ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005520 insulin-like growth factor binding 7/282 19/18639 0.368421052631579 24.3510638297872 7.26652707160509e-09 4.83224050261739e-06 GO:0031994 insulin-like growth factor I binding 6/282 13/18639 0.461538461538462 30.505728314239 1.78547841475269e-08 5.93671572905271e-06 GO:0031386 protein tag activity 5/282 15/18639 0.333333333333333 22.031914893617 2.02945625959777e-06 0.00033739710315813 GO:0141047 molecular tag activity 5/282 15/18639 0.333333333333333 22.031914893617 2.02945625959777e-06 0.00033739710315813 GO:0048306 calcium-dependent protein binding 9/282 80/18639 0.1125 7.43577127659575 3.31550984971373e-06 0.000440962810011926 GO:0050786 RAGE receptor binding 4/282 11/18639 0.363636363636364 24.0348162475822 1.55679639825541e-05 0.00172544934139975 GO:0003925 G protein activity 6/282 54/18639 0.111111111111111 7.34397163120567 0.000159672483366973 0.0151688859198624 GO:0005085 guanyl-nucleotide exchange factor activity 12/282 230/18639 0.0521739130434783 3.44847363552266 0.000209294003633965 0.0173975640520733 GO:0030695 GTPase regulator activity 18/282 489/18639 0.0368098159509202 2.43297219684114 0.000496250744852801 0.0312389177508103 GO:0060589 nucleoside-triphosphatase regulator activity 18/282 490/18639 0.036734693877551 2.42800694745984 0.000508269494328037 0.0312389177508103 GO:0019864 IgG binding 3/282 11/18639 0.272727272727273 18.0261121856867 0.000516733977832953 0.0312389177508103 GO:0005504 fatty acid binding 5/282 47/18639 0.106382978723404 7.03146220009054 0.000697991828544302 0.0386803804984967 GO:0035325 Toll-like receptor binding 3/282 13/18639 0.230769230769231 15.2528641571195 0.000875793516020588 0.0448002067810532 GO:0019838 growth factor binding 8/282 136/18639 0.0588235294117647 3.88798498122653 0.00110220064774787 0.048865144414063 GO:0019763 immunoglobulin receptor activity 3/282 14/18639 0.214285714285714 14.1633738601824 0.00110222130257285 0.048865144414063 GO:0003735 structural constituent of ribosome 9/282 175/18639 0.0514285714285714 3.39920972644377 0.00141647525677605 0.0588722528597547 GO:0016209 antioxidant activity 6/282 86/18639 0.0697674418604651 4.61133102424542 0.00194354011417699 0.0735601196986486 GO:0036041 long-chain fatty acid binding 3/282 17/18639 0.176470588235294 11.6639549436796 0.00199110098432432 0.0735601196986486 GO:0005501 retinoid binding 4/282 38/18639 0.105263157894737 6.95744680851064 0.00252592701293628 0.0839870731801313 GO:0019840 isoprenoid binding 4/282 38/18639 0.105263157894737 6.95744680851064 0.00252592701293628 0.0839870731801313 GO:0016918 retinal binding 3/282 19/18639 0.157894736842105 10.436170212766 0.0027746255348481 0.0878631419368564 GO:0051020 GTPase binding 12/282 315/18639 0.0380952380952381 2.51793313069909 0.00319402147516691 0.0926132236339798 GO:0003779 actin binding 15/282 443/18639 0.0338600451467269 2.23800489890015 0.00320316412568652 0.0926132236339798 GO:0048487 beta-tubulin binding 4/282 42/18639 0.0952380952380952 6.29483282674772 0.0036536393729102 0.100708531555931 GO:0031267 small GTPase binding 11/282 283/18639 0.03886925795053 2.56909254943237 0.00402498720864906 0.100708531555931 GO:0005201 extracellular matrix structural constituent 8/282 168/18639 0.0476190476190476 3.14741641337386 0.00412190494351221 0.100708531555931 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/282 22/18639 0.136363636363636 9.01305609284333 0.00426455038915492 0.100708531555931 GO:0031683 G-protein beta/gamma-subunit complex binding 3/282 22/18639 0.136363636363636 9.01305609284333 0.00426455038915492 0.100708531555931 GO:0051015 actin filament binding 9/282 209/18639 0.0430622009569378 2.84622823984526 0.00465993203390249 0.100708531555931 GO:0042379 chemokine receptor binding 5/282 72/18639 0.0694444444444444 4.58998226950355 0.00468888529990019 0.100708531555931 GO:0008009 chemokine activity 4/282 45/18639 0.0888888888888889 5.87517730496454 0.00469468342591559 0.100708531555931 GO:0045296 cadherin binding 12/282 334/18639 0.0359281437125748 2.37469741368327 0.00507995698669438 0.105567856129743 GO:0031625 ubiquitin protein ligase binding 11/282 302/18639 0.0364238410596026 2.4074608989714 0.00649081347783798 0.130799726144311 GO:0019865 immunoglobulin binding 3/282 26/18639 0.115384615384615 7.62643207855974 0.00688663454732065 0.131794640794175 GO:0033293 monocarboxylic acid binding 5/282 79/18639 0.0632911392405063 4.1832749798007 0.0069365600417987 0.131794640794175 GO:0005543 phospholipid binding 15/282 497/18639 0.0301810865191147 1.99484138875808 0.00898277984513302 0.165931905472596 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/282 10/18639 0.2 13.2191489361702 0.00947377474550273 0.170271897452954 GO:0044389 ubiquitin-like protein ligase binding 11/282 322/18639 0.0341614906832298 2.25792916611603 0.0102308407821164 0.175411417074412 GO:0001968 fibronectin binding 3/282 30/18639 0.1 6.60957446808511 0.0102872861141384 0.175411417074412 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/282 11/18639 0.181818181818182 12.0174081237911 0.0114642282494293 0.18273247740058 GO:0047676 arachidonate-CoA ligase activity 2/282 11/18639 0.181818181818182 12.0174081237911 0.0114642282494293 0.18273247740058 GO:0035091 phosphatidylinositol binding 10/282 284/18639 0.0352112676056338 2.32731495355109 0.0115409985726682 0.18273247740058 GO:0016874 ligase activity 7/282 167/18639 0.0419161676646707 2.77048031596382 0.0137537268102144 0.212702984390525 GO:0015631 tubulin binding 12/282 385/18639 0.0311688311688312 2.06012710693562 0.0146743956344273 0.221783479474868 GO:0061631 ubiquitin conjugating enzyme activity 3/282 35/18639 0.0857142857142857 5.66534954407295 0.0156926426213237 0.231902385404006 GO:0023023 MHC protein complex binding 3/282 37/18639 0.0810810810810811 5.35911443358252 0.0182237984480022 0.251366531264357 GO:0044548 S100 protein binding 2/282 14/18639 0.142857142857143 9.44224924012158 0.0184107386862719 0.251366531264357 GO:0046030 inositol trisphosphate phosphatase activity 2/282 14/18639 0.142857142857143 9.44224924012158 0.0184107386862719 0.251366531264357 GO:0050840 extracellular matrix binding 4/282 67/18639 0.0597014925373134 3.946014607812 0.0186710168256882 0.251366531264357 GO:0004467 long-chain fatty acid-CoA ligase activity 2/282 15/18639 0.133333333333333 8.81276595744681 0.0210335554247661 0.251366531264357 GO:0106310 protein serine kinase activity 11/282 361/18639 0.0304709141274238 2.01399776035834 0.022046528267749 0.251366531264357 GO:1901981 phosphatidylinositol phosphate binding 7/282 185/18639 0.0378378378378378 2.50092006900518 0.0227538265232982 0.251366531264357 GO:0005518 collagen binding 4/282 72/18639 0.0555555555555556 3.67198581560284 0.0236474282576281 0.251366531264357 GO:0004708 MAP kinase kinase activity 2/282 16/18639 0.125 8.26196808510638 0.0238014672350419 0.251366531264357 GO:0005521 lamin binding 2/282 16/18639 0.125 8.26196808510638 0.0238014672350419 0.251366531264357 GO:0019841 retinol binding 2/282 16/18639 0.125 8.26196808510638 0.0238014672350419 0.251366531264357 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/282 41/18639 0.0731707317073171 4.83627400103788 0.0239267861434545 0.251366531264357 GO:0016877 ligase activity, forming carbon-sulfur bonds 3/282 41/18639 0.0731707317073171 4.83627400103788 0.0239267861434545 0.251366531264357 GO:0061650 ubiquitin-like protein conjugating enzyme activity 3/282 41/18639 0.0731707317073171 4.83627400103788 0.0239267861434545 0.251366531264357 GO:0000287 magnesium ion binding 8/282 230/18639 0.0347826086956522 2.29898242368178 0.0241602127659681 0.251366531264357 GO:0008017 microtubule binding 9/282 276/18639 0.0326086956521739 2.15529602220166 0.0250742060162869 0.251366531264357 GO:0016805 dipeptidase activity 2/282 17/18639 0.117647058823529 7.77596996245307 0.0267095160684709 0.251366531264357 GO:0030547 signaling receptor inhibitor activity 3/282 44/18639 0.0681818181818182 4.50652804642166 0.0287653188793639 0.251366531264357 GO:0003924 GTPase activity 10/282 331/18639 0.0302114803625378 1.99685029247284 0.0297409622875001 0.251366531264357 GO:0050811 GABA receptor binding 2/282 18/18639 0.111111111111111 7.34397163120567 0.0297528597578801 0.251366531264357 GO:0098641 cadherin binding involved in cell-cell adhesion 2/282 18/18639 0.111111111111111 7.34397163120567 0.0297528597578801 0.251366531264357 GO:1990381 ubiquitin-specific protease binding 2/282 18/18639 0.111111111111111 7.34397163120567 0.0297528597578801 0.251366531264357 GO:0140375 immune receptor activity 6/282 156/18639 0.0384615384615385 2.54214402618658 0.031548100337362 0.251366531264357 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 8/282 243/18639 0.0329218106995885 2.17599159443131 0.0320359561383984 0.251366531264357 GO:0004674 protein serine/threonine kinase activity 12/282 433/18639 0.0277136258660508 1.83175273942312 0.0327063467969072 0.251366531264357 GO:0004676 3-phosphoinositide-dependent protein kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0004711 ribosomal protein S6 kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0035175 histone H3S10 kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0035979 histone H2AXS139 kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0044022 histone H3S28 kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0044023 histone H4S1 kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0044024 histone H2AS1 kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0044025 histone H2BS14 kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0072354 histone H3T3 kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0072371 histone H2AS121 kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0072518 Rho-dependent protein serine/threonine kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0140823 histone H2BS36 kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0140855 histone H3S57 kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0140995 histone H2A kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0140997 histone H4 kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0140998 histone H2B kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:1990244 histone H2AT120 kinase activity 8/282 245/18639 0.0326530612244898 2.15822839774208 0.0333865910007659 0.251366531264357 GO:0022853 active monoatomic ion transmembrane transporter activity 5/282 118/18639 0.0423728813559322 2.80066714749369 0.0336664239505261 0.251366531264357 GO:0004677 DNA-dependent protein kinase activity 8/282 246/18639 0.032520325203252 2.14945511157239 0.0340762433641686 0.251366531264357 GO:0140857 histone H3T45 kinase activity 8/282 246/18639 0.032520325203252 2.14945511157239 0.0340762433641686 0.251366531264357 GO:0035402 histone H3T11 kinase activity 8/282 247/18639 0.0323886639676113 2.14075286415712 0.0347755201147682 0.251366531264357 GO:0035403 histone H3T6 kinase activity 8/282 247/18639 0.0323886639676113 2.14075286415712 0.0347755201147682 0.251366531264357 GO:0004679 AMP-activated protein kinase activity 8/282 248/18639 0.032258064516129 2.13212079615649 0.0354844709161445 0.253733044722969 GO:0052745 inositol phosphate phosphatase activity 2/282 20/18639 0.1 6.60957446808511 0.0362266283809606 0.256284126312115 GO:0001540 amyloid-beta binding 4/282 83/18639 0.0481927710843374 3.18533709305306 0.0371971705404683 0.259469888473025 GO:0001664 G protein-coupled receptor binding 9/282 297/18639 0.0303030303030303 2.00290135396518 0.037457307208136 0.259469888473025 GO:0048020 CCR chemokine receptor binding 3/282 50/18639 0.06 3.96574468085106 0.0398710947273388 0.273343072099797 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/282 86/18639 0.0465116279069767 3.07422068283028 0.0415264895118853 0.281786893116364 GO:0141003 histone H2AX kinase activity 10/282 354/18639 0.0282485875706215 1.86711143166246 0.0437168828129537 0.293653808794083 GO:0140996 histone H3 kinase activity 10/282 357/18639 0.0280112044817927 1.85142141963168 0.0458215028283248 0.299488788360196 GO:0035591 signaling adaptor activity 5/282 129/18639 0.0387596899224806 2.56185056902524 0.0464571654150864 0.299488788360196 GO:0004602 glutathione peroxidase activity 2/282 23/18639 0.0869565217391304 5.74745605920444 0.0468373443450532 0.299488788360196 GO:0005212 structural constituent of eye lens 2/282 23/18639 0.0869565217391304 5.74745605920444 0.0468373443450532 0.299488788360196 GO:0031681 G-protein beta-subunit binding 2/282 23/18639 0.0869565217391304 5.74745605920444 0.0468373443450532 0.299488788360196 GO:0035173 histone kinase activity 10/282 360/18639 0.0277777777777778 1.83599290780142 0.0479937554169081 0.303077683571881 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/282 54/18639 0.0555555555555556 3.67198581560284 0.0483101270054426 0.303077683571881 GO:0140313 molecular sequestering activity 3/282 55/18639 0.0545454545454545 3.60522243713733 0.0505459270704864 0.314140574783864 GO:0004857 enzyme inhibitor activity 11/282 416/18639 0.0264423076923077 1.74772401800327 0.0525287868472415 0.321082528330567 GO:0015645 fatty acid ligase activity 2/282 25/18639 0.08 5.28765957446809 0.0544610485834775 0.321082528330567 GO:0015662 P-type ion transporter activity 2/282 25/18639 0.08 5.28765957446809 0.0544610485834775 0.321082528330567 GO:0120515 fatty acid-CoA ligase activity 2/282 25/18639 0.08 5.28765957446809 0.0544610485834775 0.321082528330567 GO:0140358 P-type transmembrane transporter activity 2/282 25/18639 0.08 5.28765957446809 0.0544610485834775 0.321082528330567 GO:0005096 GTPase activator activity 8/282 271/18639 0.029520295202952 1.95116589463767 0.0545598882727128 0.321082528330567 GO:0004601 peroxidase activity 3/282 57/18639 0.0526315789473684 3.47872340425532 0.0551656617158122 0.321799693342238 GO:0050750 low-density lipoprotein particle receptor binding 2/282 26/18639 0.0769230769230769 5.08428805237316 0.0584255830864906 0.337852284804489 GO:0001786 phosphatidylserine binding 3/282 59/18639 0.0508474576271186 3.36080057699243 0.0599796286541282 0.340909855170899 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/282 59/18639 0.0508474576271186 3.36080057699243 0.0599796286541282 0.340909855170899 GO:0004364 glutathione transferase activity 2/282 27/18639 0.0740740740740741 4.89598108747045 0.0624866739093288 0.349190236552132 GO:0016405 CoA-ligase activity 2/282 27/18639 0.0740740740740741 4.89598108747045 0.0624866739093288 0.349190236552132 GO:0031406 carboxylic acid binding 6/282 187/18639 0.0320855614973262 2.12071908066902 0.0652394164881037 0.361535099704908 GO:0043177 organic acid binding 6/282 189/18639 0.0317460317460317 2.09827760891591 0.0679366741859795 0.373370977964268 GO:0003785 actin monomer binding 2/282 29/18639 0.0689655172413793 4.55832721936904 0.0708833943522797 0.380140784227951 GO:0035250 UDP-galactosyltransferase activity 2/282 29/18639 0.0689655172413793 4.55832721936904 0.0708833943522797 0.380140784227951 GO:0043236 laminin binding 2/282 29/18639 0.0689655172413793 4.55832721936904 0.0708833943522797 0.380140784227951 GO:0016878 acid-thiol ligase activity 2/282 31/18639 0.0645161290322581 4.26424159231297 0.0796218614382056 0.420226490923863 GO:0070325 lipoprotein particle receptor binding 2/282 31/18639 0.0645161290322581 4.26424159231297 0.0796218614382056 0.420226490923863 GO:0008378 galactosyltransferase activity 2/282 32/18639 0.0625 4.13098404255319 0.084110467659342 0.440420952704429 GO:1902936 phosphatidylinositol bisphosphate binding 4/282 111/18639 0.036036036036036 2.38182863714779 0.0880570024825977 0.457483645710371 GO:0097110 scaffold protein binding 3/282 70/18639 0.0428571428571429 2.83267477203647 0.0897283947263169 0.461874182372374 GO:0005200 structural constituent of cytoskeleton 4/282 112/18639 0.0357142857142857 2.3605623100304 0.0902911935464791 0.461874182372374 GO:0015035 protein-disulfide reductase activity 2/282 34/18639 0.0588235294117647 3.88798498122653 0.0933096101996614 0.473670922005915 GO:0019208 phosphatase regulator activity 4/282 117/18639 0.0341880341880342 2.25968357883252 0.101863092620494 0.506302435918549 GO:1990782 protein tyrosine kinase binding 4/282 117/18639 0.0341880341880342 2.25968357883252 0.101863092620494 0.506302435918549 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/282 36/18639 0.0555555555555556 3.67198581560284 0.102783201276698 0.506302435918549 GO:0055106 ubiquitin-protein transferase regulator activity 2/282 36/18639 0.0555555555555556 3.67198581560284 0.102783201276698 0.506302435918549 GO:0015399 primary active transmembrane transporter activity 5/282 166/18639 0.0301204819277108 1.99083568315816 0.107929245572493 0.527742266953733 GO:0016247 channel regulator activity 5/282 168/18639 0.0297619047619048 1.96713525835866 0.112031186488403 0.543801014706481 GO:0141108 transporter regulator activity 5/282 170/18639 0.0294117647058824 1.94399249061327 0.116207527249312 0.550531315138904 GO:0046332 SMAD binding 3/282 79/18639 0.0379746835443038 2.50996498788042 0.117768345220529 0.550531315138904 GO:0005525 GTP binding 9/282 378/18639 0.0238095238095238 1.57370820668693 0.121326333547604 0.550531315138904 GO:0015036 disulfide oxidoreductase activity 2/282 40/18639 0.05 3.30478723404255 0.122456398592562 0.550531315138904 GO:0005126 cytokine receptor binding 7/282 275/18639 0.0254545454545455 1.68243713733075 0.124942405566582 0.550531315138904 GO:0004812 aminoacyl-tRNA ligase activity 2/282 41/18639 0.0487804878048781 3.22418266735859 0.127509199230977 0.550531315138904 GO:0016875 ligase activity, forming carbon-oxygen bonds 2/282 41/18639 0.0487804878048781 3.22418266735859 0.127509199230977 0.550531315138904 GO:0140318 protein transporter activity 2/282 41/18639 0.0487804878048781 3.22418266735859 0.127509199230977 0.550531315138904 GO:0030165 PDZ domain binding 3/282 83/18639 0.036144578313253 2.3890028197898 0.131156366282977 0.550531315138904 GO:0019894 kinesin binding 2/282 42/18639 0.0476190476190476 3.14741641337386 0.132610346243928 0.550531315138904 GO:0030246 carbohydrate binding 7/282 280/18639 0.025 1.65239361702128 0.133583178976404 0.550531315138904 GO:0051117 ATPase binding 3/282 84/18639 0.0357142857142857 2.3605623100304 0.134584013166855 0.550531315138904 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/282 43/18639 0.0465116279069767 3.07422068283028 0.137757234363991 0.550531315138904 GO:0008375 acetylglucosaminyltransferase activity 2/282 43/18639 0.0465116279069767 3.07422068283028 0.137757234363991 0.550531315138904 GO:0004090 carbonyl reductase (NADPH) activity 1/282 10/18639 0.1 6.60957446808511 0.141431633552083 0.550531315138904 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/282 10/18639 0.1 6.60957446808511 0.141431633552083 0.550531315138904 GO:0005528 FK506 binding 1/282 10/18639 0.1 6.60957446808511 0.141431633552083 0.550531315138904 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/282 10/18639 0.1 6.60957446808511 0.141431633552083 0.550531315138904 GO:0015203 polyamine transmembrane transporter activity 1/282 10/18639 0.1 6.60957446808511 0.141431633552083 0.550531315138904 GO:0031434 mitogen-activated protein kinase kinase binding 1/282 10/18639 0.1 6.60957446808511 0.141431633552083 0.550531315138904 GO:0031720 haptoglobin binding 1/282 10/18639 0.1 6.60957446808511 0.141431633552083 0.550531315138904 GO:0031996 thioesterase binding 1/282 10/18639 0.1 6.60957446808511 0.141431633552083 0.550531315138904 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/282 10/18639 0.1 6.60957446808511 0.141431633552083 0.550531315138904 GO:0050308 sugar-phosphatase activity 1/282 10/18639 0.1 6.60957446808511 0.141431633552083 0.550531315138904 GO:0051880 G-quadruplex DNA binding 1/282 10/18639 0.1 6.60957446808511 0.141431633552083 0.550531315138904 GO:0070097 delta-catenin binding 1/282 10/18639 0.1 6.60957446808511 0.141431633552083 0.550531315138904 GO:0005125 cytokine activity 6/282 234/18639 0.0256410256410256 1.69476268412439 0.145002028211752 0.550531315138904 GO:0019207 kinase regulator activity 7/282 287/18639 0.024390243902439 1.61209133367929 0.146163165767123 0.550531315138904 GO:0004197 cysteine-type endopeptidase activity 3/282 88/18639 0.0340909090909091 2.25326402321083 0.148595377837065 0.550531315138904 GO:0015078 proton transmembrane transporter activity 5/282 185/18639 0.027027027027027 1.78637147786084 0.149782943061972 0.550531315138904 GO:0002020 protease binding 4/282 136/18639 0.0294117647058824 1.94399249061327 0.15142676387912 0.550531315138904 GO:0044325 transmembrane transporter binding 4/282 136/18639 0.0294117647058824 1.94399249061327 0.15142676387912 0.550531315138904 GO:0004180 carboxypeptidase activity 2/282 46/18639 0.0434782608695652 2.87372802960222 0.153447292967834 0.550531315138904 GO:0019001 guanyl nucleotide binding 9/282 400/18639 0.0225 1.48715425531915 0.154346723750073 0.550531315138904 GO:0032561 guanyl ribonucleotide binding 9/282 400/18639 0.0225 1.48715425531915 0.154346723750073 0.550531315138904 GO:0000099 sulfur amino acid transmembrane transporter activity 1/282 11/18639 0.0909090909090909 6.00870406189555 0.154428374082348 0.550531315138904 GO:0008199 ferric iron binding 1/282 11/18639 0.0909090909090909 6.00870406189555 0.154428374082348 0.550531315138904 GO:0008503 benzodiazepine receptor activity 1/282 11/18639 0.0909090909090909 6.00870406189555 0.154428374082348 0.550531315138904 GO:0019203 carbohydrate phosphatase activity 1/282 11/18639 0.0909090909090909 6.00870406189555 0.154428374082348 0.550531315138904 GO:0019215 intermediate filament binding 1/282 11/18639 0.0909090909090909 6.00870406189555 0.154428374082348 0.550531315138904 GO:0032050 clathrin heavy chain binding 1/282 11/18639 0.0909090909090909 6.00870406189555 0.154428374082348 0.550531315138904 GO:0034713 type I transforming growth factor beta receptor binding 1/282 11/18639 0.0909090909090909 6.00870406189555 0.154428374082348 0.550531315138904 GO:0043522 leucine zipper domain binding 1/282 11/18639 0.0909090909090909 6.00870406189555 0.154428374082348 0.550531315138904 GO:0070697 activin receptor binding 1/282 11/18639 0.0909090909090909 6.00870406189555 0.154428374082348 0.550531315138904 GO:0070990 snRNP binding 1/282 11/18639 0.0909090909090909 6.00870406189555 0.154428374082348 0.550531315138904 GO:0180030 inositol phosphate kinase activity 1/282 11/18639 0.0909090909090909 6.00870406189555 0.154428374082348 0.550531315138904 GO:1990948 ubiquitin ligase inhibitor activity 1/282 11/18639 0.0909090909090909 6.00870406189555 0.154428374082348 0.550531315138904 GO:0019210 kinase inhibitor activity 3/282 90/18639 0.0333333333333333 2.2031914893617 0.155771356235312 0.550531315138904 GO:0072341 modified amino acid binding 3/282 91/18639 0.032967032967033 2.17898059387421 0.159399382943081 0.550531315138904 GO:0043178 alcohol binding 3/282 92/18639 0.0326086956521739 2.15529602220166 0.163053139011821 0.550531315138904 GO:0052689 carboxylic ester hydrolase activity 3/282 92/18639 0.0326086956521739 2.15529602220166 0.163053139011821 0.550531315138904 GO:0004859 phospholipase inhibitor activity 1/282 12/18639 0.0833333333333333 5.50797872340426 0.167229061139938 0.550531315138904 GO:0004875 complement receptor activity 1/282 12/18639 0.0833333333333333 5.50797872340426 0.167229061139938 0.550531315138904 GO:0005078 MAP-kinase scaffold activity 1/282 12/18639 0.0833333333333333 5.50797872340426 0.167229061139938 0.550531315138904 GO:0005095 GTPase inhibitor activity 1/282 12/18639 0.0833333333333333 5.50797872340426 0.167229061139938 0.550531315138904 GO:0005527 macrolide binding 1/282 12/18639 0.0833333333333333 5.50797872340426 0.167229061139938 0.550531315138904 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/282 12/18639 0.0833333333333333 5.50797872340426 0.167229061139938 0.550531315138904 GO:0016840 carbon-nitrogen lyase activity 1/282 12/18639 0.0833333333333333 5.50797872340426 0.167229061139938 0.550531315138904 GO:0035497 cAMP response element binding 1/282 12/18639 0.0833333333333333 5.50797872340426 0.167229061139938 0.550531315138904 GO:0042301 phosphate ion binding 1/282 12/18639 0.0833333333333333 5.50797872340426 0.167229061139938 0.550531315138904 GO:0045295 gamma-catenin binding 1/282 12/18639 0.0833333333333333 5.50797872340426 0.167229061139938 0.550531315138904 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/282 12/18639 0.0833333333333333 5.50797872340426 0.167229061139938 0.550531315138904 GO:0070410 co-SMAD binding 1/282 12/18639 0.0833333333333333 5.50797872340426 0.167229061139938 0.550531315138904 GO:0097371 MDM2/MDM4 family protein binding 1/282 12/18639 0.0833333333333333 5.50797872340426 0.167229061139938 0.550531315138904 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/282 12/18639 0.0833333333333333 5.50797872340426 0.167229061139938 0.550531315138904 GO:0042562 hormone binding 3/282 94/18639 0.0319148936170213 2.10943866002716 0.17043496512798 0.557285964574144 GO:0033218 amide binding 6/282 247/18639 0.0242914979757085 1.60556464811784 0.172590593374609 0.557285964574144 GO:0042277 peptide binding 6/282 249/18639 0.0240963855421687 1.59266854652653 0.17701760324662 0.557285964574144 GO:0008194 UDP-glycosyltransferase activity 4/282 145/18639 0.0275862068965517 1.82333088774762 0.177579472051655 0.557285964574144 GO:0016758 hexosyltransferase activity 5/282 197/18639 0.0253807106598985 1.6775569715952 0.179246125742522 0.557285964574144 GO:0008253 5'-nucleotidase activity 1/282 13/18639 0.0769230769230769 5.08428805237316 0.179836641789454 0.557285964574144 GO:0039706 co-receptor binding 1/282 13/18639 0.0769230769230769 5.08428805237316 0.179836641789454 0.557285964574144 GO:0043560 insulin receptor substrate binding 1/282 13/18639 0.0769230769230769 5.08428805237316 0.179836641789454 0.557285964574144 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/282 13/18639 0.0769230769230769 5.08428805237316 0.179836641789454 0.557285964574144 GO:0089720 caspase binding 1/282 13/18639 0.0769230769230769 5.08428805237316 0.179836641789454 0.557285964574144 GO:0008170 N-methyltransferase activity 3/282 98/18639 0.0306122448979592 2.0233391228832 0.185475907156288 0.557285964574144 GO:0042626 ATPase-coupled transmembrane transporter activity 3/282 98/18639 0.0306122448979592 2.0233391228832 0.185475907156288 0.557285964574144 GO:0004864 protein phosphatase inhibitor activity 2/282 53/18639 0.0377358490566038 2.49417904456042 0.191215014496158 0.557285964574144 GO:0005544 calcium-dependent phospholipid binding 2/282 53/18639 0.0377358490566038 2.49417904456042 0.191215014496158 0.557285964574144 GO:0016860 intramolecular oxidoreductase activity 2/282 53/18639 0.0377358490566038 2.49417904456042 0.191215014496158 0.557285964574144 GO:0005161 platelet-derived growth factor receptor binding 1/282 14/18639 0.0714285714285714 4.72112462006079 0.192254018951237 0.557285964574144 GO:0005313 L-glutamate transmembrane transporter activity 1/282 14/18639 0.0714285714285714 4.72112462006079 0.192254018951237 0.557285964574144 GO:0005344 oxygen carrier activity 1/282 14/18639 0.0714285714285714 4.72112462006079 0.192254018951237 0.557285964574144 GO:0005545 1-phosphatidylinositol binding 1/282 14/18639 0.0714285714285714 4.72112462006079 0.192254018951237 0.557285964574144 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/282 14/18639 0.0714285714285714 4.72112462006079 0.192254018951237 0.557285964574144 GO:0042043 neurexin family protein binding 1/282 14/18639 0.0714285714285714 4.72112462006079 0.192254018951237 0.557285964574144 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/282 14/18639 0.0714285714285714 4.72112462006079 0.192254018951237 0.557285964574144 GO:0019842 vitamin binding 4/282 150/18639 0.0266666666666667 1.76255319148936 0.192726770242745 0.557285964574144 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/282 54/18639 0.037037037037037 2.44799054373522 0.196711356322724 0.557285964574144 GO:0098632 cell-cell adhesion mediator activity 2/282 55/18639 0.0363636363636364 2.40348162475822 0.20222703289828 0.557285964574144 GO:0004129 cytochrome-c oxidase activity 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0005523 tropomyosin binding 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0008252 nucleotidase activity 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0016846 carbon-sulfur lyase activity 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0034483 heparan sulfate sulfotransferase activity 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0047372 monoacylglycerol lipase activity 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0048531 beta-1,3-galactosyltransferase activity 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0050700 CARD domain binding 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0050780 dopamine receptor binding 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0051371 muscle alpha-actinin binding 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0061578 K63-linked deubiquitinase activity 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0120283 protein serine/threonine kinase binding 1/282 15/18639 0.0666666666666667 4.4063829787234 0.20448405206027 0.557285964574144 GO:0005516 calmodulin binding 5/282 207/18639 0.0241545893719807 1.59651557200123 0.205315881685211 0.557285964574144 GO:0019212 phosphatase inhibitor activity 2/282 56/18639 0.0357142857142857 2.3605623100304 0.207760209507933 0.560448529009634 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/282 16/18639 0.0625 4.13098404255319 0.216529557715286 0.560448529009634 GO:0008142 oxysterol binding 1/282 16/18639 0.0625 4.13098404255319 0.216529557715286 0.560448529009634 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/282 16/18639 0.0625 4.13098404255319 0.216529557715286 0.560448529009634 GO:0016722 oxidoreductase activity, acting on metal ions 1/282 16/18639 0.0625 4.13098404255319 0.216529557715286 0.560448529009634 GO:0030275 LRR domain binding 1/282 16/18639 0.0625 4.13098404255319 0.216529557715286 0.560448529009634 GO:0055102 lipase inhibitor activity 1/282 16/18639 0.0625 4.13098404255319 0.216529557715286 0.560448529009634 GO:0070411 I-SMAD binding 1/282 16/18639 0.0625 4.13098404255319 0.216529557715286 0.560448529009634 GO:0097027 ubiquitin-protein transferase activator activity 1/282 16/18639 0.0625 4.13098404255319 0.216529557715286 0.560448529009634 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/282 16/18639 0.0625 4.13098404255319 0.216529557715286 0.560448529009634 GO:0016757 glycosyltransferase activity 6/282 267/18639 0.0224719101123595 1.48529763327755 0.218803590658065 0.560448529009634 GO:0019888 protein phosphatase regulator activity 3/282 107/18639 0.0280373831775701 1.85315172002386 0.220465447520685 0.560448529009634 GO:0099106 ion channel regulator activity 4/282 160/18639 0.025 1.65239361702128 0.224141757786225 0.560448529009634 GO:0005496 steroid binding 3/282 108/18639 0.0277777777777778 1.83599290780142 0.224435348256244 0.560448529009634 GO:0015459 potassium channel regulator activity 2/282 59/18639 0.0338983050847458 2.24053371799495 0.224447146553438 0.560448529009634 GO:0045309 protein phosphorylated amino acid binding 2/282 59/18639 0.0338983050847458 2.24053371799495 0.224447146553438 0.560448529009634 GO:0070888 E-box binding 2/282 59/18639 0.0338983050847458 2.24053371799495 0.224447146553438 0.560448529009634 GO:0004866 endopeptidase inhibitor activity 4/282 161/18639 0.0248447204968944 1.64213030262984 0.227355389994795 0.560448529009634 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/282 17/18639 0.0588235294117647 3.88798498122653 0.228393310318212 0.560448529009634 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/282 17/18639 0.0588235294117647 3.88798498122653 0.228393310318212 0.560448529009634 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/282 17/18639 0.0588235294117647 3.88798498122653 0.228393310318212 0.560448529009634 GO:0008429 phosphatidylethanolamine binding 1/282 17/18639 0.0588235294117647 3.88798498122653 0.228393310318212 0.560448529009634 GO:0030169 low-density lipoprotein particle binding 1/282 17/18639 0.0588235294117647 3.88798498122653 0.228393310318212 0.560448529009634 GO:0031489 myosin V binding 1/282 17/18639 0.0588235294117647 3.88798498122653 0.228393310318212 0.560448529009634 GO:0051787 misfolded protein binding 1/282 17/18639 0.0588235294117647 3.88798498122653 0.228393310318212 0.560448529009634 GO:0070492 oligosaccharide binding 1/282 17/18639 0.0588235294117647 3.88798498122653 0.228393310318212 0.560448529009634 GO:0016791 phosphatase activity 6/282 273/18639 0.021978021978022 1.45265372924947 0.233425492750382 0.570185351422269 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/282 61/18639 0.0327868852459016 2.16707359609348 0.235627867013203 0.570185351422269 GO:0000400 four-way junction DNA binding 1/282 18/18639 0.0555555555555556 3.67198581560284 0.240078042704113 0.570185351422269 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/282 18/18639 0.0555555555555556 3.67198581560284 0.240078042704113 0.570185351422269 GO:0015172 acidic amino acid transmembrane transporter activity 1/282 18/18639 0.0555555555555556 3.67198581560284 0.240078042704113 0.570185351422269 GO:0031690 adrenergic receptor binding 1/282 18/18639 0.0555555555555556 3.67198581560284 0.240078042704113 0.570185351422269 GO:0035615 clathrin adaptor activity 1/282 18/18639 0.0555555555555556 3.67198581560284 0.240078042704113 0.570185351422269 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/282 18/18639 0.0555555555555556 3.67198581560284 0.240078042704113 0.570185351422269 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/282 18/18639 0.0555555555555556 3.67198581560284 0.240078042704113 0.570185351422269 GO:0005507 copper ion binding 2/282 63/18639 0.0317460317460317 2.09827760891591 0.24683870741133 0.584155659888024 GO:0140036 ubiquitin-modified protein reader activity 1/282 19/18639 0.0526315789473684 3.47872340425532 0.25158644676176 0.587283354229953 GO:1990380 K48-linked deubiquitinase activity 1/282 19/18639 0.0526315789473684 3.47872340425532 0.25158644676176 0.587283354229953 GO:0017124 SH3 domain binding 3/282 115/18639 0.0260869565217391 1.72423681776133 0.252581071310891 0.587283354229953 GO:0035401 histone H3Y41 kinase activity 3/282 115/18639 0.0260869565217391 1.72423681776133 0.252581071310891 0.587283354229953 GO:0140801 histone H2AXY142 kinase activity 3/282 115/18639 0.0260869565217391 1.72423681776133 0.252581071310891 0.587283354229953 GO:0030414 peptidase inhibitor activity 4/282 169/18639 0.0236686390532544 1.56439632380713 0.253459131825559 0.587283354229953 GO:0000339 RNA cap binding 1/282 20/18639 0.05 3.30478723404255 0.26292117404496 0.600833610790029 GO:0030742 GTP-dependent protein binding 1/282 20/18639 0.05 3.30478723404255 0.26292117404496 0.600833610790029 GO:0031418 L-ascorbic acid binding 1/282 20/18639 0.05 3.30478723404255 0.26292117404496 0.600833610790029 GO:0140664 ATP-dependent DNA damage sensor activity 1/282 20/18639 0.05 3.30478723404255 0.26292117404496 0.600833610790029 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/282 67/18639 0.0298507462686567 1.973007303906 0.269304045401093 0.607384735077643 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/282 21/18639 0.0476190476190476 3.14741641337386 0.274084836374802 0.607384735077643 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/282 21/18639 0.0476190476190476 3.14741641337386 0.274084836374802 0.607384735077643 GO:0019200 carbohydrate kinase activity 1/282 21/18639 0.0476190476190476 3.14741641337386 0.274084836374802 0.607384735077643 GO:0051010 microtubule plus-end binding 1/282 21/18639 0.0476190476190476 3.14741641337386 0.274084836374802 0.607384735077643 GO:0072542 protein phosphatase activator activity 1/282 21/18639 0.0476190476190476 3.14741641337386 0.274084836374802 0.607384735077643 GO:0140312 cargo adaptor activity 1/282 21/18639 0.0476190476190476 3.14741641337386 0.274084836374802 0.607384735077643 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 2/282 68/18639 0.0294117647058824 1.94399249061327 0.274921511666723 0.607384735077643 GO:0030145 manganese ion binding 2/282 68/18639 0.0294117647058824 1.94399249061327 0.274921511666723 0.607384735077643 GO:0032934 sterol binding 2/282 68/18639 0.0294117647058824 1.94399249061327 0.274921511666723 0.607384735077643 GO:0003697 single-stranded DNA binding 3/282 121/18639 0.0247933884297521 1.63873747142606 0.277089658302463 0.60813406855161 GO:0051082 unfolded protein binding 3/282 121/18639 0.0247933884297521 1.63873747142606 0.277089658302463 0.60813406855161 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/282 22/18639 0.0454545454545455 3.00435203094778 0.285080006432934 0.613347071337845 GO:0050321 tau-protein kinase activity 1/282 22/18639 0.0454545454545455 3.00435203094778 0.285080006432934 0.613347071337845 GO:0070034 telomerase RNA binding 1/282 22/18639 0.0454545454545455 3.00435203094778 0.285080006432934 0.613347071337845 GO:0140035 ubiquitin-like protein reader activity 1/282 22/18639 0.0454545454545455 3.00435203094778 0.285080006432934 0.613347071337845 GO:0140299 molecular sensor activity 2/282 71/18639 0.028169014084507 1.86185196284088 0.291756372078245 0.613347071337845 GO:0005158 insulin receptor binding 1/282 23/18639 0.0434782608695652 2.87372802960222 0.29590921834602 0.613347071337845 GO:0017134 fibroblast growth factor binding 1/282 23/18639 0.0434782608695652 2.87372802960222 0.29590921834602 0.613347071337845 GO:0042171 lysophosphatidic acid acyltransferase activity 1/282 23/18639 0.0434782608695652 2.87372802960222 0.29590921834602 0.613347071337845 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/282 23/18639 0.0434782608695652 2.87372802960222 0.29590921834602 0.613347071337845 GO:0071617 lysophospholipid acyltransferase activity 1/282 23/18639 0.0434782608695652 2.87372802960222 0.29590921834602 0.613347071337845 GO:0043539 protein serine/threonine kinase activator activity 2/282 73/18639 0.0273972602739726 1.81084232002332 0.302953277826139 0.613347071337845 GO:0061135 endopeptidase regulator activity 4/282 184/18639 0.0217391304347826 1.43686401480111 0.30383797779908 0.613347071337845 GO:0031490 chromatin DNA binding 3/282 128/18639 0.0234375 1.54911901595745 0.305953199753352 0.613347071337845 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/282 24/18639 0.0416666666666667 2.75398936170213 0.306574968261491 0.613347071337845 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/282 24/18639 0.0416666666666667 2.75398936170213 0.306574968261491 0.613347071337845 GO:0004622 lysophospholipase activity 1/282 24/18639 0.0416666666666667 2.75398936170213 0.306574968261491 0.613347071337845 GO:0004806 triacylglycerol lipase activity 1/282 24/18639 0.0416666666666667 2.75398936170213 0.306574968261491 0.613347071337845 GO:0005540 hyaluronic acid binding 1/282 24/18639 0.0416666666666667 2.75398936170213 0.306574968261491 0.613347071337845 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/282 24/18639 0.0416666666666667 2.75398936170213 0.306574968261491 0.613347071337845 GO:0030552 cAMP binding 1/282 24/18639 0.0416666666666667 2.75398936170213 0.306574968261491 0.613347071337845 GO:0035035 histone acetyltransferase binding 1/282 24/18639 0.0416666666666667 2.75398936170213 0.306574968261491 0.613347071337845 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/282 24/18639 0.0416666666666667 2.75398936170213 0.306574968261491 0.613347071337845 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/282 24/18639 0.0416666666666667 2.75398936170213 0.306574968261491 0.613347071337845 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/282 24/18639 0.0416666666666667 2.75398936170213 0.306574968261491 0.613347071337845 GO:0048027 mRNA 5'-UTR binding 1/282 24/18639 0.0416666666666667 2.75398936170213 0.306574968261491 0.613347071337845 GO:0050431 transforming growth factor beta binding 1/282 24/18639 0.0416666666666667 2.75398936170213 0.306574968261491 0.613347071337845 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/282 24/18639 0.0416666666666667 2.75398936170213 0.306574968261491 0.613347071337845 GO:0140612 DNA damage sensor activity 1/282 24/18639 0.0416666666666667 2.75398936170213 0.306574968261491 0.613347071337845 GO:0048029 monosaccharide binding 2/282 74/18639 0.027027027027027 1.78637147786084 0.308540502274117 0.613347071337845 GO:0042578 phosphoric ester hydrolase activity 7/282 363/18639 0.0192837465564738 1.27457358888694 0.311276932433407 0.613347071337845 GO:0008234 cysteine-type peptidase activity 4/282 187/18639 0.0213903743315508 1.41381272044601 0.314063227925741 0.613347071337845 GO:0019003 GDP binding 2/282 75/18639 0.0266666666666667 1.76255319148936 0.31411884237374 0.613347071337845 GO:0003707 nuclear steroid receptor activity 1/282 25/18639 0.04 2.64382978723404 0.317079714914742 0.613347071337845 GO:0004709 MAP kinase kinase kinase activity 1/282 25/18639 0.04 2.64382978723404 0.317079714914742 0.613347071337845 GO:0008139 nuclear localization sequence binding 1/282 25/18639 0.04 2.64382978723404 0.317079714914742 0.613347071337845 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/282 25/18639 0.04 2.64382978723404 0.317079714914742 0.613347071337845 GO:0017056 structural constituent of nuclear pore 1/282 25/18639 0.04 2.64382978723404 0.317079714914742 0.613347071337845 GO:0019211 phosphatase activator activity 1/282 25/18639 0.04 2.64382978723404 0.317079714914742 0.613347071337845 GO:0047617 fatty acyl-CoA hydrolase activity 1/282 25/18639 0.04 2.64382978723404 0.317079714914742 0.613347071337845 GO:0120020 cholesterol transfer activity 1/282 25/18639 0.04 2.64382978723404 0.317079714914742 0.613347071337845 GO:0017022 myosin binding 2/282 76/18639 0.0263157894736842 1.73936170212766 0.319687290589854 0.613347071337845 GO:0098631 cell adhesion mediator activity 2/282 76/18639 0.0263157894736842 1.73936170212766 0.319687290589854 0.613347071337845 GO:0019902 phosphatase binding 4/282 190/18639 0.0210526315789474 1.39148936170213 0.324318974128791 0.613347071337845 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/282 26/18639 0.0384615384615385 2.54214402618658 0.327425880187872 0.613347071337845 GO:0005160 transforming growth factor beta receptor binding 1/282 26/18639 0.0384615384615385 2.54214402618658 0.327425880187872 0.613347071337845 GO:0008198 ferrous iron binding 1/282 26/18639 0.0384615384615385 2.54214402618658 0.327425880187872 0.613347071337845 GO:0016289 acyl-CoA hydrolase activity 1/282 26/18639 0.0384615384615385 2.54214402618658 0.327425880187872 0.613347071337845 GO:0030507 spectrin binding 1/282 26/18639 0.0384615384615385 2.54214402618658 0.327425880187872 0.613347071337845 GO:0043548 phosphatidylinositol 3-kinase binding 1/282 26/18639 0.0384615384615385 2.54214402618658 0.327425880187872 0.613347071337845 GO:0050681 nuclear androgen receptor binding 1/282 26/18639 0.0384615384615385 2.54214402618658 0.327425880187872 0.613347071337845 GO:0052742 phosphatidylinositol kinase activity 1/282 26/18639 0.0384615384615385 2.54214402618658 0.327425880187872 0.613347071337845 GO:0070412 R-SMAD binding 1/282 26/18639 0.0384615384615385 2.54214402618658 0.327425880187872 0.613347071337845 GO:0001671 ATPase activator activity 1/282 27/18639 0.037037037037037 2.44799054373522 0.337615849660124 0.620205911668459 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/282 27/18639 0.037037037037037 2.44799054373522 0.337615849660124 0.620205911668459 GO:0008320 protein transmembrane transporter activity 1/282 27/18639 0.037037037037037 2.44799054373522 0.337615849660124 0.620205911668459 GO:0015252 proton channel activity 1/282 27/18639 0.037037037037037 2.44799054373522 0.337615849660124 0.620205911668459 GO:0023026 MHC class II protein complex binding 1/282 27/18639 0.037037037037037 2.44799054373522 0.337615849660124 0.620205911668459 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/282 27/18639 0.037037037037037 2.44799054373522 0.337615849660124 0.620205911668459 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/282 27/18639 0.037037037037037 2.44799054373522 0.337615849660124 0.620205911668459 GO:0030971 receptor tyrosine kinase binding 2/282 81/18639 0.0246913580246914 1.63199369582348 0.347348109645845 0.621474629421589 GO:0005242 inward rectifier potassium channel activity 1/282 28/18639 0.0357142857142857 2.3605623100304 0.347651973150122 0.621474629421589 GO:0019789 SUMO transferase activity 1/282 28/18639 0.0357142857142857 2.3605623100304 0.347651973150122 0.621474629421589 GO:0046875 ephrin receptor binding 1/282 28/18639 0.0357142857142857 2.3605623100304 0.347651973150122 0.621474629421589 GO:0050698 proteoglycan sulfotransferase activity 1/282 28/18639 0.0357142857142857 2.3605623100304 0.347651973150122 0.621474629421589 GO:0051019 mitogen-activated protein kinase binding 1/282 28/18639 0.0357142857142857 2.3605623100304 0.347651973150122 0.621474629421589 GO:0051393 alpha-actinin binding 1/282 28/18639 0.0357142857142857 2.3605623100304 0.347651973150122 0.621474629421589 GO:0051537 2 iron, 2 sulfur cluster binding 1/282 28/18639 0.0357142857142857 2.3605623100304 0.347651973150122 0.621474629421589 GO:0051959 dynein light intermediate chain binding 1/282 28/18639 0.0357142857142857 2.3605623100304 0.347651973150122 0.621474629421589 GO:0141052 histone H3 demethylase activity 1/282 28/18639 0.0357142857142857 2.3605623100304 0.347651973150122 0.621474629421589 GO:0030295 protein kinase activator activity 3/282 139/18639 0.0215827338129496 1.42652686361549 0.351477596413873 0.625450403577596 GO:0017171 serine hydrolase activity 4/282 198/18639 0.0202020202020202 1.33526756931012 0.351757069079731 0.625450403577596 GO:0004713 protein tyrosine kinase activity 3/282 140/18639 0.0214285714285714 1.41633738601824 0.355607855815748 0.630611264313259 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/282 29/18639 0.0344827586206897 2.27916360968452 0.357536565250045 0.630667946661219 GO:0051861 glycolipid binding 1/282 29/18639 0.0344827586206897 2.27916360968452 0.357536565250045 0.630667946661219 GO:0001965 G-protein alpha-subunit binding 1/282 30/18639 0.0333333333333333 2.2031914893617 0.367271905851844 0.634378746471367 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/282 30/18639 0.0333333333333333 2.2031914893617 0.367271905851844 0.634378746471367 GO:0031624 ubiquitin conjugating enzyme binding 1/282 30/18639 0.0333333333333333 2.2031914893617 0.367271905851844 0.634378746471367 GO:0032452 histone demethylase activity 1/282 30/18639 0.0333333333333333 2.2031914893617 0.367271905851844 0.634378746471367 GO:0033612 receptor serine/threonine kinase binding 1/282 30/18639 0.0333333333333333 2.2031914893617 0.367271905851844 0.634378746471367 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/282 30/18639 0.0333333333333333 2.2031914893617 0.367271905851844 0.634378746471367 GO:0048019 receptor antagonist activity 1/282 30/18639 0.0333333333333333 2.2031914893617 0.367271905851844 0.634378746471367 GO:0051721 protein phosphatase 2A binding 1/282 30/18639 0.0333333333333333 2.2031914893617 0.367271905851844 0.634378746471367 GO:0019903 protein phosphatase binding 3/282 144/18639 0.0208333333333333 1.37699468085106 0.372091323082547 0.639316479700626 GO:0005164 tumor necrosis factor receptor binding 1/282 31/18639 0.032258064516129 2.13212079615649 0.376860240665632 0.639316479700626 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/282 31/18639 0.032258064516129 2.13212079615649 0.376860240665632 0.639316479700626 GO:0016411 acylglycerol O-acyltransferase activity 1/282 31/18639 0.032258064516129 2.13212079615649 0.376860240665632 0.639316479700626 GO:0047499 calcium-independent phospholipase A2 activity 1/282 31/18639 0.032258064516129 2.13212079615649 0.376860240665632 0.639316479700626 GO:0072349 modified amino acid transmembrane transporter activity 1/282 31/18639 0.032258064516129 2.13212079615649 0.376860240665632 0.639316479700626 GO:0140457 protein demethylase activity 1/282 31/18639 0.032258064516129 2.13212079615649 0.376860240665632 0.639316479700626 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 5/282 268/18639 0.0186567164179104 1.23312956494125 0.381984370942074 0.640628465961804 GO:0022884 macromolecule transmembrane transporter activity 1/282 32/18639 0.03125 2.0654920212766 0.386303781730351 0.640628465961804 GO:0030515 snoRNA binding 1/282 32/18639 0.03125 2.0654920212766 0.386303781730351 0.640628465961804 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/282 32/18639 0.03125 2.0654920212766 0.386303781730351 0.640628465961804 GO:0043425 bHLH transcription factor binding 1/282 32/18639 0.03125 2.0654920212766 0.386303781730351 0.640628465961804 GO:0047498 calcium-dependent phospholipase A2 activity 1/282 32/18639 0.03125 2.0654920212766 0.386303781730351 0.640628465961804 GO:0071813 lipoprotein particle binding 1/282 32/18639 0.03125 2.0654920212766 0.386303781730351 0.640628465961804 GO:0071814 protein-lipid complex binding 1/282 32/18639 0.03125 2.0654920212766 0.386303781730351 0.640628465961804 GO:0120015 sterol transfer activity 1/282 32/18639 0.03125 2.0654920212766 0.386303781730351 0.640628465961804 GO:0019209 kinase activator activity 3/282 148/18639 0.0202702702702703 1.33977860839563 0.388495072230675 0.642659758789549 GO:0071889 14-3-3 protein binding 1/282 33/18639 0.0303030303030303 2.00290135396518 0.395604707916842 0.651181016744307 GO:0140311 protein sequestering activity 1/282 33/18639 0.0303030303030303 2.00290135396518 0.395604707916842 0.651181016744307 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/282 91/18639 0.021978021978022 1.45265372924947 0.401434624239449 0.653322415064506 GO:0008376 acetylgalactosaminyltransferase activity 1/282 34/18639 0.0294117647058824 1.94399249061327 0.404765165423423 0.653322415064506 GO:0015020 glucuronosyltransferase activity 1/282 34/18639 0.0294117647058824 1.94399249061327 0.404765165423423 0.653322415064506 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/282 34/18639 0.0294117647058824 1.94399249061327 0.404765165423423 0.653322415064506 GO:0019825 oxygen binding 1/282 34/18639 0.0294117647058824 1.94399249061327 0.404765165423423 0.653322415064506 GO:0030332 cyclin binding 1/282 34/18639 0.0294117647058824 1.94399249061327 0.404765165423423 0.653322415064506 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/282 34/18639 0.0294117647058824 1.94399249061327 0.404765165423423 0.653322415064506 GO:0090482 vitamin transmembrane transporter activity 1/282 34/18639 0.0294117647058824 1.94399249061327 0.404765165423423 0.653322415064506 GO:0001217 DNA-binding transcription repressor activity 5/282 278/18639 0.0179856115107914 1.18877238634624 0.411924581809449 0.657875884953455 GO:0051213 dioxygenase activity 2/282 93/18639 0.021505376344086 1.42141386410432 0.412006717726696 0.657875884953455 GO:0051219 phosphoprotein binding 2/282 93/18639 0.021505376344086 1.42141386410432 0.412006717726696 0.657875884953455 GO:0004623 phospholipase A2 activity 1/282 35/18639 0.0285714285714286 1.88844984802432 0.41378726826409 0.657875884953455 GO:0016229 steroid dehydrogenase activity 1/282 35/18639 0.0285714285714286 1.88844984802432 0.41378726826409 0.657875884953455 GO:0140566 histone reader activity 1/282 35/18639 0.0285714285714286 1.88844984802432 0.41378726826409 0.657875884953455 GO:0004175 endopeptidase activity 7/282 405/18639 0.0172839506172839 1.14239558707644 0.414511271872929 0.657875884953455 GO:0008276 protein methyltransferase activity 2/282 95/18639 0.0210526315789474 1.39148936170213 0.422486163007692 0.659806597813099 GO:0004033 aldo-keto reductase (NADPH) activity 1/282 36/18639 0.0277777777777778 1.83599290780142 0.422673098749444 0.659806597813099 GO:0005484 SNAP receptor activity 1/282 36/18639 0.0277777777777778 1.83599290780142 0.422673098749444 0.659806597813099 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/282 36/18639 0.0277777777777778 1.83599290780142 0.422673098749444 0.659806597813099 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/282 36/18639 0.0277777777777778 1.83599290780142 0.422673098749444 0.659806597813099 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/282 36/18639 0.0277777777777778 1.83599290780142 0.422673098749444 0.659806597813099 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/282 36/18639 0.0277777777777778 1.83599290780142 0.422673098749444 0.659806597813099 GO:0030280 structural constituent of skin epidermis 1/282 37/18639 0.027027027027027 1.78637147786084 0.431424707960467 0.665655291864757 GO:0030551 cyclic nucleotide binding 1/282 37/18639 0.027027027027027 1.78637147786084 0.431424707960467 0.665655291864757 GO:0042805 actinin binding 1/282 37/18639 0.027027027027027 1.78637147786084 0.431424707960467 0.665655291864757 GO:0043394 proteoglycan binding 1/282 37/18639 0.027027027027027 1.78637147786084 0.431424707960467 0.665655291864757 GO:0070001 aspartic-type peptidase activity 1/282 37/18639 0.027027027027027 1.78637147786084 0.431424707960467 0.665655291864757 GO:0030527 structural constituent of chromatin 2/282 98/18639 0.0204081632653061 1.3488927485888 0.438023006899082 0.67386278592147 GO:0019787 ubiquitin-like protein transferase activity 8/282 479/18639 0.0167014613778706 1.10389552702883 0.438770806472175 0.67386278592147 GO:0000146 microfilament motor activity 1/282 38/18639 0.0263157894736842 1.73936170212766 0.440044116215232 0.674127448508163 GO:0005178 integrin binding 3/282 161/18639 0.0186335403726708 1.23159772697238 0.440970586618121 0.674127448508163 GO:0061134 peptidase regulator activity 4/282 226/18639 0.0176991150442478 1.16983618904161 0.447090581062655 0.679441124137966 GO:0043130 ubiquitin binding 2/282 100/18639 0.02 1.32191489361702 0.448254134921993 0.679441124137966 GO:0000217 DNA secondary structure binding 1/282 39/18639 0.0256410256410256 1.69476268412439 0.448533313528672 0.679441124137966 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/282 39/18639 0.0256410256410256 1.69476268412439 0.448533313528672 0.679441124137966 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/282 40/18639 0.025 1.65239361702128 0.456894260065496 0.68431234897197 GO:0032451 demethylase activity 1/282 40/18639 0.025 1.65239361702128 0.456894260065496 0.68431234897197 GO:0061791 GTPase motor activity 1/282 40/18639 0.025 1.65239361702128 0.456894260065496 0.68431234897197 GO:0071855 neuropeptide receptor binding 1/282 40/18639 0.025 1.65239361702128 0.456894260065496 0.68431234897197 GO:1990606 membrane scission GTPase motor activity 1/282 40/18639 0.025 1.65239361702128 0.456894260065496 0.68431234897197 GO:0008238 exopeptidase activity 2/282 102/18639 0.0196078431372549 1.29599499374218 0.45838006801378 0.684315729159134 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 3/282 167/18639 0.0179640718562874 1.18734870684164 0.464616847213822 0.684315729159134 GO:0001530 lipopolysaccharide binding 1/282 41/18639 0.024390243902439 1.61209133367929 0.465128886586359 0.684315729159134 GO:0001727 lipid kinase activity 1/282 41/18639 0.024390243902439 1.61209133367929 0.465128886586359 0.684315729159134 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/282 41/18639 0.024390243902439 1.61209133367929 0.465128886586359 0.684315729159134 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/282 41/18639 0.024390243902439 1.61209133367929 0.465128886586359 0.684315729159134 GO:0017080 sodium channel regulator activity 1/282 41/18639 0.024390243902439 1.61209133367929 0.465128886586359 0.684315729159134 GO:0042287 MHC protein binding 1/282 41/18639 0.024390243902439 1.61209133367929 0.465128886586359 0.684315729159134 GO:0008307 structural constituent of muscle 1/282 42/18639 0.0238095238095238 1.57370820668693 0.473239094887394 0.688630192779249 GO:0016859 cis-trans isomerase activity 1/282 42/18639 0.0238095238095238 1.57370820668693 0.473239094887394 0.688630192779249 GO:0031492 nucleosomal DNA binding 1/282 42/18639 0.0238095238095238 1.57370820668693 0.473239094887394 0.688630192779249 GO:0042056 chemoattractant activity 1/282 42/18639 0.0238095238095238 1.57370820668693 0.473239094887394 0.688630192779249 GO:0051879 Hsp90 protein binding 1/282 42/18639 0.0238095238095238 1.57370820668693 0.473239094887394 0.688630192779249 GO:0016755 aminoacyltransferase activity 8/282 496/18639 0.0161290322580645 1.06606039807824 0.477520201078752 0.689962650291138 GO:0000149 SNARE binding 2/282 106/18639 0.0188679245283019 1.24708952228021 0.478304935013857 0.689962650291138 GO:0004497 monooxygenase activity 2/282 106/18639 0.0188679245283019 1.24708952228021 0.478304935013857 0.689962650291138 GO:0008013 beta-catenin binding 2/282 106/18639 0.0188679245283019 1.24708952228021 0.478304935013857 0.689962650291138 GO:0008200 ion channel inhibitor activity 1/282 43/18639 0.0232558139534884 1.53711034141514 0.481226758233189 0.691178821220455 GO:0048156 tau protein binding 1/282 43/18639 0.0232558139534884 1.53711034141514 0.481226758233189 0.691178821220455 GO:0004843 cysteine-type deubiquitinase activity 2/282 108/18639 0.0185185185185185 1.22399527186761 0.488098820235566 0.693491098050977 GO:0003954 NADH dehydrogenase activity 1/282 44/18639 0.0227272727272727 1.50217601547389 0.48909372178332 0.693491098050977 GO:0016248 channel inhibitor activity 1/282 44/18639 0.0227272727272727 1.50217601547389 0.48909372178332 0.693491098050977 GO:0016790 thiolester hydrolase activity 1/282 44/18639 0.0227272727272727 1.50217601547389 0.48909372178332 0.693491098050977 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/282 44/18639 0.0227272727272727 1.50217601547389 0.48909372178332 0.693491098050977 GO:0043014 alpha-tubulin binding 1/282 44/18639 0.0227272727272727 1.50217601547389 0.48909372178332 0.693491098050977 GO:0042605 peptide antigen binding 1/282 45/18639 0.0222222222222222 1.46879432624113 0.496841803012527 0.696307496994667 GO:0140303 intramembrane lipid transporter activity 1/282 45/18639 0.0222222222222222 1.46879432624113 0.496841803012527 0.696307496994667 GO:0141110 transporter inhibitor activity 1/282 45/18639 0.0222222222222222 1.46879432624113 0.496841803012527 0.696307496994667 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/282 46/18639 0.0217391304347826 1.43686401480111 0.504472792124631 0.696307496994667 GO:0030276 clathrin binding 1/282 46/18639 0.0217391304347826 1.43686401480111 0.504472792124631 0.696307496994667 GO:0030291 protein serine/threonine kinase inhibitor activity 1/282 46/18639 0.0217391304347826 1.43686401480111 0.504472792124631 0.696307496994667 GO:0005319 lipid transporter activity 3/282 178/18639 0.0168539325842697 1.11397322495816 0.50677607327626 0.696307496994667 GO:0001784 phosphotyrosine residue binding 1/282 47/18639 0.0212765957446809 1.40629244001811 0.511988452460287 0.696307496994667 GO:0043495 protein-membrane adaptor activity 1/282 47/18639 0.0212765957446809 1.40629244001811 0.511988452460287 0.696307496994667 GO:0140359 ABC-type transporter activity 1/282 47/18639 0.0212765957446809 1.40629244001811 0.511988452460287 0.696307496994667 GO:0140938 histone H3 methyltransferase activity 1/282 47/18639 0.0212765957446809 1.40629244001811 0.511988452460287 0.696307496994667 GO:0016853 isomerase activity 3/282 180/18639 0.0166666666666667 1.10159574468085 0.514257396534953 0.696307496994667 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/282 181/18639 0.0165745856353591 1.0955095803456 0.517975476179238 0.696307496994667 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/282 48/18639 0.0208333333333333 1.37699468085106 0.519390520898659 0.696307496994667 GO:0032266 phosphatidylinositol-3-phosphate binding 1/282 48/18639 0.0208333333333333 1.37699468085106 0.519390520898659 0.696307496994667 GO:0038187 pattern recognition receptor activity 1/282 48/18639 0.0208333333333333 1.37699468085106 0.519390520898659 0.696307496994667 GO:0140693 molecular condensate scaffold activity 1/282 48/18639 0.0208333333333333 1.37699468085106 0.519390520898659 0.696307496994667 GO:0004842 ubiquitin-protein transferase activity 7/282 449/18639 0.0155902004454343 1.03044590816472 0.521430064524204 0.696307496994667 GO:0001221 transcription coregulator binding 2/282 115/18639 0.0173913043478261 1.14949121184089 0.521457193625001 0.696307496994667 GO:0101005 deubiquitinase activity 2/282 115/18639 0.0173913043478261 1.14949121184089 0.521457193625001 0.696307496994667 GO:0009055 electron transfer activity 2/282 116/18639 0.0172413793103448 1.13958180484226 0.526103016753932 0.696307496994667 GO:0001222 transcription corepressor binding 1/282 49/18639 0.0204081632653061 1.3488927485888 0.526680708253109 0.696307496994667 GO:0005004 GPI-linked ephrin receptor activity 1/282 49/18639 0.0204081632653061 1.3488927485888 0.526680708253109 0.696307496994667 GO:0005008 hepatocyte growth factor receptor activity 1/282 49/18639 0.0204081632653061 1.3488927485888 0.526680708253109 0.696307496994667 GO:0005009 insulin receptor activity 1/282 49/18639 0.0204081632653061 1.3488927485888 0.526680708253109 0.696307496994667 GO:0005011 macrophage colony-stimulating factor receptor activity 1/282 49/18639 0.0204081632653061 1.3488927485888 0.526680708253109 0.696307496994667 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/282 49/18639 0.0204081632653061 1.3488927485888 0.526680708253109 0.696307496994667 GO:0005020 stem cell factor receptor activity 1/282 49/18639 0.0204081632653061 1.3488927485888 0.526680708253109 0.696307496994667 GO:0008288 boss receptor activity 1/282 49/18639 0.0204081632653061 1.3488927485888 0.526680708253109 0.696307496994667 GO:0016763 pentosyltransferase activity 1/282 49/18639 0.0204081632653061 1.3488927485888 0.526680708253109 0.696307496994667 GO:0036332 placental growth factor receptor activity 1/282 49/18639 0.0204081632653061 1.3488927485888 0.526680708253109 0.696307496994667 GO:0038062 protein tyrosine kinase collagen receptor activity 1/282 49/18639 0.0204081632653061 1.3488927485888 0.526680708253109 0.696307496994667 GO:0060175 brain-derived neurotrophic factor receptor activity 1/282 49/18639 0.0204081632653061 1.3488927485888 0.526680708253109 0.696307496994667 GO:0060590 ATPase regulator activity 1/282 49/18639 0.0204081632653061 1.3488927485888 0.526680708253109 0.696307496994667 GO:0005006 epidermal growth factor receptor activity 1/282 50/18639 0.02 1.32191489361702 0.533860699660996 0.698853081249139 GO:0005007 fibroblast growth factor receptor activity 1/282 50/18639 0.02 1.32191489361702 0.533860699660996 0.698853081249139 GO:0005017 platelet-derived growth factor receptor activity 1/282 50/18639 0.02 1.32191489361702 0.533860699660996 0.698853081249139 GO:0005019 platelet-derived growth factor beta-receptor activity 1/282 50/18639 0.02 1.32191489361702 0.533860699660996 0.698853081249139 GO:0032813 tumor necrosis factor receptor superfamily binding 1/282 50/18639 0.02 1.32191489361702 0.533860699660996 0.698853081249139 GO:0019887 protein kinase regulator activity 4/282 255/18639 0.0156862745098039 1.03679599499374 0.540820602412835 0.69984413045427 GO:0003743 translation initiation factor activity 1/282 51/18639 0.0196078431372549 1.29599499374218 0.540932154967661 0.69984413045427 GO:0005010 insulin-like growth factor receptor activity 1/282 51/18639 0.0196078431372549 1.29599499374218 0.540932154967661 0.69984413045427 GO:0005021 vascular endothelial growth factor receptor activity 1/282 51/18639 0.0196078431372549 1.29599499374218 0.540932154967661 0.69984413045427 GO:0005030 neurotrophin receptor activity 1/282 51/18639 0.0196078431372549 1.29599499374218 0.540932154967661 0.69984413045427 GO:0005048 signal sequence binding 1/282 51/18639 0.0196078431372549 1.29599499374218 0.540932154967661 0.69984413045427 GO:0003713 transcription coactivator activity 4/282 256/18639 0.015625 1.0327460106383 0.543912807546573 0.701354984196947 GO:0032182 ubiquitin-like protein binding 2/282 120/18639 0.0166666666666667 1.10159574468085 0.544380513800258 0.701354984196947 GO:0005080 protein kinase C binding 1/282 52/18639 0.0192307692307692 1.27107201309329 0.547896709104691 0.701354984196947 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/282 52/18639 0.0192307692307692 1.27107201309329 0.547896709104691 0.701354984196947 GO:0030159 signaling receptor complex adaptor activity 1/282 52/18639 0.0192307692307692 1.27107201309329 0.547896709104691 0.701354984196947 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/282 122/18639 0.0163934426229508 1.08353679804674 0.55333402479693 0.701354984196947 GO:0005003 ephrin receptor activity 1/282 53/18639 0.0188679245283019 1.24708952228021 0.554755972462548 0.701354984196947 GO:0005005 transmembrane-ephrin receptor activity 1/282 53/18639 0.0188679245283019 1.24708952228021 0.554755972462548 0.701354984196947 GO:0005246 calcium channel regulator activity 1/282 53/18639 0.0188679245283019 1.24708952228021 0.554755972462548 0.701354984196947 GO:0008146 sulfotransferase activity 1/282 53/18639 0.0188679245283019 1.24708952228021 0.554755972462548 0.701354984196947 GO:0017046 peptide hormone binding 1/282 53/18639 0.0188679245283019 1.24708952228021 0.554755972462548 0.701354984196947 GO:0038064 collagen receptor activity 1/282 53/18639 0.0188679245283019 1.24708952228021 0.554755972462548 0.701354984196947 GO:0015485 cholesterol binding 1/282 54/18639 0.0185185185185185 1.22399527186761 0.561511531257639 0.705869883338998 GO:0050661 NADP binding 1/282 54/18639 0.0185185185185185 1.22399527186761 0.561511531257639 0.705869883338998 GO:0140463 chromatin-protein adaptor activity 1/282 54/18639 0.0185185185185185 1.22399527186761 0.561511531257639 0.705869883338998 GO:0008236 serine-type peptidase activity 3/282 194/18639 0.0154639175257732 1.02209914454924 0.564863868116014 0.708744287353112 GO:0008374 O-acyltransferase activity 1/282 55/18639 0.0181818181818182 1.20174081237911 0.568164947893923 0.711543672974499 GO:0170055 lipid transmembrane transporter activity 1/282 56/18639 0.0178571428571429 1.1802811550152 0.574717761319123 0.717615427337207 GO:0019783 ubiquitin-like protein peptidase activity 2/282 127/18639 0.015748031496063 1.04087786898978 0.575171462813129 0.717615427337207 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/282 128/18639 0.015625 1.0327460106383 0.579444768575983 0.721593204312788 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/282 58/18639 0.0172413793103448 1.13958180484226 0.587527619146161 0.725327286492295 GO:0061980 regulatory RNA binding 1/282 58/18639 0.0172413793103448 1.13958180484226 0.587527619146161 0.725327286492295 GO:0016298 lipase activity 2/282 130/18639 0.0153846153846154 1.01685761047463 0.587896853262176 0.725327286492295 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/282 130/18639 0.0153846153846154 1.01685761047463 0.587896853262176 0.725327286492295 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/282 130/18639 0.0153846153846154 1.01685761047463 0.587896853262176 0.725327286492295 GO:0004879 nuclear receptor activity 1/282 59/18639 0.0169491525423729 1.12026685899748 0.593787627294312 0.731238466945773 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/282 132/18639 0.0151515151515152 1.00145067698259 0.596222753476975 0.732052694799955 GO:0008168 methyltransferase activity 3/282 204/18639 0.0147058823529412 0.971996245306633 0.598986749611602 0.732052694799955 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/282 60/18639 0.0166666666666667 1.10159574468085 0.599952960399963 0.732052694799955 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/282 60/18639 0.0166666666666667 1.10159574468085 0.599952960399963 0.732052694799955 GO:0098531 ligand-modulated transcription factor activity 1/282 60/18639 0.0166666666666667 1.10159574468085 0.599952960399963 0.732052694799955 GO:0015026 coreceptor activity 1/282 61/18639 0.0163934426229508 1.08353679804674 0.606025045289743 0.737153637814067 GO:0016887 ATP hydrolysis activity 6/282 417/18639 0.0143884892086331 0.951017909076994 0.606350435916232 0.737153637814067 GO:0015179 L-amino acid transmembrane transporter activity 1/282 62/18639 0.0161290322580645 1.06606039807824 0.612005287362533 0.741912081515108 GO:0140789 histone phosphatase activity 2/282 136/18639 0.0147058823529412 0.971996245306633 0.612495838724503 0.741912081515108 GO:0016922 nuclear receptor binding 2/282 137/18639 0.0145985401459854 0.964901382202205 0.616485276285237 0.745386743144877 GO:1901682 sulfur compound transmembrane transporter activity 1/282 63/18639 0.0158730158730159 1.04913880445795 0.617895070910133 0.745735430408781 GO:0140101 catalytic activity, acting on a tRNA 2/282 139/18639 0.0143884892086331 0.951017909076994 0.624369735466328 0.752184554502008 GO:0019843 rRNA binding 1/282 65/18639 0.0153846153846154 1.01685761047463 0.629408695952107 0.754156365420092 GO:0120013 lipid transfer activity 1/282 65/18639 0.0153846153846154 1.01685761047463 0.629408695952107 0.754156365420092 GO:0160215 deacylase activity 1/282 65/18639 0.0153846153846154 1.01685761047463 0.629408695952107 0.754156365420092 GO:0016741 transferase activity, transferring one-carbon groups 3/282 215/18639 0.013953488372093 0.922266204849085 0.63445106936276 0.758165907008745 GO:0008235 metalloexopeptidase activity 1/282 66/18639 0.0151515151515152 1.00145067698259 0.635035203314092 0.758165907008745 GO:0016500 protein-hormone receptor activity 1/282 67/18639 0.0149253731343284 0.986503651953001 0.640576584494592 0.762045489604479 GO:0042054 histone methyltransferase activity 1/282 67/18639 0.0149253731343284 0.986503651953001 0.640576584494592 0.762045489604479 GO:0019955 cytokine binding 2/282 144/18639 0.0138888888888889 0.917996453900709 0.643532219824223 0.764194511041265 GO:1990841 promoter-specific chromatin binding 1/282 68/18639 0.0147058823529412 0.971996245306633 0.646034122895008 0.765798024465561 GO:0016279 protein-lysine N-methyltransferase activity 1/282 69/18639 0.0144927536231884 0.95790934320074 0.651409082635658 0.770795444755716 GO:0015085 calcium ion transmembrane transporter activity 2/282 147/18639 0.0136054421768707 0.899261832392531 0.654655898468185 0.772933276781487 GO:0016278 lysine N-methyltransferase activity 1/282 70/18639 0.0142857142857143 0.944224924012158 0.656702708844422 0.772933276781487 GO:0016782 transferase activity, transferring sulphur-containing groups 1/282 70/18639 0.0142857142857143 0.944224924012158 0.656702708844422 0.772933276781487 GO:0046982 protein heterodimerization activity 5/282 369/18639 0.013550135501355 0.895606296488497 0.659480863442411 0.774831756518027 GO:0004521 RNA endonuclease activity 1/282 73/18639 0.0136986301369863 0.905421160011658 0.67210775861313 0.788274531706757 GO:0003774 cytoskeletal motor activity 2/282 153/18639 0.0130718954248366 0.863996662494785 0.676072317136935 0.791324442481157 GO:0031491 nucleosome binding 1/282 74/18639 0.0135135135135135 0.89318573893042 0.677088131987637 0.791324442481157 GO:0005506 iron ion binding 2/282 154/18639 0.012987012987013 0.858386294556507 0.679535140418784 0.792790997155248 GO:0044183 protein folding chaperone 1/282 75/18639 0.0133333333333333 0.881276595744681 0.681993122387825 0.794265195075137 GO:0051536 iron-sulfur cluster binding 1/282 76/18639 0.0131578947368421 0.86968085106383 0.686823866811798 0.798492782220009 GO:0051540 metal cluster binding 1/282 77/18639 0.012987012987013 0.858386294556507 0.691581485168694 0.802620746312708 GO:0022804 active transmembrane transporter activity 6/282 457/18639 0.0131291028446389 0.867777829507891 0.69321522219418 0.803115196444477 GO:0019199 transmembrane receptor protein kinase activity 1/282 78/18639 0.0128205128205128 0.847381342062193 0.696267080534626 0.805248014879176 GO:0000049 tRNA binding 1/282 80/18639 0.0125 0.826196808510638 0.705426531941857 0.805606093219575 GO:0008083 growth factor activity 2/282 162/18639 0.0123456790123457 0.815996847911741 0.70616205468042 0.805606093219575 GO:0015101 organic cation transmembrane transporter activity 1/282 81/18639 0.0123456790123457 0.815996847911741 0.709902512220558 0.805606093219575 GO:0033192 calmodulin-dependent protein phosphatase activity 1/282 81/18639 0.0123456790123457 0.815996847911741 0.709902512220558 0.805606093219575 GO:0140791 histone H2AXS140 phosphatase activity 1/282 81/18639 0.0123456790123457 0.815996847911741 0.709902512220558 0.805606093219575 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/282 81/18639 0.0123456790123457 0.815996847911741 0.709902512220558 0.805606093219575 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/282 81/18639 0.0123456790123457 0.815996847911741 0.709902512220558 0.805606093219575 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/282 81/18639 0.0123456790123457 0.815996847911741 0.709902512220558 0.805606093219575 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/282 81/18639 0.0123456790123457 0.815996847911741 0.709902512220558 0.805606093219575 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/282 81/18639 0.0123456790123457 0.815996847911741 0.709902512220558 0.805606093219575 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/282 81/18639 0.0123456790123457 0.815996847911741 0.709902512220558 0.805606093219575 GO:0005539 glycosaminoglycan binding 3/282 242/18639 0.012396694214876 0.81936873571303 0.712010965744565 0.80647984343245 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/282 82/18639 0.0121951219512195 0.806045666839647 0.714310718468742 0.80647984343245 GO:0033549 MAP kinase phosphatase activity 1/282 82/18639 0.0121951219512195 0.806045666839647 0.714310718468742 0.80647984343245 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/282 83/18639 0.0120481927710843 0.796334273263266 0.71865217330475 0.808635694158476 GO:0008135 translation factor activity, RNA binding 1/282 83/18639 0.0120481927710843 0.796334273263266 0.71865217330475 0.808635694158476 GO:0004860 protein kinase inhibitor activity 1/282 84/18639 0.0119047619047619 0.786854103343465 0.722927883971277 0.80933845596111 GO:0017018 myosin phosphatase activity 1/282 84/18639 0.0119047619047619 0.786854103343465 0.722927883971277 0.80933845596111 GO:0180051 translation factor activity 1/282 84/18639 0.0119047619047619 0.786854103343465 0.722927883971277 0.80933845596111 GO:0008081 phosphoric diester hydrolase activity 1/282 87/18639 0.0114942528735632 0.759721203228173 0.735370397559825 0.821884561978628 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/282 88/18639 0.0113636363636364 0.751088007736944 0.73939290445332 0.824993760841372 GO:0003727 single-stranded RNA binding 1/282 89/18639 0.0112359550561798 0.742648816638776 0.743354480699569 0.8252599827466 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/282 89/18639 0.0112359550561798 0.742648816638776 0.743354480699569 0.8252599827466 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/282 89/18639 0.0112359550561798 0.742648816638776 0.743354480699569 0.8252599827466 GO:0004721 phosphoprotein phosphatase activity 2/282 175/18639 0.0114285714285714 0.755379939209726 0.745487691634959 0.826248858228747 GO:0140793 histone H2AXY142 phosphatase activity 1/282 90/18639 0.0111111111111111 0.734397163120567 0.747256046006455 0.826630540897094 GO:0004252 serine-type endopeptidase activity 2/282 176/18639 0.0113636363636364 0.751088007736944 0.748318173864738 0.826630540897094 GO:0004867 serine-type endopeptidase inhibitor activity 1/282 95/18639 0.0105263157894737 0.695744680851064 0.765894941402559 0.844643675012772 GO:0004896 cytokine receptor activity 1/282 96/18639 0.0104166666666667 0.688497340425532 0.769454994601679 0.846368248318927 GO:0008237 metallopeptidase activity 2/282 184/18639 0.0108695652173913 0.718432007400555 0.770004195839024 0.846368248318927 GO:0030594 neurotransmitter receptor activity 1/282 97/18639 0.0103092783505155 0.681399429699496 0.772961098874036 0.848216387378274 GO:0004725 protein tyrosine phosphatase activity 1/282 98/18639 0.0102040816326531 0.674446374294399 0.776414068894397 0.849202887853247 GO:0005249 voltage-gated potassium channel activity 1/282 98/18639 0.0102040816326531 0.674446374294399 0.776414068894397 0.849202887853247 GO:0061630 ubiquitin protein ligase activity 4/282 353/18639 0.0113314447592068 0.7489602796697 0.784468989581786 0.856604069083559 GO:0015171 amino acid transmembrane transporter activity 1/282 102/18639 0.00980392156862745 0.647997496871089 0.789710474726916 0.8609138781859 GO:0004722 protein serine/threonine phosphatase activity 1/282 103/18639 0.00970873786407767 0.641706259037389 0.792909570919774 0.862986685207283 GO:0016829 lyase activity 2/282 200/18639 0.01 0.660957446808511 0.808542875382996 0.878563745309955 GO:0004620 phospholipase activity 1/282 109/18639 0.00917431192660551 0.606382978723404 0.8111109640991 0.879916461869334 GO:0004222 metalloendopeptidase activity 1/282 110/18639 0.00909090909090909 0.600870406189555 0.813985584073415 0.88159676450948 GO:0061659 ubiquitin-like protein ligase activity 4/282 372/18639 0.010752688172043 0.710706932052162 0.817356786594375 0.883808557862211 GO:0004540 RNA nuclease activity 1/282 121/18639 0.00826446280991736 0.546245823808686 0.842869290866063 0.909545834890927 GO:0008528 G protein-coupled peptide receptor activity 1/282 122/18639 0.00819672131147541 0.541768399023369 0.845262144304651 0.909545834890927 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/282 122/18639 0.00819672131147541 0.541768399023369 0.845262144304651 0.909545834890927 GO:0005267 potassium channel activity 1/282 124/18639 0.00806451612903226 0.533030199039122 0.849939463888981 0.913101362659406 GO:0004519 endonuclease activity 1/282 127/18639 0.0078740157480315 0.52043893449489 0.856692588371656 0.917392224262724 GO:0042826 histone deacetylase binding 1/282 127/18639 0.0078740157480315 0.52043893449489 0.856692588371656 0.917392224262724 GO:0001653 peptide receptor activity 1/282 128/18639 0.0078125 0.516373005319149 0.858875642070835 0.918251289352259 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/282 229/18639 0.00873362445414847 0.577255412059835 0.863993335492242 0.920602555951639 GO:0005262 calcium channel activity 1/282 131/18639 0.00763358778625954 0.504547669319474 0.865227966119961 0.920602555951639 GO:0031072 heat shock protein binding 1/282 131/18639 0.00763358778625954 0.504547669319474 0.865227966119961 0.920602555951639 GO:0005179 hormone activity 1/282 132/18639 0.00757575757575758 0.500725338491296 0.867281441025633 0.921313351888252 GO:0051087 protein-folding chaperone binding 1/282 134/18639 0.00746268656716418 0.493251825976501 0.871295326115318 0.923236386847419 GO:0003712 transcription coregulator activity 5/282 495/18639 0.0101010101010101 0.667633784655061 0.872487913234891 0.923236386847419 GO:0015297 antiporter activity 1/282 135/18639 0.00740740740740741 0.489598108747045 0.87325667267222 0.923236386847419 GO:0099094 ligand-gated monoatomic cation channel activity 1/282 136/18639 0.00735294117647059 0.485998122653317 0.875188234405166 0.923809802983231 GO:0070851 growth factor receptor binding 1/282 139/18639 0.00719424460431655 0.475508954538497 0.880808684021475 0.926800276699812 GO:0140767 enzyme-substrate adaptor activity 1/282 139/18639 0.00719424460431655 0.475508954538497 0.880808684021475 0.926800276699812 GO:0020037 heme binding 1/282 142/18639 0.00704225352112676 0.465462990710219 0.886176893966848 0.930975725889342 GO:0022843 voltage-gated monoatomic cation channel activity 1/282 143/18639 0.00699300699300699 0.462208004761196 0.887912208661195 0.931327474384377 GO:0042393 histone binding 2/282 247/18639 0.00809716599190283 0.53518821603928 0.890593181926584 0.932668450364061 GO:0005261 monoatomic cation channel activity 3/282 341/18639 0.00879765395894428 0.58148748986086 0.892165253960632 0.932845745100347 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 3/282 349/18639 0.00859598853868195 0.568158263732244 0.900985635985393 0.940579258911388 GO:0046906 tetrapyrrole binding 1/282 152/18639 0.00657894736842105 0.434840425531915 0.902390326594685 0.940579258911388 GO:0003730 mRNA 3'-UTR binding 2/282 262/18639 0.00763358778625954 0.504547669319474 0.908991903472557 0.945977489529344 GO:0015079 potassium ion transmembrane transporter activity 1/282 160/18639 0.00625 0.413098404255319 0.913686922000452 0.949377817391094 GO:0008201 heparin binding 1/282 172/18639 0.00581395348837209 0.384277585353785 0.928235690336177 0.961847679011494 GO:0005244 voltage-gated monoatomic ion channel activity 1/282 173/18639 0.00578034682080925 0.382056327634977 0.929331565969751 0.961847679011494 GO:0003823 antigen binding 1/282 174/18639 0.00574712643678161 0.379860601614087 0.930410765493011 0.961847679011494 GO:0022832 voltage-gated channel activity 1/282 175/18639 0.00571428571428571 0.377689969604863 0.931473541779552 0.961847679011494 GO:0043021 ribonucleoprotein complex binding 1/282 177/18639 0.00564971751412429 0.373422286332492 0.933550817089164 0.962115449006843 GO:0140098 catalytic activity, acting on RNA 3/282 387/18639 0.00775193798449612 0.512370113805047 0.934626436178076 0.962115449006843 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 4/282 484/18639 0.00826446280991736 0.546245823808686 0.937397805446364 0.963476878859092 GO:0001216 DNA-binding transcription activator activity 4/282 491/18639 0.00814663951120163 0.538458205139316 0.941719908452366 0.963598086474925 GO:0015276 ligand-gated monoatomic ion channel activity 1/282 186/18639 0.00537634408602151 0.355353466026081 0.942148756926195 0.963598086474925 GO:0022834 ligand-gated channel activity 1/282 188/18639 0.00531914893617021 0.351573110004527 0.943903466690876 0.963598086474925 GO:0046943 carboxylic acid transmembrane transporter activity 1/282 188/18639 0.00531914893617021 0.351573110004527 0.943903466690876 0.963598086474925 GO:0005342 organic acid transmembrane transporter activity 1/282 189/18639 0.00529100529100529 0.349712934819318 0.944760830649099 0.963598086474925 GO:0003714 transcription corepressor activity 1/282 204/18639 0.00490196078431373 0.323998748435544 0.956160053425681 0.973731141696903 GO:0004518 nuclease activity 1/282 209/18639 0.00478468899521531 0.316247582205029 0.959412464218581 0.974690499759751 GO:0008094 ATP-dependent activity, acting on DNA 1/282 210/18639 0.00476190476190476 0.314741641337386 0.960033499763364 0.974690499759751 GO:0005216 monoatomic ion channel activity 3/282 448/18639 0.00669642857142857 0.442605433130699 0.967407090857335 0.979948704239802 GO:0046873 metal ion transmembrane transporter activity 3/282 450/18639 0.00666666666666667 0.44063829787234 0.968159847647444 0.979948704239802 GO:0045182 translation regulator activity 2/282 356/18639 0.00561797752808989 0.371324408319388 0.972580712185743 0.982927315506868 GO:0140104 molecular carrier activity 1/282 249/18639 0.00401606425702811 0.265444757754422 0.978110084896082 0.987015487793467 GO:0140297 DNA-binding transcription factor binding 3/282 488/18639 0.00614754098360656 0.406326299267527 0.979694749205637 0.987116679123861 GO:0008514 organic anion transmembrane transporter activity 1/282 269/18639 0.00371747211895911 0.245709088032904 0.983932463985491 0.989822294683116 GO:1901681 sulfur compound binding 1/282 275/18639 0.00363636363636364 0.240348162475822 0.985356930947703 0.989822294683116 GO:0015291 secondary active transmembrane transporter activity 1/282 287/18639 0.00348432055749129 0.230298761954185 0.987839318123298 0.990819225568617 GO:0022836 gated channel activity 1/282 318/18639 0.00314465408805031 0.207848253713368 0.992478519772998 0.993973216338922 GO:0140097 catalytic activity, acting on DNA 1/282 336/18639 0.00297619047619048 0.196713525835866 0.994311658078188 0.994311658078188