ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0051020	GTPase binding	106/3063	315/18639	0.336507936507937	2.04772165477356	3.78317933260117e-14	4.17572027066958e-11
GO:0045296	cadherin binding	110/3063	334/18639	0.329341317365269	2.00411126815908	6.43904436494923e-14	4.17572027066958e-11
GO:0031267	small GTPase binding	94/3063	283/18639	0.332155477031802	2.02123602232966	2.47119832883923e-12	1.06838141083483e-09
GO:0030695	GTPase regulator activity	139/3063	489/18639	0.284253578732106	1.72974288409655	1.13953762628539e-11	3.47083159686798e-09
GO:0060589	nucleoside-triphosphatase regulator activity	139/3063	490/18639	0.283673469387755	1.72621279657798	1.33802297489128e-11	3.47083159686798e-09
GO:0015631	tubulin binding	112/3063	385/18639	0.290909090909091	1.77024307719704	2.59121437719538e-10	5.60134174537067e-08
GO:0005543	phospholipid binding	136/3063	497/18639	0.27364185110664	1.66516828690064	3.28613662319555e-10	6.08874171469233e-08
GO:0003779	actin binding	121/3063	443/18639	0.27313769751693	1.66210040614367	3.50929860662811e-09	5.68945036599582e-07
GO:0035091	phosphatidylinositol binding	85/3063	284/18639	0.299295774647887	1.82127781379757	8.6377368757253e-09	1.24479385864619e-06
GO:0005096	GTPase activator activity	80/3063	271/18639	0.29520295202952	1.79637212630696	4.55116954964719e-08	5.9028669058924e-06
GO:0008017	microtubule binding	80/3063	276/18639	0.289855072463768	1.7638291530043	1.07740822493191e-07	1.27036224339699e-05
GO:0046332	SMAD binding	32/3063	79/18639	0.40506329113924	2.46489542394525	2.93168968714152e-07	3.16866793685213e-05
GO:0004812	aminoacyl-tRNA ligase activity	20/3063	41/18639	0.48780487804878	2.96839540383651	1.53378954066471e-06	0.000142094645303009
GO:0016875	ligase activity, forming carbon-oxygen bonds	20/3063	41/18639	0.48780487804878	2.96839540383651	1.53378954066471e-06	0.000142094645303009
GO:0004674	protein serine/threonine kinase activity	109/3063	433/18639	0.251732101616628	1.53184284754565	1.74417542190438e-06	0.000146992929183804
GO:0106310	protein serine kinase activity	94/3063	361/18639	0.260387811634349	1.58451466570442	1.92193091430533e-06	0.000146992929183804
GO:0005085	guanyl-nucleotide exchange factor activity	66/3063	230/18639	0.28695652173913	1.74619086147426	1.9858834879782e-06	0.000146992929183804
GO:0019208	phosphatase regulator activity	40/3063	117/18639	0.341880341880342	2.0804138727743	2.03999439113991e-06	0.000146992929183804
GO:0070064	proline-rich region binding	12/3063	18/18639	0.666666666666667	4.05680705190989	2.65209898423999e-06	0.000171988619127963
GO:0098641	cadherin binding involved in cell-cell adhesion	12/3063	18/18639	0.666666666666667	4.05680705190989	2.65209898423999e-06	0.000171988619127963
GO:0051015	actin filament binding	60/3063	209/18639	0.287081339712919	1.74695040512866	5.59659294164061e-06	0.000345656240252756
GO:0043236	laminin binding	15/3063	29/18639	0.517241379310345	3.14752271268871	1.27481094838791e-05	0.000751559000026874
GO:0019902	phosphatase binding	54/3063	190/18639	0.284210526315789	1.72948090107738	2.19219158640274e-05	0.000997967318148876
GO:0140857	histone H3T45 kinase activity	66/3063	246/18639	0.268292682926829	1.63261747211008	2.2551016868967e-05	0.000997967318148876
GO:0019888	protein phosphatase regulator activity	35/3063	107/18639	0.327102803738318	1.99048944135766	2.56494860757445e-05	0.000997967318148876
GO:0035402	histone H3T11 kinase activity	66/3063	247/18639	0.267206477732794	1.6260076847736	2.59075921815329e-05	0.000997967318148876
GO:0035403	histone H3T6 kinase activity	66/3063	247/18639	0.267206477732794	1.6260076847736	2.59075921815329e-05	0.000997967318148876
GO:0001786	phosphatidylserine binding	23/3063	59/18639	0.389830508474576	2.37220073374392	2.79590564246253e-05	0.000997967318148876
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	65/3063	243/18639	0.267489711934156	1.62773122453175	2.86673471095804e-05	0.000997967318148876
GO:0004679	AMP-activated protein kinase activity	66/3063	248/18639	0.266129032258065	1.61945120217371	2.97206439035632e-05	0.000997967318148876
GO:0019207	kinase regulator activity	74/3063	287/18639	0.257839721254355	1.56900899917072	3.25561372739654e-05	0.000997967318148876
GO:0031994	insulin-like growth factor I binding	9/3063	13/18639	0.692307692307692	4.21283809236796	3.27370141753216e-05	0.000997967318148876
GO:0004676	3-phosphoinositide-dependent protein kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0004711	ribosomal protein S6 kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0035175	histone H3S10 kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0035979	histone H2AXS139 kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0044022	histone H3S28 kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0044023	histone H4S1 kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0044024	histone H2AS1 kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0044025	histone H2BS14 kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0072354	histone H3T3 kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0072371	histone H2AS121 kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0072518	Rho-dependent protein serine/threonine kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0140823	histone H2BS36 kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0140855	histone H3S57 kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0140995	histone H2A kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0140997	histone H4 kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0140998	histone H2B kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:1990244	histone H2AT120 kinase activity	65/3063	245/18639	0.26530612244898	1.61444362269883	3.77026974474132e-05	0.000997967318148876
GO:0140996	histone H3 kinase activity	88/3063	357/18639	0.246498599439776	1.49999588473979	3.88254938552206e-05	0.00100713331060442
GO:0019887	protein kinase regulator activity	67/3063	255/18639	0.262745098039216	1.59885924987037	4.01430859952464e-05	0.00102089377521244
GO:0004677	DNA-dependent protein kinase activity	65/3063	246/18639	0.264227642276423	1.60788084374477	4.31439087048662e-05	0.00107610864596561
GO:0019787	ubiquitin-like protein transferase activity	112/3063	479/18639	0.233820459290188	1.42284673219387	4.43289055612084e-05	0.00108480359458278
GO:0019211	phosphatase activator activity	13/3063	25/18639	0.52	3.16430950048972	4.5334263445882e-05	0.00108886184609831
GO:0141003	histone H2AX kinase activity	87/3063	354/18639	0.245762711864407	1.49551785388204	4.80892158923118e-05	0.00111398359598355
GO:0005520	insulin-like growth factor binding	11/3063	19/18639	0.578947368421053	3.5230166503428	4.80979810139388e-05	0.00111398359598355
GO:0035173	histone kinase activity	88/3063	360/18639	0.244444444444444	1.48749591903363	5.3774544336003e-05	0.00121530631255655
GO:0002162	dystroglycan binding	8/3063	11/18639	0.727272727272727	4.42560769299261	5.43467741929683e-05	0.00121530631255655
GO:0016755	aminoacyltransferase activity	114/3063	496/18639	0.229838709677419	1.39861694733184	8.16835760070522e-05	0.00179012458413666
GO:0019209	kinase activator activity	43/3063	148/18639	0.290540540540541	1.76800037059587	8.28122398212795e-05	0.00179012458413666
GO:1901981	phosphatidylinositol phosphate binding	51/3063	185/18639	0.275675675675676	1.67754453768166	8.69661389577959e-05	0.00184909970866002
GO:0051010	microtubule plus-end binding	11/3063	21/18639	0.523809523809524	3.18749125507206	0.000162732959180758	0.00335023250884829
GO:0072542	protein phosphatase activator activity	11/3063	21/18639	0.523809523809524	3.18749125507206	0.000162732959180758	0.00335023250884829
GO:0005200	structural constituent of cytoskeleton	34/3063	112/18639	0.303571428571429	1.8472960682804	0.000175849131440345	0.00356369255434575
GO:0030295	protein kinase activator activity	40/3063	139/18639	0.287769784172662	1.75113973463736	0.000180231740843636	0.00359631642883379
GO:0015485	cholesterol binding	20/3063	54/18639	0.37037037037037	2.2537816955055	0.000209333368730013	0.00411371786731555
GO:0048156	tau protein binding	17/3063	43/18639	0.395348837209302	2.40578092613261	0.000249111906557487	0.00482236034037404
GO:0031625	ubiquitin protein ligase binding	73/3063	302/18639	0.241721854304636	1.47092838471567	0.000318366829344505	0.0060723790832327
GO:0032934	sterol binding	23/3063	68/18639	0.338235294117647	2.05823298957193	0.000344836138302045	0.0064819198750399
GO:0016874	ligase activity	45/3063	167/18639	0.269461077844311	1.63972740122106	0.000381204748141417	0.00706317940484882
GO:0019903	protein phosphatase binding	40/3063	144/18639	0.277777777777778	1.69033627162912	0.000402966635481164	0.00736123558055027
GO:0005496	steroid binding	32/3063	108/18639	0.296296296296296	1.8030253564044	0.000434705437127846	0.00783073544381689
GO:0004842	ubiquitin-protein transferase activity	101/3063	449/18639	0.224944320712695	1.36883355983151	0.000456122980583075	0.00810399323035956
GO:0019838	growth factor binding	38/3063	136/18639	0.279411764705882	1.70027942616812	0.000489747862319948	0.00857989979554265
GO:0072341	modified amino acid binding	28/3063	91/18639	0.307692307692308	1.87237248549687	0.000496139155486275	0.00857989979554265
GO:0034236	protein kinase A catalytic subunit binding	8/3063	14/18639	0.571428571428571	3.47726318735134	0.000619338255721269	0.010569496285138
GO:0019003	GDP binding	24/3063	75/18639	0.32	1.94726738491675	0.000651816013222221	0.0109792905084314
GO:0050840	extracellular matrix binding	22/3063	67/18639	0.328358208955224	1.99812884646308	0.000728778908604758	0.0121182851853894
GO:0048306	calcium-dependent protein binding	25/3063	80/18639	0.3125	1.90162830558276	0.000753254818985966	0.0123667278509468
GO:0098632	cell-cell adhesion mediator activity	19/3063	55/18639	0.345454545454545	2.10216365417149	0.000819099410907094	0.0132796491993313
GO:0005201	extracellular matrix structural constituent	44/3063	168/18639	0.261904761904762	1.59374562753603	0.000840788110900163	0.0134629898745372
GO:0002020	protease binding	37/3063	136/18639	0.272058823529412	1.65553523074264	0.000993011356737096	0.0157065332888782
GO:0045295	gamma-catenin binding	7/3063	12/18639	0.583333333333333	3.54970617042116	0.00117992947935111	0.018438175117089
GO:0044389	ubiquitin-like protein ligase binding	74/3063	322/18639	0.229813664596273	1.39846454273912	0.00134351810076374	0.0207445592463163
GO:0043178	alcohol binding	27/3063	92/18639	0.293478260869565	1.78587701741686	0.0013754334788586	0.0209874967303483
GO:0001222	transcription corepressor binding	17/3063	49/18639	0.346938775510204	2.11119550660617	0.00143474577267777	0.0215493027335179
GO:0003774	cytoskeletal motor activity	40/3063	153/18639	0.261437908496732	1.59090472623917	0.00146119999814975	0.0215493027335179
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	15/3063	41/18639	0.365853658536585	2.22629655287738	0.00146209609911301	0.0215493027335179
GO:0004860	protein kinase inhibitor activity	25/3063	84/18639	0.297619047619048	1.81107457674549	0.00163830908323217	0.0238751334938442
GO:0001968	fibronectin binding	12/3063	30/18639	0.4	2.43408423114594	0.00177805044874383	0.0256236825780084
GO:0044325	transmembrane transporter binding	36/3063	136/18639	0.264705882352941	1.61079103531716	0.00194508713081866	0.0274431098274947
GO:0005521	lamin binding	8/3063	16/18639	0.5	3.04260528893242	0.0019466199723435	0.0274431098274947
GO:0019210	kinase inhibitor activity	26/3063	90/18639	0.288888888888889	1.75794972249429	0.00213770355772091	0.0298129195092906
GO:0039706	co-receptor binding	7/3063	13/18639	0.538461538461538	3.27665184961953	0.00219468769725671	0.0302820206738506
GO:0043130	ubiquitin binding	28/3063	100/18639	0.28	1.70385896180215	0.00245451623421506	0.0335106058502835
GO:0001221	transcription coregulator binding	31/3063	115/18639	0.269565217391304	1.640361112294	0.00285085231216368	0.0385162025924614
GO:0120013	lipid transfer activity	20/3063	65/18639	0.307692307692308	1.87237248549687	0.00299321790295942	0.0400227177333853
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	8/3063	17/18639	0.470588235294118	2.86362850723051	0.00315086163457803	0.041279470101492
GO:0070402	NADPH binding	8/3063	17/18639	0.470588235294118	2.86362850723051	0.00315086163457803	0.041279470101492
GO:0043014	alpha-tubulin binding	15/3063	44/18639	0.340909090909091	2.07450360609029	0.00325675937719291	0.042240169122192
GO:0005545	1-phosphatidylinositol binding	7/3063	14/18639	0.5	3.04260528893242	0.00377003713879216	0.0481396986983715
GO:1990782	protein tyrosine kinase binding	31/3063	117/18639	0.264957264957265	1.61232075140009	0.00378585140110555	0.0481396986983715
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	9/3063	21/18639	0.428571428571429	2.6079473905135	0.00382655288933342	0.0481848456064606
GO:0003707	nuclear steroid receptor activity	10/3063	25/18639	0.4	2.43408423114594	0.00424525224843918	0.0527632743581468
GO:0032050	clathrin heavy chain binding	6/3063	11/18639	0.545454545454545	3.31920576974446	0.00427150640524704	0.0527632743581468
GO:0098631	cell adhesion mediator activity	22/3063	76/18639	0.289473684210526	1.7615083251714	0.00439661417890806	0.053796307453243
GO:0030971	receptor tyrosine kinase binding	23/3063	81/18639	0.283950617283951	1.72789929988755	0.00473222037688273	0.0573615871852047
GO:0030276	clathrin binding	15/3063	46/18639	0.326086956521739	1.98430779712984	0.00524534994438654	0.0629927673876791
GO:0032182	ubiquitin-like protein binding	31/3063	120/18639	0.258333333333333	1.57201273261508	0.00566734024362948	0.0674361495044719
GO:0043548	phosphatidylinositol 3-kinase binding	10/3063	26/18639	0.384615384615385	2.34046560687109	0.00589676623786624	0.0689018541487613
GO:0097602	cullin family protein binding	10/3063	26/18639	0.384615384615385	2.34046560687109	0.00589676623786624	0.0689018541487613
GO:0031624	ubiquitin conjugating enzyme binding	11/3063	30/18639	0.366666666666667	2.23124387855044	0.00601033911840383	0.0696018735408015
GO:0045504	dynein heavy chain binding	7/3063	15/18639	0.466666666666667	2.83976493633692	0.00607455134264258	0.0697229477115702
GO:0008200	ion channel inhibitor activity	14/3063	43/18639	0.325581395348837	1.98123135093274	0.0069922014276002	0.0795516250140128
GO:0034452	dynactin binding	6/3063	12/18639	0.5	3.04260528893242	0.00736308333114298	0.0823268886249349
GO:0035197	siRNA binding	6/3063	12/18639	0.5	3.04260528893242	0.00736308333114298	0.0823268886249349
GO:0005158	insulin receptor binding	9/3063	23/18639	0.391304347826087	2.38116935655581	0.00779748712354689	0.0849860571364732
GO:0042171	lysophosphatidic acid acyltransferase activity	9/3063	23/18639	0.391304347826087	2.38116935655581	0.00779748712354689	0.0849860571364732
GO:0071617	lysophospholipid acyltransferase activity	9/3063	23/18639	0.391304347826087	2.38116935655581	0.00779748712354689	0.0849860571364732
GO:0032266	phosphatidylinositol-3-phosphate binding	15/3063	48/18639	0.3125	1.90162830558276	0.00811595375425442	0.0877199334938998
GO:0016248	channel inhibitor activity	14/3063	44/18639	0.318181818181818	1.93620336568427	0.00873540771779027	0.0936349075204461
GO:0051018	protein kinase A binding	16/3063	53/18639	0.30188679245283	1.83704470275165	0.00914118075979209	0.0971812413561503
GO:0034450	ubiquitin-ubiquitin ligase activity	7/3063	16/18639	0.4375	2.66227962781587	0.00928516463065301	0.0979094189102191
GO:0120015	sterol transfer activity	11/3063	32/18639	0.34375	2.09179113614104	0.0103578234807868	0.108339492375649
GO:0050431	transforming growth factor beta binding	9/3063	24/18639	0.375	2.28195396669931	0.0106874330262666	0.110012703452919
GO:0070300	phosphatidic acid binding	9/3063	24/18639	0.375	2.28195396669931	0.0106874330262666	0.110012703452919
GO:0141110	transporter inhibitor activity	14/3063	45/18639	0.311111111111111	1.89317662422462	0.010803939736354	0.110336297937411
GO:0003925	G protein activity	16/3063	54/18639	0.296296296296296	1.8030253564044	0.0110531257394194	0.111131039411062
GO:0050661	NADP binding	16/3063	54/18639	0.296296296296296	1.8030253564044	0.0110531257394194	0.111131039411062
GO:0005548	phospholipid transporter activity	19/3063	68/18639	0.279411764705882	1.70027942616812	0.0116017402861097	0.115749670392956
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	51/3063	229/18639	0.222707423580786	1.35522156974282	0.0126643807583917	0.125387036974305
GO:0030291	protein serine/threonine kinase inhibitor activity	14/3063	46/18639	0.304347826086957	1.85202061065452	0.0132358227703397	0.12948501762101
GO:0030296	protein tyrosine kinase activator activity	11/3063	33/18639	0.333333333333333	2.02840352595495	0.0132779547753233	0.12948501762101
GO:0019894	kinesin binding	13/3063	42/18639	0.30952380952381	1.88351755981531	0.0144073743225391	0.136690630269827
GO:0004862	cAMP-dependent protein kinase inhibitor activity	5/3063	10/18639	0.5	3.04260528893242	0.0145437987488328	0.136690630269827
GO:0050815	phosphoserine residue binding	5/3063	10/18639	0.5	3.04260528893242	0.0145437987488328	0.136690630269827
GO:0070739	protein-glutamic acid ligase activity	5/3063	10/18639	0.5	3.04260528893242	0.0145437987488328	0.136690630269827
GO:0070740	tubulin-glutamic acid ligase activity	5/3063	10/18639	0.5	3.04260528893242	0.0145437987488328	0.136690630269827
GO:0061659	ubiquitin-like protein ligase activity	77/3063	372/18639	0.206989247311828	1.25957315724622	0.0169230214137586	0.157907617076582
GO:0044548	S100 protein binding	6/3063	14/18639	0.428571428571429	2.6079473905135	0.0178104614262355	0.163830982055514
GO:0061665	SUMO ligase activity	6/3063	14/18639	0.428571428571429	2.6079473905135	0.0178104614262355	0.163830982055514
GO:0005227	calcium-activated cation channel activity	9/3063	26/18639	0.346153846153846	2.10641904618398	0.0187658386128154	0.170295840227031
GO:0017022	myosin binding	20/3063	76/18639	0.263157894736842	1.60137120470127	0.0190164790802293	0.170295840227031
GO:0005178	integrin binding	37/3063	161/18639	0.229813664596273	1.39846454273912	0.0190344568443079	0.170295840227031
GO:0016776	phosphotransferase activity, phosphate group as acceptor	12/3063	39/18639	0.307692307692308	1.87237248549687	0.0192511430393204	0.170295840227031
GO:0050321	tau-protein kinase activity	8/3063	22/18639	0.363636363636364	2.21280384649631	0.0192824155214043	0.170295840227031
GO:0003712	transcription coregulator activity	99/3063	495/18639	0.2	1.21704211557297	0.0193010705577282	0.170295840227031
GO:0003924	GTPase activity	69/3063	331/18639	0.208459214501511	1.26851821713799	0.0196152305702722	0.171898338173264
GO:0005154	epidermal growth factor receptor binding	11/3063	35/18639	0.314285714285714	1.91249475304323	0.0209283639734136	0.182175087741728
GO:0016791	phosphatase activity	58/3063	273/18639	0.212454212454212	1.29282862093832	0.0213150362694703	0.18430401361002
GO:0005319	lipid transporter activity	40/3063	178/18639	0.224719101123595	1.36746305120558	0.0217031638812476	0.186417242079325
GO:0016411	acylglycerol O-acyltransferase activity	10/3063	31/18639	0.32258064516129	1.96297115414995	0.0225934055511244	0.189657866784357
GO:0070273	phosphatidylinositol-4-phosphate binding	10/3063	31/18639	0.32258064516129	1.96297115414995	0.0225934055511244	0.189657866784357
GO:0008526	phosphatidylinositol transfer activity	5/3063	11/18639	0.454545454545455	2.76600480812038	0.0231040423684876	0.189657866784357
GO:0019215	intermediate filament binding	5/3063	11/18639	0.454545454545455	2.76600480812038	0.0231040423684876	0.189657866784357
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	5/3063	11/18639	0.454545454545455	2.76600480812038	0.0231040423684876	0.189657866784357
GO:0048407	platelet-derived growth factor binding	5/3063	11/18639	0.454545454545455	2.76600480812038	0.0231040423684876	0.189657866784357
GO:0097493	structural molecule activity conferring elasticity	5/3063	11/18639	0.454545454545455	2.76600480812038	0.0231040423684876	0.189657866784357
GO:0061791	GTPase motor activity	12/3063	40/18639	0.3	1.82556317335945	0.0234991589056916	0.190490056879263
GO:1990606	membrane scission GTPase motor activity	12/3063	40/18639	0.3	1.82556317335945	0.0234991589056916	0.190490056879263
GO:0008252	nucleotidase activity	6/3063	15/18639	0.4	2.43408423114594	0.0256344014819641	0.201447444009494
GO:0120283	protein serine/threonine kinase binding	6/3063	15/18639	0.4	2.43408423114594	0.0256344014819641	0.201447444009494
GO:0004879	nuclear receptor activity	16/3063	59/18639	0.271186440677966	1.65022659738707	0.0257296122528299	0.201447444009494
GO:0005484	SNAP receptor activity	11/3063	36/18639	0.305555555555556	1.85936989879203	0.0257827877452397	0.201447444009494
GO:0044390	ubiquitin-like protein conjugating enzyme binding	11/3063	36/18639	0.305555555555556	1.85936989879203	0.0257827877452397	0.201447444009494
GO:0045505	dynein intermediate chain binding	11/3063	36/18639	0.305555555555556	1.85936989879203	0.0257827877452397	0.201447444009494
GO:0008574	plus-end-directed microtubule motor activity	7/3063	19/18639	0.368421052631579	2.24191968658178	0.026081497887286	0.20256109437012
GO:0140767	enzyme-substrate adaptor activity	32/3063	139/18639	0.23021582733813	1.40091178770989	0.0270172066594726	0.20784422653968
GO:0005516	calmodulin binding	45/3063	207/18639	0.217391304347826	1.32287186475323	0.0270822469431041	0.20784422653968
GO:0008378	galactosyltransferase activity	10/3063	32/18639	0.3125	1.90162830558276	0.0281550337649142	0.214806345841728
GO:0061650	ubiquitin-like protein conjugating enzyme activity	12/3063	41/18639	0.292682926829268	1.7810372423019	0.0283973199629483	0.215387859602012
GO:0051117	ATPase binding	21/3063	84/18639	0.25	1.52130264446621	0.0287031716729797	0.215761376997375
GO:0008374	O-acyltransferase activity	15/3063	55/18639	0.272727272727273	1.65960288487223	0.0287792738786013	0.215761376997375
GO:0098531	ligand-modulated transcription factor activity	16/3063	60/18639	0.266666666666667	1.62272282076396	0.0298966017731543	0.222849956895294
GO:0043394	proteoglycan binding	11/3063	37/18639	0.297297297297297	1.80911665828414	0.0314015696346869	0.231191787222653
GO:0097110	scaffold protein binding	18/3063	70/18639	0.257142857142857	1.5647684343081	0.0314225945022295	0.231191787222653
GO:0004857	enzyme inhibitor activity	83/3063	416/18639	0.199519230769231	1.21411653356438	0.031550459782891	0.231191787222653
GO:0030552	cAMP binding	8/3063	24/18639	0.333333333333333	2.02840352595495	0.0327678494872591	0.23876348755604
GO:0048487	beta-tubulin binding	12/3063	42/18639	0.285714285714286	1.73863159367567	0.033993298219112	0.246308982068091
GO:0008603	cAMP-dependent protein kinase regulator activity	5/3063	12/18639	0.416666666666667	2.53550440744368	0.0343475845380194	0.246738778484507
GO:0015095	magnesium ion transmembrane transporter activity	7/3063	20/18639	0.35	2.12982370225269	0.0345783758702725	0.246738778484507
GO:0071889	14-3-3 protein binding	10/3063	33/18639	0.303030303030303	1.84400320541359	0.0346233289777797	0.246738778484507
GO:1902936	phosphatidylinositol bisphosphate binding	26/3063	111/18639	0.234234234234234	1.42536463986023	0.0353902112195345	0.248490782917826
GO:0005024	transforming growth factor beta receptor activity	6/3063	16/18639	0.375	2.28195396669931	0.0354439435927508	0.248490782917826
GO:0070411	I-SMAD binding	6/3063	16/18639	0.375	2.28195396669931	0.0354439435927508	0.248490782917826
GO:0008013	beta-catenin binding	25/3063	106/18639	0.235849056603774	1.43519117402473	0.0357403084258691	0.249221398001893
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	21/3063	86/18639	0.244186046511628	1.48592351319955	0.0364512902403275	0.252819911452967
GO:0035250	UDP-galactosyltransferase activity	9/3063	29/18639	0.310344827586207	1.88851362761323	0.0380110819077256	0.262236027842128
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	29/3063	128/18639	0.2265625	1.3786805215475	0.0410758822472781	0.281880525263067
GO:0004709	MAP kinase kinase kinase activity	8/3063	25/18639	0.32	1.94726738491675	0.0414533505571249	0.28297366143469
GO:0022853	active monoatomic ion transmembrane transporter activity	27/3063	118/18639	0.228813559322034	1.39237869154534	0.042478281506024	0.288451995357661
GO:0005544	calcium-dependent phospholipid binding	14/3063	53/18639	0.264150943396226	1.60741411490769	0.0436510687682342	0.294872063502082
GO:0010314	phosphatidylinositol-5-phosphate binding	7/3063	21/18639	0.333333333333333	2.02840352595495	0.0447244564522601	0.300512473186902
GO:0035591	signaling adaptor activity	29/3063	129/18639	0.224806201550388	1.36799307564403	0.0449494370071388	0.300512473186902
GO:0043539	protein serine/threonine kinase activator activity	18/3063	73/18639	0.246575342465753	1.50046288221325	0.0460036749526523	0.303536311105682
GO:0022839	monoatomic ion-gated channel activity	9/3063	30/18639	0.3	1.82556317335945	0.046642216329674	0.303536311105682
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	6/3063	17/18639	0.352941176470588	2.14772138042288	0.0473701800644845	0.303536311105682
GO:0005092	GDP-dissociation inhibitor activity	6/3063	17/18639	0.352941176470588	2.14772138042288	0.0473701800644845	0.303536311105682
GO:0032977	membrane insertase activity	6/3063	17/18639	0.352941176470588	2.14772138042288	0.0473701800644845	0.303536311105682
GO:0003714	transcription corepressor activity	43/3063	204/18639	0.21078431372549	1.28266693553033	0.0473809212132288	0.303536311105682
GO:0003954	NADH dehydrogenase activity	12/3063	44/18639	0.272727272727273	1.65960288487223	0.0474502756383164	0.303536311105682
GO:0030020	extracellular matrix structural constituent conferring tensile strength	12/3063	44/18639	0.272727272727273	1.65960288487223	0.0474502756383164	0.303536311105682
GO:0042578	phosphoric ester hydrolase activity	72/3063	363/18639	0.198347107438017	1.20698391627071	0.0475904940856629	0.303536311105682
GO:0008253	5'-nucleotidase activity	5/3063	13/18639	0.384615384615385	2.34046560687109	0.048444114417021	0.303536311105682
GO:0019855	calcium channel inhibitor activity	5/3063	13/18639	0.384615384615385	2.34046560687109	0.048444114417021	0.303536311105682
GO:0043560	insulin receptor substrate binding	5/3063	13/18639	0.384615384615385	2.34046560687109	0.048444114417021	0.303536311105682
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	5/3063	13/18639	0.384615384615385	2.34046560687109	0.048444114417021	0.303536311105682
GO:0061630	ubiquitin protein ligase activity	70/3063	353/18639	0.198300283286119	1.20669898144629	0.0503678251315167	0.314072448055659
GO:0030507	spectrin binding	8/3063	26/18639	0.307692307692308	1.87237248549687	0.0515366891990402	0.315297574958279
GO:0034237	protein kinase A regulatory subunit binding	8/3063	26/18639	0.307692307692308	1.87237248549687	0.0515366891990402	0.315297574958279
GO:0070412	R-SMAD binding	8/3063	26/18639	0.307692307692308	1.87237248549687	0.0515366891990402	0.315297574958279
GO:0120014	phospholipid transfer activity	8/3063	26/18639	0.307692307692308	1.87237248549687	0.0515366891990402	0.315297574958279
GO:0140303	intramembrane lipid transporter activity	12/3063	45/18639	0.266666666666667	1.62272282076396	0.0553850465911695	0.337250729712426
GO:0019001	guanyl nucleotide binding	78/3063	400/18639	0.195	1.18661606268364	0.0565813911769102	0.338280365557592
GO:0032561	guanyl ribonucleotide binding	78/3063	400/18639	0.195	1.18661606268364	0.0565813911769102	0.338280365557592
GO:0008093	cytoskeletal anchor activity	7/3063	22/18639	0.318181818181818	1.93620336568427	0.0565974088866595	0.338280365557592
GO:0016881	acid-amino acid ligase activity	7/3063	22/18639	0.318181818181818	1.93620336568427	0.0565974088866595	0.338280365557592
GO:0005525	GTP binding	74/3063	378/18639	0.195767195767196	1.19128461048148	0.0576221857883196	0.342825573245186
GO:0000149	SNARE binding	24/3063	106/18639	0.226415094339623	1.37778352706374	0.0592688968749381	0.351012599300433
GO:0004721	phosphoprotein phosphatase activity	37/3063	175/18639	0.211428571428571	1.28658737931999	0.0597012585606889	0.35196605615097
GO:0016409	palmitoyltransferase activity	10/3063	36/18639	0.277777777777778	1.69033627162912	0.0600199968803154	0.352244054089453
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	27/3063	122/18639	0.221311475409836	1.34672693116681	0.0608923362673417	0.352899380522943
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	6/3063	18/18639	0.333333333333333	2.02840352595495	0.0614921048559639	0.352899380522943
GO:0004706	JUN kinase kinase kinase activity	6/3063	18/18639	0.333333333333333	2.02840352595495	0.0614921048559639	0.352899380522943
GO:0017075	syntaxin-1 binding	6/3063	18/18639	0.333333333333333	2.02840352595495	0.0614921048559639	0.352899380522943
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	6/3063	18/18639	0.333333333333333	2.02840352595495	0.0614921048559639	0.352899380522943
GO:0000287	magnesium ion binding	47/3063	230/18639	0.204347826086957	1.24349955286803	0.0625392512227212	0.3573277922285
GO:0042043	neurexin family protein binding	5/3063	14/18639	0.357142857142857	2.17328949209459	0.0654628105230129	0.364882847757681
GO:0070742	C2H2 zinc finger domain binding	5/3063	14/18639	0.357142857142857	2.17328949209459	0.0654628105230129	0.364882847757681
GO:0019212	phosphatase inhibitor activity	14/3063	56/18639	0.25	1.52130264446621	0.0657562228193802	0.364882847757681
GO:0140297	DNA-binding transcription factor binding	93/3063	488/18639	0.190573770491803	1.15968152406031	0.0658503922816276	0.364882847757681
GO:0005522	profilin binding	4/3063	10/18639	0.4	2.43408423114594	0.0666748148948115	0.364882847757681
GO:0005528	FK506 binding	4/3063	10/18639	0.4	2.43408423114594	0.0666748148948115	0.364882847757681
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	4/3063	10/18639	0.4	2.43408423114594	0.0666748148948115	0.364882847757681
GO:0019911	structural constituent of myelin sheath	4/3063	10/18639	0.4	2.43408423114594	0.0666748148948115	0.364882847757681
GO:0031419	cobalamin binding	4/3063	10/18639	0.4	2.43408423114594	0.0666748148948115	0.364882847757681
GO:0070513	death domain binding	4/3063	10/18639	0.4	2.43408423114594	0.0666748148948115	0.364882847757681
GO:0030551	cyclic nucleotide binding	10/3063	37/18639	0.27027027027027	1.64465150753104	0.0706194143786964	0.384846136341047
GO:0004713	protein tyrosine kinase activity	30/3063	140/18639	0.214285714285714	1.30397369525675	0.0720515603886637	0.390779141382527
GO:0031492	nucleosomal DNA binding	11/3063	42/18639	0.261904761904762	1.59374562753603	0.0726120069955197	0.390779141382527
GO:0051879	Hsp90 protein binding	11/3063	42/18639	0.261904761904762	1.59374562753603	0.0726120069955197	0.390779141382527
GO:0004725	protein tyrosine phosphatase activity	22/3063	98/18639	0.224489795918367	1.36606768074517	0.0741640380098167	0.397106238039933
GO:0005080	protein kinase C binding	13/3063	52/18639	0.25	1.52130264446621	0.0744000122156545	0.397106238039933
GO:0051019	mitogen-activated protein kinase binding	8/3063	28/18639	0.285714285714286	1.73863159367567	0.0760847163503204	0.402783171862717
GO:0097718	disordered domain specific binding	8/3063	28/18639	0.285714285714286	1.73863159367567	0.0760847163503204	0.402783171862717
GO:0042577	lipid phosphatase activity	6/3063	19/18639	0.315789473684211	1.92164544564153	0.0778354619184305	0.405432104852226
GO:0050145	nucleoside monophosphate kinase activity	6/3063	19/18639	0.315789473684211	1.92164544564153	0.0778354619184305	0.405432104852226
GO:0097001	ceramide binding	6/3063	19/18639	0.315789473684211	1.92164544564153	0.0778354619184305	0.405432104852226
GO:1990380	K48-linked deubiquitinase activity	6/3063	19/18639	0.315789473684211	1.92164544564153	0.0778354619184305	0.405432104852226
GO:0017124	SH3 domain binding	25/3063	115/18639	0.217391304347826	1.32287186475323	0.0821381543897717	0.417740323647616
GO:0035401	histone H3Y41 kinase activity	25/3063	115/18639	0.217391304347826	1.32287186475323	0.0821381543897717	0.417740323647616
GO:0140801	histone H2AXY142 kinase activity	25/3063	115/18639	0.217391304347826	1.32287186475323	0.0821381543897717	0.417740323647616
GO:0003777	microtubule motor activity	16/3063	68/18639	0.235294117647059	1.43181425361526	0.0824070242938629	0.417740323647616
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	16/3063	68/18639	0.235294117647059	1.43181425361526	0.0824070242938629	0.417740323647616
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	14/3063	58/18639	0.241379310344828	1.46884393258806	0.0840282085987548	0.417740323647616
GO:0140693	molecular condensate scaffold activity	12/3063	48/18639	0.25	1.52130264446621	0.0843332683650924	0.417740323647616
GO:0004864	protein phosphatase inhibitor activity	13/3063	53/18639	0.245283018867925	1.49259882098572	0.0843934188360662	0.417740323647616
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	20/3063	89/18639	0.224719101123595	1.36746305120558	0.0848587299364388	0.417740323647616
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	20/3063	89/18639	0.224719101123595	1.36746305120558	0.0848587299364388	0.417740323647616
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	5/3063	15/18639	0.333333333333333	2.02840352595495	0.0853770150435372	0.417740323647616
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	5/3063	15/18639	0.333333333333333	2.02840352595495	0.0853770150435372	0.417740323647616
GO:0015929	hexosaminidase activity	5/3063	15/18639	0.333333333333333	2.02840352595495	0.0853770150435372	0.417740323647616
GO:0031005	filamin binding	5/3063	15/18639	0.333333333333333	2.02840352595495	0.0853770150435372	0.417740323647616
GO:0048531	beta-1,3-galactosyltransferase activity	5/3063	15/18639	0.333333333333333	2.02840352595495	0.0853770150435372	0.417740323647616
GO:0050699	WW domain binding	7/3063	24/18639	0.291666666666667	1.77485308521058	0.08567380577507	0.417740323647616
GO:0070840	dynein complex binding	7/3063	24/18639	0.291666666666667	1.77485308521058	0.08567380577507	0.417740323647616
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	8/3063	29/18639	0.275862068965517	1.67867878010064	0.0905889580427377	0.425696780489792
GO:0016417	S-acyltransferase activity	8/3063	29/18639	0.275862068965517	1.67867878010064	0.0905889580427377	0.425696780489792
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	8/3063	29/18639	0.275862068965517	1.67867878010064	0.0905889580427377	0.425696780489792
GO:0097472	cyclin-dependent protein kinase activity	8/3063	29/18639	0.275862068965517	1.67867878010064	0.0905889580427377	0.425696780489792
GO:0008432	JUN kinase binding	4/3063	11/18639	0.363636363636364	2.21280384649631	0.0915723991955681	0.425696780489792
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	4/3063	11/18639	0.363636363636364	2.21280384649631	0.0915723991955681	0.425696780489792
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4/3063	11/18639	0.363636363636364	2.21280384649631	0.0915723991955681	0.425696780489792
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	4/3063	11/18639	0.363636363636364	2.21280384649631	0.0915723991955681	0.425696780489792
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	4/3063	11/18639	0.363636363636364	2.21280384649631	0.0915723991955681	0.425696780489792
GO:0019107	myristoyltransferase activity	4/3063	11/18639	0.363636363636364	2.21280384649631	0.0915723991955681	0.425696780489792
GO:0032794	GTPase activating protein binding	4/3063	11/18639	0.363636363636364	2.21280384649631	0.0915723991955681	0.425696780489792
GO:0045294	alpha-catenin binding	4/3063	11/18639	0.363636363636364	2.21280384649631	0.0915723991955681	0.425696780489792
GO:0047676	arachidonate-CoA ligase activity	4/3063	11/18639	0.363636363636364	2.21280384649631	0.0915723991955681	0.425696780489792
GO:0140793	histone H2AXY142 phosphatase activity	20/3063	90/18639	0.222222222222222	1.3522690173033	0.0929879511042957	0.430733473508113
GO:0045309	protein phosphorylated amino acid binding	14/3063	59/18639	0.23728813559322	1.44394827271369	0.0942629737580329	0.433542826114073
GO:0070888	E-box binding	14/3063	59/18639	0.23728813559322	1.44394827271369	0.0942629737580329	0.433542826114073
GO:0001223	transcription coactivator binding	11/3063	44/18639	0.25	1.52130264446621	0.0957946615715736	0.435530851453864
GO:0019205	nucleobase-containing compound kinase activity	11/3063	44/18639	0.25	1.52130264446621	0.0957946615715736	0.435530851453864
GO:0030547	signaling receptor inhibitor activity	11/3063	44/18639	0.25	1.52130264446621	0.0957946615715736	0.435530851453864
GO:0030742	GTP-dependent protein binding	6/3063	20/18639	0.3	1.82556317335945	0.0963742130819268	0.435530851453864
GO:0031418	L-ascorbic acid binding	6/3063	20/18639	0.3	1.82556317335945	0.0963742130819268	0.435530851453864
GO:0015399	primary active transmembrane transporter activity	34/3063	166/18639	0.204819277108434	1.24636843161087	0.0977000413307857	0.439989422243157
GO:0031490	chromatin DNA binding	27/3063	128/18639	0.2109375	1.28359910626836	0.0980881525705513	0.440208767764723
GO:0017025	TBP-class protein binding	7/3063	25/18639	0.28	1.70385896180215	0.102870649470938	0.455369393733126
GO:0019706	protein-cysteine S-palmitoyltransferase activity	7/3063	25/18639	0.28	1.70385896180215	0.102870649470938	0.455369393733126
GO:0019707	protein-cysteine S-acyltransferase activity	7/3063	25/18639	0.28	1.70385896180215	0.102870649470938	0.455369393733126
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	7/3063	25/18639	0.28	1.70385896180215	0.102870649470938	0.455369393733126
GO:0001098	basal transcription machinery binding	14/3063	60/18639	0.233333333333333	1.41988246816846	0.105235983684129	0.460852848675871
GO:0001099	basal RNA polymerase II transcription machinery binding	14/3063	60/18639	0.233333333333333	1.41988246816846	0.105235983684129	0.460852848675871
GO:0048019	receptor antagonist activity	8/3063	30/18639	0.266666666666667	1.62272282076396	0.106569591392943	0.460852848675871
GO:0051721	protein phosphatase 2A binding	8/3063	30/18639	0.266666666666667	1.62272282076396	0.106569591392943	0.460852848675871
GO:0001618	virus receptor activity	18/3063	81/18639	0.222222222222222	1.3522690173033	0.10682618303974	0.460852848675871
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/3063	16/18639	0.3125	1.90162830558276	0.108073865702986	0.460852848675871
GO:0005324	long-chain fatty acid transmembrane transporter activity	5/3063	16/18639	0.3125	1.90162830558276	0.108073865702986	0.460852848675871
GO:0008142	oxysterol binding	5/3063	16/18639	0.3125	1.90162830558276	0.108073865702986	0.460852848675871
GO:0043023	ribosomal large subunit binding	5/3063	16/18639	0.3125	1.90162830558276	0.108073865702986	0.460852848675871
GO:0043015	gamma-tubulin binding	9/3063	35/18639	0.257142857142857	1.5647684343081	0.108443612725694	0.460852848675871
GO:0061631	ubiquitin conjugating enzyme activity	9/3063	35/18639	0.257142857142857	1.5647684343081	0.108443612725694	0.460852848675871
GO:0140566	histone reader activity	9/3063	35/18639	0.257142857142857	1.5647684343081	0.108443612725694	0.460852848675871
GO:0004715	non-membrane spanning protein tyrosine kinase activity	11/3063	45/18639	0.244444444444444	1.48749591903363	0.108868360535822	0.460852848675871
GO:0032451	demethylase activity	10/3063	40/18639	0.25	1.52130264446621	0.109083904813795	0.460852848675871
GO:0052689	carboxylic ester hydrolase activity	20/3063	92/18639	0.217391304347826	1.32287186475323	0.110703243493076	0.466175671462726
GO:1901681	sulfur compound binding	53/3063	275/18639	0.192727272727273	1.17278603864304	0.116734805692197	0.478066594543521
GO:0140272	exogenous protein binding	18/3063	82/18639	0.219512195121951	1.33577793172643	0.116857794309844	0.478066594543521
GO:0019905	syntaxin binding	14/3063	61/18639	0.229508196721311	1.39660570639521	0.116945212302045	0.478066594543521
GO:0009931	calcium-dependent protein serine/threonine kinase activity	6/3063	21/18639	0.285714285714286	1.73863159367567	0.117034115733793	0.478066594543521
GO:0140789	histone phosphatase activity	28/3063	136/18639	0.205882352941176	1.25283747191335	0.117547497196323	0.478066594543521
GO:0004859	phospholipase inhibitor activity	4/3063	12/18639	0.333333333333333	2.02840352595495	0.120184806524342	0.478066594543521
GO:0005049	nuclear export signal receptor activity	4/3063	12/18639	0.333333333333333	2.02840352595495	0.120184806524342	0.478066594543521
GO:0005078	MAP-kinase scaffold activity	4/3063	12/18639	0.333333333333333	2.02840352595495	0.120184806524342	0.478066594543521
GO:0005095	GTPase inhibitor activity	4/3063	12/18639	0.333333333333333	2.02840352595495	0.120184806524342	0.478066594543521
GO:0005165	neurotrophin receptor binding	4/3063	12/18639	0.333333333333333	2.02840352595495	0.120184806524342	0.478066594543521
GO:0005247	voltage-gated chloride channel activity	4/3063	12/18639	0.333333333333333	2.02840352595495	0.120184806524342	0.478066594543521
GO:0005527	macrolide binding	4/3063	12/18639	0.333333333333333	2.02840352595495	0.120184806524342	0.478066594543521
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	4/3063	12/18639	0.333333333333333	2.02840352595495	0.120184806524342	0.478066594543521
GO:0031543	peptidyl-proline dioxygenase activity	4/3063	12/18639	0.333333333333333	2.02840352595495	0.120184806524342	0.478066594543521
GO:0035014	phosphatidylinositol 3-kinase regulator activity	4/3063	12/18639	0.333333333333333	2.02840352595495	0.120184806524342	0.478066594543521
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	4/3063	12/18639	0.333333333333333	2.02840352595495	0.120184806524342	0.478066594543521
GO:0051219	phosphoprotein binding	20/3063	93/18639	0.21505376344086	1.30864743609997	0.120291309445264	0.478066594543521
GO:0005539	glycosaminoglycan binding	47/3063	242/18639	0.194214876033058	1.18183841801507	0.121160298852299	0.478066594543521
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	7/3063	26/18639	0.269230769230769	1.63832592480976	0.121783161150058	0.478066594543521
GO:0008157	protein phosphatase 1 binding	7/3063	26/18639	0.269230769230769	1.63832592480976	0.121783161150058	0.478066594543521
GO:0050681	nuclear androgen receptor binding	7/3063	26/18639	0.269230769230769	1.63832592480976	0.121783161150058	0.478066594543521
GO:0005518	collagen binding	16/3063	72/18639	0.222222222222222	1.3522690173033	0.123138553361414	0.478066594543521
GO:0016651	oxidoreductase activity, acting on NAD(P)H	19/3063	88/18639	0.215909090909091	1.31385228385718	0.123822075351484	0.478066594543521
GO:0017147	Wnt-protein binding	8/3063	31/18639	0.258064516129032	1.57037692331996	0.123991930592705	0.478066594543521
GO:0001727	lipid kinase activity	10/3063	41/18639	0.24390243902439	1.48419770191825	0.124111750473611	0.478066594543521
GO:0008137	NADH dehydrogenase (ubiquinone) activity	10/3063	41/18639	0.24390243902439	1.48419770191825	0.124111750473611	0.478066594543521
GO:0000993	RNA polymerase II complex binding	9/3063	36/18639	0.25	1.52130264446621	0.124584818007487	0.478066594543521
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	9/3063	36/18639	0.25	1.52130264446621	0.124584818007487	0.478066594543521
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	9/3063	36/18639	0.25	1.52130264446621	0.124584818007487	0.478066594543521
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	9/3063	36/18639	0.25	1.52130264446621	0.124584818007487	0.478066594543521
GO:0008234	cysteine-type peptidase activity	37/3063	187/18639	0.197860962566845	1.20402562235828	0.127372173028061	0.484707034962441
GO:0001540	amyloid-beta binding	18/3063	83/18639	0.216867469879518	1.31968422170563	0.127436467943093	0.484707034962441
GO:0030165	PDZ domain binding	18/3063	83/18639	0.216867469879518	1.31968422170563	0.127436467943093	0.484707034962441
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	5/3063	17/18639	0.294117647058824	1.78976781701907	0.133367068052361	0.501382861634529
GO:0004659	prenyltransferase activity	5/3063	17/18639	0.294117647058824	1.78976781701907	0.133367068052361	0.501382861634529
GO:0008484	sulfuric ester hydrolase activity	5/3063	17/18639	0.294117647058824	1.78976781701907	0.133367068052361	0.501382861634529
GO:0051787	misfolded protein binding	5/3063	17/18639	0.294117647058824	1.78976781701907	0.133367068052361	0.501382861634529
GO:0019783	ubiquitin-like protein peptidase activity	26/3063	127/18639	0.204724409448819	1.24579114192509	0.133973252253977	0.502206092986731
GO:0030159	signaling receptor complex adaptor activity	12/3063	52/18639	0.230769230769231	1.40427936412265	0.135280854186677	0.505646305130031
GO:0043495	protein-membrane adaptor activity	11/3063	47/18639	0.234042553191489	1.42419822035135	0.137924276470819	0.512865326375319
GO:0003713	transcription coactivator activity	49/3063	256/18639	0.19140625	1.16474733716944	0.138003083195826	0.512865326375319
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	6/3063	22/18639	0.272727272727273	1.65960288487223	0.139697880801469	0.516205559542749
GO:0140035	ubiquitin-like protein reader activity	6/3063	22/18639	0.272727272727273	1.65960288487223	0.139697880801469	0.516205559542749
GO:0043175	RNA polymerase core enzyme binding	10/3063	42/18639	0.238095238095238	1.44885966139639	0.140205420310515	0.516609176541871
GO:0030280	structural constituent of skin epidermis	9/3063	37/18639	0.243243243243243	1.48018635677793	0.141930840602455	0.517438787266271
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	7/3063	27/18639	0.259259259259259	1.57764718685385	0.142332697895864	0.517438787266271
GO:0051059	NF-kappaB binding	8/3063	32/18639	0.25	1.52130264446621	0.14280117681474	0.517438787266271
GO:0140142	nucleocytoplasmic carrier activity	8/3063	32/18639	0.25	1.52130264446621	0.14280117681474	0.517438787266271
GO:0070851	growth factor receptor binding	28/3063	139/18639	0.201438848920863	1.22579781424615	0.142824275899248	0.517438787266271
GO:0140101	catalytic activity, acting on a tRNA	28/3063	139/18639	0.201438848920863	1.22579781424615	0.142824275899248	0.517438787266271
GO:0061980	regulatory RNA binding	13/3063	58/18639	0.224137931034483	1.36392650883177	0.146379740213359	0.528842682609266
GO:0031491	nucleosome binding	16/3063	74/18639	0.216216216216216	1.31572120602483	0.147245828166315	0.530493997588085
GO:0140296	general transcription initiation factor binding	12/3063	53/18639	0.226415094339623	1.37778352706374	0.150174737703929	0.539547464825475
GO:0017154	semaphorin receptor activity	4/3063	13/18639	0.307692307692308	1.87237248549687	0.152069558572041	0.543344951702306
GO:0140852	histone ubiquitin ligase activity	4/3063	13/18639	0.307692307692308	1.87237248549687	0.152069558572041	0.543344951702306
GO:0008375	acetylglucosaminyltransferase activity	10/3063	43/18639	0.232558139534884	1.41516525066624	0.157325679468775	0.559702676795605
GO:0000146	microfilament motor activity	9/3063	38/18639	0.236842105263158	1.44123408423115	0.160428574428523	0.559702676795605
GO:0008308	voltage-gated monoatomic anion channel activity	5/3063	18/18639	0.277777777777778	1.69033627162912	0.16101128466636	0.559702676795605
GO:0017128	phospholipid scramblase activity	5/3063	18/18639	0.277777777777778	1.69033627162912	0.16101128466636	0.559702676795605
GO:0050811	GABA receptor binding	5/3063	18/18639	0.277777777777778	1.69033627162912	0.16101128466636	0.559702676795605
GO:1990381	ubiquitin-specific protease binding	5/3063	18/18639	0.277777777777778	1.69033627162912	0.16101128466636	0.559702676795605
GO:0031593	polyubiquitin modification-dependent protein binding	13/3063	59/18639	0.220338983050847	1.340809110377	0.161108391602908	0.559702676795605
GO:0070063	RNA polymerase binding	13/3063	59/18639	0.220338983050847	1.340809110377	0.161108391602908	0.559702676795605
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	8/3063	33/18639	0.242424242424242	1.47520256433087	0.162924108425086	0.559702676795605
GO:0140311	protein sequestering activity	8/3063	33/18639	0.242424242424242	1.47520256433087	0.162924108425086	0.559702676795605
GO:0017134	fibroblast growth factor binding	6/3063	23/18639	0.260869565217391	1.58744623770387	0.16421140278159	0.559702676795605
GO:0043274	phospholipase binding	6/3063	23/18639	0.260869565217391	1.58744623770387	0.16421140278159	0.559702676795605
GO:0140103	catalytic activity, acting on a glycoprotein	6/3063	23/18639	0.260869565217391	1.58744623770387	0.16421140278159	0.559702676795605
GO:0019789	SUMO transferase activity	7/3063	28/18639	0.25	1.52130264446621	0.164415358411045	0.559702676795605
GO:0045499	chemorepellent activity	7/3063	28/18639	0.25	1.52130264446621	0.164415358411045	0.559702676795605
GO:0051959	dynein light intermediate chain binding	7/3063	28/18639	0.25	1.52130264446621	0.164415358411045	0.559702676795605
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	7/3063	28/18639	0.25	1.52130264446621	0.164415358411045	0.559702676795605
GO:0141052	histone H3 demethylase activity	7/3063	28/18639	0.25	1.52130264446621	0.164415358411045	0.559702676795605
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	12/3063	54/18639	0.222222222222222	1.3522690173033	0.165884147069078	0.563224446985847
GO:0141108	transporter regulator activity	33/3063	170/18639	0.194117647058824	1.18124675923259	0.17063062688296	0.577827475371277
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	13/3063	60/18639	0.216666666666667	1.31846229187072	0.176562461878314	0.596255928219994
GO:0016922	nuclear receptor binding	27/3063	137/18639	0.197080291970803	1.19927507738942	0.176991929348264	0.596255928219994
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	9/3063	39/18639	0.230769230769231	1.40427936412265	0.180012113263653	0.603316745207682
GO:0099106	ion channel regulator activity	31/3063	160/18639	0.19375	1.17900954946131	0.182411944842414	0.603316745207682
GO:0008376	acetylgalactosaminyltransferase activity	8/3063	34/18639	0.235294117647059	1.43181425361526	0.184271123061787	0.603316745207682
GO:0030332	cyclin binding	8/3063	34/18639	0.235294117647059	1.43181425361526	0.184271123061787	0.603316745207682
GO:0052866	phosphatidylinositol phosphate phosphatase activity	8/3063	34/18639	0.235294117647059	1.43181425361526	0.184271123061787	0.603316745207682
GO:0004065	arylsulfatase activity	4/3063	14/18639	0.285714285714286	1.73863159367567	0.186712257791652	0.603316745207682
GO:0008191	metalloendopeptidase inhibitor activity	4/3063	14/18639	0.285714285714286	1.73863159367567	0.186712257791652	0.603316745207682
GO:0008195	phosphatidate phosphatase activity	4/3063	14/18639	0.285714285714286	1.73863159367567	0.186712257791652	0.603316745207682
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	4/3063	14/18639	0.285714285714286	1.73863159367567	0.186712257791652	0.603316745207682
GO:0003785	actin monomer binding	7/3063	29/18639	0.241379310344828	1.46884393258806	0.187905576710052	0.603316745207682
GO:0004197	cysteine-type endopeptidase activity	18/3063	88/18639	0.204545454545455	1.24470216365417	0.188252623768542	0.603316745207682
GO:0035035	histone acetyltransferase binding	6/3063	24/18639	0.25	1.52130264446621	0.190390601783763	0.603316745207682
GO:0042625	ATPase-coupled ion transmembrane transporter activity	6/3063	24/18639	0.25	1.52130264446621	0.190390601783763	0.603316745207682
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	6/3063	24/18639	0.25	1.52130264446621	0.190390601783763	0.603316745207682
GO:0046961	proton-transporting ATPase activity, rotational mechanism	6/3063	24/18639	0.25	1.52130264446621	0.190390601783763	0.603316745207682
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	6/3063	24/18639	0.25	1.52130264446621	0.190390601783763	0.603316745207682
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	5/3063	19/18639	0.263157894736842	1.60137120470127	0.190716935647764	0.603316745207682
GO:0015245	fatty acid transmembrane transporter activity	5/3063	19/18639	0.263157894736842	1.60137120470127	0.190716935647764	0.603316745207682
GO:0016918	retinal binding	5/3063	19/18639	0.263157894736842	1.60137120470127	0.190716935647764	0.603316745207682
GO:0022840	leak channel activity	5/3063	19/18639	0.263157894736842	1.60137120470127	0.190716935647764	0.603316745207682
GO:0022842	narrow pore channel activity	5/3063	19/18639	0.263157894736842	1.60137120470127	0.190716935647764	0.603316745207682
GO:0042800	histone H3K4 methyltransferase activity	5/3063	19/18639	0.263157894736842	1.60137120470127	0.190716935647764	0.603316745207682
GO:0043395	heparan sulfate proteoglycan binding	5/3063	19/18639	0.263157894736842	1.60137120470127	0.190716935647764	0.603316745207682
GO:0120227	acyl-CoA binding	5/3063	19/18639	0.263157894736842	1.60137120470127	0.190716935647764	0.603316745207682
GO:0140036	ubiquitin-modified protein reader activity	5/3063	19/18639	0.263157894736842	1.60137120470127	0.190716935647764	0.603316745207682
GO:0033218	amide binding	46/3063	247/18639	0.186234817813765	1.13327808332706	0.19651981771149	0.620161079250128
GO:0140030	modification-dependent protein binding	33/3063	173/18639	0.190751445086705	1.16076271138462	0.198785998201572	0.625789902105435
GO:0015036	disulfide oxidoreductase activity	9/3063	40/18639	0.225	1.36917238001959	0.200604173781353	0.628462834286026
GO:0050997	quaternary ammonium group binding	9/3063	40/18639	0.225	1.36917238001959	0.200604173781353	0.628462834286026
GO:0019199	transmembrane receptor protein kinase activity	16/3063	78/18639	0.205128205128205	1.24824832366458	0.202475806583008	0.632797882260629
GO:0016247	channel regulator activity	32/3063	168/18639	0.19047619047619	1.15908772911711	0.205553514362173	0.640872375307062
GO:0005030	neurotrophin receptor activity	11/3063	51/18639	0.215686274509804	1.31249639914732	0.206798504216556	0.643207817671158
GO:0008276	protein methyltransferase activity	19/3063	95/18639	0.2	1.21704211557297	0.208090893642887	0.645679160418239
GO:0031210	phosphatidylcholine binding	7/3063	30/18639	0.233333333333333	1.41988246816846	0.212660007023955	0.647230320878799
GO:0032452	histone demethylase activity	7/3063	30/18639	0.233333333333333	1.41988246816846	0.212660007023955	0.647230320878799
GO:0070566	adenylyltransferase activity	7/3063	30/18639	0.233333333333333	1.41988246816846	0.212660007023955	0.647230320878799
GO:0015662	P-type ion transporter activity	6/3063	25/18639	0.24	1.46045053868756	0.218028481461498	0.647230320878799
GO:0120020	cholesterol transfer activity	6/3063	25/18639	0.24	1.46045053868756	0.218028481461498	0.647230320878799
GO:0140358	P-type transmembrane transporter activity	6/3063	25/18639	0.24	1.46045053868756	0.218028481461498	0.647230320878799
GO:0003680	minor groove of adenine-thymine-rich DNA binding	3/3063	10/18639	0.3	1.82556317335945	0.218249029907489	0.647230320878799
GO:0004090	carbonyl reductase (NADPH) activity	3/3063	10/18639	0.3	1.82556317335945	0.218249029907489	0.647230320878799
GO:0005381	iron ion transmembrane transporter activity	3/3063	10/18639	0.3	1.82556317335945	0.218249029907489	0.647230320878799
GO:0008140	cAMP response element binding protein binding	3/3063	10/18639	0.3	1.82556317335945	0.218249029907489	0.647230320878799
GO:0008641	ubiquitin-like modifier activating enzyme activity	3/3063	10/18639	0.3	1.82556317335945	0.218249029907489	0.647230320878799
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/3063	10/18639	0.3	1.82556317335945	0.218249029907489	0.647230320878799
GO:0031434	mitogen-activated protein kinase kinase binding	3/3063	10/18639	0.3	1.82556317335945	0.218249029907489	0.647230320878799
GO:0035374	chondroitin sulfate binding	3/3063	10/18639	0.3	1.82556317335945	0.218249029907489	0.647230320878799
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/3063	10/18639	0.3	1.82556317335945	0.218249029907489	0.647230320878799
GO:0043422	protein kinase B binding	3/3063	10/18639	0.3	1.82556317335945	0.218249029907489	0.647230320878799
GO:0070097	delta-catenin binding	3/3063	10/18639	0.3	1.82556317335945	0.218249029907489	0.647230320878799
GO:0099122	RNA polymerase II C-terminal domain binding	3/3063	10/18639	0.3	1.82556317335945	0.218249029907489	0.647230320878799
GO:1905394	retromer complex binding	3/3063	10/18639	0.3	1.82556317335945	0.218249029907489	0.647230320878799
GO:0016877	ligase activity, forming carbon-sulfur bonds	9/3063	41/18639	0.219512195121951	1.33577793172643	0.222117667836655	0.647230320878799
GO:0140318	protein transporter activity	9/3063	41/18639	0.219512195121951	1.33577793172643	0.222117667836655	0.647230320878799
GO:0001972	retinoic acid binding	5/3063	20/18639	0.25	1.52130264446621	0.222164509836376	0.647230320878799
GO:0016505	peptidase activator activity involved in apoptotic process	5/3063	20/18639	0.25	1.52130264446621	0.222164509836376	0.647230320878799
GO:0004467	long-chain fatty acid-CoA ligase activity	4/3063	15/18639	0.266666666666667	1.62272282076396	0.223561436972785	0.647230320878799
GO:0004865	protein serine/threonine phosphatase inhibitor activity	4/3063	15/18639	0.266666666666667	1.62272282076396	0.223561436972785	0.647230320878799
GO:0005523	tropomyosin binding	4/3063	15/18639	0.266666666666667	1.62272282076396	0.223561436972785	0.647230320878799
GO:0030553	cGMP binding	4/3063	15/18639	0.266666666666667	1.62272282076396	0.223561436972785	0.647230320878799
GO:0033130	acetylcholine receptor binding	4/3063	15/18639	0.266666666666667	1.62272282076396	0.223561436972785	0.647230320878799
GO:0051371	muscle alpha-actinin binding	4/3063	15/18639	0.266666666666667	1.62272282076396	0.223561436972785	0.647230320878799
GO:0061578	K63-linked deubiquitinase activity	4/3063	15/18639	0.266666666666667	1.62272282076396	0.223561436972785	0.647230320878799
GO:0004843	cysteine-type deubiquitinase activity	21/3063	108/18639	0.194444444444444	1.18323539014039	0.2324652010321	0.671508609662883
GO:0140938	histone H3 methyltransferase activity	10/3063	47/18639	0.212765957446809	1.29472565486486	0.234948950913487	0.676511145323663
GO:0002039	p53 binding	14/3063	69/18639	0.202898550724638	1.23468040710301	0.23524019008556	0.676511145323663
GO:0047499	calcium-independent phospholipase A2 activity	7/3063	31/18639	0.225806451612903	1.37407980790496	0.238521529316403	0.682919257225994
GO:0140457	protein demethylase activity	7/3063	31/18639	0.225806451612903	1.37407980790496	0.238521529316403	0.682919257225994
GO:0016209	antioxidant activity	17/3063	86/18639	0.197674418604651	1.20289046306631	0.239657104493078	0.68465917296811
GO:0046982	protein heterodimerization activity	66/3063	369/18639	0.178861788617886	1.08841164807339	0.242676337605641	0.689489088034841
GO:0016859	cis-trans isomerase activity	9/3063	42/18639	0.214285714285714	1.30397369525675	0.244457371707421	0.689489088034841
GO:0038064	collagen receptor activity	11/3063	53/18639	0.207547169811321	1.26296823314176	0.245841540607156	0.689489088034841
GO:0005112	Notch binding	6/3063	26/18639	0.230769230769231	1.40427936412265	0.24690207755493	0.689489088034841
GO:0005160	transforming growth factor beta receptor binding	6/3063	26/18639	0.230769230769231	1.40427936412265	0.24690207755493	0.689489088034841
GO:0050750	low-density lipoprotein particle receptor binding	6/3063	26/18639	0.230769230769231	1.40427936412265	0.24690207755493	0.689489088034841
GO:0052742	phosphatidylinositol kinase activity	6/3063	26/18639	0.230769230769231	1.40427936412265	0.24690207755493	0.689489088034841
GO:0033192	calmodulin-dependent protein phosphatase activity	16/3063	81/18639	0.197530864197531	1.2020169042696	0.249321805927787	0.689489088034841
GO:0140791	histone H2AXS140 phosphatase activity	16/3063	81/18639	0.197530864197531	1.2020169042696	0.249321805927787	0.689489088034841
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	16/3063	81/18639	0.197530864197531	1.2020169042696	0.249321805927787	0.689489088034841
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	16/3063	81/18639	0.197530864197531	1.2020169042696	0.249321805927787	0.689489088034841
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	16/3063	81/18639	0.197530864197531	1.2020169042696	0.249321805927787	0.689489088034841
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	16/3063	81/18639	0.197530864197531	1.2020169042696	0.249321805927787	0.689489088034841
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	16/3063	81/18639	0.197530864197531	1.2020169042696	0.249321805927787	0.689489088034841
GO:1990439	MAP kinase serine/threonine phosphatase activity	16/3063	81/18639	0.197530864197531	1.2020169042696	0.249321805927787	0.689489088034841
GO:0009975	cyclase activity	5/3063	21/18639	0.238095238095238	1.44885966139639	0.255017757993433	0.690771195107415
GO:0035613	RNA stem-loop binding	5/3063	21/18639	0.238095238095238	1.44885966139639	0.255017757993433	0.690771195107415
GO:0016879	ligase activity, forming carbon-nitrogen bonds	10/3063	48/18639	0.208333333333333	1.26775220372184	0.256289006853855	0.690771195107415
GO:0140034	methylation-dependent protein binding	15/3063	76/18639	0.197368421052632	1.20102840352595	0.259606109168671	0.690771195107415
GO:0051213	dioxygenase activity	18/3063	93/18639	0.193548387096774	1.17778269248997	0.260810040392347	0.690771195107415
GO:0000062	fatty-acyl-CoA binding	4/3063	16/18639	0.25	1.52130264446621	0.262057294062718	0.690771195107415
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	4/3063	16/18639	0.25	1.52130264446621	0.262057294062718	0.690771195107415
GO:0004708	MAP kinase kinase activity	4/3063	16/18639	0.25	1.52130264446621	0.262057294062718	0.690771195107415
GO:0005149	interleukin-1 receptor binding	4/3063	16/18639	0.25	1.52130264446621	0.262057294062718	0.690771195107415
GO:0019841	retinol binding	4/3063	16/18639	0.25	1.52130264446621	0.262057294062718	0.690771195107415
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/3063	16/18639	0.25	1.52130264446621	0.262057294062718	0.690771195107415
GO:0055102	lipase inhibitor activity	4/3063	16/18639	0.25	1.52130264446621	0.262057294062718	0.690771195107415
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	4/3063	16/18639	0.25	1.52130264446621	0.262057294062718	0.690771195107415
GO:0043425	bHLH transcription factor binding	7/3063	32/18639	0.21875	1.33113981390793	0.265323228016869	0.690771195107415
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/3063	11/18639	0.272727272727273	1.65960288487223	0.26575276642446	0.690771195107415
GO:0004016	adenylate cyclase activity	3/3063	11/18639	0.272727272727273	1.65960288487223	0.26575276642446	0.690771195107415
GO:0004143	ATP-dependent diacylglycerol kinase activity	3/3063	11/18639	0.272727272727273	1.65960288487223	0.26575276642446	0.690771195107415
GO:0005536	D-glucose binding	3/3063	11/18639	0.272727272727273	1.65960288487223	0.26575276642446	0.690771195107415
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	3/3063	11/18639	0.272727272727273	1.65960288487223	0.26575276642446	0.690771195107415
GO:0019206	nucleoside kinase activity	3/3063	11/18639	0.272727272727273	1.65960288487223	0.26575276642446	0.690771195107415
GO:0034056	estrogen response element binding	3/3063	11/18639	0.272727272727273	1.65960288487223	0.26575276642446	0.690771195107415
GO:0034713	type I transforming growth factor beta receptor binding	3/3063	11/18639	0.272727272727273	1.65960288487223	0.26575276642446	0.690771195107415
GO:0048185	activin binding	3/3063	11/18639	0.272727272727273	1.65960288487223	0.26575276642446	0.690771195107415
GO:0050998	nitric-oxide synthase binding	3/3063	11/18639	0.272727272727273	1.65960288487223	0.26575276642446	0.690771195107415
GO:0070697	activin receptor binding	3/3063	11/18639	0.272727272727273	1.65960288487223	0.26575276642446	0.690771195107415
GO:0140031	phosphorylation-dependent protein binding	3/3063	11/18639	0.272727272727273	1.65960288487223	0.26575276642446	0.690771195107415
GO:0140537	transcription regulator activator activity	3/3063	11/18639	0.272727272727273	1.65960288487223	0.26575276642446	0.690771195107415
GO:0180030	inositol phosphate kinase activity	3/3063	11/18639	0.272727272727273	1.65960288487223	0.26575276642446	0.690771195107415
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	16/3063	82/18639	0.195121951219512	1.1873581615346	0.265810548861475	0.690771195107415
GO:0033549	MAP kinase phosphatase activity	16/3063	82/18639	0.195121951219512	1.1873581615346	0.265810548861475	0.690771195107415
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	11/3063	54/18639	0.203703703703704	1.23957993252802	0.266295757558757	0.690771195107415
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	62/3063	349/18639	0.177650429799427	1.08104027457771	0.269369926398963	0.697350887304302
GO:0001671	ATPase activator activity	6/3063	27/18639	0.222222222222222	1.3522690173033	0.276779043171805	0.699375891883394
GO:0004683	calcium/calmodulin-dependent protein kinase activity	6/3063	27/18639	0.222222222222222	1.3522690173033	0.276779043171805	0.699375891883394
GO:0008320	protein transmembrane transporter activity	6/3063	27/18639	0.222222222222222	1.3522690173033	0.276779043171805	0.699375891883394
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	6/3063	27/18639	0.222222222222222	1.3522690173033	0.276779043171805	0.699375891883394
GO:0005004	GPI-linked ephrin receptor activity	10/3063	49/18639	0.204081632653061	1.24187970976833	0.27824052445014	0.699375891883394
GO:0005008	hepatocyte growth factor receptor activity	10/3063	49/18639	0.204081632653061	1.24187970976833	0.27824052445014	0.699375891883394
GO:0005009	insulin receptor activity	10/3063	49/18639	0.204081632653061	1.24187970976833	0.27824052445014	0.699375891883394
GO:0005011	macrophage colony-stimulating factor receptor activity	10/3063	49/18639	0.204081632653061	1.24187970976833	0.27824052445014	0.699375891883394
GO:0005018	platelet-derived growth factor alpha-receptor activity	10/3063	49/18639	0.204081632653061	1.24187970976833	0.27824052445014	0.699375891883394
GO:0005020	stem cell factor receptor activity	10/3063	49/18639	0.204081632653061	1.24187970976833	0.27824052445014	0.699375891883394
GO:0008288	boss receptor activity	10/3063	49/18639	0.204081632653061	1.24187970976833	0.27824052445014	0.699375891883394
GO:0035254	glutamate receptor binding	10/3063	49/18639	0.204081632653061	1.24187970976833	0.27824052445014	0.699375891883394
GO:0036332	placental growth factor receptor activity	10/3063	49/18639	0.204081632653061	1.24187970976833	0.27824052445014	0.699375891883394
GO:0038062	protein tyrosine kinase collagen receptor activity	10/3063	49/18639	0.204081632653061	1.24187970976833	0.27824052445014	0.699375891883394
GO:0060175	brain-derived neurotrophic factor receptor activity	10/3063	49/18639	0.204081632653061	1.24187970976833	0.27824052445014	0.699375891883394
GO:0043531	ADP binding	8/3063	38/18639	0.210526315789474	1.28109696376102	0.279667005155936	0.701601751812861
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	16/3063	83/18639	0.192771084337349	1.17305264151611	0.282677268535126	0.702463037939747
GO:0140313	molecular sequestering activity	11/3063	55/18639	0.2	1.21704211557297	0.287276300277833	0.702463037939747
GO:0005243	gap junction channel activity	5/3063	22/18639	0.227272727272727	1.38300240406019	0.288935368932246	0.702463037939747
GO:0032931	histone H3K56 acetyltransferase activity	5/3063	22/18639	0.227272727272727	1.38300240406019	0.288935368932246	0.702463037939747
GO:0043992	histone H3K9 acetyltransferase activity	5/3063	22/18639	0.227272727272727	1.38300240406019	0.288935368932246	0.702463037939747
GO:0043993	histone H3K18 acetyltransferase activity	5/3063	22/18639	0.227272727272727	1.38300240406019	0.288935368932246	0.702463037939747
GO:0043994	histone H3K23 acetyltransferase activity	5/3063	22/18639	0.227272727272727	1.38300240406019	0.288935368932246	0.702463037939747
GO:0043999	histone H2AK5 acetyltransferase activity	5/3063	22/18639	0.227272727272727	1.38300240406019	0.288935368932246	0.702463037939747
GO:0044012	histone H2AK9 acetyltransferase activity	5/3063	22/18639	0.227272727272727	1.38300240406019	0.288935368932246	0.702463037939747
GO:0044014	histone H2BK5 acetyltransferase activity	5/3063	22/18639	0.227272727272727	1.38300240406019	0.288935368932246	0.702463037939747
GO:0044015	histone H2BK12 acetyltransferase activity	5/3063	22/18639	0.227272727272727	1.38300240406019	0.288935368932246	0.702463037939747
GO:0044016	histone H3K4 acetyltransferase activity	5/3063	22/18639	0.227272727272727	1.38300240406019	0.288935368932246	0.702463037939747
GO:0044017	histone H3K27 acetyltransferase activity	5/3063	22/18639	0.227272727272727	1.38300240406019	0.288935368932246	0.702463037939747
GO:0044018	histone H3K36 acetyltransferase activity	5/3063	22/18639	0.227272727272727	1.38300240406019	0.288935368932246	0.702463037939747
GO:0046972	histone H4K16 acetyltransferase activity	5/3063	22/18639	0.227272727272727	1.38300240406019	0.288935368932246	0.702463037939747
GO:0140908	histone H3K122 acetyltransferase activity	5/3063	22/18639	0.227272727272727	1.38300240406019	0.288935368932246	0.702463037939747
GO:0043022	ribosome binding	21/3063	112/18639	0.1875	1.14097698334966	0.289217627031476	0.702463037939747
GO:0001046	core promoter sequence-specific DNA binding	9/3063	44/18639	0.204545454545455	1.24470216365417	0.291204141741691	0.704648828057786
GO:0016790	thiolester hydrolase activity	9/3063	44/18639	0.204545454545455	1.24470216365417	0.291204141741691	0.704648828057786
GO:0017018	myosin phosphatase activity	16/3063	84/18639	0.19047619047619	1.15908772911711	0.299884033985771	0.715257056353988
GO:0005006	epidermal growth factor receptor activity	10/3063	50/18639	0.2	1.21704211557297	0.300714940420797	0.715257056353988
GO:0005007	fibroblast growth factor receptor activity	10/3063	50/18639	0.2	1.21704211557297	0.300714940420797	0.715257056353988
GO:0005017	platelet-derived growth factor receptor activity	10/3063	50/18639	0.2	1.21704211557297	0.300714940420797	0.715257056353988
GO:0005019	platelet-derived growth factor beta-receptor activity	10/3063	50/18639	0.2	1.21704211557297	0.300714940420797	0.715257056353988
GO:0008569	minus-end-directed microtubule motor activity	4/3063	17/18639	0.235294117647059	1.43181425361526	0.301654286681289	0.715257056353988
GO:0031489	myosin V binding	4/3063	17/18639	0.235294117647059	1.43181425361526	0.301654286681289	0.715257056353988
GO:0038191	neuropilin binding	4/3063	17/18639	0.235294117647059	1.43181425361526	0.301654286681289	0.715257056353988
GO:0046965	nuclear retinoid X receptor binding	4/3063	17/18639	0.235294117647059	1.43181425361526	0.301654286681289	0.715257056353988
GO:0048038	quinone binding	4/3063	17/18639	0.235294117647059	1.43181425361526	0.301654286681289	0.715257056353988
GO:1901567	fatty acid derivative binding	4/3063	17/18639	0.235294117647059	1.43181425361526	0.301654286681289	0.715257056353988
GO:0036408	histone H3K14 acetyltransferase activity	6/3063	28/18639	0.214285714285714	1.30397369525675	0.307423684470195	0.724005718264077
GO:0046625	sphingolipid binding	6/3063	28/18639	0.214285714285714	1.30397369525675	0.307423684470195	0.724005718264077
GO:0046875	ephrin receptor binding	6/3063	28/18639	0.214285714285714	1.30397369525675	0.307423684470195	0.724005718264077
GO:0016407	acetyltransferase activity	18/3063	96/18639	0.1875	1.14097698334966	0.308738366014382	0.724005718264077
GO:0005025	transforming growth factor beta receptor activity, type I	3/3063	12/18639	0.25	1.52130264446621	0.314275419724499	0.724005718264077
GO:0005026	transforming growth factor beta receptor activity, type II	3/3063	12/18639	0.25	1.52130264446621	0.314275419724499	0.724005718264077
GO:0010853	cyclase activator activity	3/3063	12/18639	0.25	1.52130264446621	0.314275419724499	0.724005718264077
GO:0015269	calcium-activated potassium channel activity	3/3063	12/18639	0.25	1.52130264446621	0.314275419724499	0.724005718264077
GO:0016208	AMP binding	3/3063	12/18639	0.25	1.52130264446621	0.314275419724499	0.724005718264077
GO:0016273	arginine N-methyltransferase activity	3/3063	12/18639	0.25	1.52130264446621	0.314275419724499	0.724005718264077
GO:0016274	protein-arginine N-methyltransferase activity	3/3063	12/18639	0.25	1.52130264446621	0.314275419724499	0.724005718264077
GO:0016361	activin receptor activity, type I	3/3063	12/18639	0.25	1.52130264446621	0.314275419724499	0.724005718264077
GO:0016362	activin receptor activity, type II	3/3063	12/18639	0.25	1.52130264446621	0.314275419724499	0.724005718264077
GO:0017002	activin receptor activity	3/3063	12/18639	0.25	1.52130264446621	0.314275419724499	0.724005718264077
GO:0035497	cAMP response element binding	3/3063	12/18639	0.25	1.52130264446621	0.314275419724499	0.724005718264077
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/3063	12/18639	0.25	1.52130264446621	0.314275419724499	0.724005718264077
GO:0008201	heparin binding	31/3063	172/18639	0.180232558139535	1.09675306926634	0.3157458989642	0.726103600986822
GO:0061135	endopeptidase regulator activity	33/3063	184/18639	0.179347826086957	1.09136928842141	0.31930403583611	0.732986432706964
GO:0015035	protein-disulfide reductase activity	7/3063	34/18639	0.205882352941176	1.25283747191335	0.32105324733976	0.735699755829803
GO:0005283	amino acid:sodium symporter activity	5/3063	23/18639	0.217391304347826	1.32287186475323	0.323580915085206	0.736380597532125
GO:0044013	histone H2B acetyltransferase activity	5/3063	23/18639	0.217391304347826	1.32287186475323	0.323580915085206	0.736380597532125
GO:0005010	insulin-like growth factor receptor activity	10/3063	51/18639	0.196078431372549	1.19317854467938	0.32362138827549	0.736380597532125
GO:0005021	vascular endothelial growth factor receptor activity	10/3063	51/18639	0.196078431372549	1.19317854467938	0.32362138827549	0.736380597532125
GO:0004866	endopeptidase inhibitor activity	29/3063	161/18639	0.180124223602484	1.09609383079553	0.324528678718752	0.737151832396186
GO:0035064	methylated histone binding	14/3063	74/18639	0.189189189189189	1.15125605527173	0.32658083226541	0.740516327706707
GO:0004722	protein serine/threonine phosphatase activity	19/3063	103/18639	0.184466019417476	1.12251457261584	0.32865036040914	0.743908407418245
GO:0015078	proton transmembrane transporter activity	33/3063	185/18639	0.178378378378378	1.08546999497048	0.331321488454133	0.746629426490653
GO:0030331	nuclear estrogen receptor binding	8/3063	40/18639	0.2	1.21704211557297	0.331579452319673	0.746629426490653
GO:0071949	FAD binding	8/3063	40/18639	0.2	1.21704211557297	0.331579452319673	0.746629426490653
GO:0101005	deubiquitinase activity	21/3063	115/18639	0.182608695652174	1.11121236639271	0.334546743428674	0.75200541807104
GO:0010484	histone H3 acetyltransferase activity	6/3063	29/18639	0.206896551724138	1.25900908507548	0.338602321277188	0.758281472223702
GO:0016279	protein-lysine N-methyltransferase activity	13/3063	69/18639	0.188405797101449	1.1464889494528	0.341435858115365	0.758281472223702
GO:0000900	mRNA regulatory element binding translation repressor activity	4/3063	18/18639	0.222222222222222	1.3522690173033	0.341838001542697	0.758281472223702
GO:0008525	phosphatidylcholine transporter activity	4/3063	18/18639	0.222222222222222	1.3522690173033	0.341838001542697	0.758281472223702
GO:0031690	adrenergic receptor binding	4/3063	18/18639	0.222222222222222	1.3522690173033	0.341838001542697	0.758281472223702
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	4/3063	18/18639	0.222222222222222	1.3522690173033	0.341838001542697	0.758281472223702
GO:1901611	phosphatidylglycerol binding	4/3063	18/18639	0.222222222222222	1.3522690173033	0.341838001542697	0.758281472223702
GO:0042626	ATPase-coupled transmembrane transporter activity	18/3063	98/18639	0.183673469387755	1.1176917387915	0.342015930031508	0.758281472223702
GO:0003725	double-stranded RNA binding	14/3063	75/18639	0.186666666666667	1.13590597453477	0.345841542759319	0.765454745663544
GO:0004623	phospholipase A2 activity	7/3063	35/18639	0.2	1.21704211557297	0.349631925791765	0.771211917945441
GO:0010485	histone H4 acetyltransferase activity	7/3063	35/18639	0.2	1.21704211557297	0.349631925791765	0.771211917945441
GO:0017080	sodium channel regulator activity	8/3063	41/18639	0.195121951219512	1.1873581615346	0.358115642497374	0.772954876776841
GO:0001091	RNA polymerase II general transcription initiation factor binding	5/3063	24/18639	0.208333333333333	1.26775220372184	0.358630997532954	0.772954876776841
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	5/3063	24/18639	0.208333333333333	1.26775220372184	0.358630997532954	0.772954876776841
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	5/3063	24/18639	0.208333333333333	1.26775220372184	0.358630997532954	0.772954876776841
GO:0004622	lysophospholipase activity	5/3063	24/18639	0.208333333333333	1.26775220372184	0.358630997532954	0.772954876776841
GO:0004806	triacylglycerol lipase activity	5/3063	24/18639	0.208333333333333	1.26775220372184	0.358630997532954	0.772954876776841
GO:0030215	semaphorin receptor binding	5/3063	24/18639	0.208333333333333	1.26775220372184	0.358630997532954	0.772954876776841
GO:0043998	histone H2A acetyltransferase activity	5/3063	24/18639	0.208333333333333	1.26775220372184	0.358630997532954	0.772954876776841
GO:0016278	lysine N-methyltransferase activity	13/3063	70/18639	0.185714285714286	1.13011053588918	0.361677936908451	0.772954876776841
GO:0002161	aminoacyl-tRNA editing activity	3/3063	13/18639	0.230769230769231	1.40427936412265	0.362937178070236	0.772954876776841
GO:0005172	vascular endothelial growth factor receptor binding	3/3063	13/18639	0.230769230769231	1.40427936412265	0.362937178070236	0.772954876776841
GO:0031432	titin binding	3/3063	13/18639	0.230769230769231	1.40427936412265	0.362937178070236	0.772954876776841
GO:0035673	oligopeptide transmembrane transporter activity	3/3063	13/18639	0.230769230769231	1.40427936412265	0.362937178070236	0.772954876776841
GO:0045159	myosin II binding	3/3063	13/18639	0.230769230769231	1.40427936412265	0.362937178070236	0.772954876776841
GO:0046975	histone H3K36 methyltransferase activity	3/3063	13/18639	0.230769230769231	1.40427936412265	0.362937178070236	0.772954876776841
GO:0051011	microtubule minus-end binding	3/3063	13/18639	0.230769230769231	1.40427936412265	0.362937178070236	0.772954876776841
GO:0070123	transforming growth factor beta receptor activity, type III	3/3063	13/18639	0.230769230769231	1.40427936412265	0.362937178070236	0.772954876776841
GO:0070700	BMP receptor binding	3/3063	13/18639	0.230769230769231	1.40427936412265	0.362937178070236	0.772954876776841
GO:0089720	caspase binding	3/3063	13/18639	0.230769230769231	1.40427936412265	0.362937178070236	0.772954876776841
GO:0097157	pre-mRNA intronic binding	3/3063	13/18639	0.230769230769231	1.40427936412265	0.362937178070236	0.772954876776841
GO:0140666	annealing activity	3/3063	13/18639	0.230769230769231	1.40427936412265	0.362937178070236	0.772954876776841
GO:0061733	protein-lysine-acetyltransferase activity	9/3063	47/18639	0.191489361702128	1.16525308937837	0.364861956821582	0.773526549349959
GO:0001965	G-protein alpha-subunit binding	6/3063	30/18639	0.2	1.21704211557297	0.370087899840496	0.773526549349959
GO:0016769	transferase activity, transferring nitrogenous groups	6/3063	30/18639	0.2	1.21704211557297	0.370087899840496	0.773526549349959
GO:0033612	receptor serine/threonine kinase binding	6/3063	30/18639	0.2	1.21704211557297	0.370087899840496	0.773526549349959
GO:0043995	histone H4K5 acetyltransferase activity	6/3063	30/18639	0.2	1.21704211557297	0.370087899840496	0.773526549349959
GO:0043996	histone H4K8 acetyltransferase activity	6/3063	30/18639	0.2	1.21704211557297	0.370087899840496	0.773526549349959
GO:0043997	histone H4K12 acetyltransferase activity	6/3063	30/18639	0.2	1.21704211557297	0.370087899840496	0.773526549349959
GO:0098918	structural constituent of synapse	6/3063	30/18639	0.2	1.21704211557297	0.370087899840496	0.773526549349959
GO:0005003	ephrin receptor activity	10/3063	53/18639	0.188679245283019	1.14815293921978	0.370362364800559	0.773526549349959
GO:0005005	transmembrane-ephrin receptor activity	10/3063	53/18639	0.188679245283019	1.14815293921978	0.370362364800559	0.773526549349959
GO:0016860	intramolecular oxidoreductase activity	10/3063	53/18639	0.188679245283019	1.14815293921978	0.370362364800559	0.773526549349959
GO:0034212	protein N-acetyltransferase activity	10/3063	53/18639	0.188679245283019	1.14815293921978	0.370362364800559	0.773526549349959
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	11/3063	59/18639	0.186440677966102	1.13453078570361	0.374934804668873	0.781817430314354
GO:0003756	protein disulfide isomerase activity	4/3063	19/18639	0.210526315789474	1.28109696376102	0.382136952448012	0.79428145404659
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	4/3063	19/18639	0.210526315789474	1.28109696376102	0.382136952448012	0.79428145404659
GO:0016298	lipase activity	23/3063	130/18639	0.176923076923077	1.0766141791607	0.38433348118803	0.797383096249096
GO:0035198	miRNA binding	8/3063	42/18639	0.19047619047619	1.15908772911711	0.384858765036187	0.797383096249096
GO:0008139	nuclear localization sequence binding	5/3063	25/18639	0.2	1.21704211557297	0.393781626550818	0.80988270171317
GO:0042974	nuclear retinoic acid receptor binding	5/3063	25/18639	0.2	1.21704211557297	0.393781626550818	0.80988270171317
GO:0047617	fatty acyl-CoA hydrolase activity	5/3063	25/18639	0.2	1.21704211557297	0.393781626550818	0.80988270171317
GO:0051287	NAD binding	10/3063	54/18639	0.185185185185185	1.12689084775275	0.394013866446423	0.80988270171317
GO:0140463	chromatin-protein adaptor activity	10/3063	54/18639	0.185185185185185	1.12689084775275	0.394013866446423	0.80988270171317
GO:0061134	peptidase regulator activity	39/3063	226/18639	0.172566371681416	1.05010271033951	0.39581840220611	0.812304537438805
GO:0031072	heat shock protein binding	23/3063	131/18639	0.175572519083969	1.06839575031215	0.399487205996581	0.818538556362664
GO:0016878	acid-thiol ligase activity	6/3063	31/18639	0.193548387096774	1.17778269248997	0.401663828766279	0.820406277023407
GO:0070325	lipoprotein particle receptor binding	6/3063	31/18639	0.193548387096774	1.17778269248997	0.401663828766279	0.820406277023407
GO:0022829	wide pore channel activity	7/3063	37/18639	0.189189189189189	1.15125605527173	0.407366140185446	0.82517814302449
GO:0005161	platelet-derived growth factor receptor binding	3/3063	14/18639	0.214285714285714	1.30397369525675	0.410998519964395	0.82517814302449
GO:0008474	palmitoyl-(protein) hydrolase activity	3/3063	14/18639	0.214285714285714	1.30397369525675	0.410998519964395	0.82517814302449
GO:0008494	translation activator activity	3/3063	14/18639	0.214285714285714	1.30397369525675	0.410998519964395	0.82517814302449
GO:0016530	metallochaperone activity	3/3063	14/18639	0.214285714285714	1.30397369525675	0.410998519964395	0.82517814302449
GO:0019992	diacylglycerol binding	3/3063	14/18639	0.214285714285714	1.30397369525675	0.410998519964395	0.82517814302449
GO:0032454	histone H3K9 demethylase activity	3/3063	14/18639	0.214285714285714	1.30397369525675	0.410998519964395	0.82517814302449
GO:0071933	Arp2/3 complex binding	3/3063	14/18639	0.214285714285714	1.30397369525675	0.410998519964395	0.82517814302449
GO:0098599	palmitoyl hydrolase activity	3/3063	14/18639	0.214285714285714	1.30397369525675	0.410998519964395	0.82517814302449
GO:0098821	BMP receptor activity	3/3063	14/18639	0.214285714285714	1.30397369525675	0.410998519964395	0.82517814302449
GO:1901612	cardiolipin binding	3/3063	14/18639	0.214285714285714	1.30397369525675	0.410998519964395	0.82517814302449
GO:0019955	cytokine binding	25/3063	144/18639	0.173611111111111	1.0564601697682	0.415799501206551	0.833526975370782
GO:0016853	isomerase activity	31/3063	180/18639	0.172222222222222	1.04800848841006	0.41788612346632	0.836417132925643
GO:0016500	protein-hormone receptor activity	12/3063	67/18639	0.17910447761194	1.08988846170714	0.421721587641668	0.838442100829855
GO:0042054	histone methyltransferase activity	12/3063	67/18639	0.17910447761194	1.08988846170714	0.421721587641668	0.838442100829855
GO:0016004	phospholipase activator activity	4/3063	20/18639	0.2	1.21704211557297	0.422130063100922	0.838442100829855
GO:0061608	nuclear import signal receptor activity	4/3063	20/18639	0.2	1.21704211557297	0.422130063100922	0.838442100829855
GO:0140939	histone H4 methyltransferase activity	4/3063	20/18639	0.2	1.21704211557297	0.422130063100922	0.838442100829855
GO:0004620	phospholipase activity	19/3063	109/18639	0.174311926605505	1.06072477962782	0.428445604553532	0.847558475341156
GO:0004112	cyclic-nucleotide phosphodiesterase activity	5/3063	26/18639	0.192307692307692	1.17023280343555	0.428752947740316	0.847558475341156
GO:0016289	acyl-CoA hydrolase activity	5/3063	26/18639	0.192307692307692	1.17023280343555	0.428752947740316	0.847558475341156
GO:0004540	RNA nuclease activity	21/3063	121/18639	0.173553719008264	1.05611092673687	0.429333784347833	0.847558475341156
GO:0030414	peptidase inhibitor activity	29/3063	169/18639	0.171597633136095	1.04420773229633	0.430895109316804	0.849347958638139
GO:0022884	macromolecule transmembrane transporter activity	6/3063	32/18639	0.1875	1.14097698334966	0.433127044323835	0.84987258167627
GO:0047498	calcium-dependent phospholipase A2 activity	6/3063	32/18639	0.1875	1.14097698334966	0.433127044323835	0.84987258167627
GO:0070717	poly-purine tract binding	6/3063	32/18639	0.1875	1.14097698334966	0.433127044323835	0.84987258167627
GO:0005109	frizzled binding	7/3063	38/18639	0.184210526315789	1.12095984329089	0.436201428740497	0.850756771543495
GO:0005501	retinoid binding	7/3063	38/18639	0.184210526315789	1.12095984329089	0.436201428740497	0.850756771543495
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	7/3063	38/18639	0.184210526315789	1.12095984329089	0.436201428740497	0.850756771543495
GO:0019840	isoprenoid binding	7/3063	38/18639	0.184210526315789	1.12095984329089	0.436201428740497	0.850756771543495
GO:0043021	ribonucleoprotein complex binding	30/3063	177/18639	0.169491525423729	1.03139162336692	0.457623805076612	0.874271601409609
GO:0004089	carbonate dehydratase activity	3/3063	15/18639	0.2	1.21704211557297	0.457857790712298	0.874271601409609
GO:0004129	cytochrome-c oxidase activity	3/3063	15/18639	0.2	1.21704211557297	0.457857790712298	0.874271601409609
GO:0004559	alpha-mannosidase activity	3/3063	15/18639	0.2	1.21704211557297	0.457857790712298	0.874271601409609
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/3063	15/18639	0.2	1.21704211557297	0.457857790712298	0.874271601409609
GO:0017081	chloride channel regulator activity	3/3063	15/18639	0.2	1.21704211557297	0.457857790712298	0.874271601409609
GO:0047372	monoacylglycerol lipase activity	3/3063	15/18639	0.2	1.21704211557297	0.457857790712298	0.874271601409609
GO:0050700	CARD domain binding	3/3063	15/18639	0.2	1.21704211557297	0.457857790712298	0.874271601409609
GO:0005123	death receptor binding	4/3063	21/18639	0.19047619047619	1.15908772911711	0.461450605479155	0.874271601409609
GO:0019200	carbohydrate kinase activity	4/3063	21/18639	0.19047619047619	1.15908772911711	0.461450605479155	0.874271601409609
GO:0051428	peptide hormone receptor binding	4/3063	21/18639	0.19047619047619	1.15908772911711	0.461450605479155	0.874271601409609
GO:1904047	S-adenosyl-L-methionine binding	4/3063	21/18639	0.19047619047619	1.15908772911711	0.461450605479155	0.874271601409609
GO:0005385	zinc ion transmembrane transporter activity	5/3063	27/18639	0.185185185185185	1.12689084775275	0.463292471505886	0.874271601409609
GO:0016405	CoA-ligase activity	5/3063	27/18639	0.185185185185185	1.12689084775275	0.463292471505886	0.874271601409609
GO:0035255	ionotropic glutamate receptor binding	5/3063	27/18639	0.185185185185185	1.12689084775275	0.463292471505886	0.874271601409609
GO:0008081	phosphoric diester hydrolase activity	15/3063	87/18639	0.172413793103448	1.0491742375629	0.463708204589681	0.874271601409609
GO:0019239	deaminase activity	6/3063	33/18639	0.181818181818182	1.10640192324815	0.464290338228439	0.874271601409609
GO:0008080	N-acetyltransferase activity	12/3063	69/18639	0.173913043478261	1.05829749180258	0.464639857849094	0.874271601409609
GO:0005507	copper ion binding	11/3063	63/18639	0.174603174603175	1.06249708502402	0.464869744837194	0.874271601409609
GO:0004601	peroxidase activity	10/3063	57/18639	0.175438596491228	1.06758080313418	0.465034698581654	0.874271601409609
GO:0016504	peptidase activator activity	10/3063	57/18639	0.175438596491228	1.06758080313418	0.465034698581654	0.874271601409609
GO:0046915	transition metal ion transmembrane transporter activity	8/3063	45/18639	0.177777777777778	1.08181521384264	0.465057346155282	0.874271601409609
GO:0003743	translation initiation factor activity	9/3063	51/18639	0.176470588235294	1.07386069021144	0.465109795661242	0.874271601409609
GO:0005048	signal sequence binding	9/3063	51/18639	0.176470588235294	1.07386069021144	0.465109795661242	0.874271601409609
GO:0016597	amino acid binding	9/3063	51/18639	0.176470588235294	1.07386069021144	0.465109795661242	0.874271601409609
GO:0016410	N-acyltransferase activity	16/3063	94/18639	0.170212765957447	1.03578052389189	0.481713924526086	0.890442191627058
GO:0016758	hexosyltransferase activity	33/3063	197/18639	0.16751269035533	1.01934999527685	0.481790002626577	0.890442191627058
GO:0004180	carboxypeptidase activity	8/3063	46/18639	0.173913043478261	1.05829749180258	0.491388366768302	0.890442191627058
GO:0004532	RNA exonuclease activity	7/3063	40/18639	0.175	1.06491185112635	0.493080303469891	0.890442191627058
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	6/3063	34/18639	0.176470588235294	1.07386069021144	0.494984000561727	0.890442191627058
GO:0016866	intramolecular transferase activity	5/3063	28/18639	0.178571428571429	1.08664474604729	0.497176990426689	0.890442191627058
GO:0046966	nuclear thyroid hormone receptor binding	5/3063	28/18639	0.178571428571429	1.08664474604729	0.497176990426689	0.890442191627058
GO:0051393	alpha-actinin binding	5/3063	28/18639	0.178571428571429	1.08664474604729	0.497176990426689	0.890442191627058
GO:0140098	catalytic activity, acting on RNA	64/3063	387/18639	0.165374677002584	1.0063397338071	0.499408887260996	0.890442191627058
GO:0070034	telomerase RNA binding	4/3063	22/18639	0.181818181818182	1.10640192324815	0.4997873247118	0.890442191627058
GO:0003727	single-stranded RNA binding	15/3063	89/18639	0.168539325842697	1.02559728840419	0.501561866128382	0.890442191627058
GO:0005159	insulin-like growth factor receptor binding	3/3063	16/18639	0.1875	1.14097698334966	0.503042520708355	0.890442191627058
GO:0015923	mannosidase activity	3/3063	16/18639	0.1875	1.14097698334966	0.503042520708355	0.890442191627058
GO:0016675	oxidoreductase activity, acting on a heme group of donors	3/3063	16/18639	0.1875	1.14097698334966	0.503042520708355	0.890442191627058
GO:0022841	potassium ion leak channel activity	3/3063	16/18639	0.1875	1.14097698334966	0.503042520708355	0.890442191627058
GO:0030275	LRR domain binding	3/3063	16/18639	0.1875	1.14097698334966	0.503042520708355	0.890442191627058
GO:0140327	flippase activity	3/3063	16/18639	0.1875	1.14097698334966	0.503042520708355	0.890442191627058
GO:0140328	floppase activity	3/3063	16/18639	0.1875	1.14097698334966	0.503042520708355	0.890442191627058
GO:0019842	vitamin binding	25/3063	150/18639	0.166666666666667	1.01420176297747	0.503456684049688	0.890442191627058
GO:0001217	DNA-binding transcription repressor activity	46/3063	278/18639	0.165467625899281	1.00690534741648	0.504920104432556	0.890442191627058
GO:0000182	rDNA binding	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0001094	TFIID-class transcription factor complex binding	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0005337	nucleoside transmembrane transporter activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0005345	purine nucleobase transmembrane transporter activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0008401	retinoic acid 4-hydroxylase activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0015187	glycine transmembrane transporter activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0015643	toxic substance binding	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0016303	1-phosphatidylinositol-3-kinase activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0016427	tRNA (cytidine) methyltransferase activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0016868	intramolecular phosphotransferase activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0030957	Tat protein binding	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0031996	thioesterase binding	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0035256	G protein-coupled glutamate receptor binding	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0043121	neurotrophin binding	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0043208	glycosphingolipid binding	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0043295	glutathione binding	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0045322	unmethylated CpG binding	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0047429	nucleoside triphosphate diphosphatase activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0051864	histone H3K36 demethylase activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0051880	G-quadruplex DNA binding	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0140135	mechanosensitive monoatomic cation channel activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0140940	histone H2A methyltransferase activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0140999	histone H3K4 trimethyltransferase activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:1990259	histone H2AQ104 methyltransferase activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:1990757	ubiquitin ligase activator activity	2/3063	10/18639	0.2	1.21704211557297	0.507352952669542	0.890442191627058
GO:0160215	deacylase activity	11/3063	65/18639	0.169230769230769	1.02980486702328	0.509229641067532	0.89252816819539
GO:0015459	potassium channel regulator activity	10/3063	59/18639	0.169491525423729	1.03139162336692	0.511622895427318	0.895512679310704
GO:0005246	calcium channel regulator activity	9/3063	53/18639	0.169811320754717	1.0333376452978	0.514300416401747	0.89777609700278
GO:1901505	carbohydrate derivative transmembrane transporter activity	9/3063	53/18639	0.169811320754717	1.0333376452978	0.514300416401747	0.89777609700278
GO:0008238	exopeptidase activity	17/3063	102/18639	0.166666666666667	1.01420176297747	0.516078100872054	0.898250636249208
GO:0001784	phosphotyrosine residue binding	8/3063	47/18639	0.170212765957447	1.03578052389189	0.517342502141988	0.898250636249208
GO:0061749	forked DNA-dependent helicase activity	8/3063	47/18639	0.170212765957447	1.03578052389189	0.517342502141988	0.898250636249208
GO:1990518	single-stranded 3'-5' DNA helicase activity	8/3063	47/18639	0.170212765957447	1.03578052389189	0.517342502141988	0.898250636249208
GO:0008194	UDP-glycosyltransferase activity	24/3063	145/18639	0.16551724137931	1.00720726806039	0.519529088304299	0.900841213276305
GO:0042169	SH2 domain binding	7/3063	41/18639	0.170731707317073	1.03893839134278	0.520867145434821	0.901955524204222
GO:0000175	3'-5'-RNA exonuclease activity	6/3063	35/18639	0.171428571428571	1.0431789562054	0.525056843617581	0.907998301562669
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	44/3063	268/18639	0.164179104477612	0.999064423231541	0.528637780476809	0.910245469282124
GO:0005416	amino acid:monoatomic cation symporter activity	5/3063	29/18639	0.172413793103448	1.0491742375629	0.530213379832835	0.910245469282124
GO:0051861	glycolipid binding	5/3063	29/18639	0.172413793103448	1.0491742375629	0.530213379832835	0.910245469282124
GO:0046906	tetrapyrrole binding	25/3063	152/18639	0.164473684210526	1.0008570029383	0.53228124668957	0.910245469282124
GO:0005253	monoatomic anion channel activity	17/3063	103/18639	0.16504854368932	1.00435514391944	0.533511908146199	0.910245469282124
GO:0004714	transmembrane receptor protein tyrosine kinase activity	10/3063	60/18639	0.166666666666667	1.01420176297747	0.534468492684653	0.910245469282124
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	10/3063	60/18639	0.166666666666667	1.01420176297747	0.534468492684653	0.910245469282124
GO:0000295	adenine nucleotide transmembrane transporter activity	4/3063	23/18639	0.173913043478261	1.05829749180258	0.536883410948978	0.910245469282124
GO:0004602	glutathione peroxidase activity	4/3063	23/18639	0.173913043478261	1.05829749180258	0.536883410948978	0.910245469282124
GO:0005212	structural constituent of eye lens	4/3063	23/18639	0.173913043478261	1.05829749180258	0.536883410948978	0.910245469282124
GO:0008171	O-methyltransferase activity	4/3063	23/18639	0.173913043478261	1.05829749180258	0.536883410948978	0.910245469282124
GO:0016849	phosphorus-oxygen lyase activity	4/3063	23/18639	0.173913043478261	1.05829749180258	0.536883410948978	0.910245469282124
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/3063	23/18639	0.173913043478261	1.05829749180258	0.536883410948978	0.910245469282124
GO:0070577	lysine-acetylated histone binding	4/3063	23/18639	0.173913043478261	1.05829749180258	0.536883410948978	0.910245469282124
GO:0099186	structural constituent of postsynapse	4/3063	23/18639	0.173913043478261	1.05829749180258	0.536883410948978	0.910245469282124
GO:0009378	four-way junction helicase activity	8/3063	48/18639	0.166666666666667	1.01420176297747	0.542827551976789	0.910976915081707
GO:0036121	double-stranded DNA helicase activity	8/3063	48/18639	0.166666666666667	1.01420176297747	0.542827551976789	0.910976915081707
GO:0043138	3'-5' DNA helicase activity	8/3063	48/18639	0.166666666666667	1.01420176297747	0.542827551976789	0.910976915081707
GO:0016835	carbon-oxygen lyase activity	13/3063	79/18639	0.164556962025316	1.00136376597776	0.544993689578582	0.910976915081707
GO:0004550	nucleoside diphosphate kinase activity	3/3063	17/18639	0.176470588235294	1.07386069021144	0.546197142285584	0.910976915081707
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/3063	17/18639	0.176470588235294	1.07386069021144	0.546197142285584	0.910976915081707
GO:0008429	phosphatidylethanolamine binding	3/3063	17/18639	0.176470588235294	1.07386069021144	0.546197142285584	0.910976915081707
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/3063	17/18639	0.176470588235294	1.07386069021144	0.546197142285584	0.910976915081707
GO:0019198	transmembrane receptor protein phosphatase activity	3/3063	17/18639	0.176470588235294	1.07386069021144	0.546197142285584	0.910976915081707
GO:0032183	SUMO binding	3/3063	17/18639	0.176470588235294	1.07386069021144	0.546197142285584	0.910976915081707
GO:0070403	NAD+ binding	3/3063	17/18639	0.176470588235294	1.07386069021144	0.546197142285584	0.910976915081707
GO:1990226	histone methyltransferase binding	3/3063	17/18639	0.176470588235294	1.07386069021144	0.546197142285584	0.910976915081707
GO:0004402	histone acetyltransferase activity	7/3063	42/18639	0.166666666666667	1.01420176297747	0.548068821514547	0.910976915081707
GO:0008307	structural constituent of muscle	7/3063	42/18639	0.166666666666667	1.01420176297747	0.548068821514547	0.910976915081707
GO:0042056	chemoattractant activity	7/3063	42/18639	0.166666666666667	1.01420176297747	0.548068821514547	0.910976915081707
GO:0004521	RNA endonuclease activity	12/3063	73/18639	0.164383561643836	1.00030858814217	0.548552791579656	0.910976915081707
GO:0008170	N-methyltransferase activity	16/3063	98/18639	0.163265306122449	0.993503767814667	0.553797340211169	0.914159952489015
GO:0004869	cysteine-type endopeptidase inhibitor activity	6/3063	36/18639	0.166666666666667	1.01420176297747	0.554376680184319	0.914159952489015
GO:0004518	nuclease activity	34/3063	209/18639	0.162679425837321	0.989938562906242	0.555076402005425	0.914159952489015
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	10/3063	61/18639	0.163934426229508	0.997575504568006	0.556929066008574	0.914159952489015
GO:0016836	hydro-lyase activity	10/3063	61/18639	0.163934426229508	0.997575504568006	0.556929066008574	0.914159952489015
GO:0003953	NAD+ nucleosidase activity	2/3063	11/18639	0.181818181818182	1.10640192324815	0.561041882946226	0.914159952489015
GO:0005225	volume-sensitive anion channel activity	2/3063	11/18639	0.181818181818182	1.10640192324815	0.561041882946226	0.914159952489015
GO:0008172	S-methyltransferase activity	2/3063	11/18639	0.181818181818182	1.10640192324815	0.561041882946226	0.914159952489015
GO:0010854	adenylate cyclase regulator activity	2/3063	11/18639	0.181818181818182	1.10640192324815	0.561041882946226	0.914159952489015
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	2/3063	11/18639	0.181818181818182	1.10640192324815	0.561041882946226	0.914159952489015
GO:0015205	nucleobase transmembrane transporter activity	2/3063	11/18639	0.181818181818182	1.10640192324815	0.561041882946226	0.914159952489015
GO:0016176	superoxide-generating NADPH oxidase activator activity	2/3063	11/18639	0.181818181818182	1.10640192324815	0.561041882946226	0.914159952489015
GO:0050786	RAGE receptor binding	2/3063	11/18639	0.181818181818182	1.10640192324815	0.561041882946226	0.914159952489015
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/3063	11/18639	0.181818181818182	1.10640192324815	0.561041882946226	0.914159952489015
GO:1900750	oligopeptide binding	2/3063	11/18639	0.181818181818182	1.10640192324815	0.561041882946226	0.914159952489015
GO:0035925	mRNA 3'-UTR AU-rich region binding	5/3063	30/18639	0.166666666666667	1.01420176297747	0.562238475831302	0.914960229803261
GO:0017171	serine hydrolase activity	32/3063	198/18639	0.161616161616162	0.98346837622058	0.571259512539844	0.925766581147454
GO:0005540	hyaluronic acid binding	4/3063	24/18639	0.166666666666667	1.01420176297747	0.572533893632183	0.925766581147454
GO:0015295	solute:proton symporter activity	4/3063	24/18639	0.166666666666667	1.01420176297747	0.572533893632183	0.925766581147454
GO:0060229	lipase activator activity	4/3063	24/18639	0.166666666666667	1.01420176297747	0.572533893632183	0.925766581147454
GO:0140033	acetylation-dependent protein binding	4/3063	24/18639	0.166666666666667	1.01420176297747	0.572533893632183	0.925766581147454
GO:0030145	manganese ion binding	11/3063	68/18639	0.161764705882353	0.984372299360489	0.573592098539032	0.925766581147454
GO:0004712	protein serine/threonine/tyrosine kinase activity	7/3063	43/18639	0.162790697674419	0.990615675466369	0.574589127080725	0.925766581147454
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	7/3063	43/18639	0.162790697674419	0.990615675466369	0.574589127080725	0.925766581147454
GO:0019213	deacetylase activity	6/3063	37/18639	0.162162162162162	0.986790904518623	0.582830333087327	0.935415791957134
GO:0042805	actinin binding	6/3063	37/18639	0.162162162162162	0.986790904518623	0.582830333087327	0.935415791957134
GO:0015101	organic cation transmembrane transporter activity	13/3063	81/18639	0.160493827160494	0.976638734719048	0.583744122726499	0.935415791957134
GO:0008409	5'-3' exonuclease activity	3/3063	18/18639	0.166666666666667	1.01420176297747	0.587068970434161	0.935415791957134
GO:0015172	acidic amino acid transmembrane transporter activity	3/3063	18/18639	0.166666666666667	1.01420176297747	0.587068970434161	0.935415791957134
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/3063	18/18639	0.166666666666667	1.01420176297747	0.587068970434161	0.935415791957134
GO:0022851	GABA-gated chloride ion channel activity	3/3063	18/18639	0.166666666666667	1.01420176297747	0.587068970434161	0.935415791957134
GO:0035615	clathrin adaptor activity	3/3063	18/18639	0.166666666666667	1.01420176297747	0.587068970434161	0.935415791957134
GO:0070628	proteasome binding	3/3063	18/18639	0.166666666666667	1.01420176297747	0.587068970434161	0.935415791957134
GO:0031406	carboxylic acid binding	30/3063	187/18639	0.160427807486631	0.976236991101311	0.588323858538487	0.936265085306033
GO:0000030	mannosyltransferase activity	4/3063	25/18639	0.16	0.973633692458374	0.606581944504824	0.942479217548777
GO:0015296	monoatomic anion:monoatomic cation symporter activity	4/3063	25/18639	0.16	0.973633692458374	0.606581944504824	0.942479217548777
GO:0015645	fatty acid ligase activity	4/3063	25/18639	0.16	0.973633692458374	0.606581944504824	0.942479217548777
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	4/3063	25/18639	0.16	0.973633692458374	0.606581944504824	0.942479217548777
GO:0120515	fatty acid-CoA ligase activity	4/3063	25/18639	0.16	0.973633692458374	0.606581944504824	0.942479217548777
GO:0004867	serine-type endopeptidase inhibitor activity	15/3063	95/18639	0.157894736842105	0.960822722820764	0.610244638839754	0.942479217548777
GO:0042162	telomeric DNA binding	6/3063	38/18639	0.157894736842105	0.960822722820764	0.610323252652357	0.942479217548777
GO:0000340	RNA 7-methylguanosine cap binding	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:0004000	adenosine deaminase activity	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:0004300	enoyl-CoA hydratase activity	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:0008504	monoamine transmembrane transporter activity	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:0016801	hydrolase activity, acting on ether bonds	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:0016803	ether hydrolase activity	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:0016840	carbon-nitrogen lyase activity	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:0017166	vinculin binding	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:0035259	nuclear glucocorticoid receptor binding	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:0036009	protein-glutamine N-methyltransferase activity	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:0042301	phosphate ion binding	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:0043047	single-stranded telomeric DNA binding	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:0070410	co-SMAD binding	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:0070679	inositol 1,4,5 trisphosphate binding	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:0097371	MDM2/MDM4 family protein binding	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:1990247	N6-methyladenosine-containing RNA reader activity	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:1990459	transferrin receptor binding	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:1990817	poly(A) RNA polymerase activity	2/3063	12/18639	0.166666666666667	1.01420176297747	0.610395175590572	0.942479217548777
GO:0043177	organic acid binding	30/3063	189/18639	0.158730158730159	0.965906440930927	0.613186080719157	0.945662719016345
GO:0005272	sodium channel activity	8/3063	51/18639	0.156862745098039	0.954542835743504	0.61568969352576	0.948396119362127
GO:0005254	chloride channel activity	13/3063	83/18639	0.156626506024096	0.953105271231842	0.621036422032772	0.952189389409758
GO:0004890	GABA-A receptor activity	3/3063	19/18639	0.157894736842105	0.960822722820764	0.625493723806564	0.952189389409758
GO:0005229	intracellularly calcium-gated chloride channel activity	3/3063	19/18639	0.157894736842105	0.960822722820764	0.625493723806564	0.952189389409758
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/3063	19/18639	0.157894736842105	0.960822722820764	0.625493723806564	0.952189389409758
GO:0008381	mechanosensitive monoatomic ion channel activity	3/3063	19/18639	0.157894736842105	0.960822722820764	0.625493723806564	0.952189389409758
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/3063	19/18639	0.157894736842105	0.960822722820764	0.625493723806564	0.952189389409758
GO:0030506	ankyrin binding	3/3063	19/18639	0.157894736842105	0.960822722820764	0.625493723806564	0.952189389409758
GO:0046624	sphingolipid transporter activity	3/3063	19/18639	0.157894736842105	0.960822722820764	0.625493723806564	0.952189389409758
GO:0070003	threonine-type peptidase activity	3/3063	19/18639	0.157894736842105	0.960822722820764	0.625493723806564	0.952189389409758
GO:0141147	intracellularly calcium-gated channel activity	3/3063	19/18639	0.157894736842105	0.960822722820764	0.625493723806564	0.952189389409758
GO:0008408	3'-5' exonuclease activity	9/3063	58/18639	0.155172413793103	0.944256813806613	0.629409848087702	0.95702763536899
GO:0051087	protein-folding chaperone binding	21/3063	134/18639	0.156716417910448	0.953652403993743	0.630310493241925	0.957274835755008
GO:0000217	DNA secondary structure binding	6/3063	39/18639	0.153846153846154	0.936186242748437	0.636778815949403	0.962667672074884
GO:0004529	DNA exonuclease activity	4/3063	26/18639	0.153846153846154	0.936186242748437	0.638914489371098	0.962667672074884
GO:0008143	poly(A) binding	4/3063	26/18639	0.153846153846154	0.936186242748437	0.638914489371098	0.962667672074884
GO:0015216	purine nucleotide transmembrane transporter activity	4/3063	26/18639	0.153846153846154	0.936186242748437	0.638914489371098	0.962667672074884
GO:0030247	polysaccharide binding	4/3063	26/18639	0.153846153846154	0.936186242748437	0.638914489371098	0.962667672074884
GO:0070006	metalloaminopeptidase activity	4/3063	26/18639	0.153846153846154	0.936186242748437	0.638914489371098	0.962667672074884
GO:0004527	exonuclease activity	13/3063	84/18639	0.154761904761905	0.941758779907654	0.639056951161507	0.962667672074884
GO:0009055	electron transfer activity	18/3063	116/18639	0.155172413793103	0.944256813806613	0.643780433943067	0.968658031118513
GO:0016757	glycosyltransferase activity	42/3063	267/18639	0.157303370786517	0.957224135843907	0.647978269967464	0.973844514655621
GO:0004535	poly(A)-specific ribonuclease activity	2/3063	13/18639	0.153846153846154	0.936186242748437	0.655387538776088	0.974792483469732
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/3063	13/18639	0.153846153846154	0.936186242748437	0.655387538776088	0.974792483469732
GO:0005338	nucleotide-sugar transmembrane transporter activity	2/3063	13/18639	0.153846153846154	0.936186242748437	0.655387538776088	0.974792483469732
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/3063	13/18639	0.153846153846154	0.936186242748437	0.655387538776088	0.974792483469732
GO:0035325	Toll-like receptor binding	2/3063	13/18639	0.153846153846154	0.936186242748437	0.655387538776088	0.974792483469732
GO:0046974	histone H3K9 methyltransferase activity	2/3063	13/18639	0.153846153846154	0.936186242748437	0.655387538776088	0.974792483469732
GO:0140333	glycerophospholipid flippase activity	2/3063	13/18639	0.153846153846154	0.936186242748437	0.655387538776088	0.974792483469732
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/3063	13/18639	0.153846153846154	0.936186242748437	0.655387538776088	0.974792483469732
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/3063	13/18639	0.153846153846154	0.936186242748437	0.655387538776088	0.974792483469732
GO:0004175	endopeptidase activity	64/3063	405/18639	0.158024691358025	0.961613523415678	0.656144112492731	0.974792483469732
GO:0016779	nucleotidyltransferase activity	21/3063	136/18639	0.154411764705882	0.939628103935012	0.658377665553604	0.974792483469732
GO:0000339	RNA cap binding	3/3063	20/18639	0.15	0.912781586679726	0.661381428636972	0.974792483469732
GO:0010851	cyclase regulator activity	3/3063	20/18639	0.15	0.912781586679726	0.661381428636972	0.974792483469732
GO:0043024	ribosomal small subunit binding	3/3063	20/18639	0.15	0.912781586679726	0.661381428636972	0.974792483469732
GO:0052745	inositol phosphate phosphatase activity	3/3063	20/18639	0.15	0.912781586679726	0.661381428636972	0.974792483469732
GO:0008235	metalloexopeptidase activity	10/3063	66/18639	0.151515151515152	0.922001602706794	0.661651293571	0.974792483469732
GO:0004177	aminopeptidase activity	6/3063	40/18639	0.15	0.912781586679726	0.6621373769752	0.974792483469732
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	6/3063	40/18639	0.15	0.912781586679726	0.6621373769752	0.974792483469732
GO:0033293	monocarboxylic acid binding	12/3063	79/18639	0.151898734177215	0.924335783979469	0.663860733789854	0.97622150989279
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	28/3063	181/18639	0.154696132596685	0.94135854243213	0.66798664138091	0.97779990017205
GO:0004364	glutathione transferase activity	4/3063	27/18639	0.148148148148148	0.901512678202198	0.669457448999831	0.97779990017205
GO:0005104	fibroblast growth factor receptor binding	4/3063	27/18639	0.148148148148148	0.901512678202198	0.669457448999831	0.97779990017205
GO:0008266	poly(U) RNA binding	4/3063	27/18639	0.148148148148148	0.901512678202198	0.669457448999831	0.97779990017205
GO:0015252	proton channel activity	4/3063	27/18639	0.148148148148148	0.901512678202198	0.669457448999831	0.97779990017205
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/3063	27/18639	0.148148148148148	0.901512678202198	0.669457448999831	0.97779990017205
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	9/3063	60/18639	0.15	0.912781586679726	0.671107324310438	0.979107086198693
GO:0008236	serine-type peptidase activity	30/3063	194/18639	0.154639175257732	0.941011945030645	0.672387860498446	0.97987309558032
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	5/3063	34/18639	0.147058823529412	0.894883908509535	0.67794843648526	0.986867701595267
GO:0000049	tRNA binding	12/3063	80/18639	0.15	0.912781586679726	0.681389026658825	0.990764089211318
GO:0004252	serine-type endopeptidase activity	27/3063	176/18639	0.153409090909091	0.933526622740629	0.683594186767348	0.992160876218733
GO:0015175	neutral L-amino acid transmembrane transporter activity	6/3063	41/18639	0.146341463414634	0.890518621150952	0.686355130953551	0.992160876218733
GO:0048029	monosaccharide binding	11/3063	74/18639	0.148648648648649	0.904558329142071	0.689858272096308	0.992160876218733
GO:0015026	coreceptor activity	9/3063	61/18639	0.147540983606557	0.897817954111206	0.690868945939606	0.992160876218733
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	7/3063	48/18639	0.145833333333333	0.887426542605289	0.694507695342954	0.992160876218733
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/3063	21/18639	0.142857142857143	0.869315796837834	0.694703232496608	0.992160876218733
GO:0008373	sialyltransferase activity	3/3063	21/18639	0.142857142857143	0.869315796837834	0.694703232496608	0.992160876218733
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	3/3063	21/18639	0.142857142857143	0.869315796837834	0.694703232496608	0.992160876218733
GO:0140312	cargo adaptor activity	3/3063	21/18639	0.142857142857143	0.869315796837834	0.694703232496608	0.992160876218733
GO:0004705	JUN kinase activity	2/3063	14/18639	0.142857142857143	0.869315796837834	0.69611904191137	0.992160876218733
GO:0005313	L-glutamate transmembrane transporter activity	2/3063	14/18639	0.142857142857143	0.869315796837834	0.69611904191137	0.992160876218733
GO:0005347	ATP transmembrane transporter activity	2/3063	14/18639	0.142857142857143	0.869315796837834	0.69611904191137	0.992160876218733
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	2/3063	14/18639	0.142857142857143	0.869315796837834	0.69611904191137	0.992160876218733
GO:0032036	myosin heavy chain binding	2/3063	14/18639	0.142857142857143	0.869315796837834	0.69611904191137	0.992160876218733
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/3063	14/18639	0.142857142857143	0.869315796837834	0.69611904191137	0.992160876218733
GO:0042813	Wnt receptor activity	2/3063	14/18639	0.142857142857143	0.869315796837834	0.69611904191137	0.992160876218733
GO:0046030	inositol trisphosphate phosphatase activity	2/3063	14/18639	0.142857142857143	0.869315796837834	0.69611904191137	0.992160876218733
GO:0098847	sequence-specific single stranded DNA binding	2/3063	14/18639	0.142857142857143	0.869315796837834	0.69611904191137	0.992160876218733
GO:0051537	2 iron, 2 sulfur cluster binding	4/3063	28/18639	0.142857142857143	0.869315796837834	0.698170858762021	0.993397717970642
GO:0042393	histone binding	38/3063	247/18639	0.153846153846154	0.936186242748437	0.698617095420135	0.993397717970642
GO:1990841	promoter-specific chromatin binding	10/3063	68/18639	0.147058823529412	0.894883908509535	0.699284592526751	0.993397717970642
GO:0005343	organic acid:sodium symporter activity	5/3063	35/18639	0.142857142857143	0.869315796837834	0.703430368629874	0.99819386007981
GO:0060590	ATPase regulator activity	7/3063	49/18639	0.142857142857143	0.869315796837834	0.715632173380655	1
GO:0004629	phospholipase C activity	4/3063	29/18639	0.137931034482759	0.839339390050322	0.725044055390691	1
GO:0004407	histone deacetylase activity	3/3063	22/18639	0.136363636363636	0.829801442436114	0.72547942846263	1
GO:0008970	phospholipase A1 activity	3/3063	22/18639	0.136363636363636	0.829801442436114	0.72547942846263	1
GO:0015377	chloride:monoatomic cation symporter activity	3/3063	22/18639	0.136363636363636	0.829801442436114	0.72547942846263	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/3063	22/18639	0.136363636363636	0.829801442436114	0.72547942846263	1
GO:0033558	protein lysine deacetylase activity	3/3063	22/18639	0.136363636363636	0.829801442436114	0.72547942846263	1
GO:0033691	sialic acid binding	3/3063	22/18639	0.136363636363636	0.829801442436114	0.72547942846263	1
GO:0061133	endopeptidase activator activity	3/3063	22/18639	0.136363636363636	0.829801442436114	0.72547942846263	1
GO:0140517	protein-RNA adaptor activity	3/3063	22/18639	0.136363636363636	0.829801442436114	0.72547942846263	1
GO:0008135	translation factor activity, RNA binding	12/3063	83/18639	0.144578313253012	0.879789481137085	0.730636205222812	1
GO:0005041	low-density lipoprotein particle receptor activity	2/3063	15/18639	0.133333333333333	0.811361410381978	0.732774619018919	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	2/3063	15/18639	0.133333333333333	0.811361410381978	0.732774619018919	1
GO:0008242	omega peptidase activity	2/3063	15/18639	0.133333333333333	0.811361410381978	0.732774619018919	1
GO:0010181	FMN binding	2/3063	15/18639	0.133333333333333	0.811361410381978	0.732774619018919	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/3063	15/18639	0.133333333333333	0.811361410381978	0.732774619018919	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/3063	15/18639	0.133333333333333	0.811361410381978	0.732774619018919	1
GO:0031386	protein tag activity	2/3063	15/18639	0.133333333333333	0.811361410381978	0.732774619018919	1
GO:0140776	protein-containing complex destabilizing activity	2/3063	15/18639	0.133333333333333	0.811361410381978	0.732774619018919	1
GO:0141047	molecular tag activity	2/3063	15/18639	0.133333333333333	0.811361410381978	0.732774619018919	1
GO:0141050	histone H3K deacetylase activity	2/3063	15/18639	0.133333333333333	0.811361410381978	0.732774619018919	1
GO:0141051	histone H4K deacetylase activity	2/3063	15/18639	0.133333333333333	0.811361410381978	0.732774619018919	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	10/3063	70/18639	0.142857142857143	0.869315796837834	0.734192260233628	1
GO:0020037	heme binding	21/3063	142/18639	0.147887323943662	0.899925507994096	0.735484784287907	1
GO:0015605	organophosphate ester transmembrane transporter activity	7/3063	50/18639	0.14	0.851929480901077	0.735747056913992	1
GO:0032813	tumor necrosis factor receptor superfamily binding	7/3063	50/18639	0.14	0.851929480901077	0.735747056913992	1
GO:0015932	nucleobase-containing compound transmembrane transporter activity	8/3063	57/18639	0.140350877192982	0.854064642507346	0.740575231610717	1
GO:0180051	translation factor activity	12/3063	84/18639	0.142857142857143	0.869315796837834	0.745899414233029	1
GO:0023023	MHC protein complex binding	5/3063	37/18639	0.135135135135135	0.822325753765519	0.750071435032618	1
GO:0008187	poly-pyrimidine tract binding	4/3063	30/18639	0.133333333333333	0.811361410381978	0.750091067630597	1
GO:0015215	nucleotide transmembrane transporter activity	4/3063	30/18639	0.133333333333333	0.811361410381978	0.750091067630597	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	13/3063	91/18639	0.142857142857143	0.869315796837834	0.751505277470601	1
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	3/3063	23/18639	0.130434782608696	0.793723118851935	0.753768831089678	1
GO:0016917	GABA receptor activity	3/3063	23/18639	0.130434782608696	0.793723118851935	0.753768831089678	1
GO:0140102	catalytic activity, acting on a rRNA	3/3063	23/18639	0.130434782608696	0.793723118851935	0.753768831089678	1
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	3/3063	23/18639	0.130434782608696	0.793723118851935	0.753768831089678	1
GO:0016830	carbon-carbon lyase activity	7/3063	51/18639	0.137254901960784	0.835224981275566	0.754847091998484	1
GO:0030544	Hsp70 protein binding	7/3063	51/18639	0.137254901960784	0.835224981275566	0.754847091998484	1
GO:0017116	single-stranded DNA helicase activity	8/3063	58/18639	0.137931034482759	0.839339390050322	0.7583616929744	1
GO:0022804	active transmembrane transporter activity	70/3063	457/18639	0.153172866520788	0.932089147594176	0.760851533940198	1
GO:0038024	cargo receptor activity	9/3063	65/18639	0.138461538461538	0.842567618473593	0.762226865234323	1
GO:0004707	MAP kinase activity	2/3063	16/18639	0.125	0.760651322233105	0.765593490206143	1
GO:0008296	3'-5'-DNA exonuclease activity	2/3063	16/18639	0.125	0.760651322233105	0.765593490206143	1
GO:0015378	sodium:chloride symporter activity	2/3063	16/18639	0.125	0.760651322233105	0.765593490206143	1
GO:0017070	U6 snRNA binding	2/3063	16/18639	0.125	0.760651322233105	0.765593490206143	1
GO:0022858	alanine transmembrane transporter activity	2/3063	16/18639	0.125	0.760651322233105	0.765593490206143	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/3063	16/18639	0.125	0.760651322233105	0.765593490206143	1
GO:0097027	ubiquitin-protein transferase activator activity	2/3063	16/18639	0.125	0.760651322233105	0.765593490206143	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	2/3063	16/18639	0.125	0.760651322233105	0.765593490206143	1
GO:0030246	carbohydrate binding	42/3063	280/18639	0.15	0.912781586679726	0.765811741101444	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/3063	31/18639	0.129032258064516	0.785188461659979	0.773346304960834	1
GO:0008327	methyl-CpG binding	4/3063	31/18639	0.129032258064516	0.785188461659979	0.773346304960834	1
GO:0050660	flavin adenine dinucleotide binding	12/3063	86/18639	0.13953488372093	0.849099150399745	0.77465944303861	1
GO:0004519	endonuclease activity	18/3063	127/18639	0.141732283464567	0.86247079056352	0.788336181914868	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	5/3063	39/18639	0.128205128205128	0.780155202290364	0.791019900017361	1
GO:0042562	hormone binding	13/3063	94/18639	0.138297872340426	0.841571675662159	0.791723354580737	1
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	9/3063	67/18639	0.134328358208955	0.817416346280351	0.793206552237325	1
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	24/3063	167/18639	0.143712574850299	0.874521280651234	0.793889932978365	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/3063	17/18639	0.117647058823529	0.715907126807628	0.794846336595551	1
GO:0015278	intracellularly gated calcium channel activity	2/3063	17/18639	0.117647058823529	0.715907126807628	0.794846336595551	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/3063	17/18639	0.117647058823529	0.715907126807628	0.794846336595551	1
GO:0016018	cyclosporin A binding	2/3063	17/18639	0.117647058823529	0.715907126807628	0.794846336595551	1
GO:0016805	dipeptidase activity	2/3063	17/18639	0.117647058823529	0.715907126807628	0.794846336595551	1
GO:0030169	low-density lipoprotein particle binding	2/3063	17/18639	0.117647058823529	0.715907126807628	0.794846336595551	1
GO:0030548	acetylcholine receptor regulator activity	2/3063	17/18639	0.117647058823529	0.715907126807628	0.794846336595551	1
GO:0036041	long-chain fatty acid binding	2/3063	17/18639	0.117647058823529	0.715907126807628	0.794846336595551	1
GO:0045236	CXCR chemokine receptor binding	2/3063	17/18639	0.117647058823529	0.715907126807628	0.794846336595551	1
GO:0070492	oligosaccharide binding	2/3063	17/18639	0.117647058823529	0.715907126807628	0.794846336595551	1
GO:0015108	chloride transmembrane transporter activity	17/3063	121/18639	0.140495867768595	0.854946940691754	0.795230181752967	1
GO:0003678	DNA helicase activity	10/3063	74/18639	0.135135135135135	0.822325753765519	0.795562000605636	1
GO:0015271	outward rectifier potassium channel activity	3/3063	25/18639	0.12	0.730225269343781	0.803261026250193	1
GO:0005504	fatty acid binding	6/3063	47/18639	0.127659574468085	0.776835392918916	0.806916764626248	1
GO:0099095	ligand-gated monoatomic anion channel activity	6/3063	47/18639	0.127659574468085	0.776835392918916	0.806916764626248	1
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	5/3063	40/18639	0.125	0.760651322233105	0.809431689023384	1
GO:0008509	monoatomic anion transmembrane transporter activity	21/3063	149/18639	0.140939597315436	0.857647128423903	0.8104652632088	1
GO:0140416	transcription regulator inhibitor activity	4/3063	33/18639	0.121212121212121	0.737601282165435	0.81469766659233	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	18/3063	130/18639	0.138461538461538	0.842567618473593	0.81961103725073	1
GO:0015179	L-amino acid transmembrane transporter activity	8/3063	62/18639	0.129032258064516	0.785188461659979	0.820752072916261	1
GO:0000400	four-way junction DNA binding	2/3063	18/18639	0.111111111111111	0.676134508651649	0.820818507365724	1
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/3063	18/18639	0.111111111111111	0.676134508651649	0.820818507365724	1
GO:0015280	ligand-gated sodium channel activity	2/3063	18/18639	0.111111111111111	0.676134508651649	0.820818507365724	1
GO:0015373	monoatomic anion:sodium symporter activity	2/3063	18/18639	0.111111111111111	0.676134508651649	0.820818507365724	1
GO:0030228	lipoprotein particle receptor activity	2/3063	18/18639	0.111111111111111	0.676134508651649	0.820818507365724	1
GO:0099602	neurotransmitter receptor regulator activity	2/3063	18/18639	0.111111111111111	0.676134508651649	0.820818507365724	1
GO:0004222	metalloendopeptidase activity	15/3063	110/18639	0.136363636363636	0.829801442436114	0.821038264311407	1
GO:0051536	iron-sulfur cluster binding	10/3063	76/18639	0.131578947368421	0.800685602350637	0.822051176806234	1
GO:0004435	phosphatidylinositol phospholipase C activity	3/3063	26/18639	0.115384615384615	0.702139682061327	0.824697531060509	1
GO:0008198	ferrous iron binding	3/3063	26/18639	0.115384615384615	0.702139682061327	0.824697531060509	1
GO:0051139	metal cation:proton antiporter activity	3/3063	26/18639	0.115384615384615	0.702139682061327	0.824697531060509	1
GO:0008237	metallopeptidase activity	26/3063	184/18639	0.141304347826087	0.859866712089597	0.827747744108404	1
GO:0016831	carboxy-lyase activity	4/3063	34/18639	0.117647058823529	0.715907126807628	0.832930897273273	1
GO:0051427	hormone receptor binding	4/3063	34/18639	0.117647058823529	0.715907126807628	0.832930897273273	1
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0004935	adrenergic receptor activity	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0004955	prostaglandin receptor activity	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0004983	neuropeptide Y receptor activity	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0005031	tumor necrosis factor receptor activity	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0005131	growth hormone receptor binding	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0008190	eukaryotic initiation factor 4E binding	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0008239	dipeptidyl-peptidase activity	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0008519	ammonium channel activity	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0015279	store-operated calcium channel activity	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0016783	sulfurtransferase activity	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0031720	haptoglobin binding	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0032052	bile acid binding	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0042166	acetylcholine binding	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0042975	peroxisome proliferator activated receptor binding	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0051378	serotonin binding	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0098505	G-rich strand telomeric DNA binding	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0141109	transporter activator activity	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:1990763	arrestin family protein binding	1/3063	10/18639	0.1	0.608521057786484	0.833992757412965	1
GO:0051540	metal cluster binding	10/3063	77/18639	0.12987012987013	0.790287088034395	0.834278679891383	1
GO:0170055	lipid transmembrane transporter activity	7/3063	56/18639	0.125	0.760651322233105	0.835444119119888	1
GO:0008301	DNA binding, bending	2/3063	19/18639	0.105263157894737	0.640548481880509	0.843797893666802	1
GO:0034987	immunoglobulin receptor binding	2/3063	19/18639	0.105263157894737	0.640548481880509	0.843797893666802	1
GO:0042834	peptidoglycan binding	2/3063	19/18639	0.105263157894737	0.640548481880509	0.843797893666802	1
GO:0023026	MHC class II protein complex binding	3/3063	27/18639	0.111111111111111	0.676134508651649	0.844102541318094	1
GO:0016229	steroid dehydrogenase activity	4/3063	35/18639	0.114285714285714	0.695452637470267	0.849640642904679	1
GO:0015085	calcium ion transmembrane transporter activity	20/3063	147/18639	0.136054421768707	0.827919806512223	0.851699242324623	1
GO:0042826	histone deacetylase binding	17/3063	127/18639	0.133858267716535	0.814555746643325	0.854091166057481	1
GO:0005245	voltage-gated calcium channel activity	5/3063	43/18639	0.116279069767442	0.707582625333121	0.856969973222864	1
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0000099	sulfur amino acid transmembrane transporter activity	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0004954	prostanoid receptor activity	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0005114	type II transforming growth factor beta receptor binding	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0008046	axon guidance receptor activity	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0008199	ferric iron binding	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0008503	benzodiazepine receptor activity	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0015173	aromatic amino acid transmembrane transporter activity	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0042608	T cell receptor binding	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0043522	leucine zipper domain binding	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0070990	snRNP binding	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/3063	11/18639	0.0909090909090909	0.553200961624076	0.861287844859639	1
GO:0005242	inward rectifier potassium channel activity	3/3063	28/18639	0.107142857142857	0.651986847628376	0.861614343224823	1
GO:0008083	growth factor activity	22/3063	162/18639	0.135802469135802	0.826386621685348	0.86355384062157	1
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	2/3063	20/18639	0.1	0.608521057786484	0.864066389781228	1
GO:0005326	neurotransmitter transmembrane transporter activity	2/3063	20/18639	0.1	0.608521057786484	0.864066389781228	1
GO:0016408	C-acyltransferase activity	2/3063	20/18639	0.1	0.608521057786484	0.864066389781228	1
GO:0140664	ATP-dependent DNA damage sensor activity	2/3063	20/18639	0.1	0.608521057786484	0.864066389781228	1
GO:0004033	aldo-keto reductase (NADPH) activity	4/3063	36/18639	0.111111111111111	0.676134508651649	0.864911812502627	1
GO:0004190	aspartic-type endopeptidase activity	4/3063	36/18639	0.111111111111111	0.676134508651649	0.864911812502627	1
GO:0055106	ubiquitin-protein transferase regulator activity	4/3063	36/18639	0.111111111111111	0.676134508651649	0.864911812502627	1
GO:0042277	peptide binding	35/3063	249/18639	0.140562248995984	0.855350884438833	0.866533434584486	1
GO:0008168	methyltransferase activity	28/3063	204/18639	0.137254901960784	0.835224981275566	0.875372102457784	1
GO:0001664	G protein-coupled receptor binding	42/3063	297/18639	0.141414141414141	0.860534829193007	0.876960973809475	1
GO:0004181	metallocarboxypeptidase activity	3/3063	29/18639	0.103448275862069	0.629504542537742	0.877372453359531	1
GO:0099604	ligand-gated calcium channel activity	3/3063	29/18639	0.103448275862069	0.629504542537742	0.877372453359531	1
GO:0106222	lncRNA binding	3/3063	29/18639	0.103448275862069	0.629504542537742	0.877372453359531	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	17/3063	130/18639	0.130769230769231	0.795758306336171	0.878199539341022	1
GO:0070001	aspartic-type peptidase activity	4/3063	37/18639	0.108108108108108	0.657860603012415	0.878831858256568	1
GO:0005248	voltage-gated sodium channel activity	2/3063	21/18639	0.0952380952380952	0.579543864558556	0.881894090548029	1
GO:0036122	BMP binding	2/3063	21/18639	0.0952380952380952	0.579543864558556	0.881894090548029	1
GO:0070182	DNA polymerase binding	2/3063	21/18639	0.0952380952380952	0.579543864558556	0.881894090548029	1
GO:0051539	4 iron, 4 sulfur cluster binding	5/3063	45/18639	0.111111111111111	0.676134508651649	0.882812387521955	1
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/3063	12/18639	0.0833333333333333	0.507100881488737	0.884096269338645	1
GO:0004126	cytidine deaminase activity	1/3063	12/18639	0.0833333333333333	0.507100881488737	0.884096269338645	1
GO:0008179	adenylate cyclase binding	1/3063	12/18639	0.0833333333333333	0.507100881488737	0.884096269338645	1
GO:0015132	prostaglandin transmembrane transporter activity	1/3063	12/18639	0.0833333333333333	0.507100881488737	0.884096269338645	1
GO:0015166	polyol transmembrane transporter activity	1/3063	12/18639	0.0833333333333333	0.507100881488737	0.884096269338645	1
GO:0016423	tRNA (guanine) methyltransferase activity	1/3063	12/18639	0.0833333333333333	0.507100881488737	0.884096269338645	1
GO:0070008	serine-type exopeptidase activity	1/3063	12/18639	0.0833333333333333	0.507100881488737	0.884096269338645	1
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/3063	12/18639	0.0833333333333333	0.507100881488737	0.884096269338645	1
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/3063	12/18639	0.0833333333333333	0.507100881488737	0.884096269338645	1
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/3063	12/18639	0.0833333333333333	0.507100881488737	0.884096269338645	1
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/3063	12/18639	0.0833333333333333	0.507100881488737	0.884096269338645	1
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/3063	12/18639	0.0833333333333333	0.507100881488737	0.884096269338645	1
GO:0005262	calcium channel activity	17/3063	131/18639	0.129770992366412	0.789683815448109	0.88549860491319	1
GO:0016887	ATP hydrolysis activity	60/3063	417/18639	0.143884892086331	0.875569867318682	0.887574439906411	1
GO:0016829	lyase activity	27/3063	200/18639	0.135	0.821503428011753	0.891318920298742	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/3063	30/18639	0.1	0.608521057786484	0.891514829551634	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	3/3063	30/18639	0.1	0.608521057786484	0.891514829551634	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	5/3063	46/18639	0.108695652173913	0.661435932376613	0.894162332558912	1
GO:0008649	rRNA methyltransferase activity	2/3063	22/18639	0.0909090909090909	0.553200961624076	0.897535556756569	1
GO:0031683	G-protein beta/gamma-subunit complex binding	2/3063	22/18639	0.0909090909090909	0.553200961624076	0.897535556756569	1
GO:0034062	5'-3' RNA polymerase activity	2/3063	22/18639	0.0909090909090909	0.553200961624076	0.897535556756569	1
GO:0097747	RNA polymerase activity	2/3063	22/18639	0.0909090909090909	0.553200961624076	0.897535556756569	1
GO:0005506	iron ion binding	20/3063	154/18639	0.12987012987013	0.790287088034395	0.900699271857293	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/3063	13/18639	0.0769230769230769	0.468093121374218	0.903155330218858	1
GO:0004465	lipoprotein lipase activity	1/3063	13/18639	0.0769230769230769	0.468093121374218	0.903155330218858	1
GO:0004993	G protein-coupled serotonin receptor activity	1/3063	13/18639	0.0769230769230769	0.468093121374218	0.903155330218858	1
GO:0005035	death receptor activity	1/3063	13/18639	0.0769230769230769	0.468093121374218	0.903155330218858	1
GO:0005542	folic acid binding	1/3063	13/18639	0.0769230769230769	0.468093121374218	0.903155330218858	1
GO:0008417	fucosyltransferase activity	1/3063	13/18639	0.0769230769230769	0.468093121374218	0.903155330218858	1
GO:0009982	pseudouridine synthase activity	1/3063	13/18639	0.0769230769230769	0.468093121374218	0.903155330218858	1
GO:0030955	potassium ion binding	1/3063	13/18639	0.0769230769230769	0.468093121374218	0.903155330218858	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/3063	13/18639	0.0769230769230769	0.468093121374218	0.903155330218858	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/3063	13/18639	0.0769230769230769	0.468093121374218	0.903155330218858	1
GO:0061459	L-arginine transmembrane transporter activity	1/3063	13/18639	0.0769230769230769	0.468093121374218	0.903155330218858	1
GO:0071714	icosanoid transmembrane transporter activity	1/3063	13/18639	0.0769230769230769	0.468093121374218	0.903155330218858	1
GO:0071837	HMG box domain binding	1/3063	13/18639	0.0769230769230769	0.468093121374218	0.903155330218858	1
GO:1901338	catecholamine binding	1/3063	13/18639	0.0769230769230769	0.468093121374218	0.903155330218858	1
GO:0005164	tumor necrosis factor receptor binding	3/3063	31/18639	0.0967741935483871	0.588891346244984	0.904175742900649	1
GO:0140359	ABC-type transporter activity	5/3063	47/18639	0.106382978723404	0.64736282743243	0.904548709693753	1
GO:0003887	DNA-directed DNA polymerase activity	2/3063	23/18639	0.0869565217391304	0.52914874590129	0.911227625867702	1
GO:0015144	carbohydrate transmembrane transporter activity	4/3063	40/18639	0.1	0.608521057786484	0.913364569391915	1
GO:0071855	neuropeptide receptor binding	4/3063	40/18639	0.1	0.608521057786484	0.913364569391915	1
GO:0030515	snoRNA binding	3/3063	32/18639	0.09375	0.570488491674829	0.915484205525669	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	3/3063	32/18639	0.09375	0.570488491674829	0.915484205525669	1
GO:0071813	lipoprotein particle binding	3/3063	32/18639	0.09375	0.570488491674829	0.915484205525669	1
GO:0071814	protein-lipid complex binding	3/3063	32/18639	0.09375	0.570488491674829	0.915484205525669	1
GO:0099094	ligand-gated monoatomic cation channel activity	17/3063	136/18639	0.125	0.760651322233105	0.916905877092433	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	15/3063	122/18639	0.122950819672131	0.748181628426005	0.91744361000988	1
GO:0005344	oxygen carrier activity	1/3063	14/18639	0.0714285714285714	0.434657898418917	0.919081198550204	1
GO:0008174	mRNA methyltransferase activity	1/3063	14/18639	0.0714285714285714	0.434657898418917	0.919081198550204	1
GO:0008559	ABC-type xenobiotic transporter activity	1/3063	14/18639	0.0714285714285714	0.434657898418917	0.919081198550204	1
GO:0015386	potassium:proton antiporter activity	1/3063	14/18639	0.0714285714285714	0.434657898418917	0.919081198550204	1
GO:0030983	mismatched DNA binding	1/3063	14/18639	0.0714285714285714	0.434657898418917	0.919081198550204	1
GO:0031404	chloride ion binding	1/3063	14/18639	0.0714285714285714	0.434657898418917	0.919081198550204	1
GO:0043176	amine binding	1/3063	14/18639	0.0714285714285714	0.434657898418917	0.919081198550204	1
GO:1901474	azole transmembrane transporter activity	1/3063	14/18639	0.0714285714285714	0.434657898418917	0.919081198550204	1
GO:1990825	sequence-specific mRNA binding	1/3063	14/18639	0.0714285714285714	0.434657898418917	0.919081198550204	1
GO:0004536	DNA nuclease activity	7/3063	64/18639	0.109375	0.665569906953967	0.919122350345585	1
GO:0015103	inorganic anion transmembrane transporter activity	21/3063	165/18639	0.127272727272727	0.774481346273707	0.922469402941773	1
GO:0016763	pentosyltransferase activity	5/3063	49/18639	0.102040816326531	0.620939854884167	0.922679535351181	1
GO:0042287	MHC protein binding	4/3063	41/18639	0.0975609756097561	0.593679080767301	0.922752560091368	1
GO:0005315	phosphate transmembrane transporter activity	2/3063	24/18639	0.0833333333333333	0.507100881488737	0.923188361270152	1
GO:0015149	hexose transmembrane transporter activity	2/3063	24/18639	0.0833333333333333	0.507100881488737	0.923188361270152	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/3063	24/18639	0.0833333333333333	0.507100881488737	0.923188361270152	1
GO:0048027	mRNA 5'-UTR binding	2/3063	24/18639	0.0833333333333333	0.507100881488737	0.923188361270152	1
GO:0055056	D-glucose transmembrane transporter activity	2/3063	24/18639	0.0833333333333333	0.507100881488737	0.923188361270152	1
GO:0140612	DNA damage sensor activity	2/3063	24/18639	0.0833333333333333	0.507100881488737	0.923188361270152	1
GO:0015294	solute:monoatomic cation symporter activity	14/3063	116/18639	0.120689655172414	0.734421966294032	0.923720861317284	1
GO:0019956	chemokine binding	3/3063	33/18639	0.0909090909090909	0.553200961624076	0.925562859419003	1
GO:0019843	rRNA binding	7/3063	65/18639	0.107692307692308	0.655330369923906	0.926405369466724	1
GO:0008514	organic anion transmembrane transporter activity	36/3063	269/18639	0.133828996282528	0.814377623803473	0.928535318968505	1
GO:0016741	transferase activity, transferring one-carbon groups	28/3063	215/18639	0.130232558139535	0.792492540373095	0.929960607741854	1
GO:0000774	adenyl-nucleotide exchange factor activity	1/3063	15/18639	0.0666666666666667	0.405680705190989	0.932388811373867	1
GO:0004953	icosanoid receptor activity	1/3063	15/18639	0.0666666666666667	0.405680705190989	0.932388811373867	1
GO:0034483	heparan sulfate sulfotransferase activity	1/3063	15/18639	0.0666666666666667	0.405680705190989	0.932388811373867	1
GO:0050780	dopamine receptor binding	1/3063	15/18639	0.0666666666666667	0.405680705190989	0.932388811373867	1
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/3063	15/18639	0.0666666666666667	0.405680705190989	0.932388811373867	1
GO:0140161	monocarboxylate:sodium symporter activity	1/3063	15/18639	0.0666666666666667	0.405680705190989	0.932388811373867	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	16/3063	132/18639	0.121212121212121	0.737601282165435	0.932552518030636	1
GO:0008483	transaminase activity	2/3063	25/18639	0.08	0.486816846229187	0.933616825184931	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/3063	25/18639	0.08	0.486816846229187	0.933616825184931	1
GO:0015020	glucuronosyltransferase activity	3/3063	34/18639	0.0882352941176471	0.536930345105721	0.93452724285246	1
GO:0003684	damaged DNA binding	8/3063	74/18639	0.108108108108108	0.657860603012415	0.935348907919887	1
GO:0015145	monosaccharide transmembrane transporter activity	2/3063	26/18639	0.0769230769230769	0.468093121374218	0.942693433028633	1
GO:0030527	structural constituent of chromatin	11/3063	98/18639	0.112244897959184	0.683033840372584	0.943288098674525	1
GO:0015385	sodium:proton antiporter activity	1/3063	16/18639	0.0625	0.380325661116552	0.943508499451715	1
GO:0015562	efflux transmembrane transporter activity	1/3063	16/18639	0.0625	0.380325661116552	0.943508499451715	1
GO:0016722	oxidoreductase activity, acting on metal ions	1/3063	16/18639	0.0625	0.380325661116552	0.943508499451715	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/3063	16/18639	0.0625	0.380325661116552	0.943508499451715	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	5/3063	52/18639	0.0961538461538462	0.585116401717773	0.944163704043024	1
GO:0005126	cytokine receptor binding	36/3063	275/18639	0.130909090909091	0.79660938473867	0.947363509141177	1
GO:0003697	single-stranded DNA binding	14/3063	121/18639	0.115702479338843	0.704073951157915	0.947421037287308	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	5/3063	53/18639	0.0943396226415094	0.57407646960989	0.950024901646876	1
GO:0005044	scavenger receptor activity	2/3063	27/18639	0.0740740740740741	0.450756339101099	0.950580704365476	1
GO:0008395	steroid hydroxylase activity	2/3063	27/18639	0.0740740740740741	0.450756339101099	0.950580704365476	1
GO:0140104	molecular carrier activity	32/3063	249/18639	0.1285140562249	0.782035094344075	0.951218280927336	1
GO:0004549	tRNA-specific ribonuclease activity	1/3063	17/18639	0.0588235294117647	0.357953563403814	0.952799884630225	1
GO:0017110	nucleoside diphosphate phosphatase activity	1/3063	17/18639	0.0588235294117647	0.357953563403814	0.952799884630225	1
GO:0017069	snRNA binding	5/3063	54/18639	0.0925925925925926	0.563445423876374	0.955321484162141	1
GO:0015079	potassium ion transmembrane transporter activity	19/3063	160/18639	0.11875	0.72261875612145	0.957313866124726	1
GO:0051119	sugar transmembrane transporter activity	2/3063	28/18639	0.0714285714285714	0.434657898418917	0.957424270607065	1
GO:0015293	symporter activity	17/3063	146/18639	0.116438356164384	0.7085519166007	0.958583025832953	1
GO:1901682	sulfur compound transmembrane transporter activity	6/3063	63/18639	0.0952380952380952	0.579543864558556	0.959226827008565	1
GO:0015171	amino acid transmembrane transporter activity	11/3063	102/18639	0.107843137254902	0.656248199573659	0.959579684678507	1
GO:0003746	translation elongation factor activity	1/3063	18/18639	0.0555555555555556	0.338067254325824	0.960563495057549	1
GO:0004970	glutamate-gated receptor activity	1/3063	18/18639	0.0555555555555556	0.338067254325824	0.960563495057549	1
GO:0034185	apolipoprotein binding	1/3063	18/18639	0.0555555555555556	0.338067254325824	0.960563495057549	1
GO:0042887	amide transmembrane transporter activity	3/3063	38/18639	0.0789473684210526	0.480411361410382	0.961286562647812	1
GO:0030170	pyridoxal phosphate binding	5/3063	56/18639	0.0892857142857143	0.543322373023646	0.964406401202981	1
GO:0004896	cytokine receptor activity	10/3063	96/18639	0.104166666666667	0.633876101860921	0.96497261664305	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/3063	19/18639	0.0526315789473684	0.320274240940255	0.96705047291259	1
GO:0022821	solute:potassium antiporter activity	1/3063	19/18639	0.0526315789473684	0.320274240940255	0.96705047291259	1
GO:0031420	alkali metal ion binding	1/3063	19/18639	0.0526315789473684	0.320274240940255	0.96705047291259	1
GO:0099589	serotonin receptor activity	1/3063	19/18639	0.0526315789473684	0.320274240940255	0.96705047291259	1
GO:0015081	sodium ion transmembrane transporter activity	19/3063	164/18639	0.115853658536585	0.70499390841117	0.967868264222809	1
GO:0070279	vitamin B6 binding	5/3063	57/18639	0.087719298245614	0.533790401567091	0.968280385440659	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	65/3063	484/18639	0.134297520661157	0.817228693308294	0.971638860650642	1
GO:0005244	voltage-gated monoatomic ion channel activity	20/3063	173/18639	0.115606936416185	0.703492552354317	0.971657844327229	1
GO:0001614	purinergic nucleotide receptor activity	1/3063	20/18639	0.05	0.304260528893242	0.972470687814241	1
GO:0016502	nucleotide receptor activity	1/3063	20/18639	0.05	0.304260528893242	0.972470687814241	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/3063	20/18639	0.05	0.304260528893242	0.972470687814241	1
GO:0046943	carboxylic acid transmembrane transporter activity	22/3063	188/18639	0.117021276595745	0.712099110175673	0.972697493894273	1
GO:0072349	modified amino acid transmembrane transporter activity	2/3063	31/18639	0.0645161290322581	0.39259423082999	0.972920555878882	1
GO:0044183	protein folding chaperone	7/3063	75/18639	0.0933333333333333	0.567952987267385	0.972985015908092	1
GO:0001530	lipopolysaccharide binding	3/3063	41/18639	0.0731707317073171	0.445259310575476	0.974189432181418	1
GO:0008227	G protein-coupled amine receptor activity	3/3063	41/18639	0.0731707317073171	0.445259310575476	0.974189432181418	1
GO:0140828	metal cation:monoatomic cation antiporter activity	3/3063	41/18639	0.0731707317073171	0.445259310575476	0.974189432181418	1
GO:0005342	organic acid transmembrane transporter activity	22/3063	189/18639	0.116402116402116	0.708331390016013	0.974539798215996	1
GO:0036002	pre-mRNA binding	5/3063	59/18639	0.0847457627118644	0.515695811683461	0.974884361733487	1
GO:0022832	voltage-gated channel activity	20/3063	175/18639	0.114285714285714	0.695452637470267	0.97548112464033	1
GO:0140223	general transcription initiation factor activity	6/3063	68/18639	0.0882352941176471	0.536930345105721	0.976390000825006	1
GO:0015106	bicarbonate transmembrane transporter activity	2/3063	32/18639	0.0625	0.380325661116552	0.976749645902429	1
GO:0031369	translation initiation factor binding	2/3063	32/18639	0.0625	0.380325661116552	0.976749645902429	1
GO:0042910	xenobiotic transmembrane transporter activity	2/3063	32/18639	0.0625	0.380325661116552	0.976749645902429	1
GO:0001846	opsonin binding	1/3063	21/18639	0.0476190476190476	0.289771932279278	0.976999517677552	1
GO:0015174	basic amino acid transmembrane transporter activity	1/3063	21/18639	0.0476190476190476	0.289771932279278	0.976999517677552	1
GO:0061891	calcium ion sensor activity	1/3063	21/18639	0.0476190476190476	0.289771932279278	0.976999517677552	1
GO:0004520	DNA endonuclease activity	3/3063	42/18639	0.0714285714285714	0.434657898418917	0.977495106565492	1
GO:0005267	potassium channel activity	13/3063	124/18639	0.104838709677419	0.637965625098733	0.977557898734857	1
GO:0004386	helicase activity	17/3063	155/18639	0.109677419354839	0.667410192410982	0.979110016670214	1
GO:0001216	DNA-binding transcription activator activity	65/3063	491/18639	0.132382892057026	0.805577775073757	0.979403377682544	1
GO:0140784	metal ion sensor activity	1/3063	22/18639	0.0454545454545455	0.276600480812038	0.980783515816646	1
GO:0015291	secondary active transmembrane transporter activity	35/3063	287/18639	0.121951219512195	0.742098850959127	0.981974861117364	1
GO:0017046	peptide hormone binding	4/3063	53/18639	0.0754716981132075	0.459261175687912	0.982206098975653	1
GO:0015370	solute:sodium symporter activity	7/3063	79/18639	0.0886075949367089	0.539195873988024	0.982381415827384	1
GO:0008175	tRNA methyltransferase activity	2/3063	34/18639	0.0588235294117647	0.357953563403814	0.982897317747158	1
GO:0019825	oxygen binding	2/3063	34/18639	0.0588235294117647	0.357953563403814	0.982897317747158	1
GO:0090482	vitamin transmembrane transporter activity	2/3063	34/18639	0.0588235294117647	0.357953563403814	0.982897317747158	1
GO:0140299	molecular sensor activity	6/3063	71/18639	0.0845070422535211	0.514243147425198	0.98317691223112	1
GO:0015297	antiporter activity	14/3063	135/18639	0.103703703703704	0.631058874741539	0.983204557928502	1
GO:0022834	ligand-gated channel activity	21/3063	188/18639	0.111702127659574	0.679730968804051	0.983871838746382	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/3063	23/18639	0.0434782608695652	0.264574372950645	0.983945147177962	1
GO:0042379	chemokine receptor binding	6/3063	72/18639	0.0833333333333333	0.507100881488737	0.98499982701217	1
GO:0034061	DNA polymerase activity	2/3063	35/18639	0.0571428571428571	0.347726318735134	0.98534652721077	1
GO:0005249	voltage-gated potassium channel activity	9/3063	98/18639	0.0918367346938776	0.558845869395751	0.986534261821641	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	3/3063	46/18639	0.0652173913043478	0.396861559425968	0.987103835493352	1
GO:0001848	complement binding	1/3063	25/18639	0.04	0.243408423114594	0.988793826622771	1
GO:0005251	delayed rectifier potassium channel activity	1/3063	25/18639	0.04	0.243408423114594	0.988793826622771	1
GO:0017056	structural constituent of nuclear pore	1/3063	25/18639	0.04	0.243408423114594	0.988793826622771	1
GO:0015276	ligand-gated monoatomic ion channel activity	20/3063	186/18639	0.10752688172043	0.654323718049983	0.989382911879697	1
GO:0046873	metal ion transmembrane transporter activity	57/3063	450/18639	0.126666666666667	0.77079333986288	0.989562473052372	1
GO:0008188	neuropeptide receptor activity	3/3063	48/18639	0.0625	0.380325661116552	0.990283590332004	1
GO:0008173	RNA methyltransferase activity	5/3063	67/18639	0.0746268656716418	0.454120192377973	0.990476068149762	1
GO:0008094	ATP-dependent activity, acting on DNA	23/3063	210/18639	0.10952380952381	0.666475444242339	0.990626382134607	1
GO:0008066	glutamate receptor activity	1/3063	26/18639	0.0384615384615385	0.234046560687109	0.990637842366537	1
GO:0019865	immunoglobulin binding	1/3063	26/18639	0.0384615384615385	0.234046560687109	0.990637842366537	1
GO:0140597	protein carrier chaperone	20/3063	188/18639	0.106382978723404	0.64736282743243	0.990944853855902	1
GO:0022843	voltage-gated monoatomic cation channel activity	14/3063	143/18639	0.0979020979020979	0.595754881749005	0.99175036889513	1
GO:0048020	CCR chemokine receptor binding	3/3063	50/18639	0.06	0.36511263467189	0.992700105059807	1
GO:0008527	taste receptor activity	1/3063	28/18639	0.0357142857142857	0.217328949209459	0.993465695257956	1
GO:0050698	proteoglycan sulfotransferase activity	1/3063	28/18639	0.0357142857142857	0.217328949209459	0.993465695257956	1
GO:0016782	transferase activity, transferring sulphur-containing groups	5/3063	70/18639	0.0714285714285714	0.434657898418917	0.993466064623824	1
GO:0004497	monooxygenase activity	9/3063	106/18639	0.0849056603773585	0.516668822648901	0.994182301238396	1
GO:0005261	monoatomic cation channel activity	40/3063	341/18639	0.117302052785924	0.713807692418163	0.99432363394995	1
GO:0005216	monoatomic ion channel activity	55/3063	448/18639	0.122767857142857	0.747068262907514	0.994585554770117	1
GO:0022824	transmitter-gated monoatomic ion channel activity	4/3063	63/18639	0.0634920634920635	0.386362576372371	0.99526299042103	1
GO:0022835	transmitter-gated channel activity	4/3063	63/18639	0.0634920634920635	0.386362576372371	0.99526299042103	1
GO:0005452	solute:inorganic anion antiporter activity	1/3063	31/18639	0.032258064516129	0.196297115414995	0.996190218569336	1
GO:0061775	cohesin loader activity	14/3063	153/18639	0.0915032679738562	0.556816654183711	0.99678236431342	1
GO:0008009	chemokine activity	2/3063	45/18639	0.0444444444444444	0.27045380346066	0.996969876724521	1
GO:0140097	catalytic activity, acting on DNA	38/3063	336/18639	0.113095238095238	0.688208339163285	0.99697603542462	1
GO:0042923	neuropeptide binding	1/3063	33/18639	0.0303030303030303	0.184400320541359	0.997341249897678	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/3063	34/18639	0.0294117647058824	0.178976781701907	0.99777894481133	1
GO:0140658	ATP-dependent chromatin remodeler activity	14/3063	158/18639	0.0886075949367089	0.539195873988024	0.998030543447247	1
GO:0038187	pattern recognition receptor activity	2/3063	48/18639	0.0416666666666667	0.253550440744368	0.998128140643244	1
GO:0000510	H3-H4 histone complex chaperone activity	13/3063	151/18639	0.0860927152317881	0.523892301405582	0.998265228165256	1
GO:0140584	chromatin extrusion motor activity	13/3063	151/18639	0.0860927152317881	0.523892301405582	0.998265228165256	1
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	13/3063	151/18639	0.0860927152317881	0.523892301405582	0.998265228165256	1
GO:0140849	ATP-dependent H2AZ histone chaperone activity	13/3063	151/18639	0.0860927152317881	0.523892301405582	0.998265228165256	1
GO:0003689	DNA clamp loader activity	14/3063	160/18639	0.0875	0.532455925563173	0.99838734645716	1
GO:0015616	DNA translocase activity	13/3063	152/18639	0.0855263157894737	0.520445641527914	0.998434441088131	1
GO:0140674	ATP-dependent histone chaperone activity	13/3063	152/18639	0.0855263157894737	0.520445641527914	0.998434441088131	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/3063	36/18639	0.0277777777777778	0.169033627162912	0.998450080258781	1
GO:0022836	gated channel activity	34/3063	318/18639	0.106918238993711	0.650619998891209	0.998684411415076	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	4/3063	73/18639	0.0547945205479452	0.333436196047388	0.998818808339897	1
GO:0051082	unfolded protein binding	9/3063	121/18639	0.0743801652892562	0.452618968601517	0.998917152568221	1
GO:0005179	hormone activity	10/3063	132/18639	0.0757575757575758	0.461000801353397	0.999153829965843	1
GO:0008146	sulfotransferase activity	2/3063	53/18639	0.0377358490566038	0.229630587843956	0.999167236917484	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/3063	53/18639	0.0377358490566038	0.229630587843956	0.999167236917484	1
GO:0030594	neurotransmitter receptor activity	6/3063	97/18639	0.0618556701030928	0.376404778012258	0.99931975396562	1
GO:0003724	RNA helicase activity	4/3063	77/18639	0.051948051948052	0.316114835213758	0.999332200583468	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	2/3063	56/18639	0.0357142857142857	0.217328949209459	0.99948969418504	1
GO:0008186	ATP-dependent activity, acting on RNA	4/3063	79/18639	0.0506329113924051	0.308111927993156	0.999499264545591	1
GO:0140713	histone chaperone activity	13/3063	164/18639	0.0792682926829268	0.482364253123432	0.999559749005964	1
GO:0005125	cytokine activity	21/3063	234/18639	0.0897435897435897	0.546108641603255	0.999685926511892	1
GO:0140375	immune receptor activity	11/3063	156/18639	0.0705128205128205	0.4290853612597	0.999852151423367	1
GO:0098960	postsynaptic neurotransmitter receptor activity	2/3063	69/18639	0.0289855072463768	0.17638291530043	0.999940472997064	1
GO:0008528	G protein-coupled peptide receptor activity	6/3063	122/18639	0.0491803278688525	0.299272651370402	0.999977449254949	1
GO:0001653	peptide receptor activity	6/3063	128/18639	0.046875	0.285244245837414	0.999990369719479	1
GO:0003730	mRNA 3'-UTR binding	16/3063	262/18639	0.0610687022900763	0.371615913152051	0.999999889146799	1
GO:0003735	structural constituent of ribosome	7/3063	175/18639	0.04	0.243408423114594	0.999999947571397	1
GO:0003823	antigen binding	5/3063	174/18639	0.028735632183908	0.174862372927151	0.999999998496837	1
GO:0045182	translation regulator activity	13/3063	356/18639	0.0365168539325843	0.222212745820907	0.999999999999997	1
GO:0004984	olfactory receptor activity	4/3063	419/18639	0.00954653937947494	0.0580927024139841	1	1
GO:0030371	translation repressor activity	6/3063	329/18639	0.0182370820668693	0.110976484702702	1	1