category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Genetic Information Processing	Translation	hsa03010	Ribosome	55/108	222/9376	21.5081748415082	RPS27/RPL10/RPS4X/RPL37/RPL30/RPL39/RPS12/RPL12/RPL34/RPL41/RPL28/RPS8/RPL13/RPS28/RPS27A/RPS6/RPS13/RPL37A/RPL32/RPS21/RPS3A/RPS3/RPLP1/RPL19/RPS14/RPS24/RPL14/RPLP2/RPL6/RPS23/RPL35/RPS29/UBA52/RPL15/RPL36/RPL21/RPS15/RPL11/RPS15A/RPL18A/RPL18/FAU/RPS19/RPL35A/RPL9/RPL13A/RPL29/RPS2/RPL38/RPL8/RPL5/RPL24/RPL3/RPL7/RPS16	33.3812463561303
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	55/108	238/9376	20.0622471210707	RPS27/RPL10/RPS4X/RPL37/RPL30/RPL39/RPS12/RPL12/RPL34/RPL41/RPL28/RPS8/RPL13/RPS28/RPS27A/RPS6/RPS13/RPL37A/RPL32/RPS21/RPS3A/RPS3/RPLP1/RPL19/RPS14/RPS24/RPL14/RPLP2/RPL6/RPS23/RPL35/RPS29/UBA52/RPL15/RPL36/RPL21/RPS15/RPL11/RPS15A/RPL18A/RPL18/FAU/RPS19/RPL35A/RPL9/RPL13A/RPL29/RPS2/RPL38/RPL8/RPL5/RPL24/RPL3/RPL7/RPS16	32.1544807296356
NA	NA	hsa04382	Cornified envelope formation	14/108	217/9376	5.60095579450418	S100A8/S100A6/S100A4/KRT24/KRT6A/SPRR3/KRT17/KRT14/S100A9/S100A11/KRT5/S100A16/S100A10/S100A14	7.40215886073058
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	8/108	195/9376	3.56163342830009	H3-3B/H3-3A/ACTB/H2AZ1/MACROH2A1/ACTG1/H2AZ2/H2AJ	3.90205869106007
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	6/108	117/9376	4.45204178537512	ACTB/H2AZ1/MACROH2A1/ACTG1/H2AZ2/H2AJ	4.05593920071108
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	6/108	143/9376	3.64257964257964	H3-3B/H3-3A/H2AZ1/MACROH2A1/H2AZ2/H2AJ	3.43739300902141
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	7/108	204/9376	2.97893972403776	IGF2/RPS6/ACTB/THBS1/LUM/DCN/ACTG1	3.08475111887196
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	6/108	168/9376	3.1005291005291	FTH1/H2AZ1/PPIA/MACROH2A1/H2AZ2/H2AJ	2.96554959554631
Human Diseases	Substance dependence	hsa05034	Alcoholism	6/108	191/9376	2.72716695753345	H3-3B/H3-3A/H2AZ1/MACROH2A1/H2AZ2/H2AJ	2.60325030290645
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	6/108	232/9376	2.24521072796935	TMSB4X/RGCC/ACTB/CFL1/ACTG1/CYRIB	2.07311426868068
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	6/108	235/9376	2.21654846335697	RPS6/ATP5F1E/ACTB/ACTG1/COX7A1/UQCRB	2.03878295726917
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	6/108	253/9376	2.05884936319719	H3-3B/H3-3A/RPS27A/ACTB/UBA52/ACTG1	1.84302024698863
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	4/108	139/9376	2.49826805222489	KRT24/KRT17/HSPA1A/KRT14	1.92103797824782
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	6/108	268/9376	1.94361525704809	RPS27A/ATP5F1E/UBA52/COX7A1/UQCRB/SNCA	1.69182463173884
NA	NA	hsa04519	Cadherin signaling	8/108	404/9376	1.71910524385772	KRT24/KRT6A/KRT17/KRT14/VIM/ACTB/KRT5/ACTG1	1.5949350760166
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	3/108	99/9376	2.6307519640853	KRT24/KRT17/KRT14	1.76078460594807
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	2/108	50/9376	3.47259259259259	HBB/THBS1	1.89231906047065
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	2/108	51/9376	3.40450254175744	ACTB/ACTG1	1.85861916782006
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	5/108	233/9376	1.86297885868701	VIM/ACTB/THBS1/DCN/ACTG1	1.43991965694235
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	2/108	56/9376	3.1005291005291	EEF1A1/HSPA1A	1.70184210122719
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	5/108	248/9376	1.75029868578256	RPS3/ACTB/GAPDH/ACTG1/S100A10	1.29263738983451
Metabolism	Energy metabolism	hsa00910	Nitrogen metabolism	1/108	17/9376	5.10675381263616	CA1	1.82941783808377
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	8/108	480/9376	1.44691358024691	RPS27A/ATP5F1E/UBA52/GPX1/COX7A1/UQCRB/SNCA/DKK1	1.08505383586513
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/108	70/9376	2.48042328042328	ACTB/ACTG1	1.34201665385352
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	4/108	200/9376	1.7362962962963	RPS3/ACTB/GAPDH/ACTG1	1.13617548579267
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	3/108	137/9376	1.90105433901054	ACTB/ACTG1/CTSW	1.14684119807605
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	4/108	205/9376	1.69394760614273	ATP5F1E/GAPDH/COX7A1/UQCRB	1.08442561931315
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	3/108	138/9376	1.88727858293076	ATP5F1E/COX7A1/UQCRB	1.13348314446186
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/108	75/9376	2.31506172839506	PERP/THBS1	1.23428784388073
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	2/108	76/9376	2.28460038986355	ACTB/ACTG1	1.21377412411101
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	2/108	78/9376	2.22602089268756	ACTB/ACTG1	1.17369405524045
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	4/108	212/9376	1.63801537386443	ACTB/THBS1/ACTG1/SKAP1	1.01428741605689
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	2/108	82/9376	2.11743450767841	HSPA1A/B2M	1.09706453117401
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	6/108	368/9376	1.41545893719807	ATP5F1E/ACTB/GPX1/ACTG1/COX7A1/UQCRB	0.877692383766909
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	2/108	86/9376	2.01894918173988	ACTB/ACTG1	1.02470391834251
NA	NA	hsa04518	Integrin signaling	3/108	154/9376	1.69119769119769	ACTB/THBS1/ACTG1	0.933586544362505
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	3/108	154/9376	1.69119769119769	MYL6/ACTB/ACTG1	0.933586544362505
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	3/108	155/9376	1.68028673835125	ACTB/THBS1/ACTG1	0.921877777801391
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	2/108	87/9376	1.99574286930609	COX7A1/UQCRB	1.00722582696972
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	6/108	388/9376	1.34249713631157	ATP5F1E/GAPDH/COX7A1/UQCRB/SNCA/DKK1	0.743782196918664
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	2/108	93/9376	1.86698526483473	ACTB/ACTG1	0.907013014659871
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/108	94/9376	1.84712371946414	S100A8/S100A9	0.891034439417967
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/108	170/9376	1.53202614379085	MYL6/ACTB/ACTG1	0.755660032925269
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	3/108	170/9376	1.53202614379085	IGF2/ACTB/ACTG1	0.755660032925269
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	2/108	99/9376	1.75383464272353	ACTB/ACTG1	0.813943790086113
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	2/108	105/9376	1.65361552028219	RPS27A/UBA52	0.727039854543681
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	2/108	105/9376	1.65361552028219	ACTB/ACTG1	0.727039854543681
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/108	37/9376	2.34634634634635	HBB	0.885751657768131
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	2/108	110/9376	1.57845117845118	RPS6/GAPDH	0.658751183107639
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/108	110/9376	1.57845117845118	THBS1/DCN	0.658751183107639
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/108	41/9376	2.11743450767841	THBS1	0.774036337556794
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/108	42/9376	2.06701940035273	FTH1	0.748113627886993
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	2/108	116/9376	1.49680715197957	ACTB/ACTG1	0.581186936428401
Cellular Processes	Cell motility	hsa04814	Motor proteins	3/108	194/9376	1.34249713631157	MYL6/ACTB/ACTG1	0.520347735328144
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	4/108	275/9376	1.26276094276094	HSPA1A/ATP5F1E/COX7A1/UQCRB	0.477405155365173
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/108	122/9376	1.42319368548877	ACTB/ACTG1	0.507877356086127
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/108	46/9376	1.88727858293076	FTH1	0.651182313024595
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	3/108	203/9376	1.28297755883963	ACTB/THBS1/ACTG1	0.43999609421284
Organismal Systems	Immune system	hsa04611	Platelet activation	2/108	126/9376	1.37801293356849	ACTB/ACTG1	0.461132327027739
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/108	138/9376	1.25818572195384	ACTB/ACTG1	0.329827823645587
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	4/108	308/9376	1.12746512746513	ATP5F1E/GPX1/COX7A1/UQCRB	0.245536177520984
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	3/108	227/9376	1.14733235438081	ATP5F1E/COX7A1/UQCRB	0.242565341245919
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/108	142/9376	1.22274387063119	RPS27A/UBA52	0.288708454982962
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/108	142/9376	1.22274387063119	ACTB/ACTG1	0.288708454982962
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/108	59/9376	1.47143753923415	GPX1	0.392117858981876
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/108	61/9376	1.42319368548877	FTH1	0.357945716973797
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/108	62/9376	1.40023894862605	HSPA1A	0.341312017849341
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/108	67/9376	1.29574350469873	GAPDH	0.262244026681494
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	2/108	157/9376	1.10592120783204	ACTB/ACTG1	0.144475879371153
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	2/108	157/9376	1.10592120783204	COX7A1/UQCRB	0.144475879371153
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/108	73/9376	1.18924403855911	PPIA	0.175217157451813
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/108	75/9376	1.15753086419753	GAPDH	0.147854983927132
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/108	75/9376	1.15753086419753	GPX1	0.147854983927132
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/108	169/9376	1.02739425816349	RPS27A/UBA52	0.0387925499804611
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	2/108	173/9376	1.00363947762792	ACTB/ACTG1	0.00521557143425683
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/108	78/9376	1.11301044634378	CFL1	0.108187135998151
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/108	78/9376	1.11301044634378	EEF1A1	0.108187135998151
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/108	80/9376	1.08518518518519	RPS6	0.0825972353732497
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/108	89/9376	0.975447357469829	THBS1	-0.0251223362870931
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/108	91/9376	0.954008954008954	IFITM1	-0.0475891044888634
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/108	196/9376	0.885865457294029	RPS27A/UBA52	-0.17431240766803
NA	NA	hsa04517	IgSF CAM signaling	3/108	299/9376	0.871051653660349	MYL6/ACTB/ACTG1	-0.244615913603261
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/108	201/9376	0.863829003132486	H3-3B/H3-3A	-0.210660985939975
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/108	98/9376	0.885865457294029	CFL1	-0.122604796336353
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	2/108	205/9376	0.846973803071364	VIM/B2M	-0.239132647632969
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/108	214/9376	0.811353409484251	B2M/CFL1	-0.301345844334694
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/108	108/9376	0.803840877914952	EEF1A1	-0.221325715927229
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/108	112/9376	0.775132275132275	HSPA1A	-0.258429071607044
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/108	115/9376	0.754911433172303	NACA	-0.285461493552435
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/108	116/9376	0.748403575989783	GAPDH	-0.294328602767082
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	2/108	250/9376	0.694518518518518	HSPA1A/SNX3	-0.528468570392126
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/108	133/9376	0.652742968532442	HCST	-0.435386436769533
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/108	134/9376	0.647871752349364	MYL6	-0.44317452302199
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	3/108	362/9376	0.719459791282996	IGF2/RPS6/THBS1	-0.587618049861092
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/108	136/9376	0.638344226579521	HSPA1A	-0.458599286239998
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/108	138/9376	0.629092860976919	RPS6	-0.473827497170687
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/108	140/9376	0.62010582010582	RPS6	-0.488865285746326
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/108	157/9376	0.552960603916018	THBS1	-0.609759000909434
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/108	158/9376	0.549460853258322	RPS6	-0.616520081553948
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	2/108	300/9376	0.578765432098765	IGF2/HSPA1A	-0.800464158478886
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/108	174/9376	0.498935717326522	HSPA1A	-0.720164085114662
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/108	178/9376	0.487723678734915	DKK1	-0.744855594519277
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/108	180/9376	0.482304526748971	B2M	-0.757034448204534
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/108	184/9376	0.471819645732689	CFL1	-0.781071246724486
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	2/108	323/9376	0.53755303290907	VIM/THBS1	-0.913001392428721
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/108	216/9376	0.401920438957476	HSPA1A	-0.959936716076905
NA	NA	hsa04081	Hormone signaling	1/108	219/9376	0.396414679519702	IGF2	-0.975637809983212
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	1/108	224/9376	0.387566137566138	B2M	-1.00145099490563
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/108	227/9376	0.382444118126938	B2M	-1.01673290876612
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/108	238/9376	0.364768129474012	IGF2	-1.0715185261186
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/108	243/9376	0.357262612406645	HSPA1A	-1.09580801998049
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/108	250/9376	0.347259259259259	CTSW	-1.12921072800568
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	1/108	333/9376	0.260705149594039	THBS1	-1.48281863681886