ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003779 actin binding 64/1075 443/18639 0.144469525959368 2.50489999475038 9.5089907401924e-12 9.97493128646183e-09 GO:0045296 cadherin binding 50/1075 334/18639 0.149700598802395 2.59559949867706 5.27487238673323e-10 2.76667056684158e-07 GO:0005201 extracellular matrix structural constituent 30/1075 168/18639 0.178571428571429 3.09617940199336 2.86389566908788e-08 1.00140885229106e-05 GO:0043236 laminin binding 11/1075 29/18639 0.379310344827586 6.57671210906175 2.94961100918182e-07 7.73535487157933e-05 GO:0051015 actin filament binding 31/1075 209/18639 0.148325358851675 2.57175475687104 1.23448488414451e-06 0.000258994928693518 GO:0030695 GTPase regulator activity 54/1075 489/18639 0.110429447852761 1.91469253816522 3.49507227224249e-06 0.00055661943308259 GO:0060589 nucleoside-triphosphatase regulator activity 54/1075 490/18639 0.110204081632653 1.91078500237304 3.71433368119936e-06 0.00055661943308259 GO:0019838 growth factor binding 22/1075 136/18639 0.161764705882353 2.80477428180575 1.04529390515335e-05 0.00137064163313233 GO:0005178 integrin binding 24/1075 161/18639 0.149068322981366 2.58463671818576 1.75440633390914e-05 0.00204485804918966 GO:0140996 histone H3 kinase activity 41/1075 357/18639 0.11484593837535 1.991268321282 2.06606639179426e-05 0.00216730364499218 GO:0005516 calmodulin binding 28/1075 207/18639 0.135265700483092 2.34531850353893 2.33134808708866e-05 0.00219843578076312 GO:0035173 histone kinase activity 41/1075 360/18639 0.113888888888889 1.97467441860465 2.51489317151168e-05 0.00219843578076312 GO:0001968 fibronectin binding 9/1075 30/18639 0.3 5.20158139534884 3.24423829350315e-05 0.00261785074606524 GO:0031994 insulin-like growth factor I binding 6/1075 13/18639 0.461538461538462 8.00243291592129 4.38438793229678e-05 0.00327603448823617 GO:0005543 phospholipid binding 51/1075 497/18639 0.10261569416499 1.77921295213139 4.74493350756405e-05 0.00327603448823617 GO:0001618 virus receptor activity 15/1075 81/18639 0.185185185185185 3.21085271317829 5.30128339221626e-05 0.00327603448823617 GO:0005520 insulin-like growth factor binding 7/1075 19/18639 0.368421052631579 6.38790697674419 5.67913703777248e-05 0.00327603448823617 GO:0106310 protein serine kinase activity 40/1075 361/18639 0.110803324099723 1.92117503059976 5.83878206539699e-05 0.00327603448823617 GO:0140272 exogenous protein binding 15/1075 82/18639 0.182926829268293 3.17169597277368 6.14703117314918e-05 0.00327603448823617 GO:0005085 guanyl-nucleotide exchange factor activity 29/1075 230/18639 0.126086956521739 2.18617189079879 6.24601427690405e-05 0.00327603448823617 GO:0019903 protein phosphatase binding 21/1075 144/18639 0.145833333333333 2.52854651162791 7.97762799759388e-05 0.00388105849406492 GO:0141003 histone H2AX kinase activity 39/1075 354/18639 0.110169491525424 1.91018525817895 8.13949350518858e-05 0.00388105849406492 GO:0140375 immune receptor activity 22/1075 156/18639 0.141025641025641 2.44518783542039 9.07955483267607e-05 0.00403790254265354 GO:0004674 protein serine/threonine kinase activity 45/1075 433/18639 0.103926096997691 1.80193350878135 9.68884110049624e-05 0.00403790254265354 GO:0019902 phosphatase binding 25/1075 190/18639 0.131578947368421 2.28139534883721 9.86157962183019e-05 0.00403790254265354 GO:0050840 extracellular matrix binding 13/1075 67/18639 0.194029850746269 3.36420687261368 0.000100262654038354 0.00403790254265354 GO:0002020 protease binding 20/1075 136/18639 0.147058823529412 2.54979480164159 0.000103930761345706 0.00403790254265354 GO:0004896 cytokine receptor activity 16/1075 96/18639 0.166666666666667 2.88976744186047 0.000113185518022028 0.00424041458589668 GO:1901981 phosphatidylinositol phosphate binding 24/1075 185/18639 0.12972972972973 2.24933249528598 0.000167932183412433 0.00607451242757386 GO:0002162 dystroglycan binding 5/1075 11/18639 0.454545454545455 7.88118393234672 0.000217995772938466 0.00762258552708168 GO:0035091 phosphatidylinositol binding 32/1075 284/18639 0.112676056338028 1.95364559449722 0.000228685590701718 0.0077384253111646 GO:0000146 microfilament motor activity 9/1075 38/18639 0.236842105263158 4.10651162790698 0.000243591347788944 0.00798522886970631 GO:0019207 kinase regulator activity 32/1075 287/18639 0.111498257839721 1.93322421197634 0.000276518223752462 0.0087899277792828 GO:0051020 GTPase binding 34/1075 315/18639 0.107936507936508 1.87146843853821 0.000332797298690269 0.0102677754801792 GO:0005539 glycosaminoglycan binding 28/1075 242/18639 0.115702479338843 2.00611954641553 0.000357051194341278 0.0107013343675429 GO:0098641 cadherin binding involved in cell-cell adhesion 6/1075 18/18639 0.333333333333333 5.77953488372093 0.000369531511320104 0.0107677376492997 GO:0004713 protein tyrosine kinase activity 19/1075 140/18639 0.135714285714286 2.35309634551495 0.000438204735734949 0.0123667974289094 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 9/1075 41/18639 0.219512195121951 3.80603516732842 0.00044798694213399 0.0123667974289094 GO:0001786 phosphatidylserine binding 11/1075 59/18639 0.186440677966102 3.23262120614899 0.00048545061521296 0.0130573768040614 GO:0043548 phosphatidylinositol 3-kinase binding 7/1075 26/18639 0.269230769230769 4.66808586762075 0.000519587067365591 0.0136261708416626 GO:0004857 enzyme inhibitor activity 41/1075 416/18639 0.0985576923076923 1.70885286225403 0.000581445030861895 0.0148764838383934 GO:0097110 scaffold protein binding 12/1075 70/18639 0.171428571428571 2.97233222591362 0.00060751906975375 0.0151735120040877 GO:0048306 calcium-dependent protein binding 13/1075 80/18639 0.1625 2.81752325581395 0.000622191835420245 0.0151785868687404 GO:0030020 extracellular matrix structural constituent conferring tensile strength 9/1075 44/18639 0.204545454545455 3.54653276955603 0.000775966747536741 0.0184997526855918 GO:0035401 histone H3Y41 kinase activity 16/1075 115/18639 0.139130434782609 2.41232760364004 0.000918560097190961 0.0204553323397065 GO:0140801 histone H2AXY142 kinase activity 16/1075 115/18639 0.139130434782609 2.41232760364004 0.000918560097190961 0.0204553323397065 GO:0009931 calcium-dependent protein serine/threonine kinase activity 6/1075 21/18639 0.285714285714286 4.95388704318937 0.00093057804721368 0.0204553323397065 GO:0008201 heparin binding 21/1075 172/18639 0.122093023255814 2.11692266089778 0.000935992328222984 0.0204553323397065 GO:0043394 proteoglycan binding 8/1075 37/18639 0.216216216216216 3.74888749214331 0.00102860973425988 0.0220206451273187 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 5/1075 15/18639 0.333333333333333 5.77953488372093 0.00116713864660536 0.0240064400056672 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 5/1075 15/18639 0.333333333333333 5.77953488372093 0.00116713864660536 0.0240064400056672 GO:0030527 structural constituent of chromatin 14/1075 98/18639 0.142857142857143 2.47694352159468 0.001448561536379 0.0292219433011841 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 5/1075 16/18639 0.3125 5.41831395348837 0.00161760457087079 0.0320163621668577 GO:0046332 SMAD binding 12/1075 79/18639 0.151898734177215 2.6337120989108 0.00181731707395084 0.0353030668624895 GO:0045309 protein phosphorylated amino acid binding 10/1075 59/18639 0.169491525423729 2.93874655104454 0.00185451678816741 0.0353706929234112 GO:0005096 GTPase activator activity 28/1075 271/18639 0.103321033210332 1.79144254698361 0.00206269259151319 0.0375332052950729 GO:0004812 aminoacyl-tRNA ligase activity 8/1075 41/18639 0.195121951219512 3.38314237095859 0.00207523918695351 0.0375332052950729 GO:0016875 ligase activity, forming carbon-oxygen bonds 8/1075 41/18639 0.195121951219512 3.38314237095859 0.00207523918695351 0.0375332052950729 GO:0051787 misfolded protein binding 5/1075 17/18639 0.294117647058824 5.09958960328317 0.00218371660929146 0.0388257410702837 GO:0035403 histone H3T6 kinase activity 26/1075 247/18639 0.105263157894737 1.82511627906977 0.00225940952389013 0.0395020098426791 GO:0043178 alcohol binding 13/1075 92/18639 0.141304347826087 2.45002022244692 0.00233110606430113 0.0400873813352767 GO:0015026 coreceptor activity 10/1075 61/18639 0.163934426229508 2.84239420510865 0.00239889663723367 0.0405877834267439 GO:0051219 phosphoprotein binding 13/1075 93/18639 0.139784946236559 2.42367591897974 0.00257018320757837 0.0421024198622492 GO:0003953 NAD+ nucleosidase activity 4/1075 11/18639 0.363636363636364 6.30494714587738 0.00261792778933833 0.0421024198622492 GO:0019215 intermediate filament binding 4/1075 11/18639 0.363636363636364 6.30494714587738 0.00261792778933833 0.0421024198622492 GO:0005518 collagen binding 11/1075 72/18639 0.152777777777778 2.64895348837209 0.00264896063956954 0.0421024198622492 GO:0031543 peptidyl-proline dioxygenase activity 4/1075 12/18639 0.333333333333333 5.77953488372093 0.00374890283797298 0.0586955086124426 GO:0004715 non-membrane spanning protein tyrosine kinase activity 8/1075 45/18639 0.177777777777778 3.08241860465116 0.00381930822091769 0.0589184459373919 GO:0017022 myosin binding 11/1075 76/18639 0.144736842105263 2.50953488372093 0.00407297486072249 0.0610364375556841 GO:0098631 cell adhesion mediator activity 11/1075 76/18639 0.144736842105263 2.50953488372093 0.00407297486072249 0.0610364375556841 GO:0140857 histone H3T45 kinase activity 25/1075 246/18639 0.101626016260163 1.7620533182076 0.00430862844787045 0.063658468194593 GO:0031418 L-ascorbic acid binding 5/1075 20/18639 0.25 4.3346511627907 0.00473656576317971 0.0690091317441044 GO:0046982 protein heterodimerization activity 34/1075 369/18639 0.0921409214092141 1.59759500850822 0.00483146734343482 0.0694275238803167 GO:0005200 structural constituent of cytoskeleton 14/1075 112/18639 0.125 2.16732558139535 0.00506884201205417 0.071361892809341 GO:0019209 kinase activator activity 17/1075 148/18639 0.114864864864865 1.99159648020113 0.00516587244094114 0.071361892809341 GO:0004535 poly(A)-specific ribonuclease activity 4/1075 13/18639 0.307692307692308 5.33495527728086 0.00517016573261193 0.071361892809341 GO:0003785 actin monomer binding 6/1075 29/18639 0.206896551724138 3.58729751403368 0.00548917324466536 0.0738223427391534 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 6/1075 29/18639 0.206896551724138 3.58729751403368 0.00548917324466536 0.0738223427391534 GO:0140297 DNA-binding transcription factor binding 42/1075 488/18639 0.0860655737704918 1.49225695768204 0.00631648441931657 0.0809988074000717 GO:0019887 protein kinase regulator activity 25/1075 255/18639 0.0980392156862745 1.69986320109439 0.006784090211647 0.0809988074000717 GO:0042043 neurexin family protein binding 4/1075 14/18639 0.285714285714286 4.95388704318937 0.00691156759828374 0.0809988074000717 GO:0044548 S100 protein binding 4/1075 14/18639 0.285714285714286 4.95388704318937 0.00691156759828374 0.0809988074000717 GO:0031267 small GTPase binding 27/1075 283/18639 0.0954063604240283 1.65421316459857 0.00719735218910251 0.0809988074000717 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 24/1075 243/18639 0.0987654320987654 1.71245478036176 0.00721077797497354 0.0809988074000717 GO:0008970 phospholipase A1 activity 5/1075 22/18639 0.227272727272727 3.94059196617336 0.00731072200870187 0.0809988074000717 GO:0019208 phosphatase regulator activity 14/1075 117/18639 0.11965811965812 2.07470483005367 0.00744605679715114 0.0809988074000717 GO:0004676 3-phosphoinositide-dependent protein kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0004711 ribosomal protein S6 kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0035175 histone H3S10 kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0035979 histone H2AXS139 kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0044022 histone H3S28 kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0044023 histone H4S1 kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0044024 histone H2AS1 kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0044025 histone H2BS14 kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0072354 histone H3T3 kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0072371 histone H2AS121 kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0072518 Rho-dependent protein serine/threonine kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0140823 histone H2BS36 kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0140855 histone H3S57 kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0140995 histone H2A kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0140997 histone H4 kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0140998 histone H2B kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:1990244 histone H2AT120 kinase activity 24/1075 245/18639 0.0979591836734694 1.69847555766493 0.00795317174662287 0.0809988074000717 GO:0004677 DNA-dependent protein kinase activity 24/1075 246/18639 0.0975609756097561 1.6915711854793 0.00834717642756905 0.0841941160819225 GO:0019888 protein phosphatase regulator activity 13/1075 107/18639 0.121495327102804 2.10655944359922 0.00857151250765042 0.0856334916240503 GO:0035402 histone H3T11 kinase activity 24/1075 247/18639 0.097165991902834 1.68472271914132 0.00875698235576862 0.0866610801056725 GO:0005523 tropomyosin binding 4/1075 15/18639 0.266666666666667 4.62362790697674 0.0090004508534395 0.0882380649089536 GO:0004679 AMP-activated protein kinase activity 24/1075 248/18639 0.0967741935483871 1.67792948237059 0.00918304391408016 0.0887650576018947 GO:1901681 sulfur compound binding 26/1075 275/18639 0.0945454545454545 1.63928625792812 0.00922344259161727 0.0887650576018947 GO:0005080 protein kinase C binding 8/1075 52/18639 0.153846153846154 2.66747763864043 0.0093544763347445 0.0892076879558816 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 11/1075 86/18639 0.127906976744186 2.21772850189291 0.0103413980023953 0.0977308694100243 GO:0030296 protein tyrosine kinase activator activity 6/1075 33/18639 0.181818181818182 3.15247357293869 0.0105226419805781 0.0978401945256293 GO:0017171 serine hydrolase activity 20/1075 198/18639 0.101010101010101 1.75137420718816 0.0106051144821661 0.0978401945256293 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 5/1075 24/18639 0.208333333333333 3.61220930232558 0.010726046111008 0.0978401945256293 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 5/1075 24/18639 0.208333333333333 3.61220930232558 0.010726046111008 0.0978401945256293 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 4/1075 16/18639 0.25 4.3346511627907 0.0114613996142957 0.102406729429943 GO:0030246 carbohydrate binding 26/1075 280/18639 0.0928571428571429 1.61001328903654 0.0114807608658482 0.102406729429943 GO:1902936 phosphatidylinositol bisphosphate binding 13/1075 111/18639 0.117117117117117 2.03064739157762 0.0115195367709565 0.102406729429943 GO:0004866 endopeptidase inhibitor activity 17/1075 161/18639 0.105590062111801 1.83078434204825 0.0116886075828391 0.103036549196624 GO:0001223 transcription coactivator binding 7/1075 44/18639 0.159090909090909 2.75841437632135 0.012275088575197 0.10730473262818 GO:0003707 nuclear steroid receptor activity 5/1075 25/18639 0.2 3.46772093023256 0.0127846050124162 0.110835129405162 GO:0004252 serine-type endopeptidase activity 18/1075 176/18639 0.102272727272727 1.77326638477801 0.0131629707876774 0.11317997013339 GO:0019210 kinase inhibitor activity 11/1075 90/18639 0.122222222222222 2.11916279069767 0.0142966519468993 0.11918697462097 GO:0030295 protein kinase activator activity 15/1075 139/18639 0.107913669064748 1.87107244437009 0.0142983765255149 0.11918697462097 GO:0036041 long-chain fatty acid binding 4/1075 17/18639 0.235294117647059 4.07967168262654 0.0143160713081432 0.11918697462097 GO:0038191 neuropilin binding 4/1075 17/18639 0.235294117647059 4.07967168262654 0.0143160713081432 0.11918697462097 GO:0004112 cyclic-nucleotide phosphodiesterase activity 5/1075 26/18639 0.192307692307692 3.33434704830054 0.0150943972685204 0.124551599186659 GO:0001221 transcription coregulator binding 13/1075 115/18639 0.11304347826087 1.96001617795753 0.0151979072410794 0.124551599186659 GO:0072341 modified amino acid binding 11/1075 91/18639 0.120879120879121 2.09587528750319 0.0154431640298681 0.125289183378758 GO:0030276 clathrin binding 7/1075 46/18639 0.152173913043478 2.63848331648129 0.0155267815436021 0.125289183378758 GO:0019911 structural constituent of myelin sheath 3/1075 10/18639 0.3 5.20158139534884 0.0169108743334131 0.133422108223444 GO:0035374 chondroitin sulfate binding 3/1075 10/18639 0.3 5.20158139534884 0.0169108743334131 0.133422108223444 GO:0008236 serine-type peptidase activity 19/1075 194/18639 0.0979381443298969 1.6981107648046 0.0169162444172717 0.133422108223444 GO:0001784 phosphotyrosine residue binding 7/1075 47/18639 0.148936170212766 2.58234537357744 0.0173630341357638 0.135924050809076 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 5/1075 27/18639 0.185185185185185 3.21085271317829 0.0176672271681257 0.137280898513807 GO:0030414 peptidase inhibitor activity 17/1075 169/18639 0.100591715976331 1.74411999449567 0.0181769188880118 0.140202852305326 GO:0019955 cytokine binding 15/1075 144/18639 0.104166666666667 1.80610465116279 0.0191928682744133 0.146958531531822 GO:0061135 endopeptidase regulator activity 18/1075 184/18639 0.0978260869565217 1.6961678463094 0.0199102671830628 0.151346886050963 GO:0045499 chemorepellent activity 5/1075 28/18639 0.178571428571429 3.09617940199336 0.0205138705601161 0.15481331091771 GO:0061134 peptidase regulator activity 21/1075 226/18639 0.0929203539823009 1.61110928174522 0.0213499990228148 0.159972492678091 GO:0015173 aromatic amino acid transmembrane transporter activity 3/1075 11/18639 0.272727272727273 4.72871035940803 0.0222707292874412 0.161117207051902 GO:0032050 clathrin heavy chain binding 3/1075 11/18639 0.272727272727273 4.72871035940803 0.0222707292874412 0.161117207051902 GO:0034056 estrogen response element binding 3/1075 11/18639 0.272727272727273 4.72871035940803 0.0222707292874412 0.161117207051902 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 3/1075 11/18639 0.272727272727273 4.72871035940803 0.0222707292874412 0.161117207051902 GO:0048407 platelet-derived growth factor binding 3/1075 11/18639 0.272727272727273 4.72871035940803 0.0222707292874412 0.161117207051902 GO:0005010 insulin-like growth factor receptor activity 7/1075 51/18639 0.137254901960784 2.37980848153215 0.0262385364116375 0.188522086957588 GO:0031624 ubiquitin conjugating enzyme binding 5/1075 30/18639 0.166666666666667 2.88976744186047 0.0270662182954245 0.193146006747621 GO:0008081 phosphoric diester hydrolase activity 10/1075 87/18639 0.114942528735632 1.99294306335205 0.0279155986542319 0.197605697600595 GO:0004126 cytidine deaminase activity 3/1075 12/18639 0.25 4.3346511627907 0.0284446714372639 0.197605697600595 GO:0005095 GTPase inhibitor activity 3/1075 12/18639 0.25 4.3346511627907 0.0284446714372639 0.197605697600595 GO:0045295 gamma-catenin binding 3/1075 12/18639 0.25 4.3346511627907 0.0284446714372639 0.197605697600595 GO:0051010 microtubule plus-end binding 4/1075 21/18639 0.19047619047619 3.30259136212625 0.029998699482007 0.207030498398851 GO:0042578 phosphoric ester hydrolase activity 30/1075 363/18639 0.0826446280991736 1.43294253315395 0.0305639327926487 0.209552715682931 GO:0003774 cytoskeletal motor activity 15/1075 153/18639 0.0980392156862745 1.69986320109439 0.0310787000633302 0.211698417963853 GO:0005246 calcium channel regulator activity 7/1075 53/18639 0.132075471698113 2.29000438788943 0.0316633338269612 0.212915622977451 GO:0038064 collagen receptor activity 7/1075 53/18639 0.132075471698113 2.29000438788943 0.0316633338269612 0.212915622977451 GO:0016247 channel regulator activity 16/1075 168/18639 0.0952380952380952 1.65129568106312 0.033569663469493 0.224296668659224 GO:0043425 bHLH transcription factor binding 5/1075 32/18639 0.15625 2.70915697674419 0.0348151645350437 0.227993541613152 GO:0005243 gap junction channel activity 4/1075 22/18639 0.181818181818182 3.15247357293869 0.0350404722538526 0.227993541613152 GO:0050321 tau-protein kinase activity 4/1075 22/18639 0.181818181818182 3.15247357293869 0.0350404722538526 0.227993541613152 GO:0019199 transmembrane receptor protein kinase activity 9/1075 78/18639 0.115384615384615 2.00060822898032 0.0351476537269913 0.227993541613152 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 3/1075 13/18639 0.230769230769231 4.00121645796064 0.0354270231486595 0.227993541613152 GO:0045159 myosin II binding 3/1075 13/18639 0.230769230769231 4.00121645796064 0.0354270231486595 0.227993541613152 GO:0048156 tau protein binding 6/1075 43/18639 0.13953488372093 2.41934018388318 0.0356751789275816 0.228190626189226 GO:0141108 transporter regulator activity 16/1075 170/18639 0.0941176470588235 1.63186867305062 0.0368445661466963 0.234242120532633 GO:0140311 protein sequestering activity 5/1075 33/18639 0.151515151515152 2.62706131078224 0.0391531149911983 0.247299740165327 GO:0043014 alpha-tubulin binding 6/1075 44/18639 0.136363636363636 2.36435517970402 0.0393699300358528 0.247299740165327 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 4/1075 23/18639 0.173913043478261 3.01540950455005 0.040542474643309 0.253149142266852 GO:0019992 diacylglycerol binding 3/1075 14/18639 0.214285714285714 3.71541528239203 0.0432039655714892 0.263836797325037 GO:0032036 myosin heavy chain binding 3/1075 14/18639 0.214285714285714 3.71541528239203 0.0432039655714892 0.263836797325037 GO:0034236 protein kinase A catalytic subunit binding 3/1075 14/18639 0.214285714285714 3.71541528239203 0.0432039655714892 0.263836797325037 GO:0140303 intramembrane lipid transporter activity 6/1075 45/18639 0.133333333333333 2.31181395348837 0.0432987296837272 0.263836797325037 GO:0099106 ion channel regulator activity 15/1075 160/18639 0.09375 1.62549418604651 0.0435116929811548 0.263836797325037 GO:0030215 semaphorin receptor binding 4/1075 24/18639 0.166666666666667 2.88976744186047 0.0465057603497691 0.27561888478479 GO:0030552 cAMP binding 4/1075 24/18639 0.166666666666667 2.88976744186047 0.0465057603497691 0.27561888478479 GO:0050699 WW domain binding 4/1075 24/18639 0.166666666666667 2.88976744186047 0.0465057603497691 0.27561888478479 GO:0070300 phosphatidic acid binding 4/1075 24/18639 0.166666666666667 2.88976744186047 0.0465057603497691 0.27561888478479 GO:0030291 protein serine/threonine kinase inhibitor activity 6/1075 46/18639 0.130434782608696 2.26155712841254 0.0474645219047459 0.27972069369707 GO:0005154 epidermal growth factor receptor binding 5/1075 35/18639 0.142857142857143 2.47694352159468 0.0487750155835772 0.284696108992204 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 28/1075 349/18639 0.0802292263610315 1.39106283734257 0.0488515725630092 0.284696108992204 GO:0030165 PDZ domain binding 9/1075 83/18639 0.108433734939759 1.88008966096946 0.0492908854187413 0.285669275161655 GO:0008252 nucleotidase activity 3/1075 15/18639 0.2 3.46772093023256 0.0517548442510016 0.292533488935116 GO:0031005 filamin binding 3/1075 15/18639 0.2 3.46772093023256 0.0517548442510016 0.292533488935116 GO:0051371 muscle alpha-actinin binding 3/1075 15/18639 0.2 3.46772093023256 0.0517548442510016 0.292533488935116 GO:0120283 protein serine/threonine kinase binding 3/1075 15/18639 0.2 3.46772093023256 0.0517548442510016 0.292533488935116 GO:0005504 fatty acid binding 6/1075 47/18639 0.127659574468085 2.2134388916378 0.0518696176758165 0.292533488935116 GO:0004879 nuclear receptor activity 7/1075 59/18639 0.11864406779661 2.05712258573118 0.0522609324371666 0.293164268056619 GO:0044389 ubiquitin-like protein ligase binding 26/1075 322/18639 0.0807453416149068 1.40001155568395 0.0526251290544055 0.293637023287614 GO:0019211 phosphatase activator activity 4/1075 25/18639 0.16 2.77417674418605 0.052928837556884 0.293769050778684 GO:0004869 cysteine-type endopeptidase inhibitor activity 5/1075 36/18639 0.138888888888889 2.40813953488372 0.054063032427735 0.296922099563843 GO:0044390 ubiquitin-like protein conjugating enzyme binding 5/1075 36/18639 0.138888888888889 2.40813953488372 0.054063032427735 0.296922099563843 GO:0004725 protein tyrosine phosphatase activity 10/1075 98/18639 0.102040816326531 1.76924537256763 0.055948112155982 0.302406469201692 GO:0004714 transmembrane receptor protein tyrosine kinase activity 7/1075 60/18639 0.116666666666667 2.02283720930233 0.056353433299198 0.302406469201692 GO:0098531 ligand-modulated transcription factor activity 7/1075 60/18639 0.116666666666667 2.02283720930233 0.056353433299198 0.302406469201692 GO:0015631 tubulin binding 30/1075 385/18639 0.0779220779220779 1.35106010268801 0.0582463670257984 0.302406469201692 GO:0022829 wide pore channel activity 5/1075 37/18639 0.135135135135135 2.34305468258957 0.0596698780571869 0.302406469201692 GO:0030280 structural constituent of skin epidermis 5/1075 37/18639 0.135135135135135 2.34305468258957 0.0596698780571869 0.302406469201692 GO:0005227 calcium-activated cation channel activity 4/1075 26/18639 0.153846153846154 2.66747763864043 0.0598078267002228 0.302406469201692 GO:0019865 immunoglobulin binding 4/1075 26/18639 0.153846153846154 2.66747763864043 0.0598078267002228 0.302406469201692 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 22/1075 268/18639 0.082089552238806 1.42331829225963 0.060868479910366 0.302406469201692 GO:0019841 retinol binding 3/1075 16/18639 0.1875 3.25098837209302 0.0610533314748568 0.302406469201692 GO:0140327 flippase activity 3/1075 16/18639 0.1875 3.25098837209302 0.0610533314748568 0.302406469201692 GO:0001222 transcription corepressor binding 6/1075 49/18639 0.122448979591837 2.12309444708116 0.0614037921257964 0.302406469201692 GO:0005004 GPI-linked ephrin receptor activity 6/1075 49/18639 0.122448979591837 2.12309444708116 0.0614037921257964 0.302406469201692 GO:0005008 hepatocyte growth factor receptor activity 6/1075 49/18639 0.122448979591837 2.12309444708116 0.0614037921257964 0.302406469201692 GO:0005009 insulin receptor activity 6/1075 49/18639 0.122448979591837 2.12309444708116 0.0614037921257964 0.302406469201692 GO:0005011 macrophage colony-stimulating factor receptor activity 6/1075 49/18639 0.122448979591837 2.12309444708116 0.0614037921257964 0.302406469201692 GO:0005018 platelet-derived growth factor alpha-receptor activity 6/1075 49/18639 0.122448979591837 2.12309444708116 0.0614037921257964 0.302406469201692 GO:0005020 stem cell factor receptor activity 6/1075 49/18639 0.122448979591837 2.12309444708116 0.0614037921257964 0.302406469201692 GO:0008288 boss receptor activity 6/1075 49/18639 0.122448979591837 2.12309444708116 0.0614037921257964 0.302406469201692 GO:0036332 placental growth factor receptor activity 6/1075 49/18639 0.122448979591837 2.12309444708116 0.0614037921257964 0.302406469201692 GO:0038062 protein tyrosine kinase collagen receptor activity 6/1075 49/18639 0.122448979591837 2.12309444708116 0.0614037921257964 0.302406469201692 GO:0060175 brain-derived neurotrophic factor receptor activity 6/1075 49/18639 0.122448979591837 2.12309444708116 0.0614037921257964 0.302406469201692 GO:0005006 epidermal growth factor receptor activity 6/1075 50/18639 0.12 2.08063255813953 0.066534329822467 0.321633695777732 GO:0005007 fibroblast growth factor receptor activity 6/1075 50/18639 0.12 2.08063255813953 0.066534329822467 0.321633695777732 GO:0005017 platelet-derived growth factor receptor activity 6/1075 50/18639 0.12 2.08063255813953 0.066534329822467 0.321633695777732 GO:0005019 platelet-derived growth factor beta-receptor activity 6/1075 50/18639 0.12 2.08063255813953 0.066534329822467 0.321633695777732 GO:0017124 SH3 domain binding 11/1075 115/18639 0.0956521739130435 1.65847522750253 0.0679369240987243 0.326907492566797 GO:0003924 GTPase activity 26/1075 331/18639 0.0785498489425982 1.36194477622427 0.0684149205809808 0.327704345613922 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 9/1075 89/18639 0.101123595505618 1.75334204337601 0.0706560569186641 0.332293173078543 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 9/1075 89/18639 0.101123595505618 1.75334204337601 0.0706560569186641 0.332293173078543 GO:0030169 low-density lipoprotein particle binding 3/1075 17/18639 0.176470588235294 3.0597537619699 0.0710684586534384 0.332293173078543 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 3/1075 17/18639 0.176470588235294 3.0597537619699 0.0710684586534384 0.332293173078543 GO:0031489 myosin V binding 3/1075 17/18639 0.176470588235294 3.0597537619699 0.0710684586534384 0.332293173078543 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 5/1075 39/18639 0.128205128205128 2.22289803220036 0.0718357266455063 0.332293173078543 GO:0005021 vascular endothelial growth factor receptor activity 6/1075 51/18639 0.117647058823529 2.03983584131327 0.0719071022772442 0.332293173078543 GO:0005030 neurotrophin receptor activity 6/1075 51/18639 0.117647058823529 2.03983584131327 0.0719071022772442 0.332293173078543 GO:0140793 histone H2AXY142 phosphatase activity 9/1075 90/18639 0.1 1.73386046511628 0.0746994699252308 0.343133332638022 GO:0046875 ephrin receptor binding 4/1075 28/18639 0.142857142857143 2.47694352159468 0.0749070859619704 0.343133332638022 GO:0070064 proline-rich region binding 3/1075 18/18639 0.166666666666667 2.88976744186047 0.0817655309110898 0.37130754080404 GO:1901611 phosphatidylglycerol binding 3/1075 18/18639 0.166666666666667 2.88976744186047 0.0817655309110898 0.37130754080404 GO:0001217 DNA-binding transcription repressor activity 22/1075 278/18639 0.079136690647482 1.37211979253806 0.0827631548286439 0.372174061049869 GO:0005003 ephrin receptor activity 6/1075 53/18639 0.113207547169811 1.96286090390522 0.0833755046203235 0.372174061049869 GO:0005005 transmembrane-ephrin receptor activity 6/1075 53/18639 0.113207547169811 1.96286090390522 0.0833755046203235 0.372174061049869 GO:0005544 calcium-dependent phospholipid binding 6/1075 53/18639 0.113207547169811 1.96286090390522 0.0833755046203235 0.372174061049869 GO:0008013 beta-catenin binding 10/1075 106/18639 0.0943396226415094 1.63571741992102 0.0851206273809816 0.377345152490433 GO:0017080 sodium channel regulator activity 5/1075 41/18639 0.121951219512195 2.11446398184912 0.0852533852623762 0.377345152490433 GO:0015485 cholesterol binding 6/1075 54/18639 0.111111111111111 1.92651162790698 0.0894677386660254 0.394334696893532 GO:0005319 lipid transporter activity 15/1075 178/18639 0.0842696629213483 1.46111836948001 0.090642282800729 0.397839977648388 GO:0022839 monoatomic ion-gated channel activity 4/1075 30/18639 0.133333333333333 2.31181395348837 0.091731170857341 0.39842535241414 GO:0001664 G protein-coupled receptor binding 23/1075 297/18639 0.0774410774410774 1.34272022551092 0.0927565648041412 0.39842535241414 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 3/1075 19/18639 0.157894736842105 2.73767441860465 0.0931069350344299 0.39842535241414 GO:0016918 retinal binding 3/1075 19/18639 0.157894736842105 2.73767441860465 0.0931069350344299 0.39842535241414 GO:0042800 histone H3K4 methyltransferase activity 3/1075 19/18639 0.157894736842105 2.73767441860465 0.0931069350344299 0.39842535241414 GO:0043395 heparan sulfate proteoglycan binding 3/1075 19/18639 0.157894736842105 2.73767441860465 0.0931069350344299 0.39842535241414 GO:0005496 steroid binding 10/1075 108/18639 0.0925925925925926 1.60542635658915 0.0936289210137407 0.39842535241414 GO:0044325 transmembrane transporter binding 12/1075 136/18639 0.0882352941176471 1.52987688098495 0.0938141678229671 0.39842535241414 GO:0098632 cell-cell adhesion mediator activity 6/1075 55/18639 0.109090909090909 1.89148414376321 0.0957954495843146 0.401565112408521 GO:0140313 molecular sequestering activity 6/1075 55/18639 0.109090909090909 1.89148414376321 0.0957954495843146 0.401565112408521 GO:0005548 phospholipid transporter activity 7/1075 68/18639 0.102941176470588 1.78485636114911 0.0960846932455089 0.401565112408521 GO:0032934 sterol binding 7/1075 68/18639 0.102941176470588 1.78485636114911 0.0960846932455089 0.401565112408521 GO:0004867 serine-type endopeptidase inhibitor activity 9/1075 95/18639 0.0947368421052632 1.64260465116279 0.0970084242510685 0.403816813648297 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 35/1075 484/18639 0.0723140495867769 1.25382471650971 0.0994021175827208 0.412145538910174 GO:0017147 Wnt-protein binding 4/1075 31/18639 0.129032258064516 2.23723930982746 0.100759808438367 0.414498192360185 GO:0047499 calcium-independent phospholipase A2 activity 4/1075 31/18639 0.129032258064516 2.23723930982746 0.100759808438367 0.414498192360185 GO:0016505 peptidase activator activity involved in apoptotic process 3/1075 20/18639 0.15 2.60079069767442 0.105052850974188 0.423367454116963 GO:0031625 ubiquitin protein ligase binding 23/1075 302/18639 0.076158940397351 1.32048975820114 0.106029104276239 0.423367454116963 GO:0001046 core promoter sequence-specific DNA binding 5/1075 44/18639 0.113636363636364 1.97029598308668 0.107646593075314 0.423367454116963 GO:0016248 channel inhibitor activity 5/1075 44/18639 0.113636363636364 1.97029598308668 0.107646593075314 0.423367454116963 GO:0030547 signaling receptor inhibitor activity 5/1075 44/18639 0.113636363636364 1.97029598308668 0.107646593075314 0.423367454116963 GO:0005031 tumor necrosis factor receptor activity 2/1075 10/18639 0.2 3.46772093023256 0.109966548087922 0.423367454116963 GO:0005131 growth hormone receptor binding 2/1075 10/18639 0.2 3.46772093023256 0.109966548087922 0.423367454116963 GO:0008140 cAMP response element binding protein binding 2/1075 10/18639 0.2 3.46772093023256 0.109966548087922 0.423367454116963 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/1075 10/18639 0.2 3.46772093023256 0.109966548087922 0.423367454116963 GO:0031419 cobalamin binding 2/1075 10/18639 0.2 3.46772093023256 0.109966548087922 0.423367454116963 GO:0031434 mitogen-activated protein kinase kinase binding 2/1075 10/18639 0.2 3.46772093023256 0.109966548087922 0.423367454116963 GO:0047429 nucleoside triphosphate diphosphatase activity 2/1075 10/18639 0.2 3.46772093023256 0.109966548087922 0.423367454116963 GO:0050815 phosphoserine residue binding 2/1075 10/18639 0.2 3.46772093023256 0.109966548087922 0.423367454116963 GO:0070739 protein-glutamic acid ligase activity 2/1075 10/18639 0.2 3.46772093023256 0.109966548087922 0.423367454116963 GO:0070740 tubulin-glutamic acid ligase activity 2/1075 10/18639 0.2 3.46772093023256 0.109966548087922 0.423367454116963 GO:0140999 histone H3K4 trimethyltransferase activity 2/1075 10/18639 0.2 3.46772093023256 0.109966548087922 0.423367454116963 GO:0047498 calcium-dependent phospholipase A2 activity 4/1075 32/18639 0.125 2.16732558139535 0.110180471853128 0.423367454116963 GO:0051059 NF-kappaB binding 4/1075 32/18639 0.125 2.16732558139535 0.110180471853128 0.423367454116963 GO:0004860 protein kinase inhibitor activity 8/1075 84/18639 0.0952380952380952 1.65129568106312 0.110859385294731 0.424421515234206 GO:0001216 DNA-binding transcription activator activity 35/1075 491/18639 0.0712830957230143 1.23594941505234 0.114641875236909 0.437306644085519 GO:0141110 transporter inhibitor activity 5/1075 45/18639 0.111111111111111 1.92651162790698 0.115690075999263 0.438738919599464 GO:0005126 cytokine receptor binding 21/1075 275/18639 0.0763636363636364 1.32403890063425 0.115853842449048 0.438738919599464 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/1075 21/18639 0.142857142857143 2.47694352159468 0.117561876222885 0.438869779921019 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 3/1075 21/18639 0.142857142857143 2.47694352159468 0.117561876222885 0.438869779921019 GO:0005123 death receptor binding 3/1075 21/18639 0.142857142857143 2.47694352159468 0.117561876222885 0.438869779921019 GO:0072542 protein phosphatase activator activity 3/1075 21/18639 0.142857142857143 2.47694352159468 0.117561876222885 0.438869779921019 GO:0019956 chemokine binding 4/1075 33/18639 0.121212121212121 2.10164904862579 0.11997734866167 0.439908461425287 GO:0071889 14-3-3 protein binding 4/1075 33/18639 0.121212121212121 2.10164904862579 0.11997734866167 0.439908461425287 GO:0042379 chemokine receptor binding 7/1075 72/18639 0.0972222222222222 1.6856976744186 0.120541325843645 0.439908461425287 GO:0043130 ubiquitin binding 9/1075 100/18639 0.09 1.56047441860465 0.122766508260625 0.439908461425287 GO:0070888 E-box binding 6/1075 59/18639 0.101694915254237 1.76324793062672 0.123391583528414 0.439908461425287 GO:0035591 signaling adaptor activity 11/1075 129/18639 0.0852713178294574 1.47848566792861 0.125460335617485 0.439908461425287 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 2/1075 11/18639 0.181818181818182 3.15247357293869 0.129454507821363 0.439908461425287 GO:0034713 type I transforming growth factor beta receptor binding 2/1075 11/18639 0.181818181818182 3.15247357293869 0.129454507821363 0.439908461425287 GO:0042608 T cell receptor binding 2/1075 11/18639 0.181818181818182 3.15247357293869 0.129454507821363 0.439908461425287 GO:0045294 alpha-catenin binding 2/1075 11/18639 0.181818181818182 3.15247357293869 0.129454507821363 0.439908461425287 GO:0050786 RAGE receptor binding 2/1075 11/18639 0.181818181818182 3.15247357293869 0.129454507821363 0.439908461425287 GO:0050998 nitric-oxide synthase binding 2/1075 11/18639 0.181818181818182 3.15247357293869 0.129454507821363 0.439908461425287 GO:0008376 acetylgalactosaminyltransferase activity 4/1075 34/18639 0.117647058823529 2.03983584131327 0.130133591718832 0.439908461425287 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 4/1075 34/18639 0.117647058823529 2.03983584131327 0.130133591718832 0.439908461425287 GO:0030332 cyclin binding 4/1075 34/18639 0.117647058823529 2.03983584131327 0.130133591718832 0.439908461425287 GO:0031683 G-protein beta/gamma-subunit complex binding 3/1075 22/18639 0.136363636363636 2.36435517970402 0.130591571586417 0.439908461425287 GO:0032931 histone H3K56 acetyltransferase activity 3/1075 22/18639 0.136363636363636 2.36435517970402 0.130591571586417 0.439908461425287 GO:0043992 histone H3K9 acetyltransferase activity 3/1075 22/18639 0.136363636363636 2.36435517970402 0.130591571586417 0.439908461425287 GO:0043993 histone H3K18 acetyltransferase activity 3/1075 22/18639 0.136363636363636 2.36435517970402 0.130591571586417 0.439908461425287 GO:0043994 histone H3K23 acetyltransferase activity 3/1075 22/18639 0.136363636363636 2.36435517970402 0.130591571586417 0.439908461425287 GO:0043999 histone H2AK5 acetyltransferase activity 3/1075 22/18639 0.136363636363636 2.36435517970402 0.130591571586417 0.439908461425287 GO:0044012 histone H2AK9 acetyltransferase activity 3/1075 22/18639 0.136363636363636 2.36435517970402 0.130591571586417 0.439908461425287 GO:0044014 histone H2BK5 acetyltransferase activity 3/1075 22/18639 0.136363636363636 2.36435517970402 0.130591571586417 0.439908461425287 GO:0044015 histone H2BK12 acetyltransferase activity 3/1075 22/18639 0.136363636363636 2.36435517970402 0.130591571586417 0.439908461425287 GO:0044016 histone H3K4 acetyltransferase activity 3/1075 22/18639 0.136363636363636 2.36435517970402 0.130591571586417 0.439908461425287 GO:0044017 histone H3K27 acetyltransferase activity 3/1075 22/18639 0.136363636363636 2.36435517970402 0.130591571586417 0.439908461425287 GO:0044018 histone H3K36 acetyltransferase activity 3/1075 22/18639 0.136363636363636 2.36435517970402 0.130591571586417 0.439908461425287 GO:0046972 histone H4K16 acetyltransferase activity 3/1075 22/18639 0.136363636363636 2.36435517970402 0.130591571586417 0.439908461425287 GO:0140908 histone H3K122 acetyltransferase activity 3/1075 22/18639 0.136363636363636 2.36435517970402 0.130591571586417 0.439908461425287 GO:0005125 cytokine activity 18/1075 234/18639 0.0769230769230769 1.33373881932021 0.130822743240704 0.439908461425287 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 6/1075 60/18639 0.1 1.73386046511628 0.130840266887216 0.439908461425287 GO:0140938 histone H3 methyltransferase activity 5/1075 47/18639 0.106382978723404 1.84453240969817 0.132598437885742 0.444395403649021 GO:1990782 protein tyrosine kinase binding 10/1075 117/18639 0.0854700854700855 1.48193202146691 0.137868288341386 0.460585460095904 GO:0000175 3'-5'-RNA exonuclease activity 4/1075 35/18639 0.114285714285714 1.98155481727575 0.140631472510478 0.46309629020057 GO:0004623 phospholipase A2 activity 4/1075 35/18639 0.114285714285714 1.98155481727575 0.140631472510478 0.46309629020057 GO:0005283 amino acid:sodium symporter activity 3/1075 23/18639 0.130434782608696 2.26155712841254 0.144098936127883 0.46309629020057 GO:0017134 fibroblast growth factor binding 3/1075 23/18639 0.130434782608696 2.26155712841254 0.144098936127883 0.46309629020057 GO:0042171 lysophosphatidic acid acyltransferase activity 3/1075 23/18639 0.130434782608696 2.26155712841254 0.144098936127883 0.46309629020057 GO:0044013 histone H2B acetyltransferase activity 3/1075 23/18639 0.130434782608696 2.26155712841254 0.144098936127883 0.46309629020057 GO:0071617 lysophospholipid acyltransferase activity 3/1075 23/18639 0.130434782608696 2.26155712841254 0.144098936127883 0.46309629020057 GO:0015179 L-amino acid transmembrane transporter activity 6/1075 62/18639 0.0967741935483871 1.67792948237059 0.146360613243986 0.46309629020057 GO:0005025 transforming growth factor beta receptor activity, type I 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0005026 transforming growth factor beta receptor activity, type II 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0005078 MAP-kinase scaffold activity 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0005165 neurotrophin receptor binding 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0008504 monoamine transmembrane transporter activity 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0010853 cyclase activator activity 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0015269 calcium-activated potassium channel activity 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0016273 arginine N-methyltransferase activity 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0016274 protein-arginine N-methyltransferase activity 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0016361 activin receptor activity, type I 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0016362 activin receptor activity, type II 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0017002 activin receptor activity 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0017166 vinculin binding 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0034452 dynactin binding 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0035497 cAMP response element binding 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0070679 inositol 1,4,5 trisphosphate binding 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:1990817 poly(A) RNA polymerase activity 2/1075 12/18639 0.166666666666667 2.88976744186047 0.149656475098182 0.46309629020057 GO:0005484 SNAP receptor activity 4/1075 36/18639 0.111111111111111 1.92651162790698 0.151452527520821 0.467275592262768 GO:0032182 ubiquitin-like protein binding 10/1075 120/18639 0.0833333333333333 1.44488372093023 0.154697665007102 0.475888124904546 GO:0004622 lysophospholipase activity 3/1075 24/18639 0.125 2.16732558139535 0.158040818381899 0.481932611868058 GO:0035035 histone acetyltransferase binding 3/1075 24/18639 0.125 2.16732558139535 0.158040818381899 0.481932611868058 GO:0043998 histone H2A acetyltransferase activity 3/1075 24/18639 0.125 2.16732558139535 0.158040818381899 0.481932611868058 GO:0032813 tumor necrosis factor receptor superfamily binding 5/1075 50/18639 0.1 1.73386046511628 0.159874953338219 0.484707589745063 GO:0048020 CCR chemokine receptor binding 5/1075 50/18639 0.1 1.73386046511628 0.159874953338219 0.484707589745063 GO:0140789 histone phosphatase activity 11/1075 136/18639 0.0808823529411765 1.40238714090287 0.161957522404271 0.487268583752178 GO:0016791 phosphatase activity 20/1075 273/18639 0.0732600732600733 1.27022744697163 0.16225586918932 0.487268583752178 GO:0030551 cyclic nucleotide binding 4/1075 37/18639 0.108108108108108 1.87444374607165 0.162577697152776 0.487268583752178 GO:0042805 actinin binding 4/1075 37/18639 0.108108108108108 1.87444374607165 0.162577697152776 0.487268583752178 GO:0051213 dioxygenase activity 8/1075 93/18639 0.0860215053763441 1.4914928732183 0.167644993753137 0.489798121132758 GO:0016874 ligase activity 13/1075 167/18639 0.0778443113772455 1.34971173931207 0.167702766568867 0.489798121132758 GO:0033293 monocarboxylic acid binding 7/1075 79/18639 0.0886075949367089 1.53633205769797 0.170112061552061 0.489798121132758 GO:0002161 aminoacyl-tRNA editing activity 2/1075 13/18639 0.153846153846154 2.66747763864043 0.170425466361732 0.489798121132758 GO:0004465 lipoprotein lipase activity 2/1075 13/18639 0.153846153846154 2.66747763864043 0.170425466361732 0.489798121132758 GO:0005035 death receptor activity 2/1075 13/18639 0.153846153846154 2.66747763864043 0.170425466361732 0.489798121132758 GO:0008253 5'-nucleotidase activity 2/1075 13/18639 0.153846153846154 2.66747763864043 0.170425466361732 0.489798121132758 GO:0019855 calcium channel inhibitor activity 2/1075 13/18639 0.153846153846154 2.66747763864043 0.170425466361732 0.489798121132758 GO:0031432 titin binding 2/1075 13/18639 0.153846153846154 2.66747763864043 0.170425466361732 0.489798121132758 GO:0035673 oligopeptide transmembrane transporter activity 2/1075 13/18639 0.153846153846154 2.66747763864043 0.170425466361732 0.489798121132758 GO:0039706 co-receptor binding 2/1075 13/18639 0.153846153846154 2.66747763864043 0.170425466361732 0.489798121132758 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 2/1075 13/18639 0.153846153846154 2.66747763864043 0.170425466361732 0.489798121132758 GO:0070123 transforming growth factor beta receptor activity, type III 2/1075 13/18639 0.153846153846154 2.66747763864043 0.170425466361732 0.489798121132758 GO:0089720 caspase binding 2/1075 13/18639 0.153846153846154 2.66747763864043 0.170425466361732 0.489798121132758 GO:0140333 glycerophospholipid flippase activity 2/1075 13/18639 0.153846153846154 2.66747763864043 0.170425466361732 0.489798121132758 GO:0004709 MAP kinase kinase kinase activity 3/1075 25/18639 0.12 2.08063255813953 0.172374270312583 0.493277952033409 GO:0005109 frizzled binding 4/1075 38/18639 0.105263157894737 1.82511627906977 0.173987456865931 0.493277952033409 GO:0005501 retinoid binding 4/1075 38/18639 0.105263157894737 1.82511627906977 0.173987456865931 0.493277952033409 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 4/1075 38/18639 0.105263157894737 1.82511627906977 0.173987456865931 0.493277952033409 GO:0019840 isoprenoid binding 4/1075 38/18639 0.105263157894737 1.82511627906977 0.173987456865931 0.493277952033409 GO:0140101 catalytic activity, acting on a tRNA 11/1075 139/18639 0.079136690647482 1.37211979253806 0.179057537314231 0.506283980168809 GO:0005112 Notch binding 3/1075 26/18639 0.115384615384615 2.00060822898032 0.187056849914195 0.520774283078457 GO:0005160 transforming growth factor beta receptor binding 3/1075 26/18639 0.115384615384615 2.00060822898032 0.187056849914195 0.520774283078457 GO:0050681 nuclear androgen receptor binding 3/1075 26/18639 0.115384615384615 2.00060822898032 0.187056849914195 0.520774283078457 GO:0050750 low-density lipoprotein particle receptor binding 3/1075 26/18639 0.115384615384615 2.00060822898032 0.187056849914195 0.520774283078457 GO:0016500 protein-hormone receptor activity 6/1075 67/18639 0.0895522388059701 1.55271086428324 0.18849863911195 0.520774283078457 GO:0004864 protein phosphatase inhibitor activity 5/1075 53/18639 0.0943396226415094 1.63571741992102 0.189198179361834 0.520774283078457 GO:0004065 arylsulfatase activity 2/1075 14/18639 0.142857142857143 2.47694352159468 0.191629049826773 0.520774283078457 GO:0004705 JUN kinase activity 2/1075 14/18639 0.142857142857143 2.47694352159468 0.191629049826773 0.520774283078457 GO:0008191 metalloendopeptidase inhibitor activity 2/1075 14/18639 0.142857142857143 2.47694352159468 0.191629049826773 0.520774283078457 GO:0008195 phosphatidate phosphatase activity 2/1075 14/18639 0.142857142857143 2.47694352159468 0.191629049826773 0.520774283078457 GO:0019763 immunoglobulin receptor activity 2/1075 14/18639 0.142857142857143 2.47694352159468 0.191629049826773 0.520774283078457 GO:0032454 histone H3K9 demethylase activity 2/1075 14/18639 0.142857142857143 2.47694352159468 0.191629049826773 0.520774283078457 GO:0042813 Wnt receptor activity 2/1075 14/18639 0.142857142857143 2.47694352159468 0.191629049826773 0.520774283078457 GO:0098821 BMP receptor activity 2/1075 14/18639 0.142857142857143 2.47694352159468 0.191629049826773 0.520774283078457 GO:1901474 azole transmembrane transporter activity 2/1075 14/18639 0.142857142857143 2.47694352159468 0.191629049826773 0.520774283078457 GO:1990841 promoter-specific chromatin binding 6/1075 68/18639 0.0882352941176471 1.52987688098495 0.197441924195799 0.532808550336663 GO:0004532 RNA exonuclease activity 4/1075 40/18639 0.1 1.73386046511628 0.197581054414644 0.532808550336663 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 4/1075 40/18639 0.1 1.73386046511628 0.197581054414644 0.532808550336663 GO:0003925 G protein activity 5/1075 54/18639 0.0925925925925926 1.60542635658915 0.199374754943039 0.536266969064738 GO:0004683 calcium/calmodulin-dependent protein kinase activity 3/1075 27/18639 0.111111111111111 1.92651162790698 0.202046877826113 0.54206438577901 GO:0031490 chromatin DNA binding 10/1075 128/18639 0.078125 1.35457848837209 0.204177452420641 0.54638302956442 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/1075 41/18639 0.0975609756097561 1.6915711854793 0.20972458621489 0.558378403399541 GO:0042169 SH2 domain binding 4/1075 41/18639 0.0975609756097561 1.6915711854793 0.20972458621489 0.558378403399541 GO:0033130 acetylcholine receptor binding 2/1075 15/18639 0.133333333333333 2.31181395348837 0.213148158376891 0.564627318528683 GO:0045504 dynein heavy chain binding 2/1075 15/18639 0.133333333333333 2.31181395348837 0.213148158376891 0.564627318528683 GO:0036408 histone H3K14 acetyltransferase activity 3/1075 28/18639 0.107142857142857 1.85770764119601 0.21730365284981 0.569878829598627 GO:0051393 alpha-actinin binding 3/1075 28/18639 0.107142857142857 1.85770764119601 0.21730365284981 0.569878829598627 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 3/1075 28/18639 0.107142857142857 1.85770764119601 0.21730365284981 0.569878829598627 GO:0141052 histone H3 demethylase activity 3/1075 28/18639 0.107142857142857 1.85770764119601 0.21730365284981 0.569878829598627 GO:0019212 phosphatase inhibitor activity 5/1075 56/18639 0.0892857142857143 1.54808970099668 0.220259855960044 0.57519467802197 GO:0008307 structural constituent of muscle 4/1075 42/18639 0.0952380952380952 1.65129568106312 0.222072301810198 0.57519467802197 GO:0031492 nucleosomal DNA binding 4/1075 42/18639 0.0952380952380952 1.65129568106312 0.222072301810198 0.57519467802197 GO:0042056 chemoattractant activity 4/1075 42/18639 0.0952380952380952 1.65129568106312 0.222072301810198 0.57519467802197 GO:0048487 beta-tubulin binding 4/1075 42/18639 0.0952380952380952 1.65129568106312 0.222072301810198 0.57519467802197 GO:0005262 calcium channel activity 10/1075 131/18639 0.0763358778625954 1.32355760695899 0.224280233256919 0.579482671641647 GO:0015085 calcium ion transmembrane transporter activity 11/1075 147/18639 0.0748299319727891 1.2974466065496 0.228468392361433 0.588853424047035 GO:0016504 peptidase activator activity 5/1075 57/18639 0.087719298245614 1.52093023255814 0.230944032618218 0.589437594115429 GO:0005416 amino acid:monoatomic cation symporter activity 3/1075 29/18639 0.103448275862069 1.79364875701684 0.232787630811432 0.589437594115429 GO:0010484 histone H3 acetyltransferase activity 3/1075 29/18639 0.103448275862069 1.79364875701684 0.232787630811432 0.589437594115429 GO:0004712 protein serine/threonine/tyrosine kinase activity 4/1075 43/18639 0.0930232558139535 1.61289345592212 0.234604037240343 0.589437594115429 GO:0008200 ion channel inhibitor activity 4/1075 43/18639 0.0930232558139535 1.61289345592212 0.234604037240343 0.589437594115429 GO:0004707 MAP kinase activity 2/1075 16/18639 0.125 2.16732558139535 0.234875990791467 0.589437594115429 GO:0004708 MAP kinase kinase activity 2/1075 16/18639 0.125 2.16732558139535 0.234875990791467 0.589437594115429 GO:0005024 transforming growth factor beta receptor activity 2/1075 16/18639 0.125 2.16732558139535 0.234875990791467 0.589437594115429 GO:0015562 efflux transmembrane transporter activity 2/1075 16/18639 0.125 2.16732558139535 0.234875990791467 0.589437594115429 GO:0022858 alanine transmembrane transporter activity 2/1075 16/18639 0.125 2.16732558139535 0.234875990791467 0.589437594115429 GO:0140328 floppase activity 2/1075 16/18639 0.125 2.16732558139535 0.234875990791467 0.589437594115429 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 13/1075 181/18639 0.0718232044198895 1.24531414621611 0.24611865553924 0.613259150060804 GO:0019842 vitamin binding 11/1075 150/18639 0.0733333333333333 1.2714976744186 0.248259053704958 0.613259150060804 GO:0032452 histone demethylase activity 3/1075 30/18639 0.1 1.73386046511628 0.248460570806331 0.613259150060804 GO:0043995 histone H4K5 acetyltransferase activity 3/1075 30/18639 0.1 1.73386046511628 0.248460570806331 0.613259150060804 GO:0043996 histone H4K8 acetyltransferase activity 3/1075 30/18639 0.1 1.73386046511628 0.248460570806331 0.613259150060804 GO:0043997 histone H4K12 acetyltransferase activity 3/1075 30/18639 0.1 1.73386046511628 0.248460570806331 0.613259150060804 GO:0048019 receptor antagonist activity 3/1075 30/18639 0.1 1.73386046511628 0.248460570806331 0.613259150060804 GO:0048029 monosaccharide binding 6/1075 74/18639 0.0810810810810811 1.40583280955374 0.254053415011166 0.623370666285389 GO:0008484 sulfuric ester hydrolase activity 2/1075 17/18639 0.117647058823529 2.03983584131327 0.256716995076538 0.623370666285389 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/1075 17/18639 0.117647058823529 2.03983584131327 0.256716995076538 0.623370666285389 GO:0015278 intracellularly gated calcium channel activity 2/1075 17/18639 0.117647058823529 2.03983584131327 0.256716995076538 0.623370666285389 GO:0030548 acetylcholine receptor regulator activity 2/1075 17/18639 0.117647058823529 2.03983584131327 0.256716995076538 0.623370666285389 GO:0045236 CXCR chemokine receptor binding 2/1075 17/18639 0.117647058823529 2.03983584131327 0.256716995076538 0.623370666285389 GO:0070492 oligosaccharide binding 2/1075 17/18639 0.117647058823529 2.03983584131327 0.256716995076538 0.623370666285389 GO:0005164 tumor necrosis factor receptor binding 3/1075 31/18639 0.0967741935483871 1.67792948237059 0.264285652488613 0.635861581331549 GO:0016411 acylglycerol O-acyltransferase activity 3/1075 31/18639 0.0967741935483871 1.67792948237059 0.264285652488613 0.635861581331549 GO:0070325 lipoprotein particle receptor binding 3/1075 31/18639 0.0967741935483871 1.67792948237059 0.264285652488613 0.635861581331549 GO:0140457 protein demethylase activity 3/1075 31/18639 0.0967741935483871 1.67792948237059 0.264285652488613 0.635861581331549 GO:0000149 SNARE binding 8/1075 106/18639 0.0754716981132075 1.30857393593681 0.267618249408066 0.642406278327371 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/1075 18/18639 0.111111111111111 1.92651162790698 0.278585928097219 0.659100265796813 GO:0004706 JUN kinase kinase kinase activity 2/1075 18/18639 0.111111111111111 1.92651162790698 0.278585928097219 0.659100265796813 GO:0015172 acidic amino acid transmembrane transporter activity 2/1075 18/18639 0.111111111111111 1.92651162790698 0.278585928097219 0.659100265796813 GO:0031690 adrenergic receptor binding 2/1075 18/18639 0.111111111111111 1.92651162790698 0.278585928097219 0.659100265796813 GO:0099602 neurotransmitter receptor regulator activity 2/1075 18/18639 0.111111111111111 1.92651162790698 0.278585928097219 0.659100265796813 GO:1990381 ubiquitin-specific protease binding 2/1075 18/18639 0.111111111111111 1.92651162790698 0.278585928097219 0.659100265796813 GO:0022884 macromolecule transmembrane transporter activity 3/1075 32/18639 0.09375 1.62549418604651 0.280227567726767 0.659100265796813 GO:0071813 lipoprotein particle binding 3/1075 32/18639 0.09375 1.62549418604651 0.280227567726767 0.659100265796813 GO:0071814 protein-lipid complex binding 3/1075 32/18639 0.09375 1.62549418604651 0.280227567726767 0.659100265796813 GO:0031406 carboxylic acid binding 13/1075 187/18639 0.0695187165775401 1.2053575425942 0.283386757326672 0.665039616187201 GO:0004620 phospholipase activity 8/1075 109/18639 0.073394495412844 1.27255813953488 0.292862864220176 0.685743626265546 GO:0043177 organic acid binding 13/1075 189/18639 0.0687830687830688 1.19260243632337 0.296189057453492 0.688050062060549 GO:0019239 deaminase activity 3/1075 33/18639 0.0909090909090909 1.57623678646934 0.296252589633276 0.688050062060549 GO:0042562 hormone binding 7/1075 94/18639 0.074468085106383 1.29117268678872 0.298638802683331 0.688050062060549 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 4/1075 48/18639 0.0833333333333333 1.44488372093023 0.299332023824735 0.688050062060549 GO:0032266 phosphatidylinositol-3-phosphate binding 4/1075 48/18639 0.0833333333333333 1.44488372093023 0.299332023824735 0.688050062060549 GO:0022821 solute:potassium antiporter activity 2/1075 19/18639 0.105263157894737 1.82511627906977 0.300406986104606 0.688050062060549 GO:0030506 ankyrin binding 2/1075 19/18639 0.105263157894737 1.82511627906977 0.300406986104606 0.688050062060549 GO:0042577 lipid phosphatase activity 2/1075 19/18639 0.105263157894737 1.82511627906977 0.300406986104606 0.688050062060549 GO:0050145 nucleoside monophosphate kinase activity 2/1075 19/18639 0.105263157894737 1.82511627906977 0.300406986104606 0.688050062060549 GO:0140036 ubiquitin-modified protein reader activity 2/1075 19/18639 0.105263157894737 1.82511627906977 0.300406986104606 0.688050062060549 GO:0004721 phosphoprotein phosphatase activity 12/1075 175/18639 0.0685714285714286 1.18893289036545 0.310150034041559 0.708817833789968 GO:0051427 hormone receptor binding 3/1075 34/18639 0.0882352941176471 1.52987688098495 0.312328621689513 0.709682336605834 GO:0016763 pentosyltransferase activity 4/1075 49/18639 0.0816326530612245 1.41539629805411 0.312557902299233 0.709682336605834 GO:0035254 glutamate receptor binding 4/1075 49/18639 0.0816326530612245 1.41539629805411 0.312557902299233 0.709682336605834 GO:0004175 endopeptidase activity 26/1075 405/18639 0.0641975308641975 1.11309560723514 0.313724303805049 0.71079221315658 GO:0120013 lipid transfer activity 5/1075 65/18639 0.0769230769230769 1.33373881932021 0.320595684290118 0.717402416505165 GO:0001614 purinergic nucleotide receptor activity 2/1075 20/18639 0.1 1.73386046511628 0.322113001119097 0.717402416505165 GO:0001972 retinoic acid binding 2/1075 20/18639 0.1 1.73386046511628 0.322113001119097 0.717402416505165 GO:0010851 cyclase regulator activity 2/1075 20/18639 0.1 1.73386046511628 0.322113001119097 0.717402416505165 GO:0015095 magnesium ion transmembrane transporter activity 2/1075 20/18639 0.1 1.73386046511628 0.322113001119097 0.717402416505165 GO:0016502 nucleotide receptor activity 2/1075 20/18639 0.1 1.73386046511628 0.322113001119097 0.717402416505165 GO:0030742 GTP-dependent protein binding 2/1075 20/18639 0.1 1.73386046511628 0.322113001119097 0.717402416505165 GO:0140939 histone H4 methyltransferase activity 2/1075 20/18639 0.1 1.73386046511628 0.322113001119097 0.717402416505165 GO:0015101 organic cation transmembrane transporter activity 6/1075 81/18639 0.0740740740740741 1.28434108527132 0.324716734860719 0.721669184044268 GO:0005343 organic acid:sodium symporter activity 3/1075 35/18639 0.0857142857142857 1.48616611295681 0.328425229425048 0.726831362166404 GO:0010485 histone H4 acetyltransferase activity 3/1075 35/18639 0.0857142857142857 1.48616611295681 0.328425229425048 0.726831362166404 GO:0008017 microtubule binding 18/1075 276/18639 0.0652173913043478 1.13077856420627 0.329170903772005 0.726947953803859 GO:0010314 phosphatidylinositol-5-phosphate binding 2/1075 21/18639 0.0952380952380952 1.65129568106312 0.343644698476593 0.75118741805677 GO:0015174 basic amino acid transmembrane transporter activity 2/1075 21/18639 0.0952380952380952 1.65129568106312 0.343644698476593 0.75118741805677 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/1075 21/18639 0.0952380952380952 1.65129568106312 0.343644698476593 0.75118741805677 GO:0051428 peptide hormone receptor binding 2/1075 21/18639 0.0952380952380952 1.65129568106312 0.343644698476593 0.75118741805677 GO:0042054 histone methyltransferase activity 5/1075 67/18639 0.0746268656716418 1.29392572023603 0.343727321894423 0.75118741805677 GO:0045505 dynein intermediate chain binding 3/1075 36/18639 0.0833333333333333 1.44488372093023 0.344513656870887 0.751340594714262 GO:0001540 amyloid-beta binding 6/1075 83/18639 0.072289156626506 1.25339310731297 0.345439310462189 0.751796341649038 GO:0000287 magnesium ion binding 15/1075 230/18639 0.0652173913043478 1.13077856420627 0.349332390391712 0.758694984515333 GO:0030159 signaling receptor complex adaptor activity 4/1075 52/18639 0.0769230769230769 1.33373881932021 0.352472668974107 0.763933532549253 GO:0004527 exonuclease activity 6/1075 84/18639 0.0714285714285714 1.23847176079734 0.355848219865767 0.768075684442778 GO:0051117 ATPase binding 6/1075 84/18639 0.0714285714285714 1.23847176079734 0.355848219865767 0.768075684442778 GO:0023023 MHC protein complex binding 3/1075 37/18639 0.0810810810810811 1.40583280955374 0.360566829787191 0.776662432128877 GO:0015377 chloride:monoatomic cation symporter activity 2/1075 22/18639 0.0909090909090909 1.57623678646934 0.36495001116561 0.779699718355856 GO:0016881 acid-amino acid ligase activity 2/1075 22/18639 0.0909090909090909 1.57623678646934 0.36495001116561 0.779699718355856 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/1075 22/18639 0.0909090909090909 1.57623678646934 0.36495001116561 0.779699718355856 GO:0140035 ubiquitin-like protein reader activity 2/1075 22/18639 0.0909090909090909 1.57623678646934 0.36495001116561 0.779699718355856 GO:0051018 protein kinase A binding 4/1075 53/18639 0.0754716981132075 1.30857393593681 0.365801198738375 0.779929791619014 GO:0016279 protein-lysine N-methyltransferase activity 5/1075 69/18639 0.072463768115942 1.25642062689585 0.36696211304924 0.780817964682866 GO:0043531 ADP binding 3/1075 38/18639 0.0789473684210526 1.36883720930233 0.376559347466155 0.798345650902199 GO:0016209 antioxidant activity 6/1075 86/18639 0.0697674418604651 1.20967009194159 0.37672173231324 0.798345650902199 GO:0016278 lysine N-methyltransferase activity 5/1075 70/18639 0.0714285714285714 1.23847176079734 0.378591285858975 0.800690038036421 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/1075 23/18639 0.0869565217391304 1.50770475227503 0.385983446883489 0.804963490617853 GO:0004602 glutathione peroxidase activity 2/1075 23/18639 0.0869565217391304 1.50770475227503 0.385983446883489 0.804963490617853 GO:0005158 insulin receptor binding 2/1075 23/18639 0.0869565217391304 1.50770475227503 0.385983446883489 0.804963490617853 GO:0005212 structural constituent of eye lens 2/1075 23/18639 0.0869565217391304 1.50770475227503 0.385983446883489 0.804963490617853 GO:0016493 C-C chemokine receptor activity 2/1075 23/18639 0.0869565217391304 1.50770475227503 0.385983446883489 0.804963490617853 GO:0043274 phospholipase binding 2/1075 23/18639 0.0869565217391304 1.50770475227503 0.385983446883489 0.804963490617853 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/1075 23/18639 0.0869565217391304 1.50770475227503 0.385983446883489 0.804963490617853 GO:0016922 nuclear receptor binding 9/1075 137/18639 0.0656934306569343 1.13903242233916 0.393158676323263 0.818300498934729 GO:0170055 lipid transmembrane transporter activity 4/1075 56/18639 0.0714285714285714 1.23847176079734 0.405641793251221 0.834716573841586 GO:0004806 triacylglycerol lipase activity 2/1075 24/18639 0.0833333333333333 1.44488372093023 0.406705504019997 0.834716573841586 GO:0015295 solute:proton symporter activity 2/1075 24/18639 0.0833333333333333 1.44488372093023 0.406705504019997 0.834716573841586 GO:0019957 C-C chemokine binding 2/1075 24/18639 0.0833333333333333 1.44488372093023 0.406705504019997 0.834716573841586 GO:0050431 transforming growth factor beta binding 2/1075 24/18639 0.0833333333333333 1.44488372093023 0.406705504019997 0.834716573841586 GO:0003713 transcription coactivator activity 16/1075 256/18639 0.0625 1.08366279069767 0.406855129733944 0.834716573841586 GO:0032451 demethylase activity 3/1075 40/18639 0.075 1.30039534883721 0.408269065564608 0.834716573841586 GO:0061791 GTPase motor activity 3/1075 40/18639 0.075 1.30039534883721 0.408269065564608 0.834716573841586 GO:1990606 membrane scission GTPase motor activity 3/1075 40/18639 0.075 1.30039534883721 0.408269065564608 0.834716573841586 GO:0070851 growth factor receptor binding 9/1075 139/18639 0.0647482014388489 1.12264346662205 0.409803753404162 0.834716573841586 GO:0043539 protein serine/threonine kinase activator activity 5/1075 73/18639 0.0684931506849315 1.18757566103855 0.413403827564381 0.834716573841586 GO:0003712 transcription coregulator activity 30/1075 495/18639 0.0606060606060606 1.0508245243129 0.416004999675719 0.834716573841586 GO:0042287 MHC protein binding 3/1075 41/18639 0.0731707317073171 1.26867838910947 0.423943629723796 0.834716573841586 GO:0140318 protein transporter activity 3/1075 41/18639 0.0731707317073171 1.26867838910947 0.423943629723796 0.834716573841586 GO:0031491 nucleosome binding 5/1075 74/18639 0.0675675675675676 1.17152734129478 0.424950958908817 0.834716573841586 GO:0005525 GTP binding 23/1075 378/18639 0.0608465608465608 1.05499446290144 0.426007283024006 0.834716573841586 GO:0000030 mannosyltransferase activity 2/1075 25/18639 0.08 1.38708837209302 0.427082133038033 0.834716573841586 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/1075 25/18639 0.08 1.38708837209302 0.427082133038033 0.834716573841586 GO:0017025 TBP-class protein binding 2/1075 25/18639 0.08 1.38708837209302 0.427082133038033 0.834716573841586 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/1075 25/18639 0.08 1.38708837209302 0.427082133038033 0.834716573841586 GO:0019707 protein-cysteine S-acyltransferase activity 2/1075 25/18639 0.08 1.38708837209302 0.427082133038033 0.834716573841586 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/1075 25/18639 0.08 1.38708837209302 0.427082133038033 0.834716573841586 GO:0008408 3'-5' exonuclease activity 4/1075 58/18639 0.0689655172413793 1.19576583801123 0.431941613037581 0.834716573841586 GO:0019003 GDP binding 5/1075 75/18639 0.0666666666666667 1.15590697674419 0.436454373669655 0.834716573841586 GO:0004402 histone acetyltransferase activity 3/1075 42/18639 0.0714285714285714 1.23847176079734 0.439472193409457 0.834716573841586 GO:0051879 Hsp90 protein binding 3/1075 42/18639 0.0714285714285714 1.23847176079734 0.439472193409457 0.834716573841586 GO:0004842 ubiquitin-protein transferase activity 27/1075 449/18639 0.0601336302895323 1.04263324182939 0.439553157616607 0.834716573841586 GO:0001637 G protein-coupled chemoattractant receptor activity 2/1075 26/18639 0.0769230769230769 1.33373881932021 0.44708423996502 0.834716573841586 GO:0004435 phosphatidylinositol phospholipase C activity 2/1075 26/18639 0.0769230769230769 1.33373881932021 0.44708423996502 0.834716573841586 GO:0004950 chemokine receptor activity 2/1075 26/18639 0.0769230769230769 1.33373881932021 0.44708423996502 0.834716573841586 GO:0008157 protein phosphatase 1 binding 2/1075 26/18639 0.0769230769230769 1.33373881932021 0.44708423996502 0.834716573841586 GO:0008198 ferrous iron binding 2/1075 26/18639 0.0769230769230769 1.33373881932021 0.44708423996502 0.834716573841586 GO:0052742 phosphatidylinositol kinase activity 2/1075 26/18639 0.0769230769230769 1.33373881932021 0.44708423996502 0.834716573841586 GO:0120014 phospholipid transfer activity 2/1075 26/18639 0.0769230769230769 1.33373881932021 0.44708423996502 0.834716573841586 GO:0000182 rDNA binding 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0004090 carbonyl reductase (NADPH) activity 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0004935 adrenergic receptor activity 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0004955 prostaglandin receptor activity 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0005528 FK506 binding 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0008401 retinoic acid 4-hydroxylase activity 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0015187 glycine transmembrane transporter activity 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0015643 toxic substance binding 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0016783 sulfurtransferase activity 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0030957 Tat protein binding 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0031720 haptoglobin binding 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0031996 thioesterase binding 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0035256 G protein-coupled glutamate receptor binding 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0043422 protein kinase B binding 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0051864 histone H3K36 demethylase activity 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0070513 death domain binding 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0140940 histone H2A methyltransferase activity 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:1905394 retromer complex binding 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:1990259 histone H2AQ104 methyltransferase activity 1/1075 10/18639 0.1 1.73386046511628 0.447993737914979 0.834716573841586 GO:0019001 guanyl nucleotide binding 24/1075 400/18639 0.06 1.04031627906977 0.450802874606973 0.836977372500381 GO:0032561 guanyl ribonucleotide binding 24/1075 400/18639 0.06 1.04031627906977 0.450802874606973 0.836977372500381 GO:0005245 voltage-gated calcium channel activity 3/1075 43/18639 0.0697674418604651 1.20967009194159 0.454837305122141 0.842975853486089 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4/1075 60/18639 0.0666666666666667 1.15590697674419 0.457914846646379 0.844564087767841 GO:0008083 growth factor activity 10/1075 162/18639 0.0617283950617284 1.0702842377261 0.459213745121857 0.844564087767841 GO:0004364 glutathione transferase activity 2/1075 27/18639 0.0740740740740741 1.28434108527132 0.466687228936132 0.844564087767841 GO:0005385 zinc ion transmembrane transporter activity 2/1075 27/18639 0.0740740740740741 1.28434108527132 0.466687228936132 0.844564087767841 GO:0008320 protein transmembrane transporter activity 2/1075 27/18639 0.0740740740740741 1.28434108527132 0.466687228936132 0.844564087767841 GO:0015293 symporter activity 9/1075 146/18639 0.0616438356164384 1.06881809493469 0.46785521274693 0.844564087767841 GO:0008276 protein methyltransferase activity 6/1075 95/18639 0.0631578947368421 1.09506976744186 0.470118542268741 0.844564087767841 GO:0019905 syntaxin binding 4/1075 61/18639 0.0655737704918033 1.13695768204346 0.470750667003248 0.844564087767841 GO:0016298 lipase activity 8/1075 130/18639 0.0615384615384615 1.06699105545617 0.477416349258442 0.844564087767841 GO:0004016 adenylate cyclase activity 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0004954 prostanoid receptor activity 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0005114 type II transforming growth factor beta receptor binding 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0005536 D-glucose binding 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0008199 ferric iron binding 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0008503 benzodiazepine receptor activity 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0008526 phosphatidylinositol transfer activity 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0010854 adenylate cyclase regulator activity 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0019107 myristoyltransferase activity 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0019864 IgG binding 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0032794 GTPase activating protein binding 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0043522 leucine zipper domain binding 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0047676 arachidonate-CoA ligase activity 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0048185 activin binding 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0070697 activin receptor binding 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0070990 snRNP binding 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0097493 structural molecule activity conferring elasticity 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/1075 11/18639 0.0909090909090909 1.57623678646934 0.479847660924341 0.844564087767841 GO:0008009 chemokine activity 3/1075 45/18639 0.0666666666666667 1.15590697674419 0.485014636472986 0.850881868796274 GO:0051959 dynein light intermediate chain binding 2/1075 28/18639 0.0714285714285714 1.23847176079734 0.485870580942772 0.850881868796274 GO:0097718 disordered domain specific binding 2/1075 28/18639 0.0714285714285714 1.23847176079734 0.485870580942772 0.850881868796274 GO:0005507 copper ion binding 4/1075 63/18639 0.0634920634920635 1.10086378737542 0.496069806839274 0.85166947211025 GO:0016755 aminoacyltransferase activity 29/1075 496/18639 0.0584677419354839 1.01374906226557 0.497385428389134 0.85166947211025 GO:0019787 ubiquitin-like protein transferase activity 28/1075 479/18639 0.058455114822547 1.01353012574647 0.498864801683799 0.85166947211025 GO:0008170 N-methyltransferase activity 6/1075 98/18639 0.0612244897959184 1.06154722354058 0.500500867855814 0.85166947211025 GO:0030971 receptor tyrosine kinase binding 5/1075 81/18639 0.0617283950617284 1.0702842377261 0.504100312481404 0.85166947211025 GO:0004181 metallocarboxypeptidase activity 2/1075 29/18639 0.0689655172413793 1.19576583801123 0.504617466137687 0.85166947211025 GO:0004629 phospholipase C activity 2/1075 29/18639 0.0689655172413793 1.19576583801123 0.504617466137687 0.85166947211025 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/1075 29/18639 0.0689655172413793 1.19576583801123 0.504617466137687 0.85166947211025 GO:0016417 S-acyltransferase activity 2/1075 29/18639 0.0689655172413793 1.19576583801123 0.504617466137687 0.85166947211025 GO:0035250 UDP-galactosyltransferase activity 2/1075 29/18639 0.0689655172413793 1.19576583801123 0.504617466137687 0.85166947211025 GO:0097472 cyclin-dependent protein kinase activity 2/1075 29/18639 0.0689655172413793 1.19576583801123 0.504617466137687 0.85166947211025 GO:0099604 ligand-gated calcium channel activity 2/1075 29/18639 0.0689655172413793 1.19576583801123 0.504617466137687 0.85166947211025 GO:0015294 solute:monoatomic cation symporter activity 7/1075 116/18639 0.0603448275862069 1.04629510825982 0.50668883037784 0.85166947211025 GO:0004859 phospholipase inhibitor activity 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0005247 voltage-gated chloride channel activity 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0005527 macrolide binding 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0015132 prostaglandin transmembrane transporter activity 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0015368 calcium:monoatomic cation antiporter activity 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0016801 hydrolase activity, acting on ether bonds 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0016803 ether hydrolase activity 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0016840 carbon-nitrogen lyase activity 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0035259 nuclear glucocorticoid receptor binding 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0036009 protein-glutamine N-methyltransferase activity 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0042301 phosphate ion binding 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0097371 MDM2/MDM4 family protein binding 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0097677 STAT family protein binding 1/1075 12/18639 0.0833333333333333 1.44488372093023 0.509865041453991 0.85166947211025 GO:0043495 protein-membrane adaptor activity 3/1075 47/18639 0.0638297872340425 1.1067194458189 0.514364358292473 0.856457479125086 GO:0061733 protein-lysine-acetyltransferase activity 3/1075 47/18639 0.0638297872340425 1.1067194458189 0.514364358292473 0.856457479125086 GO:0038024 cargo receptor activity 4/1075 65/18639 0.0615384615384615 1.06699105545617 0.520858567350582 0.861125890435149 GO:0001965 G-protein alpha-subunit binding 2/1075 30/18639 0.0666666666666667 1.15590697674419 0.522914387232783 0.861125890435149 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/1075 30/18639 0.0666666666666667 1.15590697674419 0.522914387232783 0.861125890435149 GO:0031210 phosphatidylcholine binding 2/1075 30/18639 0.0666666666666667 1.15590697674419 0.522914387232783 0.861125890435149 GO:0051721 protein phosphatase 2A binding 2/1075 30/18639 0.0666666666666667 1.15590697674419 0.522914387232783 0.861125890435149 GO:0070566 adenylyltransferase activity 2/1075 30/18639 0.0666666666666667 1.15590697674419 0.522914387232783 0.861125890435149 GO:0098918 structural constituent of synapse 2/1075 30/18639 0.0666666666666667 1.15590697674419 0.522914387232783 0.861125890435149 GO:0016879 ligase activity, forming carbon-nitrogen bonds 3/1075 48/18639 0.0625 1.08366279069767 0.528699847256988 0.867097933275296 GO:0140693 molecular condensate scaffold activity 3/1075 48/18639 0.0625 1.08366279069767 0.528699847256988 0.867097933275296 GO:0099094 ligand-gated monoatomic cation channel activity 8/1075 136/18639 0.0588235294117647 1.01991792065663 0.52902066472468 0.867097933275296 GO:0017154 semaphorin receptor activity 1/1075 13/18639 0.0769230769230769 1.33373881932021 0.53815167271168 0.867159915014673 GO:0035325 Toll-like receptor binding 1/1075 13/18639 0.0769230769230769 1.33373881932021 0.53815167271168 0.867159915014673 GO:0043560 insulin receptor substrate binding 1/1075 13/18639 0.0769230769230769 1.33373881932021 0.53815167271168 0.867159915014673 GO:0046975 histone H3K36 methyltransferase activity 1/1075 13/18639 0.0769230769230769 1.33373881932021 0.53815167271168 0.867159915014673 GO:0051011 microtubule minus-end binding 1/1075 13/18639 0.0769230769230769 1.33373881932021 0.53815167271168 0.867159915014673 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/1075 13/18639 0.0769230769230769 1.33373881932021 0.53815167271168 0.867159915014673 GO:0061459 L-arginine transmembrane transporter activity 1/1075 13/18639 0.0769230769230769 1.33373881932021 0.53815167271168 0.867159915014673 GO:0071714 icosanoid transmembrane transporter activity 1/1075 13/18639 0.0769230769230769 1.33373881932021 0.53815167271168 0.867159915014673 GO:0071837 HMG box domain binding 1/1075 13/18639 0.0769230769230769 1.33373881932021 0.53815167271168 0.867159915014673 GO:0097157 pre-mRNA intronic binding 1/1075 13/18639 0.0769230769230769 1.33373881932021 0.53815167271168 0.867159915014673 GO:1901338 catecholamine binding 1/1075 13/18639 0.0769230769230769 1.33373881932021 0.53815167271168 0.867159915014673 GO:0015171 amino acid transmembrane transporter activity 6/1075 102/18639 0.0588235294117647 1.01991792065663 0.540005110341098 0.868679392696931 GO:0070273 phosphatidylinositol-4-phosphate binding 2/1075 31/18639 0.0645161290322581 1.11861965491373 0.540750851697899 0.868679392696931 GO:0005244 voltage-gated monoatomic ion channel activity 10/1075 173/18639 0.0578034682080925 1.00223148272617 0.543491757426584 0.871747482477808 GO:0008378 galactosyltransferase activity 2/1075 32/18639 0.0625 1.08366279069767 0.558119070629307 0.886950321531027 GO:0070717 poly-purine tract binding 2/1075 32/18639 0.0625 1.08366279069767 0.558119070629307 0.886950321531027 GO:0120015 sterol transfer activity 2/1075 32/18639 0.0625 1.08366279069767 0.558119070629307 0.886950321531027 GO:0022832 voltage-gated channel activity 10/1075 175/18639 0.0571428571428571 0.990777408637874 0.558325411409662 0.886950321531027 GO:0005161 platelet-derived growth factor receptor binding 1/1075 14/18639 0.0714285714285714 1.23847176079734 0.564807259087442 0.886950321531027 GO:0005313 L-glutamate transmembrane transporter activity 1/1075 14/18639 0.0714285714285714 1.23847176079734 0.564807259087442 0.886950321531027 GO:0005344 oxygen carrier activity 1/1075 14/18639 0.0714285714285714 1.23847176079734 0.564807259087442 0.886950321531027 GO:0005545 1-phosphatidylinositol binding 1/1075 14/18639 0.0714285714285714 1.23847176079734 0.564807259087442 0.886950321531027 GO:0008494 translation activator activity 1/1075 14/18639 0.0714285714285714 1.23847176079734 0.564807259087442 0.886950321531027 GO:0015386 potassium:proton antiporter activity 1/1075 14/18639 0.0714285714285714 1.23847176079734 0.564807259087442 0.886950321531027 GO:0046030 inositol trisphosphate phosphatase activity 1/1075 14/18639 0.0714285714285714 1.23847176079734 0.564807259087442 0.886950321531027 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/1075 14/18639 0.0714285714285714 1.23847176079734 0.564807259087442 0.886950321531027 GO:0061665 SUMO ligase activity 1/1075 14/18639 0.0714285714285714 1.23847176079734 0.564807259087442 0.886950321531027 GO:1901612 cardiolipin binding 1/1075 14/18639 0.0714285714285714 1.23847176079734 0.564807259087442 0.886950321531027 GO:0061630 ubiquitin protein ligase activity 20/1075 353/18639 0.056657223796034 0.982357204031886 0.565986462914425 0.887473541998852 GO:0002039 p53 binding 4/1075 69/18639 0.0579710144927536 1.00513650151668 0.568599591178815 0.890240255442651 GO:0005272 sodium channel activity 3/1075 51/18639 0.0588235294117647 1.01991792065663 0.570238379251326 0.891396037393947 GO:0061659 ubiquitin-like protein ligase activity 21/1075 372/18639 0.0564516129032258 0.978792198049512 0.572898617527722 0.891396037393947 GO:0004197 cysteine-type endopeptidase activity 5/1075 88/18639 0.0568181818181818 0.98514799154334 0.578596846257405 0.891396037393947 GO:0016782 transferase activity, transferring sulphur-containing groups 4/1075 70/18639 0.0571428571428571 0.990777408637874 0.580115246046683 0.891396037393947 GO:0004089 carbonate dehydratase activity 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0004129 cytochrome-c oxidase activity 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0004467 long-chain fatty acid-CoA ligase activity 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0004559 alpha-mannosidase activity 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0004953 icosanoid receptor activity 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0005041 low-density lipoprotein particle receptor activity 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0008242 omega peptidase activity 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0015929 hexosaminidase activity 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0016846 carbon-sulfur lyase activity 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0017081 chloride channel regulator activity 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0030553 cGMP binding 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0048531 beta-1,3-galactosyltransferase activity 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0050700 CARD domain binding 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0050780 dopamine receptor binding 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0061578 K63-linked deubiquitinase activity 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0140776 protein-containing complex destabilizing activity 1/1075 15/18639 0.0666666666666667 1.15590697674419 0.589925766281052 0.891396037393947 GO:0019825 oxygen binding 2/1075 34/18639 0.0588235294117647 1.01991792065663 0.591431498595031 0.891396037393947 GO:0090482 vitamin transmembrane transporter activity 2/1075 34/18639 0.0588235294117647 1.01991792065663 0.591431498595031 0.891396037393947 GO:0017046 peptide hormone binding 3/1075 53/18639 0.0566037735849057 0.981430451952611 0.596637160259279 0.895218279733049 GO:0034212 protein N-acetyltransferase activity 3/1075 53/18639 0.0566037735849057 0.981430451952611 0.596637160259279 0.895218279733049 GO:0046873 metal ion transmembrane transporter activity 25/1075 450/18639 0.0555555555555556 0.963255813953488 0.606789602149497 0.895218279733049 GO:0043015 gamma-tubulin binding 2/1075 35/18639 0.0571428571428571 0.990777408637874 0.60737127248412 0.895218279733049 GO:0140566 histone reader activity 2/1075 35/18639 0.0571428571428571 0.990777408637874 0.60737127248412 0.895218279733049 GO:0015081 sodium ion transmembrane transporter activity 9/1075 164/18639 0.0548780487804878 0.951508791832104 0.609255947235344 0.895218279733049 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 7/1075 128/18639 0.0546875 0.948204941860465 0.612000782623796 0.895218279733049 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0005521 lamin binding 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0008142 oxysterol binding 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0015378 sodium:chloride symporter activity 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0015385 sodium:proton antiporter activity 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0015923 mannosidase activity 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0022841 potassium ion leak channel activity 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0030275 LRR domain binding 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0034450 ubiquitin-ubiquitin ligase activity 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0055102 lipase inhibitor activity 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0070411 I-SMAD binding 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0097027 ubiquitin-protein transferase activator activity 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/1075 16/18639 0.0625 1.08366279069767 0.613595751313691 0.895218279733049 GO:0008374 O-acyltransferase activity 3/1075 55/18639 0.0545454545454545 0.945742071881607 0.621953659312196 0.90492011903109 GO:0016409 palmitoyltransferase activity 2/1075 36/18639 0.0555555555555556 0.963255813953488 0.622833485167252 0.90492011903109 GO:0055106 ubiquitin-protein transferase regulator activity 2/1075 36/18639 0.0555555555555556 0.963255813953488 0.622833485167252 0.90492011903109 GO:0016798 hydrolase activity, acting on glycosyl bonds 7/1075 130/18639 0.0538461538461538 0.93361717352415 0.628351862897024 0.90880082640853 GO:0015078 proton transmembrane transporter activity 10/1075 185/18639 0.0540540540540541 0.937221873035827 0.629281991308116 0.90880082640853 GO:0003725 double-stranded RNA binding 4/1075 75/18639 0.0533333333333333 0.924725581395349 0.634940129208871 0.90880082640853 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/1075 17/18639 0.0588235294117647 1.01991792065663 0.635900673578514 0.90880082640853 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/1075 17/18639 0.0588235294117647 1.01991792065663 0.635900673578514 0.90880082640853 GO:0005092 GDP-dissociation inhibitor activity 1/1075 17/18639 0.0588235294117647 1.01991792065663 0.635900673578514 0.90880082640853 GO:0008429 phosphatidylethanolamine binding 1/1075 17/18639 0.0588235294117647 1.01991792065663 0.635900673578514 0.90880082640853 GO:0008569 minus-end-directed microtubule motor activity 1/1075 17/18639 0.0588235294117647 1.01991792065663 0.635900673578514 0.90880082640853 GO:0009881 photoreceptor activity 1/1075 17/18639 0.0588235294117647 1.01991792065663 0.635900673578514 0.90880082640853 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/1075 17/18639 0.0588235294117647 1.01991792065663 0.635900673578514 0.90880082640853 GO:0032183 SUMO binding 1/1075 17/18639 0.0588235294117647 1.01991792065663 0.635900673578514 0.90880082640853 GO:0046965 nuclear retinoid X receptor binding 1/1075 17/18639 0.0588235294117647 1.01991792065663 0.635900673578514 0.90880082640853 GO:0016410 N-acyltransferase activity 5/1075 94/18639 0.0531914893617021 0.922266204849085 0.637409729524477 0.909718103770308 GO:0005179 hormone activity 7/1075 132/18639 0.053030303030303 0.919471458773784 0.644309511772407 0.917587520947404 GO:0004601 peroxidase activity 3/1075 57/18639 0.0526315789473684 0.912558139534884 0.646162793719088 0.917587520947404 GO:0042887 amide transmembrane transporter activity 2/1075 38/18639 0.0526315789473684 0.912558139534884 0.652334640284682 0.917587520947404 GO:0000400 four-way junction DNA binding 1/1075 18/18639 0.0555555555555556 0.963255813953488 0.65691918801859 0.917587520947404 GO:0008308 voltage-gated monoatomic anion channel activity 1/1075 18/18639 0.0555555555555556 0.963255813953488 0.65691918801859 0.917587520947404 GO:0008525 phosphatidylcholine transporter activity 1/1075 18/18639 0.0555555555555556 0.963255813953488 0.65691918801859 0.917587520947404 GO:0015280 ligand-gated sodium channel activity 1/1075 18/18639 0.0555555555555556 0.963255813953488 0.65691918801859 0.917587520947404 GO:0015373 monoatomic anion:sodium symporter activity 1/1075 18/18639 0.0555555555555556 0.963255813953488 0.65691918801859 0.917587520947404 GO:0017075 syntaxin-1 binding 1/1075 18/18639 0.0555555555555556 0.963255813953488 0.65691918801859 0.917587520947404 GO:0017128 phospholipid scramblase activity 1/1075 18/18639 0.0555555555555556 0.963255813953488 0.65691918801859 0.917587520947404 GO:0022851 GABA-gated chloride ion channel activity 1/1075 18/18639 0.0555555555555556 0.963255813953488 0.65691918801859 0.917587520947404 GO:0030228 lipoprotein particle receptor activity 1/1075 18/18639 0.0555555555555556 0.963255813953488 0.65691918801859 0.917587520947404 GO:0032393 MHC class I receptor activity 1/1075 18/18639 0.0555555555555556 0.963255813953488 0.65691918801859 0.917587520947404 GO:0034185 apolipoprotein binding 1/1075 18/18639 0.0555555555555556 0.963255813953488 0.65691918801859 0.917587520947404 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/1075 18/18639 0.0555555555555556 0.963255813953488 0.65691918801859 0.917587520947404 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/1075 18/18639 0.0555555555555556 0.963255813953488 0.65691918801859 0.917587520947404 GO:0000217 DNA secondary structure binding 2/1075 39/18639 0.0512820512820513 0.889159212880143 0.666381514639077 0.919878064911414 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/1075 39/18639 0.0512820512820513 0.889159212880143 0.666381514639077 0.919878064911414 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/1075 59/18639 0.0508474576271186 0.881623965313362 0.669251480125621 0.919878064911414 GO:0070063 RNA polymerase binding 3/1075 59/18639 0.0508474576271186 0.881623965313362 0.669251480125621 0.919878064911414 GO:0005506 iron ion binding 8/1075 154/18639 0.051948051948052 0.90070673512534 0.669766353413488 0.919878064911414 GO:0015370 solute:sodium symporter activity 4/1075 79/18639 0.0506329113924051 0.877904032970268 0.675314535636031 0.919878064911414 GO:0004890 GABA-A receptor activity 1/1075 19/18639 0.0526315789473684 0.912558139534884 0.676725421458255 0.919878064911414 GO:0005229 intracellularly calcium-gated chloride channel activity 1/1075 19/18639 0.0526315789473684 0.912558139534884 0.676725421458255 0.919878064911414 GO:0008574 plus-end-directed microtubule motor activity 1/1075 19/18639 0.0526315789473684 0.912558139534884 0.676725421458255 0.919878064911414 GO:0015245 fatty acid transmembrane transporter activity 1/1075 19/18639 0.0526315789473684 0.912558139534884 0.676725421458255 0.919878064911414 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/1075 19/18639 0.0526315789473684 0.912558139534884 0.676725421458255 0.919878064911414 GO:0022840 leak channel activity 1/1075 19/18639 0.0526315789473684 0.912558139534884 0.676725421458255 0.919878064911414 GO:0022842 narrow pore channel activity 1/1075 19/18639 0.0526315789473684 0.912558139534884 0.676725421458255 0.919878064911414 GO:0034987 immunoglobulin receptor binding 1/1075 19/18639 0.0526315789473684 0.912558139534884 0.676725421458255 0.919878064911414 GO:0046624 sphingolipid transporter activity 1/1075 19/18639 0.0526315789473684 0.912558139534884 0.676725421458255 0.919878064911414 GO:0070003 threonine-type peptidase activity 1/1075 19/18639 0.0526315789473684 0.912558139534884 0.676725421458255 0.919878064911414 GO:0141147 intracellularly calcium-gated channel activity 1/1075 19/18639 0.0526315789473684 0.912558139534884 0.676725421458255 0.919878064911414 GO:1990380 K48-linked deubiquitinase activity 1/1075 19/18639 0.0526315789473684 0.912558139534884 0.676725421458255 0.919878064911414 GO:0015036 disulfide oxidoreductase activity 2/1075 40/18639 0.05 0.86693023255814 0.679966380379839 0.919878064911414 GO:0050997 quaternary ammonium group binding 2/1075 40/18639 0.05 0.86693023255814 0.679966380379839 0.919878064911414 GO:0071855 neuropeptide receptor binding 2/1075 40/18639 0.05 0.86693023255814 0.679966380379839 0.919878064911414 GO:0071949 FAD binding 2/1075 40/18639 0.05 0.86693023255814 0.679966380379839 0.919878064911414 GO:0016757 glycosyltransferase activity 14/1075 267/18639 0.052434456928839 0.909140318787562 0.681916565649159 0.919878064911414 GO:0005261 monoatomic cation channel activity 18/1075 341/18639 0.0527859237536657 0.915234263111232 0.68537686111012 0.919878064911414 GO:0015291 secondary active transmembrane transporter activity 15/1075 287/18639 0.0522648083623693 0.906198849363909 0.69027741495952 0.919878064911414 GO:0001727 lipid kinase activity 2/1075 41/18639 0.0487804878048781 0.845785592739648 0.693095752208354 0.919878064911414 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/1075 41/18639 0.0487804878048781 0.845785592739648 0.693095752208354 0.919878064911414 GO:0140828 metal cation:monoatomic cation antiporter activity 2/1075 41/18639 0.0487804878048781 0.845785592739648 0.693095752208354 0.919878064911414 GO:0033192 calmodulin-dependent protein phosphatase activity 4/1075 81/18639 0.0493827160493827 0.856227390180878 0.694301241667049 0.919878064911414 GO:0140791 histone H2AXS140 phosphatase activity 4/1075 81/18639 0.0493827160493827 0.856227390180878 0.694301241667049 0.919878064911414 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 4/1075 81/18639 0.0493827160493827 0.856227390180878 0.694301241667049 0.919878064911414 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 4/1075 81/18639 0.0493827160493827 0.856227390180878 0.694301241667049 0.919878064911414 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 4/1075 81/18639 0.0493827160493827 0.856227390180878 0.694301241667049 0.919878064911414 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 4/1075 81/18639 0.0493827160493827 0.856227390180878 0.694301241667049 0.919878064911414 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 4/1075 81/18639 0.0493827160493827 0.856227390180878 0.694301241667049 0.919878064911414 GO:1990439 MAP kinase serine/threonine phosphatase activity 4/1075 81/18639 0.0493827160493827 0.856227390180878 0.694301241667049 0.919878064911414 GO:0005326 neurotransmitter transmembrane transporter activity 1/1075 20/18639 0.05 0.86693023255814 0.695389233055053 0.919878064911414 GO:0016004 phospholipase activator activity 1/1075 20/18639 0.05 0.86693023255814 0.695389233055053 0.919878064911414 GO:0042288 MHC class I protein binding 1/1075 20/18639 0.05 0.86693023255814 0.695389233055053 0.919878064911414 GO:0043024 ribosomal small subunit binding 1/1075 20/18639 0.05 0.86693023255814 0.695389233055053 0.919878064911414 GO:0052745 inositol phosphate phosphatase activity 1/1075 20/18639 0.05 0.86693023255814 0.695389233055053 0.919878064911414 GO:0140664 ATP-dependent DNA damage sensor activity 1/1075 20/18639 0.05 0.86693023255814 0.695389233055053 0.919878064911414 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 4/1075 82/18639 0.0487804878048781 0.845785592739648 0.703492228893981 0.928255783785895 GO:0033549 MAP kinase phosphatase activity 4/1075 82/18639 0.0487804878048781 0.845785592739648 0.703492228893981 0.928255783785895 GO:0019894 kinesin binding 2/1075 42/18639 0.0476190476190476 0.825647840531561 0.705776930148299 0.928933500283018 GO:0043175 RNA polymerase core enzyme binding 2/1075 42/18639 0.0476190476190476 0.825647840531561 0.705776930148299 0.928933500283018 GO:0015079 potassium ion transmembrane transporter activity 8/1075 160/18639 0.05 0.86693023255814 0.710545986059403 0.929083610327194 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 6/1075 122/18639 0.0491803278688525 0.852718261532596 0.712397937879121 0.929083610327194 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 4/1075 83/18639 0.0481927710843374 0.835595404875315 0.712481648027033 0.929083610327194 GO:0008373 sialyltransferase activity 1/1075 21/18639 0.0476190476190476 0.825647840531561 0.712976459783976 0.929083610327194 GO:0009975 cyclase activity 1/1075 21/18639 0.0476190476190476 0.825647840531561 0.712976459783976 0.929083610327194 GO:0019200 carbohydrate kinase activity 1/1075 21/18639 0.0476190476190476 0.825647840531561 0.712976459783976 0.929083610327194 GO:0035613 RNA stem-loop binding 1/1075 21/18639 0.0476190476190476 0.825647840531561 0.712976459783976 0.929083610327194 GO:0036122 BMP binding 1/1075 21/18639 0.0476190476190476 0.825647840531561 0.712976459783976 0.929083610327194 GO:0004722 protein serine/threonine phosphatase activity 5/1075 103/18639 0.0485436893203883 0.841679837435087 0.715497439057831 0.931211927508269 GO:0008375 acetylglucosaminyltransferase activity 2/1075 43/18639 0.0465116279069767 0.80644672796106 0.718017887466648 0.933334279990723 GO:0017018 myosin phosphatase activity 4/1075 84/18639 0.0476190476190476 0.825647840531561 0.721269869804313 0.936401105723669 GO:0022843 voltage-gated monoatomic cation channel activity 7/1075 143/18639 0.048951048951049 0.848742885021955 0.724546190771393 0.939491908676379 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/1075 22/18639 0.0454545454545455 0.788118393234672 0.729549147813422 0.941683518039215 GO:0061133 endopeptidase activator activity 1/1075 22/18639 0.0454545454545455 0.788118393234672 0.729549147813422 0.941683518039215 GO:0003954 NADH dehydrogenase activity 2/1075 44/18639 0.0454545454545455 0.788118393234672 0.729827168890259 0.941683518039215 GO:0019205 nucleobase-containing compound kinase activity 2/1075 44/18639 0.0454545454545455 0.788118393234672 0.729827168890259 0.941683518039215 GO:0008194 UDP-glycosyltransferase activity 7/1075 145/18639 0.0482758620689655 0.837036086607859 0.737710086775126 0.950078217675273 GO:0004497 monooxygenase activity 5/1075 106/18639 0.0471698113207547 0.817858709960509 0.738698256870815 0.950078217675273 GO:0046915 transition metal ion transmembrane transporter activity 2/1075 45/18639 0.0444444444444444 0.770604651162791 0.741213798305016 0.950078217675273 GO:0051539 4 iron, 4 sulfur cluster binding 2/1075 45/18639 0.0444444444444444 0.770604651162791 0.741213798305016 0.950078217675273 GO:0016849 phosphorus-oxygen lyase activity 1/1075 23/18639 0.0434782608695652 0.753852376137513 0.745165770582965 0.950078217675273 GO:0016917 GABA receptor activity 1/1075 23/18639 0.0434782608695652 0.753852376137513 0.745165770582965 0.950078217675273 GO:0031681 G-protein beta-subunit binding 1/1075 23/18639 0.0434782608695652 0.753852376137513 0.745165770582965 0.950078217675273 GO:0099186 structural constituent of postsynapse 1/1075 23/18639 0.0434782608695652 0.753852376137513 0.745165770582965 0.950078217675273 GO:0140103 catalytic activity, acting on a glycoprotein 1/1075 23/18639 0.0434782608695652 0.753852376137513 0.745165770582965 0.950078217675273 GO:0003714 transcription corepressor activity 10/1075 204/18639 0.0490196078431373 0.849931600547196 0.745542315446268 0.950078217675273 GO:0042826 histone deacetylase binding 6/1075 127/18639 0.047244094488189 0.819146676432888 0.747730110684772 0.950078217675273 GO:0015276 ligand-gated monoatomic ion channel activity 9/1075 186/18639 0.0483870967741935 0.838964741185296 0.751949710978271 0.950078217675273 GO:0004180 carboxypeptidase activity 2/1075 46/18639 0.0434782608695652 0.753852376137513 0.752187195183918 0.950078217675273 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 3/1075 68/18639 0.0441176470588235 0.764938440492476 0.759409359175214 0.950078217675273 GO:0005315 phosphate transmembrane transporter activity 1/1075 24/18639 0.0416666666666667 0.722441860465116 0.759881434346572 0.950078217675273 GO:0005540 hyaluronic acid binding 1/1075 24/18639 0.0416666666666667 0.722441860465116 0.759881434346572 0.950078217675273 GO:0015149 hexose transmembrane transporter activity 1/1075 24/18639 0.0416666666666667 0.722441860465116 0.759881434346572 0.950078217675273 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/1075 24/18639 0.0416666666666667 0.722441860465116 0.759881434346572 0.950078217675273 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/1075 24/18639 0.0416666666666667 0.722441860465116 0.759881434346572 0.950078217675273 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/1075 24/18639 0.0416666666666667 0.722441860465116 0.759881434346572 0.950078217675273 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/1075 24/18639 0.0416666666666667 0.722441860465116 0.759881434346572 0.950078217675273 GO:0055056 D-glucose transmembrane transporter activity 1/1075 24/18639 0.0416666666666667 0.722441860465116 0.759881434346572 0.950078217675273 GO:0060229 lipase activator activity 1/1075 24/18639 0.0416666666666667 0.722441860465116 0.759881434346572 0.950078217675273 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/1075 24/18639 0.0416666666666667 0.722441860465116 0.759881434346572 0.950078217675273 GO:0070840 dynein complex binding 1/1075 24/18639 0.0416666666666667 0.722441860465116 0.759881434346572 0.950078217675273 GO:0140612 DNA damage sensor activity 1/1075 24/18639 0.0416666666666667 0.722441860465116 0.759881434346572 0.950078217675273 GO:0099095 ligand-gated monoatomic anion channel activity 2/1075 47/18639 0.0425531914893617 0.737812963879268 0.76275709904576 0.950423568412468 GO:0022834 ligand-gated channel activity 9/1075 188/18639 0.0478723404255319 0.830039584364176 0.762906949199004 0.950423568412468 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 6/1075 130/18639 0.0461538461538462 0.800243291592129 0.767366800384526 0.950423568412468 GO:0008080 N-acetyltransferase activity 3/1075 69/18639 0.0434782608695652 0.753852376137513 0.768082530447777 0.950423568412468 GO:0005251 delayed rectifier potassium channel activity 1/1075 25/18639 0.04 0.693544186046512 0.773748071901094 0.950423568412468 GO:0008139 nuclear localization sequence binding 1/1075 25/18639 0.04 0.693544186046512 0.773748071901094 0.950423568412468 GO:0015645 fatty acid ligase activity 1/1075 25/18639 0.04 0.693544186046512 0.773748071901094 0.950423568412468 GO:0015662 P-type ion transporter activity 1/1075 25/18639 0.04 0.693544186046512 0.773748071901094 0.950423568412468 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/1075 25/18639 0.04 0.693544186046512 0.773748071901094 0.950423568412468 GO:0017056 structural constituent of nuclear pore 1/1075 25/18639 0.04 0.693544186046512 0.773748071901094 0.950423568412468 GO:0042974 nuclear retinoic acid receptor binding 1/1075 25/18639 0.04 0.693544186046512 0.773748071901094 0.950423568412468 GO:0047617 fatty acyl-CoA hydrolase activity 1/1075 25/18639 0.04 0.693544186046512 0.773748071901094 0.950423568412468 GO:0120020 cholesterol transfer activity 1/1075 25/18639 0.04 0.693544186046512 0.773748071901094 0.950423568412468 GO:0120515 fatty acid-CoA ligase activity 1/1075 25/18639 0.04 0.693544186046512 0.773748071901094 0.950423568412468 GO:0140358 P-type transmembrane transporter activity 1/1075 25/18639 0.04 0.693544186046512 0.773748071901094 0.950423568412468 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 11/1075 229/18639 0.0480349344978166 0.832858738702143 0.775108942348816 0.950981614647845 GO:0042277 peptide binding 12/1075 249/18639 0.0481927710843374 0.835595404875315 0.778746070970919 0.954183285332122 GO:0052689 carboxylic ester hydrolase activity 4/1075 92/18639 0.0434782608695652 0.753852376137513 0.784458611085305 0.954183285332122 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/1075 26/18639 0.0384615384615385 0.666869409660107 0.786814625178537 0.954183285332122 GO:0008143 poly(A) binding 1/1075 26/18639 0.0384615384615385 0.666869409660107 0.786814625178537 0.954183285332122 GO:0015145 monosaccharide transmembrane transporter activity 1/1075 26/18639 0.0384615384615385 0.666869409660107 0.786814625178537 0.954183285332122 GO:0016289 acyl-CoA hydrolase activity 1/1075 26/18639 0.0384615384615385 0.666869409660107 0.786814625178537 0.954183285332122 GO:0030247 polysaccharide binding 1/1075 26/18639 0.0384615384615385 0.666869409660107 0.786814625178537 0.954183285332122 GO:0034237 protein kinase A regulatory subunit binding 1/1075 26/18639 0.0384615384615385 0.666869409660107 0.786814625178537 0.954183285332122 GO:0051139 metal cation:proton antiporter activity 1/1075 26/18639 0.0384615384615385 0.666869409660107 0.786814625178537 0.954183285332122 GO:0070412 R-SMAD binding 1/1075 26/18639 0.0384615384615385 0.666869409660107 0.786814625178537 0.954183285332122 GO:0001671 ATPase activator activity 1/1075 27/18639 0.037037037037037 0.642170542635659 0.799127217341707 0.960234193575545 GO:0005044 scavenger receptor activity 1/1075 27/18639 0.037037037037037 0.642170542635659 0.799127217341707 0.960234193575545 GO:0008266 poly(U) RNA binding 1/1075 27/18639 0.037037037037037 0.642170542635659 0.799127217341707 0.960234193575545 GO:0008395 steroid hydroxylase activity 1/1075 27/18639 0.037037037037037 0.642170542635659 0.799127217341707 0.960234193575545 GO:0015252 proton channel activity 1/1075 27/18639 0.037037037037037 0.642170542635659 0.799127217341707 0.960234193575545 GO:0016405 CoA-ligase activity 1/1075 27/18639 0.037037037037037 0.642170542635659 0.799127217341707 0.960234193575545 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/1075 27/18639 0.037037037037037 0.642170542635659 0.799127217341707 0.960234193575545 GO:0035255 ionotropic glutamate receptor binding 1/1075 27/18639 0.037037037037037 0.642170542635659 0.799127217341707 0.960234193575545 GO:0005048 signal sequence binding 2/1075 51/18639 0.0392156862745098 0.679945280437756 0.801204145040528 0.960529312168587 GO:0016597 amino acid binding 2/1075 51/18639 0.0392156862745098 0.679945280437756 0.801204145040528 0.960529312168587 GO:0016758 hexosyltransferase activity 9/1075 197/18639 0.0456852791878173 0.792118994215559 0.807961568295798 0.96423475217736 GO:0005242 inward rectifier potassium channel activity 1/1075 28/18639 0.0357142857142857 0.619235880398671 0.810729314986112 0.96423475217736 GO:0019789 SUMO transferase activity 1/1075 28/18639 0.0357142857142857 0.619235880398671 0.810729314986112 0.96423475217736 GO:0046966 nuclear thyroid hormone receptor binding 1/1075 28/18639 0.0357142857142857 0.619235880398671 0.810729314986112 0.96423475217736 GO:0050698 proteoglycan sulfotransferase activity 1/1075 28/18639 0.0357142857142857 0.619235880398671 0.810729314986112 0.96423475217736 GO:0051019 mitogen-activated protein kinase binding 1/1075 28/18639 0.0357142857142857 0.619235880398671 0.810729314986112 0.96423475217736 GO:0051119 sugar transmembrane transporter activity 1/1075 28/18639 0.0357142857142857 0.619235880398671 0.810729314986112 0.96423475217736 GO:0022853 active monoatomic ion transmembrane transporter activity 5/1075 118/18639 0.0423728813559322 0.734686637761135 0.817590623325801 0.969907879617721 GO:0008146 sulfotransferase activity 2/1075 53/18639 0.0377358490566038 0.654286967968407 0.818273091955847 0.969907879617721 GO:0140296 general transcription initiation factor binding 2/1075 53/18639 0.0377358490566038 0.654286967968407 0.818273091955847 0.969907879617721 GO:0140767 enzyme-substrate adaptor activity 6/1075 139/18639 0.0431654676258993 0.748428977748034 0.819418078676437 0.970168808726391 GO:0106222 lncRNA binding 1/1075 29/18639 0.0344827586206897 0.597882919005613 0.821661881016413 0.971728650717268 GO:0005249 voltage-gated potassium channel activity 4/1075 98/18639 0.0408163265306122 0.707698149027053 0.823931374822606 0.971742584723781 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/1075 54/18639 0.037037037037037 0.642170542635659 0.826305419993911 0.971742584723781 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/1075 54/18639 0.037037037037037 0.642170542635659 0.826305419993911 0.971742584723781 GO:0050661 NADP binding 2/1075 54/18639 0.037037037037037 0.642170542635659 0.826305419993911 0.971742584723781 GO:0140463 chromatin-protein adaptor activity 2/1075 54/18639 0.037037037037037 0.642170542635659 0.826305419993911 0.971742584723781 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/1075 30/18639 0.0333333333333333 0.577953488372093 0.831963518733089 0.974028717802467 GO:0008187 poly-pyrimidine tract binding 1/1075 30/18639 0.0333333333333333 0.577953488372093 0.831963518733089 0.974028717802467 GO:0033612 receptor serine/threonine kinase binding 1/1075 30/18639 0.0333333333333333 0.577953488372093 0.831963518733089 0.974028717802467 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/1075 30/18639 0.0333333333333333 0.577953488372093 0.831963518733089 0.974028717802467 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/1075 31/18639 0.032258064516129 0.559309827456864 0.841670607634262 0.982105080543205 GO:0016878 acid-thiol ligase activity 1/1075 31/18639 0.032258064516129 0.559309827456864 0.841670607634262 0.982105080543205 GO:0072349 modified amino acid transmembrane transporter activity 1/1075 31/18639 0.032258064516129 0.559309827456864 0.841670607634262 0.982105080543205 GO:0000049 tRNA binding 3/1075 80/18639 0.0375 0.650197674418605 0.847518656844375 0.987830078921943 GO:0005267 potassium channel activity 5/1075 124/18639 0.0403225806451613 0.69913728432108 0.849197942022777 0.988688835939948 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/1075 58/18639 0.0344827586206897 0.597882919005613 0.855327331929259 0.993707958276507 GO:0046943 carboxylic acid transmembrane transporter activity 8/1075 188/18639 0.0425531914893617 0.737812963879268 0.855403514131254 0.993707958276507 GO:0005342 organic acid transmembrane transporter activity 8/1075 189/18639 0.0423280423280423 0.73390919158361 0.859255341557176 0.994595454714651 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/1075 33/18639 0.0303030303030303 0.525412262156448 0.859436298568058 0.994595454714651 GO:0140416 transcription regulator inhibitor activity 1/1075 33/18639 0.0303030303030303 0.525412262156448 0.859436298568058 0.994595454714651 GO:0015459 potassium channel regulator activity 2/1075 59/18639 0.0338983050847458 0.587749310208908 0.861856309185527 0.994595454714651 GO:0031593 polyubiquitin modification-dependent protein binding 2/1075 59/18639 0.0338983050847458 0.587749310208908 0.861856309185527 0.994595454714651 GO:0036002 pre-mRNA binding 2/1075 59/18639 0.0338983050847458 0.587749310208908 0.861856309185527 0.994595454714651 GO:0015020 glucuronosyltransferase activity 1/1075 34/18639 0.0294117647058824 0.509958960328317 0.867557656142998 0.996788588492886 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/1075 34/18639 0.0294117647058824 0.509958960328317 0.867557656142998 0.996788588492886 GO:0016831 carboxy-lyase activity 1/1075 34/18639 0.0294117647058824 0.509958960328317 0.867557656142998 0.996788588492886 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/1075 34/18639 0.0294117647058824 0.509958960328317 0.867557656142998 0.996788588492886 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/1075 61/18639 0.0327868852459016 0.568478841021731 0.874110820332348 0.999999999684511 GO:0016836 hydro-lyase activity 2/1075 61/18639 0.0327868852459016 0.568478841021731 0.874110820332348 0.999999999684511 GO:0061631 ubiquitin conjugating enzyme activity 1/1075 35/18639 0.0285714285714286 0.495388704318937 0.875210196838847 0.999999999684511 GO:0046906 tetrapyrrole binding 6/1075 152/18639 0.0394736842105263 0.684418604651163 0.877819373834539 0.999999999684511 GO:0050660 flavin adenine dinucleotide binding 3/1075 86/18639 0.0348837209302326 0.604835045970795 0.879979942727076 0.999999999684511 GO:0031072 heat shock protein binding 5/1075 131/18639 0.0381679389312977 0.661778803479496 0.880192189435768 0.999999999684511 GO:0000993 RNA polymerase II complex binding 1/1075 36/18639 0.0277777777777778 0.481627906976744 0.882420960029465 0.999999999684511 GO:0004033 aldo-keto reductase (NADPH) activity 1/1075 36/18639 0.0277777777777778 0.481627906976744 0.882420960029465 0.999999999684511 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/1075 36/18639 0.0277777777777778 0.481627906976744 0.882420960029465 0.999999999684511 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/1075 36/18639 0.0277777777777778 0.481627906976744 0.882420960029465 0.999999999684511 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/1075 36/18639 0.0277777777777778 0.481627906976744 0.882420960029465 0.999999999684511 GO:0022836 gated channel activity 14/1075 318/18639 0.0440251572327044 0.763334795963142 0.883265234439559 0.999999999684511 GO:0022804 active transmembrane transporter activity 21/1075 457/18639 0.0459518599562363 0.79674113276678 0.885827623372132 0.999999999684511 GO:0016651 oxidoreductase activity, acting on NAD(P)H 3/1075 88/18639 0.0340909090909091 0.591088794926004 0.889349008111764 0.999999999684511 GO:0015297 antiporter activity 5/1075 135/18639 0.037037037037037 0.642170542635659 0.895336282115021 0.999999999684511 GO:0042162 telomeric DNA binding 1/1075 38/18639 0.0263157894736842 0.456279069767442 0.895617610364863 0.999999999684511 GO:0016779 nucleotidyltransferase activity 5/1075 136/18639 0.0367647058823529 0.637448700410397 0.898853444242729 0.999999999684511 GO:0008235 metalloexopeptidase activity 2/1075 66/18639 0.0303030303030303 0.525412262156448 0.900489833002213 0.999999999684511 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/1075 39/18639 0.0256410256410256 0.444579606440072 0.901650139199752 0.999999999684511 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/1075 91/18639 0.032967032967033 0.571602351137235 0.902176851155134 0.999999999684511 GO:0015144 carbohydrate transmembrane transporter activity 1/1075 40/18639 0.025 0.43346511627907 0.907334338143853 0.999999999684511 GO:0030331 nuclear estrogen receptor binding 1/1075 40/18639 0.025 0.43346511627907 0.907334338143853 0.999999999684511 GO:0009055 electron transfer activity 4/1075 116/18639 0.0344827586206897 0.597882919005613 0.907948884815299 0.999999999684511 GO:0003777 microtubule motor activity 2/1075 68/18639 0.0294117647058824 0.509958960328317 0.909520695338101 0.999999999684511 GO:0033218 amide binding 10/1075 247/18639 0.0404858299595142 0.701967799642218 0.909829695328195 0.999999999684511 GO:0042393 histone binding 10/1075 247/18639 0.0404858299595142 0.701967799642218 0.909829695328195 0.999999999684511 GO:0008514 organic anion transmembrane transporter activity 11/1075 269/18639 0.0408921933085502 0.709013573095876 0.912606863547081 0.999999999684511 GO:0001530 lipopolysaccharide binding 1/1075 41/18639 0.024390243902439 0.422892796369824 0.91269030279224 0.999999999684511 GO:0008227 G protein-coupled amine receptor activity 1/1075 41/18639 0.024390243902439 0.422892796369824 0.91269030279224 0.999999999684511 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/1075 41/18639 0.024390243902439 0.422892796369824 0.91269030279224 0.999999999684511 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/1075 41/18639 0.024390243902439 0.422892796369824 0.91269030279224 0.999999999684511 GO:0016859 cis-trans isomerase activity 1/1075 42/18639 0.0238095238095238 0.412823920265781 0.917736970417702 0.999999999684511 GO:0035198 miRNA binding 1/1075 42/18639 0.0238095238095238 0.412823920265781 0.917736970417702 0.999999999684511 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/1075 70/18639 0.0285714285714286 0.495388704318937 0.917779311113681 0.999999999684511 GO:0008234 cysteine-type peptidase activity 7/1075 187/18639 0.0374331550802139 0.649038676781495 0.919470781833152 0.999999999684511 GO:0016407 acetyltransferase activity 3/1075 96/18639 0.03125 0.541831395348837 0.920598927466166 0.999999999684511 GO:0015399 primary active transmembrane transporter activity 6/1075 166/18639 0.036144578313253 0.626696553656486 0.922095386860967 0.999999999684511 GO:0003697 single-stranded DNA binding 4/1075 121/18639 0.0330578512396694 0.57317701326158 0.923865951574181 0.999999999684511 GO:0004540 RNA nuclease activity 4/1075 121/18639 0.0330578512396694 0.57317701326158 0.923865951574181 0.999999999684511 GO:0015108 chloride transmembrane transporter activity 4/1075 121/18639 0.0330578512396694 0.57317701326158 0.923865951574181 0.999999999684511 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 6/1075 167/18639 0.0359281437125748 0.622943879682496 0.924639961345517 0.999999999684511 GO:0016790 thiolester hydrolase activity 1/1075 44/18639 0.0227272727272727 0.394059196617336 0.926972768487469 0.999999999684511 GO:0042626 ATPase-coupled transmembrane transporter activity 3/1075 98/18639 0.0306122448979592 0.530773611770289 0.927036064366261 0.999999999684511 GO:0042605 peptide antigen binding 1/1075 45/18639 0.0222222222222222 0.385302325581395 0.931194563264343 0.999999999684511 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/1075 46/18639 0.0217391304347826 0.376926188068756 0.935172504777241 0.999999999684511 GO:0051536 iron-sulfur cluster binding 2/1075 76/18639 0.0263157894736842 0.456279069767442 0.938498577624306 0.999999999684511 GO:0061749 forked DNA-dependent helicase activity 1/1075 47/18639 0.0212765957446809 0.368906481939634 0.938920665771404 0.999999999684511 GO:0140359 ABC-type transporter activity 1/1075 47/18639 0.0212765957446809 0.368906481939634 0.938920665771404 0.999999999684511 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/1075 47/18639 0.0212765957446809 0.368906481939634 0.938920665771404 0.999999999684511 GO:0005216 monoatomic ion channel activity 19/1075 448/18639 0.0424107142857143 0.735342607973422 0.939332450648551 0.999999999684511 GO:0140098 catalytic activity, acting on RNA 16/1075 387/18639 0.041343669250646 0.716841535965387 0.939504276446343 0.999999999684511 GO:0051540 metal cluster binding 2/1075 77/18639 0.025974025974026 0.45035336756267 0.94142946966454 0.999999999684511 GO:0009378 four-way junction helicase activity 1/1075 48/18639 0.0208333333333333 0.361220930232558 0.942452307568722 0.999999999684511 GO:0036121 double-stranded DNA helicase activity 1/1075 48/18639 0.0208333333333333 0.361220930232558 0.942452307568722 0.999999999684511 GO:0043138 3'-5' DNA helicase activity 1/1075 48/18639 0.0208333333333333 0.361220930232558 0.942452307568722 0.999999999684511 GO:0060590 ATPase regulator activity 1/1075 49/18639 0.0204081632653061 0.353849074513526 0.945779926812637 0.999999999684511 GO:0016835 carbon-oxygen lyase activity 2/1075 79/18639 0.0253164556962025 0.438952016485134 0.946897571392697 0.999999999684511 GO:0016887 ATP hydrolysis activity 17/1075 417/18639 0.0407673860911271 0.706849590095366 0.95167058873591 0.999999999684511 GO:0003743 translation initiation factor activity 1/1075 51/18639 0.0196078431372549 0.339972640218878 0.951869522612143 0.999999999684511 GO:0016830 carbon-carbon lyase activity 1/1075 51/18639 0.0196078431372549 0.339972640218878 0.951869522612143 0.999999999684511 GO:0004843 cysteine-type deubiquitinase activity 3/1075 108/18639 0.0277777777777778 0.481627906976744 0.952595340411224 0.999999999684511 GO:0051087 protein-folding chaperone binding 4/1075 134/18639 0.0298507462686567 0.517570288094412 0.954302878991976 0.999999999684511 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/1075 52/18639 0.0192307692307692 0.333434704830054 0.954653053018424 0.999999999684511 GO:0005254 chloride channel activity 2/1075 83/18639 0.0240963855421687 0.417797702437658 0.956408474121808 0.999999999684511 GO:0004222 metalloendopeptidase activity 3/1075 110/18639 0.0272727272727273 0.472871035940803 0.956581414312399 0.999999999684511 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/1075 53/18639 0.0188679245283019 0.327143483984204 0.957275744577319 0.999999999684511 GO:0016860 intramolecular oxidoreductase activity 1/1075 53/18639 0.0188679245283019 0.327143483984204 0.957275744577319 0.999999999684511 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/1075 53/18639 0.0188679245283019 0.327143483984204 0.957275744577319 0.999999999684511 GO:0043022 ribosome binding 3/1075 112/18639 0.0267857142857143 0.464426910299003 0.960251875828231 0.999999999684511 GO:0004518 nuclease activity 7/1075 209/18639 0.0334928229665072 0.580718816067653 0.960640762055551 0.999999999684511 GO:0030170 pyridoxal phosphate binding 1/1075 56/18639 0.0178571428571429 0.309617940199336 0.964268993940191 0.999999999684511 GO:0015103 inorganic anion transmembrane transporter activity 5/1075 165/18639 0.0303030303030303 0.525412262156448 0.964702941398453 0.999999999684511 GO:0101005 deubiquitinase activity 3/1075 115/18639 0.0260869565217391 0.452311425682508 0.965215100229412 0.999999999684511 GO:0070279 vitamin B6 binding 1/1075 57/18639 0.0175438596491228 0.304186046511628 0.966335981590963 0.999999999684511 GO:0020037 heme binding 4/1075 142/18639 0.028169014084507 0.488411398624304 0.96698296839399 0.999999999684511 GO:0003727 single-stranded RNA binding 2/1075 89/18639 0.0224719101123595 0.389631565194669 0.967678872839686 0.999999999684511 GO:0017116 single-stranded DNA helicase activity 1/1075 58/18639 0.0172413793103448 0.298941459502807 0.968283501760466 0.999999999684511 GO:0061980 regulatory RNA binding 1/1075 58/18639 0.0172413793103448 0.298941459502807 0.968283501760466 0.999999999684511 GO:0001098 basal transcription machinery binding 1/1075 60/18639 0.0166666666666667 0.288976744186046 0.971847337244727 0.999999999684511 GO:0001099 basal RNA polymerase II transcription machinery binding 1/1075 60/18639 0.0166666666666667 0.288976744186046 0.971847337244727 0.999999999684511 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/1075 60/18639 0.0166666666666667 0.288976744186046 0.971847337244727 0.999999999684511 GO:0008509 monoatomic anion transmembrane transporter activity 4/1075 149/18639 0.0268456375838926 0.465465896675511 0.975306364232524 0.999999999684511 GO:0022824 transmitter-gated monoatomic ion channel activity 1/1075 63/18639 0.0158730158730159 0.275215946843854 0.976457093357834 0.999999999684511 GO:0022835 transmitter-gated channel activity 1/1075 63/18639 0.0158730158730159 0.275215946843854 0.976457093357834 0.999999999684511 GO:1901682 sulfur compound transmembrane transporter activity 1/1075 63/18639 0.0158730158730159 0.275215946843854 0.976457093357834 0.999999999684511 GO:0016829 lyase activity 6/1075 200/18639 0.03 0.520158139534884 0.976494295275609 0.999999999684511 GO:0030594 neurotransmitter receptor activity 2/1075 97/18639 0.0206185567010309 0.357497003116759 0.978421722210131 0.999999999684511 GO:0160215 deacylase activity 1/1075 65/18639 0.0153846153846154 0.266747763864043 0.979103191196996 0.999999999684511 GO:0061775 cohesin loader activity 4/1075 153/18639 0.0261437908496732 0.453296853625171 0.979132759231269 0.999999999684511 GO:0008168 methyltransferase activity 6/1075 204/18639 0.0294117647058824 0.509958960328317 0.97975652299016 0.999999999684511 GO:0019783 ubiquitin-like protein peptidase activity 3/1075 127/18639 0.0236220472440945 0.409573338216444 0.979798195552628 0.999999999684511 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/1075 67/18639 0.0149253731343284 0.258785144047206 0.981452127044154 0.999999999684511 GO:0030145 manganese ion binding 1/1075 68/18639 0.0147058823529412 0.254979480164159 0.982525730502453 0.999999999684511 GO:0140223 general transcription initiation factor activity 1/1075 68/18639 0.0147058823529412 0.254979480164159 0.982525730502453 0.999999999684511 GO:0008237 metallopeptidase activity 5/1075 184/18639 0.0271739130434783 0.471157735085945 0.983235314345038 0.999999999684511 GO:0008238 exopeptidase activity 2/1075 102/18639 0.0196078431372549 0.339972640218878 0.983282113278469 0.999999999684511 GO:0005253 monoatomic anion channel activity 2/1075 103/18639 0.0194174757281553 0.336671934974035 0.984117648721075 0.999999999684511 GO:0140299 molecular sensor activity 1/1075 71/18639 0.0140845070422535 0.244205699312152 0.985388151575402 0.999999999684511 GO:0016741 transferase activity, transferring one-carbon groups 6/1075 215/18639 0.027906976744186 0.483868036776636 0.986684218431609 0.999999999684511 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/1075 73/18639 0.0136986301369863 0.237515132207709 0.987031132344907 0.999999999684511 GO:0003678 DNA helicase activity 1/1075 74/18639 0.0135135135135135 0.234305468258957 0.987782049760033 0.999999999684511 GO:0035064 methylated histone binding 1/1075 74/18639 0.0135135135135135 0.234305468258957 0.987782049760033 0.999999999684511 GO:0044183 protein folding chaperone 1/1075 75/18639 0.0133333333333333 0.231181395348837 0.988489526006086 0.999999999684511 GO:0140034 methylation-dependent protein binding 1/1075 76/18639 0.0131578947368421 0.228139534883721 0.989156071984509 0.999999999684511 GO:0003724 RNA helicase activity 1/1075 77/18639 0.012987012987013 0.225176683781335 0.989784053593982 0.999999999684511 GO:0008186 ATP-dependent activity, acting on RNA 1/1075 79/18639 0.0126582278481013 0.219476008242567 0.990933112003327 0.999999999684511 GO:0043021 ribonucleoprotein complex binding 4/1075 177/18639 0.0225988700564972 0.391832873472605 0.992641644657913 0.999999999684511 GO:0008135 translation factor activity, RNA binding 1/1075 83/18639 0.0120481927710843 0.208898851218829 0.992858321802669 0.999999999684511 GO:0180051 translation factor activity 1/1075 84/18639 0.0119047619047619 0.20641196013289 0.993272058818305 0.999999999684511 GO:0000510 H3-H4 histone complex chaperone activity 3/1075 151/18639 0.0198675496688742 0.344475589095949 0.993454816238462 0.999999999684511 GO:0140584 chromatin extrusion motor activity 3/1075 151/18639 0.0198675496688742 0.344475589095949 0.993454816238462 0.999999999684511 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/1075 151/18639 0.0198675496688742 0.344475589095949 0.993454816238462 0.999999999684511 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/1075 151/18639 0.0198675496688742 0.344475589095949 0.993454816238462 0.999999999684511 GO:0051082 unfolded protein binding 2/1075 121/18639 0.0165289256198347 0.28658850663079 0.993761193936032 0.999999999684511 GO:0015616 DNA translocase activity 3/1075 152/18639 0.0197368421052632 0.342209302325581 0.993761310211409 0.999999999684511 GO:0140674 ATP-dependent histone chaperone activity 3/1075 152/18639 0.0197368421052632 0.342209302325581 0.993761310211409 0.999999999684511 GO:0140658 ATP-dependent chromatin remodeler activity 3/1075 158/18639 0.0189873417721519 0.32921401236385 0.995328289452946 0.999999999684511 GO:0140597 protein carrier chaperone 4/1075 188/18639 0.0212765957446809 0.368906481939634 0.995509784456473 0.999999999684511 GO:0003689 DNA clamp loader activity 3/1075 160/18639 0.01875 0.325098837209302 0.995760009256252 0.999999999684511 GO:0140713 histone chaperone activity 3/1075 164/18639 0.0182926829268293 0.317169597277368 0.996510204728611 0.999999999684511 GO:0140030 modification-dependent protein binding 3/1075 173/18639 0.0173410404624277 0.300669444817852 0.997756426706369 0.999999999684511 GO:0003823 antigen binding 3/1075 174/18639 0.0172413793103448 0.298941459502807 0.997864532457781 0.999999999684511 GO:0008094 ATP-dependent activity, acting on DNA 4/1075 210/18639 0.019047619047619 0.330259136212625 0.998370265439248 0.999999999684511 GO:0140104 molecular carrier activity 5/1075 249/18639 0.0200803212851406 0.348164752031381 0.998962683158451 0.999999999684511 GO:0004386 helicase activity 2/1075 155/18639 0.0129032258064516 0.223723930982746 0.998981148629181 0.999999999684511 GO:0008528 G protein-coupled peptide receptor activity 1/1075 122/18639 0.00819672131147541 0.142119710255433 0.999305092970508 0.999999999684511 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/1075 122/18639 0.00819672131147541 0.142119710255433 0.999305092970508 0.999999999684511 GO:0004519 endonuclease activity 1/1075 127/18639 0.0078740157480315 0.136524446072148 0.999484723275838 0.999999999684511 GO:0001653 peptide receptor activity 1/1075 128/18639 0.0078125 0.135457848837209 0.999514645622342 0.999999999684511 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/1075 132/18639 0.00757575757575758 0.131353065539112 0.999617951772484 0.999999999684511 GO:0016853 isomerase activity 2/1075 180/18639 0.0111111111111111 0.192651162790698 0.999738849321665 0.999999999684511 GO:0003730 mRNA 3'-UTR binding 4/1075 262/18639 0.0152671755725191 0.264711521391798 0.999866748260036 0.999999999684511 GO:0003735 structural constituent of ribosome 1/1075 175/18639 0.00571428571428571 0.0990777408637874 0.999970940333448 0.999999999684511 GO:0140097 catalytic activity, acting on DNA 5/1075 336/18639 0.0148809523809524 0.258014950166113 0.99998288901143 0.999999999684511 GO:0045182 translation regulator activity 2/1075 356/18639 0.00561797752808989 0.0974078912986674 0.99999998768642 0.999999999684511 GO:0004984 olfactory receptor activity 2/1075 419/18639 0.00477326968973747 0.0827618360437365 0.999999999684511 0.999999999684511