ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0031267	small GTPase binding	169/6090	283/18639	0.597173144876325	1.82770283207715	5.08689566422835e-21	6.98939464264976e-18
GO:0051020	GTPase binding	181/6090	315/18639	0.574603174603175	1.75862538118696	7.26572105081869e-20	4.99155036191244e-17
GO:0004674	protein serine/threonine kinase activity	229/6090	433/18639	0.528868360277136	1.61864981399106	1.38934914994873e-18	5.90159558515475e-16
GO:0106310	protein serine kinase activity	198/6090	361/18639	0.548476454293629	1.67866217267306	1.71807731736674e-18	5.90159558515475e-16
GO:0030695	GTPase regulator activity	249/6090	489/18639	0.50920245398773	1.5584605155792	2.28547094379562e-17	6.28047415355037e-15
GO:0060589	nucleoside-triphosphatase regulator activity	249/6090	490/18639	0.508163265306122	1.55527998391475	3.16238180025629e-17	7.24185432258691e-15
GO:0004679	AMP-activated protein kinase activity	142/6090	248/18639	0.57258064516129	1.75243524551089	1.0495949074634e-15	1.06541825677446e-13
GO:0140857	histone H3T45 kinase activity	141/6090	246/18639	0.573170731707317	1.75424125916136	1.17700580921453e-15	1.06541825677446e-13
GO:0035402	histone H3T11 kinase activity	141/6090	247/18639	0.57085020242915	1.74713906782872	1.86514870653583e-15	1.06541825677446e-13
GO:0035403	histone H3T6 kinase activity	141/6090	247/18639	0.57085020242915	1.74713906782872	1.86514870653583e-15	1.06541825677446e-13
GO:0004676	3-phosphoinositide-dependent protein kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0004711	ribosomal protein S6 kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0035175	histone H3S10 kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0035979	histone H2AXS139 kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0044022	histone H3S28 kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0044023	histone H4S1 kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0044024	histone H2AS1 kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0044025	histone H2BS14 kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0072354	histone H3T3 kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0072371	histone H2AS121 kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0072518	Rho-dependent protein serine/threonine kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0140823	histone H2BS36 kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0140855	histone H3S57 kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0140995	histone H2A kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0140997	histone H4 kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0140998	histone H2B kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:1990244	histone H2AT120 kinase activity	140/6090	245/18639	0.571428571428571	1.74890921885996	2.09361666178388e-15	1.06541825677446e-13
GO:0004677	DNA-dependent protein kinase activity	140/6090	246/18639	0.569105691056911	1.74179983179142	3.30423476895083e-15	1.62143520447802e-13
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	138/6090	243/18639	0.567901234567901	1.73811348294107	6.56289489841885e-15	3.10945434152673e-13
GO:0141003	histone H2AX kinase activity	184/6090	354/18639	0.519774011299435	1.59081573014945	2.99130266328598e-14	1.37001661978498e-12
GO:0140996	histone H3 kinase activity	185/6090	357/18639	0.518207282913165	1.58602061514261	3.69005695801999e-14	1.6355284710708e-12
GO:0035173	histone kinase activity	185/6090	360/18639	0.513888888888889	1.57280377668309	1.01945243427778e-13	4.37727388968023e-12
GO:0035091	phosphatidylinositol binding	152/6090	284/18639	0.535211267605634	1.63806285991813	2.42279002897931e-13	1.00876166661138e-11
GO:0019787	ubiquitin-like protein transferase activity	225/6090	479/18639	0.46972860125261	1.43764719191254	3.21873831199021e-11	1.30074895313957e-09
GO:0005096	GTPase activator activity	140/6090	271/18639	0.516605166051661	1.58111719048225	6.20466426478808e-11	2.43577391423395e-09
GO:0004842	ubiquitin-protein transferase activity	212/6090	449/18639	0.472160356347439	1.44508979999342	6.67841949461193e-11	2.54893010711022e-09
GO:0016755	aminoacyltransferase activity	230/6090	496/18639	0.463709677419355	1.41922572699825	9.0594703008883e-11	3.3642465387623e-09
GO:0003779	actin binding	208/6090	443/18639	0.469525959367946	1.43702698795717	1.87359408416988e-10	6.77452176749847e-09
GO:0003712	transcription coregulator activity	228/6090	495/18639	0.460606060606061	1.40972682489924	2.37303368961726e-10	8.36038022957464e-09
GO:0005543	phospholipid binding	228/6090	497/18639	0.458752515090543	1.40405387992983	3.75269568510679e-10	1.28905096783418e-08
GO:0045296	cadherin binding	162/6090	334/18639	0.48502994011976	1.48447833397245	1.04967032722526e-09	3.51767568196952e-08
GO:0005085	guanyl-nucleotide exchange factor activity	119/6090	230/18639	0.517391304347826	1.58352323838081	1.46515492293545e-09	4.79314967646026e-08
GO:0061659	ubiquitin-like protein ligase activity	175/6090	372/18639	0.470430107526882	1.43979421579533	4.29223327437387e-09	1.37151826023016e-07
GO:0015631	tubulin binding	180/6090	385/18639	0.467532467532468	1.43092572452178	4.64120670490546e-09	1.4493222755773e-07
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	41/6090	60/18639	0.683333333333333	2.0914039408867	1.62014265510256e-08	4.94683557357981e-07
GO:0061630	ubiquitin protein ligase activity	165/6090	353/18639	0.46742209631728	1.43058792335924	2.05548077339426e-08	6.13963170139937e-07
GO:1901981	phosphatidylinositol phosphate binding	96/6090	185/18639	0.518918918918919	1.58819864199175	4.51824763695003e-08	1.32086643684454e-06
GO:0046332	SMAD binding	49/6090	79/18639	0.620253164556962	1.89834133566128	7.99209252646281e-08	2.28773648569998e-06
GO:0019208	phosphatase regulator activity	65/6090	117/18639	0.555555555555556	1.70032840722496	2.69251741624332e-07	7.55003863248636e-06
GO:0005520	insulin-like growth factor binding	17/6090	19/18639	0.894736842105263	2.7384236453202	4.44871675412555e-07	1.2225073640337e-05
GO:0031994	insulin-like growth factor I binding	13/6090	13/18639	1	3.06059113300493	4.79493279490831e-07	1.29181130592236e-05
GO:0003713	transcription coactivator activity	121/6090	256/18639	0.47265625	1.44660752770936	7.38830464401386e-07	1.95221741939905e-05
GO:0001221	transcription coregulator binding	63/6090	115/18639	0.547826086956522	1.67667166416792	7.94010352741825e-07	2.05843438616466e-05
GO:0070064	proline-rich region binding	16/6090	18/18639	0.888888888888889	2.72052545155993	1.22413270470516e-06	3.1147376597498e-05
GO:0008017	microtubule binding	128/6090	276/18639	0.463768115942029	1.41940458342257	1.27810135256432e-06	3.1598360179198e-05
GO:0140297	DNA-binding transcription factor binding	209/6090	488/18639	0.42827868852459	1.31078595655334	1.28785165213616e-06	3.1598360179198e-05
GO:0019888	protein phosphatase regulator activity	59/6090	107/18639	0.551401869158878	1.68761567147001	1.31838110687609e-06	3.17799235236448e-05
GO:0001727	lipid kinase activity	28/6090	41/18639	0.682926829268293	2.09015979814971	3.17773443372352e-06	7.52794329644157e-05
GO:0019209	kinase activator activity	75/6090	148/18639	0.506756756756757	1.55097523632006	4.08773756051385e-06	9.51957865787463e-05
GO:0002162	dystroglycan binding	11/6090	11/18639	1	3.06059113300493	4.50296767385848e-06	0.000103117959731359
GO:0030295	protein kinase activator activity	71/6090	139/18639	0.510791366906475	1.56332352836942	5.08952198682798e-06	0.000114639396883634
GO:0032182	ubiquitin-like protein binding	63/6090	120/18639	0.525	1.60681034482759	5.36440424044228e-06	0.000118882119780124
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	153/6090	349/18639	0.438395415472779	1.341749121346	7.21425723737468e-06	0.000157339514986552
GO:0043130	ubiquitin binding	54/6090	100/18639	0.54	1.65271921182266	8.39533307761223e-06	0.000180237307009988
GO:0019838	growth factor binding	69/6090	136/18639	0.507352941176471	1.55279991306868	9.2578906855883e-06	0.000195697566184589
GO:0050840	extracellular matrix binding	39/6090	67/18639	0.582089552238806	1.7815381221969	1.47850345305172e-05	0.000307797537044403
GO:0140030	modification-dependent protein binding	83/6090	173/18639	0.479768786127168	1.46837609271335	1.92665429869775e-05	0.000395107911404583
GO:0051015	actin filament binding	97/6090	209/18639	0.464114832535885	1.4204657411554	2.2526130711876e-05	0.000455160347031141
GO:0052742	phosphatidylinositol kinase activity	19/6090	26/18639	0.730769230769231	2.23658582796514	2.86640982674632e-05	0.000570789435065137
GO:0019902	phosphatase binding	89/6090	190/18639	0.468421052631579	1.43364532019704	3.12556860891858e-05	0.00061350446695059
GO:0019207	kinase regulator activity	126/6090	287/18639	0.439024390243902	1.34367415595338	4.10105636322684e-05	0.000793641048320236
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	26/6090	41/18639	0.634146341463415	1.94086266971044	5.21358355714243e-05	0.000994925528821347
GO:0051010	microtubule plus-end binding	16/6090	21/18639	0.761904761904762	2.33187895847994	5.45305484257187e-05	0.00102636950050599
GO:0019887	protein kinase regulator activity	113/6090	255/18639	0.443137254901961	1.35626195305708	6.20972611512169e-05	0.00115299509218611
GO:0019211	phosphatase activator activity	18/6090	25/18639	0.72	2.20362561576355	6.48513879505909e-05	0.00118807742725482
GO:0043236	laminin binding	20/6090	29/18639	0.689655172413793	2.11075250552064	6.75767344505338e-05	0.00122171622546097
GO:0032266	phosphatidylinositol-3-phosphate binding	29/6090	48/18639	0.604166666666667	1.84910714285714	7.13568461435871e-05	0.00127330268313362
GO:0003714	transcription corepressor activity	93/6090	204/18639	0.455882352941176	1.39526948710519	7.59261698296576e-05	0.00133746868392243
GO:0042393	histone binding	109/6090	247/18639	0.441295546558704	1.35062523683213	0.000101701375951563	0.00176883152604363
GO:0032452	histone demethylase activity	20/6090	30/18639	0.666666666666667	2.04039408866995	0.00014043172356381	0.00241191485220843
GO:0141052	histone H3 demethylase activity	19/6090	28/18639	0.678571428571429	2.0768296973962	0.000144586790590695	0.00245262037372364
GO:0070063	RNA polymerase binding	33/6090	59/18639	0.559322033898305	1.71185605744343	0.000191363894009827	0.00320651207767686
GO:0004721	phosphoprotein phosphatase activity	80/6090	175/18639	0.457142857142857	1.39912737508797	0.0002079772692066	0.00344290081795022
GO:0140793	histone H2AXY142 phosphatase activity	46/6090	90/18639	0.511111111111111	1.56430213464696	0.000217327340881239	0.00354089784809159
GO:0016922	nuclear receptor binding	65/6090	137/18639	0.474452554744526	1.45210528208263	0.000219051176919786	0.00354089784809159
GO:0005201	extracellular matrix structural constituent	77/6090	168/18639	0.458333333333333	1.40277093596059	0.000244733270880586	0.00391004086267354
GO:0016791	phosphatase activity	117/6090	273/18639	0.428571428571429	1.31168191414497	0.000250210160120735	0.00395159494259643
GO:0071889	14-3-3 protein binding	21/6090	33/18639	0.636363636363636	1.94764890282132	0.000256127353419923	0.00399907935907925
GO:0051213	dioxygenase activity	47/6090	93/18639	0.505376344086022	1.54675035754012	0.000262382539576152	0.00405071471210824
GO:0004725	protein tyrosine phosphatase activity	49/6090	98/18639	0.5	1.53029556650246	0.0002726380462516	0.00414186157926074
GO:0140457	protein demethylase activity	20/6090	31/18639	0.645161290322581	1.97457492451931	0.000274315432105333	0.00414186157926074
GO:0001223	transcription coactivator binding	26/6090	44/18639	0.590909090909091	1.80853112404837	0.000278030994658444	0.00415233246370328
GO:0072542	protein phosphatase activator activity	15/6090	21/18639	0.714285714285714	2.18613652357495	0.000313610027033841	0.00459575817079068
GO:0004709	MAP kinase kinase kinase activity	17/6090	25/18639	0.68	2.08120197044335	0.000314411403241866	0.00459575817079068
GO:0002020	protease binding	64/6090	136/18639	0.470588235294118	1.44027818023761	0.000324061835119323	0.00463813501514531
GO:0140789	histone phosphatase activity	64/6090	136/18639	0.470588235294118	1.44027818023761	0.000324061835119323	0.00463813501514531
GO:0032451	demethylase activity	24/6090	40/18639	0.6	1.83635467980296	0.00034497680034512	0.00480758941313459
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	45/6090	89/18639	0.50561797752809	1.54748989871036	0.000346398363828475	0.00480758941313459
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	45/6090	89/18639	0.50561797752809	1.54748989871036	0.000346398363828475	0.00480758941313459
GO:0035591	signaling adaptor activity	61/6090	129/18639	0.472868217054264	1.44725627219613	0.000376356799479893	0.00517114242485373
GO:0005024	transforming growth factor beta receptor activity	12/6090	16/18639	0.75	2.29544334975369	0.000642050503362704	0.0086487979570623
GO:0070411	I-SMAD binding	12/6090	16/18639	0.75	2.29544334975369	0.000642050503362704	0.0086487979570623
GO:0019903	protein phosphatase binding	66/6090	144/18639	0.458333333333333	1.40277093596059	0.000653053880919865	0.00871161196489218
GO:1902936	phosphatidylinositol bisphosphate binding	53/6090	111/18639	0.477477477477477	1.46136333377713	0.000661995284726123	0.00874597616551628
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	15/6090	22/18639	0.681818181818182	2.08676668159427	0.000687629858093835	0.00891323985868802
GO:0050321	tau-protein kinase activity	15/6090	22/18639	0.681818181818182	2.08676668159427	0.000687629858093835	0.00891323985868802
GO:0031418	L-ascorbic acid binding	14/6090	20/18639	0.7	2.14241379310345	0.000695632257375898	0.00893269833303256
GO:0030276	clathrin binding	26/6090	46/18639	0.565217391304348	1.72989933604626	0.000722834348907293	0.00919605921665389
GO:0005518	collagen binding	37/6090	72/18639	0.513888888888889	1.57280377668309	0.000759587994103031	0.00957498994401436
GO:0043014	alpha-tubulin binding	25/6090	44/18639	0.568181818181818	1.73897223466189	0.000820014038853646	0.0102427208125901
GO:0001217	DNA-binding transcription repressor activity	116/6090	278/18639	0.41726618705036	1.27708119218911	0.0008930449059923	0.011054447755256
GO:0043175	RNA polymerase core enzyme binding	24/6090	42/18639	0.571428571428571	1.74890921885996	0.000929202857517469	0.0113993279127589
GO:0001222	transcription corepressor binding	27/6090	49/18639	0.551020408163265	1.68644817532924	0.000979509684490652	0.0119101443052226
GO:0032050	clathrin heavy chain binding	9/6090	11/18639	0.818181818181818	2.50412001791312	0.00116152873207467	0.0138777432858313
GO:0140537	transcription regulator activator activity	9/6090	11/18639	0.818181818181818	2.50412001791312	0.00116152873207467	0.0138777432858313
GO:0031625	ubiquitin protein ligase binding	124/6090	302/18639	0.410596026490066	1.25666655792255	0.00125607215918827	0.0148779581614197
GO:0008013	beta-catenin binding	50/6090	106/18639	0.471698113207547	1.44367506273817	0.00129765287301785	0.0152391029703122
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	42/6090	86/18639	0.488372093023256	1.49470729751403	0.00131940134003492	0.0153631986543049
GO:0000993	RNA polymerase II complex binding	21/6090	36/18639	0.583333333333333	1.78534482758621	0.00133988717643799	0.0154706300876118
GO:0042578	phosphoric ester hydrolase activity	146/6090	363/18639	0.402203856749311	1.23098155762733	0.00137077549907916	0.0156953794644564
GO:0044389	ubiquitin-like protein ligase binding	131/6090	322/18639	0.406832298136646	1.24514732429704	0.00141786556877609	0.0161003908388293
GO:0048156	tau protein binding	24/6090	43/18639	0.558139534883721	1.70823691144461	0.00145610862190279	0.0163991249712659
GO:0120283	protein serine/threonine kinase binding	11/6090	15/18639	0.733333333333333	2.24443349753695	0.00149462624197094	0.0166960687517729
GO:1990380	K48-linked deubiquitinase activity	13/6090	19/18639	0.684210526315789	2.09408866995074	0.00151495270080475	0.0167866533137559
GO:0008484	sulfuric ester hydrolase activity	12/6090	17/18639	0.705882352941177	2.16041727035642	0.00153261514536443	0.0168465056778458
GO:0140142	nucleocytoplasmic carrier activity	19/6090	32/18639	0.59375	1.81722598522167	0.00169197254905065	0.0184505577967904
GO:0043178	alcohol binding	44/6090	92/18639	0.478260869565217	1.46376097665453	0.00174844359844416	0.0189162323170258
GO:0005516	calmodulin binding	88/6090	207/18639	0.42512077294686	1.30112086813736	0.00182413923995194	0.0195809946538591
GO:0001968	fibronectin binding	18/6090	30/18639	0.6	1.83635467980296	0.00189252811226008	0.0200025663557334
GO:0031624	ubiquitin conjugating enzyme binding	18/6090	30/18639	0.6	1.83635467980296	0.00189252811226008	0.0200025663557334
GO:0051019	mitogen-activated protein kinase binding	17/6090	28/18639	0.607142857142857	1.85821604503871	0.00210829210331563	0.0221129263355395
GO:0140767	enzyme-substrate adaptor activity	62/6090	139/18639	0.446043165467626	1.36515575716766	0.00212721805528016	0.0221424061208707
GO:0043539	protein serine/threonine kinase activator activity	36/6090	73/18639	0.493150684931507	1.50933261353668	0.00228515076571754	0.0236074973841797
GO:0010485	histone H4 acetyltransferase activity	20/6090	35/18639	0.571428571428571	1.74890921885996	0.00244512628783607	0.0248859519961982
GO:0140566	histone reader activity	20/6090	35/18639	0.571428571428571	1.74890921885996	0.00244512628783607	0.0248859519961982
GO:0140033	acetylation-dependent protein binding	15/6090	24/18639	0.625	1.91286945812808	0.0025734835781561	0.0259997532087241
GO:0140034	methylation-dependent protein binding	37/6090	76/18639	0.486842105263158	1.49002463054187	0.00266334118402618	0.0267111736266567
GO:0001786	phosphatidylserine binding	30/6090	59/18639	0.508474576271186	1.55623277949403	0.00285743552425298	0.0284501189153884
GO:0016303	1-phosphatidylinositol-3-kinase activity	8/6090	10/18639	0.8	2.44847290640394	0.00294189710957455	0.0288726187753959
GO:0051864	histone H3K36 demethylase activity	8/6090	10/18639	0.8	2.44847290640394	0.00294189710957455	0.0288726187753959
GO:0015095	magnesium ion transmembrane transporter activity	13/6090	20/18639	0.65	1.9893842364532	0.00303654781002976	0.0295901892977368
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	12/6090	18/18639	0.666666666666667	2.04039408866995	0.0032323173683407	0.0312760849584516
GO:0031543	peptidyl-proline dioxygenase activity	9/6090	12/18639	0.75	2.29544334975369	0.00329291168947745	0.0316395850443497
GO:0005521	lamin binding	11/6090	16/18639	0.6875	2.10415640394089	0.00337029286690905	0.0319364303388485
GO:0034450	ubiquitin-ubiquitin ligase activity	11/6090	16/18639	0.6875	2.10415640394089	0.00337029286690905	0.0319364303388485
GO:0010484	histone H3 acetyltransferase activity	17/6090	29/18639	0.586206896551724	1.79413962969254	0.00355441319414133	0.0334504364982889
GO:0044390	ubiquitin-like protein conjugating enzyme binding	20/6090	36/18639	0.555555555555556	1.70032840722496	0.00382667517708367	0.0357676985939657
GO:0140658	ATP-dependent chromatin remodeler activity	68/6090	158/18639	0.430379746835443	1.31721643698946	0.00396521572507066	0.0368122054476155
GO:0005385	zinc ion transmembrane transporter activity	16/6090	27/18639	0.592592592592593	1.81368363437329	0.00400728262178008	0.0369530625659452
GO:0061775	cohesin loader activity	66/6090	153/18639	0.431372549019608	1.32025499855114	0.00420432483185473	0.0383392164123362
GO:0005178	integrin binding	69/6090	161/18639	0.428571428571429	1.31168191414497	0.00421340733498018	0.0383392164123362
GO:0004812	aminoacyl-tRNA ligase activity	22/6090	41/18639	0.536585365853659	1.64226841283191	0.00437066980226902	0.0390831407274875
GO:0016875	ligase activity, forming carbon-oxygen bonds	22/6090	41/18639	0.536585365853659	1.64226841283191	0.00437066980226902	0.0390831407274875
GO:0052866	phosphatidylinositol phosphate phosphatase activity	19/6090	34/18639	0.558823529411765	1.71033033903216	0.00438049757789889	0.0390831407274875
GO:0000149	SNARE binding	48/6090	106/18639	0.452830188679245	1.38592806022865	0.00445216355318165	0.0394662756262683
GO:0030165	PDZ domain binding	39/6090	83/18639	0.469879518072289	1.43810908659268	0.00455524216651601	0.0401211713896987
GO:0032934	sterol binding	33/6090	68/18639	0.485294117647059	1.48528687337004	0.00469386780775819	0.0410788176296799
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	108/6090	268/18639	0.402985074626866	1.23337254613631	0.00496102186559175	0.0427087101801615
GO:0043425	bHLH transcription factor binding	18/6090	32/18639	0.5625	1.72158251231527	0.00501114299183302	0.0427087101801615
GO:0042171	lysophosphatidic acid acyltransferase activity	14/6090	23/18639	0.608695652173913	1.86296851574213	0.00503552478106708	0.0427087101801615
GO:0070577	lysine-acetylated histone binding	14/6090	23/18639	0.608695652173913	1.86296851574213	0.00503552478106708	0.0427087101801615
GO:0071617	lysophospholipid acyltransferase activity	14/6090	23/18639	0.608695652173913	1.86296851574213	0.00503552478106708	0.0427087101801615
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	13/6090	21/18639	0.619047619047619	1.89465165376495	0.00559896333448058	0.0468439744580287
GO:0010314	phosphatidylinositol-5-phosphate binding	13/6090	21/18639	0.619047619047619	1.89465165376495	0.00559896333448058	0.0468439744580287
GO:0140674	ATP-dependent histone chaperone activity	65/6090	152/18639	0.427631578947368	1.30880541871921	0.00568569488918331	0.0468439744580287
GO:0043995	histone H4K5 acetyltransferase activity	17/6090	30/18639	0.566666666666667	1.73433497536946	0.00572764753198604	0.0468439744580287
GO:0043996	histone H4K8 acetyltransferase activity	17/6090	30/18639	0.566666666666667	1.73433497536946	0.00572764753198604	0.0468439744580287
GO:0043997	histone H4K12 acetyltransferase activity	17/6090	30/18639	0.566666666666667	1.73433497536946	0.00572764753198604	0.0468439744580287
GO:0043394	proteoglycan binding	20/6090	37/18639	0.540540540540541	1.65437358540807	0.00579769907974908	0.0471363226957115
GO:0015485	cholesterol binding	27/6090	54/18639	0.5	1.53029556650246	0.00608692903290528	0.0491967087718344
GO:0035064	methylated histone binding	35/6090	74/18639	0.472972972972973	1.44757688723206	0.00613392609907953	0.0492866342697969
GO:0140036	ubiquitin-modified protein reader activity	12/6090	19/18639	0.631578947368421	1.93300492610837	0.00617637108411664	0.0492924155076339
GO:0031593	polyubiquitin modification-dependent protein binding	29/6090	59/18639	0.491525423728814	1.5043583535109	0.00620639583902523	0.0492924155076339
GO:0019894	kinesin binding	22/6090	42/18639	0.523809523809524	1.60316678395496	0.00637966350572829	0.0503773428555786
GO:0036408	histone H3K14 acetyltransferase activity	16/6090	28/18639	0.571428571428571	1.74890921885996	0.00653926997973268	0.0513426111551583
GO:0061733	protein-lysine-acetyltransferase activity	24/6090	47/18639	0.51063829787234	1.56285504664081	0.00678328324617943	0.0526566733347488
GO:0140938	histone H3 methyltransferase activity	24/6090	47/18639	0.51063829787234	1.56285504664081	0.00678328324617943	0.0526566733347488
GO:0140713	histone chaperone activity	69/6090	164/18639	0.420731707317073	1.28768773278866	0.00707436038939879	0.0546077032305278
GO:0004713	protein tyrosine kinase activity	60/6090	140/18639	0.428571428571429	1.31168191414497	0.00724240477659125	0.0555925372236669
GO:0140104	molecular carrier activity	100/6090	249/18639	0.401606425702811	1.22915306546383	0.00745261697535016	0.0559369098571123
GO:0070412	R-SMAD binding	15/6090	26/18639	0.576923076923077	1.76572565365669	0.00745495330902023	0.0559369098571123
GO:0070123	transforming growth factor beta receptor activity, type III	9/6090	13/18639	0.692307692307692	2.11887078438803	0.00759961656684502	0.0559369098571123
GO:0000510	H3-H4 histone complex chaperone activity	64/6090	151/18639	0.423841059602649	1.29720418882328	0.00762913268531132	0.0559369098571123
GO:0140584	chromatin extrusion motor activity	64/6090	151/18639	0.423841059602649	1.29720418882328	0.00762913268531132	0.0559369098571123
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	64/6090	151/18639	0.423841059602649	1.29720418882328	0.00762913268531132	0.0559369098571123
GO:0140849	ATP-dependent H2AZ histone chaperone activity	64/6090	151/18639	0.423841059602649	1.29720418882328	0.00762913268531132	0.0559369098571123
GO:0003953	NAD+ nucleosidase activity	8/6090	11/18639	0.727272727272727	2.22588446036722	0.00768954611624087	0.0559369098571123
GO:0048185	activin binding	8/6090	11/18639	0.727272727272727	2.22588446036722	0.00768954611624087	0.0559369098571123
GO:0030296	protein tyrosine kinase activator activity	18/6090	33/18639	0.545454545454545	1.66941334527541	0.00769437843012681	0.0559369098571123
GO:0046915	transition metal ion transmembrane transporter activity	23/6090	45/18639	0.511111111111111	1.56430213464696	0.00784851523619825	0.0567571575501915
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	53/6090	122/18639	0.434426229508197	1.32960106597755	0.00812055221263776	0.0584169567547869
GO:0001098	basal transcription machinery binding	29/6090	60/18639	0.483333333333333	1.47928571428571	0.00831730835549874	0.0592123403132397
GO:0001099	basal RNA polymerase II transcription machinery binding	29/6090	60/18639	0.483333333333333	1.47928571428571	0.00831730835549874	0.0592123403132397
GO:0035035	histone acetyltransferase binding	14/6090	24/18639	0.583333333333333	1.78534482758621	0.00848238246514247	0.0597681718313115
GO:0070300	phosphatidic acid binding	14/6090	24/18639	0.583333333333333	1.78534482758621	0.00848238246514247	0.0597681718313115
GO:0070273	phosphatidylinositol-4-phosphate binding	17/6090	31/18639	0.548387096774194	1.67838868584141	0.00886480071353661	0.0621440621448944
GO:0015616	DNA translocase activity	64/6090	152/18639	0.421052631578947	1.28866995073892	0.00904254199158632	0.0630682877991858
GO:0004386	helicase activity	65/6090	155/18639	0.419354838709677	1.28347370093755	0.00951030355186263	0.0659957428295922
GO:0034212	protein N-acetyltransferase activity	26/6090	53/18639	0.490566037735849	1.5014220652477	0.00958380986246508	0.0661331618691326
GO:0140035	ubiquitin-like protein reader activity	13/6090	22/18639	0.590909090909091	1.80853112404837	0.00962636999550693	0.0661331618691326
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	16/6090	29/18639	0.551724137931034	1.68860200441651	0.0102129398696912	0.0691260068027377
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	16/6090	29/18639	0.551724137931034	1.68860200441651	0.0102129398696912	0.0691260068027377
GO:0097472	cyclin-dependent protein kinase activity	16/6090	29/18639	0.551724137931034	1.68860200441651	0.0102129398696912	0.0691260068027377
GO:0008376	acetylgalactosaminyltransferase activity	18/6090	34/18639	0.529411764705882	1.62031295276731	0.0114224943888832	0.0769338592663018
GO:0002039	p53 binding	32/6090	69/18639	0.463768115942029	1.41940458342257	0.0120727606618676	0.0809169421922247
GO:0004706	JUN kinase kinase kinase activity	11/6090	18/18639	0.611111111111111	1.87036124794746	0.0122504493376553	0.0809236412977809
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	11/6090	18/18639	0.611111111111111	1.87036124794746	0.0122504493376553	0.0809236412977809
GO:0098641	cadherin binding involved in cell-cell adhesion	11/6090	18/18639	0.611111111111111	1.87036124794746	0.0122504493376553	0.0809236412977809
GO:0016757	glycosyltransferase activity	105/6090	267/18639	0.393258426966292	1.2036032545525	0.0124773976178423	0.0816652151753279
GO:0019783	ubiquitin-like protein peptidase activity	54/6090	127/18639	0.425196850393701	1.30135371009658	0.0124815831053995	0.0816652151753279
GO:0015662	P-type ion transporter activity	14/6090	25/18639	0.56	1.71393103448276	0.0135481093423671	0.0873948461803401
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	14/6090	25/18639	0.56	1.71393103448276	0.0135481093423671	0.0873948461803401
GO:0140358	P-type transmembrane transporter activity	14/6090	25/18639	0.56	1.71393103448276	0.0135481093423671	0.0873948461803401
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	10/6090	16/18639	0.625	1.91286945812808	0.0136897499472703	0.087895871156773
GO:1990782	protein tyrosine kinase binding	50/6090	117/18639	0.427350427350427	1.30794492863458	0.0141712557275731	0.0905642110217927
GO:0004197	cysteine-type endopeptidase activity	39/6090	88/18639	0.443181818181818	1.35639834303627	0.0146185806560139	0.0924897401288778
GO:0044325	transmembrane transporter binding	57/6090	136/18639	0.419117647058824	1.28274775427412	0.0146254772964819	0.0924897401288778
GO:0004402	histone acetyltransferase activity	21/6090	42/18639	0.5	1.53029556650246	0.0146745002533445	0.0924897401288778
GO:0043495	protein-membrane adaptor activity	23/6090	47/18639	0.48936170212766	1.49773608636411	0.0148743900690606	0.0928757835371918
GO:0140597	protein carrier chaperone	76/6090	188/18639	0.404255319148936	1.23726024525731	0.0149753141878116	0.0928757835371918
GO:0004065	arylsulfatase activity	9/6090	14/18639	0.642857142857143	1.96752287121745	0.0151413213335742	0.0928757835371918
GO:0005545	1-phosphatidylinositol binding	9/6090	14/18639	0.642857142857143	1.96752287121745	0.0151413213335742	0.0928757835371918
GO:0032454	histone H3K9 demethylase activity	9/6090	14/18639	0.642857142857143	1.96752287121745	0.0151413213335742	0.0928757835371918
GO:0034236	protein kinase A catalytic subunit binding	9/6090	14/18639	0.642857142857143	1.96752287121745	0.0151413213335742	0.0928757835371918
GO:0005158	insulin receptor binding	13/6090	23/18639	0.565217391304348	1.72989933604626	0.0155944687742788	0.0944079875107563
GO:0072341	modified amino acid binding	40/6090	91/18639	0.43956043956044	1.34531478373843	0.0157843593337407	0.0944079875107563
GO:0000287	magnesium ion binding	91/6090	230/18639	0.395652173913043	1.21092953523238	0.0159370427331922	0.0944079875107563
GO:0120013	lipid transfer activity	30/6090	65/18639	0.461538461538462	1.41258052292535	0.0159769569640303	0.0944079875107563
GO:0003774	cytoskeletal motor activity	63/6090	153/18639	0.411764705882353	1.26024340770791	0.0163880083116028	0.0944079875107563
GO:0005025	transforming growth factor beta receptor activity, type I	8/6090	12/18639	0.666666666666667	2.04039408866995	0.0164828149697677	0.0944079875107563
GO:0005026	transforming growth factor beta receptor activity, type II	8/6090	12/18639	0.666666666666667	2.04039408866995	0.0164828149697677	0.0944079875107563
GO:0005049	nuclear export signal receptor activity	8/6090	12/18639	0.666666666666667	2.04039408866995	0.0164828149697677	0.0944079875107563
GO:0005165	neurotrophin receptor binding	8/6090	12/18639	0.666666666666667	2.04039408866995	0.0164828149697677	0.0944079875107563
GO:0016361	activin receptor activity, type I	8/6090	12/18639	0.666666666666667	2.04039408866995	0.0164828149697677	0.0944079875107563
GO:0016362	activin receptor activity, type II	8/6090	12/18639	0.666666666666667	2.04039408866995	0.0164828149697677	0.0944079875107563
GO:0017002	activin receptor activity	8/6090	12/18639	0.666666666666667	2.04039408866995	0.0164828149697677	0.0944079875107563
GO:0034452	dynactin binding	8/6090	12/18639	0.666666666666667	2.04039408866995	0.0164828149697677	0.0944079875107563
GO:0035497	cAMP response element binding	8/6090	12/18639	0.666666666666667	2.04039408866995	0.0164828149697677	0.0944079875107563
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	8/6090	12/18639	0.666666666666667	2.04039408866995	0.0164828149697677	0.0944079875107563
GO:0098531	ligand-modulated transcription factor activity	28/6090	60/18639	0.466666666666667	1.42827586206897	0.0164904781678177	0.0944079875107563
GO:0030331	nuclear estrogen receptor binding	20/6090	40/18639	0.5	1.53029556650246	0.0170357306730339	0.0971248711400357
GO:0008140	cAMP response element binding protein binding	7/6090	10/18639	0.7	2.14241379310345	0.0174814258528241	0.0980386902929811
GO:0099122	RNA polymerase II C-terminal domain binding	7/6090	10/18639	0.7	2.14241379310345	0.0174814258528241	0.0980386902929811
GO:0140999	histone H3K4 trimethyltransferase activity	7/6090	10/18639	0.7	2.14241379310345	0.0174814258528241	0.0980386902929811
GO:1905394	retromer complex binding	7/6090	10/18639	0.7	2.14241379310345	0.0174814258528241	0.0980386902929811
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	15/6090	28/18639	0.535714285714286	1.63960239268121	0.0177937013084601	0.0993843316984724
GO:0009931	calcium-dependent protein serine/threonine kinase activity	12/6090	21/18639	0.571428571428571	1.74890921885996	0.0179356295429354	0.0997714777003777
GO:0004860	protein kinase inhibitor activity	37/6090	84/18639	0.44047619047619	1.34811752287122	0.0190143675365482	0.104627827319339
GO:0051117	ATPase binding	37/6090	84/18639	0.44047619047619	1.34811752287122	0.0190143675365482	0.104627827319339
GO:0008234	cysteine-type peptidase activity	75/6090	187/18639	0.401069518716578	1.22750981270251	0.0190370864845958	0.104627827319339
GO:0004843	cysteine-type deubiquitinase activity	46/6090	108/18639	0.425925925925926	1.3035851122058	0.019288691885308	0.105588297412005
GO:0051018	protein kinase A binding	25/6090	53/18639	0.471698113207547	1.44367506273817	0.0195344558673712	0.106509295086381
GO:0009378	four-way junction helicase activity	23/6090	48/18639	0.479166666666667	1.46653325123153	0.0198891181198383	0.107589166522275
GO:0043138	3'-5' DNA helicase activity	23/6090	48/18639	0.479166666666667	1.46653325123153	0.0198891181198383	0.107589166522275
GO:0004712	protein serine/threonine/tyrosine kinase activity	21/6090	43/18639	0.488372093023256	1.49470729751403	0.0200083811096332	0.107809865273083
GO:0003689	DNA clamp loader activity	65/6090	160/18639	0.40625	1.24336514778325	0.0205557731984025	0.110009423867704
GO:0042800	histone H3K4 methyltransferase activity	11/6090	19/18639	0.578947368421053	1.77192118226601	0.020602306936271	0.110009423867704
GO:0050681	nuclear androgen receptor binding	14/6090	26/18639	0.538461538461538	1.64801061007958	0.0206567913812719	0.110009423867704
GO:0019210	kinase inhibitor activity	39/6090	90/18639	0.433333333333333	1.32625615763547	0.0219171633260801	0.116270974556116
GO:0030291	protein serine/threonine kinase inhibitor activity	22/6090	46/18639	0.478260869565217	1.46376097665453	0.0230471750941011	0.121795456074211
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	10/6090	17/18639	0.588235294117647	1.80034772529702	0.0236188660294553	0.123228748381424
GO:0005092	GDP-dissociation inhibitor activity	10/6090	17/18639	0.588235294117647	1.80034772529702	0.0236188660294553	0.123228748381424
GO:0051787	misfolded protein binding	10/6090	17/18639	0.588235294117647	1.80034772529702	0.0236188660294553	0.123228748381424
GO:0016758	hexosyltransferase activity	78/6090	197/18639	0.395939086294416	1.21180765672276	0.0236771394269985	0.123228748381424
GO:0004879	nuclear receptor activity	27/6090	59/18639	0.457627118644068	1.40060950154463	0.0243647424570649	0.126328891079272
GO:0008194	UDP-glycosyltransferase activity	59/6090	145/18639	0.406896551724138	1.24534397825718	0.0254449825049231	0.130567752981428
GO:0035401	histone H3Y41 kinase activity	48/6090	115/18639	0.417391304347826	1.27746412508032	0.0254673637547473	0.130567752981428
GO:0140801	histone H2AXY142 kinase activity	48/6090	115/18639	0.417391304347826	1.27746412508032	0.0254673637547473	0.130567752981428
GO:0004559	alpha-mannosidase activity	9/6090	15/18639	0.6	1.83635467980296	0.0269931694258687	0.137365239967199
GO:0061578	K63-linked deubiquitinase activity	9/6090	15/18639	0.6	1.83635467980296	0.0269931694258687	0.137365239967199
GO:0016887	ATP hydrolysis activity	155/6090	417/18639	0.371702637889688	1.13762979763972	0.0278741702291054	0.141325128763066
GO:0030159	signaling receptor complex adaptor activity	24/6090	52/18639	0.461538461538462	1.41258052292535	0.0292228550663885	0.147618392872124
GO:0008094	ATP-dependent activity, acting on DNA	82/6090	210/18639	0.39047619047619	1.19508796622097	0.0295509367074986	0.148728890242136
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	14/6090	27/18639	0.518518518518518	1.58697318007663	0.0302330603031812	0.149995293894484
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	14/6090	27/18639	0.518518518518518	1.58697318007663	0.0302330603031812	0.149995293894484
GO:0061749	forked DNA-dependent helicase activity	22/6090	47/18639	0.468085106382979	1.43261712608741	0.0302392259161369	0.149995293894484
GO:1990518	single-stranded 3'-5' DNA helicase activity	22/6090	47/18639	0.468085106382979	1.43261712608741	0.0302392259161369	0.149995293894484
GO:0051011	microtubule minus-end binding	8/6090	13/18639	0.615384615384615	1.8834406972338	0.0306959324144442	0.150731879646075
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	8/6090	13/18639	0.615384615384615	1.8834406972338	0.0306959324144442	0.150731879646075
GO:0005496	steroid binding	45/6090	108/18639	0.416666666666667	1.27524630541872	0.0307168313689237	0.150731879646075
GO:0048487	beta-tubulin binding	20/6090	42/18639	0.476190476190476	1.45742434904996	0.0310162106791107	0.151659336203196
GO:0061608	nuclear import signal receptor activity	11/6090	20/18639	0.55	1.68332512315271	0.0324776636419672	0.158242233489585
GO:0016779	nucleotidyltransferase activity	55/6090	136/18639	0.404411764705882	1.2377390611417	0.0339712725245617	0.162861311467842
GO:0004143	ATP-dependent diacylglycerol kinase activity	7/6090	11/18639	0.636363636363636	1.94764890282132	0.0346172153918448	0.162861311467842
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	7/6090	11/18639	0.636363636363636	1.94764890282132	0.0346172153918448	0.162861311467842
GO:0019215	intermediate filament binding	7/6090	11/18639	0.636363636363636	1.94764890282132	0.0346172153918448	0.162861311467842
GO:0035252	UDP-xylosyltransferase activity	7/6090	11/18639	0.636363636363636	1.94764890282132	0.0346172153918448	0.162861311467842
GO:0042285	xylosyltransferase activity	7/6090	11/18639	0.636363636363636	1.94764890282132	0.0346172153918448	0.162861311467842
GO:0045294	alpha-catenin binding	7/6090	11/18639	0.636363636363636	1.94764890282132	0.0346172153918448	0.162861311467842
GO:0048407	platelet-derived growth factor binding	7/6090	11/18639	0.636363636363636	1.94764890282132	0.0346172153918448	0.162861311467842
GO:0097493	structural molecule activity conferring elasticity	7/6090	11/18639	0.636363636363636	1.94764890282132	0.0346172153918448	0.162861311467842
GO:0180030	inositol phosphate kinase activity	7/6090	11/18639	0.636363636363636	1.94764890282132	0.0346172153918448	0.162861311467842
GO:0140303	intramembrane lipid transporter activity	21/6090	45/18639	0.466666666666667	1.42827586206897	0.0350219471837398	0.162861311467842
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	52/6090	128/18639	0.40625	1.24336514778325	0.035243916472017	0.162861311467842
GO:0000030	mannosyltransferase activity	13/6090	25/18639	0.52	1.59150738916256	0.0353221767230109	0.162861311467842
GO:0003707	nuclear steroid receptor activity	13/6090	25/18639	0.52	1.59150738916256	0.0353221767230109	0.162861311467842
GO:0008139	nuclear localization sequence binding	13/6090	25/18639	0.52	1.59150738916256	0.0353221767230109	0.162861311467842
GO:0042974	nuclear retinoic acid receptor binding	13/6090	25/18639	0.52	1.59150738916256	0.0353221767230109	0.162861311467842
GO:0003924	GTPase activity	124/6090	331/18639	0.374622356495468	1.14656586251544	0.0358068538224805	0.164450865594654
GO:0061791	GTPase motor activity	19/6090	40/18639	0.475	1.45378078817734	0.0360259902066891	0.164450865594654
GO:1990606	membrane scission GTPase motor activity	19/6090	40/18639	0.475	1.45378078817734	0.0360259902066891	0.164450865594654
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	35/6090	82/18639	0.426829268292683	1.30634987384357	0.0364451628235842	0.165323935387032
GO:0070566	adenylyltransferase activity	15/6090	30/18639	0.5	1.53029556650246	0.036492903158642	0.165323935387032
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	177/6090	484/18639	0.365702479338843	1.11926576558238	0.0365782215121234	0.165323935387032
GO:0005200	structural constituent of cytoskeleton	46/6090	112/18639	0.410714285714286	1.25702850105559	0.0377016442007501	0.169308070334326
GO:0000900	mRNA regulatory element binding translation repressor activity	10/6090	18/18639	0.555555555555556	1.70032840722496	0.0378293868942052	0.169308070334326
GO:1990381	ubiquitin-specific protease binding	10/6090	18/18639	0.555555555555556	1.70032840722496	0.0378293868942052	0.169308070334326
GO:0019905	syntaxin binding	27/6090	61/18639	0.442622950819672	1.35468787854316	0.0384663804403541	0.171600021834566
GO:0036121	double-stranded DNA helicase activity	22/6090	48/18639	0.458333333333333	1.40277093596059	0.0389970094360817	0.17340417788083
GO:0101005	deubiquitinase activity	47/6090	115/18639	0.408695652173913	1.25085028914114	0.0392594495872705	0.174008012041644
GO:0001216	DNA-binding transcription activator activity	179/6090	491/18639	0.364562118126273	1.11577558616677	0.0398805914984755	0.176192709707091
GO:0044013	histone H2B acetyltransferase activity	12/6090	23/18639	0.521739130434783	1.5968301563504	0.0413383107004724	0.182047560584773
GO:0042162	telomeric DNA binding	18/6090	38/18639	0.473684210526316	1.44975369458128	0.0418841590491476	0.183862091161434
GO:0046875	ephrin receptor binding	14/6090	28/18639	0.5	1.53029556650246	0.0426724192979023	0.186725809284451
GO:0005048	signal sequence binding	23/6090	51/18639	0.450980392156863	1.38026658939438	0.0429220557291524	0.187221919275731
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	9/6090	16/18639	0.5625	1.72158251231527	0.0440975658983524	0.188754067116312
GO:0004708	MAP kinase kinase activity	9/6090	16/18639	0.5625	1.72158251231527	0.0440975658983524	0.188754067116312
GO:0015923	mannosidase activity	9/6090	16/18639	0.5625	1.72158251231527	0.0440975658983524	0.188754067116312
GO:0030275	LRR domain binding	9/6090	16/18639	0.5625	1.72158251231527	0.0440975658983524	0.188754067116312
GO:0031435	mitogen-activated protein kinase kinase kinase binding	9/6090	16/18639	0.5625	1.72158251231527	0.0440975658983524	0.188754067116312
GO:0140327	flippase activity	9/6090	16/18639	0.5625	1.72158251231527	0.0440975658983524	0.188754067116312
GO:0019199	transmembrane receptor protein kinase activity	33/6090	78/18639	0.423076923076923	1.29486547934824	0.0468927904803834	0.200095323354183
GO:0097110	scaffold protein binding	30/6090	70/18639	0.428571428571429	1.31168191414497	0.0474233840161856	0.201732909096715
GO:0016409	palmitoyltransferase activity	17/6090	36/18639	0.472222222222222	1.44527914614122	0.0487450715954417	0.203447458252703
GO:0001618	virus receptor activity	34/6090	81/18639	0.419753086419753	1.28469257434775	0.0494552045534227	0.203447458252703
GO:0030971	receptor tyrosine kinase binding	34/6090	81/18639	0.419753086419753	1.28469257434775	0.0494552045534227	0.203447458252703
GO:0033192	calmodulin-dependent protein phosphatase activity	34/6090	81/18639	0.419753086419753	1.28469257434775	0.0494552045534227	0.203447458252703
GO:0140791	histone H2AXS140 phosphatase activity	34/6090	81/18639	0.419753086419753	1.28469257434775	0.0494552045534227	0.203447458252703
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	34/6090	81/18639	0.419753086419753	1.28469257434775	0.0494552045534227	0.203447458252703
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	34/6090	81/18639	0.419753086419753	1.28469257434775	0.0494552045534227	0.203447458252703
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	34/6090	81/18639	0.419753086419753	1.28469257434775	0.0494552045534227	0.203447458252703
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	34/6090	81/18639	0.419753086419753	1.28469257434775	0.0494552045534227	0.203447458252703
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	34/6090	81/18639	0.419753086419753	1.28469257434775	0.0494552045534227	0.203447458252703
GO:1990439	MAP kinase serine/threonine phosphatase activity	34/6090	81/18639	0.419753086419753	1.28469257434775	0.0494552045534227	0.203447458252703
GO:0034237	protein kinase A regulatory subunit binding	13/6090	26/18639	0.5	1.53029556650246	0.0499875620647501	0.203806855421266
GO:0043548	phosphatidylinositol 3-kinase binding	13/6090	26/18639	0.5	1.53029556650246	0.0499875620647501	0.203806855421266
GO:0097602	cullin family protein binding	13/6090	26/18639	0.5	1.53029556650246	0.0499875620647501	0.203806855421266
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	87/6090	229/18639	0.379912663755459	1.16275733000624	0.0501736931883585	0.203960516097055
GO:0005161	platelet-derived growth factor receptor binding	8/6090	14/18639	0.571428571428571	1.74890921885996	0.0514354138556041	0.205442612318605
GO:0008191	metalloendopeptidase inhibitor activity	8/6090	14/18639	0.571428571428571	1.74890921885996	0.0514354138556041	0.205442612318605
GO:0042043	neurexin family protein binding	8/6090	14/18639	0.571428571428571	1.74890921885996	0.0514354138556041	0.205442612318605
GO:0042813	Wnt receptor activity	8/6090	14/18639	0.571428571428571	1.74890921885996	0.0514354138556041	0.205442612318605
GO:0061665	SUMO ligase activity	8/6090	14/18639	0.571428571428571	1.74890921885996	0.0514354138556041	0.205442612318605
GO:0098821	BMP receptor activity	8/6090	14/18639	0.571428571428571	1.74890921885996	0.0514354138556041	0.205442612318605
GO:0031490	chromatin DNA binding	51/6090	128/18639	0.3984375	1.21945427955665	0.0520343646551589	0.207053660086942
GO:0001046	core promoter sequence-specific DNA binding	20/6090	44/18639	0.454545454545455	1.39117778772951	0.0521401502111222	0.207053660086942
GO:0017022	myosin binding	32/6090	76/18639	0.421052631578947	1.28866995073892	0.0531559653286553	0.210479240235079
GO:0005080	protein kinase C binding	23/6090	52/18639	0.442307692307692	1.35372300113679	0.0537869390134132	0.211906144274299
GO:0005548	phospholipid transporter activity	29/6090	68/18639	0.426470588235294	1.30525210084034	0.0539790032722014	0.211906144274299
GO:0030145	manganese ion binding	29/6090	68/18639	0.426470588235294	1.30525210084034	0.0539790032722014	0.211906144274299
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	10/6090	19/18639	0.526315789473684	1.61083743842365	0.0569705868474654	0.223013066462728
GO:0016417	S-acyltransferase activity	14/6090	29/18639	0.482758620689655	1.47752675386445	0.0583117946492795	0.226466692835965
GO:0035250	UDP-galactosyltransferase activity	14/6090	29/18639	0.482758620689655	1.47752675386445	0.0583117946492795	0.226466692835965
GO:0033549	MAP kinase phosphatase activity	34/6090	82/18639	0.414634146341463	1.26902559173375	0.0586706507787248	0.226466692835965
GO:0140272	exogenous protein binding	34/6090	82/18639	0.414634146341463	1.26902559173375	0.0586706507787248	0.226466692835965
GO:0050431	transforming growth factor beta binding	12/6090	24/18639	0.5	1.53029556650246	0.0586769597158686	0.226466692835965
GO:0051219	phosphoprotein binding	38/6090	93/18639	0.408602150537634	1.25056411886223	0.0592683656746791	0.227755211603045
GO:0005078	MAP-kinase scaffold activity	7/6090	12/18639	0.583333333333333	1.78534482758621	0.0600053759827527	0.227755211603045
GO:0005527	macrolide binding	7/6090	12/18639	0.583333333333333	1.78534482758621	0.0600053759827527	0.227755211603045
GO:0035014	phosphatidylinositol 3-kinase regulator activity	7/6090	12/18639	0.583333333333333	1.78534482758621	0.0600053759827527	0.227755211603045
GO:0045295	gamma-catenin binding	7/6090	12/18639	0.583333333333333	1.78534482758621	0.0600053759827527	0.227755211603045
GO:1990247	N6-methyladenosine-containing RNA reader activity	7/6090	12/18639	0.583333333333333	1.78534482758621	0.0600053759827527	0.227755211603045
GO:0016407	acetyltransferase activity	39/6090	96/18639	0.40625	1.24336514778325	0.0616077400822773	0.23319293353457
GO:0015297	antiporter activity	53/6090	135/18639	0.392592592592593	1.2015654077723	0.0626644655031904	0.236541141762043
GO:0004715	non-membrane spanning protein tyrosine kinase activity	20/6090	45/18639	0.444444444444444	1.36026272577997	0.0658347126330281	0.240882612276051
GO:0008378	galactosyltransferase activity	15/6090	32/18639	0.46875	1.43465209359606	0.0662562876338111	0.240882612276051
GO:0120015	sterol transfer activity	15/6090	32/18639	0.46875	1.43465209359606	0.0662562876338111	0.240882612276051
GO:0008569	minus-end-directed microtubule motor activity	9/6090	17/18639	0.529411764705882	1.62031295276731	0.0671361032508617	0.240882612276051
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	9/6090	17/18639	0.529411764705882	1.62031295276731	0.0671361032508617	0.240882612276051
GO:0038191	neuropilin binding	9/6090	17/18639	0.529411764705882	1.62031295276731	0.0671361032508617	0.240882612276051
GO:0008093	cytoskeletal anchor activity	11/6090	22/18639	0.5	1.53029556650246	0.0690410613019544	0.240882612276051
GO:0032931	histone H3K56 acetyltransferase activity	11/6090	22/18639	0.5	1.53029556650246	0.0690410613019544	0.240882612276051
GO:0043992	histone H3K9 acetyltransferase activity	11/6090	22/18639	0.5	1.53029556650246	0.0690410613019544	0.240882612276051
GO:0043993	histone H3K18 acetyltransferase activity	11/6090	22/18639	0.5	1.53029556650246	0.0690410613019544	0.240882612276051
GO:0043994	histone H3K23 acetyltransferase activity	11/6090	22/18639	0.5	1.53029556650246	0.0690410613019544	0.240882612276051
GO:0043999	histone H2AK5 acetyltransferase activity	11/6090	22/18639	0.5	1.53029556650246	0.0690410613019544	0.240882612276051
GO:0044012	histone H2AK9 acetyltransferase activity	11/6090	22/18639	0.5	1.53029556650246	0.0690410613019544	0.240882612276051
GO:0044014	histone H2BK5 acetyltransferase activity	11/6090	22/18639	0.5	1.53029556650246	0.0690410613019544	0.240882612276051
GO:0044015	histone H2BK12 acetyltransferase activity	11/6090	22/18639	0.5	1.53029556650246	0.0690410613019544	0.240882612276051
GO:0044016	histone H3K4 acetyltransferase activity	11/6090	22/18639	0.5	1.53029556650246	0.0690410613019544	0.240882612276051
GO:0044017	histone H3K27 acetyltransferase activity	11/6090	22/18639	0.5	1.53029556650246	0.0690410613019544	0.240882612276051
GO:0044018	histone H3K36 acetyltransferase activity	11/6090	22/18639	0.5	1.53029556650246	0.0690410613019544	0.240882612276051
GO:0140908	histone H3K122 acetyltransferase activity	11/6090	22/18639	0.5	1.53029556650246	0.0690410613019544	0.240882612276051
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	34/6090	83/18639	0.409638554216867	1.2537361267731	0.0690595881702213	0.240882612276051
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	69/6090	181/18639	0.38121546961326	1.16674468606265	0.0692966416318228	0.240882612276051
GO:0071949	FAD binding	18/6090	40/18639	0.45	1.37726600985222	0.0698645446541903	0.240882612276051
GO:0004862	cAMP-dependent protein kinase inhibitor activity	6/6090	10/18639	0.6	1.83635467980296	0.0699506275823468	0.240882612276051
GO:0005131	growth hormone receptor binding	6/6090	10/18639	0.6	1.83635467980296	0.0699506275823468	0.240882612276051
GO:0005528	FK506 binding	6/6090	10/18639	0.6	1.83635467980296	0.0699506275823468	0.240882612276051
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	6/6090	10/18639	0.6	1.83635467980296	0.0699506275823468	0.240882612276051
GO:0015924	mannosyl-oligosaccharide mannosidase activity	6/6090	10/18639	0.6	1.83635467980296	0.0699506275823468	0.240882612276051
GO:0016427	tRNA (cytidine) methyltransferase activity	6/6090	10/18639	0.6	1.83635467980296	0.0699506275823468	0.240882612276051
GO:0019911	structural constituent of myelin sheath	6/6090	10/18639	0.6	1.83635467980296	0.0699506275823468	0.240882612276051
GO:0035256	G protein-coupled glutamate receptor binding	6/6090	10/18639	0.6	1.83635467980296	0.0699506275823468	0.240882612276051
GO:0042975	peroxisome proliferator activated receptor binding	6/6090	10/18639	0.6	1.83635467980296	0.0699506275823468	0.240882612276051
GO:0045322	unmethylated CpG binding	6/6090	10/18639	0.6	1.83635467980296	0.0699506275823468	0.240882612276051
GO:0050815	phosphoserine residue binding	6/6090	10/18639	0.6	1.83635467980296	0.0699506275823468	0.240882612276051
GO:0070097	delta-catenin binding	6/6090	10/18639	0.6	1.83635467980296	0.0699506275823468	0.240882612276051
GO:0070513	death domain binding	6/6090	10/18639	0.6	1.83635467980296	0.0699506275823468	0.240882612276051
GO:0019003	GDP binding	31/6090	75/18639	0.413333333333333	1.26504433497537	0.0714536543711548	0.245443302764917
GO:0004722	protein serine/threonine phosphatase activity	41/6090	103/18639	0.398058252427184	1.21829355779808	0.0761798462430896	0.261025208822955
GO:0016278	lysine N-methyltransferase activity	29/6090	70/18639	0.414285714285714	1.26795918367347	0.0771854527202086	0.263812965267579
GO:0015101	organic cation transmembrane transporter activity	33/6090	81/18639	0.407407407407407	1.24690749863164	0.0776903458856268	0.264879740066629
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	8/6090	15/18639	0.533333333333333	1.63231527093596	0.0793694074895873	0.267288151692875
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	8/6090	15/18639	0.533333333333333	1.63231527093596	0.0793694074895873	0.267288151692875
GO:0031005	filamin binding	8/6090	15/18639	0.533333333333333	1.63231527093596	0.0793694074895873	0.267288151692875
GO:0141050	histone H3K deacetylase activity	8/6090	15/18639	0.533333333333333	1.63231527093596	0.0793694074895873	0.267288151692875
GO:0141051	histone H4K deacetylase activity	8/6090	15/18639	0.533333333333333	1.63231527093596	0.0793694074895873	0.267288151692875
GO:0017025	TBP-class protein binding	12/6090	25/18639	0.48	1.46908374384236	0.0802352209400449	0.268231614529493
GO:0019706	protein-cysteine S-palmitoyltransferase activity	12/6090	25/18639	0.48	1.46908374384236	0.0802352209400449	0.268231614529493
GO:0019707	protein-cysteine S-acyltransferase activity	12/6090	25/18639	0.48	1.46908374384236	0.0802352209400449	0.268231614529493
GO:0017018	myosin phosphatase activity	34/6090	84/18639	0.404761904761905	1.23881069669247	0.0806768791205086	0.269053475513541
GO:0140463	chromatin-protein adaptor activity	23/6090	54/18639	0.425925925925926	1.3035851122058	0.0810805941549146	0.269745124379789
GO:0017124	SH3 domain binding	45/6090	115/18639	0.391304347826087	1.1976226172628	0.0849792826312292	0.282032691631181
GO:0140416	transcription regulator inhibitor activity	15/6090	33/18639	0.454545454545455	1.39117778772951	0.085899761815338	0.284400657191023
GO:0003777	microtubule motor activity	28/6090	68/18639	0.411764705882353	1.26024340770791	0.0872991195227456	0.287647458571349
GO:1990841	promoter-specific chromatin binding	28/6090	68/18639	0.411764705882353	1.26024340770791	0.0872991195227456	0.287647458571349
GO:0140318	protein transporter activity	18/6090	41/18639	0.439024390243902	1.34367415595338	0.0877012219139522	0.288281050023374
GO:0019789	SUMO transferase activity	13/6090	28/18639	0.464285714285714	1.42098874032372	0.0905684888494047	0.296288342093052
GO:0051959	dynein light intermediate chain binding	13/6090	28/18639	0.464285714285714	1.42098874032372	0.0905684888494047	0.296288342093052
GO:0005319	lipid transporter activity	67/6090	178/18639	0.376404494382022	1.15202025792882	0.0912620306072029	0.297848052385503
GO:0045505	dynein intermediate chain binding	16/6090	36/18639	0.444444444444444	1.36026272577997	0.0938455268237772	0.301702621539162
GO:0030020	extracellular matrix structural constituent conferring tensile strength	19/6090	44/18639	0.431818181818182	1.32161889834304	0.0940855279471366	0.301702621539162
GO:0004535	poly(A)-specific ribonuclease activity	7/6090	13/18639	0.538461538461538	1.64801061007958	0.0941997268124458	0.301702621539162
GO:0039706	co-receptor binding	7/6090	13/18639	0.538461538461538	1.64801061007958	0.0941997268124458	0.301702621539162
GO:0043560	insulin receptor substrate binding	7/6090	13/18639	0.538461538461538	1.64801061007958	0.0941997268124458	0.301702621539162
GO:0046975	histone H3K36 methyltransferase activity	7/6090	13/18639	0.538461538461538	1.64801061007958	0.0941997268124458	0.301702621539162
GO:0070700	BMP receptor binding	7/6090	13/18639	0.538461538461538	1.64801061007958	0.0941997268124458	0.301702621539162
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	7/6090	13/18639	0.538461538461538	1.64801061007958	0.0941997268124458	0.301702621539162
GO:0017075	syntaxin-1 binding	9/6090	18/18639	0.5	1.53029556650246	0.0964428196075182	0.30816845149007
GO:0003724	RNA helicase activity	31/6090	77/18639	0.402597402597403	1.23218604056042	0.0980869301681212	0.312694761139208
GO:0016411	acylglycerol O-acyltransferase activity	14/6090	31/18639	0.451612903225806	1.38220244716352	0.100093877298692	0.31835413751945
GO:0016776	phosphotransferase activity, phosphate group as acceptor	17/6090	39/18639	0.435897435897436	1.33410382720728	0.101274557366809	0.32111017244493
GO:0048306	calcium-dependent protein binding	32/6090	80/18639	0.4	1.22423645320197	0.101427812839228	0.32111017244493
GO:0008080	N-acetyltransferase activity	28/6090	69/18639	0.405797101449275	1.24197901049475	0.102626501655373	0.323414709345144
GO:0016279	protein-lysine N-methyltransferase activity	28/6090	69/18639	0.405797101449275	1.24197901049475	0.102626501655373	0.323414709345144
GO:0005112	Notch binding	12/6090	26/18639	0.461538461538462	1.41258052292535	0.106161785690297	0.333028067439426
GO:0050750	low-density lipoprotein particle receptor binding	12/6090	26/18639	0.461538461538462	1.41258052292535	0.106161785690297	0.333028067439426
GO:0051087	protein-folding chaperone binding	51/6090	134/18639	0.380597014925373	1.16485184912874	0.108076887064517	0.338263423295322
GO:0030332	cyclin binding	15/6090	34/18639	0.441176470588235	1.35026079397276	0.10887771565583	0.339995412070704
GO:0004864	protein phosphatase inhibitor activity	22/6090	53/18639	0.415094339622642	1.27043405520959	0.111216860229598	0.341526310437709
GO:0140296	general transcription initiation factor binding	22/6090	53/18639	0.415094339622642	1.27043405520959	0.111216860229598	0.341526310437709
GO:0005123	death receptor binding	10/6090	21/18639	0.476190476190476	1.45742434904996	0.111454063600292	0.341526310437709
GO:0019200	carbohydrate kinase activity	10/6090	21/18639	0.476190476190476	1.45742434904996	0.111454063600292	0.341526310437709
GO:0004016	adenylate cyclase activity	6/6090	11/18639	0.545454545454545	1.66941334527541	0.112350722210949	0.341526310437709
GO:0008432	JUN kinase binding	6/6090	11/18639	0.545454545454545	1.66941334527541	0.112350722210949	0.341526310437709
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	6/6090	11/18639	0.545454545454545	1.66941334527541	0.112350722210949	0.341526310437709
GO:0032794	GTPase activating protein binding	6/6090	11/18639	0.545454545454545	1.66941334527541	0.112350722210949	0.341526310437709
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	6/6090	11/18639	0.545454545454545	1.66941334527541	0.112350722210949	0.341526310437709
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	6/6090	11/18639	0.545454545454545	1.66941334527541	0.112350722210949	0.341526310437709
GO:0043522	leucine zipper domain binding	6/6090	11/18639	0.545454545454545	1.66941334527541	0.112350722210949	0.341526310437709
GO:0050998	nitric-oxide synthase binding	6/6090	11/18639	0.545454545454545	1.66941334527541	0.112350722210949	0.341526310437709
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	8/6090	16/18639	0.5	1.53029556650246	0.114641249080822	0.347719815092825
GO:0019212	phosphatase inhibitor activity	23/6090	56/18639	0.410714285714286	1.25702850105559	0.116323875222892	0.35204626554241
GO:0045309	protein phosphorylated amino acid binding	24/6090	59/18639	0.406779661016949	1.24498622359522	0.121162641145364	0.365884547107098
GO:0004622	lysophospholipase activity	11/6090	24/18639	0.458333333333333	1.40277093596059	0.124692263661919	0.37326180887032
GO:0043998	histone H2A acetyltransferase activity	11/6090	24/18639	0.458333333333333	1.40277093596059	0.124692263661919	0.37326180887032
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	11/6090	24/18639	0.458333333333333	1.40277093596059	0.124692263661919	0.37326180887032
GO:0070840	dynein complex binding	11/6090	24/18639	0.458333333333333	1.40277093596059	0.124692263661919	0.37326180887032
GO:0140097	catalytic activity, acting on DNA	120/6090	336/18639	0.357142857142857	1.09306826178747	0.127387881583215	0.380502063685515
GO:0008186	ATP-dependent activity, acting on RNA	31/6090	79/18639	0.392405063291139	1.2009914572551	0.130511400836712	0.388273655614158
GO:0008200	ion channel inhibitor activity	18/6090	43/18639	0.418604651162791	1.28117768358346	0.131444621493336	0.388273655614158
GO:0003925	G protein activity	22/6090	54/18639	0.407407407407407	1.24690749863164	0.131935543155943	0.388273655614158
GO:0005346	purine ribonucleotide transmembrane transporter activity	9/6090	19/18639	0.473684210526316	1.44975369458128	0.131967829091566	0.388273655614158
GO:0042577	lipid phosphatase activity	9/6090	19/18639	0.473684210526316	1.44975369458128	0.131967829091566	0.388273655614158
GO:0043395	heparan sulfate proteoglycan binding	9/6090	19/18639	0.473684210526316	1.44975369458128	0.131967829091566	0.388273655614158
GO:0050145	nucleoside monophosphate kinase activity	9/6090	19/18639	0.473684210526316	1.44975369458128	0.131967829091566	0.388273655614158
GO:0043015	gamma-tubulin binding	15/6090	35/18639	0.428571428571429	1.31168191414497	0.135185342355981	0.396890299993841
GO:0004683	calcium/calmodulin-dependent protein kinase activity	12/6090	27/18639	0.444444444444444	1.36026272577997	0.13642639185357	0.3987046411928
GO:0005347	ATP transmembrane transporter activity	7/6090	14/18639	0.5	1.53029556650246	0.136964039769288	0.3987046411928
GO:0008195	phosphatidate phosphatase activity	7/6090	14/18639	0.5	1.53029556650246	0.136964039769288	0.3987046411928
GO:0071933	Arp2/3 complex binding	7/6090	14/18639	0.5	1.53029556650246	0.136964039769288	0.3987046411928
GO:0005109	frizzled binding	16/6090	38/18639	0.421052631578947	1.28866995073892	0.143201247925684	0.415979946405687
GO:0016763	pentosyltransferase activity	20/6090	49/18639	0.408163265306122	1.24922087061426	0.14391704547608	0.417177258405346
GO:0004407	histone deacetylase activity	10/6090	22/18639	0.454545454545455	1.39117778772951	0.14679823218224	0.422852769430604
GO:0033558	protein lysine deacetylase activity	10/6090	22/18639	0.454545454545455	1.39117778772951	0.14679823218224	0.422852769430604
GO:0046972	histone H4K16 acetyltransferase activity	10/6090	22/18639	0.454545454545455	1.39117778772951	0.14679823218224	0.422852769430604
GO:0098632	cell-cell adhesion mediator activity	22/6090	55/18639	0.4	1.22423645320197	0.154769419817977	0.444881135627407
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	8/6090	17/18639	0.470588235294118	1.44027818023761	0.156868045374121	0.447171565029132
GO:0015278	intracellularly gated calcium channel activity	8/6090	17/18639	0.470588235294118	1.44027818023761	0.156868045374121	0.447171565029132
GO:0046965	nuclear retinoid X receptor binding	8/6090	17/18639	0.470588235294118	1.44027818023761	0.156868045374121	0.447171565029132
GO:1990226	histone methyltransferase binding	8/6090	17/18639	0.470588235294118	1.44027818023761	0.156868045374121	0.447171565029132
GO:0016248	channel inhibitor activity	18/6090	44/18639	0.409090909090909	1.25206000895656	0.157308609333012	0.447499025307576
GO:0016874	ligase activity	61/6090	167/18639	0.365269461077844	1.11794047373234	0.162533401113664	0.452633472996019
GO:0015291	secondary active transmembrane transporter activity	102/6090	287/18639	0.355400696864112	1.08773622148607	0.163437580651322	0.452633472996019
GO:0000995	RNA polymerase III general transcription initiation factor activity	6/6090	12/18639	0.5	1.53029556650246	0.164696068439146	0.452633472996019
GO:0005247	voltage-gated chloride channel activity	6/6090	12/18639	0.5	1.53029556650246	0.164696068439146	0.452633472996019
GO:0008603	cAMP-dependent protein kinase regulator activity	6/6090	12/18639	0.5	1.53029556650246	0.164696068439146	0.452633472996019
GO:0017166	vinculin binding	6/6090	12/18639	0.5	1.53029556650246	0.164696068439146	0.452633472996019
GO:0035197	siRNA binding	6/6090	12/18639	0.5	1.53029556650246	0.164696068439146	0.452633472996019
GO:0035251	UDP-glucosyltransferase activity	6/6090	12/18639	0.5	1.53029556650246	0.164696068439146	0.452633472996019
GO:0035259	nuclear glucocorticoid receptor binding	6/6090	12/18639	0.5	1.53029556650246	0.164696068439146	0.452633472996019
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	6/6090	12/18639	0.5	1.53029556650246	0.164696068439146	0.452633472996019
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	6/6090	12/18639	0.5	1.53029556650246	0.164696068439146	0.452633472996019
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	6/6090	12/18639	0.5	1.53029556650246	0.164696068439146	0.452633472996019
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	6/6090	12/18639	0.5	1.53029556650246	0.164696068439146	0.452633472996019
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	6/6090	12/18639	0.5	1.53029556650246	0.164696068439146	0.452633472996019
GO:0141221	histone deacetylase activity, hydrolytic mechanism	6/6090	12/18639	0.5	1.53029556650246	0.164696068439146	0.452633472996019
GO:1990817	poly(A) RNA polymerase activity	6/6090	12/18639	0.5	1.53029556650246	0.164696068439146	0.452633472996019
GO:0005484	SNAP receptor activity	15/6090	36/18639	0.416666666666667	1.27524630541872	0.164713782021841	0.452633472996019
GO:0042826	histone deacetylase binding	47/6090	127/18639	0.37007874015748	1.13265971063962	0.170736924608104	0.467542692136649
GO:0046966	nuclear thyroid hormone receptor binding	12/6090	28/18639	0.428571428571429	1.31168191414497	0.170819819106694	0.467542692136649
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	16/6090	39/18639	0.41025641025641	1.2556271314892	0.172367641357946	0.469624919871129
GO:0042054	histone methyltransferase activity	26/6090	67/18639	0.388059701492537	1.1876920814646	0.172697225593336	0.469624919871129
GO:0001972	retinoic acid binding	9/6090	20/18639	0.45	1.37726600985222	0.173289544668604	0.469624919871129
GO:0030742	GTP-dependent protein binding	9/6090	20/18639	0.45	1.37726600985222	0.173289544668604	0.469624919871129
GO:0052745	inositol phosphate phosphatase activity	9/6090	20/18639	0.45	1.37726600985222	0.173289544668604	0.469624919871129
GO:0051879	Hsp90 protein binding	17/6090	42/18639	0.404761904761905	1.23881069669247	0.179331511864105	0.485042317522204
GO:0017147	Wnt-protein binding	13/6090	31/18639	0.419354838709677	1.28347370093755	0.180680955707057	0.486775751257836
GO:0070325	lipoprotein particle receptor binding	13/6090	31/18639	0.419354838709677	1.28347370093755	0.180680955707057	0.486775751257836
GO:0098631	cell adhesion mediator activity	29/6090	76/18639	0.381578947368421	1.16785714285714	0.183610965738098	0.493701500830032
GO:0141110	transporter inhibitor activity	18/6090	45/18639	0.4	1.22423645320197	0.1856941125398	0.494110820155991
GO:0000295	adenine nucleotide transmembrane transporter activity	10/6090	23/18639	0.434782608695652	1.33069179695866	0.187077449742954	0.494110820155991
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	10/6090	23/18639	0.434782608695652	1.33069179695866	0.187077449742954	0.494110820155991
GO:0016849	phosphorus-oxygen lyase activity	10/6090	23/18639	0.434782608695652	1.33069179695866	0.187077449742954	0.494110820155991
GO:0043274	phospholipase binding	10/6090	23/18639	0.434782608695652	1.33069179695866	0.187077449742954	0.494110820155991
GO:0140103	catalytic activity, acting on a glycoprotein	10/6090	23/18639	0.434782608695652	1.33069179695866	0.187077449742954	0.494110820155991
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	10/6090	23/18639	0.434782608695652	1.33069179695866	0.187077449742954	0.494110820155991
GO:0005523	tropomyosin binding	7/6090	15/18639	0.466666666666667	1.42827586206897	0.187359343014026	0.494110820155991
GO:0015929	hexosaminidase activity	7/6090	15/18639	0.466666666666667	1.42827586206897	0.187359343014026	0.494110820155991
GO:0045504	dynein heavy chain binding	7/6090	15/18639	0.466666666666667	1.42827586206897	0.187359343014026	0.494110820155991
GO:0016879	ligase activity, forming carbon-nitrogen bonds	19/6090	48/18639	0.395833333333333	1.21148399014778	0.191529607603393	0.503177210032624
GO:0140693	molecular condensate scaffold activity	19/6090	48/18639	0.395833333333333	1.21148399014778	0.191529607603393	0.503177210032624
GO:0005010	insulin-like growth factor receptor activity	20/6090	51/18639	0.392156862745098	1.20023181686468	0.196900402825367	0.504533133585842
GO:0005160	transforming growth factor beta receptor binding	11/6090	26/18639	0.423076923076923	1.29486547934824	0.198827539024233	0.504533133585842
GO:0005227	calcium-activated cation channel activity	11/6090	26/18639	0.423076923076923	1.29486547934824	0.198827539024233	0.504533133585842
GO:0008157	protein phosphatase 1 binding	11/6090	26/18639	0.423076923076923	1.29486547934824	0.198827539024233	0.504533133585842
GO:0030507	spectrin binding	11/6090	26/18639	0.423076923076923	1.29486547934824	0.198827539024233	0.504533133585842
GO:0051139	metal cation:proton antiporter activity	11/6090	26/18639	0.423076923076923	1.29486547934824	0.198827539024233	0.504533133585842
GO:0120014	phospholipid transfer activity	11/6090	26/18639	0.423076923076923	1.29486547934824	0.198827539024233	0.504533133585842
GO:0000182	rDNA binding	5/6090	10/18639	0.5	1.53029556650246	0.199756932074744	0.504533133585842
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	5/6090	10/18639	0.5	1.53029556650246	0.199756932074744	0.504533133585842
GO:0003680	minor groove of adenine-thymine-rich DNA binding	5/6090	10/18639	0.5	1.53029556650246	0.199756932074744	0.504533133585842
GO:0005381	iron ion transmembrane transporter activity	5/6090	10/18639	0.5	1.53029556650246	0.199756932074744	0.504533133585842
GO:0005522	profilin binding	5/6090	10/18639	0.5	1.53029556650246	0.199756932074744	0.504533133585842
GO:0008190	eukaryotic initiation factor 4E binding	5/6090	10/18639	0.5	1.53029556650246	0.199756932074744	0.504533133585842
GO:0008239	dipeptidyl-peptidase activity	5/6090	10/18639	0.5	1.53029556650246	0.199756932074744	0.504533133585842
GO:0030957	Tat protein binding	5/6090	10/18639	0.5	1.53029556650246	0.199756932074744	0.504533133585842
GO:0031419	cobalamin binding	5/6090	10/18639	0.5	1.53029556650246	0.199756932074744	0.504533133585842
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	5/6090	10/18639	0.5	1.53029556650246	0.199756932074744	0.504533133585842
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	5/6090	10/18639	0.5	1.53029556650246	0.199756932074744	0.504533133585842
GO:0043422	protein kinase B binding	5/6090	10/18639	0.5	1.53029556650246	0.199756932074744	0.504533133585842
GO:0070739	protein-glutamic acid ligase activity	5/6090	10/18639	0.5	1.53029556650246	0.199756932074744	0.504533133585842
GO:0070740	tubulin-glutamic acid ligase activity	5/6090	10/18639	0.5	1.53029556650246	0.199756932074744	0.504533133585842
GO:0003684	damaged DNA binding	28/6090	74/18639	0.378378378378378	1.15806150978565	0.203453941398769	0.512927918315428
GO:0003785	actin monomer binding	12/6090	29/18639	0.413793103448276	1.26645150331238	0.208967654085297	0.52586365698388
GO:0008375	acetylglucosaminyltransferase activity	17/6090	43/18639	0.395348837209302	1.2100011456066	0.210642170952684	0.529108487914055
GO:0015085	calcium ion transmembrane transporter activity	53/6090	147/18639	0.360544217687075	1.10347843570926	0.213923409529257	0.536370008564231
GO:0140098	catalytic activity, acting on RNA	134/6090	387/18639	0.34625322997416	1.05973956543323	0.219179995905364	0.548548842211239
GO:0035254	glutamate receptor binding	19/6090	49/18639	0.387755102040816	1.18675982708354	0.221684230284025	0.548622306347874
GO:0002161	aminoacyl-tRNA editing activity	6/6090	13/18639	0.461538461538462	1.41258052292535	0.225121504119174	0.548622306347874
GO:0005338	nucleotide-sugar transmembrane transporter activity	6/6090	13/18639	0.461538461538462	1.41258052292535	0.225121504119174	0.548622306347874
GO:0017154	semaphorin receptor activity	6/6090	13/18639	0.461538461538462	1.41258052292535	0.225121504119174	0.548622306347874
GO:0019855	calcium channel inhibitor activity	6/6090	13/18639	0.461538461538462	1.41258052292535	0.225121504119174	0.548622306347874
GO:0031432	titin binding	6/6090	13/18639	0.461538461538462	1.41258052292535	0.225121504119174	0.548622306347874
GO:0035673	oligopeptide transmembrane transporter activity	6/6090	13/18639	0.461538461538462	1.41258052292535	0.225121504119174	0.548622306347874
GO:0045159	myosin II binding	6/6090	13/18639	0.461538461538462	1.41258052292535	0.225121504119174	0.548622306347874
GO:0046974	histone H3K9 methyltransferase activity	6/6090	13/18639	0.461538461538462	1.41258052292535	0.225121504119174	0.548622306347874
GO:0140333	glycerophospholipid flippase activity	6/6090	13/18639	0.461538461538462	1.41258052292535	0.225121504119174	0.548622306347874
GO:0140410	monoatomic cation:bicarbonate symporter activity	6/6090	13/18639	0.461538461538462	1.41258052292535	0.225121504119174	0.548622306347874
GO:0140666	annealing activity	6/6090	13/18639	0.461538461538462	1.41258052292535	0.225121504119174	0.548622306347874
GO:0140852	histone ubiquitin ligase activity	6/6090	13/18639	0.461538461538462	1.41258052292535	0.225121504119174	0.548622306347874
GO:0000175	3'-5'-RNA exonuclease activity	14/6090	35/18639	0.4	1.22423645320197	0.225597964400691	0.548622306347874
GO:0005154	epidermal growth factor receptor binding	14/6090	35/18639	0.4	1.22423645320197	0.225597964400691	0.548622306347874
GO:0061631	ubiquitin conjugating enzyme activity	14/6090	35/18639	0.4	1.22423645320197	0.225597964400691	0.548622306347874
GO:0030552	cAMP binding	10/6090	24/18639	0.416666666666667	1.27524630541872	0.231638296943693	0.561445917893615
GO:0005501	retinoid binding	15/6090	38/18639	0.394736842105263	1.20812807881773	0.232505623931198	0.561445917893615
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	15/6090	38/18639	0.394736842105263	1.20812807881773	0.232505623931198	0.561445917893615
GO:0019840	isoprenoid binding	15/6090	38/18639	0.394736842105263	1.20812807881773	0.232505623931198	0.561445917893615
GO:0017116	single-stranded DNA helicase activity	22/6090	58/18639	0.379310344827586	1.16091387803635	0.235034044233383	0.566555748730997
GO:0140828	metal cation:monoatomic cation antiporter activity	16/6090	41/18639	0.390243902439024	1.19437702751412	0.238676544179156	0.573660398080804
GO:0015026	coreceptor activity	23/6090	61/18639	0.377049180327869	1.15399337801825	0.238816410263624	0.573660398080804
GO:0005262	calcium channel activity	47/6090	131/18639	0.358778625954198	1.09807468130711	0.243009539588616	0.580556746784249
GO:0004707	MAP kinase activity	7/6090	16/18639	0.4375	1.33900862068966	0.243917860517628	0.580556746784249
GO:0005149	interleukin-1 receptor binding	7/6090	16/18639	0.4375	1.33900862068966	0.243917860517628	0.580556746784249
GO:0005324	long-chain fatty acid transmembrane transporter activity	7/6090	16/18639	0.4375	1.33900862068966	0.243917860517628	0.580556746784249
GO:0015385	sodium:proton antiporter activity	7/6090	16/18639	0.4375	1.33900862068966	0.243917860517628	0.580556746784249
GO:0019205	nucleobase-containing compound kinase activity	17/6090	44/18639	0.386363636363636	1.18250111957008	0.244222561602108	0.580556746784249
GO:0016500	protein-hormone receptor activity	25/6090	67/18639	0.373134328358209	1.14201161679288	0.245584408595618	0.582785798636234
GO:0140359	ABC-type transporter activity	18/6090	47/18639	0.382978723404255	1.17214128498061	0.24923347270711	0.590425502585463
GO:0033612	receptor serine/threonine kinase binding	12/6090	30/18639	0.4	1.22423645320197	0.250355173849473	0.592061977399615
GO:0005525	GTP binding	130/6090	378/18639	0.343915343915344	1.05258425209164	0.252224687698556	0.59545828332958
GO:0015605	organophosphate ester transmembrane transporter activity	19/6090	50/18639	0.38	1.16302463054187	0.253782271800627	0.598107789801135
GO:0140311	protein sequestering activity	13/6090	33/18639	0.393939393939394	1.20568741603224	0.25781933592562	0.599014940942688
GO:0005544	calcium-dependent phospholipid binding	20/6090	53/18639	0.377358490566038	1.15494005019054	0.257928954798219	0.599014940942688
GO:1901505	carbohydrate derivative transmembrane transporter activity	20/6090	53/18639	0.377358490566038	1.15494005019054	0.257928954798219	0.599014940942688
GO:0003756	protein disulfide isomerase activity	8/6090	19/18639	0.421052631578947	1.28866995073892	0.258473969184373	0.599014940942688
GO:0008574	plus-end-directed microtubule motor activity	8/6090	19/18639	0.421052631578947	1.28866995073892	0.258473969184373	0.599014940942688
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	8/6090	19/18639	0.421052631578947	1.28866995073892	0.258473969184373	0.599014940942688
GO:0016918	retinal binding	8/6090	19/18639	0.421052631578947	1.28866995073892	0.258473969184373	0.599014940942688
GO:0046527	glucosyltransferase activity	8/6090	19/18639	0.421052631578947	1.28866995073892	0.258473969184373	0.599014940942688
GO:0046624	sphingolipid transporter activity	8/6090	19/18639	0.421052631578947	1.28866995073892	0.258473969184373	0.599014940942688
GO:0030246	carbohydrate binding	97/6090	280/18639	0.346428571428571	1.06027621393385	0.258526826767841	0.599014940942688
GO:0070888	E-box binding	22/6090	59/18639	0.372881355932203	1.14123737162896	0.265207112214541	0.613458875728584
GO:0000217	DNA secondary structure binding	15/6090	39/18639	0.384615384615385	1.17715043577113	0.270091863039481	0.617044703401551
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	5/6090	11/18639	0.454545454545455	1.39117778772951	0.272595440294572	0.617044703401551
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	5/6090	11/18639	0.454545454545455	1.39117778772951	0.272595440294572	0.617044703401551
GO:0005536	D-glucose binding	5/6090	11/18639	0.454545454545455	1.39117778772951	0.272595440294572	0.617044703401551
GO:0008526	phosphatidylinositol transfer activity	5/6090	11/18639	0.454545454545455	1.39117778772951	0.272595440294572	0.617044703401551
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	5/6090	11/18639	0.454545454545455	1.39117778772951	0.272595440294572	0.617044703401551
GO:0015173	aromatic amino acid transmembrane transporter activity	5/6090	11/18639	0.454545454545455	1.39117778772951	0.272595440294572	0.617044703401551
GO:0019107	myristoyltransferase activity	5/6090	11/18639	0.454545454545455	1.39117778772951	0.272595440294572	0.617044703401551
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	5/6090	11/18639	0.454545454545455	1.39117778772951	0.272595440294572	0.617044703401551
GO:0034056	estrogen response element binding	5/6090	11/18639	0.454545454545455	1.39117778772951	0.272595440294572	0.617044703401551
GO:0034713	type I transforming growth factor beta receptor binding	5/6090	11/18639	0.454545454545455	1.39117778772951	0.272595440294572	0.617044703401551
GO:0047676	arachidonate-CoA ligase activity	5/6090	11/18639	0.454545454545455	1.39117778772951	0.272595440294572	0.617044703401551
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	5/6090	11/18639	0.454545454545455	1.39117778772951	0.272595440294572	0.617044703401551
GO:0008307	structural constituent of muscle	16/6090	42/18639	0.380952380952381	1.16593947923997	0.275196564065342	0.621908024713453
GO:0043022	ribosome binding	40/6090	112/18639	0.357142857142857	1.09306826178747	0.276093893766507	0.622911346527391
GO:0120020	cholesterol transfer activity	10/6090	25/18639	0.4	1.22423645320197	0.279648630086751	0.629897078260977
GO:0070851	growth factor receptor binding	49/6090	139/18639	0.352517985611511	1.07891342098735	0.28546393698531	0.641943452402316
GO:0005030	neurotrophin receptor activity	19/6090	51/18639	0.372549019607843	1.14022022602144	0.287555881504688	0.644659963290676
GO:0097718	disordered domain specific binding	11/6090	28/18639	0.392857142857143	1.20237508796622	0.287610303855301	0.644659963290676
GO:0004705	JUN kinase activity	6/6090	14/18639	0.428571428571429	1.31168191414497	0.291239602381589	0.645424538181135
GO:0019992	diacylglycerol binding	6/6090	14/18639	0.428571428571429	1.31168191414497	0.291239602381589	0.645424538181135
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	6/6090	14/18639	0.428571428571429	1.31168191414497	0.291239602381589	0.645424538181135
GO:0044548	S100 protein binding	6/6090	14/18639	0.428571428571429	1.31168191414497	0.291239602381589	0.645424538181135
GO:0046030	inositol trisphosphate phosphatase activity	6/6090	14/18639	0.428571428571429	1.31168191414497	0.291239602381589	0.645424538181135
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	6/6090	14/18639	0.428571428571429	1.31168191414497	0.291239602381589	0.645424538181135
GO:0070742	C2H2 zinc finger domain binding	6/6090	14/18639	0.428571428571429	1.31168191414497	0.291239602381589	0.645424538181135
GO:0008170	N-methyltransferase activity	35/6090	98/18639	0.357142857142857	1.09306826178747	0.293198526243653	0.647676487232763
GO:0042626	ATPase-coupled transmembrane transporter activity	35/6090	98/18639	0.357142857142857	1.09306826178747	0.293198526243653	0.647676487232763
GO:0015932	nucleobase-containing compound transmembrane transporter activity	21/6090	57/18639	0.368421052631579	1.12758620689655	0.293965225640994	0.648157951859525
GO:0005452	solute:inorganic anion antiporter activity	12/6090	31/18639	0.387096774193548	1.18474495471158	0.294359943202579	0.648157951859525
GO:0031072	heat shock protein binding	46/6090	131/18639	0.351145038167939	1.07471139021547	0.304307491564409	0.664525957329921
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	7/6090	17/18639	0.411764705882353	1.26024340770791	0.304852731118083	0.664525957329921
GO:0019198	transmembrane receptor protein phosphatase activity	7/6090	17/18639	0.411764705882353	1.26024340770791	0.304852731118083	0.664525957329921
GO:0031489	myosin V binding	7/6090	17/18639	0.411764705882353	1.26024340770791	0.304852731118083	0.664525957329921
GO:0032183	SUMO binding	7/6090	17/18639	0.411764705882353	1.26024340770791	0.304852731118083	0.664525957329921
GO:0070402	NADPH binding	7/6090	17/18639	0.411764705882353	1.26024340770791	0.304852731118083	0.664525957329921
GO:0019213	deacetylase activity	14/6090	37/18639	0.378378378378378	1.15806150978565	0.30517895129198	0.664525957329921
GO:0004532	RNA exonuclease activity	15/6090	40/18639	0.375	1.14772167487685	0.309575600993069	0.673033031272907
GO:0000339	RNA cap binding	8/6090	20/18639	0.4	1.22423645320197	0.31526358552822	0.683699425740131
GO:0005004	GPI-linked ephrin receptor activity	18/6090	49/18639	0.36734693877551	1.12429878355283	0.319955408115651	0.683699425740131
GO:0005008	hepatocyte growth factor receptor activity	18/6090	49/18639	0.36734693877551	1.12429878355283	0.319955408115651	0.683699425740131
GO:0005009	insulin receptor activity	18/6090	49/18639	0.36734693877551	1.12429878355283	0.319955408115651	0.683699425740131
GO:0005011	macrophage colony-stimulating factor receptor activity	18/6090	49/18639	0.36734693877551	1.12429878355283	0.319955408115651	0.683699425740131
GO:0005018	platelet-derived growth factor alpha-receptor activity	18/6090	49/18639	0.36734693877551	1.12429878355283	0.319955408115651	0.683699425740131
GO:0005020	stem cell factor receptor activity	18/6090	49/18639	0.36734693877551	1.12429878355283	0.319955408115651	0.683699425740131
GO:0008288	boss receptor activity	18/6090	49/18639	0.36734693877551	1.12429878355283	0.319955408115651	0.683699425740131
GO:0036332	placental growth factor receptor activity	18/6090	49/18639	0.36734693877551	1.12429878355283	0.319955408115651	0.683699425740131
GO:0038062	protein tyrosine kinase collagen receptor activity	18/6090	49/18639	0.36734693877551	1.12429878355283	0.319955408115651	0.683699425740131
GO:0060175	brain-derived neurotrophic factor receptor activity	18/6090	49/18639	0.36734693877551	1.12429878355283	0.319955408115651	0.683699425740131
GO:0017134	fibroblast growth factor binding	9/6090	23/18639	0.391304347826087	1.1976226172628	0.323493291132357	0.690185996919035
GO:0008374	O-acyltransferase activity	20/6090	55/18639	0.363636363636364	1.11294223018361	0.325177795789398	0.692704327774624
GO:0015216	purine nucleotide transmembrane transporter activity	10/6090	26/18639	0.384615384615385	1.17715043577113	0.330161812000825	0.702232708497111
GO:0043021	ribonucleoprotein complex binding	61/6090	177/18639	0.344632768361582	1.0547799949904	0.331090124758093	0.703118750259072
GO:0022804	active transmembrane transporter activity	154/6090	457/18639	0.336980306345733	1.03135893759903	0.334746461773882	0.709786479131658
GO:0099604	ligand-gated calcium channel activity	11/6090	29/18639	0.379310344827586	1.16091387803635	0.335669700936971	0.710647409995991
GO:0022884	macromolecule transmembrane transporter activity	12/6090	32/18639	0.375	1.14772167487685	0.340288502316473	0.718212599359191
GO:0070717	poly-purine tract binding	12/6090	32/18639	0.375	1.14772167487685	0.340288502316473	0.718212599359191
GO:0016410	N-acyltransferase activity	33/6090	94/18639	0.351063829787234	1.07446284456556	0.342977185676403	0.722777075336468
GO:0000146	microfilament motor activity	14/6090	38/18639	0.368421052631579	1.12758620689655	0.347571725585768	0.724731960274516
GO:0000340	RNA 7-methylguanosine cap binding	5/6090	12/18639	0.416666666666667	1.27524630541872	0.349666420191305	0.724731960274516
GO:0004300	enoyl-CoA hydratase activity	5/6090	12/18639	0.416666666666667	1.27524630541872	0.349666420191305	0.724731960274516
GO:0005095	GTPase inhibitor activity	5/6090	12/18639	0.416666666666667	1.27524630541872	0.349666420191305	0.724731960274516
GO:0016208	AMP binding	5/6090	12/18639	0.416666666666667	1.27524630541872	0.349666420191305	0.724731960274516
GO:0043047	single-stranded telomeric DNA binding	5/6090	12/18639	0.416666666666667	1.27524630541872	0.349666420191305	0.724731960274516
GO:0070410	co-SMAD binding	5/6090	12/18639	0.416666666666667	1.27524630541872	0.349666420191305	0.724731960274516
GO:0070679	inositol 1,4,5 trisphosphate binding	5/6090	12/18639	0.416666666666667	1.27524630541872	0.349666420191305	0.724731960274516
GO:0140829	bicarbonate:monoatomic anion antiporter activity	5/6090	12/18639	0.416666666666667	1.27524630541872	0.349666420191305	0.724731960274516
GO:0140900	chloride:bicarbonate antiporter activity	5/6090	12/18639	0.416666666666667	1.27524630541872	0.349666420191305	0.724731960274516
GO:0017080	sodium channel regulator activity	15/6090	41/18639	0.365853658536585	1.11972846329449	0.350478903001096	0.724731960274516
GO:0061650	ubiquitin-like protein conjugating enzyme activity	15/6090	41/18639	0.365853658536585	1.11972846329449	0.350478903001096	0.724731960274516
GO:0004857	enzyme inhibitor activity	140/6090	416/18639	0.336538461538462	1.03000663129973	0.350761829390504	0.724731960274516
GO:0005006	epidermal growth factor receptor activity	18/6090	50/18639	0.36	1.10181280788177	0.357177797292851	0.731635939812395
GO:0005007	fibroblast growth factor receptor activity	18/6090	50/18639	0.36	1.10181280788177	0.357177797292851	0.731635939812395
GO:0005017	platelet-derived growth factor receptor activity	18/6090	50/18639	0.36	1.10181280788177	0.357177797292851	0.731635939812395
GO:0005019	platelet-derived growth factor beta-receptor activity	18/6090	50/18639	0.36	1.10181280788177	0.357177797292851	0.731635939812395
GO:0005003	ephrin receptor activity	19/6090	53/18639	0.358490566037736	1.09719304768101	0.358901721356856	0.731635939812395
GO:0005005	transmembrane-ephrin receptor activity	19/6090	53/18639	0.358490566037736	1.09719304768101	0.358901721356856	0.731635939812395
GO:0038064	collagen receptor activity	19/6090	53/18639	0.358490566037736	1.09719304768101	0.358901721356856	0.731635939812395
GO:0005041	low-density lipoprotein particle receptor activity	6/6090	15/18639	0.4	1.22423645320197	0.360493108626632	0.731635939812395
GO:0008252	nucleotidase activity	6/6090	15/18639	0.4	1.22423645320197	0.360493108626632	0.731635939812395
GO:0017081	chloride channel regulator activity	6/6090	15/18639	0.4	1.22423645320197	0.360493108626632	0.731635939812395
GO:0033130	acetylcholine receptor binding	6/6090	15/18639	0.4	1.22423645320197	0.360493108626632	0.731635939812395
GO:0050700	CARD domain binding	6/6090	15/18639	0.4	1.22423645320197	0.360493108626632	0.731635939812395
GO:0003678	DNA helicase activity	26/6090	74/18639	0.351351351351351	1.07534283051524	0.366686566249783	0.741925490331328
GO:0048029	monosaccharide binding	26/6090	74/18639	0.351351351351351	1.07534283051524	0.366686566249783	0.741925490331328
GO:0015172	acidic amino acid transmembrane transporter activity	7/6090	18/18639	0.388888888888889	1.19022988505747	0.3682628707467	0.741925490331328
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	7/6090	18/18639	0.388888888888889	1.19022988505747	0.3682628707467	0.741925490331328
GO:0017128	phospholipid scramblase activity	7/6090	18/18639	0.388888888888889	1.19022988505747	0.3682628707467	0.741925490331328
GO:0008276	protein methyltransferase activity	33/6090	95/18639	0.347368421052632	1.06315270935961	0.370219068929433	0.744774525196253
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	8/6090	21/18639	0.380952380952381	1.16593947923997	0.374092773256454	0.74927619599762
GO:0009975	cyclase activity	8/6090	21/18639	0.380952380952381	1.16593947923997	0.374092773256454	0.74927619599762
GO:0035613	RNA stem-loop binding	8/6090	21/18639	0.380952380952381	1.16593947923997	0.374092773256454	0.74927619599762
GO:0050699	WW domain binding	9/6090	24/18639	0.375	1.14772167487685	0.378606287645555	0.756044906975099
GO:0019001	guanyl nucleotide binding	134/6090	400/18639	0.335	1.02529802955665	0.379122955535548	0.756044906975099
GO:0032561	guanyl ribonucleotide binding	134/6090	400/18639	0.335	1.02529802955665	0.379122955535548	0.756044906975099
GO:0008266	poly(U) RNA binding	10/6090	27/18639	0.37037037037037	1.13355227148331	0.382181508645979	0.759938339912555
GO:0008320	protein transmembrane transporter activity	10/6090	27/18639	0.37037037037037	1.13355227148331	0.382181508645979	0.759938339912555
GO:0001965	G-protein alpha-subunit binding	11/6090	30/18639	0.366666666666667	1.12221674876847	0.385062321882364	0.760166135440184
GO:0015215	nucleotide transmembrane transporter activity	11/6090	30/18639	0.366666666666667	1.12221674876847	0.385062321882364	0.760166135440184
GO:0022839	monoatomic ion-gated channel activity	11/6090	30/18639	0.366666666666667	1.12221674876847	0.385062321882364	0.760166135440184
GO:0031210	phosphatidylcholine binding	11/6090	30/18639	0.366666666666667	1.12221674876847	0.385062321882364	0.760166135440184
GO:0051721	protein phosphatase 2A binding	11/6090	30/18639	0.366666666666667	1.12221674876847	0.385062321882364	0.760166135440184
GO:0035198	miRNA binding	15/6090	42/18639	0.357142857142857	1.09306826178747	0.39230242463207	0.773347964769676
GO:0019955	cytokine binding	49/6090	144/18639	0.340277777777778	1.04145114942529	0.394343208356755	0.773746916528758
GO:0005021	vascular endothelial growth factor receptor activity	18/6090	51/18639	0.352941176470588	1.08020863517821	0.395153387722759	0.773746916528758
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	19/6090	54/18639	0.351851851851852	1.07687465790914	0.395810929971859	0.773746916528758
GO:0016504	peptidase activator activity	20/6090	57/18639	0.350877192982456	1.07389162561576	0.396357333353897	0.773746916528758
GO:0004714	transmembrane receptor protein tyrosine kinase activity	21/6090	60/18639	0.35	1.07120689655172	0.396807975491555	0.773746916528758
GO:0005507	copper ion binding	22/6090	63/18639	0.349206349206349	1.06877785596997	0.397175565273479	0.773746916528758
GO:1901682	sulfur compound transmembrane transporter activity	22/6090	63/18639	0.349206349206349	1.06877785596997	0.397175565273479	0.773746916528758
GO:0003725	double-stranded RNA binding	26/6090	75/18639	0.346666666666667	1.06100492610837	0.398003912438336	0.773746916528758
GO:0008081	phosphoric diester hydrolase activity	30/6090	87/18639	0.344827586206897	1.05537625276032	0.398112150510886	0.773746916528758
GO:0004527	exonuclease activity	29/6090	84/18639	0.345238095238095	1.05663265306122	0.398136149916908	0.773746916528758
GO:0099106	ion channel regulator activity	54/6090	160/18639	0.3375	1.03294950738916	0.414468864439265	0.797812083762235
GO:0005539	glycosaminoglycan binding	81/6090	242/18639	0.334710743801653	1.02441273460082	0.41889579658826	0.797812083762235
GO:0016298	lipase activity	44/6090	130/18639	0.338461538461538	1.03589238347859	0.41978043037474	0.797812083762235
GO:0004382	GDP phosphatase activity	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0004445	inositol-polyphosphate 5-phosphatase activity	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0015203	polyamine transmembrane transporter activity	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0015279	store-operated calcium channel activity	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0015643	toxic substance binding	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0031957	very long-chain fatty acid-CoA ligase activity	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0035374	chondroitin sulfate binding	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0043121	neurotrophin binding	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0043295	glutathione binding	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0098505	G-rich strand telomeric DNA binding	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	4/6090	10/18639	0.4	1.22423645320197	0.422712661556701	0.797812083762235
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	5/6090	13/18639	0.384615384615385	1.17715043577113	0.427506992736388	0.800594497244888
GO:0005172	vascular endothelial growth factor receptor binding	5/6090	13/18639	0.384615384615385	1.17715043577113	0.427506992736388	0.800594497244888
GO:0008253	5'-nucleotidase activity	5/6090	13/18639	0.384615384615385	1.17715043577113	0.427506992736388	0.800594497244888
GO:0030955	potassium ion binding	5/6090	13/18639	0.384615384615385	1.17715043577113	0.427506992736388	0.800594497244888
GO:0008142	oxysterol binding	6/6090	16/18639	0.375	1.14772167487685	0.430438257492035	0.800594497244888
GO:0015562	efflux transmembrane transporter activity	6/6090	16/18639	0.375	1.14772167487685	0.430438257492035	0.800594497244888
GO:0140328	floppase activity	6/6090	16/18639	0.375	1.14772167487685	0.430438257492035	0.800594497244888
GO:0005229	intracellularly calcium-gated chloride channel activity	7/6090	19/18639	0.368421052631579	1.12758620689655	0.432306396658057	0.800594497244888
GO:0015245	fatty acid transmembrane transporter activity	7/6090	19/18639	0.368421052631579	1.12758620689655	0.432306396658057	0.800594497244888
GO:0097001	ceramide binding	7/6090	19/18639	0.368421052631579	1.12758620689655	0.432306396658057	0.800594497244888
GO:0141147	intracellularly calcium-gated channel activity	7/6090	19/18639	0.368421052631579	1.12758620689655	0.432306396658057	0.800594497244888
GO:0008408	3'-5' exonuclease activity	20/6090	58/18639	0.344827586206897	1.05537625276032	0.432644007263108	0.800594497244888
GO:0061980	regulatory RNA binding	20/6090	58/18639	0.344827586206897	1.05537625276032	0.432644007263108	0.800594497244888
GO:0140313	molecular sequestering activity	19/6090	55/18639	0.345454545454545	1.05729511867443	0.433089528568158	0.800594497244888
GO:0016881	acid-amino acid ligase activity	8/6090	22/18639	0.363636363636364	1.11294223018361	0.433509684097668	0.800594497244888
GO:0140517	protein-RNA adaptor activity	8/6090	22/18639	0.363636363636364	1.11294223018361	0.433509684097668	0.800594497244888
GO:0017056	structural constituent of nuclear pore	9/6090	25/18639	0.36	1.10181280788177	0.434269970022384	0.800679284007768
GO:0045499	chemorepellent activity	10/6090	28/18639	0.357142857142857	1.09306826178747	0.434721066863024	0.800679284007768
GO:0052689	carboxylic ester hydrolase activity	31/6090	92/18639	0.33695652173913	1.03128614264296	0.455913237171969	0.838587400099445
GO:0019842	vitamin binding	50/6090	150/18639	0.333333333333333	1.02019704433498	0.461974211813685	0.84852139304176
GO:0031491	nucleosome binding	25/6090	74/18639	0.337837837837838	1.03398349088004	0.462549143659591	0.84852139304176
GO:0038024	cargo receptor activity	22/6090	65/18639	0.338461538461538	1.03589238347859	0.466284370363898	0.854232966506662
GO:0015459	potassium channel regulator activity	20/6090	59/18639	0.338983050847458	1.03748851966269	0.468979703752261	0.858026781565389
GO:0032813	tumor necrosis factor receptor superfamily binding	17/6090	50/18639	0.34	1.04060098522167	0.473418246906148	0.864995573469477
GO:0001784	phosphotyrosine residue binding	16/6090	47/18639	0.340425531914894	1.04190336442721	0.475028082915807	0.866784310659122
GO:0008201	heparin binding	57/6090	172/18639	0.331395348837209	1.01426566617024	0.476670006781733	0.868626776283954
GO:0042169	SH2 domain binding	14/6090	41/18639	0.341463414634146	1.04507989907485	0.478496324872863	0.870799934271939
GO:0042887	amide transmembrane transporter activity	13/6090	38/18639	0.342105263157895	1.04704433497537	0.480379630309343	0.873070915403488
GO:0015106	bicarbonate transmembrane transporter activity	11/6090	32/18639	0.34375	1.05207820197044	0.484532506643745	0.878831020109435
GO:0004629	phospholipase C activity	10/6090	29/18639	0.344827586206897	1.05537625276032	0.486853364718841	0.878831020109435
GO:0051861	glycolipid binding	10/6090	29/18639	0.344827586206897	1.05537625276032	0.486853364718841	0.878831020109435
GO:0004435	phosphatidylinositol phospholipase C activity	9/6090	26/18639	0.346153846153846	1.05943539219401	0.489386053680855	0.878831020109435
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	9/6090	26/18639	0.346153846153846	1.05943539219401	0.489386053680855	0.878831020109435
GO:0008143	poly(A) binding	9/6090	26/18639	0.346153846153846	1.05943539219401	0.489386053680855	0.878831020109435
GO:0140101	catalytic activity, acting on a tRNA	46/6090	139/18639	0.330935251798561	1.01285749725343	0.489792660014001	0.878831020109435
GO:0003887	DNA-directed DNA polymerase activity	8/6090	23/18639	0.347826086956522	1.06455343756693	0.492185093679168	0.878831020109435
GO:0004602	glutathione peroxidase activity	8/6090	23/18639	0.347826086956522	1.06455343756693	0.492185093679168	0.878831020109435
GO:0016798	hydrolase activity, acting on glycosyl bonds	43/6090	130/18639	0.330769230769231	1.01234937476317	0.493883903139721	0.878831020109435
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	7/6090	20/18639	0.35	1.07120689655172	0.495329448804892	0.878831020109435
GO:0016505	peptidase activator activity involved in apoptotic process	7/6090	20/18639	0.35	1.07120689655172	0.495329448804892	0.878831020109435
GO:0015108	chloride transmembrane transporter activity	40/6090	121/18639	0.330578512396694	1.01176566380328	0.498260147799188	0.878831020109435
GO:0004550	nucleoside diphosphate kinase activity	6/6090	17/18639	0.352941176470588	1.08020863517821	0.498939453696007	0.878831020109435
GO:0004659	prenyltransferase activity	6/6090	17/18639	0.352941176470588	1.08020863517821	0.498939453696007	0.878831020109435
GO:0017110	nucleoside diphosphate phosphatase activity	6/6090	17/18639	0.352941176470588	1.08020863517821	0.498939453696007	0.878831020109435
GO:0032977	membrane insertase activity	6/6090	17/18639	0.352941176470588	1.08020863517821	0.498939453696007	0.878831020109435
GO:0070403	NAD+ binding	6/6090	17/18639	0.352941176470588	1.08020863517821	0.498939453696007	0.878831020109435
GO:0141108	transporter regulator activity	56/6090	170/18639	0.329411764705882	1.00819472616633	0.499208896608167	0.878831020109435
GO:0005313	L-glutamate transmembrane transporter activity	5/6090	14/18639	0.357142857142857	1.09306826178747	0.503211098489053	0.878831020109435
GO:0008174	mRNA methyltransferase activity	5/6090	14/18639	0.357142857142857	1.09306826178747	0.503211098489053	0.878831020109435
GO:0015926	glucosidase activity	5/6090	14/18639	0.357142857142857	1.09306826178747	0.503211098489053	0.878831020109435
GO:0098847	sequence-specific single stranded DNA binding	5/6090	14/18639	0.357142857142857	1.09306826178747	0.503211098489053	0.878831020109435
GO:1901474	azole transmembrane transporter activity	5/6090	14/18639	0.357142857142857	1.09306826178747	0.503211098489053	0.878831020109435
GO:0004620	phospholipase activity	36/6090	109/18639	0.330275229357798	1.01083743842365	0.504625856835946	0.878831020109435
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	20/6090	60/18639	0.333333333333333	1.02019704433498	0.505065567882613	0.878831020109435
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	4/6090	11/18639	0.363636363636364	1.11294223018361	0.508493930849345	0.878831020109435
GO:0000099	sulfur amino acid transmembrane transporter activity	4/6090	11/18639	0.363636363636364	1.11294223018361	0.508493930849345	0.878831020109435
GO:0005225	volume-sensitive anion channel activity	4/6090	11/18639	0.363636363636364	1.11294223018361	0.508493930849345	0.878831020109435
GO:0008046	axon guidance receptor activity	4/6090	11/18639	0.363636363636364	1.11294223018361	0.508493930849345	0.878831020109435
GO:0008271	secondary active sulfate transmembrane transporter activity	4/6090	11/18639	0.363636363636364	1.11294223018361	0.508493930849345	0.878831020109435
GO:0010854	adenylate cyclase regulator activity	4/6090	11/18639	0.363636363636364	1.11294223018361	0.508493930849345	0.878831020109435
GO:0015217	ADP transmembrane transporter activity	4/6090	11/18639	0.363636363636364	1.11294223018361	0.508493930849345	0.878831020109435
GO:0016176	superoxide-generating NADPH oxidase activator activity	4/6090	11/18639	0.363636363636364	1.11294223018361	0.508493930849345	0.878831020109435
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	4/6090	11/18639	0.363636363636364	1.11294223018361	0.508493930849345	0.878831020109435
GO:0019206	nucleoside kinase activity	4/6090	11/18639	0.363636363636364	1.11294223018361	0.508493930849345	0.878831020109435
GO:0032404	mismatch repair complex binding	4/6090	11/18639	0.363636363636364	1.11294223018361	0.508493930849345	0.878831020109435
GO:0070697	activin receptor binding	4/6090	11/18639	0.363636363636364	1.11294223018361	0.508493930849345	0.878831020109435
GO:1900750	oligopeptide binding	4/6090	11/18639	0.363636363636364	1.11294223018361	0.508493930849345	0.878831020109435
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	18/6090	54/18639	0.333333333333333	1.02019704433498	0.50991217419324	0.879070674205158
GO:0050661	NADP binding	18/6090	54/18639	0.333333333333333	1.02019704433498	0.50991217419324	0.879070674205158
GO:0030544	Hsp70 protein binding	17/6090	51/18639	0.333333333333333	1.02019704433498	0.512550676497842	0.882512067052676
GO:0042562	hormone binding	31/6090	94/18639	0.329787234042553	1.00934388428886	0.513668559666658	0.88332991361951
GO:0016247	channel regulator activity	55/6090	168/18639	0.327380952380952	1.00197923997185	0.52203825771697	0.896600707628896
GO:0019239	deaminase activity	11/6090	33/18639	0.333333333333333	1.02019704433498	0.533091889838566	0.914442267962784
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	22/6090	67/18639	0.328358208955224	1.00497022277774	0.534667638083586	0.916001664247939
GO:0008187	poly-pyrimidine tract binding	10/6090	30/18639	0.333333333333333	1.02019704433498	0.537748886137078	0.918988768099932
GO:0098918	structural constituent of synapse	10/6090	30/18639	0.333333333333333	1.02019704433498	0.537748886137078	0.918988768099932
GO:0004867	serine-type endopeptidase inhibitor activity	31/6090	95/18639	0.326315789473684	0.99871921182266	0.542138037187557	0.923681504062383
GO:0001671	ATPase activator activity	9/6090	27/18639	0.333333333333333	1.02019704433498	0.542988326198292	0.923681504062383
GO:0035255	ionotropic glutamate receptor binding	9/6090	27/18639	0.333333333333333	1.02019704433498	0.542988326198292	0.923681504062383
GO:0004518	nuclease activity	68/6090	209/18639	0.325358851674641	0.995790416480072	0.543183883029407	0.923681504062383
GO:0003727	single-stranded RNA binding	29/6090	89/18639	0.325842696629214	0.997271268057785	0.547082240475521	0.928929751798359
GO:0001091	RNA polymerase II general transcription initiation factor binding	8/6090	24/18639	0.333333333333333	1.02019704433498	0.548974496695974	0.928929751798359
GO:0004806	triacylglycerol lipase activity	8/6090	24/18639	0.333333333333333	1.02019704433498	0.548974496695974	0.928929751798359
GO:0030215	semaphorin receptor binding	8/6090	24/18639	0.333333333333333	1.02019704433498	0.548974496695974	0.928929751798359
GO:0050660	flavin adenine dinucleotide binding	28/6090	86/18639	0.325581395348837	0.996471531676023	0.549697883043926	0.92900970639896
GO:0005254	chloride channel activity	27/6090	83/18639	0.325301204819277	0.995613983025699	0.552419725541563	0.932462779968192
GO:0000049	tRNA binding	26/6090	80/18639	0.325	0.994692118226601	0.555256868008302	0.934972164944552
GO:0008373	sialyltransferase activity	7/6090	21/18639	0.333333333333333	1.02019704433498	0.555947786579111	0.934972164944552
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	7/6090	21/18639	0.333333333333333	1.02019704433498	0.555947786579111	0.934972164944552
GO:0008308	voltage-gated monoatomic anion channel activity	6/6090	18/18639	0.333333333333333	1.02019704433498	0.564277745170661	0.940919444010301
GO:0008409	5'-3' exonuclease activity	6/6090	18/18639	0.333333333333333	1.02019704433498	0.564277745170661	0.940919444010301
GO:0008525	phosphatidylcholine transporter activity	6/6090	18/18639	0.333333333333333	1.02019704433498	0.564277745170661	0.940919444010301
GO:0022851	GABA-gated chloride ion channel activity	6/6090	18/18639	0.333333333333333	1.02019704433498	0.564277745170661	0.940919444010301
GO:0030228	lipoprotein particle receptor activity	6/6090	18/18639	0.333333333333333	1.02019704433498	0.564277745170661	0.940919444010301
GO:0034185	apolipoprotein binding	6/6090	18/18639	0.333333333333333	1.02019704433498	0.564277745170661	0.940919444010301
GO:0070628	proteasome binding	6/6090	18/18639	0.333333333333333	1.02019704433498	0.564277745170661	0.940919444010301
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	54/6090	167/18639	0.323353293413174	0.989652222648299	0.566395470826333	0.943305911412584
GO:0015036	disulfide oxidoreductase activity	13/6090	40/18639	0.325	0.994692118226601	0.568569965964608	0.944637404154017
GO:0050997	quaternary ammonium group binding	13/6090	40/18639	0.325	0.994692118226601	0.568569965964608	0.944637404154017
GO:0160215	deacylase activity	21/6090	65/18639	0.323076923076923	0.988806366047745	0.571585499021752	0.946593894915399
GO:0030551	cyclic nucleotide binding	12/6090	37/18639	0.324324324324324	0.992624151244841	0.573999071364461	0.946593894915399
GO:0004467	long-chain fatty acid-CoA ligase activity	5/6090	15/18639	0.333333333333333	1.02019704433498	0.574570093420264	0.946593894915399
GO:0042809	nuclear vitamin D receptor binding	5/6090	15/18639	0.333333333333333	1.02019704433498	0.574570093420264	0.946593894915399
GO:0047372	monoacylglycerol lipase activity	5/6090	15/18639	0.333333333333333	1.02019704433498	0.574570093420264	0.946593894915399
GO:0048531	beta-1,3-galactosyltransferase activity	5/6090	15/18639	0.333333333333333	1.02019704433498	0.574570093420264	0.946593894915399
GO:0051371	muscle alpha-actinin binding	5/6090	15/18639	0.333333333333333	1.02019704433498	0.574570093420264	0.946593894915399
GO:0003697	single-stranded DNA binding	39/6090	121/18639	0.322314049586777	0.986471522208199	0.575500318742398	0.946990943655155
GO:0008175	tRNA methyltransferase activity	11/6090	34/18639	0.323529411764706	0.990191248913359	0.580000582168507	0.953254545334364
GO:0003995	acyl-CoA dehydrogenase activity	4/6090	12/18639	0.333333333333333	1.02019704433498	0.587907686178365	0.954828795282593
GO:0004000	adenosine deaminase activity	4/6090	12/18639	0.333333333333333	1.02019704433498	0.587907686178365	0.954828795282593
GO:0004859	phospholipase inhibitor activity	4/6090	12/18639	0.333333333333333	1.02019704433498	0.587907686178365	0.954828795282593
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	4/6090	12/18639	0.333333333333333	1.02019704433498	0.587907686178365	0.954828795282593
GO:0015269	calcium-activated potassium channel activity	4/6090	12/18639	0.333333333333333	1.02019704433498	0.587907686178365	0.954828795282593
GO:0016423	tRNA (guanine) methyltransferase activity	4/6090	12/18639	0.333333333333333	1.02019704433498	0.587907686178365	0.954828795282593
GO:0042301	phosphate ion binding	4/6090	12/18639	0.333333333333333	1.02019704433498	0.587907686178365	0.954828795282593
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	4/6090	12/18639	0.333333333333333	1.02019704433498	0.587907686178365	0.954828795282593
GO:0070008	serine-type exopeptidase activity	4/6090	12/18639	0.333333333333333	1.02019704433498	0.587907686178365	0.954828795282593
GO:1990459	transferrin receptor binding	4/6090	12/18639	0.333333333333333	1.02019704433498	0.587907686178365	0.954828795282593
GO:0005253	monoatomic anion channel activity	33/6090	103/18639	0.320388349514563	0.980577741642355	0.59150901826009	0.959543555005151
GO:0015175	neutral L-amino acid transmembrane transporter activity	13/6090	41/18639	0.317073170731707	0.97043133485522	0.610389870757204	0.989004342476885
GO:0034062	5'-3' RNA polymerase activity	7/6090	22/18639	0.318181818181818	0.973824451410658	0.613085567737118	0.989870235100823
GO:0070034	telomerase RNA binding	7/6090	22/18639	0.318181818181818	0.973824451410658	0.613085567737118	0.989870235100823
GO:0097747	RNA polymerase activity	7/6090	22/18639	0.318181818181818	0.973824451410658	0.613085567737118	0.989870235100823
GO:0043531	ADP binding	12/6090	38/18639	0.315789473684211	0.966502463054187	0.617208044159131	0.995356634594655
GO:0008168	methyltransferase activity	65/6090	204/18639	0.318627450980392	0.97518835120255	0.623822495692333	0.998846232681239
GO:0005343	organic acid:sodium symporter activity	11/6090	35/18639	0.314285714285714	0.961900070372977	0.6247413810672	0.998846232681239
GO:0004890	GABA-A receptor activity	6/6090	19/18639	0.315789473684211	0.966502463054187	0.625187598330324	0.998846232681239
GO:0008381	mechanosensitive monoatomic ion channel activity	6/6090	19/18639	0.315789473684211	0.966502463054187	0.625187598330324	0.998846232681239
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	6/6090	19/18639	0.315789473684211	0.966502463054187	0.625187598330324	0.998846232681239
GO:0022821	solute:potassium antiporter activity	6/6090	19/18639	0.315789473684211	0.966502463054187	0.625187598330324	0.998846232681239
GO:0030506	ankyrin binding	6/6090	19/18639	0.315789473684211	0.966502463054187	0.625187598330324	0.998846232681239
GO:0042834	peptidoglycan binding	6/6090	19/18639	0.315789473684211	0.966502463054187	0.625187598330324	0.998846232681239
GO:0031369	translation initiation factor binding	10/6090	32/18639	0.3125	0.956434729064039	0.633141790049343	1
GO:0051059	NF-kappaB binding	10/6090	32/18639	0.3125	0.956434729064039	0.633141790049343	1
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	15/6090	48/18639	0.3125	0.956434729064039	0.636229905157224	1
GO:0046873	metal ion transmembrane transporter activity	144/6090	450/18639	0.32	0.979389162561576	0.638427365642168	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	5/6090	16/18639	0.3125	0.956434729064039	0.640084564296732	1
GO:0005159	insulin-like growth factor receptor binding	5/6090	16/18639	0.3125	0.956434729064039	0.640084564296732	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	5/6090	16/18639	0.3125	0.956434729064039	0.640084564296732	1
GO:0019841	retinol binding	5/6090	16/18639	0.3125	0.956434729064039	0.640084564296732	1
GO:0022858	alanine transmembrane transporter activity	5/6090	16/18639	0.3125	0.956434729064039	0.640084564296732	1
GO:0043023	ribosomal large subunit binding	5/6090	16/18639	0.3125	0.956434729064039	0.640084564296732	1
GO:0055102	lipase inhibitor activity	5/6090	16/18639	0.3125	0.956434729064039	0.640084564296732	1
GO:0097027	ubiquitin-protein transferase activator activity	5/6090	16/18639	0.3125	0.956434729064039	0.640084564296732	1
GO:0106222	lncRNA binding	9/6090	29/18639	0.310344827586207	0.949838627484287	0.642611571196954	1
GO:0001540	amyloid-beta binding	26/6090	83/18639	0.313253012048193	0.958739391061784	0.643477461828528	1
GO:0008509	monoatomic anion transmembrane transporter activity	47/6090	149/18639	0.315436241610738	0.965421364102225	0.645856237136998	1
GO:0008238	exopeptidase activity	32/6090	102/18639	0.313725490196078	0.960185453491741	0.646570478713718	1
GO:0004520	DNA endonuclease activity	13/6090	42/18639	0.30952380952381	0.947325826882477	0.650195241272075	1
GO:0004540	RNA nuclease activity	38/6090	121/18639	0.31404958677686	0.961177380613117	0.650264362162896	1
GO:0015103	inorganic anion transmembrane transporter activity	52/6090	165/18639	0.315151515151515	0.964549932825795	0.653151607785049	1
GO:0015145	monosaccharide transmembrane transporter activity	8/6090	26/18639	0.307692307692308	0.9417203486169	0.65342733917363	1
GO:0030247	polysaccharide binding	8/6090	26/18639	0.307692307692308	0.9417203486169	0.65342733917363	1
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	12/6090	39/18639	0.307692307692308	0.9417203486169	0.65814974327067	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	4/6090	13/18639	0.307692307692308	0.9417203486169	0.659196883263688	1
GO:0008417	fucosyltransferase activity	4/6090	13/18639	0.307692307692308	0.9417203486169	0.659196883263688	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	4/6090	13/18639	0.307692307692308	0.9417203486169	0.659196883263688	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	4/6090	13/18639	0.307692307692308	0.9417203486169	0.659196883263688	1
GO:0035325	Toll-like receptor binding	4/6090	13/18639	0.307692307692308	0.9417203486169	0.659196883263688	1
GO:0089720	caspase binding	4/6090	13/18639	0.307692307692308	0.9417203486169	0.659196883263688	1
GO:0097157	pre-mRNA intronic binding	4/6090	13/18639	0.307692307692308	0.9417203486169	0.659196883263688	1
GO:0005283	amino acid:sodium symporter activity	7/6090	23/18639	0.304347826086957	0.931484257871064	0.665979525137471	1
GO:0099186	structural constituent of postsynapse	7/6090	23/18639	0.304347826086957	0.931484257871064	0.665979525137471	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	11/6090	36/18639	0.305555555555556	0.935180623973728	0.666911339607761	1
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	11/6090	36/18639	0.305555555555556	0.935180623973728	0.666911339607761	1
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	11/6090	36/18639	0.305555555555556	0.935180623973728	0.666911339607761	1
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	11/6090	36/18639	0.305555555555556	0.935180623973728	0.666911339607761	1
GO:0060590	ATPase regulator activity	15/6090	49/18639	0.306122448979592	0.936915652960692	0.672130059623316	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	10/6090	33/18639	0.303030303030303	0.927451858486341	0.676641746662724	1
GO:0019956	chemokine binding	10/6090	33/18639	0.303030303030303	0.927451858486341	0.676641746662724	1
GO:0015179	L-amino acid transmembrane transporter activity	19/6090	62/18639	0.306451612903226	0.937923089146671	0.678662313005772	1
GO:0004180	carboxypeptidase activity	14/6090	46/18639	0.304347826086957	0.931484257871064	0.67960912576149	1
GO:0016004	phospholipase activator activity	6/6090	20/18639	0.3	0.918177339901478	0.680841090984081	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	6/6090	20/18639	0.3	0.918177339901478	0.680841090984081	1
GO:0043024	ribosomal small subunit binding	6/6090	20/18639	0.3	0.918177339901478	0.680841090984081	1
GO:0140939	histone H4 methyltransferase activity	6/6090	20/18639	0.3	0.918177339901478	0.680841090984081	1
GO:0061134	peptidase regulator activity	71/6090	226/18639	0.314159292035398	0.961513143554645	0.680998422858243	1
GO:0001094	TFIID-class transcription factor complex binding	3/6090	10/18639	0.3	0.918177339901478	0.685242522843489	1
GO:0004090	carbonyl reductase (NADPH) activity	3/6090	10/18639	0.3	0.918177339901478	0.685242522843489	1
GO:0008401	retinoic acid 4-hydroxylase activity	3/6090	10/18639	0.3	0.918177339901478	0.685242522843489	1
GO:0008641	ubiquitin-like modifier activating enzyme activity	3/6090	10/18639	0.3	0.918177339901478	0.685242522843489	1
GO:0015187	glycine transmembrane transporter activity	3/6090	10/18639	0.3	0.918177339901478	0.685242522843489	1
GO:0019531	oxalate transmembrane transporter activity	3/6090	10/18639	0.3	0.918177339901478	0.685242522843489	1
GO:0031434	mitogen-activated protein kinase kinase binding	3/6090	10/18639	0.3	0.918177339901478	0.685242522843489	1
GO:0032356	oxidized DNA binding	3/6090	10/18639	0.3	0.918177339901478	0.685242522843489	1
GO:0043208	glycosphingolipid binding	3/6090	10/18639	0.3	0.918177339901478	0.685242522843489	1
GO:0051880	G-quadruplex DNA binding	3/6090	10/18639	0.3	0.918177339901478	0.685242522843489	1
GO:0140135	mechanosensitive monoatomic cation channel activity	3/6090	10/18639	0.3	0.918177339901478	0.685242522843489	1
GO:1990757	ubiquitin ligase activator activity	3/6090	10/18639	0.3	0.918177339901478	0.685242522843489	1
GO:1990763	arrestin family protein binding	3/6090	10/18639	0.3	0.918177339901478	0.685242522843489	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	9/6090	30/18639	0.3	0.918177339901478	0.687552721936901	1
GO:0048019	receptor antagonist activity	9/6090	30/18639	0.3	0.918177339901478	0.687552721936901	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	28/6090	91/18639	0.307692307692308	0.9417203486169	0.688004330517638	1
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	12/6090	40/18639	0.3	0.918177339901478	0.696541076401839	1
GO:0004866	endopeptidase inhibitor activity	50/6090	161/18639	0.31055900621118	0.95049414068476	0.69731176589407	1
GO:0005246	calcium channel regulator activity	16/6090	53/18639	0.30188679245283	0.92395204015243	0.698453756223417	1
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	5/6090	17/18639	0.294117647058824	0.900173862648508	0.698895027047034	1
GO:0016805	dipeptidase activity	5/6090	17/18639	0.294117647058824	0.900173862648508	0.698895027047034	1
GO:0048038	quinone binding	5/6090	17/18639	0.294117647058824	0.900173862648508	0.698895027047034	1
GO:0005044	scavenger receptor activity	8/6090	27/18639	0.296296296296296	0.906841817186645	0.699927976215878	1
GO:0016405	CoA-ligase activity	8/6090	27/18639	0.296296296296296	0.906841817186645	0.699927976215878	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	8/6090	27/18639	0.296296296296296	0.906841817186645	0.699927976215878	1
GO:0030280	structural constituent of skin epidermis	11/6090	37/18639	0.297297297297297	0.909905471974438	0.706220376172234	1
GO:0042805	actinin binding	11/6090	37/18639	0.297297297297297	0.909905471974438	0.706220376172234	1
GO:0015293	symporter activity	45/6090	146/18639	0.308219178082192	0.943332883460423	0.71237851357279	1
GO:0004519	endonuclease activity	39/6090	127/18639	0.307086614173228	0.939866568403087	0.712597667004984	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	7/6090	24/18639	0.291666666666667	0.892672413793103	0.714158066260441	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	7/6090	24/18639	0.291666666666667	0.892672413793103	0.714158066260441	1
GO:0005315	phosphate transmembrane transporter activity	7/6090	24/18639	0.291666666666667	0.892672413793103	0.714158066260441	1
GO:0015149	hexose transmembrane transporter activity	7/6090	24/18639	0.291666666666667	0.892672413793103	0.714158066260441	1
GO:0015295	solute:proton symporter activity	7/6090	24/18639	0.291666666666667	0.892672413793103	0.714158066260441	1
GO:0048027	mRNA 5'-UTR binding	7/6090	24/18639	0.291666666666667	0.892672413793103	0.714158066260441	1
GO:0055056	D-glucose transmembrane transporter activity	7/6090	24/18639	0.291666666666667	0.892672413793103	0.714158066260441	1
GO:0060229	lipase activator activity	7/6090	24/18639	0.291666666666667	0.892672413793103	0.714158066260441	1
GO:0015035	protein-disulfide reductase activity	10/6090	34/18639	0.294117647058824	0.900173862648508	0.716908898535314	1
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	10/6090	34/18639	0.294117647058824	0.900173862648508	0.716908898535314	1
GO:0051427	hormone receptor binding	10/6090	34/18639	0.294117647058824	0.900173862648508	0.716908898535314	1
GO:0090482	vitamin transmembrane transporter activity	10/6090	34/18639	0.294117647058824	0.900173862648508	0.716908898535314	1
GO:0008559	ABC-type xenobiotic transporter activity	4/6090	14/18639	0.285714285714286	0.874454609429979	0.721591197173542	1
GO:0015386	potassium:proton antiporter activity	4/6090	14/18639	0.285714285714286	0.874454609429979	0.721591197173542	1
GO:0016530	metallochaperone activity	4/6090	14/18639	0.285714285714286	0.874454609429979	0.721591197173542	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	4/6090	14/18639	0.285714285714286	0.874454609429979	0.721591197173542	1
GO:0030983	mismatched DNA binding	4/6090	14/18639	0.285714285714286	0.874454609429979	0.721591197173542	1
GO:1901612	cardiolipin binding	4/6090	14/18639	0.285714285714286	0.874454609429979	0.721591197173542	1
GO:0030547	signaling receptor inhibitor activity	13/6090	44/18639	0.295454545454545	0.904265562024183	0.722746365402637	1
GO:0016878	acid-thiol ligase activity	9/6090	31/18639	0.290322580645161	0.888558716033688	0.728810085417186	1
GO:0015174	basic amino acid transmembrane transporter activity	6/6090	21/18639	0.285714285714286	0.874454609429979	0.730798412746069	1
GO:0036122	BMP binding	6/6090	21/18639	0.285714285714286	0.874454609429979	0.730798412746069	1
GO:0140312	cargo adaptor activity	6/6090	21/18639	0.285714285714286	0.874454609429979	0.730798412746069	1
GO:0016877	ligase activity, forming carbon-sulfur bonds	12/6090	41/18639	0.292682926829268	0.895782770635588	0.732189851151343	1
GO:0004536	DNA nuclease activity	19/6090	64/18639	0.296875	0.908612992610837	0.736977889622402	1
GO:0051119	sugar transmembrane transporter activity	8/6090	28/18639	0.285714285714286	0.874454609429979	0.742190039717283	1
GO:0051393	alpha-actinin binding	8/6090	28/18639	0.285714285714286	0.874454609429979	0.742190039717283	1
GO:0000400	four-way junction DNA binding	5/6090	18/18639	0.277777777777778	0.850164203612479	0.750670904691793	1
GO:0015280	ligand-gated sodium channel activity	5/6090	18/18639	0.277777777777778	0.850164203612479	0.750670904691793	1
GO:0031690	adrenergic receptor binding	5/6090	18/18639	0.277777777777778	0.850164203612479	0.750670904691793	1
GO:0035615	clathrin adaptor activity	5/6090	18/18639	0.277777777777778	0.850164203612479	0.750670904691793	1
GO:0050811	GABA receptor binding	5/6090	18/18639	0.277777777777778	0.850164203612479	0.750670904691793	1
GO:0099602	neurotransmitter receptor regulator activity	5/6090	18/18639	0.277777777777778	0.850164203612479	0.750670904691793	1
GO:1901611	phosphatidylglycerol binding	5/6090	18/18639	0.277777777777778	0.850164203612479	0.750670904691793	1
GO:0005114	type II transforming growth factor beta receptor binding	3/6090	11/18639	0.272727272727273	0.834706672637707	0.751523244841292	1
GO:0008172	S-methyltransferase activity	3/6090	11/18639	0.272727272727273	0.834706672637707	0.751523244841292	1
GO:0008503	benzodiazepine receptor activity	3/6090	11/18639	0.272727272727273	0.834706672637707	0.751523244841292	1
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	3/6090	11/18639	0.272727272727273	0.834706672637707	0.751523244841292	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	3/6090	11/18639	0.272727272727273	0.834706672637707	0.751523244841292	1
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	3/6090	11/18639	0.272727272727273	0.834706672637707	0.751523244841292	1
GO:0034511	U3 snoRNA binding	3/6090	11/18639	0.272727272727273	0.834706672637707	0.751523244841292	1
GO:0050786	RAGE receptor binding	3/6090	11/18639	0.272727272727273	0.834706672637707	0.751523244841292	1
GO:0070990	snRNP binding	3/6090	11/18639	0.272727272727273	0.834706672637707	0.751523244841292	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	3/6090	11/18639	0.272727272727273	0.834706672637707	0.751523244841292	1
GO:0140031	phosphorylation-dependent protein binding	3/6090	11/18639	0.272727272727273	0.834706672637707	0.751523244841292	1
GO:0034061	DNA polymerase activity	10/6090	35/18639	0.285714285714286	0.874454609429979	0.75377590552256	1
GO:1901681	sulfur compound binding	85/6090	275/18639	0.309090909090909	0.946000895656068	0.754698155000704	1
GO:0016741	transferase activity, transferring one-carbon groups	66/6090	215/18639	0.306976744186047	0.939530301294536	0.754894750627015	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	7/6090	25/18639	0.28	0.856965517241379	0.757404443007011	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	7/6090	25/18639	0.28	0.856965517241379	0.757404443007011	1
GO:0047617	fatty acyl-CoA hydrolase activity	7/6090	25/18639	0.28	0.856965517241379	0.757404443007011	1
GO:0008514	organic anion transmembrane transporter activity	83/6090	269/18639	0.308550185873606	0.94434596297178	0.75872157643045	1
GO:0016859	cis-trans isomerase activity	12/6090	42/18639	0.285714285714286	0.874454609429979	0.76498769510305	1
GO:0008970	phospholipase A1 activity	6/6090	22/18639	0.272727272727273	0.834706672637707	0.774940729624425	1
GO:0015377	chloride:monoatomic cation symporter activity	6/6090	22/18639	0.272727272727273	0.834706672637707	0.774940729624425	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	6/6090	22/18639	0.272727272727273	0.834706672637707	0.774940729624425	1
GO:0031683	G-protein beta/gamma-subunit complex binding	6/6090	22/18639	0.272727272727273	0.834706672637707	0.774940729624425	1
GO:0004129	cytochrome-c oxidase activity	4/6090	15/18639	0.266666666666667	0.81615763546798	0.775053416720189	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	4/6090	15/18639	0.266666666666667	0.81615763546798	0.775053416720189	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	4/6090	15/18639	0.266666666666667	0.81615763546798	0.775053416720189	1
GO:0008242	omega peptidase activity	4/6090	15/18639	0.266666666666667	0.81615763546798	0.775053416720189	1
GO:0015116	sulfate transmembrane transporter activity	4/6090	15/18639	0.266666666666667	0.81615763546798	0.775053416720189	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	4/6090	15/18639	0.266666666666667	0.81615763546798	0.775053416720189	1
GO:0030553	cGMP binding	4/6090	15/18639	0.266666666666667	0.81615763546798	0.775053416720189	1
GO:0050780	dopamine receptor binding	4/6090	15/18639	0.266666666666667	0.81615763546798	0.775053416720189	1
GO:0140161	monocarboxylate:sodium symporter activity	4/6090	15/18639	0.266666666666667	0.81615763546798	0.775053416720189	1
GO:0004181	metallocarboxypeptidase activity	8/6090	29/18639	0.275862068965517	0.844301002208255	0.780124694391694	1
GO:0030414	peptidase inhibitor activity	51/6090	169/18639	0.301775147928994	0.923610341912729	0.780385135777635	1
GO:0015399	primary active transmembrane transporter activity	50/6090	166/18639	0.301204819277108	0.921864799097869	0.783431792515874	1
GO:0004190	aspartic-type endopeptidase activity	10/6090	36/18639	0.277777777777778	0.850164203612479	0.787185353951329	1
GO:0005245	voltage-gated calcium channel activity	12/6090	43/18639	0.27906976744186	0.854118455722305	0.794900672316023	1
GO:0022840	leak channel activity	5/6090	19/18639	0.263157894736842	0.805418719211823	0.795486371249461	1
GO:0022842	narrow pore channel activity	5/6090	19/18639	0.263157894736842	0.805418719211823	0.795486371249461	1
GO:0031420	alkali metal ion binding	5/6090	19/18639	0.263157894736842	0.805418719211823	0.795486371249461	1
GO:0070003	threonine-type peptidase activity	5/6090	19/18639	0.263157894736842	0.805418719211823	0.795486371249461	1
GO:0120227	acyl-CoA binding	5/6090	19/18639	0.263157894736842	0.805418719211823	0.795486371249461	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	7/6090	26/18639	0.269230769230769	0.824005305039788	0.795711797050888	1
GO:0004529	DNA exonuclease activity	7/6090	26/18639	0.269230769230769	0.824005305039788	0.795711797050888	1
GO:0016289	acyl-CoA hydrolase activity	7/6090	26/18639	0.269230769230769	0.824005305039788	0.795711797050888	1
GO:0004896	cytokine receptor activity	28/6090	96/18639	0.291666666666667	0.892672413793103	0.799483074185166	1
GO:0015144	carbohydrate transmembrane transporter activity	11/6090	40/18639	0.275	0.841662561576355	0.805610259090772	1
GO:0004126	cytidine deaminase activity	3/6090	12/18639	0.25	0.765147783251232	0.806061764395601	1
GO:0008179	adenylate cyclase binding	3/6090	12/18639	0.25	0.765147783251232	0.806061764395601	1
GO:0008504	monoamine transmembrane transporter activity	3/6090	12/18639	0.25	0.765147783251232	0.806061764395601	1
GO:0010853	cyclase activator activity	3/6090	12/18639	0.25	0.765147783251232	0.806061764395601	1
GO:0015166	polyol transmembrane transporter activity	3/6090	12/18639	0.25	0.765147783251232	0.806061764395601	1
GO:0015368	calcium:monoatomic cation antiporter activity	3/6090	12/18639	0.25	0.765147783251232	0.806061764395601	1
GO:0016273	arginine N-methyltransferase activity	3/6090	12/18639	0.25	0.765147783251232	0.806061764395601	1
GO:0016274	protein-arginine N-methyltransferase activity	3/6090	12/18639	0.25	0.765147783251232	0.806061764395601	1
GO:0016801	hydrolase activity, acting on ether bonds	3/6090	12/18639	0.25	0.765147783251232	0.806061764395601	1
GO:0016803	ether hydrolase activity	3/6090	12/18639	0.25	0.765147783251232	0.806061764395601	1
GO:0016840	carbon-nitrogen lyase activity	3/6090	12/18639	0.25	0.765147783251232	0.806061764395601	1
GO:0031406	carboxylic acid binding	56/6090	187/18639	0.299465240641711	0.916540660151208	0.809305996928713	1
GO:0008173	RNA methyltransferase activity	19/6090	67/18639	0.283582089552239	0.867928828762591	0.810979641440109	1
GO:0099095	ligand-gated monoatomic anion channel activity	13/6090	47/18639	0.276595744680851	0.846546483597107	0.812054766683278	1
GO:0061135	endopeptidase regulator activity	55/6090	184/18639	0.298913043478261	0.914850610409081	0.812103462464416	1
GO:0016917	GABA receptor activity	6/6090	23/18639	0.260869565217391	0.798415078175198	0.813397625325703	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	6/6090	23/18639	0.260869565217391	0.798415078175198	0.813397625325703	1
GO:0016769	transferase activity, transferring nitrogenous groups	8/6090	30/18639	0.266666666666667	0.81615763546798	0.8137872298298	1
GO:0035925	mRNA 3'-UTR AU-rich region binding	8/6090	30/18639	0.266666666666667	0.81615763546798	0.8137872298298	1
GO:0070001	aspartic-type peptidase activity	10/6090	37/18639	0.27027027027027	0.827186792704034	0.817172382758401	1
GO:0051287	NAD binding	15/6090	54/18639	0.277777777777778	0.850164203612479	0.818733874645265	1
GO:0003688	DNA replication origin binding	4/6090	16/18639	0.25	0.765147783251232	0.820043034194674	1
GO:0008296	3'-5'-DNA exonuclease activity	4/6090	16/18639	0.25	0.765147783251232	0.820043034194674	1
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/6090	16/18639	0.25	0.765147783251232	0.820043034194674	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	4/6090	16/18639	0.25	0.765147783251232	0.820043034194674	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	4/6090	16/18639	0.25	0.765147783251232	0.820043034194674	1
GO:0016790	thiolester hydrolase activity	12/6090	44/18639	0.272727272727273	0.834706672637707	0.821958537408543	1
GO:0016836	hydro-lyase activity	17/6090	61/18639	0.278688524590164	0.852951627230881	0.825420508692521	1
GO:0016597	amino acid binding	14/6090	51/18639	0.274509803921569	0.840162271805274	0.827405925190365	1
GO:0010851	cyclase regulator activity	5/6090	20/18639	0.25	0.765147783251232	0.833701464671254	1
GO:0043177	organic acid binding	56/6090	189/18639	0.296296296296296	0.906841817186645	0.835049172581289	1
GO:0005506	iron ion binding	45/6090	154/18639	0.292207792207792	0.894328577826115	0.842260064853252	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	8/6090	31/18639	0.258064516129032	0.789829969807723	0.84334449745158	1
GO:0008327	methyl-CpG binding	8/6090	31/18639	0.258064516129032	0.789829969807723	0.84334449745158	1
GO:0047499	calcium-independent phospholipase A2 activity	8/6090	31/18639	0.258064516129032	0.789829969807723	0.84334449745158	1
GO:0072349	modified amino acid transmembrane transporter activity	8/6090	31/18639	0.258064516129032	0.789829969807723	0.84334449745158	1
GO:0015081	sodium ion transmembrane transporter activity	48/6090	164/18639	0.292682926829268	0.895782770635588	0.845652146848873	1
GO:0005540	hyaluronic acid binding	6/6090	24/18639	0.25	0.765147783251232	0.846477478347457	1
GO:0140612	DNA damage sensor activity	6/6090	24/18639	0.25	0.765147783251232	0.846477478347457	1
GO:0015171	amino acid transmembrane transporter activity	29/6090	102/18639	0.284313725490196	0.870168067226891	0.84674767513428	1
GO:0004465	lipoprotein lipase activity	3/6090	13/18639	0.230769230769231	0.706290261462675	0.850121228735175	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/6090	13/18639	0.230769230769231	0.706290261462675	0.850121228735175	1
GO:0061459	L-arginine transmembrane transporter activity	3/6090	13/18639	0.230769230769231	0.706290261462675	0.850121228735175	1
GO:1901338	catecholamine binding	3/6090	13/18639	0.230769230769231	0.706290261462675	0.850121228735175	1
GO:0016835	carbon-oxygen lyase activity	22/6090	79/18639	0.278481012658228	0.852316518052005	0.850355316396691	1
GO:0033293	monocarboxylic acid binding	22/6090	79/18639	0.278481012658228	0.852316518052005	0.850355316396691	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	16/6090	59/18639	0.271186440677966	0.829990815730149	0.8536810328141	1
GO:0004175	endopeptidase activity	123/6090	405/18639	0.303703703703704	0.929512862616311	0.853918777083663	1
GO:0031492	nucleosomal DNA binding	11/6090	42/18639	0.261904761904762	0.801583391977481	0.856498081224068	1
GO:0042056	chemoattractant activity	11/6090	42/18639	0.261904761904762	0.801583391977481	0.856498081224068	1
GO:0008429	phosphatidylethanolamine binding	4/6090	17/18639	0.235294117647059	0.720139090118806	0.857319344086255	1
GO:0030548	acetylcholine receptor regulator activity	4/6090	17/18639	0.235294117647059	0.720139090118806	0.857319344086255	1
GO:0036041	long-chain fatty acid binding	4/6090	17/18639	0.235294117647059	0.720139090118806	0.857319344086255	1
GO:0070492	oligosaccharide binding	4/6090	17/18639	0.235294117647059	0.720139090118806	0.857319344086255	1
GO:0008235	metalloexopeptidase activity	18/6090	66/18639	0.272727272727273	0.834706672637707	0.857987813907592	1
GO:0016866	intramolecular transferase activity	7/6090	28/18639	0.25	0.765147783251232	0.858251499218427	1
GO:0046625	sphingolipid binding	7/6090	28/18639	0.25	0.765147783251232	0.858251499218427	1
GO:0015294	solute:monoatomic cation symporter activity	33/6090	116/18639	0.28448275862069	0.870685408527264	0.85872946683856	1
GO:0170055	lipid transmembrane transporter activity	15/6090	56/18639	0.267857142857143	0.819801196340605	0.86150891274688	1
GO:0004521	RNA endonuclease activity	20/6090	73/18639	0.273972602739726	0.838518118631487	0.862434432935201	1
GO:0051428	peptide hormone receptor binding	5/6090	21/18639	0.238095238095238	0.728712174524982	0.865858668397875	1
GO:0061891	calcium ion sensor activity	5/6090	21/18639	0.238095238095238	0.728712174524982	0.865858668397875	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	19/6090	70/18639	0.271428571428571	0.83073187895848	0.868749363787593	1
GO:0047498	calcium-dependent phospholipase A2 activity	8/6090	32/18639	0.25	0.765147783251232	0.869044161487529	1
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	16/6090	60/18639	0.266666666666667	0.81615763546798	0.872224451973896	1
GO:0005251	delayed rectifier potassium channel activity	6/6090	25/18639	0.24	0.734541871921182	0.874605805297071	1
GO:0015645	fatty acid ligase activity	6/6090	25/18639	0.24	0.734541871921182	0.874605805297071	1
GO:0120515	fatty acid-CoA ligase activity	6/6090	25/18639	0.24	0.734541871921182	0.874605805297071	1
GO:0004601	peroxidase activity	15/6090	57/18639	0.263157894736842	0.805418719211823	0.879724229922318	1
GO:0005416	amino acid:monoatomic cation symporter activity	7/6090	29/18639	0.241379310344828	0.738763376932224	0.883110028026934	1
GO:0008474	palmitoyl-(protein) hydrolase activity	3/6090	14/18639	0.214285714285714	0.655840957072484	0.885174873706529	1
GO:0008494	translation activator activity	3/6090	14/18639	0.214285714285714	0.655840957072484	0.885174873706529	1
GO:0031404	chloride ion binding	3/6090	14/18639	0.214285714285714	0.655840957072484	0.885174873706529	1
GO:0032036	myosin heavy chain binding	3/6090	14/18639	0.214285714285714	0.655840957072484	0.885174873706529	1
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	3/6090	14/18639	0.214285714285714	0.655840957072484	0.885174873706529	1
GO:0098599	palmitoyl hydrolase activity	3/6090	14/18639	0.214285714285714	0.655840957072484	0.885174873706529	1
GO:0004970	glutamate-gated receptor activity	4/6090	18/18639	0.222222222222222	0.680131362889984	0.887790326770388	1
GO:0016854	racemase and epimerase activity	4/6090	18/18639	0.222222222222222	0.680131362889984	0.887790326770388	1
GO:0004177	aminopeptidase activity	10/6090	40/18639	0.25	0.765147783251232	0.887962275757	1
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/6090	10/18639	0.2	0.612118226600985	0.888058483766137	1
GO:0004935	adrenergic receptor activity	2/6090	10/18639	0.2	0.612118226600985	0.888058483766137	1
GO:0005031	tumor necrosis factor receptor activity	2/6090	10/18639	0.2	0.612118226600985	0.888058483766137	1
GO:0005337	nucleoside transmembrane transporter activity	2/6090	10/18639	0.2	0.612118226600985	0.888058483766137	1
GO:0005345	purine nucleobase transmembrane transporter activity	2/6090	10/18639	0.2	0.612118226600985	0.888058483766137	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/6090	10/18639	0.2	0.612118226600985	0.888058483766137	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/6090	10/18639	0.2	0.612118226600985	0.888058483766137	1
GO:0016868	intramolecular phosphotransferase activity	2/6090	10/18639	0.2	0.612118226600985	0.888058483766137	1
GO:0031996	thioesterase binding	2/6090	10/18639	0.2	0.612118226600985	0.888058483766137	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/6090	10/18639	0.2	0.612118226600985	0.888058483766137	1
GO:0047429	nucleoside triphosphate diphosphatase activity	2/6090	10/18639	0.2	0.612118226600985	0.888058483766137	1
GO:0140940	histone H2A methyltransferase activity	2/6090	10/18639	0.2	0.612118226600985	0.888058483766137	1
GO:1990259	histone H2AQ104 methyltransferase activity	2/6090	10/18639	0.2	0.612118226600985	0.888058483766137	1
GO:0140223	general transcription initiation factor activity	18/6090	68/18639	0.264705882352941	0.810156476383657	0.890830328667726	1
GO:0005243	gap junction channel activity	5/6090	22/18639	0.227272727272727	0.695588893864756	0.89259923862536	1
GO:0033691	sialic acid binding	5/6090	22/18639	0.227272727272727	0.695588893864756	0.89259923862536	1
GO:0140784	metal ion sensor activity	5/6090	22/18639	0.227272727272727	0.695588893864756	0.89259923862536	1
GO:0017171	serine hydrolase activity	57/6090	198/18639	0.287878787878788	0.881079265562024	0.894989865295476	1
GO:0005272	sodium channel activity	13/6090	51/18639	0.254901960784314	0.78015068096204	0.895526376046124	1
GO:0033218	amide binding	72/6090	247/18639	0.291497975708502	0.892156119742327	0.896496659199916	1
GO:0008198	ferrous iron binding	6/6090	26/18639	0.230769230769231	0.706290261462675	0.898274007770926	1
GO:0070006	metalloaminopeptidase activity	6/6090	26/18639	0.230769230769231	0.706290261462675	0.898274007770926	1
GO:0016209	antioxidant activity	23/6090	86/18639	0.267441860465116	0.818530186733875	0.90331840882159	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	36/6090	130/18639	0.276923076923077	0.84754831375521	0.906205320932434	1
GO:0015020	glucuronosyltransferase activity	8/6090	34/18639	0.235294117647059	0.720139090118806	0.910105028008668	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	8/6090	34/18639	0.235294117647059	0.720139090118806	0.910105028008668	1
GO:0005126	cytokine receptor binding	80/6090	275/18639	0.290909090909091	0.890353784146888	0.911053219092624	1
GO:0000774	adenyl-nucleotide exchange factor activity	3/6090	15/18639	0.2	0.612118226600985	0.912705237953114	1
GO:0004089	carbonate dehydratase activity	3/6090	15/18639	0.2	0.612118226600985	0.912705237953114	1
GO:0010181	FMN binding	3/6090	15/18639	0.2	0.612118226600985	0.912705237953114	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	3/6090	15/18639	0.2	0.612118226600985	0.912705237953114	1
GO:0140776	protein-containing complex destabilizing activity	3/6090	15/18639	0.2	0.612118226600985	0.912705237953114	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	5/6090	23/18639	0.217391304347826	0.665345898479332	0.914599686764153	1
GO:0005212	structural constituent of eye lens	5/6090	23/18639	0.217391304347826	0.665345898479332	0.914599686764153	1
GO:0008171	O-methyltransferase activity	5/6090	23/18639	0.217391304347826	0.665345898479332	0.914599686764153	1
GO:0004364	glutathione transferase activity	6/6090	27/18639	0.222222222222222	0.680131362889984	0.917999114464579	1
GO:0005104	fibroblast growth factor receptor binding	6/6090	27/18639	0.222222222222222	0.680131362889984	0.917999114464579	1
GO:0008395	steroid hydroxylase activity	6/6090	27/18639	0.222222222222222	0.680131362889984	0.917999114464579	1
GO:0015205	nucleobase transmembrane transporter activity	2/6090	11/18639	0.181818181818182	0.556471115091805	0.918399647971658	1
GO:0019203	carbohydrate phosphatase activity	2/6090	11/18639	0.181818181818182	0.556471115091805	0.918399647971658	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/6090	11/18639	0.181818181818182	0.556471115091805	0.918399647971658	1
GO:0022853	active monoatomic ion transmembrane transporter activity	32/6090	118/18639	0.271186440677966	0.829990815730149	0.919422493503167	1
GO:0005164	tumor necrosis factor receptor binding	7/6090	31/18639	0.225806451612903	0.691101223581758	0.92196020489543	1
GO:0016860	intramolecular oxidoreductase activity	13/6090	53/18639	0.245283018867925	0.75071103262385	0.924181949419657	1
GO:0017046	peptide hormone binding	13/6090	53/18639	0.245283018867925	0.75071103262385	0.924181949419657	1
GO:0004623	phospholipase A2 activity	8/6090	35/18639	0.228571428571429	0.699563687543983	0.926139818352322	1
GO:0005326	neurotransmitter transmembrane transporter activity	4/6090	20/18639	0.2	0.612118226600985	0.932080527468814	1
GO:0140664	ATP-dependent DNA damage sensor activity	4/6090	20/18639	0.2	0.612118226600985	0.932080527468814	1
GO:0019957	C-C chemokine binding	5/6090	24/18639	0.208333333333333	0.63762315270936	0.932526583715916	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	5/6090	24/18639	0.208333333333333	0.63762315270936	0.932526583715916	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	5/6090	24/18639	0.208333333333333	0.63762315270936	0.932526583715916	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	5/6090	24/18639	0.208333333333333	0.63762315270936	0.932526583715916	1
GO:0000062	fatty-acyl-CoA binding	3/6090	16/18639	0.1875	0.573860837438424	0.934088823435831	1
GO:0015378	sodium:chloride symporter activity	3/6090	16/18639	0.1875	0.573860837438424	0.934088823435831	1
GO:0016722	oxidoreductase activity, acting on metal ions	3/6090	16/18639	0.1875	0.573860837438424	0.934088823435831	1
GO:0022841	potassium ion leak channel activity	3/6090	16/18639	0.1875	0.573860837438424	0.934088823435831	1
GO:0005242	inward rectifier potassium channel activity	6/6090	28/18639	0.214285714285714	0.655840957072484	0.93429391862262	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	10/6090	43/18639	0.232558139534884	0.711765379768587	0.934473237332373	1
GO:0042910	xenobiotic transmembrane transporter activity	7/6090	32/18639	0.21875	0.669504310344828	0.936776697049642	1
GO:0008236	serine-type peptidase activity	54/6090	194/18639	0.278350515463918	0.851917119496217	0.93751720966909	1
GO:0004222	metalloendopeptidase activity	29/6090	110/18639	0.263636363636364	0.806883116883117	0.937603298425584	1
GO:0055106	ubiquitin-protein transferase regulator activity	8/6090	36/18639	0.222222222222222	0.680131362889984	0.9396307104107	1
GO:0003720	telomerase activity	2/6090	12/18639	0.166666666666667	0.510098522167488	0.940867224686869	1
GO:0005436	sodium:phosphate symporter activity	2/6090	12/18639	0.166666666666667	0.510098522167488	0.940867224686869	1
GO:0015132	prostaglandin transmembrane transporter activity	2/6090	12/18639	0.166666666666667	0.510098522167488	0.940867224686869	1
GO:0036009	protein-glutamine N-methyltransferase activity	2/6090	12/18639	0.166666666666667	0.510098522167488	0.940867224686869	1
GO:0097371	MDM2/MDM4 family protein binding	2/6090	12/18639	0.166666666666667	0.510098522167488	0.940867224686869	1
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/6090	12/18639	0.166666666666667	0.510098522167488	0.940867224686869	1
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/6090	12/18639	0.166666666666667	0.510098522167488	0.940867224686869	1
GO:0046943	carboxylic acid transmembrane transporter activity	52/6090	188/18639	0.276595744680851	0.846546483597107	0.941263513446229	1
GO:0001664	G protein-coupled receptor binding	85/6090	297/18639	0.286195286195286	0.8759267552371	0.94238234841821	1
GO:0005342	organic acid transmembrane transporter activity	52/6090	189/18639	0.275132275132275	0.842067401673313	0.94671558927205	1
GO:0008483	transaminase activity	5/6090	25/18639	0.2	0.612118226600985	0.947006778320627	1
GO:0015271	outward rectifier potassium channel activity	5/6090	25/18639	0.2	0.612118226600985	0.947006778320627	1
GO:0005248	voltage-gated sodium channel activity	4/6090	21/18639	0.19047619047619	0.582969739619986	0.947662141367858	1
GO:0070182	DNA polymerase binding	4/6090	21/18639	0.19047619047619	0.582969739619986	0.947662141367858	1
GO:1904047	S-adenosyl-L-methionine binding	4/6090	21/18639	0.19047619047619	0.582969739619986	0.947662141367858	1
GO:0009881	photoreceptor activity	3/6090	17/18639	0.176470588235294	0.540104317589105	0.950539426153597	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	3/6090	17/18639	0.176470588235294	0.540104317589105	0.950539426153597	1
GO:0016018	cyclosporin A binding	3/6090	17/18639	0.176470588235294	0.540104317589105	0.950539426153597	1
GO:0045125	bioactive lipid receptor activity	3/6090	17/18639	0.176470588235294	0.540104317589105	0.950539426153597	1
GO:0045236	CXCR chemokine receptor binding	3/6090	17/18639	0.176470588235294	0.540104317589105	0.950539426153597	1
GO:1901567	fatty acid derivative binding	3/6090	17/18639	0.176470588235294	0.540104317589105	0.950539426153597	1
GO:0016853	isomerase activity	49/6090	180/18639	0.272222222222222	0.83316091954023	0.951992935922785	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	22/6090	88/18639	0.25	0.765147783251232	0.953497725338442	1
GO:0030170	pyridoxal phosphate binding	13/6090	56/18639	0.232142857142857	0.710494370161858	0.954549149320732	1
GO:0051539	4 iron, 4 sulfur cluster binding	10/6090	45/18639	0.222222222222222	0.680131362889984	0.955230857728443	1
GO:0003964	RNA-directed DNA polymerase activity	2/6090	13/18639	0.153846153846154	0.47086017430845	0.957366496678086	1
GO:0005035	death receptor activity	2/6090	13/18639	0.153846153846154	0.47086017430845	0.957366496678086	1
GO:0005542	folic acid binding	2/6090	13/18639	0.153846153846154	0.47086017430845	0.957366496678086	1
GO:0009982	pseudouridine synthase activity	2/6090	13/18639	0.153846153846154	0.47086017430845	0.957366496678086	1
GO:0019104	DNA N-glycosylase activity	2/6090	13/18639	0.153846153846154	0.47086017430845	0.957366496678086	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/6090	13/18639	0.153846153846154	0.47086017430845	0.957366496678086	1
GO:0071714	icosanoid transmembrane transporter activity	2/6090	13/18639	0.153846153846154	0.47086017430845	0.957366496678086	1
GO:0071837	HMG box domain binding	2/6090	13/18639	0.153846153846154	0.47086017430845	0.957366496678086	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	7/6090	34/18639	0.205882352941176	0.630121703853955	0.959147815176791	1
GO:0061133	endopeptidase activator activity	4/6090	22/18639	0.181818181818182	0.556471115091805	0.959898341977302	1
GO:0070279	vitamin B6 binding	13/6090	57/18639	0.228070175438596	0.698029556650246	0.961971672566657	1
GO:0003746	translation elongation factor activity	3/6090	18/18639	0.166666666666667	0.510098522167488	0.963089246030239	1
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	3/6090	18/18639	0.166666666666667	0.510098522167488	0.963089246030239	1
GO:0015373	monoatomic anion:sodium symporter activity	3/6090	18/18639	0.166666666666667	0.510098522167488	0.963089246030239	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	3/6090	18/18639	0.166666666666667	0.510098522167488	0.963089246030239	1
GO:0015370	solute:sodium symporter activity	19/6090	79/18639	0.240506329113924	0.736091538317641	0.963558163050987	1
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	14/6090	61/18639	0.229508196721311	0.702430751837196	0.964117764402531	1
GO:0016229	steroid dehydrogenase activity	7/6090	35/18639	0.2	0.612118226600985	0.967399814382908	1
GO:0015079	potassium ion transmembrane transporter activity	42/6090	160/18639	0.2625	0.803405172413793	0.967890182643642	1
GO:0005344	oxygen carrier activity	2/6090	14/18639	0.142857142857143	0.437227304714989	0.969398433840013	1
GO:0008331	high voltage-gated calcium channel activity	2/6090	14/18639	0.142857142857143	0.437227304714989	0.969398433840013	1
GO:0016493	C-C chemokine receptor activity	4/6090	23/18639	0.173913043478261	0.532276718783465	0.969434900969544	1
GO:0005504	fatty acid binding	10/6090	47/18639	0.212765957446809	0.651189602767006	0.969930729206626	1
GO:0042277	peptide binding	68/6090	249/18639	0.273092369477912	0.835824084515401	0.971747047531747	1
GO:0008301	DNA binding, bending	3/6090	19/18639	0.157894736842105	0.483251231527094	0.972592595615415	1
GO:0034987	immunoglobulin receptor binding	3/6090	19/18639	0.157894736842105	0.483251231527094	0.972592595615415	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	6/6090	32/18639	0.1875	0.573860837438424	0.974315107556769	1
GO:0003954	NADH dehydrogenase activity	9/6090	44/18639	0.204545454545455	0.62603000447828	0.97480865783726	1
GO:0046906	tetrapyrrole binding	39/6090	152/18639	0.256578947368421	0.785283251231527	0.975624324471886	1
GO:0016846	carbon-sulfur lyase activity	2/6090	15/18639	0.133333333333333	0.40807881773399	0.978120463976458	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/6090	15/18639	0.133333333333333	0.40807881773399	0.978120463976458	1
GO:0031386	protein tag activity	2/6090	15/18639	0.133333333333333	0.40807881773399	0.978120463976458	1
GO:0034483	heparan sulfate sulfotransferase activity	2/6090	15/18639	0.133333333333333	0.40807881773399	0.978120463976458	1
GO:0141047	molecular tag activity	2/6090	15/18639	0.133333333333333	0.40807881773399	0.978120463976458	1
GO:0008237	metallopeptidase activity	48/6090	184/18639	0.260869565217391	0.798415078175198	0.978539403528632	1
GO:0022829	wide pore channel activity	7/6090	37/18639	0.189189189189189	0.579030754892824	0.979516031483439	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	3/6090	20/18639	0.15	0.459088669950739	0.979741784111874	1
GO:0015464	acetylcholine receptor activity	3/6090	20/18639	0.15	0.459088669950739	0.979741784111874	1
GO:0016408	C-acyltransferase activity	3/6090	20/18639	0.15	0.459088669950739	0.979741784111874	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	15/6090	68/18639	0.220588235294118	0.675130396986381	0.980171753011398	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	11/6090	53/18639	0.207547169811321	0.635217027604796	0.980672811209603	1
GO:0004955	prostaglandin receptor activity	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0004983	neuropeptide Y receptor activity	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0008519	ammonium channel activity	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0016783	sulfurtransferase activity	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0031720	haptoglobin binding	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0032052	bile acid binding	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0042166	acetylcholine binding	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0050308	sugar-phosphatase activity	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0051378	serotonin binding	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0141109	transporter activator activity	1/6090	10/18639	0.1	0.306059113300493	0.980885803192094	1
GO:0008083	growth factor activity	41/6090	162/18639	0.253086419753086	0.774594052180259	0.983409461737753	1
GO:0004252	serine-type endopeptidase activity	45/6090	176/18639	0.255681818181818	0.78253750559785	0.983701382750989	1
GO:0019825	oxygen binding	6/6090	34/18639	0.176470588235294	0.540104317589105	0.984382602361178	1
GO:0015125	bile acid transmembrane transporter activity	3/6090	21/18639	0.142857142857143	0.437227304714989	0.985088391235877	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	5/6090	30/18639	0.166666666666667	0.510098522167488	0.985328763470922	1
GO:0001637	G protein-coupled chemoattractant receptor activity	4/6090	26/18639	0.153846153846154	0.47086017430845	0.986837309822302	1
GO:0004950	chemokine receptor activity	4/6090	26/18639	0.153846153846154	0.47086017430845	0.986837309822302	1
GO:0008066	glutamate receptor activity	4/6090	26/18639	0.153846153846154	0.47086017430845	0.986837309822302	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/6090	11/18639	0.0909090909090909	0.278235557545902	0.987134418714137	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/6090	11/18639	0.0909090909090909	0.278235557545902	0.987134418714137	1
GO:0004954	prostanoid receptor activity	1/6090	11/18639	0.0909090909090909	0.278235557545902	0.987134418714137	1
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/6090	11/18639	0.0909090909090909	0.278235557545902	0.987134418714137	1
GO:0008199	ferric iron binding	1/6090	11/18639	0.0909090909090909	0.278235557545902	0.987134418714137	1
GO:0016594	glycine binding	1/6090	11/18639	0.0909090909090909	0.278235557545902	0.987134418714137	1
GO:0031731	CCR6 chemokine receptor binding	1/6090	11/18639	0.0909090909090909	0.278235557545902	0.987134418714137	1
GO:0042608	T cell receptor binding	1/6090	11/18639	0.0909090909090909	0.278235557545902	0.987134418714137	1
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/6090	11/18639	0.0909090909090909	0.278235557545902	0.987134418714137	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/6090	11/18639	0.0909090909090909	0.278235557545902	0.987134418714137	1
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/6090	11/18639	0.0909090909090909	0.278235557545902	0.987134418714137	1
GO:0140299	molecular sensor activity	15/6090	71/18639	0.211267605633803	0.646603760493998	0.988694928328004	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/6090	17/18639	0.117647058823529	0.360069545059403	0.98892686796418	1
GO:0004549	tRNA-specific ribonuclease activity	2/6090	17/18639	0.117647058823529	0.360069545059403	0.98892686796418	1
GO:0030169	low-density lipoprotein particle binding	2/6090	17/18639	0.117647058823529	0.360069545059403	0.98892686796418	1
GO:0008649	rRNA methyltransferase activity	3/6090	22/18639	0.136363636363636	0.417353336318854	0.989065767434599	1
GO:0044183	protein folding chaperone	16/6090	75/18639	0.213333333333333	0.652926108374384	0.98913752405532	1
GO:0008135	translation factor activity, RNA binding	18/6090	83/18639	0.216867469879518	0.663742655350466	0.990046490586891	1
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	7/6090	40/18639	0.175	0.535603448275862	0.990102878648342	1
GO:0004033	aldo-keto reductase (NADPH) activity	6/6090	36/18639	0.166666666666667	0.510098522167488	0.99065499884933	1
GO:0020037	heme binding	34/6090	142/18639	0.23943661971831	0.732817595226532	0.991133893063592	1
GO:0097677	STAT family protein binding	1/6090	12/18639	0.0833333333333333	0.255049261083744	0.991340527262071	1
GO:0030515	snoRNA binding	5/6090	32/18639	0.15625	0.47821736453202	0.991482769924367	1
GO:0071813	lipoprotein particle binding	5/6090	32/18639	0.15625	0.47821736453202	0.991482769924367	1
GO:0071814	protein-lipid complex binding	5/6090	32/18639	0.15625	0.47821736453202	0.991482769924367	1
GO:0046982	protein heterodimerization activity	100/6090	369/18639	0.2710027100271	0.829428491329248	0.991664973975862	1
GO:0180051	translation factor activity	18/6090	84/18639	0.214285714285714	0.655840957072484	0.991710047739458	1
GO:0140102	catalytic activity, acting on a rRNA	3/6090	23/18639	0.130434782608696	0.399207539087599	0.992010397404357	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/6090	18/18639	0.111111111111111	0.340065681444992	0.992156570705922	1
GO:0008137	NADH dehydrogenase (ubiquinone) activity	7/6090	41/18639	0.170731707317073	0.522539949537426	0.992290850897664	1
GO:0099094	ligand-gated monoatomic cation channel activity	32/6090	136/18639	0.235294117647059	0.720139090118806	0.992530872093791	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	11/6090	58/18639	0.189655172413793	0.580456939018176	0.993329305207401	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	8/6090	46/18639	0.173913043478261	0.532276718783465	0.993685070042577	1
GO:0004993	G protein-coupled serotonin receptor activity	1/6090	13/18639	0.0769230769230769	0.235430087154225	0.994171696477403	1
GO:0008035	high-density lipoprotein particle binding	1/6090	13/18639	0.0769230769230769	0.235430087154225	0.994171696477403	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/6090	24/18639	0.125	0.382573891625616	0.994180944973513	1
GO:0003743	translation initiation factor activity	9/6090	51/18639	0.176470588235294	0.540104317589105	0.994850690281093	1
GO:0016830	carbon-carbon lyase activity	9/6090	51/18639	0.176470588235294	0.540104317589105	0.994850690281093	1
GO:0016831	carboxy-lyase activity	5/6090	34/18639	0.147058823529412	0.450086931324254	0.995125744752101	1
GO:0016829	lyase activity	49/6090	200/18639	0.245	0.749844827586207	0.995483975209128	1
GO:0005537	D-mannose binding	3/6090	25/18639	0.12	0.367270935960591	0.995774534890522	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/6090	25/18639	0.12	0.367270935960591	0.995774534890522	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	9/6090	52/18639	0.173076923076923	0.529717696097006	0.995949240635888	1
GO:0043176	amine binding	1/6090	14/18639	0.0714285714285714	0.218613652357495	0.996077332064894	1
GO:1990825	sequence-specific mRNA binding	1/6090	14/18639	0.0714285714285714	0.218613652357495	0.996077332064894	1
GO:0001614	purinergic nucleotide receptor activity	2/6090	20/18639	0.1	0.306059113300493	0.996093373803366	1
GO:0016502	nucleotide receptor activity	2/6090	20/18639	0.1	0.306059113300493	0.996093373803366	1
GO:0042288	MHC class I protein binding	2/6090	20/18639	0.1	0.306059113300493	0.996093373803366	1
GO:0071855	neuropeptide receptor binding	6/6090	40/18639	0.15	0.459088669950739	0.996791586055498	1
GO:0019865	immunoglobulin binding	3/6090	26/18639	0.115384615384615	0.353145130731338	0.996940259899421	1
GO:0005267	potassium channel activity	27/6090	124/18639	0.217741935483871	0.666419037025266	0.997291429070431	1
GO:0004953	icosanoid receptor activity	1/6090	15/18639	0.0666666666666667	0.204039408866995	0.997359965499782	1
GO:0008020	G protein-coupled photoreceptor activity	1/6090	15/18639	0.0666666666666667	0.204039408866995	0.997359965499782	1
GO:0015250	water channel activity	1/6090	15/18639	0.0666666666666667	0.204039408866995	0.997359965499782	1
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/6090	15/18639	0.0666666666666667	0.204039408866995	0.997359965499782	1
GO:0042287	MHC protein binding	6/6090	41/18639	0.146341463414634	0.447891385317794	0.997563140653984	1
GO:0051082	unfolded protein binding	26/6090	121/18639	0.214876033057851	0.657647681472133	0.997618018163073	1
GO:0015252	proton channel activity	3/6090	27/18639	0.111111111111111	0.340065681444992	0.997790133325696	1
GO:0023026	MHC class II protein complex binding	3/6090	27/18639	0.111111111111111	0.340065681444992	0.997790133325696	1
GO:0022824	transmitter-gated monoatomic ion channel activity	11/6090	63/18639	0.174603174603175	0.534388927984987	0.997864463871486	1
GO:0022835	transmitter-gated channel activity	11/6090	63/18639	0.174603174603175	0.534388927984987	0.997864463871486	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	7/6090	46/18639	0.152173913043478	0.465742128935532	0.997893861903084	1
GO:0036002	pre-mRNA binding	10/6090	59/18639	0.169491525423729	0.518744259831343	0.997948141302021	1
GO:0022834	ligand-gated channel activity	44/6090	188/18639	0.234042553191489	0.716308563043706	0.997991636438198	1
GO:0015078	proton transmembrane transporter activity	43/6090	185/18639	0.232432432432432	0.711380641725469	0.998163002158257	1
GO:0051536	iron-sulfur cluster binding	14/6090	76/18639	0.184210526315789	0.563793103448276	0.998199283985397	1
GO:0042379	chemokine receptor binding	13/6090	72/18639	0.180555555555556	0.552606732348112	0.998219738188026	1
GO:0017070	U6 snRNA binding	1/6090	16/18639	0.0625	0.191286945812808	0.998223249977141	1
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/6090	16/18639	0.0625	0.191286945812808	0.998223249977141	1
GO:0050698	proteoglycan sulfotransferase activity	3/6090	28/18639	0.107142857142857	0.327920478536242	0.99840781212632	1
GO:0051537	2 iron, 2 sulfur cluster binding	3/6090	28/18639	0.107142857142857	0.327920478536242	0.99840781212632	1
GO:0015276	ligand-gated monoatomic ion channel activity	43/6090	186/18639	0.231182795698925	0.707556014619418	0.998418586312227	1
GO:0051540	metal cluster binding	14/6090	77/18639	0.181818181818182	0.556471115091805	0.998556111267763	1
GO:0031681	G-protein beta-subunit binding	2/6090	23/18639	0.0869565217391304	0.266138359391733	0.998647538262997	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	28/6090	132/18639	0.212121212121212	0.649216300940439	0.998713769931278	1
GO:0004497	monooxygenase activity	21/6090	106/18639	0.19811320754717	0.606343526350033	0.998887539388211	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	8/6090	53/18639	0.150943396226415	0.461976020076215	0.998938115580886	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	25/6090	122/18639	0.204918032786885	0.627170314140354	0.999002352520767	1
GO:0005216	monoatomic ion channel activity	117/6090	448/18639	0.261160714285714	0.79930616643209	0.999033176450217	1
GO:0017069	snRNA binding	8/6090	54/18639	0.148148148148148	0.453420908593322	0.999185615798333	1
GO:0005372	water transmembrane transporter activity	1/6090	18/18639	0.0555555555555556	0.170032840722496	0.999195315214541	1
GO:0032393	MHC class I receptor activity	1/6090	18/18639	0.0555555555555556	0.170032840722496	0.999195315214541	1
GO:0008009	chemokine activity	6/6090	45/18639	0.133333333333333	0.40807881773399	0.999210801213694	1
GO:0048020	CCR chemokine receptor binding	7/6090	50/18639	0.14	0.42848275862069	0.999290860601177	1
GO:0022843	voltage-gated monoatomic cation channel activity	30/6090	143/18639	0.20979020979021	0.642082055875159	0.999305049824879	1
GO:0005261	monoatomic cation channel activity	85/6090	341/18639	0.249266862170088	0.762903948109732	0.999324520886144	1
GO:0001530	lipopolysaccharide binding	5/6090	41/18639	0.121951219512195	0.373242821098162	0.999370246488292	1
GO:0008227	G protein-coupled amine receptor activity	5/6090	41/18639	0.121951219512195	0.373242821098162	0.999370246488292	1
GO:0005184	neuropeptide hormone activity	3/6090	31/18639	0.0967741935483871	0.296186238677896	0.999412230459324	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/6090	19/18639	0.0526315789473684	0.161083743842365	0.999458487457892	1
GO:0099589	serotonin receptor activity	1/6090	19/18639	0.0526315789473684	0.161083743842365	0.999458487457892	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	12/6090	73/18639	0.164383561643836	0.503110871178892	0.999465832081695	1
GO:0005249	voltage-gated potassium channel activity	18/6090	98/18639	0.183673469387755	0.562149391776415	0.999498758456088	1
GO:0022832	voltage-gated channel activity	38/6090	175/18639	0.217142857142857	0.664585503166784	0.999508174121606	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	8/6090	56/18639	0.142857142857143	0.437227304714989	0.999524383026478	1
GO:0023023	MHC protein complex binding	4/6090	37/18639	0.108108108108108	0.330874717081614	0.999537106727075	1
GO:0160041	neuropeptide activity	3/6090	32/18639	0.09375	0.286930418719212	0.999580008018338	1
GO:0005244	voltage-gated monoatomic ion channel activity	37/6090	173/18639	0.213872832369942	0.654577294342094	0.999633712465468	1
GO:0030627	pre-mRNA 5'-splice site binding	1/6090	20/18639	0.05	0.153029556650246	0.999635598702867	1
GO:0001846	opsonin binding	1/6090	21/18639	0.0476190476190476	0.145742434904996	0.999754788986961	1
GO:0140662	ATP-dependent protein folding chaperone	4/6090	40/18639	0.1	0.306059113300493	0.999823351882213	1
GO:0098960	postsynaptic neurotransmitter receptor activity	10/6090	69/18639	0.144927536231884	0.443563932319554	0.99983744337308	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	3/6090	36/18639	0.0833333333333333	0.255049261083744	0.999892333333712	1
GO:0030594	neurotransmitter receptor activity	16/6090	97/18639	0.164948453608247	0.504839774516276	0.999902079965641	1
GO:0008188	neuropeptide receptor activity	5/6090	48/18639	0.104166666666667	0.31881157635468	0.999927269281586	1
GO:0038187	pattern recognition receptor activity	5/6090	48/18639	0.104166666666667	0.31881157635468	0.999927269281586	1
GO:0140375	immune receptor activity	30/6090	156/18639	0.192307692307692	0.588575217885563	0.999940576862724	1
GO:0001848	complement binding	1/6090	25/18639	0.04	0.122423645320197	0.999949734871166	1
GO:0019843	rRNA binding	8/6090	65/18639	0.123076923076923	0.37668813944676	0.999961835828055	1
GO:0042923	neuropeptide binding	2/6090	33/18639	0.0606060606060606	0.185490371697268	0.999964021172969	1
GO:0016782	transferase activity, transferring sulphur-containing groups	9/6090	70/18639	0.128571428571429	0.393504574243491	0.999964561454995	1
GO:0022836	gated channel activity	71/6090	318/18639	0.223270440251572	0.683339529696068	0.999983934121328	1
GO:0008527	taste receptor activity	1/6090	28/18639	0.0357142857142857	0.109306826178747	0.999984691141523	1
GO:0008146	sulfotransferase activity	5/6090	53/18639	0.0943396226415094	0.288735012547635	0.999985226671735	1
GO:0005179	hormone activity	21/6090	132/18639	0.159090909090909	0.486912225705329	0.999996297181454	1
GO:0008528	G protein-coupled peptide receptor activity	17/6090	122/18639	0.139344262295082	0.426475813615441	0.9999994331326	1
GO:0042605	peptide antigen binding	2/6090	45/18639	0.0444444444444444	0.136026272577997	0.999999585713685	1
GO:0009055	electron transfer activity	15/6090	116/18639	0.129310344827586	0.39576609478512	0.999999755406854	1
GO:0001653	peptide receptor activity	17/6090	128/18639	0.1328125	0.406484759852217	0.999999884248527	1
GO:0005125	cytokine activity	41/6090	234/18639	0.175213675213675	0.536257420740179	0.999999947943204	1
GO:0030527	structural constituent of chromatin	10/6090	98/18639	0.102040816326531	0.312305217653564	0.999999959993744	1
GO:0003730	mRNA 3'-UTR binding	34/6090	262/18639	0.129770992366412	0.397175948557891	0.999999999999962	1
GO:0003735	structural constituent of ribosome	3/6090	175/18639	0.0171428571428571	0.0524672765657987	1	1
GO:0003823	antigen binding	10/6090	174/18639	0.0574712643678161	0.17589604212672	1	1
GO:0004984	olfactory receptor activity	7/6090	419/18639	0.0167064439140811	0.0511315941074809	1	1
GO:0005549	odorant binding	1/6090	111/18639	0.00900900900900901	0.0275728930901345	1	1
GO:0030371	translation repressor activity	16/6090	329/18639	0.0486322188449848	0.148843337775316	1	1
GO:0045182	translation regulator activity	25/6090	356/18639	0.0702247191011236	0.214929152598661	1	1