ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	90/3458	175/18639	0.514285714285714	2.77205651491366	7.19427158501205e-23	9.60435256599109e-20
GO:0016874	ligase activity	60/3458	167/18639	0.359281437125749	1.93656642758439	7.72997768212698e-08	5.15976010281976e-05
GO:0004812	aminoacyl-tRNA ligase activity	22/3458	41/18639	0.536585365853659	2.89225408737604	4.71272815661063e-07	0.000142761995935188
GO:0016875	ligase activity, forming carbon-oxygen bonds	22/3458	41/18639	0.536585365853659	2.89225408737604	4.71272815661063e-07	0.000142761995935188
GO:0140375	immune receptor activity	55/3458	156/18639	0.352564102564103	1.90035925612849	5.34689123352762e-07	0.000142761995935188
GO:0061650	ubiquitin-like protein conjugating enzyme activity	21/3458	41/18639	0.51219512195122	2.76078799249531	2.33860550454541e-06	0.000520339724761353
GO:0140101	catalytic activity, acting on a tRNA	48/3458	139/18639	0.345323741007194	1.86133291169262	5.31526560043139e-06	0.00101369708236799
GO:0051020	GTPase binding	90/3458	315/18639	0.285714285714286	1.54003139717425	8.2374978188869e-06	0.00137463244852675
GO:0003925	G protein activity	24/3458	54/18639	0.444444444444444	2.3956043956044	1.08406331963323e-05	0.00160802725745595
GO:0019210	kinase inhibitor activity	34/3458	90/18639	0.377777777777778	2.03626373626374	1.42223668297777e-05	0.00189868597177532
GO:0015078	proton transmembrane transporter activity	58/3458	185/18639	0.313513513513514	1.68987228987229	1.79478532026289e-05	0.00192911486123787
GO:0106310	protein serine kinase activity	99/3458	361/18639	0.274238227146814	1.47817418039025	1.96005717038129e-05	0.00192911486123787
GO:0004860	protein kinase inhibitor activity	32/3458	84/18639	0.380952380952381	2.05337519623234	2.06448459705703e-05	0.00192911486123787
GO:0031267	small GTPase binding	81/3458	283/18639	0.286219081272085	1.54275230070283	2.12416660873717e-05	0.00192911486123787
GO:0003924	GTPase activity	92/3458	331/18639	0.277945619335347	1.49815743169218	2.16754478790772e-05	0.00192911486123787
GO:0004896	cytokine receptor activity	35/3458	96/18639	0.364583333333333	1.96514423076923	2.61152320869761e-05	0.00209067681679207
GO:0031625	ubiquitin protein ligase binding	85/3458	302/18639	0.281456953642384	1.51708390946802	2.66228508505357e-05	0.00209067681679207
GO:0005085	guanyl-nucleotide exchange factor activity	68/3458	230/18639	0.295652173913043	1.59359770664119	3.09423824945434e-05	0.0022948933683453
GO:0004674	protein serine/threonine kinase activity	114/3458	433/18639	0.263279445727483	1.41910514427835	3.4554051858745e-05	0.00233405901798747
GO:0019207	kinase regulator activity	81/3458	287/18639	0.282229965156794	1.52125052647701	3.66285764347457e-05	0.00233405901798747
GO:0044389	ubiquitin-like protein ligase binding	89/3458	322/18639	0.27639751552795	1.48981298204901	3.67155351144096e-05	0.00233405901798747
GO:0035591	signaling adaptor activity	43/3458	129/18639	0.333333333333333	1.7967032967033	4.24177540208537e-05	0.00257398643717453
GO:0061631	ubiquitin conjugating enzyme activity	17/3458	35/18639	0.485714285714286	2.61805337519623	5.20048676066103e-05	0.0030120225523068
GO:0045296	cadherin binding	91/3458	334/18639	0.272455089820359	1.4685628742515	5.41487200414705e-05	0.0030120225523068
GO:0019902	phosphatase binding	57/3458	190/18639	0.3	1.61703296703297	8.39720821418262e-05	0.00448410918637352
GO:0030695	GTPase regulator activity	124/3458	489/18639	0.253578732106339	1.36681723184791	9.76329322795142e-05	0.00501307556127506
GO:0016504	peptidase activator activity	23/3458	57/18639	0.403508771929825	2.17495662232504	0.00010468077448905	0.00511226684751284
GO:0060589	nucleoside-triphosphatase regulator activity	124/3458	490/18639	0.253061224489796	1.36402780892577	0.000107223574329857	0.00511226684751284
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	10/3458	16/18639	0.625	3.36881868131868	0.000127379876720331	0.0058638667386773
GO:0003953	NAD+ nucleosidase activity	8/3458	11/18639	0.727272727272727	3.92007992007992	0.000134321588287149	0.00597731067877813
GO:0140996	histone H3 kinase activity	94/3458	357/18639	0.263305322128852	1.41924462092529	0.00016072026221175	0.00692134032428022
GO:0043130	ubiquitin binding	34/3458	100/18639	0.34	1.83263736263736	0.000167460037164671	0.00698622342546364
GO:0009055	electron transfer activity	38/3458	116/18639	0.327586206896552	1.76572565365669	0.000173380469059479	0.0070140280664971
GO:0141003	histone H2AX kinase activity	93/3458	354/18639	0.26271186440678	1.41604581858819	0.000189117546010179	0.00742564482128203
GO:0035173	histone kinase activity	94/3458	360/18639	0.261111111111111	1.40741758241758	0.000220954399541353	0.00842783209679161
GO:0004857	enzyme inhibitor activity	106/3458	416/18639	0.254807692307692	1.37344146238377	0.000249084846095049	0.00923689637602475
GO:0019003	GDP binding	27/3458	75/18639	0.36	1.94043956043956	0.000266856954863582	0.0096284874254833
GO:0016505	peptidase activator activity involved in apoptotic process	11/3458	20/18639	0.55	2.96456043956044	0.000281948252415064	0.0098996540403903
GO:0019887	protein kinase regulator activity	70/3458	255/18639	0.274509803921569	1.47963800904977	0.000293003008217	0.0098996540403903
GO:0043021	ribonucleoprotein complex binding	52/3458	177/18639	0.293785310734463	1.58353510895884	0.000296618847652144	0.0098996540403903
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	25/3458	68/18639	0.367647058823529	1.98165804783452	0.000306197606482247	0.00997009279643413
GO:0019903	protein phosphatase binding	44/3458	144/18639	0.305555555555556	1.64697802197802	0.000329612214855781	0.0104769596864873
GO:0005525	GTP binding	97/3458	378/18639	0.256613756613757	1.38317634746206	0.00034298115576941	0.0105863848149236
GO:0000287	magnesium ion binding	64/3458	230/18639	0.278260869565217	1.49985666507406	0.000348914555697858	0.0105863848149236
GO:0016922	nuclear receptor binding	42/3458	137/18639	0.306569343065693	1.65244244806289	0.000411594542131281	0.012210638083228
GO:0050700	CARD domain binding	9/3458	15/18639	0.6	3.23406593406593	0.000435585729125776	0.0126414553996285
GO:0003743	translation initiation factor activity	20/3458	51/18639	0.392156862745098	2.11376858435682	0.00045404210220616	0.0128967277967069
GO:0048027	mRNA 5'-UTR binding	12/3458	24/18639	0.5	2.69505494505495	0.000476197776491591	0.0129209056458077
GO:0019001	guanyl nucleotide binding	101/3458	400/18639	0.2525	1.36100274725275	0.000484544346321686	0.0129209056458077
GO:0032561	guanyl ribonucleotide binding	101/3458	400/18639	0.2525	1.36100274725275	0.000484544346321686	0.0129209056458077
GO:0140857	histone H3T45 kinase activity	67/3458	246/18639	0.272357723577236	1.46803805950147	0.000493607631412878	0.0129209056458077
GO:0035403	histone H3T6 kinase activity	67/3458	247/18639	0.271255060728745	1.46209458557637	0.000556596158780337	0.0135973317105716
GO:0004679	AMP-activated protein kinase activity	67/3458	248/18639	0.270161290322581	1.45619904289259	0.000626704725098711	0.0135973317105716
GO:0140297	DNA-binding transcription factor binding	119/3458	488/18639	0.243852459016393	1.31439155107188	0.000689337372801895	0.0135973317105716
GO:0044325	transmembrane transporter binding	41/3458	136/18639	0.301470588235294	1.62495959922431	0.000698068624963808	0.0135973317105716
GO:0008135	translation factor activity, RNA binding	28/3458	83/18639	0.337349397590361	1.81835032437442	0.000698985210359948	0.0135973317105716
GO:0004676	3-phosphoinositide-dependent protein kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0004711	ribosomal protein S6 kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0035175	histone H3S10 kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0035979	histone H2AXS139 kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0044022	histone H3S28 kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0044023	histone H4S1 kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0044024	histone H2AS1 kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0044025	histone H2BS14 kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0072354	histone H3T3 kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0072371	histone H2AS121 kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0072518	Rho-dependent protein serine/threonine kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0140823	histone H2BS36 kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0140855	histone H3S57 kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0140995	histone H2A kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0140997	histone H4 kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0140998	histone H2B kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:1990244	histone H2AT120 kinase activity	66/3458	245/18639	0.269387755102041	1.45202960305001	0.000743524505521892	0.0135973317105716
GO:0003712	transcription coregulator activity	120/3458	495/18639	0.242424242424242	1.30669330669331	0.000828704649695683	0.0144797340876373
GO:0004708	MAP kinase kinase activity	9/3458	16/18639	0.5625	3.03193681318681	0.000831850396504204	0.0144797340876373
GO:0008142	oxysterol binding	9/3458	16/18639	0.5625	3.03193681318681	0.000831850396504204	0.0144797340876373
GO:0004677	DNA-dependent protein kinase activity	66/3458	246/18639	0.268292682926829	1.44612704368802	0.000835160692695187	0.0144797340876373
GO:0180051	translation factor activity	28/3458	84/18639	0.333333333333333	1.7967032967033	0.000865445984311568	0.0148124408853326
GO:0033218	amide binding	66/3458	247/18639	0.267206477732794	1.44027227832896	0.000936736710586803	0.0156317938579173
GO:0035402	histone H3T11 kinase activity	66/3458	247/18639	0.267206477732794	1.44027227832896	0.000936736710586803	0.0156317938579173
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	65/3458	243/18639	0.267489711934156	1.44179894179894	0.000989284247448728	0.0163048700042476
GO:0015631	tubulin binding	96/3458	385/18639	0.249350649350649	1.34402740117026	0.00102022074920598	0.0166096914657315
GO:0055106	ubiquitin-protein transferase regulator activity	15/3458	36/18639	0.416666666666667	2.24587912087912	0.00110233887676477	0.0177303903672406
GO:0050786	RAGE receptor binding	7/3458	11/18639	0.636363636363636	3.43006993006993	0.00122906595700735	0.0190791052628466
GO:0070990	snRNP binding	7/3458	11/18639	0.636363636363636	3.43006993006993	0.00122906595700735	0.0190791052628466
GO:1990948	ubiquitin ligase inhibitor activity	7/3458	11/18639	0.636363636363636	3.43006993006993	0.00122906595700735	0.0190791052628466
GO:0019955	cytokine binding	42/3458	144/18639	0.291666666666667	1.57211538461538	0.00125681677295317	0.0192856366884193
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	16/3458	40/18639	0.4	2.15604395604396	0.00128527120996955	0.0194981484694245
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	9/3458	17/18639	0.529411764705882	2.85358758888171	0.00147760243031189	0.0221640364546783
GO:0032182	ubiquitin-like protein binding	36/3458	120/18639	0.3	1.61703296703297	0.00157232009169903	0.023322748026869
GO:1901981	phosphatidylinositol phosphate binding	51/3458	185/18639	0.275675675675676	1.48592218592219	0.00163775152781827	0.0239738831014053
GO:0035091	phosphatidylinositol binding	73/3458	284/18639	0.257042253521127	1.38548599288036	0.00165213276803692	0.0239738831014053
GO:0000049	tRNA binding	26/3458	80/18639	0.325	1.75178571428571	0.00196193992667985	0.0280808517044278
GO:0005543	phospholipid binding	118/3458	497/18639	0.237424547283702	1.27974440046875	0.00199368663885408	0.0280808517044278
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	11/3458	24/18639	0.458333333333333	2.47046703296703	0.00201929720121728	0.0280808517044278
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	11/3458	24/18639	0.458333333333333	2.47046703296703	0.00201929720121728	0.0280808517044278
GO:0016411	acylglycerol O-acyltransferase activity	13/3458	31/18639	0.419354838709677	2.26036866359447	0.00218082533927543	0.0300144518343577
GO:0022853	active monoatomic ion transmembrane transporter activity	35/3458	118/18639	0.296610169491525	1.59876140808344	0.00224120059664663	0.0305306407808495
GO:0031492	nucleosomal DNA binding	16/3458	42/18639	0.380952380952381	2.05337519623234	0.00234506771823712	0.031622882867137
GO:0019843	rRNA binding	22/3458	65/18639	0.338461538461538	1.82434488588335	0.0023870420053342	0.0318670107712116
GO:0035259	nuclear glucocorticoid receptor binding	7/3458	12/18639	0.583333333333333	3.14423076923077	0.00247777271015815	0.0327507580996151
GO:0002020	protease binding	39/3458	136/18639	0.286764705882353	1.54569327731092	0.0025654318426136	0.033050566464709
GO:0046625	sphingolipid binding	12/3458	28/18639	0.428571428571429	2.31004709576138	0.0025725300277938	0.033050566464709
GO:0055105	ubiquitin-protein transferase inhibitor activity	8/3458	15/18639	0.533333333333333	2.87472527472527	0.00257472577702602	0.033050566464709
GO:0019787	ubiquitin-like protein transferase activity	113/3458	479/18639	0.235908141962422	1.2715708091491	0.00305445249236137	0.0388351816885946
GO:0051861	glycolipid binding	12/3458	29/18639	0.413793103448276	2.23039029935582	0.00365631154112382	0.0457490597585808
GO:0016755	aminoacyltransferase activity	116/3458	496/18639	0.233870967741935	1.26059021623538	0.00366677857241059	0.0457490597585808
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	37/3458	130/18639	0.284615384615385	1.53410819949281	0.00373500424171424	0.0460047756363272
GO:0061791	GTPase motor activity	15/3458	40/18639	0.375	2.02129120879121	0.00379065567040899	0.0460047756363272
GO:1990606	membrane scission GTPase motor activity	15/3458	40/18639	0.375	2.02129120879121	0.00379065567040899	0.0460047756363272
GO:0097001	ceramide binding	9/3458	19/18639	0.473684210526316	2.55320994794679	0.00392901522640493	0.0472543723175729
GO:0003954	NADH dehydrogenase activity	16/3458	44/18639	0.363636363636364	1.96003996003996	0.00404610623025384	0.0479218252166405
GO:0016651	oxidoreductase activity, acting on NAD(P)H	27/3458	88/18639	0.306818181818182	1.65378371628372	0.00405630430672688	0.0479218252166405
GO:0071889	14-3-3 protein binding	13/3458	33/18639	0.393939393939394	2.12337662337662	0.00419825795982457	0.0489724645832401
GO:0038187	pattern recognition receptor activity	17/3458	48/18639	0.354166666666667	1.90899725274725	0.00423604435937926	0.0489724645832401
GO:0004862	cAMP-dependent protein kinase inhibitor activity	6/3458	10/18639	0.6	3.23406593406593	0.0042919688061716	0.0489724645832401
GO:0035256	G protein-coupled glutamate receptor binding	6/3458	10/18639	0.6	3.23406593406593	0.0042919688061716	0.0489724645832401
GO:0004112	cyclic-nucleotide phosphodiesterase activity	11/3458	26/18639	0.423076923076923	2.28043110735418	0.00434885128380033	0.0492009869819783
GO:0061134	peptidase regulator activity	58/3458	226/18639	0.256637168141593	1.38330253816979	0.0048148703526669	0.0540155623597505
GO:0008137	NADH dehydrogenase (ubiquinone) activity	15/3458	41/18639	0.365853658536585	1.97199142321094	0.00496849836508716	0.0552745443115946
GO:0001965	G-protein alpha-subunit binding	12/3458	30/18639	0.4	2.15604395604396	0.00507908132790502	0.0555784719078131
GO:0051721	protein phosphatase 2A binding	12/3458	30/18639	0.4	2.15604395604396	0.00507908132790502	0.0555784719078131
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	10/3458	23/18639	0.434782608695652	2.34352603917821	0.00513055799028135	0.0556853245286634
GO:0005201	extracellular matrix structural constituent	45/3458	168/18639	0.267857142857143	1.44377943485086	0.00530501195178299	0.0571144431905669
GO:0001222	transcription corepressor binding	17/3458	49/18639	0.346938775510204	1.87003812514017	0.00538463339633943	0.0575078846729051
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	84/3458	349/18639	0.240687679083095	1.29733303945338	0.00561138457369545	0.0594539556022494
GO:0030291	protein serine/threonine kinase inhibitor activity	16/3458	46/18639	0.347826086956522	1.87482083134257	0.00664406970550332	0.0698412051720231
GO:0008017	microtubule binding	68/3458	276/18639	0.246376811594203	1.32799808886765	0.00680557218265025	0.0702625336024078
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	19/3458	58/18639	0.327586206896552	1.76572565365669	0.00682916947756309	0.0702625336024078
GO:0070402	NADPH binding	8/3458	17/18639	0.470588235294118	2.53652230122818	0.00684204447064645	0.0702625336024078
GO:0033293	monocarboxylic acid binding	24/3458	79/18639	0.30379746835443	1.63750173876756	0.00743346630190641	0.0757532634583592
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	7/3458	14/18639	0.5	2.69505494505495	0.00759113626084146	0.0767739917289648
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	14/3458	39/18639	0.358974358974359	1.93491124260355	0.00792519474732756	0.0795498871254307
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	9/3458	21/18639	0.428571428571429	2.31004709576138	0.00876579559987364	0.0866839787098616
GO:0051010	microtubule plus-end binding	9/3458	21/18639	0.428571428571429	2.31004709576138	0.00876579559987364	0.0866839787098616
GO:0017022	myosin binding	23/3458	76/18639	0.302631578947368	1.63121746674378	0.00910346767297323	0.0888581662780385
GO:0051219	phosphoprotein binding	27/3458	93/18639	0.290322580645161	1.56487061325771	0.00911877811242792	0.0888581662780385
GO:0001221	transcription coregulator binding	32/3458	115/18639	0.278260869565217	1.49985666507406	0.00949385859508148	0.0918427624958969
GO:0005484	SNAP receptor activity	13/3458	36/18639	0.361111111111111	1.94642857142857	0.0097839675846703	0.0939683217664377
GO:0001098	basal transcription machinery binding	19/3458	60/18639	0.316666666666667	1.70686813186813	0.0101480887220269	0.0960440035081022
GO:0001099	basal RNA polymerase II transcription machinery binding	19/3458	60/18639	0.316666666666667	1.70686813186813	0.0101480887220269	0.0960440035081022
GO:0004709	MAP kinase kinase kinase activity	10/3458	25/18639	0.4	2.15604395604396	0.0102499972830485	0.0960440035081022
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	8/3458	18/18639	0.444444444444444	2.3956043956044	0.0103385245323351	0.0960440035081022
GO:0030020	extracellular matrix structural constituent conferring tensile strength	15/3458	44/18639	0.340909090909091	1.83753746253746	0.010359802625593	0.0960440035081022
GO:0019888	protein phosphatase regulator activity	30/3458	107/18639	0.280373831775701	1.51124576358221	0.0105255083136258	0.0969072661978652
GO:0004129	cytochrome-c oxidase activity	7/3458	15/18639	0.466666666666667	2.51538461538462	0.01198049543418	0.108067306788042
GO:0031386	protein tag activity	7/3458	15/18639	0.466666666666667	2.51538461538462	0.01198049543418	0.108067306788042
GO:0141047	molecular tag activity	7/3458	15/18639	0.466666666666667	2.51538461538462	0.01198049543418	0.108067306788042
GO:0019956	chemokine binding	12/3458	33/18639	0.363636363636364	1.96003996003996	0.0120917240504272	0.108338601391412
GO:0019208	phosphatase regulator activity	32/3458	117/18639	0.273504273504274	1.47421808960271	0.0123215928606552	0.108935936880627
GO:1990782	protein tyrosine kinase binding	32/3458	117/18639	0.273504273504274	1.47421808960271	0.0123215928606552	0.108935936880627
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	14/3458	41/18639	0.341463414634146	1.84052532833021	0.0128389595810694	0.112763230531103
GO:0008603	cAMP-dependent protein kinase regulator activity	6/3458	12/18639	0.5	2.69505494505495	0.0134571317401793	0.116657603072333
GO:0042301	phosphate ion binding	6/3458	12/18639	0.5	2.69505494505495	0.0134571317401793	0.116657603072333
GO:0004842	ubiquitin-protein transferase activity	102/3458	449/18639	0.2271714922049	1.22447930688465	0.014172388588401	0.122065411390421
GO:0046332	SMAD binding	23/3458	79/18639	0.291139240506329	1.56927249965225	0.0147721865745128	0.126415827416504
GO:0005520	insulin-like growth factor binding	8/3458	19/18639	0.421052631578947	2.26951995373048	0.0149999858457387	0.127547650344339
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	17/3458	54/18639	0.314814814814815	1.69688644688645	0.0154621880728366	0.130645703020487
GO:0004602	glutathione peroxidase activity	9/3458	23/18639	0.391304347826087	2.10917343526039	0.017125593994344	0.141127580138575
GO:0042171	lysophosphatidic acid acyltransferase activity	9/3458	23/18639	0.391304347826087	2.10917343526039	0.017125593994344	0.141127580138575
GO:0043274	phospholipase binding	9/3458	23/18639	0.391304347826087	2.10917343526039	0.017125593994344	0.141127580138575
GO:0071617	lysophospholipid acyltransferase activity	9/3458	23/18639	0.391304347826087	2.10917343526039	0.017125593994344	0.141127580138575
GO:0003779	actin binding	100/3458	443/18639	0.225733634311512	1.21672909483293	0.0177899403828544	0.14515515128404
GO:0016675	oxidoreductase activity, acting on a heme group of donors	7/3458	16/18639	0.4375	2.35817307692308	0.017940524316005	0.14515515128404
GO:0043023	ribosomal large subunit binding	7/3458	16/18639	0.4375	2.35817307692308	0.017940524316005	0.14515515128404
GO:0043177	organic acid binding	47/3458	189/18639	0.248677248677249	1.34039769754055	0.0182659810733288	0.146898100800566
GO:0004683	calcium/calmodulin-dependent protein kinase activity	10/3458	27/18639	0.37037037037037	1.996336996337	0.0185340740634131	0.148161610027884
GO:0043022	ribosome binding	30/3458	112/18639	0.267857142857143	1.44377943485086	0.0200162445839226	0.158570885915893
GO:0030246	carbohydrate binding	66/3458	280/18639	0.235714285714286	1.27052590266876	0.0200737675803639	0.158570885915893
GO:0030742	GTP-dependent protein binding	8/3458	20/18639	0.4	2.15604395604396	0.0210131123869236	0.163008626780733
GO:0031994	insulin-like growth factor I binding	6/3458	13/18639	0.461538461538462	2.48774302620456	0.0211239643693384	0.163008626780733
GO:0035325	Toll-like receptor binding	6/3458	13/18639	0.461538461538462	2.48774302620456	0.0211239643693384	0.163008626780733
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	6/3458	13/18639	0.461538461538462	2.48774302620456	0.0211239643693384	0.163008626780733
GO:0016209	antioxidant activity	24/3458	86/18639	0.27906976744186	1.50421671351904	0.0217378326250437	0.16678164686456
GO:0030159	signaling receptor complex adaptor activity	16/3458	52/18639	0.307692307692308	1.65849535080304	0.0229872410735853	0.175359810475636
GO:0031406	carboxylic acid binding	46/3458	187/18639	0.245989304812834	1.32590938473291	0.02327697208666	0.176561123498245
GO:0016879	ligase activity, forming carbon-nitrogen bonds	15/3458	48/18639	0.3125	1.68440934065934	0.0236743876072081	0.178561059071315
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	5/3458	10/18639	0.5	2.69505494505495	0.0241212710397358	0.17984280506904
GO:1905394	retromer complex binding	5/3458	10/18639	0.5	2.69505494505495	0.0241212710397358	0.17984280506904
GO:0001223	transcription coactivator binding	14/3458	44/18639	0.318181818181818	1.71503496503496	0.0242484680991964	0.17984280506904
GO:0015036	disulfide oxidoreductase activity	13/3458	40/18639	0.325	1.75178571428571	0.0246607272170064	0.181293054041961
GO:0051059	NF-kappaB binding	11/3458	32/18639	0.34375	1.85285027472527	0.0247156073675183	0.181293054041961
GO:0051787	misfolded protein binding	7/3458	17/18639	0.411764705882353	2.21945701357466	0.0257094602077559	0.187552619548383
GO:0003713	transcription coactivator activity	60/3458	256/18639	0.234375	1.26330700549451	0.0284981098635909	0.202946529887699
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	8/3458	21/18639	0.380952380952381	2.05337519623234	0.0285499227174159	0.202946529887699
GO:0009931	calcium-dependent protein serine/threonine kinase activity	8/3458	21/18639	0.380952380952381	2.05337519623234	0.0285499227174159	0.202946529887699
GO:0010314	phosphatidylinositol-5-phosphate binding	8/3458	21/18639	0.380952380952381	2.05337519623234	0.0285499227174159	0.202946529887699
GO:0000149	SNARE binding	28/3458	106/18639	0.264150943396226	1.42380261248186	0.0285797360441104	0.202946529887699
GO:0004715	non-membrane spanning protein tyrosine kinase activity	14/3458	45/18639	0.311111111111111	1.67692307692308	0.0293590690902153	0.207377551510251
GO:0005537	D-mannose binding	9/3458	25/18639	0.36	1.94043956043956	0.030155029834151	0.210769449364354
GO:0047617	fatty acyl-CoA hydrolase activity	9/3458	25/18639	0.36	1.94043956043956	0.030155029834151	0.210769449364354
GO:0019209	kinase activator activity	37/3458	148/18639	0.25	1.34752747252747	0.0307540537447967	0.211930134907103
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	10/3458	29/18639	0.344827586206897	1.85865858279651	0.0308944499994474	0.211930134907103
GO:0005161	platelet-derived growth factor receptor binding	6/3458	14/18639	0.428571428571429	2.31004709576138	0.0312735854507111	0.211930134907103
GO:0005545	1-phosphatidylinositol binding	6/3458	14/18639	0.428571428571429	2.31004709576138	0.0312735854507111	0.211930134907103
GO:0044548	S100 protein binding	6/3458	14/18639	0.428571428571429	2.31004709576138	0.0312735854507111	0.211930134907103
GO:0098847	sequence-specific single stranded DNA binding	6/3458	14/18639	0.428571428571429	2.31004709576138	0.0312735854507111	0.211930134907103
GO:0048306	calcium-dependent protein binding	22/3458	80/18639	0.275	1.48228021978022	0.0318363372484447	0.214654092053907
GO:0050661	NADP binding	16/3458	54/18639	0.296296296296296	1.5970695970696	0.0324495021829757	0.216600427071363
GO:0051287	NAD binding	16/3458	54/18639	0.296296296296296	1.5970695970696	0.0324495021829757	0.216600427071363
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	19/3458	67/18639	0.283582089552239	1.52853862555355	0.0327049530862837	0.217219464528302
GO:0004713	protein tyrosine kinase activity	35/3458	140/18639	0.25	1.34752747252747	0.0348529592808788	0.230340102178085
GO:0004706	JUN kinase kinase kinase activity	7/3458	18/18639	0.388888888888889	2.09615384615385	0.0354909647284783	0.231124087378139
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	7/3458	18/18639	0.388888888888889	2.09615384615385	0.0354909647284783	0.231124087378139
GO:0098641	cadherin binding involved in cell-cell adhesion	7/3458	18/18639	0.388888888888889	2.09615384615385	0.0354909647284783	0.231124087378139
GO:0045309	protein phosphorylated amino acid binding	17/3458	59/18639	0.288135593220339	1.55308251070963	0.0362765484209216	0.235093165737526
GO:0048487	beta-tubulin binding	13/3458	42/18639	0.30952380952381	1.66836734693878	0.0364718634177699	0.235217090158081
GO:0000099	sulfur amino acid transmembrane transporter activity	5/3458	11/18639	0.454545454545455	2.45004995004995	0.0375827867185417	0.236665189949307
GO:0002162	dystroglycan binding	5/3458	11/18639	0.454545454545455	2.45004995004995	0.0375827867185417	0.236665189949307
GO:0008432	JUN kinase binding	5/3458	11/18639	0.454545454545455	2.45004995004995	0.0375827867185417	0.236665189949307
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	5/3458	11/18639	0.454545454545455	2.45004995004995	0.0375827867185417	0.236665189949307
GO:0042608	T cell receptor binding	5/3458	11/18639	0.454545454545455	2.45004995004995	0.0375827867185417	0.236665189949307
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	11/3458	34/18639	0.323529411764706	1.74385908209438	0.0384060241296127	0.239437214038523
GO:0016289	acyl-CoA hydrolase activity	9/3458	26/18639	0.346153846153846	1.86580726965342	0.0387404031702778	0.239437214038523
GO:0019865	immunoglobulin binding	9/3458	26/18639	0.346153846153846	1.86580726965342	0.0387404031702778	0.239437214038523
GO:0051139	metal cation:proton antiporter activity	9/3458	26/18639	0.346153846153846	1.86580726965342	0.0387404031702778	0.239437214038523
GO:0005504	fatty acid binding	14/3458	47/18639	0.297872340425532	1.60556464811784	0.0418651839882055	0.257557698729283
GO:0031490	chromatin DNA binding	32/3458	128/18639	0.25	1.34752747252747	0.0421260916393214	0.257974001552725
GO:0005178	integrin binding	39/3458	161/18639	0.242236024844721	1.30567879325643	0.0427400658386591	0.260538757509635
GO:0003714	transcription corepressor activity	48/3458	204/18639	0.235294117647059	1.26826115061409	0.0431860453096749	0.262060774947345
GO:0048156	tau protein binding	13/3458	43/18639	0.302325581395349	1.62956810631229	0.0436836204165727	0.262914576739373
GO:0015399	primary active transmembrane transporter activity	40/3458	166/18639	0.240963855421687	1.29882166026744	0.0437206262443002	0.262914576739373
GO:0004865	protein serine/threonine phosphatase inhibitor activity	6/3458	15/18639	0.4	2.15604395604396	0.0441356454617318	0.263040565586661
GO:0061578	K63-linked deubiquitinase activity	6/3458	15/18639	0.4	2.15604395604396	0.0441356454617318	0.263040565586661
GO:0017124	SH3 domain binding	29/3458	115/18639	0.252173913043478	1.35924510272336	0.0462014967515717	0.271713648296688
GO:0035401	histone H3Y41 kinase activity	29/3458	115/18639	0.252173913043478	1.35924510272336	0.0462014967515717	0.271713648296688
GO:0140801	histone H2AXY142 kinase activity	29/3458	115/18639	0.252173913043478	1.35924510272336	0.0462014967515717	0.271713648296688
GO:0140566	histone reader activity	11/3458	35/18639	0.314285714285714	1.69403453689168	0.0469222372243591	0.274742046905787
GO:0005164	tumor necrosis factor receptor binding	10/3458	31/18639	0.32258064516129	1.7387451258419	0.048133336537438	0.280602638766287
GO:0000295	adenine nucleotide transmembrane transporter activity	8/3458	23/18639	0.347826086956522	1.87482083134257	0.0487653698332341	0.282277761520142
GO:0015252	proton channel activity	9/3458	27/18639	0.333333333333333	1.7967032967033	0.0488435677237099	0.282277761520142
GO:0032266	phosphatidylinositol-3-phosphate binding	14/3458	48/18639	0.291666666666667	1.57211538461538	0.0493555119097925	0.28400693275678
GO:0004601	peroxidase activity	16/3458	57/18639	0.280701754385965	1.51301330248699	0.0515694607225963	0.295473090406292
GO:0043014	alpha-tubulin binding	13/3458	44/18639	0.295454545454545	1.59253246753247	0.0518338455819241	0.295718734409695
GO:0140296	general transcription initiation factor binding	15/3458	53/18639	0.283018867924528	1.5255027990877	0.0545868628025763	0.304910648134132
GO:0004126	cytidine deaminase activity	5/3458	12/18639	0.416666666666667	2.24587912087912	0.054815397417372	0.304910648134132
GO:0004300	enoyl-CoA hydratase activity	5/3458	12/18639	0.416666666666667	2.24587912087912	0.054815397417372	0.304910648134132
GO:0015269	calcium-activated potassium channel activity	5/3458	12/18639	0.416666666666667	2.24587912087912	0.054815397417372	0.304910648134132
GO:0035197	siRNA binding	5/3458	12/18639	0.416666666666667	2.24587912087912	0.054815397417372	0.304910648134132
GO:0043047	single-stranded telomeric DNA binding	5/3458	12/18639	0.416666666666667	2.24587912087912	0.054815397417372	0.304910648134132
GO:0008408	3'-5' exonuclease activity	16/3458	58/18639	0.275862068965517	1.48692686623721	0.0593979521557012	0.320379592664842
GO:0000062	fatty-acyl-CoA binding	6/3458	16/18639	0.375	2.02129120879121	0.0598527181491679	0.320379592664842
GO:0015385	sodium:proton antiporter activity	6/3458	16/18639	0.375	2.02129120879121	0.0598527181491679	0.320379592664842
GO:0034450	ubiquitin-ubiquitin ligase activity	6/3458	16/18639	0.375	2.02129120879121	0.0598527181491679	0.320379592664842
GO:0070411	I-SMAD binding	6/3458	16/18639	0.375	2.02129120879121	0.0598527181491679	0.320379592664842
GO:0140327	flippase activity	6/3458	16/18639	0.375	2.02129120879121	0.0598527181491679	0.320379592664842
GO:0050840	extracellular matrix binding	18/3458	67/18639	0.26865671641791	1.44808922420863	0.0598949131952364	0.320379592664842
GO:0046875	ephrin receptor binding	9/3458	28/18639	0.321428571428571	1.73253532182104	0.0605401688733352	0.320379592664842
GO:0051393	alpha-actinin binding	9/3458	28/18639	0.321428571428571	1.73253532182104	0.0605401688733352	0.320379592664842
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	9/3458	28/18639	0.321428571428571	1.73253532182104	0.0605401688733352	0.320379592664842
GO:0001091	RNA polymerase II general transcription initiation factor binding	8/3458	24/18639	0.333333333333333	1.7967032967033	0.0616534456919741	0.320379592664842
GO:0019957	C-C chemokine binding	8/3458	24/18639	0.333333333333333	1.7967032967033	0.0616534456919741	0.320379592664842
GO:0030552	cAMP binding	8/3458	24/18639	0.333333333333333	1.7967032967033	0.0616534456919741	0.320379592664842
GO:0070300	phosphatidic acid binding	8/3458	24/18639	0.333333333333333	1.7967032967033	0.0616534456919741	0.320379592664842
GO:0001614	purinergic nucleotide receptor activity	7/3458	20/18639	0.35	1.88653846153846	0.0616760713969022	0.320379592664842
GO:0016502	nucleotide receptor activity	7/3458	20/18639	0.35	1.88653846153846	0.0616760713969022	0.320379592664842
GO:0052745	inositol phosphate phosphatase activity	7/3458	20/18639	0.35	1.88653846153846	0.0616760713969022	0.320379592664842
GO:0140098	catalytic activity, acting on RNA	84/3458	387/18639	0.217054263565891	1.16994633273703	0.0630593871125446	0.326295665873051
GO:0005518	collagen binding	19/3458	72/18639	0.263888888888889	1.42239010989011	0.0635884726310358	0.32776297668893
GO:0042287	MHC protein binding	12/3458	41/18639	0.292682926829268	1.57759313856875	0.0642715991168696	0.330009941619311
GO:0023023	MHC protein complex binding	11/3458	37/18639	0.297297297297297	1.6024651024651	0.0675933845622346	0.343870034114952
GO:0042805	actinin binding	11/3458	37/18639	0.297297297297297	1.6024651024651	0.0675933845622346	0.343870034114952
GO:0005548	phospholipid transporter activity	18/3458	68/18639	0.264705882352941	1.42679379444085	0.0678702444192682	0.343870034114952
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	16/3458	59/18639	0.271186440677966	1.461724715962	0.0680012651732939	0.343870034114952
GO:0008374	O-acyltransferase activity	15/3458	55/18639	0.272727272727273	1.47002997002997	0.0724662140513701	0.365065644371997
GO:0030295	protein kinase activator activity	33/3458	139/18639	0.237410071942446	1.27966637678868	0.0738602969274661	0.369403711832925
GO:0043236	laminin binding	9/3458	29/18639	0.310344827586207	1.67279272451686	0.0738807423665849	0.369403711832925
GO:0004535	poly(A)-specific ribonuclease activity	5/3458	13/18639	0.384615384615385	2.0731191885038	0.075872543072393	0.375504940414219
GO:0140333	glycerophospholipid flippase activity	5/3458	13/18639	0.384615384615385	2.0731191885038	0.075872543072393	0.375504940414219
GO:0017025	TBP-class protein binding	8/3458	25/18639	0.32	1.72483516483516	0.0764762296250673	0.375504940414219
GO:0098531	ligand-modulated transcription factor activity	16/3458	60/18639	0.266666666666667	1.43736263736264	0.0774003993781557	0.375504940414219
GO:0001540	amyloid-beta binding	21/3458	83/18639	0.253012048192771	1.36376274328082	0.0781388519974016	0.375504940414219
GO:0019200	carbohydrate kinase activity	7/3458	21/18639	0.333333333333333	1.7967032967033	0.0782391457366455	0.375504940414219
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	6/3458	17/18639	0.352941176470588	1.90239172592114	0.0784763133899379	0.375504940414219
GO:0008429	phosphatidylethanolamine binding	6/3458	17/18639	0.352941176470588	1.90239172592114	0.0784763133899379	0.375504940414219
GO:0031489	myosin V binding	6/3458	17/18639	0.352941176470588	1.90239172592114	0.0784763133899379	0.375504940414219
GO:0032977	membrane insertase activity	6/3458	17/18639	0.352941176470588	1.90239172592114	0.0784763133899379	0.375504940414219
GO:0036041	long-chain fatty acid binding	6/3458	17/18639	0.352941176470588	1.90239172592114	0.0784763133899379	0.375504940414219
GO:1901567	fatty acid derivative binding	6/3458	17/18639	0.352941176470588	1.90239172592114	0.0784763133899379	0.375504940414219
GO:0031491	nucleosome binding	19/3458	74/18639	0.256756756756757	1.38394713394713	0.0802438306995458	0.382591121371049
GO:0160215	deacylase activity	17/3458	65/18639	0.261538461538462	1.40972104818259	0.0818623774262389	0.388919124071277
GO:0043495	protein-membrane adaptor activity	13/3458	47/18639	0.276595744680851	1.49088145896657	0.0822890378976823	0.389559807068815
GO:0016835	carbon-oxygen lyase activity	20/3458	79/18639	0.253164556962025	1.3645847823063	0.0836283245572746	0.394501107010465
GO:0015035	protein-disulfide reductase activity	10/3458	34/18639	0.294117647058824	1.58532643826761	0.0843585022699129	0.396544368064555
GO:0004712	protein serine/threonine/tyrosine kinase activity	12/3458	43/18639	0.27906976744186	1.50421671351904	0.0876655087435819	0.410643698851515
GO:0005080	protein kinase C binding	14/3458	52/18639	0.269230769230769	1.45118343195266	0.0883983302008321	0.412038257121759
GO:0015215	nucleotide transmembrane transporter activity	9/3458	30/18639	0.3	1.61703296703297	0.0888891520981771	0.412038257121759
GO:0070566	adenylyltransferase activity	9/3458	30/18639	0.3	1.61703296703297	0.0888891520981771	0.412038257121759
GO:0003725	double-stranded RNA binding	19/3458	75/18639	0.253333333333333	1.36549450549451	0.0895605196349886	0.413713819075121
GO:0016829	lyase activity	45/3458	200/18639	0.225	1.21277472527473	0.0903021572567586	0.415297478593805
GO:0001637	G protein-coupled chemoattractant receptor activity	8/3458	26/18639	0.307692307692308	1.65849535080304	0.0932477080494182	0.415297478593805
GO:0004950	chemokine receptor activity	8/3458	26/18639	0.307692307692308	1.65849535080304	0.0932477080494182	0.415297478593805
GO:0008198	ferrous iron binding	8/3458	26/18639	0.307692307692308	1.65849535080304	0.0932477080494182	0.415297478593805
GO:0015216	purine nucleotide transmembrane transporter activity	8/3458	26/18639	0.307692307692308	1.65849535080304	0.0932477080494182	0.415297478593805
GO:0043548	phosphatidylinositol 3-kinase binding	8/3458	26/18639	0.307692307692308	1.65849535080304	0.0932477080494182	0.415297478593805
GO:0004955	prostaglandin receptor activity	4/3458	10/18639	0.4	2.15604395604396	0.0967253751452584	0.415297478593805
GO:0005381	iron ion transmembrane transporter activity	4/3458	10/18639	0.4	2.15604395604396	0.0967253751452584	0.415297478593805
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	4/3458	10/18639	0.4	2.15604395604396	0.0967253751452584	0.415297478593805
GO:0030957	Tat protein binding	4/3458	10/18639	0.4	2.15604395604396	0.0967253751452584	0.415297478593805
GO:0031434	mitogen-activated protein kinase kinase binding	4/3458	10/18639	0.4	2.15604395604396	0.0967253751452584	0.415297478593805
GO:0031996	thioesterase binding	4/3458	10/18639	0.4	2.15604395604396	0.0967253751452584	0.415297478593805
GO:0070513	death domain binding	4/3458	10/18639	0.4	2.15604395604396	0.0967253751452584	0.415297478593805
GO:0071723	lipopeptide binding	4/3458	10/18639	0.4	2.15604395604396	0.0967253751452584	0.415297478593805
GO:0097177	mitochondrial ribosome binding	4/3458	10/18639	0.4	2.15604395604396	0.0967253751452584	0.415297478593805
GO:0098505	G-rich strand telomeric DNA binding	4/3458	10/18639	0.4	2.15604395604396	0.0967253751452584	0.415297478593805
GO:0033691	sialic acid binding	7/3458	22/18639	0.318181818181818	1.71503496503496	0.0971293062219414	0.415297478593805
GO:0070034	telomerase RNA binding	7/3458	22/18639	0.318181818181818	1.71503496503496	0.0971293062219414	0.415297478593805
GO:0140517	protein-RNA adaptor activity	7/3458	22/18639	0.318181818181818	1.71503496503496	0.0971293062219414	0.415297478593805
GO:0000175	3'-5'-RNA exonuclease activity	10/3458	35/18639	0.285714285714286	1.54003139717425	0.0993330082881344	0.415297478593805
GO:0043015	gamma-tubulin binding	10/3458	35/18639	0.285714285714286	1.54003139717425	0.0993330082881344	0.415297478593805
GO:0005096	GTPase activator activity	59/3458	271/18639	0.217712177121771	1.17349255910142	0.0994259668612212	0.415297478593805
GO:0017075	syntaxin-1 binding	6/3458	18/18639	0.333333333333333	1.7967032967033	0.0999689877206678	0.415297478593805
GO:0032393	MHC class I receptor activity	6/3458	18/18639	0.333333333333333	1.7967032967033	0.0999689877206678	0.415297478593805
GO:0070064	proline-rich region binding	6/3458	18/18639	0.333333333333333	1.7967032967033	0.0999689877206678	0.415297478593805
GO:0004864	protein phosphatase inhibitor activity	14/3458	53/18639	0.264150943396226	1.42380261248186	0.100535780036103	0.415297478593805
GO:0005246	calcium channel regulator activity	14/3458	53/18639	0.264150943396226	1.42380261248186	0.100535780036103	0.415297478593805
GO:0051018	protein kinase A binding	14/3458	53/18639	0.264150943396226	1.42380261248186	0.100535780036103	0.415297478593805
GO:0004705	JUN kinase activity	5/3458	14/18639	0.357142857142857	1.92503924646782	0.100649741751105	0.415297478593805
GO:0016530	metallochaperone activity	5/3458	14/18639	0.357142857142857	1.92503924646782	0.100649741751105	0.415297478593805
GO:0019763	immunoglobulin receptor activity	5/3458	14/18639	0.357142857142857	1.92503924646782	0.100649741751105	0.415297478593805
GO:0032036	myosin heavy chain binding	5/3458	14/18639	0.357142857142857	1.92503924646782	0.100649741751105	0.415297478593805
GO:0034236	protein kinase A catalytic subunit binding	5/3458	14/18639	0.357142857142857	1.92503924646782	0.100649741751105	0.415297478593805
GO:0071933	Arp2/3 complex binding	5/3458	14/18639	0.357142857142857	1.92503924646782	0.100649741751105	0.415297478593805
GO:0001046	core promoter sequence-specific DNA binding	12/3458	44/18639	0.272727272727273	1.47002997002997	0.101102382429203	0.415297478593805
GO:0016248	channel inhibitor activity	12/3458	44/18639	0.272727272727273	1.47002997002997	0.101102382429203	0.415297478593805
GO:0005516	calmodulin binding	46/3458	207/18639	0.222222222222222	1.1978021978022	0.102772814985661	0.420864134987294
GO:0070273	phosphatidylinositol-4-phosphate binding	9/3458	31/18639	0.290322580645161	1.56487061325771	0.105561985736661	0.429650155361106
GO:0072349	modified amino acid transmembrane transporter activity	9/3458	31/18639	0.290322580645161	1.56487061325771	0.105561985736661	0.429650155361106
GO:0004532	RNA exonuclease activity	11/3458	40/18639	0.275	1.48228021978022	0.108171447089177	0.43496651163871
GO:0030331	nuclear estrogen receptor binding	11/3458	40/18639	0.275	1.48228021978022	0.108171447089177	0.43496651163871
GO:0050997	quaternary ammonium group binding	11/3458	40/18639	0.275	1.48228021978022	0.108171447089177	0.43496651163871
GO:0071949	FAD binding	11/3458	40/18639	0.275	1.48228021978022	0.108171447089177	0.43496651163871
GO:0005507	copper ion binding	16/3458	63/18639	0.253968253968254	1.36891679748823	0.110497915479038	0.442987138632181
GO:0008320	protein transmembrane transporter activity	8/3458	27/18639	0.296296296296296	1.5970695970696	0.111944188186559	0.447441590506155
GO:0140463	chromatin-protein adaptor activity	14/3458	54/18639	0.259259259259259	1.3974358974359	0.113637871753661	0.452855399376528
GO:0032934	sterol binding	17/3458	68/18639	0.25	1.34752747252747	0.114629805303053	0.455448779998738
GO:0141110	transporter inhibitor activity	12/3458	45/18639	0.266666666666667	1.43736263736264	0.115698076573757	0.457197948930713
GO:0000993	RNA polymerase II complex binding	10/3458	36/18639	0.277777777777778	1.49725274725275	0.115754986321034	0.457197948930713
GO:0016493	C-C chemokine receptor activity	7/3458	23/18639	0.304347826086957	1.64046822742475	0.118288528392001	0.463437383594229
GO:0001786	phosphatidylserine binding	15/3458	59/18639	0.254237288135593	1.37036692121438	0.118723284785937	0.463437383594229
GO:0004879	nuclear receptor activity	15/3458	59/18639	0.254237288135593	1.37036692121438	0.118723284785937	0.463437383594229
GO:0031593	polyubiquitin modification-dependent protein binding	15/3458	59/18639	0.254237288135593	1.37036692121438	0.118723284785937	0.463437383594229
GO:0032813	tumor necrosis factor receptor superfamily binding	13/3458	50/18639	0.26	1.40142857142857	0.122145241946754	0.46967588288258
GO:0019838	growth factor binding	31/3458	136/18639	0.227941176470588	1.2286279896574	0.123057750256106	0.46967588288258
GO:0140789	histone phosphatase activity	31/3458	136/18639	0.227941176470588	1.2286279896574	0.123057750256106	0.46967588288258
GO:0005346	purine ribonucleotide transmembrane transporter activity	6/3458	19/18639	0.315789473684211	1.70213996529786	0.124211273248633	0.46967588288258
GO:0046624	sphingolipid transporter activity	6/3458	19/18639	0.315789473684211	1.70213996529786	0.124211273248633	0.46967588288258
GO:0070003	threonine-type peptidase activity	6/3458	19/18639	0.315789473684211	1.70213996529786	0.124211273248633	0.46967588288258
GO:0120227	acyl-CoA binding	6/3458	19/18639	0.315789473684211	1.70213996529786	0.124211273248633	0.46967588288258
GO:0140828	metal cation:monoatomic cation antiporter activity	11/3458	41/18639	0.268292682926829	1.44612704368802	0.124268058012357	0.46967588288258
GO:0030165	PDZ domain binding	20/3458	83/18639	0.240963855421687	1.29882166026744	0.124445514323682	0.46967588288258
GO:0061659	ubiquitin-like protein ligase activity	78/3458	372/18639	0.209677419354839	1.13018433179724	0.127241854697885	0.46967588288258
GO:0140313	molecular sequestering activity	14/3458	55/18639	0.254545454545455	1.37202797202797	0.127696486578833	0.46967588288258
GO:0004467	long-chain fatty acid-CoA ligase activity	5/3458	15/18639	0.333333333333333	1.7967032967033	0.128906789895792	0.46967588288258
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	5/3458	15/18639	0.333333333333333	1.7967032967033	0.128906789895792	0.46967588288258
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	5/3458	15/18639	0.333333333333333	1.7967032967033	0.128906789895792	0.46967588288258
GO:0004953	icosanoid receptor activity	5/3458	15/18639	0.333333333333333	1.7967032967033	0.128906789895792	0.46967588288258
GO:0005523	tropomyosin binding	5/3458	15/18639	0.333333333333333	1.7967032967033	0.128906789895792	0.46967588288258
GO:0008252	nucleotidase activity	5/3458	15/18639	0.333333333333333	1.7967032967033	0.128906789895792	0.46967588288258
GO:0010181	FMN binding	5/3458	15/18639	0.333333333333333	1.7967032967033	0.128906789895792	0.46967588288258
GO:0042809	nuclear vitamin D receptor binding	5/3458	15/18639	0.333333333333333	1.7967032967033	0.128906789895792	0.46967588288258
GO:0051371	muscle alpha-actinin binding	5/3458	15/18639	0.333333333333333	1.7967032967033	0.128906789895792	0.46967588288258
GO:0004954	prostanoid receptor activity	4/3458	11/18639	0.363636363636364	1.96003996003996	0.130521139960525	0.46967588288258
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	4/3458	11/18639	0.363636363636364	1.96003996003996	0.130521139960525	0.46967588288258
GO:0019203	carbohydrate phosphatase activity	4/3458	11/18639	0.363636363636364	1.96003996003996	0.130521139960525	0.46967588288258
GO:0019206	nucleoside kinase activity	4/3458	11/18639	0.363636363636364	1.96003996003996	0.130521139960525	0.46967588288258
GO:0047676	arachidonate-CoA ligase activity	4/3458	11/18639	0.363636363636364	1.96003996003996	0.130521139960525	0.46967588288258
GO:0048407	platelet-derived growth factor binding	4/3458	11/18639	0.363636363636364	1.96003996003996	0.130521139960525	0.46967588288258
GO:0050998	nitric-oxide synthase binding	4/3458	11/18639	0.363636363636364	1.96003996003996	0.130521139960525	0.46967588288258
GO:0097493	structural molecule activity conferring elasticity	4/3458	11/18639	0.363636363636364	1.96003996003996	0.130521139960525	0.46967588288258
GO:0048029	monosaccharide binding	18/3458	74/18639	0.243243243243243	1.31110781110781	0.130524159213061	0.46967588288258
GO:0030276	clathrin binding	12/3458	46/18639	0.260869565217391	1.40611562350693	0.131435760568241	0.471684785910219
GO:0046966	nuclear thyroid hormone receptor binding	8/3458	28/18639	0.285714285714286	1.54003139717425	0.132505795911848	0.472981918562344
GO:0051019	mitogen-activated protein kinase binding	8/3458	28/18639	0.285714285714286	1.54003139717425	0.132505795911848	0.472981918562344
GO:0030551	cyclic nucleotide binding	10/3458	37/18639	0.27027027027027	1.45678645678646	0.133592616602071	0.475589715103373
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	21/3458	89/18639	0.235955056179775	1.27182368193604	0.138601573484499	0.490803980376145
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	21/3458	89/18639	0.235955056179775	1.27182368193604	0.138601573484499	0.490803980376145
GO:0097110	scaffold protein binding	17/3458	70/18639	0.242857142857143	1.30902668759812	0.140293760419647	0.495481931640818
GO:0035035	histone acetyltransferase binding	7/3458	24/18639	0.291666666666667	1.57211538461538	0.1416088565626	0.496188513152418
GO:0050699	WW domain binding	7/3458	24/18639	0.291666666666667	1.57211538461538	0.1416088565626	0.496188513152418
GO:0060229	lipase activator activity	7/3458	24/18639	0.291666666666667	1.57211538461538	0.1416088565626	0.496188513152418
GO:0019212	phosphatase inhibitor activity	14/3458	56/18639	0.25	1.34752747252747	0.142694806389168	0.498470026385642
GO:0019239	deaminase activity	9/3458	33/18639	0.272727272727273	1.47002997002997	0.143753528208593	0.498470026385642
GO:0030296	protein tyrosine kinase activator activity	9/3458	33/18639	0.272727272727273	1.47002997002997	0.143753528208593	0.498470026385642
GO:0140311	protein sequestering activity	9/3458	33/18639	0.272727272727273	1.47002997002997	0.143753528208593	0.498470026385642
GO:0016247	channel regulator activity	37/3458	168/18639	0.220238095238095	1.18710753532182	0.144294495537303	0.498585220725664
GO:0140030	modification-dependent protein binding	38/3458	173/18639	0.219653179190751	1.18395477355015	0.144533693199125	0.498585220725664
GO:0016836	hydro-lyase activity	15/3458	61/18639	0.245901639344262	1.32543685822374	0.147134563555378	0.506249078212446
GO:0001784	phosphotyrosine residue binding	12/3458	47/18639	0.25531914893617	1.37619826981529	0.148286065483861	0.508899479231245
GO:0140793	histone H2AXY142 phosphatase activity	21/3458	90/18639	0.233333333333333	1.25769230769231	0.150766345340683	0.511677966615176
GO:0015095	magnesium ion transmembrane transporter activity	6/3458	20/18639	0.3	1.61703296703297	0.151012074042232	0.511677966615176
GO:0016004	phospholipase activator activity	6/3458	20/18639	0.3	1.61703296703297	0.151012074042232	0.511677966615176
GO:0016408	C-acyltransferase activity	6/3458	20/18639	0.3	1.61703296703297	0.151012074042232	0.511677966615176
GO:0042288	MHC class I protein binding	6/3458	20/18639	0.3	1.61703296703297	0.151012074042232	0.511677966615176
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	10/3458	38/18639	0.263157894736842	1.41844997108155	0.152794706283897	0.513805876294715
GO:0042162	telomeric DNA binding	10/3458	38/18639	0.263157894736842	1.41844997108155	0.152794706283897	0.513805876294715
GO:0043531	ADP binding	10/3458	38/18639	0.263157894736842	1.41844997108155	0.152794706283897	0.513805876294715
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	8/3458	29/18639	0.275862068965517	1.48692686623721	0.154839149643377	0.51807083903235
GO:0097472	cyclin-dependent protein kinase activity	8/3458	29/18639	0.275862068965517	1.48692686623721	0.154839149643377	0.51807083903235
GO:0001618	virus receptor activity	19/3458	81/18639	0.234567901234568	1.26434676434676	0.159546434891611	0.524494683272821
GO:0008200	ion channel inhibitor activity	11/3458	43/18639	0.255813953488372	1.37886532072579	0.160155239830852	0.524494683272821
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/3458	16/18639	0.3125	1.68440934065934	0.160295004326076	0.524494683272821
GO:0004707	MAP kinase activity	5/3458	16/18639	0.3125	1.68440934065934	0.160295004326076	0.524494683272821
GO:0005149	interleukin-1 receptor binding	5/3458	16/18639	0.3125	1.68440934065934	0.160295004326076	0.524494683272821
GO:0016722	oxidoreductase activity, acting on metal ions	5/3458	16/18639	0.3125	1.68440934065934	0.160295004326076	0.524494683272821
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	5/3458	16/18639	0.3125	1.68440934065934	0.160295004326076	0.524494683272821
GO:0097027	ubiquitin-protein transferase activator activity	5/3458	16/18639	0.3125	1.68440934065934	0.160295004326076	0.524494683272821
GO:0140328	floppase activity	5/3458	16/18639	0.3125	1.68440934065934	0.160295004326076	0.524494683272821
GO:0099106	ion channel regulator activity	35/3458	160/18639	0.21875	1.17908653846154	0.1623163102705	0.528888379599278
GO:0141108	transporter regulator activity	37/3458	170/18639	0.217647058823529	1.17314156431803	0.162430139052962	0.528888379599278
GO:0008175	tRNA methyltransferase activity	9/3458	34/18639	0.264705882352941	1.42679379444085	0.165135737546518	0.532652381504397
GO:0000340	RNA 7-methylguanosine cap binding	4/3458	12/18639	0.333333333333333	1.7967032967033	0.168374011232102	0.532652381504397
GO:0004875	complement receptor activity	4/3458	12/18639	0.333333333333333	1.7967032967033	0.168374011232102	0.532652381504397
GO:0005078	MAP-kinase scaffold activity	4/3458	12/18639	0.333333333333333	1.7967032967033	0.168374011232102	0.532652381504397
GO:0005095	GTPase inhibitor activity	4/3458	12/18639	0.333333333333333	1.7967032967033	0.168374011232102	0.532652381504397
GO:0016208	AMP binding	4/3458	12/18639	0.333333333333333	1.7967032967033	0.168374011232102	0.532652381504397
GO:0016840	carbon-nitrogen lyase activity	4/3458	12/18639	0.333333333333333	1.7967032967033	0.168374011232102	0.532652381504397
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	4/3458	12/18639	0.333333333333333	1.7967032967033	0.168374011232102	0.532652381504397
GO:0070008	serine-type exopeptidase activity	4/3458	12/18639	0.333333333333333	1.7967032967033	0.168374011232102	0.532652381504397
GO:0070410	co-SMAD binding	4/3458	12/18639	0.333333333333333	1.7967032967033	0.168374011232102	0.532652381504397
GO:0097371	MDM2/MDM4 family protein binding	4/3458	12/18639	0.333333333333333	1.7967032967033	0.168374011232102	0.532652381504397
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/3458	12/18639	0.333333333333333	1.7967032967033	0.168374011232102	0.532652381504397
GO:0016251	RNA polymerase II general transcription initiation factor activity	13/3458	53/18639	0.245283018867925	1.32210242587601	0.171222420576749	0.540382816713854
GO:0140272	exogenous protein binding	19/3458	82/18639	0.231707317073171	1.24892790136693	0.173497607853863	0.546271949256855
GO:0043178	alcohol binding	21/3458	92/18639	0.228260869565217	1.23035117056856	0.176814139608848	0.555404415006617
GO:0016791	phosphatase activity	57/3458	273/18639	0.208791208791209	1.12540755947349	0.178635443750647	0.55662468185547
GO:0001968	fibronectin binding	8/3458	30/18639	0.266666666666667	1.43736263736264	0.17882096693254	0.55662468185547
GO:0016790	thiolester hydrolase activity	11/3458	44/18639	0.25	1.34752747252747	0.179839525631402	0.55662468185547
GO:0001846	opsonin binding	6/3458	21/18639	0.285714285714286	1.54003139717425	0.180121245364467	0.55662468185547
GO:0035613	RNA stem-loop binding	6/3458	21/18639	0.285714285714286	1.54003139717425	0.180121245364467	0.55662468185547
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	6/3458	21/18639	0.285714285714286	1.54003139717425	0.180121245364467	0.55662468185547
GO:0072542	protein phosphatase activator activity	6/3458	21/18639	0.285714285714286	1.54003139717425	0.180121245364467	0.55662468185547
GO:0019783	ubiquitin-like protein peptidase activity	28/3458	127/18639	0.220472440944882	1.18837068443368	0.182210284354926	0.561779976013455
GO:0015459	potassium channel regulator activity	14/3458	59/18639	0.23728813559322	1.27900912646675	0.193034087232374	0.58001483735285
GO:0005227	calcium-activated cation channel activity	7/3458	26/18639	0.269230769230769	1.45118343195266	0.194087344326611	0.58001483735285
GO:0052742	phosphatidylinositol kinase activity	7/3458	26/18639	0.269230769230769	1.45118343195266	0.194087344326611	0.58001483735285
GO:0097602	cullin family protein binding	7/3458	26/18639	0.269230769230769	1.45118343195266	0.194087344326611	0.58001483735285
GO:0120014	phospholipid transfer activity	7/3458	26/18639	0.269230769230769	1.45118343195266	0.194087344326611	0.58001483735285
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	28/3458	128/18639	0.21875	1.17908653846154	0.194103713619837	0.58001483735285
GO:0004659	prenyltransferase activity	5/3458	17/18639	0.294117647058824	1.58532643826761	0.194386125549466	0.58001483735285
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	5/3458	17/18639	0.294117647058824	1.58532643826761	0.194386125549466	0.58001483735285
GO:0016805	dipeptidase activity	5/3458	17/18639	0.294117647058824	1.58532643826761	0.194386125549466	0.58001483735285
GO:0030169	low-density lipoprotein particle binding	5/3458	17/18639	0.294117647058824	1.58532643826761	0.194386125549466	0.58001483735285
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	5/3458	17/18639	0.294117647058824	1.58532643826761	0.194386125549466	0.58001483735285
GO:0045125	bioactive lipid receptor activity	5/3458	17/18639	0.294117647058824	1.58532643826761	0.194386125549466	0.58001483735285
GO:0046965	nuclear retinoid X receptor binding	5/3458	17/18639	0.294117647058824	1.58532643826761	0.194386125549466	0.58001483735285
GO:0048038	quinone binding	5/3458	17/18639	0.294117647058824	1.58532643826761	0.194386125549466	0.58001483735285
GO:0005126	cytokine receptor binding	57/3458	275/18639	0.207272727272727	1.11722277722278	0.194641683246499	0.58001483735285
GO:0042578	phosphoric ester hydrolase activity	74/3458	363/18639	0.203856749311295	1.09881028062846	0.199518317956651	0.593222615750845
GO:0046915	transition metal ion transmembrane transporter activity	11/3458	45/18639	0.244444444444444	1.31758241758242	0.200591170914758	0.593767656698894
GO:0140303	intramembrane lipid transporter activity	11/3458	45/18639	0.244444444444444	1.31758241758242	0.200591170914758	0.593767656698894
GO:0061630	ubiquitin protein ligase activity	72/3458	353/18639	0.203966005665722	1.09939918438502	0.201815117721467	0.59448581647041
GO:0004527	exonuclease activity	19/3458	84/18639	0.226190476190476	1.21919152276295	0.2032087107174	0.59448581647041
GO:0016878	acid-thiol ligase activity	8/3458	31/18639	0.258064516129032	1.39099610067352	0.204302351696324	0.59448581647041
GO:0015605	organophosphate ester transmembrane transporter activity	12/3458	50/18639	0.24	1.29362637362637	0.205043128019132	0.59448581647041
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	4/3458	13/18639	0.307692307692308	1.65849535080304	0.209485774858639	0.59448581647041
GO:0004465	lipoprotein lipase activity	4/3458	13/18639	0.307692307692308	1.65849535080304	0.209485774858639	0.59448581647041
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	4/3458	13/18639	0.307692307692308	1.65849535080304	0.209485774858639	0.59448581647041
GO:0008253	5'-nucleotidase activity	4/3458	13/18639	0.307692307692308	1.65849535080304	0.209485774858639	0.59448581647041
GO:0015651	quaternary ammonium group transmembrane transporter activity	4/3458	13/18639	0.307692307692308	1.65849535080304	0.209485774858639	0.59448581647041
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	4/3458	13/18639	0.307692307692308	1.65849535080304	0.209485774858639	0.59448581647041
GO:0019855	calcium channel inhibitor activity	4/3458	13/18639	0.307692307692308	1.65849535080304	0.209485774858639	0.59448581647041
GO:0070700	BMP receptor binding	4/3458	13/18639	0.307692307692308	1.65849535080304	0.209485774858639	0.59448581647041
GO:0004407	histone deacetylase activity	6/3458	22/18639	0.272727272727273	1.47002997002997	0.211243222542913	0.59448581647041
GO:0008970	phospholipase A1 activity	6/3458	22/18639	0.272727272727273	1.47002997002997	0.211243222542913	0.59448581647041
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	6/3458	22/18639	0.272727272727273	1.47002997002997	0.211243222542913	0.59448581647041
GO:0016881	acid-amino acid ligase activity	6/3458	22/18639	0.272727272727273	1.47002997002997	0.211243222542913	0.59448581647041
GO:0030021	extracellular matrix structural constituent conferring compression resistance	6/3458	22/18639	0.272727272727273	1.47002997002997	0.211243222542913	0.59448581647041
GO:0031683	G-protein beta/gamma-subunit complex binding	6/3458	22/18639	0.272727272727273	1.47002997002997	0.211243222542913	0.59448581647041
GO:0033558	protein lysine deacetylase activity	6/3458	22/18639	0.272727272727273	1.47002997002997	0.211243222542913	0.59448581647041
GO:0050321	tau-protein kinase activity	6/3458	22/18639	0.272727272727273	1.47002997002997	0.211243222542913	0.59448581647041
GO:0061133	endopeptidase activator activity	6/3458	22/18639	0.272727272727273	1.47002997002997	0.211243222542913	0.59448581647041
GO:0140035	ubiquitin-like protein reader activity	6/3458	22/18639	0.272727272727273	1.47002997002997	0.211243222542913	0.59448581647041
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	14/3458	60/18639	0.233333333333333	1.25769230769231	0.211458241631225	0.59448581647041
GO:0004869	cysteine-type endopeptidase inhibitor activity	9/3458	36/18639	0.25	1.34752747252747	0.211966478381959	0.59448581647041
GO:0044390	ubiquitin-like protein conjugating enzyme binding	9/3458	36/18639	0.25	1.34752747252747	0.211966478381959	0.59448581647041
GO:0120013	lipid transfer activity	15/3458	65/18639	0.230769230769231	1.24387151310228	0.213740055029884	0.598203298668544
GO:0001727	lipid kinase activity	10/3458	41/18639	0.24390243902439	1.31466094880729	0.217815227348304	0.604539144511405
GO:0016877	ligase activity, forming carbon-sulfur bonds	10/3458	41/18639	0.24390243902439	1.31466094880729	0.217815227348304	0.604539144511405
GO:0017080	sodium channel regulator activity	10/3458	41/18639	0.24390243902439	1.31466094880729	0.217815227348304	0.604539144511405
GO:0042169	SH2 domain binding	10/3458	41/18639	0.24390243902439	1.31466094880729	0.217815227348304	0.604539144511405
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	7/3458	27/18639	0.259259259259259	1.3974358974359	0.222837448975629	0.617195009092251
GO:0005048	signal sequence binding	12/3458	51/18639	0.235294117647059	1.26826115061409	0.225821714011576	0.622876008688954
GO:0016830	carbon-carbon lyase activity	12/3458	51/18639	0.235294117647059	1.26826115061409	0.225821714011576	0.622876008688954
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	14/3458	61/18639	0.229508196721311	1.23707440100883	0.230618486164456	0.625834776073859
GO:0019905	syntaxin binding	14/3458	61/18639	0.229508196721311	1.23707440100883	0.230618486164456	0.625834776073859
GO:0003746	translation elongation factor activity	5/3458	18/18639	0.277777777777778	1.49725274725275	0.230700409329773	0.625834776073859
GO:0008525	phosphatidylcholine transporter activity	5/3458	18/18639	0.277777777777778	1.49725274725275	0.230700409329773	0.625834776073859
GO:0015172	acidic amino acid transmembrane transporter activity	5/3458	18/18639	0.277777777777778	1.49725274725275	0.230700409329773	0.625834776073859
GO:1990381	ubiquitin-specific protease binding	5/3458	18/18639	0.277777777777778	1.49725274725275	0.230700409329773	0.625834776073859
GO:0022884	macromolecule transmembrane transporter activity	8/3458	32/18639	0.25	1.34752747252747	0.231113516557612	0.625834776073859
GO:0031369	translation initiation factor binding	8/3458	32/18639	0.25	1.34752747252747	0.231113516557612	0.625834776073859
GO:0140142	nucleocytoplasmic carrier activity	8/3458	32/18639	0.25	1.34752747252747	0.231113516557612	0.625834776073859
GO:0051082	unfolded protein binding	26/3458	121/18639	0.214876033057851	1.1582054309327	0.233371253483142	0.630669278137642
GO:1902936	phosphatidylinositol bisphosphate binding	24/3458	111/18639	0.216216216216216	1.16542916542917	0.234419650603691	0.631998066599014
GO:0030971	receptor tyrosine kinase binding	18/3458	81/18639	0.222222222222222	1.1978021978022	0.234809768564128	0.631998066599014
GO:0043394	proteoglycan binding	9/3458	37/18639	0.243243243243243	1.31110781110781	0.237158076811209	0.637034270710189
GO:0016859	cis-trans isomerase activity	10/3458	42/18639	0.238095238095238	1.28335949764521	0.24162893741524	0.645149262898691
GO:0019894	kinesin binding	10/3458	42/18639	0.238095238095238	1.28335949764521	0.24162893741524	0.645149262898691
GO:0043175	RNA polymerase core enzyme binding	10/3458	42/18639	0.238095238095238	1.28335949764521	0.24162893741524	0.645149262898691
GO:0005158	insulin receptor binding	6/3458	23/18639	0.260869565217391	1.40611562350693	0.244050761655	0.650314903811228
GO:0042826	histone deacetylase binding	27/3458	127/18639	0.21259842519685	1.14592887427533	0.24638141887898	0.655217518333543
GO:0052689	carboxylic ester hydrolase activity	20/3458	92/18639	0.217391304347826	1.17176301958911	0.251535189655932	0.655887283719817
GO:0051540	metal cluster binding	17/3458	77/18639	0.220779220779221	1.19002426145283	0.252045732564903	0.655887283719817
GO:0045499	chemorepellent activity	7/3458	28/18639	0.25	1.34752747252747	0.25294799999689	0.655887283719817
GO:0050698	proteoglycan sulfotransferase activity	7/3458	28/18639	0.25	1.34752747252747	0.25294799999689	0.655887283719817
GO:0097718	disordered domain specific binding	7/3458	28/18639	0.25	1.34752747252747	0.25294799999689	0.655887283719817
GO:0005313	L-glutamate transmembrane transporter activity	4/3458	14/18639	0.285714285714286	1.54003139717425	0.253020188101652	0.655887283719817
GO:0008191	metalloendopeptidase inhibitor activity	4/3458	14/18639	0.285714285714286	1.54003139717425	0.253020188101652	0.655887283719817
GO:0008195	phosphatidate phosphatase activity	4/3458	14/18639	0.285714285714286	1.54003139717425	0.253020188101652	0.655887283719817
GO:0008474	palmitoyl-(protein) hydrolase activity	4/3458	14/18639	0.285714285714286	1.54003139717425	0.253020188101652	0.655887283719817
GO:0019992	diacylglycerol binding	4/3458	14/18639	0.285714285714286	1.54003139717425	0.253020188101652	0.655887283719817
GO:0046030	inositol trisphosphate phosphatase activity	4/3458	14/18639	0.285714285714286	1.54003139717425	0.253020188101652	0.655887283719817
GO:0070742	C2H2 zinc finger domain binding	4/3458	14/18639	0.285714285714286	1.54003139717425	0.253020188101652	0.655887283719817
GO:0098599	palmitoyl hydrolase activity	4/3458	14/18639	0.285714285714286	1.54003139717425	0.253020188101652	0.655887283719817
GO:0061135	endopeptidase regulator activity	38/3458	184/18639	0.206521739130435	1.11317486860965	0.257045529608417	0.665030585324102
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	8/3458	33/18639	0.242424242424242	1.30669330669331	0.259068712829298	0.668968533127878
GO:0030414	peptidase inhibitor activity	35/3458	169/18639	0.207100591715976	1.11629494765589	0.261804660494069	0.669777705971472
GO:0004725	protein tyrosine phosphatase activity	21/3458	98/18639	0.214285714285714	1.15502354788069	0.267275045273666	0.669777705971472
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	11/3458	48/18639	0.229166666666667	1.23523351648352	0.268358554783085	0.669777705971472
GO:0034987	immunoglobulin receptor binding	5/3458	19/18639	0.263157894736842	1.41844997108155	0.268732243644466	0.669777705971472
GO:0042577	lipid phosphatase activity	5/3458	19/18639	0.263157894736842	1.41844997108155	0.268732243644466	0.669777705971472
GO:0042834	peptidoglycan binding	5/3458	19/18639	0.263157894736842	1.41844997108155	0.268732243644466	0.669777705971472
GO:0140036	ubiquitin-modified protein reader activity	5/3458	19/18639	0.263157894736842	1.41844997108155	0.268732243644466	0.669777705971472
GO:0042393	histone binding	50/3458	247/18639	0.202429149797571	1.09111536237042	0.268888795327546	0.669777705971472
GO:0043539	protein serine/threonine kinase activator activity	16/3458	73/18639	0.219178082191781	1.18139394851724	0.270766043825246	0.669777705971472
GO:1990841	promoter-specific chromatin binding	15/3458	68/18639	0.220588235294118	1.18899482870071	0.270963595094523	0.669777705971472
GO:0042625	ATPase-coupled ion transmembrane transporter activity	6/3458	24/18639	0.25	1.34752747252747	0.278198063352467	0.669777705971472
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	6/3458	24/18639	0.25	1.34752747252747	0.278198063352467	0.669777705971472
GO:0046961	proton-transporting ATPase activity, rotational mechanism	6/3458	24/18639	0.25	1.34752747252747	0.278198063352467	0.669777705971472
GO:0050431	transforming growth factor beta binding	6/3458	24/18639	0.25	1.34752747252747	0.278198063352467	0.669777705971472
GO:0001094	TFIID-class transcription factor complex binding	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0004090	carbonyl reductase (NADPH) activity	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0004382	GDP phosphatase activity	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0004445	inositol-polyphosphate 5-phosphatase activity	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0005528	FK506 binding	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0008140	cAMP response element binding protein binding	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0016175	superoxide-generating NAD(P)H oxidase activity	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0016427	tRNA (cytidine) methyltransferase activity	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0016868	intramolecular phosphotransferase activity	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0019911	structural constituent of myelin sheath	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0032395	MHC class II receptor activity	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0043208	glycosphingolipid binding	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0043422	protein kinase B binding	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0047429	nucleoside triphosphate diphosphatase activity	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0050308	sugar-phosphatase activity	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0050815	phosphoserine residue binding	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0070739	protein-glutamic acid ligase activity	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0070740	tubulin-glutamic acid ligase activity	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:1990757	ubiquitin ligase activator activity	3/3458	10/18639	0.3	1.61703296703297	0.278948617618081	0.669777705971472
GO:0051117	ATPase binding	18/3458	84/18639	0.214285714285714	1.15502354788069	0.287929686821465	0.687730782876361
GO:0030332	cyclin binding	8/3458	34/18639	0.235294117647059	1.26826115061409	0.287971166762461	0.687730782876361
GO:0052866	phosphatidylinositol phosphate phosphatase activity	8/3458	34/18639	0.235294117647059	1.26826115061409	0.287971166762461	0.687730782876361
GO:1901681	sulfur compound binding	55/3458	275/18639	0.2	1.07802197802198	0.289426996228599	0.689973285652106
GO:0070063	RNA polymerase binding	13/3458	59/18639	0.220338983050847	1.18765133171913	0.29240151502066	0.69489192388233
GO:0015485	cholesterol binding	12/3458	54/18639	0.222222222222222	1.1978021978022	0.29261937065519	0.69489192388233
GO:0008234	cysteine-type peptidase activity	38/3458	187/18639	0.203208556149733	1.09531644825762	0.293051800109177	0.69489192388233
GO:0101005	deubiquitinase activity	24/3458	115/18639	0.208695652173913	1.12489249880554	0.295010723819237	0.696944478697487
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	4/3458	15/18639	0.266666666666667	1.43736263736264	0.298152332903783	0.696944478697487
GO:0016846	carbon-sulfur lyase activity	4/3458	15/18639	0.266666666666667	1.43736263736264	0.298152332903783	0.696944478697487
GO:0045504	dynein heavy chain binding	4/3458	15/18639	0.266666666666667	1.43736263736264	0.298152332903783	0.696944478697487
GO:0050780	dopamine receptor binding	4/3458	15/18639	0.266666666666667	1.43736263736264	0.298152332903783	0.696944478697487
GO:0120283	protein serine/threonine kinase binding	4/3458	15/18639	0.266666666666667	1.43736263736264	0.298152332903783	0.696944478697487
GO:0141050	histone H3K deacetylase activity	4/3458	15/18639	0.266666666666667	1.43736263736264	0.298152332903783	0.696944478697487
GO:0141051	histone H4K deacetylase activity	4/3458	15/18639	0.266666666666667	1.43736263736264	0.298152332903783	0.696944478697487
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	46/3458	229/18639	0.200873362445415	1.08272949757666	0.298615911471882	0.696944478697487
GO:0061608	nuclear import signal receptor activity	5/3458	20/18639	0.25	1.34752747252747	0.307972300178544	0.717527086803414
GO:0044183	protein folding chaperone	16/3458	75/18639	0.213333333333333	1.14989010989011	0.310056568127234	0.721124596602538
GO:0016782	transferase activity, transferring sulphur-containing groups	15/3458	70/18639	0.214285714285714	1.15502354788069	0.311746140607547	0.72245116720405
GO:0000030	mannosyltransferase activity	6/3458	25/18639	0.24	1.29362637362637	0.313332753416588	0.72245116720405
GO:0015645	fatty acid ligase activity	6/3458	25/18639	0.24	1.29362637362637	0.313332753416588	0.72245116720405
GO:0019211	phosphatase activator activity	6/3458	25/18639	0.24	1.29362637362637	0.313332753416588	0.72245116720405
GO:0120515	fatty acid-CoA ligase activity	6/3458	25/18639	0.24	1.29362637362637	0.313332753416588	0.72245116720405
GO:0022839	monoatomic ion-gated channel activity	7/3458	30/18639	0.233333333333333	1.25769230769231	0.316225513171096	0.724118456403795
GO:0031210	phosphatidylcholine binding	7/3458	30/18639	0.233333333333333	1.25769230769231	0.316225513171096	0.724118456403795
GO:0031624	ubiquitin conjugating enzyme binding	7/3458	30/18639	0.233333333333333	1.25769230769231	0.316225513171096	0.724118456403795
GO:0035925	mRNA 3'-UTR AU-rich region binding	7/3458	30/18639	0.233333333333333	1.25769230769231	0.316225513171096	0.724118456403795
GO:0051539	4 iron, 4 sulfur cluster binding	10/3458	45/18639	0.222222222222222	1.1978021978022	0.317798932762739	0.725778930370517
GO:0032451	demethylase activity	9/3458	40/18639	0.225	1.21277472527473	0.318037958252249	0.725778930370517
GO:0001217	DNA-binding transcription repressor activity	55/3458	278/18639	0.197841726618705	1.0663886473239	0.320258313926441	0.726346195971469
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	18/3458	86/18639	0.209302325581395	1.12816253513928	0.325350181612787	0.726346195971469
GO:0015101	organic cation transmembrane transporter activity	17/3458	81/18639	0.209876543209877	1.13125763125763	0.327810347121869	0.726346195971469
GO:0033192	calmodulin-dependent protein phosphatase activity	17/3458	81/18639	0.209876543209877	1.13125763125763	0.327810347121869	0.726346195971469
GO:0140791	histone H2AXS140 phosphatase activity	17/3458	81/18639	0.209876543209877	1.13125763125763	0.327810347121869	0.726346195971469
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	17/3458	81/18639	0.209876543209877	1.13125763125763	0.327810347121869	0.726346195971469
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	17/3458	81/18639	0.209876543209877	1.13125763125763	0.327810347121869	0.726346195971469
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	17/3458	81/18639	0.209876543209877	1.13125763125763	0.327810347121869	0.726346195971469
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	17/3458	81/18639	0.209876543209877	1.13125763125763	0.327810347121869	0.726346195971469
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	17/3458	81/18639	0.209876543209877	1.13125763125763	0.327810347121869	0.726346195971469
GO:1990439	MAP kinase serine/threonine phosphatase activity	17/3458	81/18639	0.209876543209877	1.13125763125763	0.327810347121869	0.726346195971469
GO:0051536	iron-sulfur cluster binding	16/3458	76/18639	0.210526315789474	1.13475997686524	0.33027473858809	0.726346195971469
GO:0140034	methylation-dependent protein binding	16/3458	76/18639	0.210526315789474	1.13475997686524	0.33027473858809	0.726346195971469
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0005114	type II transforming growth factor beta receptor binding	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0005225	volume-sensitive anion channel activity	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0005536	D-glucose binding	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0008526	phosphatidylinositol transfer activity	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0010854	adenylate cyclase regulator activity	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0015173	aromatic amino acid transmembrane transporter activity	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0019107	myristoyltransferase activity	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0032050	clathrin heavy chain binding	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0034056	estrogen response element binding	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0034511	U3 snoRNA binding	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0034713	type I transforming growth factor beta receptor binding	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0045294	alpha-catenin binding	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0048185	activin binding	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0140537	transcription regulator activator activity	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/3458	11/18639	0.272727272727273	1.47002997002997	0.334608921739666	0.726346195971469
GO:0015026	coreceptor activity	13/3458	61/18639	0.213114754098361	1.14871194379391	0.337586553331371	0.731620208924319
GO:0005521	lamin binding	4/3458	16/18639	0.25	1.34752747252747	0.344104775763019	0.733948050632568
GO:0008296	3'-5'-DNA exonuclease activity	4/3458	16/18639	0.25	1.34752747252747	0.344104775763019	0.733948050632568
GO:0022858	alanine transmembrane transporter activity	4/3458	16/18639	0.25	1.34752747252747	0.344104775763019	0.733948050632568
GO:0030275	LRR domain binding	4/3458	16/18639	0.25	1.34752747252747	0.344104775763019	0.733948050632568
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	4/3458	16/18639	0.25	1.34752747252747	0.344104775763019	0.733948050632568
GO:0004180	carboxypeptidase activity	10/3458	46/18639	0.217391304347826	1.17176301958911	0.344319267293435	0.733948050632568
GO:0008081	phosphoric diester hydrolase activity	18/3458	87/18639	0.206896551724138	1.11519514967791	0.344518041359693	0.733948050632568
GO:0015175	neutral L-amino acid transmembrane transporter activity	9/3458	41/18639	0.219512195121951	1.18319485392656	0.346225601318984	0.733948050632568
GO:0140318	protein transporter activity	9/3458	41/18639	0.219512195121951	1.18319485392656	0.346225601318984	0.733948050632568
GO:0070851	growth factor receptor binding	28/3458	139/18639	0.201438848920863	1.0857775318207	0.346716630939268	0.733948050632568
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	17/3458	82/18639	0.207317073170732	1.1174618064862	0.347623594307802	0.733948050632568
GO:0033549	MAP kinase phosphatase activity	17/3458	82/18639	0.207317073170732	1.1174618064862	0.347623594307802	0.733948050632568
GO:0047499	calcium-independent phospholipase A2 activity	7/3458	31/18639	0.225806451612903	1.21712158808933	0.348869768601237	0.733948050632568
GO:0005112	Notch binding	6/3458	26/18639	0.230769230769231	1.24387151310228	0.349106376143581	0.733948050632568
GO:0005160	transforming growth factor beta receptor binding	6/3458	26/18639	0.230769230769231	1.24387151310228	0.349106376143581	0.733948050632568
GO:0030247	polysaccharide binding	6/3458	26/18639	0.230769230769231	1.24387151310228	0.349106376143581	0.733948050632568
GO:0030507	spectrin binding	6/3458	26/18639	0.230769230769231	1.24387151310228	0.349106376143581	0.733948050632568
GO:0034237	protein kinase A regulatory subunit binding	6/3458	26/18639	0.230769230769231	1.24387151310228	0.349106376143581	0.733948050632568
GO:0050681	nuclear androgen receptor binding	6/3458	26/18639	0.230769230769231	1.24387151310228	0.349106376143581	0.733948050632568
GO:0042379	chemokine receptor binding	15/3458	72/18639	0.208333333333333	1.12293956043956	0.354030167760444	0.74312936157263
GO:0019842	vitamin binding	30/3458	150/18639	0.2	1.07802197802198	0.355195992541303	0.744406044022981
GO:0051213	dioxygenase activity	19/3458	93/18639	0.204301075268817	1.10120524636654	0.360286215747304	0.753890435772181
GO:0004866	endopeptidase inhibitor activity	32/3458	161/18639	0.198757763975155	1.07132618933861	0.36297919006013	0.758336805524685
GO:0004197	cysteine-type endopeptidase activity	18/3458	88/18639	0.204545454545455	1.10252247752248	0.363923595320055	0.759121874612926
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	17/3458	83/18639	0.204819277108434	1.10399841122733	0.36767545552323	0.765751533734027
GO:0019213	deacetylase activity	8/3458	37/18639	0.216216216216216	1.16542916542917	0.378326960039011	0.779760015604282
GO:0047498	calcium-dependent phospholipase A2 activity	7/3458	32/18639	0.21875	1.17908653846154	0.381841519173452	0.779760015604282
GO:0071813	lipoprotein particle binding	7/3458	32/18639	0.21875	1.17908653846154	0.381841519173452	0.779760015604282
GO:0071814	protein-lipid complex binding	7/3458	32/18639	0.21875	1.17908653846154	0.381841519173452	0.779760015604282
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	52/3458	268/18639	0.194029850746269	1.04584221748401	0.383470607839875	0.779760015604282
GO:0004364	glutathione transferase activity	6/3458	27/18639	0.222222222222222	1.1978021978022	0.385183212477282	0.779760015604282
GO:0008266	poly(U) RNA binding	6/3458	27/18639	0.222222222222222	1.1978021978022	0.385183212477282	0.779760015604282
GO:0016405	CoA-ligase activity	6/3458	27/18639	0.222222222222222	1.1978021978022	0.385183212477282	0.779760015604282
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	6/3458	27/18639	0.222222222222222	1.1978021978022	0.385183212477282	0.779760015604282
GO:0017018	myosin phosphatase activity	17/3458	84/18639	0.202380952380952	1.09085557299843	0.38790945653711	0.779760015604282
GO:0061980	regulatory RNA binding	12/3458	58/18639	0.206896551724138	1.11519514967791	0.388563305426064	0.779760015604282
GO:0004859	phospholipase inhibitor activity	3/3458	12/18639	0.25	1.34752747252747	0.39002055857552	0.779760015604282
GO:0005025	transforming growth factor beta receptor activity, type I	3/3458	12/18639	0.25	1.34752747252747	0.39002055857552	0.779760015604282
GO:0005026	transforming growth factor beta receptor activity, type II	3/3458	12/18639	0.25	1.34752747252747	0.39002055857552	0.779760015604282
GO:0005049	nuclear export signal receptor activity	3/3458	12/18639	0.25	1.34752747252747	0.39002055857552	0.779760015604282
GO:0005527	macrolide binding	3/3458	12/18639	0.25	1.34752747252747	0.39002055857552	0.779760015604282
GO:0016361	activin receptor activity, type I	3/3458	12/18639	0.25	1.34752747252747	0.39002055857552	0.779760015604282
GO:0016362	activin receptor activity, type II	3/3458	12/18639	0.25	1.34752747252747	0.39002055857552	0.779760015604282
GO:0016423	tRNA (guanine) methyltransferase activity	3/3458	12/18639	0.25	1.34752747252747	0.39002055857552	0.779760015604282
GO:0017002	activin receptor activity	3/3458	12/18639	0.25	1.34752747252747	0.39002055857552	0.779760015604282
GO:0035014	phosphatidylinositol 3-kinase regulator activity	3/3458	12/18639	0.25	1.34752747252747	0.39002055857552	0.779760015604282
GO:0035251	UDP-glucosyltransferase activity	3/3458	12/18639	0.25	1.34752747252747	0.39002055857552	0.779760015604282
GO:0035497	cAMP response element binding	3/3458	12/18639	0.25	1.34752747252747	0.39002055857552	0.779760015604282
GO:0045295	gamma-catenin binding	3/3458	12/18639	0.25	1.34752747252747	0.39002055857552	0.779760015604282
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/3458	12/18639	0.25	1.34752747252747	0.39002055857552	0.779760015604282
GO:0141221	histone deacetylase activity, hydrolytic mechanism	3/3458	12/18639	0.25	1.34752747252747	0.39002055857552	0.779760015604282
GO:0070403	NAD+ binding	4/3458	17/18639	0.235294117647059	1.26826115061409	0.390172052751805	0.779760015604282
GO:0005544	calcium-dependent phospholipid binding	11/3458	53/18639	0.207547169811321	1.11870205266432	0.393280993411105	0.784707209004256
GO:0003697	single-stranded DNA binding	24/3458	121/18639	0.198347107438017	1.06911270547634	0.393823093657567	0.784707209004256
GO:0005501	retinoid binding	8/3458	38/18639	0.210526315789474	1.13475997686524	0.408990199384855	0.81250285145652
GO:0019840	isoprenoid binding	8/3458	38/18639	0.210526315789474	1.13475997686524	0.408990199384855	0.81250285145652
GO:0004721	phosphoprotein phosphatase activity	34/3458	175/18639	0.194285714285714	1.04722135007849	0.412525129302551	0.818262405494442
GO:0070888	E-box binding	12/3458	59/18639	0.203389830508475	1.0962935369715	0.41311525191255	0.818262405494442
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	11/3458	54/18639	0.203703703703704	1.09798534798535	0.419031641092851	0.828751467939195
GO:0051959	dynein light intermediate chain binding	6/3458	28/18639	0.214285714285714	1.15502354788069	0.421247361335571	0.831901223939329
GO:0072341	modified amino acid binding	18/3458	91/18639	0.197802197802198	1.0661755826591	0.423052390038309	0.834231817874657
GO:0035254	glutamate receptor binding	10/3458	49/18639	0.204081632653061	1.10002242655304	0.425358340666568	0.837541865471783
GO:0016849	phosphorus-oxygen lyase activity	5/3458	23/18639	0.217391304347826	1.17176301958911	0.428147537907547	0.837939086345561
GO:0017134	fibroblast growth factor binding	5/3458	23/18639	0.217391304347826	1.17176301958911	0.428147537907547	0.837939086345561
GO:0031681	G-protein beta-subunit binding	5/3458	23/18639	0.217391304347826	1.17176301958911	0.428147537907547	0.837939086345561
GO:0099186	structural constituent of postsynapse	5/3458	23/18639	0.217391304347826	1.17176301958911	0.428147537907547	0.837939086345561
GO:0050660	flavin adenine dinucleotide binding	17/3458	86/18639	0.197674418604651	1.06548683874265	0.428698423950576	0.837939086345561
GO:0019205	nucleobase-containing compound kinase activity	9/3458	44/18639	0.204545454545455	1.10252247752248	0.432178544305507	0.838729316233282
GO:0051087	protein-folding chaperone binding	26/3458	134/18639	0.194029850746269	1.04584221748401	0.434390156623584	0.838729316233282
GO:0000400	four-way junction DNA binding	4/3458	18/18639	0.222222222222222	1.1978021978022	0.435735379443814	0.838729316233282
GO:0000900	mRNA regulatory element binding translation repressor activity	4/3458	18/18639	0.222222222222222	1.1978021978022	0.435735379443814	0.838729316233282
GO:0016854	racemase and epimerase activity	4/3458	18/18639	0.222222222222222	1.1978021978022	0.435735379443814	0.838729316233282
GO:0017128	phospholipid scramblase activity	4/3458	18/18639	0.222222222222222	1.1978021978022	0.435735379443814	0.838729316233282
GO:0030228	lipoprotein particle receptor activity	4/3458	18/18639	0.222222222222222	1.1978021978022	0.435735379443814	0.838729316233282
GO:0031690	adrenergic receptor binding	4/3458	18/18639	0.222222222222222	1.1978021978022	0.435735379443814	0.838729316233282
GO:0050811	GABA receptor binding	4/3458	18/18639	0.222222222222222	1.1978021978022	0.435735379443814	0.838729316233282
GO:1901611	phosphatidylglycerol binding	4/3458	18/18639	0.222222222222222	1.1978021978022	0.435735379443814	0.838729316233282
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	12/3458	60/18639	0.2	1.07802197802198	0.437696544890508	0.838729316233282
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	8/3458	39/18639	0.205128205128205	1.10566356720203	0.439605952083716	0.838729316233282
GO:0051015	actin filament binding	40/3458	209/18639	0.191387559808612	1.0315999789684	0.441253565036331	0.838729316233282
GO:0005496	steroid binding	21/3458	108/18639	0.194444444444444	1.04807692307692	0.444165443971207	0.838729316233282
GO:0002161	aminoacyl-tRNA editing activity	3/3458	13/18639	0.230769230769231	1.24387151310228	0.444180993690584	0.838729316233282
GO:0005542	folic acid binding	3/3458	13/18639	0.230769230769231	1.24387151310228	0.444180993690584	0.838729316233282
GO:0017154	semaphorin receptor activity	3/3458	13/18639	0.230769230769231	1.24387151310228	0.444180993690584	0.838729316233282
GO:0032396	inhibitory MHC class I receptor activity	3/3458	13/18639	0.230769230769231	1.24387151310228	0.444180993690584	0.838729316233282
GO:0039706	co-receptor binding	3/3458	13/18639	0.230769230769231	1.24387151310228	0.444180993690584	0.838729316233282
GO:0070123	transforming growth factor beta receptor activity, type III	3/3458	13/18639	0.230769230769231	1.24387151310228	0.444180993690584	0.838729316233282
GO:0089720	caspase binding	3/3458	13/18639	0.230769230769231	1.24387151310228	0.444180993690584	0.838729316233282
GO:0140410	monoatomic cation:bicarbonate symporter activity	3/3458	13/18639	0.230769230769231	1.24387151310228	0.444180993690584	0.838729316233282
GO:0140666	annealing activity	3/3458	13/18639	0.230769230769231	1.24387151310228	0.444180993690584	0.838729316233282
GO:0140852	histone ubiquitin ligase activity	3/3458	13/18639	0.230769230769231	1.24387151310228	0.444180993690584	0.838729316233282
GO:0016831	carboxy-lyase activity	7/3458	34/18639	0.205882352941176	1.10972850678733	0.447802106137425	0.844372615386246
GO:0004722	protein serine/threonine phosphatase activity	20/3458	103/18639	0.194174757281553	1.04662327963299	0.450064560915251	0.847441733176108
GO:0015297	antiporter activity	26/3458	135/18639	0.192592592592593	1.03809523809524	0.450796716977116	0.847624812907676
GO:0003785	actin monomer binding	6/3458	29/18639	0.206896551724138	1.11519514967791	0.457008120192998	0.856890225361871
GO:0035250	UDP-galactosyltransferase activity	6/3458	29/18639	0.206896551724138	1.11519514967791	0.457008120192998	0.856890225361871
GO:0022804	active transmembrane transporter activity	86/3458	457/18639	0.188183807439825	1.01433140163994	0.460500918839326	0.862228228121319
GO:0008237	metallopeptidase activity	35/3458	184/18639	0.190217391304348	1.02529264214047	0.46463039749942	0.868228902838745
GO:0004806	triacylglycerol lipase activity	5/3458	24/18639	0.208333333333333	1.12293956043956	0.467607925948358	0.868228902838745
GO:0005540	hyaluronic acid binding	5/3458	24/18639	0.208333333333333	1.12293956043956	0.467607925948358	0.868228902838745
GO:0030215	semaphorin receptor binding	5/3458	24/18639	0.208333333333333	1.12293956043956	0.467607925948358	0.868228902838745
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	5/3458	24/18639	0.208333333333333	1.12293956043956	0.467607925948358	0.868228902838745
GO:0070840	dynein complex binding	5/3458	24/18639	0.208333333333333	1.12293956043956	0.467607925948358	0.868228902838745
GO:0042277	peptide binding	47/3458	249/18639	0.188755020080321	1.01741030054283	0.473424468810207	0.877807869252259
GO:0008173	RNA methyltransferase activity	13/3458	67/18639	0.194029850746269	1.04584221748401	0.478049705106044	0.879649940519204
GO:0005010	insulin-like growth factor receptor activity	10/3458	51/18639	0.196078431372549	1.05688429217841	0.479307438912664	0.879649940519204
GO:0005030	neurotrophin receptor activity	10/3458	51/18639	0.196078431372549	1.05688429217841	0.479307438912664	0.879649940519204
GO:0016918	retinal binding	4/3458	19/18639	0.210526315789474	1.13475997686524	0.480269548990307	0.879649940519204
GO:0043395	heparan sulfate proteoglycan binding	4/3458	19/18639	0.210526315789474	1.13475997686524	0.480269548990307	0.879649940519204
GO:0046527	glucosyltransferase activity	4/3458	19/18639	0.210526315789474	1.13475997686524	0.480269548990307	0.879649940519204
GO:1990380	K48-linked deubiquitinase activity	4/3458	19/18639	0.210526315789474	1.13475997686524	0.480269548990307	0.879649940519204
GO:0004623	phospholipase A2 activity	7/3458	35/18639	0.2	1.07802197802198	0.480348169766666	0.879649940519204
GO:0005154	epidermal growth factor receptor binding	7/3458	35/18639	0.2	1.07802197802198	0.480348169766666	0.879649940519204
GO:0015179	L-amino acid transmembrane transporter activity	12/3458	62/18639	0.193548387096774	1.04324707550514	0.48657566214913	0.889833573930258
GO:0003727	single-stranded RNA binding	17/3458	89/18639	0.191011235955056	1.02957155204346	0.489859618255446	0.89296703243444
GO:0008187	poly-pyrimidine tract binding	6/3458	30/18639	0.2	1.07802197802198	0.492203771948473	0.89296703243444
GO:0098918	structural constituent of synapse	6/3458	30/18639	0.2	1.07802197802198	0.492203771948473	0.89296703243444
GO:0015932	nucleobase-containing compound transmembrane transporter activity	11/3458	57/18639	0.192982456140351	1.0401966454598	0.495809920324946	0.89296703243444
GO:0004065	arylsulfatase activity	3/3458	14/18639	0.214285714285714	1.15502354788069	0.496315758851202	0.89296703243444
GO:0005347	ATP transmembrane transporter activity	3/3458	14/18639	0.214285714285714	1.15502354788069	0.496315758851202	0.89296703243444
GO:0008494	translation activator activity	3/3458	14/18639	0.214285714285714	1.15502354788069	0.496315758851202	0.89296703243444
GO:0015386	potassium:proton antiporter activity	3/3458	14/18639	0.214285714285714	1.15502354788069	0.496315758851202	0.89296703243444
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	3/3458	14/18639	0.214285714285714	1.15502354788069	0.496315758851202	0.89296703243444
GO:0042043	neurexin family protein binding	3/3458	14/18639	0.214285714285714	1.15502354788069	0.496315758851202	0.89296703243444
GO:0061665	SUMO ligase activity	3/3458	14/18639	0.214285714285714	1.15502354788069	0.496315758851202	0.89296703243444
GO:0098821	BMP receptor activity	3/3458	14/18639	0.214285714285714	1.15502354788069	0.496315758851202	0.89296703243444
GO:0001530	lipopolysaccharide binding	8/3458	41/18639	0.195121951219512	1.05172875904583	0.50000336853494	0.898390978457799
GO:0140223	general transcription initiation factor activity	13/3458	68/18639	0.191176470588235	1.03046218487395	0.501289945488264	0.899492039283377
GO:0001848	complement binding	5/3458	25/18639	0.2	1.07802197802198	0.5061767190813	0.900994559964714
GO:0003707	nuclear steroid receptor activity	5/3458	25/18639	0.2	1.07802197802198	0.5061767190813	0.900994559964714
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	5/3458	25/18639	0.2	1.07802197802198	0.5061767190813	0.900994559964714
GO:0017056	structural constituent of nuclear pore	5/3458	25/18639	0.2	1.07802197802198	0.5061767190813	0.900994559964714
GO:0042974	nuclear retinoic acid receptor binding	5/3458	25/18639	0.2	1.07802197802198	0.5061767190813	0.900994559964714
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	5/3458	25/18639	0.2	1.07802197802198	0.5061767190813	0.900994559964714
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	7/3458	36/18639	0.194444444444444	1.04807692307692	0.512341600130338	0.908334709394425
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	7/3458	36/18639	0.194444444444444	1.04807692307692	0.512341600130338	0.908334709394425
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	7/3458	36/18639	0.194444444444444	1.04807692307692	0.512341600130338	0.908334709394425
GO:0035064	methylated histone binding	14/3458	74/18639	0.189189189189189	1.01975051975052	0.514793734443164	0.911471665094992
GO:0000339	RNA cap binding	4/3458	20/18639	0.2	1.07802197802198	0.523343861193248	0.92293798506339
GO:0010851	cyclase regulator activity	4/3458	20/18639	0.2	1.07802197802198	0.523343861193248	0.92293798506339
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	4/3458	20/18639	0.2	1.07802197802198	0.523343861193248	0.92293798506339
GO:0051879	Hsp90 protein binding	8/3458	42/18639	0.19047619047619	1.02668759811617	0.529474287201555	0.932517379174243
GO:0008146	sulfotransferase activity	10/3458	53/18639	0.188679245283019	1.01700186605847	0.532086543820885	0.932985429813541
GO:1901505	carbohydrate derivative transmembrane transporter activity	10/3458	53/18639	0.188679245283019	1.01700186605847	0.532086543820885	0.932985429813541
GO:0005319	lipid transporter activity	33/3458	178/18639	0.185393258426966	0.99929003580689	0.532487700575549	0.932985429813541
GO:0008238	exopeptidase activity	19/3458	102/18639	0.186274509803922	1.00404007756949	0.53253550375874	0.932985429813541
GO:0004843	cysteine-type deubiquitinase activity	20/3458	108/18639	0.185185185185185	0.998168498168498	0.542843828641318	0.942544289689344
GO:0004529	DNA exonuclease activity	5/3458	26/18639	0.192307692307692	1.0365595942519	0.543574419780756	0.942544289689344
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/3458	26/18639	0.192307692307692	1.0365595942519	0.543574419780756	0.942544289689344
GO:0008157	protein phosphatase 1 binding	5/3458	26/18639	0.192307692307692	1.0365595942519	0.543574419780756	0.942544289689344
GO:0070412	R-SMAD binding	5/3458	26/18639	0.192307692307692	1.0365595942519	0.543574419780756	0.942544289689344
GO:0140693	molecular condensate scaffold activity	9/3458	48/18639	0.1875	1.0106456043956	0.544444013528607	0.942544289689344
GO:0005041	low-density lipoprotein particle receptor activity	3/3458	15/18639	0.2	1.07802197802198	0.545856615338056	0.942544289689344
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/3458	15/18639	0.2	1.07802197802198	0.545856615338056	0.942544289689344
GO:0017081	chloride channel regulator activity	3/3458	15/18639	0.2	1.07802197802198	0.545856615338056	0.942544289689344
GO:0030553	cGMP binding	3/3458	15/18639	0.2	1.07802197802198	0.545856615338056	0.942544289689344
GO:0046982	protein heterodimerization activity	68/3458	369/18639	0.184281842818428	0.993299383543286	0.546257489246985	0.942544289689344
GO:0016798	hydrolase activity, acting on glycosyl bonds	24/3458	130/18639	0.184615384615385	0.995097210481826	0.546463880314271	0.942544289689344
GO:0016779	nucleotidyltransferase activity	25/3458	136/18639	0.183823529411765	0.990829023917259	0.55541362085296	0.949360960273928
GO:0008378	galactosyltransferase activity	6/3458	32/18639	0.1875	1.0106456043956	0.560010643577584	0.949360960273928
GO:0030515	snoRNA binding	6/3458	32/18639	0.1875	1.0106456043956	0.560010643577584	0.949360960273928
GO:0008373	sialyltransferase activity	4/3458	21/18639	0.19047619047619	1.02668759811617	0.564618709754495	0.949360960273928
GO:0061891	calcium ion sensor activity	4/3458	21/18639	0.19047619047619	1.02668759811617	0.564618709754495	0.949360960273928
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	11/3458	60/18639	0.183333333333333	0.988186813186813	0.569839386628823	0.949360960273928
GO:0005004	GPI-linked ephrin receptor activity	9/3458	49/18639	0.183673469387755	0.990020183897735	0.571238289922566	0.949360960273928
GO:0005008	hepatocyte growth factor receptor activity	9/3458	49/18639	0.183673469387755	0.990020183897735	0.571238289922566	0.949360960273928
GO:0005009	insulin receptor activity	9/3458	49/18639	0.183673469387755	0.990020183897735	0.571238289922566	0.949360960273928
GO:0005011	macrophage colony-stimulating factor receptor activity	9/3458	49/18639	0.183673469387755	0.990020183897735	0.571238289922566	0.949360960273928
GO:0005018	platelet-derived growth factor alpha-receptor activity	9/3458	49/18639	0.183673469387755	0.990020183897735	0.571238289922566	0.949360960273928
GO:0005020	stem cell factor receptor activity	9/3458	49/18639	0.183673469387755	0.990020183897735	0.571238289922566	0.949360960273928
GO:0008288	boss receptor activity	9/3458	49/18639	0.183673469387755	0.990020183897735	0.571238289922566	0.949360960273928
GO:0036332	placental growth factor receptor activity	9/3458	49/18639	0.183673469387755	0.990020183897735	0.571238289922566	0.949360960273928
GO:0038062	protein tyrosine kinase collagen receptor activity	9/3458	49/18639	0.183673469387755	0.990020183897735	0.571238289922566	0.949360960273928
GO:0060175	brain-derived neurotrophic factor receptor activity	9/3458	49/18639	0.183673469387755	0.990020183897735	0.571238289922566	0.949360960273928
GO:0000182	rDNA binding	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0005031	tumor necrosis factor receptor activity	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0005345	purine nucleobase transmembrane transporter activity	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0015187	glycine transmembrane transporter activity	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0015203	polyamine transmembrane transporter activity	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0015279	store-operated calcium channel activity	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0016303	1-phosphatidylinositol-3-kinase activity	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0031956	medium-chain fatty acid-CoA ligase activity	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0032356	oxidized DNA binding	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0035374	chondroitin sulfate binding	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0043121	neurotrophin binding	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0070097	delta-catenin binding	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0099122	RNA polymerase II C-terminal domain binding	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0140999	histone H3K4 trimethyltransferase activity	2/3458	10/18639	0.2	1.07802197802198	0.578976339111421	0.949360960273928
GO:0001671	ATPase activator activity	5/3458	27/18639	0.185185185185185	0.998168498168498	0.579572421440637	0.949360960273928
GO:0023026	MHC class II protein complex binding	5/3458	27/18639	0.185185185185185	0.998168498168498	0.579572421440637	0.949360960273928
GO:0008235	metalloexopeptidase activity	12/3458	66/18639	0.181818181818182	0.98001998001998	0.580868356801812	0.9503177160912
GO:0001664	G protein-coupled receptor binding	54/3458	297/18639	0.181818181818182	0.98001998001998	0.589539856024088	0.96213341537432
GO:0005024	transforming growth factor beta receptor activity	3/3458	16/18639	0.1875	1.0106456043956	0.592414732163065	0.96213341537432
GO:0015562	efflux transmembrane transporter activity	3/3458	16/18639	0.1875	1.0106456043956	0.592414732163065	0.96213341537432
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/3458	16/18639	0.1875	1.0106456043956	0.592414732163065	0.96213341537432
GO:0019841	retinol binding	3/3458	16/18639	0.1875	1.0106456043956	0.592414732163065	0.96213341537432
GO:0055102	lipase inhibitor activity	3/3458	16/18639	0.1875	1.0106456043956	0.592414732163065	0.96213341537432
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	22/3458	122/18639	0.180327868852459	0.971987029364079	0.595630979953167	0.964234181241633
GO:0005006	epidermal growth factor receptor activity	9/3458	50/18639	0.18	0.97021978021978	0.597319601413356	0.964234181241633
GO:0005007	fibroblast growth factor receptor activity	9/3458	50/18639	0.18	0.97021978021978	0.597319601413356	0.964234181241633
GO:0005017	platelet-derived growth factor receptor activity	9/3458	50/18639	0.18	0.97021978021978	0.597319601413356	0.964234181241633
GO:0005019	platelet-derived growth factor beta-receptor activity	9/3458	50/18639	0.18	0.97021978021978	0.597319601413356	0.964234181241633
GO:0000217	DNA secondary structure binding	7/3458	39/18639	0.179487179487179	0.967455621301775	0.603410985788821	0.968900640870022
GO:0008093	cytoskeletal anchor activity	4/3458	22/18639	0.181818181818182	0.98001998001998	0.603839200901767	0.968900640870022
GO:0008649	rRNA methyltransferase activity	4/3458	22/18639	0.181818181818182	0.98001998001998	0.603839200901767	0.968900640870022
GO:0046972	histone H4K16 acetyltransferase activity	4/3458	22/18639	0.181818181818182	0.98001998001998	0.603839200901767	0.968900640870022
GO:0140784	metal ion sensor activity	4/3458	22/18639	0.181818181818182	0.98001998001998	0.603839200901767	0.968900640870022
GO:0008009	chemokine activity	8/3458	45/18639	0.177777777777778	0.958241758241758	0.61344200331475	0.979304502443306
GO:0005200	structural constituent of cytoskeleton	20/3458	112/18639	0.178571428571429	0.962519623233909	0.613494148806809	0.979304502443306
GO:0019789	SUMO transferase activity	5/3458	28/18639	0.178571428571429	0.962519623233909	0.613990912767826	0.979304502443306
GO:0051537	2 iron, 2 sulfur cluster binding	5/3458	28/18639	0.178571428571429	0.962519623233909	0.613990912767826	0.979304502443306
GO:0141052	histone H3 demethylase activity	5/3458	28/18639	0.178571428571429	0.962519623233909	0.613990912767826	0.979304502443306
GO:0005125	cytokine activity	42/3458	234/18639	0.179487179487179	0.967455621301775	0.620960028467072	0.981190196132929
GO:0005021	vascular endothelial growth factor receptor activity	9/3458	51/18639	0.176470588235294	0.951195862960569	0.622607921949219	0.981190196132929
GO:0030544	Hsp70 protein binding	9/3458	51/18639	0.176470588235294	0.951195862960569	0.622607921949219	0.981190196132929
GO:0140662	ATP-dependent protein folding chaperone	7/3458	40/18639	0.175	0.943269230769231	0.631710720538236	0.981190196132929
GO:0003684	damaged DNA binding	13/3458	74/18639	0.175675675675676	0.946911196911197	0.633187186885012	0.981190196132929
GO:0001851	complement component C3b binding	2/3458	11/18639	0.181818181818182	0.98001998001998	0.633280209638478	0.981190196132929
GO:0004016	adenylate cyclase activity	2/3458	11/18639	0.181818181818182	0.98001998001998	0.633280209638478	0.981190196132929
GO:0015205	nucleobase transmembrane transporter activity	2/3458	11/18639	0.181818181818182	0.98001998001998	0.633280209638478	0.981190196132929
GO:0015217	ADP transmembrane transporter activity	2/3458	11/18639	0.181818181818182	0.98001998001998	0.633280209638478	0.981190196132929
GO:0016176	superoxide-generating NADPH oxidase activator activity	2/3458	11/18639	0.181818181818182	0.98001998001998	0.633280209638478	0.981190196132929
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/3458	11/18639	0.181818181818182	0.98001998001998	0.633280209638478	0.981190196132929
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/3458	11/18639	0.181818181818182	0.98001998001998	0.633280209638478	0.981190196132929
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/3458	11/18639	0.181818181818182	0.98001998001998	0.633280209638478	0.981190196132929
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/3458	11/18639	0.181818181818182	0.98001998001998	0.633280209638478	0.981190196132929
GO:0019215	intermediate filament binding	2/3458	11/18639	0.181818181818182	0.98001998001998	0.633280209638478	0.981190196132929
GO:0019864	IgG binding	2/3458	11/18639	0.181818181818182	0.98001998001998	0.633280209638478	0.981190196132929
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/3458	11/18639	0.181818181818182	0.98001998001998	0.633280209638478	0.981190196132929
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/3458	11/18639	0.181818181818182	0.98001998001998	0.633280209638478	0.981190196132929
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/3458	11/18639	0.181818181818182	0.98001998001998	0.633280209638478	0.981190196132929
GO:0140031	phosphorylation-dependent protein binding	2/3458	11/18639	0.181818181818182	0.98001998001998	0.633280209638478	0.981190196132929
GO:0005092	GDP-dissociation inhibitor activity	3/3458	17/18639	0.176470588235294	0.951195862960569	0.635752449179763	0.981190196132929
GO:0008484	sulfuric ester hydrolase activity	3/3458	17/18639	0.176470588235294	0.951195862960569	0.635752449179763	0.981190196132929
GO:0016018	cyclosporin A binding	3/3458	17/18639	0.176470588235294	0.951195862960569	0.635752449179763	0.981190196132929
GO:0017110	nucleoside diphosphate phosphatase activity	3/3458	17/18639	0.176470588235294	0.951195862960569	0.635752449179763	0.981190196132929
GO:0038191	neuropilin binding	3/3458	17/18639	0.176470588235294	0.951195862960569	0.635752449179763	0.981190196132929
GO:0045236	CXCR chemokine receptor binding	3/3458	17/18639	0.176470588235294	0.951195862960569	0.635752449179763	0.981190196132929
GO:0070492	oligosaccharide binding	3/3458	17/18639	0.176470588235294	0.951195862960569	0.635752449179763	0.981190196132929
GO:1990226	histone methyltransferase binding	3/3458	17/18639	0.176470588235294	0.951195862960569	0.635752449179763	0.981190196132929
GO:1901682	sulfur compound transmembrane transporter activity	11/3458	63/18639	0.174603174603175	0.941130298273155	0.638981510286569	0.984469433181663
GO:0003887	DNA-directed DNA polymerase activity	4/3458	23/18639	0.173913043478261	0.937410415671285	0.640826919426866	0.984469433181663
GO:0070577	lysine-acetylated histone binding	4/3458	23/18639	0.173913043478261	0.937410415671285	0.640826919426866	0.984469433181663
GO:0140102	catalytic activity, acting on a rRNA	4/3458	23/18639	0.173913043478261	0.937410415671285	0.640826919426866	0.984469433181663
GO:0003774	cytoskeletal motor activity	27/3458	153/18639	0.176470588235294	0.951195862960569	0.646210368613704	0.991598669079649
GO:0016229	steroid dehydrogenase activity	6/3458	35/18639	0.171428571428571	0.924018838304553	0.652771628192434	1
GO:0008170	N-methyltransferase activity	17/3458	98/18639	0.173469387755102	0.935019062570083	0.661127471876834	1
GO:0140938	histone H3 methyltransferase activity	8/3458	47/18639	0.170212765957447	0.917465513210194	0.664765847451333	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	23/3458	132/18639	0.174242424242424	0.939185814185814	0.665645447065459	1
GO:0004540	RNA nuclease activity	21/3458	121/18639	0.173553719008264	0.935473617291799	0.669095154632951	1
GO:0005003	ephrin receptor activity	9/3458	53/18639	0.169811320754717	0.915301679452623	0.670548181061143	1
GO:0005005	transmembrane-ephrin receptor activity	9/3458	53/18639	0.169811320754717	0.915301679452623	0.670548181061143	1
GO:0038064	collagen receptor activity	9/3458	53/18639	0.169811320754717	0.915301679452623	0.670548181061143	1
GO:0098631	cell adhesion mediator activity	13/3458	76/18639	0.171052631578947	0.921992481203007	0.673007455538997	1
GO:0004622	lysophospholipase activity	4/3458	24/18639	0.166666666666667	0.898351648351648	0.675470718122567	1
GO:0043998	histone H2A acetyltransferase activity	4/3458	24/18639	0.166666666666667	0.898351648351648	0.675470718122567	1
GO:0140033	acetylation-dependent protein binding	4/3458	24/18639	0.166666666666667	0.898351648351648	0.675470718122567	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	3/3458	18/18639	0.166666666666667	0.898351648351648	0.675755863126952	1
GO:0008308	voltage-gated monoatomic anion channel activity	3/3458	18/18639	0.166666666666667	0.898351648351648	0.675755863126952	1
GO:0008409	5'-3' exonuclease activity	3/3458	18/18639	0.166666666666667	0.898351648351648	0.675755863126952	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/3458	18/18639	0.166666666666667	0.898351648351648	0.675755863126952	1
GO:0034185	apolipoprotein binding	3/3458	18/18639	0.166666666666667	0.898351648351648	0.675755863126952	1
GO:0099602	neurotransmitter receptor regulator activity	3/3458	18/18639	0.166666666666667	0.898351648351648	0.675755863126952	1
GO:0032452	histone demethylase activity	5/3458	30/18639	0.166666666666667	0.898351648351648	0.677594039075403	1
GO:0033612	receptor serine/threonine kinase binding	5/3458	30/18639	0.166666666666667	0.898351648351648	0.677594039075403	1
GO:0045505	dynein intermediate chain binding	6/3458	36/18639	0.166666666666667	0.898351648351648	0.680857633804853	1
GO:0038024	cargo receptor activity	11/3458	65/18639	0.169230769230769	0.912172442941674	0.681596305634553	1
GO:0000995	RNA polymerase III general transcription initiation factor activity	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:0004000	adenosine deaminase activity	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:0015368	calcium:monoatomic cation antiporter activity	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:0016273	arginine N-methyltransferase activity	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:0016274	protein-arginine N-methyltransferase activity	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:0016801	hydrolase activity, acting on ether bonds	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:0016803	ether hydrolase activity	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:0017166	vinculin binding	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:0034452	dynactin binding	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:0070679	inositol 1,4,5 trisphosphate binding	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:0097677	STAT family protein binding	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:0140900	chloride:bicarbonate antiporter activity	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:1990817	poly(A) RNA polymerase activity	2/3458	12/18639	0.166666666666667	0.898351648351648	0.68193213985107	1
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	29/3458	167/18639	0.173652694610778	0.936007106665789	0.684584400750655	1
GO:0035198	miRNA binding	7/3458	42/18639	0.166666666666667	0.898351648351648	0.68469747064168	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	10/3458	60/18639	0.166666666666667	0.898351648351648	0.697423147029206	1
GO:0008276	protein methyltransferase activity	16/3458	95/18639	0.168421052631579	0.907807981492192	0.706362602093552	1
GO:0008327	methyl-CpG binding	5/3458	31/18639	0.161290322580645	0.86937256292095	0.706630597983787	1
GO:0017147	Wnt-protein binding	5/3458	31/18639	0.161290322580645	0.86937256292095	0.706630597983787	1
GO:0140457	protein demethylase activity	5/3458	31/18639	0.161290322580645	0.86937256292095	0.706630597983787	1
GO:0022829	wide pore channel activity	6/3458	37/18639	0.162162162162162	0.874071874071874	0.70742136625386	1
GO:0005251	delayed rectifier potassium channel activity	4/3458	25/18639	0.16	0.862417582417582	0.707717194130428	1
GO:0008139	nuclear localization sequence binding	4/3458	25/18639	0.16	0.862417582417582	0.707717194130428	1
GO:0015662	P-type ion transporter activity	4/3458	25/18639	0.16	0.862417582417582	0.707717194130428	1
GO:0120020	cholesterol transfer activity	4/3458	25/18639	0.16	0.862417582417582	0.707717194130428	1
GO:0140358	P-type transmembrane transporter activity	4/3458	25/18639	0.16	0.862417582417582	0.707717194130428	1
GO:0008375	acetylglucosaminyltransferase activity	7/3458	43/18639	0.162790697674419	0.877459749552773	0.709278903063111	1
GO:0019199	transmembrane receptor protein kinase activity	13/3458	78/18639	0.166666666666667	0.898351648351648	0.71025496002191	1
GO:0016763	pentosyltransferase activity	8/3458	49/18639	0.163265306122449	0.880017941242431	0.71177497995555	1
GO:0060590	ATPase regulator activity	8/3458	49/18639	0.163265306122449	0.880017941242431	0.71177497995555	1
GO:0005229	intracellularly calcium-gated chloride channel activity	3/3458	19/18639	0.157894736842105	0.85106998264893	0.712409547027573	1
GO:0008301	DNA binding, bending	3/3458	19/18639	0.157894736842105	0.85106998264893	0.712409547027573	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/3458	19/18639	0.157894736842105	0.85106998264893	0.712409547027573	1
GO:0022821	solute:potassium antiporter activity	3/3458	19/18639	0.157894736842105	0.85106998264893	0.712409547027573	1
GO:0030506	ankyrin binding	3/3458	19/18639	0.157894736842105	0.85106998264893	0.712409547027573	1
GO:0042800	histone H3K4 methyltransferase activity	3/3458	19/18639	0.157894736842105	0.85106998264893	0.712409547027573	1
GO:0141147	intracellularly calcium-gated channel activity	3/3458	19/18639	0.157894736842105	0.85106998264893	0.712409547027573	1
GO:0098632	cell-cell adhesion mediator activity	9/3458	55/18639	0.163636363636364	0.882017982017982	0.71466408503553	1
GO:0016407	acetyltransferase activity	16/3458	96/18639	0.166666666666667	0.898351648351648	0.722517752250432	1
GO:0005035	death receptor activity	2/3458	13/18639	0.153846153846154	0.829247675401522	0.725159620971158	1
GO:0005172	vascular endothelial growth factor receptor binding	2/3458	13/18639	0.153846153846154	0.829247675401522	0.725159620971158	1
GO:0005338	nucleotide-sugar transmembrane transporter activity	2/3458	13/18639	0.153846153846154	0.829247675401522	0.725159620971158	1
GO:0019104	DNA N-glycosylase activity	2/3458	13/18639	0.153846153846154	0.829247675401522	0.725159620971158	1
GO:0030955	potassium ion binding	2/3458	13/18639	0.153846153846154	0.829247675401522	0.725159620971158	1
GO:0043560	insulin receptor substrate binding	2/3458	13/18639	0.153846153846154	0.829247675401522	0.725159620971158	1
GO:0045159	myosin II binding	2/3458	13/18639	0.153846153846154	0.829247675401522	0.725159620971158	1
GO:0046974	histone H3K9 methyltransferase activity	2/3458	13/18639	0.153846153846154	0.829247675401522	0.725159620971158	1
GO:0061459	L-arginine transmembrane transporter activity	2/3458	13/18639	0.153846153846154	0.829247675401522	0.725159620971158	1
GO:0031072	heat shock protein binding	22/3458	131/18639	0.16793893129771	0.905209294522272	0.731717959781214	1
GO:0005109	frizzled binding	6/3458	38/18639	0.157894736842105	0.85106998264893	0.732435981994592	1
GO:0015106	bicarbonate transmembrane transporter activity	5/3458	32/18639	0.15625	0.84220467032967	0.733782441392342	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	5/3458	32/18639	0.15625	0.84220467032967	0.733782441392342	1
GO:0042910	xenobiotic transmembrane transporter activity	5/3458	32/18639	0.15625	0.84220467032967	0.733782441392342	1
GO:0070717	poly-purine tract binding	5/3458	32/18639	0.15625	0.84220467032967	0.733782441392342	1
GO:0120015	sterol transfer activity	5/3458	32/18639	0.15625	0.84220467032967	0.733782441392342	1
GO:0004435	phosphatidylinositol phospholipase C activity	4/3458	26/18639	0.153846153846154	0.829247675401522	0.737561334921277	1
GO:0050750	low-density lipoprotein particle receptor binding	4/3458	26/18639	0.153846153846154	0.829247675401522	0.737561334921277	1
GO:0001972	retinoic acid binding	3/3458	20/18639	0.15	0.808516483516484	0.745774079821866	1
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	3/3458	20/18639	0.15	0.808516483516484	0.745774079821866	1
GO:0031418	L-ascorbic acid binding	3/3458	20/18639	0.15	0.808516483516484	0.745774079821866	1
GO:0043024	ribosomal small subunit binding	3/3458	20/18639	0.15	0.808516483516484	0.745774079821866	1
GO:0030527	structural constituent of chromatin	16/3458	98/18639	0.163265306122449	0.880017941242431	0.753131590210642	1
GO:0016597	amino acid binding	8/3458	51/18639	0.156862745098039	0.845507433742728	0.754221229089183	1
GO:0002039	p53 binding	11/3458	69/18639	0.159420289855072	0.859292881032011	0.757262422251846	1
GO:0008174	mRNA methyltransferase activity	2/3458	14/18639	0.142857142857143	0.770015698587127	0.763300264657817	1
GO:0008331	high voltage-gated calcium channel activity	2/3458	14/18639	0.142857142857143	0.770015698587127	0.763300264657817	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	2/3458	14/18639	0.142857142857143	0.770015698587127	0.763300264657817	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/3458	14/18639	0.142857142857143	0.770015698587127	0.763300264657817	1
GO:0031404	chloride ion binding	2/3458	14/18639	0.142857142857143	0.770015698587127	0.763300264657817	1
GO:0032454	histone H3K9 demethylase activity	2/3458	14/18639	0.142857142857143	0.770015698587127	0.763300264657817	1
GO:0042813	Wnt receptor activity	2/3458	14/18639	0.142857142857143	0.770015698587127	0.763300264657817	1
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/3458	14/18639	0.142857142857143	0.770015698587127	0.763300264657817	1
GO:1901612	cardiolipin binding	2/3458	14/18639	0.142857142857143	0.770015698587127	0.763300264657817	1
GO:1990825	sequence-specific mRNA binding	2/3458	14/18639	0.142857142857143	0.770015698587127	0.763300264657817	1
GO:0005385	zinc ion transmembrane transporter activity	4/3458	27/18639	0.148148148148148	0.798534798534798	0.765037667700519	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/3458	27/18639	0.148148148148148	0.798534798534798	0.765037667700519	1
GO:0005539	glycosaminoglycan binding	41/3458	242/18639	0.169421487603306	0.913200435927709	0.765437667201342	1
GO:0005123	death receptor binding	3/3458	21/18639	0.142857142857143	0.770015698587127	0.775966641499761	1
GO:0009975	cyclase activity	3/3458	21/18639	0.142857142857143	0.770015698587127	0.775966641499761	1
GO:0016410	N-acyltransferase activity	15/3458	94/18639	0.159574468085106	0.860123918634557	0.779635568939277	1
GO:0008168	methyltransferase activity	34/3458	204/18639	0.166666666666667	0.898351648351648	0.782359307635141	1
GO:0015085	calcium ion transmembrane transporter activity	24/3458	147/18639	0.163265306122449	0.880017941242431	0.786904076116853	1
GO:0016866	intramolecular transferase activity	4/3458	28/18639	0.142857142857143	0.770015698587127	0.790212126855968	1
GO:0016860	intramolecular oxidoreductase activity	8/3458	53/18639	0.150943396226415	0.813601492846776	0.792049271084666	1
GO:0004867	serine-type endopeptidase inhibitor activity	15/3458	95/18639	0.157894736842105	0.85106998264893	0.793374250222851	1
GO:0000774	adenyl-nucleotide exchange factor activity	2/3458	15/18639	0.133333333333333	0.718681318681319	0.796753133783934	1
GO:0004089	carbonate dehydratase activity	2/3458	15/18639	0.133333333333333	0.718681318681319	0.796753133783934	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	2/3458	15/18639	0.133333333333333	0.718681318681319	0.796753133783934	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/3458	15/18639	0.133333333333333	0.718681318681319	0.796753133783934	1
GO:0031005	filamin binding	2/3458	15/18639	0.133333333333333	0.718681318681319	0.796753133783934	1
GO:0048531	beta-1,3-galactosyltransferase activity	2/3458	15/18639	0.133333333333333	0.718681318681319	0.796753133783934	1
GO:0140161	monocarboxylate:sodium symporter activity	2/3458	15/18639	0.133333333333333	0.718681318681319	0.796753133783934	1
GO:0140776	protein-containing complex destabilizing activity	2/3458	15/18639	0.133333333333333	0.718681318681319	0.796753133783934	1
GO:0015377	chloride:monoatomic cation symporter activity	3/3458	22/18639	0.136363636363636	0.735014985014985	0.803144658436287	1
GO:0032931	histone H3K56 acetyltransferase activity	3/3458	22/18639	0.136363636363636	0.735014985014985	0.803144658436287	1
GO:0034062	5'-3' RNA polymerase activity	3/3458	22/18639	0.136363636363636	0.735014985014985	0.803144658436287	1
GO:0043992	histone H3K9 acetyltransferase activity	3/3458	22/18639	0.136363636363636	0.735014985014985	0.803144658436287	1
GO:0043993	histone H3K18 acetyltransferase activity	3/3458	22/18639	0.136363636363636	0.735014985014985	0.803144658436287	1
GO:0043994	histone H3K23 acetyltransferase activity	3/3458	22/18639	0.136363636363636	0.735014985014985	0.803144658436287	1
GO:0043999	histone H2AK5 acetyltransferase activity	3/3458	22/18639	0.136363636363636	0.735014985014985	0.803144658436287	1
GO:0044012	histone H2AK9 acetyltransferase activity	3/3458	22/18639	0.136363636363636	0.735014985014985	0.803144658436287	1
GO:0044014	histone H2BK5 acetyltransferase activity	3/3458	22/18639	0.136363636363636	0.735014985014985	0.803144658436287	1
GO:0044015	histone H2BK12 acetyltransferase activity	3/3458	22/18639	0.136363636363636	0.735014985014985	0.803144658436287	1
GO:0044016	histone H3K4 acetyltransferase activity	3/3458	22/18639	0.136363636363636	0.735014985014985	0.803144658436287	1
GO:0044017	histone H3K27 acetyltransferase activity	3/3458	22/18639	0.136363636363636	0.735014985014985	0.803144658436287	1
GO:0044018	histone H3K36 acetyltransferase activity	3/3458	22/18639	0.136363636363636	0.735014985014985	0.803144658436287	1
GO:0097747	RNA polymerase activity	3/3458	22/18639	0.136363636363636	0.735014985014985	0.803144658436287	1
GO:0140908	histone H3K122 acetyltransferase activity	3/3458	22/18639	0.136363636363636	0.735014985014985	0.803144658436287	1
GO:0010485	histone H4 acetyltransferase activity	5/3458	35/18639	0.142857142857143	0.770015698587127	0.804092812210228	1
GO:0034061	DNA polymerase activity	5/3458	35/18639	0.142857142857143	0.770015698587127	0.804092812210228	1
GO:0015171	amino acid transmembrane transporter activity	16/3458	102/18639	0.156862745098039	0.845507433742728	0.807418441508059	1
GO:0004181	metallocarboxypeptidase activity	4/3458	29/18639	0.137931034482759	0.743463433118605	0.813174761357576	1
GO:0004629	phospholipase C activity	4/3458	29/18639	0.137931034482759	0.743463433118605	0.813174761357576	1
GO:0099604	ligand-gated calcium channel activity	4/3458	29/18639	0.137931034482759	0.743463433118605	0.813174761357576	1
GO:0004402	histone acetyltransferase activity	6/3458	42/18639	0.142857142857143	0.770015698587127	0.817125309211019	1
GO:0008307	structural constituent of muscle	6/3458	42/18639	0.142857142857143	0.770015698587127	0.817125309211019	1
GO:0004620	phospholipase activity	17/3458	109/18639	0.155963302752294	0.840659340659341	0.820260980089399	1
GO:0140767	enzyme-substrate adaptor activity	22/3458	139/18639	0.158273381294964	0.853110917859119	0.825596739998395	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/3458	16/18639	0.125	0.673763736263736	0.825944334015487	1
GO:0005159	insulin-like growth factor receptor binding	2/3458	16/18639	0.125	0.673763736263736	0.825944334015487	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	2/3458	16/18639	0.125	0.673763736263736	0.825944334015487	1
GO:0015378	sodium:chloride symporter activity	2/3458	16/18639	0.125	0.673763736263736	0.825944334015487	1
GO:0015923	mannosidase activity	2/3458	16/18639	0.125	0.673763736263736	0.825944334015487	1
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/3458	16/18639	0.125	0.673763736263736	0.825944334015487	1
GO:0016853	isomerase activity	29/3458	180/18639	0.161111111111111	0.868406593406593	0.826704954361742	1
GO:0005212	structural constituent of eye lens	3/3458	23/18639	0.130434782608696	0.703057811753464	0.8274923192877	1
GO:0005283	amino acid:sodium symporter activity	3/3458	23/18639	0.130434782608696	0.703057811753464	0.8274923192877	1
GO:0008171	O-methyltransferase activity	3/3458	23/18639	0.130434782608696	0.703057811753464	0.8274923192877	1
GO:0044013	histone H2B acetyltransferase activity	3/3458	23/18639	0.130434782608696	0.703057811753464	0.8274923192877	1
GO:0042626	ATPase-coupled transmembrane transporter activity	15/3458	98/18639	0.153061224489796	0.825016819914779	0.83091022583436	1
GO:0004222	metalloendopeptidase activity	17/3458	110/18639	0.154545454545455	0.833016983016983	0.831490194852587	1
GO:0043995	histone H4K5 acetyltransferase activity	4/3458	30/18639	0.133333333333333	0.718681318681319	0.834033334016372	1
GO:0043996	histone H4K8 acetyltransferase activity	4/3458	30/18639	0.133333333333333	0.718681318681319	0.834033334016372	1
GO:0043997	histone H4K12 acetyltransferase activity	4/3458	30/18639	0.133333333333333	0.718681318681319	0.834033334016372	1
GO:0005245	voltage-gated calcium channel activity	6/3458	43/18639	0.13953488372093	0.752108356759519	0.834613915613382	1
GO:0030145	manganese ion binding	10/3458	68/18639	0.147058823529412	0.792663219133807	0.834779533519637	1
GO:0030170	pyridoxal phosphate binding	8/3458	56/18639	0.142857142857143	0.770015698587127	0.840382696547245	1
GO:0070001	aspartic-type peptidase activity	5/3458	37/18639	0.135135135135135	0.728393228393228	0.842180092581429	1
GO:0048020	CCR chemokine receptor binding	7/3458	50/18639	0.14	0.754615384615385	0.844782634694141	1
GO:0016279	protein-lysine N-methyltransferase activity	10/3458	69/18639	0.144927536231884	0.781175346392738	0.847918026954856	1
GO:0005315	phosphate transmembrane transporter activity	3/3458	24/18639	0.125	0.673763736263736	0.849209690882719	1
GO:0015295	solute:proton symporter activity	3/3458	24/18639	0.125	0.673763736263736	0.849209690882719	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/3458	24/18639	0.125	0.673763736263736	0.849209690882719	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/3458	17/18639	0.117647058823529	0.634130575307046	0.851303251993584	1
GO:0004550	nucleoside diphosphate kinase activity	2/3458	17/18639	0.117647058823529	0.634130575307046	0.851303251993584	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/3458	17/18639	0.117647058823529	0.634130575307046	0.851303251993584	1
GO:0008569	minus-end-directed microtubule motor activity	2/3458	17/18639	0.117647058823529	0.634130575307046	0.851303251993584	1
GO:0009881	photoreceptor activity	2/3458	17/18639	0.117647058823529	0.634130575307046	0.851303251993584	1
GO:0015278	intracellularly gated calcium channel activity	2/3458	17/18639	0.117647058823529	0.634130575307046	0.851303251993584	1
GO:0019198	transmembrane receptor protein phosphatase activity	2/3458	17/18639	0.117647058823529	0.634130575307046	0.851303251993584	1
GO:0030548	acetylcholine receptor regulator activity	2/3458	17/18639	0.117647058823529	0.634130575307046	0.851303251993584	1
GO:0032183	SUMO binding	2/3458	17/18639	0.117647058823529	0.634130575307046	0.851303251993584	1
GO:0008013	beta-catenin binding	16/3458	106/18639	0.150943396226415	0.813601492846776	0.852546031971854	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/3458	31/18639	0.129032258064516	0.69549805033676	0.852907813428607	1
GO:0005452	solute:inorganic anion antiporter activity	4/3458	31/18639	0.129032258064516	0.69549805033676	0.852907813428607	1
GO:0070325	lipoprotein particle receptor binding	4/3458	31/18639	0.129032258064516	0.69549805033676	0.852907813428607	1
GO:0070279	vitamin B6 binding	8/3458	57/18639	0.140350877192982	0.756506651243493	0.85436537641263	1
GO:0000146	microfilament motor activity	5/3458	38/18639	0.131578947368421	0.709224985540775	0.858807988124889	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	10/3458	70/18639	0.142857142857143	0.770015698587127	0.860221868763498	1
GO:0016278	lysine N-methyltransferase activity	10/3458	70/18639	0.142857142857143	0.770015698587127	0.860221868763498	1
GO:0005262	calcium channel activity	20/3458	131/18639	0.152671755725191	0.822917540474792	0.861892233521745	1
GO:0004536	DNA nuclease activity	9/3458	64/18639	0.140625	0.757984203296703	0.863339410839855	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	3/3458	25/18639	0.12	0.646813186813187	0.868504122258031	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/3458	25/18639	0.12	0.646813186813187	0.868504122258031	1
GO:0019706	protein-cysteine S-palmitoyltransferase activity	3/3458	25/18639	0.12	0.646813186813187	0.868504122258031	1
GO:0019707	protein-cysteine S-acyltransferase activity	3/3458	25/18639	0.12	0.646813186813187	0.868504122258031	1
GO:0043425	bHLH transcription factor binding	4/3458	32/18639	0.125	0.673763736263736	0.869925723719502	1
GO:0004518	nuclease activity	33/3458	209/18639	0.157894736842105	0.85106998264893	0.870469806077134	1
GO:0016741	transferase activity, transferring one-carbon groups	34/3458	215/18639	0.158139534883721	0.852389470994122	0.871410165927248	1
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0003796	lysozyme activity	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0005131	growth hormone receptor binding	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0005522	profilin binding	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0008190	eukaryotic initiation factor 4E binding	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0008401	retinoic acid 4-hydroxylase activity	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0015643	toxic substance binding	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0016783	sulfurtransferase activity	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0019531	oxalate transmembrane transporter activity	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0031419	cobalamin binding	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0032052	bile acid binding	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0045322	unmethylated CpG binding	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0051864	histone H3K36 demethylase activity	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0051880	G-quadruplex DNA binding	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:1990763	arrestin family protein binding	1/3458	10/18639	0.1	0.539010989010989	0.871607754803796	1
GO:0140299	molecular sensor activity	10/3458	71/18639	0.140845070422535	0.759170407057731	0.871719303178863	1
GO:0008083	growth factor activity	25/3458	162/18639	0.154320987654321	0.831807081807082	0.871737012262217	1
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/3458	18/18639	0.111111111111111	0.598901098901099	0.873246675601913	1
GO:0015373	monoatomic anion:sodium symporter activity	2/3458	18/18639	0.111111111111111	0.598901098901099	0.873246675601913	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/3458	18/18639	0.111111111111111	0.598901098901099	0.873246675601913	1
GO:0035615	clathrin adaptor activity	2/3458	18/18639	0.111111111111111	0.598901098901099	0.873246675601913	1
GO:0070628	proteasome binding	2/3458	18/18639	0.111111111111111	0.598901098901099	0.873246675601913	1
GO:0016776	phosphotransferase activity, phosphate group as acceptor	5/3458	39/18639	0.128205128205128	0.691039729501268	0.873942240464752	1
GO:0015291	secondary active transmembrane transporter activity	46/3458	287/18639	0.160278745644599	0.863920052073362	0.883477382228304	1
GO:0034212	protein N-acetyltransferase activity	7/3458	53/18639	0.132075471698113	0.711901306240929	0.884727662910403	1
GO:0140416	transcription regulator inhibitor activity	4/3458	33/18639	0.121212121212121	0.653346653346653	0.885218293680035	1
GO:0070006	metalloaminopeptidase activity	3/3458	26/18639	0.115384615384615	0.621935756551141	0.885583616258477	1
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	18/3458	122/18639	0.147540983606557	0.795262114934246	0.887368480463596	1
GO:0004177	aminopeptidase activity	5/3458	40/18639	0.125	0.673763736263736	0.887675423702054	1
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	5/3458	40/18639	0.125	0.673763736263736	0.887675423702054	1
GO:0061733	protein-lysine-acetyltransferase activity	6/3458	47/18639	0.127659574468085	0.688099134907646	0.891496108377769	1
GO:0003756	protein disulfide isomerase activity	2/3458	19/18639	0.105263157894737	0.56737998843262	0.892168690728306	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/3458	19/18639	0.105263157894737	0.56737998843262	0.892168690728306	1
GO:0015245	fatty acid transmembrane transporter activity	2/3458	19/18639	0.105263157894737	0.56737998843262	0.892168690728306	1
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/3458	19/18639	0.105263157894737	0.56737998843262	0.892168690728306	1
GO:0022840	leak channel activity	2/3458	19/18639	0.105263157894737	0.56737998843262	0.892168690728306	1
GO:0022842	narrow pore channel activity	2/3458	19/18639	0.105263157894737	0.56737998843262	0.892168690728306	1
GO:0031420	alkali metal ion binding	2/3458	19/18639	0.105263157894737	0.56737998843262	0.892168690728306	1
GO:0050145	nucleoside monophosphate kinase activity	2/3458	19/18639	0.105263157894737	0.56737998843262	0.892168690728306	1
GO:0004175	endopeptidase activity	66/3458	405/18639	0.162962962962963	0.878388278388278	0.894990202759272	1
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0008046	axon guidance receptor activity	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0008199	ferric iron binding	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0008271	secondary active sulfate transmembrane transporter activity	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0008503	benzodiazepine receptor activity	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0032794	GTPase activating protein binding	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0043522	leucine zipper domain binding	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0070697	activin receptor binding	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0180030	inositol phosphate kinase activity	1/3458	11/18639	0.0909090909090909	0.49000999000999	0.895440509320328	1
GO:0016500	protein-hormone receptor activity	9/3458	67/18639	0.134328358208955	0.724044612104314	0.896160081732851	1
GO:0042054	histone methyltransferase activity	9/3458	67/18639	0.134328358208955	0.724044612104314	0.896160081732851	1
GO:0005044	scavenger receptor activity	3/3458	27/18639	0.111111111111111	0.598901098901099	0.900651859828222	1
GO:0016298	lipase activity	19/3458	130/18639	0.146153846153846	0.787785291631446	0.901374590194347	1
GO:0042562	hormone binding	13/3458	94/18639	0.138297872340426	0.745440729483283	0.909663665996542	1
GO:0005343	organic acid:sodium symporter activity	4/3458	35/18639	0.114285714285714	0.616012558869702	0.911152754822515	1
GO:0004520	DNA endonuclease activity	5/3458	42/18639	0.119047619047619	0.641679748822606	0.911314597732523	1
GO:0042056	chemoattractant activity	5/3458	42/18639	0.119047619047619	0.641679748822606	0.911314597732523	1
GO:0036408	histone H3K14 acetyltransferase activity	3/3458	28/18639	0.107142857142857	0.577511773940345	0.913904627784892	1
GO:0008080	N-acetyltransferase activity	9/3458	69/18639	0.130434782608696	0.703057811753464	0.914163994593733	1
GO:0003720	telomerase activity	1/3458	12/18639	0.0833333333333333	0.449175824175824	0.914850361090261	1
GO:0005165	neurotrophin receptor binding	1/3458	12/18639	0.0833333333333333	0.449175824175824	0.914850361090261	1
GO:0008179	adenylate cyclase binding	1/3458	12/18639	0.0833333333333333	0.449175824175824	0.914850361090261	1
GO:0008504	monoamine transmembrane transporter activity	1/3458	12/18639	0.0833333333333333	0.449175824175824	0.914850361090261	1
GO:0010853	cyclase activator activity	1/3458	12/18639	0.0833333333333333	0.449175824175824	0.914850361090261	1
GO:0015132	prostaglandin transmembrane transporter activity	1/3458	12/18639	0.0833333333333333	0.449175824175824	0.914850361090261	1
GO:0015166	polyol transmembrane transporter activity	1/3458	12/18639	0.0833333333333333	0.449175824175824	0.914850361090261	1
GO:0031543	peptidyl-proline dioxygenase activity	1/3458	12/18639	0.0833333333333333	0.449175824175824	0.914850361090261	1
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/3458	12/18639	0.0833333333333333	0.449175824175824	0.914850361090261	1
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/3458	12/18639	0.0833333333333333	0.449175824175824	0.914850361090261	1
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/3458	12/18639	0.0833333333333333	0.449175824175824	0.914850361090261	1
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/3458	12/18639	0.0833333333333333	0.449175824175824	0.914850361090261	1
GO:0004190	aspartic-type endopeptidase activity	4/3458	36/18639	0.111111111111111	0.598901098901099	0.922050667439265	1
GO:0016409	palmitoyltransferase activity	4/3458	36/18639	0.111111111111111	0.598901098901099	0.922050667439265	1
GO:0015174	basic amino acid transmembrane transporter activity	2/3458	21/18639	0.0952380952380952	0.513343799058085	0.922378770933856	1
GO:0140312	cargo adaptor activity	2/3458	21/18639	0.0952380952380952	0.513343799058085	0.922378770933856	1
GO:1904047	S-adenosyl-L-methionine binding	2/3458	21/18639	0.0952380952380952	0.513343799058085	0.922378770933856	1
GO:0005416	amino acid:monoatomic cation symporter activity	3/3458	29/18639	0.103448275862069	0.557597574838954	0.925527304680352	1
GO:0010484	histone H3 acetyltransferase activity	3/3458	29/18639	0.103448275862069	0.557597574838954	0.925527304680352	1
GO:0016417	S-acyltransferase activity	3/3458	29/18639	0.103448275862069	0.557597574838954	0.925527304680352	1
GO:0140104	molecular carrier activity	38/3458	249/18639	0.152610441767068	0.822587051502714	0.926039871641714	1
GO:0016757	glycosyltransferase activity	41/3458	267/18639	0.153558052434457	0.827694777132979	0.926745376687454	1
GO:0003964	RNA-directed DNA polymerase activity	1/3458	13/18639	0.0769230769230769	0.414623837700761	0.930657922766853	1
GO:0004993	G protein-coupled serotonin receptor activity	1/3458	13/18639	0.0769230769230769	0.414623837700761	0.930657922766853	1
GO:0008035	high-density lipoprotein particle binding	1/3458	13/18639	0.0769230769230769	0.414623837700761	0.930657922766853	1
GO:0008417	fucosyltransferase activity	1/3458	13/18639	0.0769230769230769	0.414623837700761	0.930657922766853	1
GO:0009982	pseudouridine synthase activity	1/3458	13/18639	0.0769230769230769	0.414623837700761	0.930657922766853	1
GO:0031432	titin binding	1/3458	13/18639	0.0769230769230769	0.414623837700761	0.930657922766853	1
GO:0035673	oligopeptide transmembrane transporter activity	1/3458	13/18639	0.0769230769230769	0.414623837700761	0.930657922766853	1
GO:0046975	histone H3K36 methyltransferase activity	1/3458	13/18639	0.0769230769230769	0.414623837700761	0.930657922766853	1
GO:0051011	microtubule minus-end binding	1/3458	13/18639	0.0769230769230769	0.414623837700761	0.930657922766853	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/3458	13/18639	0.0769230769230769	0.414623837700761	0.930657922766853	1
GO:0071714	icosanoid transmembrane transporter activity	1/3458	13/18639	0.0769230769230769	0.414623837700761	0.930657922766853	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/3458	13/18639	0.0769230769230769	0.414623837700761	0.930657922766853	1
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/3458	13/18639	0.0769230769230769	0.414623837700761	0.930657922766853	1
GO:1901338	catecholamine binding	1/3458	13/18639	0.0769230769230769	0.414623837700761	0.930657922766853	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	12/3458	91/18639	0.131868131868132	0.710783721772733	0.932426042871885	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	3/3458	30/18639	0.1	0.539010989010989	0.935693301420794	1
GO:0048019	receptor antagonist activity	3/3458	30/18639	0.1	0.539010989010989	0.935693301420794	1
GO:0042605	peptide antigen binding	5/3458	45/18639	0.111111111111111	0.598901098901099	0.938584278233611	1
GO:0005267	potassium channel activity	17/3458	124/18639	0.137096774193548	0.738966678482808	0.938779424322457	1
GO:0005344	oxygen carrier activity	1/3458	14/18639	0.0714285714285714	0.385007849293564	0.94353158877524	1
GO:0008392	arachidonate epoxygenase activity	1/3458	14/18639	0.0714285714285714	0.385007849293564	0.94353158877524	1
GO:0008559	ABC-type xenobiotic transporter activity	1/3458	14/18639	0.0714285714285714	0.385007849293564	0.94353158877524	1
GO:0015926	glucosidase activity	1/3458	14/18639	0.0714285714285714	0.385007849293564	0.94353158877524	1
GO:0043176	amine binding	1/3458	14/18639	0.0714285714285714	0.385007849293564	0.94353158877524	1
GO:0061783	peptidoglycan muralytic activity	1/3458	14/18639	0.0714285714285714	0.385007849293564	0.94353158877524	1
GO:1901474	azole transmembrane transporter activity	1/3458	14/18639	0.0714285714285714	0.385007849293564	0.94353158877524	1
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	2/3458	23/18639	0.0869565217391304	0.468705207835643	0.944474550078461	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/3458	23/18639	0.0869565217391304	0.468705207835643	0.944474550078461	1
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	2/3458	23/18639	0.0869565217391304	0.468705207835643	0.944474550078461	1
GO:0017046	peptide hormone binding	6/3458	53/18639	0.113207547169811	0.610201119635082	0.945246463124757	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	5/3458	46/18639	0.108695652173913	0.585881509794553	0.945838185538219	1
GO:0046943	carboxylic acid transmembrane transporter activity	27/3458	188/18639	0.143617021276596	0.774111526771101	0.946708416845744	1
GO:0005342	organic acid transmembrane transporter activity	27/3458	189/18639	0.142857142857143	0.770015698587127	0.950184402766653	1
GO:0017069	snRNA binding	6/3458	54/18639	0.111111111111111	0.598901098901099	0.951406284512119	1
GO:0015293	symporter activity	20/3458	146/18639	0.136986301369863	0.738371217823273	0.951990087314244	1
GO:0008514	organic anion transmembrane transporter activity	40/3458	269/18639	0.148698884758364	0.80150332938437	0.953057166412005	1
GO:0015149	hexose transmembrane transporter activity	2/3458	24/18639	0.0833333333333333	0.449175824175824	0.953134991823529	1
GO:0055056	D-glucose transmembrane transporter activity	2/3458	24/18639	0.0833333333333333	0.449175824175824	0.953134991823529	1
GO:0004559	alpha-mannosidase activity	1/3458	15/18639	0.0666666666666667	0.359340659340659	0.954015764131762	1
GO:0008020	G protein-coupled photoreceptor activity	1/3458	15/18639	0.0666666666666667	0.359340659340659	0.954015764131762	1
GO:0008242	omega peptidase activity	1/3458	15/18639	0.0666666666666667	0.359340659340659	0.954015764131762	1
GO:0015116	sulfate transmembrane transporter activity	1/3458	15/18639	0.0666666666666667	0.359340659340659	0.954015764131762	1
GO:0015250	water channel activity	1/3458	15/18639	0.0666666666666667	0.359340659340659	0.954015764131762	1
GO:0015929	hexosaminidase activity	1/3458	15/18639	0.0666666666666667	0.359340659340659	0.954015764131762	1
GO:0033130	acetylcholine receptor binding	1/3458	15/18639	0.0666666666666667	0.359340659340659	0.954015764131762	1
GO:0034483	heparan sulfate sulfotransferase activity	1/3458	15/18639	0.0666666666666667	0.359340659340659	0.954015764131762	1
GO:0047372	monoacylglycerol lipase activity	1/3458	15/18639	0.0666666666666667	0.359340659340659	0.954015764131762	1
GO:0015144	carbohydrate transmembrane transporter activity	4/3458	40/18639	0.1	0.539010989010989	0.954587471991377	1
GO:0008201	heparin binding	24/3458	172/18639	0.13953488372093	0.752108356759519	0.9553480715734	1
GO:0016758	hexosyltransferase activity	28/3458	197/18639	0.142131979695431	0.766106989457243	0.956039045962639	1
GO:0017171	serine hydrolase activity	28/3458	198/18639	0.141414141414141	0.762237762237762	0.958943166202537	1
GO:0005253	monoatomic anion channel activity	13/3458	103/18639	0.12621359223301	0.680305131761442	0.959039068976829	1
GO:0015271	outward rectifier potassium channel activity	2/3458	25/18639	0.08	0.431208791208791	0.960494197872702	1
GO:0008509	monoatomic anion transmembrane transporter activity	20/3458	149/18639	0.134228187919463	0.723504683236227	0.962017488660765	1
GO:0003688	DNA replication origin binding	1/3458	16/18639	0.0625	0.336881868131868	0.962553859472847	1
GO:0008391	arachidonate monooxygenase activity	1/3458	16/18639	0.0625	0.336881868131868	0.962553859472847	1
GO:0017070	U6 snRNA binding	1/3458	16/18639	0.0625	0.336881868131868	0.962553859472847	1
GO:0022841	potassium ion leak channel activity	1/3458	16/18639	0.0625	0.336881868131868	0.962553859472847	1
GO:0008236	serine-type peptidase activity	27/3458	194/18639	0.139175257731959	0.750169933159624	0.964802524452672	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	3/3458	34/18639	0.0882352941176471	0.475597931480284	0.964804460609611	1
GO:0008143	poly(A) binding	2/3458	26/18639	0.0769230769230769	0.414623837700761	0.966736746340555	1
GO:0015145	monosaccharide transmembrane transporter activity	2/3458	26/18639	0.0769230769230769	0.414623837700761	0.966736746340555	1
GO:0004549	tRNA-specific ribonuclease activity	1/3458	17/18639	0.0588235294117647	0.317065287653523	0.969507022440301	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/3458	17/18639	0.0588235294117647	0.317065287653523	0.969507022440301	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	4/3458	43/18639	0.0930232558139535	0.501405571173013	0.970190979735138	1
GO:0004521	RNA endonuclease activity	8/3458	73/18639	0.10958904109589	0.590696974258618	0.972569045730539	1
GO:0036002	pre-mRNA binding	6/3458	59/18639	0.101694915254237	0.548146768485752	0.973781736043523	1
GO:0015079	potassium ion transmembrane transporter activity	21/3458	160/18639	0.13125	0.707451923076923	0.973790484531847	1
GO:0030547	signaling receptor inhibitor activity	4/3458	44/18639	0.0909090909090909	0.49000999000999	0.974163286464307	1
GO:0004033	aldo-keto reductase (NADPH) activity	3/3458	36/18639	0.0833333333333333	0.449175824175824	0.974178275353322	1
GO:0004970	glutamate-gated receptor activity	1/3458	18/18639	0.0555555555555556	0.299450549450549	0.975169395783736	1
GO:0005372	water transmembrane transporter activity	1/3458	18/18639	0.0555555555555556	0.299450549450549	0.975169395783736	1
GO:0015280	ligand-gated sodium channel activity	1/3458	18/18639	0.0555555555555556	0.299450549450549	0.975169395783736	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	5/3458	52/18639	0.0961538461538462	0.518279797125951	0.975274216594064	1
GO:0008527	taste receptor activity	2/3458	28/18639	0.0714285714285714	0.385007849293564	0.976494222605899	1
GO:0051119	sugar transmembrane transporter activity	2/3458	28/18639	0.0714285714285714	0.385007849293564	0.976494222605899	1
GO:0030280	structural constituent of skin epidermis	3/3458	37/18639	0.0810810810810811	0.437035937035937	0.977923539422126	1
GO:0003777	microtubule motor activity	7/3458	68/18639	0.102941176470588	0.554864253393665	0.978763545361987	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/3458	19/18639	0.0526315789473684	0.28368999421631	0.979780546064593	1
GO:0099589	serotonin receptor activity	1/3458	19/18639	0.0526315789473684	0.28368999421631	0.979780546064593	1
GO:0106222	lncRNA binding	2/3458	29/18639	0.0689655172413793	0.371731716559303	0.980269549859643	1
GO:0061749	forked DNA-dependent helicase activity	4/3458	47/18639	0.0851063829787234	0.458732756605097	0.983300308491489	1
GO:0140359	ABC-type transporter activity	4/3458	47/18639	0.0851063829787234	0.458732756605097	0.983300308491489	1
GO:1990518	single-stranded 3'-5' DNA helicase activity	4/3458	47/18639	0.0851063829787234	0.458732756605097	0.983300308491489	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/3458	30/18639	0.0666666666666667	0.359340659340659	0.983453567605275	1
GO:0016769	transferase activity, transferring nitrogenous groups	2/3458	30/18639	0.0666666666666667	0.359340659340659	0.983453567605275	1
GO:0046873	metal ion transmembrane transporter activity	67/3458	450/18639	0.148888888888889	0.802527472527472	0.983464306603556	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/3458	20/18639	0.05	0.269505494505494	0.98353558750974	1
GO:0005326	neurotransmitter transmembrane transporter activity	1/3458	20/18639	0.05	0.269505494505494	0.98353558750974	1
GO:0140664	ATP-dependent DNA damage sensor activity	1/3458	20/18639	0.05	0.269505494505494	0.98353558750974	1
GO:0140939	histone H4 methyltransferase activity	1/3458	20/18639	0.05	0.269505494505494	0.98353558750974	1
GO:0008188	neuropeptide receptor activity	4/3458	48/18639	0.0833333333333333	0.449175824175824	0.985594400921613	1
GO:0009378	four-way junction helicase activity	4/3458	48/18639	0.0833333333333333	0.449175824175824	0.985594400921613	1
GO:0036121	double-stranded DNA helicase activity	4/3458	48/18639	0.0833333333333333	0.449175824175824	0.985594400921613	1
GO:0043138	3'-5' DNA helicase activity	4/3458	48/18639	0.0833333333333333	0.449175824175824	0.985594400921613	1
GO:0170055	lipid transmembrane transporter activity	5/3458	56/18639	0.0892857142857143	0.481259811616955	0.985705993199625	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	23/3458	181/18639	0.12707182320442	0.684931091008439	0.986572366834893	1
GO:0015125	bile acid transmembrane transporter activity	1/3458	21/18639	0.0476190476190476	0.256671899529042	0.986593428338534	1
GO:0036122	BMP binding	1/3458	21/18639	0.0476190476190476	0.256671899529042	0.986593428338534	1
GO:0070182	DNA polymerase binding	1/3458	21/18639	0.0476190476190476	0.256671899529042	0.986593428338534	1
GO:0004252	serine-type endopeptidase activity	22/3458	176/18639	0.125	0.673763736263736	0.988209176468475	1
GO:0022843	voltage-gated monoatomic cation channel activity	17/3458	143/18639	0.118881118881119	0.640782294628448	0.988365709870069	1
GO:0042923	neuropeptide binding	2/3458	33/18639	0.0606060606060606	0.326673326673327	0.990289294815312	1
GO:0008194	UDP-glycosyltransferase activity	17/3458	145/18639	0.117241379310345	0.631943918150815	0.990392965507799	1
GO:0005244	voltage-gated monoatomic ion channel activity	21/3458	173/18639	0.121387283236994	0.654290795909293	0.991417984188324	1
GO:0008376	acetylgalactosaminyltransferase activity	2/3458	34/18639	0.0588235294117647	0.317065287653523	0.991882096953169	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/3458	34/18639	0.0588235294117647	0.317065287653523	0.991882096953169	1
GO:0005249	voltage-gated potassium channel activity	10/3458	98/18639	0.102040816326531	0.550011213276519	0.992045950395235	1
GO:0004519	endonuclease activity	14/3458	127/18639	0.110236220472441	0.594185342216838	0.992584651120253	1
GO:0140597	protein carrier chaperone	23/3458	188/18639	0.122340425531915	0.659428337619827	0.992658858805731	1
GO:0140612	DNA damage sensor activity	1/3458	24/18639	0.0416666666666667	0.224587912087912	0.992762304697514	1
GO:0022832	voltage-gated channel activity	21/3458	175/18639	0.12	0.646813186813187	0.992844783123856	1
GO:0020037	heme binding	16/3458	142/18639	0.112676056338028	0.607336325646185	0.993416009452808	1
GO:0008528	G protein-coupled peptide receptor activity	13/3458	122/18639	0.10655737704918	0.574355971896956	0.994027531158034	1
GO:0008483	transaminase activity	1/3458	25/18639	0.04	0.215604395604396	0.994106809148548	1
GO:0015294	solute:monoatomic cation symporter activity	12/3458	116/18639	0.103448275862069	0.557597574838954	0.994729507998684	1
GO:0015370	solute:sodium symporter activity	7/3458	79/18639	0.0886075949367089	0.477604673807205	0.99480774369202	1
GO:0046906	tetrapyrrole binding	17/3458	152/18639	0.111842105263158	0.602841237709659	0.995193314422563	1
GO:0008066	glutamate receptor activity	1/3458	26/18639	0.0384615384615385	0.20731191885038	0.995201611660868	1
GO:0099095	ligand-gated monoatomic anion channel activity	3/3458	47/18639	0.0638297872340425	0.344049567453823	0.995645248132841	1
GO:0042887	amide transmembrane transporter activity	2/3458	38/18639	0.0526315789473684	0.28368999421631	0.996061254647841	1
GO:0005104	fibroblast growth factor receptor binding	1/3458	27/18639	0.037037037037037	0.1996336996337	0.996093076060842	1
GO:0035255	ionotropic glutamate receptor binding	1/3458	27/18639	0.037037037037037	0.1996336996337	0.996093076060842	1
GO:0005242	inward rectifier potassium channel activity	1/3458	28/18639	0.0357142857142857	0.192503924646782	0.996818959522136	1
GO:0017116	single-stranded DNA helicase activity	4/3458	58/18639	0.0689655172413793	0.371731716559303	0.996885720139186	1
GO:0005261	monoatomic cation channel activity	45/3458	341/18639	0.131964809384164	0.71130482420805	0.996909849587549	1
GO:0001653	peptide receptor activity	13/3458	128/18639	0.1015625	0.547433035714286	0.996940447322359	1
GO:0005254	chloride channel activity	7/3458	83/18639	0.0843373493975904	0.454587581093605	0.996973212412429	1
GO:0015108	chloride transmembrane transporter activity	12/3458	121/18639	0.0991735537190083	0.534556352738171	0.997032497790918	1
GO:0003678	DNA helicase activity	5/3458	74/18639	0.0675675675675676	0.364196614196614	0.998995402910693	1
GO:0015020	glucuronosyltransferase activity	1/3458	34/18639	0.0294117647058824	0.158532643826761	0.999073462964486	1
GO:0019825	oxygen binding	1/3458	34/18639	0.0294117647058824	0.158532643826761	0.999073462964486	1
GO:0051427	hormone receptor binding	1/3458	34/18639	0.0294117647058824	0.158532643826761	0.999073462964486	1
GO:0090482	vitamin transmembrane transporter activity	1/3458	34/18639	0.0294117647058824	0.158532643826761	0.999073462964486	1
GO:0003724	RNA helicase activity	5/3458	77/18639	0.0649350649350649	0.350007135721421	0.999369885753449	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/3458	36/18639	0.0277777777777778	0.149725274725275	0.999385882665408	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	64/3458	484/18639	0.132231404958678	0.712741803650895	0.999393091737216	1
GO:0015081	sodium ion transmembrane transporter activity	16/3458	164/18639	0.0975609756097561	0.525864379522916	0.999394258501246	1
GO:0140713	histone chaperone activity	16/3458	164/18639	0.0975609756097561	0.525864379522916	0.999394258501246	1
GO:0015103	inorganic anion transmembrane transporter activity	16/3458	165/18639	0.096969696969697	0.522677322677323	0.999460233800802	1
GO:0099094	ligand-gated monoatomic cation channel activity	12/3458	136/18639	0.0882352941176471	0.475597931480284	0.999521713410534	1
GO:0016887	ATP hydrolysis activity	53/3458	417/18639	0.127098321342926	0.685073918886868	0.999525981993267	1
GO:0008186	ATP-dependent activity, acting on RNA	5/3458	79/18639	0.0632911392405063	0.341146195576575	0.999539719003895	1
GO:0140674	ATP-dependent histone chaperone activity	14/3458	152/18639	0.0921052631578947	0.496457489878542	0.999567117123924	1
GO:0001216	DNA-binding transcription activator activity	64/3458	491/18639	0.130346232179226	0.702580515207806	0.999634860987059	1
GO:0005272	sodium channel activity	2/3458	51/18639	0.0392156862745098	0.211376858435682	0.999644972562714	1
GO:0005506	iron ion binding	14/3458	154/18639	0.0909090909090909	0.49000999000999	0.999660744897824	1
GO:0005216	monoatomic ion channel activity	57/3458	448/18639	0.127232142857143	0.68579523155416	0.999683063337955	1
GO:0071855	neuropeptide receptor binding	1/3458	40/18639	0.025	0.134752747252747	0.999730248085257	1
GO:0008227	G protein-coupled amine receptor activity	1/3458	41/18639	0.024390243902439	0.131466094880729	0.99978040143335	1
GO:0140658	ATP-dependent chromatin remodeler activity	14/3458	158/18639	0.0886075949367089	0.477604673807205	0.999792962765227	1
GO:0000510	H3-H4 histone complex chaperone activity	13/3458	151/18639	0.0860927152317881	0.464049195837275	0.999810316624552	1
GO:0140584	chromatin extrusion motor activity	13/3458	151/18639	0.0860927152317881	0.464049195837275	0.999810316624552	1
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	13/3458	151/18639	0.0860927152317881	0.464049195837275	0.999810316624552	1
GO:0140849	ATP-dependent H2AZ histone chaperone activity	13/3458	151/18639	0.0860927152317881	0.464049195837275	0.999810316624552	1
GO:0015616	DNA translocase activity	13/3458	152/18639	0.0855263157894737	0.460996240601504	0.999833061901589	1
GO:0061775	cohesin loader activity	13/3458	153/18639	0.0849673202614379	0.457983193277311	0.999853154954427	1
GO:0140097	catalytic activity, acting on DNA	38/3458	336/18639	0.113095238095238	0.609595761381476	0.999900857508083	1
GO:0005179	hormone activity	10/3458	132/18639	0.0757575757575758	0.408341658341658	0.999900909759667	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/3458	46/18639	0.0217391304347826	0.117176301958911	0.999921499158031	1
GO:0003689	DNA clamp loader activity	13/3458	160/18639	0.08125	0.437946428571429	0.999940982917187	1
GO:0003730	mRNA 3'-UTR binding	26/3458	262/18639	0.099236641221374	0.534896401308615	0.999964255222155	1
GO:0004497	monooxygenase activity	6/3458	106/18639	0.0566037735849057	0.305100559817541	0.999973143572655	1
GO:0003823	antigen binding	14/3458	174/18639	0.0804597701149425	0.43368700265252	0.999973459634732	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/3458	53/18639	0.0188679245283019	0.101700186605847	0.999981413701582	1
GO:0008094	ATP-dependent activity, acting on DNA	18/3458	210/18639	0.0857142857142857	0.462009419152276	0.999985438337533	1
GO:0004386	helicase activity	11/3458	155/18639	0.0709677419354839	0.382523927685218	0.999987516513206	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/3458	56/18639	0.0178571428571429	0.0962519623233909	0.999989977786975	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	2/3458	73/18639	0.0273972602739726	0.147674243564655	0.999994651317596	1
GO:0015276	ligand-gated monoatomic ion channel activity	14/3458	186/18639	0.0752688172043011	0.405707196029777	0.99999471784723	1
GO:0022836	gated channel activity	31/3458	318/18639	0.0974842767295598	0.525450964130209	0.999995946733303	1
GO:0022834	ligand-gated channel activity	14/3458	188/18639	0.074468085106383	0.40139116202946	0.999995986112877	1
GO:0022824	transmitter-gated monoatomic ion channel activity	1/3458	63/18639	0.0158730158730159	0.0855572998430141	0.99999762912701	1
GO:0022835	transmitter-gated channel activity	1/3458	63/18639	0.0158730158730159	0.0855572998430141	0.99999762912701	1
GO:0098960	postsynaptic neurotransmitter receptor activity	1/3458	69/18639	0.0144927536231884	0.0781175346392738	0.999999311219429	1
GO:0030594	neurotransmitter receptor activity	3/3458	97/18639	0.0309278350515464	0.166704429591028	0.999999426979351	1
GO:0045182	translation regulator activity	16/3458	356/18639	0.0449438202247191	0.242252129892579	1	1
GO:0030371	translation repressor activity	6/3458	329/18639	0.0182370820668693	0.0982998764153779	1	1