category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
NA	NA	hsa04382	Cornified envelope formation	9/71	217/9376	5.47699097812683	S100A6/KRT6A/S100A4/KRT24/SPRR3/KRT5/KRT14/KRT17/S100A8	5.82839102082835
NA	NA	hsa04519	Cadherin signaling	9/71	404/9376	2.94184911448891	KRT6A/KRT24/ARPC5/KRT5/VIM/PALS1/KRT14/KRT17/GABRB1	3.48512336164395
NA	NA	hsa04081	Hormone signaling	6/71	219/9376	3.61798186378545	CSHL1/CCK/CSH2/IGF2/CSH1/THRB	3.42427557266715
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	8/71	370/9376	2.85527217358203	CSHL1/CCK/CSH2/CSH1/GABRB1/KISS1/THRB/APELA	3.18052742955452
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	5/71	232/9376	2.84604176784847	RGCC/GSN/ARPC5/MYL12B/TMSB4X	2.48698995163954
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	3/71	99/9376	4.00170721297482	KRT24/KRT14/KRT17	2.62264054919093
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	3/71	110/9376	3.60153649167734	DCN/THBS1/RBX1	2.39737924181022
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	2/71	50/9376	5.28225352112676	THBS1/HBB	2.65195588637471
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	3/71	122/9376	3.24728700069268	CSHL1/CSH2/CSH1	2.18237979015254
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	4/71	204/9376	2.58933996133665	LUM/DCN/IGF2/THBS1	2.00473276126964
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	2/71	62/9376	4.25988187187642	CRYAB/SOD1	2.24950112465005
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	5/71	308/9376	2.14377172123651	SOD1/CLTB/MT-ND3/ATP5F1E/DNAH14	1.78285318467121
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	3/71	138/9376	2.87078995713411	MT-ND3/ATP5F1E/COX17	1.93389200475995
Genetic Information Processing	Translation	hsa03010	Ribosome	4/71	222/9376	2.37939347798503	RPS27/RPL37A/RPL21/RPS27L	1.81683641225675
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/71	139/9376	2.85013679197487	KRT24/KRT14/KRT17	1.91956309534141
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	3/71	142/9376	2.78992263439794	ELOB/RNF7/RBX1	1.87732784100218
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	2/71	70/9376	3.77303822937626	ELOB/RBX1	2.03413595593255
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	4/71	233/9376	2.26706159705011	DCN/CSRP1/THBS1/VIM	1.71075553063359
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	4/71	238/9376	2.21943425257427	RPS27/RPL37A/RPL21/RPS27L	1.66447744773442
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	2/71	78/9376	3.38605994944023	PAN3/ZCCHC7	1.84837678510363
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	2/71	78/9376	3.38605994944023	CLTB/ARPC5	1.84837678510363
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	2/71	79/9376	3.34319843109289	GSTP1/CBR3	1.82687074794912
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	4/71	250/9376	2.1129014084507	CLTB/ARPC5/DAB2/RNF103-CHMP3	1.55791259351861
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	4/71	253/9376	2.08784724155208	CAST/ARPC5/MYL12B/RBX1	1.53220177748072
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	2/71	82/9376	3.22088629336998	GSTP1/UPP1	1.76436542943167
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	3/71	168/9376	2.35814889336016	CSHL1/CSH2/CSH1	1.55158650438896
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/71	170/9376	2.33040596520298	ARPC5/MYL12B/PALS1	1.52907850308378
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	5/71	362/9376	1.82398256944985	CSHL1/CSH2/IGF2/THBS1/CSH1	1.39659395187324
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/71	89/9376	2.96755815793638	GABARAPL1/GABRB1	1.62907651419921
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	3/71	184/9376	2.15309246785058	RHOD/MYL12B/ABLIM1	1.3798270760794
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/71	98/9376	2.69502730669733	GSN/ARPC5	1.47339494869724
Cellular Processes	Cell motility	hsa04814	Motor proteins	3/71	194/9376	2.04210832002323	MYL12B/ACTA2/DNAH14	1.28115509429314
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	3/71	203/9376	1.95157149795324	THBS1/MYL12B/EMP1	1.19726523296711
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	2/71	110/9376	2.40102432778489	ELOB/RBX1	1.29107804232146
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/71	31/9376	4.25988187187642	SEC11C	1.58799701134861
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	1/71	32/9376	4.12676056338028	GABARAPL1	1.54760392975508
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	3/71	214/9376	1.85125707516125	ELOB/RNF7/RBX1	1.10034557508268
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/71	33/9376	4.00170721297482	VAMP8	1.50882457197631
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/71	34/9376	3.88400994200497	RBX1	1.47154282009781
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/71	37/9376	3.56909021697754	HBB	1.36768679399233
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	3/71	227/9376	1.74523794750884	SOD1/MT-ND3/ATP5F1E	0.992836419477147
Organismal Systems	Immune system	hsa04611	Platelet activation	2/71	126/9376	2.09613234965348	MYL12B/VAMP8	1.08201685273394
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	3/71	235/9376	1.68582559184897	MT-ND3/ATP5F1E/COX17	0.930052335003551
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	1/71	41/9376	3.22088629336998	BPGM	1.24485198117529
Human Diseases	Substance dependence	hsa05033	Nicotine addiction	1/71	41/9376	3.22088629336998	GABRB1	1.24485198117529
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/71	41/9376	3.22088629336998	THBS1	1.24485198117529
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/71	42/9376	3.14419852448021	SAT1	1.21650070112055
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/71	44/9376	3.00128040973111	ARHGDIB	1.16226066809007
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	2/71	140/9376	1.88651911468813	ACTA2/APELA	0.923138329501842
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	3/71	250/9376	1.58467605633803	CLTB/CTSW/VAMP8	0.81846800119146
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	5/71	480/9376	1.37558685446009	SOD1/DKK1/MT-ND3/ATP5F1E/DNAH14	0.737887645436235
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	4/71	368/9376	1.43539497856705	SOD1/MT-ND3/ATP5F1E/DNAH14	0.744302984459608
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	2/71	149/9376	1.77256829568012	MT-ND3/GABRB1	0.830340802632638
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/71	50/9376	2.64112676056338	SAT1	1.01633304788969
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/71	52/9376	2.53954496208017	HSD17B1	0.972410277105928
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	3/71	268/9376	1.47824258986756	SOD1/MT-ND3/ATP5F1E	0.693842278313491
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/71	53/9376	2.49162901939942	CLTB	0.951212481712911
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	3/71	275/9376	1.44061459667093	SOD1/MT-ND3/ATP5F1E	0.647794555979542
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/71	56/9376	2.35814889336016	GAS1	0.890410074689247
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/71	59/9376	2.23824301742659	UPP1	0.833394192078626
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/71	59/9376	2.23824301742659	GSTP1	0.833394192078626
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/71	169/9376	1.56279689974165	GABARAPL1/VAMP8	0.644900332636707
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	2/71	170/9376	1.55360397680199	IGF2/GSTP1	0.636274913289689
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	2/71	174/9376	1.51788894285252	CRYAB/RBX1	0.60231929007308
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/71	63/9376	2.09613234965348	SMYD3	0.762509207285546
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/71	63/9376	2.09613234965348	CBR3	0.762509207285546
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/71	63/9376	2.09613234965348	RBX1	0.762509207285546
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/71	65/9376	2.03163596966414	KISS1	0.72902364596241
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	2/71	178/9376	1.48377907896819	DKK1/RBX1	0.569202771089618
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	3/71	298/9376	1.32942622176009	CSHL1/CSH2/CSH1	0.504809863438719
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/71	66/9376	2.00085360648741	HSD17B1	0.71272880230442
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/71	67/9376	1.97099011982342	BPGM	0.69671846522159
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/71	70/9376	1.88651911468813	GSTP1	0.650297708738847
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/71	73/9376	1.80899093189273	GSTP1	0.606108252166867
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/71	75/9376	1.76075117370892	GSTP1	0.577783405604918
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/71	75/9376	1.76075117370892	THBS1	0.577783405604918
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/71	78/9376	1.69302997472012	IMPA2	0.536860155988175
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/71	79/9376	1.67159921554644	CLTB	0.523611208059374
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	2/71	205/9376	1.28835451734799	GSN/H2BC12	0.364629638657359
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	2/71	205/9376	1.28835451734799	MT-ND3/ATP5F1E	0.364629638657359
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/71	83/9376	1.59104021720686	SOD1	0.47242702663935
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/71	85/9376	1.55360397680199	UPP1	0.447851525474798
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/71	86/9376	1.53553881428103	CCK	0.43580172520169
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/71	89/9376	1.48377907896819	THBS1	0.400553921330892
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/71	91/9376	1.4511685497601	IFITM1	0.37776801488226
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/71	91/9376	1.4511685497601	GABRB1	0.37776801488226
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/71	93/9376	1.41996062395881	MYL12B	0.355518737632679
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	1/71	94/9376	1.40485465987414	S100A8	0.344587017347681
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/71	98/9376	1.34751365334866	IMPA2	0.302074697808201
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/71	102/9376	1.29466998066832	CCK	0.261371998474993
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/71	105/9376	1.25767940979209	GABARAPL1	0.23193575268411
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/71	106/9376	1.24581450969971	GSTP1	0.222319319178223
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	2/71	248/9376	1.0649704679691	ARPC5/MYL12B	0.0905754798357173
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	3/71	388/9376	1.02105416001162	DKK1/MT-ND3/ATP5F1E	0.0369980533248721
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/71	115/9376	1.14831598285364	GABRB1	0.139786282704247
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/71	116/9376	1.13841670713939	MYL12B	0.131029365651416
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/71	117/9376	1.12868664981341	MORF4L1	0.122349164334744
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/71	120/9376	1.10046948356808	ARHGDIB	0.0967541816008546
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/71	122/9376	1.08242900023089	THRB	0.0800482466952078
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/71	130/9376	1.01581798483207	ACTA2	0.0158636277450037
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/71	133/9376	0.992904797204278	GABARAPL1	-0.0071984796427142
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/71	134/9376	0.985495059911709	ACTA2	-0.0147720911999348
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/71	137/9376	0.963914876118022	CTSW	-0.0371648705501369
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/71	138/9376	0.95692998571137	RBX1	-0.0445227728318985
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/71	138/9376	0.95692998571137	ARPC5	-0.0445227728318985
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	1/71	142/9376	0.929974211465979	GSTP1	-0.0734452762799257
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/71	143/9376	0.923470895301881	H2BC12	-0.0805526546552627
NA	NA	hsa04517	IgSF CAM signaling	2/71	299/9376	0.883319986810495	ARPC5/MYL12B	-0.179109045639293
NA	NA	hsa04518	Integrin signaling	1/71	154/9376	0.857508688494604	THBS1	-0.155737360234718
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	1/71	155/9376	0.851976374375284	THBS1	-0.162317183885712
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/71	157/9376	0.841123172153943	THBS1	-0.175357805785313
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/71	157/9376	0.841123172153943	PALS1	-0.175357805785313
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/71	158/9376	0.835799607773222	RBX1	-0.181819728781206
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	2/71	323/9376	0.817686303579994	THBS1/VIM	-0.291260051056628
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	2/71	333/9376	0.793131159328342	THBS1/PALS1	-0.335751186246517
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/71	168/9376	0.786049631120054	RNF103-CHMP3	-0.244422762913619
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/71	187/9376	0.706183625819086	GABARAPL1	-0.3545024952277
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/71	191/9376	0.691394439938058	H2BC12	-0.376389477398414
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/71	195/9376	0.677211989888046	H2BC12	-0.397874705699961
NA	NA	hsa04082	Neuroactive ligand signaling	1/71	199/9376	0.663599688583764	GABRB1	-0.418976037766299
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/71	200/9376	0.660281690140845	ARPC5	-0.424193367659578
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/71	205/9376	0.644177258673995	VIM	-0.449944459996774
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/71	212/9376	0.622907254849854	THBS1	-0.485098789797641
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/71	238/9376	0.554858563143567	IGF2	-0.607599697265762
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	1/71	300/9376	0.44018779342723	IGF2	-0.860820045213927