ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	69/2881	175/18639	0.394285714285714	2.5508821341796	1.14853143334931e-14	1.46093198322033e-11
GO:0003712	transcription coregulator activity	131/2881	495/18639	0.264646464646465	1.71216433687798	1.23794466218495e-10	6.85941576987089e-08
GO:0019787	ubiquitin-like protein transferase activity	127/2881	479/18639	0.265135699373695	1.71532950386196	2.09294225252237e-10	6.85941576987089e-08
GO:0016755	aminoacyltransferase activity	130/2881	496/18639	0.262096774193548	1.69566878659963	2.89532764794537e-10	6.85941576987089e-08
GO:0004812	aminoacyl-tRNA ligase activity	24/2881	41/18639	0.585365853658537	3.7870996689835	3.23557347635419e-10	6.85941576987089e-08
GO:0016875	ligase activity, forming carbon-oxygen bonds	24/2881	41/18639	0.585365853658537	3.7870996689835	3.23557347635419e-10	6.85941576987089e-08
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	32/2881	68/18639	0.470588235294118	3.04453110643772	7.68034978351673e-10	1.39562927494761e-07
GO:0004842	ubiquitin-protein transferase activity	115/2881	449/18639	0.256124721603563	1.65703182435572	1.26455719690207e-08	1.96214443036175e-06
GO:0106310	protein serine kinase activity	97/2881	361/18639	0.268698060941828	1.7383766601509	1.3883097384635e-08	1.96214443036175e-06
GO:0019902	phosphatase binding	60/2881	190/18639	0.315789473684211	2.04304061089899	1.77381729134321e-08	2.25629559458856e-06
GO:0004674	protein serine/threonine kinase activity	111/2881	433/18639	0.25635103926097	1.65849601554503	2.14758303467869e-08	2.4833869273739e-06
GO:0003713	transcription coactivator activity	73/2881	256/18639	0.28515625	1.84485503080528	6.54924051947285e-08	6.94219495064122e-06
GO:0030695	GTPase regulator activity	120/2881	489/18639	0.245398773006135	1.58763892053501	8.14176237539099e-08	7.96640133961334e-06
GO:0060589	nucleoside-triphosphatase regulator activity	120/2881	490/18639	0.244897959183673	1.58439884110534	9.17131749957798e-08	8.33279704247371e-06
GO:0016874	ligase activity	53/2881	167/18639	0.317365269461078	2.05323542432663	9.83236226570908e-08	8.3378432013213e-06
GO:0031491	nucleosome binding	30/2881	74/18639	0.405405405405405	2.62282240588384	1.71462189266594e-07	1.36312440466942e-05
GO:0005085	guanyl-nucleotide exchange factor activity	66/2881	230/18639	0.28695652173913	1.85650212033865	2.1306904811422e-07	1.59425781883111e-05
GO:0015078	proton transmembrane transporter activity	56/2881	185/18639	0.302702702702703	1.95837406305994	2.57095187481218e-07	1.81680599153394e-05
GO:0008137	NADH dehydrogenase (ubiquinone) activity	20/2881	41/18639	0.48780487804878	3.15591639081958	5.6356592465634e-07	3.77292555875192e-05
GO:0070063	RNA polymerase binding	25/2881	59/18639	0.423728813559322	2.74136805134752	6.67060784171396e-07	4.24250658733008e-05
GO:0031492	nucleosomal DNA binding	20/2881	42/18639	0.476190476190476	3.0807755243715	9.19777749719692e-07	5.57122522687357e-05
GO:0022853	active monoatomic ion transmembrane transporter activity	39/2881	118/18639	0.330508474576271	2.13826708005107	1.50008412641267e-06	8.6732136763496e-05
GO:0035403	histone H3T6 kinase activity	67/2881	247/18639	0.271255060728745	1.75491949910555	1.60845557967093e-06	8.89545868409315e-05
GO:0003954	NADH dehydrogenase activity	20/2881	44/18639	0.454545454545455	2.9407402732637	2.30460316746756e-06	0.00012214396787578
GO:0032182	ubiquitin-like protein binding	39/2881	120/18639	0.325	2.10262929538355	2.40137283975831e-06	0.000122181850086903
GO:0009055	electron transfer activity	38/2881	116/18639	0.327586206896552	2.11936109349005	2.59354782451723e-06	0.000123143293012807
GO:0045309	protein phosphorylated amino acid binding	24/2881	59/18639	0.406779661016949	2.63171332929362	2.67850131601338e-06	0.000123143293012807
GO:0061650	ubiquitin-like protein conjugating enzyme activity	19/2881	41/18639	0.463414634146341	2.9981205712786	2.87832047480598e-06	0.000123143293012807
GO:0140857	histone H3T45 kinase activity	66/2881	246/18639	0.268292682926829	1.73575401495077	2.8882616320337e-06	0.000123143293012807
GO:0019208	phosphatase regulator activity	38/2881	117/18639	0.324786324786325	2.10124689610979	3.2742610302723e-06	0.000123143293012807
GO:0043130	ubiquitin binding	34/2881	100/18639	0.34	2.19967372440125	3.38789513521909e-06	0.000123143293012807
GO:0019903	protein phosphatase binding	44/2881	144/18639	0.305555555555556	1.97683096147171	3.60880655646221e-06	0.000123143293012807
GO:0044389	ubiquitin-like protein ligase binding	81/2881	322/18639	0.251552795031056	1.62745315743973	3.68899173650116e-06	0.000123143293012807
GO:0031625	ubiquitin protein ligase binding	77/2881	302/18639	0.254966887417219	1.64954106718832	3.71937777896527e-06	0.000123143293012807
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	65/2881	243/18639	0.267489711934156	1.73055909085066	3.81644215971414e-06	0.000123143293012807
GO:0051219	phosphoprotein binding	32/2881	93/18639	0.344086021505376	2.22610876599747	4.87971308609697e-06	0.000123143293012807
GO:0004676	3-phosphoinositide-dependent protein kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0004711	ribosomal protein S6 kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0035175	histone H3S10 kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0035979	histone H2AXS139 kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0044022	histone H3S28 kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0044023	histone H4S1 kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0044024	histone H2AS1 kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0044025	histone H2BS14 kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0072354	histone H3T3 kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0072371	histone H2AS121 kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0072518	Rho-dependent protein serine/threonine kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0140823	histone H2BS36 kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0140855	histone H3S57 kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0140995	histone H2A kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0140997	histone H4 kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0140998	histone H2B kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:1990244	histone H2AT120 kinase activity	65/2881	245/18639	0.26530612244898	1.71643207786412	5.1309705422003e-06	0.000123143293012807
GO:0004677	DNA-dependent protein kinase activity	65/2881	246/18639	0.264227642276423	1.70945471169394	5.93636324474634e-06	0.00013983433420958
GO:0019888	protein phosphatase regulator activity	35/2881	107/18639	0.327102803738318	2.11623365459164	6.58604077895122e-06	0.000152317161287744
GO:0140297	DNA-binding transcription factor binding	112/2881	488/18639	0.229508196721311	1.48483279371348	6.81047458824503e-06	0.000153048451376041
GO:0035402	histone H3T11 kinase activity	65/2881	247/18639	0.263157894736842	1.70253384241583	6.85830324562448e-06	0.000153048451376041
GO:0004679	AMP-activated protein kinase activity	65/2881	248/18639	0.262096774193548	1.69566878659963	7.91214524364761e-06	0.00017352153017103
GO:0045296	cadherin binding	82/2881	334/18639	0.245508982035928	1.58835193202626	8.69886588632184e-06	0.000187541650972905
GO:0140996	histone H3 kinase activity	86/2881	357/18639	0.240896358543417	1.55850997115264	1.16163539088964e-05	0.000246266702868603
GO:0016922	nuclear receptor binding	41/2881	137/18639	0.299270072992701	1.93616622371085	1.33676869054418e-05	0.000278749143339704
GO:0001098	basal transcription machinery binding	23/2881	60/18639	0.383333333333333	2.48002429711906	1.3936067431673e-05	0.000281375837668065
GO:0001099	basal RNA polymerase II transcription machinery binding	23/2881	60/18639	0.383333333333333	2.48002429711906	1.3936067431673e-05	0.000281375837668065
GO:0035173	histone kinase activity	86/2881	360/18639	0.238888888888889	1.5455223880597	1.62763142812129e-05	0.000323491746339106
GO:0140098	catalytic activity, acting on RNA	91/2881	387/18639	0.235142118863049	1.52128217753848	1.81019303908294e-05	0.000354240853186692
GO:0061659	ubiquitin-like protein ligase activity	88/2881	372/18639	0.236559139784946	1.53044977662326	1.94161077072365e-05	0.000374201348539466
GO:0061631	ubiquitin conjugating enzyme activity	16/2881	35/18639	0.457142857142857	2.95754450339664	2.16774402163911e-05	0.000411547820227604
GO:0034450	ubiquitin-ubiquitin ligase activity	10/2881	16/18639	0.625	4.04351787573759	2.49514919395531e-05	0.00046673967275164
GO:0141003	histone H2AX kinase activity	84/2881	354/18639	0.23728813559322	1.53516610875461	2.63677380894109e-05	0.000486083519561314
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	83/2881	349/18639	0.237822349570201	1.53862227477923	2.69414373179855e-05	0.000489564403835394
GO:0000993	RNA polymerase II complex binding	16/2881	36/18639	0.444444444444444	2.8753904894134	3.34382341169169e-05	0.000599062447841102
GO:0015399	primary active transmembrane transporter activity	46/2881	166/18639	0.27710843373494	1.7927886485198	3.67137776535233e-05	0.000648610071878912
GO:0051020	GTPase binding	75/2881	315/18639	0.238095238095238	1.54038776218575	6.1727684555902e-05	0.00107558376376859
GO:0061630	ubiquitin protein ligase activity	82/2881	353/18639	0.232294617563739	1.50285990169057	7.18114018006036e-05	0.00123437977149146
GO:0043175	RNA polymerase core enzyme binding	17/2881	42/18639	0.404761904761905	2.61865919571577	8.16092365777996e-05	0.00138409265235948
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	21/2881	58/18639	0.362068965517241	2.34245173491005	8.69620280294429e-05	0.00145546973228225
GO:0003725	double-stranded RNA binding	25/2881	75/18639	0.333333333333333	2.15654286706005	9.3100047754832e-05	0.00152594979116035
GO:0035591	signaling adaptor activity	37/2881	129/18639	0.286821705426357	1.85562990886562	9.35723928541723e-05	0.00152594979116035
GO:0055105	ubiquitin-protein transferase inhibitor activity	9/2881	15/18639	0.6	3.88177716070809	0.000102188451979421	0.00164536342933954
GO:0140101	catalytic activity, acting on a tRNA	39/2881	139/18639	0.280575539568345	1.81521953558292	0.000103652894206208	0.0016480810178787
GO:0035091	phosphatidylinositol binding	68/2881	284/18639	0.23943661971831	1.54906600309947	0.000110981727073498	0.00174282415848752
GO:0055106	ubiquitin-protein transferase regulator activity	15/2881	36/18639	0.416666666666667	2.69567858382506	0.00014414985274306	0.00223608064255087
GO:0030331	nuclear estrogen receptor binding	16/2881	40/18639	0.4	2.58785144047206	0.000155309340702438	0.00238016242618676
GO:0050815	phosphoserine residue binding	7/2881	10/18639	0.7	4.5287400208261	0.000162907011392377	0.00246687760108456
GO:0031490	chromatin DNA binding	36/2881	128/18639	0.28125	1.81958304408192	0.000178064877309181	0.00266468851690915
GO:0017124	SH3 domain binding	33/2881	115/18639	0.28695652173913	1.85650212033865	0.000215931220205689	0.00319377339653066
GO:0140030	modification-dependent protein binding	45/2881	173/18639	0.260115606936416	1.68285137024917	0.000222233378805716	0.00324920526253875
GO:1990948	ubiquitin ligase inhibitor activity	7/2881	11/18639	0.636363636363636	4.11703638256918	0.000387981444410986	0.00560809542375879
GO:0003743	translation initiation factor activity	18/2881	51/18639	0.352941176470588	2.28339832982829	0.000392712457797663	0.00561269939683851
GO:0140566	histone reader activity	14/2881	35/18639	0.4	2.58785144047206	0.000397357145836829	0.00561598099449384
GO:0005096	GTPase activator activity	63/2881	271/18639	0.232472324723247	1.50400960101236	0.000455786298529327	0.00637099089812423
GO:0003714	transcription corepressor activity	50/2881	204/18639	0.245098039215686	1.58569328460298	0.000477580641718211	0.00660307148114744
GO:0072542	protein phosphatase activator activity	10/2881	21/18639	0.476190476190476	3.0807755243715	0.000521506072783523	0.00713285725355528
GO:0019211	phosphatase activator activity	11/2881	25/18639	0.44	2.84663658451926	0.000637526051872222	0.00854026073803598
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	9/2881	18/18639	0.5	3.23481430059007	0.000637833938768411	0.00854026073803598
GO:0001222	transcription corepressor binding	17/2881	49/18639	0.346938775510204	2.24456502489923	0.000708589784163314	0.00938881464016391
GO:0004129	cytochrome-c oxidase activity	8/2881	15/18639	0.533333333333333	3.45046858729608	0.00074592323861572	0.00958398342948682
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	8/2881	15/18639	0.533333333333333	3.45046858729608	0.00074592323861572	0.00958398342948682
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	8/2881	15/18639	0.533333333333333	3.45046858729608	0.00074592323861572	0.00958398342948682
GO:0071889	14-3-3 protein binding	13/2881	33/18639	0.393939393939394	2.54864157016188	0.000757368436278954	0.00963372650946829
GO:0019207	kinase regulator activity	65/2881	287/18639	0.226480836236934	1.46524689573766	0.000782246647686739	0.00985166075106468
GO:0140463	chromatin-protein adaptor activity	18/2881	54/18639	0.333333333333333	2.15654286706005	0.000859274435417279	0.0107156576652037
GO:0043548	phosphatidylinositol 3-kinase binding	11/2881	26/18639	0.423076923076923	2.73715056203775	0.000951770644431646	0.0117539054341462
GO:0051540	metal cluster binding	23/2881	77/18639	0.298701298701299	1.93248646528758	0.00101649390319721	0.0124185853437223
GO:0051721	protein phosphatase 2A binding	12/2881	30/18639	0.4	2.58785144047206	0.00102511907318463	0.0124185853437223
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	8/2881	16/18639	0.5	3.23481430059007	0.00129035336234362	0.0153395278215054
GO:0016675	oxidoreductase activity, acting on a heme group of donors	8/2881	16/18639	0.5	3.23481430059007	0.00129035336234362	0.0153395278215054
GO:0005543	phospholipid binding	102/2881	497/18639	0.20523138832998	1.32777085979955	0.00134491386377105	0.0157224476305683
GO:0048156	tau protein binding	15/2881	43/18639	0.348837209302326	2.25684718645819	0.00134728521362574	0.0157224476305683
GO:0043021	ribonucleoprotein complex binding	43/2881	177/18639	0.242937853107345	1.57171768277258	0.00137675000177539	0.0159202363841663
GO:0019783	ubiquitin-like protein peptidase activity	33/2881	127/18639	0.259842519685039	1.68108459715705	0.00146334375763137	0.0166646852405568
GO:0031267	small GTPase binding	63/2881	283/18639	0.222614840989399	1.44023534231219	0.00146733077589808	0.0166646852405568
GO:0030159	signaling receptor complex adaptor activity	17/2881	52/18639	0.326923076923077	2.11507088884736	0.00151045699726528	0.017002666376296
GO:0070513	death domain binding	6/2881	10/18639	0.6	3.88177716070809	0.00162131105059365	0.0180904180382028
GO:0019003	GDP binding	22/2881	75/18639	0.293333333333333	1.89775772301284	0.00167994654024014	0.0185158272086388
GO:0042393	histone binding	56/2881	247/18639	0.226720647773279	1.4667983873121	0.0016885502800331	0.0185158272086388
GO:0061791	GTPase motor activity	14/2881	40/18639	0.35	2.26437001041305	0.0018615645331499	0.0200670346285311
GO:1990606	membrane scission GTPase motor activity	14/2881	40/18639	0.35	2.26437001041305	0.0018615645331499	0.0200670346285311
GO:0046966	nuclear thyroid hormone receptor binding	11/2881	28/18639	0.392857142857143	2.54163980760649	0.0019638747160427	0.0208461846061589
GO:0019210	kinase inhibitor activity	25/2881	90/18639	0.277777777777778	1.79711905588337	0.00196894585262899	0.0208461846061589
GO:0140142	nucleocytoplasmic carrier activity	12/2881	32/18639	0.375	2.42611072544255	0.00198300969917078	0.0208461846061589
GO:0051536	iron-sulfur cluster binding	22/2881	76/18639	0.289473684210526	1.87278722665741	0.00202504723673598	0.0211136072551489
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	8/2881	17/18639	0.470588235294118	3.04453110643772	0.00210891339372315	0.0218092507058198
GO:0051539	4 iron, 4 sulfur cluster binding	15/2881	45/18639	0.333333333333333	2.15654286706005	0.00226278980463923	0.0232118438024283
GO:0009931	calcium-dependent protein serine/threonine kinase activity	9/2881	21/18639	0.428571428571429	2.77269797193435	0.00248448174329505	0.0252820862197704
GO:0017025	TBP-class protein binding	10/2881	25/18639	0.4	2.58785144047206	0.00267491680279563	0.0270039220091749
GO:0030276	clathrin binding	15/2881	46/18639	0.326086956521739	2.10966150038483	0.00288520689242248	0.0288975052532394
GO:0008135	translation factor activity, RNA binding	23/2881	83/18639	0.27710843373494	1.7927886485198	0.00301950678029978	0.030006348629229
GO:0050786	RAGE receptor binding	6/2881	11/18639	0.545454545454545	3.52888832791644	0.00310130657801285	0.0303450920556335
GO:0070990	snRNP binding	6/2881	11/18639	0.545454545454545	3.52888832791644	0.00310130657801285	0.0303450920556335
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	8/2881	18/18639	0.444444444444444	2.8753904894134	0.00328577695768694	0.0319046434364717
GO:0180051	translation factor activity	23/2881	84/18639	0.273809523809524	1.77144592651361	0.0035615134499495	0.0341616505225233
GO:0052866	phosphatidylinositol phosphate phosphatase activity	12/2881	34/18639	0.352941176470588	2.28339832982829	0.00357193358450911	0.0341616505225233
GO:0001784	phosphotyrosine residue binding	15/2881	47/18639	0.319148936170213	2.06477508548303	0.0036420150037078	0.0345719633187785
GO:0052742	phosphatidylinositol kinase activity	10/2881	26/18639	0.384615384615385	2.48831869276159	0.00375188315177311	0.0353510768078178
GO:0031386	protein tag activity	7/2881	15/18639	0.466666666666667	3.01916001388407	0.00427392136815933	0.0396819560605742
GO:0141047	molecular tag activity	7/2881	15/18639	0.466666666666667	3.01916001388407	0.00427392136815933	0.0396819560605742
GO:0010485	histone H4 acetyltransferase activity	12/2881	35/18639	0.342857142857143	2.21815837754748	0.00468290085793456	0.043164129647049
GO:0003697	single-stranded DNA binding	30/2881	121/18639	0.247933884297521	1.60404014905293	0.00494866249674199	0.0452856021284591
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	10/2881	27/18639	0.37037037037037	2.39615874117783	0.00514494401342798	0.0465617038946325
GO:0044013	histone H2B acetyltransferase activity	9/2881	23/18639	0.391304347826087	2.5315938004618	0.00516132095058426	0.0465617038946325
GO:0035197	siRNA binding	6/2881	12/18639	0.5	3.23481430059007	0.0053958637408661	0.047996773974697
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	6/2881	12/18639	0.5	3.23481430059007	0.0053958637408661	0.047996773974697
GO:0003925	G protein activity	16/2881	54/18639	0.296296296296296	1.91692699294227	0.00614809593788558	0.054308180784656
GO:0016791	phosphatase activity	58/2881	273/18639	0.212454212454212	1.37449984933498	0.00638483794104903	0.0560104404207888
GO:0022884	macromolecule transmembrane transporter activity	11/2881	32/18639	0.34375	2.22393483165568	0.00652367808715053	0.0564326524187399
GO:0031593	polyubiquitin modification-dependent protein binding	17/2881	59/18639	0.288135593220339	1.86413027491631	0.00656551362379689	0.0564326524187399
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	7/2881	16/18639	0.4375	2.83046251301631	0.00659447426157153	0.0564326524187399
GO:0016651	oxidoreductase activity, acting on NAD(P)H	23/2881	88/18639	0.261363636363636	1.69092565712663	0.00661042862452221	0.0564326524187399
GO:0000287	magnesium ion binding	50/2881	230/18639	0.217391304347826	1.40644100025655	0.0068715271958294	0.0582273140523133
GO:0036408	histone H3K14 acetyltransferase activity	10/2881	28/18639	0.357142857142857	2.31058164327862	0.00691220473419757	0.0582273140523133
GO:0140318	protein transporter activity	13/2881	41/18639	0.317073170731707	2.05134565403273	0.00699794964954835	0.0585617891725362
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	8/2881	20/18639	0.4	2.58785144047206	0.00709524424757743	0.0586048745644058
GO:0061608	nuclear import signal receptor activity	8/2881	20/18639	0.4	2.58785144047206	0.00709524424757743	0.0586048745644058
GO:0004860	protein kinase inhibitor activity	22/2881	84/18639	0.261904761904762	1.69442653840432	0.00759327399251052	0.0622937055479391
GO:0003727	single-stranded RNA binding	23/2881	89/18639	0.258426966292135	1.67192649243981	0.00763979407663404	0.0622937055479391
GO:0001221	transcription coregulator binding	28/2881	115/18639	0.243478260869565	1.57521392028734	0.00837803895427368	0.0678781245212492
GO:0005048	signal sequence binding	15/2881	51/18639	0.294117647058824	1.90283194152357	0.00844616053781733	0.067996938000656
GO:0031994	insulin-like growth factor I binding	6/2881	13/18639	0.461538461538462	2.98598243131391	0.00872226683584474	0.0694016732079238
GO:0004402	histone acetyltransferase activity	13/2881	42/18639	0.30952380952381	2.00250409084147	0.00872977021483319	0.0694016732079238
GO:0019887	protein kinase regulator activity	54/2881	255/18639	0.211764705882353	1.37003899789697	0.00882182992379095	0.0696979357954167
GO:0010484	histone H3 acetyltransferase activity	10/2881	29/18639	0.344827586206897	2.23090641420005	0.00911482724905886	0.0715682732148326
GO:0061733	protein-lysine-acetyltransferase activity	14/2881	47/18639	0.297872340425532	1.92712341311749	0.00955436689544784	0.0738540449668519
GO:0004709	MAP kinase kinase kinase activity	9/2881	25/18639	0.36	2.32906629642485	0.0096549487038635	0.0738540449668519
GO:0008139	nuclear localization sequence binding	9/2881	25/18639	0.36	2.32906629642485	0.0096549487038635	0.0738540449668519
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	12/2881	38/18639	0.315789473684211	2.04304061089899	0.0097308467979154	0.0738540449668519
GO:0042162	telomeric DNA binding	12/2881	38/18639	0.315789473684211	2.04304061089899	0.0097308467979154	0.0738540449668519
GO:0042578	phosphoric ester hydrolase activity	73/2881	363/18639	0.201101928374656	1.30105478756515	0.00975430782581062	0.0738540449668519
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	8/2881	21/18639	0.380952380952381	2.4646204194972	0.00993263655790507	0.0738848754482763
GO:0035613	RNA stem-loop binding	8/2881	21/18639	0.380952380952381	2.4646204194972	0.00993263655790507	0.0738848754482763
GO:0051010	microtubule plus-end binding	8/2881	21/18639	0.380952380952381	2.4646204194972	0.00993263655790507	0.0738848754482763
GO:0017022	myosin binding	20/2881	76/18639	0.263157894736842	1.70253384241583	0.0100328353701764	0.0741963173887465
GO:0008641	ubiquitin-like modifier activating enzyme activity	5/2881	10/18639	0.5	3.23481430059007	0.0112078328448538	0.0819331228658279
GO:0015924	mannosyl-oligosaccharide mannosidase activity	5/2881	10/18639	0.5	3.23481430059007	0.0112078328448538	0.0819331228658279
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	30/2881	128/18639	0.234375	1.5163192034016	0.0113524449351022	0.0825160568997141
GO:0043995	histone H4K5 acetyltransferase activity	10/2881	30/18639	0.333333333333333	2.15654286706005	0.011815915903225	0.0844373316230464
GO:0043996	histone H4K8 acetyltransferase activity	10/2881	30/18639	0.333333333333333	2.15654286706005	0.011815915903225	0.0844373316230464
GO:0043997	histone H4K12 acetyltransferase activity	10/2881	30/18639	0.333333333333333	2.15654286706005	0.011815915903225	0.0844373316230464
GO:0016776	phosphotransferase activity, phosphate group as acceptor	12/2881	39/18639	0.307692307692308	1.99065495420928	0.0121218760693797	0.0854227241967846
GO:0001046	core promoter sequence-specific DNA binding	13/2881	44/18639	0.295454545454545	1.91148117762141	0.0131861554815432	0.0854227241967846
GO:0016248	channel inhibitor activity	13/2881	44/18639	0.295454545454545	1.91148117762141	0.0131861554815432	0.0854227241967846
GO:0032934	sterol binding	18/2881	68/18639	0.264705882352941	1.71254874737121	0.0132835126008344	0.0854227241967846
GO:1990841	promoter-specific chromatin binding	18/2881	68/18639	0.264705882352941	1.71254874737121	0.0132835126008344	0.0854227241967846
GO:0004197	cysteine-type endopeptidase activity	22/2881	88/18639	0.25	1.61740715029504	0.0132896026371584	0.0854227241967846
GO:0071933	Arp2/3 complex binding	6/2881	14/18639	0.428571428571429	2.77269797193435	0.0132933252819491	0.0854227241967846
GO:0032931	histone H3K56 acetyltransferase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0034062	5'-3' RNA polymerase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0043992	histone H3K9 acetyltransferase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0043993	histone H3K18 acetyltransferase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0043994	histone H3K23 acetyltransferase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0043999	histone H2AK5 acetyltransferase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0044012	histone H2AK9 acetyltransferase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0044014	histone H2BK5 acetyltransferase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0044015	histone H2BK12 acetyltransferase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0044016	histone H3K4 acetyltransferase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0044017	histone H3K27 acetyltransferase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0044018	histone H3K36 acetyltransferase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0046972	histone H4K16 acetyltransferase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0050321	tau-protein kinase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0097747	RNA polymerase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0140908	histone H3K122 acetyltransferase activity	8/2881	22/18639	0.363636363636364	2.35259221861096	0.0135319551146332	0.0854227241967846
GO:0000175	3'-5'-RNA exonuclease activity	11/2881	35/18639	0.314285714285714	2.03331184608519	0.0135655584023196	0.0854227241967846
GO:0004706	JUN kinase kinase kinase activity	7/2881	18/18639	0.388888888888889	2.51596667823672	0.0138380149944881	0.0854463838494604
GO:0008525	phosphatidylcholine transporter activity	7/2881	18/18639	0.388888888888889	2.51596667823672	0.0138380149944881	0.0854463838494604
GO:0070064	proline-rich region binding	7/2881	18/18639	0.388888888888889	2.51596667823672	0.0138380149944881	0.0854463838494604
GO:1990381	ubiquitin-specific protease binding	7/2881	18/18639	0.388888888888889	2.51596667823672	0.0138380149944881	0.0854463838494604
GO:0004532	RNA exonuclease activity	12/2881	40/18639	0.3	1.94088858035404	0.0149385388522268	0.0917962387441183
GO:0004715	non-membrane spanning protein tyrosine kinase activity	13/2881	45/18639	0.288888888888889	1.86900381811871	0.0159838627850262	0.0972797773327912
GO:0141110	transporter inhibitor activity	13/2881	45/18639	0.288888888888889	1.86900381811871	0.0159838627850262	0.0972797773327912
GO:0003924	GTPase activity	66/2881	331/18639	0.199395770392749	1.29001657908728	0.0160830673458168	0.097417436494662
GO:0008320	protein transmembrane transporter activity	9/2881	27/18639	0.333333333333333	2.15654286706005	0.0165976795757413	0.0995860774544476
GO:0015252	proton channel activity	9/2881	27/18639	0.333333333333333	2.15654286706005	0.0165976795757413	0.0995860774544476
GO:0044390	ubiquitin-like protein conjugating enzyme binding	11/2881	36/18639	0.305555555555556	1.97683096147171	0.0168709917969377	0.100750711576078
GO:0004721	phosphoprotein phosphatase activity	38/2881	175/18639	0.217142857142857	1.4048336391134	0.0170178890350609	0.101153060058867
GO:0000049	tRNA binding	20/2881	80/18639	0.25	1.61740715029504	0.0176743295780743	0.103113896949117
GO:0002162	dystroglycan binding	5/2881	11/18639	0.454545454545455	2.9407402732637	0.0179632714005546	0.103113896949117
GO:0008526	phosphatidylinositol transfer activity	5/2881	11/18639	0.454545454545455	2.9407402732637	0.0179632714005546	0.103113896949117
GO:0019107	myristoyltransferase activity	5/2881	11/18639	0.454545454545455	2.9407402732637	0.0179632714005546	0.103113896949117
GO:0032050	clathrin heavy chain binding	5/2881	11/18639	0.454545454545455	2.9407402732637	0.0179632714005546	0.103113896949117
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	5/2881	11/18639	0.454545454545455	2.9407402732637	0.0179632714005546	0.103113896949117
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	8/2881	23/18639	0.347826086956522	2.25030560041049	0.0179962933354592	0.103113896949117
GO:0070577	lysine-acetylated histone binding	8/2881	23/18639	0.347826086956522	2.25030560041049	0.0179962933354592	0.103113896949117
GO:0000149	SNARE binding	25/2881	106/18639	0.235849056603774	1.52585580216513	0.0181385573728812	0.103462981965493
GO:0015631	tubulin binding	75/2881	385/18639	0.194805194805195	1.26031725997016	0.0184885197383888	0.104988379942993
GO:0005520	insulin-like growth factor binding	7/2881	19/18639	0.368421052631579	2.38354737938216	0.0190434400815697	0.107101288977905
GO:0050145	nucleoside monophosphate kinase activity	7/2881	19/18639	0.368421052631579	2.38354737938216	0.0190434400815697	0.107101288977905
GO:1990782	protein tyrosine kinase binding	27/2881	117/18639	0.230769230769231	1.49299121565696	0.0191132017279752	0.107101288977905
GO:0042809	nuclear vitamin D receptor binding	6/2881	15/18639	0.4	2.58785144047206	0.0193062612244756	0.107708615252337
GO:0140104	molecular carrier activity	51/2881	249/18639	0.204819277108434	1.32510465325376	0.0196802969400126	0.109315885186446
GO:0046875	ephrin receptor binding	9/2881	28/18639	0.321428571428571	2.07952347895076	0.0211855360796305	0.116658016854069
GO:0051537	2 iron, 2 sulfur cluster binding	9/2881	28/18639	0.321428571428571	2.07952347895076	0.0211855360796305	0.116658016854069
GO:0048487	beta-tubulin binding	12/2881	42/18639	0.285714285714286	1.8484653146229	0.0220221117763221	0.120741923187421
GO:0005496	steroid binding	25/2881	108/18639	0.231481481481481	1.49759921323614	0.0226426573204591	0.123611416788086
GO:0043495	protein-membrane adaptor activity	13/2881	47/18639	0.276595744680851	1.78947174075196	0.022902511420907	0.123965934159122
GO:0140938	histone H3 methyltransferase activity	13/2881	47/18639	0.276595744680851	1.78947174075196	0.022902511420907	0.123965934159122
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	8/2881	24/18639	0.333333333333333	2.15654286706005	0.0234233713934493	0.124663298796935
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	8/2881	24/18639	0.333333333333333	2.15654286706005	0.0234233713934493	0.124663298796935
GO:0043998	histone H2A acetyltransferase activity	8/2881	24/18639	0.333333333333333	2.15654286706005	0.0234233713934493	0.124663298796935
GO:0140033	acetylation-dependent protein binding	8/2881	24/18639	0.333333333333333	2.15654286706005	0.0234233713934493	0.124663298796935
GO:0016779	nucleotidyltransferase activity	30/2881	136/18639	0.220588235294118	1.42712395614268	0.0255982834960859	0.135670902529255
GO:0008200	ion channel inhibitor activity	12/2881	43/18639	0.27906976744186	1.80547774916655	0.0263737386896973	0.137313115912919
GO:0004708	MAP kinase kinase activity	6/2881	16/18639	0.375	2.42611072544255	0.0269333334022179	0.137313115912919
GO:0015923	mannosidase activity	6/2881	16/18639	0.375	2.42611072544255	0.0269333334022179	0.137313115912919
GO:0017070	U6 snRNA binding	6/2881	16/18639	0.375	2.42611072544255	0.0269333334022179	0.137313115912919
GO:0030275	LRR domain binding	6/2881	16/18639	0.375	2.42611072544255	0.0269333334022179	0.137313115912919
GO:0043023	ribosomal large subunit binding	6/2881	16/18639	0.375	2.42611072544255	0.0269333334022179	0.137313115912919
GO:0097027	ubiquitin-protein transferase activator activity	6/2881	16/18639	0.375	2.42611072544255	0.0269333334022179	0.137313115912919
GO:0034452	dynactin binding	5/2881	12/18639	0.416666666666667	2.69567858382506	0.026939991157475	0.137313115912919
GO:0097371	MDM2/MDM4 family protein binding	5/2881	12/18639	0.416666666666667	2.69567858382506	0.026939991157475	0.137313115912919
GO:0101005	deubiquitinase activity	26/2881	115/18639	0.226086956521739	1.46269864026682	0.0269991647374266	0.137313115912919
GO:0140693	molecular condensate scaffold activity	13/2881	48/18639	0.270833333333333	1.75219107948629	0.0270955912689801	0.137313115912919
GO:0034212	protein N-acetyltransferase activity	14/2881	53/18639	0.264150943396226	1.70895849842494	0.0274834248224911	0.138177535075924
GO:0140296	general transcription initiation factor binding	14/2881	53/18639	0.264150943396226	1.70895849842494	0.0274834248224911	0.138177535075924
GO:0008234	cysteine-type peptidase activity	39/2881	187/18639	0.20855614973262	1.34928083126217	0.0289734520752292	0.145095397794061
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	8/2881	25/18639	0.32	2.07028115237765	0.0299026291297249	0.149161350011804
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	11/2881	39/18639	0.282051282051282	1.8247670413585	0.030376206299678	0.150931775051525
GO:0008276	protein methyltransferase activity	22/2881	95/18639	0.231578947368421	1.49822978132593	0.0309210956922161	0.153041376344354
GO:0002039	p53 binding	17/2881	69/18639	0.246376811594203	1.59396646695743	0.0311585022329689	0.153618662171847
GO:0019205	nucleobase-containing compound kinase activity	12/2881	44/18639	0.272727272727273	1.76444416395822	0.0313190823927551	0.15381418070882
GO:0015485	cholesterol binding	14/2881	54/18639	0.259259259259259	1.67731111882448	0.0319910519589182	0.156510069583631
GO:0031210	phosphatidylcholine binding	9/2881	30/18639	0.3	1.94088858035404	0.0329608289748859	0.159415112000209
GO:0031624	ubiquitin conjugating enzyme binding	9/2881	30/18639	0.3	1.94088858035404	0.0329608289748859	0.159415112000209
GO:0070566	adenylyltransferase activity	9/2881	30/18639	0.3	1.94088858035404	0.0329608289748859	0.159415112000209
GO:0140767	enzyme-substrate adaptor activity	30/2881	139/18639	0.215827338129496	1.39632271967917	0.0335870723831917	0.161828621482651
GO:0050997	quaternary ammonium group binding	11/2881	40/18639	0.275	1.77914786532454	0.0362318732625044	0.171718051214888
GO:0031489	myosin V binding	6/2881	17/18639	0.352941176470588	2.28339832982829	0.0363145878748467	0.171718051214888
GO:0032183	SUMO binding	6/2881	17/18639	0.352941176470588	2.28339832982829	0.0363145878748467	0.171718051214888
GO:0032977	membrane insertase activity	6/2881	17/18639	0.352941176470588	2.28339832982829	0.0363145878748467	0.171718051214888
GO:0051787	misfolded protein binding	6/2881	17/18639	0.352941176470588	2.28339832982829	0.0363145878748467	0.171718051214888
GO:0004112	cyclic-nucleotide phosphodiesterase activity	8/2881	26/18639	0.307692307692308	1.99065495420928	0.0375126416073936	0.173490247644143
GO:0050681	nuclear androgen receptor binding	8/2881	26/18639	0.307692307692308	1.99065495420928	0.0375126416073936	0.173490247644143
GO:0120014	phospholipid transfer activity	8/2881	26/18639	0.307692307692308	1.99065495420928	0.0375126416073936	0.173490247644143
GO:1901981	phosphatidylinositol phosphate binding	38/2881	185/18639	0.205405405405405	1.32889668564781	0.0379905639845442	0.173490247644143
GO:0002161	aminoacyl-tRNA editing activity	5/2881	13/18639	0.384615384615385	2.48831869276159	0.0383260688584939	0.173490247644143
GO:0004535	poly(A)-specific ribonuclease activity	5/2881	13/18639	0.384615384615385	2.48831869276159	0.0383260688584939	0.173490247644143
GO:0019855	calcium channel inhibitor activity	5/2881	13/18639	0.384615384615385	2.48831869276159	0.0383260688584939	0.173490247644143
GO:0043560	insulin receptor substrate binding	5/2881	13/18639	0.384615384615385	2.48831869276159	0.0383260688584939	0.173490247644143
GO:0046975	histone H3K36 methyltransferase activity	5/2881	13/18639	0.384615384615385	2.48831869276159	0.0383260688584939	0.173490247644143
GO:0140333	glycerophospholipid flippase activity	5/2881	13/18639	0.384615384615385	2.48831869276159	0.0383260688584939	0.173490247644143
GO:0140410	monoatomic cation:bicarbonate symporter activity	5/2881	13/18639	0.384615384615385	2.48831869276159	0.0383260688584939	0.173490247644143
GO:0140852	histone ubiquitin ligase activity	5/2881	13/18639	0.384615384615385	2.48831869276159	0.0383260688584939	0.173490247644143
GO:0004843	cysteine-type deubiquitinase activity	24/2881	108/18639	0.222222222222222	1.4376952447067	0.0392164513353946	0.176891227300078
GO:0005164	tumor necrosis factor receptor binding	9/2881	31/18639	0.290322580645161	1.87827927131037	0.0402760026520377	0.181028534888311
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	10/2881	36/18639	0.277777777777778	1.79711905588337	0.0419514758082841	0.186581388909571
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	10/2881	36/18639	0.277777777777778	1.79711905588337	0.0419514758082841	0.186581388909571
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	10/2881	36/18639	0.277777777777778	1.79711905588337	0.0419514758082841	0.186581388909571
GO:0008170	N-methyltransferase activity	22/2881	98/18639	0.224489795918367	1.45236560434656	0.0423947599641994	0.187490763564093
GO:0140035	ubiquitin-like protein reader activity	7/2881	22/18639	0.318181818181818	2.05851819128459	0.0424507389201721	0.187490763564093
GO:0001727	lipid kinase activity	11/2881	41/18639	0.268292682926829	1.73575401495077	0.0428346501614986	0.187881637949746
GO:0017080	sodium channel regulator activity	11/2881	41/18639	0.268292682926829	1.73575401495077	0.0428346501614986	0.187881637949746
GO:0030291	protein serine/threonine kinase inhibitor activity	12/2881	46/18639	0.260869565217391	1.68772920030786	0.0431373098067198	0.188558962454115
GO:0008266	poly(U) RNA binding	8/2881	27/18639	0.296296296296296	1.91692699294227	0.0463189414101947	0.201772922855369
GO:0042054	histone methyltransferase activity	16/2881	67/18639	0.238805970149254	1.54498593461018	0.0464790899106307	0.201779530260485
GO:0000400	four-way junction DNA binding	6/2881	18/18639	0.333333333333333	2.15654286706005	0.0475528743150259	0.205041546199027
GO:0070628	proteasome binding	6/2881	18/18639	0.333333333333333	2.15654286706005	0.0475528743150259	0.205041546199027
GO:0051059	NF-kappaB binding	9/2881	32/18639	0.28125	1.81958304408192	0.0486138348198136	0.208908100982442
GO:0042826	histone deacetylase binding	27/2881	127/18639	0.21259842519685	1.3754328522194	0.0496107956156501	0.21247451859632
GO:0016859	cis-trans isomerase activity	11/2881	42/18639	0.261904761904762	1.69442653840432	0.0502197444272065	0.214032764653434
GO:0046982	protein heterodimerization activity	69/2881	369/18639	0.186991869918699	1.20976794981417	0.0503111608737239	0.214032764653434
GO:0004705	JUN kinase activity	5/2881	14/18639	0.357142857142857	2.31058164327862	0.052233148623241	0.219187683247932
GO:0019992	diacylglycerol binding	5/2881	14/18639	0.357142857142857	2.31058164327862	0.052233148623241	0.219187683247932
GO:0034236	protein kinase A catalytic subunit binding	5/2881	14/18639	0.357142857142857	2.31058164327862	0.052233148623241	0.219187683247932
GO:0046030	inositol trisphosphate phosphatase activity	5/2881	14/18639	0.357142857142857	2.31058164327862	0.052233148623241	0.219187683247932
GO:0005548	phospholipid transporter activity	16/2881	68/18639	0.235294117647059	1.52226555321886	0.0523844777573675	0.219187683247932
GO:0005158	insulin receptor binding	7/2881	23/18639	0.304347826086957	1.96901740035917	0.053149558863484	0.221659799588038
GO:0005131	growth hormone receptor binding	4/2881	10/18639	0.4	2.58785144047206	0.0549502954288477	0.22260119676909
GO:0005522	profilin binding	4/2881	10/18639	0.4	2.58785144047206	0.0549502954288477	0.22260119676909
GO:0008140	cAMP response element binding protein binding	4/2881	10/18639	0.4	2.58785144047206	0.0549502954288477	0.22260119676909
GO:0016303	1-phosphatidylinositol-3-kinase activity	4/2881	10/18639	0.4	2.58785144047206	0.0549502954288477	0.22260119676909
GO:0033204	ribonuclease P RNA binding	4/2881	10/18639	0.4	2.58785144047206	0.0549502954288477	0.22260119676909
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	4/2881	10/18639	0.4	2.58785144047206	0.0549502954288477	0.22260119676909
GO:0099122	RNA polymerase II C-terminal domain binding	4/2881	10/18639	0.4	2.58785144047206	0.0549502954288477	0.22260119676909
GO:1905394	retromer complex binding	4/2881	10/18639	0.4	2.58785144047206	0.0549502954288477	0.22260119676909
GO:1990757	ubiquitin ligase activator activity	4/2881	10/18639	0.4	2.58785144047206	0.0549502954288477	0.22260119676909
GO:0008408	3'-5' exonuclease activity	14/2881	58/18639	0.241379310344828	1.56163448994004	0.0554075914967394	0.22374113137731
GO:0005246	calcium channel regulator activity	13/2881	53/18639	0.245283018867925	1.58689003425173	0.0566949861745255	0.227036747792062
GO:0016251	RNA polymerase II general transcription initiation factor activity	13/2881	53/18639	0.245283018867925	1.58689003425173	0.0566949861745255	0.227036747792062
GO:0035064	methylated histone binding	17/2881	74/18639	0.22972972972973	1.48626603000084	0.0567591869480154	0.227036747792062
GO:0032266	phosphatidylinositol-3-phosphate binding	12/2881	48/18639	0.25	1.61740715029504	0.0577347428670999	0.229891265717915
GO:0019956	chemokine binding	9/2881	33/18639	0.272727272727273	1.76444416395822	0.058015012810889	0.229891265717915
GO:0140311	protein sequestering activity	9/2881	33/18639	0.272727272727273	1.76444416395822	0.058015012810889	0.229891265717915
GO:0005525	GTP binding	70/2881	378/18639	0.185185185185185	1.19807937058892	0.0582248536518757	0.230006254177596
GO:0016279	protein-lysine N-methyltransferase activity	16/2881	69/18639	0.231884057971014	1.50020373360699	0.0587923194251104	0.231528886404769
GO:0140036	ubiquitin-modified protein reader activity	6/2881	19/18639	0.315789473684211	2.04304061089899	0.0607110747304672	0.237976935418047
GO:0048306	calcium-dependent protein binding	18/2881	80/18639	0.225	1.45566643526553	0.0608038553544539	0.237976935418047
GO:0017069	snRNA binding	13/2881	54/18639	0.240740740740741	1.55750318176559	0.0645279409258157	0.25177773269214
GO:0140789	histone phosphatase activity	28/2881	136/18639	0.205882352941176	1.3319823590665	0.0653766286127401	0.25358465460853
GO:0001091	RNA polymerase II general transcription initiation factor binding	7/2881	24/18639	0.291666666666667	1.88697500867754	0.0653897537040865	0.25358465460853
GO:0016278	lysine N-methyltransferase activity	16/2881	70/18639	0.228571428571429	1.47877225169832	0.0657168946899155	0.254078693147637
GO:0030971	receptor tyrosine kinase binding	18/2881	81/18639	0.222222222222222	1.4376952447067	0.0673371678580986	0.257764204821173
GO:0001223	transcription coactivator binding	11/2881	44/18639	0.25	1.61740715029504	0.0674493844017151	0.257764204821173
GO:0043014	alpha-tubulin binding	11/2881	44/18639	0.25	1.61740715029504	0.0674493844017151	0.257764204821173
GO:0003785	actin monomer binding	8/2881	29/18639	0.275862068965517	1.78472513136004	0.0677075220144328	0.257764204821173
GO:0043178	alcohol binding	20/2881	92/18639	0.217391304347826	1.40644100025655	0.0679906774731207	0.257764204821173
GO:0019843	rRNA binding	15/2881	65/18639	0.230769230769231	1.49299121565696	0.0681975919510925	0.257764204821173
GO:0120013	lipid transfer activity	15/2881	65/18639	0.230769230769231	1.49299121565696	0.0681975919510925	0.257764204821173
GO:0004559	alpha-mannosidase activity	5/2881	15/18639	0.333333333333333	2.15654286706005	0.068696592322624	0.257764204821173
GO:0008252	nucleotidase activity	5/2881	15/18639	0.333333333333333	2.15654286706005	0.068696592322624	0.257764204821173
GO:0050700	CARD domain binding	5/2881	15/18639	0.333333333333333	2.15654286706005	0.068696592322624	0.257764204821173
GO:0140034	methylation-dependent protein binding	17/2881	76/18639	0.223684210526316	1.44715376605345	0.0702173959796038	0.262695669664871
GO:0004540	RNA nuclease activity	25/2881	121/18639	0.206611570247934	1.33670012421077	0.0755694445452392	0.278907949260773
GO:0000339	RNA cap binding	6/2881	20/18639	0.3	1.94088858035404	0.0758113564754471	0.278907949260773
GO:0015173	aromatic amino acid transmembrane transporter activity	4/2881	11/18639	0.363636363636364	2.35259221861096	0.0760857377307296	0.278907949260773
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4/2881	11/18639	0.363636363636364	2.35259221861096	0.0760857377307296	0.278907949260773
GO:0034056	estrogen response element binding	4/2881	11/18639	0.363636363636364	2.35259221861096	0.0760857377307296	0.278907949260773
GO:0042608	T cell receptor binding	4/2881	11/18639	0.363636363636364	2.35259221861096	0.0760857377307296	0.278907949260773
GO:0180030	inositol phosphate kinase activity	4/2881	11/18639	0.363636363636364	2.35259221861096	0.0760857377307296	0.278907949260773
GO:0017056	structural constituent of nuclear pore	7/2881	25/18639	0.28	1.81149600833044	0.0791903021496714	0.287909031514033
GO:0042974	nuclear retinoic acid receptor binding	7/2881	25/18639	0.28	1.81149600833044	0.0791903021496714	0.287909031514033
GO:0019905	syntaxin binding	14/2881	61/18639	0.229508196721311	1.48483279371348	0.079220252382006	0.287909031514033
GO:0001968	fibronectin binding	8/2881	30/18639	0.266666666666667	1.72523429364804	0.0803426831197227	0.290329241273543
GO:0008187	poly-pyrimidine tract binding	8/2881	30/18639	0.266666666666667	1.72523429364804	0.0803426831197227	0.290329241273543
GO:0016410	N-acyltransferase activity	20/2881	94/18639	0.212765957446809	1.37651672365535	0.081529065415906	0.293781788127571
GO:0030165	PDZ domain binding	18/2881	83/18639	0.216867469879518	1.4030519857981	0.0817912149538507	0.293893857122311
GO:0004857	enzyme inhibitor activity	75/2881	416/18639	0.180288461538462	1.166399387232	0.082869567435718	0.29692983036122
GO:0016247	channel regulator activity	33/2881	168/18639	0.196428571428571	1.27081990380324	0.0836870296131879	0.299016577719031
GO:0004707	MAP kinase activity	5/2881	16/18639	0.3125	2.0217589378688	0.0876798918318994	0.309802284472711
GO:0008142	oxysterol binding	5/2881	16/18639	0.3125	2.0217589378688	0.0876798918318994	0.309802284472711
GO:0140327	flippase activity	5/2881	16/18639	0.3125	2.0217589378688	0.0876798918318994	0.309802284472711
GO:0140328	floppase activity	5/2881	16/18639	0.3125	2.0217589378688	0.0876798918318994	0.309802284472711
GO:0043539	protein serine/threonine kinase activator activity	16/2881	73/18639	0.219178082191781	1.41800078929976	0.0896989755169365	0.315281311197859
GO:0051117	ATPase binding	18/2881	84/18639	0.214285714285714	1.38634898596717	0.089726285105051	0.315281311197859
GO:0043022	ribosome binding	23/2881	112/18639	0.205357142857143	1.32858444488521	0.0902001941543156	0.315994147914669
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	10/2881	41/18639	0.24390243902439	1.57795819540979	0.0906744213748853	0.315994147914669
GO:0016877	ligase activity, forming carbon-sulfur bonds	10/2881	41/18639	0.24390243902439	1.57795819540979	0.0906744213748853	0.315994147914669
GO:0140223	general transcription initiation factor activity	15/2881	68/18639	0.220588235294118	1.42712395614268	0.0939057714111196	0.326361041625531
GO:0050750	low-density lipoprotein particle receptor binding	7/2881	26/18639	0.269230769230769	1.74182308493312	0.0945452297178791	0.327688098640714
GO:0141108	transporter regulator activity	33/2881	170/18639	0.194117647058824	1.25586908140556	0.0949345216269158	0.328143237797383
GO:0002020	protease binding	27/2881	136/18639	0.198529411764706	1.28441156052841	0.0987516863794816	0.336057095050073
GO:0003684	damaged DNA binding	16/2881	74/18639	0.216216216216216	1.39883861647138	0.098785813742846	0.336057095050073
GO:0022804	active transmembrane transporter activity	81/2881	457/18639	0.177242888402626	1.14669566016541	0.0996616121676537	0.336057095050073
GO:0000340	RNA 7-methylguanosine cap binding	4/2881	12/18639	0.333333333333333	2.15654286706005	0.100658611017357	0.336057095050073
GO:0004126	cytidine deaminase activity	4/2881	12/18639	0.333333333333333	2.15654286706005	0.100658611017357	0.336057095050073
GO:0004300	enoyl-CoA hydratase activity	4/2881	12/18639	0.333333333333333	2.15654286706005	0.100658611017357	0.336057095050073
GO:0004526	ribonuclease P activity	4/2881	12/18639	0.333333333333333	2.15654286706005	0.100658611017357	0.336057095050073
GO:0005049	nuclear export signal receptor activity	4/2881	12/18639	0.333333333333333	2.15654286706005	0.100658611017357	0.336057095050073
GO:0016273	arginine N-methyltransferase activity	4/2881	12/18639	0.333333333333333	2.15654286706005	0.100658611017357	0.336057095050073
GO:0016274	protein-arginine N-methyltransferase activity	4/2881	12/18639	0.333333333333333	2.15654286706005	0.100658611017357	0.336057095050073
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	4/2881	12/18639	0.333333333333333	2.15654286706005	0.100658611017357	0.336057095050073
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/2881	12/18639	0.333333333333333	2.15654286706005	0.100658611017357	0.336057095050073
GO:1990817	poly(A) RNA polymerase activity	4/2881	12/18639	0.333333333333333	2.15654286706005	0.100658611017357	0.336057095050073
GO:0061980	regulatory RNA binding	13/2881	58/18639	0.224137931034483	1.45008916923003	0.102793522461012	0.342286284215726
GO:0019894	kinesin binding	10/2881	42/18639	0.238095238095238	1.54038776218575	0.103316507921035	0.343129498891792
GO:0008080	N-acetyltransferase activity	15/2881	69/18639	0.217391304347826	1.40644100025655	0.1036595080739	0.343372120494794
GO:0099106	ion channel regulator activity	31/2881	160/18639	0.19375	1.25349054147865	0.104815692273999	0.346300157331237
GO:0004864	protein phosphatase inhibitor activity	12/2881	53/18639	0.226415094339623	1.46482157007852	0.107438554319342	0.354046220451303
GO:0004722	protein serine/threonine phosphatase activity	21/2881	103/18639	0.203883495145631	1.31905049150275	0.107909056841247	0.354677830237898
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	5/2881	17/18639	0.294117647058824	1.90283194152357	0.109082101814005	0.356690060430369
GO:0008429	phosphatidylethanolamine binding	5/2881	17/18639	0.294117647058824	1.90283194152357	0.109082101814005	0.356690060430369
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	7/2881	27/18639	0.259259259259259	1.67731111882448	0.111424430625569	0.363415066040316
GO:0070034	telomerase RNA binding	6/2881	22/18639	0.272727272727273	1.76444416395822	0.111730714880046	0.3634820187402
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	11/2881	48/18639	0.229166666666667	1.48262322110378	0.112170234882428	0.363980966251143
GO:0019001	guanyl nucleotide binding	71/2881	400/18639	0.1775	1.14835907670948	0.113862212551961	0.367595772502778
GO:0032561	guanyl ribonucleotide binding	71/2881	400/18639	0.1775	1.14835907670948	0.113862212551961	0.367595772502778
GO:0003779	actin binding	78/2881	443/18639	0.17607223476298	1.13912196589628	0.116049254084382	0.373707977709706
GO:0008375	acetylglucosaminyltransferase activity	10/2881	43/18639	0.232558139534884	1.50456479097213	0.116922477321508	0.375569169578176
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	17/2881	82/18639	0.207317073170732	1.34126446609832	0.122672822419583	0.393047431026976
GO:0008253	5'-nucleotidase activity	4/2881	13/18639	0.307692307692308	1.99065495420928	0.128361963087962	0.409214077814256
GO:0070123	transforming growth factor beta receptor activity, type III	4/2881	13/18639	0.307692307692308	1.99065495420928	0.128361963087962	0.409214077814256
GO:0019789	SUMO transferase activity	7/2881	28/18639	0.25	1.61740715029504	0.129775139653285	0.41165580458598
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	7/2881	28/18639	0.25	1.61740715029504	0.129775139653285	0.41165580458598
GO:0004602	glutathione peroxidase activity	6/2881	23/18639	0.260869565217391	1.68772920030786	0.132406417003538	0.417956497046817
GO:0140313	molecular sequestering activity	12/2881	55/18639	0.218181818181818	1.41155533116658	0.132718443363397	0.417956497046817
GO:0098641	cadherin binding involved in cell-cell adhesion	5/2881	18/18639	0.277777777777778	1.79711905588337	0.132747189313612	0.417956497046817
GO:0000217	DNA secondary structure binding	9/2881	39/18639	0.230769230769231	1.49299121565696	0.137567671875381	0.432064391667862
GO:0015035	protein-disulfide reductase activity	8/2881	34/18639	0.235294117647059	1.52226555321886	0.143658150142098	0.450081692070809
GO:0019209	kinase activator activity	28/2881	148/18639	0.189189189189189	1.22398378941246	0.145954374472175	0.456152246507632
GO:0019212	phosphatase inhibitor activity	12/2881	56/18639	0.214285714285714	1.38634898596717	0.146480604509436	0.456674825823537
GO:0043236	laminin binding	7/2881	29/18639	0.241379310344828	1.56163448994004	0.149523927083828	0.463888866464951
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	7/2881	29/18639	0.241379310344828	1.56163448994004	0.149523927083828	0.463888866464951
GO:0016407	acetyltransferase activity	19/2881	96/18639	0.197916666666667	1.2804473273169	0.150137132866954	0.464657987851011
GO:0016835	carbon-oxygen lyase activity	16/2881	79/18639	0.20253164556962	1.3103045268213	0.152424888993974	0.469792460110554
GO:0015036	disulfide oxidoreductase activity	9/2881	40/18639	0.225	1.45566643526553	0.154569394018486	0.469792460110554
GO:0030552	cAMP binding	6/2881	24/18639	0.25	1.61740715029504	0.154745304770022	0.469792460110554
GO:0035035	histone acetyltransferase binding	6/2881	24/18639	0.25	1.61740715029504	0.154745304770022	0.469792460110554
GO:0050699	WW domain binding	6/2881	24/18639	0.25	1.61740715029504	0.154745304770022	0.469792460110554
GO:0070300	phosphatidic acid binding	6/2881	24/18639	0.25	1.61740715029504	0.154745304770022	0.469792460110554
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	31/2881	167/18639	0.18562874251497	1.20094902177596	0.1566336410015	0.469792460110554
GO:0042800	histone H3K4 methyltransferase activity	5/2881	19/18639	0.263157894736842	1.70253384241583	0.158474373093306	0.469792460110554
GO:0046624	sphingolipid transporter activity	5/2881	19/18639	0.263157894736842	1.70253384241583	0.158474373093306	0.469792460110554
GO:1990380	K48-linked deubiquitinase activity	5/2881	19/18639	0.263157894736842	1.70253384241583	0.158474373093306	0.469792460110554
GO:0051015	actin filament binding	38/2881	209/18639	0.181818181818182	1.17629610930548	0.15855015974853	0.469792460110554
GO:0005545	1-phosphatidylinositol binding	4/2881	14/18639	0.285714285714286	1.8484653146229	0.158813488873851	0.469792460110554
GO:0008174	mRNA methyltransferase activity	4/2881	14/18639	0.285714285714286	1.8484653146229	0.158813488873851	0.469792460110554
GO:0032036	myosin heavy chain binding	4/2881	14/18639	0.285714285714286	1.8484653146229	0.158813488873851	0.469792460110554
GO:0042043	neurexin family protein binding	4/2881	14/18639	0.285714285714286	1.8484653146229	0.158813488873851	0.469792460110554
GO:0044548	S100 protein binding	4/2881	14/18639	0.285714285714286	1.8484653146229	0.158813488873851	0.469792460110554
GO:0061665	SUMO ligase activity	4/2881	14/18639	0.285714285714286	1.8484653146229	0.158813488873851	0.469792460110554
GO:0070742	C2H2 zinc finger domain binding	4/2881	14/18639	0.285714285714286	1.8484653146229	0.158813488873851	0.469792460110554
GO:1990825	sequence-specific mRNA binding	4/2881	14/18639	0.285714285714286	1.8484653146229	0.158813488873851	0.469792460110554
GO:0005154	epidermal growth factor receptor binding	8/2881	35/18639	0.228571428571429	1.47877225169832	0.162486155254769	0.479541506923589
GO:0033192	calmodulin-dependent protein phosphatase activity	16/2881	81/18639	0.197530864197531	1.27795132862818	0.177569514309113	0.514506656494742
GO:0140791	histone H2AXS140 phosphatase activity	16/2881	81/18639	0.197530864197531	1.27795132862818	0.177569514309113	0.514506656494742
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	16/2881	81/18639	0.197530864197531	1.27795132862818	0.177569514309113	0.514506656494742
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	16/2881	81/18639	0.197530864197531	1.27795132862818	0.177569514309113	0.514506656494742
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	16/2881	81/18639	0.197530864197531	1.27795132862818	0.177569514309113	0.514506656494742
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	16/2881	81/18639	0.197530864197531	1.27795132862818	0.177569514309113	0.514506656494742
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	16/2881	81/18639	0.197530864197531	1.27795132862818	0.177569514309113	0.514506656494742
GO:1990439	MAP kinase serine/threonine phosphatase activity	16/2881	81/18639	0.197530864197531	1.27795132862818	0.177569514309113	0.514506656494742
GO:0003707	nuclear steroid receptor activity	6/2881	25/18639	0.24	1.55271086428323	0.178604779281712	0.516330180105313
GO:1990518	single-stranded 3'-5' DNA helicase activity	10/2881	47/18639	0.212765957446809	1.37651672365535	0.180479651387294	0.520567157742943
GO:0004713	protein tyrosine kinase activity	26/2881	140/18639	0.185714285714286	1.20150245450488	0.181052827599744	0.52103890657664
GO:0005484	SNAP receptor activity	8/2881	36/18639	0.222222222222222	1.4376952447067	0.182386670495271	0.523246850979272
GO:0140597	protein carrier chaperone	34/2881	188/18639	0.180851063829787	1.17003921510705	0.182642768738048	0.523246850979272
GO:0097110	scaffold protein binding	14/2881	70/18639	0.2	1.29392572023603	0.184854378705168	0.525136357765748
GO:0016408	C-acyltransferase activity	5/2881	20/18639	0.25	1.61740715029504	0.186028711965926	0.525136357765748
GO:0052745	inositol phosphate phosphatase activity	5/2881	20/18639	0.25	1.61740715029504	0.186028711965926	0.525136357765748
GO:0140939	histone H4 methyltransferase activity	5/2881	20/18639	0.25	1.61740715029504	0.186028711965926	0.525136357765748
GO:0005516	calmodulin binding	37/2881	207/18639	0.178743961352657	1.15640704465539	0.190381731139364	0.525136357765748
GO:0033549	MAP kinase phosphatase activity	16/2881	82/18639	0.195121951219512	1.26236655632783	0.190877803252029	0.525136357765748
GO:0035198	miRNA binding	9/2881	42/18639	0.214285714285714	1.38634898596717	0.191418949752717	0.525136357765748
GO:0061578	K63-linked deubiquitinase activity	4/2881	15/18639	0.266666666666667	1.72523429364804	0.191583269437934	0.525136357765748
GO:0120283	protein serine/threonine kinase binding	4/2881	15/18639	0.266666666666667	1.72523429364804	0.191583269437934	0.525136357765748
GO:0004445	inositol-polyphosphate 5-phosphatase activity	3/2881	10/18639	0.3	1.94088858035404	0.191757854373169	0.525136357765748
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/2881	10/18639	0.3	1.94088858035404	0.191757854373169	0.525136357765748
GO:0005528	FK506 binding	3/2881	10/18639	0.3	1.94088858035404	0.191757854373169	0.525136357765748
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	3/2881	10/18639	0.3	1.94088858035404	0.191757854373169	0.525136357765748
GO:0031419	cobalamin binding	3/2881	10/18639	0.3	1.94088858035404	0.191757854373169	0.525136357765748
GO:0031996	thioesterase binding	3/2881	10/18639	0.3	1.94088858035404	0.191757854373169	0.525136357765748
GO:0047429	nucleoside triphosphate diphosphatase activity	3/2881	10/18639	0.3	1.94088858035404	0.191757854373169	0.525136357765748
GO:0051864	histone H3K36 demethylase activity	3/2881	10/18639	0.3	1.94088858035404	0.191757854373169	0.525136357765748
GO:0051880	G-quadruplex DNA binding	3/2881	10/18639	0.3	1.94088858035404	0.191757854373169	0.525136357765748
GO:0070097	delta-catenin binding	3/2881	10/18639	0.3	1.94088858035404	0.191757854373169	0.525136357765748
GO:0140999	histone H3K4 trimethyltransferase activity	3/2881	10/18639	0.3	1.94088858035404	0.191757854373169	0.525136357765748
GO:0001786	phosphatidylserine binding	12/2881	59/18639	0.203389830508475	1.31585666464681	0.19197201757946	0.525136357765748
GO:0070325	lipoprotein particle receptor binding	7/2881	31/18639	0.225806451612903	1.46088387768584	0.192833304098759	0.526360435222364
GO:0043138	3'-5' DNA helicase activity	10/2881	48/18639	0.208333333333333	1.34783929191253	0.198455813625417	0.540547740752741
GO:0005112	Notch binding	6/2881	26/18639	0.230769230769231	1.49299121565696	0.203822644150862	0.552127338176541
GO:0005160	transforming growth factor beta receptor binding	6/2881	26/18639	0.230769230769231	1.49299121565696	0.203822644150862	0.552127338176541
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	11/2881	54/18639	0.203703703703704	1.31788730764781	0.204009315206741	0.552127338176541
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	16/2881	83/18639	0.192771084337349	1.24715732070943	0.204650906492279	0.552687798425008
GO:0008017	microtubule binding	48/2881	276/18639	0.173913043478261	1.12515280020524	0.206583230675039	0.556724299615783
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	12/2881	60/18639	0.2	1.29392572023603	0.208430059671798	0.560513817975743
GO:0004386	helicase activity	28/2881	155/18639	0.180645161290323	1.16870710214867	0.211860423423161	0.568536832477342
GO:0005518	collagen binding	14/2881	72/18639	0.194444444444444	1.25798333911836	0.214799864070058	0.573737011895826
GO:0008373	sialyltransferase activity	5/2881	21/18639	0.238095238095238	1.54038776218575	0.215151379460935	0.573737011895826
GO:0140312	cargo adaptor activity	5/2881	21/18639	0.238095238095238	1.54038776218575	0.215151379460935	0.573737011895826
GO:0120015	sterol transfer activity	7/2881	32/18639	0.21875	1.41523125650816	0.216166457102717	0.575237936055766
GO:0004527	exonuclease activity	16/2881	84/18639	0.19047619047619	1.2323102097486	0.218866573475091	0.579996419708991
GO:0017018	myosin phosphatase activity	16/2881	84/18639	0.19047619047619	1.2323102097486	0.218866573475091	0.579996419708991
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	12/2881	61/18639	0.19672131147541	1.27271382318298	0.225470750199328	0.592076030514424
GO:0016836	hydro-lyase activity	12/2881	61/18639	0.19672131147541	1.27271382318298	0.225470750199328	0.592076030514424
GO:0000062	fatty-acyl-CoA binding	4/2881	16/18639	0.25	1.61740715029504	0.226217728639945	0.592076030514424
GO:0005024	transforming growth factor beta receptor activity	4/2881	16/18639	0.25	1.61740715029504	0.226217728639945	0.592076030514424
GO:0015562	efflux transmembrane transporter activity	4/2881	16/18639	0.25	1.61740715029504	0.226217728639945	0.592076030514424
GO:0022858	alanine transmembrane transporter activity	4/2881	16/18639	0.25	1.61740715029504	0.226217728639945	0.592076030514424
GO:0004364	glutathione transferase activity	6/2881	27/18639	0.222222222222222	1.4376952447067	0.230222133729517	0.601075634355174
GO:0046332	SMAD binding	15/2881	79/18639	0.189873417721519	1.22841049389496	0.232215614277591	0.601075634355174
GO:0030295	protein kinase activator activity	25/2881	139/18639	0.179856115107914	1.16360226639931	0.234727295667166	0.601075634355174
GO:0000099	sulfur amino acid transmembrane transporter activity	3/2881	11/18639	0.272727272727273	1.76444416395822	0.235134898114083	0.601075634355174
GO:0008432	JUN kinase binding	3/2881	11/18639	0.272727272727273	1.76444416395822	0.235134898114083	0.601075634355174
GO:0019206	nucleoside kinase activity	3/2881	11/18639	0.272727272727273	1.76444416395822	0.235134898114083	0.601075634355174
GO:0019215	intermediate filament binding	3/2881	11/18639	0.272727272727273	1.76444416395822	0.235134898114083	0.601075634355174
GO:0032404	mismatch repair complex binding	3/2881	11/18639	0.272727272727273	1.76444416395822	0.235134898114083	0.601075634355174
GO:0034511	U3 snoRNA binding	3/2881	11/18639	0.272727272727273	1.76444416395822	0.235134898114083	0.601075634355174
GO:0034713	type I transforming growth factor beta receptor binding	3/2881	11/18639	0.272727272727273	1.76444416395822	0.235134898114083	0.601075634355174
GO:0048185	activin binding	3/2881	11/18639	0.272727272727273	1.76444416395822	0.235134898114083	0.601075634355174
GO:0035401	histone H3Y41 kinase activity	21/2881	115/18639	0.182608695652174	1.1814104402155	0.235799325112604	0.601075634355174
GO:0140801	histone H2AXY142 kinase activity	21/2881	115/18639	0.182608695652174	1.1814104402155	0.235799325112604	0.601075634355174
GO:0032813	tumor necrosis factor receptor superfamily binding	10/2881	50/18639	0.2	1.29392572023603	0.236541467264694	0.601761492721382
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	7/2881	33/18639	0.212121212121212	1.37234546085639	0.240448501244005	0.609263931438993
GO:0019239	deaminase activity	7/2881	33/18639	0.212121212121212	1.37234546085639	0.240448501244005	0.609263931438993
GO:0030021	extracellular matrix structural constituent conferring compression resistance	5/2881	22/18639	0.227272727272727	1.47037013663185	0.245569221984726	0.619769941199546
GO:0140517	protein-RNA adaptor activity	5/2881	22/18639	0.227272727272727	1.47037013663185	0.245569221984726	0.619769941199546
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	22/2881	122/18639	0.180327868852459	1.16665433791773	0.248265798494353	0.625334842940232
GO:0140303	intramembrane lipid transporter activity	9/2881	45/18639	0.2	1.29392572023603	0.25279451900541	0.635483454891069
GO:0003774	cytoskeletal motor activity	27/2881	153/18639	0.176470588235294	1.14169916491414	0.256175978905751	0.641269137971589
GO:0061775	cohesin loader activity	27/2881	153/18639	0.176470588235294	1.14169916491414	0.256175978905751	0.641269137971589
GO:0046625	sphingolipid binding	6/2881	28/18639	0.214285714285714	1.38634898596717	0.25761676847758	0.641269137971589
GO:0097718	disordered domain specific binding	6/2881	28/18639	0.214285714285714	1.38634898596717	0.25761676847758	0.641269137971589
GO:0141052	histone H3 demethylase activity	6/2881	28/18639	0.214285714285714	1.38634898596717	0.25761676847758	0.641269137971589
GO:0016504	peptidase activator activity	11/2881	57/18639	0.192982456140351	1.24852481777161	0.259211568513734	0.64276306952431
GO:0004549	tRNA-specific ribonuclease activity	4/2881	17/18639	0.235294117647059	1.52226555321886	0.262259459971004	0.64276306952431
GO:0004550	nucleoside diphosphate kinase activity	4/2881	17/18639	0.235294117647059	1.52226555321886	0.262259459971004	0.64276306952431
GO:0004659	prenyltransferase activity	4/2881	17/18639	0.235294117647059	1.52226555321886	0.262259459971004	0.64276306952431
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	4/2881	17/18639	0.235294117647059	1.52226555321886	0.262259459971004	0.64276306952431
GO:0046965	nuclear retinoid X receptor binding	4/2881	17/18639	0.235294117647059	1.52226555321886	0.262259459971004	0.64276306952431
GO:1901567	fatty acid derivative binding	4/2881	17/18639	0.235294117647059	1.52226555321886	0.262259459971004	0.64276306952431
GO:1990226	histone methyltransferase binding	4/2881	17/18639	0.235294117647059	1.52226555321886	0.262259459971004	0.64276306952431
GO:0008376	acetylgalactosaminyltransferase activity	7/2881	34/18639	0.205882352941176	1.3319823590665	0.26554229597413	0.646296798784258
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	7/2881	34/18639	0.205882352941176	1.3319823590665	0.26554229597413	0.646296798784258
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	8/2881	40/18639	0.2	1.29392572023603	0.270905142428087	0.646296798784258
GO:0008168	methyltransferase activity	35/2881	204/18639	0.17156862745098	1.10998529922208	0.276754356325595	0.646296798784258
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	5/2881	23/18639	0.217391304347826	1.40644100025655	0.2770033344795	0.646296798784258
GO:0017134	fibroblast growth factor binding	5/2881	23/18639	0.217391304347826	1.40644100025655	0.2770033344795	0.646296798784258
GO:0043274	phospholipase binding	5/2881	23/18639	0.217391304347826	1.40644100025655	0.2770033344795	0.646296798784258
GO:0140103	catalytic activity, acting on a glycoprotein	5/2881	23/18639	0.217391304347826	1.40644100025655	0.2770033344795	0.646296798784258
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	5/2881	23/18639	0.217391304347826	1.40644100025655	0.2770033344795	0.646296798784258
GO:0008013	beta-catenin binding	19/2881	106/18639	0.179245283018868	1.1596504096455	0.277387727236913	0.646296798784258
GO:0005025	transforming growth factor beta receptor activity, type I	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0005026	transforming growth factor beta receptor activity, type II	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0005078	MAP-kinase scaffold activity	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0005095	GTPase inhibitor activity	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0005165	neurotrophin receptor binding	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0005527	macrolide binding	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0008603	cAMP-dependent protein kinase regulator activity	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0016361	activin receptor activity, type I	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0016362	activin receptor activity, type II	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0017002	activin receptor activity	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0017166	vinculin binding	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0035014	phosphatidylinositol 3-kinase regulator activity	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0035251	UDP-glucosyltransferase activity	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0035497	cAMP response element binding	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0043047	single-stranded telomeric DNA binding	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0070410	co-SMAD binding	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0140829	bicarbonate:monoatomic anion antiporter activity	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0140900	chloride:bicarbonate antiporter activity	3/2881	12/18639	0.25	1.61740715029504	0.279960327146326	0.646296798784258
GO:0106222	lncRNA binding	6/2881	29/18639	0.206896551724138	1.33854384852003	0.285814901015081	0.658281781782687
GO:0016887	ATP hydrolysis activity	69/2881	417/18639	0.165467625899281	1.07051408508736	0.286186969595775	0.658281781782687
GO:0015175	neutral L-amino acid transmembrane transporter activity	8/2881	41/18639	0.195121951219512	1.26236655632783	0.294751272695623	0.675538052015915
GO:0042287	MHC protein binding	8/2881	41/18639	0.195121951219512	1.26236655632783	0.294751272695623	0.675538052015915
GO:0019955	cytokine binding	25/2881	144/18639	0.173611111111111	1.12319940992711	0.295335964240291	0.675660695168435
GO:0061749	forked DNA-dependent helicase activity	9/2881	47/18639	0.191489361702128	1.23886505128982	0.296849013619599	0.677335396068688
GO:0051018	protein kinase A binding	10/2881	53/18639	0.188679245283019	1.2206846417321	0.298016754770281	0.677335396068688
GO:0000900	mRNA regulatory element binding translation repressor activity	4/2881	18/18639	0.222222222222222	1.4376952447067	0.299262965873115	0.677335396068688
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	4/2881	18/18639	0.222222222222222	1.4376952447067	0.299262965873115	0.677335396068688
GO:0035615	clathrin adaptor activity	4/2881	18/18639	0.222222222222222	1.4376952447067	0.299262965873115	0.677335396068688
GO:1901611	phosphatidylglycerol binding	4/2881	18/18639	0.222222222222222	1.4376952447067	0.299262965873115	0.677335396068688
GO:0001965	G-protein alpha-subunit binding	6/2881	30/18639	0.2	1.29392572023603	0.314623854196277	0.709577203080965
GO:0032452	histone demethylase activity	6/2881	30/18639	0.2	1.29392572023603	0.314623854196277	0.709577203080965
GO:0051082	unfolded protein binding	21/2881	121/18639	0.173553719008264	1.12282810433705	0.317042175011026	0.712493377249449
GO:0004869	cysteine-type endopeptidase inhibitor activity	7/2881	36/18639	0.194444444444444	1.25798333911836	0.317597283726759	0.712493377249449
GO:0016409	palmitoyltransferase activity	7/2881	36/18639	0.194444444444444	1.25798333911836	0.317597283726759	0.712493377249449
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	11/2881	60/18639	0.183333333333333	1.18609857688303	0.31874329636552	0.713112515572399
GO:0009378	four-way junction helicase activity	9/2881	48/18639	0.1875	1.21305536272128	0.319555136695179	0.713112515572399
GO:0036121	double-stranded DNA helicase activity	9/2881	48/18639	0.1875	1.21305536272128	0.319555136695179	0.713112515572399
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/2881	13/18639	0.230769230769231	1.49299121565696	0.325439836363834	0.716192857880272
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/2881	13/18639	0.230769230769231	1.49299121565696	0.325439836363834	0.716192857880272
GO:0030955	potassium ion binding	3/2881	13/18639	0.230769230769231	1.49299121565696	0.325439836363834	0.716192857880272
GO:0031432	titin binding	3/2881	13/18639	0.230769230769231	1.49299121565696	0.325439836363834	0.716192857880272
GO:0039706	co-receptor binding	3/2881	13/18639	0.230769230769231	1.49299121565696	0.325439836363834	0.716192857880272
GO:0046974	histone H3K9 methyltransferase activity	3/2881	13/18639	0.230769230769231	1.49299121565696	0.325439836363834	0.716192857880272
GO:0140666	annealing activity	3/2881	13/18639	0.230769230769231	1.49299121565696	0.325439836363834	0.716192857880272
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	3/2881	13/18639	0.230769230769231	1.49299121565696	0.325439836363834	0.716192857880272
GO:0016741	transferase activity, transferring one-carbon groups	36/2881	215/18639	0.167441860465116	1.08328664949993	0.327232778890631	0.718894809583561
GO:0005319	lipid transporter activity	30/2881	178/18639	0.168539325842697	1.09038684289553	0.332414918380552	0.729020303758728
GO:0003756	protein disulfide isomerase activity	4/2881	19/18639	0.210526315789474	1.36202707393266	0.336806590614398	0.730885890353799
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	4/2881	19/18639	0.210526315789474	1.36202707393266	0.336806590614398	0.730885890353799
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	4/2881	19/18639	0.210526315789474	1.36202707393266	0.336806590614398	0.730885890353799
GO:0070003	threonine-type peptidase activity	4/2881	19/18639	0.210526315789474	1.36202707393266	0.336806590614398	0.730885890353799
GO:0097001	ceramide binding	4/2881	19/18639	0.210526315789474	1.36202707393266	0.336806590614398	0.730885890353799
GO:0120227	acyl-CoA binding	4/2881	19/18639	0.210526315789474	1.36202707393266	0.336806590614398	0.730885890353799
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	12/2881	67/18639	0.17910447761194	1.15873945095764	0.337287749715157	0.730885890353799
GO:0015026	coreceptor activity	11/2881	61/18639	0.180327868852459	1.16665433791773	0.339263256522082	0.733916432476341
GO:0004725	protein tyrosine phosphatase activity	17/2881	98/18639	0.173469387755102	1.12228251244962	0.342384685439516	0.735990661873421
GO:0030527	structural constituent of chromatin	17/2881	98/18639	0.173469387755102	1.12228251244962	0.342384685439516	0.735990661873421
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	38/2881	229/18639	0.165938864628821	1.07356282464998	0.342962928085534	0.735990661873421
GO:0004712	protein serine/threonine/tyrosine kinase activity	8/2881	43/18639	0.186046511627907	1.2036518327777	0.343733596155946	0.735990661873421
GO:0005452	solute:inorganic anion antiporter activity	6/2881	31/18639	0.193548387096774	1.25218618087358	0.343853586219681	0.735990661873421
GO:0140457	protein demethylase activity	6/2881	31/18639	0.193548387096774	1.25218618087358	0.343853586219681	0.735990661873421
GO:0030551	cyclic nucleotide binding	7/2881	37/18639	0.189189189189189	1.22398378941246	0.344272361489532	0.735990661873421
GO:0016209	antioxidant activity	15/2881	86/18639	0.174418604651163	1.1284235932291	0.348151536299753	0.743034822438399
GO:0044325	transmembrane transporter binding	23/2881	136/18639	0.169117647058824	1.09412836637605	0.353639938250613	0.753484089538994
GO:0005200	structural constituent of cytoskeleton	19/2881	112/18639	0.169642857142857	1.09752628055735	0.36757168895493	0.774939232369965
GO:0008191	metalloendopeptidase inhibitor activity	3/2881	14/18639	0.214285714285714	1.38634898596717	0.370883385679284	0.774939232369965
GO:0016530	metallochaperone activity	3/2881	14/18639	0.214285714285714	1.38634898596717	0.370883385679284	0.774939232369965
GO:0032454	histone H3K9 demethylase activity	3/2881	14/18639	0.214285714285714	1.38634898596717	0.370883385679284	0.774939232369965
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	3/2881	14/18639	0.214285714285714	1.38634898596717	0.370883385679284	0.774939232369965
GO:0098821	BMP receptor activity	3/2881	14/18639	0.214285714285714	1.38634898596717	0.370883385679284	0.774939232369965
GO:0098847	sequence-specific single stranded DNA binding	3/2881	14/18639	0.214285714285714	1.38634898596717	0.370883385679284	0.774939232369965
GO:0000146	microfilament motor activity	7/2881	38/18639	0.184210526315789	1.19177368969108	0.371191402544705	0.774939232369965
GO:0015106	bicarbonate transmembrane transporter activity	6/2881	32/18639	0.1875	1.21305536272128	0.373319846785135	0.774939232369965
GO:0030515	snoRNA binding	6/2881	32/18639	0.1875	1.21305536272128	0.373319846785135	0.774939232369965
GO:0070717	poly-purine tract binding	6/2881	32/18639	0.1875	1.21305536272128	0.373319846785135	0.774939232369965
GO:0016004	phospholipase activator activity	4/2881	20/18639	0.2	1.29392572023603	0.374501060276515	0.774939232369965
GO:0016505	peptidase activator activity involved in apoptotic process	4/2881	20/18639	0.2	1.29392572023603	0.374501060276515	0.774939232369965
GO:0030742	GTP-dependent protein binding	4/2881	20/18639	0.2	1.29392572023603	0.374501060276515	0.774939232369965
GO:0042288	MHC class I protein binding	4/2881	20/18639	0.2	1.29392572023603	0.374501060276515	0.774939232369965
GO:0008157	protein phosphatase 1 binding	5/2881	26/18639	0.192307692307692	1.2441593463808	0.374675808103403	0.774939232369965
GO:0034237	protein kinase A regulatory subunit binding	5/2881	26/18639	0.192307692307692	1.2441593463808	0.374675808103403	0.774939232369965
GO:0070412	R-SMAD binding	5/2881	26/18639	0.192307692307692	1.2441593463808	0.374675808103403	0.774939232369965
GO:0004601	peroxidase activity	10/2881	57/18639	0.175438596491228	1.13502256161055	0.385052063220039	0.794913186209093
GO:0000510	H3-H4 histone complex chaperone activity	25/2881	151/18639	0.165562913907285	1.0711305631093	0.387457685101916	0.794913186209093
GO:0140584	chromatin extrusion motor activity	25/2881	151/18639	0.165562913907285	1.0711305631093	0.387457685101916	0.794913186209093
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	25/2881	151/18639	0.165562913907285	1.0711305631093	0.387457685101916	0.794913186209093
GO:0140849	ATP-dependent H2AZ histone chaperone activity	25/2881	151/18639	0.165562913907285	1.0711305631093	0.387457685101916	0.794913186209093
GO:0140713	histone chaperone activity	27/2881	164/18639	0.164634146341463	1.06512178190161	0.392588748967668	0.804143137982084
GO:0046915	transition metal ion transmembrane transporter activity	8/2881	45/18639	0.177777777777778	1.15015619576536	0.393696004828039	0.805114659391102
GO:0140658	ATP-dependent chromatin remodeler activity	26/2881	158/18639	0.164556962025316	1.0646224280423	0.396745382241331	0.81004835667893
GO:0015616	DNA translocase activity	25/2881	152/18639	0.164473684210526	1.06408365150989	0.4010366440957	0.813845870965314
GO:0140674	ATP-dependent histone chaperone activity	25/2881	152/18639	0.164473684210526	1.06408365150989	0.4010366440957	0.813845870965314
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	15/2881	89/18639	0.168539325842697	1.09038684289553	0.401164592056016	0.813845870965314
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	15/2881	89/18639	0.168539325842697	1.09038684289553	0.401164592056016	0.813845870965314
GO:0140416	transcription regulator inhibitor activity	6/2881	33/18639	0.181818181818182	1.17629610930548	0.402846812460941	0.815957237978212
GO:0017116	single-stranded DNA helicase activity	10/2881	58/18639	0.172413793103448	1.11545320710003	0.407218227746762	0.822774399926663
GO:0005385	zinc ion transmembrane transporter activity	5/2881	27/18639	0.185185185185185	1.19807937058892	0.407506188642923	0.822774399926663
GO:0016757	glycosyltransferase activity	43/2881	267/18639	0.161048689138577	1.04192520543351	0.409844414658999	0.824931518796879
GO:0003724	RNA helicase activity	13/2881	77/18639	0.168831168831169	1.0922749586408	0.411481379300545	0.824931518796879
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/2881	21/18639	0.19047619047619	1.2323102097486	0.411995102821358	0.824931518796879
GO:0008094	ATP-dependent activity, acting on DNA	34/2881	210/18639	0.161904761904762	1.04746367828631	0.412759534025019	0.824931518796879
GO:0010181	FMN binding	3/2881	15/18639	0.2	1.29392572023603	0.415708414739622	0.824931518796879
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/2881	15/18639	0.2	1.29392572023603	0.415708414739622	0.824931518796879
GO:0016846	carbon-sulfur lyase activity	3/2881	15/18639	0.2	1.29392572023603	0.415708414739622	0.824931518796879
GO:0017081	chloride channel regulator activity	3/2881	15/18639	0.2	1.29392572023603	0.415708414739622	0.824931518796879
GO:0033130	acetylcholine receptor binding	3/2881	15/18639	0.2	1.29392572023603	0.415708414739622	0.824931518796879
GO:0141050	histone H3K deacetylase activity	3/2881	15/18639	0.2	1.29392572023603	0.415708414739622	0.824931518796879
GO:0141051	histone H4K deacetylase activity	3/2881	15/18639	0.2	1.29392572023603	0.415708414739622	0.824931518796879
GO:0140793	histone H2AXY142 phosphatase activity	15/2881	90/18639	0.166666666666667	1.07827143353002	0.41900405229603	0.830176253147274
GO:0003689	DNA clamp loader activity	26/2881	160/18639	0.1625	1.05131464769177	0.423474299907452	0.837728319568086
GO:0032451	demethylase activity	7/2881	40/18639	0.175	1.13218500520653	0.425224619409963	0.839884652002287
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	10/2881	59/18639	0.169491525423729	1.09654722053901	0.429401702190659	0.84682010106437
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	6/2881	34/18639	0.176470588235294	1.14169916491414	0.432269208850973	0.848528447003762
GO:0030332	cyclin binding	6/2881	34/18639	0.176470588235294	1.14169916491414	0.432269208850973	0.848528447003762
GO:0051427	hormone receptor binding	6/2881	34/18639	0.176470588235294	1.14169916491414	0.432269208850973	0.848528447003762
GO:0005544	calcium-dependent phospholipid binding	9/2881	53/18639	0.169811320754717	1.09861617755889	0.43628136857504	0.855084592954469
GO:0051019	mitogen-activated protein kinase binding	5/2881	28/18639	0.178571428571429	1.15529082163931	0.440090845200605	0.861223930915646
GO:0005504	fatty acid binding	8/2881	47/18639	0.170212765957447	1.10121337892428	0.443786793021335	0.866350387203888
GO:0019838	growth factor binding	22/2881	136/18639	0.161764705882353	1.04655756783796	0.444072682749163	0.866350387203888
GO:0004407	histone deacetylase activity	4/2881	22/18639	0.181818181818182	1.17629610930548	0.448978631896165	0.871232039857538
GO:0008970	phospholipase A1 activity	4/2881	22/18639	0.181818181818182	1.17629610930548	0.448978631896165	0.871232039857538
GO:0033558	protein lysine deacetylase activity	4/2881	22/18639	0.181818181818182	1.17629610930548	0.448978631896165	0.871232039857538
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	21/2881	130/18639	0.161538461538462	1.04509385095987	0.449749172507345	0.871232039857538
GO:0008186	ATP-dependent activity, acting on RNA	13/2881	79/18639	0.164556962025316	1.0646224280423	0.449999567756606	0.871232039857538
GO:0001530	lipopolysaccharide binding	7/2881	41/18639	0.170731707317073	1.10457073678685	0.452086779027621	0.871294519580506
GO:0042169	SH2 domain binding	7/2881	41/18639	0.170731707317073	1.10457073678685	0.452086779027621	0.871294519580506
GO:0140828	metal cation:monoatomic cation antiporter activity	7/2881	41/18639	0.170731707317073	1.10457073678685	0.452086779027621	0.871294519580506
GO:0003688	DNA replication origin binding	3/2881	16/18639	0.1875	1.21305536272128	0.459437034608778	0.874727741907742
GO:0005521	lamin binding	3/2881	16/18639	0.1875	1.21305536272128	0.459437034608778	0.874727741907742
GO:0051287	NAD binding	9/2881	54/18639	0.166666666666667	1.07827143353002	0.459661225901285	0.874727741907742
GO:0008173	RNA methyltransferase activity	11/2881	67/18639	0.164179104477612	1.0621778300445	0.465058553903077	0.874727741907742
GO:0050840	extracellular matrix binding	11/2881	67/18639	0.164179104477612	1.0621778300445	0.465058553903077	0.874727741907742
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	5/2881	29/18639	0.172413793103448	1.11545320710003	0.472231666905923	0.874727741907742
GO:0016417	S-acyltransferase activity	5/2881	29/18639	0.172413793103448	1.11545320710003	0.472231666905923	0.874727741907742
GO:0097472	cyclin-dependent protein kinase activity	5/2881	29/18639	0.172413793103448	1.11545320710003	0.472231666905923	0.874727741907742
GO:0001094	TFIID-class transcription factor complex binding	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0004090	carbonyl reductase (NADPH) activity	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0005381	iron ion transmembrane transporter activity	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0016427	tRNA (cytidine) methyltransferase activity	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0030957	Tat protein binding	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0031434	mitogen-activated protein kinase kinase binding	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0042975	peroxisome proliferator activated receptor binding	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0043422	protein kinase B binding	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0045322	unmethylated CpG binding	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0098505	G-rich strand telomeric DNA binding	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0140940	histone H2A methyltransferase activity	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:1990259	histone H2AQ104 methyltransferase activity	2/2881	10/18639	0.2	1.29392572023603	0.472435502115266	0.874727741907742
GO:0003678	DNA helicase activity	12/2881	74/18639	0.162162162162162	1.04912896235354	0.477220657360312	0.882303308375461
GO:0008081	phosphoric diester hydrolase activity	14/2881	87/18639	0.160919540229885	1.04108965996002	0.480129296788424	0.886392547917091
GO:0003887	DNA-directed DNA polymerase activity	4/2881	23/18639	0.173913043478261	1.12515280020524	0.485183957668095	0.893131684737795
GO:0031681	G-protein beta-subunit binding	4/2881	23/18639	0.173913043478261	1.12515280020524	0.485183957668095	0.893131684737795
GO:0016758	hexosyltransferase activity	31/2881	197/18639	0.157360406091371	1.01806338394205	0.487102852585165	0.895368249260593
GO:0045505	dynein intermediate chain binding	6/2881	36/18639	0.166666666666667	1.07827143353002	0.490201273855761	0.899763377120531
GO:0016763	pentosyltransferase activity	8/2881	49/18639	0.163265306122449	1.05626589407023	0.493226275800598	0.904011272072565
GO:0015179	L-amino acid transmembrane transporter activity	10/2881	62/18639	0.161290322580645	1.04348848406131	0.495380204045224	0.905175718047707
GO:0005092	GDP-dissociation inhibitor activity	3/2881	17/18639	0.176470588235294	1.14169916491414	0.501689372031158	0.905175718047707
GO:0016018	cyclosporin A binding	3/2881	17/18639	0.176470588235294	1.14169916491414	0.501689372031158	0.905175718047707
GO:0017110	nucleoside diphosphate phosphatase activity	3/2881	17/18639	0.176470588235294	1.14169916491414	0.501689372031158	0.905175718047707
GO:0036041	long-chain fatty acid binding	3/2881	17/18639	0.176470588235294	1.14169916491414	0.501689372031158	0.905175718047707
GO:0038191	neuropilin binding	3/2881	17/18639	0.176470588235294	1.14169916491414	0.501689372031158	0.905175718047707
GO:0045236	CXCR chemokine receptor binding	3/2881	17/18639	0.176470588235294	1.14169916491414	0.501689372031158	0.905175718047707
GO:0048038	quinone binding	3/2881	17/18639	0.176470588235294	1.14169916491414	0.501689372031158	0.905175718047707
GO:0070402	NADPH binding	3/2881	17/18639	0.176470588235294	1.14169916491414	0.501689372031158	0.905175718047707
GO:0070403	NAD+ binding	3/2881	17/18639	0.176470588235294	1.14169916491414	0.501689372031158	0.905175718047707
GO:0070492	oligosaccharide binding	3/2881	17/18639	0.176470588235294	1.14169916491414	0.501689372031158	0.905175718047707
GO:0051087	protein-folding chaperone binding	21/2881	134/18639	0.156716417910448	1.01389701958793	0.509368397860628	0.917602925029698
GO:0019213	deacetylase activity	6/2881	37/18639	0.162162162162162	1.04912896235354	0.518445579475031	0.917602925029698
GO:0023023	MHC protein complex binding	6/2881	37/18639	0.162162162162162	1.04912896235354	0.518445579475031	0.917602925029698
GO:0005315	phosphate transmembrane transporter activity	4/2881	24/18639	0.166666666666667	1.07827143353002	0.520385449163209	0.917602925029698
GO:0042625	ATPase-coupled ion transmembrane transporter activity	4/2881	24/18639	0.166666666666667	1.07827143353002	0.520385449163209	0.917602925029698
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	4/2881	24/18639	0.166666666666667	1.07827143353002	0.520385449163209	0.917602925029698
GO:0046961	proton-transporting ATPase activity, rotational mechanism	4/2881	24/18639	0.166666666666667	1.07827143353002	0.520385449163209	0.917602925029698
GO:0048027	mRNA 5'-UTR binding	4/2881	24/18639	0.166666666666667	1.07827143353002	0.520385449163209	0.917602925029698
GO:0050431	transforming growth factor beta binding	4/2881	24/18639	0.166666666666667	1.07827143353002	0.520385449163209	0.917602925029698
GO:0060229	lipase activator activity	4/2881	24/18639	0.166666666666667	1.07827143353002	0.520385449163209	0.917602925029698
GO:0070840	dynein complex binding	4/2881	24/18639	0.166666666666667	1.07827143353002	0.520385449163209	0.917602925029698
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/2881	11/18639	0.181818181818182	1.17629610930548	0.525168969671085	0.917602925029698
GO:0005114	type II transforming growth factor beta receptor binding	2/2881	11/18639	0.181818181818182	1.17629610930548	0.525168969671085	0.917602925029698
GO:0005225	volume-sensitive anion channel activity	2/2881	11/18639	0.181818181818182	1.17629610930548	0.525168969671085	0.917602925029698
GO:0008172	S-methyltransferase activity	2/2881	11/18639	0.181818181818182	1.17629610930548	0.525168969671085	0.917602925029698
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/2881	11/18639	0.181818181818182	1.17629610930548	0.525168969671085	0.917602925029698
GO:0032794	GTPase activating protein binding	2/2881	11/18639	0.181818181818182	1.17629610930548	0.525168969671085	0.917602925029698
GO:0043522	leucine zipper domain binding	2/2881	11/18639	0.181818181818182	1.17629610930548	0.525168969671085	0.917602925029698
GO:0045294	alpha-catenin binding	2/2881	11/18639	0.181818181818182	1.17629610930548	0.525168969671085	0.917602925029698
GO:0050998	nitric-oxide synthase binding	2/2881	11/18639	0.181818181818182	1.17629610930548	0.525168969671085	0.917602925029698
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/2881	11/18639	0.181818181818182	1.17629610930548	0.525168969671085	0.917602925029698
GO:0140031	phosphorylation-dependent protein binding	2/2881	11/18639	0.181818181818182	1.17629610930548	0.525168969671085	0.917602925029698
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/2881	11/18639	0.181818181818182	1.17629610930548	0.525168969671085	0.917602925029698
GO:0008327	methyl-CpG binding	5/2881	31/18639	0.161290322580645	1.04348848406131	0.534503160837886	0.93007937152639
GO:0016878	acid-thiol ligase activity	5/2881	31/18639	0.161290322580645	1.04348848406131	0.534503160837886	0.93007937152639
GO:0070273	phosphatidylinositol-4-phosphate binding	5/2881	31/18639	0.161290322580645	1.04348848406131	0.534503160837886	0.93007937152639
GO:0008308	voltage-gated monoatomic anion channel activity	3/2881	18/18639	0.166666666666667	1.07827143353002	0.542174653262767	0.935747841180787
GO:0008409	5'-3' exonuclease activity	3/2881	18/18639	0.166666666666667	1.07827143353002	0.542174653262767	0.935747841180787
GO:0015172	acidic amino acid transmembrane transporter activity	3/2881	18/18639	0.166666666666667	1.07827143353002	0.542174653262767	0.935747841180787
GO:0017075	syntaxin-1 binding	3/2881	18/18639	0.166666666666667	1.07827143353002	0.542174653262767	0.935747841180787
GO:0031690	adrenergic receptor binding	3/2881	18/18639	0.166666666666667	1.07827143353002	0.542174653262767	0.935747841180787
GO:0050811	GABA receptor binding	3/2881	18/18639	0.166666666666667	1.07827143353002	0.542174653262767	0.935747841180787
GO:0043531	ADP binding	6/2881	38/18639	0.157894736842105	1.0215203054495	0.546055737649467	0.941169238875504
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	14/2881	91/18639	0.153846153846154	0.995327477104638	0.552328834691812	0.949117478780489
GO:0008483	transaminase activity	4/2881	25/18639	0.16	1.03514057618882	0.554398024161874	0.949117478780489
GO:0019706	protein-cysteine S-palmitoyltransferase activity	4/2881	25/18639	0.16	1.03514057618882	0.554398024161874	0.949117478780489
GO:0019707	protein-cysteine S-acyltransferase activity	4/2881	25/18639	0.16	1.03514057618882	0.554398024161874	0.949117478780489
GO:0120020	cholesterol transfer activity	4/2881	25/18639	0.16	1.03514057618882	0.554398024161874	0.949117478780489
GO:0031369	translation initiation factor binding	5/2881	32/18639	0.15625	1.0108794689344	0.564351922699506	0.959784504704229
GO:0005080	protein kinase C binding	8/2881	52/18639	0.153846153846154	0.995327477104638	0.564700227777843	0.959784504704229
GO:0052689	carboxylic ester hydrolase activity	14/2881	92/18639	0.152173913043478	0.984508700179587	0.569849629064851	0.959784504704229
GO:0004879	nuclear receptor activity	9/2881	59/18639	0.152542372881356	0.986892498485107	0.572579500256891	0.959784504704229
GO:0070888	E-box binding	9/2881	59/18639	0.152542372881356	0.986892498485107	0.572579500256891	0.959784504704229
GO:0008194	UDP-glycosyltransferase activity	22/2881	145/18639	0.151724137931034	0.981598822248022	0.573395980141903	0.959784504704229
GO:0000995	RNA polymerase III general transcription initiation factor activity	2/2881	12/18639	0.166666666666667	1.07827143353002	0.574210698176037	0.959784504704229
GO:0004000	adenosine deaminase activity	2/2881	12/18639	0.166666666666667	1.07827143353002	0.574210698176037	0.959784504704229
GO:0015132	prostaglandin transmembrane transporter activity	2/2881	12/18639	0.166666666666667	1.07827143353002	0.574210698176037	0.959784504704229
GO:0015368	calcium:monoatomic cation antiporter activity	2/2881	12/18639	0.166666666666667	1.07827143353002	0.574210698176037	0.959784504704229
GO:0016208	AMP binding	2/2881	12/18639	0.166666666666667	1.07827143353002	0.574210698176037	0.959784504704229
GO:0035259	nuclear glucocorticoid receptor binding	2/2881	12/18639	0.166666666666667	1.07827143353002	0.574210698176037	0.959784504704229
GO:0036009	protein-glutamine N-methyltransferase activity	2/2881	12/18639	0.166666666666667	1.07827143353002	0.574210698176037	0.959784504704229
GO:0045295	gamma-catenin binding	2/2881	12/18639	0.166666666666667	1.07827143353002	0.574210698176037	0.959784504704229
GO:0097677	STAT family protein binding	2/2881	12/18639	0.166666666666667	1.07827143353002	0.574210698176037	0.959784504704229
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/2881	12/18639	0.166666666666667	1.07827143353002	0.574210698176037	0.959784504704229
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/2881	12/18639	0.166666666666667	1.07827143353002	0.574210698176037	0.959784504704229
GO:1990459	transferrin receptor binding	2/2881	12/18639	0.166666666666667	1.07827143353002	0.574210698176037	0.959784504704229
GO:0008301	DNA binding, bending	3/2881	19/18639	0.157894736842105	1.0215203054495	0.580681165009336	0.964264284454146
GO:0016918	retinal binding	3/2881	19/18639	0.157894736842105	1.0215203054495	0.580681165009336	0.964264284454146
GO:0022821	solute:potassium antiporter activity	3/2881	19/18639	0.157894736842105	1.0215203054495	0.580681165009336	0.964264284454146
GO:0031420	alkali metal ion binding	3/2881	19/18639	0.157894736842105	1.0215203054495	0.580681165009336	0.964264284454146
GO:0046527	glucosyltransferase activity	3/2881	19/18639	0.157894736842105	1.0215203054495	0.580681165009336	0.964264284454146
GO:0004521	RNA endonuclease activity	11/2881	73/18639	0.150684931506849	0.974875542643583	0.586454710079601	0.966093942838385
GO:0008143	poly(A) binding	4/2881	26/18639	0.153846153846154	0.995327477104638	0.587074790717959	0.966093942838385
GO:0015216	purine nucleotide transmembrane transporter activity	4/2881	26/18639	0.153846153846154	0.995327477104638	0.587074790717959	0.966093942838385
GO:0030507	spectrin binding	4/2881	26/18639	0.153846153846154	0.995327477104638	0.587074790717959	0.966093942838385
GO:0051139	metal cation:proton antiporter activity	4/2881	26/18639	0.153846153846154	0.995327477104638	0.587074790717959	0.966093942838385
GO:0097602	cullin family protein binding	4/2881	26/18639	0.153846153846154	0.995327477104638	0.587074790717959	0.966093942838385
GO:0051213	dioxygenase activity	14/2881	93/18639	0.150537634408602	0.973922585123893	0.58709954230666	0.966093942838385
GO:0030296	protein tyrosine kinase activator activity	5/2881	33/18639	0.151515151515152	0.980246757754567	0.593192120956393	0.973572702823681
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	9/2881	60/18639	0.15	0.970444290177022	0.593940579710044	0.973572702823681
GO:0098531	ligand-modulated transcription factor activity	9/2881	60/18639	0.15	0.970444290177022	0.593940579710044	0.973572702823681
GO:0061134	peptidase regulator activity	34/2881	226/18639	0.150442477876106	0.973306957699668	0.596999038443015	0.977326611196287
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	6/2881	40/18639	0.15	0.970444290177022	0.59900176957651	0.979344795502982
GO:0004175	endopeptidase activity	61/2881	405/18639	0.150617283950617	0.974437888078985	0.609389500957591	0.993118214784007
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	8/2881	54/18639	0.148148148148148	0.958463496471133	0.609768337850872	0.993118214784007
GO:0050661	NADP binding	8/2881	54/18639	0.148148148148148	0.958463496471133	0.609768337850872	0.993118214784007
GO:0015095	magnesium ion transmembrane transporter activity	3/2881	20/18639	0.15	0.970444290177022	0.617065889373952	0.997379650325586
GO:0015297	antiporter activity	20/2881	135/18639	0.148148148148148	0.958463496471133	0.61859757739248	0.997379650325586
GO:0017154	semaphorin receptor activity	2/2881	13/18639	0.153846153846154	0.995327477104638	0.619441763960073	0.997379650325586
GO:0035673	oligopeptide transmembrane transporter activity	2/2881	13/18639	0.153846153846154	0.995327477104638	0.619441763960073	0.997379650325586
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/2881	13/18639	0.153846153846154	0.995327477104638	0.619441763960073	0.997379650325586
GO:0045159	myosin II binding	2/2881	13/18639	0.153846153846154	0.995327477104638	0.619441763960073	0.997379650325586
GO:0061459	L-arginine transmembrane transporter activity	2/2881	13/18639	0.153846153846154	0.995327477104638	0.619441763960073	0.997379650325586
GO:0070700	BMP receptor binding	2/2881	13/18639	0.153846153846154	0.995327477104638	0.619441763960073	0.997379650325586
GO:0071714	icosanoid transmembrane transporter activity	2/2881	13/18639	0.153846153846154	0.995327477104638	0.619441763960073	0.997379650325586
GO:0016879	ligase activity, forming carbon-nitrogen bonds	7/2881	48/18639	0.145833333333333	0.943487504338771	0.627718468683697	1
GO:0043015	gamma-tubulin binding	5/2881	35/18639	0.142857142857143	0.924232657311449	0.647521368706766	1
GO:0051959	dynein light intermediate chain binding	4/2881	28/18639	0.142857142857143	0.924232657311449	0.648006324087526	1
GO:0051879	Hsp90 protein binding	6/2881	42/18639	0.142857142857143	0.924232657311449	0.648436532158411	1
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	3/2881	21/18639	0.142857142857143	0.924232657311449	0.651244353799385	1
GO:0005123	death receptor binding	3/2881	21/18639	0.142857142857143	0.924232657311449	0.651244353799385	1
GO:0010314	phosphatidylinositol-5-phosphate binding	3/2881	21/18639	0.142857142857143	0.924232657311449	0.651244353799385	1
GO:0015174	basic amino acid transmembrane transporter activity	3/2881	21/18639	0.142857142857143	0.924232657311449	0.651244353799385	1
GO:0036122	BMP binding	3/2881	21/18639	0.142857142857143	0.924232657311449	0.651244353799385	1
GO:0051428	peptide hormone receptor binding	3/2881	21/18639	0.142857142857143	0.924232657311449	0.651244353799385	1
GO:1904047	S-adenosyl-L-methionine binding	3/2881	21/18639	0.142857142857143	0.924232657311449	0.651244353799385	1
GO:1902936	phosphatidylinositol bisphosphate binding	16/2881	111/18639	0.144144144144144	0.932559077647588	0.659603242744724	1
GO:0004065	arylsulfatase activity	2/2881	14/18639	0.142857142857143	0.924232657311449	0.660868160340205	1
GO:0005161	platelet-derived growth factor receptor binding	2/2881	14/18639	0.142857142857143	0.924232657311449	0.660868160340205	1
GO:0005313	L-glutamate transmembrane transporter activity	2/2881	14/18639	0.142857142857143	0.924232657311449	0.660868160340205	1
GO:0005347	ATP transmembrane transporter activity	2/2881	14/18639	0.142857142857143	0.924232657311449	0.660868160340205	1
GO:0008331	high voltage-gated calcium channel activity	2/2881	14/18639	0.142857142857143	0.924232657311449	0.660868160340205	1
GO:0008474	palmitoyl-(protein) hydrolase activity	2/2881	14/18639	0.142857142857143	0.924232657311449	0.660868160340205	1
GO:0008559	ABC-type xenobiotic transporter activity	2/2881	14/18639	0.142857142857143	0.924232657311449	0.660868160340205	1
GO:0015386	potassium:proton antiporter activity	2/2881	14/18639	0.142857142857143	0.924232657311449	0.660868160340205	1
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/2881	14/18639	0.142857142857143	0.924232657311449	0.660868160340205	1
GO:0061783	peptidoglycan muralytic activity	2/2881	14/18639	0.142857142857143	0.924232657311449	0.660868160340205	1
GO:0098599	palmitoyl hydrolase activity	2/2881	14/18639	0.142857142857143	0.924232657311449	0.660868160340205	1
GO:1901474	azole transmembrane transporter activity	2/2881	14/18639	0.142857142857143	0.924232657311449	0.660868160340205	1
GO:1901612	cardiolipin binding	2/2881	14/18639	0.142857142857143	0.924232657311449	0.660868160340205	1
GO:0072341	modified amino acid binding	13/2881	91/18639	0.142857142857143	0.924232657311449	0.665639746139206	1
GO:0042626	ATPase-coupled transmembrane transporter activity	14/2881	98/18639	0.142857142857143	0.924232657311449	0.668452975770701	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6/2881	43/18639	0.13953488372093	0.902738874583276	0.671707385639549	1
GO:0015605	organophosphate ester transmembrane transporter activity	7/2881	50/18639	0.14	0.90574800416522	0.671727982444357	1
GO:0070851	growth factor receptor binding	20/2881	139/18639	0.143884892086331	0.930881813119445	0.672217928567606	1
GO:0008093	cytoskeletal anchor activity	3/2881	22/18639	0.136363636363636	0.882222081979111	0.683181046731472	1
GO:0008649	rRNA methyltransferase activity	3/2881	22/18639	0.136363636363636	0.882222081979111	0.683181046731472	1
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	3/2881	22/18639	0.136363636363636	0.882222081979111	0.683181046731472	1
GO:0031683	G-protein beta/gamma-subunit complex binding	3/2881	22/18639	0.136363636363636	0.882222081979111	0.683181046731472	1
GO:0061133	endopeptidase activator activity	3/2881	22/18639	0.136363636363636	0.882222081979111	0.683181046731472	1
GO:0005126	cytokine receptor binding	40/2881	275/18639	0.145454545454545	0.941036887444385	0.688286150881884	1
GO:0160215	deacylase activity	9/2881	65/18639	0.138461538461538	0.895794729394174	0.692202232315216	1
GO:0016597	amino acid binding	7/2881	51/18639	0.137254901960784	0.887988239377667	0.692472902474192	1
GO:0030544	Hsp70 protein binding	7/2881	51/18639	0.137254901960784	0.887988239377667	0.692472902474192	1
GO:0005178	integrin binding	23/2881	161/18639	0.142857142857143	0.924232657311449	0.692819190560742	1
GO:0042379	chemokine receptor binding	10/2881	72/18639	0.138888888888889	0.898559527941687	0.692896709910931	1
GO:0016790	thiolester hydrolase activity	6/2881	44/18639	0.136363636363636	0.882222081979111	0.6939690587297	1
GO:0000774	adenyl-nucleotide exchange factor activity	2/2881	15/18639	0.133333333333333	0.862617146824019	0.698585044278756	1
GO:0004089	carbonate dehydratase activity	2/2881	15/18639	0.133333333333333	0.862617146824019	0.698585044278756	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/2881	15/18639	0.133333333333333	0.862617146824019	0.698585044278756	1
GO:0005523	tropomyosin binding	2/2881	15/18639	0.133333333333333	0.862617146824019	0.698585044278756	1
GO:0015929	hexosaminidase activity	2/2881	15/18639	0.133333333333333	0.862617146824019	0.698585044278756	1
GO:0045504	dynein heavy chain binding	2/2881	15/18639	0.133333333333333	0.862617146824019	0.698585044278756	1
GO:0050780	dopamine receptor binding	2/2881	15/18639	0.133333333333333	0.862617146824019	0.698585044278756	1
GO:0004518	nuclease activity	30/2881	209/18639	0.143540669856459	0.928654823135906	0.699876904076705	1
GO:0015215	nucleotide transmembrane transporter activity	4/2881	30/18639	0.133333333333333	0.862617146824019	0.702649813819464	1
GO:0016769	transferase activity, transferring nitrogenous groups	4/2881	30/18639	0.133333333333333	0.862617146824019	0.702649813819464	1
GO:0035925	mRNA 3'-UTR AU-rich region binding	4/2881	30/18639	0.133333333333333	0.862617146824019	0.702649813819464	1
GO:0098918	structural constituent of synapse	4/2881	30/18639	0.133333333333333	0.862617146824019	0.702649813819464	1
GO:0000295	adenine nucleotide transmembrane transporter activity	3/2881	23/18639	0.130434782608696	0.843864600153932	0.712880610090978	1
GO:0005212	structural constituent of eye lens	3/2881	23/18639	0.130434782608696	0.843864600153932	0.712880610090978	1
GO:0008171	O-methyltransferase activity	3/2881	23/18639	0.130434782608696	0.843864600153932	0.712880610090978	1
GO:0016493	C-C chemokine receptor activity	3/2881	23/18639	0.130434782608696	0.843864600153932	0.712880610090978	1
GO:0042171	lysophosphatidic acid acyltransferase activity	3/2881	23/18639	0.130434782608696	0.843864600153932	0.712880610090978	1
GO:0071617	lysophospholipid acyltransferase activity	3/2881	23/18639	0.130434782608696	0.843864600153932	0.712880610090978	1
GO:0099186	structural constituent of postsynapse	3/2881	23/18639	0.130434782608696	0.843864600153932	0.712880610090978	1
GO:0140102	catalytic activity, acting on a rRNA	3/2881	23/18639	0.130434782608696	0.843864600153932	0.712880610090978	1
GO:0042887	amide transmembrane transporter activity	5/2881	38/18639	0.131578947368421	0.851266921207914	0.719903034011681	1
GO:0001618	virus receptor activity	11/2881	81/18639	0.135802469135802	0.878591538431872	0.725679728520165	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/2881	31/18639	0.129032258064516	0.834790787249051	0.727560429075993	1
GO:0047499	calcium-independent phospholipase A2 activity	4/2881	31/18639	0.129032258064516	0.834790787249051	0.727560429075993	1
GO:0072349	modified amino acid transmembrane transporter activity	4/2881	31/18639	0.129032258064516	0.834790787249051	0.727560429075993	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/2881	16/18639	0.125	0.808703575147518	0.732749045660181	1
GO:0015385	sodium:proton antiporter activity	2/2881	16/18639	0.125	0.808703575147518	0.732749045660181	1
GO:0019841	retinol binding	2/2881	16/18639	0.125	0.808703575147518	0.732749045660181	1
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/2881	16/18639	0.125	0.808703575147518	0.732749045660181	1
GO:0070411	I-SMAD binding	2/2881	16/18639	0.125	0.808703575147518	0.732749045660181	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	6/2881	46/18639	0.130434782608696	0.843864600153932	0.735394891036209	1
GO:0033218	amide binding	35/2881	247/18639	0.1417004048583	0.916748992070061	0.738968948028637	1
GO:0004622	lysophospholipase activity	3/2881	24/18639	0.125	0.808703575147518	0.740379918794945	1
GO:0019957	C-C chemokine binding	3/2881	24/18639	0.125	0.808703575147518	0.740379918794945	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	3/2881	24/18639	0.125	0.808703575147518	0.740379918794945	1
GO:0140612	DNA damage sensor activity	3/2881	24/18639	0.125	0.808703575147518	0.740379918794945	1
GO:0140272	exogenous protein binding	11/2881	82/18639	0.134146341463415	0.867877007475385	0.740721148686261	1
GO:0044183	protein folding chaperone	10/2881	75/18639	0.133333333333333	0.862617146824019	0.741762555693076	1
GO:0031072	heat shock protein binding	18/2881	131/18639	0.137404580152672	0.888956601688875	0.742454463229719	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/2881	32/18639	0.125	0.808703575147518	0.75087592998692	1
GO:0042910	xenobiotic transmembrane transporter activity	4/2881	32/18639	0.125	0.808703575147518	0.75087592998692	1
GO:0043425	bHLH transcription factor binding	4/2881	32/18639	0.125	0.808703575147518	0.75087592998692	1
GO:0047498	calcium-dependent phospholipase A2 activity	4/2881	32/18639	0.125	0.808703575147518	0.75087592998692	1
GO:0001540	amyloid-beta binding	11/2881	83/18639	0.132530120481928	0.85742065798773	0.755202274532703	1
GO:0042277	peptide binding	35/2881	249/18639	0.140562248995984	0.909385546350623	0.756047572418518	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/2881	17/18639	0.117647058823529	0.761132776609429	0.763557002144051	1
GO:0008484	sulfuric ester hydrolase activity	2/2881	17/18639	0.117647058823529	0.761132776609429	0.763557002144051	1
GO:0015278	intracellularly gated calcium channel activity	2/2881	17/18639	0.117647058823529	0.761132776609429	0.763557002144051	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/2881	17/18639	0.117647058823529	0.761132776609429	0.763557002144051	1
GO:0016805	dipeptidase activity	2/2881	17/18639	0.117647058823529	0.761132776609429	0.763557002144051	1
GO:0030169	low-density lipoprotein particle binding	2/2881	17/18639	0.117647058823529	0.761132776609429	0.763557002144051	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/2881	17/18639	0.117647058823529	0.761132776609429	0.763557002144051	1
GO:0045125	bioactive lipid receptor activity	2/2881	17/18639	0.117647058823529	0.761132776609429	0.763557002144051	1
GO:0005537	D-mannose binding	3/2881	25/18639	0.12	0.776355432141617	0.76574108624491	1
GO:0015662	P-type ion transporter activity	3/2881	25/18639	0.12	0.776355432141617	0.76574108624491	1
GO:0047617	fatty acyl-CoA hydrolase activity	3/2881	25/18639	0.12	0.776355432141617	0.76574108624491	1
GO:0140358	P-type transmembrane transporter activity	3/2881	25/18639	0.12	0.776355432141617	0.76574108624491	1
GO:0098632	cell-cell adhesion mediator activity	7/2881	55/18639	0.127272727272727	0.823407276513837	0.766669705194823	1
GO:0030414	peptidase inhibitor activity	23/2881	169/18639	0.136094674556213	0.88048199897718	0.777723625810834	1
GO:0005507	copper ion binding	8/2881	63/18639	0.126984126984127	0.821540139832399	0.777951248217508	1
GO:1901682	sulfur compound transmembrane transporter activity	8/2881	63/18639	0.126984126984127	0.821540139832399	0.777951248217508	1
GO:0001637	G protein-coupled chemoattractant receptor activity	3/2881	26/18639	0.115384615384615	0.746495607828478	0.789045385661468	1
GO:0004950	chemokine receptor activity	3/2881	26/18639	0.115384615384615	0.746495607828478	0.789045385661468	1
GO:0008198	ferrous iron binding	3/2881	26/18639	0.115384615384615	0.746495607828478	0.789045385661468	1
GO:0015145	monosaccharide transmembrane transporter activity	3/2881	26/18639	0.115384615384615	0.746495607828478	0.789045385661468	1
GO:0016289	acyl-CoA hydrolase activity	3/2881	26/18639	0.115384615384615	0.746495607828478	0.789045385661468	1
GO:0070006	metalloaminopeptidase activity	3/2881	26/18639	0.115384615384615	0.746495607828478	0.789045385661468	1
GO:0035254	glutamate receptor binding	6/2881	49/18639	0.122448979591837	0.792199420552671	0.789763474695644	1
GO:0060590	ATPase regulator activity	6/2881	49/18639	0.122448979591837	0.792199420552671	0.789763474695644	1
GO:0003746	translation elongation factor activity	2/2881	18/18639	0.111111111111111	0.71884762235335	0.791229795754211	1
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/2881	18/18639	0.111111111111111	0.71884762235335	0.791229795754211	1
GO:0017128	phospholipid scramblase activity	2/2881	18/18639	0.111111111111111	0.71884762235335	0.791229795754211	1
GO:0032393	MHC class I receptor activity	2/2881	18/18639	0.111111111111111	0.71884762235335	0.791229795754211	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	11/2881	86/18639	0.127906976744186	0.82751063503467	0.79527073758431	1
GO:0019842	vitamin binding	20/2881	150/18639	0.133333333333333	0.862617146824019	0.796203833598067	1
GO:0033293	monocarboxylic acid binding	10/2881	79/18639	0.126582278481013	0.81894032926331	0.798300869477878	1
GO:0015932	nucleobase-containing compound transmembrane transporter activity	7/2881	57/18639	0.12280701754386	0.794515793127386	0.798479249813149	1
GO:0008307	structural constituent of muscle	5/2881	42/18639	0.119047619047619	0.770193881092874	0.798912214421524	1
GO:0042056	chemoattractant activity	5/2881	42/18639	0.119047619047619	0.770193881092874	0.798912214421524	1
GO:0016829	lyase activity	27/2881	200/18639	0.135	0.87339986115932	0.805866206519316	1
GO:0001671	ATPase activator activity	3/2881	27/18639	0.111111111111111	0.71884762235335	0.810388044766906	1
GO:0004683	calcium/calmodulin-dependent protein kinase activity	3/2881	27/18639	0.111111111111111	0.71884762235335	0.810388044766906	1
GO:0016405	CoA-ligase activity	3/2881	27/18639	0.111111111111111	0.71884762235335	0.810388044766906	1
GO:0004623	phospholipase A2 activity	4/2881	35/18639	0.114285714285714	0.739386125849159	0.81160262744448	1
GO:0016229	steroid dehydrogenase activity	4/2881	35/18639	0.114285714285714	0.739386125849159	0.81160262744448	1
GO:0034061	DNA polymerase activity	4/2881	35/18639	0.114285714285714	0.739386125849159	0.81160262744448	1
GO:0000182	rDNA binding	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0003796	lysozyme activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0004382	GDP phosphatase activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0004955	prostaglandin receptor activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0008239	dipeptidyl-peptidase activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0008519	ammonium channel activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0015187	glycine transmembrane transporter activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0015279	store-operated calcium channel activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0015643	toxic substance binding	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0016783	sulfurtransferase activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0016868	intramolecular phosphotransferase activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0019531	oxalate transmembrane transporter activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0019911	structural constituent of myelin sheath	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0031720	haptoglobin binding	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0032356	oxidized DNA binding	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0035256	G protein-coupled glutamate receptor binding	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0035374	chondroitin sulfate binding	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0043121	neurotrophin binding	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0043208	glycosphingolipid binding	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0043295	glutathione binding	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0050308	sugar-phosphatase activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0070739	protein-glutamic acid ligase activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0070740	tubulin-glutamic acid ligase activity	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0097177	mitochondrial ribosome binding	1/2881	10/18639	0.1	0.646962860118015	0.813536810135176	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/2881	19/18639	0.105263157894737	0.681013536966331	0.816000222900667	1
GO:0005229	intracellularly calcium-gated chloride channel activity	2/2881	19/18639	0.105263157894737	0.681013536966331	0.816000222900667	1
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/2881	19/18639	0.105263157894737	0.681013536966331	0.816000222900667	1
GO:0042834	peptidoglycan binding	2/2881	19/18639	0.105263157894737	0.681013536966331	0.816000222900667	1
GO:0141147	intracellularly calcium-gated channel activity	2/2881	19/18639	0.105263157894737	0.681013536966331	0.816000222900667	1
GO:0008235	metalloexopeptidase activity	8/2881	66/18639	0.121212121212121	0.784197406203654	0.820334507549969	1
GO:0015101	organic cation transmembrane transporter activity	10/2881	81/18639	0.123456790123457	0.79871958039261	0.822906714045211	1
GO:0015459	potassium channel regulator activity	7/2881	59/18639	0.11864406779661	0.767583054377305	0.82687582100134	1
GO:0004190	aspartic-type endopeptidase activity	4/2881	36/18639	0.111111111111111	0.71884762235335	0.828941008680827	1
GO:0050698	proteoglycan sulfotransferase activity	3/2881	28/18639	0.107142857142857	0.693174492983587	0.829873851248432	1
GO:0051119	sugar transmembrane transporter activity	3/2881	28/18639	0.107142857142857	0.693174492983587	0.829873851248432	1
GO:0004866	endopeptidase inhibitor activity	21/2881	161/18639	0.130434782608696	0.843864600153932	0.831221410261321	1
GO:0030547	signaling receptor inhibitor activity	5/2881	44/18639	0.113636363636364	0.735185068315926	0.831249773067598	1
GO:0001614	purinergic nucleotide receptor activity	2/2881	20/18639	0.1	0.646962860118015	0.838104037736969	1
GO:0016502	nucleotide receptor activity	2/2881	20/18639	0.1	0.646962860118015	0.838104037736969	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	2/2881	20/18639	0.1	0.646962860118015	0.838104037736969	1
GO:0031418	L-ascorbic acid binding	2/2881	20/18639	0.1	0.646962860118015	0.838104037736969	1
GO:0043024	ribosomal small subunit binding	2/2881	20/18639	0.1	0.646962860118015	0.838104037736969	1
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0001851	complement component C3b binding	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0003953	NAD+ nucleosidase activity	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0004954	prostanoid receptor activity	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0008046	axon guidance receptor activity	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0008271	secondary active sulfate transmembrane transporter activity	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0008503	benzodiazepine receptor activity	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0010854	adenylate cyclase regulator activity	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0015217	ADP transmembrane transporter activity	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0019203	carbohydrate phosphatase activity	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0047676	arachidonate-CoA ligase activity	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0048407	platelet-derived growth factor binding	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0070697	activin receptor binding	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0140537	transcription regulator activator activity	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:1900750	oligopeptide binding	1/2881	11/18639	0.0909090909090909	0.588148054652741	0.842373594181586	1
GO:0061135	endopeptidase regulator activity	24/2881	184/18639	0.130434782608696	0.843864600153932	0.844706353363639	1
GO:0030145	manganese ion binding	8/2881	68/18639	0.117647058823529	0.761132776609429	0.844928839723669	1
GO:0043394	proteoglycan binding	4/2881	37/18639	0.108108108108108	0.699419308235691	0.844930417035655	1
GO:0070001	aspartic-type peptidase activity	4/2881	37/18639	0.108108108108108	0.699419308235691	0.844930417035655	1
GO:0008009	chemokine activity	5/2881	45/18639	0.111111111111111	0.71884762235335	0.845755793158196	1
GO:0004629	phospholipase C activity	3/2881	29/18639	0.103448275862069	0.669271924260015	0.847613495326722	1
GO:0051861	glycolipid binding	3/2881	29/18639	0.103448275862069	0.669271924260015	0.847613495326722	1
GO:0016860	intramolecular oxidoreductase activity	6/2881	53/18639	0.113207547169811	0.732410785039262	0.848397891593412	1
GO:0098631	cell adhesion mediator activity	9/2881	76/18639	0.118421052631579	0.766140229087123	0.850170894345082	1
GO:0061891	calcium ion sensor activity	2/2881	21/18639	0.0952380952380952	0.6161551048743	0.857773478151451	1
GO:0070182	DNA polymerase binding	2/2881	21/18639	0.0952380952380952	0.6161551048743	0.857773478151451	1
GO:0005109	frizzled binding	4/2881	38/18639	0.105263157894737	0.681013536966331	0.859639520920829	1
GO:0005501	retinoid binding	4/2881	38/18639	0.105263157894737	0.681013536966331	0.859639520920829	1
GO:0019840	isoprenoid binding	4/2881	38/18639	0.105263157894737	0.681013536966331	0.859639520920829	1
GO:0033612	receptor serine/threonine kinase binding	3/2881	30/18639	0.1	0.646962860118015	0.863720571049751	1
GO:0048019	receptor antagonist activity	3/2881	30/18639	0.1	0.646962860118015	0.863720571049751	1
GO:0016853	isomerase activity	23/2881	180/18639	0.127777777777778	0.826674765706352	0.866323716434273	1
GO:0003995	acyl-CoA dehydrogenase activity	1/2881	12/18639	0.0833333333333333	0.539135716765012	0.866752039272999	1
GO:0004859	phospholipase inhibitor activity	1/2881	12/18639	0.0833333333333333	0.539135716765012	0.866752039272999	1
GO:0005247	voltage-gated chloride channel activity	1/2881	12/18639	0.0833333333333333	0.539135716765012	0.866752039272999	1
GO:0005436	sodium:phosphate symporter activity	1/2881	12/18639	0.0833333333333333	0.539135716765012	0.866752039272999	1
GO:0008179	adenylate cyclase binding	1/2881	12/18639	0.0833333333333333	0.539135716765012	0.866752039272999	1
GO:0008504	monoamine transmembrane transporter activity	1/2881	12/18639	0.0833333333333333	0.539135716765012	0.866752039272999	1
GO:0010853	cyclase activator activity	1/2881	12/18639	0.0833333333333333	0.539135716765012	0.866752039272999	1
GO:0016423	tRNA (guanine) methyltransferase activity	1/2881	12/18639	0.0833333333333333	0.539135716765012	0.866752039272999	1
GO:0016840	carbon-nitrogen lyase activity	1/2881	12/18639	0.0833333333333333	0.539135716765012	0.866752039272999	1
GO:0031543	peptidyl-proline dioxygenase activity	1/2881	12/18639	0.0833333333333333	0.539135716765012	0.866752039272999	1
GO:0042301	phosphate ion binding	1/2881	12/18639	0.0833333333333333	0.539135716765012	0.866752039272999	1
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/2881	12/18639	0.0833333333333333	0.539135716765012	0.866752039272999	1
GO:0070008	serine-type exopeptidase activity	1/2881	12/18639	0.0833333333333333	0.539135716765012	0.866752039272999	1
GO:0070679	inositol 1,4,5 trisphosphate binding	1/2881	12/18639	0.0833333333333333	0.539135716765012	0.866752039272999	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	16/2881	130/18639	0.123076923076923	0.79626198168371	0.870238293672827	1
GO:0140359	ABC-type transporter activity	5/2881	47/18639	0.106382978723404	0.688258361827675	0.871674786120659	1
GO:0008374	O-acyltransferase activity	6/2881	55/18639	0.109090909090909	0.705777665583289	0.872288477800025	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/2881	39/18639	0.102564102564103	0.663551651403092	0.873139357459015	1
GO:0050660	flavin adenine dinucleotide binding	10/2881	86/18639	0.116279069767442	0.752282395486063	0.874359410835521	1
GO:0016881	acid-amino acid ligase activity	2/2881	22/18639	0.0909090909090909	0.588148054652741	0.87523272129345	1
GO:0033691	sialic acid binding	2/2881	22/18639	0.0909090909090909	0.588148054652741	0.87523272129345	1
GO:0140784	metal ion sensor activity	2/2881	22/18639	0.0909090909090909	0.588148054652741	0.87523272129345	1
GO:0016411	acylglycerol O-acyltransferase activity	3/2881	31/18639	0.0967741935483871	0.626093090436788	0.878309157689796	1
GO:0038187	pattern recognition receptor activity	5/2881	48/18639	0.104166666666667	0.673919645956265	0.88318743942634	1
GO:0071949	FAD binding	4/2881	40/18639	0.1	0.646962860118015	0.885502050508157	1
GO:0015085	calcium ion transmembrane transporter activity	18/2881	147/18639	0.122448979591837	0.792199420552671	0.88682742947264	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/2881	13/18639	0.0769230769230769	0.497663738552319	0.88736122888241	1
GO:0004465	lipoprotein lipase activity	1/2881	13/18639	0.0769230769230769	0.497663738552319	0.88736122888241	1
GO:0005172	vascular endothelial growth factor receptor binding	1/2881	13/18639	0.0769230769230769	0.497663738552319	0.88736122888241	1
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/2881	13/18639	0.0769230769230769	0.497663738552319	0.88736122888241	1
GO:0008417	fucosyltransferase activity	1/2881	13/18639	0.0769230769230769	0.497663738552319	0.88736122888241	1
GO:0009982	pseudouridine synthase activity	1/2881	13/18639	0.0769230769230769	0.497663738552319	0.88736122888241	1
GO:0035325	Toll-like receptor binding	1/2881	13/18639	0.0769230769230769	0.497663738552319	0.88736122888241	1
GO:0051011	microtubule minus-end binding	1/2881	13/18639	0.0769230769230769	0.497663738552319	0.88736122888241	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/2881	13/18639	0.0769230769230769	0.497663738552319	0.88736122888241	1
GO:0071837	HMG box domain binding	1/2881	13/18639	0.0769230769230769	0.497663738552319	0.88736122888241	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/2881	13/18639	0.0769230769230769	0.497663738552319	0.88736122888241	1
GO:0089720	caspase binding	1/2881	13/18639	0.0769230769230769	0.497663738552319	0.88736122888241	1
GO:0097157	pre-mRNA intronic binding	1/2881	13/18639	0.0769230769230769	0.497663738552319	0.88736122888241	1
GO:0008378	galactosyltransferase activity	3/2881	32/18639	0.09375	0.606527681360639	0.891491905383197	1
GO:0004896	cytokine receptor activity	11/2881	96/18639	0.114583333333333	0.741311610551892	0.894178013787618	1
GO:0001217	DNA-binding transcription repressor activity	36/2881	278/18639	0.129496402877698	0.837793631807501	0.896298582830579	1
GO:0042923	neuropeptide binding	3/2881	33/18639	0.0909090909090909	0.588148054652741	0.903378553832749	1
GO:0048020	CCR chemokine receptor binding	5/2881	50/18639	0.1	0.646962860118015	0.903575418545476	1
GO:0004806	triacylglycerol lipase activity	2/2881	24/18639	0.0833333333333333	0.539135716765012	0.904359818788375	1
GO:0005540	hyaluronic acid binding	2/2881	24/18639	0.0833333333333333	0.539135716765012	0.904359818788375	1
GO:0015149	hexose transmembrane transporter activity	2/2881	24/18639	0.0833333333333333	0.539135716765012	0.904359818788375	1
GO:0015295	solute:proton symporter activity	2/2881	24/18639	0.0833333333333333	0.539135716765012	0.904359818788375	1
GO:0055056	D-glucose transmembrane transporter activity	2/2881	24/18639	0.0833333333333333	0.539135716765012	0.904359818788375	1
GO:0005344	oxygen carrier activity	1/2881	14/18639	0.0714285714285714	0.462116328655725	0.904783772616425	1
GO:0008494	translation activator activity	1/2881	14/18639	0.0714285714285714	0.462116328655725	0.904783772616425	1
GO:0015926	glucosidase activity	1/2881	14/18639	0.0714285714285714	0.462116328655725	0.904783772616425	1
GO:0019763	immunoglobulin receptor activity	1/2881	14/18639	0.0714285714285714	0.462116328655725	0.904783772616425	1
GO:0030983	mismatched DNA binding	1/2881	14/18639	0.0714285714285714	0.462116328655725	0.904783772616425	1
GO:0031404	chloride ion binding	1/2881	14/18639	0.0714285714285714	0.462116328655725	0.904783772616425	1
GO:0042813	Wnt receptor activity	1/2881	14/18639	0.0714285714285714	0.462116328655725	0.904783772616425	1
GO:0030246	carbohydrate binding	36/2881	280/18639	0.128571428571429	0.831809391580304	0.904949964173444	1
GO:0036002	pre-mRNA binding	6/2881	59/18639	0.101694915254237	0.657928332323405	0.910682053390562	1
GO:0016830	carbon-carbon lyase activity	5/2881	51/18639	0.0980392156862745	0.634277313841191	0.912553464061907	1
GO:1901681	sulfur compound binding	35/2881	275/18639	0.127272727272727	0.823407276513837	0.913550928805134	1
GO:0008175	tRNA methyltransferase activity	3/2881	34/18639	0.0882352941176471	0.570849582457072	0.914074818695072	1
GO:0015020	glucuronosyltransferase activity	3/2881	34/18639	0.0882352941176471	0.570849582457072	0.914074818695072	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	34/2881	268/18639	0.126865671641791	0.82077377776166	0.914133103839557	1
GO:0000030	mannosyltransferase activity	2/2881	25/18639	0.08	0.517570288094412	0.916413621618242	1
GO:0015645	fatty acid ligase activity	2/2881	25/18639	0.08	0.517570288094412	0.916413621618242	1
GO:0120515	fatty acid-CoA ligase activity	2/2881	25/18639	0.08	0.517570288094412	0.916413621618242	1
GO:0004467	long-chain fatty acid-CoA ligase activity	1/2881	15/18639	0.0666666666666667	0.43130857341201	0.919512253211973	1
GO:0004953	icosanoid receptor activity	1/2881	15/18639	0.0666666666666667	0.43130857341201	0.919512253211973	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/2881	15/18639	0.0666666666666667	0.43130857341201	0.919512253211973	1
GO:0008242	omega peptidase activity	1/2881	15/18639	0.0666666666666667	0.43130857341201	0.919512253211973	1
GO:0015116	sulfate transmembrane transporter activity	1/2881	15/18639	0.0666666666666667	0.43130857341201	0.919512253211973	1
GO:0030553	cGMP binding	1/2881	15/18639	0.0666666666666667	0.43130857341201	0.919512253211973	1
GO:0034483	heparan sulfate sulfotransferase activity	1/2881	15/18639	0.0666666666666667	0.43130857341201	0.919512253211973	1
GO:0047372	monoacylglycerol lipase activity	1/2881	15/18639	0.0666666666666667	0.43130857341201	0.919512253211973	1
GO:0048531	beta-1,3-galactosyltransferase activity	1/2881	15/18639	0.0666666666666667	0.43130857341201	0.919512253211973	1
GO:0051371	muscle alpha-actinin binding	1/2881	15/18639	0.0666666666666667	0.43130857341201	0.919512253211973	1
GO:0005262	calcium channel activity	15/2881	131/18639	0.114503816793893	0.740797168074062	0.923059640002266	1
GO:0004435	phosphatidylinositol phospholipase C activity	2/2881	26/18639	0.0769230769230769	0.497663738552319	0.927027641281307	1
GO:0005227	calcium-activated cation channel activity	2/2881	26/18639	0.0769230769230769	0.497663738552319	0.927027641281307	1
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	2/2881	26/18639	0.0769230769230769	0.497663738552319	0.927027641281307	1
GO:0019865	immunoglobulin binding	2/2881	26/18639	0.0769230769230769	0.497663738552319	0.927027641281307	1
GO:0140097	catalytic activity, acting on DNA	43/2881	336/18639	0.12797619047619	0.82795842217484	0.927467104412413	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	15/2881	132/18639	0.113636363636364	0.735185068315926	0.927984047054714	1
GO:0017046	peptide hormone binding	5/2881	53/18639	0.0943396226415094	0.610342320866051	0.928328925176318	1
GO:1901505	carbohydrate derivative transmembrane transporter activity	5/2881	53/18639	0.0943396226415094	0.610342320866051	0.928328925176318	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	7/2881	70/18639	0.1	0.646962860118015	0.931008011941349	1
GO:0016782	transferase activity, transferring sulphur-containing groups	7/2881	70/18639	0.1	0.646962860118015	0.931008011941349	1
GO:0005149	interleukin-1 receptor binding	1/2881	16/18639	0.0625	0.404351787573759	0.931963133715426	1
GO:0005159	insulin-like growth factor receptor binding	1/2881	16/18639	0.0625	0.404351787573759	0.931963133715426	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/2881	16/18639	0.0625	0.404351787573759	0.931963133715426	1
GO:0008296	3'-5'-DNA exonuclease activity	1/2881	16/18639	0.0625	0.404351787573759	0.931963133715426	1
GO:0015378	sodium:chloride symporter activity	1/2881	16/18639	0.0625	0.404351787573759	0.931963133715426	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/2881	16/18639	0.0625	0.404351787573759	0.931963133715426	1
GO:0016722	oxidoreductase activity, acting on metal ions	1/2881	16/18639	0.0625	0.404351787573759	0.931963133715426	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/2881	16/18639	0.0625	0.404351787573759	0.931963133715426	1
GO:0055102	lipase inhibitor activity	1/2881	16/18639	0.0625	0.404351787573759	0.931963133715426	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/2881	16/18639	0.0625	0.404351787573759	0.931963133715426	1
GO:0015370	solute:sodium symporter activity	8/2881	79/18639	0.10126582278481	0.655152263410648	0.936115730016598	1
GO:0008509	monoatomic anion transmembrane transporter activity	17/2881	149/18639	0.114093959731544	0.738145545101091	0.936183923713582	1
GO:0035255	ionotropic glutamate receptor binding	2/2881	27/18639	0.0740740740740741	0.479231748235566	0.936358809002459	1
GO:0005253	monoatomic anion channel activity	11/2881	103/18639	0.106796116504854	0.690931209834773	0.936781095687293	1
GO:0140299	molecular sensor activity	7/2881	71/18639	0.0985915492957746	0.637850707158606	0.936946741558799	1
GO:0004180	carboxypeptidase activity	4/2881	46/18639	0.0869565217391304	0.562576400102621	0.939741106394785	1
GO:0022829	wide pore channel activity	3/2881	37/18639	0.0810810810810811	0.524564481176769	0.940002950208692	1
GO:0030280	structural constituent of skin epidermis	3/2881	37/18639	0.0810810810810811	0.524564481176769	0.940002950208692	1
GO:0042805	actinin binding	3/2881	37/18639	0.0810810810810811	0.524564481176769	0.940002950208692	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/2881	17/18639	0.0588235294117647	0.380566388304715	0.942488516938637	1
GO:0009881	photoreceptor activity	1/2881	17/18639	0.0588235294117647	0.380566388304715	0.942488516938637	1
GO:0019198	transmembrane receptor protein phosphatase activity	1/2881	17/18639	0.0588235294117647	0.380566388304715	0.942488516938637	1
GO:0016866	intramolecular transferase activity	2/2881	28/18639	0.0714285714285714	0.462116328655725	0.944549959598922	1
GO:0045499	chemorepellent activity	2/2881	28/18639	0.0714285714285714	0.462116328655725	0.944549959598922	1
GO:0051393	alpha-actinin binding	2/2881	28/18639	0.0714285714285714	0.462116328655725	0.944549959598922	1
GO:0030170	pyridoxal phosphate binding	5/2881	56/18639	0.0892857142857143	0.577645410819656	0.94725323386644	1
GO:0017171	serine hydrolase activity	23/2881	198/18639	0.116161616161616	0.751522514278502	0.949803589195409	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	13/2881	122/18639	0.10655737704918	0.689386654224114	0.950767936032442	1
GO:0015291	secondary active transmembrane transporter activity	35/2881	287/18639	0.121951219512195	0.788979097704896	0.951252177499858	1
GO:0015373	monoatomic anion:sodium symporter activity	1/2881	18/18639	0.0555555555555556	0.359423811176675	0.951386088773015	1
GO:0016854	racemase and epimerase activity	1/2881	18/18639	0.0555555555555556	0.359423811176675	0.951386088773015	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/2881	18/18639	0.0555555555555556	0.359423811176675	0.951386088773015	1
GO:0034185	apolipoprotein binding	1/2881	18/18639	0.0555555555555556	0.359423811176675	0.951386088773015	1
GO:0004252	serine-type endopeptidase activity	20/2881	176/18639	0.113636363636364	0.735185068315926	0.951481574867153	1
GO:0004181	metallocarboxypeptidase activity	2/2881	29/18639	0.0689655172413793	0.44618128284001	0.9517304384339	1
GO:0035250	UDP-galactosyltransferase activity	2/2881	29/18639	0.0689655172413793	0.44618128284001	0.9517304384339	1
GO:0099604	ligand-gated calcium channel activity	2/2881	29/18639	0.0689655172413793	0.44618128284001	0.9517304384339	1
GO:0048029	monosaccharide binding	7/2881	74/18639	0.0945945945945946	0.61199189470623	0.95214056747836	1
GO:0070279	vitamin B6 binding	5/2881	57/18639	0.087719298245614	0.567511280805276	0.952475098922397	1
GO:0015293	symporter activity	16/2881	146/18639	0.10958904109589	0.709000394649879	0.953152743763555	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/2881	30/18639	0.0666666666666667	0.43130857341201	0.958016857532768	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/2881	30/18639	0.0666666666666667	0.43130857341201	0.958016857532768	1
GO:0022839	monoatomic ion-gated channel activity	2/2881	30/18639	0.0666666666666667	0.43130857341201	0.958016857532768	1
GO:0004177	aminopeptidase activity	3/2881	40/18639	0.075	0.485222145088511	0.95851306045073	1
GO:0015144	carbohydrate transmembrane transporter activity	3/2881	40/18639	0.075	0.485222145088511	0.95851306045073	1
GO:0008381	mechanosensitive monoatomic ion channel activity	1/2881	19/18639	0.0526315789473684	0.340506768483166	0.958907525765923	1
GO:0008574	plus-end-directed microtubule motor activity	1/2881	19/18639	0.0526315789473684	0.340506768483166	0.958907525765923	1
GO:0015245	fatty acid transmembrane transporter activity	1/2881	19/18639	0.0526315789473684	0.340506768483166	0.958907525765923	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/2881	19/18639	0.0526315789473684	0.340506768483166	0.958907525765923	1
GO:0030506	ankyrin binding	1/2881	19/18639	0.0526315789473684	0.340506768483166	0.958907525765923	1
GO:0042577	lipid phosphatase activity	1/2881	19/18639	0.0526315789473684	0.340506768483166	0.958907525765923	1
GO:0008236	serine-type peptidase activity	22/2881	194/18639	0.11340206185567	0.733669222814243	0.959445884967088	1
GO:0140375	immune receptor activity	17/2881	156/18639	0.108974358974359	0.705023629615785	0.95996012813544	1
GO:0015103	inorganic anion transmembrane transporter activity	18/2881	165/18639	0.109090909090909	0.705777665583289	0.963311373220769	1
GO:0017147	Wnt-protein binding	2/2881	31/18639	0.0645161290322581	0.417395393624526	0.963513940280559	1
GO:0015171	amino acid transmembrane transporter activity	10/2881	102/18639	0.0980392156862745	0.634277313841191	0.964045714232376	1
GO:0042562	hormone binding	9/2881	94/18639	0.0957446808510638	0.619432525644908	0.964718389738072	1
GO:0010851	cyclase regulator activity	1/2881	20/18639	0.05	0.323481430059007	0.965265604083237	1
GO:0140664	ATP-dependent DNA damage sensor activity	1/2881	20/18639	0.05	0.323481430059007	0.965265604083237	1
GO:0019199	transmembrane receptor protein kinase activity	7/2881	78/18639	0.0897435897435897	0.580607694977705	0.967274681499482	1
GO:0004867	serine-type endopeptidase inhibitor activity	9/2881	95/18639	0.0947368421052632	0.612912183269698	0.96770552124309	1
GO:0071813	lipoprotein particle binding	2/2881	32/18639	0.0625	0.404351787573759	0.968315409273716	1
GO:0071814	protein-lipid complex binding	2/2881	32/18639	0.0625	0.404351787573759	0.968315409273716	1
GO:0001846	opsonin binding	1/2881	21/18639	0.0476190476190476	0.30807755243715	0.970640210379826	1
GO:0015125	bile acid transmembrane transporter activity	1/2881	21/18639	0.0476190476190476	0.30807755243715	0.970640210379826	1
GO:0005245	voltage-gated calcium channel activity	3/2881	43/18639	0.0697674418604651	0.451369437291638	0.971556828612195	1
GO:0008514	organic anion transmembrane transporter activity	31/2881	269/18639	0.115241635687732	0.745570582292136	0.973725044323472	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	3/2881	44/18639	0.0681818181818182	0.441111040989555	0.974962916132659	1
GO:0015377	chloride:monoatomic cation symporter activity	1/2881	22/18639	0.0454545454545455	0.29407402732637	0.975183424145844	1
GO:0090482	vitamin transmembrane transporter activity	2/2881	34/18639	0.0588235294117647	0.380566388304715	0.976156762888496	1
GO:0015294	solute:monoatomic cation symporter activity	11/2881	116/18639	0.0948275862068965	0.613499263905014	0.978031317384834	1
GO:0046943	carboxylic acid transmembrane transporter activity	20/2881	188/18639	0.106382978723404	0.688258361827675	0.97803707655989	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/2881	23/18639	0.0434782608695652	0.281288200051311	0.979023814919643	1
GO:0005283	amino acid:sodium symporter activity	1/2881	23/18639	0.0434782608695652	0.281288200051311	0.979023814919643	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	19/2881	181/18639	0.104972375690608	0.679132284101783	0.979263591311614	1
GO:0005343	organic acid:sodium symporter activity	2/2881	35/18639	0.0571428571428571	0.36969306292458	0.979337076601447	1
GO:0005342	organic acid transmembrane transporter activity	20/2881	189/18639	0.105820105820106	0.684616783193666	0.979509139524071	1
GO:0005254	chloride channel activity	7/2881	83/18639	0.0843373493975904	0.545631327810374	0.980023699514639	1
GO:0001664	G protein-coupled receptor binding	34/2881	297/18639	0.114478114478114	0.740630883636784	0.980833523344651	1
GO:0170055	lipid transmembrane transporter activity	4/2881	56/18639	0.0714285714285714	0.462116328655725	0.980982089735351	1
GO:0004033	aldo-keto reductase (NADPH) activity	2/2881	36/18639	0.0555555555555556	0.359423811176675	0.982104294846361	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/2881	24/18639	0.0416666666666667	0.269567858382506	0.982270075621003	1
GO:0030215	semaphorin receptor binding	1/2881	24/18639	0.0416666666666667	0.269567858382506	0.982270075621003	1
GO:0004519	endonuclease activity	12/2881	127/18639	0.094488188976378	0.611303489875289	0.98259107926171	1
GO:0008238	exopeptidase activity	9/2881	102/18639	0.0882352941176471	0.570849582457072	0.982967908273852	1
GO:0046906	tetrapyrrole binding	15/2881	152/18639	0.0986842105263158	0.638450190905935	0.983238344563828	1
GO:0008237	metallopeptidase activity	19/2881	184/18639	0.103260869565217	0.668059475121863	0.983273764486069	1
GO:0001848	complement binding	1/2881	25/18639	0.04	0.258785144047206	0.985014094537784	1
GO:0005251	delayed rectifier potassium channel activity	1/2881	25/18639	0.04	0.258785144047206	0.985014094537784	1
GO:0015271	outward rectifier potassium channel activity	1/2881	25/18639	0.04	0.258785144047206	0.985014094537784	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/2881	25/18639	0.04	0.258785144047206	0.985014094537784	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/2881	25/18639	0.04	0.258785144047206	0.985014094537784	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/2881	25/18639	0.04	0.258785144047206	0.985014094537784	1
GO:0008188	neuropeptide receptor activity	3/2881	48/18639	0.0625	0.404351787573759	0.985084937770443	1
GO:0003777	microtubule motor activity	5/2881	68/18639	0.0735294117647059	0.475707985380893	0.985767490559024	1
GO:0015108	chloride transmembrane transporter activity	11/2881	121/18639	0.0909090909090909	0.588148054652741	0.98581268705051	1
GO:0031406	carboxylic acid binding	19/2881	187/18639	0.101604278074866	0.657341943435416	0.986568186154627	1
GO:0005539	glycosaminoglycan binding	26/2881	242/18639	0.107438016528926	0.695084064589602	0.986659275369278	1
GO:0005004	GPI-linked ephrin receptor activity	3/2881	49/18639	0.0612244897959184	0.396099710276335	0.986920215227797	1
GO:0005008	hepatocyte growth factor receptor activity	3/2881	49/18639	0.0612244897959184	0.396099710276335	0.986920215227797	1
GO:0005009	insulin receptor activity	3/2881	49/18639	0.0612244897959184	0.396099710276335	0.986920215227797	1
GO:0005011	macrophage colony-stimulating factor receptor activity	3/2881	49/18639	0.0612244897959184	0.396099710276335	0.986920215227797	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	3/2881	49/18639	0.0612244897959184	0.396099710276335	0.986920215227797	1
GO:0005020	stem cell factor receptor activity	3/2881	49/18639	0.0612244897959184	0.396099710276335	0.986920215227797	1
GO:0008288	boss receptor activity	3/2881	49/18639	0.0612244897959184	0.396099710276335	0.986920215227797	1
GO:0036332	placental growth factor receptor activity	3/2881	49/18639	0.0612244897959184	0.396099710276335	0.986920215227797	1
GO:0038062	protein tyrosine kinase collagen receptor activity	3/2881	49/18639	0.0612244897959184	0.396099710276335	0.986920215227797	1
GO:0060175	brain-derived neurotrophic factor receptor activity	3/2881	49/18639	0.0612244897959184	0.396099710276335	0.986920215227797	1
GO:0004529	DNA exonuclease activity	1/2881	26/18639	0.0384615384615385	0.248831869276159	0.987333552668044	1
GO:0030247	polysaccharide binding	1/2881	26/18639	0.0384615384615385	0.248831869276159	0.987333552668044	1
GO:0008201	heparin binding	17/2881	172/18639	0.0988372093023256	0.639440036163154	0.98757695909715	1
GO:0043177	organic acid binding	19/2881	189/18639	0.100529100529101	0.650385944033983	0.98842345288924	1
GO:0005006	epidermal growth factor receptor activity	3/2881	50/18639	0.06	0.388177716070809	0.988537371661806	1
GO:0005007	fibroblast growth factor receptor activity	3/2881	50/18639	0.06	0.388177716070809	0.988537371661806	1
GO:0005017	platelet-derived growth factor receptor activity	3/2881	50/18639	0.06	0.388177716070809	0.988537371661806	1
GO:0005019	platelet-derived growth factor beta-receptor activity	3/2881	50/18639	0.06	0.388177716070809	0.988537371661806	1
GO:0005104	fibroblast growth factor receptor binding	1/2881	27/18639	0.037037037037037	0.239615874117783	0.989294119732104	1
GO:0008395	steroid hydroxylase activity	1/2881	27/18639	0.037037037037037	0.239615874117783	0.989294119732104	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/2881	27/18639	0.037037037037037	0.239615874117783	0.989294119732104	1
GO:0023026	MHC class II protein complex binding	1/2881	27/18639	0.037037037037037	0.239615874117783	0.989294119732104	1
GO:0005010	insulin-like growth factor receptor activity	3/2881	51/18639	0.0588235294117647	0.380566388304715	0.989961104824716	1
GO:0005021	vascular endothelial growth factor receptor activity	3/2881	51/18639	0.0588235294117647	0.380566388304715	0.989961104824716	1
GO:0005030	neurotrophin receptor activity	3/2881	51/18639	0.0588235294117647	0.380566388304715	0.989961104824716	1
GO:0140662	ATP-dependent protein folding chaperone	2/2881	40/18639	0.05	0.323481430059007	0.989987971895874	1
GO:0005201	extracellular matrix structural constituent	16/2881	168/18639	0.0952380952380952	0.6161551048743	0.991053149482322	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	3/2881	52/18639	0.0576923076923077	0.373247803914239	0.991213513935987	1
GO:0004620	phospholipase activity	9/2881	109/18639	0.0825688073394495	0.534189517528636	0.991309669117358	1
GO:0005003	ephrin receptor activity	3/2881	53/18639	0.0566037735849057	0.366205392519631	0.992314340240292	1
GO:0005005	transmembrane-ephrin receptor activity	3/2881	53/18639	0.0566037735849057	0.366205392519631	0.992314340240292	1
GO:0008146	sulfotransferase activity	3/2881	53/18639	0.0566037735849057	0.366205392519631	0.992314340240292	1
GO:0038064	collagen receptor activity	3/2881	53/18639	0.0566037735849057	0.366205392519631	0.992314340240292	1
GO:0005416	amino acid:monoatomic cation symporter activity	1/2881	29/18639	0.0344827586206897	0.223090641420005	0.992352056291514	1
GO:0005506	iron ion binding	14/2881	154/18639	0.0909090909090909	0.588148054652741	0.992805569847172	1
GO:0016500	protein-hormone receptor activity	4/2881	67/18639	0.0597014925373134	0.386246483652546	0.995113104902632	1
GO:0020037	heme binding	12/2881	142/18639	0.0845070422535211	0.546729177564519	0.995439166793307	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/2881	46/18639	0.0434782608695652	0.281288200051311	0.995870505265806	1
GO:0099095	ligand-gated monoatomic anion channel activity	2/2881	47/18639	0.0425531914893617	0.27530334473107	0.996442350555874	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/2881	34/18639	0.0294117647058824	0.190283194152357	0.996701810329275	1
GO:0016831	carboxy-lyase activity	1/2881	34/18639	0.0294117647058824	0.190283194152357	0.996701810329275	1
GO:0019825	oxygen binding	1/2881	34/18639	0.0294117647058824	0.190283194152357	0.996701810329275	1
GO:0004222	metalloendopeptidase activity	8/2881	110/18639	0.0727272727272727	0.470518443722192	0.99692210424807	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	3/2881	60/18639	0.05	0.323481430059007	0.997034895043327	1
GO:0016298	lipase activity	10/2881	130/18639	0.0769230769230769	0.497663738552319	0.997395873081383	1
GO:0008528	G protein-coupled peptide receptor activity	9/2881	122/18639	0.0737704918032787	0.477267683693617	0.99769186982141	1
GO:0001653	peptide receptor activity	9/2881	128/18639	0.0703125	0.454895761020479	0.998784352061309	1
GO:0071855	neuropeptide receptor binding	1/2881	40/18639	0.025	0.161740715029504	0.998798256937143	1
GO:0004520	DNA endonuclease activity	1/2881	42/18639	0.0238095238095238	0.154038776218575	0.999141732388928	1
GO:0008083	growth factor activity	12/2881	162/18639	0.0740740740740741	0.479231748235566	0.999357798689734	1
GO:0001216	DNA-binding transcription activator activity	52/2881	491/18639	0.105906313645621	0.685174515807266	0.999372301125591	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	51/2881	484/18639	0.105371900826446	0.681717063347495	0.999401747465563	1
GO:0005125	cytokine activity	20/2881	234/18639	0.0854700854700855	0.552959709502577	0.999426061395498	1
GO:0042605	peptide antigen binding	1/2881	45/18639	0.0222222222222222	0.14376952447067	0.999482026827707	1
GO:0004497	monooxygenase activity	6/2881	106/18639	0.0566037735849057	0.366205392519631	0.999498755179471	1
GO:0004536	DNA nuclease activity	2/2881	64/18639	0.03125	0.20217589378688	0.999730936979532	1
GO:0038024	cargo receptor activity	2/2881	65/18639	0.0307692307692308	0.199065495420928	0.999769381938587	1
GO:0015081	sodium ion transmembrane transporter activity	11/2881	164/18639	0.0670731707317073	0.433938503737693	0.999807565920873	1
GO:0005261	monoatomic cation channel activity	28/2881	341/18639	0.0821114369501466	0.531230500976669	0.999980104241797	1
GO:0005179	hormone activity	6/2881	132/18639	0.0454545454545455	0.29407402732637	0.999982127266685	1
GO:0003730	mRNA 3'-UTR binding	19/2881	262/18639	0.0725190839694656	0.46917153978024	0.999982567315506	1
GO:0046873	metal ion transmembrane transporter activity	39/2881	450/18639	0.0866666666666667	0.560701145435613	0.999994402195951	1
GO:0005216	monoatomic ion channel activity	38/2881	448/18639	0.0848214285714286	0.548763140278673	0.99999678315023	1
GO:0005244	voltage-gated monoatomic ion channel activity	8/2881	173/18639	0.046242774566474	0.299173576933186	0.99999840713909	1
GO:0005249	voltage-gated potassium channel activity	2/2881	98/18639	0.0204081632653061	0.132033236758778	0.999998703530771	1
GO:0022832	voltage-gated channel activity	8/2881	175/18639	0.0457142857142857	0.295754450339664	0.999998771392491	1
GO:0022843	voltage-gated monoatomic cation channel activity	5/2881	143/18639	0.034965034965035	0.226210790251054	0.999999234193223	1
GO:0099094	ligand-gated monoatomic cation channel activity	4/2881	136/18639	0.0294117647058824	0.190283194152357	0.999999678853739	1
GO:0030594	neurotransmitter receptor activity	1/2881	97/18639	0.0103092783505155	0.0666972020740221	0.9999999193315	1
GO:0015079	potassium ion transmembrane transporter activity	5/2881	160/18639	0.03125	0.20217589378688	0.999999933232968	1
GO:0005267	potassium channel activity	2/2881	124/18639	0.0161290322580645	0.104348848406131	0.999999979929475	1
GO:0003823	antigen binding	4/2881	174/18639	0.0229885057471264	0.148727094280003	0.999999998941605	1
GO:0015276	ligand-gated monoatomic ion channel activity	4/2881	186/18639	0.021505376344086	0.139131797874842	0.999999999831763	1
GO:0022834	ligand-gated channel activity	4/2881	188/18639	0.0212765957446809	0.137651672365535	0.999999999876342	1
GO:0022836	gated channel activity	12/2881	318/18639	0.0377358490566038	0.244136928346421	0.999999999996813	1
GO:0045182	translation regulator activity	11/2881	356/18639	0.0308988764044944	0.199904254530847	0.999999999999997	1
GO:0030371	translation repressor activity	6/2881	329/18639	0.0182370820668693	0.117987147741887	1	1