ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003712 transcription coregulator activity 165/2792 495/18639 0.333333333333333 2.22528653295129 3.31626441341192e-25 4.21165580503314e-22 GO:0140297 DNA-binding transcription factor binding 142/2792 488/18639 0.290983606557377 1.94256570294518 5.35971573997804e-16 3.40341949488605e-13 GO:0003714 transcription corepressor activity 74/2792 204/18639 0.362745098039216 2.42163534468229 3.98107500153403e-14 1.68532175064941e-11 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 102/2792 349/18639 0.292263610315186 1.95111082831832 5.51281238935839e-12 1.75031793362129e-09 GO:0003713 transcription coactivator activity 81/2792 256/18639 0.31640625 2.11228370119986 1.08337679045176e-11 2.75177704774748e-09 GO:0042393 histone binding 72/2792 247/18639 0.291497975708502 1.94599955918007 8.05585181490878e-09 1.70515530082236e-06 GO:0016922 nuclear receptor binding 45/2792 137/18639 0.328467153284672 2.19280059816368 1.17827234549319e-07 2.13772268396621e-05 GO:0001222 transcription corepressor binding 22/2792 49/18639 0.448979591836735 2.99732471785276 5.4193611610411e-07 8.60323584315275e-05 GO:0140517 protein-RNA adaptor activity 13/2792 22/18639 0.590909090909091 3.94482612659547 2.43748027913347e-06 0.000337273315881897 GO:0001221 transcription coregulator binding 37/2792 115/18639 0.321739130434783 2.14788526223994 2.65569540064486e-06 0.000337273315881897 GO:0031625 ubiquitin protein ligase binding 75/2792 302/18639 0.248344370860927 1.65791215203325 4.33070838528172e-06 0.00049999996811889 GO:0043995 histone H4K5 acetyltransferase activity 15/2792 30/18639 0.5 3.33792979942693 6.80661452445684e-06 0.000617457174718585 GO:0043996 histone H4K8 acetyltransferase activity 15/2792 30/18639 0.5 3.33792979942693 6.80661452445684e-06 0.000617457174718585 GO:0043997 histone H4K12 acetyltransferase activity 15/2792 30/18639 0.5 3.33792979942693 6.80661452445684e-06 0.000617457174718585 GO:0044389 ubiquitin-like protein ligase binding 78/2792 322/18639 0.242236024844721 1.61713369164783 7.56493571716574e-06 0.000640497890720033 GO:0002039 p53 binding 25/2792 69/18639 0.36231884057971 2.41878970972966 1.08363478411135e-05 0.000860135109888387 GO:0046966 nuclear thyroid hormone receptor binding 14/2792 28/18639 0.5 3.33792979942693 1.38472835038961e-05 0.00103447353234988 GO:0140030 modification-dependent protein binding 47/2792 173/18639 0.271676300578035 1.81367283899498 2.33540145511217e-05 0.00164775547110692 GO:0019787 ubiquitin-like protein transferase activity 105/2792 479/18639 0.219206680584551 1.46339302271327 2.61902290641237e-05 0.00175061004797037 GO:0045296 cadherin binding 78/2792 334/18639 0.233532934131737 1.55903307997186 3.01860628064848e-05 0.0018805651814157 GO:0106310 protein serine kinase activity 83/2792 361/18639 0.229916897506925 1.53489292716031 3.10959596927005e-05 0.0018805651814157 GO:0004674 protein serine/threonine kinase activity 96/2792 433/18639 0.221709006928406 1.48009820205536 3.60546508245763e-05 0.00208133666123691 GO:0140098 catalytic activity, acting on RNA 87/2792 387/18639 0.224806201550388 1.50077463850203 4.86098253091694e-05 0.0026841077453324 GO:0004402 histone acetyltransferase activity 17/2792 42/18639 0.404761904761905 2.70213364715514 5.44044562623758e-05 0.00287890247721739 GO:0048027 mRNA 5'-UTR binding 12/2792 24/18639 0.5 3.33792979942693 5.76947180322853e-05 0.00293089167604009 GO:0140097 catalytic activity, acting on DNA 77/2792 336/18639 0.229166666666667 1.52988449140401 6.62574536286076e-05 0.00305295088309041 GO:0010485 histone H4 acetyltransferase activity 15/2792 35/18639 0.428571428571429 2.86108268522309 6.77651414111743e-05 0.00305295088309041 GO:0016755 aminoacyltransferase activity 106/2792 496/18639 0.213709677419355 1.42669580136796 7.13343249303279e-05 0.00305295088309041 GO:0036002 pre-mRNA binding 21/2792 59/18639 0.355932203389831 2.37615341654121 7.27543155752272e-05 0.00305295088309041 GO:0036408 histone H3K14 acetyltransferase activity 13/2792 28/18639 0.464285714285714 3.09950624232501 7.57082207105952e-05 0.00305295088309041 GO:0061733 protein-lysine-acetyltransferase activity 18/2792 47/18639 0.382978723404255 2.5567121867951 7.87113111254489e-05 0.00305295088309041 GO:0140938 histone H3 methyltransferase activity 18/2792 47/18639 0.382978723404255 2.5567121867951 7.87113111254489e-05 0.00305295088309041 GO:0042809 nuclear vitamin D receptor binding 9/2792 15/18639 0.6 4.00551575931232 7.93286449936877e-05 0.00305295088309041 GO:0051059 NF-kappaB binding 14/2792 32/18639 0.4375 2.92068857449857 9.00378792780974e-05 0.00336317960832893 GO:0046972 histone H4K16 acetyltransferase activity 11/2792 22/18639 0.5 3.33792979942693 0.000118255475628733 0.00417918525481066 GO:0010484 histone H3 acetyltransferase activity 13/2792 29/18639 0.448275862068966 2.9926267167276 0.000118465093837153 0.00417918525481066 GO:0034212 protein N-acetyltransferase activity 19/2792 53/18639 0.358490566037736 2.39323268638158 0.000142028916043604 0.00487504657771288 GO:0060590 ATPase regulator activity 18/2792 49/18639 0.36734693877551 2.45235658733407 0.00014758633807699 0.00493249077257309 GO:0032452 histone demethylase activity 13/2792 30/18639 0.433333333333333 2.89287249283668 0.000180511551135663 0.00587819666518698 GO:0140463 chromatin-protein adaptor activity 19/2792 54/18639 0.351851851851852 2.34891356255969 0.000188637756696618 0.00598924877511762 GO:0035198 miRNA binding 16/2792 42/18639 0.380952380952381 2.54318460908719 0.000209081013814808 0.00647641189133673 GO:0004518 nuclease activity 51/2792 209/18639 0.244019138755981 1.62903750976817 0.000220292656693329 0.00663197266724053 GO:0140857 histone H3T45 kinase activity 58/2792 246/18639 0.235772357723577 1.57398315745335 0.000228119327286888 0.00663197266724053 GO:0008276 protein methyltransferase activity 28/2792 95/18639 0.294736842105263 1.9676217765043 0.000229769131778412 0.00663197266724053 GO:0140457 protein demethylase activity 13/2792 31/18639 0.419354838709677 2.79955402532582 0.000268479328289676 0.00669345668767914 GO:0004679 AMP-activated protein kinase activity 58/2792 248/18639 0.233870967741935 1.56128974489324 0.000285534853859188 0.00669345668767914 GO:0003735 structural constituent of ribosome 44/2792 175/18639 0.251428571428571 1.67850184199754 0.000287561600832773 0.00669345668767914 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 57/2792 243/18639 0.234567901234568 1.5659423750398 0.000295620105319721 0.00669345668767914 GO:0001098 basal transcription machinery binding 20/2792 60/18639 0.333333333333333 2.22528653295129 0.000297412702989616 0.00669345668767914 GO:0001099 basal RNA polymerase II transcription machinery binding 20/2792 60/18639 0.333333333333333 2.22528653295129 0.000297412702989616 0.00669345668767914 GO:0043998 histone H2A acetyltransferase activity 11/2792 24/18639 0.458333333333333 3.05976898280802 0.000313104643593524 0.00669345668767914 GO:0019789 SUMO transferase activity 12/2792 28/18639 0.428571428571429 2.86108268522309 0.000361948568105693 0.00669345668767914 GO:0141052 histone H3 demethylase activity 12/2792 28/18639 0.428571428571429 2.86108268522309 0.000361948568105693 0.00669345668767914 GO:0004676 3-phosphoinositide-dependent protein kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0004711 ribosomal protein S6 kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0035175 histone H3S10 kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0035979 histone H2AXS139 kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0044022 histone H3S28 kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0044023 histone H4S1 kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0044024 histone H2AS1 kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0044025 histone H2BS14 kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0072354 histone H3T3 kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0072371 histone H2AS121 kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0072518 Rho-dependent protein serine/threonine kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0140823 histone H2BS36 kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0140855 histone H3S57 kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0140995 histone H2A kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0140997 histone H4 kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0140998 histone H2B kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:1990244 histone H2AT120 kinase activity 57/2792 245/18639 0.23265306122449 1.55315917197825 0.000368930683572866 0.00669345668767914 GO:0001046 core promoter sequence-specific DNA binding 16/2792 44/18639 0.363636363636364 2.42758530867413 0.000388934305327536 0.00695699391219677 GO:0004677 DNA-dependent protein kinase activity 57/2792 246/18639 0.231707317073171 1.5468455168076 0.000411397600548 0.00725659656522166 GO:0003727 single-stranded RNA binding 26/2792 89/18639 0.292134831460674 1.9502511187663 0.000440432400356975 0.0076623171021008 GO:0035402 histone H3T11 kinase activity 57/2792 247/18639 0.230769230769231 1.54058298435089 0.000458205155640528 0.00775894063551293 GO:0035403 histone H3T6 kinase activity 57/2792 247/18639 0.230769230769231 1.54058298435089 0.000458205155640528 0.00775894063551293 GO:0042974 nuclear retinoic acid receptor binding 11/2792 25/18639 0.44 2.9373782234957 0.000483803267494002 0.00808460723312346 GO:0098641 cadherin binding involved in cell-cell adhesion 9/2792 18/18639 0.5 3.33792979942693 0.000502388660631303 0.00828615063638642 GO:0061980 regulatory RNA binding 19/2792 58/18639 0.327586206896552 2.18691952376247 0.00053493656171409 0.00853971089015552 GO:0051087 protein-folding chaperone binding 35/2792 134/18639 0.261194029850746 1.74369467134243 0.000544125041578954 0.00853971089015552 GO:0001727 lipid kinase activity 15/2792 41/18639 0.365853658536585 2.44238765811727 0.00054478248227677 0.00853971089015552 GO:0140416 transcription regulator inhibitor activity 13/2792 33/18639 0.393939393939394 2.62988408439698 0.000556741817635593 0.00853971089015552 GO:0019207 kinase regulator activity 64/2792 287/18639 0.222996515679443 1.48869342970957 0.000570547198023761 0.00853971089015552 GO:0004842 ubiquitin-protein transferase activity 93/2792 449/18639 0.207126948775056 1.38275042916127 0.0005832911786451 0.00853971089015552 GO:0032931 histone H3K56 acetyltransferase activity 10/2792 22/18639 0.454545454545455 3.03448163584267 0.000638797271310846 0.00853971089015552 GO:0043992 histone H3K9 acetyltransferase activity 10/2792 22/18639 0.454545454545455 3.03448163584267 0.000638797271310846 0.00853971089015552 GO:0043993 histone H3K18 acetyltransferase activity 10/2792 22/18639 0.454545454545455 3.03448163584267 0.000638797271310846 0.00853971089015552 GO:0043994 histone H3K23 acetyltransferase activity 10/2792 22/18639 0.454545454545455 3.03448163584267 0.000638797271310846 0.00853971089015552 GO:0043999 histone H2AK5 acetyltransferase activity 10/2792 22/18639 0.454545454545455 3.03448163584267 0.000638797271310846 0.00853971089015552 GO:0044012 histone H2AK9 acetyltransferase activity 10/2792 22/18639 0.454545454545455 3.03448163584267 0.000638797271310846 0.00853971089015552 GO:0044014 histone H2BK5 acetyltransferase activity 10/2792 22/18639 0.454545454545455 3.03448163584267 0.000638797271310846 0.00853971089015552 GO:0044015 histone H2BK12 acetyltransferase activity 10/2792 22/18639 0.454545454545455 3.03448163584267 0.000638797271310846 0.00853971089015552 GO:0044016 histone H3K4 acetyltransferase activity 10/2792 22/18639 0.454545454545455 3.03448163584267 0.000638797271310846 0.00853971089015552 GO:0044017 histone H3K27 acetyltransferase activity 10/2792 22/18639 0.454545454545455 3.03448163584267 0.000638797271310846 0.00853971089015552 GO:0044018 histone H3K36 acetyltransferase activity 10/2792 22/18639 0.454545454545455 3.03448163584267 0.000638797271310846 0.00853971089015552 GO:0140908 histone H3K122 acetyltransferase activity 10/2792 22/18639 0.454545454545455 3.03448163584267 0.000638797271310846 0.00853971089015552 GO:1990247 N6-methyladenosine-containing RNA reader activity 7/2792 12/18639 0.583333333333333 3.89425143266476 0.000663114802477417 0.00872208045306767 GO:0016407 acetyltransferase activity 27/2792 96/18639 0.28125 1.87758551217765 0.000666653014553121 0.00872208045306767 GO:0070063 RNA polymerase binding 19/2792 59/18639 0.322033898305085 2.14985309115633 0.000679608206483634 0.00872208045306767 GO:1990841 promoter-specific chromatin binding 21/2792 68/18639 0.308823529411765 2.06166252317546 0.00067991020854622 0.00872208045306767 GO:0052742 phosphatidylinositol kinase activity 11/2792 26/18639 0.423076923076923 2.82440213797664 0.000725795971213092 0.00921760883440627 GO:0008080 N-acetyltransferase activity 21/2792 69/18639 0.304347826086957 2.03178335617292 0.000841341102358198 0.01057923960391 GO:0044013 histone H2B acetyltransferase activity 10/2792 23/18639 0.434782608695652 2.9025476516756 0.000979378433054096 0.0120283390512432 GO:0019902 phosphatase binding 45/2792 190/18639 0.236842105263158 1.58112464183381 0.000979898725259806 0.0120283390512432 GO:0141003 histone H2AX kinase activity 75/2792 354/18639 0.211864406779661 1.41437703365548 0.000984997843566372 0.0120283390512432 GO:0016278 lysine N-methyltransferase activity 21/2792 70/18639 0.3 2.00275787965616 0.00103474149766569 0.0125154447812898 GO:0001671 ATPase activator activity 11/2792 27/18639 0.407407407407407 2.71979465138491 0.00106027973463548 0.0127033515376138 GO:0061659 ubiquitin-like protein ligase activity 78/2792 372/18639 0.209677419354839 1.39977701266291 0.00107924338433402 0.0128097111972356 GO:0140996 histone H3 kinase activity 75/2792 357/18639 0.210084033613445 1.40249151236426 0.00125776539728965 0.0147903893940543 GO:0032182 ubiquitin-like protein binding 31/2792 120/18639 0.258333333333333 1.72459706303725 0.00132964683619045 0.0148501993674199 GO:0140034 methylation-dependent protein binding 22/2792 76/18639 0.289473684210526 1.93248567335244 0.001340988064772 0.0148501993674199 GO:0140296 general transcription initiation factor binding 17/2792 53/18639 0.320754716981132 2.14131345623615 0.00134400742901774 0.0148501993674199 GO:0043021 ribonucleoprotein complex binding 42/2792 177/18639 0.23728813559322 1.58410227769414 0.00136250418572693 0.0148501993674199 GO:0004532 RNA exonuclease activity 14/2792 40/18639 0.35 2.33655085959885 0.00136701499432117 0.0148501993674199 GO:0061791 GTPase motor activity 14/2792 40/18639 0.35 2.33655085959885 0.00136701499432117 0.0148501993674199 GO:1990606 membrane scission GTPase motor activity 14/2792 40/18639 0.35 2.33655085959885 0.00136701499432117 0.0148501993674199 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 6/2792 10/18639 0.6 4.00551575931232 0.00136808923306152 0.0148501993674199 GO:0045322 unmethylated CpG binding 6/2792 10/18639 0.6 4.00551575931232 0.00136808923306152 0.0148501993674199 GO:0042054 histone methyltransferase activity 20/2792 67/18639 0.298507462686567 1.99279391010563 0.00144332582580679 0.0154725942556206 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 40/2792 167/18639 0.239520958083832 1.59900828715063 0.00144979426489673 0.0154725942556206 GO:0031072 heat shock protein binding 33/2792 131/18639 0.251908396946565 1.68170508978762 0.00150036269917247 0.015878838566242 GO:0004540 RNA nuclease activity 31/2792 121/18639 0.256198347107438 1.71034419474769 0.00153582367464409 0.0161198022049421 GO:0035173 histone kinase activity 75/2792 360/18639 0.208333333333333 1.39080408309456 0.00159565308568069 0.016516663969738 GO:0051020 GTPase binding 67/2792 315/18639 0.212698412698413 1.41994474007368 0.00159964540809274 0.016516663969738 GO:1990226 histone methyltransferase binding 8/2792 17/18639 0.470588235294118 3.14158098769594 0.00171283398400957 0.0175427351588077 GO:0019783 ubiquitin-like protein peptidase activity 32/2792 127/18639 0.251968503937008 1.68210635561672 0.00174592908670646 0.0177103727417389 GO:0019887 protein kinase regulator activity 56/2792 255/18639 0.219607843137255 1.46607112759144 0.00175709209878669 0.0177103727417389 GO:0061650 ubiquitin-like protein conjugating enzyme activity 14/2792 41/18639 0.341463414634146 2.27956181424278 0.0017933577783442 0.017933577783442 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 32/2792 128/18639 0.25 1.66896489971347 0.00199992559132563 0.019843011726434 GO:0016279 protein-lysine N-methyltransferase activity 20/2792 69/18639 0.289855072463768 1.93503176778373 0.00213695630468869 0.0210382519918964 GO:0061665 SUMO ligase activity 7/2792 14/18639 0.5 3.33792979942693 0.00217993648708069 0.0212963026045575 GO:0031491 nucleosome binding 21/2792 74/18639 0.283783783783784 1.89450069697204 0.00223591845049326 0.0215122456979276 GO:0035064 methylated histone binding 21/2792 74/18639 0.283783783783784 1.89450069697204 0.00223591845049326 0.0215122456979276 GO:0016741 transferase activity, transferring one-carbon groups 48/2792 215/18639 0.223255813953488 1.49042446858133 0.00253476674490465 0.0240567012895472 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 13/2792 38/18639 0.342105263157895 2.28384670487106 0.00253826612031443 0.0240567012895472 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 6/2792 11/18639 0.545454545454545 3.6413779630112 0.00262890758614381 0.0245493576059017 GO:0140537 transcription regulator activator activity 6/2792 11/18639 0.545454545454545 3.6413779630112 0.00262890758614381 0.0245493576059017 GO:0003725 double-stranded RNA binding 21/2792 75/18639 0.28 1.86924068767908 0.00267496908064879 0.0247971586308319 GO:0015631 tubulin binding 78/2792 385/18639 0.202597402597403 1.35251181483273 0.00287570410443937 0.0263644808731188 GO:0035925 mRNA 3'-UTR AU-rich region binding 11/2792 30/18639 0.366666666666667 2.44781518624642 0.00288616828506098 0.0263644808731188 GO:0070034 telomerase RNA binding 9/2792 22/18639 0.409090909090909 2.7310334722584 0.00291712982185848 0.0263644808731188 GO:0031267 small GTPase binding 60/2792 283/18639 0.212014134275618 1.41537659339658 0.00292708015992893 0.0263644808731188 GO:0060589 nucleoside-triphosphatase regulator activity 96/2792 490/18639 0.195918367346939 1.30792351324484 0.00299956865934433 0.0268271281504739 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 15/2792 48/18639 0.3125 2.08620612464183 0.00335691117802304 0.0298131272453794 GO:0016887 ATP hydrolysis activity 83/2792 417/18639 0.199040767386091 1.32876821751768 0.00357040394917281 0.0311051377243708 GO:0000175 3'-5'-RNA exonuclease activity 12/2792 35/18639 0.342857142857143 2.28886614817847 0.00360035846100985 0.0311051377243708 GO:0043015 gamma-tubulin binding 12/2792 35/18639 0.342857142857143 2.28886614817847 0.00360035846100985 0.0311051377243708 GO:0140566 histone reader activity 12/2792 35/18639 0.342857142857143 2.28886614817847 0.00360035846100985 0.0311051377243708 GO:0031490 chromatin DNA binding 31/2792 128/18639 0.2421875 1.61680974659742 0.00391201281829344 0.0335692991840045 GO:0008234 cysteine-type peptidase activity 42/2792 187/18639 0.224598930481283 1.49939092594579 0.00403829289874792 0.0342332602689425 GO:0030695 GTPase regulator activity 95/2792 489/18639 0.194274028629857 1.29694613883664 0.00404329845696171 0.0342332602689425 GO:0023026 MHC class II protein complex binding 10/2792 27/18639 0.37037037037037 2.4725405921681 0.00408330033737528 0.0343429895924941 GO:0008017 microtubule binding 58/2792 276/18639 0.210144927536232 1.4028980316432 0.00415356232248771 0.0347041062471013 GO:0032451 demethylase activity 13/2792 40/18639 0.325 2.16965436962751 0.0042203973045206 0.0350320560571318 GO:0008168 methyltransferase activity 45/2792 204/18639 0.220588235294118 1.47261608798247 0.00428643595940108 0.0353491796651908 GO:0008170 N-methyltransferase activity 25/2792 98/18639 0.255102040816327 1.70302540787088 0.00442479905702013 0.0362548051768746 GO:0000993 RNA polymerase II complex binding 12/2792 36/18639 0.333333333333333 2.22528653295129 0.00467611053532571 0.0380683357683568 GO:0016410 N-acyltransferase activity 24/2792 94/18639 0.25531914893617 1.70447479119673 0.00516297335416655 0.041607656435234 GO:0003684 damaged DNA binding 20/2792 74/18639 0.27027027027027 1.80428637806861 0.00517638560375352 0.041607656435234 GO:0016779 nucleotidyltransferase activity 32/2792 136/18639 0.235294117647059 1.57079049384797 0.00543587208574739 0.0433397982914008 GO:0101005 deubiquitinase activity 28/2792 115/18639 0.243478260869565 1.62542668493833 0.00546013206820798 0.0433397982914008 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 49/2792 229/18639 0.213973799126638 1.42845904080279 0.00556053289387645 0.043862588665982 GO:0035035 histone acetyltransferase binding 9/2792 24/18639 0.375 2.5034473495702 0.00578735045957108 0.0450916262800937 GO:0140033 acetylation-dependent protein binding 9/2792 24/18639 0.375 2.5034473495702 0.00578735045957108 0.0450916262800937 GO:0043130 ubiquitin binding 25/2792 100/18639 0.25 1.66896489971347 0.00584870614540595 0.0452918097845461 GO:0019209 kinase activator activity 34/2792 148/18639 0.22972972972973 1.53364342135832 0.00630208114042627 0.0485069275657053 GO:0004519 endonuclease activity 30/2792 127/18639 0.236220472440945 1.57697470839068 0.00655269605441943 0.0501320722235703 GO:0004520 DNA endonuclease activity 13/2792 42/18639 0.30952380952381 2.06633749488334 0.00670230421759215 0.0506662283115597 GO:0043175 RNA polymerase core enzyme binding 13/2792 42/18639 0.30952380952381 2.06633749488334 0.00670230421759215 0.0506662283115597 GO:0008094 ATP-dependent activity, acting on DNA 45/2792 210/18639 0.214285714285714 1.43054134261154 0.00742810587202732 0.0544537875218699 GO:0019888 protein phosphatase regulator activity 26/2792 107/18639 0.242990654205607 1.62217149131029 0.00743312537248808 0.0544537875218699 GO:0004535 poly(A)-specific ribonuclease activity 6/2792 13/18639 0.461538461538462 3.08116596870179 0.00746059766047667 0.0544537875218699 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 6/2792 13/18639 0.461538461538462 3.08116596870179 0.00746059766047667 0.0544537875218699 GO:0046974 histone H3K9 methyltransferase activity 6/2792 13/18639 0.461538461538462 3.08116596870179 0.00746059766047667 0.0544537875218699 GO:0097157 pre-mRNA intronic binding 6/2792 13/18639 0.461538461538462 3.08116596870179 0.00746059766047667 0.0544537875218699 GO:0030295 protein kinase activator activity 32/2792 139/18639 0.23021582733813 1.53688854074334 0.00762228518640645 0.0553160124956354 GO:0016504 peptidase activator activity 16/2792 57/18639 0.280701754385965 1.87392550143266 0.00797167578953571 0.0575228877994906 GO:0035591 signaling adaptor activity 30/2792 129/18639 0.232558139534884 1.55252548810555 0.00825028876552509 0.0591969871876659 GO:0030145 manganese ion binding 18/2792 68/18639 0.264705882352941 1.76713930557897 0.0097192313781272 0.0676117089358642 GO:0005131 growth hormone receptor binding 5/2792 10/18639 0.5 3.33792979942693 0.00979571216078663 0.0676117089358642 GO:0016303 1-phosphatidylinositol-3-kinase activity 5/2792 10/18639 0.5 3.33792979942693 0.00979571216078663 0.0676117089358642 GO:0031996 thioesterase binding 5/2792 10/18639 0.5 3.33792979942693 0.00979571216078663 0.0676117089358642 GO:0042975 peroxisome proliferator activated receptor binding 5/2792 10/18639 0.5 3.33792979942693 0.00979571216078663 0.0676117089358642 GO:0051864 histone H3K36 demethylase activity 5/2792 10/18639 0.5 3.33792979942693 0.00979571216078663 0.0676117089358642 GO:0140999 histone H3K4 trimethyltransferase activity 5/2792 10/18639 0.5 3.33792979942693 0.00979571216078663 0.0676117089358642 GO:0050681 nuclear androgen receptor binding 9/2792 26/18639 0.346153846153846 2.31087447652634 0.0104519161584811 0.0717509920068703 GO:0005154 epidermal growth factor receptor binding 11/2792 35/18639 0.314285714285714 2.09812730249693 0.0107967955665734 0.0733258308531988 GO:0061631 ubiquitin conjugating enzyme activity 11/2792 35/18639 0.314285714285714 2.09812730249693 0.0107967955665734 0.0733258308531988 GO:0061630 ubiquitin protein ligase activity 69/2792 353/18639 0.195467422096317 1.30491306606492 0.0111433293695765 0.0745838044193729 GO:0003697 single-stranded DNA binding 28/2792 121/18639 0.231404958677686 1.54482701461081 0.0111773173652628 0.0745838044193729 GO:0004407 histone deacetylase activity 8/2792 22/18639 0.363636363636364 2.42758530867413 0.0112472832097982 0.0745838044193729 GO:0033558 protein lysine deacetylase activity 8/2792 22/18639 0.363636363636364 2.42758530867413 0.0112472832097982 0.0745838044193729 GO:0140104 molecular carrier activity 51/2792 249/18639 0.204819277108434 1.36734473711465 0.0112756617704879 0.0745838044193729 GO:0042826 histone deacetylase binding 29/2792 127/18639 0.228346456692913 1.52440888477765 0.0119687620061538 0.0787581748591468 GO:0140597 protein carrier chaperone 40/2792 188/18639 0.212765957446809 1.42039565933061 0.0124741754271874 0.0816608391367424 GO:0019903 protein phosphatase binding 32/2792 144/18639 0.222222222222222 1.48352435530086 0.012856690454017 0.0837333173159058 GO:0019208 phosphatase regulator activity 27/2792 117/18639 0.230769230769231 1.54058298435089 0.013016445644569 0.0839596649144257 GO:0019003 GDP binding 19/2792 75/18639 0.253333333333333 1.69121776504298 0.013023664557592 0.0839596649144257 GO:0019843 rRNA binding 17/2792 65/18639 0.261538461538462 1.74599404893101 0.013295224112587 0.0848549737533693 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 16/2792 60/18639 0.266666666666667 1.78022922636103 0.0132961730526933 0.0848549737533693 GO:0140767 enzyme-substrate adaptor activity 31/2792 139/18639 0.223021582733813 1.48886077384511 0.0134769850257335 0.0852346724627335 GO:0055106 ubiquitin-protein transferase regulator activity 11/2792 36/18639 0.305555555555556 2.03984598853868 0.0134898969803224 0.0852346724627335 GO:0070577 lysine-acetylated histone binding 8/2792 23/18639 0.347826086956522 2.32203812134048 0.0150256597786332 0.0940245127982969 GO:0000287 magnesium ion binding 47/2792 230/18639 0.204347826086957 1.36419739628753 0.0151031500872855 0.0940245127982969 GO:0005085 guanyl-nucleotide exchange factor activity 47/2792 230/18639 0.204347826086957 1.36419739628753 0.0151031500872855 0.0940245127982969 GO:0030515 snoRNA binding 10/2792 32/18639 0.3125 2.08620612464183 0.0154077472211651 0.0954528730286813 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 5/2792 11/18639 0.454545454545455 3.03448163584267 0.0157680493063223 0.0967411720726054 GO:1990948 ubiquitin ligase inhibitor activity 5/2792 11/18639 0.454545454545455 3.03448163584267 0.0157680493063223 0.0967411720726054 GO:0042800 histone H3K4 methyltransferase activity 7/2792 19/18639 0.368421052631579 2.45952722063037 0.0161621256516529 0.0986822095076884 GO:0004722 protein serine/threonine phosphatase activity 24/2792 103/18639 0.233009708737864 1.55554010070381 0.0164538708638566 0.0993361370336599 GO:0031386 protein tag activity 6/2792 15/18639 0.4 2.67034383954155 0.0166603127465902 0.0993361370336599 GO:0141047 molecular tag activity 6/2792 15/18639 0.4 2.67034383954155 0.0166603127465902 0.0993361370336599 GO:0141050 histone H3K deacetylase activity 6/2792 15/18639 0.4 2.67034383954155 0.0166603127465902 0.0993361370336599 GO:0141051 histone H4K deacetylase activity 6/2792 15/18639 0.4 2.67034383954155 0.0166603127465902 0.0993361370336599 GO:0005525 GTP binding 72/2792 378/18639 0.19047619047619 1.27159230454359 0.0172920595838602 0.102621101268703 GO:0004197 cysteine-type endopeptidase activity 21/2792 88/18639 0.238636363636364 1.5931028588174 0.018399303443254 0.108684257548524 GO:0017124 SH3 domain binding 26/2792 115/18639 0.226086956521739 1.50932477887131 0.0188383072485289 0.110762269470517 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 20/2792 83/18639 0.240963855421687 1.6086408671937 0.0190230990110418 0.111333344442503 GO:0070300 phosphatidic acid binding 8/2792 24/18639 0.333333333333333 2.22528653295129 0.0196448144381643 0.114444561176462 GO:0051082 unfolded protein binding 27/2792 121/18639 0.223140495867769 1.48965462123186 0.0199504264732036 0.115694253977025 GO:0043539 protein serine/threonine kinase activator activity 18/2792 73/18639 0.246575342465753 1.64610236684068 0.0201673700363609 0.116420727028084 GO:1901505 carbohydrate derivative transmembrane transporter activity 14/2792 53/18639 0.264150943396226 1.763434611018 0.0214691106234597 0.123374527112189 GO:0052745 inositol phosphate phosphatase activity 7/2792 20/18639 0.35 2.33655085959885 0.0217182329947757 0.124243945510654 GO:0031435 mitogen-activated protein kinase kinase kinase binding 6/2792 16/18639 0.375 2.5034473495702 0.0233435242306173 0.129447409000648 GO:0000340 RNA 7-methylguanosine cap binding 5/2792 12/18639 0.416666666666667 2.78160816618911 0.0237490128324024 0.129447409000648 GO:0035197 siRNA binding 5/2792 12/18639 0.416666666666667 2.78160816618911 0.0237490128324024 0.129447409000648 GO:0035259 nuclear glucocorticoid receptor binding 5/2792 12/18639 0.416666666666667 2.78160816618911 0.0237490128324024 0.129447409000648 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 5/2792 12/18639 0.416666666666667 2.78160816618911 0.0237490128324024 0.129447409000648 GO:0070679 inositol 1,4,5 trisphosphate binding 5/2792 12/18639 0.416666666666667 2.78160816618911 0.0237490128324024 0.129447409000648 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 5/2792 12/18639 0.416666666666667 2.78160816618911 0.0237490128324024 0.129447409000648 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 5/2792 12/18639 0.416666666666667 2.78160816618911 0.0237490128324024 0.129447409000648 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 5/2792 12/18639 0.416666666666667 2.78160816618911 0.0237490128324024 0.129447409000648 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 5/2792 12/18639 0.416666666666667 2.78160816618911 0.0237490128324024 0.129447409000648 GO:1990817 poly(A) RNA polymerase activity 5/2792 12/18639 0.416666666666667 2.78160816618911 0.0237490128324024 0.129447409000648 GO:0000217 DNA secondary structure binding 11/2792 39/18639 0.282051282051282 1.88293475865109 0.02462417513637 0.13364402744953 GO:0003924 GTPase activity 63/2792 331/18639 0.190332326283988 1.27063188739515 0.0249484293255447 0.134827681886986 GO:0017056 structural constituent of nuclear pore 8/2792 25/18639 0.32 2.13627507163324 0.0251906901486471 0.135265930482485 GO:0016763 pentosyltransferase activity 13/2792 49/18639 0.26530612244898 1.77114642418572 0.0252425397829519 0.135265930482485 GO:0140658 ATP-dependent chromatin remodeler activity 33/2792 158/18639 0.208860759493671 1.39432510608973 0.0277606865401747 0.148121699516847 GO:0160215 deacylase activity 16/2792 65/18639 0.246153846153846 1.64328851664095 0.0278748710114381 0.148121699516847 GO:0004843 cysteine-type deubiquitinase activity 24/2792 108/18639 0.222222222222222 1.48352435530086 0.0283080615515166 0.148828243728098 GO:0005123 death receptor binding 7/2792 21/18639 0.333333333333333 2.22528653295129 0.0284682812305262 0.148828243728098 GO:0009931 calcium-dependent protein serine/threonine kinase activity 7/2792 21/18639 0.333333333333333 2.22528653295129 0.0284682812305262 0.148828243728098 GO:0140713 histone chaperone activity 34/2792 164/18639 0.207317073170732 1.38401967293312 0.0285229869285523 0.148828243728098 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 15/2792 60/18639 0.25 1.66896489971347 0.0285937728107527 0.148828243728098 GO:0030331 nuclear estrogen receptor binding 11/2792 40/18639 0.275 1.83586138968481 0.0295039630592848 0.151966311223612 GO:0032813 tumor necrosis factor receptor superfamily binding 13/2792 50/18639 0.26 1.73572349570201 0.0295775810047114 0.151966311223612 GO:0019001 guanyl nucleotide binding 74/2792 400/18639 0.185 1.23503402578797 0.0296753111680754 0.151966311223612 GO:0032561 guanyl ribonucleotide binding 74/2792 400/18639 0.185 1.23503402578797 0.0296753111680754 0.151966311223612 GO:0051787 misfolded protein binding 6/2792 17/18639 0.352941176470588 2.35618574077195 0.0316102927151433 0.161225187743904 GO:0034237 protein kinase A regulatory subunit binding 8/2792 26/18639 0.307692307692308 2.05411064580119 0.0317412563664988 0.161245582341814 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 19/2792 82/18639 0.231707317073171 1.5468455168076 0.0320863127761505 0.162349072612395 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 15/2792 61/18639 0.245901639344262 1.6416048193903 0.0328365130605588 0.165485601535356 GO:0003724 RNA helicase activity 18/2792 77/18639 0.233766233766234 1.56059055557623 0.0334701867763205 0.167666053851623 GO:0035325 Toll-like receptor binding 5/2792 13/18639 0.384615384615385 2.56763830725149 0.0339292723148559 0.167666053851623 GO:0043560 insulin receptor substrate binding 5/2792 13/18639 0.384615384615385 2.56763830725149 0.0339292723148559 0.167666053851623 GO:0046975 histone H3K36 methyltransferase activity 5/2792 13/18639 0.384615384615385 2.56763830725149 0.0339292723148559 0.167666053851623 GO:0051011 microtubule minus-end binding 5/2792 13/18639 0.384615384615385 2.56763830725149 0.0339292723148559 0.167666053851623 GO:0030544 Hsp70 protein binding 13/2792 51/18639 0.254901960784314 1.70168970166863 0.0344288514020332 0.169475353800706 GO:0004386 helicase activity 32/2792 155/18639 0.206451612903226 1.37824198169886 0.0345884288561273 0.169603492846647 GO:0008137 NADH dehydrogenase (ubiquinone) activity 11/2792 41/18639 0.268292682926829 1.79108428261933 0.0350374853178053 0.171144639821587 GO:0008135 translation factor activity, RNA binding 19/2792 83/18639 0.228915662650602 1.52820882383402 0.0359644543626672 0.174763479951642 GO:0001217 DNA-binding transcription repressor activity 53/2792 278/18639 0.190647482014388 1.27273582280308 0.0360535683049844 0.174763479951642 GO:0061133 endopeptidase activator activity 7/2792 22/18639 0.318181818181818 2.12413714508987 0.0365047469735327 0.176277675499568 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 8/2792 27/18639 0.296296296296296 1.97803247373448 0.0393644278601681 0.189366755236415 GO:0004527 exonuclease activity 19/2792 84/18639 0.226190476190476 1.51001586164552 0.0401765050522882 0.191101728151333 GO:0004860 protein kinase inhibitor activity 19/2792 84/18639 0.226190476190476 1.51001586164552 0.0401765050522882 0.191101728151333 GO:0180051 translation factor activity 19/2792 84/18639 0.226190476190476 1.51001586164552 0.0401765050522882 0.191101728151333 GO:0043495 protein-membrane adaptor activity 12/2792 47/18639 0.25531914893617 1.70447479119673 0.0406973893306697 0.19197528135933 GO:0005548 phospholipid transporter activity 16/2792 68/18639 0.235294117647059 1.57079049384797 0.0409973640703754 0.19197528135933 GO:0023023 MHC protein complex binding 10/2792 37/18639 0.27027027027027 1.80428637806861 0.0413771841705948 0.19197528135933 GO:0000400 four-way junction DNA binding 6/2792 18/18639 0.333333333333333 2.22528653295129 0.0415694506880438 0.19197528135933 GO:0000900 mRNA regulatory element binding translation repressor activity 6/2792 18/18639 0.333333333333333 2.22528653295129 0.0415694506880438 0.19197528135933 GO:0003746 translation elongation factor activity 6/2792 18/18639 0.333333333333333 2.22528653295129 0.0415694506880438 0.19197528135933 GO:0035615 clathrin adaptor activity 6/2792 18/18639 0.333333333333333 2.22528653295129 0.0415694506880438 0.19197528135933 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 6/2792 18/18639 0.333333333333333 2.22528653295129 0.0415694506880438 0.19197528135933 GO:0043022 ribosome binding 24/2792 112/18639 0.214285714285714 1.43054134261154 0.0417664537289036 0.192186218245317 GO:0008186 ATP-dependent activity, acting on RNA 18/2792 79/18639 0.227848101265823 1.52108193391607 0.042145891312749 0.193232064863506 GO:0019210 kinase inhibitor activity 20/2792 90/18639 0.222222222222222 1.48352435530086 0.0425159434026419 0.194227511227896 GO:0140674 ATP-dependent histone chaperone activity 31/2792 152/18639 0.203947368421053 1.36152399713467 0.0429185980705192 0.195364227776199 GO:0008408 3'-5' exonuclease activity 14/2792 58/18639 0.241379310344828 1.61141438593024 0.0442784745870701 0.200119796176438 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 14/2792 58/18639 0.241379310344828 1.61141438593024 0.0442784745870701 0.200119796176438 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 7/2792 23/18639 0.304347826086957 2.03178335617292 0.0459018476213012 0.206721086805151 GO:0061775 cohesin loader activity 31/2792 153/18639 0.202614379084967 1.3526251474802 0.0463705002711052 0.207644177533574 GO:0070742 C2H2 zinc finger domain binding 5/2792 14/18639 0.357142857142857 2.38423557101924 0.0464338160783739 0.207644177533574 GO:0016866 intramolecular transferase activity 8/2792 28/18639 0.285714285714286 1.90738845681539 0.0481163300653276 0.214413119940232 GO:0004536 DNA nuclease activity 15/2792 64/18639 0.234375 1.56465459348138 0.0482913037270349 0.214440404662008 GO:0042162 telomeric DNA binding 10/2792 38/18639 0.263157894736842 1.75680515759312 0.0488841394271427 0.215431781035424 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 4/2792 10/18639 0.4 2.67034383954155 0.0497019778294324 0.215431781035424 GO:0016868 intramolecular phosphotransferase activity 4/2792 10/18639 0.4 2.67034383954155 0.0497019778294324 0.215431781035424 GO:0030957 Tat protein binding 4/2792 10/18639 0.4 2.67034383954155 0.0497019778294324 0.215431781035424 GO:0031434 mitogen-activated protein kinase kinase binding 4/2792 10/18639 0.4 2.67034383954155 0.0497019778294324 0.215431781035424 GO:0032395 MHC class II receptor activity 4/2792 10/18639 0.4 2.67034383954155 0.0497019778294324 0.215431781035424 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 4/2792 10/18639 0.4 2.67034383954155 0.0497019778294324 0.215431781035424 GO:0033192 calmodulin-dependent protein phosphatase activity 18/2792 81/18639 0.222222222222222 1.48352435530086 0.052334730570932 0.219413430795705 GO:0140791 histone H2AXS140 phosphatase activity 18/2792 81/18639 0.222222222222222 1.48352435530086 0.052334730570932 0.219413430795705 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 18/2792 81/18639 0.222222222222222 1.48352435530086 0.052334730570932 0.219413430795705 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 18/2792 81/18639 0.222222222222222 1.48352435530086 0.052334730570932 0.219413430795705 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 18/2792 81/18639 0.222222222222222 1.48352435530086 0.052334730570932 0.219413430795705 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 18/2792 81/18639 0.222222222222222 1.48352435530086 0.052334730570932 0.219413430795705 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 18/2792 81/18639 0.222222222222222 1.48352435530086 0.052334730570932 0.219413430795705 GO:1990439 MAP kinase serine/threonine phosphatase activity 18/2792 81/18639 0.222222222222222 1.48352435530086 0.052334730570932 0.219413430795705 GO:0003925 G protein activity 13/2792 54/18639 0.240740740740741 1.60715138490926 0.0523482437252746 0.219413430795705 GO:0017069 snRNA binding 13/2792 54/18639 0.240740740740741 1.60715138490926 0.0523482437252746 0.219413430795705 GO:0140036 ubiquitin-modified protein reader activity 6/2792 19/18639 0.315789473684211 2.10816618911175 0.0532959083971474 0.22179374441793 GO:0003779 actin binding 79/2792 443/18639 0.178329571106095 1.19050317902812 0.0533407915922813 0.22179374441793 GO:0016791 phosphatase activity 51/2792 273/18639 0.186813186813187 1.24713860637929 0.0534400675526666 0.22179374441793 GO:0098631 cell adhesion mediator activity 17/2792 76/18639 0.223684210526316 1.49328438395415 0.0551314109738686 0.228068051911443 GO:0003954 NADH dehydrogenase activity 11/2792 44/18639 0.25 1.66896489971347 0.0559083403856378 0.230531143797922 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 50/2792 268/18639 0.186567164179104 1.24549619381602 0.0564340617951447 0.231945820323087 GO:0001091 RNA polymerase II general transcription initiation factor binding 7/2792 24/18639 0.291666666666667 1.94712571633238 0.0567135671672987 0.232342678395062 GO:0033549 MAP kinase phosphatase activity 18/2792 82/18639 0.219512195121951 1.46543259487036 0.0580295980757143 0.234829025284328 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 8/2792 29/18639 0.275862068965517 1.84161644106314 0.0580399491580548 0.234829025284328 GO:0097472 cyclin-dependent protein kinase activity 8/2792 29/18639 0.275862068965517 1.84161644106314 0.0580399491580548 0.234829025284328 GO:0052866 phosphatidylinositol phosphate phosphatase activity 9/2792 34/18639 0.264705882352941 1.76713930557897 0.0580600897159678 0.234829025284328 GO:0098632 cell-cell adhesion mediator activity 13/2792 55/18639 0.236363636363636 1.57793045063819 0.0595196310959221 0.239654835841078 GO:0140101 catalytic activity, acting on a tRNA 28/2792 139/18639 0.201438848920863 1.34477747315042 0.0596306520675438 0.239654835841078 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 25/2792 122/18639 0.204918032786885 1.36800401615858 0.0608451026779341 0.242416965086557 GO:0055105 ubiquitin-protein transferase inhibitor activity 5/2792 15/18639 0.333333333333333 2.22528653295129 0.0613205677442659 0.242416965086557 GO:0000510 H3-H4 histone complex chaperone activity 30/2792 151/18639 0.198675496688742 1.3263297216266 0.061463199021946 0.242416965086557 GO:0140584 chromatin extrusion motor activity 30/2792 151/18639 0.198675496688742 1.3263297216266 0.061463199021946 0.242416965086557 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 30/2792 151/18639 0.198675496688742 1.3263297216266 0.061463199021946 0.242416965086557 GO:0140849 ATP-dependent H2AZ histone chaperone activity 30/2792 151/18639 0.198675496688742 1.3263297216266 0.061463199021946 0.242416965086557 GO:0015605 organophosphate ester transmembrane transporter activity 12/2792 50/18639 0.24 1.60220630372493 0.0620165253988892 0.243842065809874 GO:0004715 non-membrane spanning protein tyrosine kinase activity 11/2792 45/18639 0.244444444444444 1.63187679083095 0.0643817511144392 0.251584073585655 GO:0042605 peptide antigen binding 11/2792 45/18639 0.244444444444444 1.63187679083095 0.0643817511144392 0.251584073585655 GO:0015616 DNA translocase activity 30/2792 152/18639 0.197368421052632 1.31760386819484 0.0660233467968869 0.25669519780961 GO:0005096 GTPase activator activity 50/2792 271/18639 0.18450184501845 1.23170841307267 0.0662520122325444 0.25669519780961 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 10/2792 40/18639 0.25 1.66896489971347 0.0664982047868989 0.25669519780961 GO:0140662 ATP-dependent protein folding chaperone 10/2792 40/18639 0.25 1.66896489971347 0.0664982047868989 0.25669519780961 GO:0000339 RNA cap binding 6/2792 20/18639 0.3 2.00275787965616 0.0668291978553066 0.257191155382543 GO:0017025 TBP-class protein binding 7/2792 25/18639 0.28 1.86924068767908 0.0689724637856632 0.259877263520609 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 4/2792 11/18639 0.363636363636364 2.42758530867413 0.0690927941283523 0.259877263520609 GO:0004143 ATP-dependent diacylglycerol kinase activity 4/2792 11/18639 0.363636363636364 2.42758530867413 0.0690927941283523 0.259877263520609 GO:0019206 nucleoside kinase activity 4/2792 11/18639 0.363636363636364 2.42758530867413 0.0690927941283523 0.259877263520609 GO:0050786 RAGE receptor binding 4/2792 11/18639 0.363636363636364 2.42758530867413 0.0690927941283523 0.259877263520609 GO:0070990 snRNP binding 4/2792 11/18639 0.363636363636364 2.42758530867413 0.0690927941283523 0.259877263520609 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 4/2792 11/18639 0.363636363636364 2.42758530867413 0.0690927941283523 0.259877263520609 GO:0051721 protein phosphatase 2A binding 8/2792 30/18639 0.266666666666667 1.78022922636103 0.0691641850944612 0.259877263520609 GO:0005048 signal sequence binding 12/2792 51/18639 0.235294117647059 1.57079049384797 0.0705050404748449 0.26399351548263 GO:0017018 myosin phosphatase activity 18/2792 84/18639 0.214285714285714 1.43054134261154 0.0706754293418065 0.26399351548263 GO:0004521 RNA endonuclease activity 16/2792 73/18639 0.219178082191781 1.46320210385838 0.0717849634121644 0.267351623265246 GO:0003689 DNA clamp loader activity 31/2792 160/18639 0.19375 1.29344779727794 0.0764392863684528 0.2838534903156 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 5/2792 16/18639 0.3125 2.08620612464183 0.0785828602504696 0.289276036284338 GO:0017070 U6 snRNA binding 5/2792 16/18639 0.3125 2.08620612464183 0.0785828602504696 0.289276036284338 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 5/2792 16/18639 0.3125 2.08620612464183 0.0785828602504696 0.289276036284338 GO:0030159 signaling receptor complex adaptor activity 12/2792 52/18639 0.230769230769231 1.54058298435089 0.0797092431356424 0.292574389544121 GO:0005507 copper ion binding 14/2792 63/18639 0.222222222222222 1.48352435530086 0.0802867172742312 0.293844757747186 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 6/2792 21/18639 0.285714285714286 1.90738845681539 0.0821735645052187 0.298172648347508 GO:0070182 DNA polymerase binding 6/2792 21/18639 0.285714285714286 1.90738845681539 0.0821735645052187 0.298172648347508 GO:0140312 cargo adaptor activity 6/2792 21/18639 0.285714285714286 1.90738845681539 0.0821735645052187 0.298172648347508 GO:0005112 Notch binding 7/2792 26/18639 0.269230769230769 1.79734681507604 0.0826892244137764 0.298338963083796 GO:0120014 phospholipid transfer activity 7/2792 26/18639 0.269230769230769 1.79734681507604 0.0826892244137764 0.298338963083796 GO:0044183 protein folding chaperone 16/2792 75/18639 0.213333333333333 1.42418338108883 0.0875315616130141 0.314646762240258 GO:0051879 Hsp90 protein binding 10/2792 42/18639 0.238095238095238 1.58949038067949 0.0877046880575208 0.314646762240258 GO:0016251 RNA polymerase II general transcription initiation factor activity 12/2792 53/18639 0.226415094339623 1.51151538087257 0.0896368784168966 0.319290821002564 GO:0051018 protein kinase A binding 12/2792 53/18639 0.226415094339623 1.51151538087257 0.0896368784168966 0.319290821002564 GO:0019213 deacetylase activity 9/2792 37/18639 0.243243243243243 1.62385774026175 0.091554827606565 0.319290821002564 GO:0004526 ribonuclease P activity 4/2792 12/18639 0.333333333333333 2.22528653295129 0.0917646847763274 0.319290821002564 GO:0016273 arginine N-methyltransferase activity 4/2792 12/18639 0.333333333333333 2.22528653295129 0.0917646847763274 0.319290821002564 GO:0016274 protein-arginine N-methyltransferase activity 4/2792 12/18639 0.333333333333333 2.22528653295129 0.0917646847763274 0.319290821002564 GO:0035014 phosphatidylinositol 3-kinase regulator activity 4/2792 12/18639 0.333333333333333 2.22528653295129 0.0917646847763274 0.319290821002564 GO:0043047 single-stranded telomeric DNA binding 4/2792 12/18639 0.333333333333333 2.22528653295129 0.0917646847763274 0.319290821002564 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 4/2792 12/18639 0.333333333333333 2.22528653295129 0.0917646847763274 0.319290821002564 GO:0097371 MDM2/MDM4 family protein binding 4/2792 12/18639 0.333333333333333 2.22528653295129 0.0917646847763274 0.319290821002564 GO:0141221 histone deacetylase activity, hydrolytic mechanism 4/2792 12/18639 0.333333333333333 2.22528653295129 0.0917646847763274 0.319290821002564 GO:0140693 molecular condensate scaffold activity 11/2792 48/18639 0.229166666666667 1.52988449140401 0.0945905017285633 0.32804929559411 GO:0051219 phosphoprotein binding 19/2792 93/18639 0.204301075268817 1.3638852943895 0.0950439974673444 0.32804929559411 GO:0043425 bHLH transcription factor binding 8/2792 32/18639 0.25 1.66896489971347 0.0950568037627028 0.32804929559411 GO:0004683 calcium/calmodulin-dependent protein kinase activity 7/2792 27/18639 0.259259259259259 1.73077841451767 0.0978529032075392 0.330653977468276 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 5/2792 17/18639 0.294117647058824 1.96348811730996 0.0981547633901889 0.330653977468276 GO:0004549 tRNA-specific ribonuclease activity 5/2792 17/18639 0.294117647058824 1.96348811730996 0.0981547633901889 0.330653977468276 GO:0004659 prenyltransferase activity 5/2792 17/18639 0.294117647058824 1.96348811730996 0.0981547633901889 0.330653977468276 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 5/2792 17/18639 0.294117647058824 1.96348811730996 0.0981547633901889 0.330653977468276 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 5/2792 17/18639 0.294117647058824 1.96348811730996 0.0981547633901889 0.330653977468276 GO:0046965 nuclear retinoid X receptor binding 5/2792 17/18639 0.294117647058824 1.96348811730996 0.0981547633901889 0.330653977468276 GO:0070402 NADPH binding 5/2792 17/18639 0.294117647058824 1.96348811730996 0.0981547633901889 0.330653977468276 GO:0070403 NAD+ binding 5/2792 17/18639 0.294117647058824 1.96348811730996 0.0981547633901889 0.330653977468276 GO:0008093 cytoskeletal anchor activity 6/2792 22/18639 0.272727272727273 1.8206889815056 0.099299371079601 0.331868950713403 GO:0050321 tau-protein kinase activity 6/2792 22/18639 0.272727272727273 1.8206889815056 0.099299371079601 0.331868950713403 GO:0140035 ubiquitin-like protein reader activity 6/2792 22/18639 0.272727272727273 1.8206889815056 0.099299371079601 0.331868950713403 GO:0004712 protein serine/threonine/tyrosine kinase activity 10/2792 43/18639 0.232558139534884 1.55252548810555 0.0996730000898244 0.332243333632748 GO:0030296 protein tyrosine kinase activator activity 8/2792 33/18639 0.242424242424242 1.61839020578276 0.109809580225361 0.36412054017287 GO:0071889 14-3-3 protein binding 8/2792 33/18639 0.242424242424242 1.61839020578276 0.109809580225361 0.36412054017287 GO:0044325 transmembrane transporter binding 26/2792 136/18639 0.191176470588235 1.27626727625147 0.110320613132279 0.364862444473942 GO:0001223 transcription coactivator binding 10/2792 44/18639 0.227272727272727 1.51724081792133 0.11254495882635 0.371252201842765 GO:0051019 mitogen-activated protein kinase binding 7/2792 28/18639 0.25 1.66896489971347 0.11443176092161 0.375525416977893 GO:0097718 disordered domain specific binding 7/2792 28/18639 0.25 1.66896489971347 0.11443176092161 0.375525416977893 GO:0051015 actin filament binding 38/2792 209/18639 0.181818181818182 1.21379265433707 0.115321509412303 0.377469889055734 GO:0005338 nucleotide-sugar transmembrane transporter activity 4/2792 13/18639 0.307692307692308 2.05411064580119 0.117469312536981 0.379860394692603 GO:0009982 pseudouridine synthase activity 4/2792 13/18639 0.307692307692308 2.05411064580119 0.117469312536981 0.379860394692603 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 4/2792 13/18639 0.307692307692308 2.05411064580119 0.117469312536981 0.379860394692603 GO:0140852 histone ubiquitin ligase activity 4/2792 13/18639 0.307692307692308 2.05411064580119 0.117469312536981 0.379860394692603 GO:0003887 DNA-directed DNA polymerase activity 6/2792 23/18639 0.260869565217391 1.74152859100536 0.118145555829589 0.379860394692603 GO:0008171 O-methyltransferase activity 6/2792 23/18639 0.260869565217391 1.74152859100536 0.118145555829589 0.379860394692603 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 6/2792 23/18639 0.260869565217391 1.74152859100536 0.118145555829589 0.379860394692603 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 14/2792 67/18639 0.208955223880597 1.39495573707394 0.119733746349388 0.383617880106693 GO:0004706 JUN kinase kinase kinase activity 5/2792 18/18639 0.277777777777778 1.85440544412607 0.119918345198706 0.383617880106693 GO:0016853 isomerase activity 33/2792 180/18639 0.183333333333333 1.22390759312321 0.123970422357963 0.395584011041742 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 14/2792 68/18639 0.205882352941176 1.37444168211697 0.13109099642676 0.417029089939743 GO:0004721 phosphoprotein phosphatase activity 32/2792 175/18639 0.182857142857143 1.22072861236185 0.131347744862911 0.417029089939743 GO:0015932 nucleobase-containing compound transmembrane transporter activity 12/2792 57/18639 0.210526315789474 1.4054441260745 0.136563488669167 0.432507807007088 GO:0030291 protein serine/threonine kinase inhibitor activity 10/2792 46/18639 0.217391304347826 1.4512738258378 0.140933417232613 0.445237412650295 GO:0009055 electron transfer activity 22/2792 116/18639 0.189655172413793 1.26611130323091 0.141546436968665 0.446064453970732 GO:0046624 sphingolipid transporter activity 5/2792 19/18639 0.263157894736842 1.75680515759312 0.143712072627834 0.451768149102351 GO:0008474 palmitoyl-(protein) hydrolase activity 4/2792 14/18639 0.285714285714286 1.90738845681539 0.145883511120424 0.451883071031558 GO:0044548 S100 protein binding 4/2792 14/18639 0.285714285714286 1.90738845681539 0.145883511120424 0.451883071031558 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 4/2792 14/18639 0.285714285714286 1.90738845681539 0.145883511120424 0.451883071031558 GO:0098599 palmitoyl hydrolase activity 4/2792 14/18639 0.285714285714286 1.90738845681539 0.145883511120424 0.451883071031558 GO:0098847 sequence-specific single stranded DNA binding 4/2792 14/18639 0.285714285714286 1.90738845681539 0.145883511120424 0.451883071031558 GO:1990825 sequence-specific mRNA binding 4/2792 14/18639 0.285714285714286 1.90738845681539 0.145883511120424 0.451883071031558 GO:0001784 phosphotyrosine residue binding 10/2792 47/18639 0.212765957446809 1.42039565933061 0.156397968700822 0.483273528588916 GO:0016651 oxidoreductase activity, acting on NAD(P)H 17/2792 88/18639 0.193181818181818 1.28965469523313 0.159701991774544 0.490052869488283 GO:0004709 MAP kinase kinase kinase activity 6/2792 25/18639 0.24 1.60220630372493 0.160617755362009 0.490052869488283 GO:0008139 nuclear localization sequence binding 6/2792 25/18639 0.24 1.60220630372493 0.160617755362009 0.490052869488283 GO:0047617 fatty acyl-CoA hydrolase activity 6/2792 25/18639 0.24 1.60220630372493 0.160617755362009 0.490052869488283 GO:0016409 palmitoyltransferase activity 8/2792 36/18639 0.222222222222222 1.48352435530086 0.160907123288672 0.490052869488283 GO:0044390 ubiquitin-like protein conjugating enzyme binding 8/2792 36/18639 0.222222222222222 1.48352435530086 0.160907123288672 0.490052869488283 GO:0045309 protein phosphorylated amino acid binding 12/2792 59/18639 0.203389830508475 1.35780195230926 0.164205423313505 0.498901644995578 GO:0031492 nucleosomal DNA binding 9/2792 42/18639 0.214285714285714 1.43054134261154 0.167681223761707 0.508246191354101 GO:0015095 magnesium ion transmembrane transporter activity 5/2792 20/18639 0.25 1.66896489971347 0.16933969755201 0.510340851317365 GO:0016505 peptidase activator activity involved in apoptotic process 5/2792 20/18639 0.25 1.66896489971347 0.16933969755201 0.510340851317365 GO:0051287 NAD binding 11/2792 54/18639 0.203703703703704 1.35989732569245 0.176328173172331 0.510340851317365 GO:0000774 adenyl-nucleotide exchange factor activity 4/2792 15/18639 0.266666666666667 1.78022922636103 0.176633672348118 0.510340851317365 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 4/2792 15/18639 0.266666666666667 1.78022922636103 0.176633672348118 0.510340851317365 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 4/2792 15/18639 0.266666666666667 1.78022922636103 0.176633672348118 0.510340851317365 GO:0050700 CARD domain binding 4/2792 15/18639 0.266666666666667 1.78022922636103 0.176633672348118 0.510340851317365 GO:0120283 protein serine/threonine kinase binding 4/2792 15/18639 0.266666666666667 1.78022922636103 0.176633672348118 0.510340851317365 GO:0003680 minor groove of adenine-thymine-rich DNA binding 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0004090 carbonyl reductase (NADPH) activity 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0004382 GDP phosphatase activity 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0005345 purine nucleobase transmembrane transporter activity 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0008140 cAMP response element binding protein binding 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0031720 haptoglobin binding 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0032356 oxidized DNA binding 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0033204 ribonuclease P RNA binding 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0043422 protein kinase B binding 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0047429 nucleoside triphosphate diphosphatase activity 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0070513 death domain binding 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0098505 G-rich strand telomeric DNA binding 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 3/2792 10/18639 0.3 2.00275787965616 0.179222062746098 0.510340851317365 GO:0042578 phosphoric ester hydrolase activity 61/2792 363/18639 0.168044077134986 1.12183866537214 0.180660065501869 0.513284749859897 GO:0008143 poly(A) binding 6/2792 26/18639 0.230769230769231 1.54058298435089 0.183996314646479 0.519278488002284 GO:0016289 acyl-CoA hydrolase activity 6/2792 26/18639 0.230769230769231 1.54058298435089 0.183996314646479 0.519278488002284 GO:0097602 cullin family protein binding 6/2792 26/18639 0.230769230769231 1.54058298435089 0.183996314646479 0.519278488002284 GO:0048156 tau protein binding 9/2792 43/18639 0.209302325581395 1.397272939295 0.185683400616029 0.522877868697023 GO:0070717 poly-purine tract binding 7/2792 32/18639 0.21875 1.46034428724928 0.193622301658823 0.544027263510409 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 5/2792 21/18639 0.238095238095238 1.58949038067949 0.196579114129133 0.548693351525272 GO:0035613 RNA stem-loop binding 5/2792 21/18639 0.238095238095238 1.58949038067949 0.196579114129133 0.548693351525272 GO:0072542 protein phosphatase activator activity 5/2792 21/18639 0.238095238095238 1.58949038067949 0.196579114129133 0.548693351525272 GO:0042887 amide transmembrane transporter activity 8/2792 38/18639 0.210526315789474 1.4054441260745 0.200103147353835 0.556085332908906 GO:0043531 ADP binding 8/2792 38/18639 0.210526315789474 1.4054441260745 0.200103147353835 0.556085332908906 GO:0019205 nucleobase-containing compound kinase activity 9/2792 44/18639 0.204545454545455 1.3655167361292 0.204490428504804 0.567036777731661 GO:0008266 poly(U) RNA binding 6/2792 27/18639 0.222222222222222 1.48352435530086 0.208608717914747 0.568019104708223 GO:0035255 ionotropic glutamate receptor binding 6/2792 27/18639 0.222222222222222 1.48352435530086 0.208608717914747 0.568019104708223 GO:0052689 carboxylic ester hydrolase activity 17/2792 92/18639 0.184782608695652 1.23358275196213 0.209214778649551 0.568019104708223 GO:0000062 fatty-acyl-CoA binding 4/2792 16/18639 0.25 1.66896489971347 0.209317276380668 0.568019104708223 GO:0004708 MAP kinase kinase activity 4/2792 16/18639 0.25 1.66896489971347 0.209317276380668 0.568019104708223 GO:0005159 insulin-like growth factor receptor binding 4/2792 16/18639 0.25 1.66896489971347 0.209317276380668 0.568019104708223 GO:0005521 lamin binding 4/2792 16/18639 0.25 1.66896489971347 0.209317276380668 0.568019104708223 GO:0070411 I-SMAD binding 4/2792 16/18639 0.25 1.66896489971347 0.209317276380668 0.568019104708223 GO:0097027 ubiquitin-protein transferase activator activity 4/2792 16/18639 0.25 1.66896489971347 0.209317276380668 0.568019104708223 GO:0140328 floppase activity 4/2792 16/18639 0.25 1.66896489971347 0.209317276380668 0.568019104708223 GO:0000049 tRNA binding 15/2792 80/18639 0.1875 1.2517236747851 0.210624825057779 0.569850725032853 GO:0140223 general transcription initiation factor activity 13/2792 68/18639 0.191176470588235 1.27626727625147 0.210889638397985 0.569850725032853 GO:0008432 JUN kinase binding 3/2792 11/18639 0.272727272727273 1.8206889815056 0.220520538477753 0.585901849093611 GO:0008526 phosphatidylinositol transfer activity 3/2792 11/18639 0.272727272727273 1.8206889815056 0.220520538477753 0.585901849093611 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 3/2792 11/18639 0.272727272727273 1.8206889815056 0.220520538477753 0.585901849093611 GO:0015205 nucleobase transmembrane transporter activity 3/2792 11/18639 0.272727272727273 1.8206889815056 0.220520538477753 0.585901849093611 GO:0019107 myristoyltransferase activity 3/2792 11/18639 0.272727272727273 1.8206889815056 0.220520538477753 0.585901849093611 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 3/2792 11/18639 0.272727272727273 1.8206889815056 0.220520538477753 0.585901849093611 GO:0047676 arachidonate-CoA ligase activity 3/2792 11/18639 0.272727272727273 1.8206889815056 0.220520538477753 0.585901849093611 GO:0140031 phosphorylation-dependent protein binding 3/2792 11/18639 0.272727272727273 1.8206889815056 0.220520538477753 0.585901849093611 GO:0051213 dioxygenase activity 17/2792 93/18639 0.182795698924731 1.22031842129587 0.222592234503097 0.590171477701321 GO:0140303 intramembrane lipid transporter activity 9/2792 45/18639 0.2 1.33517191977077 0.224036566802138 0.592116604848679 GO:0001618 virus receptor activity 15/2792 81/18639 0.185185185185185 1.23627029608405 0.225073429890497 0.592116604848679 GO:0015377 chloride:monoatomic cation symporter activity 5/2792 22/18639 0.227272727272727 1.51724081792133 0.225190803261348 0.592116604848679 GO:0031683 G-protein beta/gamma-subunit complex binding 5/2792 22/18639 0.227272727272727 1.51724081792133 0.225190803261348 0.592116604848679 GO:0016830 carbon-carbon lyase activity 10/2792 51/18639 0.196078431372549 1.30899207820664 0.225807150777332 0.592510498940519 GO:0022853 active monoatomic ion transmembrane transporter activity 21/2792 118/18639 0.177966101694915 1.1880767082706 0.228160607230376 0.597451486974386 GO:0046625 sphingolipid binding 6/2792 28/18639 0.214285714285714 1.43054134261154 0.234293342549239 0.609738821798225 GO:0046875 ephrin receptor binding 6/2792 28/18639 0.214285714285714 1.43054134261154 0.234293342549239 0.609738821798225 GO:0051537 2 iron, 2 sulfur cluster binding 6/2792 28/18639 0.214285714285714 1.43054134261154 0.234293342549239 0.609738821798225 GO:0016831 carboxy-lyase activity 7/2792 34/18639 0.205882352941176 1.37444168211697 0.239638500424531 0.621027772480144 GO:0140272 exogenous protein binding 15/2792 82/18639 0.182926829268293 1.22119382905863 0.239927295111817 0.621027772480144 GO:0071949 FAD binding 8/2792 40/18639 0.2 1.33517191977077 0.24269075584234 0.621027772480144 GO:0097110 scaffold protein binding 13/2792 70/18639 0.185714285714286 1.23980249693 0.242857540702828 0.621027772480144 GO:0015278 intracellularly gated calcium channel activity 4/2792 17/18639 0.235294117647059 1.57079049384797 0.243521126531584 0.621027772480144 GO:0016018 cyclosporin A binding 4/2792 17/18639 0.235294117647059 1.57079049384797 0.243521126531584 0.621027772480144 GO:0032183 SUMO binding 4/2792 17/18639 0.235294117647059 1.57079049384797 0.243521126531584 0.621027772480144 GO:0038191 neuropilin binding 4/2792 17/18639 0.235294117647059 1.57079049384797 0.243521126531584 0.621027772480144 GO:0048038 quinone binding 4/2792 17/18639 0.235294117647059 1.57079049384797 0.243521126531584 0.621027772480144 GO:1901567 fatty acid derivative binding 4/2792 17/18639 0.235294117647059 1.57079049384797 0.243521126531584 0.621027772480144 GO:0042171 lysophosphatidic acid acyltransferase activity 5/2792 23/18639 0.217391304347826 1.4512738258378 0.254925594214615 0.647511009305121 GO:0071617 lysophospholipid acyltransferase activity 5/2792 23/18639 0.217391304347826 1.4512738258378 0.254925594214615 0.647511009305121 GO:0106222 lncRNA binding 6/2792 29/18639 0.206896551724138 1.38121233079735 0.260880837965796 0.659498603448502 GO:0120013 lipid transfer activity 12/2792 65/18639 0.184615384615385 1.23246638748071 0.261407667394423 0.659498603448502 GO:0004126 cytidine deaminase activity 3/2792 12/18639 0.25 1.66896489971347 0.263439156378228 0.659498603448502 GO:0004859 phospholipase inhibitor activity 3/2792 12/18639 0.25 1.66896489971347 0.263439156378228 0.659498603448502 GO:0017166 vinculin binding 3/2792 12/18639 0.25 1.66896489971347 0.263439156378228 0.659498603448502 GO:0070410 co-SMAD binding 3/2792 12/18639 0.25 1.66896489971347 0.263439156378228 0.659498603448502 GO:0097677 STAT family protein binding 3/2792 12/18639 0.25 1.66896489971347 0.263439156378228 0.659498603448502 GO:0034061 DNA polymerase activity 7/2792 35/18639 0.2 1.33517191977077 0.263852326286817 0.659498603448502 GO:0016860 intramolecular oxidoreductase activity 10/2792 53/18639 0.188679245283019 1.25959615072714 0.264318731618337 0.659498603448502 GO:0004713 protein tyrosine kinase activity 24/2792 140/18639 0.171428571428571 1.14443307408923 0.268120976432642 0.667668286437546 GO:0035401 histone H3Y41 kinase activity 20/2792 115/18639 0.173913043478261 1.16101906067024 0.269170206815767 0.667668286437546 GO:0140801 histone H2AXY142 kinase activity 20/2792 115/18639 0.173913043478261 1.16101906067024 0.269170206815767 0.667668286437546 GO:0003774 cytoskeletal motor activity 26/2792 153/18639 0.169934640522876 1.13445980111242 0.272844530742298 0.675463068309392 GO:0008409 5'-3' exonuclease activity 4/2792 18/18639 0.222222222222222 1.48352435530086 0.278836206912406 0.682315959111283 GO:0008525 phosphatidylcholine transporter activity 4/2792 18/18639 0.222222222222222 1.48352435530086 0.278836206912406 0.682315959111283 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 4/2792 18/18639 0.222222222222222 1.48352435530086 0.278836206912406 0.682315959111283 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 4/2792 18/18639 0.222222222222222 1.48352435530086 0.278836206912406 0.682315959111283 GO:0017128 phospholipid scramblase activity 4/2792 18/18639 0.222222222222222 1.48352435530086 0.278836206912406 0.682315959111283 GO:1990381 ubiquitin-specific protease binding 4/2792 18/18639 0.222222222222222 1.48352435530086 0.278836206912406 0.682315959111283 GO:0042625 ATPase-coupled ion transmembrane transporter activity 5/2792 24/18639 0.208333333333333 1.39080408309456 0.285531570222754 0.691793365764279 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 5/2792 24/18639 0.208333333333333 1.39080408309456 0.285531570222754 0.691793365764279 GO:0046961 proton-transporting ATPase activity, rotational mechanism 5/2792 24/18639 0.208333333333333 1.39080408309456 0.285531570222754 0.691793365764279 GO:0060229 lipase activator activity 5/2792 24/18639 0.208333333333333 1.39080408309456 0.285531570222754 0.691793365764279 GO:0008187 poly-pyrimidine tract binding 6/2792 30/18639 0.2 1.33517191977077 0.288197906066898 0.691793365764279 GO:0015215 nucleotide transmembrane transporter activity 6/2792 30/18639 0.2 1.33517191977077 0.288197906066898 0.691793365764279 GO:0031624 ubiquitin conjugating enzyme binding 6/2792 30/18639 0.2 1.33517191977077 0.288197906066898 0.691793365764279 GO:0005484 SNAP receptor activity 7/2792 36/18639 0.194444444444444 1.29808381088825 0.288701168389817 0.691793365764279 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 7/2792 36/18639 0.194444444444444 1.29808381088825 0.288701168389817 0.691793365764279 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 7/2792 36/18639 0.194444444444444 1.29808381088825 0.288701168389817 0.691793365764279 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 7/2792 36/18639 0.194444444444444 1.29808381088825 0.288701168389817 0.691793365764279 GO:0046332 SMAD binding 14/2792 79/18639 0.177215189873418 1.18306372637917 0.290259496439925 0.694217628020159 GO:0140789 histone phosphatase activity 23/2792 136/18639 0.169117647058824 1.12900566745323 0.296860020358098 0.7086695974714 GO:0008173 RNA methyltransferase activity 12/2792 67/18639 0.17910447761194 1.19567634606338 0.297550355717729 0.708984900115415 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 3/2792 13/18639 0.230769230769231 1.54058298435089 0.307230109530602 0.723900258077671 GO:0008253 5'-nucleotidase activity 3/2792 13/18639 0.230769230769231 1.54058298435089 0.307230109530602 0.723900258077671 GO:0019104 DNA N-glycosylase activity 3/2792 13/18639 0.230769230769231 1.54058298435089 0.307230109530602 0.723900258077671 GO:0035673 oligopeptide transmembrane transporter activity 3/2792 13/18639 0.230769230769231 1.54058298435089 0.307230109530602 0.723900258077671 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 3/2792 13/18639 0.230769230769231 1.54058298435089 0.307230109530602 0.723900258077671 GO:0140666 annealing activity 3/2792 13/18639 0.230769230769231 1.54058298435089 0.307230109530602 0.723900258077671 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 4/2792 19/18639 0.210526315789474 1.4054441260745 0.314869309388292 0.731427691638516 GO:0005346 purine ribonucleotide transmembrane transporter activity 4/2792 19/18639 0.210526315789474 1.4054441260745 0.314869309388292 0.731427691638516 GO:0097001 ceramide binding 4/2792 19/18639 0.210526315789474 1.4054441260745 0.314869309388292 0.731427691638516 GO:0120227 acyl-CoA binding 4/2792 19/18639 0.210526315789474 1.4054441260745 0.314869309388292 0.731427691638516 GO:1990380 K48-linked deubiquitinase activity 4/2792 19/18639 0.210526315789474 1.4054441260745 0.314869309388292 0.731427691638516 GO:0005164 tumor necrosis factor receptor binding 6/2792 31/18639 0.193548387096774 1.29210185784268 0.316070739764382 0.731427691638516 GO:0015296 monoatomic anion:monoatomic cation symporter activity 5/2792 25/18639 0.2 1.33517191977077 0.31676002393794 0.731427691638516 GO:0019211 phosphatase activator activity 5/2792 25/18639 0.2 1.33517191977077 0.31676002393794 0.731427691638516 GO:0019706 protein-cysteine S-palmitoyltransferase activity 5/2792 25/18639 0.2 1.33517191977077 0.31676002393794 0.731427691638516 GO:0019707 protein-cysteine S-acyltransferase activity 5/2792 25/18639 0.2 1.33517191977077 0.31676002393794 0.731427691638516 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 5/2792 25/18639 0.2 1.33517191977077 0.31676002393794 0.731427691638516 GO:0016790 thiolester hydrolase activity 8/2792 44/18639 0.181818181818182 1.21379265433707 0.335043748059017 0.772242395707716 GO:0008378 galactosyltransferase activity 6/2792 32/18639 0.1875 1.2517236747851 0.344328071634896 0.779877053638375 GO:0042910 xenobiotic transmembrane transporter activity 6/2792 32/18639 0.1875 1.2517236747851 0.344328071634896 0.779877053638375 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 76/2792 484/18639 0.15702479338843 1.04827547420019 0.344862501208313 0.779877053638375 GO:0008157 protein phosphatase 1 binding 5/2792 26/18639 0.192307692307692 1.28381915362574 0.348370430912097 0.779877053638375 GO:0030247 polysaccharide binding 5/2792 26/18639 0.192307692307692 1.28381915362574 0.348370430912097 0.779877053638375 GO:0070412 R-SMAD binding 5/2792 26/18639 0.192307692307692 1.28381915362574 0.348370430912097 0.779877053638375 GO:0005344 oxygen carrier activity 3/2792 14/18639 0.214285714285714 1.43054134261154 0.351233727278832 0.779877053638375 GO:0005347 ATP transmembrane transporter activity 3/2792 14/18639 0.214285714285714 1.43054134261154 0.351233727278832 0.779877053638375 GO:0008195 phosphatidate phosphatase activity 3/2792 14/18639 0.214285714285714 1.43054134261154 0.351233727278832 0.779877053638375 GO:0008494 translation activator activity 3/2792 14/18639 0.214285714285714 1.43054134261154 0.351233727278832 0.779877053638375 GO:0016530 metallochaperone activity 3/2792 14/18639 0.214285714285714 1.43054134261154 0.351233727278832 0.779877053638375 GO:0030983 mismatched DNA binding 3/2792 14/18639 0.214285714285714 1.43054134261154 0.351233727278832 0.779877053638375 GO:0032454 histone H3K9 demethylase activity 3/2792 14/18639 0.214285714285714 1.43054134261154 0.351233727278832 0.779877053638375 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 3/2792 14/18639 0.214285714285714 1.43054134261154 0.351233727278832 0.779877053638375 GO:0046030 inositol trisphosphate phosphatase activity 3/2792 14/18639 0.214285714285714 1.43054134261154 0.351233727278832 0.779877053638375 GO:0071933 Arp2/3 complex binding 3/2792 14/18639 0.214285714285714 1.43054134261154 0.351233727278832 0.779877053638375 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 4/2792 20/18639 0.2 1.33517191977077 0.351251712347363 0.779877053638375 GO:0016004 phospholipase activator activity 4/2792 20/18639 0.2 1.33517191977077 0.351251712347363 0.779877053638375 GO:0030742 GTP-dependent protein binding 4/2792 20/18639 0.2 1.33517191977077 0.351251712347363 0.779877053638375 GO:0043024 ribosomal small subunit binding 4/2792 20/18639 0.2 1.33517191977077 0.351251712347363 0.779877053638375 GO:0140939 histone H4 methyltransferase activity 4/2792 20/18639 0.2 1.33517191977077 0.351251712347363 0.779877053638375 GO:0015399 primary active transmembrane transporter activity 27/2792 166/18639 0.162650602409639 1.08583258535575 0.352452091806944 0.780196943791937 GO:0003743 translation initiation factor activity 9/2792 51/18639 0.176470588235294 1.17809287038598 0.352624445461868 0.780196943791937 GO:0046915 transition metal ion transmembrane transporter activity 8/2792 45/18639 0.177777777777778 1.18681948424069 0.359045300763207 0.79302179472917 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 7/2792 39/18639 0.179487179487179 1.19823121005069 0.365767866809429 0.806467345222178 GO:0140311 protein sequestering activity 6/2792 33/18639 0.181818181818182 1.21379265433707 0.372803806415611 0.820556038384447 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 5/2792 27/18639 0.185185185185185 1.23627029608405 0.380134456593313 0.83524352919292 GO:0030276 clathrin binding 8/2792 46/18639 0.173913043478261 1.16101906067024 0.383212554307639 0.840552580260278 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 4/2792 21/18639 0.19047619047619 1.27159230454359 0.387645264869299 0.847132349805097 GO:0051010 microtubule plus-end binding 4/2792 21/18639 0.19047619047619 1.27159230454359 0.387645264869299 0.847132349805097 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 21/2792 130/18639 0.161538461538462 1.07840808904562 0.389861154152281 0.847132349805097 GO:0015144 carbohydrate transmembrane transporter activity 7/2792 40/18639 0.175 1.16827542979943 0.391875132772145 0.847132349805097 GO:0050997 quaternary ammonium group binding 7/2792 40/18639 0.175 1.16827542979943 0.391875132772145 0.847132349805097 GO:0004467 long-chain fatty acid-CoA ligase activity 3/2792 15/18639 0.2 1.33517191977077 0.39488374101151 0.847132349805097 GO:0004559 alpha-mannosidase activity 3/2792 15/18639 0.2 1.33517191977077 0.39488374101151 0.847132349805097 GO:0008252 nucleotidase activity 3/2792 15/18639 0.2 1.33517191977077 0.39488374101151 0.847132349805097 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 3/2792 15/18639 0.2 1.33517191977077 0.39488374101151 0.847132349805097 GO:0048531 beta-1,3-galactosyltransferase activity 3/2792 15/18639 0.2 1.33517191977077 0.39488374101151 0.847132349805097 GO:0051371 muscle alpha-actinin binding 3/2792 15/18639 0.2 1.33517191977077 0.39488374101151 0.847132349805097 GO:0061578 K63-linked deubiquitinase activity 3/2792 15/18639 0.2 1.33517191977077 0.39488374101151 0.847132349805097 GO:0140776 protein-containing complex destabilizing activity 3/2792 15/18639 0.2 1.33517191977077 0.39488374101151 0.847132349805097 GO:0001216 DNA-binding transcription activator activity 76/2792 491/18639 0.154786150712831 1.03333061000589 0.39615220984287 0.848420415683719 GO:0008175 tRNA methyltransferase activity 6/2792 34/18639 0.176470588235294 1.17809287038598 0.401339229127985 0.855202719786143 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 6/2792 34/18639 0.176470588235294 1.17809287038598 0.401339229127985 0.855202719786143 GO:0030332 cyclin binding 6/2792 34/18639 0.176470588235294 1.17809287038598 0.401339229127985 0.855202719786143 GO:0051119 sugar transmembrane transporter activity 5/2792 28/18639 0.178571428571429 1.19211778550962 0.411839046602895 0.873181284116321 GO:0051959 dynein light intermediate chain binding 5/2792 28/18639 0.178571428571429 1.19211778550962 0.411839046602895 0.873181284116321 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 5/2792 28/18639 0.178571428571429 1.19211778550962 0.411839046602895 0.873181284116321 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 7/2792 41/18639 0.170731707317073 1.13978090712139 0.417990408035798 0.884746363675772 GO:0008649 rRNA methyltransferase activity 4/2792 22/18639 0.181818181818182 1.21379265433707 0.423746256337732 0.890989644948543 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 4/2792 22/18639 0.181818181818182 1.21379265433707 0.423746256337732 0.890989644948543 GO:0034062 5'-3' RNA polymerase activity 4/2792 22/18639 0.181818181818182 1.21379265433707 0.423746256337732 0.890989644948543 GO:0097747 RNA polymerase activity 4/2792 22/18639 0.181818181818182 1.21379265433707 0.423746256337732 0.890989644948543 GO:0016879 ligase activity, forming carbon-nitrogen bonds 8/2792 48/18639 0.166666666666667 1.11264326647564 0.43166323011633 0.904252921804675 GO:0038187 pattern recognition receptor activity 8/2792 48/18639 0.166666666666667 1.11264326647564 0.43166323011633 0.904252921804675 GO:0015923 mannosidase activity 3/2792 16/18639 0.1875 1.2517236747851 0.437706771310935 0.904252921804675 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 3/2792 16/18639 0.1875 1.2517236747851 0.437706771310935 0.904252921804675 GO:0022858 alanine transmembrane transporter activity 3/2792 16/18639 0.1875 1.2517236747851 0.437706771310935 0.904252921804675 GO:0030275 LRR domain binding 3/2792 16/18639 0.1875 1.2517236747851 0.437706771310935 0.904252921804675 GO:0043023 ribosomal large subunit binding 3/2792 16/18639 0.1875 1.2517236747851 0.437706771310935 0.904252921804675 GO:0055102 lipase inhibitor activity 3/2792 16/18639 0.1875 1.2517236747851 0.437706771310935 0.904252921804675 GO:0140327 flippase activity 3/2792 16/18639 0.1875 1.2517236747851 0.437706771310935 0.904252921804675 GO:0008374 O-acyltransferase activity 9/2792 55/18639 0.163636363636364 1.09241338890336 0.443252297860385 0.904252921804675 GO:0016417 S-acyltransferase activity 5/2792 29/18639 0.172413793103448 1.15101027566446 0.44328867340229 0.904252921804675 GO:0035250 UDP-galactosyltransferase activity 5/2792 29/18639 0.172413793103448 1.15101027566446 0.44328867340229 0.904252921804675 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 5/2792 29/18639 0.172413793103448 1.15101027566446 0.44328867340229 0.904252921804675 GO:0051861 glycolipid binding 5/2792 29/18639 0.172413793103448 1.15101027566446 0.44328867340229 0.904252921804675 GO:0099604 ligand-gated calcium channel activity 5/2792 29/18639 0.172413793103448 1.15101027566446 0.44328867340229 0.904252921804675 GO:0016859 cis-trans isomerase activity 7/2792 42/18639 0.166666666666667 1.11264326647564 0.444001491804422 0.904252921804675 GO:0048487 beta-tubulin binding 7/2792 42/18639 0.166666666666667 1.11264326647564 0.444001491804422 0.904252921804675 GO:0001094 TFIID-class transcription factor complex binding 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:0005337 nucleoside transmembrane transporter activity 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:0005528 FK506 binding 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:0015279 store-operated calcium channel activity 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:0016427 tRNA (cytidine) methyltransferase activity 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:0043121 neurotrophin binding 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:0099122 RNA polymerase II C-terminal domain binding 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:0140940 histone H2A methyltransferase activity 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:1905394 retromer complex binding 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:1990259 histone H2AQ104 methyltransferase activity 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:1990763 arrestin family protein binding 2/2792 10/18639 0.2 1.33517191977077 0.454974501600935 0.904252921804675 GO:0035254 glutamate receptor binding 8/2792 49/18639 0.163265306122449 1.08993626103737 0.45576607020493 0.904410795562907 GO:0000295 adenine nucleotide transmembrane transporter activity 4/2792 23/18639 0.173913043478261 1.16101906067024 0.459287448363652 0.908559282588533 GO:0140102 catalytic activity, acting on a rRNA 4/2792 23/18639 0.173913043478261 1.16101906067024 0.459287448363652 0.908559282588533 GO:0019212 phosphatase inhibitor activity 9/2792 56/18639 0.160714285714286 1.07290600695866 0.465806909576032 0.920022978478321 GO:0008375 acetylglucosaminyltransferase activity 7/2792 43/18639 0.162790697674419 1.08676784167389 0.469803241153299 0.925038939945255 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 7/2792 43/18639 0.162790697674419 1.08676784167389 0.469803241153299 0.925038939945255 GO:0005126 cytokine receptor binding 42/2792 275/18639 0.152727272727273 1.01958582964314 0.471503650407981 0.926949900956867 GO:0008106 alcohol dehydrogenase (NADP+) activity 5/2792 30/18639 0.166666666666667 1.11264326647564 0.474306826869369 0.929364634734762 GO:0070566 adenylyltransferase activity 5/2792 30/18639 0.166666666666667 1.11264326647564 0.474306826869369 0.929364634734762 GO:0002020 protease binding 21/2792 136/18639 0.154411764705882 1.03083126158773 0.476577224421833 0.929364634734762 GO:0005092 GDP-dissociation inhibitor activity 3/2792 17/18639 0.176470588235294 1.17809287038598 0.479317980906511 0.929364634734762 GO:0016805 dipeptidase activity 3/2792 17/18639 0.176470588235294 1.17809287038598 0.479317980906511 0.929364634734762 GO:0017110 nucleoside diphosphate phosphatase activity 3/2792 17/18639 0.176470588235294 1.17809287038598 0.479317980906511 0.929364634734762 GO:0031489 myosin V binding 3/2792 17/18639 0.176470588235294 1.17809287038598 0.479317980906511 0.929364634734762 GO:0032977 membrane insertase activity 3/2792 17/18639 0.176470588235294 1.17809287038598 0.479317980906511 0.929364634734762 GO:0036041 long-chain fatty acid binding 3/2792 17/18639 0.176470588235294 1.17809287038598 0.479317980906511 0.929364634734762 GO:0046982 protein heterodimerization activity 56/2792 369/18639 0.151761517615176 1.0131385841079 0.48011876824372 0.929498225105983 GO:0042805 actinin binding 6/2792 37/18639 0.162162162162162 1.08257182684117 0.485861997537632 0.939185292043824 GO:0004622 lysophospholipase activity 4/2792 24/18639 0.166666666666667 1.11264326647564 0.494038623991832 0.944260609258971 GO:0005315 phosphate transmembrane transporter activity 4/2792 24/18639 0.166666666666667 1.11264326647564 0.494038623991832 0.944260609258971 GO:0015149 hexose transmembrane transporter activity 4/2792 24/18639 0.166666666666667 1.11264326647564 0.494038623991832 0.944260609258971 GO:0030552 cAMP binding 4/2792 24/18639 0.166666666666667 1.11264326647564 0.494038623991832 0.944260609258971 GO:0055056 D-glucose transmembrane transporter activity 4/2792 24/18639 0.166666666666667 1.11264326647564 0.494038623991832 0.944260609258971 GO:0035091 phosphatidylinositol binding 43/2792 284/18639 0.151408450704225 1.0107815589814 0.49517206843403 0.944260609258971 GO:0008327 methyl-CpG binding 5/2792 31/18639 0.161290322580645 1.07675154820224 0.504736843620328 0.944260609258971 GO:0016411 acylglycerol O-acyltransferase activity 5/2792 31/18639 0.161290322580645 1.07675154820224 0.504736843620328 0.944260609258971 GO:0047499 calcium-independent phospholipase A2 activity 5/2792 31/18639 0.161290322580645 1.07675154820224 0.504736843620328 0.944260609258971 GO:0072349 modified amino acid transmembrane transporter activity 5/2792 31/18639 0.161290322580645 1.07675154820224 0.504736843620328 0.944260609258971 GO:0003953 NAD+ nucleosidase activity 2/2792 11/18639 0.181818181818182 1.21379265433707 0.507075382294975 0.944260609258971 GO:0005114 type II transforming growth factor beta receptor binding 2/2792 11/18639 0.181818181818182 1.21379265433707 0.507075382294975 0.944260609258971 GO:0005225 volume-sensitive anion channel activity 2/2792 11/18639 0.181818181818182 1.21379265433707 0.507075382294975 0.944260609258971 GO:0008199 ferric iron binding 2/2792 11/18639 0.181818181818182 1.21379265433707 0.507075382294975 0.944260609258971 GO:0015173 aromatic amino acid transmembrane transporter activity 2/2792 11/18639 0.181818181818182 1.21379265433707 0.507075382294975 0.944260609258971 GO:0015217 ADP transmembrane transporter activity 2/2792 11/18639 0.181818181818182 1.21379265433707 0.507075382294975 0.944260609258971 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 2/2792 11/18639 0.181818181818182 1.21379265433707 0.507075382294975 0.944260609258971 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/2792 11/18639 0.181818181818182 1.21379265433707 0.507075382294975 0.944260609258971 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/2792 11/18639 0.181818181818182 1.21379265433707 0.507075382294975 0.944260609258971 GO:0019864 IgG binding 2/2792 11/18639 0.181818181818182 1.21379265433707 0.507075382294975 0.944260609258971 GO:0032404 mismatch repair complex binding 2/2792 11/18639 0.181818181818182 1.21379265433707 0.507075382294975 0.944260609258971 GO:0032794 GTPase activating protein binding 2/2792 11/18639 0.181818181818182 1.21379265433707 0.507075382294975 0.944260609258971 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 2/2792 11/18639 0.181818181818182 1.21379265433707 0.507075382294975 0.944260609258971 GO:0043522 leucine zipper domain binding 2/2792 11/18639 0.181818181818182 1.21379265433707 0.507075382294975 0.944260609258971 GO:0045294 alpha-catenin binding 2/2792 11/18639 0.181818181818182 1.21379265433707 0.507075382294975 0.944260609258971 GO:0043178 alcohol binding 14/2792 92/18639 0.152173913043478 1.01589167808646 0.519207663331004 0.961597968434069 GO:0031690 adrenergic receptor binding 3/2792 18/18639 0.166666666666667 1.11264326647564 0.519414335705332 0.961597968434069 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 3/2792 18/18639 0.166666666666667 1.11264326647564 0.519414335705332 0.961597968434069 GO:0070628 proteasome binding 3/2792 18/18639 0.166666666666667 1.11264326647564 0.519414335705332 0.961597968434069 GO:0005080 protein kinase C binding 8/2792 52/18639 0.153846153846154 1.0270553229006 0.526606436488767 0.973493703552743 GO:0120020 cholesterol transfer activity 4/2792 25/18639 0.16 1.06813753581662 0.52780597638305 0.974293008730339 GO:0015459 potassium channel regulator activity 9/2792 59/18639 0.152542372881356 1.01835146423195 0.532131521078092 0.978013772539681 GO:0031593 polyubiquitin modification-dependent protein binding 9/2792 59/18639 0.152542372881356 1.01835146423195 0.532131521078092 0.978013772539681 GO:0022884 macromolecule transmembrane transporter activity 5/2792 32/18639 0.15625 1.04310306232092 0.534442171765778 0.978013772539681 GO:0031369 translation initiation factor binding 5/2792 32/18639 0.15625 1.04310306232092 0.534442171765778 0.978013772539681 GO:0120015 sterol transfer activity 5/2792 32/18639 0.15625 1.04310306232092 0.534442171765778 0.978013772539681 GO:0140142 nucleocytoplasmic carrier activity 5/2792 32/18639 0.15625 1.04310306232092 0.534442171765778 0.978013772539681 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 6/2792 39/18639 0.153846153846154 1.0270553229006 0.540066196639477 0.986883553571419 GO:0048306 calcium-dependent protein binding 12/2792 80/18639 0.15 1.00137893982808 0.545981395702045 0.989912223488105 GO:0042277 peptide binding 37/2792 249/18639 0.14859437751004 0.991995201436117 0.548822228722855 0.989912223488105 GO:0004864 protein phosphatase inhibitor activity 8/2792 53/18639 0.150943396226415 1.00767692058172 0.549492470880866 0.989912223488105 GO:0000995 RNA polymerase III general transcription initiation factor activity 2/2792 12/18639 0.166666666666667 1.11264326647564 0.555802627478325 0.989912223488105 GO:0004300 enoyl-CoA hydratase activity 2/2792 12/18639 0.166666666666667 1.11264326647564 0.555802627478325 0.989912223488105 GO:0005049 nuclear export signal receptor activity 2/2792 12/18639 0.166666666666667 1.11264326647564 0.555802627478325 0.989912223488105 GO:0005078 MAP-kinase scaffold activity 2/2792 12/18639 0.166666666666667 1.11264326647564 0.555802627478325 0.989912223488105 GO:0005095 GTPase inhibitor activity 2/2792 12/18639 0.166666666666667 1.11264326647564 0.555802627478325 0.989912223488105 GO:0005165 neurotrophin receptor binding 2/2792 12/18639 0.166666666666667 1.11264326647564 0.555802627478325 0.989912223488105 GO:0005527 macrolide binding 2/2792 12/18639 0.166666666666667 1.11264326647564 0.555802627478325 0.989912223488105 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 2/2792 12/18639 0.166666666666667 1.11264326647564 0.555802627478325 0.989912223488105 GO:0008603 cAMP-dependent protein kinase regulator activity 2/2792 12/18639 0.166666666666667 1.11264326647564 0.555802627478325 0.989912223488105 GO:0036009 protein-glutamine N-methyltransferase activity 2/2792 12/18639 0.166666666666667 1.11264326647564 0.555802627478325 0.989912223488105 GO:0070008 serine-type exopeptidase activity 2/2792 12/18639 0.166666666666667 1.11264326647564 0.555802627478325 0.989912223488105 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 2/2792 12/18639 0.166666666666667 1.11264326647564 0.555802627478325 0.989912223488105 GO:0008301 DNA binding, bending 3/2792 19/18639 0.157894736842105 1.05408309455587 0.557766528139777 0.989912223488105 GO:0031420 alkali metal ion binding 3/2792 19/18639 0.157894736842105 1.05408309455587 0.557766528139777 0.989912223488105 GO:0042577 lipid phosphatase activity 3/2792 19/18639 0.157894736842105 1.05408309455587 0.557766528139777 0.989912223488105 GO:0070003 threonine-type peptidase activity 3/2792 19/18639 0.157894736842105 1.05408309455587 0.557766528139777 0.989912223488105 GO:0004529 DNA exonuclease activity 4/2792 26/18639 0.153846153846154 1.0270553229006 0.560430621014132 0.989912223488105 GO:0005160 transforming growth factor beta receptor binding 4/2792 26/18639 0.153846153846154 1.0270553229006 0.560430621014132 0.989912223488105 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 4/2792 26/18639 0.153846153846154 1.0270553229006 0.560430621014132 0.989912223488105 GO:0015145 monosaccharide transmembrane transporter activity 4/2792 26/18639 0.153846153846154 1.0270553229006 0.560430621014132 0.989912223488105 GO:0015216 purine nucleotide transmembrane transporter activity 4/2792 26/18639 0.153846153846154 1.0270553229006 0.560430621014132 0.989912223488105 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 5/2792 33/18639 0.151515151515152 1.01149387861422 0.563306165578308 0.992231387357075 GO:0019239 deaminase activity 5/2792 33/18639 0.151515151515152 1.01149387861422 0.563306165578308 0.992231387357075 GO:0140359 ABC-type transporter activity 7/2792 47/18639 0.148936170212766 0.994276961531427 0.569095395762449 0.999999999999985 GO:0050661 NADP binding 8/2792 54/18639 0.148148148148148 0.98901623686724 0.571911391994454 0.999999999999985 GO:0032934 sterol binding 10/2792 68/18639 0.147058823529412 0.981744058654981 0.577323123189328 0.999999999999985 GO:0015078 proton transmembrane transporter activity 27/2792 185/18639 0.145945945945946 0.974314644157051 0.590311224975026 0.999999999999985 GO:0008376 acetylgalactosaminyltransferase activity 5/2792 34/18639 0.147058823529412 0.981744058654981 0.591231499449054 0.999999999999985 GO:0015035 protein-disulfide reductase activity 5/2792 34/18639 0.147058823529412 0.981744058654981 0.591231499449054 0.999999999999985 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 5/2792 34/18639 0.147058823529412 0.981744058654981 0.591231499449054 0.999999999999985 GO:0051427 hormone receptor binding 5/2792 34/18639 0.147058823529412 0.981744058654981 0.591231499449054 0.999999999999985 GO:0090482 vitamin transmembrane transporter activity 5/2792 34/18639 0.147058823529412 0.981744058654981 0.591231499449054 0.999999999999985 GO:0042169 SH2 domain binding 6/2792 41/18639 0.146341463414634 0.976955063246908 0.591627929905456 0.999999999999985 GO:0008320 protein transmembrane transporter activity 4/2792 27/18639 0.148148148148148 0.98901623686724 0.591786475696013 0.999999999999985 GO:0016405 CoA-ligase activity 4/2792 27/18639 0.148148148148148 0.98901623686724 0.591786475696013 0.999999999999985 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 4/2792 27/18639 0.148148148148148 0.98901623686724 0.591786475696013 0.999999999999985 GO:0032266 phosphatidylinositol-3-phosphate binding 7/2792 48/18639 0.145833333333333 0.973562858166189 0.592559424043493 0.999999999999985 GO:0005543 phospholipid binding 73/2792 497/18639 0.146881287726358 0.980558854560025 0.592808354333599 0.999999999999985 GO:0140313 molecular sequestering activity 8/2792 55/18639 0.145454545454545 0.971034123469654 0.593810812272593 0.999999999999985 GO:0004857 enzyme inhibitor activity 61/2792 416/18639 0.146634615384615 0.97891210463963 0.593830539983618 0.999999999999985 GO:0016408 C-acyltransferase activity 3/2792 20/18639 0.15 1.00137893982808 0.594210319161968 0.999999999999985 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 3/2792 20/18639 0.15 1.00137893982808 0.594210319161968 0.999999999999985 GO:0061608 nuclear import signal receptor activity 3/2792 20/18639 0.15 1.00137893982808 0.594210319161968 0.999999999999985 GO:0140664 ATP-dependent DNA damage sensor activity 3/2792 20/18639 0.15 1.00137893982808 0.594210319161968 0.999999999999985 GO:0051536 iron-sulfur cluster binding 11/2792 76/18639 0.144736842105263 0.966242836676218 0.598490029101235 0.999999999999985 GO:0005035 death receptor activity 2/2792 13/18639 0.153846153846154 1.0270553229006 0.600997630741547 0.999999999999985 GO:0005172 vascular endothelial growth factor receptor binding 2/2792 13/18639 0.153846153846154 1.0270553229006 0.600997630741547 0.999999999999985 GO:0005542 folic acid binding 2/2792 13/18639 0.153846153846154 1.0270553229006 0.600997630741547 0.999999999999985 GO:0019855 calcium channel inhibitor activity 2/2792 13/18639 0.153846153846154 1.0270553229006 0.600997630741547 0.999999999999985 GO:0061459 L-arginine transmembrane transporter activity 2/2792 13/18639 0.153846153846154 1.0270553229006 0.600997630741547 0.999999999999985 GO:0070700 BMP receptor binding 2/2792 13/18639 0.153846153846154 1.0270553229006 0.600997630741547 0.999999999999985 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/2792 13/18639 0.153846153846154 1.0270553229006 0.600997630741547 0.999999999999985 GO:0089720 caspase binding 2/2792 13/18639 0.153846153846154 1.0270553229006 0.600997630741547 0.999999999999985 GO:0140333 glycerophospholipid flippase activity 2/2792 13/18639 0.153846153846154 1.0270553229006 0.600997630741547 0.999999999999985 GO:0140410 monoatomic cation:bicarbonate symporter activity 2/2792 13/18639 0.153846153846154 1.0270553229006 0.600997630741547 0.999999999999985 GO:0070851 growth factor receptor binding 20/2792 139/18639 0.143884892086331 0.960555337964585 0.614073792719283 0.999999999999985 GO:0051540 metal cluster binding 11/2792 77/18639 0.142857142857143 0.953694228407695 0.616672836401865 0.999999999999985 GO:0004623 phospholipase A2 activity 5/2792 35/18639 0.142857142857143 0.953694228407695 0.618139283485053 0.999999999999985 GO:0051393 alpha-actinin binding 4/2792 28/18639 0.142857142857143 0.953694228407695 0.6217777138782 0.999999999999985 GO:0005200 structural constituent of cytoskeleton 16/2792 112/18639 0.142857142857143 0.953694228407695 0.622198200744078 0.999999999999985 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 26/2792 181/18639 0.143646408839779 0.958963257293926 0.623952011021329 0.999999999999985 GO:0010314 phosphatidylinositol-5-phosphate binding 3/2792 21/18639 0.142857142857143 0.953694228407695 0.628637828210746 0.999999999999985 GO:0070279 vitamin B6 binding 8/2792 57/18639 0.140350877192982 0.936962750716332 0.635873763992797 0.999999999999985 GO:0000149 SNARE binding 15/2792 106/18639 0.141509433962264 0.944697113045359 0.636188355667064 0.999999999999985 GO:0004705 JUN kinase activity 2/2792 14/18639 0.142857142857143 0.953694228407695 0.642624947985333 0.999999999999985 GO:0005161 platelet-derived growth factor receptor binding 2/2792 14/18639 0.142857142857143 0.953694228407695 0.642624947985333 0.999999999999985 GO:0005545 1-phosphatidylinositol binding 2/2792 14/18639 0.142857142857143 0.953694228407695 0.642624947985333 0.999999999999985 GO:0008559 ABC-type xenobiotic transporter activity 2/2792 14/18639 0.142857142857143 0.953694228407695 0.642624947985333 0.999999999999985 GO:0015926 glucosidase activity 2/2792 14/18639 0.142857142857143 0.953694228407695 0.642624947985333 0.999999999999985 GO:0019763 immunoglobulin receptor activity 2/2792 14/18639 0.142857142857143 0.953694228407695 0.642624947985333 0.999999999999985 GO:0019992 diacylglycerol binding 2/2792 14/18639 0.142857142857143 0.953694228407695 0.642624947985333 0.999999999999985 GO:0031404 chloride ion binding 2/2792 14/18639 0.142857142857143 0.953694228407695 0.642624947985333 0.999999999999985 GO:0034236 protein kinase A catalytic subunit binding 2/2792 14/18639 0.142857142857143 0.953694228407695 0.642624947985333 0.999999999999985 GO:0043176 amine binding 2/2792 14/18639 0.142857142857143 0.953694228407695 0.642624947985333 0.999999999999985 GO:0004033 aldo-keto reductase (NADPH) activity 5/2792 36/18639 0.138888888888889 0.927202722063037 0.643967954917851 0.999999999999985 GO:0050660 flavin adenine dinucleotide binding 12/2792 86/18639 0.13953488372093 0.93151529286333 0.651237145994168 0.999999999999985 GO:0016835 carbon-oxygen lyase activity 11/2792 79/18639 0.139240506329114 0.929550070726488 0.651763898624039 0.999999999999985 GO:0008970 phospholipase A1 activity 3/2792 22/18639 0.136363636363636 0.9103444907528 0.660989129032801 0.999999999999985 GO:0016881 acid-amino acid ligase activity 3/2792 22/18639 0.136363636363636 0.9103444907528 0.660989129032801 0.999999999999985 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/2792 22/18639 0.136363636363636 0.9103444907528 0.660989129032801 0.999999999999985 GO:0016248 channel inhibitor activity 6/2792 44/18639 0.136363636363636 0.9103444907528 0.662821697215637 0.999999999999985 GO:0043014 alpha-tubulin binding 6/2792 44/18639 0.136363636363636 0.9103444907528 0.662821697215637 0.999999999999985 GO:0022829 wide pore channel activity 5/2792 37/18639 0.135135135135135 0.902143189034306 0.66867201075851 0.999999999999985 GO:0030551 cyclic nucleotide binding 5/2792 37/18639 0.135135135135135 0.902143189034306 0.66867201075851 0.999999999999985 GO:1901981 phosphatidylinositol phosphate binding 26/2792 185/18639 0.140540540540541 0.938228916595679 0.669596341972618 0.999999999999985 GO:0001965 G-protein alpha-subunit binding 4/2792 30/18639 0.133333333333333 0.890114613180516 0.677417365505881 0.999999999999985 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 4/2792 30/18639 0.133333333333333 0.890114613180516 0.677417365505881 0.999999999999985 GO:0031210 phosphatidylcholine binding 4/2792 30/18639 0.133333333333333 0.890114613180516 0.677417365505881 0.999999999999985 GO:0016798 hydrolase activity, acting on glycosyl bonds 18/2792 130/18639 0.138461538461538 0.924349790610536 0.678791817377515 0.999999999999985 GO:0015556 C4-dicarboxylate transmembrane transporter activity 2/2792 15/18639 0.133333333333333 0.890114613180516 0.680738979827459 0.999999999999985 GO:0015929 hexosaminidase activity 2/2792 15/18639 0.133333333333333 0.890114613180516 0.680738979827459 0.999999999999985 GO:0017081 chloride channel regulator activity 2/2792 15/18639 0.133333333333333 0.890114613180516 0.680738979827459 0.999999999999985 GO:0031005 filamin binding 2/2792 15/18639 0.133333333333333 0.890114613180516 0.680738979827459 0.999999999999985 GO:0034483 heparan sulfate sulfotransferase activity 2/2792 15/18639 0.133333333333333 0.890114613180516 0.680738979827459 0.999999999999985 GO:0045504 dynein heavy chain binding 2/2792 15/18639 0.133333333333333 0.890114613180516 0.680738979827459 0.999999999999985 GO:0047372 monoacylglycerol lipase activity 2/2792 15/18639 0.133333333333333 0.890114613180516 0.680738979827459 0.999999999999985 GO:0050780 dopamine receptor binding 2/2792 15/18639 0.133333333333333 0.890114613180516 0.680738979827459 0.999999999999985 GO:0140161 monocarboxylate:sodium symporter activity 2/2792 15/18639 0.133333333333333 0.890114613180516 0.680738979827459 0.999999999999985 GO:0141110 transporter inhibitor activity 6/2792 45/18639 0.133333333333333 0.890114613180516 0.684733110098656 0.999999999999985 GO:0030971 receptor tyrosine kinase binding 11/2792 81/18639 0.135802469135802 0.906598217128303 0.685012787759124 0.999999999999985 GO:0005158 insulin receptor binding 3/2792 23/18639 0.130434782608696 0.870764295502678 0.691244381133173 0.999999999999985 GO:0017134 fibroblast growth factor binding 3/2792 23/18639 0.130434782608696 0.870764295502678 0.691244381133173 0.999999999999985 GO:0043274 phospholipase binding 3/2792 23/18639 0.130434782608696 0.870764295502678 0.691244381133173 0.999999999999985 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 3/2792 23/18639 0.130434782608696 0.870764295502678 0.691244381133173 0.999999999999985 GO:0000146 microfilament motor activity 5/2792 38/18639 0.131578947368421 0.878402578796562 0.692220638301722 0.999999999999985 GO:1990782 protein tyrosine kinase binding 16/2792 117/18639 0.136752136752137 0.912938064800529 0.692906955691286 0.999999999999985 GO:0016874 ligase activity 23/2792 167/18639 0.137724550898204 0.919429765111611 0.701943036804416 0.999999999999985 GO:0016878 acid-thiol ligase activity 4/2792 31/18639 0.129032258064516 0.861401238561789 0.702999665044481 0.999999999999985 GO:0070273 phosphatidylinositol-4-phosphate binding 4/2792 31/18639 0.129032258064516 0.861401238561789 0.702999665044481 0.999999999999985 GO:0019905 syntaxin binding 8/2792 61/18639 0.131147540983607 0.875522570341491 0.712159753338321 0.999999999999985 GO:0016776 phosphotransferase activity, phosphate group as acceptor 5/2792 39/18639 0.128205128205128 0.855879435750496 0.714596291487346 0.999999999999985 GO:0003688 DNA replication origin binding 2/2792 16/18639 0.125 0.834482449856733 0.715457866758392 0.999999999999985 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 2/2792 16/18639 0.125 0.834482449856733 0.715457866758392 0.999999999999985 GO:0004707 MAP kinase activity 2/2792 16/18639 0.125 0.834482449856733 0.715457866758392 0.999999999999985 GO:0005149 interleukin-1 receptor binding 2/2792 16/18639 0.125 0.834482449856733 0.715457866758392 0.999999999999985 GO:0008142 oxysterol binding 2/2792 16/18639 0.125 0.834482449856733 0.715457866758392 0.999999999999985 GO:0015378 sodium:chloride symporter activity 2/2792 16/18639 0.125 0.834482449856733 0.715457866758392 0.999999999999985 GO:0015562 efflux transmembrane transporter activity 2/2792 16/18639 0.125 0.834482449856733 0.715457866758392 0.999999999999985 GO:0034450 ubiquitin-ubiquitin ligase activity 2/2792 16/18639 0.125 0.834482449856733 0.715457866758392 0.999999999999985 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/2792 16/18639 0.125 0.834482449856733 0.715457866758392 0.999999999999985 GO:0015485 cholesterol binding 7/2792 54/18639 0.12962962962963 0.865389207258835 0.718051688536364 0.999999999999985 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 7/2792 54/18639 0.12962962962963 0.865389207258835 0.718051688536364 0.999999999999985 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 7/2792 54/18639 0.12962962962963 0.865389207258835 0.718051688536364 0.999999999999985 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/2792 24/18639 0.125 0.834482449856733 0.719416632153365 0.999999999999985 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/2792 24/18639 0.125 0.834482449856733 0.719416632153365 0.999999999999985 GO:0030215 semaphorin receptor binding 3/2792 24/18639 0.125 0.834482449856733 0.719416632153365 0.999999999999985 GO:0050699 WW domain binding 3/2792 24/18639 0.125 0.834482449856733 0.719416632153365 0.999999999999985 GO:0070840 dynein complex binding 3/2792 24/18639 0.125 0.834482449856733 0.719416632153365 0.999999999999985 GO:0140612 DNA damage sensor activity 3/2792 24/18639 0.125 0.834482449856733 0.719416632153365 0.999999999999985 GO:0017022 myosin binding 10/2792 76/18639 0.131578947368421 0.878402578796562 0.719815497081676 0.999999999999985 GO:0042626 ATPase-coupled transmembrane transporter activity 13/2792 98/18639 0.13265306122449 0.88557321209286 0.724967173370021 0.999999999999985 GO:0047498 calcium-dependent phospholipase A2 activity 4/2792 32/18639 0.125 0.834482449856733 0.727079306941439 0.999999999999985 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 12/2792 91/18639 0.131868131868132 0.880333133914796 0.727791220821639 0.999999999999985 GO:0015179 L-amino acid transmembrane transporter activity 8/2792 62/18639 0.129032258064516 0.861401238561789 0.729478144603323 0.999999999999985 GO:0051117 ATPase binding 11/2792 84/18639 0.130952380952381 0.874219709373721 0.731163033780323 0.999999999999985 GO:0015036 disulfide oxidoreductase activity 5/2792 40/18639 0.125 0.834482449856733 0.735793253006773 0.999999999999985 GO:0005319 lipid transporter activity 24/2792 178/18639 0.134831460674157 0.900115900969061 0.743411749394417 0.999999999999985 GO:0008483 transaminase activity 3/2792 25/18639 0.12 0.801103151862464 0.745545357940226 0.999999999999985 GO:0015645 fatty acid ligase activity 3/2792 25/18639 0.12 0.801103151862464 0.745545357940226 0.999999999999985 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 3/2792 25/18639 0.12 0.801103151862464 0.745545357940226 0.999999999999985 GO:0120515 fatty acid-CoA ligase activity 3/2792 25/18639 0.12 0.801103151862464 0.745545357940226 0.999999999999985 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/2792 17/18639 0.117647058823529 0.785395246923985 0.746943184871975 0.999999999999985 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/2792 17/18639 0.117647058823529 0.785395246923985 0.746943184871975 0.999999999999985 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/2792 17/18639 0.117647058823529 0.785395246923985 0.746943184871975 0.999999999999985 GO:0008429 phosphatidylethanolamine binding 2/2792 17/18639 0.117647058823529 0.785395246923985 0.746943184871975 0.999999999999985 GO:0019198 transmembrane receptor protein phosphatase activity 2/2792 17/18639 0.117647058823529 0.785395246923985 0.746943184871975 0.999999999999985 GO:0045236 CXCR chemokine receptor binding 2/2792 17/18639 0.117647058823529 0.785395246923985 0.746943184871975 0.999999999999985 GO:0016829 lyase activity 27/2792 200/18639 0.135 0.901241045845272 0.750753297739348 0.999999999999985 GO:0030170 pyridoxal phosphate binding 7/2792 56/18639 0.125 0.834482449856733 0.753459485887137 0.999999999999985 GO:0016877 ligase activity, forming carbon-sulfur bonds 5/2792 41/18639 0.121951219512195 0.814129219372423 0.755816214548622 0.999999999999985 GO:0016209 antioxidant activity 11/2792 86/18639 0.127906976744186 0.853889018458053 0.759342208207514 0.999999999999985 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/2792 26/18639 0.115384615384615 0.770291492175446 0.769690758408847 0.999999999999985 GO:0008198 ferrous iron binding 3/2792 26/18639 0.115384615384615 0.770291492175446 0.769690758408847 0.999999999999985 GO:0043548 phosphatidylinositol 3-kinase binding 3/2792 26/18639 0.115384615384615 0.770291492175446 0.769690758408847 0.999999999999985 GO:0019825 oxygen binding 4/2792 34/18639 0.117647058823529 0.785395246923985 0.770793666590292 0.999999999999985 GO:0019894 kinesin binding 5/2792 42/18639 0.119047619047619 0.794745190339746 0.774678900804432 0.999999999999985 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/2792 18/18639 0.111111111111111 0.74176217765043 0.775384291017806 0.999999999999985 GO:0008308 voltage-gated monoatomic anion channel activity 2/2792 18/18639 0.111111111111111 0.74176217765043 0.775384291017806 0.999999999999985 GO:0015172 acidic amino acid transmembrane transporter activity 2/2792 18/18639 0.111111111111111 0.74176217765043 0.775384291017806 0.999999999999985 GO:0015373 monoatomic anion:sodium symporter activity 2/2792 18/18639 0.111111111111111 0.74176217765043 0.775384291017806 0.999999999999985 GO:0016854 racemase and epimerase activity 2/2792 18/18639 0.111111111111111 0.74176217765043 0.775384291017806 0.999999999999985 GO:0017075 syntaxin-1 binding 2/2792 18/18639 0.111111111111111 0.74176217765043 0.775384291017806 0.999999999999985 GO:0032393 MHC class I receptor activity 2/2792 18/18639 0.111111111111111 0.74176217765043 0.775384291017806 0.999999999999985 GO:0050811 GABA receptor binding 2/2792 18/18639 0.111111111111111 0.74176217765043 0.775384291017806 0.999999999999985 GO:0070064 proline-rich region binding 2/2792 18/18639 0.111111111111111 0.74176217765043 0.775384291017806 0.999999999999985 GO:1901611 phosphatidylglycerol binding 2/2792 18/18639 0.111111111111111 0.74176217765043 0.775384291017806 0.999999999999985 GO:0015101 organic cation transmembrane transporter activity 10/2792 81/18639 0.123456790123457 0.824180197389366 0.791021297688904 0.999999999999985 GO:0005385 zinc ion transmembrane transporter activity 3/2792 27/18639 0.111111111111111 0.74176217765043 0.791928793747951 0.999999999999985 GO:0015252 proton channel activity 3/2792 27/18639 0.111111111111111 0.74176217765043 0.791928793747951 0.999999999999985 GO:0008200 ion channel inhibitor activity 5/2792 43/18639 0.116279069767442 0.776262744052775 0.792402756841743 0.999999999999985 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 11/2792 89/18639 0.123595505617978 0.825106242554972 0.797672751121157 0.999999999999985 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 11/2792 89/18639 0.123595505617978 0.825106242554972 0.797672751121157 0.999999999999985 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 7/2792 59/18639 0.11864406779661 0.792051138847069 0.800393724157968 0.999999999999985 GO:0070888 E-box binding 7/2792 59/18639 0.11864406779661 0.792051138847069 0.800393724157968 0.999999999999985 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 2/2792 19/18639 0.105263157894737 0.702722063037249 0.800986380768162 0.999999999999985 GO:0005229 intracellularly calcium-gated chloride channel activity 2/2792 19/18639 0.105263157894737 0.702722063037249 0.800986380768162 0.999999999999985 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/2792 19/18639 0.105263157894737 0.702722063037249 0.800986380768162 0.999999999999985 GO:0050145 nucleoside monophosphate kinase activity 2/2792 19/18639 0.105263157894737 0.702722063037249 0.800986380768162 0.999999999999985 GO:0141147 intracellularly calcium-gated channel activity 2/2792 19/18639 0.105263157894737 0.702722063037249 0.800986380768162 0.999999999999985 GO:0000182 rDNA binding 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0003796 lysozyme activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0004955 prostaglandin receptor activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0005031 tumor necrosis factor receptor activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0005381 iron ion transmembrane transporter activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0005522 profilin binding 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0008239 dipeptidyl-peptidase activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0008519 ammonium channel activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0015203 polyamine transmembrane transporter activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0019911 structural constituent of myelin sheath 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0031419 cobalamin binding 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0042166 acetylcholine binding 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0043208 glycosphingolipid binding 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0043295 glutathione binding 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0050308 sugar-phosphatase activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0050815 phosphoserine residue binding 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0070739 protein-glutamic acid ligase activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0070740 tubulin-glutamic acid ligase activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0071723 lipopeptide binding 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0097177 mitochondrial ribosome binding 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0141109 transporter activator activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:1990757 ubiquitin ligase activator activity 1/2792 10/18639 0.1 0.667585959885387 0.80273061283321 0.999999999999985 GO:0140375 immune receptor activity 20/2792 156/18639 0.128205128205128 0.855879435750496 0.806607514903133 0.999999999999985 GO:0045505 dynein intermediate chain binding 4/2792 36/18639 0.111111111111111 0.74176217765043 0.808806387774301 0.999999999999985 GO:0140793 histone H2AXY142 phosphatase activity 11/2792 90/18639 0.122222222222222 0.815938395415473 0.809407407132388 0.999999999999985 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 6/2792 52/18639 0.115384615384615 0.770291492175446 0.811180595663745 0.999999999999985 GO:0045499 chemorepellent activity 3/2792 28/18639 0.107142857142857 0.715270671305772 0.812346923332322 0.999999999999985 GO:0050698 proteoglycan sulfotransferase activity 3/2792 28/18639 0.107142857142857 0.715270671305772 0.812346923332322 0.999999999999985 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 7/2792 60/18639 0.116666666666667 0.778850286532951 0.814429041019669 0.999999999999985 GO:0098531 ligand-modulated transcription factor activity 7/2792 60/18639 0.116666666666667 0.778850286532951 0.814429041019669 0.999999999999985 GO:0001614 purinergic nucleotide receptor activity 2/2792 20/18639 0.1 0.667585959885387 0.823961498724406 0.999999999999985 GO:0001972 retinoic acid binding 2/2792 20/18639 0.1 0.667585959885387 0.823961498724406 0.999999999999985 GO:0016502 nucleotide receptor activity 2/2792 20/18639 0.1 0.667585959885387 0.823961498724406 0.999999999999985 GO:0008009 chemokine activity 5/2792 45/18639 0.111111111111111 0.74176217765043 0.82455103859224 0.999999999999985 GO:0005246 calcium channel regulator activity 6/2792 53/18639 0.113207547169811 0.755757690436287 0.825487789660605 0.999999999999985 GO:0008146 sulfotransferase activity 6/2792 53/18639 0.113207547169811 0.755757690436287 0.825487789660605 0.999999999999985 GO:0016836 hydro-lyase activity 7/2792 61/18639 0.114754098360656 0.766082249048805 0.827686170904288 0.999999999999985 GO:0016757 glycosyltransferase activity 35/2792 267/18639 0.131086142322097 0.875112681497698 0.8283284287135 0.999999999999985 GO:0004629 phospholipase C activity 3/2792 29/18639 0.103448275862069 0.690606165398676 0.831040495983627 0.999999999999985 GO:0043236 laminin binding 3/2792 29/18639 0.103448275862069 0.690606165398676 0.831040495983627 0.999999999999985 GO:0000099 sulfur amino acid transmembrane transporter activity 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0001851 complement component C3b binding 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0002162 dystroglycan binding 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0004954 prostanoid receptor activity 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0005536 D-glucose binding 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0008046 axon guidance receptor activity 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0008172 S-methyltransferase activity 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0008503 benzodiazepine receptor activity 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0010854 adenylate cyclase regulator activity 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0019203 carbohydrate phosphatase activity 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0019215 intermediate filament binding 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0031731 CCR6 chemokine receptor binding 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0032050 clathrin heavy chain binding 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0034056 estrogen response element binding 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0034713 type I transforming growth factor beta receptor binding 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0042608 T cell receptor binding 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0048185 activin binding 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0180030 inositol phosphate kinase activity 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:1900750 oligopeptide binding 1/2792 11/18639 0.0909090909090909 0.606896327168533 0.832296135887033 0.999999999999985 GO:0004180 carboxypeptidase activity 5/2792 46/18639 0.108695652173913 0.725636912918899 0.839046286178651 0.999999999999985 GO:0005496 steroid binding 13/2792 108/18639 0.12037037037037 0.803575692454632 0.840257702579866 0.999999999999985 GO:0008028 monocarboxylic acid transmembrane transporter activity 8/2792 70/18639 0.114285714285714 0.762955382726156 0.842322617654802 0.999999999999985 GO:0001846 opsonin binding 2/2792 21/18639 0.0952380952380952 0.635796152271797 0.844521885094265 0.999999999999985 GO:0008373 sialyltransferase activity 2/2792 21/18639 0.0952380952380952 0.635796152271797 0.844521885094265 0.999999999999985 GO:0015174 basic amino acid transmembrane transporter activity 2/2792 21/18639 0.0952380952380952 0.635796152271797 0.844521885094265 0.999999999999985 GO:1904047 S-adenosyl-L-methionine binding 2/2792 21/18639 0.0952380952380952 0.635796152271797 0.844521885094265 0.999999999999985 GO:0016769 transferase activity, transferring nitrogenous groups 3/2792 30/18639 0.1 0.667585959885387 0.848109732703376 0.999999999999985 GO:0033612 receptor serine/threonine kinase binding 3/2792 30/18639 0.1 0.667585959885387 0.848109732703376 0.999999999999985 GO:1901682 sulfur compound transmembrane transporter activity 7/2792 63/18639 0.111111111111111 0.74176217765043 0.851949172029897 0.999999999999985 GO:0061749 forked DNA-dependent helicase activity 5/2792 47/18639 0.106382978723404 0.710197829665305 0.852542336451202 0.999999999999985 GO:1990518 single-stranded 3'-5' DNA helicase activity 5/2792 47/18639 0.106382978723404 0.710197829665305 0.852542336451202 0.999999999999985 GO:0003720 telomerase activity 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0003995 acyl-CoA dehydrogenase activity 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0004000 adenosine deaminase activity 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0004875 complement receptor activity 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0005247 voltage-gated chloride channel activity 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0005436 sodium:phosphate symporter activity 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0008504 monoamine transmembrane transporter activity 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0015368 calcium:monoatomic cation antiporter activity 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0016208 AMP binding 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0016423 tRNA (guanine) methyltransferase activity 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0016801 hydrolase activity, acting on ether bonds 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0016803 ether hydrolase activity 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0016840 carbon-nitrogen lyase activity 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0031543 peptidyl-proline dioxygenase activity 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0034452 dynactin binding 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0035251 UDP-glucosyltransferase activity 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0042301 phosphate ion binding 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0045295 gamma-catenin binding 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:1990459 transferrin receptor binding 1/2792 12/18639 0.0833333333333333 0.556321633237822 0.857431909378734 0.999999999999985 GO:0140784 metal ion sensor activity 2/2792 22/18639 0.0909090909090909 0.606896327168533 0.862875160700411 0.999999999999985 GO:0005310 dicarboxylic acid transmembrane transporter activity 3/2792 31/18639 0.0967741935483871 0.646050928921342 0.863657239952544 0.999999999999985 GO:0005452 solute:inorganic anion antiporter activity 3/2792 31/18639 0.0967741935483871 0.646050928921342 0.863657239952544 0.999999999999985 GO:0042379 chemokine receptor binding 8/2792 72/18639 0.111111111111111 0.74176217765043 0.86376257500905 0.999999999999985 GO:0009378 four-way junction helicase activity 5/2792 48/18639 0.104166666666667 0.695402041547278 0.865082536917782 0.999999999999985 GO:0036121 double-stranded DNA helicase activity 5/2792 48/18639 0.104166666666667 0.695402041547278 0.865082536917782 0.999999999999985 GO:0043138 3'-5' DNA helicase activity 5/2792 48/18639 0.104166666666667 0.695402041547278 0.865082536917782 0.999999999999985 GO:0004896 cytokine receptor activity 11/2792 96/18639 0.114583333333333 0.764942245702006 0.869362628101233 0.999999999999985 GO:0004177 aminopeptidase activity 4/2792 40/18639 0.1 0.667585959885387 0.869368239275373 0.999999999999985 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 4/2792 40/18639 0.1 0.667585959885387 0.869368239275373 0.999999999999985 GO:0004601 peroxidase activity 6/2792 57/18639 0.105263157894737 0.702722063037249 0.874244665570533 0.999999999999985 GO:0015106 bicarbonate transmembrane transporter activity 3/2792 32/18639 0.09375 0.62586183739255 0.877785991643348 0.999999999999985 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/2792 32/18639 0.09375 0.62586183739255 0.877785991643348 0.999999999999985 GO:0002161 aminoacyl-tRNA editing activity 1/2792 13/18639 0.0769230769230769 0.513527661450298 0.8788014325985 0.999999999999985 GO:0003964 RNA-directed DNA polymerase activity 1/2792 13/18639 0.0769230769230769 0.513527661450298 0.8788014325985 0.999999999999985 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/2792 13/18639 0.0769230769230769 0.513527661450298 0.8788014325985 0.999999999999985 GO:0030955 potassium ion binding 1/2792 13/18639 0.0769230769230769 0.513527661450298 0.8788014325985 0.999999999999985 GO:0032396 inhibitory MHC class I receptor activity 1/2792 13/18639 0.0769230769230769 0.513527661450298 0.8788014325985 0.999999999999985 GO:0039706 co-receptor binding 1/2792 13/18639 0.0769230769230769 0.513527661450298 0.8788014325985 0.999999999999985 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/2792 13/18639 0.0769230769230769 0.513527661450298 0.8788014325985 0.999999999999985 GO:0045159 myosin II binding 1/2792 13/18639 0.0769230769230769 0.513527661450298 0.8788014325985 0.999999999999985 GO:0071837 HMG box domain binding 1/2792 13/18639 0.0769230769230769 0.513527661450298 0.8788014325985 0.999999999999985 GO:0004602 glutathione peroxidase activity 2/2792 23/18639 0.0869565217391304 0.580509530335119 0.879220949230624 0.999999999999985 GO:0031681 G-protein beta-subunit binding 2/2792 23/18639 0.0869565217391304 0.580509530335119 0.879220949230624 0.999999999999985 GO:0099186 structural constituent of postsynapse 2/2792 23/18639 0.0869565217391304 0.580509530335119 0.879220949230624 0.999999999999985 GO:0140103 catalytic activity, acting on a glycoprotein 2/2792 23/18639 0.0869565217391304 0.580509530335119 0.879220949230624 0.999999999999985 GO:0001530 lipopolysaccharide binding 4/2792 41/18639 0.0975609756097561 0.651303375497938 0.881644133840428 0.999999999999985 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/2792 41/18639 0.0975609756097561 0.651303375497938 0.881644133840428 0.999999999999985 GO:0017080 sodium channel regulator activity 4/2792 41/18639 0.0975609756097561 0.651303375497938 0.881644133840428 0.999999999999985 GO:0140318 protein transporter activity 4/2792 41/18639 0.0975609756097561 0.651303375497938 0.881644133840428 0.999999999999985 GO:0003678 DNA helicase activity 8/2792 74/18639 0.108108108108108 0.721714551227445 0.882772788920409 0.999999999999985 GO:0017116 single-stranded DNA helicase activity 6/2792 58/18639 0.103448275862069 0.690606165398676 0.884477204065931 0.999999999999985 GO:0004725 protein tyrosine phosphatase activity 11/2792 98/18639 0.112244897959184 0.749331179463189 0.885622476525179 0.999999999999985 GO:0008013 beta-catenin binding 12/2792 106/18639 0.113207547169811 0.755757690436287 0.887294243328233 0.999999999999985 GO:0048020 CCR chemokine receptor binding 5/2792 50/18639 0.1 0.667585959885387 0.887476614546403 0.999999999999985 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 14/2792 122/18639 0.114754098360656 0.766082249048805 0.891184853430493 0.999999999999985 GO:0030165 PDZ domain binding 9/2792 83/18639 0.108433734939759 0.723888390237166 0.89146955040182 0.999999999999985 GO:0008194 UDP-glycosyltransferase activity 17/2792 145/18639 0.117241379310345 0.782686987451833 0.891689075165517 0.999999999999985 GO:0015295 solute:proton symporter activity 2/2792 24/18639 0.0833333333333333 0.556321633237822 0.893748614419466 0.999999999999985 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/2792 24/18639 0.0833333333333333 0.556321633237822 0.893748614419466 0.999999999999985 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/2792 24/18639 0.0833333333333333 0.556321633237822 0.893748614419466 0.999999999999985 GO:0004879 nuclear receptor activity 6/2792 59/18639 0.101694915254237 0.678900976154631 0.893996088583813 0.999999999999985 GO:0008174 mRNA methyltransferase activity 1/2792 14/18639 0.0714285714285714 0.476847114203848 0.89696885449182 0.999999999999985 GO:0008191 metalloendopeptidase inhibitor activity 1/2792 14/18639 0.0714285714285714 0.476847114203848 0.89696885449182 0.999999999999985 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/2792 14/18639 0.0714285714285714 0.476847114203848 0.89696885449182 0.999999999999985 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/2792 14/18639 0.0714285714285714 0.476847114203848 0.89696885449182 0.999999999999985 GO:0032036 myosin heavy chain binding 1/2792 14/18639 0.0714285714285714 0.476847114203848 0.89696885449182 0.999999999999985 GO:0042043 neurexin family protein binding 1/2792 14/18639 0.0714285714285714 0.476847114203848 0.89696885449182 0.999999999999985 GO:0042813 Wnt receptor activity 1/2792 14/18639 0.0714285714285714 0.476847114203848 0.89696885449182 0.999999999999985 GO:0061783 peptidoglycan muralytic activity 1/2792 14/18639 0.0714285714285714 0.476847114203848 0.89696885449182 0.999999999999985 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/2792 14/18639 0.0714285714285714 0.476847114203848 0.89696885449182 0.999999999999985 GO:1901474 azole transmembrane transporter activity 1/2792 14/18639 0.0714285714285714 0.476847114203848 0.89696885449182 0.999999999999985 GO:1901612 cardiolipin binding 1/2792 14/18639 0.0714285714285714 0.476847114203848 0.89696885449182 0.999999999999985 GO:0016597 amino acid binding 5/2792 51/18639 0.0980392156862745 0.65449603910332 0.897423090326625 0.999999999999985 GO:0003777 microtubule motor activity 7/2792 68/18639 0.102941176470588 0.687220841058486 0.900633830716508 0.999999999999985 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 15/2792 132/18639 0.113636363636364 0.758620408960667 0.905507791689126 0.999999999999985 GO:0001848 complement binding 2/2792 25/18639 0.08 0.534068767908309 0.906635854113313 0.999999999999985 GO:0003707 nuclear steroid receptor activity 2/2792 25/18639 0.08 0.534068767908309 0.906635854113313 0.999999999999985 GO:0015662 P-type ion transporter activity 2/2792 25/18639 0.08 0.534068767908309 0.906635854113313 0.999999999999985 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/2792 25/18639 0.08 0.534068767908309 0.906635854113313 0.999999999999985 GO:0140358 P-type transmembrane transporter activity 2/2792 25/18639 0.08 0.534068767908309 0.906635854113313 0.999999999999985 GO:0004620 phospholipase activity 12/2792 109/18639 0.110091743119266 0.734957020057307 0.907626909845485 0.999999999999985 GO:0022804 active transmembrane transporter activity 59/2792 457/18639 0.12910284463895 0.861872464622272 0.908814105500508 0.999999999999985 GO:0004129 cytochrome-c oxidase activity 1/2792 15/18639 0.0666666666666667 0.445057306590258 0.912413845539275 0.999999999999985 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/2792 15/18639 0.0666666666666667 0.445057306590258 0.912413845539275 0.999999999999985 GO:0004953 icosanoid receptor activity 1/2792 15/18639 0.0666666666666667 0.445057306590258 0.912413845539275 0.999999999999985 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/2792 15/18639 0.0666666666666667 0.445057306590258 0.912413845539275 0.999999999999985 GO:0005523 tropomyosin binding 1/2792 15/18639 0.0666666666666667 0.445057306590258 0.912413845539275 0.999999999999985 GO:0008020 G protein-coupled photoreceptor activity 1/2792 15/18639 0.0666666666666667 0.445057306590258 0.912413845539275 0.999999999999985 GO:0008242 omega peptidase activity 1/2792 15/18639 0.0666666666666667 0.445057306590258 0.912413845539275 0.999999999999985 GO:0010181 FMN binding 1/2792 15/18639 0.0666666666666667 0.445057306590258 0.912413845539275 0.999999999999985 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/2792 15/18639 0.0666666666666667 0.445057306590258 0.912413845539275 0.999999999999985 GO:0016846 carbon-sulfur lyase activity 1/2792 15/18639 0.0666666666666667 0.445057306590258 0.912413845539275 0.999999999999985 GO:0033130 acetylcholine receptor binding 1/2792 15/18639 0.0666666666666667 0.445057306590258 0.912413845539275 0.999999999999985 GO:0016229 steroid dehydrogenase activity 3/2792 35/18639 0.0857142857142857 0.572216537044617 0.912663597272917 0.999999999999985 GO:0008238 exopeptidase activity 11/2792 102/18639 0.107843137254902 0.719945643013652 0.913189463424186 0.999999999999985 GO:0005544 calcium-dependent phospholipid binding 5/2792 53/18639 0.0943396226415094 0.629798075363572 0.915046785691066 0.999999999999985 GO:0016782 transferase activity, transferring sulphur-containing groups 7/2792 70/18639 0.1 0.667585959885387 0.915893403167066 0.999999999999985 GO:0004435 phosphatidylinositol phospholipase C activity 2/2792 26/18639 0.0769230769230769 0.513527661450298 0.918047945422018 0.999999999999985 GO:0019865 immunoglobulin binding 2/2792 26/18639 0.0769230769230769 0.513527661450298 0.918047945422018 0.999999999999985 GO:0050750 low-density lipoprotein particle receptor binding 2/2792 26/18639 0.0769230769230769 0.513527661450298 0.918047945422018 0.999999999999985 GO:0019842 vitamin binding 17/2792 150/18639 0.113333333333333 0.756597421203438 0.919129015990069 0.999999999999985 GO:0008081 phosphoric diester hydrolase activity 9/2792 87/18639 0.103448275862069 0.690606165398676 0.919735949887073 0.999999999999985 GO:0051539 4 iron, 4 sulfur cluster binding 4/2792 45/18639 0.0888888888888889 0.593409742120344 0.921224149647375 0.999999999999985 GO:0015297 antiporter activity 15/2792 135/18639 0.111111111111111 0.74176217765043 0.921644768651329 0.999999999999985 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/2792 36/18639 0.0833333333333333 0.556321633237822 0.922105161772791 0.999999999999985 GO:0140299 molecular sensor activity 7/2792 71/18639 0.0985915492957746 0.658183340732071 0.922733338803811 0.999999999999985 GO:0005024 transforming growth factor beta receptor activity 1/2792 16/18639 0.0625 0.417241224928367 0.925544244124667 0.999999999999985 GO:0008296 3'-5'-DNA exonuclease activity 1/2792 16/18639 0.0625 0.417241224928367 0.925544244124667 0.999999999999985 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/2792 16/18639 0.0625 0.417241224928367 0.925544244124667 0.999999999999985 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/2792 16/18639 0.0625 0.417241224928367 0.925544244124667 0.999999999999985 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/2792 16/18639 0.0625 0.417241224928367 0.925544244124667 0.999999999999985 GO:0004364 glutathione transferase activity 2/2792 27/18639 0.0740740740740741 0.49450811843362 0.928137477555944 0.999999999999985 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 4/2792 46/18639 0.0869565217391304 0.580509530335119 0.929050612834873 0.999999999999985 GO:0043394 proteoglycan binding 3/2792 37/18639 0.0810810810810811 0.541285913420584 0.930603349029174 0.999999999999985 GO:0005516 calmodulin binding 24/2792 207/18639 0.115942028985507 0.774012707113492 0.933292769768711 0.999999999999985 GO:0016298 lipase activity 14/2792 130/18639 0.107692307692308 0.718938726030417 0.93497222922951 0.999999999999985 GO:0015293 symporter activity 16/2792 146/18639 0.10958904109589 0.731601051929191 0.935985806651684 0.999999999999985 GO:0005504 fatty acid binding 4/2792 47/18639 0.0851063829787234 0.568158263732244 0.936167661800795 0.999999999999985 GO:0004550 nucleoside diphosphate kinase activity 1/2792 17/18639 0.0588235294117647 0.392697623461992 0.93670681032796 0.999999999999985 GO:0008569 minus-end-directed microtubule motor activity 1/2792 17/18639 0.0588235294117647 0.392697623461992 0.93670681032796 0.999999999999985 GO:0009881 photoreceptor activity 1/2792 17/18639 0.0588235294117647 0.392697623461992 0.93670681032796 0.999999999999985 GO:0045125 bioactive lipid receptor activity 1/2792 17/18639 0.0588235294117647 0.392697623461992 0.93670681032796 0.999999999999985 GO:0038024 cargo receptor activity 6/2792 65/18639 0.0923076923076923 0.616233193740357 0.938100253310597 0.999999999999985 GO:0005501 retinoid binding 3/2792 38/18639 0.0789473684210526 0.527041547277937 0.938240205124757 0.999999999999985 GO:0019840 isoprenoid binding 3/2792 38/18639 0.0789473684210526 0.527041547277937 0.938240205124757 0.999999999999985 GO:0033218 amide binding 29/2792 247/18639 0.117408906882591 0.783805378003086 0.940241958310252 0.999999999999985 GO:0001540 amyloid-beta binding 8/2792 83/18639 0.0963855421686747 0.643456346877481 0.943126395029143 0.999999999999985 GO:0004175 endopeptidase activity 50/2792 405/18639 0.123456790123457 0.824180197389366 0.94496405123628 0.999999999999985 GO:0061134 peptidase regulator activity 26/2792 226/18639 0.115044247787611 0.768019245885843 0.945511905367821 0.999999999999985 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/2792 18/18639 0.0555555555555556 0.370881088825215 0.946196370287381 0.999999999999985 GO:0034185 apolipoprotein binding 1/2792 18/18639 0.0555555555555556 0.370881088825215 0.946196370287381 0.999999999999985 GO:0099602 neurotransmitter receptor regulator activity 1/2792 18/18639 0.0555555555555556 0.370881088825215 0.946196370287381 0.999999999999985 GO:0008509 monoatomic anion transmembrane transporter activity 16/2792 149/18639 0.10738255033557 0.716870829407127 0.947276150892964 0.999999999999985 GO:0050840 extracellular matrix binding 6/2792 67/18639 0.0895522388059701 0.59783817303169 0.948662563037134 0.999999999999985 GO:0071855 neuropeptide receptor binding 3/2792 40/18639 0.075 0.50068946991404 0.951232478434729 0.999999999999985 GO:0001968 fibronectin binding 2/2792 30/18639 0.0666666666666667 0.445057306590258 0.95180993428035 0.999999999999985 GO:0048019 receptor antagonist activity 2/2792 30/18639 0.0666666666666667 0.445057306590258 0.95180993428035 0.999999999999985 GO:0098918 structural constituent of synapse 2/2792 30/18639 0.0666666666666667 0.445057306590258 0.95180993428035 0.999999999999985 GO:0004222 metalloendopeptidase activity 11/2792 110/18639 0.1 0.667585959885387 0.951817340583461 0.999999999999985 GO:0005017 platelet-derived growth factor receptor activity 4/2792 50/18639 0.08 0.534068767908309 0.953794777487061 0.999999999999985 GO:0005019 platelet-derived growth factor beta-receptor activity 4/2792 50/18639 0.08 0.534068767908309 0.953794777487061 0.999999999999985 GO:0003756 protein disulfide isomerase activity 1/2792 19/18639 0.0526315789473684 0.351361031518625 0.954263591927338 0.999999999999985 GO:0008574 plus-end-directed microtubule motor activity 1/2792 19/18639 0.0526315789473684 0.351361031518625 0.954263591927338 0.999999999999985 GO:0015245 fatty acid transmembrane transporter activity 1/2792 19/18639 0.0526315789473684 0.351361031518625 0.954263591927338 0.999999999999985 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/2792 19/18639 0.0526315789473684 0.351361031518625 0.954263591927338 0.999999999999985 GO:0016918 retinal binding 1/2792 19/18639 0.0526315789473684 0.351361031518625 0.954263591927338 0.999999999999985 GO:0022840 leak channel activity 1/2792 19/18639 0.0526315789473684 0.351361031518625 0.954263591927338 0.999999999999985 GO:0022842 narrow pore channel activity 1/2792 19/18639 0.0526315789473684 0.351361031518625 0.954263591927338 0.999999999999985 GO:0034987 immunoglobulin receptor binding 1/2792 19/18639 0.0526315789473684 0.351361031518625 0.954263591927338 0.999999999999985 GO:0043395 heparan sulfate proteoglycan binding 1/2792 19/18639 0.0526315789473684 0.351361031518625 0.954263591927338 0.999999999999985 GO:0046527 glucosyltransferase activity 1/2792 19/18639 0.0526315789473684 0.351361031518625 0.954263591927338 0.999999999999985 GO:1902936 phosphatidylinositol bisphosphate binding 11/2792 111/18639 0.0990990990990991 0.661571671958491 0.9553821740563 0.999999999999985 GO:0004812 aminoacyl-tRNA ligase activity 3/2792 41/18639 0.0731707317073171 0.488477531623454 0.956726295113227 0.999999999999985 GO:0016875 ligase activity, forming carbon-oxygen bonds 3/2792 41/18639 0.0731707317073171 0.488477531623454 0.956726295113227 0.999999999999985 GO:0016247 channel regulator activity 18/2792 168/18639 0.107142857142857 0.715270671305772 0.957089541711794 0.999999999999985 GO:0004714 transmembrane receptor protein tyrosine kinase activity 5/2792 60/18639 0.0833333333333333 0.556321633237822 0.957488985124898 0.999999999999985 GO:0017147 Wnt-protein binding 2/2792 31/18639 0.0645161290322581 0.430700619280895 0.957889430440888 0.999999999999985 GO:0070325 lipoprotein particle receptor binding 2/2792 31/18639 0.0645161290322581 0.430700619280895 0.957889430440888 0.999999999999985 GO:0008514 organic anion transmembrane transporter activity 31/2792 269/18639 0.115241635687732 0.769336979793568 0.957929565733525 0.999999999999985 GO:0005010 insulin-like growth factor receptor activity 4/2792 51/18639 0.0784313725490196 0.523596831282656 0.958592367883694 0.999999999999985 GO:0005030 neurotrophin receptor activity 4/2792 51/18639 0.0784313725490196 0.523596831282656 0.958592367883694 0.999999999999985 GO:0005178 integrin binding 17/2792 161/18639 0.105590062111801 0.704904429692644 0.959651004469214 0.999999999999985 GO:0005326 neurotransmitter transmembrane transporter activity 1/2792 20/18639 0.05 0.333792979942693 0.961121596832755 0.999999999999985 GO:0010851 cyclase regulator activity 1/2792 20/18639 0.05 0.333792979942693 0.961121596832755 0.999999999999985 GO:0015464 acetylcholine receptor activity 1/2792 20/18639 0.05 0.333792979942693 0.961121596832755 0.999999999999985 GO:0030627 pre-mRNA 5'-splice site binding 1/2792 20/18639 0.05 0.333792979942693 0.961121596832755 0.999999999999985 GO:0031418 L-ascorbic acid binding 1/2792 20/18639 0.05 0.333792979942693 0.961121596832755 0.999999999999985 GO:0042288 MHC class I protein binding 1/2792 20/18639 0.05 0.333792979942693 0.961121596832755 0.999999999999985 GO:0008307 structural constituent of muscle 3/2792 42/18639 0.0714285714285714 0.476847114203848 0.96163573073311 0.999999999999985 GO:0141108 transporter regulator activity 18/2792 170/18639 0.105882352941176 0.706855722231586 0.962313822129561 0.999999999999985 GO:0036122 BMP binding 1/2792 21/18639 0.0476190476190476 0.317898076135898 0.96695158241968 0.999999999999985 GO:0051428 peptide hormone receptor binding 1/2792 21/18639 0.0476190476190476 0.317898076135898 0.96695158241968 0.999999999999985 GO:0061891 calcium ion sensor activity 1/2792 21/18639 0.0476190476190476 0.317898076135898 0.96695158241968 0.999999999999985 GO:0046943 carboxylic acid transmembrane transporter activity 20/2792 188/18639 0.106382978723404 0.710197829665305 0.967129414895692 0.999999999999985 GO:0001664 G protein-coupled receptor binding 34/2792 297/18639 0.114478114478114 0.764239819397413 0.967780797753084 0.999999999999985 GO:0005518 collagen binding 6/2792 72/18639 0.0833333333333333 0.556321633237822 0.968329632010268 0.999999999999985 GO:0005342 organic acid transmembrane transporter activity 20/2792 189/18639 0.105820105820106 0.706440169190885 0.969171307504639 0.999999999999985 GO:0030547 signaling receptor inhibitor activity 3/2792 44/18639 0.0681818181818182 0.4551722453764 0.969923888887643 0.999999999999985 GO:0015294 solute:monoatomic cation symporter activity 11/2792 116/18639 0.0948275862068965 0.633055651615453 0.969928104114157 0.999999999999985 GO:0072341 modified amino acid binding 8/2792 91/18639 0.0879120879120879 0.586888755943197 0.97176080282126 0.999999999999985 GO:0005243 gap junction channel activity 1/2792 22/18639 0.0454545454545455 0.303448163584267 0.97190760250155 0.999999999999985 GO:0033691 sialic acid binding 1/2792 22/18639 0.0454545454545455 0.303448163584267 0.97190760250155 0.999999999999985 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/2792 34/18639 0.0588235294117647 0.392697623461992 0.972023336919991 0.999999999999985 GO:0008237 metallopeptidase activity 19/2792 184/18639 0.103260869565217 0.689355067272954 0.974680850248905 0.999999999999985 GO:0099106 ion channel regulator activity 16/2792 160/18639 0.1 0.667585959885387 0.975237072425736 0.999999999999985 GO:0005343 organic acid:sodium symporter activity 2/2792 35/18639 0.0571428571428571 0.381477691363078 0.975620896898602 0.999999999999985 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/2792 23/18639 0.0434782608695652 0.290254765167559 0.976120632195683 0.999999999999985 GO:0005212 structural constituent of eye lens 1/2792 23/18639 0.0434782608695652 0.290254765167559 0.976120632195683 0.999999999999985 GO:0005283 amino acid:sodium symporter activity 1/2792 23/18639 0.0434782608695652 0.290254765167559 0.976120632195683 0.999999999999985 GO:0016849 phosphorus-oxygen lyase activity 1/2792 23/18639 0.0434782608695652 0.290254765167559 0.976120632195683 0.999999999999985 GO:0015171 amino acid transmembrane transporter activity 9/2792 102/18639 0.0882352941176471 0.589046435192988 0.97691987814242 0.999999999999985 GO:0004190 aspartic-type endopeptidase activity 2/2792 36/18639 0.0555555555555556 0.370881088825215 0.978768881317767 0.999999999999985 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 2/2792 36/18639 0.0555555555555556 0.370881088825215 0.978768881317767 0.999999999999985 GO:0005506 iron ion binding 15/2792 154/18639 0.0974025974025974 0.650246064823429 0.978962149702573 0.999999999999985 GO:0016500 protein-hormone receptor activity 5/2792 67/18639 0.0746268656716418 0.498198477526408 0.979635500175877 0.999999999999985 GO:0004806 triacylglycerol lipase activity 1/2792 24/18639 0.0416666666666667 0.278160816618911 0.979702024272909 0.999999999999985 GO:0005540 hyaluronic acid binding 1/2792 24/18639 0.0416666666666667 0.278160816618911 0.979702024272909 0.999999999999985 GO:0050431 transforming growth factor beta binding 1/2792 24/18639 0.0416666666666667 0.278160816618911 0.979702024272909 0.999999999999985 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 7/2792 86/18639 0.0813953488372093 0.543383920836943 0.98046881206256 0.999999999999985 GO:0030280 structural constituent of skin epidermis 2/2792 37/18639 0.0540540540540541 0.360857275613723 0.981521197448544 0.999999999999985 GO:0070001 aspartic-type peptidase activity 2/2792 37/18639 0.0540540540540541 0.360857275613723 0.981521197448544 0.999999999999985 GO:0016758 hexosyltransferase activity 20/2792 197/18639 0.101522842639594 0.677752243538464 0.981856795690175 0.999999999999985 GO:0019199 transmembrane receptor protein kinase activity 6/2792 78/18639 0.0769230769230769 0.513527661450298 0.982718394214803 0.999999999999985 GO:0000030 mannosyltransferase activity 1/2792 25/18639 0.04 0.267034383954155 0.982746448029559 0.999999999999985 GO:0005251 delayed rectifier potassium channel activity 1/2792 25/18639 0.04 0.267034383954155 0.982746448029559 0.999999999999985 GO:0003730 mRNA 3'-UTR binding 28/2792 262/18639 0.106870229007634 0.713450644152322 0.983112068119498 0.999999999999985 GO:0001786 phosphatidylserine binding 4/2792 59/18639 0.0677966101694915 0.452600650769754 0.983286037254589 0.999999999999985 GO:0005004 GPI-linked ephrin receptor activity 3/2792 49/18639 0.0612244897959184 0.408726097889012 0.983852670427193 0.999999999999985 GO:0005008 hepatocyte growth factor receptor activity 3/2792 49/18639 0.0612244897959184 0.408726097889012 0.983852670427193 0.999999999999985 GO:0005009 insulin receptor activity 3/2792 49/18639 0.0612244897959184 0.408726097889012 0.983852670427193 0.999999999999985 GO:0005011 macrophage colony-stimulating factor receptor activity 3/2792 49/18639 0.0612244897959184 0.408726097889012 0.983852670427193 0.999999999999985 GO:0005018 platelet-derived growth factor alpha-receptor activity 3/2792 49/18639 0.0612244897959184 0.408726097889012 0.983852670427193 0.999999999999985 GO:0005020 stem cell factor receptor activity 3/2792 49/18639 0.0612244897959184 0.408726097889012 0.983852670427193 0.999999999999985 GO:0008288 boss receptor activity 3/2792 49/18639 0.0612244897959184 0.408726097889012 0.983852670427193 0.999999999999985 GO:0036332 placental growth factor receptor activity 3/2792 49/18639 0.0612244897959184 0.408726097889012 0.983852670427193 0.999999999999985 GO:0038062 protein tyrosine kinase collagen receptor activity 3/2792 49/18639 0.0612244897959184 0.408726097889012 0.983852670427193 0.999999999999985 GO:0060175 brain-derived neurotrophic factor receptor activity 3/2792 49/18639 0.0612244897959184 0.408726097889012 0.983852670427193 0.999999999999985 GO:0005109 frizzled binding 2/2792 38/18639 0.0526315789473684 0.351361031518625 0.983925697022087 0.999999999999985 GO:0033293 monocarboxylic acid binding 6/2792 79/18639 0.0759493670886076 0.507027311305357 0.984417322799453 0.999999999999985 GO:0015291 secondary active transmembrane transporter activity 31/2792 287/18639 0.10801393728223 0.721085880015575 0.984466803278592 0.999999999999985 GO:0005227 calcium-activated cation channel activity 1/2792 26/18639 0.0384615384615385 0.256763830725149 0.985334388133861 0.999999999999985 GO:0030507 spectrin binding 1/2792 26/18639 0.0384615384615385 0.256763830725149 0.985334388133861 0.999999999999985 GO:0070006 metalloaminopeptidase activity 1/2792 26/18639 0.0384615384615385 0.256763830725149 0.985334388133861 0.999999999999985 GO:0005006 epidermal growth factor receptor activity 3/2792 50/18639 0.06 0.400551575931232 0.985771259338265 0.999999999999985 GO:0005007 fibroblast growth factor receptor activity 3/2792 50/18639 0.06 0.400551575931232 0.985771259338265 0.999999999999985 GO:0005021 vascular endothelial growth factor receptor activity 3/2792 51/18639 0.0588235294117647 0.392697623461992 0.987469940054176 0.999999999999985 GO:0005044 scavenger receptor activity 1/2792 27/18639 0.037037037037037 0.24725405921681 0.987534269309935 0.999999999999985 GO:0008395 steroid hydroxylase activity 1/2792 27/18639 0.037037037037037 0.24725405921681 0.987534269309935 0.999999999999985 GO:0019955 cytokine binding 13/2792 144/18639 0.0902777777777778 0.602681769340974 0.987706355875673 0.999999999999985 GO:0042287 MHC protein binding 2/2792 41/18639 0.0487804878048781 0.325651687748969 0.989452346603761 0.999999999999985 GO:0005003 ephrin receptor activity 3/2792 53/18639 0.0566037735849057 0.377878845218143 0.990301015433635 0.999999999999985 GO:0005005 transmembrane-ephrin receptor activity 3/2792 53/18639 0.0566037735849057 0.377878845218143 0.990301015433635 0.999999999999985 GO:0038064 collagen receptor activity 3/2792 53/18639 0.0566037735849057 0.377878845218143 0.990301015433635 0.999999999999985 GO:0005253 monoatomic anion channel activity 8/2792 103/18639 0.0776699029126214 0.518513366901271 0.990920291280184 0.999999999999985 GO:0003785 actin monomer binding 1/2792 29/18639 0.0344827586206897 0.230202055132892 0.990993822701373 0.999999999999985 GO:0004181 metallocarboxypeptidase activity 1/2792 29/18639 0.0344827586206897 0.230202055132892 0.990993822701373 0.999999999999985 GO:0005416 amino acid:monoatomic cation symporter activity 1/2792 29/18639 0.0344827586206897 0.230202055132892 0.990993822701373 0.999999999999985 GO:0015103 inorganic anion transmembrane transporter activity 15/2792 165/18639 0.0909090909090909 0.606896327168533 0.991025712420247 0.999999999999985 GO:0042562 hormone binding 7/2792 94/18639 0.074468085106383 0.497138480765714 0.991229054643037 0.999999999999985 GO:0061135 endopeptidase regulator activity 17/2792 184/18639 0.0923913043478261 0.616791375981064 0.99233431738768 0.999999999999985 GO:0022839 monoatomic ion-gated channel activity 1/2792 30/18639 0.0333333333333333 0.222528653295129 0.992344991267615 0.999999999999985 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/2792 44/18639 0.0454545454545455 0.303448163584267 0.993108006941222 0.999999999999985 GO:0004497 monooxygenase activity 8/2792 106/18639 0.0754716981132075 0.503838460290858 0.993256754566653 0.999999999999985 GO:0005184 neuropeptide hormone activity 1/2792 31/18639 0.032258064516129 0.215350309640447 0.993493509961839 0.999999999999985 GO:0160041 neuropeptide activity 1/2792 32/18639 0.03125 0.208620612464183 0.994469763196284 0.999999999999985 GO:0019838 growth factor binding 11/2792 136/18639 0.0808823529411765 0.539959232260239 0.994666752249576 0.999999999999985 GO:0015370 solute:sodium symporter activity 5/2792 79/18639 0.0632911392405063 0.422522759421131 0.994682710652546 0.999999999999985 GO:0019956 chemokine binding 1/2792 33/18639 0.0303030303030303 0.202298775722845 0.995299581068911 0.999999999999985 GO:0042923 neuropeptide binding 1/2792 33/18639 0.0303030303030303 0.202298775722845 0.995299581068911 0.999999999999985 GO:0099095 ligand-gated monoatomic anion channel activity 2/2792 47/18639 0.0425531914893617 0.284079131866122 0.99551347573509 0.999999999999985 GO:0015085 calcium ion transmembrane transporter activity 12/2792 147/18639 0.0816326530612245 0.544968130518683 0.995553071754757 0.999999999999985 GO:1901681 sulfur compound binding 27/2792 275/18639 0.0981818181818182 0.655448033342016 0.995667170653288 0.999999999999985 GO:0003823 antigen binding 15/2792 174/18639 0.0862068965517241 0.57550513783223 0.995719226270878 0.999999999999985 GO:0008188 neuropeptide receptor activity 2/2792 48/18639 0.0416666666666667 0.278160816618911 0.996114602175208 0.999999999999985 GO:0015108 chloride transmembrane transporter activity 9/2792 121/18639 0.0743801652892562 0.496551540410618 0.996149812766028 0.999999999999985 GO:0005262 calcium channel activity 10/2792 131/18639 0.0763358778625954 0.509607602965944 0.996393447364438 0.999999999999985 GO:0020037 heme binding 11/2792 142/18639 0.0774647887323944 0.517144053432342 0.996953844323042 0.999999999999985 GO:0046906 tetrapyrrole binding 12/2792 152/18639 0.0789473684210526 0.527041547277937 0.997185856022751 0.999999999999985 GO:0004867 serine-type endopeptidase inhibitor activity 6/2792 95/18639 0.0631578947368421 0.42163323782235 0.997263280424892 0.999999999999985 GO:0048029 monosaccharide binding 4/2792 74/18639 0.0540540540540541 0.360857275613723 0.997281913236696 0.999999999999985 GO:0005125 cytokine activity 21/2792 234/18639 0.0897435897435897 0.599115605025347 0.997792307036749 0.999999999999985 GO:0008235 metalloexopeptidase activity 3/2792 66/18639 0.0454545454545455 0.303448163584267 0.998255454758056 0.999999999999985 GO:0031406 carboxylic acid binding 15/2792 187/18639 0.0802139037433155 0.535496759266353 0.9986181115108 0.999999999999985 GO:0140828 metal cation:monoatomic cation antiporter activity 1/2792 41/18639 0.024390243902439 0.162825843874485 0.998720233059554 0.999999999999985 GO:0170055 lipid transmembrane transporter activity 2/2792 56/18639 0.0357142857142857 0.238423557101924 0.998785246112481 0.999999999999985 GO:0043177 organic acid binding 15/2792 189/18639 0.0793650793650794 0.529830126893164 0.998845650868377 0.999999999999985 GO:0042056 chemoattractant activity 1/2792 42/18639 0.0238095238095238 0.158949038067949 0.99891235636839 0.999999999999985 GO:0008201 heparin binding 13/2792 172/18639 0.0755813953488372 0.504570783634304 0.998978608534072 0.999999999999985 GO:0005254 chloride channel activity 4/2792 83/18639 0.0481927710843374 0.321728173438741 0.999134407375598 0.999999999999985 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/2792 46/18639 0.0217391304347826 0.14512738258378 0.999432627473848 0.999999999999985 GO:0008083 growth factor activity 11/2792 162/18639 0.0679012345679012 0.453299108564152 0.999579520491202 0.999999999999985 GO:0005272 sodium channel activity 1/2792 51/18639 0.0196078431372549 0.130899207820664 0.999748520527419 0.999999999999985 GO:0017046 peptide hormone binding 1/2792 53/18639 0.0188679245283019 0.125959615072714 0.999818395195724 0.999999999999985 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/2792 53/18639 0.0188679245283019 0.125959615072714 0.999818395195724 0.999999999999985 GO:0004866 endopeptidase inhibitor activity 10/2792 161/18639 0.062111801242236 0.414649664525085 0.999836272576695 0.999999999999985 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/2792 56/18639 0.0178571428571429 0.119211778550962 0.999888561940052 0.999999999999985 GO:0030246 carbohydrate binding 22/2792 280/18639 0.0785714285714286 0.524531825624233 0.999902034444222 0.999999999999985 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/2792 73/18639 0.0273972602739726 0.182900262982298 0.999902700391721 0.999999999999985 GO:0099094 ligand-gated monoatomic cation channel activity 7/2792 136/18639 0.0514705882352941 0.343610420529243 0.999922366799793 0.999999999999985 GO:0005201 extracellular matrix structural constituent 10/2792 168/18639 0.0595238095238095 0.397372595169873 0.999924117182595 0.999999999999985 GO:0030414 peptidase inhibitor activity 10/2792 169/18639 0.0591715976331361 0.39502127803869 0.999932097751405 0.999999999999985 GO:0015026 coreceptor activity 1/2792 61/18639 0.0163934426229508 0.109440321292686 0.999950630213698 0.999999999999985 GO:0008236 serine-type peptidase activity 12/2792 194/18639 0.0618556701030928 0.41293976900127 0.999959023282874 0.999999999999985 GO:0022824 transmitter-gated monoatomic ion channel activity 1/2792 63/18639 0.0158730158730159 0.105966025378633 0.99996435460822 0.999999999999985 GO:0022835 transmitter-gated channel activity 1/2792 63/18639 0.0158730158730159 0.105966025378633 0.99996435460822 0.999999999999985 GO:0005179 hormone activity 6/2792 132/18639 0.0454545454545455 0.303448163584267 0.999968391249113 0.999999999999985 GO:0004252 serine-type endopeptidase activity 10/2792 176/18639 0.0568181818181818 0.379310204480333 0.999969066172197 0.999999999999985 GO:0017171 serine hydrolase activity 12/2792 198/18639 0.0606060606060606 0.404597551445689 0.999973422111077 0.999999999999985 GO:0008528 G protein-coupled peptide receptor activity 5/2792 122/18639 0.040983606557377 0.273600803231716 0.99997503947755 0.999999999999985 GO:0098960 postsynaptic neurotransmitter receptor activity 1/2792 69/18639 0.0144927536231884 0.0967515883891865 0.999986586856671 0.999999999999985 GO:0001653 peptide receptor activity 5/2792 128/18639 0.0390625 0.260775765580229 0.999988725866673 0.999999999999985 GO:0015081 sodium ion transmembrane transporter activity 8/2792 164/18639 0.0487804878048781 0.325651687748969 0.999990008735441 0.999999999999985 GO:0030594 neurotransmitter receptor activity 2/2792 97/18639 0.0206185567010309 0.13764658966709 0.999997461272614 0.999999999999985 GO:0022834 ligand-gated channel activity 9/2792 188/18639 0.0478723404255319 0.319589023349387 0.999997898402806 0.999999999999985 GO:0005539 glycosaminoglycan binding 14/2792 242/18639 0.0578512396694215 0.386206753652703 0.999997977963181 0.999999999999985 GO:0015079 potassium ion transmembrane transporter activity 6/2792 160/18639 0.0375 0.25034473495702 0.999999172446705 0.999999999999985 GO:0015276 ligand-gated monoatomic ion channel activity 8/2792 186/18639 0.043010752688172 0.287133746187263 0.999999352537297 0.999999999999985 GO:0005249 voltage-gated potassium channel activity 1/2792 98/18639 0.0102040816326531 0.0681210163148354 0.999999881475023 0.999999999999985 GO:0030527 structural constituent of chromatin 1/2792 98/18639 0.0102040816326531 0.0681210163148354 0.999999881475023 0.999999999999985 GO:0046873 metal ion transmembrane transporter activity 31/2792 450/18639 0.0688888888888889 0.459892550143266 0.999999968763036 0.999999999999985 GO:0005267 potassium channel activity 1/2792 124/18639 0.00806451612903226 0.0538375774101118 0.999999998303419 0.999999999999985 GO:0005244 voltage-gated monoatomic ion channel activity 3/2792 173/18639 0.0173410404624277 0.115766351425212 0.999999999719227 0.999999999999985 GO:0005261 monoatomic cation channel activity 16/2792 341/18639 0.0469208211143695 0.313236814022469 0.999999999747334 0.999999999999985 GO:0022832 voltage-gated channel activity 3/2792 175/18639 0.0171428571428571 0.114443307408923 0.9999999997931 0.999999999999985 GO:0022843 voltage-gated monoatomic cation channel activity 1/2792 143/18639 0.00699300699300699 0.046684332859118 0.999999999924128 0.999999999999985 GO:0045182 translation regulator activity 15/2792 356/18639 0.0421348314606742 0.281286219052832 0.999999999990244 0.999999999999985 GO:0005216 monoatomic ion channel activity 23/2792 448/18639 0.0513392857142857 0.342733863334016 0.999999999993017 0.999999999999985 GO:0022836 gated channel activity 11/2792 318/18639 0.0345911949685535 0.230925960966643 0.999999999997457 0.999999999999985 GO:0030371 translation repressor activity 9/2792 329/18639 0.027355623100304 0.182622299056793 0.999999999999985 0.999999999999985