ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 92/2936 175/18639 0.525714285714286 3.3374620474893 1.11870489034359e-29 1.46214729167908e-26 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 34/2936 68/18639 0.5 3.17421662125341 4.69696923598905e-11 3.06946939571884e-08 GO:0009055 electron transfer activity 42/2936 116/18639 0.362068965517241 2.29857065676971 5.74340018717581e-08 2.5022080148796e-05 GO:0003954 NADH dehydrogenase activity 22/2936 44/18639 0.5 3.17421662125341 1.23449308846815e-07 3.66456082390416e-05 GO:0008137 NADH dehydrogenase (ubiquinone) activity 21/2936 41/18639 0.51219512195122 3.25163653884495 1.40189779032294e-07 3.66456082390416e-05 GO:0015078 proton transmembrane transporter activity 57/2936 185/18639 0.308108108108108 1.9560037557994 1.98912631894802e-07 4.33298016477511e-05 GO:0022853 active monoatomic ion transmembrane transporter activity 41/2936 118/18639 0.347457627118644 2.20581155036254 3.00422142025771e-07 5.60931056610976e-05 GO:0016651 oxidoreductase activity, acting on NAD(P)H 33/2936 88/18639 0.375 2.38066246594005 5.8219966403051e-07 9.13733269847594e-05 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 25/2936 58/18639 0.431034482758621 2.73639363901156 6.49097772734905e-07 9.13733269847594e-05 GO:0004812 aminoacyl-tRNA ligase activity 20/2936 41/18639 0.48780487804878 3.09679670366186 7.69018054194608e-07 9.13733269847594e-05 GO:0016875 ligase activity, forming carbon-oxygen bonds 20/2936 41/18639 0.48780487804878 3.09679670366186 7.69018054194608e-07 9.13733269847594e-05 GO:0045296 cadherin binding 86/2936 334/18639 0.25748502994012 1.63462652351972 1.47948694637135e-06 0.000161140786575613 GO:0004857 enzyme inhibitor activity 100/2936 416/18639 0.240384615384615 1.52606568329491 5.96825871038343e-06 0.000600039548805473 GO:0016874 ligase activity 49/2936 167/18639 0.293413173652695 1.86271394540619 6.43144872150852e-06 0.00060042167707226 GO:0004129 cytochrome-c oxidase activity 10/2936 15/18639 0.666666666666667 4.23228882833787 1.29332555001909e-05 0.00105648530867184 GO:0055105 ubiquitin-protein transferase inhibitor activity 10/2936 15/18639 0.666666666666667 4.23228882833787 1.29332555001909e-05 0.00105648530867184 GO:0016675 oxidoreductase activity, acting on a heme group of donors 10/2936 16/18639 0.625 3.96777077656676 2.95987016870551e-05 0.00227561782970476 GO:0043021 ribonucleoprotein complex binding 49/2936 177/18639 0.27683615819209 1.75747586939454 3.54544536355208e-05 0.00257438727231254 GO:0015399 primary active transmembrane transporter activity 46/2936 166/18639 0.27710843373494 1.75920439250189 5.89744846939006e-05 0.00397947940687724 GO:0030742 GTP-dependent protein binding 11/2936 20/18639 0.55 3.49163828337875 6.09098529100563e-05 0.00397947940687724 GO:0023023 MHC protein complex binding 16/2936 37/18639 0.432432432432432 2.74526842919213 6.39396079146305e-05 0.00397947940687724 GO:0023026 MHC class II protein complex binding 13/2936 27/18639 0.481481481481481 3.05665304268846 8.06008379440499e-05 0.00459636694054745 GO:0005201 extracellular matrix structural constituent 46/2936 168/18639 0.273809523809524 1.73826148306734 8.08848046156017e-05 0.00459636694054745 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 11/2936 21/18639 0.523809523809524 3.32536979369404 0.000109704407617959 0.00597431919819466 GO:0098641 cadherin binding involved in cell-cell adhesion 10/2936 18/18639 0.555555555555556 3.52690735694823 0.000119214057750295 0.0062325109391854 GO:0004860 protein kinase inhibitor activity 27/2936 84/18639 0.321428571428571 2.04056782794862 0.000139588976173227 0.00701703045609259 GO:0005518 collagen binding 24/2936 72/18639 0.333333333333333 2.11614441416894 0.000172050898259607 0.0083285379268632 GO:0019210 kinase inhibitor activity 28/2936 90/18639 0.311111111111111 1.97506811989101 0.000198078369705216 0.0092160162942718 GO:0001046 core promoter sequence-specific DNA binding 17/2936 44/18639 0.386363636363636 2.45280375278672 0.000204486972099374 0.0092160162942718 GO:0005178 integrin binding 43/2936 161/18639 0.267080745341615 1.6955442821602 0.000247168832446935 0.0107683221336048 GO:0042171 lysophosphatidic acid acyltransferase activity 11/2936 23/18639 0.478260869565217 3.03620720293804 0.000309556276442433 0.0126434391659456 GO:0071617 lysophospholipid acyltransferase activity 11/2936 23/18639 0.478260869565217 3.03620720293804 0.000309556276442433 0.0126434391659456 GO:0051087 protein-folding chaperone binding 37/2936 134/18639 0.276119402985075 1.75292559681158 0.000321085960097902 0.0127169499953927 GO:0140101 catalytic activity, acting on a tRNA 38/2936 139/18639 0.273381294964029 1.7355429008292 0.000333889139892764 0.0128350913482307 GO:0051082 unfolded protein binding 34/2936 121/18639 0.28099173553719 1.78385727475398 0.00038739445842679 0.0144664159189661 GO:0050840 extracellular matrix binding 22/2936 67/18639 0.328358208955224 2.08456016918134 0.00040141706539477 0.0144996806831364 GO:0043022 ribosome binding 32/2936 112/18639 0.285714285714286 1.81383806928766 0.00041073601816067 0.0144996806831364 GO:0050786 RAGE receptor binding 7/2936 11/18639 0.636363636363636 4.03991206341343 0.00043773468880169 0.0144996806831364 GO:1990948 ubiquitin ligase inhibitor activity 7/2936 11/18639 0.636363636363636 4.03991206341343 0.00043773468880169 0.0144996806831364 GO:0016411 acylglycerol O-acyltransferase activity 13/2936 31/18639 0.419354838709677 2.6622461984706 0.000445937520476992 0.0144996806831364 GO:0001786 phosphatidylserine binding 20/2936 59/18639 0.338983050847458 2.15201126864638 0.000454848437650032 0.0144996806831364 GO:0048027 mRNA 5'-UTR binding 11/2936 24/18639 0.458333333333333 2.90969856948229 0.000490494236109515 0.0152637134903604 GO:0044389 ubiquitin-like protein ligase binding 73/2936 322/18639 0.226708074534162 1.43924107671738 0.000652915006634828 0.0198455793877144 GO:0019843 rRNA binding 21/2936 65/18639 0.323076923076923 2.05103227834835 0.000686827113651371 0.0204018872168714 GO:0031625 ubiquitin protein ligase binding 69/2936 302/18639 0.228476821192053 1.45046984679791 0.000722988603992959 0.0209988023426399 GO:0140296 general transcription initiation factor binding 18/2936 53/18639 0.339622641509434 2.15607166726646 0.000840445276124681 0.0231412906648615 GO:0031386 protein tag activity 8/2936 15/18639 0.533333333333333 3.3858310626703 0.000849871424570277 0.0231412906648615 GO:0141047 molecular tag activity 8/2936 15/18639 0.533333333333333 3.3858310626703 0.000849871424570277 0.0231412906648615 GO:0019838 growth factor binding 36/2936 136/18639 0.264705882352941 1.68046762301651 0.000903597201185526 0.023723411842634 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 7/2936 12/18639 0.583333333333333 3.70325272479564 0.000907552098034965 0.023723411842634 GO:0005520 insulin-like growth factor binding 9/2936 19/18639 0.473684210526316 3.00715258855586 0.00120375524810235 0.0307976695906107 GO:0019887 protein kinase regulator activity 59/2936 255/18639 0.231372549019608 1.46885318159962 0.00122530896611458 0.0307976695906107 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 7/2936 13/18639 0.538461538461538 3.41838713058059 0.00169943417138483 0.0411326011481476 GO:0031994 insulin-like growth factor I binding 7/2936 13/18639 0.538461538461538 3.41838713058059 0.00169943417138483 0.0411326011481476 GO:0005528 FK506 binding 6/2936 10/18639 0.6 3.80905994550409 0.00179543848948389 0.0426661473773716 GO:0019207 kinase regulator activity 64/2936 287/18639 0.222996515679443 1.41567849310256 0.00207361868408851 0.048396778930423 GO:0048306 calcium-dependent protein binding 23/2936 80/18639 0.2875 1.82517455722071 0.00230492523879719 0.0521192021734766 GO:0055106 ubiquitin-protein transferase regulator activity 13/2936 36/18639 0.361111111111111 2.29248978201635 0.00231286436577019 0.0521192021734766 GO:0032977 membrane insertase activity 8/2936 17/18639 0.470588235294118 2.98749799647379 0.00238877738378893 0.0529174922137648 GO:0033218 amide binding 56/2936 247/18639 0.226720647773279 1.43932089708656 0.00259276434186484 0.0564790499136224 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 9/2936 21/18639 0.428571428571429 2.72075710393149 0.00284136285360462 0.0608796926173972 GO:0072341 modified amino acid binding 25/2936 91/18639 0.274725274725275 1.74407506662275 0.00301577917282829 0.0635745706272027 GO:0140311 protein sequestering activity 12/2936 33/18639 0.363636363636364 2.30852117909339 0.00315650871246281 0.0649085973126252 GO:0043236 laminin binding 11/2936 29/18639 0.379310344827586 2.40802640233017 0.00317838579036573 0.0649085973126252 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 6/2936 11/18639 0.545454545454545 3.46278176864008 0.00342468305030252 0.0688624730268522 GO:0043178 alcohol binding 25/2936 92/18639 0.271739130434783 1.72511772894207 0.00353355222071832 0.0699750417042249 GO:0035615 clathrin adaptor activity 8/2936 18/18639 0.444444444444444 2.82152588555858 0.00371104288128686 0.070294681823796 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 8/2936 18/18639 0.444444444444444 2.82152588555858 0.00371104288128686 0.070294681823796 GO:0070064 proline-rich region binding 8/2936 18/18639 0.444444444444444 2.82152588555858 0.00371104288128686 0.070294681823796 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 15/2936 48/18639 0.3125 1.98388538828338 0.00545671038176706 0.101884578128136 GO:0005527 macrolide binding 6/2936 12/18639 0.5 3.17421662125341 0.00594181400257009 0.107860429185543 GO:0097371 MDM2/MDM4 family protein binding 6/2936 12/18639 0.5 3.17421662125341 0.00594181400257009 0.107860429185543 GO:0004540 RNA nuclease activity 30/2936 121/18639 0.247933884297521 1.57399171301822 0.00650685366713146 0.116499421136176 GO:0015485 cholesterol binding 16/2936 54/18639 0.296296296296296 1.88101725703906 0.00738974312117877 0.129379471496308 GO:0032934 sterol binding 19/2936 68/18639 0.279411764705882 1.77382693540632 0.00742422368953567 0.129379471496308 GO:0043024 ribosomal small subunit binding 8/2936 20/18639 0.4 2.53937329700272 0.00796769471221948 0.135830129074086 GO:0003779 actin binding 89/2936 443/18639 0.200902934537246 1.27541886813342 0.00806151783509758 0.135830129074086 GO:0140098 catalytic activity, acting on RNA 79/2936 387/18639 0.204134366925065 1.29593340092516 0.00810615919493397 0.135830129074086 GO:0008374 O-acyltransferase activity 16/2936 55/18639 0.290909090909091 1.84681694327471 0.00893056276010656 0.145903069093241 GO:0140313 molecular sequestering activity 16/2936 55/18639 0.290909090909091 1.84681694327471 0.00893056276010656 0.145903069093241 GO:0030291 protein serine/threonine kinase inhibitor activity 14/2936 46/18639 0.304347826086957 1.93213185641512 0.00919957394360923 0.1468536611802 GO:0046332 SMAD binding 21/2936 79/18639 0.265822784810127 1.68755820370434 0.00928813799156033 0.1468536611802 GO:0005525 GTP binding 77/2936 378/18639 0.203703703703704 1.29319936421435 0.0093258254613287 0.1468536611802 GO:0019855 calcium channel inhibitor activity 6/2936 13/18639 0.461538461538462 2.93004611192622 0.00957813957215744 0.147277981421291 GO:0039706 co-receptor binding 6/2936 13/18639 0.461538461538462 2.93004611192622 0.00957813957215744 0.147277981421291 GO:0051879 Hsp90 protein binding 13/2936 42/18639 0.30952380952381 1.9649912417283 0.0102118589600837 0.151762239659979 GO:0019003 GDP binding 20/2936 75/18639 0.266666666666667 1.69291553133515 0.0105705227308518 0.151762239659979 GO:0001221 transcription coregulator binding 28/2936 115/18639 0.243478260869565 1.54570548513209 0.0107610377516631 0.151762239659979 GO:0004549 tRNA-specific ribonuclease activity 7/2936 17/18639 0.411764705882353 2.61406074691457 0.0107954786792503 0.151762239659979 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 7/2936 17/18639 0.411764705882353 2.61406074691457 0.0107954786792503 0.151762239659979 GO:0051787 misfolded protein binding 7/2936 17/18639 0.411764705882353 2.61406074691457 0.0107954786792503 0.151762239659979 GO:0070402 NADPH binding 7/2936 17/18639 0.411764705882353 2.61406074691457 0.0107954786792503 0.151762239659979 GO:0017025 TBP-class protein binding 9/2936 25/18639 0.36 2.28543596730245 0.0109148053007177 0.151762239659979 GO:0019211 phosphatase activator activity 9/2936 25/18639 0.36 2.28543596730245 0.0109148053007177 0.151762239659979 GO:0140312 cargo adaptor activity 8/2936 21/18639 0.380952380952381 2.41845075905021 0.0111223604713671 0.153020264590282 GO:0002020 protease binding 32/2936 136/18639 0.235294117647059 1.4937489982369 0.0113067387815801 0.153936537370054 GO:0016829 lyase activity 44/2936 200/18639 0.22 1.3966553133515 0.0119467038890636 0.160972597762949 GO:0003680 minor groove of adenine-thymine-rich DNA binding 5/2936 10/18639 0.5 3.17421662125341 0.0121506745602756 0.161726115122056 GO:0098631 cell adhesion mediator activity 20/2936 76/18639 0.263157894736842 1.67064032697548 0.0122741130842104 0.161726115122056 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 11/2936 34/18639 0.323529411764706 2.05390487257573 0.0123738420139293 0.161726115122056 GO:0001968 fibronectin binding 10/2936 30/18639 0.333333333333333 2.11614441416894 0.0134452574174851 0.172283837692676 GO:0035925 mRNA 3'-UTR AU-rich region binding 10/2936 30/18639 0.333333333333333 2.11614441416894 0.0134452574174851 0.172283837692676 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 12/2936 39/18639 0.307692307692308 1.95336407461748 0.0140101110560344 0.176069376444586 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 12/2936 39/18639 0.307692307692308 1.95336407461748 0.0140101110560344 0.176069376444586 GO:0034236 protein kinase A catalytic subunit binding 6/2936 14/18639 0.428571428571429 2.72075710393149 0.0145576370476163 0.177820856273219 GO:0042043 neurexin family protein binding 6/2936 14/18639 0.428571428571429 2.72075710393149 0.0145576370476163 0.177820856273219 GO:0044548 S100 protein binding 6/2936 14/18639 0.428571428571429 2.72075710393149 0.0145576370476163 0.177820856273219 GO:0000900 mRNA regulatory element binding translation repressor activity 7/2936 18/18639 0.388888888888889 2.46883514986376 0.015303756005227 0.185203787952145 GO:0051015 actin filament binding 45/2936 209/18639 0.215311004784689 1.36688754025266 0.0161574240787548 0.192482586003843 GO:0004521 RNA endonuclease activity 19/2936 73/18639 0.26027397260274 1.65233193983054 0.0161997585772171 0.192482586003843 GO:0001222 transcription corepressor binding 14/2936 49/18639 0.285714285714286 1.81383806928766 0.0163840859821037 0.192918922329815 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 15/2936 54/18639 0.277777777777778 1.76345367847411 0.0171932806047368 0.197119453950798 GO:0050661 NADP binding 15/2936 54/18639 0.277777777777778 1.76345367847411 0.0171932806047368 0.197119453950798 GO:0051287 NAD binding 15/2936 54/18639 0.277777777777778 1.76345367847411 0.0171932806047368 0.197119453950798 GO:0016835 carbon-oxygen lyase activity 20/2936 79/18639 0.253164556962025 1.60719828924223 0.0187187960723995 0.20807369456196 GO:0004869 cysteine-type endopeptidase inhibitor activity 11/2936 36/18639 0.305555555555556 1.93979904632153 0.0192655667468726 0.20807369456196 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 11/2936 36/18639 0.305555555555556 1.93979904632153 0.0192655667468726 0.20807369456196 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 11/2936 36/18639 0.305555555555556 1.93979904632153 0.0192655667468726 0.20807369456196 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 11/2936 36/18639 0.305555555555556 1.93979904632153 0.0192655667468726 0.20807369456196 GO:0017124 SH3 domain binding 27/2936 115/18639 0.234782608695652 1.49050171780595 0.0193322357444375 0.20807369456196 GO:0003953 NAD+ nucleosidase activity 5/2936 11/18639 0.454545454545455 2.88565147386673 0.0194223341519197 0.20807369456196 GO:0042608 T cell receptor binding 5/2936 11/18639 0.454545454545455 2.88565147386673 0.0194223341519197 0.20807369456196 GO:0016918 retinal binding 7/2936 19/18639 0.368421052631579 2.33889645776567 0.0210024742104169 0.223172632463535 GO:0051019 mitogen-activated protein kinase binding 9/2936 28/18639 0.321428571428571 2.04056782794862 0.0237478626349367 0.248324800422233 GO:0016209 antioxidant activity 21/2936 86/18639 0.244186046511628 1.55019881503073 0.0240512259882194 0.248324800422233 GO:0001618 virus receptor activity 20/2936 81/18639 0.246913580246914 1.56751438086588 0.0242974373448985 0.248324800422233 GO:0019001 guanyl nucleotide binding 78/2936 400/18639 0.195 1.23794448228883 0.0244425125489849 0.248324800422233 GO:0032561 guanyl ribonucleotide binding 78/2936 400/18639 0.195 1.23794448228883 0.0244425125489849 0.248324800422233 GO:0005200 structural constituent of cytoskeleton 26/2936 112/18639 0.232142857142857 1.47374343129622 0.0245094868052548 0.248324800422233 GO:0016859 cis-trans isomerase activity 12/2936 42/18639 0.285714285714286 1.81383806928766 0.0252344854906237 0.253703634894194 GO:0061134 peptidase regulator activity 47/2936 226/18639 0.207964601769911 1.3202493911408 0.0256199977935385 0.255602019879824 GO:0030295 protein kinase activator activity 31/2936 139/18639 0.223021582733813 1.41583762962382 0.0259166112010263 0.255602019879824 GO:0001091 RNA polymerase II general transcription initiation factor binding 8/2936 24/18639 0.333333333333333 2.11614441416894 0.0260099989625222 0.255602019879824 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 10/2936 33/18639 0.303030303030303 1.92376764924449 0.0265638228373188 0.258457578997793 GO:0052689 carboxylic ester hydrolase activity 22/2936 92/18639 0.239130434782609 1.51810360146902 0.0266960774022204 0.258457578997793 GO:0004866 endopeptidase inhibitor activity 35/2936 161/18639 0.217391304347826 1.38009418315365 0.0270893716110301 0.258792970136884 GO:0005080 protein kinase C binding 14/2936 52/18639 0.269230769230769 1.7091935652903 0.0272161009124334 0.258792970136884 GO:0015631 tubulin binding 75/2936 385/18639 0.194805194805195 1.23670777451431 0.0274609720054454 0.258792970136884 GO:0140272 exogenous protein binding 20/2936 82/18639 0.24390243902439 1.54839835183093 0.0275227412769907 0.258792970136884 GO:0005501 retinoid binding 11/2936 38/18639 0.289473684210526 1.83770435967302 0.0286454294430022 0.26261409651012 GO:0019840 isoprenoid binding 11/2936 38/18639 0.289473684210526 1.83770435967302 0.0286454294430022 0.26261409651012 GO:0004300 enoyl-CoA hydratase activity 5/2936 12/18639 0.416666666666667 2.64518051771117 0.0290512771157409 0.26261409651012 GO:0004526 ribonuclease P activity 5/2936 12/18639 0.416666666666667 2.64518051771117 0.0290512771157409 0.26261409651012 GO:0008142 oxysterol binding 6/2936 16/18639 0.375 2.38066246594005 0.0293356221044204 0.26261409651012 GO:0019841 retinol binding 6/2936 16/18639 0.375 2.38066246594005 0.0293356221044204 0.26261409651012 GO:0043023 ribosomal large subunit binding 6/2936 16/18639 0.375 2.38066246594005 0.0293356221044204 0.26261409651012 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 12/2936 43/18639 0.27906976744186 1.77165578860655 0.0301353722228886 0.267938309491942 GO:0001540 amyloid-beta binding 20/2936 83/18639 0.240963855421687 1.52974295000164 0.031061090525896 0.272462049109705 GO:0030165 PDZ domain binding 20/2936 83/18639 0.240963855421687 1.52974295000164 0.031061090525896 0.272462049109705 GO:0004864 protein phosphatase inhibitor activity 14/2936 53/18639 0.264150943396226 1.67694463009614 0.0317915971252377 0.277010782951238 GO:0031072 heat shock protein binding 29/2936 131/18639 0.221374045801527 1.40537835139464 0.0332679161307409 0.284066366133716 GO:0035401 histone H3Y41 kinase activity 26/2936 115/18639 0.226086956521739 1.4352979504798 0.0332851294072957 0.284066366133716 GO:0140801 histone H2AXY142 kinase activity 26/2936 115/18639 0.226086956521739 1.4352979504798 0.0332851294072957 0.284066366133716 GO:0030414 peptidase inhibitor activity 36/2936 169/18639 0.21301775147929 1.35232897473518 0.033470711847431 0.284066366133716 GO:0043014 alpha-tubulin binding 12/2936 44/18639 0.272727272727273 1.73139088432004 0.0356854366946271 0.29937327710819 GO:0019209 kinase activator activity 32/2936 148/18639 0.216216216216216 1.37263421459607 0.0357323880863639 0.29937327710819 GO:0072542 protein phosphatase activator activity 7/2936 21/18639 0.333333333333333 2.11614441416894 0.0364706222131011 0.301810609759687 GO:0060590 ATPase regulator activity 13/2936 49/18639 0.26530612244898 1.68427820719568 0.0364851387467716 0.301810609759687 GO:0070566 adenylyltransferase activity 9/2936 30/18639 0.3 1.90452997275204 0.0367430532872214 0.302032519788669 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 15/2936 59/18639 0.254237288135593 1.61400845148478 0.0370161535233531 0.302375704093891 GO:0031406 carboxylic acid binding 39/2936 187/18639 0.20855614973262 1.3240047938918 0.0375729360119526 0.305017561289578 GO:0000049 tRNA binding 19/2936 80/18639 0.2375 1.50775289509537 0.040003671142727 0.318506719909821 GO:0019208 phosphatase regulator activity 26/2936 117/18639 0.222222222222222 1.41076294277929 0.040333363248411 0.318506719909821 GO:0015036 disulfide oxidoreductase activity 11/2936 40/18639 0.275 1.74581914168937 0.040911273387284 0.318506719909821 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 5/2936 13/18639 0.384615384615385 2.44170509327185 0.0412219880804806 0.318506719909821 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 5/2936 13/18639 0.384615384615385 2.44170509327185 0.0412219880804806 0.318506719909821 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 28/2936 128/18639 0.21875 1.38871977179837 0.0412462169926891 0.318506719909821 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 8/2936 26/18639 0.307692307692308 1.95336407461748 0.0414278059561359 0.318506719909821 GO:0030247 polysaccharide binding 8/2936 26/18639 0.307692307692308 1.95336407461748 0.0414278059561359 0.318506719909821 GO:0043548 phosphatidylinositol 3-kinase binding 8/2936 26/18639 0.307692307692308 1.95336407461748 0.0414278059561359 0.318506719909821 GO:0042605 peptide antigen binding 12/2936 45/18639 0.266666666666667 1.69291553133515 0.0419218845093884 0.320420485694565 GO:0098632 cell-cell adhesion mediator activity 14/2936 55/18639 0.254545454545455 1.61596482536537 0.0425724448233437 0.323501077814595 GO:0043177 organic acid binding 39/2936 189/18639 0.206349206349206 1.3099941611522 0.0434577465346645 0.328319507056685 GO:0016878 acid-thiol ligase activity 9/2936 31/18639 0.290322580645161 1.84309352201811 0.044774856846259 0.336326079873911 GO:0004713 protein tyrosine kinase activity 30/2936 140/18639 0.214285714285714 1.36037855196575 0.0455055381135364 0.339861361796526 GO:0019902 phosphatase binding 39/2936 190/18639 0.205263157894737 1.30309945504087 0.046647707013136 0.346412233330504 GO:0005516 calmodulin binding 42/2936 207/18639 0.202898550724638 1.28808790427674 0.0473737165444764 0.349816087704128 GO:0016836 hydro-lyase activity 15/2936 61/18639 0.245901639344262 1.56109014160004 0.0483505398207113 0.355023345762189 GO:0019212 phosphatase inhibitor activity 14/2936 56/18639 0.25 1.5871083106267 0.0488315828347308 0.356552395335157 GO:0015252 proton channel activity 8/2936 27/18639 0.296296296296296 1.88101725703906 0.0510153561825001 0.369987020759031 GO:0017128 phospholipid scramblase activity 6/2936 18/18639 0.333333333333333 2.11614441416894 0.0515207634109745 0.369987020759031 GO:1990381 ubiquitin-specific protease binding 6/2936 18/18639 0.333333333333333 2.11614441416894 0.0515207634109745 0.369987020759031 GO:0030515 snoRNA binding 9/2936 32/18639 0.28125 1.78549684945504 0.0538975064310268 0.370226771740209 GO:0031369 translation initiation factor binding 9/2936 32/18639 0.28125 1.78549684945504 0.0538975064310268 0.370226771740209 GO:0051059 NF-kappaB binding 9/2936 32/18639 0.28125 1.78549684945504 0.0538975064310268 0.370226771740209 GO:0141108 transporter regulator activity 35/2936 170/18639 0.205882352941176 1.30703037345728 0.0548710392350584 0.370226771740209 GO:0043394 proteoglycan binding 10/2936 37/18639 0.27027027027027 1.71579276824508 0.055577716474659 0.370226771740209 GO:0008135 translation factor activity, RNA binding 19/2936 83/18639 0.228915662650602 1.45325580250156 0.0556647175773884 0.370226771740209 GO:0004601 peroxidase activity 14/2936 57/18639 0.245614035087719 1.55926430517711 0.0557012826756637 0.370226771740209 GO:0005161 platelet-derived growth factor receptor binding 5/2936 14/18639 0.357142857142857 2.26729758660958 0.0560355164320719 0.370226771740209 GO:0008191 metalloendopeptidase inhibitor activity 5/2936 14/18639 0.357142857142857 2.26729758660958 0.0560355164320719 0.370226771740209 GO:0016530 metallochaperone activity 5/2936 14/18639 0.357142857142857 2.26729758660958 0.0560355164320719 0.370226771740209 GO:0031404 chloride ion binding 5/2936 14/18639 0.357142857142857 2.26729758660958 0.0560355164320719 0.370226771740209 GO:0032036 myosin heavy chain binding 5/2936 14/18639 0.357142857142857 2.26729758660958 0.0560355164320719 0.370226771740209 GO:1990825 sequence-specific mRNA binding 5/2936 14/18639 0.357142857142857 2.26729758660958 0.0560355164320719 0.370226771740209 GO:0031492 nucleosomal DNA binding 11/2936 42/18639 0.261904761904762 1.66268489684702 0.0563940720068392 0.370226771740209 GO:0043274 phospholipase binding 7/2936 23/18639 0.304347826086957 1.93213185641512 0.057988720939817 0.370226771740209 GO:0001094 TFIID-class transcription factor complex binding 4/2936 10/18639 0.4 2.53937329700272 0.0583524980707597 0.370226771740209 GO:0030957 Tat protein binding 4/2936 10/18639 0.4 2.53937329700272 0.0583524980707597 0.370226771740209 GO:0033204 ribonuclease P RNA binding 4/2936 10/18639 0.4 2.53937329700272 0.0583524980707597 0.370226771740209 GO:0047429 nucleoside triphosphate diphosphatase activity 4/2936 10/18639 0.4 2.53937329700272 0.0583524980707597 0.370226771740209 GO:0050815 phosphoserine residue binding 4/2936 10/18639 0.4 2.53937329700272 0.0583524980707597 0.370226771740209 GO:0070097 delta-catenin binding 4/2936 10/18639 0.4 2.53937329700272 0.0583524980707597 0.370226771740209 GO:0070739 protein-glutamic acid ligase activity 4/2936 10/18639 0.4 2.53937329700272 0.0583524980707597 0.370226771740209 GO:0070740 tubulin-glutamic acid ligase activity 4/2936 10/18639 0.4 2.53937329700272 0.0583524980707597 0.370226771740209 GO:0097177 mitochondrial ribosome binding 4/2936 10/18639 0.4 2.53937329700272 0.0583524980707597 0.370226771740209 GO:0180051 translation factor activity 19/2936 84/18639 0.226190476190476 1.43595513818606 0.061725992674564 0.387236919412411 GO:0005507 copper ion binding 15/2936 63/18639 0.238095238095238 1.51153172440638 0.0619094806828435 0.387236919412411 GO:0097718 disordered domain specific binding 8/2936 28/18639 0.285714285714286 1.81383806928766 0.0619223536015255 0.387236919412411 GO:0019955 cytokine binding 30/2936 144/18639 0.208333333333333 1.32259025885559 0.0625302049746991 0.389176085247294 GO:0030296 protein tyrosine kinase activator activity 9/2936 33/18639 0.272727272727273 1.73139088432004 0.0641476377786674 0.394018717584053 GO:0019842 vitamin binding 31/2936 150/18639 0.206666666666667 1.31200953678474 0.0646751376866899 0.394018717584053 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 45/2936 229/18639 0.196506550218341 1.24750871577645 0.0650071046052372 0.394018717584053 GO:0008200 ion channel inhibitor activity 11/2936 43/18639 0.255813953488372 1.62401780622267 0.0654205000575722 0.394018717584053 GO:0048156 tau protein binding 11/2936 43/18639 0.255813953488372 1.62401780622267 0.0654205000575722 0.394018717584053 GO:0070003 threonine-type peptidase activity 6/2936 19/18639 0.315789473684211 2.00476839237057 0.0656061276573858 0.394018717584053 GO:0120227 acyl-CoA binding 6/2936 19/18639 0.315789473684211 2.00476839237057 0.0656061276573858 0.394018717584053 GO:0031491 nucleosome binding 17/2936 74/18639 0.22972972972973 1.45842385300832 0.0657200309359782 0.394018717584053 GO:0061135 endopeptidase regulator activity 37/2936 184/18639 0.201086956521739 1.27658711941713 0.0664894631338312 0.396811544821541 GO:0000287 magnesium ion binding 45/2936 230/18639 0.195652173913043 1.24208476483829 0.0689271451481239 0.409197200313333 GO:0008017 microtubule binding 53/2936 276/18639 0.192028985507246 1.21908319511906 0.0691909573597908 0.409197200313333 GO:0016247 channel regulator activity 34/2936 168/18639 0.202380952380952 1.28480196574543 0.0705460798267977 0.413760516081412 GO:0019888 protein phosphatase regulator activity 23/2936 107/18639 0.214953271028037 1.36461649137997 0.0705957116190933 0.413760516081412 GO:0004879 nuclear receptor activity 14/2936 59/18639 0.23728813559322 1.50640788805246 0.0713477215535254 0.416301214600257 GO:0004467 long-chain fatty acid-CoA ligase activity 5/2936 15/18639 0.333333333333333 2.11614441416894 0.0735107872793107 0.421397363921312 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 5/2936 15/18639 0.333333333333333 2.11614441416894 0.0735107872793107 0.421397363921312 GO:0048531 beta-1,3-galactosyltransferase activity 5/2936 15/18639 0.333333333333333 2.11614441416894 0.0735107872793107 0.421397363921312 GO:0140776 protein-containing complex destabilizing activity 5/2936 15/18639 0.333333333333333 2.11614441416894 0.0735107872793107 0.421397363921312 GO:0003785 actin monomer binding 8/2936 29/18639 0.275862068965517 1.7512919289674 0.0741770732492302 0.423359977016349 GO:0016248 channel inhibitor activity 11/2936 44/18639 0.25 1.5871083106267 0.0753321878452205 0.423789499753202 GO:0030020 extracellular matrix structural constituent conferring tensile strength 11/2936 44/18639 0.25 1.5871083106267 0.0753321878452205 0.423789499753202 GO:0097110 scaffold protein binding 16/2936 70/18639 0.228571428571429 1.45107045543013 0.0754391800621146 0.423789499753202 GO:0015035 protein-disulfide reductase activity 9/2936 34/18639 0.264705882352941 1.68046762301651 0.0755493140340444 0.423789499753202 GO:0042277 peptide binding 48/2936 249/18639 0.192771084337349 1.22379436000131 0.0762303848560999 0.424766072475274 GO:0005496 steroid binding 23/2936 108/18639 0.212962962962963 1.35198115349682 0.0768738794960161 0.424766072475274 GO:0017171 serine hydrolase activity 39/2936 198/18639 0.196969696969697 1.25044897200892 0.0786920163889368 0.424766072475274 GO:0003714 transcription corepressor activity 40/2936 204/18639 0.196078431372549 1.24479083186408 0.0801081497549518 0.424766072475274 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 14/2936 60/18639 0.233333333333333 1.48130108991826 0.0801532296864291 0.424766072475274 GO:0098531 ligand-modulated transcription factor activity 14/2936 60/18639 0.233333333333333 1.48130108991826 0.0801532296864291 0.424766072475274 GO:0002162 dystroglycan binding 4/2936 11/18639 0.363636363636364 2.30852117909339 0.0805983060243825 0.424766072475274 GO:0008432 JUN kinase binding 4/2936 11/18639 0.363636363636364 2.30852117909339 0.0805983060243825 0.424766072475274 GO:0019215 intermediate filament binding 4/2936 11/18639 0.363636363636364 2.30852117909339 0.0805983060243825 0.424766072475274 GO:0032794 GTPase activating protein binding 4/2936 11/18639 0.363636363636364 2.30852117909339 0.0805983060243825 0.424766072475274 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 4/2936 11/18639 0.363636363636364 2.30852117909339 0.0805983060243825 0.424766072475274 GO:0048407 platelet-derived growth factor binding 4/2936 11/18639 0.363636363636364 2.30852117909339 0.0805983060243825 0.424766072475274 GO:0050998 nitric-oxide synthase binding 4/2936 11/18639 0.363636363636364 2.30852117909339 0.0805983060243825 0.424766072475274 GO:0070990 snRNP binding 4/2936 11/18639 0.363636363636364 2.30852117909339 0.0805983060243825 0.424766072475274 GO:0097493 structural molecule activity conferring elasticity 4/2936 11/18639 0.363636363636364 2.30852117909339 0.0805983060243825 0.424766072475274 GO:0001972 retinoic acid binding 6/2936 20/18639 0.3 1.90452997275204 0.0817139530966125 0.428916211635633 GO:0004715 non-membrane spanning protein tyrosine kinase activity 11/2936 45/18639 0.244444444444444 1.55183923705722 0.0861414036303428 0.44855304599545 GO:0141110 transporter inhibitor activity 11/2936 45/18639 0.244444444444444 1.55183923705722 0.0861414036303428 0.44855304599545 GO:0016769 transferase activity, transferring nitrogenous groups 8/2936 30/18639 0.266666666666667 1.69291553133515 0.087789444144506 0.453822026015878 GO:0099106 ion channel regulator activity 32/2936 160/18639 0.2 1.26968664850136 0.0878477219449251 0.453822026015878 GO:1901681 sulfur compound binding 52/2936 275/18639 0.189090909090909 1.20043101312856 0.0884259483451633 0.455010686957199 GO:0051540 metal cluster binding 17/2936 77/18639 0.220779220779221 1.40160214444956 0.0892106693827257 0.457248411306755 GO:0004519 endonuclease activity 26/2936 127/18639 0.204724409448819 1.29967924649746 0.0926227831699109 0.47047178081558 GO:0000062 fatty-acyl-CoA binding 5/2936 16/18639 0.3125 1.98388538828338 0.0935904078133518 0.47047178081558 GO:0005324 long-chain fatty acid transmembrane transporter activity 5/2936 16/18639 0.3125 1.98388538828338 0.0935904078133518 0.47047178081558 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 5/2936 16/18639 0.3125 1.98388538828338 0.0935904078133518 0.47047178081558 GO:0070411 I-SMAD binding 5/2936 16/18639 0.3125 1.98388538828338 0.0935904078133518 0.47047178081558 GO:0005539 glycosaminoglycan binding 46/2936 242/18639 0.190082644628099 1.20672697998063 0.0970508707048151 0.485998038357063 GO:0031490 chromatin DNA binding 26/2936 128/18639 0.203125 1.2895255023842 0.0995731432403944 0.491573099550022 GO:0009931 calcium-dependent protein serine/threonine kinase activity 6/2936 21/18639 0.285714285714286 1.81383806928766 0.0998112854500171 0.491573099550022 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 6/2936 21/18639 0.285714285714286 1.81383806928766 0.0998112854500171 0.491573099550022 GO:0070182 DNA polymerase binding 6/2936 21/18639 0.285714285714286 1.81383806928766 0.0998112854500171 0.491573099550022 GO:0045505 dynein intermediate chain binding 9/2936 36/18639 0.25 1.5871083106267 0.101838014664197 0.491573099550022 GO:0043539 protein serine/threonine kinase activator activity 16/2936 73/18639 0.219178082191781 1.39143742301519 0.102131199692288 0.491573099550022 GO:0016853 isomerase activity 35/2936 180/18639 0.194444444444444 1.23441757493188 0.105257647326592 0.491573099550022 GO:0005548 phospholipid transporter activity 15/2936 68/18639 0.220588235294118 1.40038968584709 0.106298007229576 0.491573099550022 GO:0004859 phospholipase inhibitor activity 4/2936 12/18639 0.333333333333333 2.11614441416894 0.106371820478703 0.491573099550022 GO:0005025 transforming growth factor beta receptor activity, type I 4/2936 12/18639 0.333333333333333 2.11614441416894 0.106371820478703 0.491573099550022 GO:0005026 transforming growth factor beta receptor activity, type II 4/2936 12/18639 0.333333333333333 2.11614441416894 0.106371820478703 0.491573099550022 GO:0005049 nuclear export signal receptor activity 4/2936 12/18639 0.333333333333333 2.11614441416894 0.106371820478703 0.491573099550022 GO:0005165 neurotrophin receptor binding 4/2936 12/18639 0.333333333333333 2.11614441416894 0.106371820478703 0.491573099550022 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 4/2936 12/18639 0.333333333333333 2.11614441416894 0.106371820478703 0.491573099550022 GO:0016361 activin receptor activity, type I 4/2936 12/18639 0.333333333333333 2.11614441416894 0.106371820478703 0.491573099550022 GO:0016362 activin receptor activity, type II 4/2936 12/18639 0.333333333333333 2.11614441416894 0.106371820478703 0.491573099550022 GO:0016801 hydrolase activity, acting on ether bonds 4/2936 12/18639 0.333333333333333 2.11614441416894 0.106371820478703 0.491573099550022 GO:0016803 ether hydrolase activity 4/2936 12/18639 0.333333333333333 2.11614441416894 0.106371820478703 0.491573099550022 GO:0017002 activin receptor activity 4/2936 12/18639 0.333333333333333 2.11614441416894 0.106371820478703 0.491573099550022 GO:0035497 cAMP response element binding 4/2936 12/18639 0.333333333333333 2.11614441416894 0.106371820478703 0.491573099550022 GO:0045295 gamma-catenin binding 4/2936 12/18639 0.333333333333333 2.11614441416894 0.106371820478703 0.491573099550022 GO:0004518 nuclease activity 40/2936 209/18639 0.191387559808612 1.21501114689126 0.10643855177709 0.491573099550022 GO:0033293 monocarboxylic acid binding 17/2936 79/18639 0.215189873417722 1.3661185458559 0.107524118140074 0.494838107074212 GO:0005504 fatty acid binding 11/2936 47/18639 0.234042553191489 1.48580352484202 0.110463090076744 0.506579855194051 GO:0019894 kinesin binding 10/2936 42/18639 0.238095238095238 1.51153172440638 0.11376402500051 0.519893638726109 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 26/2936 130/18639 0.2 1.26968664850136 0.114462529485975 0.52126315692742 GO:0005092 GDP-dissociation inhibitor activity 5/2936 17/18639 0.294117647058824 1.86718624779612 0.116149566231807 0.52381228570342 GO:1901567 fatty acid derivative binding 5/2936 17/18639 0.294117647058824 1.86718624779612 0.116149566231807 0.52381228570342 GO:0004252 serine-type endopeptidase activity 34/2936 176/18639 0.193181818181818 1.22640187639336 0.116537419348536 0.52381228570342 GO:0044325 transmembrane transporter binding 27/2936 136/18639 0.198529411764706 1.26035071726238 0.116985667817904 0.52381228570342 GO:0002039 p53 binding 15/2936 69/18639 0.217391304347826 1.38009418315365 0.11702615717322 0.52381228570342 GO:0003712 transcription coregulator activity 88/2936 495/18639 0.177777777777778 1.12861035422343 0.117721965799522 0.525128359385583 GO:0005246 calcium channel regulator activity 12/2936 53/18639 0.226415094339623 1.43738111151098 0.119460389657646 0.527723796044903 GO:0051018 protein kinase A binding 12/2936 53/18639 0.226415094339623 1.43738111151098 0.119460389657646 0.527723796044903 GO:0016881 acid-amino acid ligase activity 6/2936 22/18639 0.272727272727273 1.73139088432004 0.119825955222429 0.527723796044903 GO:0001671 ATPase activator activity 7/2936 27/18639 0.259259259259259 1.64589009990917 0.120322640567239 0.527723796044903 GO:0035255 ionotropic glutamate receptor binding 7/2936 27/18639 0.259259259259259 1.64589009990917 0.120322640567239 0.527723796044903 GO:0008236 serine-type peptidase activity 37/2936 194/18639 0.190721649484536 1.21078365965336 0.120989916733209 0.528875656087975 GO:0070063 RNA polymerase binding 13/2936 59/18639 0.220338983050847 1.39880732462014 0.127319784882075 0.554689862802907 GO:0008375 acetylglucosaminyltransferase activity 10/2936 43/18639 0.232558139534884 1.47637982383879 0.128413578013522 0.557596499879313 GO:0008201 heparin binding 33/2936 172/18639 0.191860465116279 1.218013354667 0.128918997185967 0.557937514311455 GO:0043531 ADP binding 9/2936 38/18639 0.236842105263158 1.50357629427793 0.132693570442198 0.565088763957719 GO:0017022 myosin binding 16/2936 76/18639 0.210526315789474 1.33651226158038 0.133975678925214 0.565088763957719 GO:0051536 iron-sulfur cluster binding 16/2936 76/18639 0.210526315789474 1.33651226158038 0.133975678925214 0.565088763957719 GO:0019903 protein phosphatase binding 28/2936 144/18639 0.194444444444444 1.23441757493188 0.135220779751267 0.565088763957719 GO:0005542 folic acid binding 4/2936 13/18639 0.307692307692308 1.95336407461748 0.13532730154458 0.565088763957719 GO:0017154 semaphorin receptor activity 4/2936 13/18639 0.307692307692308 1.95336407461748 0.13532730154458 0.565088763957719 GO:0019104 DNA N-glycosylase activity 4/2936 13/18639 0.307692307692308 1.95336407461748 0.13532730154458 0.565088763957719 GO:0035325 Toll-like receptor binding 4/2936 13/18639 0.307692307692308 1.95336407461748 0.13532730154458 0.565088763957719 GO:0070123 transforming growth factor beta receptor activity, type III 4/2936 13/18639 0.307692307692308 1.95336407461748 0.13532730154458 0.565088763957719 GO:0097157 pre-mRNA intronic binding 4/2936 13/18639 0.307692307692308 1.95336407461748 0.13532730154458 0.565088763957719 GO:0140852 histone ubiquitin ligase activity 4/2936 13/18639 0.307692307692308 1.95336407461748 0.13532730154458 0.565088763957719 GO:0140297 DNA-binding transcription factor binding 86/2936 488/18639 0.176229508196721 1.11878126814669 0.139017074256835 0.578647503355677 GO:1901611 phosphatidylglycerol binding 5/2936 18/18639 0.277777777777778 1.76345367847411 0.141006798085974 0.585066301899581 GO:0004602 glutathione peroxidase activity 6/2936 23/18639 0.260869565217391 1.65611301978439 0.141650861439822 0.585878721208378 GO:0004197 cysteine-type endopeptidase activity 18/2936 88/18639 0.204545454545455 1.29854316324003 0.143492488403137 0.590099239283107 GO:0001223 transcription coactivator binding 10/2936 44/18639 0.227272727272727 1.44282573693337 0.144025751592434 0.590099239283107 GO:0030547 signaling receptor inhibitor activity 10/2936 44/18639 0.227272727272727 1.44282573693337 0.144025751592434 0.590099239283107 GO:0000217 DNA secondary structure binding 9/2936 39/18639 0.230769230769231 1.46502305596311 0.149756375663749 0.609095090089526 GO:0016776 phosphotransferase activity, phosphate group as acceptor 9/2936 39/18639 0.230769230769231 1.46502305596311 0.149756375663749 0.609095090089526 GO:1990782 protein tyrosine kinase binding 23/2936 117/18639 0.196581196581197 1.24798260322783 0.150207667790337 0.609095090089526 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 17/2936 83/18639 0.204819277108434 1.3002815075014 0.150526177581421 0.609095090089526 GO:0005006 epidermal growth factor receptor activity 11/2936 50/18639 0.22 1.3966553133515 0.153541168492523 0.618815100573487 GO:0003727 single-stranded RNA binding 18/2936 89/18639 0.202247191011236 1.28395279061936 0.154822140694361 0.618815100573487 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 18/2936 89/18639 0.202247191011236 1.28395279061936 0.154822140694361 0.618815100573487 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 18/2936 89/18639 0.202247191011236 1.28395279061936 0.154822140694361 0.618815100573487 GO:0030332 cyclin binding 8/2936 34/18639 0.235294117647059 1.4937489982369 0.155384411912371 0.619168982833746 GO:0019199 transmembrane receptor protein kinase activity 16/2936 78/18639 0.205128205128205 1.30224271641165 0.158005721855979 0.627700542449132 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 14/2936 67/18639 0.208955223880597 1.32653828947904 0.160443805436811 0.635454708199734 GO:0051117 ATPase binding 17/2936 84/18639 0.202380952380952 1.28480196574543 0.162567715178784 0.636838853118771 GO:0030552 cAMP binding 6/2936 24/18639 0.25 1.5871083106267 0.165149005256666 0.636838853118771 GO:0035035 histone acetyltransferase binding 6/2936 24/18639 0.25 1.5871083106267 0.165149005256666 0.636838853118771 GO:0050431 transforming growth factor beta binding 6/2936 24/18639 0.25 1.5871083106267 0.165149005256666 0.636838853118771 GO:0070300 phosphatidic acid binding 6/2936 24/18639 0.25 1.5871083106267 0.165149005256666 0.636838853118771 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 6/2936 24/18639 0.25 1.5871083106267 0.165149005256666 0.636838853118771 GO:0140793 histone H2AXY142 phosphatase activity 18/2936 90/18639 0.2 1.26968664850136 0.166623844865416 0.636838853118771 GO:0019992 diacylglycerol binding 4/2936 14/18639 0.285714285714286 1.81383806928766 0.167044015589583 0.636838853118771 GO:0061665 SUMO ligase activity 4/2936 14/18639 0.285714285714286 1.81383806928766 0.167044015589583 0.636838853118771 GO:0098821 BMP receptor activity 4/2936 14/18639 0.285714285714286 1.81383806928766 0.167044015589583 0.636838853118771 GO:1901612 cardiolipin binding 4/2936 14/18639 0.285714285714286 1.81383806928766 0.167044015589583 0.636838853118771 GO:0015245 fatty acid transmembrane transporter activity 5/2936 19/18639 0.263157894736842 1.67064032697548 0.167935608953327 0.636838853118771 GO:0043395 heparan sulfate proteoglycan binding 5/2936 19/18639 0.263157894736842 1.67064032697548 0.167935608953327 0.636838853118771 GO:0003743 translation initiation factor activity 11/2936 51/18639 0.215686274509804 1.36926991505049 0.169563826232083 0.636838853118771 GO:0005021 vascular endothelial growth factor receptor activity 11/2936 51/18639 0.215686274509804 1.36926991505049 0.169563826232083 0.636838853118771 GO:0005030 neurotrophin receptor activity 11/2936 51/18639 0.215686274509804 1.36926991505049 0.169563826232083 0.636838853118771 GO:0016597 amino acid binding 11/2936 51/18639 0.215686274509804 1.36926991505049 0.169563826232083 0.636838853118771 GO:0030544 Hsp70 protein binding 11/2936 51/18639 0.215686274509804 1.36926991505049 0.169563826232083 0.636838853118771 GO:0005154 epidermal growth factor receptor binding 8/2936 35/18639 0.228571428571429 1.45107045543013 0.175316526209619 0.654681999302778 GO:0016229 steroid dehydrogenase activity 8/2936 35/18639 0.228571428571429 1.45107045543013 0.175316526209619 0.654681999302778 GO:0140104 molecular carrier activity 45/2936 249/18639 0.180722891566265 1.14730721250123 0.176827648929916 0.657744491170528 GO:0016504 peptidase activator activity 12/2936 57/18639 0.210526315789474 1.33651226158038 0.177143122335138 0.657744491170528 GO:0003684 damaged DNA binding 15/2936 74/18639 0.202702702702703 1.28684457618381 0.179651815041684 0.66516975144329 GO:0031624 ubiquitin conjugating enzyme binding 7/2936 30/18639 0.233333333333333 1.48130108991826 0.182845890776605 0.666955129150334 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 9/2936 41/18639 0.219512195121951 1.39355851664784 0.186896318211813 0.666955129150334 GO:0016877 ligase activity, forming carbon-sulfur bonds 9/2936 41/18639 0.219512195121951 1.39355851664784 0.186896318211813 0.666955129150334 GO:0017080 sodium channel regulator activity 9/2936 41/18639 0.219512195121951 1.39355851664784 0.186896318211813 0.666955129150334 GO:0001848 complement binding 6/2936 25/18639 0.24 1.52362397820163 0.190158947036534 0.666955129150334 GO:0008483 transaminase activity 6/2936 25/18639 0.24 1.52362397820163 0.190158947036534 0.666955129150334 GO:0015645 fatty acid ligase activity 6/2936 25/18639 0.24 1.52362397820163 0.190158947036534 0.666955129150334 GO:0120515 fatty acid-CoA ligase activity 6/2936 25/18639 0.24 1.52362397820163 0.190158947036534 0.666955129150334 GO:0042826 histone deacetylase binding 24/2936 127/18639 0.188976377952756 1.19970391984381 0.194297831620358 0.666955129150334 GO:0004725 protein tyrosine phosphatase activity 19/2936 98/18639 0.193877551020408 1.23081868987377 0.194657399124679 0.666955129150334 GO:0044390 ubiquitin-like protein conjugating enzyme binding 8/2936 36/18639 0.222222222222222 1.41076294277929 0.196310386651168 0.666955129150334 GO:0061659 ubiquitin-like protein ligase activity 65/2936 372/18639 0.174731182795699 1.10926924936275 0.196779381361053 0.666955129150334 GO:0033192 calmodulin-dependent protein phosphatase activity 16/2936 81/18639 0.197530864197531 1.2540115046927 0.197993098395808 0.666955129150334 GO:0140791 histone H2AXS140 phosphatase activity 16/2936 81/18639 0.197530864197531 1.2540115046927 0.197993098395808 0.666955129150334 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 16/2936 81/18639 0.197530864197531 1.2540115046927 0.197993098395808 0.666955129150334 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 16/2936 81/18639 0.197530864197531 1.2540115046927 0.197993098395808 0.666955129150334 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 16/2936 81/18639 0.197530864197531 1.2540115046927 0.197993098395808 0.666955129150334 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 16/2936 81/18639 0.197530864197531 1.2540115046927 0.197993098395808 0.666955129150334 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 16/2936 81/18639 0.197530864197531 1.2540115046927 0.197993098395808 0.666955129150334 GO:1990439 MAP kinase serine/threonine phosphatase activity 16/2936 81/18639 0.197530864197531 1.2540115046927 0.197993098395808 0.666955129150334 GO:0000182 rDNA binding 3/2936 10/18639 0.3 1.90452997275204 0.199647130313528 0.666955129150334 GO:0005031 tumor necrosis factor receptor activity 3/2936 10/18639 0.3 1.90452997275204 0.199647130313528 0.666955129150334 GO:0005381 iron ion transmembrane transporter activity 3/2936 10/18639 0.3 1.90452997275204 0.199647130313528 0.666955129150334 GO:0005522 profilin binding 3/2936 10/18639 0.3 1.90452997275204 0.199647130313528 0.666955129150334 GO:0015279 store-operated calcium channel activity 3/2936 10/18639 0.3 1.90452997275204 0.199647130313528 0.666955129150334 GO:0015643 toxic substance binding 3/2936 10/18639 0.3 1.90452997275204 0.199647130313528 0.666955129150334 GO:0015658 branched-chain amino acid transmembrane transporter activity 3/2936 10/18639 0.3 1.90452997275204 0.199647130313528 0.666955129150334 GO:0016175 superoxide-generating NAD(P)H oxidase activity 3/2936 10/18639 0.3 1.90452997275204 0.199647130313528 0.666955129150334 GO:0016868 intramolecular phosphotransferase activity 3/2936 10/18639 0.3 1.90452997275204 0.199647130313528 0.666955129150334 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 3/2936 10/18639 0.3 1.90452997275204 0.199647130313528 0.666955129150334 GO:0019911 structural constituent of myelin sheath 3/2936 10/18639 0.3 1.90452997275204 0.199647130313528 0.666955129150334 GO:0031419 cobalamin binding 3/2936 10/18639 0.3 1.90452997275204 0.199647130313528 0.666955129150334 GO:0031957 very long-chain fatty acid-CoA ligase activity 3/2936 10/18639 0.3 1.90452997275204 0.199647130313528 0.666955129150334 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 3/2936 10/18639 0.3 1.90452997275204 0.199647130313528 0.666955129150334 GO:1990757 ubiquitin ligase activator activity 3/2936 10/18639 0.3 1.90452997275204 0.199647130313528 0.666955129150334 GO:0000774 adenyl-nucleotide exchange factor activity 4/2936 15/18639 0.266666666666667 1.69291553133515 0.201056098611501 0.666955129150334 GO:0005523 tropomyosin binding 4/2936 15/18639 0.266666666666667 1.69291553133515 0.201056098611501 0.666955129150334 GO:0008242 omega peptidase activity 4/2936 15/18639 0.266666666666667 1.69291553133515 0.201056098611501 0.666955129150334 GO:0015929 hexosaminidase activity 4/2936 15/18639 0.266666666666667 1.69291553133515 0.201056098611501 0.666955129150334 GO:0045504 dynein heavy chain binding 4/2936 15/18639 0.266666666666667 1.69291553133515 0.201056098611501 0.666955129150334 GO:0050700 CARD domain binding 4/2936 15/18639 0.266666666666667 1.69291553133515 0.201056098611501 0.666955129150334 GO:0005544 calcium-dependent phospholipid binding 11/2936 53/18639 0.207547169811321 1.3175993522184 0.203879023121622 0.671208773853803 GO:0016860 intramolecular oxidoreductase activity 11/2936 53/18639 0.207547169811321 1.3175993522184 0.203879023121622 0.671208773853803 GO:0038064 collagen receptor activity 11/2936 53/18639 0.207547169811321 1.3175993522184 0.203879023121622 0.671208773853803 GO:0003924 GTPase activity 58/2936 331/18639 0.175226586102719 1.11241428418548 0.205569716738137 0.67507442154961 GO:0017147 Wnt-protein binding 7/2936 31/18639 0.225806451612903 1.43351718379186 0.206206888999551 0.675469684016073 GO:0008307 structural constituent of muscle 9/2936 42/18639 0.214285714285714 1.36037855196575 0.206841489087622 0.675854565593806 GO:0015459 potassium channel regulator activity 12/2936 59/18639 0.203389830508475 1.29120676118783 0.210218537261185 0.683471711941217 GO:0045309 protein phosphorylated amino acid binding 12/2936 59/18639 0.203389830508475 1.29120676118783 0.210218537261185 0.683471711941217 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 16/2936 82/18639 0.195121951219512 1.23871868146474 0.212296542744804 0.686810844968958 GO:0033549 MAP kinase phosphatase activity 16/2936 82/18639 0.195121951219512 1.23871868146474 0.212296542744804 0.686810844968958 GO:0016879 ligase activity, forming carbon-nitrogen bonds 10/2936 48/18639 0.208333333333333 1.32259025885559 0.215251626970064 0.688481824918583 GO:0140693 molecular condensate scaffold activity 10/2936 48/18639 0.208333333333333 1.32259025885559 0.215251626970064 0.688481824918583 GO:0120013 lipid transfer activity 13/2936 65/18639 0.2 1.26968664850136 0.215526300948732 0.688481824918583 GO:0005112 Notch binding 6/2936 26/18639 0.230769230769231 1.46502305596311 0.21650040554058 0.688481824918583 GO:0005227 calcium-activated cation channel activity 6/2936 26/18639 0.230769230769231 1.46502305596311 0.21650040554058 0.688481824918583 GO:0034237 protein kinase A regulatory subunit binding 6/2936 26/18639 0.230769230769231 1.46502305596311 0.21650040554058 0.688481824918583 GO:0051139 metal cation:proton antiporter activity 6/2936 26/18639 0.230769230769231 1.46502305596311 0.21650040554058 0.688481824918583 GO:0005543 phospholipid binding 85/2936 497/18639 0.17102615694165 1.08574814006656 0.217447423768751 0.689815006955723 GO:0022829 wide pore channel activity 8/2936 37/18639 0.216216216216216 1.37263421459607 0.21826983228594 0.690747386919428 GO:0051020 GTPase binding 55/2936 315/18639 0.174603174603175 1.10845659789801 0.221023280632213 0.692597840183294 GO:0003925 G protein activity 11/2936 54/18639 0.203703703703704 1.29319936421435 0.22207586846592 0.692597840183294 GO:0140463 chromatin-protein adaptor activity 11/2936 54/18639 0.203703703703704 1.29319936421435 0.22207586846592 0.692597840183294 GO:0005123 death receptor binding 5/2936 21/18639 0.238095238095238 1.51153172440638 0.226946434485424 0.692597840183294 GO:0009975 cyclase activity 5/2936 21/18639 0.238095238095238 1.51153172440638 0.226946434485424 0.692597840183294 GO:0010314 phosphatidylinositol-5-phosphate binding 5/2936 21/18639 0.238095238095238 1.51153172440638 0.226946434485424 0.692597840183294 GO:0004714 transmembrane receptor protein tyrosine kinase activity 12/2936 60/18639 0.2 1.26968664850136 0.22768170824137 0.692597840183294 GO:0140789 histone phosphatase activity 25/2936 136/18639 0.183823529411765 1.16699140487258 0.229758473955253 0.692597840183294 GO:0008378 galactosyltransferase activity 7/2936 32/18639 0.21875 1.38871977179837 0.230614863688426 0.692597840183294 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 7/2936 32/18639 0.21875 1.38871977179837 0.230614863688426 0.692597840183294 GO:0140142 nucleocytoplasmic carrier activity 7/2936 32/18639 0.21875 1.38871977179837 0.230614863688426 0.692597840183294 GO:0005004 GPI-linked ephrin receptor activity 10/2936 49/18639 0.204081632653061 1.29559862091976 0.234975258641719 0.692597840183294 GO:0005008 hepatocyte growth factor receptor activity 10/2936 49/18639 0.204081632653061 1.29559862091976 0.234975258641719 0.692597840183294 GO:0005009 insulin receptor activity 10/2936 49/18639 0.204081632653061 1.29559862091976 0.234975258641719 0.692597840183294 GO:0005011 macrophage colony-stimulating factor receptor activity 10/2936 49/18639 0.204081632653061 1.29559862091976 0.234975258641719 0.692597840183294 GO:0005018 platelet-derived growth factor alpha-receptor activity 10/2936 49/18639 0.204081632653061 1.29559862091976 0.234975258641719 0.692597840183294 GO:0005020 stem cell factor receptor activity 10/2936 49/18639 0.204081632653061 1.29559862091976 0.234975258641719 0.692597840183294 GO:0008288 boss receptor activity 10/2936 49/18639 0.204081632653061 1.29559862091976 0.234975258641719 0.692597840183294 GO:0036332 placental growth factor receptor activity 10/2936 49/18639 0.204081632653061 1.29559862091976 0.234975258641719 0.692597840183294 GO:0038062 protein tyrosine kinase collagen receptor activity 10/2936 49/18639 0.204081632653061 1.29559862091976 0.234975258641719 0.692597840183294 GO:0060175 brain-derived neurotrophic factor receptor activity 10/2936 49/18639 0.204081632653061 1.29559862091976 0.234975258641719 0.692597840183294 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 4/2936 16/18639 0.25 1.5871083106267 0.236877995544217 0.692597840183294 GO:0005024 transforming growth factor beta receptor activity 4/2936 16/18639 0.25 1.5871083106267 0.236877995544217 0.692597840183294 GO:0005159 insulin-like growth factor receptor binding 4/2936 16/18639 0.25 1.5871083106267 0.236877995544217 0.692597840183294 GO:0005521 lamin binding 4/2936 16/18639 0.25 1.5871083106267 0.236877995544217 0.692597840183294 GO:0008296 3'-5'-DNA exonuclease activity 4/2936 16/18639 0.25 1.5871083106267 0.236877995544217 0.692597840183294 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 4/2936 16/18639 0.25 1.5871083106267 0.236877995544217 0.692597840183294 GO:0055102 lipase inhibitor activity 4/2936 16/18639 0.25 1.5871083106267 0.236877995544217 0.692597840183294 GO:0017018 myosin phosphatase activity 16/2936 84/18639 0.19047619047619 1.20922537952511 0.242219429911258 0.692597840183294 GO:0004683 calcium/calmodulin-dependent protein kinase activity 6/2936 27/18639 0.222222222222222 1.41076294277929 0.243979766961534 0.692597840183294 GO:0008320 protein transmembrane transporter activity 6/2936 27/18639 0.222222222222222 1.41076294277929 0.243979766961534 0.692597840183294 GO:0016405 CoA-ligase activity 6/2936 27/18639 0.222222222222222 1.41076294277929 0.243979766961534 0.692597840183294 GO:0000099 sulfur amino acid transmembrane transporter activity 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0008172 S-methyltransferase activity 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0008199 ferric iron binding 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0008526 phosphatidylinositol transfer activity 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0010854 adenylate cyclase regulator activity 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0015173 aromatic amino acid transmembrane transporter activity 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0019107 myristoyltransferase activity 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0034713 type I transforming growth factor beta receptor binding 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0045294 alpha-catenin binding 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0047676 arachidonate-CoA ligase activity 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0048185 activin binding 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0070697 activin receptor binding 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0140537 transcription regulator activator activity 3/2936 11/18639 0.272727272727273 1.73139088432004 0.244290439421958 0.692597840183294 GO:0019205 nucleobase-containing compound kinase activity 9/2936 44/18639 0.204545454545455 1.29854316324003 0.249092807120287 0.704684629667132 GO:0005007 fibroblast growth factor receptor activity 10/2936 50/18639 0.2 1.26968664850136 0.255333781179018 0.716140025753167 GO:0005017 platelet-derived growth factor receptor activity 10/2936 50/18639 0.2 1.26968664850136 0.255333781179018 0.716140025753167 GO:0005019 platelet-derived growth factor beta-receptor activity 10/2936 50/18639 0.2 1.26968664850136 0.255333781179018 0.716140025753167 GO:0032813 tumor necrosis factor receptor superfamily binding 10/2936 50/18639 0.2 1.26968664850136 0.255333781179018 0.716140025753167 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 5/2936 22/18639 0.227272727272727 1.44282573693337 0.258452457798069 0.720250239535343 GO:0070034 telomerase RNA binding 5/2936 22/18639 0.227272727272727 1.44282573693337 0.258452457798069 0.720250239535343 GO:0140517 protein-RNA adaptor activity 5/2936 22/18639 0.227272727272727 1.44282573693337 0.258452457798069 0.720250239535343 GO:0042393 histone binding 43/2936 247/18639 0.174089068825911 1.10519283169147 0.259982148570241 0.722971634428308 GO:0004722 protein serine/threonine phosphatase activity 19/2936 103/18639 0.184466019417476 1.17107020978281 0.262380573238159 0.728092163953874 GO:0140303 intramembrane lipid transporter activity 9/2936 45/18639 0.2 1.26968664850136 0.271224974719244 0.746960374848123 GO:0019789 SUMO transferase activity 6/2936 28/18639 0.214285714285714 1.36037855196575 0.272395320799459 0.746960374848123 GO:0046875 ephrin receptor binding 6/2936 28/18639 0.214285714285714 1.36037855196575 0.272395320799459 0.746960374848123 GO:0051537 2 iron, 2 sulfur cluster binding 6/2936 28/18639 0.214285714285714 1.36037855196575 0.272395320799459 0.746960374848123 GO:0051959 dynein light intermediate chain binding 6/2936 28/18639 0.214285714285714 1.36037855196575 0.272395320799459 0.746960374848123 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 4/2936 17/18639 0.235294117647059 1.4937489982369 0.27402520456342 0.746960374848123 GO:0019198 transmembrane receptor protein phosphatase activity 4/2936 17/18639 0.235294117647059 1.4937489982369 0.27402520456342 0.746960374848123 GO:0038191 neuropilin binding 4/2936 17/18639 0.235294117647059 1.4937489982369 0.27402520456342 0.746960374848123 GO:0022804 active transmembrane transporter activity 77/2936 457/18639 0.168490153172867 1.06964848943769 0.27557657653241 0.746960374848123 GO:0005010 insulin-like growth factor receptor activity 10/2936 51/18639 0.196078431372549 1.24479083186408 0.276253282385587 0.746960374848123 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 22/2936 122/18639 0.180327868852459 1.14479943717336 0.278270955338972 0.746960374848123 GO:0061630 ubiquitin protein ligase activity 60/2936 353/18639 0.169971671388102 1.07905380892467 0.27913134340999 0.746960374848123 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 7/2936 34/18639 0.205882352941176 1.30703037345728 0.281993147487756 0.746960374848123 GO:0016831 carboxy-lyase activity 7/2936 34/18639 0.205882352941176 1.30703037345728 0.281993147487756 0.746960374848123 GO:0003713 transcription coactivator activity 44/2936 256/18639 0.171875 1.09113696355586 0.287121553857732 0.746960374848123 GO:0003725 double-stranded RNA binding 14/2936 75/18639 0.186666666666667 1.18504087193461 0.287431916623505 0.746960374848123 GO:0044183 protein folding chaperone 14/2936 75/18639 0.186666666666667 1.18504087193461 0.287431916623505 0.746960374848123 GO:0004532 RNA exonuclease activity 8/2936 40/18639 0.2 1.26968664850136 0.28886411028077 0.746960374848123 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 8/2936 40/18639 0.2 1.26968664850136 0.28886411028077 0.746960374848123 GO:0071949 FAD binding 8/2936 40/18639 0.2 1.26968664850136 0.28886411028077 0.746960374848123 GO:0030971 receptor tyrosine kinase binding 15/2936 81/18639 0.185185185185185 1.17563578564941 0.288867223773647 0.746960374848123 GO:0000340 RNA 7-methylguanosine cap binding 3/2936 12/18639 0.25 1.5871083106267 0.290263312403043 0.746960374848123 GO:0004126 cytidine deaminase activity 3/2936 12/18639 0.25 1.5871083106267 0.290263312403043 0.746960374848123 GO:0015269 calcium-activated potassium channel activity 3/2936 12/18639 0.25 1.5871083106267 0.290263312403043 0.746960374848123 GO:0016840 carbon-nitrogen lyase activity 3/2936 12/18639 0.25 1.5871083106267 0.290263312403043 0.746960374848123 GO:0031543 peptidyl-proline dioxygenase activity 3/2936 12/18639 0.25 1.5871083106267 0.290263312403043 0.746960374848123 GO:0035259 nuclear glucocorticoid receptor binding 3/2936 12/18639 0.25 1.5871083106267 0.290263312403043 0.746960374848123 GO:0042301 phosphate ion binding 3/2936 12/18639 0.25 1.5871083106267 0.290263312403043 0.746960374848123 GO:0043047 single-stranded telomeric DNA binding 3/2936 12/18639 0.25 1.5871083106267 0.290263312403043 0.746960374848123 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 3/2936 12/18639 0.25 1.5871083106267 0.290263312403043 0.746960374848123 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 3/2936 12/18639 0.25 1.5871083106267 0.290263312403043 0.746960374848123 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 3/2936 12/18639 0.25 1.5871083106267 0.290263312403043 0.746960374848123 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 3/2936 12/18639 0.25 1.5871083106267 0.290263312403043 0.746960374848123 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/2936 12/18639 0.25 1.5871083106267 0.290263312403043 0.746960374848123 GO:1990817 poly(A) RNA polymerase activity 3/2936 12/18639 0.25 1.5871083106267 0.290263312403043 0.746960374848123 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 5/2936 23/18639 0.217391304347826 1.38009418315365 0.290897345675359 0.746960374848123 GO:0005212 structural constituent of eye lens 5/2936 23/18639 0.217391304347826 1.38009418315365 0.290897345675359 0.746960374848123 GO:0016849 phosphorus-oxygen lyase activity 5/2936 23/18639 0.217391304347826 1.38009418315365 0.290897345675359 0.746960374848123 GO:0005319 lipid transporter activity 31/2936 178/18639 0.174157303370787 1.10562601414444 0.299479869975851 0.765272828606093 GO:0019787 ubiquitin-like protein transferase activity 80/2936 479/18639 0.167014613778706 1.06028112609717 0.299980374897721 0.765272828606093 GO:0008408 3'-5' exonuclease activity 11/2936 58/18639 0.189655172413793 1.20401320116508 0.300465411993726 0.765272828606093 GO:0004175 endopeptidase activity 68/2936 405/18639 0.167901234567901 1.0659097789888 0.300849129286367 0.765272828606093 GO:0035250 UDP-galactosyltransferase activity 6/2936 29/18639 0.206896551724138 1.31346894672555 0.301542086252592 0.765272828606093 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 6/2936 29/18639 0.206896551724138 1.31346894672555 0.301542086252592 0.765272828606093 GO:0016798 hydrolase activity, acting on glycosyl bonds 23/2936 130/18639 0.176923076923077 1.12318434290505 0.305331573240185 0.773388306637445 GO:0000175 3'-5'-RNA exonuclease activity 7/2936 35/18639 0.2 1.26968664850136 0.308662302807291 0.778289724940778 GO:0000400 four-way junction DNA binding 4/2936 18/18639 0.222222222222222 1.41076294277929 0.312030463556976 0.778289724940778 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 4/2936 18/18639 0.222222222222222 1.41076294277929 0.312030463556976 0.778289724940778 GO:0008308 voltage-gated monoatomic anion channel activity 4/2936 18/18639 0.222222222222222 1.41076294277929 0.312030463556976 0.778289724940778 GO:0031690 adrenergic receptor binding 4/2936 18/18639 0.222222222222222 1.41076294277929 0.312030463556976 0.778289724940778 GO:0032393 MHC class I receptor activity 4/2936 18/18639 0.222222222222222 1.41076294277929 0.312030463556976 0.778289724940778 GO:0050811 GABA receptor binding 4/2936 18/18639 0.222222222222222 1.41076294277929 0.312030463556976 0.778289724940778 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 4/2936 18/18639 0.222222222222222 1.41076294277929 0.312030463556976 0.778289724940778 GO:0001530 lipopolysaccharide binding 8/2936 41/18639 0.195121951219512 1.23871868146474 0.31358357502476 0.779189605622359 GO:0042169 SH2 domain binding 8/2936 41/18639 0.195121951219512 1.23871868146474 0.31358357502476 0.779189605622359 GO:0005003 ephrin receptor activity 10/2936 53/18639 0.188679245283019 1.19781759292581 0.319465683261448 0.790798575800592 GO:0005005 transmembrane-ephrin receptor activity 10/2936 53/18639 0.188679245283019 1.19781759292581 0.319465683261448 0.790798575800592 GO:0070888 E-box binding 11/2936 59/18639 0.186440677966102 1.18360619775551 0.321146987453266 0.793457679775839 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 5/2936 24/18639 0.208333333333333 1.32259025885559 0.323989014206595 0.795965491669209 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 5/2936 24/18639 0.208333333333333 1.32259025885559 0.323989014206595 0.795965491669209 GO:0060229 lipase activator activity 5/2936 24/18639 0.208333333333333 1.32259025885559 0.323989014206595 0.795965491669209 GO:0140375 immune receptor activity 27/2936 156/18639 0.173076923076923 1.09876729197233 0.328016374130596 0.804347844256453 GO:0022839 monoatomic ion-gated channel activity 6/2936 30/18639 0.2 1.26968664850136 0.331216135121588 0.804615281843474 GO:0033612 receptor serine/threonine kinase binding 6/2936 30/18639 0.2 1.26968664850136 0.331216135121588 0.804615281843474 GO:0016755 aminoacyltransferase activity 82/2936 496/18639 0.165322580645161 1.04953936670476 0.332831873734109 0.804615281843474 GO:0002161 aminoacyl-tRNA editing activity 3/2936 13/18639 0.230769230769231 1.46502305596311 0.336744115660582 0.804615281843474 GO:0005035 death receptor activity 3/2936 13/18639 0.230769230769231 1.46502305596311 0.336744115660582 0.804615281843474 GO:0031432 titin binding 3/2936 13/18639 0.230769230769231 1.46502305596311 0.336744115660582 0.804615281843474 GO:0043560 insulin receptor substrate binding 3/2936 13/18639 0.230769230769231 1.46502305596311 0.336744115660582 0.804615281843474 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 3/2936 13/18639 0.230769230769231 1.46502305596311 0.336744115660582 0.804615281843474 GO:0045159 myosin II binding 3/2936 13/18639 0.230769230769231 1.46502305596311 0.336744115660582 0.804615281843474 GO:0070700 BMP receptor binding 3/2936 13/18639 0.230769230769231 1.46502305596311 0.336744115660582 0.804615281843474 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 3/2936 13/18639 0.230769230769231 1.46502305596311 0.336744115660582 0.804615281843474 GO:0089720 caspase binding 3/2936 13/18639 0.230769230769231 1.46502305596311 0.336744115660582 0.804615281843474 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 3/2936 13/18639 0.230769230769231 1.46502305596311 0.336744115660582 0.804615281843474 GO:1901338 catecholamine binding 3/2936 13/18639 0.230769230769231 1.46502305596311 0.336744115660582 0.804615281843474 GO:0030246 carbohydrate binding 47/2936 280/18639 0.167857142857143 1.0656298657065 0.340488240851041 0.812076881007865 GO:0001098 basal transcription machinery binding 11/2936 60/18639 0.183333333333333 1.16387942779292 0.342128988908998 0.8130228881892 GO:0001099 basal RNA polymerase II transcription machinery binding 11/2936 60/18639 0.183333333333333 1.16387942779292 0.342128988908998 0.8130228881892 GO:0070851 growth factor receptor binding 24/2936 139/18639 0.172661870503597 1.09613235841844 0.345521906573051 0.819595520673281 GO:0008301 DNA binding, bending 4/2936 19/18639 0.210526315789474 1.33651226158038 0.350455758117949 0.826797248845054 GO:0050145 nucleoside monophosphate kinase activity 4/2936 19/18639 0.210526315789474 1.33651226158038 0.350455758117949 0.826797248845054 GO:0097001 ceramide binding 4/2936 19/18639 0.210526315789474 1.33651226158038 0.350455758117949 0.826797248845054 GO:0003707 nuclear steroid receptor activity 5/2936 25/18639 0.2 1.26968664850136 0.35744653099911 0.841770479307814 GO:0016500 protein-hormone receptor activity 12/2936 67/18639 0.17910447761194 1.13703281955346 0.362464911503701 0.850195491134631 GO:0030280 structural constituent of skin epidermis 7/2936 37/18639 0.189189189189189 1.20105493777156 0.363201173842084 0.850195491134631 GO:0030551 cyclic nucleotide binding 7/2936 37/18639 0.189189189189189 1.20105493777156 0.363201173842084 0.850195491134631 GO:0004712 protein serine/threonine/tyrosine kinase activity 8/2936 43/18639 0.186046511627907 1.18110385907103 0.364093083713786 0.850195491134631 GO:0035254 glutamate receptor binding 9/2936 49/18639 0.183673469387755 1.16603875882778 0.364276568504509 0.850195491134631 GO:0050660 flavin adenine dinucleotide binding 15/2936 86/18639 0.174418604651163 1.1072848678791 0.3769372472788 0.874366514440146 GO:0005545 1-phosphatidylinositol binding 3/2936 14/18639 0.214285714285714 1.36037855196575 0.383025961134489 0.874366514440146 GO:0008494 translation activator activity 3/2936 14/18639 0.214285714285714 1.36037855196575 0.383025961134489 0.874366514440146 GO:0042813 Wnt receptor activity 3/2936 14/18639 0.214285714285714 1.36037855196575 0.383025961134489 0.874366514440146 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 3/2936 14/18639 0.214285714285714 1.36037855196575 0.383025961134489 0.874366514440146 GO:0071933 Arp2/3 complex binding 3/2936 14/18639 0.214285714285714 1.36037855196575 0.383025961134489 0.874366514440146 GO:0098847 sequence-specific single stranded DNA binding 3/2936 14/18639 0.214285714285714 1.36037855196575 0.383025961134489 0.874366514440146 GO:0001664 G protein-coupled receptor binding 49/2936 297/18639 0.164983164983165 1.04738460903311 0.385153943072332 0.874366514440146 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 4/2936 20/18639 0.2 1.26968664850136 0.388900657421046 0.874366514440146 GO:0016004 phospholipase activator activity 4/2936 20/18639 0.2 1.26968664850136 0.388900657421046 0.874366514440146 GO:0016505 peptidase activator activity involved in apoptotic process 4/2936 20/18639 0.2 1.26968664850136 0.388900657421046 0.874366514440146 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 4/2936 20/18639 0.2 1.26968664850136 0.388900657421046 0.874366514440146 GO:0031418 L-ascorbic acid binding 4/2936 20/18639 0.2 1.26968664850136 0.388900657421046 0.874366514440146 GO:0005109 frizzled binding 7/2936 38/18639 0.184210526315789 1.16944822888283 0.390774626598579 0.874366514440146 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 7/2936 38/18639 0.184210526315789 1.16944822888283 0.390774626598579 0.874366514440146 GO:0004112 cyclic-nucleotide phosphodiesterase activity 5/2936 26/18639 0.192307692307692 1.22085254663593 0.39100513229876 0.874366514440146 GO:0005160 transforming growth factor beta receptor binding 5/2936 26/18639 0.192307692307692 1.22085254663593 0.39100513229876 0.874366514440146 GO:0008198 ferrous iron binding 5/2936 26/18639 0.192307692307692 1.22085254663593 0.39100513229876 0.874366514440146 GO:0030507 spectrin binding 5/2936 26/18639 0.192307692307692 1.22085254663593 0.39100513229876 0.874366514440146 GO:0050750 low-density lipoprotein particle receptor binding 5/2936 26/18639 0.192307692307692 1.22085254663593 0.39100513229876 0.874366514440146 GO:0097602 cullin family protein binding 5/2936 26/18639 0.192307692307692 1.22085254663593 0.39100513229876 0.874366514440146 GO:0120014 phospholipid transfer activity 5/2936 26/18639 0.192307692307692 1.22085254663593 0.39100513229876 0.874366514440146 GO:0022884 macromolecule transmembrane transporter activity 6/2936 32/18639 0.1875 1.19033123297003 0.391357621229905 0.874366514440146 GO:0043425 bHLH transcription factor binding 6/2936 32/18639 0.1875 1.19033123297003 0.391357621229905 0.874366514440146 GO:0120015 sterol transfer activity 6/2936 32/18639 0.1875 1.19033123297003 0.391357621229905 0.874366514440146 GO:0051219 phosphoprotein binding 16/2936 93/18639 0.172043010752688 1.09220356860332 0.392435361127446 0.875278185995857 GO:0004842 ubiquitin-protein transferase activity 73/2936 449/18639 0.162583518930958 1.03215061626503 0.402823645137646 0.896917383636972 GO:0008013 beta-catenin binding 18/2936 106/18639 0.169811320754717 1.07803583363323 0.403852018847954 0.897677871826999 GO:0016410 N-acyltransferase activity 16/2936 94/18639 0.170212765957447 1.08058438170329 0.410006456948786 0.908268541071294 GO:0042562 hormone binding 16/2936 94/18639 0.170212765957447 1.08058438170329 0.410006456948786 0.908268541071294 GO:0016830 carbon-carbon lyase activity 9/2936 51/18639 0.176470588235294 1.12031174867767 0.412177458144627 0.911532889670096 GO:0004721 phosphoprotein phosphatase activity 29/2936 175/18639 0.165714285714286 1.05202608018684 0.414044523010045 0.913698243609015 GO:0005126 cytokine receptor binding 45/2936 275/18639 0.163636363636364 1.03883453059202 0.41494023522723 0.913698243609015 GO:0051539 4 iron, 4 sulfur cluster binding 8/2936 45/18639 0.177777777777778 1.12861035422343 0.415253830683822 0.913698243609015 GO:0019239 deaminase activity 6/2936 33/18639 0.181818181818182 1.15426058954669 0.421453394146642 0.916650709954443 GO:0071889 14-3-3 protein binding 6/2936 33/18639 0.181818181818182 1.15426058954669 0.421453394146642 0.916650709954443 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 22/2936 132/18639 0.166666666666667 1.05807220708447 0.422384885487656 0.916650709954443 GO:0004364 glutathione transferase activity 5/2936 27/18639 0.185185185185185 1.17563578564941 0.424419988057221 0.916650709954443 GO:0008266 poly(U) RNA binding 5/2936 27/18639 0.185185185185185 1.17563578564941 0.424419988057221 0.916650709954443 GO:0001846 opsonin binding 4/2936 21/18639 0.19047619047619 1.20922537952511 0.427007533405897 0.916650709954443 GO:0019200 carbohydrate kinase activity 4/2936 21/18639 0.19047619047619 1.20922537952511 0.427007533405897 0.916650709954443 GO:0051010 microtubule plus-end binding 4/2936 21/18639 0.19047619047619 1.20922537952511 0.427007533405897 0.916650709954443 GO:0004867 serine-type endopeptidase inhibitor activity 16/2936 95/18639 0.168421052631579 1.06920980926431 0.42762186864841 0.916650709954443 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 3/2936 15/18639 0.2 1.26968664850136 0.428518426765237 0.916650709954443 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 3/2936 15/18639 0.2 1.26968664850136 0.428518426765237 0.916650709954443 GO:0004865 protein serine/threonine phosphatase inhibitor activity 3/2936 15/18639 0.2 1.26968664850136 0.428518426765237 0.916650709954443 GO:0005041 low-density lipoprotein particle receptor activity 3/2936 15/18639 0.2 1.26968664850136 0.428518426765237 0.916650709954443 GO:0008252 nucleotidase activity 3/2936 15/18639 0.2 1.26968664850136 0.428518426765237 0.916650709954443 GO:0016846 carbon-sulfur lyase activity 3/2936 15/18639 0.2 1.26968664850136 0.428518426765237 0.916650709954443 GO:0031005 filamin binding 3/2936 15/18639 0.2 1.26968664850136 0.428518426765237 0.916650709954443 GO:0120283 protein serine/threonine kinase binding 3/2936 15/18639 0.2 1.26968664850136 0.428518426765237 0.916650709954443 GO:0004896 cytokine receptor activity 16/2936 96/18639 0.166666666666667 1.05807220708447 0.445246304636814 0.949345484089734 GO:0140662 ATP-dependent protein folding chaperone 7/2936 40/18639 0.175 1.11097581743869 0.445831445471436 0.949345484089734 GO:0001217 DNA-binding transcription repressor activity 45/2936 278/18639 0.161870503597122 1.02762408601729 0.445981734683318 0.949345484089734 GO:0038024 cargo receptor activity 11/2936 65/18639 0.169230769230769 1.07435024103961 0.449186971176098 0.950663140274064 GO:0008376 acetylgalactosaminyltransferase activity 6/2936 34/18639 0.176470588235294 1.12031174867767 0.451337732716403 0.950663140274064 GO:0052866 phosphatidylinositol phosphate phosphatase activity 6/2936 34/18639 0.176470588235294 1.12031174867767 0.451337732716403 0.950663140274064 GO:0036002 pre-mRNA binding 10/2936 59/18639 0.169491525423729 1.07600563432319 0.454381979608938 0.950663140274064 GO:0016866 intramolecular transferase activity 5/2936 28/18639 0.178571428571429 1.13364879330479 0.457468828765429 0.950663140274064 GO:0046625 sphingolipid binding 5/2936 28/18639 0.178571428571429 1.13364879330479 0.457468828765429 0.950663140274064 GO:0034212 protein N-acetyltransferase activity 9/2936 53/18639 0.169811320754717 1.07803583363323 0.460013490338945 0.950663140274064 GO:0008970 phospholipase A1 activity 4/2936 22/18639 0.181818181818182 1.15426058954669 0.464464216874304 0.950663140274064 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/2936 22/18639 0.181818181818182 1.15426058954669 0.464464216874304 0.950663140274064 GO:0033691 sialic acid binding 4/2936 22/18639 0.181818181818182 1.15426058954669 0.464464216874304 0.950663140274064 GO:0034062 5'-3' RNA polymerase activity 4/2936 22/18639 0.181818181818182 1.15426058954669 0.464464216874304 0.950663140274064 GO:0097747 RNA polymerase activity 4/2936 22/18639 0.181818181818182 1.15426058954669 0.464464216874304 0.950663140274064 GO:0140035 ubiquitin-like protein reader activity 4/2936 22/18639 0.181818181818182 1.15426058954669 0.464464216874304 0.950663140274064 GO:0042379 chemokine receptor binding 12/2936 72/18639 0.166666666666667 1.05807220708447 0.464805122391518 0.950663140274064 GO:0001784 phosphotyrosine residue binding 8/2936 47/18639 0.170212765957447 1.08058438170329 0.466188138496837 0.950663140274064 GO:0061733 protein-lysine-acetyltransferase activity 8/2936 47/18639 0.170212765957447 1.08058438170329 0.466188138496837 0.950663140274064 GO:0046982 protein heterodimerization activity 59/2936 369/18639 0.159891598915989 1.01506114175583 0.47210554121215 0.950663140274064 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 3/2936 16/18639 0.1875 1.19033123297003 0.472743141662396 0.950663140274064 GO:0004708 MAP kinase kinase activity 3/2936 16/18639 0.1875 1.19033123297003 0.472743141662396 0.950663140274064 GO:0005149 interleukin-1 receptor binding 3/2936 16/18639 0.1875 1.19033123297003 0.472743141662396 0.950663140274064 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 3/2936 16/18639 0.1875 1.19033123297003 0.472743141662396 0.950663140274064 GO:0034450 ubiquitin-ubiquitin ligase activity 3/2936 16/18639 0.1875 1.19033123297003 0.472743141662396 0.950663140274064 GO:0097027 ubiquitin-protein transferase activator activity 3/2936 16/18639 0.1875 1.19033123297003 0.472743141662396 0.950663140274064 GO:0061650 ubiquitin-like protein conjugating enzyme activity 7/2936 41/18639 0.170731707317073 1.08387884628165 0.473058948210458 0.950663140274064 GO:0140318 protein transporter activity 7/2936 41/18639 0.170731707317073 1.08387884628165 0.473058948210458 0.950663140274064 GO:0140828 metal cation:monoatomic cation antiporter activity 7/2936 41/18639 0.170731707317073 1.08387884628165 0.473058948210458 0.950663140274064 GO:0008170 N-methyltransferase activity 16/2936 98/18639 0.163265306122449 1.03647889673581 0.480384985734819 0.950663140274064 GO:0010485 histone H4 acetyltransferase activity 6/2936 35/18639 0.171428571428571 1.0883028415726 0.480856787180357 0.950663140274064 GO:0061631 ubiquitin conjugating enzyme activity 6/2936 35/18639 0.171428571428571 1.0883028415726 0.480856787180357 0.950663140274064 GO:0016779 nucleotidyltransferase activity 22/2936 136/18639 0.161764705882353 1.02695243628787 0.482055233674959 0.950663140274064 GO:0004090 carbonyl reductase (NADPH) activity 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0004935 adrenergic receptor activity 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0008140 cAMP response element binding protein binding 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0008190 eukaryotic initiation factor 4E binding 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0008239 dipeptidyl-peptidase activity 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0008401 retinoic acid 4-hydroxylase activity 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0016427 tRNA (cytidine) methyltransferase activity 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0031956 medium-chain fatty acid-CoA ligase activity 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0032395 MHC class II receptor activity 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0035256 G protein-coupled glutamate receptor binding 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0043121 neurotrophin binding 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0043422 protein kinase B binding 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0045322 unmethylated CpG binding 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0051378 serotonin binding 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0051880 G-quadruplex DNA binding 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0098505 G-rich strand telomeric DNA binding 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0141109 transporter activator activity 2/2936 10/18639 0.2 1.26968664850136 0.483103233033683 0.950663140274064 GO:0017069 snRNA binding 9/2936 54/18639 0.166666666666667 1.05807220708447 0.483696241991012 0.950663140274064 GO:0008234 cysteine-type peptidase activity 30/2936 187/18639 0.160427807486631 1.01846522607061 0.487425709698436 0.956554658522306 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 5/2936 29/18639 0.172413793103448 1.09455745560462 0.489953566788937 0.958636694301109 GO:0097472 cyclin-dependent protein kinase activity 5/2936 29/18639 0.172413793103448 1.09455745560462 0.489953566788937 0.958636694301109 GO:0004402 histone acetyltransferase activity 7/2936 42/18639 0.166666666666667 1.05807220708447 0.499930865862321 0.971532680014655 GO:0042056 chemoattractant activity 7/2936 42/18639 0.166666666666667 1.05807220708447 0.499930865862321 0.971532680014655 GO:0140597 protein carrier chaperone 30/2936 188/18639 0.159574468085106 1.01304785784683 0.500094551014471 0.971532680014655 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 4/2936 23/18639 0.173913043478261 1.10407534652292 0.501004610810924 0.971532680014655 GO:0140103 catalytic activity, acting on a glycoprotein 4/2936 23/18639 0.173913043478261 1.10407534652292 0.501004610810924 0.971532680014655 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 4/2936 23/18639 0.173913043478261 1.10407534652292 0.501004610810924 0.971532680014655 GO:0035064 methylated histone binding 12/2936 74/18639 0.162162162162162 1.02947566094705 0.505322788638254 0.971905487271036 GO:0030145 manganese ion binding 11/2936 68/18639 0.161764705882353 1.02695243628787 0.512838321216958 0.971905487271036 GO:0004029 aldehyde dehydrogenase (NAD+) activity 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0004550 nucleoside diphosphate kinase activity 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0008484 sulfuric ester hydrolase activity 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0008569 minus-end-directed microtubule motor activity 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0015278 intracellularly gated calcium channel activity 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0015347 sodium-independent organic anion transmembrane transporter activity 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0016018 cyclosporin A binding 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0030169 low-density lipoprotein particle binding 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0030548 acetylcholine receptor regulator activity 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0031489 myosin V binding 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0036041 long-chain fatty acid binding 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0045236 CXCR chemokine receptor binding 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0048038 quinone binding 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0070403 NAD+ binding 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0070492 oligosaccharide binding 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:1990226 histone methyltransferase binding 3/2936 17/18639 0.176470588235294 1.12031174867767 0.515325556755033 0.971905487271036 GO:0016763 pentosyltransferase activity 8/2936 49/18639 0.163265306122449 1.03647889673581 0.516109316633823 0.971981090548137 GO:0008187 poly-pyrimidine tract binding 5/2936 30/18639 0.166666666666667 1.05807220708447 0.521701053122407 0.978283036486351 GO:0048019 receptor antagonist activity 5/2936 30/18639 0.166666666666667 1.05807220708447 0.521701053122407 0.978283036486351 GO:0098918 structural constituent of synapse 5/2936 30/18639 0.166666666666667 1.05807220708447 0.521701053122407 0.978283036486351 GO:0170055 lipid transmembrane transporter activity 9/2936 56/18639 0.160714285714286 1.02028391397431 0.530211972229819 0.98053832626888 GO:0008080 N-acetyltransferase activity 11/2936 69/18639 0.159420289855072 1.01206906764601 0.533610600791085 0.98053832626888 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 2/2936 11/18639 0.181818181818182 1.15426058954669 0.536172742725178 0.98053832626888 GO:0001851 complement component C3b binding 2/2936 11/18639 0.181818181818182 1.15426058954669 0.536172742725178 0.98053832626888 GO:0004016 adenylate cyclase activity 2/2936 11/18639 0.181818181818182 1.15426058954669 0.536172742725178 0.98053832626888 GO:0004143 ATP-dependent diacylglycerol kinase activity 2/2936 11/18639 0.181818181818182 1.15426058954669 0.536172742725178 0.98053832626888 GO:0004523 RNA-DNA hybrid ribonuclease activity 2/2936 11/18639 0.181818181818182 1.15426058954669 0.536172742725178 0.98053832626888 GO:0005114 type II transforming growth factor beta receptor binding 2/2936 11/18639 0.181818181818182 1.15426058954669 0.536172742725178 0.98053832626888 GO:0008046 axon guidance receptor activity 2/2936 11/18639 0.181818181818182 1.15426058954669 0.536172742725178 0.98053832626888 GO:0016594 glycine binding 2/2936 11/18639 0.181818181818182 1.15426058954669 0.536172742725178 0.98053832626888 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 2/2936 11/18639 0.181818181818182 1.15426058954669 0.536172742725178 0.98053832626888 GO:0019206 nucleoside kinase activity 2/2936 11/18639 0.181818181818182 1.15426058954669 0.536172742725178 0.98053832626888 GO:0034056 estrogen response element binding 2/2936 11/18639 0.181818181818182 1.15426058954669 0.536172742725178 0.98053832626888 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 2/2936 11/18639 0.181818181818182 1.15426058954669 0.536172742725178 0.98053832626888 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/2936 11/18639 0.181818181818182 1.15426058954669 0.536172742725178 0.98053832626888 GO:0140031 phosphorylation-dependent protein binding 2/2936 11/18639 0.181818181818182 1.15426058954669 0.536172742725178 0.98053832626888 GO:0180030 inositol phosphate kinase activity 2/2936 11/18639 0.181818181818182 1.15426058954669 0.536172742725178 0.98053832626888 GO:0005540 hyaluronic acid binding 4/2936 24/18639 0.166666666666667 1.05807220708447 0.53640773013179 0.98053832626888 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 42/2936 268/18639 0.156716417910448 0.994903717109277 0.540697751618083 0.986999946040272 GO:1901981 phosphatidylinositol phosphate binding 29/2936 185/18639 0.156756756756757 0.995159805582149 0.542795349621003 0.989447032014854 GO:0003697 single-stranded DNA binding 19/2936 121/18639 0.15702479338843 0.996861418244871 0.544623680992834 0.990709866054071 GO:0140034 methylation-dependent protein binding 12/2936 76/18639 0.157894736842105 1.00238419618529 0.545004126773433 0.990709866054071 GO:0047499 calcium-independent phospholipase A2 activity 5/2936 31/18639 0.161290322580645 1.02394084556561 0.552563110609239 0.992122360919087 GO:0070273 phosphatidylinositol-4-phosphate binding 5/2936 31/18639 0.161290322580645 1.02394084556561 0.552563110609239 0.992122360919087 GO:0070325 lipoprotein particle receptor binding 5/2936 31/18639 0.161290322580645 1.02394084556561 0.552563110609239 0.992122360919087 GO:0016278 lysine N-methyltransferase activity 11/2936 70/18639 0.157142857142857 0.997610938108213 0.554077163099226 0.992122360919087 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 3/2936 18/18639 0.166666666666667 1.05807220708447 0.555984575394644 0.992122360919087 GO:0008525 phosphatidylcholine transporter activity 3/2936 18/18639 0.166666666666667 1.05807220708447 0.555984575394644 0.992122360919087 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 3/2936 18/18639 0.166666666666667 1.05807220708447 0.555984575394644 0.992122360919087 GO:0016854 racemase and epimerase activity 3/2936 18/18639 0.166666666666667 1.05807220708447 0.555984575394644 0.992122360919087 GO:0017075 syntaxin-1 binding 3/2936 18/18639 0.166666666666667 1.05807220708447 0.555984575394644 0.992122360919087 GO:0030228 lipoprotein particle receptor activity 3/2936 18/18639 0.166666666666667 1.05807220708447 0.555984575394644 0.992122360919087 GO:0034185 apolipoprotein binding 3/2936 18/18639 0.166666666666667 1.05807220708447 0.555984575394644 0.992122360919087 GO:0070628 proteasome binding 3/2936 18/18639 0.166666666666667 1.05807220708447 0.555984575394644 0.992122360919087 GO:0099602 neurotransmitter receptor regulator activity 3/2936 18/18639 0.166666666666667 1.05807220708447 0.555984575394644 0.992122360919087 GO:0016407 acetyltransferase activity 15/2936 96/18639 0.15625 0.991942694141689 0.556967176868532 0.992122360919087 GO:0005506 iron ion binding 24/2936 154/18639 0.155844155844156 0.989366219611451 0.557167416155019 0.992122360919087 GO:0031267 small GTPase binding 44/2936 283/18639 0.15547703180212 0.987035557138868 0.56334262994512 1 GO:0042162 telomeric DNA binding 6/2936 38/18639 0.157894736842105 1.00238419618529 0.565913105275969 1 GO:0008139 nuclear localization sequence binding 4/2936 25/18639 0.16 1.01574931880109 0.570495577585633 1 GO:0015662 P-type ion transporter activity 4/2936 25/18639 0.16 1.01574931880109 0.570495577585633 1 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 4/2936 25/18639 0.16 1.01574931880109 0.570495577585633 1 GO:0047617 fatty acyl-CoA hydrolase activity 4/2936 25/18639 0.16 1.01574931880109 0.570495577585633 1 GO:0140358 P-type transmembrane transporter activity 4/2936 25/18639 0.16 1.01574931880109 0.570495577585633 1 GO:0030695 GTPase regulator activity 76/2936 489/18639 0.155419222903885 0.986668561207603 0.570984457932136 1 GO:0004527 exonuclease activity 13/2936 84/18639 0.154761904761905 0.98249562086415 0.573966506916928 1 GO:0008009 chemokine activity 7/2936 45/18639 0.155555555555556 0.987534059945504 0.577432843283133 1 GO:0008083 growth factor activity 25/2936 162/18639 0.154320987654321 0.979696488041175 0.578108274239416 1 GO:0060589 nucleoside-triphosphatase regulator activity 76/2936 490/18639 0.155102040816327 0.984654951899016 0.57871321791549 1 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 54/2936 349/18639 0.154727793696275 0.982279069041169 0.580435928043677 1 GO:0047498 calcium-dependent phospholipase A2 activity 5/2936 32/18639 0.15625 0.991942694141689 0.58241597901282 1 GO:0070717 poly-purine tract binding 5/2936 32/18639 0.15625 0.991942694141689 0.58241597901282 1 GO:0071813 lipoprotein particle binding 5/2936 32/18639 0.15625 0.991942694141689 0.58241597901282 1 GO:0071814 protein-lipid complex binding 5/2936 32/18639 0.15625 0.991942694141689 0.58241597901282 1 GO:0160215 deacylase activity 10/2936 65/18639 0.153846153846154 0.97668203730874 0.584943674029914 1 GO:0003995 acyl-CoA dehydrogenase activity 2/2936 12/18639 0.166666666666667 1.05807220708447 0.585354628789605 1 GO:0004000 adenosine deaminase activity 2/2936 12/18639 0.166666666666667 1.05807220708447 0.585354628789605 1 GO:0004875 complement receptor activity 2/2936 12/18639 0.166666666666667 1.05807220708447 0.585354628789605 1 GO:0005078 MAP-kinase scaffold activity 2/2936 12/18639 0.166666666666667 1.05807220708447 0.585354628789605 1 GO:0005095 GTPase inhibitor activity 2/2936 12/18639 0.166666666666667 1.05807220708447 0.585354628789605 1 GO:0008179 adenylate cyclase binding 2/2936 12/18639 0.166666666666667 1.05807220708447 0.585354628789605 1 GO:0008603 cAMP-dependent protein kinase regulator activity 2/2936 12/18639 0.166666666666667 1.05807220708447 0.585354628789605 1 GO:0010853 cyclase activator activity 2/2936 12/18639 0.166666666666667 1.05807220708447 0.585354628789605 1 GO:0015368 calcium:monoatomic cation antiporter activity 2/2936 12/18639 0.166666666666667 1.05807220708447 0.585354628789605 1 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/2936 12/18639 0.166666666666667 1.05807220708447 0.585354628789605 1 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 2/2936 12/18639 0.166666666666667 1.05807220708447 0.585354628789605 1 GO:0070679 inositol 1,4,5 trisphosphate binding 2/2936 12/18639 0.166666666666667 1.05807220708447 0.585354628789605 1 GO:1990459 transferrin receptor binding 2/2936 12/18639 0.166666666666667 1.05807220708447 0.585354628789605 1 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 3/2936 19/18639 0.157894736842105 1.00238419618529 0.594521228634025 1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 3/2936 19/18639 0.157894736842105 1.00238419618529 0.594521228634025 1 GO:0030506 ankyrin binding 3/2936 19/18639 0.157894736842105 1.00238419618529 0.594521228634025 1 GO:0042834 peptidoglycan binding 3/2936 19/18639 0.157894736842105 1.00238419618529 0.594521228634025 1 GO:0140036 ubiquitin-modified protein reader activity 3/2936 19/18639 0.157894736842105 1.00238419618529 0.594521228634025 1 GO:1990380 K48-linked deubiquitinase activity 3/2936 19/18639 0.157894736842105 1.00238419618529 0.594521228634025 1 GO:0030276 clathrin binding 7/2936 46/18639 0.152173913043478 0.966065928207558 0.601956524242496 1 GO:0004529 DNA exonuclease activity 4/2936 26/18639 0.153846153846154 0.97668203730874 0.603130204001428 1 GO:0008143 poly(A) binding 4/2936 26/18639 0.153846153846154 0.97668203730874 0.603130204001428 1 GO:0016289 acyl-CoA hydrolase activity 4/2936 26/18639 0.153846153846154 0.97668203730874 0.603130204001428 1 GO:0050681 nuclear androgen receptor binding 4/2936 26/18639 0.153846153846154 0.97668203730874 0.603130204001428 1 GO:0070006 metalloaminopeptidase activity 4/2936 26/18639 0.153846153846154 0.97668203730874 0.603130204001428 1 GO:0070412 R-SMAD binding 4/2936 26/18639 0.153846153846154 0.97668203730874 0.603130204001428 1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 13/2936 86/18639 0.151162790697674 0.959646885495216 0.609985853682615 1 GO:0016251 RNA polymerase II general transcription initiation factor activity 8/2936 53/18639 0.150943396226415 0.958254074340651 0.610343962403599 1 GO:0140416 transcription regulator inhibitor activity 5/2936 33/18639 0.151515151515152 0.961883824622244 0.611159297738924 1 GO:0005085 guanyl-nucleotide exchange factor activity 35/2936 230/18639 0.152173913043478 0.966065928207558 0.616547381829729 1 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 9/2936 60/18639 0.15 0.952264986376022 0.618081080606794 1 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 6/2936 40/18639 0.15 0.952264986376022 0.618665685554394 1 GO:0043130 ubiquitin binding 15/2936 100/18639 0.15 0.952264986376022 0.624145801384511 1 GO:0043495 protein-membrane adaptor activity 7/2936 47/18639 0.148936170212766 0.945511333990376 0.625715991747986 1 GO:0004993 G protein-coupled serotonin receptor activity 2/2936 13/18639 0.153846153846154 0.97668203730874 0.630556540267609 1 GO:0005172 vascular endothelial growth factor receptor binding 2/2936 13/18639 0.153846153846154 0.97668203730874 0.630556540267609 1 GO:0008035 high-density lipoprotein particle binding 2/2936 13/18639 0.153846153846154 0.97668203730874 0.630556540267609 1 GO:0008253 5'-nucleotidase activity 2/2936 13/18639 0.153846153846154 0.97668203730874 0.630556540267609 1 GO:0009982 pseudouridine synthase activity 2/2936 13/18639 0.153846153846154 0.97668203730874 0.630556540267609 1 GO:0032396 inhibitory MHC class I receptor activity 2/2936 13/18639 0.153846153846154 0.97668203730874 0.630556540267609 1 GO:0061459 L-arginine transmembrane transporter activity 2/2936 13/18639 0.153846153846154 0.97668203730874 0.630556540267609 1 GO:0140333 glycerophospholipid flippase activity 2/2936 13/18639 0.153846153846154 0.97668203730874 0.630556540267609 1 GO:0000339 RNA cap binding 3/2936 20/18639 0.15 0.952264986376022 0.630807211789257 1 GO:0001614 purinergic nucleotide receptor activity 3/2936 20/18639 0.15 0.952264986376022 0.630807211789257 1 GO:0010851 cyclase regulator activity 3/2936 20/18639 0.15 0.952264986376022 0.630807211789257 1 GO:0016408 C-acyltransferase activity 3/2936 20/18639 0.15 0.952264986376022 0.630807211789257 1 GO:0016502 nucleotide receptor activity 3/2936 20/18639 0.15 0.952264986376022 0.630807211789257 1 GO:0052745 inositol phosphate phosphatase activity 3/2936 20/18639 0.15 0.952264986376022 0.630807211789257 1 GO:0061608 nuclear import signal receptor activity 3/2936 20/18639 0.15 0.952264986376022 0.630807211789257 1 GO:0005044 scavenger receptor activity 4/2936 27/18639 0.148148148148148 0.940508628519528 0.634210241556943 1 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 4/2936 27/18639 0.148148148148148 0.940508628519528 0.634210241556943 1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 9/2936 61/18639 0.147540983606557 0.936654084960021 0.638676494474169 1 GO:0019825 oxygen binding 5/2936 34/18639 0.147058823529412 0.933593123898061 0.638714739984186 1 GO:0001727 lipid kinase activity 6/2936 41/18639 0.146341463414634 0.929039011098558 0.643626840527641 1 GO:0008227 G protein-coupled amine receptor activity 6/2936 41/18639 0.146341463414634 0.929039011098558 0.643626840527641 1 GO:0042287 MHC protein binding 6/2936 41/18639 0.146341463414634 0.929039011098558 0.643626840527641 1 GO:1990841 promoter-specific chromatin binding 10/2936 68/18639 0.147058823529412 0.933593123898061 0.644677693729298 1 GO:0032266 phosphatidylinositol-3-phosphate binding 7/2936 48/18639 0.145833333333333 0.92581318119891 0.648661598248434 1 GO:0008276 protein methyltransferase activity 14/2936 95/18639 0.147368421052632 0.935558583106267 0.650294920387736 1 GO:0008238 exopeptidase activity 15/2936 102/18639 0.147058823529412 0.933593123898061 0.655822115935163 1 GO:0005125 cytokine activity 35/2936 234/18639 0.14957264957265 0.949551980716831 0.658854274293732 1 GO:0016279 protein-lysine N-methyltransferase activity 10/2936 69/18639 0.144927536231884 0.920062788769103 0.663502624735774 1 GO:0036408 histone H3K14 acetyltransferase activity 4/2936 28/18639 0.142857142857143 0.90691903464383 0.663667143688862 1 GO:0045499 chemorepellent activity 4/2936 28/18639 0.142857142857143 0.90691903464383 0.663667143688862 1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 4/2936 28/18639 0.142857142857143 0.90691903464383 0.663667143688862 1 GO:0015174 basic amino acid transmembrane transporter activity 3/2936 21/18639 0.142857142857143 0.90691903464383 0.66477382485315 1 GO:0035613 RNA stem-loop binding 3/2936 21/18639 0.142857142857143 0.90691903464383 0.66477382485315 1 GO:0036122 BMP binding 3/2936 21/18639 0.142857142857143 0.90691903464383 0.66477382485315 1 GO:0051428 peptide hormone receptor binding 3/2936 21/18639 0.142857142857143 0.90691903464383 0.66477382485315 1 GO:0004623 phospholipase A2 activity 5/2936 35/18639 0.142857142857143 0.90691903464383 0.665024398784823 1 GO:0043015 gamma-tubulin binding 5/2936 35/18639 0.142857142857143 0.90691903464383 0.665024398784823 1 GO:0140566 histone reader activity 5/2936 35/18639 0.142857142857143 0.90691903464383 0.665024398784823 1 GO:0035198 miRNA binding 6/2936 42/18639 0.142857142857143 0.90691903464383 0.667576169638527 1 GO:0048487 beta-tubulin binding 6/2936 42/18639 0.142857142857143 0.90691903464383 0.667576169638527 1 GO:0004065 arylsulfatase activity 2/2936 14/18639 0.142857142857143 0.90691903464383 0.671811636789796 1 GO:0005313 L-glutamate transmembrane transporter activity 2/2936 14/18639 0.142857142857143 0.90691903464383 0.671811636789796 1 GO:0005344 oxygen carrier activity 2/2936 14/18639 0.142857142857143 0.90691903464383 0.671811636789796 1 GO:0005347 ATP transmembrane transporter activity 2/2936 14/18639 0.142857142857143 0.90691903464383 0.671811636789796 1 GO:0015386 potassium:proton antiporter activity 2/2936 14/18639 0.142857142857143 0.90691903464383 0.671811636789796 1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/2936 14/18639 0.142857142857143 0.90691903464383 0.671811636789796 1 GO:0043176 amine binding 2/2936 14/18639 0.142857142857143 0.90691903464383 0.671811636789796 1 GO:0030170 pyridoxal phosphate binding 8/2936 56/18639 0.142857142857143 0.90691903464383 0.674268362613198 1 GO:0016922 nuclear receptor binding 20/2936 137/18639 0.145985401459854 0.92677857554844 0.680447377805192 1 GO:0008168 methyltransferase activity 30/2936 204/18639 0.147058823529412 0.933593123898061 0.688879312915694 1 GO:1902936 phosphatidylinositol bisphosphate binding 16/2936 111/18639 0.144144144144144 0.915089476397378 0.690185083732413 1 GO:0010484 histone H3 acetyltransferase activity 4/2936 29/18639 0.137931034482759 0.875645964483698 0.69146131599285 1 GO:0016417 S-acyltransferase activity 4/2936 29/18639 0.137931034482759 0.875645964483698 0.69146131599285 1 GO:0099604 ligand-gated calcium channel activity 4/2936 29/18639 0.137931034482759 0.875645964483698 0.69146131599285 1 GO:0048020 CCR chemokine receptor binding 7/2936 50/18639 0.14 0.888780653950954 0.69196183889424 1 GO:0070279 vitamin B6 binding 8/2936 57/18639 0.140350877192982 0.891008174386921 0.694081975814219 1 GO:0005243 gap junction channel activity 3/2936 22/18639 0.136363636363636 0.86569544216002 0.696401657691915 1 GO:0008093 cytoskeletal anchor activity 3/2936 22/18639 0.136363636363636 0.86569544216002 0.696401657691915 1 GO:0008649 rRNA methyltransferase activity 3/2936 22/18639 0.136363636363636 0.86569544216002 0.696401657691915 1 GO:0015377 chloride:monoatomic cation symporter activity 3/2936 22/18639 0.136363636363636 0.86569544216002 0.696401657691915 1 GO:0031683 G-protein beta/gamma-subunit complex binding 3/2936 22/18639 0.136363636363636 0.86569544216002 0.696401657691915 1 GO:0030527 structural constituent of chromatin 14/2936 98/18639 0.142857142857143 0.90691903464383 0.696857493797956 1 GO:0035091 phosphatidylinositol binding 42/2936 284/18639 0.147887323943662 0.938852803469317 0.697703944738326 1 GO:0046906 tetrapyrrole binding 22/2936 152/18639 0.144736842105263 0.918852179836512 0.701273467723261 1 GO:0004089 carbonate dehydratase activity 2/2936 15/18639 0.133333333333333 0.846457765667575 0.709241361408958 1 GO:0004953 icosanoid receptor activity 2/2936 15/18639 0.133333333333333 0.846457765667575 0.709241361408958 1 GO:0015556 C4-dicarboxylate transmembrane transporter activity 2/2936 15/18639 0.133333333333333 0.846457765667575 0.709241361408958 1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 2/2936 15/18639 0.133333333333333 0.846457765667575 0.709241361408958 1 GO:0033130 acetylcholine receptor binding 2/2936 15/18639 0.133333333333333 0.846457765667575 0.709241361408958 1 GO:0051371 muscle alpha-actinin binding 2/2936 15/18639 0.133333333333333 0.846457765667575 0.709241361408958 1 GO:0005048 signal sequence binding 7/2936 51/18639 0.137254901960784 0.871353582304857 0.712264676441077 1 GO:0140030 modification-dependent protein binding 25/2936 173/18639 0.144508670520231 0.9174036477611 0.712509006636879 1 GO:0019213 deacetylase activity 5/2936 37/18639 0.135135135135135 0.857896384122542 0.713766097753122 1 GO:0001965 G-protein alpha-subunit binding 4/2936 30/18639 0.133333333333333 0.846457765667575 0.717578279511379 1 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 4/2936 30/18639 0.133333333333333 0.846457765667575 0.717578279511379 1 GO:0015215 nucleotide transmembrane transporter activity 4/2936 30/18639 0.133333333333333 0.846457765667575 0.717578279511379 1 GO:0043995 histone H4K5 acetyltransferase activity 4/2936 30/18639 0.133333333333333 0.846457765667575 0.717578279511379 1 GO:0043996 histone H4K8 acetyltransferase activity 4/2936 30/18639 0.133333333333333 0.846457765667575 0.717578279511379 1 GO:0043997 histone H4K12 acetyltransferase activity 4/2936 30/18639 0.133333333333333 0.846457765667575 0.717578279511379 1 GO:0051721 protein phosphatase 2A binding 4/2936 30/18639 0.133333333333333 0.846457765667575 0.717578279511379 1 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 24/2936 167/18639 0.143712574850299 0.912349687545889 0.720035883717376 1 GO:0032182 ubiquitin-like protein binding 17/2936 120/18639 0.141666666666667 0.899361376021798 0.720853733075395 1 GO:0051213 dioxygenase activity 13/2936 93/18639 0.139784946236559 0.887415399490199 0.723224786438366 1 GO:0019783 ubiquitin-like protein peptidase activity 18/2936 127/18639 0.141732283464567 0.899777939882855 0.723924104060493 1 GO:0008171 O-methyltransferase activity 3/2936 23/18639 0.130434782608696 0.828056509892193 0.725711214724063 1 GO:0017134 fibroblast growth factor binding 3/2936 23/18639 0.130434782608696 0.828056509892193 0.725711214724063 1 GO:0044013 histone H2B acetyltransferase activity 3/2936 23/18639 0.130434782608696 0.828056509892193 0.725711214724063 1 GO:0070577 lysine-acetylated histone binding 3/2936 23/18639 0.130434782608696 0.828056509892193 0.725711214724063 1 GO:0099186 structural constituent of postsynapse 3/2936 23/18639 0.130434782608696 0.828056509892193 0.725711214724063 1 GO:0140102 catalytic activity, acting on a rRNA 3/2936 23/18639 0.130434782608696 0.828056509892193 0.725711214724063 1 GO:0000146 microfilament motor activity 5/2936 38/18639 0.131578947368421 0.835320163487738 0.736168066310266 1 GO:0005164 tumor necrosis factor receptor binding 4/2936 31/18639 0.129032258064516 0.819152676452492 0.742024971200585 1 GO:0005310 dicarboxylic acid transmembrane transporter activity 4/2936 31/18639 0.129032258064516 0.819152676452492 0.742024971200585 1 GO:0015378 sodium:chloride symporter activity 2/2936 16/18639 0.125 0.793554155313351 0.743026821372753 1 GO:0015385 sodium:proton antiporter activity 2/2936 16/18639 0.125 0.793554155313351 0.743026821372753 1 GO:0015923 mannosidase activity 2/2936 16/18639 0.125 0.793554155313351 0.743026821372753 1 GO:0016722 oxidoreductase activity, acting on metal ions 2/2936 16/18639 0.125 0.793554155313351 0.743026821372753 1 GO:0017070 U6 snRNA binding 2/2936 16/18639 0.125 0.793554155313351 0.743026821372753 1 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/2936 16/18639 0.125 0.793554155313351 0.743026821372753 1 GO:0140327 flippase activity 2/2936 16/18639 0.125 0.793554155313351 0.743026821372753 1 GO:0140328 floppase activity 2/2936 16/18639 0.125 0.793554155313351 0.743026821372753 1 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 8/2936 60/18639 0.133333333333333 0.846457765667575 0.748764890115662 1 GO:0017046 peptide hormone binding 7/2936 53/18639 0.132075471698113 0.838472315048069 0.750108210868773 1 GO:0004180 carboxypeptidase activity 6/2936 46/18639 0.130434782608696 0.828056509892193 0.752727779986381 1 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 6/2936 46/18639 0.130434782608696 0.828056509892193 0.752727779986381 1 GO:0004622 lysophospholipase activity 3/2936 24/18639 0.125 0.793554155313351 0.752754569665817 1 GO:0004806 triacylglycerol lipase activity 3/2936 24/18639 0.125 0.793554155313351 0.752754569665817 1 GO:0005315 phosphate transmembrane transporter activity 3/2936 24/18639 0.125 0.793554155313351 0.752754569665817 1 GO:0030215 semaphorin receptor binding 3/2936 24/18639 0.125 0.793554155313351 0.752754569665817 1 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/2936 24/18639 0.125 0.793554155313351 0.752754569665817 1 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/2936 24/18639 0.125 0.793554155313351 0.752754569665817 1 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/2936 24/18639 0.125 0.793554155313351 0.752754569665817 1 GO:0050699 WW domain binding 3/2936 24/18639 0.125 0.793554155313351 0.752754569665817 1 GO:0140033 acetylation-dependent protein binding 3/2936 24/18639 0.125 0.793554155313351 0.752754569665817 1 GO:0005096 GTPase activator activity 39/2936 271/18639 0.143911439114391 0.913612164050796 0.756131005514342 1 GO:0003777 microtubule motor activity 9/2936 68/18639 0.132352941176471 0.840233811508254 0.764116639312243 1 GO:0140223 general transcription initiation factor activity 9/2936 68/18639 0.132352941176471 0.840233811508254 0.764116639312243 1 GO:0015026 coreceptor activity 8/2936 61/18639 0.131147540983607 0.832581408853352 0.765382006438906 1 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 7/2936 54/18639 0.12962962962963 0.822945049954587 0.767643740777507 1 GO:0016791 phosphatase activity 39/2936 273/18639 0.142857142857143 0.90691903464383 0.772031460028695 1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/2936 17/18639 0.117647058823529 0.746874499118448 0.773386989988449 1 GO:0008429 phosphatidylethanolamine binding 2/2936 17/18639 0.117647058823529 0.746874499118448 0.773386989988449 1 GO:0016805 dipeptidase activity 2/2936 17/18639 0.117647058823529 0.746874499118448 0.773386989988449 1 GO:0032183 SUMO binding 2/2936 17/18639 0.117647058823529 0.746874499118448 0.773386989988449 1 GO:0046965 nuclear retinoid X receptor binding 2/2936 17/18639 0.117647058823529 0.746874499118448 0.773386989988449 1 GO:0008194 UDP-glycosyltransferase activity 20/2936 145/18639 0.137931034482759 0.875645964483698 0.774468616380429 1 GO:0004177 aminopeptidase activity 5/2936 40/18639 0.125 0.793554155313351 0.77705958570704 1 GO:0032451 demethylase activity 5/2936 40/18639 0.125 0.793554155313351 0.77705958570704 1 GO:0071855 neuropeptide receptor binding 5/2936 40/18639 0.125 0.793554155313351 0.77705958570704 1 GO:0004709 MAP kinase kinase kinase activity 3/2936 25/18639 0.12 0.761811989100817 0.777608068585842 1 GO:0015296 monoatomic anion:monoatomic cation symporter activity 3/2936 25/18639 0.12 0.761811989100817 0.777608068585842 1 GO:0019706 protein-cysteine S-palmitoyltransferase activity 3/2936 25/18639 0.12 0.761811989100817 0.777608068585842 1 GO:0019707 protein-cysteine S-acyltransferase activity 3/2936 25/18639 0.12 0.761811989100817 0.777608068585842 1 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 3/2936 25/18639 0.12 0.761811989100817 0.777608068585842 1 GO:0120020 cholesterol transfer activity 3/2936 25/18639 0.12 0.761811989100817 0.777608068585842 1 GO:0019956 chemokine binding 4/2936 33/18639 0.121212121212121 0.769507059697795 0.78602169828986 1 GO:0003774 cytoskeletal motor activity 21/2936 153/18639 0.137254901960784 0.871353582304857 0.786234422952035 1 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 12/2936 91/18639 0.131868131868132 0.83715603197892 0.790106258332101 1 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 25/2936 181/18639 0.138121546961326 0.876855420235747 0.792476442848465 1 GO:0016741 transferase activity, transferring one-carbon groups 30/2936 215/18639 0.13953488372093 0.885827894303276 0.79260896112431 1 GO:0008028 monocarboxylic acid transmembrane transporter activity 9/2936 70/18639 0.128571428571429 0.816227131179447 0.793589345734969 1 GO:0015085 calcium ion transmembrane transporter activity 20/2936 147/18639 0.136054421768707 0.863732413946505 0.794769018429259 1 GO:0015175 neutral L-amino acid transmembrane transporter activity 5/2936 41/18639 0.121951219512195 0.774199175915465 0.795591911426402 1 GO:0008157 protein phosphatase 1 binding 3/2936 26/18639 0.115384615384615 0.732511527981555 0.800366050922939 1 GO:0019865 immunoglobulin binding 3/2936 26/18639 0.115384615384615 0.732511527981555 0.800366050922939 1 GO:0052742 phosphatidylinositol kinase activity 3/2936 26/18639 0.115384615384615 0.732511527981555 0.800366050922939 1 GO:0003746 translation elongation factor activity 2/2936 18/18639 0.111111111111111 0.705381471389646 0.800562291812675 1 GO:0004706 JUN kinase kinase kinase activity 2/2936 18/18639 0.111111111111111 0.705381471389646 0.800562291812675 1 GO:0015172 acidic amino acid transmembrane transporter activity 2/2936 18/18639 0.111111111111111 0.705381471389646 0.800562291812675 1 GO:0015373 monoatomic anion:sodium symporter activity 2/2936 18/18639 0.111111111111111 0.705381471389646 0.800562291812675 1 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/2936 18/18639 0.111111111111111 0.705381471389646 0.800562291812675 1 GO:0043175 RNA polymerase core enzyme binding 5/2936 42/18639 0.119047619047619 0.755765862203192 0.812891335992331 1 GO:0020037 heme binding 19/2936 142/18639 0.133802816901408 0.849438250757954 0.813150472519559 1 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0003796 lysozyme activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0004955 prostaglandin receptor activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0008519 ammonium channel activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0015187 glycine transmembrane transporter activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0015203 polyamine transmembrane transporter activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0016783 sulfurtransferase activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0019531 oxalate transmembrane transporter activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0031434 mitogen-activated protein kinase kinase binding 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0031720 haptoglobin binding 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0035374 chondroitin sulfate binding 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0042166 acetylcholine binding 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0042975 peroxisome proliferator activated receptor binding 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0043208 glycosphingolipid binding 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0043295 glutathione binding 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0051864 histone H3K36 demethylase activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0070513 death domain binding 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0140135 mechanosensitive monoatomic cation channel activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0140940 histone H2A methyltransferase activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0140999 histone H3K4 trimethyltransferase activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:1905394 retromer complex binding 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:1990259 histone H2AQ104 methyltransferase activity 1/2936 10/18639 0.1 0.634843324250681 0.819945446336188 1 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/2936 27/18639 0.111111111111111 0.705381471389646 0.821135527093689 1 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 16/2936 122/18639 0.131147540983607 0.832581408853352 0.822142816608999 1 GO:0005229 intracellularly calcium-gated chloride channel activity 2/2936 19/18639 0.105263157894737 0.668256130790191 0.824802416892516 1 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/2936 19/18639 0.105263157894737 0.668256130790191 0.824802416892516 1 GO:0008381 mechanosensitive monoatomic ion channel activity 2/2936 19/18639 0.105263157894737 0.668256130790191 0.824802416892516 1 GO:0008574 plus-end-directed microtubule motor activity 2/2936 19/18639 0.105263157894737 0.668256130790191 0.824802416892516 1 GO:0022821 solute:potassium antiporter activity 2/2936 19/18639 0.105263157894737 0.668256130790191 0.824802416892516 1 GO:0022840 leak channel activity 2/2936 19/18639 0.105263157894737 0.668256130790191 0.824802416892516 1 GO:0022842 narrow pore channel activity 2/2936 19/18639 0.105263157894737 0.668256130790191 0.824802416892516 1 GO:0042800 histone H3K4 methyltransferase activity 2/2936 19/18639 0.105263157894737 0.668256130790191 0.824802416892516 1 GO:0099589 serotonin receptor activity 2/2936 19/18639 0.105263157894737 0.668256130790191 0.824802416892516 1 GO:0141147 intracellularly calcium-gated channel activity 2/2936 19/18639 0.105263157894737 0.668256130790191 0.824802416892516 1 GO:0008081 phosphoric diester hydrolase activity 11/2936 87/18639 0.126436781609195 0.80267546744339 0.827068140265834 1 GO:0061980 regulatory RNA binding 7/2936 58/18639 0.120689655172414 0.766190218923236 0.828758154117028 1 GO:0042578 phosphoric ester hydrolase activity 51/2936 363/18639 0.140495867768595 0.89192863737699 0.834301606169354 1 GO:0005272 sodium channel activity 6/2936 51/18639 0.117647058823529 0.746874499118448 0.835237970263166 1 GO:0008235 metalloexopeptidase activity 8/2936 66/18639 0.121212121212121 0.769507059697795 0.836605222523498 1 GO:0046966 nuclear thyroid hormone receptor binding 3/2936 28/18639 0.107142857142857 0.680189275982873 0.840031733102268 1 GO:0051393 alpha-actinin binding 3/2936 28/18639 0.107142857142857 0.680189275982873 0.840031733102268 1 GO:0141052 histone H3 demethylase activity 3/2936 28/18639 0.107142857142857 0.680189275982873 0.840031733102268 1 GO:0005262 calcium channel activity 17/2936 131/18639 0.129770992366412 0.823842481852029 0.840373380746309 1 GO:0005484 SNAP receptor activity 4/2936 36/18639 0.111111111111111 0.705381471389646 0.840529554394654 1 GO:0016409 palmitoyltransferase activity 4/2936 36/18639 0.111111111111111 0.705381471389646 0.840529554394654 1 GO:0015101 organic cation transmembrane transporter activity 10/2936 81/18639 0.123456790123457 0.78375719043294 0.840753167092042 1 GO:0031593 polyubiquitin modification-dependent protein binding 7/2936 59/18639 0.11864406779661 0.753203944026232 0.84187208495455 1 GO:0004222 metalloendopeptidase activity 14/2936 110/18639 0.127272727272727 0.807982412682685 0.842841336853122 1 GO:0016790 thiolester hydrolase activity 5/2936 44/18639 0.113636363636364 0.721412868466683 0.843958110828338 1 GO:0015095 magnesium ion transmembrane transporter activity 2/2936 20/18639 0.1 0.634843324250681 0.846357439681767 1 GO:0042288 MHC class I protein binding 2/2936 20/18639 0.1 0.634843324250681 0.846357439681767 1 GO:0015079 potassium ion transmembrane transporter activity 21/2936 160/18639 0.13125 0.833231863079019 0.84786079773049 1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/2936 11/18639 0.0909090909090909 0.577130294773347 0.848322716697289 1 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/2936 11/18639 0.0909090909090909 0.577130294773347 0.848322716697289 1 GO:0004954 prostanoid receptor activity 1/2936 11/18639 0.0909090909090909 0.577130294773347 0.848322716697289 1 GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity 1/2936 11/18639 0.0909090909090909 0.577130294773347 0.848322716697289 1 GO:0008271 secondary active sulfate transmembrane transporter activity 1/2936 11/18639 0.0909090909090909 0.577130294773347 0.848322716697289 1 GO:0015217 ADP transmembrane transporter activity 1/2936 11/18639 0.0909090909090909 0.577130294773347 0.848322716697289 1 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/2936 11/18639 0.0909090909090909 0.577130294773347 0.848322716697289 1 GO:0019864 IgG binding 1/2936 11/18639 0.0909090909090909 0.577130294773347 0.848322716697289 1 GO:0032050 clathrin heavy chain binding 1/2936 11/18639 0.0909090909090909 0.577130294773347 0.848322716697289 1 GO:0034511 U3 snoRNA binding 1/2936 11/18639 0.0909090909090909 0.577130294773347 0.848322716697289 1 GO:0043522 leucine zipper domain binding 1/2936 11/18639 0.0909090909090909 0.577130294773347 0.848322716697289 1 GO:0043855 cyclic nucleotide-activated monoatomic ion channel activity 1/2936 11/18639 0.0909090909090909 0.577130294773347 0.848322716697289 1 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/2936 11/18639 0.0909090909090909 0.577130294773347 0.848322716697289 1 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/2936 11/18639 0.0909090909090909 0.577130294773347 0.848322716697289 1 GO:1900750 oligopeptide binding 1/2936 11/18639 0.0909090909090909 0.577130294773347 0.848322716697289 1 GO:0140767 enzyme-substrate adaptor activity 18/2936 139/18639 0.129496402877698 0.822099268813832 0.848448724678848 1 GO:0042054 histone methyltransferase activity 8/2936 67/18639 0.119402985074627 0.758021879702306 0.848577653567589 1 GO:0030159 signaling receptor complex adaptor activity 6/2936 52/18639 0.115384615384615 0.732511527981555 0.848749603537552 1 GO:0042805 actinin binding 4/2936 37/18639 0.108108108108108 0.686317107298034 0.855894821866355 1 GO:0004181 metallocarboxypeptidase activity 3/2936 29/18639 0.103448275862069 0.656734473362774 0.85717447353797 1 GO:0051861 glycolipid binding 3/2936 29/18639 0.103448275862069 0.656734473362774 0.85717447353797 1 GO:0106222 lncRNA binding 3/2936 29/18639 0.103448275862069 0.656734473362774 0.85717447353797 1 GO:0046915 transition metal ion transmembrane transporter activity 5/2936 45/18639 0.111111111111111 0.705381471389646 0.857820129179407 1 GO:0141003 histone H2AX kinase activity 49/2936 354/18639 0.138418079096045 0.878737934697271 0.858272817402759 1 GO:0042626 ATPase-coupled transmembrane transporter activity 12/2936 98/18639 0.122448979591837 0.777359172551854 0.865028662024089 1 GO:0008373 sialyltransferase activity 2/2936 21/18639 0.0952380952380952 0.604612689762554 0.865471504400569 1 GO:1904047 S-adenosyl-L-methionine binding 2/2936 21/18639 0.0952380952380952 0.604612689762554 0.865471504400569 1 GO:0008237 metallopeptidase activity 24/2936 184/18639 0.130434782608696 0.828056509892193 0.869102490767033 1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 5/2936 46/18639 0.108695652173913 0.690047091576827 0.870636269324897 1 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0003720 telomerase activity 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0004032 aldose reductase (NADPH) activity 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0005247 voltage-gated chloride channel activity 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0005436 sodium:phosphate symporter activity 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0008504 monoamine transmembrane transporter activity 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0015132 prostaglandin transmembrane transporter activity 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0016208 AMP binding 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0016273 arginine N-methyltransferase activity 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0016274 protein-arginine N-methyltransferase activity 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0017166 vinculin binding 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0034452 dynactin binding 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0035197 siRNA binding 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0035251 UDP-glucosyltransferase activity 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0036009 protein-glutamine N-methyltransferase activity 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0070008 serine-type exopeptidase activity 1/2936 12/18639 0.0833333333333333 0.529036103542234 0.872228906507079 1 GO:0008106 alcohol dehydrogenase (NADP+) activity 3/2936 30/18639 0.1 0.634843324250681 0.872685161763146 1 GO:0031210 phosphatidylcholine binding 3/2936 30/18639 0.1 0.634843324250681 0.872685161763146 1 GO:0032452 histone demethylase activity 3/2936 30/18639 0.1 0.634843324250681 0.872685161763146 1 GO:0140996 histone H3 kinase activity 49/2936 357/18639 0.137254901960784 0.871353582304857 0.872853235735237 1 GO:0015179 L-amino acid transmembrane transporter activity 7/2936 62/18639 0.112903225806452 0.71675859189593 0.876431226498602 1 GO:0004407 histone deacetylase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0032931 histone H3K56 acetyltransferase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0033558 protein lysine deacetylase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0043992 histone H3K9 acetyltransferase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0043993 histone H3K18 acetyltransferase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0043994 histone H3K23 acetyltransferase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0043999 histone H2AK5 acetyltransferase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0044012 histone H2AK9 acetyltransferase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0044014 histone H2BK5 acetyltransferase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0044015 histone H2BK12 acetyltransferase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0044016 histone H3K4 acetyltransferase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0044017 histone H3K27 acetyltransferase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0044018 histone H3K36 acetyltransferase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0046972 histone H4K16 acetyltransferase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0050321 tau-protein kinase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0061133 endopeptidase activator activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0140908 histone H3K122 acetyltransferase activity 2/2936 22/18639 0.0909090909090909 0.577130294773347 0.882378489071435 1 GO:0140938 histone H3 methyltransferase activity 5/2936 47/18639 0.106382978723404 0.675365238564555 0.882460245322136 1 GO:0035173 histone kinase activity 49/2936 360/18639 0.136111111111111 0.864092302452316 0.886280269128572 1 GO:0008327 methyl-CpG binding 3/2936 31/18639 0.0967741935483871 0.614364507339369 0.88668446789485 1 GO:0140457 protein demethylase activity 3/2936 31/18639 0.0967741935483871 0.614364507339369 0.88668446789485 1 GO:0003964 RNA-directed DNA polymerase activity 1/2936 13/18639 0.0769230769230769 0.48834101865437 0.892368270360368 1 GO:0004465 lipoprotein lipase activity 1/2936 13/18639 0.0769230769230769 0.48834101865437 0.892368270360368 1 GO:0004535 poly(A)-specific ribonuclease activity 1/2936 13/18639 0.0769230769230769 0.48834101865437 0.892368270360368 1 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/2936 13/18639 0.0769230769230769 0.48834101865437 0.892368270360368 1 GO:0008417 fucosyltransferase activity 1/2936 13/18639 0.0769230769230769 0.48834101865437 0.892368270360368 1 GO:0030955 potassium ion binding 1/2936 13/18639 0.0769230769230769 0.48834101865437 0.892368270360368 1 GO:0035673 oligopeptide transmembrane transporter activity 1/2936 13/18639 0.0769230769230769 0.48834101865437 0.892368270360368 1 GO:0046975 histone H3K36 methyltransferase activity 1/2936 13/18639 0.0769230769230769 0.48834101865437 0.892368270360368 1 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/2936 13/18639 0.0769230769230769 0.48834101865437 0.892368270360368 1 GO:0071714 icosanoid transmembrane transporter activity 1/2936 13/18639 0.0769230769230769 0.48834101865437 0.892368270360368 1 GO:0071837 HMG box domain binding 1/2936 13/18639 0.0769230769230769 0.48834101865437 0.892368270360368 1 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/2936 13/18639 0.0769230769230769 0.48834101865437 0.892368270360368 1 GO:0140666 annealing activity 1/2936 13/18639 0.0769230769230769 0.48834101865437 0.892368270360368 1 GO:0038187 pattern recognition receptor activity 5/2936 48/18639 0.104166666666667 0.661295129427793 0.893346696284239 1 GO:0050997 quaternary ammonium group binding 4/2936 40/18639 0.1 0.634843324250681 0.894618496366794 1 GO:0061791 GTPase motor activity 4/2936 40/18639 0.1 0.634843324250681 0.894618496366794 1 GO:1990606 membrane scission GTPase motor activity 4/2936 40/18639 0.1 0.634843324250681 0.894618496366794 1 GO:0004536 DNA nuclease activity 7/2936 64/18639 0.109375 0.694359885899183 0.895794394711221 1 GO:0005267 potassium channel activity 15/2936 124/18639 0.120967741935484 0.767955634174211 0.896812345195596 1 GO:0000295 adenine nucleotide transmembrane transporter activity 2/2936 23/18639 0.0869565217391304 0.552037673261462 0.897299181866422 1 GO:0005158 insulin receptor binding 2/2936 23/18639 0.0869565217391304 0.552037673261462 0.897299181866422 1 GO:0016917 GABA receptor activity 2/2936 23/18639 0.0869565217391304 0.552037673261462 0.897299181866422 1 GO:0016757 glycosyltransferase activity 35/2936 267/18639 0.131086142322097 0.832191623549582 0.901915465372674 1 GO:0004674 protein serine/threonine kinase activity 59/2936 433/18639 0.136258660508083 0.865029009948965 0.904307946430561 1 GO:0004705 JUN kinase activity 1/2936 14/18639 0.0714285714285714 0.453459517321915 0.909334165250412 1 GO:0008559 ABC-type xenobiotic transporter activity 1/2936 14/18639 0.0714285714285714 0.453459517321915 0.909334165250412 1 GO:0015926 glucosidase activity 1/2936 14/18639 0.0714285714285714 0.453459517321915 0.909334165250412 1 GO:0019763 immunoglobulin receptor activity 1/2936 14/18639 0.0714285714285714 0.453459517321915 0.909334165250412 1 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/2936 14/18639 0.0714285714285714 0.453459517321915 0.909334165250412 1 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/2936 14/18639 0.0714285714285714 0.453459517321915 0.909334165250412 1 GO:0046030 inositol trisphosphate phosphatase activity 1/2936 14/18639 0.0714285714285714 0.453459517321915 0.909334165250412 1 GO:0061783 peptidoglycan muralytic activity 1/2936 14/18639 0.0714285714285714 0.453459517321915 0.909334165250412 1 GO:0070742 C2H2 zinc finger domain binding 1/2936 14/18639 0.0714285714285714 0.453459517321915 0.909334165250412 1 GO:1901474 azole transmembrane transporter activity 1/2936 14/18639 0.0714285714285714 0.453459517321915 0.909334165250412 1 GO:0015295 solute:proton symporter activity 2/2936 24/18639 0.0833333333333333 0.529036103542234 0.910439601157386 1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/2936 24/18639 0.0833333333333333 0.529036103542234 0.910439601157386 1 GO:0043998 histone H2A acetyltransferase activity 2/2936 24/18639 0.0833333333333333 0.529036103542234 0.910439601157386 1 GO:0070840 dynein complex binding 2/2936 24/18639 0.0833333333333333 0.529036103542234 0.910439601157386 1 GO:0140612 DNA damage sensor activity 2/2936 24/18639 0.0833333333333333 0.529036103542234 0.910439601157386 1 GO:0015605 organophosphate ester transmembrane transporter activity 5/2936 50/18639 0.1 0.634843324250681 0.912526020302954 1 GO:0048029 monosaccharide binding 8/2936 74/18639 0.108108108108108 0.686317107298034 0.913897016243548 1 GO:0016887 ATP hydrolysis activity 56/2936 417/18639 0.134292565947242 0.852547389881011 0.919230369901664 1 GO:0008175 tRNA methyltransferase activity 3/2936 34/18639 0.0882352941176471 0.560155874338836 0.920774279596199 1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 3/2936 34/18639 0.0882352941176471 0.560155874338836 0.920774279596199 1 GO:0051427 hormone receptor binding 3/2936 34/18639 0.0882352941176471 0.560155874338836 0.920774279596199 1 GO:0000030 mannosyltransferase activity 2/2936 25/18639 0.08 0.507874659400545 0.921990169207086 1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/2936 25/18639 0.08 0.507874659400545 0.921990169207086 1 GO:0017056 structural constituent of nuclear pore 2/2936 25/18639 0.08 0.507874659400545 0.921990169207086 1 GO:0042974 nuclear retinoic acid receptor binding 2/2936 25/18639 0.08 0.507874659400545 0.921990169207086 1 GO:0004497 monooxygenase activity 12/2936 106/18639 0.113207547169811 0.718690555755488 0.922861536709251 1 GO:0004559 alpha-mannosidase activity 1/2936 15/18639 0.0666666666666667 0.423228882833787 0.923626508381944 1 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/2936 15/18639 0.0666666666666667 0.423228882833787 0.923626508381944 1 GO:0015116 sulfate transmembrane transporter activity 1/2936 15/18639 0.0666666666666667 0.423228882833787 0.923626508381944 1 GO:0017081 chloride channel regulator activity 1/2936 15/18639 0.0666666666666667 0.423228882833787 0.923626508381944 1 GO:0030553 cGMP binding 1/2936 15/18639 0.0666666666666667 0.423228882833787 0.923626508381944 1 GO:0034483 heparan sulfate sulfotransferase activity 1/2936 15/18639 0.0666666666666667 0.423228882833787 0.923626508381944 1 GO:0042809 nuclear vitamin D receptor binding 1/2936 15/18639 0.0666666666666667 0.423228882833787 0.923626508381944 1 GO:0050780 dopamine receptor binding 1/2936 15/18639 0.0666666666666667 0.423228882833787 0.923626508381944 1 GO:0061578 K63-linked deubiquitinase activity 1/2936 15/18639 0.0666666666666667 0.423228882833787 0.923626508381944 1 GO:0141050 histone H3K deacetylase activity 1/2936 15/18639 0.0666666666666667 0.423228882833787 0.923626508381944 1 GO:0141051 histone H4K deacetylase activity 1/2936 15/18639 0.0666666666666667 0.423228882833787 0.923626508381944 1 GO:0035591 signaling adaptor activity 15/2936 129/18639 0.116279069767442 0.738189911919397 0.925705527605456 1 GO:0101005 deubiquitinase activity 13/2936 115/18639 0.11304347826087 0.7176489752399 0.930596024680709 1 GO:0004435 phosphatidylinositol phospholipase C activity 2/2936 26/18639 0.0769230769230769 0.48834101865437 0.932125512397431 1 GO:0008066 glutamate receptor activity 2/2936 26/18639 0.0769230769230769 0.48834101865437 0.932125512397431 1 GO:0015216 purine nucleotide transmembrane transporter activity 2/2936 26/18639 0.0769230769230769 0.48834101865437 0.932125512397431 1 GO:0003724 RNA helicase activity 8/2936 77/18639 0.103896103896104 0.659577479740967 0.933460838492138 1 GO:0004843 cysteine-type deubiquitinase activity 12/2936 108/18639 0.111111111111111 0.705381471389646 0.933493952249999 1 GO:0019905 syntaxin binding 6/2936 61/18639 0.0983606557377049 0.624436056640014 0.933856213430193 1 GO:0016758 hexosyltransferase activity 24/2936 197/18639 0.121827411167513 0.773413186904383 0.934671734094996 1 GO:0003688 DNA replication origin binding 1/2936 16/18639 0.0625 0.396777077656676 0.93566648751589 1 GO:0004707 MAP kinase activity 1/2936 16/18639 0.0625 0.396777077656676 0.93566648751589 1 GO:0022841 potassium ion leak channel activity 1/2936 16/18639 0.0625 0.396777077656676 0.93566648751589 1 GO:0022858 alanine transmembrane transporter activity 1/2936 16/18639 0.0625 0.396777077656676 0.93566648751589 1 GO:0030275 LRR domain binding 1/2936 16/18639 0.0625 0.396777077656676 0.93566648751589 1 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/2936 16/18639 0.0625 0.396777077656676 0.93566648751589 1 GO:0000993 RNA polymerase II complex binding 3/2936 36/18639 0.0833333333333333 0.529036103542234 0.937986107676635 1 GO:0004033 aldo-keto reductase (NADPH) activity 3/2936 36/18639 0.0833333333333333 0.529036103542234 0.937986107676635 1 GO:0004190 aspartic-type endopeptidase activity 3/2936 36/18639 0.0833333333333333 0.529036103542234 0.937986107676635 1 GO:0004620 phospholipase activity 12/2936 109/18639 0.110091743119266 0.698910081743869 0.938321496457657 1 GO:0005261 monoatomic cation channel activity 44/2936 341/18639 0.129032258064516 0.819152676452492 0.94032587873496 1 GO:0005385 zinc ion transmembrane transporter activity 2/2936 27/18639 0.0740740740740741 0.470254314259764 0.941004711221731 1 GO:0008395 steroid hydroxylase activity 2/2936 27/18639 0.0740740740740741 0.470254314259764 0.941004711221731 1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/2936 27/18639 0.0740740740740741 0.470254314259764 0.941004711221731 1 GO:0008186 ATP-dependent activity, acting on RNA 8/2936 79/18639 0.10126582278481 0.642879315696892 0.944237350943172 1 GO:0070001 aspartic-type peptidase activity 3/2936 37/18639 0.0810810810810811 0.514737830473525 0.945229456424601 1 GO:0004659 prenyltransferase activity 1/2936 17/18639 0.0588235294117647 0.373437249559224 0.945808956111355 1 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/2936 17/18639 0.0588235294117647 0.373437249559224 0.945808956111355 1 GO:0009881 photoreceptor activity 1/2936 17/18639 0.0588235294117647 0.373437249559224 0.945808956111355 1 GO:0017110 nucleoside diphosphate phosphatase activity 1/2936 17/18639 0.0588235294117647 0.373437249559224 0.945808956111355 1 GO:0045125 bioactive lipid receptor activity 1/2936 17/18639 0.0588235294117647 0.373437249559224 0.945808956111355 1 GO:0005253 monoatomic anion channel activity 11/2936 103/18639 0.106796116504854 0.677988016190048 0.945972601270459 1 GO:0140713 histone chaperone activity 19/2936 164/18639 0.115853658536585 0.735489217119692 0.947595756434756 1 GO:0005242 inward rectifier potassium channel activity 2/2936 28/18639 0.0714285714285714 0.453459517321915 0.948771863384767 1 GO:0015297 antiporter activity 15/2936 135/18639 0.111111111111111 0.705381471389646 0.95108272343677 1 GO:0061749 forked DNA-dependent helicase activity 4/2936 47/18639 0.0851063829787234 0.540292190851644 0.951491928912661 1 GO:0140359 ABC-type transporter activity 4/2936 47/18639 0.0851063829787234 0.540292190851644 0.951491928912661 1 GO:1990518 single-stranded 3'-5' DNA helicase activity 4/2936 47/18639 0.0851063829787234 0.540292190851644 0.951491928912661 1 GO:0042887 amide transmembrane transporter activity 3/2936 38/18639 0.0789473684210526 0.501192098092643 0.951679382187852 1 GO:0004970 glutamate-gated receptor activity 1/2936 18/18639 0.0555555555555556 0.352690735694823 0.95435287754069 1 GO:0015280 ligand-gated sodium channel activity 1/2936 18/18639 0.0555555555555556 0.352690735694823 0.95435287754069 1 GO:0022851 GABA-gated chloride ion channel activity 1/2936 18/18639 0.0555555555555556 0.352690735694823 0.95435287754069 1 GO:0099094 ligand-gated monoatomic cation channel activity 15/2936 136/18639 0.110294117647059 0.700194842923545 0.954483368635695 1 GO:0004629 phospholipase C activity 2/2936 29/18639 0.0689655172413793 0.437822982241849 0.95555685522527 1 GO:0009378 four-way junction helicase activity 4/2936 48/18639 0.0833333333333333 0.529036103542234 0.956777859151608 1 GO:0036121 double-stranded DNA helicase activity 4/2936 48/18639 0.0833333333333333 0.529036103542234 0.956777859151608 1 GO:0043138 3'-5' DNA helicase activity 4/2936 48/18639 0.0833333333333333 0.529036103542234 0.956777859151608 1 GO:0000149 SNARE binding 11/2936 106/18639 0.10377358490566 0.658799676109198 0.957610032529099 1 GO:0015932 nucleobase-containing compound transmembrane transporter activity 5/2936 57/18639 0.087719298245614 0.556880108991826 0.957861207191284 1 GO:0003756 protein disulfide isomerase activity 1/2936 19/18639 0.0526315789473684 0.334128065395095 0.961550125354477 1 GO:0004890 GABA-A receptor activity 1/2936 19/18639 0.0526315789473684 0.334128065395095 0.961550125354477 1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/2936 19/18639 0.0526315789473684 0.334128065395095 0.961550125354477 1 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/2936 19/18639 0.0526315789473684 0.334128065395095 0.961550125354477 1 GO:0031420 alkali metal ion binding 1/2936 19/18639 0.0526315789473684 0.334128065395095 0.961550125354477 1 GO:0034987 immunoglobulin receptor binding 1/2936 19/18639 0.0526315789473684 0.334128065395095 0.961550125354477 1 GO:0046527 glucosyltransferase activity 1/2936 19/18639 0.0526315789473684 0.334128065395095 0.961550125354477 1 GO:0046624 sphingolipid transporter activity 1/2936 19/18639 0.0526315789473684 0.334128065395095 0.961550125354477 1 GO:0008173 RNA methyltransferase activity 6/2936 67/18639 0.0895522388059701 0.568516409776729 0.963731265697034 1 GO:0005184 neuropeptide hormone activity 2/2936 31/18639 0.0645161290322581 0.409576338226246 0.96663431666019 1 GO:0072349 modified amino acid transmembrane transporter activity 2/2936 31/18639 0.0645161290322581 0.409576338226246 0.96663431666019 1 GO:0106310 protein serine kinase activity 45/2936 361/18639 0.124653739612188 0.791355944356805 0.96747144883092 1 GO:0005326 neurotransmitter transmembrane transporter activity 1/2936 20/18639 0.05 0.317421662125341 0.96761289828462 1 GO:0140664 ATP-dependent DNA damage sensor activity 1/2936 20/18639 0.05 0.317421662125341 0.96761289828462 1 GO:0140939 histone H4 methyltransferase activity 1/2936 20/18639 0.05 0.317421662125341 0.96761289828462 1 GO:0004520 DNA endonuclease activity 3/2936 42/18639 0.0714285714285714 0.453459517321915 0.971017381326123 1 GO:0015106 bicarbonate transmembrane transporter activity 2/2936 32/18639 0.0625 0.396777077656676 0.971123905115148 1 GO:0160041 neuropeptide activity 2/2936 32/18639 0.0625 0.396777077656676 0.971123905115148 1 GO:0046943 carboxylic acid transmembrane transporter activity 21/2936 188/18639 0.111702127659574 0.709133500492782 0.971131412044791 1 GO:0140658 ATP-dependent chromatin remodeler activity 17/2936 158/18639 0.107594936708861 0.683059272927948 0.972025380570327 1 GO:0005248 voltage-gated sodium channel activity 1/2936 21/18639 0.0476190476190476 0.302306344881277 0.972719967978822 1 GO:0015125 bile acid transmembrane transporter activity 1/2936 21/18639 0.0476190476190476 0.302306344881277 0.972719967978822 1 GO:0005342 organic acid transmembrane transporter activity 21/2936 189/18639 0.111111111111111 0.705381471389646 0.973015292308079 1 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 4/2936 52/18639 0.0769230769230769 0.48834101865437 0.97302258215519 1 GO:0000510 H3-H4 histone complex chaperone activity 16/2936 151/18639 0.105960264900662 0.672681668080192 0.9734778320538 1 GO:0140584 chromatin extrusion motor activity 16/2936 151/18639 0.105960264900662 0.672681668080192 0.9734778320538 1 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 16/2936 151/18639 0.105960264900662 0.672681668080192 0.9734778320538 1 GO:0140849 ATP-dependent H2AZ histone chaperone activity 16/2936 151/18639 0.105960264900662 0.672681668080192 0.9734778320538 1 GO:0016782 transferase activity, transferring sulphur-containing groups 6/2936 70/18639 0.0857142857142857 0.544151420786298 0.973481825640009 1 GO:0005245 voltage-gated calcium channel activity 3/2936 43/18639 0.0697674418604651 0.442913947151638 0.974552681337859 1 GO:0015616 DNA translocase activity 16/2936 152/18639 0.105263157894737 0.668256130790191 0.975406327776478 1 GO:0140674 ATP-dependent histone chaperone activity 16/2936 152/18639 0.105263157894737 0.668256130790191 0.975406327776478 1 GO:0008146 sulfotransferase activity 4/2936 53/18639 0.0754716981132075 0.479127037170325 0.976076514179509 1 GO:0033038 bitter taste receptor activity 1/2936 22/18639 0.0454545454545455 0.288565147386673 0.977021943164888 1 GO:0061775 cohesin loader activity 16/2936 153/18639 0.104575163398693 0.663888443660843 0.977208018261317 1 GO:1901682 sulfur compound transmembrane transporter activity 5/2936 63/18639 0.0793650793650794 0.503843908135461 0.978329840148598 1 GO:0016298 lipase activity 13/2936 130/18639 0.1 0.634843324250681 0.978343512660672 1 GO:0090482 vitamin transmembrane transporter activity 2/2936 34/18639 0.0588235294117647 0.373437249559224 0.978418382170246 1 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 61/2936 484/18639 0.12603305785124 0.800112454117594 0.979090841333591 1 GO:0003887 DNA-directed DNA polymerase activity 1/2936 23/18639 0.0434782608695652 0.276018836630731 0.980645705042091 1 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/2936 23/18639 0.0434782608695652 0.276018836630731 0.980645705042091 1 GO:0005283 amino acid:sodium symporter activity 1/2936 23/18639 0.0434782608695652 0.276018836630731 0.980645705042091 1 GO:0031681 G-protein beta-subunit binding 1/2936 23/18639 0.0434782608695652 0.276018836630731 0.980645705042091 1 GO:0034061 DNA polymerase activity 2/2936 35/18639 0.0571428571428571 0.362767613857532 0.981361027863202 1 GO:0008509 monoatomic anion transmembrane transporter activity 15/2936 149/18639 0.100671140939597 0.639104017702028 0.983165780416729 1 GO:0019957 C-C chemokine binding 1/2936 24/18639 0.0416666666666667 0.264518051771117 0.983698144341426 1 GO:0005216 monoatomic ion channel activity 55/2936 448/18639 0.122767857142857 0.779383545397042 0.984817201188778 1 GO:0001216 DNA-binding transcription activator activity 61/2936 491/18639 0.124236252545825 0.788705555586386 0.984905008398784 1 GO:0099095 ligand-gated monoatomic anion channel activity 3/2936 47/18639 0.0638297872340425 0.405219143138733 0.984998923458352 1 GO:0005251 delayed rectifier potassium channel activity 1/2936 25/18639 0.04 0.253937329700272 0.986269309972024 1 GO:0005537 D-mannose binding 1/2936 25/18639 0.04 0.253937329700272 0.986269309972024 1 GO:0015271 outward rectifier potassium channel activity 1/2936 25/18639 0.04 0.253937329700272 0.986269309972024 1 GO:0003689 DNA clamp loader activity 16/2936 160/18639 0.1 0.634843324250681 0.986830946624952 1 GO:0008188 neuropeptide receptor activity 3/2936 48/18639 0.0625 0.396777077656676 0.986880327745468 1 GO:0017116 single-stranded DNA helicase activity 4/2936 58/18639 0.0689655172413793 0.437822982241849 0.987041450079736 1 GO:0035402 histone H3T11 kinase activity 27/2936 247/18639 0.109311740890688 0.693958289666737 0.98838400760146 1 GO:0015108 chloride transmembrane transporter activity 11/2936 121/18639 0.0909090909090909 0.577130294773347 0.988569027983935 1 GO:0005104 fibroblast growth factor receptor binding 1/2936 27/18639 0.037037037037037 0.235127157129882 0.990259306130903 1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 26/2936 243/18639 0.106995884773663 0.679256231708548 0.990938149033141 1 GO:0015144 carbohydrate transmembrane transporter activity 2/2936 40/18639 0.05 0.317421662125341 0.991122595310894 1 GO:0030331 nuclear estrogen receptor binding 2/2936 40/18639 0.05 0.317421662125341 0.991122595310894 1 GO:0015103 inorganic anion transmembrane transporter activity 16/2936 165/18639 0.096969696969697 0.615605647758236 0.991244447468061 1 GO:0008527 taste receptor activity 1/2936 28/18639 0.0357142857142857 0.226729758660958 0.991795878084463 1 GO:0050698 proteoglycan sulfotransferase activity 1/2936 28/18639 0.0357142857142857 0.226729758660958 0.991795878084463 1 GO:0003823 antigen binding 17/2936 174/18639 0.0977011494252874 0.62024922484262 0.991905734846098 1 GO:0004676 3-phosphoinositide-dependent protein kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0004711 ribosomal protein S6 kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0035175 histone H3S10 kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0035979 histone H2AXS139 kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0044022 histone H3S28 kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0044023 histone H4S1 kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0044024 histone H2AS1 kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0044025 histone H2BS14 kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0072354 histone H3T3 kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0072371 histone H2AS121 kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0072518 Rho-dependent protein serine/threonine kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0140823 histone H2BS36 kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0140855 histone H3S57 kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0140995 histone H2A kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0140997 histone H4 kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0140998 histone H2B kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:1990244 histone H2AT120 kinase activity 26/2936 245/18639 0.106122448979592 0.673711282878274 0.99212068031669 1 GO:0004677 DNA-dependent protein kinase activity 26/2936 246/18639 0.105691056910569 0.670972619126736 0.992657203511469 1 GO:0140857 histone H3T45 kinase activity 26/2936 246/18639 0.105691056910569 0.670972619126736 0.992657203511469 1 GO:0005416 amino acid:monoatomic cation symporter activity 1/2936 29/18639 0.0344827586206897 0.218911491120925 0.993090128900863 1 GO:0035403 histone H3T6 kinase activity 26/2936 247/18639 0.105263157894737 0.668256130790191 0.993159932442059 1 GO:1901505 carbohydrate derivative transmembrane transporter activity 3/2936 53/18639 0.0566037735849057 0.359345277877744 0.993353918551557 1 GO:0004679 AMP-activated protein kinase activity 26/2936 248/18639 0.104838709677419 0.66556154961765 0.993630775272749 1 GO:0005254 chloride channel activity 6/2936 83/18639 0.072289156626506 0.458922885000492 0.993711395637602 1 GO:0015291 secondary active transmembrane transporter activity 31/2936 287/18639 0.10801393728223 0.685719270096555 0.993878350543139 1 GO:0001653 peptide receptor activity 11/2936 128/18639 0.0859375 0.545568481777929 0.99409805517289 1 GO:0015171 amino acid transmembrane transporter activity 8/2936 102/18639 0.0784313725490196 0.497916332745632 0.994213442111999 1 GO:0005452 solute:inorganic anion antiporter activity 1/2936 31/18639 0.032258064516129 0.204788169113123 0.995098460431864 1 GO:0008528 G protein-coupled peptide receptor activity 10/2936 122/18639 0.0819672131147541 0.520363380533345 0.995451952633871 1 GO:0005244 voltage-gated monoatomic ion channel activity 16/2936 173/18639 0.092485549132948 0.587138334567104 0.995562476920371 1 GO:0042910 xenobiotic transmembrane transporter activity 1/2936 32/18639 0.03125 0.198388538828338 0.995871833184016 1 GO:0022832 voltage-gated channel activity 16/2936 175/18639 0.0914285714285714 0.580428182172051 0.996273934147053 1 GO:0042923 neuropeptide binding 1/2936 33/18639 0.0303030303030303 0.192376764924449 0.996523216952046 1 GO:0005249 voltage-gated potassium channel activity 7/2936 98/18639 0.0714285714285714 0.453459517321915 0.996712369592757 1 GO:0008094 ATP-dependent activity, acting on DNA 20/2936 210/18639 0.0952380952380952 0.604612689762554 0.996925638027396 1 GO:0140097 catalytic activity, acting on DNA 36/2936 336/18639 0.107142857142857 0.680189275982873 0.997036927897862 1 GO:0015020 glucuronosyltransferase activity 1/2936 34/18639 0.0294117647058824 0.186718624779612 0.99707184830907 1 GO:0005343 organic acid:sodium symporter activity 1/2936 35/18639 0.0285714285714286 0.181383806928766 0.99753393126336 1 GO:0140299 molecular sensor activity 4/2936 71/18639 0.0563380281690141 0.357658210845454 0.997572048140505 1 GO:0004386 helicase activity 13/2936 155/18639 0.0838709677419355 0.53244923969412 0.997713860169068 1 GO:0015081 sodium ion transmembrane transporter activity 14/2936 164/18639 0.0853658536585366 0.541939423140825 0.997804417393167 1 GO:0046873 metal ion transmembrane transporter activity 50/2936 450/18639 0.111111111111111 0.705381471389646 0.998226089628303 1 GO:0003678 DNA helicase activity 4/2936 74/18639 0.0540540540540541 0.343158553649017 0.998372660997041 1 GO:0015276 ligand-gated monoatomic ion channel activity 16/2936 186/18639 0.0860215053763441 0.546101784301661 0.998620219642918 1 GO:0008514 organic anion transmembrane transporter activity 26/2936 269/18639 0.0966542750929368 0.613603213030398 0.998694769417372 1 GO:0015294 solute:monoatomic cation symporter activity 8/2936 116/18639 0.0689655172413793 0.437822982241849 0.998766646844004 1 GO:0022834 ligand-gated channel activity 16/2936 188/18639 0.0851063829787234 0.540292190851644 0.998854663725999 1 GO:0015370 solute:sodium symporter activity 4/2936 79/18639 0.0506329113924051 0.321439657848446 0.999172528505016 1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/2936 56/18639 0.0357142857142857 0.226729758660958 0.999231567473804 1 GO:0003730 mRNA 3'-UTR binding 24/2936 262/18639 0.0916030534351145 0.581535869542609 0.999388478434231 1 GO:0022843 voltage-gated monoatomic cation channel activity 10/2936 143/18639 0.0699300699300699 0.443946380594882 0.99951061408482 1 GO:0015293 symporter activity 10/2936 146/18639 0.0684931506849315 0.434824194692247 0.999649849254595 1 GO:0030594 neurotransmitter receptor activity 5/2936 97/18639 0.0515463917525773 0.327238826933341 0.999684653425693 1 GO:0022824 transmitter-gated monoatomic ion channel activity 2/2936 63/18639 0.0317460317460317 0.201537563254184 0.999743056132679 1 GO:0022835 transmitter-gated channel activity 2/2936 63/18639 0.0317460317460317 0.201537563254184 0.999743056132679 1 GO:0005179 hormone activity 8/2936 132/18639 0.0606060606060606 0.384753529848898 0.999812108387819 1 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/2936 53/18639 0.0188679245283019 0.119781759292581 0.99988814237126 1 GO:0098960 postsynaptic neurotransmitter receptor activity 2/2936 69/18639 0.0289855072463768 0.184012557753821 0.999900416252359 1 GO:0022836 gated channel activity 28/2936 318/18639 0.0880503144654088 0.55898154336538 0.999914053823957 1 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/2936 73/18639 0.0273972602739726 0.173929677876899 0.99994726925602 1 GO:0045182 translation regulator activity 18/2936 356/18639 0.050561797752809 0.320988197654839 0.999999999941174 1 GO:0030371 translation repressor activity 11/2936 329/18639 0.033434650455927 0.212257646406003 0.99999999999995 1 GO:0004984 olfactory receptor activity 4/2936 419/18639 0.00954653937947494 0.0606055679475591 1 1