ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	50/422	175/18639	0.285714285714286	12.6194989844279	4.72461587403236e-41	3.26470956895636e-38
GO:0005201	extracellular matrix structural constituent	21/422	168/18639	0.125	5.5210308056872	2.33378518083879e-10	8.06322779979801e-08
GO:0031386	protein tag activity	6/422	15/18639	0.4	17.6672985781991	5.4723760153357e-07	9.45352956649241e-05
GO:0141047	molecular tag activity	6/422	15/18639	0.4	17.6672985781991	5.4723760153357e-07	9.45352956649241e-05
GO:0070492	oligosaccharide binding	6/422	17/18639	0.352941176470588	15.5887928631168	1.30205169271435e-06	0.000179943543933123
GO:0023026	MHC class II protein complex binding	7/422	27/18639	0.259259259259259	11.4510268562401	1.74148508624872e-06	0.000200561032432978
GO:0019838	growth factor binding	14/422	136/18639	0.102941176470588	4.5467312517424	2.59045774109727e-06	0.000255715185585459
GO:0008009	chemokine activity	8/422	45/18639	0.177777777777778	7.8521327014218	6.68368498124574e-06	0.000525844969271403
GO:0005125	cytokine activity	18/422	234/18639	0.0769230769230769	3.39755741888443	6.84892145216009e-06	0.000525844969271403
GO:0023023	MHC protein complex binding	7/422	37/18639	0.189189189189189	8.35615473293199	1.66057347894945e-05	0.00114745627395407
GO:0050840	extracellular matrix binding	9/422	67/18639	0.134328358208955	5.93304802999222	1.9204444441956e-05	0.00120638828267196
GO:0003746	translation elongation factor activity	5/422	18/18639	0.277777777777778	12.2689573459716	3.90191007755337e-05	0.00224684988632448
GO:0044389	ubiquitin-like protein ligase binding	20/422	322/18639	0.062111801242236	2.74336934444085	4.91145636973354e-05	0.0025652641115159
GO:0005520	insulin-like growth factor binding	5/422	19/18639	0.263157894736842	11.6232227488152	5.1973513113202e-05	0.0025652641115159
GO:0031625	ubiquitin protein ligase binding	19/422	302/18639	0.0629139072847682	2.77879696180283	6.36464715965025e-05	0.00293198079154555
GO:0050786	RAGE receptor binding	4/422	11/18639	0.363636363636364	16.0611805256355	7.53516954878921e-05	0.00306282479894902
GO:1990948	ubiquitin ligase inhibitor activity	4/422	11/18639	0.363636363636364	16.0611805256355	7.53516954878921e-05	0.00306282479894902
GO:0048306	calcium-dependent protein binding	9/422	80/18639	0.1125	4.96892772511848	8.03949312008262e-05	0.00308627208109838
GO:0019843	rRNA binding	8/422	65/18639	0.123076923076923	5.43609187021509	0.000105457416834852	0.00383531973857277
GO:0048027	mRNA 5'-UTR binding	5/422	24/18639	0.208333333333333	9.20171800947867	0.000173048803417498	0.00597883615807455
GO:0042379	chemokine receptor binding	8/422	72/18639	0.111111111111111	4.90758293838863	0.000217906914303633	0.00717017513256241
GO:0044183	protein folding chaperone	8/422	75/18639	0.106666666666667	4.71127962085308	0.000289575263065633	0.00871369453415322
GO:0055105	ubiquitin-protein transferase inhibitor activity	4/422	15/18639	0.266666666666667	11.7781990521327	0.000290036142236648	0.00871369453415322
GO:0005178	integrin binding	12/422	161/18639	0.0745341614906832	3.29204321332902	0.000310250640948382	0.00893263303730549
GO:0001664	G protein-coupled receptor binding	17/422	297/18639	0.0572390572390572	2.52814878644263	0.000462049678013429	0.0127710531002912
GO:0042605	peptide antigen binding	6/422	45/18639	0.133333333333333	5.88909952606635	0.000501411788826799	0.013279658288428
GO:0001968	fibronectin binding	5/422	30/18639	0.166666666666667	7.36137440758294	0.000518886792746102	0.013279658288428
GO:0004857	enzyme inhibitor activity	21/422	416/18639	0.0504807692307692	2.22964705614291	0.000560058116153758	0.0138214342236517
GO:0019207	kinase regulator activity	16/422	287/18639	0.0557491289198606	2.46234126525422	0.000891293744874334	0.0212373785416608
GO:0002020	protease binding	10/422	136/18639	0.0735294117647059	3.247665179816	0.00107300354774346	0.0247148483830243
GO:0008083	growth factor activity	11/422	162/18639	0.0679012345679012	2.9990784623486	0.00118280258161547	0.0257158089130099
GO:0005518	collagen binding	7/422	72/18639	0.0972222222222222	4.29413507109005	0.00120476007474772	0.0257158089130099
GO:0055106	ubiquitin-protein transferase regulator activity	5/422	36/18639	0.138888888888889	6.13447867298578	0.00122810664852291	0.0257158089130099
GO:0005126	cytokine receptor binding	15/422	275/18639	0.0545454545454545	2.40917707884533	0.0015840446089758	0.0316096951556057
GO:0019955	cytokine binding	10/422	144/18639	0.0694444444444444	3.06723933649289	0.00165244425830653	0.0316096951556057
GO:0050998	nitric-oxide synthase binding	3/422	11/18639	0.272727272727273	12.0458853942266	0.00166063943436732	0.0316096951556057
GO:0042277	peptide binding	14/422	249/18639	0.0562248995983936	2.48335522183521	0.00169255965377339	0.0316096951556057
GO:0019209	kinase activator activity	10/422	148/18639	0.0675675675675676	2.98434097604714	0.0020251730535957	0.036826173158806
GO:0019887	protein kinase regulator activity	14/422	255/18639	0.0549019607843137	2.42492333426261	0.00211048392227171	0.0373934459048655
GO:0008135	translation factor activity, RNA binding	7/422	83/18639	0.0843373493975904	3.72503283275281	0.00274762885675796	0.0457884824133477
GO:0031994	insulin-like growth factor I binding	3/422	13/18639	0.230769230769231	10.1926722566533	0.0027830915504495	0.0457884824133477
GO:0039706	co-receptor binding	3/422	13/18639	0.230769230769231	10.1926722566533	0.0027830915504495	0.0457884824133477
GO:0180051	translation factor activity	7/422	84/18639	0.0833333333333333	3.68068720379147	0.0029403952094234	0.0459055044001397
GO:0005507	copper ion binding	6/422	63/18639	0.0952380952380952	4.20649966147596	0.00297372951017437	0.0459055044001397
GO:0031072	heat shock protein binding	9/422	131/18639	0.0687022900763359	3.03445967946167	0.00298950462808435	0.0459055044001397
GO:0008191	metalloendopeptidase inhibitor activity	3/422	14/18639	0.214285714285714	9.46462423832092	0.00348305723508633	0.0523215771618404
GO:0043236	laminin binding	4/422	29/18639	0.137931034482759	6.09217192351691	0.00392963118355078	0.0569322056009742
GO:0043177	organic acid binding	11/422	189/18639	0.0582010582010582	2.57063868201309	0.00395476970889546	0.0569322056009742
GO:0030295	protein kinase activator activity	9/422	139/18639	0.0647482014388489	2.8598145180538	0.0044286133959516	0.0624524868694399
GO:0030246	carbohydrate binding	14/422	280/18639	0.05	2.20841232227488	0.00487285888465	0.0673429097858629
GO:0051213	dioxygenase activity	7/422	93/18639	0.0752688172043011	3.32449166794068	0.00517559934841358	0.068856214247675
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/422	16/18639	0.1875	8.28154620853081	0.00518165432833445	0.068856214247675
GO:0048020	CCR chemokine receptor binding	5/422	50/18639	0.1	4.41682464454976	0.00533167552299912	0.0695129771017433
GO:0051082	unfolded protein binding	8/422	121/18639	0.0661157024793388	2.92021464102464	0.006296783434743	0.0778173585274635
GO:0019956	chemokine binding	4/422	33/18639	0.121212121212121	5.3537268418785	0.00630647189224017	0.0778173585274635
GO:0140311	protein sequestering activity	4/422	33/18639	0.121212121212121	5.3537268418785	0.00630647189224017	0.0778173585274635
GO:0016860	intramolecular oxidoreductase activity	5/422	53/18639	0.0943396226415094	4.16681570240544	0.00683461918273105	0.0828547693906519
GO:0098641	cadherin binding involved in cell-cell adhesion	3/422	18/18639	0.166666666666667	7.36137440758294	0.00730173681855712	0.0869913817521202
GO:0140313	molecular sequestering activity	5/422	55/18639	0.0909090909090909	4.01529513140888	0.0079872105686053	0.0935451271679028
GO:0045296	cadherin binding	15/422	334/18639	0.0449101796407186	1.98360388228283	0.00947966034907564	0.109174088353521
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/422	20/18639	0.15	6.62523696682464	0.00986577411996592	0.110993255019151
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	5/422	58/18639	0.0862068965517241	3.80760745219807	0.00995887382226824	0.110993255019151
GO:0031406	carboxylic acid binding	10/422	187/18639	0.053475935828877	2.36193831259346	0.0103820897376488	0.113873396963735
GO:0004860	protein kinase inhibitor activity	6/422	84/18639	0.0714285714285714	3.15487474610697	0.0119927145368851	0.129483839765431
GO:0140662	ATP-dependent protein folding chaperone	4/422	40/18639	0.1	4.41682464454976	0.0124469737717834	0.132320905789266
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/422	22/18639	0.136363636363636	6.02294269711331	0.0128905753675183	0.132946083267987
GO:0033691	sialic acid binding	3/422	22/18639	0.136363636363636	6.02294269711331	0.0128905753675183	0.132946083267987
GO:0008137	NADH dehydrogenase (ubiquinone) activity	4/422	41/18639	0.0975609756097561	4.30909721419489	0.0135519772125379	0.13771200373329
GO:0035198	miRNA binding	4/422	42/18639	0.0952380952380952	4.20649966147596	0.0147174215227207	0.145281975317143
GO:0042056	chemoattractant activity	4/422	42/18639	0.0952380952380952	4.20649966147596	0.0147174215227207	0.145281975317143
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/422	24/18639	0.125	5.5210308056872	0.0163878730301121	0.152671653003069
GO:0050431	transforming growth factor beta binding	3/422	24/18639	0.125	5.5210308056872	0.0163878730301121	0.152671653003069
GO:0019210	kinase inhibitor activity	6/422	90/18639	0.0666666666666667	2.94454976303318	0.0164247029152193	0.152671653003069
GO:0009055	electron transfer activity	7/422	116/18639	0.0603448275862069	2.66532521653865	0.0164380920857859	0.152671653003069
GO:0008201	heparin binding	9/422	172/18639	0.0523255813953488	2.31112917447371	0.0166588685340702	0.152671653003069
GO:0003954	NADH dehydrogenase activity	4/422	44/18639	0.0909090909090909	4.01529513140888	0.0172335585155418	0.152671653003069
GO:0030020	extracellular matrix structural constituent conferring tensile strength	4/422	44/18639	0.0909090909090909	4.01529513140888	0.0172335585155418	0.152671653003069
GO:0030547	signaling receptor inhibitor activity	4/422	44/18639	0.0909090909090909	4.01529513140888	0.0172335585155418	0.152671653003069
GO:0022853	active monoatomic ion transmembrane transporter activity	7/422	118/18639	0.0593220338983051	2.6201502128685	0.0178957240796751	0.156252327472073
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/422	25/18639	0.12	5.30018957345971	0.018316119428709	0.156252327472073
GO:0019211	phosphatase activator activity	3/422	25/18639	0.12	5.30018957345971	0.018316119428709	0.156252327472073
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	5/422	68/18639	0.0735294117647059	3.247665179816	0.018884181259555	0.157216496992199
GO:1990841	promoter-specific chromatin binding	5/422	68/18639	0.0735294117647059	3.247665179816	0.018884181259555	0.157216496992199
GO:0005131	growth hormone receptor binding	2/422	10/18639	0.2	8.83364928909953	0.0204051228351826	0.165881645636602
GO:0032395	MHC class II receptor activity	2/422	10/18639	0.2	8.83364928909953	0.0204051228351826	0.165881645636602
GO:0005504	fatty acid binding	4/422	47/18639	0.0851063829787234	3.75899969748916	0.0214838398596721	0.172620155151551
GO:0005539	glycosaminoglycan binding	11/422	242/18639	0.0454545454545455	2.00764756570444	0.0224332259638468	0.178176541850784
GO:0048407	platelet-derived growth factor binding	2/422	11/18639	0.181818181818182	8.03059026281775	0.0245705635909193	0.192934766378696
GO:0098631	cell adhesion mediator activity	5/422	76/18639	0.0657894736842105	2.90580568720379	0.0289569563333088	0.211294996621204
GO:0004126	cytidine deaminase activity	2/422	12/18639	0.166666666666667	7.36137440758294	0.0290492397670252	0.211294996621204
GO:0004859	phospholipase inhibitor activity	2/422	12/18639	0.166666666666667	7.36137440758294	0.0290492397670252	0.211294996621204
GO:0015269	calcium-activated potassium channel activity	2/422	12/18639	0.166666666666667	7.36137440758294	0.0290492397670252	0.211294996621204
GO:0031543	peptidyl-proline dioxygenase activity	2/422	12/18639	0.166666666666667	7.36137440758294	0.0290492397670252	0.211294996621204
GO:0035497	cAMP response element binding	2/422	12/18639	0.166666666666667	7.36137440758294	0.0290492397670252	0.211294996621204
GO:0097371	MDM2/MDM4 family protein binding	2/422	12/18639	0.166666666666667	7.36137440758294	0.0290492397670252	0.211294996621204
GO:0048019	receptor antagonist activity	3/422	30/18639	0.1	4.41682464454976	0.0297669087564861	0.214259728653457
GO:0051087	protein-folding chaperone binding	7/422	134/18639	0.0522388059701493	2.30729645610809	0.0329433961140907	0.233730080276787
GO:0046332	SMAD binding	5/422	79/18639	0.0632911392405063	2.79545863579099	0.0334646304549834	0.233730080276787
GO:0035325	Toll-like receptor binding	2/422	13/18639	0.153846153846154	6.79511483776887	0.0338249030791298	0.233730080276787
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/422	13/18639	0.153846153846154	6.79511483776887	0.0338249030791298	0.233730080276787
GO:0043425	bHLH transcription factor binding	3/422	32/18639	0.09375	4.1407731042654	0.035187914221458	0.240741076505223
GO:0001618	virus receptor activity	5/422	81/18639	0.0617283950617284	2.72643496577146	0.0366988518550087	0.248616731684422
GO:0019239	deaminase activity	3/422	33/18639	0.0909090909090909	4.01529513140888	0.0380760584543798	0.248772011796769
GO:0030296	protein tyrosine kinase activator activity	3/422	33/18639	0.0909090909090909	4.01529513140888	0.0380760584543798	0.248772011796769
GO:0140272	exogenous protein binding	5/422	82/18639	0.0609756097560976	2.69318575887181	0.0383854953128291	0.248772011796769
GO:0005161	platelet-derived growth factor receptor binding	2/422	14/18639	0.142857142857143	6.30974949221395	0.0388818773864704	0.248772011796769
GO:0032036	myosin heavy chain binding	2/422	14/18639	0.142857142857143	6.30974949221395	0.0388818773864704	0.248772011796769
GO:0042043	neurexin family protein binding	2/422	14/18639	0.142857142857143	6.30974949221395	0.0388818773864704	0.248772011796769
GO:0001540	amyloid-beta binding	5/422	83/18639	0.0602409638554217	2.66073773768058	0.040118788582933	0.25433103587896
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	3/422	34/18639	0.0882352941176471	3.8971982157792	0.0410812985476153	0.258065248149111
GO:0061980	regulatory RNA binding	4/422	58/18639	0.0689655172413793	3.04608596175846	0.0421952154896432	0.262511443072315
GO:0005154	epidermal growth factor receptor binding	3/422	35/18639	0.0857142857142857	3.78584969532837	0.0442024556213349	0.262511443072315
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/422	15/18639	0.133333333333333	5.88909952606635	0.0442050412138815	0.262511443072315
GO:0051371	muscle alpha-actinin binding	2/422	15/18639	0.133333333333333	5.88909952606635	0.0442050412138815	0.262511443072315
GO:0140776	protein-containing complex destabilizing activity	2/422	15/18639	0.133333333333333	5.88909952606635	0.0442050412138815	0.262511443072315
GO:0004879	nuclear receptor activity	4/422	59/18639	0.0677966101694915	2.99445738613543	0.0444869354722433	0.262511443072315
GO:0015459	potassium channel regulator activity	4/422	59/18639	0.0677966101694915	2.99445738613543	0.0444869354722433	0.262511443072315
GO:0003823	antigen binding	8/422	174/18639	0.0459770114942529	2.03072397450564	0.0448282927388323	0.262511443072315
GO:0005516	calmodulin binding	9/422	207/18639	0.0434782608695652	1.92035854110859	0.0465660448051221	0.266502512727795
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	4/422	60/18639	0.0666666666666667	2.94454976303318	0.0468471066250911	0.266502512727795
GO:0098531	ligand-modulated transcription factor activity	4/422	60/18639	0.0666666666666667	2.94454976303318	0.0468471066250911	0.266502512727795
GO:0004252	serine-type endopeptidase activity	8/422	176/18639	0.0454545454545455	2.00764756570444	0.04738048693272	0.266502512727795
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/422	36/18639	0.0833333333333333	3.68068720379147	0.0474382186186957	0.266502512727795
GO:0043021	ribonucleoprotein complex binding	8/422	177/18639	0.0451977401129944	1.99630492409029	0.0486914268184469	0.268733197198056
GO:0016651	oxidoreductase activity, acting on NAD(P)H	5/422	88/18639	0.0568181818181818	2.50955945713055	0.0494906775827208	0.268733197198056
GO:0008142	oxysterol binding	2/422	16/18639	0.125	5.5210308056872	0.0497798107689596	0.268733197198056
GO:0019841	retinol binding	2/422	16/18639	0.125	5.5210308056872	0.0497798107689596	0.268733197198056
GO:0055102	lipase inhibitor activity	2/422	16/18639	0.125	5.5210308056872	0.0497798107689596	0.268733197198056
GO:0043394	proteoglycan binding	3/422	37/18639	0.0810810810810811	3.58120917125656	0.05078715366773	0.272045916158151
GO:0005501	retinoid binding	3/422	38/18639	0.0789473684210526	3.48696682464455	0.054247713026745	0.278363458679323
GO:0019840	isoprenoid binding	3/422	38/18639	0.0789473684210526	3.48696682464455	0.054247713026745	0.278363458679323
GO:0033218	amide binding	10/422	247/18639	0.0404858299595142	1.78818811520233	0.0553375013946986	0.278363458679323
GO:0004550	nucleoside diphosphate kinase activity	2/422	17/18639	0.117647058823529	5.1962642877056	0.0555921234410225	0.278363458679323
GO:0008429	phosphatidylethanolamine binding	2/422	17/18639	0.117647058823529	5.1962642877056	0.0555921234410225	0.278363458679323
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/422	17/18639	0.117647058823529	5.1962642877056	0.0555921234410225	0.278363458679323
GO:0036041	long-chain fatty acid binding	2/422	17/18639	0.117647058823529	5.1962642877056	0.0555921234410225	0.278363458679323
GO:0045236	CXCR chemokine receptor binding	2/422	17/18639	0.117647058823529	5.1962642877056	0.0555921234410225	0.278363458679323
GO:0051787	misfolded protein binding	2/422	17/18639	0.117647058823529	5.1962642877056	0.0555921234410225	0.278363458679323
GO:0061135	endopeptidase regulator activity	8/422	184/18639	0.0434782608695652	1.92035854110859	0.0585276884490436	0.290954192217907
GO:0005506	iron ion binding	7/422	154/18639	0.0454545454545455	2.00764756570444	0.0612805581963076	0.297798877218615
GO:0016854	racemase and epimerase activity	2/422	18/18639	0.111111111111111	4.90758293838863	0.0616284217688306	0.297798877218615
GO:0031690	adrenergic receptor binding	2/422	18/18639	0.111111111111111	4.90758293838863	0.0616284217688306	0.297798877218615
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	2/422	18/18639	0.111111111111111	4.90758293838863	0.0616284217688306	0.297798877218615
GO:0140375	immune receptor activity	7/422	156/18639	0.0448717948717949	1.98190849434925	0.0647401495767253	0.310662801093869
GO:0016918	retinal binding	2/422	19/18639	0.105263157894737	4.64928909952607	0.0678756378643833	0.323462522512337
GO:0042826	histone deacetylase binding	6/422	127/18639	0.047244094488189	2.08668880844871	0.068960409079973	0.326381114207269
GO:0061134	peptidase regulator activity	9/422	226/18639	0.0398230088495575	1.75891246906849	0.0724599297212673	0.337001685865303
GO:0048156	tau protein binding	3/422	43/18639	0.0697674418604651	3.08150556596495	0.0731637772720834	0.337001685865303
GO:0004866	endopeptidase inhibitor activity	7/422	161/18639	0.0434782608695652	1.92035854110859	0.0738975723586485	0.337001685865303
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/422	20/18639	0.1	4.41682464454976	0.0743211782804297	0.337001685865303
GO:0016004	phospholipase activator activity	2/422	20/18639	0.1	4.41682464454976	0.0743211782804297	0.337001685865303
GO:0031418	L-ascorbic acid binding	2/422	20/18639	0.1	4.41682464454976	0.0743211782804297	0.337001685865303
GO:0008236	serine-type peptidase activity	8/422	194/18639	0.0412371134020619	1.8213709874432	0.0746183182885548	0.337001685865303
GO:0004175	endopeptidase activity	14/422	405/18639	0.0345679012345679	1.52680358083202	0.0780752100110194	0.35032448128321
GO:0003779	actin binding	15/422	443/18639	0.0338600451467269	1.49553881869631	0.0801309519041301	0.357228953327444
GO:0072542	protein phosphatase activator activity	2/422	21/18639	0.0952380952380952	4.20649966147596	0.0809529093096628	0.35857987392934
GO:0017171	serine hydrolase activity	8/422	198/18639	0.0404040404040404	1.7845756139595	0.081733851710423	0.35973306708218
GO:0015399	primary active transmembrane transporter activity	7/422	166/18639	0.0421686746987952	1.86251641637641	0.0837811901551423	0.366410141754452
GO:0044325	transmembrane transporter binding	6/422	136/18639	0.0441176470588235	1.9485991078896	0.0890162706181903	0.386856874196035
GO:0030414	peptidase inhibitor activity	7/422	169/18639	0.0414201183431953	1.82945399478393	0.0900581998942558	0.388938850793317
GO:0016922	nuclear receptor binding	6/422	137/18639	0.0437956204379562	1.93437575673712	0.0914221617901342	0.389627843243812
GO:0140693	molecular condensate scaffold activity	3/422	48/18639	0.0625	2.7605154028436	0.0945867170537847	0.389627843243812
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/422	23/18639	0.0869565217391304	3.84071708221718	0.0947286218016794	0.389627843243812
GO:0005212	structural constituent of eye lens	2/422	23/18639	0.0869565217391304	3.84071708221718	0.0947286218016794	0.389627843243812
GO:0016849	phosphorus-oxygen lyase activity	2/422	23/18639	0.0869565217391304	3.84071708221718	0.0947286218016794	0.389627843243812
GO:0017134	fibroblast growth factor binding	2/422	23/18639	0.0869565217391304	3.84071708221718	0.0947286218016794	0.389627843243812
GO:0031681	G-protein beta-subunit binding	2/422	23/18639	0.0869565217391304	3.84071708221718	0.0947286218016794	0.389627843243812
GO:0099186	structural constituent of postsynapse	2/422	23/18639	0.0869565217391304	3.84071708221718	0.0947286218016794	0.389627843243812
GO:0070851	growth factor receptor binding	6/422	139/18639	0.0431654676258993	1.90654301203587	0.0963387374471871	0.391664410104152
GO:1901681	sulfur compound binding	10/422	275/18639	0.0363636363636364	1.60611805256355	0.0963573801992848	0.391664410104152
GO:0019957	C-C chemokine binding	2/422	24/18639	0.0833333333333333	3.68068720379147	0.10185050805364	0.406813300954135
GO:0060229	lipase activator activity	2/422	24/18639	0.0833333333333333	3.68068720379147	0.10185050805364	0.406813300954135
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/422	24/18639	0.0833333333333333	3.68068720379147	0.10185050805364	0.406813300954135
GO:0020037	heme binding	6/422	142/18639	0.0422535211267606	1.8662639343168	0.10397280310991	0.411606484822237
GO:0033293	monocarboxylic acid binding	4/422	79/18639	0.0506329113924051	2.23636690863279	0.104241873869597	0.411606484822237
GO:0003707	nuclear steroid receptor activity	2/422	25/18639	0.08	3.53345971563981	0.109114367934069	0.425977560691761
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/422	25/18639	0.08	3.53345971563981	0.109114367934069	0.425977560691761
GO:0043022	ribosome binding	5/422	112/18639	0.0446428571428571	1.97179671631686	0.11073969921561	0.429894000887566
GO:0030971	receptor tyrosine kinase binding	4/422	81/18639	0.0493827160493827	2.18114797261717	0.111580979343601	0.430739981711888
GO:0005080	protein kinase C binding	3/422	52/18639	0.0576923076923077	2.54816806416332	0.113344823843367	0.432714216993187
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	3/422	52/18639	0.0576923076923077	2.54816806416332	0.113344823843367	0.432714216993187
GO:0016853	isomerase activity	7/422	180/18639	0.0388888888888889	1.71765402843602	0.115259145349385	0.432841509237385
GO:0005227	calcium-activated cation channel activity	2/422	26/18639	0.0769230769230769	3.39755741888443	0.116510160228876	0.432841509237385
GO:0008198	ferrous iron binding	2/422	26/18639	0.0769230769230769	3.39755741888443	0.116510160228876	0.432841509237385
GO:0019865	immunoglobulin binding	2/422	26/18639	0.0769230769230769	3.39755741888443	0.116510160228876	0.432841509237385
GO:0050681	nuclear androgen receptor binding	2/422	26/18639	0.0769230769230769	3.39755741888443	0.116510160228876	0.432841509237385
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	7/422	181/18639	0.0386740331491713	1.70816422717394	0.117716759043119	0.434985457212809
GO:0001221	transcription coregulator binding	5/422	115/18639	0.0434782608695652	1.92035854110859	0.120195872389574	0.44178376500636
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	3/422	54/18639	0.0555555555555556	2.45379146919431	0.123211804753912	0.448101879394489
GO:0140463	chromatin-protein adaptor activity	3/422	54/18639	0.0555555555555556	2.45379146919431	0.123211804753912	0.448101879394489
GO:0015252	proton channel activity	2/422	27/18639	0.0740740740740741	3.27172195892575	0.124028223689264	0.448709437535507
GO:0019208	phosphatase regulator activity	5/422	117/18639	0.0427350427350427	1.88753189938024	0.126703772638057	0.453638895818122
GO:1990782	protein tyrosine kinase binding	5/422	117/18639	0.0427350427350427	1.88753189938024	0.126703772638057	0.453638895818122
GO:0015078	proton transmembrane transporter activity	7/422	185/18639	0.0378378378378378	1.6712309465864	0.127816516022932	0.45449643334951
GO:0098632	cell-cell adhesion mediator activity	3/422	55/18639	0.0545454545454545	2.40917707884533	0.128258761943784	0.45449643334951
GO:0016209	antioxidant activity	4/422	86/18639	0.0465116279069767	2.05433704397663	0.130887035966025	0.454882760717557
GO:0046906	tetrapyrrole binding	6/422	152/18639	0.0394736842105263	1.74348341232227	0.131591431329199	0.454882760717557
GO:0046625	sphingolipid binding	2/422	28/18639	0.0714285714285714	3.15487474610697	0.131659265041261	0.454882760717557
GO:0051393	alpha-actinin binding	2/422	28/18639	0.0714285714285714	3.15487474610697	0.131659265041261	0.454882760717557
GO:0097718	disordered domain specific binding	2/422	28/18639	0.0714285714285714	3.15487474610697	0.131659265041261	0.454882760717557
GO:0170055	lipid transmembrane transporter activity	3/422	56/18639	0.0535714285714286	2.36615605958023	0.133378086291032	0.458528644910962
GO:0004197	cysteine-type endopeptidase activity	4/422	88/18639	0.0454545454545455	2.00764756570444	0.138971967486872	0.469860946404317
GO:0003785	actin monomer binding	2/422	29/18639	0.0689655172413793	3.04608596175846	0.139394347341368	0.469860946404317
GO:0004181	metallocarboxypeptidase activity	2/422	29/18639	0.0689655172413793	3.04608596175846	0.139394347341368	0.469860946404317
GO:0051861	glycolipid binding	2/422	29/18639	0.0689655172413793	3.04608596175846	0.139394347341368	0.469860946404317
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/422	30/18639	0.0666666666666667	2.94454976303318	0.147224878668859	0.486757852441061
GO:0022839	monoatomic ion-gated channel activity	2/422	30/18639	0.0666666666666667	2.94454976303318	0.147224878668859	0.486757852441061
GO:0033612	receptor serine/threonine kinase binding	2/422	30/18639	0.0666666666666667	2.94454976303318	0.147224878668859	0.486757852441061
GO:0098918	structural constituent of synapse	2/422	30/18639	0.0666666666666667	2.94454976303318	0.147224878668859	0.486757852441061
GO:0001786	phosphatidylserine binding	3/422	59/18639	0.0508474576271186	2.24584303960157	0.149145599004252	0.488434165459421
GO:0070888	E-box binding	3/422	59/18639	0.0508474576271186	2.24584303960157	0.149145599004252	0.488434165459421
GO:0043178	alcohol binding	4/422	92/18639	0.0434782608695652	1.92035854110859	0.155717203524527	0.507549941676642
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/422	32/18639	0.0625	2.7605154028436	0.163139580273781	0.529246243986774
GO:0042562	hormone binding	4/422	94/18639	0.0425531914893617	1.87949984874458	0.164360041928978	0.530713967163197
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	11/422	349/18639	0.0315186246418338	1.39212238080365	0.170179552568645	0.5469491666276
GO:0004896	cytokine receptor activity	4/422	96/18639	0.0416666666666667	1.84034360189573	0.173171107232868	0.55398719952737
GO:0015035	protein-disulfide reductase activity	2/422	34/18639	0.0588235294117647	2.5981321438528	0.179341125587029	0.565866291235785
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/422	34/18639	0.0588235294117647	2.5981321438528	0.179341125587029	0.565866291235785
GO:0051427	hormone receptor binding	2/422	34/18639	0.0588235294117647	2.5981321438528	0.179341125587029	0.565866291235785
GO:0005179	hormone activity	5/422	132/18639	0.0378787878787879	1.67303963808703	0.180244332930334	0.566131063885731
GO:0016247	channel regulator activity	6/422	168/18639	0.0357142857142857	1.57743737305349	0.182117149341585	0.569425114004686
GO:0016229	steroid dehydrogenase activity	2/422	35/18639	0.0571428571428571	2.52389979688558	0.187531348009192	0.58257905851768
GO:0008235	metalloexopeptidase activity	3/422	66/18639	0.0454545454545455	2.00764756570444	0.188010318450713	0.58257905851768
GO:0141108	transporter regulator activity	6/422	170/18639	0.0352941176470588	1.55887928631168	0.188919158473152	0.582781868325661
GO:0043130	ubiquitin binding	4/422	100/18639	0.04	1.76672985781991	0.191261444678302	0.586987017805776
GO:0004033	aldo-keto reductase (NADPH) activity	2/422	36/18639	0.0555555555555556	2.45379146919431	0.19577212032628	0.586987017805776
GO:0032934	sterol binding	3/422	68/18639	0.0441176470588235	1.9485991078896	0.199560658868618	0.586987017805776
GO:0008238	exopeptidase activity	4/422	102/18639	0.0392156862745098	1.73208809590187	0.200522291164395	0.586987017805776
GO:0042805	actinin binding	2/422	37/18639	0.0540540540540541	2.38747278083771	0.204056975563911	0.586987017805776
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/422	10/18639	0.1	4.41682464454976	0.204723402736891	0.586987017805776
GO:0003796	lysozyme activity	1/422	10/18639	0.1	4.41682464454976	0.204723402736891	0.586987017805776
GO:0004090	carbonyl reductase (NADPH) activity	1/422	10/18639	0.1	4.41682464454976	0.204723402736891	0.586987017805776
GO:0005345	purine nucleobase transmembrane transporter activity	1/422	10/18639	0.1	4.41682464454976	0.204723402736891	0.586987017805776
GO:0005522	profilin binding	1/422	10/18639	0.1	4.41682464454976	0.204723402736891	0.586987017805776
GO:0008239	dipeptidyl-peptidase activity	1/422	10/18639	0.1	4.41682464454976	0.204723402736891	0.586987017805776
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/422	10/18639	0.1	4.41682464454976	0.204723402736891	0.586987017805776
GO:0030957	Tat protein binding	1/422	10/18639	0.1	4.41682464454976	0.204723402736891	0.586987017805776
GO:0031434	mitogen-activated protein kinase kinase binding	1/422	10/18639	0.1	4.41682464454976	0.204723402736891	0.586987017805776
GO:0043208	glycosphingolipid binding	1/422	10/18639	0.1	4.41682464454976	0.204723402736891	0.586987017805776
GO:0051880	G-quadruplex DNA binding	1/422	10/18639	0.1	4.41682464454976	0.204723402736891	0.586987017805776
GO:0141109	transporter activator activity	1/422	10/18639	0.1	4.41682464454976	0.204723402736891	0.586987017805776
GO:0140297	DNA-binding transcription factor binding	14/422	488/18639	0.0286885245901639	1.26712182425608	0.218657468325085	0.591970894139149
GO:0016776	phosphotransferase activity, phosphate group as acceptor	2/422	39/18639	0.0512820512820513	2.26503827925629	0.220734386357637	0.591970894139149
GO:0003953	NAD+ nucleosidase activity	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0005114	type II transforming growth factor beta receptor binding	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0008172	S-methyltransferase activity	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0008199	ferric iron binding	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0008503	benzodiazepine receptor activity	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0015205	nucleobase transmembrane transporter activity	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0019864	IgG binding	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0043522	leucine zipper domain binding	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0045294	alpha-catenin binding	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0070697	activin receptor binding	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0140031	phosphorylation-dependent protein binding	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0140537	transcription regulator activator activity	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:1900750	oligopeptide binding	1/422	11/18639	0.0909090909090909	4.01529513140888	0.222738686651489	0.591970894139149
GO:0019888	protein phosphatase regulator activity	4/422	107/18639	0.0373831775700935	1.65114939983169	0.224229144149881	0.593648806925546
GO:0043539	protein serine/threonine kinase activator activity	3/422	73/18639	0.0410958904109589	1.8151334155684	0.229112646370221	0.597408817866295
GO:0015036	disulfide oxidoreductase activity	2/422	40/18639	0.05	2.20841232227488	0.229115301679692	0.597408817866295
GO:0032451	demethylase activity	2/422	40/18639	0.05	2.20841232227488	0.229115301679692	0.597408817866295
GO:0071855	neuropeptide receptor binding	2/422	40/18639	0.05	2.20841232227488	0.229115301679692	0.597408817866295
GO:0003712	transcription coregulator activity	14/422	495/18639	0.0282828282828283	1.24920292977165	0.233880436940847	0.597408817866295
GO:0048029	monosaccharide binding	3/422	74/18639	0.0405405405405405	1.79060458562828	0.23512093811298	0.597408817866295
GO:0042169	SH2 domain binding	2/422	41/18639	0.0487804878048781	2.15454860709745	0.237517002881694	0.597408817866295
GO:0008237	metallopeptidase activity	6/422	184/18639	0.0326086956521739	1.44026890583144	0.239041107429087	0.597408817866295
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/422	12/18639	0.0833333333333333	3.68068720379147	0.24034681818644	0.597408817866295
GO:0015132	prostaglandin transmembrane transporter activity	1/422	12/18639	0.0833333333333333	3.68068720379147	0.24034681818644	0.597408817866295
GO:0017166	vinculin binding	1/422	12/18639	0.0833333333333333	3.68068720379147	0.24034681818644	0.597408817866295
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/422	12/18639	0.0833333333333333	3.68068720379147	0.24034681818644	0.597408817866295
GO:0035251	UDP-glucosyltransferase activity	1/422	12/18639	0.0833333333333333	3.68068720379147	0.24034681818644	0.597408817866295
GO:0045295	gamma-catenin binding	1/422	12/18639	0.0833333333333333	3.68068720379147	0.24034681818644	0.597408817866295
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/422	12/18639	0.0833333333333333	3.68068720379147	0.24034681818644	0.597408817866295
GO:0070410	co-SMAD binding	1/422	12/18639	0.0833333333333333	3.68068720379147	0.24034681818644	0.597408817866295
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/422	12/18639	0.0833333333333333	3.68068720379147	0.24034681818644	0.597408817866295
GO:0008307	structural constituent of muscle	2/422	42/18639	0.0476190476190476	2.10324983073798	0.245934266972523	0.602626164815651
GO:0019894	kinesin binding	2/422	42/18639	0.0476190476190476	2.10324983073798	0.245934266972523	0.602626164815651
GO:0031492	nucleosomal DNA binding	2/422	42/18639	0.0476190476190476	2.10324983073798	0.245934266972523	0.602626164815651
GO:0051879	Hsp90 protein binding	2/422	42/18639	0.0476190476190476	2.10324983073798	0.245934266972523	0.602626164815651
GO:0008200	ion channel inhibitor activity	2/422	43/18639	0.0465116279069767	2.05433704397663	0.254362095738398	0.611587187783823
GO:0008375	acetylglucosaminyltransferase activity	2/422	43/18639	0.0465116279069767	2.05433704397663	0.254362095738398	0.611587187783823
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/422	13/18639	0.0769230769230769	3.39755741888443	0.257556977778716	0.611587187783823
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/422	13/18639	0.0769230769230769	3.39755741888443	0.257556977778716	0.611587187783823
GO:0008253	5'-nucleotidase activity	1/422	13/18639	0.0769230769230769	3.39755741888443	0.257556977778716	0.611587187783823
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/422	13/18639	0.0769230769230769	3.39755741888443	0.257556977778716	0.611587187783823
GO:0070700	BMP receptor binding	1/422	13/18639	0.0769230769230769	3.39755741888443	0.257556977778716	0.611587187783823
GO:0071714	icosanoid transmembrane transporter activity	1/422	13/18639	0.0769230769230769	3.39755741888443	0.257556977778716	0.611587187783823
GO:0089720	caspase binding	1/422	13/18639	0.0769230769230769	3.39755741888443	0.257556977778716	0.611587187783823
GO:0016248	channel inhibitor activity	2/422	44/18639	0.0454545454545455	2.00764756570444	0.262795708282939	0.619767352981265
GO:0019205	nucleobase-containing compound kinase activity	2/422	44/18639	0.0454545454545455	2.00764756570444	0.262795708282939	0.619767352981265
GO:0141110	transporter inhibitor activity	2/422	45/18639	0.0444444444444444	1.96303317535545	0.271230533788505	0.623668731213878
GO:0004065	arylsulfatase activity	1/422	14/18639	0.0714285714285714	3.15487474610697	0.27437813934735	0.623668731213878
GO:0019763	immunoglobulin receptor activity	1/422	14/18639	0.0714285714285714	3.15487474610697	0.27437813934735	0.623668731213878
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/422	14/18639	0.0714285714285714	3.15487474610697	0.27437813934735	0.623668731213878
GO:0034236	protein kinase A catalytic subunit binding	1/422	14/18639	0.0714285714285714	3.15487474610697	0.27437813934735	0.623668731213878
GO:0043176	amine binding	1/422	14/18639	0.0714285714285714	3.15487474610697	0.27437813934735	0.623668731213878
GO:0044548	S100 protein binding	1/422	14/18639	0.0714285714285714	3.15487474610697	0.27437813934735	0.623668731213878
GO:0061783	peptidoglycan muralytic activity	1/422	14/18639	0.0714285714285714	3.15487474610697	0.27437813934735	0.623668731213878
GO:0070742	C2H2 zinc finger domain binding	1/422	14/18639	0.0714285714285714	3.15487474610697	0.27437813934735	0.623668731213878
GO:0071933	Arp2/3 complex binding	1/422	14/18639	0.0714285714285714	3.15487474610697	0.27437813934735	0.623668731213878
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/422	14/18639	0.0714285714285714	3.15487474610697	0.27437813934735	0.623668731213878
GO:0004180	carboxypeptidase activity	2/422	46/18639	0.0434782608695652	1.92035854110859	0.279662204492665	0.629467698060037
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/422	46/18639	0.0434782608695652	1.92035854110859	0.279662204492665	0.629467698060037
GO:0030291	protein serine/threonine kinase inhibitor activity	2/422	46/18639	0.0434782608695652	1.92035854110859	0.279662204492665	0.629467698060037
GO:0032182	ubiquitin-like protein binding	4/422	120/18639	0.0333333333333333	1.47227488151659	0.288681362742563	0.62995605258766
GO:0008017	microtubule binding	8/422	276/18639	0.0289855072463768	1.28023902740573	0.288852287067196	0.62995605258766
GO:0004129	cytochrome-c oxidase activity	1/422	15/18639	0.0666666666666667	2.94454976303318	0.290819074928312	0.62995605258766
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	1/422	15/18639	0.0666666666666667	2.94454976303318	0.290819074928312	0.62995605258766
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	1/422	15/18639	0.0666666666666667	2.94454976303318	0.290819074928312	0.62995605258766
GO:0005523	tropomyosin binding	1/422	15/18639	0.0666666666666667	2.94454976303318	0.290819074928312	0.62995605258766
GO:0008242	omega peptidase activity	1/422	15/18639	0.0666666666666667	2.94454976303318	0.290819074928312	0.62995605258766
GO:0008252	nucleotidase activity	1/422	15/18639	0.0666666666666667	2.94454976303318	0.290819074928312	0.62995605258766
GO:0048531	beta-1,3-galactosyltransferase activity	1/422	15/18639	0.0666666666666667	2.94454976303318	0.290819074928312	0.62995605258766
GO:0050700	CARD domain binding	1/422	15/18639	0.0666666666666667	2.94454976303318	0.290819074928312	0.62995605258766
GO:0061578	K63-linked deubiquitinase activity	1/422	15/18639	0.0666666666666667	2.94454976303318	0.290819074928312	0.62995605258766
GO:0120283	protein serine/threonine kinase binding	1/422	15/18639	0.0666666666666667	2.94454976303318	0.290819074928312	0.62995605258766
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	2/422	48/18639	0.0416666666666667	1.84034360189573	0.29649958503986	0.636816385018232
GO:0099106	ion channel regulator activity	5/422	160/18639	0.03125	1.3802577014218	0.296693228065354	0.636816385018232
GO:0008528	G protein-coupled peptide receptor activity	4/422	122/18639	0.0327868852459016	1.44813922772123	0.298846170242042	0.636816385018232
GO:0035254	glutamate receptor binding	2/422	49/18639	0.0408163265306122	1.80278556920398	0.304897514315121	0.636816385018232
GO:0060590	ATPase regulator activity	2/422	49/18639	0.0408163265306122	1.80278556920398	0.304897514315121	0.636816385018232
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	1/422	16/18639	0.0625	2.7605154028436	0.306888359205602	0.636816385018232
GO:0005159	insulin-like growth factor receptor binding	1/422	16/18639	0.0625	2.7605154028436	0.306888359205602	0.636816385018232
GO:0005521	lamin binding	1/422	16/18639	0.0625	2.7605154028436	0.306888359205602	0.636816385018232
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/422	16/18639	0.0625	2.7605154028436	0.306888359205602	0.636816385018232
GO:0016722	oxidoreductase activity, acting on metal ions	1/422	16/18639	0.0625	2.7605154028436	0.306888359205602	0.636816385018232
GO:0017070	U6 snRNA binding	1/422	16/18639	0.0625	2.7605154028436	0.306888359205602	0.636816385018232
GO:0030275	LRR domain binding	1/422	16/18639	0.0625	2.7605154028436	0.306888359205602	0.636816385018232
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/422	16/18639	0.0625	2.7605154028436	0.306888359205602	0.636816385018232
GO:0070411	I-SMAD binding	1/422	16/18639	0.0625	2.7605154028436	0.306888359205602	0.636816385018232
GO:0005006	epidermal growth factor receptor activity	2/422	50/18639	0.04	1.76672985781991	0.313276715018504	0.646123804038127
GO:0008081	phosphoric diester hydrolase activity	3/422	87/18639	0.0344827586206897	1.52304298087923	0.314993255166627	0.646123804038127
GO:0003743	translation initiation factor activity	2/422	51/18639	0.0392156862745098	1.73208809590187	0.321633736429004	0.646123804038127
GO:0016597	amino acid binding	2/422	51/18639	0.0392156862745098	1.73208809590187	0.321633736429004	0.646123804038127
GO:0004029	aldehyde dehydrogenase (NAD+) activity	1/422	17/18639	0.0588235294117647	2.5981321438528	0.322594373940888	0.646123804038127
GO:0008484	sulfuric ester hydrolase activity	1/422	17/18639	0.0588235294117647	2.5981321438528	0.322594373940888	0.646123804038127
GO:0015278	intracellularly gated calcium channel activity	1/422	17/18639	0.0588235294117647	2.5981321438528	0.322594373940888	0.646123804038127
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/422	17/18639	0.0588235294117647	2.5981321438528	0.322594373940888	0.646123804038127
GO:0016805	dipeptidase activity	1/422	17/18639	0.0588235294117647	2.5981321438528	0.322594373940888	0.646123804038127
GO:0030169	low-density lipoprotein particle binding	1/422	17/18639	0.0588235294117647	2.5981321438528	0.322594373940888	0.646123804038127
GO:0032977	membrane insertase activity	1/422	17/18639	0.0588235294117647	2.5981321438528	0.322594373940888	0.646123804038127
GO:1990226	histone methyltransferase binding	1/422	17/18639	0.0588235294117647	2.5981321438528	0.322594373940888	0.646123804038127
GO:0001653	peptide receptor activity	4/422	128/18639	0.03125	1.3802577014218	0.329560448039035	0.656271670302516
GO:0031490	chromatin DNA binding	4/422	128/18639	0.03125	1.3802577014218	0.329560448039035	0.656271670302516
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	1/422	18/18639	0.0555555555555556	2.45379146919431	0.337945312303951	0.65737974535404
GO:0017128	phospholipid scramblase activity	1/422	18/18639	0.0555555555555556	2.45379146919431	0.337945312303951	0.65737974535404
GO:0022851	GABA-gated chloride ion channel activity	1/422	18/18639	0.0555555555555556	2.45379146919431	0.337945312303951	0.65737974535404
GO:0035615	clathrin adaptor activity	1/422	18/18639	0.0555555555555556	2.45379146919431	0.337945312303951	0.65737974535404
GO:0050811	GABA receptor binding	1/422	18/18639	0.0555555555555556	2.45379146919431	0.337945312303951	0.65737974535404
GO:0005544	calcium-dependent phospholipid binding	2/422	53/18639	0.0377358490566038	1.66672628096217	0.338268258344563	0.65737974535404
GO:0008146	sulfotransferase activity	2/422	53/18639	0.0377358490566038	1.66672628096217	0.338268258344563	0.65737974535404
GO:0017046	peptide hormone binding	2/422	53/18639	0.0377358490566038	1.66672628096217	0.338268258344563	0.65737974535404
GO:0072341	modified amino acid binding	3/422	91/18639	0.032967032967033	1.45609603666476	0.339842206176114	0.65737974535404
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	4/422	130/18639	0.0307692307692308	1.35902296755377	0.33984509645018	0.65737974535404
GO:0015485	cholesterol binding	2/422	54/18639	0.037037037037037	1.63586097946288	0.346539660405742	0.65737974535404
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	2/422	54/18639	0.037037037037037	1.63586097946288	0.346539660405742	0.65737974535404
GO:0051219	phosphoprotein binding	3/422	93/18639	0.032258064516129	1.42478214340315	0.352249721501555	0.65737974535404
GO:0003756	protein disulfide isomerase activity	1/422	19/18639	0.0526315789473684	2.32464454976303	0.352949183106149	0.65737974535404
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/422	19/18639	0.0526315789473684	2.32464454976303	0.352949183106149	0.65737974535404
GO:0004890	GABA-A receptor activity	1/422	19/18639	0.0526315789473684	2.32464454976303	0.352949183106149	0.65737974535404
GO:0008301	DNA binding, bending	1/422	19/18639	0.0526315789473684	2.32464454976303	0.352949183106149	0.65737974535404
GO:0015245	fatty acid transmembrane transporter activity	1/422	19/18639	0.0526315789473684	2.32464454976303	0.352949183106149	0.65737974535404
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/422	19/18639	0.0526315789473684	2.32464454976303	0.352949183106149	0.65737974535404
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/422	19/18639	0.0526315789473684	2.32464454976303	0.352949183106149	0.65737974535404
GO:0034987	immunoglobulin receptor binding	1/422	19/18639	0.0526315789473684	2.32464454976303	0.352949183106149	0.65737974535404
GO:0046527	glucosyltransferase activity	1/422	19/18639	0.0526315789473684	2.32464454976303	0.352949183106149	0.65737974535404
GO:0097001	ceramide binding	1/422	19/18639	0.0526315789473684	2.32464454976303	0.352949183106149	0.65737974535404
GO:0140036	ubiquitin-modified protein reader activity	1/422	19/18639	0.0526315789473684	2.32464454976303	0.352949183106149	0.65737974535404
GO:0003713	transcription coactivator activity	7/422	256/18639	0.02734375	1.20772548874408	0.360331407868431	0.66932527644378
GO:0001972	retinoic acid binding	1/422	20/18639	0.05	2.20841232227488	0.367613814939082	0.675588154582195
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/422	20/18639	0.05	2.20841232227488	0.367613814939082	0.675588154582195
GO:0005326	neurotransmitter transmembrane transporter activity	1/422	20/18639	0.05	2.20841232227488	0.367613814939082	0.675588154582195
GO:0043024	ribosomal small subunit binding	1/422	20/18639	0.05	2.20841232227488	0.367613814939082	0.675588154582195
GO:0016504	peptidase activator activity	2/422	57/18639	0.0350877192982456	1.54976303317536	0.371136961768929	0.680219794877324
GO:0015631	tubulin binding	10/422	385/18639	0.025974025974026	1.14722718040254	0.374453407214585	0.680219794877324
GO:0005319	lipid transporter activity	5/422	178/18639	0.0280898876404494	1.24068107992971	0.377097263984012	0.680219794877324
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/422	21/18639	0.0476190476190476	2.10324983073798	0.381946860220553	0.680219794877324
GO:0008373	sialyltransferase activity	1/422	21/18639	0.0476190476190476	2.10324983073798	0.381946860220553	0.680219794877324
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/422	21/18639	0.0476190476190476	2.10324983073798	0.381946860220553	0.680219794877324
GO:0009975	cyclase activity	1/422	21/18639	0.0476190476190476	2.10324983073798	0.381946860220553	0.680219794877324
GO:0019200	carbohydrate kinase activity	1/422	21/18639	0.0476190476190476	2.10324983073798	0.381946860220553	0.680219794877324
GO:0036122	BMP binding	1/422	21/18639	0.0476190476190476	2.10324983073798	0.381946860220553	0.680219794877324
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/422	21/18639	0.0476190476190476	2.10324983073798	0.381946860220553	0.680219794877324
GO:0070182	DNA polymerase binding	1/422	21/18639	0.0476190476190476	2.10324983073798	0.381946860220553	0.680219794877324
GO:0140312	cargo adaptor activity	1/422	21/18639	0.0476190476190476	2.10324983073798	0.381946860220553	0.680219794877324
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	2/422	59/18639	0.0338983050847458	1.49722869306772	0.387329306824402	0.684512918198623
GO:0031593	polyubiquitin modification-dependent protein binding	2/422	59/18639	0.0338983050847458	1.49722869306772	0.387329306824402	0.684512918198623
GO:0036002	pre-mRNA binding	2/422	59/18639	0.0338983050847458	1.49722869306772	0.387329306824402	0.684512918198623
GO:0004714	transmembrane receptor protein tyrosine kinase activity	2/422	60/18639	0.0333333333333333	1.47227488151659	0.395356878432757	0.690922871748973
GO:0034062	5'-3' RNA polymerase activity	1/422	22/18639	0.0454545454545455	2.00764756570444	0.395955799149918	0.690922871748973
GO:0061133	endopeptidase activator activity	1/422	22/18639	0.0454545454545455	2.00764756570444	0.395955799149918	0.690922871748973
GO:0097747	RNA polymerase activity	1/422	22/18639	0.0454545454545455	2.00764756570444	0.395955799149918	0.690922871748973
GO:0140035	ubiquitin-like protein reader activity	1/422	22/18639	0.0454545454545455	2.00764756570444	0.395955799149918	0.690922871748973
GO:0015026	coreceptor activity	2/422	61/18639	0.0327868852459016	1.44813922772123	0.40333596213503	0.700992888664378
GO:0003887	DNA-directed DNA polymerase activity	1/422	23/18639	0.0434782608695652	1.92035854110859	0.409647943574838	0.700992888664378
GO:0016493	C-C chemokine receptor activity	1/422	23/18639	0.0434782608695652	1.92035854110859	0.409647943574838	0.700992888664378
GO:0016917	GABA receptor activity	1/422	23/18639	0.0434782608695652	1.92035854110859	0.409647943574838	0.700992888664378
GO:0043274	phospholipase binding	1/422	23/18639	0.0434782608695652	1.92035854110859	0.409647943574838	0.700992888664378
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/422	23/18639	0.0434782608695652	1.92035854110859	0.409647943574838	0.700992888664378
GO:0019903	protein phosphatase binding	4/422	144/18639	0.0277777777777778	1.22689573459716	0.41172912470167	0.700992888664378
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	12/422	484/18639	0.0247933884297521	1.09508049038424	0.415558561600183	0.700992888664378
GO:0008194	UDP-glycosyltransferase activity	4/422	145/18639	0.0275862068965517	1.21843438470338	0.416820438694093	0.700992888664378
GO:0008234	cysteine-type peptidase activity	5/422	187/18639	0.0267379679144385	1.18096915629673	0.417463653235098	0.700992888664378
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/422	24/18639	0.0416666666666667	1.84034360189573	0.423030440771412	0.700992888664378
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/422	24/18639	0.0416666666666667	1.84034360189573	0.423030440771412	0.700992888664378
GO:0004622	lysophospholipase activity	1/422	24/18639	0.0416666666666667	1.84034360189573	0.423030440771412	0.700992888664378
GO:0005540	hyaluronic acid binding	1/422	24/18639	0.0416666666666667	1.84034360189573	0.423030440771412	0.700992888664378
GO:0030552	cAMP binding	1/422	24/18639	0.0416666666666667	1.84034360189573	0.423030440771412	0.700992888664378
GO:0035035	histone acetyltransferase binding	1/422	24/18639	0.0416666666666667	1.84034360189573	0.423030440771412	0.700992888664378
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/422	24/18639	0.0416666666666667	1.84034360189573	0.423030440771412	0.700992888664378
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/422	24/18639	0.0416666666666667	1.84034360189573	0.423030440771412	0.700992888664378
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/422	24/18639	0.0416666666666667	1.84034360189573	0.423030440771412	0.700992888664378
GO:0050699	WW domain binding	1/422	24/18639	0.0416666666666667	1.84034360189573	0.423030440771412	0.700992888664378
GO:0070840	dynein complex binding	1/422	24/18639	0.0416666666666667	1.84034360189573	0.423030440771412	0.700992888664378
GO:0008013	beta-catenin binding	3/422	106/18639	0.0283018867924528	1.25004471072163	0.431746206782987	0.706573915113669
GO:0001216	DNA-binding transcription activator activity	12/422	491/18639	0.0244399185336049	1.07946834490015	0.434948492659672	0.706573915113669
GO:0004709	MAP kinase kinase kinase activity	1/422	25/18639	0.04	1.76672985781991	0.436110277139634	0.706573915113669
GO:0005251	delayed rectifier potassium channel activity	1/422	25/18639	0.04	1.76672985781991	0.436110277139634	0.706573915113669
GO:0015662	P-type ion transporter activity	1/422	25/18639	0.04	1.76672985781991	0.436110277139634	0.706573915113669
GO:0042974	nuclear retinoic acid receptor binding	1/422	25/18639	0.04	1.76672985781991	0.436110277139634	0.706573915113669
GO:0140358	P-type transmembrane transporter activity	1/422	25/18639	0.04	1.76672985781991	0.436110277139634	0.706573915113669
GO:0001217	DNA-binding transcription repressor activity	7/422	278/18639	0.0251798561151079	1.11215009035426	0.441689421065716	0.706573915113669
GO:0019842	vitamin binding	4/422	150/18639	0.0266666666666667	1.17781990521327	0.442113690483979	0.706573915113669
GO:0005496	steroid binding	3/422	108/18639	0.0277777777777778	1.22689573459716	0.443694445157283	0.706573915113669
GO:0001637	G protein-coupled chemoattractant receptor activity	1/422	26/18639	0.0384615384615385	1.69877870944222	0.448894281816065	0.706573915113669
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/422	26/18639	0.0384615384615385	1.69877870944222	0.448894281816065	0.706573915113669
GO:0004435	phosphatidylinositol phospholipase C activity	1/422	26/18639	0.0384615384615385	1.69877870944222	0.448894281816065	0.706573915113669
GO:0004950	chemokine receptor activity	1/422	26/18639	0.0384615384615385	1.69877870944222	0.448894281816065	0.706573915113669
GO:0005112	Notch binding	1/422	26/18639	0.0384615384615385	1.69877870944222	0.448894281816065	0.706573915113669
GO:0005160	transforming growth factor beta receptor binding	1/422	26/18639	0.0384615384615385	1.69877870944222	0.448894281816065	0.706573915113669
GO:0008157	protein phosphatase 1 binding	1/422	26/18639	0.0384615384615385	1.69877870944222	0.448894281816065	0.706573915113669
GO:0030247	polysaccharide binding	1/422	26/18639	0.0384615384615385	1.69877870944222	0.448894281816065	0.706573915113669
GO:0034237	protein kinase A regulatory subunit binding	1/422	26/18639	0.0384615384615385	1.69877870944222	0.448894281816065	0.706573915113669
GO:0050750	low-density lipoprotein particle receptor binding	1/422	26/18639	0.0384615384615385	1.69877870944222	0.448894281816065	0.706573915113669
GO:0070006	metalloaminopeptidase activity	1/422	26/18639	0.0384615384615385	1.69877870944222	0.448894281816065	0.706573915113669
GO:0070412	R-SMAD binding	1/422	26/18639	0.0384615384615385	1.69877870944222	0.448894281816065	0.706573915113669
GO:0004222	metalloendopeptidase activity	3/422	110/18639	0.0272727272727273	1.20458853942266	0.455543279687412	0.714842800385739
GO:0001671	ATPase activator activity	1/422	27/18639	0.037037037037037	1.63586097946288	0.461389130205557	0.714842800385739
GO:0004364	glutathione transferase activity	1/422	27/18639	0.037037037037037	1.63586097946288	0.461389130205557	0.714842800385739
GO:0005044	scavenger receptor activity	1/422	27/18639	0.037037037037037	1.63586097946288	0.461389130205557	0.714842800385739
GO:0005385	zinc ion transmembrane transporter activity	1/422	27/18639	0.037037037037037	1.63586097946288	0.461389130205557	0.714842800385739
GO:0008320	protein transmembrane transporter activity	1/422	27/18639	0.037037037037037	1.63586097946288	0.461389130205557	0.714842800385739
GO:0035255	ionotropic glutamate receptor binding	1/422	27/18639	0.037037037037037	1.63586097946288	0.461389130205557	0.714842800385739
GO:0005200	structural constituent of cytoskeleton	3/422	112/18639	0.0267857142857143	1.18307802979012	0.467285420098314	0.722358445834306
GO:0008028	monocarboxylic acid transmembrane transporter activity	2/422	70/18639	0.0285714285714286	1.26194989844279	0.472683888916006	0.725628672010643
GO:0016782	transferase activity, transferring sulphur-containing groups	2/422	70/18639	0.0285714285714286	1.26194989844279	0.472683888916006	0.725628672010643
GO:0005242	inward rectifier potassium channel activity	1/422	28/18639	0.0357142857142857	1.57743737305349	0.473601347433864	0.725628672010643
GO:0141052	histone H3 demethylase activity	1/422	28/18639	0.0357142857142857	1.57743737305349	0.473601347433864	0.725628672010643
GO:0004629	phospholipase C activity	1/422	29/18639	0.0344827586206897	1.52304298087923	0.485537311722882	0.739000622027558
GO:0035250	UDP-galactosyltransferase activity	1/422	29/18639	0.0344827586206897	1.52304298087923	0.485537311722882	0.739000622027558
GO:0099604	ligand-gated calcium channel activity	1/422	29/18639	0.0344827586206897	1.52304298087923	0.485537311722882	0.739000622027558
GO:0003714	transcription corepressor activity	5/422	204/18639	0.0245098039215686	1.08255505993867	0.492214668335546	0.747517221582115
GO:0001965	G-protein alpha-subunit binding	1/422	30/18639	0.0333333333333333	1.47227488151659	0.497203257690262	0.748512965280983
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/422	30/18639	0.0333333333333333	1.47227488151659	0.497203257690262	0.748512965280983
GO:0032452	histone demethylase activity	1/422	30/18639	0.0333333333333333	1.47227488151659	0.497203257690262	0.748512965280983
GO:0035925	mRNA 3'-UTR AU-rich region binding	1/422	30/18639	0.0333333333333333	1.47227488151659	0.497203257690262	0.748512965280983
GO:0031491	nucleosome binding	2/422	74/18639	0.027027027027027	1.19373639041885	0.501918497152117	0.753968872895897
GO:0005184	neuropeptide hormone activity	1/422	31/18639	0.032258064516129	1.42478214340315	0.508605279575087	0.757152273718751
GO:0070325	lipoprotein particle receptor binding	1/422	31/18639	0.032258064516129	1.42478214340315	0.508605279575087	0.757152273718751
GO:0072349	modified amino acid transmembrane transporter activity	1/422	31/18639	0.032258064516129	1.42478214340315	0.508605279575087	0.757152273718751
GO:0140457	protein demethylase activity	1/422	31/18639	0.032258064516129	1.42478214340315	0.508605279575087	0.757152273718751
GO:0005261	monoatomic cation channel activity	8/422	341/18639	0.0234604105571848	1.03620519520229	0.509516363645758	0.757152273718751
GO:0017022	myosin binding	2/422	76/18639	0.0263157894736842	1.16232227488152	0.51613953761458	0.757693649924809
GO:0008378	galactosyltransferase activity	1/422	32/18639	0.03125	1.3802577014218	0.519749334391258	0.757693649924809
GO:0022884	macromolecule transmembrane transporter activity	1/422	32/18639	0.03125	1.3802577014218	0.519749334391258	0.757693649924809
GO:0031369	translation initiation factor binding	1/422	32/18639	0.03125	1.3802577014218	0.519749334391258	0.757693649924809
GO:0042910	xenobiotic transmembrane transporter activity	1/422	32/18639	0.03125	1.3802577014218	0.519749334391258	0.757693649924809
GO:0071813	lipoprotein particle binding	1/422	32/18639	0.03125	1.3802577014218	0.519749334391258	0.757693649924809
GO:0071814	protein-lipid complex binding	1/422	32/18639	0.03125	1.3802577014218	0.519749334391258	0.757693649924809
GO:0120015	sterol transfer activity	1/422	32/18639	0.03125	1.3802577014218	0.519749334391258	0.757693649924809
GO:0160041	neuropeptide activity	1/422	32/18639	0.03125	1.3802577014218	0.519749334391258	0.757693649924809
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	3/422	122/18639	0.0245901639344262	1.08610442079093	0.524174728168213	0.760934321773604
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	3/422	122/18639	0.0245901639344262	1.08610442079093	0.524174728168213	0.760934321773604
GO:0019199	transmembrane receptor protein kinase activity	2/422	78/18639	0.0256410256410256	1.13251913962814	0.530089058160251	0.763902292295953
GO:0042923	neuropeptide binding	1/422	33/18639	0.0303030303030303	1.33843171046963	0.530641245010213	0.763902292295953
GO:0071889	14-3-3 protein binding	1/422	33/18639	0.0303030303030303	1.33843171046963	0.530641245010213	0.763902292295953
GO:0140416	transcription regulator inhibitor activity	1/422	33/18639	0.0303030303030303	1.33843171046963	0.530641245010213	0.763902292295953
GO:0005267	potassium channel activity	3/422	124/18639	0.0241935483870968	1.06858660755236	0.535150575734507	0.768792199236059
GO:0008376	acetylgalactosaminyltransferase activity	1/422	34/18639	0.0294117647058824	1.2990660719264	0.541286703174552	0.76960722611855
GO:0016831	carboxy-lyase activity	1/422	34/18639	0.0294117647058824	1.2990660719264	0.541286703174552	0.76960722611855
GO:0019825	oxygen binding	1/422	34/18639	0.0294117647058824	1.2990660719264	0.541286703174552	0.76960722611855
GO:0030332	cyclin binding	1/422	34/18639	0.0294117647058824	1.2990660719264	0.541286703174552	0.76960722611855
GO:0090482	vitamin transmembrane transporter activity	1/422	34/18639	0.0294117647058824	1.2990660719264	0.541286703174552	0.76960722611855
GO:0000049	tRNA binding	2/422	80/18639	0.025	1.10420616113744	0.543762820836689	0.771540265293947
GO:0034061	DNA polymerase activity	1/422	35/18639	0.0285714285714286	1.26194989844279	0.551691272444121	0.777997284201812
GO:0043015	gamma-tubulin binding	1/422	35/18639	0.0285714285714286	1.26194989844279	0.551691272444121	0.777997284201812
GO:0061631	ubiquitin conjugating enzyme activity	1/422	35/18639	0.0285714285714286	1.26194989844279	0.551691272444121	0.777997284201812
GO:0005244	voltage-gated monoatomic ion channel activity	4/422	173/18639	0.023121387283237	1.02123113168781	0.55305263180359	0.778328652904849
GO:0004190	aspartic-type endopeptidase activity	1/422	36/18639	0.0277777777777778	1.22689573459716	0.56186039107606	0.786332682557134
GO:0005484	SNAP receptor activity	1/422	36/18639	0.0277777777777778	1.22689573459716	0.56186039107606	0.786332682557134
GO:0022832	voltage-gated channel activity	4/422	175/18639	0.0228571428571429	1.00955991875423	0.562153900409876	0.786332682557134
GO:0030165	PDZ domain binding	2/422	83/18639	0.0240963855421687	1.06429509507223	0.563749396003494	0.786614220264217
GO:0016757	glycosyltransferase activity	6/422	267/18639	0.0224719101123595	0.992544863943767	0.564631914979814	0.786614220264217
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	6/422	268/18639	0.0223880597014925	0.988841338332036	0.568293561764157	0.788649437154965
GO:0051117	ATPase binding	2/422	84/18639	0.0238095238095238	1.05162491536899	0.570270650884895	0.788649437154965
GO:0030280	structural constituent of skin epidermis	1/422	37/18639	0.027027027027027	1.19373639041885	0.571799374840286	0.788649437154965
GO:0030551	cyclic nucleotide binding	1/422	37/18639	0.027027027027027	1.19373639041885	0.571799374840286	0.788649437154965
GO:0070001	aspartic-type peptidase activity	1/422	37/18639	0.027027027027027	1.19373639041885	0.571799374840286	0.788649437154965
GO:0005543	phospholipid binding	11/422	497/18639	0.0221327967806841	0.977566822737372	0.573509310002664	0.789432137872194
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	3/422	132/18639	0.0227272727272727	1.00382378285222	0.577573158430561	0.793445432356894
GO:0000146	microfilament motor activity	1/422	38/18639	0.0263157894736842	1.16232227488152	0.581513419771874	0.795694600123495
GO:0043531	ADP binding	1/422	38/18639	0.0263157894736842	1.16232227488152	0.581513419771874	0.795694600123495
GO:0022804	active transmembrane transporter activity	10/422	457/18639	0.0218818380743982	0.966482416750495	0.588499267310653	0.803662042908422
GO:0000217	DNA secondary structure binding	1/422	39/18639	0.0256410256410256	1.13251913962814	0.591007604861722	0.803909950707579
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	1/422	39/18639	0.0256410256410256	1.13251913962814	0.591007604861722	0.803909950707579
GO:0099094	ligand-gated monoatomic cation channel activity	3/422	136/18639	0.0220588235294118	0.974299553944801	0.597852990616623	0.808573575494444
GO:0005085	guanyl-nucleotide exchange factor activity	5/422	230/18639	0.0217391304347826	0.960179270554296	0.598678847927901	0.808573575494444
GO:0004177	aminopeptidase activity	1/422	40/18639	0.025	1.10420616113744	0.600286894686903	0.808573575494444
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/422	40/18639	0.025	1.10420616113744	0.600286894686903	0.808573575494444
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	1/422	40/18639	0.025	1.10420616113744	0.600286894686903	0.808573575494444
GO:0001530	lipopolysaccharide binding	1/422	41/18639	0.024390243902439	1.07727430354872	0.609356141982033	0.812605649726694
GO:0017080	sodium channel regulator activity	1/422	41/18639	0.024390243902439	1.07727430354872	0.609356141982033	0.812605649726694
GO:0042287	MHC protein binding	1/422	41/18639	0.024390243902439	1.07727430354872	0.609356141982033	0.812605649726694
GO:0061650	ubiquitin-like protein conjugating enzyme activity	1/422	41/18639	0.024390243902439	1.07727430354872	0.609356141982033	0.812605649726694
GO:0140318	protein transporter activity	1/422	41/18639	0.024390243902439	1.07727430354872	0.609356141982033	0.812605649726694
GO:0015276	ligand-gated monoatomic ion channel activity	4/422	186/18639	0.021505376344086	0.949854762268766	0.610336226061004	0.812605649726694
GO:0140767	enzyme-substrate adaptor activity	3/422	139/18639	0.0215827338129496	0.953271506017935	0.612639989444509	0.814104293665684
GO:0004713	protein tyrosine kinase activity	3/422	140/18639	0.0214285714285714	0.946462423832092	0.617487302085756	0.817493285001601
GO:0048487	beta-tubulin binding	1/422	42/18639	0.0238095238095238	1.05162491536899	0.618220090152997	0.817493285001601
GO:0022834	ligand-gated channel activity	4/422	188/18639	0.0212765957446809	0.93974992437229	0.618739490674149	0.817493285001601
GO:0005245	voltage-gated calcium channel activity	1/422	43/18639	0.0232558139534884	1.02716852198832	0.626883375734297	0.82528929499458
GO:0019902	phosphatase binding	4/422	190/18639	0.0210526315789474	0.929857819905213	0.627028769713682	0.82528929499458
GO:0022843	voltage-gated monoatomic cation channel activity	3/422	143/18639	0.020979020979021	0.926606568786664	0.631781882141156	0.829919124341761
GO:0001046	core promoter sequence-specific DNA binding	1/422	44/18639	0.0227272727272727	1.00382378285222	0.635350530791305	0.829919124341761
GO:0001223	transcription coactivator binding	1/422	44/18639	0.0227272727272727	1.00382378285222	0.635350530791305	0.829919124341761
GO:0043014	alpha-tubulin binding	1/422	44/18639	0.0227272727272727	1.00382378285222	0.635350530791305	0.829919124341761
GO:0004867	serine-type endopeptidase inhibitor activity	2/422	95/18639	0.0210526315789474	0.929857819905213	0.637318537230484	0.83091907401182
GO:0004715	non-membrane spanning protein tyrosine kinase activity	1/422	45/18639	0.0222222222222222	0.981516587677725	0.643625985268641	0.834419429307
GO:0046915	transition metal ion transmembrane transporter activity	1/422	45/18639	0.0222222222222222	0.981516587677725	0.643625985268641	0.834419429307
GO:0140303	intramembrane lipid transporter activity	1/422	45/18639	0.0222222222222222	0.981516587677725	0.643625985268641	0.834419429307
GO:0015085	calcium ion transmembrane transporter activity	3/422	147/18639	0.0204081632653061	0.901392784601992	0.650259743391015	0.840275857440992
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/422	46/18639	0.0217391304347826	0.960179270554296	0.651714069285885	0.840275857440992
GO:0005249	voltage-gated potassium channel activity	2/422	98/18639	0.0204081632653061	0.901392784601992	0.654119949684469	0.840275857440992
GO:0042626	ATPase-coupled transmembrane transporter activity	2/422	98/18639	0.0204081632653061	0.901392784601992	0.654119949684469	0.840275857440992
GO:0016758	hexosyltransferase activity	4/422	197/18639	0.0203045685279188	0.896817186710612	0.655126429179409	0.840275857440992
GO:0001784	phosphotyrosine residue binding	1/422	47/18639	0.0212765957446809	0.93974992437229	0.6596190153818	0.840275857440992
GO:0099095	ligand-gated monoatomic anion channel activity	1/422	47/18639	0.0212765957446809	0.93974992437229	0.6596190153818	0.840275857440992
GO:0016829	lyase activity	4/422	200/18639	0.02	0.883364928909953	0.666725688103774	0.840275857440992
GO:0008188	neuropeptide receptor activity	1/422	48/18639	0.0208333333333333	0.920171800947867	0.667344960708225	0.840275857440992
GO:0038187	pattern recognition receptor activity	1/422	48/18639	0.0208333333333333	0.920171800947867	0.667344960708225	0.840275857440992
GO:0001222	transcription corepressor binding	1/422	49/18639	0.0204081632653061	0.901392784601992	0.674895949174748	0.840275857440992
GO:0005004	GPI-linked ephrin receptor activity	1/422	49/18639	0.0204081632653061	0.901392784601992	0.674895949174748	0.840275857440992
GO:0005008	hepatocyte growth factor receptor activity	1/422	49/18639	0.0204081632653061	0.901392784601992	0.674895949174748	0.840275857440992
GO:0005009	insulin receptor activity	1/422	49/18639	0.0204081632653061	0.901392784601992	0.674895949174748	0.840275857440992
GO:0005011	macrophage colony-stimulating factor receptor activity	1/422	49/18639	0.0204081632653061	0.901392784601992	0.674895949174748	0.840275857440992
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/422	49/18639	0.0204081632653061	0.901392784601992	0.674895949174748	0.840275857440992
GO:0005020	stem cell factor receptor activity	1/422	49/18639	0.0204081632653061	0.901392784601992	0.674895949174748	0.840275857440992
GO:0008288	boss receptor activity	1/422	49/18639	0.0204081632653061	0.901392784601992	0.674895949174748	0.840275857440992
GO:0016763	pentosyltransferase activity	1/422	49/18639	0.0204081632653061	0.901392784601992	0.674895949174748	0.840275857440992
GO:0036332	placental growth factor receptor activity	1/422	49/18639	0.0204081632653061	0.901392784601992	0.674895949174748	0.840275857440992
GO:0038062	protein tyrosine kinase collagen receptor activity	1/422	49/18639	0.0204081632653061	0.901392784601992	0.674895949174748	0.840275857440992
GO:0060175	brain-derived neurotrophic factor receptor activity	1/422	49/18639	0.0204081632653061	0.901392784601992	0.674895949174748	0.840275857440992
GO:0005007	fibroblast growth factor receptor activity	1/422	50/18639	0.02	0.883364928909953	0.682275933545283	0.844746002205563
GO:0005017	platelet-derived growth factor receptor activity	1/422	50/18639	0.02	0.883364928909953	0.682275933545283	0.844746002205563
GO:0005019	platelet-derived growth factor beta-receptor activity	1/422	50/18639	0.02	0.883364928909953	0.682275933545283	0.844746002205563
GO:0005216	monoatomic ion channel activity	9/422	448/18639	0.0200892857142857	0.887308522342586	0.688588530835548	0.844746002205563
GO:0005010	insulin-like growth factor receptor activity	1/422	51/18639	0.0196078431372549	0.866044047950934	0.689488777487609	0.844746002205563
GO:0005021	vascular endothelial growth factor receptor activity	1/422	51/18639	0.0196078431372549	0.866044047950934	0.689488777487609	0.844746002205563
GO:0005030	neurotrophin receptor activity	1/422	51/18639	0.0196078431372549	0.866044047950934	0.689488777487609	0.844746002205563
GO:0016830	carbon-carbon lyase activity	1/422	51/18639	0.0196078431372549	0.866044047950934	0.689488777487609	0.844746002205563
GO:0030544	Hsp70 protein binding	1/422	51/18639	0.0196078431372549	0.866044047950934	0.689488777487609	0.844746002205563
GO:0000149	SNARE binding	2/422	106/18639	0.0188679245283019	0.833363140481087	0.695888632729372	0.849535566766383
GO:0004497	monooxygenase activity	2/422	106/18639	0.0188679245283019	0.833363140481087	0.695888632729372	0.849535566766383
GO:0004864	protein phosphatase inhibitor activity	1/422	53/18639	0.0188679245283019	0.833363140481087	0.703428065254472	0.849535566766383
GO:0005003	ephrin receptor activity	1/422	53/18639	0.0188679245283019	0.833363140481087	0.703428065254472	0.849535566766383
GO:0005005	transmembrane-ephrin receptor activity	1/422	53/18639	0.0188679245283019	0.833363140481087	0.703428065254472	0.849535566766383
GO:0038064	collagen receptor activity	1/422	53/18639	0.0188679245283019	0.833363140481087	0.703428065254472	0.849535566766383
GO:0051018	protein kinase A binding	1/422	53/18639	0.0188679245283019	0.833363140481087	0.703428065254472	0.849535566766383
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/422	53/18639	0.0188679245283019	0.833363140481087	0.703428065254472	0.849535566766383
GO:0004843	cysteine-type deubiquitinase activity	2/422	108/18639	0.0185185185185185	0.817930489731438	0.705657056131514	0.849535566766383
GO:0015079	potassium ion transmembrane transporter activity	3/422	160/18639	0.01875	0.828154620853081	0.705692352133001	0.849535566766383
GO:0017069	snRNA binding	1/422	54/18639	0.0185185185185185	0.817930489731438	0.710161808742184	0.849539276976805
GO:0051287	NAD binding	1/422	54/18639	0.0185185185185185	0.817930489731438	0.710161808742184	0.849539276976805
GO:0004620	phospholipase activity	2/422	109/18639	0.018348623853211	0.81042654028436	0.71044257577085	0.849539276976805
GO:0003730	mRNA 3'-UTR binding	5/422	262/18639	0.0190839694656489	0.84290546651713	0.710613172348181	0.849539276976805
GO:0019212	phosphatase inhibitor activity	1/422	56/18639	0.0178571428571429	0.788718686526743	0.723175131127609	0.861575888981341
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/422	56/18639	0.0178571428571429	0.788718686526743	0.723175131127609	0.861575888981341
GO:0022836	gated channel activity	6/422	318/18639	0.0188679245283019	0.833363140481087	0.729375847759078	0.866078892033039
GO:0004601	peroxidase activity	1/422	57/18639	0.0175438596491228	0.774881516587678	0.729461527009014	0.866078892033039
GO:0016887	ATP hydrolysis activity	8/422	417/18639	0.0191846522781775	0.847352449793719	0.731037134431246	0.866460823142351
GO:0035401	histone H3Y41 kinase activity	2/422	115/18639	0.0173913043478261	0.768143416443437	0.737804798403218	0.870005316888436
GO:0101005	deubiquitinase activity	2/422	115/18639	0.0173913043478261	0.768143416443437	0.737804798403218	0.870005316888436
GO:0140801	histone H2AXY142 kinase activity	2/422	115/18639	0.0173913043478261	0.768143416443437	0.737804798403218	0.870005316888436
GO:0045309	protein phosphorylated amino acid binding	1/422	59/18639	0.0169491525423729	0.748614346533858	0.741610258091003	0.871518177450481
GO:0070063	RNA polymerase binding	1/422	59/18639	0.0169491525423729	0.748614346533858	0.741610258091003	0.871518177450481
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	1/422	61/18639	0.0163934426229508	0.724069613860617	0.753214676062911	0.883260173197648
GO:0140030	modification-dependent protein binding	3/422	173/18639	0.0173410404624277	0.765923348765855	0.754158469155735	0.883260173197648
GO:0022824	transmitter-gated monoatomic ion channel activity	1/422	63/18639	0.0158730158730159	0.701083276912661	0.76429911305969	0.892112647169334
GO:0022835	transmitter-gated channel activity	1/422	63/18639	0.0158730158730159	0.701083276912661	0.76429911305969	0.892112647169334
GO:0038024	cargo receptor activity	1/422	65/18639	0.0153846153846154	0.679511483776887	0.77488681598395	0.901425572129478
GO:0120013	lipid transfer activity	1/422	65/18639	0.0153846153846154	0.679511483776887	0.77488681598395	0.901425572129478
GO:0016500	protein-hormone receptor activity	1/422	67/18639	0.0149253731343284	0.659227558888024	0.784999994797815	0.911226248649421
GO:0019783	ubiquitin-like protein peptidase activity	2/422	127/18639	0.015748031496063	0.695562936149569	0.785949123292409	0.911226248649421
GO:0005548	phospholipid transporter activity	1/422	68/18639	0.0147058823529412	0.6495330359632	0.789885306137215	0.912727000904373
GO:0030145	manganese ion binding	1/422	68/18639	0.0147058823529412	0.6495330359632	0.789885306137215	0.912727000904373
GO:0002039	p53 binding	1/422	69/18639	0.0144927536231884	0.640119513702864	0.79465986867074	0.912972933709548
GO:0008080	N-acetyltransferase activity	1/422	69/18639	0.0144927536231884	0.640119513702864	0.79465986867074	0.912972933709548
GO:0098960	postsynaptic neurotransmitter receptor activity	1/422	69/18639	0.0144927536231884	0.640119513702864	0.79465986867074	0.912972933709548
GO:0016298	lipase activity	2/422	130/18639	0.0153846153846154	0.679511483776887	0.796704311182138	0.912972933709548
GO:0016798	hydrolase activity, acting on glycosyl bonds	2/422	130/18639	0.0153846153846154	0.679511483776887	0.796704311182138	0.912972933709548
GO:0097110	scaffold protein binding	1/422	70/18639	0.0142857142857143	0.630974949221395	0.79932618721791	0.913926687316994
GO:0005262	calcium channel activity	2/422	131/18639	0.0152671755725191	0.674324373213704	0.800181831876674	0.913926687316994
GO:0140597	protein carrier chaperone	3/422	188/18639	0.0159574468085106	0.704812443279217	0.801883137977554	0.91435849561467
GO:0140299	molecular sensor activity	1/422	71/18639	0.0140845070422535	0.6220879781056	0.803886710078271	0.915132976382348
GO:0004521	RNA endonuclease activity	1/422	73/18639	0.0136986301369863	0.605044471856132	0.812699886942522	0.922127457926573
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/422	73/18639	0.0136986301369863	0.605044471856132	0.812699886942522	0.922127457926573
GO:0016779	nucleotidyltransferase activity	2/422	136/18639	0.0147058823529412	0.6495330359632	0.816789855644285	0.925248836475739
GO:0003725	double-stranded RNA binding	1/422	75/18639	0.0133333333333333	0.588909952606635	0.821117902901124	0.927111880563198
GO:0019003	GDP binding	1/422	75/18639	0.0133333333333333	0.588909952606635	0.821117902901124	0.927111880563198
GO:0003724	RNA helicase activity	1/422	77/18639	0.012987012987013	0.573613590201268	0.829158435787578	0.934663098090076
GO:0008186	ATP-dependent activity, acting on RNA	1/422	79/18639	0.0126582278481013	0.559091727158198	0.836838374402269	0.940252547499135
GO:0016835	carbon-oxygen lyase activity	1/422	79/18639	0.0126582278481013	0.559091727158198	0.836838374402269	0.940252547499135
GO:0008168	methyltransferase activity	3/422	204/18639	0.0147058823529412	0.6495330359632	0.843982066816284	0.943890182640915
GO:0051020	GTPase binding	5/422	315/18639	0.0158730158730159	0.701083276912661	0.844053883514812	0.943890182640915
GO:0015101	organic cation transmembrane transporter activity	1/422	81/18639	0.0123456790123457	0.545286993154292	0.844173853649907	0.943890182640915
GO:0015293	symporter activity	2/422	146/18639	0.0136986301369863	0.605044471856132	0.846346719565736	0.944790926041879
GO:0005254	chloride channel activity	1/422	83/18639	0.0120481927710843	0.532147547536116	0.851180288115787	0.946896379263064
GO:0004527	exonuclease activity	1/422	84/18639	0.0119047619047619	0.525812457684496	0.8545647415764	0.946896379263064
GO:0051015	actin filament binding	3/422	209/18639	0.0143540669856459	0.633993968117191	0.85544799640982	0.946896379263064
GO:0000510	H3-H4 histone complex chaperone activity	2/422	151/18639	0.0132450331125828	0.585009886695333	0.859442385544409	0.946896379263064
GO:0140584	chromatin extrusion motor activity	2/422	151/18639	0.0132450331125828	0.585009886695333	0.859442385544409	0.946896379263064
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	2/422	151/18639	0.0132450331125828	0.585009886695333	0.859442385544409	0.946896379263064
GO:0140849	ATP-dependent H2AZ histone chaperone activity	2/422	151/18639	0.0132450331125828	0.585009886695333	0.859442385544409	0.946896379263064
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	1/422	86/18639	0.0116279069767442	0.513584260994159	0.861105014123606	0.946896379263064
GO:0015616	DNA translocase activity	2/422	152/18639	0.0131578947368421	0.581161137440758	0.861936067375496	0.946896379263064
GO:0140674	ATP-dependent histone chaperone activity	2/422	152/18639	0.0131578947368421	0.581161137440758	0.861936067375496	0.946896379263064
GO:0061775	cohesin loader activity	2/422	153/18639	0.0130718954248366	0.577362698633956	0.864389235341967	0.948084066065554
GO:0016741	transferase activity, transferring one-carbon groups	3/422	215/18639	0.013953488372093	0.61630111319299	0.868230947752772	0.95078856560565
GO:0140793	histone H2AXY142 phosphatase activity	1/422	90/18639	0.0111111111111111	0.490758293838863	0.873318338179048	0.95484647417994
GO:0140658	ATP-dependent chromatin remodeler activity	2/422	158/18639	0.0126582278481013	0.559091727158198	0.876066496972773	0.954975532252504
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	1/422	91/18639	0.010989010989011	0.485365345554919	0.876200415988549	0.954975532252504
GO:0003689	DNA clamp loader activity	2/422	160/18639	0.0125	0.55210308056872	0.8804727551586	0.958120746164713
GO:0016410	N-acyltransferase activity	1/422	94/18639	0.0106382978723404	0.469874962186145	0.884460039388785	0.960082478223448
GO:0031267	small GTPase binding	4/422	283/18639	0.0141342756183746	0.624286168840956	0.886273499755245	0.960082478223448
GO:0046873	metal ion transmembrane transporter activity	7/422	450/18639	0.0155555555555556	0.687061611374408	0.887024054010681	0.960082478223448
GO:0140713	histone chaperone activity	2/422	164/18639	0.0121951219512195	0.538637151774361	0.888854627974994	0.960082478223448
GO:0016407	acetyltransferase activity	1/422	96/18639	0.0104166666666667	0.460085900473934	0.889658679919207	0.960082478223448
GO:0030594	neurotransmitter receptor activity	1/422	97/18639	0.0103092783505155	0.4553427468608	0.892169818196406	0.960082478223448
GO:0008170	N-methyltransferase activity	1/422	98/18639	0.0102040816326531	0.450696392300996	0.894623940552199	0.960082478223448
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	2/422	167/18639	0.0119760479041916	0.528961035275421	0.894780196781332	0.960082478223448
GO:0016874	ligase activity	2/422	167/18639	0.0119760479041916	0.528961035275421	0.894780196781332	0.960082478223448
GO:0015171	amino acid transmembrane transporter activity	1/422	102/18639	0.00980392156862745	0.433022023975467	0.903895667925946	0.968359545018339
GO:0005253	monoatomic anion channel activity	1/422	103/18639	0.00970873786407767	0.428817926655317	0.906083509978881	0.969200782345831
GO:0042578	phosphoric ester hydrolase activity	5/422	363/18639	0.0137741046831956	0.608378050213466	0.916755516051597	0.979100558874271
GO:0042393	histone binding	3/422	247/18639	0.0121457489878543	0.5364564345607	0.920905698866953	0.981548784623384
GO:1902936	phosphatidylinositol bisphosphate binding	1/422	111/18639	0.00900900900900901	0.397912130139618	0.921888800608649	0.981548784623384
GO:0140104	molecular carrier activity	3/422	249/18639	0.0120481927710843	0.532147547536116	0.923454276863056	0.981702931249803
GO:0046943	carboxylic acid transmembrane transporter activity	2/422	188/18639	0.0106382978723404	0.469874962186145	0.928705190518837	0.984151935974073
GO:0017124	SH3 domain binding	1/422	115/18639	0.00869565217391304	0.384071708221718	0.928766230929021	0.984151935974073
GO:0005342	organic acid transmembrane transporter activity	2/422	189/18639	0.0105820105820106	0.467388851275107	0.930030700710666	0.984151935974073
GO:0004540	RNA nuclease activity	1/422	121/18639	0.00826446280991736	0.36502683012808	0.937966190296334	0.989518530526362
GO:0015108	chloride transmembrane transporter activity	1/422	121/18639	0.00826446280991736	0.36502683012808	0.937966190296334	0.989518530526362
GO:0008514	organic anion transmembrane transporter activity	3/422	269/18639	0.0111524163568773	0.492582674113356	0.94510463244802	0.993273867986115
GO:0004519	endonuclease activity	1/422	127/18639	0.0078740157480315	0.347781468074784	0.945980408585938	0.993273867986115
GO:0140097	catalytic activity, acting on DNA	4/422	336/18639	0.0119047619047619	0.525812457684496	0.948280247115084	0.993273867986115
GO:0035591	signaling adaptor activity	1/422	129/18639	0.00775193798449612	0.342389507329439	0.94841526566844	0.993273867986115
GO:0019001	guanyl nucleotide binding	5/422	400/18639	0.0125	0.55210308056872	0.950515409271288	0.993273867986115
GO:0032561	guanyl ribonucleotide binding	5/422	400/18639	0.0125	0.55210308056872	0.950515409271288	0.993273867986115
GO:0004518	nuclease activity	2/422	209/18639	0.00956937799043062	0.422662645411461	0.952117105285498	0.993273867986115
GO:0008094	ATP-dependent activity, acting on DNA	2/422	210/18639	0.00952380952380952	0.420649966147597	0.953025433393334	0.993273867986115
GO:0140789	histone phosphatase activity	1/422	136/18639	0.00735294117647059	0.3247665179816	0.956106661496144	0.994984492611198
GO:0015291	secondary active transmembrane transporter activity	3/422	287/18639	0.0104529616724739	0.461688987235167	0.959588668185175	0.997106420625498
GO:0030695	GTPase regulator activity	6/422	489/18639	0.0122699386503067	0.541941674177885	0.967193076959487	0.999872057938209
GO:0008509	monoatomic anion transmembrane transporter activity	1/422	149/18639	0.00671140939597315	0.296431184197971	0.967483804118125	0.999872057938209
GO:0060589	nucleoside-triphosphatase regulator activity	6/422	490/18639	0.0122448979591837	0.540835670761195	0.967653595558268	0.999872057938209
GO:0046982	protein heterodimerization activity	4/422	369/18639	0.010840108401084	0.478788579354988	0.969270967967383	0.999872057938209
GO:0003774	cytoskeletal motor activity	1/422	153/18639	0.0065359477124183	0.288681349316978	0.970352428706571	0.999872057938209
GO:0004386	helicase activity	1/422	155/18639	0.00645161290322581	0.28495642868063	0.971690609118214	0.999872057938209
GO:0005525	GTP binding	4/422	378/18639	0.0105820105820106	0.467388851275107	0.973430844337232	0.999872057938209
GO:0015103	inorganic anion transmembrane transporter activity	1/422	165/18639	0.00606060606060606	0.267686342093925	0.977529921249288	0.999872057938209
GO:0003924	GTPase activity	3/422	331/18639	0.00906344410876133	0.400316433040764	0.981349891892726	0.999872057938209
GO:0004721	phosphoprotein phosphatase activity	1/422	175/18639	0.00571428571428571	0.252389979688558	0.982167028660695	0.999872057938209
GO:1901981	phosphatidylinositol phosphate binding	1/422	185/18639	0.00540540540540541	0.238747278083771	0.985848977677882	0.999872057938209
GO:0016791	phosphatase activity	2/422	273/18639	0.00732600732600733	0.323576897036613	0.986355068380207	0.999872057938209
GO:0035091	phosphatidylinositol binding	2/422	284/18639	0.00704225352112676	0.3110439890528	0.989060270050292	0.999872057938209
GO:0140098	catalytic activity, acting on RNA	3/422	387/18639	0.00775193798449612	0.342389507329439	0.993313275872887	0.999872057938209
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	1/422	229/18639	0.00436681222707424	0.192874438626627	0.994892424511825	0.999872057938209
GO:0000287	magnesium ion binding	1/422	230/18639	0.00434782608695652	0.192035854110859	0.995009502016226	0.999872057938209
GO:0004674	protein serine/threonine kinase activity	3/422	433/18639	0.0069284064665127	0.306015564287512	0.997200695949099	0.999872057938209
GO:0141003	histone H2AX kinase activity	2/422	354/18639	0.00564971751412429	0.249538115511286	0.997391234867121	0.999872057938209
GO:0045182	translation regulator activity	2/422	356/18639	0.00561797752808989	0.248136215985942	0.997497449762836	0.999872057938209
GO:0140996	histone H3 kinase activity	2/422	357/18639	0.00560224089635854	0.24744115655741	0.997548952187803	0.999872057938209
GO:0035173	histone kinase activity	2/422	360/18639	0.00555555555555556	0.245379146919431	0.99769729051836	0.999872057938209
GO:0106310	protein serine kinase activity	2/422	361/18639	0.00554016620498615	0.244699426290846	0.997744747744548	0.999872057938209
GO:0005096	GTPase activator activity	1/422	271/18639	0.003690036900369	0.162982459208478	0.998073542801465	0.999872057938209
GO:0004842	ubiquitin-protein transferase activity	2/422	449/18639	0.0044543429844098	0.196740518688185	0.99964843979955	0.999872057938209
GO:0019787	ubiquitin-like protein transferase activity	2/422	479/18639	0.00417536534446764	0.184418565534437	0.9998153481929	0.999872057938209
GO:0016755	aminoacyltransferase activity	2/422	496/18639	0.00403225806451613	0.178097767925394	0.999872057938209	0.999872057938209