0019003 GDP binding 24/2108 75/18639 0.32 2.82944971537002 1.3696464683857e-06 0.000124743186043744 GO:0003714 transcription corepressor activity 46/2108 204/18639 0.225490196078431 1.99379115972765 3.25775280576665e-06 0.000275512808716265 GO:0004842 ubiquitin-protein transferase activity 83/2108 449/18639 0.184855233853007 1.6344955900314 4.01568665580924e-06 0.000305295758079424 GO:0003713 transcription coactivator activity 54/2108 256/18639 0.2109375 1.86511577917457 4.12561835242465e-06 0.000305295758079424 GO:0019902 phosphatase binding 43/2108 190/18639 0.226315789473684 2.00109108159393 6.0879526883535e-06 0.00042400799900062 GO:0035403 histone H3T6 kinase activity 51/2108 247/18639 0.206477732793522 1.82568238213399 1.40631308410951e-05 0.000925041495325368 GO:0031267 small GTPase binding 56/2108 283/18639 0.197879858657244 1.74965971798499 2.01869545154915e-05 0.00125796600770221 GO:0019903 protein phosphatase binding 34/2108 144/18639 0.236111111111111 2.08770161290323 2.17126522665631e-05 0.00128538901418054 GO:0140857 histone H3T45 kinase activity 50/2108 246/18639 0.203252032520325 1.79716064238441 2.63900846840018e-05 0.00138404635649729 GO:0035402 histone H3T11 kinase activity 50/2108 247/18639 0.202429149797571 1.78988468836666 2.95187531720495e-05 0.00138404635649729 GO:0140996 histone H3 kinase activity 66/2108 357/18639 0.184873949579832 1.63466107505621 3.76357588963583e-05 0.00138404635649729 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 49/2108 243/18639 0.201646090534979 1.78296085459273 3.91717038607039e-05 0.00138404635649729 GO:0004676 3-phosphoinositide-dependent protein kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0004711 ribosomal protein S6 kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0035175 histone H3S10 kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0035979 histone H2AXS139 kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0044022 histone H3S28 kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0044023 histone H4S1 kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0044024 histone H2AS1 kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0044025 histone H2BS14 kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0072354 histone H3T3 kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0072371 histone H2AS121 kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0072518 Rho-dependent protein serine/threonine kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0140823 histone H2BS36 kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0140855 histone H3S57 kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0140995 histone H2A kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0140997 histone H4 kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0140998 histone H2B kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:1990244 histone H2AT120 kinase activity 49/2108 245/18639 0.2 1.76840607210626 4.87714662482417e-05 0.00138404635649729 GO:0035173 histone kinase activity 66/2108 360/18639 0.183333333333333 1.62103889943074 4.909623899737e-05 0.00138404635649729 GO:0004677 DNA-dependent protein kinase activity 49/2108 246/18639 0.199186991869919 1.76121742953672 5.43384088708193e-05 0.00149620176983837 GO:0098641 cadherin binding involved in cell-cell adhesion 9/2108 18/18639 0.5 4.42101518026565 5.56363518271584e-05 0.00149712364916717 GO:0004679 AMP-activated protein kinase activity 49/2108 248/18639 0.19758064516129 1.74701406316949 6.72509408148086e-05 0.00176944697610519 GO:0001098 basal transcription machinery binding 18/2108 60/18639 0.3 2.65260910815939 7.31994515016771e-05 0.00183986628011663 GO:0001099 basal RNA polymerase II transcription machinery binding 18/2108 60/18639 0.3 2.65260910815939 7.31994515016771e-05 0.00183986628011663 GO:0031490 chromatin DNA binding 30/2108 128/18639 0.234375 2.07235086574953 7.45891735182418e-05 0.00183986628011663 GO:0019208 phosphatase regulator activity 28/2108 117/18639 0.239316239316239 2.11604145380236 8.67249217373808e-05 0.00209555729259304 GO:0000993 RNA polymerase II complex binding 13/2108 36/18639 0.361111111111111 3.19295540796964 8.91791240260307e-05 0.00211176165693641 GO:0141003 histone H2AX kinase activity 64/2108 354/18639 0.180790960451977 1.598559161226 9.68121286229686e-05 0.00224756000567833 GO:0019888 protein phosphatase regulator activity 26/2108 107/18639 0.242990654205607 2.14853074181135 0.000116909165109826 0.00266193175942372 GO:0031492 nucleosomal DNA binding 14/2108 42/18639 0.333333333333333 2.94734345351044 0.000130929467863822 0.00292491490473143 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 19/2108 68/18639 0.279411764705882 2.47056730661904 0.000134825028399332 0.0029561635856446 GO:0031491 nucleosome binding 20/2108 74/18639 0.27027027027027 2.38973793527873 0.000149975323675078 0.00322855969511441 GO:0140030 modification-dependent protein binding 36/2108 173/18639 0.208092485549133 1.83996007502386 0.000206952635545904 0.00437557000868482 GO:0019207 kinase regulator activity 53/2108 287/18639 0.184668989547038 1.63284881222355 0.000215491759806015 0.00447617971246178 GO:0051010 microtubule plus-end binding 9/2108 21/18639 0.428571428571429 3.78944158308485 0.000245032179918697 0.0050020362245472 GO:0098632 cell-cell adhesion mediator activity 16/2108 55/18639 0.290909090909091 2.57222701397274 0.000269362903963117 0.00540551997105645 GO:0015631 tubulin binding 66/2108 385/18639 0.171428571428571 1.51577663323394 0.000366295807487474 0.00722823726775283 GO:0043175 RNA polymerase core enzyme binding 13/2108 42/18639 0.30952380952381 2.73681892111683 0.000514111016125151 0.00997881054249474 GO:0051219 phosphoprotein binding 22/2108 93/18639 0.236559139784946 2.09166309603966 0.000564321476747662 0.0107767198140199 GO:0005520 insulin-like growth factor binding 8/2108 19/18639 0.421052631578947 3.72296015180266 0.000631404585053207 0.0116792982577869 GO:0045309 protein phosphorylated amino acid binding 16/2108 59/18639 0.271186440677966 2.397838741839 0.000641177691517017 0.0116792982577869 GO:0070063 RNA polymerase binding 16/2108 59/18639 0.271186440677966 2.397838741839 0.000641177691517017 0.0116792982577869 GO:0061659 ubiquitin-like protein ligase activity 63/2108 372/18639 0.169354838709677 1.49744062557385 0.000681048609910512 0.0120510955492706 GO:0071889 14-3-3 protein binding 11/2108 33/18639 0.333333333333333 2.94734345351044 0.000681945440710412 0.0120510955492706 GO:0001222 transcription corepressor binding 14/2108 49/18639 0.285714285714286 2.52629438872323 0.000781476606376665 0.0136068867933819 GO:0042393 histone binding 45/2108 247/18639 0.182186234817814 1.61089621953 0.000832543077086683 0.0142859565691396 GO:0008017 microtubule binding 49/2108 276/18639 0.177536231884058 1.56978075241317 0.000910334805879643 0.0153976630023071 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 6/2108 12/18639 0.5 4.42101518026565 0.001047579565853 0.0172083433872936 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 7/2108 16/18639 0.4375 3.86838828273245 0.00106098738789901 0.0172083433872936 GO:0034450 ubiquitin-ubiquitin ligase activity 7/2108 16/18639 0.4375 3.86838828273245 0.00106098738789901 0.0172083433872936 GO:0004721 phosphoprotein phosphatase activity 34/2108 175/18639 0.194285714285714 1.7178801843318 0.00111082040397435 0.0177731264635896 GO:0003743 translation initiation factor activity 14/2108 51/18639 0.274509803921569 2.42722402053801 0.00120471308716119 0.0190184039359847 GO:0043021 ribonucleoprotein complex binding 34/2108 177/18639 0.192090395480226 1.69846910880262 0.00136085809714494 0.0209718255106197 GO:0061630 ubiquitin protein ligase activity 59/2108 353/18639 0.1671388101983 1.47784643419645 0.00136699236561013 0.0209718255106197 GO:0009931 calcium-dependent protein serine/threonine kinase activity 8/2108 21/18639 0.380952380952381 3.36839251829764 0.00138158985627393 0.0209718255106197 GO:0008137 NADH dehydrogenase (ubiquinone) activity 12/2108 41/18639 0.292682926829268 2.58791132503355 0.0014478896968584 0.0214287675135044 GO:0140318 protein transporter activity 12/2108 41/18639 0.292682926829268 2.58791132503355 0.0014478896968584 0.0214287675135044 GO:0003779 actin binding 71/2108 443/18639 0.160270880361174 1.41711999006258 0.00153012716897969 0.0222505116121742 GO:0043548 phosphatidylinositol 3-kinase binding 9/2108 26/18639 0.346153846153846 3.06070281710699 0.00154099827043774 0.0222505116121742 GO:0019887 protein kinase regulator activity 45/2108 255/18639 0.176470588235294 1.56035829891729 0.00162827736284058 0.0231150541646691 GO:0030695 GTPase regulator activity 77/2108 489/18639 0.157464212678937 1.39230334920432 0.00163991938330423 0.0231150541646691 GO:0017022 myosin binding 18/2108 76/18639 0.236842105263158 2.09416508538899 0.00170277091086929 0.0237185971584616 GO:0060589 nucleoside-triphosphatase regulator activity 77/2108 490/18639 0.157142857142857 1.38946191379778 0.0017354344528005 0.023892492931579 GO:0031994 insulin-like growth factor I binding 6/2108 13/18639 0.461538461538462 4.08093708947599 0.00175997614962891 0.0239518593236854 GO:0019783 ubiquitin-like protein peptidase activity 26/2108 127/18639 0.204724409448819 1.8101794438883 0.00189004548674317 0.0254297029125444 GO:0140035 ubiquitin-like protein reader activity 8/2108 22/18639 0.363636363636364 3.21528376746593 0.0019577959762511 0.0260452857964191 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 13/2108 48/18639 0.270833333333333 2.39471655597723 0.00203616216475752 0.0267868444785878 GO:0022884 macromolecule transmembrane transporter activity 10/2108 32/18639 0.3125 2.76313448766603 0.00206760666955519 0.0269016076566301 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 26/2108 128/18639 0.203125 1.79603741698292 0.00212200864385381 0.0273093286339447 GO:0140297 DNA-binding transcription factor binding 76/2108 488/18639 0.155737704918033 1.37703751516471 0.00236047252203195 0.0300516071622133 GO:1990381 ubiquitin-specific protease binding 7/2108 18/18639 0.388888888888889 3.43856736242884 0.00240694023449838 0.0303172046558094 GO:0140789 histone phosphatase activity 27/2108 136/18639 0.198529411764706 1.75540308628195 0.00248727542632282 0.0309993063659602 GO:0003954 NADH dehydrogenase activity 12/2108 44/18639 0.272727272727273 2.41146282559945 0.00280576909079172 0.0343404509103182 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 5/2108 10/18639 0.5 4.42101518026565 0.00284236840304999 0.0343404509103182 GO:0050815 phosphoserine residue binding 5/2108 10/18639 0.5 4.42101518026565 0.00284236840304999 0.0343404509103182 GO:0022853 active monoatomic ion transmembrane transporter activity 24/2108 118/18639 0.203389830508475 1.79837905637925 0.00302348251300842 0.0361596292464845 GO:0004715 non-membrane spanning protein tyrosine kinase activity 12/2108 45/18639 0.266666666666667 2.35787476280835 0.00343911646708988 0.0407191389703441 GO:0005085 guanyl-nucleotide exchange factor activity 40/2108 230/18639 0.173913043478261 1.53774441052718 0.00371961139106555 0.0436041572972437 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 6/2108 15/18639 0.4 3.53681214421252 0.00420423498621074 0.0474077545111763 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 6/2108 15/18639 0.4 3.53681214421252 0.00420423498621074 0.0474077545111763 GO:0031386 protein tag activity 6/2108 15/18639 0.4 3.53681214421252 0.00420423498621074 0.0474077545111763 GO:0141047 molecular tag activity 6/2108 15/18639 0.4 3.53681214421252 0.00420423498621074 0.0474077545111763 GO:0098631 cell adhesion mediator activity 17/2108 76/18639 0.223684210526316 1.97782258064516 0.00426762910074102 0.0474916301648537 GO:0140566 histone reader activity 10/2108 35/18639 0.285714285714286 2.52629438872323 0.00429189563145215 0.0474916301648537 GO:0031624 ubiquitin conjugating enzyme binding 9/2108 30/18639 0.3 2.65260910815939 0.00465007138928659 0.0508945622291443 GO:0002162 dystroglycan binding 5/2108 11/18639 0.454545454545455 4.01910470933241 0.00472837993682929 0.0508945622291443 GO:0042608 T cell receptor binding 5/2108 11/18639 0.454545454545455 4.01910470933241 0.00472837993682929 0.0508945622291443 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 8/2108 25/18639 0.32 2.82944971537002 0.00486145301842111 0.0518554988631585 GO:0009055 electron transfer activity 23/2108 116/18639 0.198275862068966 1.75316119217431 0.00506559733981308 0.0535506004494526 GO:0019843 rRNA binding 15/2108 65/18639 0.230769230769231 2.04046854473799 0.005181529107949 0.0542914200337311 GO:0031593 polyubiquitin modification-dependent protein binding 14/2108 59/18639 0.23728813559322 2.09810889910912 0.00523114132345536 0.054330450236589 GO:0044390 ubiquitin-like protein conjugating enzyme binding 10/2108 36/18639 0.277777777777778 2.45611954459203 0.00535110292552736 0.0550930944680382 GO:0005521 lamin binding 6/2108 16/18639 0.375 3.31576138519924 0.00609018354519776 0.0621618734268461 GO:0140463 chromatin-protein adaptor activity 13/2108 54/18639 0.240740740740741 2.12863693864643 0.00615055997161026 0.06224156415715 GO:0000287 magnesium ion binding 39/2108 230/18639 0.169565217391304 1.499300800264 0.00638751494632848 0.0640916753936688 GO:0072542 protein phosphatase activator activity 7/2108 21/18639 0.333333333333333 2.94734345351044 0.00648763723453892 0.0643971846516908 GO:0004857 enzyme inhibitor activity 64/2108 416/18639 0.153846153846154 1.36031236315866 0.00652674168767137 0.0643971846516908 GO:0005200 structural constituent of cytoskeleton 22/2108 112/18639 0.196428571428571 1.73682739224722 0.00675651475495941 0.0661133344617516 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 10/2108 38/18639 0.263157894736842 2.32685009487666 0.0080731188663444 0.0782481966384588 GO:0008320 protein transmembrane transporter activity 8/2108 27/18639 0.296296296296296 2.61986084756483 0.00812882448186692 0.0782481966384588 GO:0031489 myosin V binding 6/2108 17/18639 0.352941176470588 3.12071659783458 0.00852375346259412 0.0808273871079901 GO:0050321 tau-protein kinase activity 7/2108 22/18639 0.318181818181818 2.81337329653269 0.00860156315507327 0.0808273871079901 GO:0070034 telomerase RNA binding 7/2108 22/18639 0.318181818181818 2.81337329653269 0.00860156315507327 0.0808273871079901 GO:0003924 GTPase activity 52/2108 331/18639 0.157099697885196 1.3890802983312 0.00891423213456531 0.083105912183664 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 18/2108 89/18639 0.202247191011236 1.78827580325352 0.00997779860191342 0.0915791747648488 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 18/2108 89/18639 0.202247191011236 1.78827580325352 0.00997779860191342 0.0915791747648488 GO:0036408 histone H3K14 acetyltransferase activity 8/2108 28/18639 0.285714285714286 2.52629438872323 0.0102746025544407 0.0928635833928076 GO:0046966 nuclear thyroid hormone receptor binding 8/2108 28/18639 0.285714285714286 2.52629438872323 0.0102746025544407 0.0928635833928076 GO:0097110 scaffold protein binding 15/2108 70/18639 0.214285714285714 1.89472079154242 0.0105247868433939 0.0944041486558966 GO:0046975 histone H3K36 methyltransferase activity 5/2108 13/18639 0.384615384615385 3.40078090789666 0.0108559898772841 0.0959215821992866 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 5/2108 13/18639 0.384615384615385 3.40078090789666 0.0108559898772841 0.0959215821992866 GO:0070577 lysine-acetylated histone binding 7/2108 23/18639 0.304347826086957 2.69105271842257 0.011180184882117 0.0974149073926065 GO:0140793 histone H2AXY142 phosphatase activity 18/2108 90/18639 0.2 1.76840607210626 0.0111895501734751 0.0974149073926065 GO:0051015 actin filament binding 35/2108 209/18639 0.167464114832536 1.48072278764878 0.0113300130799617 0.0979177772749976 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 13/2108 58/18639 0.224137931034483 1.98183439115357 0.0114371762808309 0.097951982362458 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 6/2108 18/18639 0.333333333333333 2.94734345351044 0.011582160076642 0.097951982362458 GO:0070064 proline-rich region binding 6/2108 18/18639 0.333333333333333 2.94734345351044 0.011582160076642 0.097951982362458 GO:0004532 RNA exonuclease activity 10/2108 40/18639 0.25 2.21050759013283 0.0117506426022879 0.0986720627029001 GO:0010484 histone H3 acetyltransferase activity 8/2108 29/18639 0.275862068965517 2.43918078911208 0.0128128105501611 0.106833575291485 GO:0004725 protein tyrosine phosphatase activity 19/2108 98/18639 0.193877551020408 1.71427119234791 0.0129393148137148 0.1071339072688 GO:0001786 phosphatidylserine binding 13/2108 59/18639 0.220338983050847 1.94824397774419 0.0131910557253066 0.108459791519188 GO:0000175 3'-5'-RNA exonuclease activity 9/2108 35/18639 0.257142857142857 2.27366494985091 0.01367993398256 0.110938642707884 GO:0010485 histone H4 acetyltransferase activity 9/2108 35/18639 0.257142857142857 2.27366494985091 0.01367993398256 0.110938642707884 GO:0043495 protein-membrane adaptor activity 11/2108 47/18639 0.234042553191489 2.06941136097541 0.0139576796773158 0.111292216308838 GO:0004812 aminoacyl-tRNA ligase activity 10/2108 41/18639 0.24390243902439 2.1565927708613 0.0140055238429197 0.111292216308838 GO:0016875 ligase activity, forming carbon-oxygen bonds 10/2108 41/18639 0.24390243902439 2.1565927708613 0.0140055238429197 0.111292216308838 GO:0035035 histone acetyltransferase binding 7/2108 24/18639 0.291666666666667 2.57892552182163 0.0142751713893245 0.111932469701723 GO:0140033 acetylation-dependent protein binding 7/2108 24/18639 0.291666666666667 2.57892552182163 0.0142751713893245 0.111932469701723 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 13/2108 60/18639 0.216666666666667 1.91577324478178 0.0151444824892586 0.117481845029114 GO:0044548 S100 protein binding 5/2108 14/18639 0.357142857142857 3.15786798590404 0.0153387748380334 0.117481845029114 GO:0140036 ubiquitin-modified protein reader activity 6/2108 19/18639 0.315789473684211 2.79222011385199 0.0153388480981653 0.117481845029114 GO:0043539 protein serine/threonine kinase activator activity 15/2108 73/18639 0.205479452054795 1.81685555353383 0.0153798023475614 0.117481845029114 GO:0016791 phosphatase activity 43/2108 273/18639 0.157509157509158 1.39270075275768 0.0155356275820079 0.117514452413494 GO:0043995 histone H4K5 acetyltransferase activity 8/2108 30/18639 0.266666666666667 2.35787476280835 0.0157810793359337 0.117514452413494 GO:0043996 histone H4K8 acetyltransferase activity 8/2108 30/18639 0.266666666666667 2.35787476280835 0.0157810793359337 0.117514452413494 GO:0043997 histone H4K12 acetyltransferase activity 8/2108 30/18639 0.266666666666667 2.35787476280835 0.0157810793359337 0.117514452413494 GO:0048487 beta-tubulin binding 10/2108 42/18639 0.238095238095238 2.10524532393603 0.0165686811032558 0.122608240164093 GO:0002020 protease binding 24/2108 136/18639 0.176470588235294 1.56035829891729 0.0178740640815207 0.130284032211087 GO:0004709 MAP kinase kinase kinase activity 7/2108 25/18639 0.28 2.47576850094877 0.0179360618668979 0.130284032211087 GO:0019211 phosphatase activator activity 7/2108 25/18639 0.28 2.47576850094877 0.0179360618668979 0.130284032211087 GO:0048156 tau protein binding 10/2108 43/18639 0.232558139534884 2.05628613035612 0.01946285974857 0.138544160958384 GO:0005522 profilin binding 4/2108 10/18639 0.4 3.53681214421252 0.0195412794595017 0.138544160958384 GO:0008641 ubiquitin-like modifier activating enzyme activity 4/2108 10/18639 0.4 3.53681214421252 0.0195412794595017 0.138544160958384 GO:1905394 retromer complex binding 4/2108 10/18639 0.4 3.53681214421252 0.0195412794595017 0.138544160958384 GO:0004129 cytochrome-c oxidase activity 5/2108 15/18639 0.333333333333333 2.94734345351044 0.0209060447639447 0.147337839288753 GO:0005525 GTP binding 56/2108 378/18639 0.148148148148148 1.30993042378242 0.0210679192316362 0.147600096865427 GO:0016874 ligase activity 28/2108 167/18639 0.167664670658683 1.48249610835255 0.0213923614568379 0.148991505675859 GO:0008135 translation factor activity, RNA binding 16/2108 83/18639 0.192771084337349 1.70448778034338 0.0224743233432219 0.154533715657435 GO:0001046 core promoter sequence-specific DNA binding 10/2108 44/18639 0.227272727272727 2.00955235466621 0.0227101913212785 0.154533715657435 GO:0016248 channel inhibitor activity 10/2108 44/18639 0.227272727272727 2.00955235466621 0.0227101913212785 0.154533715657435 GO:0019205 nucleobase-containing compound kinase activity 10/2108 44/18639 0.227272727272727 2.00955235466621 0.0227101913212785 0.154533715657435 GO:0019210 kinase inhibitor activity 17/2108 90/18639 0.188888888888889 1.67016129032258 0.022948882212743 0.155240407946748 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 52/2108 349/18639 0.148997134670487 1.31743718838862 0.0231087849075516 0.155240407946748 GO:0042162 telomeric DNA binding 9/2108 38/18639 0.236842105263158 2.09416508538899 0.0232073920663635 0.155240407946748 GO:0004860 protein kinase inhibitor activity 16/2108 84/18639 0.19047619047619 1.68419625914882 0.024943505746729 0.164989445833112 GO:0180051 translation factor activity 16/2108 84/18639 0.19047619047619 1.68419625914882 0.024943505746729 0.164989445833112 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 6/2108 21/18639 0.285714285714286 2.52629438872323 0.0252112684374447 0.165834121277414 GO:0141110 transporter inhibitor activity 10/2108 45/18639 0.222222222222222 1.96489563567362 0.0263319545817843 0.172248807872003 GO:1901981 phosphatidylinositol phosphate binding 30/2108 185/18639 0.162162162162162 1.43384276116724 0.0269502992424576 0.17532502364324 GO:0016776 phosphotransferase activity, phosphate group as acceptor 9/2108 39/18639 0.230769230769231 2.04046854473799 0.0272353331934004 0.175948301769598 GO:0000062 fatty-acyl-CoA binding 5/2108 16/18639 0.3125 2.76313448766603 0.0276405271361024 0.175948301769598 GO:0008142 oxysterol binding 5/2108 16/18639 0.3125 2.76313448766603 0.0276405271361024 0.175948301769598 GO:0016675 oxidoreductase activity, acting on a heme group of donors 5/2108 16/18639 0.3125 2.76313448766603 0.0276405271361024 0.175948301769598 GO:0070990 snRNP binding 4/2108 11/18639 0.363636363636364 3.21528376746593 0.0280057934724574 0.177320104125078 GO:0030291 protein serine/threonine kinase inhibitor activity 10/2108 46/18639 0.217391304347826 1.92218051315898 0.0303483447308448 0.183373650124668 GO:0008234 cysteine-type peptidase activity 30/2108 187/18639 0.160427807486631 1.41850754447026 0.0306914195044835 0.183373650124668 GO:0043130 ubiquitin binding 18/2108 100/18639 0.18 1.59156546489564 0.0307379547700927 0.183373650124668 GO:0042578 phosphoric ester hydrolase activity 53/2108 363/18639 0.146005509641873 1.29098514905829 0.0309359690801922 0.183373650124668 GO:0032931 histone H3K56 acetyltransferase activity 6/2108 22/18639 0.272727272727273 2.41146282559945 0.0314399079183341 0.183373650124668 GO:0043992 histone H3K9 acetyltransferase activity 6/2108 22/18639 0.272727272727273 2.41146282559945 0.0314399079183341 0.183373650124668 GO:0043993 histone H3K18 acetyltransferase activity 6/2108 22/18639 0.272727272727273 2.41146282559945 0.0314399079183341 0.183373650124668 GO:0043994 histone H3K23 acetyltransferase activity 6/2108 22/18639 0.272727272727273 2.41146282559945 0.0314399079183341 0.183373650124668 GO:0043999 histone H2AK5 acetyltransferase activity 6/2108 22/18639 0.272727272727273 2.41146282559945 0.0314399079183341 0.183373650124668 GO:0044012 histone H2AK9 acetyltransferase activity 6/2108 22/18639 0.272727272727273 2.41146282559945 0.0314399079183341 0.183373650124668 GO:0044014 histone H2BK5 acetyltransferase activity 6/2108 22/18639 0.272727272727273 2.41146282559945 0.0314399079183341 0.183373650124668 GO:0044015 histone H2BK12 acetyltransferase activity 6/2108 22/18639 0.272727272727273 2.41146282559945 0.0314399079183341 0.183373650124668 GO:0044016 histone H3K4 acetyltransferase activity 6/2108 22/18639 0.272727272727273 2.41146282559945 0.0314399079183341 0.183373650124668 GO:0044017 histone H3K27 acetyltransferase activity 6/2108 22/18639 0.272727272727273 2.41146282559945 0.0314399079183341 0.183373650124668 GO:0044018 histone H3K36 acetyltransferase activity 6/2108 22/18639 0.272727272727273 2.41146282559945 0.0314399079183341 0.183373650124668 GO:0140908 histone H3K122 acetyltransferase activity 6/2108 22/18639 0.272727272727273 2.41146282559945 0.0314399079183341 0.183373650124668 GO:0034212 protein N-acetyltransferase activity 11/2108 53/18639 0.207547169811321 1.83513837671405 0.0326674426016111 0.189200093583024 GO:0051019 mitogen-activated protein kinase binding 7/2108 28/18639 0.25 2.21050759013283 0.0327584621490878 0.189200093583024 GO:0001221 transcription coregulator binding 20/2108 115/18639 0.173913043478261 1.53774441052718 0.0330474137449231 0.189942416864024 GO:0001784 phosphotyrosine residue binding 10/2108 47/18639 0.212765957446809 1.88128305543219 0.0347782542047716 0.197968523934854 GO:0061733 protein-lysine-acetyltransferase activity 10/2108 47/18639 0.212765957446809 1.88128305543219 0.0347782542047716 0.197968523934854 GO:0008429 phosphatidylethanolamine binding 5/2108 17/18639 0.294117647058824 2.60059716486215 0.0356058495000641 0.200749170514647 GO:1901567 fatty acid derivative binding 5/2108 17/18639 0.294117647058824 2.60059716486215 0.0356058495000641 0.200749170514647 GO:0003684 damaged DNA binding 14/2108 74/18639 0.189189189189189 1.67281655469511 0.0362779307824155 0.203569052352512 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 9/2108 41/18639 0.219512195121951 1.94093349377517 0.036716147343506 0.204609461602949 GO:0016651 oxidoreductase activity, acting on NAD(P)H 16/2108 88/18639 0.181818181818182 1.60764188373297 0.0368825705303577 0.204609461602949 GO:0003925 G protein activity 11/2108 54/18639 0.203703703703704 1.80115433270082 0.0369817776883708 0.204609461602949 GO:0005095 GTPase inhibitor activity 4/2108 12/18639 0.333333333333333 2.94734345351044 0.0383299286792085 0.20817722732194 GO:0035014 phosphatidylinositol 3-kinase regulator activity 4/2108 12/18639 0.333333333333333 2.94734345351044 0.0383299286792085 0.20817722732194 GO:0035197 siRNA binding 4/2108 12/18639 0.333333333333333 2.94734345351044 0.0383299286792085 0.20817722732194 GO:0045295 gamma-catenin binding 4/2108 12/18639 0.333333333333333 2.94734345351044 0.0383299286792085 0.20817722732194 GO:0044013 histone H2B acetyltransferase activity 6/2108 23/18639 0.260869565217391 2.30661661579078 0.0385903984017048 0.208634847979993 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 7/2108 29/18639 0.241379310344828 2.13428319047308 0.0391048058396554 0.209502670199783 GO:0097472 cyclin-dependent protein kinase activity 7/2108 29/18639 0.241379310344828 2.13428319047308 0.0391048058396554 0.209502670199783 GO:0005548 phospholipid transporter activity 13/2108 68/18639 0.191176470588235 1.6903881571604 0.0395347077005591 0.209520788445042 GO:0032934 sterol binding 13/2108 68/18639 0.191176470588235 1.6903881571604 0.0395347077005591 0.209520788445042 GO:0140693 molecular condensate scaffold activity 10/2108 48/18639 0.208333333333333 1.84208965844402 0.039639068084197 0.209520788445042 GO:0004402 histone acetyltransferase activity 9/2108 42/18639 0.214285714285714 1.89472079154242 0.0422109108635742 0.222123193166542 GO:0015078 proton transmembrane transporter activity 29/2108 185/18639 0.156756756756757 1.38604800246166 0.0431388520795957 0.226001773726731 GO:0019209 kinase activator activity 24/2108 148/18639 0.162162162162162 1.43384276116724 0.0441086915600502 0.230064717211892 GO:0004706 JUN kinase kinase kinase activity 5/2108 18/18639 0.277777777777778 2.45611954459203 0.0448457300475341 0.231866132647513 GO:0070628 proteasome binding 5/2108 18/18639 0.277777777777778 2.45611954459203 0.0448457300475341 0.231866132647513 GO:0032452 histone demethylase activity 7/2108 30/18639 0.233333333333333 2.06314041745731 0.0462033312973099 0.236817074701363 GO:0051721 protein phosphatase 2A binding 7/2108 30/18639 0.233333333333333 2.06314041745731 0.0462033312973099 0.236817074701363 GO:0043998 histone H2A acetyltransferase activity 6/2108 24/18639 0.25 2.21050759013283 0.0466954740724982 0.237285155801879 GO:0048027 mRNA 5'-UTR binding 6/2108 24/18639 0.25 2.21050759013283 0.0466954740724982 0.237285155801879 GO:0008170 N-methyltransferase activity 17/2108 98/18639 0.173469387755102 1.53382159315339 0.0476717374733341 0.241210842600118 GO:0008200 ion channel inhibitor activity 9/2108 43/18639 0.209302325581395 1.85065751732051 0.0482324538057813 0.243009469387426 GO:0032182 ubiquitin-like protein binding 20/2108 120/18639 0.166666666666667 1.47367172675522 0.0487739273146298 0.244696313307295 GO:0140104 molecular carrier activity 37/2108 249/18639 0.14859437751004 1.31387599734803 0.0504652895857496 0.24933346952387 GO:0004535 poly(A)-specific ribonuclease activity 4/2108 13/18639 0.307692307692308 2.72062472631733 0.0505405681467305 0.24933346952387 GO:0140333 glycerophospholipid flippase activity 4/2108 13/18639 0.307692307692308 2.72062472631733 0.0505405681467305 0.24933346952387 GO:0140852 histone ubiquitin ligase activity 4/2108 13/18639 0.307692307692308 2.72062472631733 0.0505405681467305 0.24933346952387 GO:0044325 transmembrane transporter binding 22/2108 136/18639 0.161764705882353 1.43032844067418 0.0533652013529723 0.261324205443168 GO:0015399 primary active transmembrane transporter activity 26/2108 166/18639 0.156626506024096 1.384896321529 0.0536319518204121 0.261324205443168 GO:0019001 guanyl nucleotide binding 56/2108 400/18639 0.14 1.23788425047438 0.0538793928022985 0.261324205443168 GO:0032561 guanyl ribonucleotide binding 56/2108 400/18639 0.14 1.23788425047438 0.0538793928022985 0.261324205443168 GO:0140457 protein demethylase activity 7/2108 31/18639 0.225806451612903 1.99658750076513 0.0540746877817366 0.261324205443168 GO:0035591 signaling adaptor activity 21/2108 129/18639 0.162790697674419 1.43940029124928 0.0548702319586583 0.262298160688054 GO:0042800 histone H3K4 methyltransferase activity 5/2108 19/18639 0.263157894736842 2.32685009487666 0.0553839021723088 0.262298160688054 GO:0050145 nucleoside monophosphate kinase activity 5/2108 19/18639 0.263157894736842 2.32685009487666 0.0553839021723088 0.262298160688054 GO:0120227 acyl-CoA binding 5/2108 19/18639 0.263157894736842 2.32685009487666 0.0553839021723088 0.262298160688054 GO:1990380 K48-linked deubiquitinase activity 5/2108 19/18639 0.263157894736842 2.32685009487666 0.0553839021723088 0.262298160688054 GO:0016922 nuclear receptor binding 22/2108 137/18639 0.160583941605839 1.41988808709262 0.0570615616660089 0.269166888496233 GO:0101005 deubiquitinase activity 19/2108 115/18639 0.165217391304348 1.46085719000082 0.0578225832799927 0.271674359537743 GO:0008408 3'-5' exonuclease activity 11/2108 58/18639 0.189655172413793 1.67693679251456 0.0581922432247856 0.272330497937336 GO:0046332 SMAD binding 14/2108 79/18639 0.177215189873418 1.56694208920808 0.0584719463196623 0.272562143474331 GO:0099106 ion channel regulator activity 25/2108 160/18639 0.15625 1.38156724383302 0.0588983677836345 0.273473205709111 GO:0004843 cysteine-type deubiquitinase activity 18/2108 108/18639 0.166666666666667 1.47367172675522 0.0592365996132044 0.27396927321107 GO:0016247 channel regulator activity 26/2108 168/18639 0.154761904761905 1.36840946055842 0.0604353033849285 0.278425677851188 GO:0030515 snoRNA binding 7/2108 32/18639 0.21875 1.93419414136622 0.0627331291534939 0.287891569448592 GO:0048306 calcium-dependent protein binding 14/2108 80/18639 0.175 1.54735531309298 0.0638191177577924 0.291744538321337 GO:0032036 myosin heavy chain binding 4/2108 14/18639 0.285714285714286 2.52629438872323 0.0646212854702093 0.293147900370605 GO:0071933 Arp2/3 complex binding 4/2108 14/18639 0.285714285714286 2.52629438872323 0.0646212854702093 0.293147900370605 GO:0030295 protein kinase activator activity 22/2108 139/18639 0.158273381294964 1.39945804267402 0.0649883475381608 0.293687799561765 GO:0141108 transporter regulator activity 26/2108 170/18639 0.152941176470588 1.35231052572832 0.0678277291969976 0.303573320492716 GO:0033192 calmodulin-dependent protein phosphatase activity 14/2108 81/18639 0.172839506172839 1.52825216107949 0.0694834204843971 0.303573320492716 GO:0140791 histone H2AXS140 phosphatase activity 14/2108 81/18639 0.172839506172839 1.52825216107949 0.0694834204843971 0.303573320492716 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 14/2108 81/18639 0.172839506172839 1.52825216107949 0.0694834204843971 0.303573320492716 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 14/2108 81/18639 0.172839506172839 1.52825216107949 0.0694834204843971 0.303573320492716 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 14/2108 81/18639 0.172839506172839 1.52825216107949 0.0694834204843971 0.303573320492716 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 14/2108 81/18639 0.172839506172839 1.52825216107949 0.0694834204843971 0.303573320492716 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 14/2108 81/18639 0.172839506172839 1.52825216107949 0.0694834204843971 0.303573320492716 GO:1990439 MAP kinase serine/threonine phosphatase activity 14/2108 81/18639 0.172839506172839 1.52825216107949 0.0694834204843971 0.303573320492716 GO:0004722 protein serine/threonine phosphatase activity 17/2108 103/18639 0.16504854368932 1.45936423426245 0.0704066968041228 0.306476209617946 GO:0005543 phospholipid binding 67/2108 497/18639 0.134808853118712 1.19198397214406 0.0723090917779759 0.313604266172613 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 14/2108 82/18639 0.170731707317073 1.50961493960291 0.0754692831592518 0.324354723158517 GO:0033549 MAP kinase phosphatase activity 14/2108 82/18639 0.170731707317073 1.50961493960291 0.0754692831592518 0.324354723158517 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 8/2108 40/18639 0.2 1.76840607210626 0.0758836641173221 0.324354723158517 GO:0050997 quaternary ammonium group binding 8/2108 40/18639 0.2 1.76840607210626 0.0758836641173221 0.324354723158517 GO:0008266 poly(U) RNA binding 6/2108 27/18639 0.222222222222222 1.96489563567362 0.07690790576322 0.326376202235314 GO:0015252 proton channel activity 6/2108 27/18639 0.222222222222222 1.96489563567362 0.07690790576322 0.326376202235314 GO:0140938 histone H3 methyltransferase activity 9/2108 47/18639 0.191489361702128 1.69315474988897 0.0778331620877052 0.329123085399439 GO:0015485 cholesterol binding 10/2108 54/18639 0.185185185185185 1.63741302972802 0.0785936685927679 0.330833090355841 GO:0043022 ribosome binding 18/2108 112/18639 0.160714285714286 1.42104059365682 0.0787963948313742 0.330833090355841 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 5/2108 21/18639 0.238095238095238 2.10524532393603 0.08035383137382 0.333332168451645 GO:0004865 protein serine/threonine phosphatase inhibitor activity 4/2108 15/18639 0.266666666666667 2.35787476280835 0.0805177366361238 0.333332168451645 GO:0005523 tropomyosin binding 4/2108 15/18639 0.266666666666667 2.35787476280835 0.0805177366361238 0.333332168451645 GO:0061578 K63-linked deubiquitinase activity 4/2108 15/18639 0.266666666666667 2.35787476280835 0.0805177366361238 0.333332168451645 GO:0140098 catalytic activity, acting on RNA 53/2108 387/18639 0.136950904392765 1.21092405454305 0.0809854138025668 0.334100104328359 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 14/2108 83/18639 0.168674698795181 1.49142680780046 0.0817802038335255 0.336207504648938 GO:0016877 ligase activity, forming carbon-sulfur bonds 8/2108 41/18639 0.195121951219512 1.72527421668904 0.0853788196988532 0.348581112149801 GO:0042169 SH2 domain binding 8/2108 41/18639 0.195121951219512 1.72527421668904 0.0853788196988532 0.348581112149801 GO:0140313 molecular sequestering activity 10/2108 55/18639 0.181818181818182 1.60764188373297 0.0867968820007228 0.351793973392324 GO:0004540 RNA nuclease activity 19/2108 121/18639 0.15702479338843 1.38841799049665 0.0869582284532548 0.351793973392324 GO:0000149 SNARE binding 17/2108 106/18639 0.160377358490566 1.4180614729154 0.0870571234830666 0.351793973392324 GO:0004527 exonuclease activity 14/2108 84/18639 0.166666666666667 1.47367172675522 0.0884187198465299 0.353406768876625 GO:0017018 myosin phosphatase activity 14/2108 84/18639 0.166666666666667 1.47367172675522 0.0884187198465299 0.353406768876625 GO:0046875 ephrin receptor binding 6/2108 28/18639 0.214285714285714 1.89472079154242 0.0889486631125289 0.353406768876625 GO:0097718 disordered domain specific binding 6/2108 28/18639 0.214285714285714 1.89472079154242 0.0889486631125289 0.353406768876625 GO:0141052 histone H3 demethylase activity 6/2108 28/18639 0.214285714285714 1.89472079154242 0.0889486631125289 0.353406768876625 GO:0008140 cAMP response element binding protein binding 3/2108 10/18639 0.3 2.65260910815939 0.0944512231874596 0.360683250378046 GO:0016303 1-phosphatidylinositol-3-kinase activity 3/2108 10/18639 0.3 2.65260910815939 0.0944512231874596 0.360683250378046 GO:0016868 intramolecular phosphotransferase activity 3/2108 10/18639 0.3 2.65260910815939 0.0944512231874596 0.360683250378046 GO:0019911 structural constituent of myelin sheath 3/2108 10/18639 0.3 2.65260910815939 0.0944512231874596 0.360683250378046 GO:0031996 thioesterase binding 3/2108 10/18639 0.3 2.65260910815939 0.0944512231874596 0.360683250378046 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 3/2108 10/18639 0.3 2.65260910815939 0.0944512231874596 0.360683250378046 GO:0045322 unmethylated CpG binding 3/2108 10/18639 0.3 2.65260910815939 0.0944512231874596 0.360683250378046 GO:0047429 nucleoside triphosphate diphosphatase activity 3/2108 10/18639 0.3 2.65260910815939 0.0944512231874596 0.360683250378046 GO:0051864 histone H3K36 demethylase activity 3/2108 10/18639 0.3 2.65260910815939 0.0944512231874596 0.360683250378046 GO:0099122 RNA polymerase II C-terminal domain binding 3/2108 10/18639 0.3 2.65260910815939 0.0944512231874596 0.360683250378046 GO:0140999 histone H3K4 trimethyltransferase activity 3/2108 10/18639 0.3 2.65260910815939 0.0944512231874596 0.360683250378046 GO:0046972 histone H4K16 acetyltransferase activity 5/2108 22/18639 0.227272727272727 2.00955235466621 0.094740279448963 0.360683250378046 GO:0140517 protein-RNA adaptor activity 5/2108 22/18639 0.227272727272727 2.00955235466621 0.094740279448963 0.360683250378046 GO:0019212 phosphatase inhibitor activity 10/2108 56/18639 0.178571428571429 1.57893399295202 0.0954977978111849 0.362401899386035 GO:0017124 SH3 domain binding 18/2108 115/18639 0.156521739130435 1.38396996947447 0.0959837745929136 0.363082393348274 GO:0008296 3'-5'-DNA exonuclease activity 4/2108 16/18639 0.25 2.21050759013283 0.0981434731361309 0.366567420167757 GO:0097027 ubiquitin-protein transferase activator activity 4/2108 16/18639 0.25 2.21050759013283 0.0981434731361309 0.366567420167757 GO:0140327 flippase activity 4/2108 16/18639 0.25 2.21050759013283 0.0981434731361309 0.366567420167757 GO:0140328 floppase activity 4/2108 16/18639 0.25 2.21050759013283 0.0981434731361309 0.366567420167757 GO:0046982 protein heterodimerization activity 50/2108 369/18639 0.13550135501355 1.19810709492294 0.100672424796263 0.374830663392375 GO:0003785 actin monomer binding 6/2108 29/18639 0.206896551724138 1.82938559183406 0.101951408488061 0.377220211405826 GO:0043236 laminin binding 6/2108 29/18639 0.206896551724138 1.82938559183406 0.101951408488061 0.377220211405826 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 14/2108 86/18639 0.162790697674419 1.43940029124928 0.102683746163946 0.378746278685708 GO:0005484 SNAP receptor activity 7/2108 36/18639 0.194444444444444 1.71928368121442 0.105295417908478 0.382422622097048 GO:0055106 ubiquitin-protein transferase regulator activity 7/2108 36/18639 0.194444444444444 1.71928368121442 0.105295417908478 0.382422622097048 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 7/2108 36/18639 0.194444444444444 1.71928368121442 0.105295417908478 0.382422622097048 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 7/2108 36/18639 0.194444444444444 1.71928368121442 0.105295417908478 0.382422622097048 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 7/2108 36/18639 0.194444444444444 1.71928368121442 0.105295417908478 0.382422622097048 GO:0016410 N-acyltransferase activity 15/2108 94/18639 0.159574468085106 1.41096229157415 0.106638451145166 0.386115982128064 GO:1990782 protein tyrosine kinase binding 18/2108 117/18639 0.153846153846154 1.36031236315866 0.10866620609077 0.392258500034976 GO:0003887 DNA-directed DNA polymerase activity 5/2108 23/18639 0.217391304347826 1.92218051315898 0.110337468628757 0.39468145878081 GO:0005158 insulin receptor binding 5/2108 23/18639 0.217391304347826 1.92218051315898 0.110337468628757 0.39468145878081 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 5/2108 23/18639 0.217391304347826 1.92218051315898 0.110337468628757 0.39468145878081 GO:0120013 lipid transfer activity 11/2108 65/18639 0.169230769230769 1.49634359947453 0.111795885939979 0.398693761906432 GO:0000049 tRNA binding 13/2108 80/18639 0.1625 1.43682993358634 0.113997539859491 0.400373991635732 GO:0008276 protein methyltransferase activity 15/2108 95/18639 0.157894736842105 1.396110056926 0.114093659383596 0.400373991635732 GO:0140597 protein carrier chaperone 27/2108 188/18639 0.143617021276596 1.26986606241673 0.114807804266658 0.400373991635732 GO:0008187 poly-pyrimidine tract binding 6/2108 30/18639 0.2 1.76840607210626 0.115888427785749 0.400373991635732 GO:0031210 phosphatidylcholine binding 6/2108 30/18639 0.2 1.76840607210626 0.115888427785749 0.400373991635732 GO:0005048 signal sequence binding 9/2108 51/18639 0.176470588235294 1.56035829891729 0.116482035549838 0.400373991635732 GO:0030544 Hsp70 protein binding 9/2108 51/18639 0.176470588235294 1.56035829891729 0.116482035549838 0.400373991635732 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 4/2108 17/18639 0.235294117647059 2.08047773188972 0.117385818870305 0.400373991635732 GO:0019198 transmembrane receptor protein phosphatase activity 4/2108 17/18639 0.235294117647059 2.08047773188972 0.117385818870305 0.400373991635732 GO:0032977 membrane insertase activity 4/2108 17/18639 0.235294117647059 2.08047773188972 0.117385818870305 0.400373991635732 GO:0043014 alpha-tubulin binding 8/2108 44/18639 0.181818181818182 1.60764188373297 0.117804405130204 0.400373991635732 GO:0004197 cysteine-type endopeptidase activity 14/2108 88/18639 0.159090909090909 1.40668664826634 0.118264692453931 0.400373991635732 GO:0051087 protein-folding chaperone binding 20/2108 134/18639 0.149253731343284 1.3197060239599 0.119277146941723 0.400373991635732 GO:0008172 S-methyltransferase activity 3/2108 11/18639 0.272727272727273 2.41146282559945 0.119368259330586 0.400373991635732 GO:0008432 JUN kinase binding 3/2108 11/18639 0.272727272727273 2.41146282559945 0.119368259330586 0.400373991635732 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 3/2108 11/18639 0.272727272727273 2.41146282559945 0.119368259330586 0.400373991635732 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 3/2108 11/18639 0.272727272727273 2.41146282559945 0.119368259330586 0.400373991635732 GO:0019107 myristoyltransferase activity 3/2108 11/18639 0.272727272727273 2.41146282559945 0.119368259330586 0.400373991635732 GO:0019206 nucleoside kinase activity 3/2108 11/18639 0.272727272727273 2.41146282559945 0.119368259330586 0.400373991635732 GO:0019215 intermediate filament binding 3/2108 11/18639 0.272727272727273 2.41146282559945 0.119368259330586 0.400373991635732 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 3/2108 11/18639 0.272727272727273 2.41146282559945 0.119368259330586 0.400373991635732 GO:0030971 receptor tyrosine kinase binding 13/2108 81/18639 0.160493827160494 1.41909129243095 0.122507592092965 0.409742906887205 GO:0001091 RNA polymerase II general transcription initiation factor binding 5/2108 24/18639 0.208333333333333 1.84208965844402 0.127085361933035 0.420304660694732 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 5/2108 24/18639 0.208333333333333 1.84208965844402 0.127085361933035 0.420304660694732 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 5/2108 24/18639 0.208333333333333 1.84208965844402 0.127085361933035 0.420304660694732 GO:0070840 dynein complex binding 5/2108 24/18639 0.208333333333333 1.84208965844402 0.127085361933035 0.420304660694732 GO:0140303 intramembrane lipid transporter activity 8/2108 45/18639 0.177777777777778 1.5719165085389 0.129889430459588 0.427191758450251 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 24/2108 167/18639 0.143712574850299 1.27071095001648 0.130126296372057 0.427191758450251 GO:0005096 GTPase activator activity 37/2108 271/18639 0.136531365313653 1.20721447726811 0.130250189865321 0.427191758450251 GO:0016779 nucleotidyltransferase activity 20/2108 136/18639 0.147058823529412 1.30029858243107 0.132780135903007 0.434286411351271 GO:0003725 double-stranded RNA binding 12/2108 75/18639 0.16 1.41472485768501 0.136303760170958 0.444583063477726 GO:0003697 single-stranded DNA binding 18/2108 121/18639 0.148760330578512 1.31534335941788 0.136967168270366 0.445519580308004 GO:0004864 protein phosphatase inhibitor activity 9/2108 53/18639 0.169811320754717 1.50147685367513 0.139121190105728 0.450053248866616 GO:0005246 calcium channel regulator activity 9/2108 53/18639 0.169811320754717 1.50147685367513 0.139121190105728 0.450053248866616 GO:1990841 promoter-specific chromatin binding 11/2108 68/18639 0.161764705882353 1.43032844067418 0.141306943177052 0.455878530576648 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 5/2108 25/18639 0.2 1.76840607210626 0.144912353987201 0.458608502029438 GO:0017025 TBP-class protein binding 5/2108 25/18639 0.2 1.76840607210626 0.144912353987201 0.458608502029438 GO:0017056 structural constituent of nuclear pore 5/2108 25/18639 0.2 1.76840607210626 0.144912353987201 0.458608502029438 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 7/2108 39/18639 0.179487179487179 1.58703109035177 0.145229370397779 0.458608502029438 GO:0019905 syntaxin binding 10/2108 61/18639 0.163934426229508 1.44951317385759 0.14631587983777 0.458608502029438 GO:0004859 phospholipase inhibitor activity 3/2108 12/18639 0.25 2.21050759013283 0.146381036214378 0.458608502029438 GO:0034452 dynactin binding 3/2108 12/18639 0.25 2.21050759013283 0.146381036214378 0.458608502029438 GO:0043047 single-stranded telomeric DNA binding 3/2108 12/18639 0.25 2.21050759013283 0.146381036214378 0.458608502029438 GO:1990817 poly(A) RNA polymerase activity 3/2108 12/18639 0.25 2.21050759013283 0.146381036214378 0.458608502029438 GO:0051059 NF-kappaB binding 6/2108 32/18639 0.1875 1.65788069259962 0.146413862978993 0.458608502029438 GO:0120015 sterol transfer activity 6/2108 32/18639 0.1875 1.65788069259962 0.146413862978993 0.458608502029438 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 9/2108 54/18639 0.166666666666667 1.47367172675522 0.151226694408319 0.471051021922379 GO:0002039 p53 binding 11/2108 69/18639 0.159420289855072 1.40959904298325 0.15197761011347 0.471051021922379 GO:0008080 N-acetyltransferase activity 11/2108 69/18639 0.159420289855072 1.40959904298325 0.15197761011347 0.471051021922379 GO:0016279 protein-lysine N-methyltransferase activity 11/2108 69/18639 0.159420289855072 1.40959904298325 0.15197761011347 0.471051021922379 GO:0035091 phosphatidylinositol binding 38/2108 284/18639 0.133802816901408 1.18308856936687 0.154807640360692 0.478569833386579 GO:0061749 forked DNA-dependent helicase activity 8/2108 47/18639 0.170212765957447 1.50502644434575 0.155866634144104 0.479340506043166 GO:1990518 single-stranded 3'-5' DNA helicase activity 8/2108 47/18639 0.170212765957447 1.50502644434575 0.155866634144104 0.479340506043166 GO:0051540 metal cluster binding 12/2108 77/18639 0.155844155844156 1.3779787574854 0.156459098360278 0.479915990825308 GO:0015036 disulfide oxidoreductase activity 7/2108 40/18639 0.175 1.54735531309298 0.159939065669392 0.484662242910121 GO:0032451 demethylase activity 7/2108 40/18639 0.175 1.54735531309298 0.159939065669392 0.484662242910121 GO:0061791 GTPase motor activity 7/2108 40/18639 0.175 1.54735531309298 0.159939065669392 0.484662242910121 GO:1990606 membrane scission GTPase motor activity 7/2108 40/18639 0.175 1.54735531309298 0.159939065669392 0.484662242910121 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 4/2108 19/18639 0.210526315789474 1.86148007590133 0.160172266897059 0.484662242910121 GO:0004713 protein tyrosine kinase activity 20/2108 140/18639 0.142857142857143 1.26314719436162 0.162336953155 0.484662242910121 GO:0019956 chemokine binding 6/2108 33/18639 0.181818181818182 1.60764188373297 0.162908856043609 0.484662242910121 GO:0140311 protein sequestering activity 6/2108 33/18639 0.181818181818182 1.60764188373297 0.162908856043609 0.484662242910121 GO:0140416 transcription regulator inhibitor activity 6/2108 33/18639 0.181818181818182 1.60764188373297 0.162908856043609 0.484662242910121 GO:0016278 lysine N-methyltransferase activity 11/2108 70/18639 0.157142857142857 1.38946191379778 0.163047656438059 0.484662242910121 GO:0004112 cyclic-nucleotide phosphodiesterase activity 5/2108 26/18639 0.192307692307692 1.70039045394833 0.163737244226392 0.484662242910121 GO:0004529 DNA exonuclease activity 5/2108 26/18639 0.192307692307692 1.70039045394833 0.163737244226392 0.484662242910121 GO:0052742 phosphatidylinositol kinase activity 5/2108 26/18639 0.192307692307692 1.70039045394833 0.163737244226392 0.484662242910121 GO:0070412 R-SMAD binding 5/2108 26/18639 0.192307692307692 1.70039045394833 0.163737244226392 0.484662242910121 GO:0140097 catalytic activity, acting on DNA 44/2108 336/18639 0.130952380952381 1.15788492816481 0.168926607612733 0.497369457110504 GO:0009378 four-way junction helicase activity 8/2108 48/18639 0.166666666666667 1.47367172675522 0.16971052421676 0.497369457110504 GO:0036121 double-stranded DNA helicase activity 8/2108 48/18639 0.166666666666667 1.47367172675522 0.16971052421676 0.497369457110504 GO:0043138 3'-5' DNA helicase activity 8/2108 48/18639 0.166666666666667 1.47367172675522 0.16971052421676 0.497369457110504 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 3/2108 13/18639 0.230769230769231 2.04046854473799 0.175133176634672 0.506202463858741 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 3/2108 13/18639 0.230769230769231 2.04046854473799 0.175133176634672 0.506202463858741 GO:0043560 insulin receptor substrate binding 3/2108 13/18639 0.230769230769231 2.04046854473799 0.175133176634672 0.506202463858741 GO:0089720 caspase binding 3/2108 13/18639 0.230769230769231 2.04046854473799 0.175133176634672 0.506202463858741 GO:0140410 monoatomic cation:bicarbonate symporter activity 3/2108 13/18639 0.230769230769231 2.04046854473799 0.175133176634672 0.506202463858741 GO:0017080 sodium channel regulator activity 7/2108 41/18639 0.170731707317073 1.50961493960291 0.175289704545679 0.506202463858741 GO:0030332 cyclin binding 6/2108 34/18639 0.176470588235294 1.56035829891729 0.180153103411523 0.51898120301519 GO:0016004 phospholipase activator activity 4/2108 20/18639 0.2 1.76840607210626 0.183409171190749 0.52598034573091 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 5/2108 27/18639 0.185185185185185 1.63741302972802 0.183471184786204 0.52598034573091 GO:1902936 phosphatidylinositol bisphosphate binding 16/2108 111/18639 0.144144144144144 1.27452689881532 0.185363889210575 0.530122813587732 GO:0016859 cis-trans isomerase activity 7/2108 42/18639 0.166666666666667 1.47367172675522 0.191240450511031 0.545611309409785 GO:0005154 epidermal growth factor receptor binding 6/2108 35/18639 0.171428571428571 1.51577663323394 0.198086328048267 0.563784164445067 GO:0061134 peptidase regulator activity 30/2108 226/18639 0.132743362831858 1.17372084431832 0.200118545015515 0.565216221967471 GO:0004866 endopeptidase inhibitor activity 22/2108 161/18639 0.136645962732919 1.2082277511285 0.202306250432644 0.565216221967471 GO:0003727 single-stranded RNA binding 13/2108 89/18639 0.146067415730337 1.29153252457199 0.20270414237671 0.565216221967471 GO:0008094 ATP-dependent activity, acting on DNA 28/2108 210/18639 0.133333333333333 1.17893738140417 0.202974824474281 0.565216221967471 GO:0061775 cohesin loader activity 21/2108 153/18639 0.137254901960784 1.213612010269 0.203122370328884 0.565216221967471 GO:0019789 SUMO transferase activity 5/2108 28/18639 0.178571428571429 1.57893399295202 0.20401955906309 0.565216221967471 GO:0046625 sphingolipid binding 5/2108 28/18639 0.178571428571429 1.57893399295202 0.20401955906309 0.565216221967471 GO:0005161 platelet-derived growth factor receptor binding 3/2108 14/18639 0.214285714285714 1.89472079154242 0.205272783315889 0.565216221967471 GO:0016530 metallochaperone activity 3/2108 14/18639 0.214285714285714 1.89472079154242 0.205272783315889 0.565216221967471 GO:0019992 diacylglycerol binding 3/2108 14/18639 0.214285714285714 1.89472079154242 0.205272783315889 0.565216221967471 GO:0032454 histone H3K9 demethylase activity 3/2108 14/18639 0.214285714285714 1.89472079154242 0.205272783315889 0.565216221967471 GO:0034236 protein kinase A catalytic subunit binding 3/2108 14/18639 0.214285714285714 1.89472079154242 0.205272783315889 0.565216221967471 GO:0042043 neurexin family protein binding 3/2108 14/18639 0.214285714285714 1.89472079154242 0.205272783315889 0.565216221967471 GO:0098847 sequence-specific single stranded DNA binding 3/2108 14/18639 0.214285714285714 1.89472079154242 0.205272783315889 0.565216221967471 GO:0035613 RNA stem-loop binding 4/2108 21/18639 0.19047619047619 1.68419625914882 0.207657486441791 0.570455832823853 GO:0035064 methylated histone binding 11/2108 74/18639 0.148648648648649 1.3143558644033 0.211042573987236 0.57841298055761 GO:0016830 carbon-carbon lyase activity 8/2108 51/18639 0.156862745098039 1.38698515459315 0.214311088108096 0.586014615057702 GO:0004869 cysteine-type endopeptidase inhibitor activity 6/2108 36/18639 0.166666666666667 1.47367172675522 0.216644510076224 0.589671494092528 GO:0045505 dynein intermediate chain binding 6/2108 36/18639 0.166666666666667 1.47367172675522 0.216644510076224 0.589671494092528 GO:0042054 histone methyltransferase activity 10/2108 67/18639 0.149253731343284 1.3197060239599 0.221870837566813 0.602511632291528 GO:0070851 growth factor receptor binding 19/2108 139/18639 0.136690647482014 1.20862285503665 0.22284514406575 0.603772655775396 GO:0030165 PDZ domain binding 12/2108 83/18639 0.144578313253012 1.27836583525754 0.225130887495428 0.604816247088551 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 5/2108 29/18639 0.172413793103448 1.52448799319505 0.225283757099554 0.604816247088551 GO:0035401 histone H3Y41 kinase activity 16/2108 115/18639 0.139130434782609 1.23019552842175 0.225378299019982 0.604816247088551 GO:0140801 histone H2AXY142 kinase activity 16/2108 115/18639 0.139130434782609 1.23019552842175 0.225378299019982 0.604816247088551 GO:0072341 modified amino acid binding 13/2108 91/18639 0.142857142857143 1.26314719436162 0.225784443592179 0.604816247088551 GO:0140713 histone chaperone activity 22/2108 164/18639 0.134146341463415 1.18612602397371 0.227853705634876 0.608981461561385 GO:0005080 protein kinase C binding 8/2108 52/18639 0.153846153846154 1.36031236315866 0.230088671090083 0.612190981057659 GO:0030159 signaling receptor complex adaptor activity 8/2108 52/18639 0.153846153846154 1.36031236315866 0.230088671090083 0.612190981057659 GO:0008970 phospholipase A1 activity 4/2108 22/18639 0.181818181818182 1.60764188373297 0.232750199106864 0.61586955572196 GO:0031683 G-protein beta/gamma-subunit complex binding 4/2108 22/18639 0.181818181818182 1.60764188373297 0.232750199106864 0.61586955572196 GO:0017081 chloride channel regulator activity 3/2108 15/18639 0.2 1.76840607210626 0.23646154498583 0.61586955572196 GO:0031005 filamin binding 3/2108 15/18639 0.2 1.76840607210626 0.23646154498583 0.61586955572196 GO:0042809 nuclear vitamin D receptor binding 3/2108 15/18639 0.2 1.76840607210626 0.23646154498583 0.61586955572196 GO:0048531 beta-1,3-galactosyltransferase activity 3/2108 15/18639 0.2 1.76840607210626 0.23646154498583 0.61586955572196 GO:0055105 ubiquitin-protein transferase inhibitor activity 3/2108 15/18639 0.2 1.76840607210626 0.23646154498583 0.61586955572196 GO:0005496 steroid binding 15/2108 108/18639 0.138888888888889 1.22805977229602 0.236783616640338 0.61586955572196 GO:0051536 iron-sulfur cluster binding 11/2108 76/18639 0.144736842105263 1.27976755218216 0.237036006358707 0.61586955572196 GO:0140034 methylation-dependent protein binding 11/2108 76/18639 0.144736842105263 1.27976755218216 0.237036006358707 0.61586955572196 GO:0051117 ATPase binding 12/2108 84/18639 0.142857142857143 1.26314719436162 0.237631045440647 0.61586955572196 GO:0043178 alcohol binding 13/2108 92/18639 0.141304347826087 1.24941733355334 0.237713164666331 0.61586955572196 GO:0005544 calcium-dependent phospholipid binding 8/2108 53/18639 0.150943396226415 1.33464609215567 0.246260667709524 0.633421606899095 GO:0051018 protein kinase A binding 8/2108 53/18639 0.150943396226415 1.33464609215567 0.246260667709524 0.633421606899095 GO:0140296 general transcription initiation factor binding 8/2108 53/18639 0.150943396226415 1.33464609215567 0.246260667709524 0.633421606899095 GO:0001968 fibronectin binding 5/2108 30/18639 0.166666666666667 1.47367172675522 0.247162822962316 0.633421606899095 GO:0070566 adenylyltransferase activity 5/2108 30/18639 0.166666666666667 1.47367172675522 0.247162822962316 0.633421606899095 GO:0140658 ATP-dependent chromatin remodeler activity 21/2108 158/18639 0.132911392405063 1.17520656690606 0.247743932496293 0.633539559558554 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 4/2108 23/18639 0.173913043478261 1.53774441052718 0.25852130026015 0.649551378916809 GO:0017134 fibroblast growth factor binding 4/2108 23/18639 0.173913043478261 1.53774441052718 0.25852130026015 0.649551378916809 GO:0043274 phospholipase binding 4/2108 23/18639 0.173913043478261 1.53774441052718 0.25852130026015 0.649551378916809 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 4/2108 23/18639 0.173913043478261 1.53774441052718 0.25852130026015 0.649551378916809 GO:0061135 endopeptidase regulator activity 24/2108 184/18639 0.130434782608696 1.15330830789539 0.258761127891757 0.649551378916809 GO:0004518 nuclease activity 27/2108 209/18639 0.129186602870813 1.14227186475763 0.259296100185008 0.649551378916809 GO:0000510 H3-H4 histone complex chaperone activity 20/2108 151/18639 0.132450331125828 1.17112984907699 0.259491387016597 0.649551378916809 GO:0140584 chromatin extrusion motor activity 20/2108 151/18639 0.132450331125828 1.17112984907699 0.259491387016597 0.649551378916809 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 20/2108 151/18639 0.132450331125828 1.17112984907699 0.259491387016597 0.649551378916809 GO:0140849 ATP-dependent H2AZ histone chaperone activity 20/2108 151/18639 0.132450331125828 1.17112984907699 0.259491387016597 0.649551378916809 GO:0030276 clathrin binding 7/2108 46/18639 0.152173913043478 1.34552635921129 0.260127261497167 0.649769362051996 GO:0003689 DNA clamp loader activity 21/2108 160/18639 0.13125 1.16051648481973 0.266645263599445 0.661539110018361 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 3/2108 16/18639 0.1875 1.65788069259962 0.268381100028069 0.661539110018361 GO:0004708 MAP kinase kinase activity 3/2108 16/18639 0.1875 1.65788069259962 0.268381100028069 0.661539110018361 GO:0017070 U6 snRNA binding 3/2108 16/18639 0.1875 1.65788069259962 0.268381100028069 0.661539110018361 GO:0043023 ribosomal large subunit binding 3/2108 16/18639 0.1875 1.65788069259962 0.268381100028069 0.661539110018361 GO:0055102 lipase inhibitor activity 3/2108 16/18639 0.1875 1.65788069259962 0.268381100028069 0.661539110018361 GO:0015616 DNA translocase activity 20/2108 152/18639 0.131578947368421 1.16342504743833 0.269308995801394 0.661539110018361 GO:0140674 ATP-dependent histone chaperone activity 20/2108 152/18639 0.131578947368421 1.16342504743833 0.269308995801394 0.661539110018361 GO:0030414 peptidase inhibitor activity 22/2108 169/18639 0.130177514792899 1.15103353805733 0.273366401256532 0.670115567469429 GO:0019838 growth factor binding 18/2108 136/18639 0.132352941176471 1.17026872418797 0.274660642805597 0.671897109673196 GO:0005178 integrin binding 21/2108 161/18639 0.130434782608696 1.15330830789539 0.276296115574466 0.674504331629211 GO:0005507 copper ion binding 9/2108 63/18639 0.142857142857143 1.26314719436162 0.279783825070548 0.681613269307672 GO:0060229 lipase activator activity 4/2108 24/18639 0.166666666666667 1.47367172675522 0.284808487925572 0.691010757589913 GO:0070300 phosphatidic acid binding 4/2108 24/18639 0.166666666666667 1.47367172675522 0.284808487925572 0.691010757589913 GO:0070717 poly-purine tract binding 5/2108 32/18639 0.15625 1.38156724383302 0.292358863432299 0.706434478171106 GO:0140142 nucleocytoplasmic carrier activity 5/2108 32/18639 0.15625 1.38156724383302 0.292358863432299 0.706434478171106 GO:0005092 GDP-dissociation inhibitor activity 3/2108 17/18639 0.176470588235294 1.56035829891729 0.300737231704733 0.720795308377335 GO:0048038 quinone binding 3/2108 17/18639 0.176470588235294 1.56035829891729 0.300737231704733 0.720795308377335 GO:0051787 misfolded protein binding 3/2108 17/18639 0.176470588235294 1.56035829891729 0.300737231704733 0.720795308377335 GO:0070402 NADPH binding 3/2108 17/18639 0.176470588235294 1.56035829891729 0.300737231704733 0.720795308377335 GO:0140101 catalytic activity, acting on a tRNA 18/2108 139/18639 0.129496402877698 1.1450111258242 0.306947437968745 0.722467912768804 GO:0008139 nuclear localization sequence binding 4/2108 25/18639 0.16 1.41472485768501 0.3114553705805 0.722467912768804 GO:0016504 peptidase activator activity 8/2108 57/18639 0.140350877192982 1.24098671726755 0.314104485182527 0.722467912768804 GO:0005516 calmodulin binding 26/2108 207/18639 0.1256038647343 1.11059318538074 0.314627159676854 0.722467912768804 GO:0000182 rDNA binding 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0001094 TFIID-class transcription factor complex binding 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0005528 FK506 binding 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0015279 store-operated calcium channel activity 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0030957 Tat protein binding 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0031434 mitogen-activated protein kinase kinase binding 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0031720 haptoglobin binding 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0042975 peroxisome proliferator activated receptor binding 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0043208 glycosphingolipid binding 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0043422 protein kinase B binding 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0051880 G-quadruplex DNA binding 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0070097 delta-catenin binding 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0070513 death domain binding 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0098505 G-rich strand telomeric DNA binding 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:1990757 ubiquitin ligase activator activity 2/2108 10/18639 0.2 1.76840607210626 0.314859326848566 0.722467912768804 GO:0060590 ATPase regulator activity 7/2108 49/18639 0.142857142857143 1.26314719436162 0.315731268784695 0.723067354431486 GO:0003678 DNA helicase activity 10/2108 74/18639 0.135135135135135 1.19486896763937 0.324713234016812 0.742201677752713 GO:0017116 single-stranded DNA helicase activity 8/2108 58/18639 0.137931034482759 1.21959039455604 0.331651889206907 0.753020308674129 GO:0000400 four-way junction DNA binding 3/2108 18/18639 0.166666666666667 1.47367172675522 0.333262366338888 0.753020308674129 GO:0008308 voltage-gated monoatomic anion channel activity 3/2108 18/18639 0.166666666666667 1.47367172675522 0.333262366338888 0.753020308674129 GO:0008409 5'-3' exonuclease activity 3/2108 18/18639 0.166666666666667 1.47367172675522 0.333262366338888 0.753020308674129 GO:0017128 phospholipid scramblase activity 3/2108 18/18639 0.166666666666667 1.47367172675522 0.333262366338888 0.753020308674129 GO:0050811 GABA receptor binding 3/2108 18/18639 0.166666666666667 1.47367172675522 0.333262366338888 0.753020308674129 GO:0019894 kinesin binding 6/2108 42/18639 0.142857142857143 1.26314719436162 0.337281089435161 0.756880459250301 GO:0034237 protein kinase A regulatory subunit binding 4/2108 26/18639 0.153846153846154 1.36031236315866 0.338313211735792 0.756880459250301 GO:0050681 nuclear androgen receptor binding 4/2108 26/18639 0.153846153846154 1.36031236315866 0.338313211735792 0.756880459250301 GO:0120014 phospholipid transfer activity 4/2108 26/18639 0.153846153846154 1.36031236315866 0.338313211735792 0.756880459250301 GO:0008376 acetylgalactosaminyltransferase activity 5/2108 34/18639 0.147058823529412 1.30029858243107 0.338806286657652 0.756880459250301 GO:0015035 protein-disulfide reductase activity 5/2108 34/18639 0.147058823529412 1.30029858243107 0.338806286657652 0.756880459250301 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 9/2108 67/18639 0.134328358208955 1.18773542156391 0.344772765135493 0.767313823158691 GO:0050840 extracellular matrix binding 9/2108 67/18639 0.134328358208955 1.18773542156391 0.344772765135493 0.767313823158691 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0008526 phosphatidylinositol transfer activity 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0032050 clathrin heavy chain binding 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0032794 GTPase activating protein binding 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0034511 U3 snoRNA binding 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0034713 type I transforming growth factor beta receptor binding 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0043522 leucine zipper domain binding 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0045294 alpha-catenin binding 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0048185 activin binding 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0050786 RAGE receptor binding 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0050998 nitric-oxide synthase binding 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0140031 phosphorylation-dependent protein binding 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0140537 transcription regulator activator activity 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:1990948 ubiquitin ligase inhibitor activity 2/2108 11/18639 0.181818181818182 1.60764188373297 0.358301786297007 0.771326027228466 GO:0034061 DNA polymerase activity 5/2108 35/18639 0.142857142857143 1.26314719436162 0.362259613092549 0.776521865887753 GO:0001671 ATPase activator activity 4/2108 27/18639 0.148148148148148 1.30993042378242 0.365242259900938 0.776521865887753 GO:0004364 glutathione transferase activity 4/2108 27/18639 0.148148148148148 1.30993042378242 0.365242259900938 0.776521865887753 GO:0004683 calcium/calmodulin-dependent protein kinase activity 4/2108 27/18639 0.148148148148148 1.30993042378242 0.365242259900938 0.776521865887753 GO:0005385 zinc ion transmembrane transporter activity 4/2108 27/18639 0.148148148148148 1.30993042378242 0.365242259900938 0.776521865887753 GO:0070003 threonine-type peptidase activity 3/2108 19/18639 0.157894736842105 1.396110056926 0.365716759984231 0.776521865887753 GO:0097001 ceramide binding 3/2108 19/18639 0.157894736842105 1.396110056926 0.365716759984231 0.776521865887753 GO:0008168 methyltransferase activity 25/2108 204/18639 0.122549019607843 1.0835821520259 0.365962163146424 0.776521865887753 GO:0016209 antioxidant activity 11/2108 86/18639 0.127906976744186 1.13095737169587 0.380375013585593 0.795993537911447 GO:0004867 serine-type endopeptidase inhibitor activity 12/2108 95/18639 0.126315789473684 1.1168880455408 0.388070415730957 0.795993537911447 GO:0050698 proteoglycan sulfotransferase activity 4/2108 28/18639 0.142857142857143 1.26314719436162 0.39211271004058 0.795993537911447 GO:0051537 2 iron, 2 sulfur cluster binding 4/2108 28/18639 0.142857142857143 1.26314719436162 0.39211271004058 0.795993537911447 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 4/2108 28/18639 0.142857142857143 1.26314719436162 0.39211271004058 0.795993537911447 GO:0016251 RNA polymerase II general transcription initiation factor activity 7/2108 53/18639 0.132075471698113 1.16781533063621 0.392468595841155 0.795993537911447 GO:0001972 retinoic acid binding 3/2108 20/18639 0.15 1.3263045540797 0.397888687418375 0.795993537911447 GO:0016505 peptidase activator activity involved in apoptotic process 3/2108 20/18639 0.15 1.3263045540797 0.397888687418375 0.795993537911447 GO:0030742 GTP-dependent protein binding 3/2108 20/18639 0.15 1.3263045540797 0.397888687418375 0.795993537911447 GO:0061608 nuclear import signal receptor activity 3/2108 20/18639 0.15 1.3263045540797 0.397888687418375 0.795993537911447 GO:0140939 histone H4 methyltransferase activity 3/2108 20/18639 0.15 1.3263045540797 0.397888687418375 0.795993537911447 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 32/2108 268/18639 0.119402985074627 1.05576481916792 0.399680149109638 0.795993537911447 GO:0003995 acyl-CoA dehydrogenase activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0004126 cytidine deaminase activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0004300 enoyl-CoA hydratase activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0005025 transforming growth factor beta receptor activity, type I 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0005026 transforming growth factor beta receptor activity, type II 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0005049 nuclear export signal receptor activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0005527 macrolide binding 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0015269 calcium-activated potassium channel activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0016273 arginine N-methyltransferase activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0016274 protein-arginine N-methyltransferase activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0016361 activin receptor activity, type I 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0016362 activin receptor activity, type II 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0016801 hydrolase activity, acting on ether bonds 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0016803 ether hydrolase activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0016840 carbon-nitrogen lyase activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0017002 activin receptor activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0035497 cAMP response element binding 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0070008 serine-type exopeptidase activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0097371 MDM2/MDM4 family protein binding 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/2108 12/18639 0.166666666666667 1.47367172675522 0.400685936313533 0.795993537911447 GO:0016835 carbon-oxygen lyase activity 10/2108 79/18639 0.126582278481013 1.11924434943434 0.403230124996113 0.799705976541705 GO:0022829 wide pore channel activity 5/2108 37/18639 0.135135135135135 1.19486896763937 0.409181095676464 0.810151199466445 GO:0001217 DNA-binding transcription repressor activity 33/2108 278/18639 0.118705035971223 1.04959353200552 0.41101412595769 0.811125225054688 GO:0016829 lyase activity 24/2108 200/18639 0.12 1.06104364326376 0.411043188372308 0.811125225054688 GO:0051861 glycolipid binding 4/2108 29/18639 0.137931034482759 1.21959039455604 0.418805342511144 0.823696886267764 GO:0106222 lncRNA binding 4/2108 29/18639 0.137931034482759 1.21959039455604 0.418805342511144 0.823696886267764 GO:0008013 beta-catenin binding 13/2108 106/18639 0.122641509433962 1.08439994987648 0.422420328208572 0.829428969484162 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 3/2108 21/18639 0.142857142857143 1.26314719436162 0.429593887581139 0.840725889084411 GO:0005123 death receptor binding 3/2108 21/18639 0.142857142857143 1.26314719436162 0.429593887581139 0.840725889084411 GO:0030527 structural constituent of chromatin 12/2108 98/18639 0.122448979591837 1.0826975951671 0.431154970769629 0.842388589754523 GO:0043531 ADP binding 5/2108 38/18639 0.131578947368421 1.16342504743833 0.432486357134603 0.843597770753492 GO:0005172 vascular endothelial growth factor receptor binding 2/2108 13/18639 0.153846153846154 1.36031236315866 0.441695528982417 0.847597254967879 GO:0019104 DNA N-glycosylase activity 2/2108 13/18639 0.153846153846154 1.36031236315866 0.441695528982417 0.847597254967879 GO:0019855 calcium channel inhibitor activity 2/2108 13/18639 0.153846153846154 1.36031236315866 0.441695528982417 0.847597254967879 GO:0030955 potassium ion binding 2/2108 13/18639 0.153846153846154 1.36031236315866 0.441695528982417 0.847597254967879 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 2/2108 13/18639 0.153846153846154 1.36031236315866 0.441695528982417 0.847597254967879 GO:0045159 myosin II binding 2/2108 13/18639 0.153846153846154 1.36031236315866 0.441695528982417 0.847597254967879 GO:0046974 histone H3K9 methyltransferase activity 2/2108 13/18639 0.153846153846154 1.36031236315866 0.441695528982417 0.847597254967879 GO:0070123 transforming growth factor beta receptor activity, type III 2/2108 13/18639 0.153846153846154 1.36031236315866 0.441695528982417 0.847597254967879 GO:0140666 annealing activity 2/2108 13/18639 0.153846153846154 1.36031236315866 0.441695528982417 0.847597254967879 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 2/2108 13/18639 0.153846153846154 1.36031236315866 0.441695528982417 0.847597254967879 GO:0001965 G-protein alpha-subunit binding 4/2108 30/18639 0.133333333333333 1.17893738140417 0.445211883980194 0.850211081665403 GO:0016769 transferase activity, transferring nitrogenous groups 4/2108 30/18639 0.133333333333333 1.17893738140417 0.445211883980194 0.850211081665403 GO:0035925 mRNA 3'-UTR AU-rich region binding 4/2108 30/18639 0.133333333333333 1.17893738140417 0.445211883980194 0.850211081665403 GO:0005319 lipid transporter activity 21/2108 178/18639 0.117977528089888 1.04316088523122 0.453175870559916 0.864026136462062 GO:0000217 DNA secondary structure binding 5/2108 39/18639 0.128205128205128 1.13359363596555 0.455588574495437 0.867229698074915 GO:0008093 cytoskeletal anchor activity 3/2108 22/18639 0.136363636363636 1.20573141279972 0.460674469971814 0.872701715914605 GO:0008649 rRNA methyltransferase activity 3/2108 22/18639 0.136363636363636 1.20573141279972 0.460674469971814 0.872701715914605 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 3/2108 22/18639 0.136363636363636 1.20573141279972 0.460674469971814 0.872701715914605 GO:0042826 histone deacetylase binding 15/2108 127/18639 0.118110236220472 1.04433429455094 0.47034179688182 0.884219329267426 GO:0016887 ATP hydrolysis activity 48/2108 417/18639 0.115107913669065 1.01778766739929 0.471209624190465 0.884219329267426 GO:0005164 tumor necrosis factor receptor binding 4/2108 31/18639 0.129032258064516 1.14090714329436 0.471235132405191 0.884219329267426 GO:0016878 acid-thiol ligase activity 4/2108 31/18639 0.129032258064516 1.14090714329436 0.471235132405191 0.884219329267426 GO:0047499 calcium-independent phospholipase A2 activity 4/2108 31/18639 0.129032258064516 1.14090714329436 0.471235132405191 0.884219329267426 GO:0070273 phosphatidylinositol-4-phosphate binding 4/2108 31/18639 0.129032258064516 1.14090714329436 0.471235132405191 0.884219329267426 GO:0016741 transferase activity, transferring one-carbon groups 25/2108 215/18639 0.116279069767442 1.02814306517806 0.473184748846455 0.886472694041459 GO:0005344 oxygen carrier activity 2/2108 14/18639 0.142857142857143 1.26314719436162 0.481099319926838 0.888645233687014 GO:0008474 palmitoyl-(protein) hydrolase activity 2/2108 14/18639 0.142857142857143 1.26314719436162 0.481099319926838 0.888645233687014 GO:0008494 translation activator activity 2/2108 14/18639 0.142857142857143 1.26314719436162 0.481099319926838 0.888645233687014 GO:0030983 mismatched DNA binding 2/2108 14/18639 0.142857142857143 1.26314719436162 0.481099319926838 0.888645233687014 GO:0046030 inositol trisphosphate phosphatase activity 2/2108 14/18639 0.142857142857143 1.26314719436162 0.481099319926838 0.888645233687014 GO:0061665 SUMO ligase activity 2/2108 14/18639 0.142857142857143 1.26314719436162 0.481099319926838 0.888645233687014 GO:0070742 C2H2 zinc finger domain binding 2/2108 14/18639 0.142857142857143 1.26314719436162 0.481099319926838 0.888645233687014 GO:0098599 palmitoyl hydrolase activity 2/2108 14/18639 0.142857142857143 1.26314719436162 0.481099319926838 0.888645233687014 GO:0098821 BMP receptor activity 2/2108 14/18639 0.142857142857143 1.26314719436162 0.481099319926838 0.888645233687014 GO:0051213 dioxygenase activity 11/2108 93/18639 0.118279569892473 1.04583154801983 0.485422502389013 0.89437073136526 GO:0061980 regulatory RNA binding 7/2108 58/18639 0.120689655172414 1.06714159523654 0.488192923934508 0.89437073136526 GO:0004602 glutathione peroxidase activity 3/2108 23/18639 0.130434782608696 1.15330830789539 0.490997445428563 0.89437073136526 GO:0008171 O-methyltransferase activity 3/2108 23/18639 0.130434782608696 1.15330830789539 0.490997445428563 0.89437073136526 GO:0042171 lysophosphatidic acid acyltransferase activity 3/2108 23/18639 0.130434782608696 1.15330830789539 0.490997445428563 0.89437073136526 GO:0071617 lysophospholipid acyltransferase activity 3/2108 23/18639 0.130434782608696 1.15330830789539 0.490997445428563 0.89437073136526 GO:0099186 structural constituent of postsynapse 3/2108 23/18639 0.130434782608696 1.15330830789539 0.490997445428563 0.89437073136526 GO:0140102 catalytic activity, acting on a rRNA 3/2108 23/18639 0.130434782608696 1.15330830789539 0.490997445428563 0.89437073136526 GO:0140103 catalytic activity, acting on a glycoprotein 3/2108 23/18639 0.130434782608696 1.15330830789539 0.490997445428563 0.89437073136526 GO:0008378 galactosyltransferase activity 4/2108 32/18639 0.125 1.10525379506641 0.496788885115604 0.900762695217266 GO:0031369 translation initiation factor binding 4/2108 32/18639 0.125 1.10525379506641 0.496788885115604 0.900762695217266 GO:0047498 calcium-dependent phospholipase A2 activity 4/2108 32/18639 0.125 1.10525379506641 0.496788885115604 0.900762695217266 GO:0001727 lipid kinase activity 5/2108 41/18639 0.121951219512195 1.07829638543065 0.500920810857179 0.906865810481498 GO:0032813 tumor necrosis factor receptor superfamily binding 6/2108 50/18639 0.12 1.06104364326376 0.504172776250848 0.91135964439848 GO:0051082 unfolded protein binding 14/2108 121/18639 0.115702479338843 1.0230448351028 0.506444616833176 0.913469512234246 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 7/2108 59/18639 0.11864406779661 1.04905444955456 0.506882997920524 0.913469512234246 GO:0140223 general transcription initiation factor activity 8/2108 68/18639 0.117647058823529 1.04023886594486 0.509226663315987 0.916298433687125 GO:0000774 adenyl-nucleotide exchange factor activity 2/2108 15/18639 0.133333333333333 1.17893738140417 0.518735900686992 0.921570304517302 GO:0010181 FMN binding 2/2108 15/18639 0.133333333333333 1.17893738140417 0.518735900686992 0.921570304517302 GO:0015556 C4-dicarboxylate transmembrane transporter activity 2/2108 15/18639 0.133333333333333 1.17893738140417 0.518735900686992 0.921570304517302 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/2108 15/18639 0.133333333333333 1.17893738140417 0.518735900686992 0.921570304517302 GO:0033130 acetylcholine receptor binding 2/2108 15/18639 0.133333333333333 1.17893738140417 0.518735900686992 0.921570304517302 GO:0047372 monoacylglycerol lipase activity 2/2108 15/18639 0.133333333333333 1.17893738140417 0.518735900686992 0.921570304517302 GO:0050700 CARD domain binding 2/2108 15/18639 0.133333333333333 1.17893738140417 0.518735900686992 0.921570304517302 GO:0051371 muscle alpha-actinin binding 2/2108 15/18639 0.133333333333333 1.17893738140417 0.518735900686992 0.921570304517302 GO:0030552 cAMP binding 3/2108 24/18639 0.125 1.10525379506641 0.520453010786133 0.921570304517302 GO:0050431 transforming growth factor beta binding 3/2108 24/18639 0.125 1.10525379506641 0.520453010786133 0.921570304517302 GO:0031072 heat shock protein binding 15/2108 131/18639 0.114503816793893 1.01244622448832 0.520718356184185 0.921570304517302 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 4/2108 33/18639 0.121212121212121 1.07176125582198 0.521797705658407 0.922102214178438 GO:0042056 chemoattractant activity 5/2108 42/18639 0.119047619047619 1.05262266196801 0.523034286725019 0.922909978364266 GO:0016597 amino acid binding 6/2108 51/18639 0.117647058823529 1.04023886594486 0.524209310873646 0.923606881063091 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 7/2108 60/18639 0.116666666666667 1.03157020872865 0.525336224176914 0.924217071954629 GO:0008081 phosphoric diester hydrolase activity 10/2108 87/18639 0.114942528735632 1.0163253287967 0.528481833712384 0.928371648539262 GO:0016407 acetyltransferase activity 11/2108 96/18639 0.114583333333333 1.01314931214421 0.529463569018726 0.928718319582477 GO:0016782 transferase activity, transferring sulphur-containing groups 8/2108 70/18639 0.114285714285714 1.01051775548929 0.543393243658132 0.951024601243833 GO:0004712 protein serine/threonine/tyrosine kinase activity 5/2108 43/18639 0.116279069767442 1.02814306517806 0.544711617506292 0.951024601243833 GO:0008375 acetylglucosaminyltransferase activity 5/2108 43/18639 0.116279069767442 1.02814306517806 0.544711617506292 0.951024601243833 GO:0016831 carboxy-lyase activity 4/2108 34/18639 0.117647058823529 1.04023886594486 0.546196561525174 0.951024601243833 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 4/2108 34/18639 0.117647058823529 1.04023886594486 0.546196561525174 0.951024601243833 GO:0019706 protein-cysteine S-palmitoyltransferase activity 3/2108 25/18639 0.12 1.06104364326376 0.548952688995993 0.951625159255132 GO:0019707 protein-cysteine S-acyltransferase activity 3/2108 25/18639 0.12 1.06104364326376 0.548952688995993 0.951625159255132 GO:0042974 nuclear retinoic acid receptor binding 3/2108 25/18639 0.12 1.06104364326376 0.548952688995993 0.951625159255132 GO:0005024 transforming growth factor beta receptor activity 2/2108 16/18639 0.125 1.10525379506641 0.554500872209696 0.955646335802445 GO:0005149 interleukin-1 receptor binding 2/2108 16/18639 0.125 1.10525379506641 0.554500872209696 0.955646335802445 GO:0005159 insulin-like growth factor receptor binding 2/2108 16/18639 0.125 1.10525379506641 0.554500872209696 0.955646335802445 GO:0030275 LRR domain binding 2/2108 16/18639 0.125 1.10525379506641 0.554500872209696 0.955646335802445 GO:0030547 signaling receptor inhibitor activity 5/2108 44/18639 0.113636363636364 1.0047761773331 0.565909367936145 0.973890540169179 GO:0004623 phospholipase A2 activity 4/2108 35/18639 0.114285714285714 1.01051775548929 0.569930361322932 0.979182274965199 GO:0005160 transforming growth factor beta receptor binding 3/2108 26/18639 0.115384615384615 1.020234272369 0.576427403421236 0.979182274965199 GO:0005227 calcium-activated cation channel activity 3/2108 26/18639 0.115384615384615 1.020234272369 0.576427403421236 0.979182274965199 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/2108 26/18639 0.115384615384615 1.020234272369 0.576427403421236 0.979182274965199 GO:0008143 poly(A) binding 3/2108 26/18639 0.115384615384615 1.020234272369 0.576427403421236 0.979182274965199 GO:0008157 protein phosphatase 1 binding 3/2108 26/18639 0.115384615384615 1.020234272369 0.576427403421236 0.979182274965199 GO:0008198 ferrous iron binding 3/2108 26/18639 0.115384615384615 1.020234272369 0.576427403421236 0.979182274965199 GO:0030507 spectrin binding 3/2108 26/18639 0.115384615384615 1.020234272369 0.576427403421236 0.979182274965199 GO:0070006 metalloaminopeptidase activity 3/2108 26/18639 0.115384615384615 1.020234272369 0.576427403421236 0.979182274965199 GO:0050661 NADP binding 6/2108 54/18639 0.111111111111111 0.982447817836812 0.582177559887533 0.979732563634314 GO:0046915 transition metal ion transmembrane transporter activity 5/2108 45/18639 0.111111111111111 0.982447817836812 0.586589799777932 0.979732563634314 GO:0051539 4 iron, 4 sulfur cluster binding 5/2108 45/18639 0.111111111111111 0.982447817836812 0.586589799777932 0.979732563634314 GO:0004550 nucleoside diphosphate kinase activity 2/2108 17/18639 0.117647058823529 1.04023886594486 0.588336024277025 0.979732563634314 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/2108 17/18639 0.117647058823529 1.04023886594486 0.588336024277025 0.979732563634314 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/2108 17/18639 0.117647058823529 1.04023886594486 0.588336024277025 0.979732563634314 GO:0016018 cyclosporin A binding 2/2108 17/18639 0.117647058823529 1.04023886594486 0.588336024277025 0.979732563634314 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/2108 17/18639 0.117647058823529 1.04023886594486 0.588336024277025 0.979732563634314 GO:0030548 acetylcholine receptor regulator activity 2/2108 17/18639 0.117647058823529 1.04023886594486 0.588336024277025 0.979732563634314 GO:0032183 SUMO binding 2/2108 17/18639 0.117647058823529 1.04023886594486 0.588336024277025 0.979732563634314 GO:0038191 neuropilin binding 2/2108 17/18639 0.117647058823529 1.04023886594486 0.588336024277025 0.979732563634314 GO:0046965 nuclear retinoid X receptor binding 2/2108 17/18639 0.117647058823529 1.04023886594486 0.588336024277025 0.979732563634314 GO:0070492 oligosaccharide binding 2/2108 17/18639 0.117647058823529 1.04023886594486 0.588336024277025 0.979732563634314 GO:1990226 histone methyltransferase binding 2/2108 17/18639 0.117647058823529 1.04023886594486 0.588336024277025 0.979732563634314 GO:0004386 helicase activity 17/2108 155/18639 0.109677419354839 0.969771071800208 0.591569411702704 0.983733403730339 GO:0004521 RNA endonuclease activity 8/2108 73/18639 0.10958904109589 0.968989628551376 0.592740663814775 0.984298661930847 GO:0004536 DNA nuclease activity 7/2108 64/18639 0.109375 0.967097070683112 0.596191396057203 0.988642315030433 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 3/2108 27/18639 0.111111111111111 0.982447817836812 0.602825546361274 0.998245380268179 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 25/2108 229/18639 0.109170305676856 0.965287157263243 0.606101771581025 1 GO:0023023 MHC protein complex binding 4/2108 37/18639 0.108108108108108 0.955895174111493 0.615228849309678 1 GO:0030280 structural constituent of skin epidermis 4/2108 37/18639 0.108108108108108 0.955895174111493 0.615228849309678 1 GO:0003746 translation elongation factor activity 2/2108 18/18639 0.111111111111111 0.982447817836812 0.620220231519292 1 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/2108 18/18639 0.111111111111111 0.982447817836812 0.620220231519292 1 GO:0008525 phosphatidylcholine transporter activity 2/2108 18/18639 0.111111111111111 0.982447817836812 0.620220231519292 1 GO:0017075 syntaxin-1 binding 2/2108 18/18639 0.111111111111111 0.982447817836812 0.620220231519292 1 GO:0031690 adrenergic receptor binding 2/2108 18/18639 0.111111111111111 0.982447817836812 0.620220231519292 1 GO:0032393 MHC class I receptor activity 2/2108 18/18639 0.111111111111111 0.982447817836812 0.620220231519292 1 GO:0035615 clathrin adaptor activity 2/2108 18/18639 0.111111111111111 0.982447817836812 0.620220231519292 1 GO:0099602 neurotransmitter receptor regulator activity 2/2108 18/18639 0.111111111111111 0.982447817836812 0.620220231519292 1 GO:1901611 phosphatidylglycerol binding 2/2108 18/18639 0.111111111111111 0.982447817836812 0.620220231519292 1 GO:0016866 intramolecular transferase activity 3/2108 28/18639 0.107142857142857 0.947360395771212 0.628111086719757 1 GO:0051959 dynein light intermediate chain binding 3/2108 28/18639 0.107142857142857 0.947360395771212 0.628111086719757 1 GO:0004601 peroxidase activity 6/2108 57/18639 0.105263157894737 0.930740037950664 0.636316006763472 1 GO:0005109 frizzled binding 4/2108 38/18639 0.105263157894737 0.930740037950664 0.636727966036157 1 GO:0008173 RNA methyltransferase activity 7/2108 67/18639 0.104477611940299 0.923794216771928 0.645566542816688 1 GO:0008301 DNA binding, bending 2/2108 19/18639 0.105263157894737 0.930740037950664 0.650161816405769 1 GO:0008381 mechanosensitive monoatomic ion channel activity 2/2108 19/18639 0.105263157894737 0.930740037950664 0.650161816405769 1 GO:0008574 plus-end-directed microtubule motor activity 2/2108 19/18639 0.105263157894737 0.930740037950664 0.650161816405769 1 GO:0030506 ankyrin binding 2/2108 19/18639 0.105263157894737 0.930740037950664 0.650161816405769 1 GO:0031420 alkali metal ion binding 2/2108 19/18639 0.105263157894737 0.930740037950664 0.650161816405769 1 GO:0016417 S-acyltransferase activity 3/2108 29/18639 0.103448275862069 0.914692795917032 0.652261749513058 1 GO:0035250 UDP-galactosyltransferase activity 3/2108 29/18639 0.103448275862069 0.914692795917032 0.652261749513058 1 GO:0022839 monoatomic ion-gated channel activity 3/2108 30/18639 0.1 0.884203036053131 0.675267290127821 1 GO:0048019 receptor antagonist activity 3/2108 30/18639 0.1 0.884203036053131 0.675267290127821 1 GO:0098918 structural constituent of synapse 3/2108 30/18639 0.1 0.884203036053131 0.675267290127821 1 GO:0004177 aminopeptidase activity 4/2108 40/18639 0.1 0.884203036053131 0.677319513618858 1 GO:0030331 nuclear estrogen receptor binding 4/2108 40/18639 0.1 0.884203036053131 0.677319513618858 1 GO:0071949 FAD binding 4/2108 40/18639 0.1 0.884203036053131 0.677319513618858 1 GO:0140662 ATP-dependent protein folding chaperone 4/2108 40/18639 0.1 0.884203036053131 0.677319513618858 1 GO:0000339 RNA cap binding 2/2108 20/18639 0.1 0.884203036053131 0.678192164071035 1 GO:0001614 purinergic nucleotide receptor activity 2/2108 20/18639 0.1 0.884203036053131 0.678192164071035 1 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/2108 20/18639 0.1 0.884203036053131 0.678192164071035 1 GO:0015095 magnesium ion transmembrane transporter activity 2/2108 20/18639 0.1 0.884203036053131 0.678192164071035 1 GO:0016502 nucleotide receptor activity 2/2108 20/18639 0.1 0.884203036053131 0.678192164071035 1 GO:0043024 ribosomal small subunit binding 2/2108 20/18639 0.1 0.884203036053131 0.678192164071035 1 GO:0052745 inositol phosphate phosphatase activity 2/2108 20/18639 0.1 0.884203036053131 0.678192164071035 1 GO:0004175 endopeptidase activity 43/2108 405/18639 0.106172839506173 0.938783470377398 0.694867202454778 1 GO:0001530 lipopolysaccharide binding 4/2108 41/18639 0.0975609756097561 0.862637108344518 0.696389643647147 1 GO:0008327 methyl-CpG binding 3/2108 31/18639 0.0967741935483871 0.855680357470772 0.697127878455246 1 GO:0016411 acylglycerol O-acyltransferase activity 3/2108 31/18639 0.0967741935483871 0.855680357470772 0.697127878455246 1 GO:0042277 peptide binding 26/2108 249/18639 0.104417670682731 0.923264214352667 0.697647598603505 1 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0004090 carbonyl reductase (NADPH) activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0004955 prostaglandin receptor activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0005131 growth hormone receptor binding 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0005381 iron ion transmembrane transporter activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0008401 retinoic acid 4-hydroxylase activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0015187 glycine transmembrane transporter activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0015643 toxic substance binding 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0016427 tRNA (cytidine) methyltransferase activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0016783 sulfurtransferase activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0031419 cobalamin binding 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0032356 oxidized DNA binding 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0033204 ribonuclease P RNA binding 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0035256 G protein-coupled glutamate receptor binding 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0035374 chondroitin sulfate binding 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0070739 protein-glutamic acid ligase activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0070740 tubulin-glutamic acid ligase activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0097177 mitochondrial ribosome binding 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0140940 histone H2A methyltransferase activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:1990259 histone H2AQ104 methyltransferase activity 1/2108 10/18639 0.1 0.884203036053131 0.698954997026542 1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 6/2108 61/18639 0.0983606557377049 0.869707904314555 0.701618498282077 1 GO:0001846 opsonin binding 2/2108 21/18639 0.0952380952380952 0.84209812957441 0.704360403701551 1 GO:0009975 cyclase activity 2/2108 21/18639 0.0952380952380952 0.84209812957441 0.704360403701551 1 GO:0010314 phosphatidylinositol-5-phosphate binding 2/2108 21/18639 0.0952380952380952 0.84209812957441 0.704360403701551 1 GO:0070182 DNA polymerase binding 2/2108 21/18639 0.0952380952380952 0.84209812957441 0.704360403701551 1 GO:0140312 cargo adaptor activity 2/2108 21/18639 0.0952380952380952 0.84209812957441 0.704360403701551 1 GO:1904047 S-adenosyl-L-methionine binding 2/2108 21/18639 0.0952380952380952 0.84209812957441 0.704360403701551 1 GO:0035198 miRNA binding 4/2108 42/18639 0.0952380952380952 0.84209812957441 0.714637575954739 1 GO:0051879 Hsp90 protein binding 4/2108 42/18639 0.0952380952380952 0.84209812957441 0.714637575954739 1 GO:0140767 enzyme-substrate adaptor activity 14/2108 139/18639 0.100719424460432 0.890564208974376 0.717092279049185 1 GO:0015106 bicarbonate transmembrane transporter activity 3/2108 32/18639 0.09375 0.82894034629981 0.717852601904174 1 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 13/2108 130/18639 0.1 0.884203036053131 0.722164828370865 1 GO:0005243 gap junction channel activity 2/2108 22/18639 0.0909090909090909 0.803820941866483 0.728728997074524 1 GO:0016881 acid-amino acid ligase activity 2/2108 22/18639 0.0909090909090909 0.803820941866483 0.728728997074524 1 GO:0034062 5'-3' RNA polymerase activity 2/2108 22/18639 0.0909090909090909 0.803820941866483 0.728728997074524 1 GO:0061133 endopeptidase activator activity 2/2108 22/18639 0.0909090909090909 0.803820941866483 0.728728997074524 1 GO:0097747 RNA polymerase activity 2/2108 22/18639 0.0909090909090909 0.803820941866483 0.728728997074524 1 GO:0008146 sulfotransferase activity 5/2108 53/18639 0.0943396226415094 0.834153807597293 0.730569740482484 1 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4/2108 43/18639 0.0930232558139535 0.822514452142447 0.73206587938535 1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0003953 NAD+ nucleosidase activity 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0004954 prostanoid receptor activity 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0005114 type II transforming growth factor beta receptor binding 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0005225 volume-sensitive anion channel activity 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0008199 ferric iron binding 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0008503 benzodiazepine receptor activity 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0015173 aromatic amino acid transmembrane transporter activity 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0032404 mismatch repair complex binding 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0034056 estrogen response element binding 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0047676 arachidonate-CoA ligase activity 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0097493 structural molecule activity conferring elasticity 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0180030 inositol phosphate kinase activity 1/2108 11/18639 0.0909090909090909 0.803820941866483 0.733020318099495 1 GO:0001540 amyloid-beta binding 8/2108 83/18639 0.0963855421686747 0.852243890171692 0.735340657312582 1 GO:0030296 protein tyrosine kinase activator activity 3/2108 33/18639 0.0909090909090909 0.803820941866483 0.737458091528751 1 GO:0017069 snRNA binding 5/2108 54/18639 0.0925925925925926 0.81870651486401 0.745711799726867 1 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 5/2108 54/18639 0.0925925925925926 0.81870651486401 0.745711799726867 1 GO:0051287 NAD binding 5/2108 54/18639 0.0925925925925926 0.81870651486401 0.745711799726867 1 GO:0016790 thiolester hydrolase activity 4/2108 44/18639 0.0909090909090909 0.803820941866483 0.74868153053027 1 GO:0016493 C-C chemokine receptor activity 2/2108 23/18639 0.0869565217391304 0.768872205263592 0.751370097231282 1 GO:0016849 phosphorus-oxygen lyase activity 2/2108 23/18639 0.0869565217391304 0.768872205263592 0.751370097231282 1 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 3/2108 34/18639 0.0882352941176471 0.780179149458645 0.755967271851677 1 GO:0019825 oxygen binding 3/2108 34/18639 0.0882352941176471 0.780179149458645 0.755967271851677 1 GO:0052866 phosphatidylinositol phosphate phosphatase activity 3/2108 34/18639 0.0882352941176471 0.780179149458645 0.755967271851677 1 GO:0044183 protein folding chaperone 7/2108 75/18639 0.0933333333333333 0.825256166982922 0.758393743859725 1 GO:0003774 cytoskeletal motor activity 15/2108 153/18639 0.0980392156862745 0.866865721620717 0.75887094736221 1 GO:0000340 RNA 7-methylguanosine cap binding 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0004032 aldose reductase (NADPH) activity 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0004526 ribonuclease P activity 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0005078 MAP-kinase scaffold activity 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0005165 neurotrophin receptor binding 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0005247 voltage-gated chloride channel activity 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0008603 cAMP-dependent protein kinase regulator activity 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0015132 prostaglandin transmembrane transporter activity 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0016208 AMP binding 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0016423 tRNA (guanine) methyltransferase activity 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0036009 protein-glutamine N-methyltransferase activity 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0042301 phosphate ion binding 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0070410 co-SMAD binding 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0097677 STAT family protein binding 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/2108 12/18639 0.0833333333333333 0.736835863377609 0.763232534625492 1 GO:0004896 cytokine receptor activity 9/2108 96/18639 0.09375 0.82894034629981 0.771567254034191 1 GO:0004622 lysophospholipase activity 2/2108 24/18639 0.0833333333333333 0.736835863377609 0.772362559635387 1 GO:0005540 hyaluronic acid binding 2/2108 24/18639 0.0833333333333333 0.736835863377609 0.772362559635387 1 GO:0019957 C-C chemokine binding 2/2108 24/18639 0.0833333333333333 0.736835863377609 0.772362559635387 1 GO:0030215 semaphorin receptor binding 2/2108 24/18639 0.0833333333333333 0.736835863377609 0.772362559635387 1 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/2108 24/18639 0.0833333333333333 0.736835863377609 0.772362559635387 1 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/2108 24/18639 0.0833333333333333 0.736835863377609 0.772362559635387 1 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/2108 24/18639 0.0833333333333333 0.736835863377609 0.772362559635387 1 GO:0050699 WW domain binding 2/2108 24/18639 0.0833333333333333 0.736835863377609 0.772362559635387 1 GO:0140612 DNA damage sensor activity 2/2108 24/18639 0.0833333333333333 0.736835863377609 0.772362559635387 1 GO:0008236 serine-type peptidase activity 19/2108 194/18639 0.0979381443298969 0.865972045619046 0.780244931831027 1 GO:0004519 endonuclease activity 12/2108 127/18639 0.094488188976378 0.835467435640754 0.785963620268975 1 GO:0004252 serine-type endopeptidase activity 17/2108 176/18639 0.0965909090909091 0.854059750733138 0.789361616707573 1 GO:0016409 palmitoyltransferase activity 3/2108 36/18639 0.0833333333333333 0.736835863377609 0.789813215461864 1 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/2108 13/18639 0.0769230769230769 0.680156181579332 0.790027285095748 1 GO:0008253 5'-nucleotidase activity 1/2108 13/18639 0.0769230769230769 0.680156181579332 0.790027285095748 1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/2108 13/18639 0.0769230769230769 0.680156181579332 0.790027285095748 1 GO:0031432 titin binding 1/2108 13/18639 0.0769230769230769 0.680156181579332 0.790027285095748 1 GO:0035325 Toll-like receptor binding 1/2108 13/18639 0.0769230769230769 0.680156181579332 0.790027285095748 1 GO:0035673 oligopeptide transmembrane transporter activity 1/2108 13/18639 0.0769230769230769 0.680156181579332 0.790027285095748 1 GO:0039706 co-receptor binding 1/2108 13/18639 0.0769230769230769 0.680156181579332 0.790027285095748 1 GO:0051011 microtubule minus-end binding 1/2108 13/18639 0.0769230769230769 0.680156181579332 0.790027285095748 1 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/2108 13/18639 0.0769230769230769 0.680156181579332 0.790027285095748 1 GO:0070700 BMP receptor binding 1/2108 13/18639 0.0769230769230769 0.680156181579332 0.790027285095748 1 GO:0071714 icosanoid transmembrane transporter activity 1/2108 13/18639 0.0769230769230769 0.680156181579332 0.790027285095748 1 GO:0071837 HMG box domain binding 1/2108 13/18639 0.0769230769230769 0.680156181579332 0.790027285095748 1 GO:1901338 catecholamine binding 1/2108 13/18639 0.0769230769230769 0.680156181579332 0.790027285095748 1 GO:0000030 mannosyltransferase activity 2/2108 25/18639 0.08 0.707362428842505 0.791789504908378 1 GO:0001848 complement binding 2/2108 25/18639 0.08 0.707362428842505 0.791789504908378 1 GO:0003707 nuclear steroid receptor activity 2/2108 25/18639 0.08 0.707362428842505 0.791789504908378 1 GO:0005537 D-mannose binding 2/2108 25/18639 0.08 0.707362428842505 0.791789504908378 1 GO:0008483 transaminase activity 2/2108 25/18639 0.08 0.707362428842505 0.791789504908378 1 GO:0015662 P-type ion transporter activity 2/2108 25/18639 0.08 0.707362428842505 0.791789504908378 1 GO:0047617 fatty acyl-CoA hydrolase activity 2/2108 25/18639 0.08 0.707362428842505 0.791789504908378 1 GO:0120020 cholesterol transfer activity 2/2108 25/18639 0.08 0.707362428842505 0.791789504908378 1 GO:0140358 P-type transmembrane transporter activity 2/2108 25/18639 0.08 0.707362428842505 0.791789504908378 1 GO:0030145 manganese ion binding 6/2108 68/18639 0.0882352941176471 0.780179149458645 0.795664707908328 1 GO:0030551 cyclic nucleotide binding 3/2108 37/18639 0.0810810810810811 0.71692138058362 0.805217718357645 1 GO:0042805 actinin binding 3/2108 37/18639 0.0810810810810811 0.71692138058362 0.805217718357645 1 GO:0043394 proteoglycan binding 3/2108 37/18639 0.0810810810810811 0.71692138058362 0.805217718357645 1 GO:0032266 phosphatidylinositol-3-phosphate binding 4/2108 48/18639 0.0833333333333333 0.736835863377609 0.807281227499316 1 GO:0017171 serine hydrolase activity 19/2108 198/18639 0.095959595959596 0.848477660859065 0.80844521524206 1 GO:0001637 G protein-coupled chemoattractant receptor activity 2/2108 26/18639 0.0769230769230769 0.680156181579332 0.809736346698973 1 GO:0004435 phosphatidylinositol phospholipase C activity 2/2108 26/18639 0.0769230769230769 0.680156181579332 0.809736346698973 1 GO:0004950 chemokine receptor activity 2/2108 26/18639 0.0769230769230769 0.680156181579332 0.809736346698973 1 GO:0005112 Notch binding 2/2108 26/18639 0.0769230769230769 0.680156181579332 0.809736346698973 1 GO:0016289 acyl-CoA hydrolase activity 2/2108 26/18639 0.0769230769230769 0.680156181579332 0.809736346698973 1 GO:0019865 immunoglobulin binding 2/2108 26/18639 0.0769230769230769 0.680156181579332 0.809736346698973 1 GO:0050750 low-density lipoprotein particle receptor binding 2/2108 26/18639 0.0769230769230769 0.680156181579332 0.809736346698973 1 GO:0097602 cullin family protein binding 2/2108 26/18639 0.0769230769230769 0.680156181579332 0.809736346698973 1 GO:0004879 nuclear receptor activity 5/2108 59/18639 0.0847457627118644 0.749324606824687 0.8120012032619 1 GO:0015459 potassium channel regulator activity 5/2108 59/18639 0.0847457627118644 0.749324606824687 0.8120012032619 1 GO:0004705 JUN kinase activity 1/2108 14/18639 0.0714285714285714 0.631573597180808 0.813790974724126 1 GO:0005545 1-phosphatidylinositol binding 1/2108 14/18639 0.0714285714285714 0.631573597180808 0.813790974724126 1 GO:0008174 mRNA methyltransferase activity 1/2108 14/18639 0.0714285714285714 0.631573597180808 0.813790974724126 1 GO:0008191 metalloendopeptidase inhibitor activity 1/2108 14/18639 0.0714285714285714 0.631573597180808 0.813790974724126 1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/2108 14/18639 0.0714285714285714 0.631573597180808 0.813790974724126 1 GO:0019763 immunoglobulin receptor activity 1/2108 14/18639 0.0714285714285714 0.631573597180808 0.813790974724126 1 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/2108 14/18639 0.0714285714285714 0.631573597180808 0.813790974724126 1 GO:1901474 azole transmembrane transporter activity 1/2108 14/18639 0.0714285714285714 0.631573597180808 0.813790974724126 1 GO:1901612 cardiolipin binding 1/2108 14/18639 0.0714285714285714 0.631573597180808 0.813790974724126 1 GO:1990825 sequence-specific mRNA binding 1/2108 14/18639 0.0714285714285714 0.631573597180808 0.813790974724126 1 GO:0000146 microfilament motor activity 3/2108 38/18639 0.0789473684210526 0.698055028462998 0.819659697128058 1 GO:0005501 retinoid binding 3/2108 38/18639 0.0789473684210526 0.698055028462998 0.819659697128058 1 GO:0019840 isoprenoid binding 3/2108 38/18639 0.0789473684210526 0.698055028462998 0.819659697128058 1 GO:0016763 pentosyltransferase activity 4/2108 49/18639 0.0816326530612245 0.721798396778066 0.820055522214068 1 GO:0035254 glutamate receptor binding 4/2108 49/18639 0.0816326530612245 0.721798396778066 0.820055522214068 1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 5/2108 60/18639 0.0833333333333333 0.736835863377609 0.823449681631716 1 GO:0098531 ligand-modulated transcription factor activity 5/2108 60/18639 0.0833333333333333 0.736835863377609 0.823449681631716 1 GO:0001618 virus receptor activity 7/2108 81/18639 0.0864197530864197 0.764126080539743 0.82423334596079 1 GO:0016405 CoA-ligase activity 2/2108 27/18639 0.0740740740740741 0.654965211891208 0.826289210725989 1 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 3/2108 39/18639 0.0769230769230769 0.680156181579332 0.833178870990091 1 GO:0140272 exogenous protein binding 7/2108 82/18639 0.0853658536585366 0.754807469801453 0.833702093516302 1 GO:0015026 coreceptor activity 5/2108 61/18639 0.0819672131147541 0.724756586928796 0.834327465859362 1 GO:0016836 hydro-lyase activity 5/2108 61/18639 0.0819672131147541 0.724756586928796 0.834327465859362 1 GO:0004089 carbonate dehydratase activity 1/2108 15/18639 0.0666666666666667 0.589468690702087 0.834866337155349 1 GO:0004467 long-chain fatty acid-CoA ligase activity 1/2108 15/18639 0.0666666666666667 0.589468690702087 0.834866337155349 1 GO:0004559 alpha-mannosidase activity 1/2108 15/18639 0.0666666666666667 0.589468690702087 0.834866337155349 1 GO:0004953 icosanoid receptor activity 1/2108 15/18639 0.0666666666666667 0.589468690702087 0.834866337155349 1 GO:0005041 low-density lipoprotein particle receptor activity 1/2108 15/18639 0.0666666666666667 0.589468690702087 0.834866337155349 1 GO:0008252 nucleotidase activity 1/2108 15/18639 0.0666666666666667 0.589468690702087 0.834866337155349 1 GO:0015929 hexosaminidase activity 1/2108 15/18639 0.0666666666666667 0.589468690702087 0.834866337155349 1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/2108 15/18639 0.0666666666666667 0.589468690702087 0.834866337155349 1 GO:0016846 carbon-sulfur lyase activity 1/2108 15/18639 0.0666666666666667 0.589468690702087 0.834866337155349 1 GO:0034483 heparan sulfate sulfotransferase activity 1/2108 15/18639 0.0666666666666667 0.589468690702087 0.834866337155349 1 GO:0045504 dynein heavy chain binding 1/2108 15/18639 0.0666666666666667 0.589468690702087 0.834866337155349 1 GO:0050780 dopamine receptor binding 1/2108 15/18639 0.0666666666666667 0.589468690702087 0.834866337155349 1 GO:0120283 protein serine/threonine kinase binding 1/2108 15/18639 0.0666666666666667 0.589468690702087 0.834866337155349 1 GO:0141050 histone H3K deacetylase activity 1/2108 15/18639 0.0666666666666667 0.589468690702087 0.834866337155349 1 GO:0141051 histone H4K deacetylase activity 1/2108 15/18639 0.0666666666666667 0.589468690702087 0.834866337155349 1 GO:0042379 chemokine receptor binding 6/2108 72/18639 0.0833333333333333 0.736835863377609 0.838137372807736 1 GO:0045499 chemorepellent activity 2/2108 28/18639 0.0714285714285714 0.631573597180808 0.841533681803391 1 GO:0051393 alpha-actinin binding 2/2108 28/18639 0.0714285714285714 0.631573597180808 0.841533681803391 1 GO:0019955 cytokine binding 13/2108 144/18639 0.0902777777777778 0.79823885199241 0.841742153684963 1 GO:0042562 hormone binding 8/2108 94/18639 0.0851063829787234 0.752513222172877 0.847784265526522 1 GO:0003688 DNA replication origin binding 1/2108 16/18639 0.0625 0.552626897533207 0.853557368151726 1 GO:0004707 MAP kinase activity 1/2108 16/18639 0.0625 0.552626897533207 0.853557368151726 1 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/2108 16/18639 0.0625 0.552626897533207 0.853557368151726 1 GO:0015923 mannosidase activity 1/2108 16/18639 0.0625 0.552626897533207 0.853557368151726 1 GO:0019841 retinol binding 1/2108 16/18639 0.0625 0.552626897533207 0.853557368151726 1 GO:0022858 alanine transmembrane transporter activity 1/2108 16/18639 0.0625 0.552626897533207 0.853557368151726 1 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/2108 16/18639 0.0625 0.552626897533207 0.853557368151726 1 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/2108 16/18639 0.0625 0.552626897533207 0.853557368151726 1 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/2108 16/18639 0.0625 0.552626897533207 0.853557368151726 1 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/2108 16/18639 0.0625 0.552626897533207 0.853557368151726 1 GO:0004181 metallocarboxypeptidase activity 2/2108 29/18639 0.0689655172413793 0.609795197278021 0.855553824936009 1 GO:0004629 phospholipase C activity 2/2108 29/18639 0.0689655172413793 0.609795197278021 0.855553824936009 1 GO:0042287 MHC protein binding 3/2108 41/18639 0.0731707317073171 0.646977831258388 0.857612942961448 1 GO:1901681 sulfur compound binding 26/2108 275/18639 0.0945454545454545 0.835973779541142 0.859806266209702 1 GO:0016860 intramolecular oxidoreductase activity 4/2108 53/18639 0.0754716981132075 0.667323046077835 0.864329395005345 1 GO:0033218 amide binding 23/2108 247/18639 0.0931174089068826 0.823346956648665 0.865644720634117 1 GO:0050660 flavin adenine dinucleotide binding 7/2108 86/18639 0.0813953488372093 0.719700145624641 0.867582049266734 1 GO:0008106 alcohol dehydrogenase (NADP+) activity 2/2108 30/18639 0.0666666666666667 0.589468690702087 0.868431434565165 1 GO:0004520 DNA endonuclease activity 3/2108 42/18639 0.0714285714285714 0.631573597180808 0.86861104811581 1 GO:0008307 structural constituent of muscle 3/2108 42/18639 0.0714285714285714 0.631573597180808 0.86861104811581 1 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/2108 17/18639 0.0588235294117647 0.52011943297243 0.870133702143895 1 GO:0004549 tRNA-specific ribonuclease activity 1/2108 17/18639 0.0588235294117647 0.52011943297243 0.870133702143895 1 GO:0004659 prenyltransferase activity 1/2108 17/18639 0.0588235294117647 0.52011943297243 0.870133702143895 1 GO:0009881 photoreceptor activity 1/2108 17/18639 0.0588235294117647 0.52011943297243 0.870133702143895 1 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/2108 17/18639 0.0588235294117647 0.52011943297243 0.870133702143895 1 GO:0017110 nucleoside diphosphate phosphatase activity 1/2108 17/18639 0.0588235294117647 0.52011943297243 0.870133702143895 1 GO:0030169 low-density lipoprotein particle binding 1/2108 17/18639 0.0588235294117647 0.52011943297243 0.870133702143895 1 GO:0036041 long-chain fatty acid binding 1/2108 17/18639 0.0588235294117647 0.52011943297243 0.870133702143895 1 GO:0045125 bioactive lipid receptor activity 1/2108 17/18639 0.0588235294117647 0.52011943297243 0.870133702143895 1 GO:0070403 NAD+ binding 1/2108 17/18639 0.0588235294117647 0.52011943297243 0.870133702143895 1 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/2108 31/18639 0.0645161290322581 0.570453571647181 0.880245472917573 1 GO:0070325 lipoprotein particle receptor binding 2/2108 31/18639 0.0645161290322581 0.570453571647181 0.880245472917573 1 GO:0008235 metalloexopeptidase activity 5/2108 66/18639 0.0757575757575758 0.669850784888736 0.880751250535332 1 GO:0003724 RNA helicase activity 6/2108 77/18639 0.0779220779220779 0.688989378742699 0.880876437927715 1 GO:0008374 O-acyltransferase activity 4/2108 55/18639 0.0727272727272727 0.643056753493186 0.882728925232538 1 GO:0015172 acidic amino acid transmembrane transporter activity 1/2108 18/18639 0.0555555555555556 0.491223908918406 0.884834494533578 1 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/2108 18/18639 0.0555555555555556 0.491223908918406 0.884834494533578 1 GO:0022851 GABA-gated chloride ion channel activity 1/2108 18/18639 0.0555555555555556 0.491223908918406 0.884834494533578 1 GO:0030228 lipoprotein particle receptor activity 1/2108 18/18639 0.0555555555555556 0.491223908918406 0.884834494533578 1 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/2108 18/18639 0.0555555555555556 0.491223908918406 0.884834494533578 1 GO:0001223 transcription coactivator binding 3/2108 44/18639 0.0681818181818182 0.602865706399862 0.888376599568667 1 GO:0030020 extracellular matrix structural constituent conferring tensile strength 3/2108 44/18639 0.0681818181818182 0.602865706399862 0.888376599568667 1 GO:0043425 bHLH transcription factor binding 2/2108 32/18639 0.0625 0.552626897533207 0.891071664318466 1 GO:0008186 ATP-dependent activity, acting on RNA 6/2108 79/18639 0.0759493670886076 0.671546609660606 0.895091179579225 1 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 10/2108 122/18639 0.0819672131147541 0.724756586928796 0.895675057363515 1 GO:0003756 protein disulfide isomerase activity 1/2108 19/18639 0.0526315789473684 0.465370018975332 0.897871865540678 1 GO:0004890 GABA-A receptor activity 1/2108 19/18639 0.0526315789473684 0.465370018975332 0.897871865540678 1 GO:0005229 intracellularly calcium-gated chloride channel activity 1/2108 19/18639 0.0526315789473684 0.465370018975332 0.897871865540678 1 GO:0015245 fatty acid transmembrane transporter activity 1/2108 19/18639 0.0526315789473684 0.465370018975332 0.897871865540678 1 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/2108 19/18639 0.0526315789473684 0.465370018975332 0.897871865540678 1 GO:0016918 retinal binding 1/2108 19/18639 0.0526315789473684 0.465370018975332 0.897871865540678 1 GO:0043395 heparan sulfate proteoglycan binding 1/2108 19/18639 0.0526315789473684 0.465370018975332 0.897871865540678 1 GO:0046624 sphingolipid transporter activity 1/2108 19/18639 0.0526315789473684 0.465370018975332 0.897871865540678 1 GO:0141147 intracellularly calcium-gated channel activity 1/2108 19/18639 0.0526315789473684 0.465370018975332 0.897871865540678 1 GO:0019239 deaminase activity 2/2108 33/18639 0.0606060606060606 0.535880627910988 0.900982217401674 1 GO:0004180 carboxypeptidase activity 3/2108 46/18639 0.0652173913043478 0.576654153947694 0.905437148556055 1 GO:0008194 UDP-glycosyltransferase activity 12/2108 145/18639 0.0827586206896552 0.731754236733625 0.906172194390213 1 GO:0140375 immune receptor activity 13/2108 156/18639 0.0833333333333333 0.736835863377609 0.908889273664089 1 GO:0016408 C-acyltransferase activity 1/2108 20/18639 0.05 0.442101518026565 0.909433955091712 1 GO:0031418 L-ascorbic acid binding 1/2108 20/18639 0.05 0.442101518026565 0.909433955091712 1 GO:0042288 MHC class I protein binding 1/2108 20/18639 0.05 0.442101518026565 0.909433955091712 1 GO:0140664 ATP-dependent DNA damage sensor activity 1/2108 20/18639 0.05 0.442101518026565 0.909433955091712 1 GO:0008175 tRNA methyltransferase activity 2/2108 34/18639 0.0588235294117647 0.52011943297243 0.910045651498548 1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/2108 34/18639 0.0588235294117647 0.52011943297243 0.910045651498548 1 GO:0051427 hormone receptor binding 2/2108 34/18639 0.0588235294117647 0.52011943297243 0.910045651498548 1 GO:0005504 fatty acid binding 3/2108 47/18639 0.0638297872340425 0.564384916629658 0.913050339602331 1 GO:0043015 gamma-tubulin binding 2/2108 35/18639 0.0571428571428571 0.505258877744646 0.918326707212779 1 GO:0015174 basic amino acid transmembrane transporter activity 1/2108 21/18639 0.0476190476190476 0.421049064787205 0.91968763266122 1 GO:0051428 peptide hormone receptor binding 1/2108 21/18639 0.0476190476190476 0.421049064787205 0.91968763266122 1 GO:0061891 calcium ion sensor activity 1/2108 21/18639 0.0476190476190476 0.421049064787205 0.91968763266122 1 GO:0016879 ligase activity, forming carbon-nitrogen bonds 3/2108 48/18639 0.0625 0.552626897533207 0.920101613742532 1 GO:0005518 collagen binding 5/2108 72/18639 0.0694444444444444 0.614029886148008 0.921359370946738 1 GO:0016853 isomerase activity 15/2108 180/18639 0.0833333333333333 0.736835863377609 0.922024770428392 1 GO:0004033 aldo-keto reductase (NADPH) activity 2/2108 36/18639 0.0555555555555556 0.491223908918406 0.925886324374597 1 GO:0004190 aspartic-type endopeptidase activity 2/2108 36/18639 0.0555555555555556 0.491223908918406 0.925886324374597 1 GO:0004407 histone deacetylase activity 1/2108 22/18639 0.0454545454545455 0.401910470933241 0.928780901022491 1 GO:0015377 chloride:monoatomic cation symporter activity 1/2108 22/18639 0.0454545454545455 0.401910470933241 0.928780901022491 1 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/2108 22/18639 0.0454545454545455 0.401910470933241 0.928780901022491 1 GO:0033558 protein lysine deacetylase activity 1/2108 22/18639 0.0454545454545455 0.401910470933241 0.928780901022491 1 GO:0033691 sialic acid binding 1/2108 22/18639 0.0454545454545455 0.401910470933241 0.928780901022491 1 GO:0140784 metal ion sensor activity 1/2108 22/18639 0.0454545454545455 0.401910470933241 0.928780901022491 1 GO:0015179 L-amino acid transmembrane transporter activity 4/2108 62/18639 0.0645161290322581 0.570453571647181 0.931055851415664 1 GO:0048020 CCR chemokine receptor binding 3/2108 50/18639 0.06 0.530521821631879 0.932658497747191 1 GO:0019213 deacetylase activity 2/2108 37/18639 0.0540540540540541 0.477947587055746 0.932781673289852 1 GO:0070001 aspartic-type peptidase activity 2/2108 37/18639 0.0540540540540541 0.477947587055746 0.932781673289852 1 GO:0046906 tetrapyrrole binding 12/2108 152/18639 0.0789473684210526 0.698055028462998 0.934462283811135 1 GO:0008237 metallopeptidase activity 15/2108 184/18639 0.0815217391304348 0.720817692434618 0.935571020682961 1 GO:0042626 ATPase-coupled transmembrane transporter activity 7/2108 98/18639 0.0714285714285714 0.631573597180808 0.936736789724165 1 GO:0005212 structural constituent of eye lens 1/2108 23/18639 0.0434782608695652 0.384436102631796 0.936845028467546 1 GO:0005283 amino acid:sodium symporter activity 1/2108 23/18639 0.0434782608695652 0.384436102631796 0.936845028467546 1 GO:0016917 GABA receptor activity 1/2108 23/18639 0.0434782608695652 0.384436102631796 0.936845028467546 1 GO:0031681 G-protein beta-subunit binding 1/2108 23/18639 0.0434782608695652 0.384436102631796 0.936845028467546 1 GO:0020037 heme binding 11/2108 142/18639 0.0774647887323944 0.684946013843975 0.936904390675978 1 GO:0005010 insulin-like growth factor receptor activity 3/2108 51/18639 0.0588235294117647 0.52011943297243 0.938230440927613 1 GO:0005506 iron ion binding 12/2108 154/18639 0.0779220779220779 0.688989378742699 0.941060479760746 1 GO:0016758 hexosyltransferase activity 16/2108 197/18639 0.0812182741116751 0.718134445525385 0.942973908125479 1 GO:0015295 solute:proton symporter activity 1/2108 24/18639 0.0416666666666667 0.368417931688805 0.943996440155901 1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/2108 24/18639 0.0416666666666667 0.368417931688805 0.943996440155901 1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/2108 24/18639 0.0416666666666667 0.368417931688805 0.943996440155901 1 GO:0030246 carbohydrate binding 24/2108 280/18639 0.0857142857142857 0.757888316616969 0.944332465709266 1 GO:0160215 deacylase activity 4/2108 65/18639 0.0615384615384615 0.544124945263465 0.945586358793475 1 GO:0017046 peptide hormone binding 3/2108 53/18639 0.0566037735849057 0.500492284558376 0.948115680073118 1 GO:0019199 transmembrane receptor protein kinase activity 5/2108 78/18639 0.0641025641025641 0.566796817982776 0.94921341610711 1 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/2108 40/18639 0.05 0.442101518026565 0.949999013268959 1 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/2108 25/18639 0.04 0.353681214421252 0.950338395791215 1 GO:0015645 fatty acid ligase activity 1/2108 25/18639 0.04 0.353681214421252 0.950338395791215 1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/2108 25/18639 0.04 0.353681214421252 0.950338395791215 1 GO:0120515 fatty acid-CoA ligase activity 1/2108 25/18639 0.04 0.353681214421252 0.950338395791215 1 GO:0008238 exopeptidase activity 7/2108 102/18639 0.0686274509803922 0.606806005134502 0.951353490564381 1 GO:0015085 calcium ion transmembrane transporter activity 11/2108 147/18639 0.0748299319727891 0.661648530379894 0.952250806163117 1 GO:0033293 monocarboxylic acid binding 5/2108 79/18639 0.0632911392405063 0.559622174717172 0.952870323980616 1 GO:0005253 monoatomic anion channel activity 7/2108 103/18639 0.0679611650485437 0.600914684696303 0.954499534850723 1 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/2108 41/18639 0.0487804878048781 0.431318554172259 0.954736760464216 1 GO:0005126 cytokine receptor binding 23/2108 275/18639 0.0836363636363636 0.739515266517164 0.955326812484851 1 GO:0030247 polysaccharide binding 1/2108 26/18639 0.0384615384615385 0.340078090789666 0.955962477754904 1 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 14/2108 181/18639 0.0773480662983425 0.683913950538333 0.956053554528971 1 GO:0003777 microtubule motor activity 4/2108 68/18639 0.0588235294117647 0.52011943297243 0.957261932734 1 GO:0005104 fibroblast growth factor receptor binding 1/2108 27/18639 0.037037037037037 0.327482605945604 0.96094991110217 1 GO:0008395 steroid hydroxylase activity 1/2108 27/18639 0.037037037037037 0.327482605945604 0.96094991110217 1 GO:0023026 MHC class II protein complex binding 1/2108 27/18639 0.037037037037037 0.327482605945604 0.96094991110217 1 GO:0035255 ionotropic glutamate receptor binding 1/2108 27/18639 0.037037037037037 0.327482605945604 0.96094991110217 1 GO:0015932 nucleobase-containing compound transmembrane transporter activity 3/2108 57/18639 0.0526315789473684 0.465370018975332 0.963619204272551 1 GO:0005262 calcium channel activity 9/2108 131/18639 0.0687022900763359 0.607467734692991 0.967317432684884 1 GO:0005416 amino acid:monoatomic cation symporter activity 1/2108 29/18639 0.0344827586206897 0.304897598639011 0.969294838319301 1 GO:0036002 pre-mRNA binding 3/2108 59/18639 0.0508474576271186 0.449594764094812 0.969622651860717 1 GO:0008009 chemokine activity 2/2108 45/18639 0.0444444444444444 0.392979127134725 0.96972851782636 1 GO:0004620 phospholipase activity 7/2108 109/18639 0.0642201834862385 0.567836812144213 0.969818247861261 1 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/2108 60/18639 0.05 0.442101518026565 0.972260473958886 1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/2108 46/18639 0.0434782608695652 0.384436102631796 0.972650852793192 1 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/2108 46/18639 0.0434782608695652 0.384436102631796 0.972650852793192 1 GO:0015215 nucleotide transmembrane transporter activity 1/2108 30/18639 0.0333333333333333 0.294734345351044 0.972772886724616 1 GO:0033612 receptor serine/threonine kinase binding 1/2108 30/18639 0.0333333333333333 0.294734345351044 0.972772886724616 1 GO:0048029 monosaccharide binding 4/2108 74/18639 0.0540540540540541 0.477947587055746 0.973980426860478 1 GO:0099095 ligand-gated monoatomic anion channel activity 2/2108 47/18639 0.0425531914893617 0.376256611086439 0.975299764490564 1 GO:0005452 solute:inorganic anion antiporter activity 1/2108 31/18639 0.032258064516129 0.285226785823591 0.975857133851518 1 GO:0017147 Wnt-protein binding 1/2108 31/18639 0.032258064516129 0.285226785823591 0.975857133851518 1 GO:0042910 xenobiotic transmembrane transporter activity 1/2108 32/18639 0.03125 0.276313448766603 0.978592148997745 1 GO:0071813 lipoprotein particle binding 1/2108 32/18639 0.03125 0.276313448766603 0.978592148997745 1 GO:0071814 protein-lipid complex binding 1/2108 32/18639 0.03125 0.276313448766603 0.978592148997745 1 GO:0008201 heparin binding 12/2108 172/18639 0.0697674418604651 0.616885839106835 0.978765674637424 1 GO:0005004 GPI-linked ephrin receptor activity 2/2108 49/18639 0.0408163265306122 0.360899198389033 0.9798730170775 1 GO:0005008 hepatocyte growth factor receptor activity 2/2108 49/18639 0.0408163265306122 0.360899198389033 0.9798730170775 1 GO:0005009 insulin receptor activity 2/2108 49/18639 0.0408163265306122 0.360899198389033 0.9798730170775 1 GO:0005011 macrophage colony-stimulating factor receptor activity 2/2108 49/18639 0.0408163265306122 0.360899198389033 0.9798730170775 1 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/2108 49/18639 0.0408163265306122 0.360899198389033 0.9798730170775 1 GO:0005020 stem cell factor receptor activity 2/2108 49/18639 0.0408163265306122 0.360899198389033 0.9798730170775 1 GO:0008288 boss receptor activity 2/2108 49/18639 0.0408163265306122 0.360899198389033 0.9798730170775 1 GO:0036332 placental growth factor receptor activity 2/2108 49/18639 0.0408163265306122 0.360899198389033 0.9798730170775 1 GO:0038062 protein tyrosine kinase collagen receptor activity 2/2108 49/18639 0.0408163265306122 0.360899198389033 0.9798730170775 1 GO:0060175 brain-derived neurotrophic factor receptor activity 2/2108 49/18639 0.0408163265306122 0.360899198389033 0.9798730170775 1 GO:0042923 neuropeptide binding 1/2108 33/18639 0.0303030303030303 0.267940313955494 0.981017459360122 1 GO:0005006 epidermal growth factor receptor activity 2/2108 50/18639 0.04 0.353681214421252 0.981840288716262 1 GO:0005007 fibroblast growth factor receptor activity 2/2108 50/18639 0.04 0.353681214421252 0.981840288716262 1 GO:0005017 platelet-derived growth factor receptor activity 2/2108 50/18639 0.04 0.353681214421252 0.981840288716262 1 GO:0005019 platelet-derived growth factor beta-receptor activity 2/2108 50/18639 0.04 0.353681214421252 0.981840288716262 1 GO:0015605 organophosphate ester transmembrane transporter activity 2/2108 50/18639 0.04 0.353681214421252 0.981840288716262 1 GO:0052689 carboxylic ester hydrolase activity 5/2108 92/18639 0.0543478260869565 0.480545128289745 0.982896945485707 1 GO:0015020 glucuronosyltransferase activity 1/2108 34/18639 0.0294117647058824 0.260059716486215 0.983168120204412 1 GO:0005021 vascular endothelial growth factor receptor activity 2/2108 51/18639 0.0392156862745098 0.346746288648287 0.983620282503554 1 GO:0005030 neurotrophin receptor activity 2/2108 51/18639 0.0392156862745098 0.346746288648287 0.983620282503554 1 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 41/2108 484/18639 0.0847107438016529 0.749014968557404 0.983741993171673 1 GO:0004497 monooxygenase activity 6/2108 106/18639 0.0566037735849057 0.500492284558376 0.98458679526664 1 GO:0005343 organic acid:sodium symporter activity 1/2108 35/18639 0.0285714285714286 0.252629438872323 0.985075220586519 1 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 2/2108 52/18639 0.0384615384615385 0.340078090789666 0.985230171397151 1 GO:0016757 glycosyltransferase activity 20/2108 267/18639 0.0749063670411985 0.662324371575379 0.985420342855789 1 GO:0016500 protein-hormone receptor activity 3/2108 67/18639 0.0447761194029851 0.395911807187969 0.98547865064546 1 GO:0015101 organic cation transmembrane transporter activity 4/2108 81/18639 0.0493827160493827 0.436643474594139 0.985700453018348 1 GO:0005003 ephrin receptor activity 2/2108 53/18639 0.0377358490566038 0.333661523038917 0.986685641645153 1 GO:0005005 transmembrane-ephrin receptor activity 2/2108 53/18639 0.0377358490566038 0.333661523038917 0.986685641645153 1 GO:0038064 collagen receptor activity 2/2108 53/18639 0.0377358490566038 0.333661523038917 0.986685641645153 1 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/2108 53/18639 0.0377358490566038 0.333661523038917 0.986685641645153 1 GO:0001216 DNA-binding transcription activator activity 41/2108 491/18639 0.0835030549898167 0.738336547417075 0.987659329244215 1 GO:0005254 chloride channel activity 4/2108 83/18639 0.0481927710843374 0.426121945085846 0.98799035730166 1 GO:0004222 metalloendopeptidase activity 6/2108 110/18639 0.0545454545454545 0.48229256511989 0.988702170805721 1 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/2108 70/18639 0.0428571428571429 0.378944158308485 0.989056962609756 1 GO:0042887 amide transmembrane transporter activity 1/2108 38/18639 0.0263157894736842 0.232685009487666 0.989595626790745 1 GO:0140299 molecular sensor activity 3/2108 71/18639 0.0422535211267606 0.373606916642168 0.990048461609981 1 GO:0008509 monoatomic anion transmembrane transporter activity 9/2108 149/18639 0.0604026845637584 0.534082370770348 0.990177657703648 1 GO:0170055 lipid transmembrane transporter activity 2/2108 56/18639 0.0357142857142857 0.315786798590404 0.990262496537909 1 GO:0005539 glycosaminoglycan binding 17/2108 242/18639 0.0702479338842975 0.621134364169555 0.990538010455198 1 GO:0008083 growth factor activity 10/2108 162/18639 0.0617283950617284 0.545804343242673 0.990833103323583 1 GO:0022804 active transmembrane transporter activity 37/2108 457/18639 0.0809628008752735 0.715875543412819 0.990868311956549 1 GO:0070888 E-box binding 2/2108 59/18639 0.0338983050847458 0.299729842729875 0.992894605604292 1 GO:0015294 solute:monoatomic cation symporter activity 6/2108 116/18639 0.0517241379310345 0.457346397958516 0.992983484259598 1 GO:0016298 lipase activity 7/2108 130/18639 0.0538461538461538 0.476109327105532 0.993574165833905 1 GO:0005245 voltage-gated calcium channel activity 1/2108 43/18639 0.0232558139534884 0.205628613035612 0.994298319116057 1 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 6/2108 122/18639 0.0491803278688525 0.434853952157278 0.995692413417402 1 GO:0031406 carboxylic acid binding 11/2108 187/18639 0.0588235294117647 0.52011943297243 0.996233347895468 1 GO:0140359 ABC-type transporter activity 1/2108 47/18639 0.0212765957446809 0.188128305543219 0.996476463665311 1 GO:0043177 organic acid binding 11/2108 189/18639 0.0582010582010582 0.514615523628806 0.9967234316404 1 GO:0008188 neuropeptide receptor activity 1/2108 48/18639 0.0208333333333333 0.184208965844402 0.996875969613757 1 GO:0038187 pattern recognition receptor activity 1/2108 48/18639 0.0208333333333333 0.184208965844402 0.996875969613757 1 GO:0001664 G protein-coupled receptor binding 20/2108 297/18639 0.0673400673400673 0.595422919901098 0.997200356510959 1 GO:0005201 extracellular matrix structural constituent 9/2108 168/18639 0.0535714285714286 0.473680197885606 0.997529510742798 1 GO:0015171 amino acid transmembrane transporter activity 4/2108 102/18639 0.0392156862745098 0.346746288648287 0.997853974490605 1 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 6/2108 132/18639 0.0454545454545455 0.401910470933241 0.998133373890511 1 GO:0015293 symporter activity 7/2108 146/18639 0.0479452054794521 0.423932962491227 0.998201081561328 1 GO:0015108 chloride transmembrane transporter activity 5/2108 121/18639 0.0413223140495868 0.365373155393856 0.998568399297148 1 GO:0015370 solute:sodium symporter activity 2/2108 79/18639 0.0253164556962025 0.223848869886869 0.999169702843046 1 GO:0016798 hydrolase activity, acting on glycosyl bonds 5/2108 130/18639 0.0384615384615385 0.340078090789666 0.999367076420876 1 GO:0003730 mRNA 3'-UTR binding 15/2108 262/18639 0.0572519083969466 0.506223112244159 0.999383393728568 1 GO:0046943 carboxylic acid transmembrane transporter activity 9/2108 188/18639 0.0478723404255319 0.423288687472244 0.999477460875454 1 GO:0022824 transmitter-gated monoatomic ion channel activity 1/2108 63/18639 0.0158730158730159 0.140349688262402 0.999486661308925 1 GO:0022835 transmitter-gated channel activity 1/2108 63/18639 0.0158730158730159 0.140349688262402 0.999486661308925 1 GO:0005342 organic acid transmembrane transporter activity 9/2108 189/18639 0.0476190476190476 0.421049064787205 0.999517653122983 1 GO:0038024 cargo receptor activity 1/2108 65/18639 0.0153846153846154 0.136031236315866 0.999596560591983 1 GO:0008528 G protein-coupled peptide receptor activity 4/2108 122/18639 0.0327868852459016 0.289902634771518 0.999682632758906 1 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/2108 91/18639 0.021978021978022 0.194330337594095 0.99977754081545 1 GO:0001653 peptide receptor activity 4/2108 128/18639 0.03125 0.276313448766603 0.999823856159547 1 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/2108 73/18639 0.0136986301369863 0.121123703568922 0.999846129332338 1 GO:0005179 hormone activity 4/2108 132/18639 0.0303030303030303 0.267940313955494 0.99988144186913 1 GO:0030594 neurotransmitter receptor activity 2/2108 97/18639 0.0206185567010309 0.182309904340852 0.999885558146409 1 GO:0005125 cytokine activity 11/2108 234/18639 0.047008547008547 0.415650999854036 0.999888020505755 1 GO:0005249 voltage-gated potassium channel activity 2/2108 98/18639 0.0204081632653061 0.180449599194517 0.999897595134794 1 GO:0015103 inorganic anion transmembrane transporter activity 6/2108 165/18639 0.0363636363636364 0.321528376746593 0.999899905449835 1 GO:0019842 vitamin binding 5/2108 150/18639 0.0333333333333333 0.294734345351044 0.999902755119856 1 GO:0015297 antiporter activity 4/2108 135/18639 0.0296296296296296 0.261986084756483 0.999912046983015 1 GO:0005261 monoatomic cation channel activity 19/2108 341/18639 0.0557184750733138 0.492664448240747 0.999921410816005 1 GO:0008514 organic anion transmembrane transporter activity 13/2108 269/18639 0.0483271375464684 0.427310017423446 0.999942479721776 1 GO:0005244 voltage-gated monoatomic ion channel activity 6/2108 173/18639 0.0346820809248555 0.306660012503976 0.999952270101571 1 GO:0005267 potassium channel activity 3/2108 124/18639 0.0241935483870968 0.213920089367693 0.999953392884043 1 GO:0005216 monoatomic ion channel activity 27/2108 448/18639 0.0602678571428571 0.532890222621307 0.999960360304768 1 GO:0022832 voltage-gated channel activity 6/2108 175/18639 0.0342857142857143 0.303155326646788 0.999960401169599 1 GO:0099094 ligand-gated monoatomic cation channel activity 3/2108 136/18639 0.0220588235294118 0.195044787364661 0.99998697993856 1 GO:0003823 antigen binding 5/2108 174/18639 0.028735632183908 0.254081332199176 0.99999058306334 1 GO:0015079 potassium ion transmembrane transporter activity 4/2108 160/18639 0.025 0.221050759013283 0.999993044343675 1 GO:0022843 voltage-gated monoatomic cation channel activity 3/2108 143/18639 0.020979020979021 0.185497140430727 0.999993855517162 1 GO:0022834 ligand-gated channel activity 5/2108 188/18639 0.0265957446808511 0.235160381929024 0.9999976712318 1 GO:0015291 secondary active transmembrane transporter activity 11/2108 287/18639 0.0383275261324042 0.338893149706775 0.999998668764244 1 GO:0015276 ligand-gated monoatomic ion channel activity 4/2108 186/18639 0.021505376344086 0.19015119054906 0.999999539131045 1 GO:0046873 metal ion transmembrane transporter activity 22/2108 450/18639 0.0488888888888889 0.432277039848197 0.999999543536208 1 GO:0022836 gated channel activity 11/2108 318/18639 0.0345911949685535 0.305856396119008 0.999999915796058 1 GO:0015081 sodium ion transmembrane transporter activity 2/2108 164/18639 0.0121951219512195 0.107829638543065 0.999999942905296 1 GO:0045182 translation regulator activity 9/2108 356/18639 0.0252808988764045 0.22353447540669 0.999999999895086 1 GO:0030371 translation repressor activity 1/2108 329/18639 0.00303951367781155 0.0268754722204599 1 1