ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 117/3692 175/18639 0.668571428571429 3.37527162977867 6.39898474641982e-42 8.24189235338873e-39 GO:0043021 ribonucleoprotein complex binding 82/3692 177/18639 0.463276836158192 2.33884532750611 1.16751518893253e-15 7.51879781672547e-13 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 42/3692 68/18639 0.617647058823529 3.11818080428271 4.23245386392683e-14 1.81713352557925e-11 GO:0045296 cadherin binding 122/3692 334/18639 0.365269461077844 1.8440567402573 5.79650341078056e-13 1.5654672897905e-10 GO:0140101 catalytic activity, acting on a tRNA 65/3692 139/18639 0.467625899280576 2.36080149964535 6.07712457216809e-13 1.5654672897905e-10 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 35/3692 58/18639 0.603448275862069 3.04649848694288 1.45465974157591e-11 3.12266957858295e-09 GO:0008137 NADH dehydrogenase (ubiquinone) activity 28/3692 41/18639 0.682926829268293 3.4477446291256 2.15474477406083e-11 3.96473038427193e-09 GO:0003954 NADH dehydrogenase activity 29/3692 44/18639 0.659090909090909 3.32740938638826 3.62263332938018e-11 5.83243966030209e-09 GO:0009055 electron transfer activity 54/3692 116/18639 0.46551724137931 2.35015597564165 6.67314447399661e-11 9.55001120278625e-09 GO:0019843 rRNA binding 36/3692 65/18639 0.553846153846154 2.79608300691724 2.28486406499203e-10 2.94290491570973e-08 GO:0015078 proton transmembrane transporter activity 72/3692 185/18639 0.389189189189189 1.96481508594185 1.35656828600751e-09 1.58841813852516e-07 GO:0043022 ribosome binding 50/3692 112/18639 0.446428571428571 2.25378714595264 2.03543307212813e-09 2.18469816408419e-07 GO:0140098 catalytic activity, acting on RNA 124/3692 387/18639 0.320413436692506 1.6176018544181 6.13276916632776e-09 6.07615898940781e-07 GO:0098641 cadherin binding involved in cell-cell adhesion 15/3692 18/18639 0.833333333333333 4.20706933911159 1.22441829171652e-08 1.12646482837919e-06 GO:0022853 active monoatomic ion transmembrane transporter activity 50/3692 118/18639 0.423728813559322 2.13918779954827 1.71587698566571e-08 1.47336637169162e-06 GO:0000049 tRNA binding 38/3692 80/18639 0.475 2.39802952329361 2.17881802826597e-08 1.75394851275411e-06 GO:0004812 aminoacyl-tRNA ligase activity 24/3692 41/18639 0.585365853658537 2.95520968210766 5.43835636132507e-08 3.81212540952916e-06 GO:0016875 ligase activity, forming carbon-oxygen bonds 24/3692 41/18639 0.585365853658537 2.95520968210766 5.43835636132507e-08 3.81212540952916e-06 GO:0016874 ligase activity 63/3692 167/18639 0.377245508982036 1.90451761698704 5.62347692399488e-08 3.81212540952916e-06 GO:0016651 oxidoreductase activity, acting on NAD(P)H 39/3692 88/18639 0.443181818181818 2.23739596670935 1.49015067133673e-07 9.59657032340855e-06 GO:0003743 translation initiation factor activity 25/3692 51/18639 0.490196078431373 2.47474667006564 2.67308419990351e-06 0.000163949164260749 GO:0016853 isomerase activity 59/3692 180/18639 0.327777777777778 1.65478060671723 2.6045169925025e-05 0.00152482631197419 GO:0015631 tubulin binding 109/3692 385/18639 0.283116883116883 1.42931083001506 3.21361601690428e-05 0.0017996249694664 GO:0015399 primary active transmembrane transporter activity 55/3692 166/18639 0.331325301204819 1.67269021916485 3.43297253434629e-05 0.00184236192676584 GO:0008135 translation factor activity, RNA binding 32/3692 83/18639 0.385542168674699 1.9464031641191 6.01180222153364e-05 0.00309728050453413 GO:0015036 disulfide oxidoreductase activity 19/3692 40/18639 0.475 2.39802952329361 7.28176301237834e-05 0.00360727336920896 GO:0180051 translation factor activity 32/3692 84/18639 0.380952380952381 1.92323169787959 7.88413051673346e-05 0.00376102226131582 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 11/3692 18/18639 0.611111111111111 3.08518418201517 0.00014402444860153 0.00662512463567039 GO:0016859 cis-trans isomerase activity 19/3692 42/18639 0.452380952380952 2.28383764123201 0.000164721338616735 0.00731589945304671 GO:0005525 GTP binding 103/3692 378/18639 0.272486772486772 1.37564489501109 0.000256187153777301 0.0109989684688388 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 22/3692 54/18639 0.407407407407407 2.05678945467678 0.000332184809961679 0.0138017430719562 GO:0016835 carbon-oxygen lyase activity 29/3692 79/18639 0.367088607594937 1.85324067089979 0.000350674216990461 0.0141146372338661 GO:0061650 ubiquitin-like protein conjugating enzyme activity 18/3692 41/18639 0.439024390243902 2.21640726158074 0.000384445618264536 0.015005028979537 GO:0098632 cell-cell adhesion mediator activity 22/3692 55/18639 0.4 2.01939328277356 0.000451073859108442 0.0161526794732295 GO:0032977 membrane insertase activity 10/3692 17/18639 0.588235294117647 2.96969600407877 0.000451472407636848 0.0161526794732295 GO:0070402 NADPH binding 10/3692 17/18639 0.588235294117647 2.96969600407877 0.000451472407636848 0.0161526794732295 GO:0051117 ATPase binding 30/3692 84/18639 0.357142857142857 1.80302971676211 0.000481469210109194 0.0167603335843417 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 11/3692 20/18639 0.55 2.77666576381365 0.000512487962039389 0.0173706446080719 GO:0004300 enoyl-CoA hydratase activity 8/3692 12/18639 0.666666666666667 3.36565547128927 0.000539966596380984 0.0178327429779156 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 17/3692 39/18639 0.435897435897436 2.20062088507376 0.000614056198166088 0.019772609580948 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 16/3692 36/18639 0.444444444444444 2.24377031419285 0.000680704212259931 0.0203894657067626 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 16/3692 36/18639 0.444444444444444 2.24377031419285 0.000680704212259931 0.0203894657067626 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 16/3692 36/18639 0.444444444444444 2.24377031419285 0.000680704212259931 0.0203894657067626 GO:0045504 dynein heavy chain binding 9/3692 15/18639 0.6 3.02908992416035 0.000724732119496874 0.0207434437758217 GO:0055105 ubiquitin-protein transferase inhibitor activity 9/3692 15/18639 0.6 3.02908992416035 0.000724732119496874 0.0207434437758217 GO:0047429 nucleoside triphosphate diphosphatase activity 7/3692 10/18639 0.7 3.53393824485374 0.000809849300062315 0.0224268265642316 GO:0070064 proline-rich region binding 10/3692 18/18639 0.555555555555556 2.80471289274106 0.000835782356430993 0.0224268265642316 GO:0070628 proteasome binding 10/3692 18/18639 0.555555555555556 2.80471289274106 0.000835782356430993 0.0224268265642316 GO:0019001 guanyl nucleotide binding 105/3692 400/18639 0.2625 1.32522684182015 0.000945762493515851 0.0243628418329683 GO:0032561 guanyl ribonucleotide binding 105/3692 400/18639 0.2625 1.32522684182015 0.000945762493515851 0.0243628418329683 GO:0015035 protein-disulfide reductase activity 15/3692 34/18639 0.441176470588235 2.22727200305908 0.00109320466790362 0.0276087767109777 GO:0008017 microtubule binding 76/3692 276/18639 0.27536231884058 1.39016204248905 0.00112023915227842 0.0277474620795116 GO:0140318 protein transporter activity 17/3692 41/18639 0.414634146341463 2.09327352482626 0.00121841136375225 0.0296096950285452 GO:0016866 intramolecular transferase activity 13/3692 28/18639 0.464285714285714 2.34393863179074 0.00131122287082227 0.0312750936596127 GO:0043023 ribosomal large subunit binding 9/3692 16/18639 0.5625 2.83977180390033 0.00136589573471287 0.031986794660185 GO:0034062 5'-3' RNA polymerase activity 11/3692 22/18639 0.5 2.52424160346696 0.00145363193775853 0.0328469813304033 GO:0097747 RNA polymerase activity 11/3692 22/18639 0.5 2.52424160346696 0.00145363193775853 0.0328469813304033 GO:0031625 ubiquitin protein ligase binding 81/3692 302/18639 0.268211920529801 1.35406337669419 0.00179121770960698 0.039618831665692 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 7/3692 11/18639 0.636363636363636 3.21267113168522 0.0018455977484018 0.039618831665692 GO:0070990 snRNP binding 7/3692 11/18639 0.636363636363636 3.21267113168522 0.0018455977484018 0.039618831665692 GO:0055106 ubiquitin-protein transferase regulator activity 15/3692 36/18639 0.416666666666667 2.1035346695558 0.00219864351864116 0.0460830224523131 GO:0019888 protein phosphatase regulator activity 34/3692 107/18639 0.317757009345794 1.60419092556778 0.00222890258527947 0.0460830224523131 GO:0016836 hydro-lyase activity 22/3692 61/18639 0.360655737704918 1.82076443528764 0.00225406088081966 0.0460830224523131 GO:0048306 calcium-dependent protein binding 27/3692 80/18639 0.3375 1.7038630823402 0.00234723662682312 0.046693448438618 GO:0003924 GTPase activity 87/3692 331/18639 0.262839879154079 1.3269427160219 0.00235642402834641 0.046693448438618 GO:0051020 GTPase binding 83/3692 315/18639 0.263492063492063 1.33023525770005 0.00271457636287432 0.0529753690209413 GO:0019205 nucleobase-containing compound kinase activity 17/3692 44/18639 0.386363636363636 1.95055032995174 0.00301693742162292 0.057997244761945 GO:0051082 unfolded protein binding 37/3692 121/18639 0.305785123966942 1.54375106327731 0.00309410925890642 0.0580646459508268 GO:0008320 protein transmembrane transporter activity 12/3692 27/18639 0.444444444444444 2.24377031419285 0.00315568727993624 0.0580646459508268 GO:0015252 proton channel activity 12/3692 27/18639 0.444444444444444 2.24377031419285 0.00315568727993624 0.0580646459508268 GO:0044389 ubiquitin-like protein ligase binding 84/3692 322/18639 0.260869565217391 1.31699561920015 0.00345274384481011 0.0622504497006313 GO:0048027 mRNA 5'-UTR binding 11/3692 24/18639 0.458333333333333 2.31388813651138 0.00347983880314088 0.0622504497006313 GO:1990381 ubiquitin-specific protease binding 9/3692 18/18639 0.5 2.52424160346696 0.00395346159891579 0.0663412730933195 GO:0004129 cytochrome-c oxidase activity 8/3692 15/18639 0.533333333333333 2.69252437703142 0.00396605436970932 0.0663412730933195 GO:0008252 nucleotidase activity 8/3692 15/18639 0.533333333333333 2.69252437703142 0.00396605436970932 0.0663412730933195 GO:0031386 protein tag activity 8/3692 15/18639 0.533333333333333 2.69252437703142 0.00396605436970932 0.0663412730933195 GO:0141047 molecular tag activity 8/3692 15/18639 0.533333333333333 2.69252437703142 0.00396605436970932 0.0663412730933195 GO:0019003 GDP binding 25/3692 75/18639 0.333333333333333 1.68282773564464 0.00402351477141537 0.066439577251064 GO:0000175 3'-5'-RNA exonuclease activity 14/3692 35/18639 0.4 2.01939328277356 0.00476534214187912 0.0761590037283534 GO:0061631 ubiquitin conjugating enzyme activity 14/3692 35/18639 0.4 2.01939328277356 0.00476534214187912 0.0761590037283534 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 38/3692 128/18639 0.296875 1.4987684520585 0.00478950256366197 0.0761590037283534 GO:0098631 cell adhesion mediator activity 25/3692 76/18639 0.328947368421053 1.66068526543879 0.00488844517680389 0.0767843583868709 GO:0043130 ubiquitin binding 31/3692 100/18639 0.31 1.56502979414951 0.00512760289867282 0.0795705124516938 GO:0160215 deacylase activity 22/3692 65/18639 0.338461538461538 1.70871739311609 0.00548480832674246 0.0836447749962901 GO:0030515 snoRNA binding 13/3692 32/18639 0.40625 2.0509463028169 0.0055200356169912 0.0836447749962901 GO:0019208 phosphatase regulator activity 35/3692 117/18639 0.299145299145299 1.51023001916826 0.00578568581782337 0.0859080963605545 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 47/3692 167/18639 0.281437125748503 1.42083060314906 0.00580279843429212 0.0859080963605545 GO:0001094 TFIID-class transcription factor complex binding 6/3692 10/18639 0.6 3.02908992416035 0.00604450959417961 0.0859982858466361 GO:0016868 intramolecular phosphotransferase activity 6/3692 10/18639 0.6 3.02908992416035 0.00604450959417961 0.0859982858466361 GO:0050815 phosphoserine residue binding 6/3692 10/18639 0.6 3.02908992416035 0.00604450959417961 0.0859982858466361 GO:0008200 ion channel inhibitor activity 16/3692 43/18639 0.372093023255814 1.87850537932425 0.00607596584786016 0.0859982858466361 GO:0005484 SNAP receptor activity 14/3692 36/18639 0.388888888888889 1.96329902491874 0.00639869581121239 0.0895817413569735 GO:0016675 oxidoreductase activity, acting on a heme group of donors 8/3692 16/18639 0.5 2.52424160346696 0.00656621300470577 0.090516585754292 GO:0008253 5'-nucleotidase activity 7/3692 13/18639 0.538461538461538 2.71841403450288 0.00660602411560826 0.090516585754292 GO:0004532 RNA exonuclease activity 15/3692 40/18639 0.375 1.89318120260022 0.00716650466237131 0.0971627158435183 GO:0097602 cullin family protein binding 11/3692 26/18639 0.423076923076923 2.13589674139512 0.00730059616127034 0.0979496651637104 GO:0016248 channel inhibitor activity 16/3692 44/18639 0.363636363636364 1.8358120752487 0.00782398209142433 0.103065401372442 GO:0000287 magnesium ion binding 61/3692 230/18639 0.265217391304348 1.33894554618682 0.00787147482916786 0.103065401372442 GO:0008168 methyltransferase activity 55/3692 204/18639 0.269607843137255 1.3611106685361 0.00792195243468303 0.103065401372442 GO:0016829 lyase activity 54/3692 200/18639 0.27 1.36309046587216 0.00819416735089015 0.105540875479465 GO:0008171 O-methyltransferase activity 10/3692 23/18639 0.434782608695652 2.19499269866692 0.00830123328254373 0.105861271959568 GO:0019213 deacetylase activity 14/3692 37/18639 0.378378378378378 1.91023688911013 0.00844979305483779 0.106699347594422 GO:0032182 ubiquitin-like protein binding 35/3692 120/18639 0.291666666666667 1.47247426868906 0.00885770815612588 0.110764350534856 GO:0005200 structural constituent of cytoskeleton 33/3692 112/18639 0.294642857142857 1.48749951632874 0.00920851945097618 0.113287450000832 GO:0031418 L-ascorbic acid binding 9/3692 20/18639 0.45 2.27181744312026 0.00932334604044117 0.113287450000832 GO:0043024 ribosomal small subunit binding 9/3692 20/18639 0.45 2.27181744312026 0.00932334604044117 0.113287450000832 GO:0141110 transporter inhibitor activity 16/3692 45/18639 0.355555555555556 1.79501625135428 0.00995184514482254 0.11979417333207 GO:0004364 glutathione transferase activity 11/3692 27/18639 0.407407407407407 2.05678945467678 0.0101502210171875 0.121050783982755 GO:0004550 nucleoside diphosphate kinase activity 8/3692 17/18639 0.470588235294118 2.37575680326302 0.0102742939176234 0.121406335466963 GO:0016860 intramolecular oxidoreductase activity 18/3692 53/18639 0.339622641509434 1.71457920235491 0.0109499508041849 0.125228787784736 GO:0140296 general transcription initiation factor binding 18/3692 53/18639 0.339622641509434 1.71457920235491 0.0109499508041849 0.125228787784736 GO:0044548 S100 protein binding 7/3692 14/18639 0.5 2.52424160346696 0.0109746990616205 0.125228787784736 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 14/3692 38/18639 0.368421052631579 1.85996749729144 0.010986687127077 0.125228787784736 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 20/3692 61/18639 0.327868852459016 1.65524039571604 0.0115459382381466 0.13044884605906 GO:0031492 nucleosomal DNA binding 15/3692 42/18639 0.357142857142857 1.80302971676211 0.0118324981690074 0.131381531393807 GO:0048487 beta-tubulin binding 15/3692 42/18639 0.357142857142857 1.80302971676211 0.0118324981690074 0.131381531393807 GO:0003925 G protein activity 18/3692 54/18639 0.333333333333333 1.68282773564464 0.0134513586507708 0.147915938514936 GO:0008408 3'-5' exonuclease activity 19/3692 58/18639 0.327586206896552 1.65381346434042 0.0137452893639694 0.147915938514936 GO:0016209 antioxidant activity 26/3692 86/18639 0.302325581395349 1.52628562070095 0.0137661424240407 0.147915938514936 GO:0051537 2 iron, 2 sulfur cluster binding 11/3692 28/18639 0.392857142857143 1.98333268843832 0.0137809880603978 0.147915938514936 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 14/3692 39/18639 0.358974358974359 1.81227602300192 0.014080298586936 0.149879541983252 GO:0016741 transferase activity, transferring one-carbon groups 56/3692 215/18639 0.26046511627907 1.31495376552697 0.0151949665109758 0.16041899070604 GO:0022884 macromolecule transmembrane transporter activity 12/3692 32/18639 0.375 1.89318120260022 0.0154438004008664 0.161636009222171 GO:0043495 protein-membrane adaptor activity 16/3692 47/18639 0.340425531914894 1.71863258108388 0.0155612307015134 0.161636009222171 GO:0072341 modified amino acid binding 27/3692 91/18639 0.296703296703297 1.49790161084852 0.0157648507740089 0.162441022375388 GO:0017025 TBP-class protein binding 10/3692 25/18639 0.4 2.01939328277356 0.0161653548531497 0.165245849609974 GO:0001786 phosphatidylserine binding 19/3692 59/18639 0.322033898305085 1.62578272765668 0.0165993404699101 0.168346067127907 GO:0008173 RNA methyltransferase activity 21/3692 67/18639 0.313432835820896 1.58236040814346 0.0167474965862741 0.168521684399383 GO:0000774 adenyl-nucleotide exchange factor activity 7/3692 15/18639 0.466666666666667 2.35595882990249 0.0171072631670428 0.170807402784117 GO:0003779 actin binding 106/3692 443/18639 0.239277652370203 1.20798920978554 0.0176796176079567 0.175164211377294 GO:0051087 protein-folding chaperone binding 37/3692 134/18639 0.276119402985075 1.39398416907877 0.0178828513573977 0.17582528662846 GO:0016423 tRNA (guanine) methyltransferase activity 6/3692 12/18639 0.5 2.52424160346696 0.018492926256995 0.180446128931891 GO:0003712 transcription coregulator activity 117/3692 495/18639 0.236363636363636 1.19327784891165 0.0190007970563869 0.184007718861852 GO:0051540 metal cluster binding 23/3692 77/18639 0.298701298701299 1.50798849038286 0.022684928200233 0.218046175536568 GO:0060590 ATPase regulator activity 16/3692 49/18639 0.326530612244898 1.64848431246822 0.0233455655362508 0.222733988227341 GO:0004864 protein phosphatase inhibitor activity 17/3692 53/18639 0.320754716981132 1.61932480222408 0.0236006082835439 0.223511643155916 GO:0003714 transcription corepressor activity 52/3692 204/18639 0.254901960784314 1.28686826843413 0.0276615168564576 0.260058640227134 GO:0009982 pseudouridine synthase activity 6/3692 13/18639 0.461538461538462 2.33006917243104 0.0286816995210408 0.262000205553904 GO:0019104 DNA N-glycosylase activity 6/3692 13/18639 0.461538461538462 2.33006917243104 0.0286816995210408 0.262000205553904 GO:0019855 calcium channel inhibitor activity 6/3692 13/18639 0.461538461538462 2.33006917243104 0.0286816995210408 0.262000205553904 GO:0031994 insulin-like growth factor I binding 6/3692 13/18639 0.461538461538462 2.33006917243104 0.0286816995210408 0.262000205553904 GO:0016408 C-acyltransferase activity 8/3692 20/18639 0.4 2.01939328277356 0.0303985336351819 0.272322126768656 GO:0061608 nuclear import signal receptor activity 8/3692 20/18639 0.4 2.01939328277356 0.0303985336351819 0.272322126768656 GO:0005528 FK506 binding 5/3692 10/18639 0.5 2.52424160346696 0.0315031031743243 0.272322126768656 GO:0033204 ribonuclease P RNA binding 5/3692 10/18639 0.5 2.52424160346696 0.0315031031743243 0.272322126768656 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 5/3692 10/18639 0.5 2.52424160346696 0.0315031031743243 0.272322126768656 GO:0070739 protein-glutamic acid ligase activity 5/3692 10/18639 0.5 2.52424160346696 0.0315031031743243 0.272322126768656 GO:0070740 tubulin-glutamic acid ligase activity 5/3692 10/18639 0.5 2.52424160346696 0.0315031031743243 0.272322126768656 GO:0097177 mitochondrial ribosome binding 5/3692 10/18639 0.5 2.52424160346696 0.0315031031743243 0.272322126768656 GO:0140566 histone reader activity 12/3692 35/18639 0.342857142857143 1.73090852809163 0.0319587443404732 0.273253783979469 GO:0052689 carboxylic ester hydrolase activity 26/3692 92/18639 0.282608695652174 1.4267452541335 0.0320351874075309 0.273253783979469 GO:0031593 polyubiquitin modification-dependent protein binding 18/3692 59/18639 0.305084745762712 1.54021521567475 0.0332634073494933 0.281863609645706 GO:0001091 RNA polymerase II general transcription initiation factor binding 9/3692 24/18639 0.375 1.89318120260022 0.0340864646322038 0.285544094468224 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 57/3692 229/18639 0.248908296943231 1.25660935718442 0.0341411417298964 0.285544094468224 GO:0051536 iron-sulfur cluster binding 22/3692 76/18639 0.289473684210526 1.46140303358613 0.0357729287283489 0.293926131888196 GO:0004549 tRNA-specific ribonuclease activity 7/3692 17/18639 0.411764705882353 2.07878720285514 0.0358279524118376 0.293926131888196 GO:0016018 cyclosporin A binding 7/3692 17/18639 0.411764705882353 2.07878720285514 0.0358279524118376 0.293926131888196 GO:0019787 ubiquitin-like protein transferase activity 111/3692 479/18639 0.231732776617954 1.16989903125191 0.0366520071789296 0.29878345092697 GO:0140142 nucleocytoplasmic carrier activity 11/3692 32/18639 0.34375 1.73541610238353 0.0384394206793473 0.31138348323899 GO:0019212 phosphatase inhibitor activity 17/3692 56/18639 0.303571428571429 1.53257525924779 0.0395947362706735 0.317429100873815 GO:0008170 N-methyltransferase activity 27/3692 98/18639 0.275510204081633 1.39090863864506 0.0396938054987507 0.317429100873815 GO:0061791 GTPase motor activity 13/3692 40/18639 0.325 1.64075704225352 0.0401715399397763 0.317429100873815 GO:1990606 membrane scission GTPase motor activity 13/3692 40/18639 0.325 1.64075704225352 0.0401715399397763 0.317429100873815 GO:0072542 protein phosphatase activator activity 8/3692 21/18639 0.380952380952381 1.92323169787959 0.0408017338971956 0.318500807633866 GO:1904047 S-adenosyl-L-methionine binding 8/3692 21/18639 0.380952380952381 1.92323169787959 0.0408017338971956 0.318500807633866 GO:0019211 phosphatase activator activity 9/3692 25/18639 0.36 1.81745395449621 0.0441670888829217 0.342694039043393 GO:0003684 damaged DNA binding 21/3692 74/18639 0.283783783783784 1.4326776668326 0.0482443336494647 0.369783168878836 GO:0019206 nucleoside kinase activity 5/3692 11/18639 0.454545454545455 2.29476509406087 0.0485196859786671 0.369783168878836 GO:1990948 ubiquitin ligase inhibitor activity 5/3692 11/18639 0.454545454545455 2.29476509406087 0.0485196859786671 0.369783168878836 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 8/3692 22/18639 0.363636363636364 1.8358120752487 0.0533187652147039 0.400802724682536 GO:0140035 ubiquitin-like protein reader activity 8/3692 22/18639 0.363636363636364 1.8358120752487 0.0533187652147039 0.400802724682536 GO:0004857 enzyme inhibitor activity 96/3692 416/18639 0.230769230769231 1.16503458621552 0.0535233452215809 0.400802724682536 GO:0050661 NADP binding 16/3692 54/18639 0.296296296296296 1.49584687612857 0.0551415595743307 0.407927385287773 GO:0051287 NAD binding 16/3692 54/18639 0.296296296296296 1.49584687612857 0.0551415595743307 0.407927385287773 GO:0008157 protein phosphatase 1 binding 9/3692 26/18639 0.346153846153846 1.74755187932328 0.0560583440962234 0.407927385287773 GO:0008198 ferrous iron binding 9/3692 26/18639 0.346153846153846 1.74755187932328 0.0560583440962234 0.407927385287773 GO:0120014 phospholipid transfer activity 9/3692 26/18639 0.346153846153846 1.74755187932328 0.0560583440962234 0.407927385287773 GO:0004860 protein kinase inhibitor activity 23/3692 84/18639 0.273809523809524 1.38232278285095 0.0579122849592443 0.419050691165767 GO:0008175 tRNA methyltransferase activity 11/3692 34/18639 0.323529411764706 1.63333280224332 0.0582778687848648 0.419340195502267 GO:0005520 insulin-like growth factor binding 7/3692 19/18639 0.368421052631579 1.85996749729144 0.0645649300235079 0.456921043243287 GO:0097001 ceramide binding 7/3692 19/18639 0.368421052631579 1.85996749729144 0.0645649300235079 0.456921043243287 GO:0120227 acyl-CoA binding 7/3692 19/18639 0.368421052631579 1.85996749729144 0.0645649300235079 0.456921043243287 GO:0016755 aminoacyltransferase activity 112/3692 496/18639 0.225806451612903 1.13998007898508 0.0667559021114367 0.462241367059939 GO:0004842 ubiquitin-protein transferase activity 102/3692 449/18639 0.2271714922049 1.14687146349055 0.0677947458097903 0.462241367059939 GO:0004602 glutathione peroxidase activity 8/3692 23/18639 0.347826086956522 1.75599415893353 0.0680442678220545 0.462241367059939 GO:0140102 catalytic activity, acting on a rRNA 8/3692 23/18639 0.347826086956522 1.75599415893353 0.0680442678220545 0.462241367059939 GO:0016776 phosphotransferase activity, phosphate group as acceptor 12/3692 39/18639 0.307692307692308 1.55337944828736 0.0696455924894728 0.462241367059939 GO:0001671 ATPase activator activity 9/3692 27/18639 0.333333333333333 1.68282773564464 0.069835893385846 0.462241367059939 GO:0019210 kinase inhibitor activity 24/3692 90/18639 0.266666666666667 1.34626218851571 0.0699215868124039 0.462241367059939 GO:0004526 ribonuclease P activity 5/3692 12/18639 0.416666666666667 2.1035346695558 0.0699673714941472 0.462241367059939 GO:0005095 GTPase inhibitor activity 5/3692 12/18639 0.416666666666667 2.1035346695558 0.0699673714941472 0.462241367059939 GO:0005527 macrolide binding 5/3692 12/18639 0.416666666666667 2.1035346695558 0.0699673714941472 0.462241367059939 GO:0031543 peptidyl-proline dioxygenase activity 5/3692 12/18639 0.416666666666667 2.1035346695558 0.0699673714941472 0.462241367059939 GO:0097371 MDM2/MDM4 family protein binding 5/3692 12/18639 0.416666666666667 2.1035346695558 0.0699673714941472 0.462241367059939 GO:0070273 phosphatidylinositol-4-phosphate binding 10/3692 31/18639 0.32258064516129 1.62854296997868 0.0704834771622598 0.462241367059939 GO:0004540 RNA nuclease activity 31/3692 121/18639 0.256198347107438 1.29341305301613 0.0706375793608692 0.462241367059939 GO:0140767 enzyme-substrate adaptor activity 35/3692 139/18639 0.251798561151079 1.27120080750134 0.0713000854404164 0.462241367059939 GO:0001098 basal transcription machinery binding 17/3692 60/18639 0.283333333333333 1.43040357529794 0.0714177267429564 0.462241367059939 GO:0001099 basal RNA polymerase II transcription machinery binding 17/3692 60/18639 0.283333333333333 1.43040357529794 0.0714177267429564 0.462241367059939 GO:0019903 protein phosphatase binding 36/3692 144/18639 0.25 1.26212080173348 0.0743795604751835 0.479004369460182 GO:0016879 ligase activity, forming carbon-nitrogen bonds 14/3692 48/18639 0.291666666666667 1.47247426868906 0.0782648429321686 0.497861305364074 GO:0000062 fatty-acyl-CoA binding 6/3692 16/18639 0.375 1.89318120260022 0.0784672709541204 0.497861305364074 GO:0004708 MAP kinase kinase activity 6/3692 16/18639 0.375 1.89318120260022 0.0784672709541204 0.497861305364074 GO:0019905 syntaxin binding 17/3692 61/18639 0.278688524590164 1.40695433635863 0.0814674431294887 0.514363072307752 GO:0044390 ubiquitin-like protein conjugating enzyme binding 11/3692 36/18639 0.305555555555556 1.54259209100758 0.0838874138461561 0.527058483091947 GO:0004601 peroxidase activity 16/3692 57/18639 0.280701754385965 1.41711809317443 0.0844347980040133 0.52792242635519 GO:0097110 scaffold protein binding 19/3692 70/18639 0.271428571428571 1.3703025847392 0.0853795225313911 0.529691472422562 GO:0097718 disordered domain specific binding 9/3692 28/18639 0.321428571428571 1.6227267450859 0.0855402377825255 0.529691472422562 GO:0033218 amide binding 58/3692 247/18639 0.234817813765182 1.18547378948246 0.0860523787646186 0.530313224157075 GO:0004527 exonuclease activity 22/3692 84/18639 0.261904761904762 1.32222179229222 0.0940058935750594 0.576415609452393 GO:0002161 aminoacyl-tRNA editing activity 5/3692 13/18639 0.384615384615385 1.9417243103592 0.0957709164773387 0.576415609452393 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 5/3692 13/18639 0.384615384615385 1.9417243103592 0.0957709164773387 0.576415609452393 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 5/3692 13/18639 0.384615384615385 1.9417243103592 0.0957709164773387 0.576415609452393 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 5/3692 13/18639 0.384615384615385 1.9417243103592 0.0957709164773387 0.576415609452393 GO:0140463 chromatin-protein adaptor activity 15/3692 54/18639 0.277777777777778 1.40235644637053 0.0998514593558091 0.595272302340052 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 10/3692 33/18639 0.303030303030303 1.52984339604058 0.101303880967877 0.595272302340052 GO:0005092 GDP-dissociation inhibitor activity 6/3692 17/18639 0.352941176470588 1.78181760244726 0.101725081068093 0.595272302340052 GO:0031489 myosin V binding 6/3692 17/18639 0.352941176470588 1.78181760244726 0.101725081068093 0.595272302340052 GO:0048038 quinone binding 6/3692 17/18639 0.352941176470588 1.78181760244726 0.101725081068093 0.595272302340052 GO:1901567 fatty acid derivative binding 6/3692 17/18639 0.352941176470588 1.78181760244726 0.101725081068093 0.595272302340052 GO:0016417 S-acyltransferase activity 9/3692 29/18639 0.310344827586207 1.56677065042777 0.103175412379005 0.595272302340052 GO:0043236 laminin binding 9/3692 29/18639 0.310344827586207 1.56677065042777 0.103175412379005 0.595272302340052 GO:0010314 phosphatidylinositol-5-phosphate binding 7/3692 21/18639 0.333333333333333 1.68282773564464 0.104042463631081 0.595272302340052 GO:0000030 mannosyltransferase activity 8/3692 25/18639 0.32 1.61551462621885 0.104249560256537 0.595272302340052 GO:0003774 cytoskeletal motor activity 37/3692 153/18639 0.241830065359477 1.22087502389905 0.105385136382981 0.595272302340052 GO:0019902 phosphatase binding 45/3692 190/18639 0.236842105263158 1.19569339111593 0.106194434673391 0.595272302340052 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 16/3692 59/18639 0.271186440677966 1.36908019171089 0.108665649996479 0.595272302340052 GO:0033192 calmodulin-dependent protein phosphatase activity 21/3692 81/18639 0.259259259259259 1.3088660166125 0.108850939128915 0.595272302340052 GO:0140791 histone H2AXS140 phosphatase activity 21/3692 81/18639 0.259259259259259 1.3088660166125 0.108850939128915 0.595272302340052 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 21/3692 81/18639 0.259259259259259 1.3088660166125 0.108850939128915 0.595272302340052 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 21/3692 81/18639 0.259259259259259 1.3088660166125 0.108850939128915 0.595272302340052 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 21/3692 81/18639 0.259259259259259 1.3088660166125 0.108850939128915 0.595272302340052 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 21/3692 81/18639 0.259259259259259 1.3088660166125 0.108850939128915 0.595272302340052 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 21/3692 81/18639 0.259259259259259 1.3088660166125 0.108850939128915 0.595272302340052 GO:1990439 MAP kinase serine/threonine phosphatase activity 21/3692 81/18639 0.259259259259259 1.3088660166125 0.108850939128915 0.595272302340052 GO:0051015 actin filament binding 49/3692 209/18639 0.23444976076555 1.18361568009455 0.109071633037463 0.595272302340052 GO:0003713 transcription coactivator activity 59/3692 256/18639 0.23046875 1.16351761409805 0.110593088343712 0.601029104585239 GO:0000182 rDNA binding 4/3692 10/18639 0.4 2.01939328277356 0.117458070924352 0.612493908301885 GO:0004090 carbonyl reductase (NADPH) activity 4/3692 10/18639 0.4 2.01939328277356 0.117458070924352 0.612493908301885 GO:0016427 tRNA (cytidine) methyltransferase activity 4/3692 10/18639 0.4 2.01939328277356 0.117458070924352 0.612493908301885 GO:0016783 sulfurtransferase activity 4/3692 10/18639 0.4 2.01939328277356 0.117458070924352 0.612493908301885 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 4/3692 10/18639 0.4 2.01939328277356 0.117458070924352 0.612493908301885 GO:0019911 structural constituent of myelin sheath 4/3692 10/18639 0.4 2.01939328277356 0.117458070924352 0.612493908301885 GO:0031419 cobalamin binding 4/3692 10/18639 0.4 2.01939328277356 0.117458070924352 0.612493908301885 GO:0043295 glutathione binding 4/3692 10/18639 0.4 2.01939328277356 0.117458070924352 0.612493908301885 GO:0043422 protein kinase B binding 4/3692 10/18639 0.4 2.01939328277356 0.117458070924352 0.612493908301885 GO:0070513 death domain binding 4/3692 10/18639 0.4 2.01939328277356 0.117458070924352 0.612493908301885 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 21/3692 82/18639 0.25609756097561 1.2929042359221 0.120246152756802 0.621996163657675 GO:0033549 MAP kinase phosphatase activity 21/3692 82/18639 0.25609756097561 1.2929042359221 0.120246152756802 0.621996163657675 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 16/3692 60/18639 0.266666666666667 1.34626218851571 0.122210349361396 0.629627719909913 GO:0031624 ubiquitin conjugating enzyme binding 9/3692 30/18639 0.3 1.51454496208017 0.122709117465487 0.629678658547996 GO:0005347 ATP transmembrane transporter activity 5/3692 14/18639 0.357142857142857 1.80302971676211 0.12566478681719 0.632266513954733 GO:0016530 metallochaperone activity 5/3692 14/18639 0.357142857142857 1.80302971676211 0.12566478681719 0.632266513954733 GO:0098847 sequence-specific single stranded DNA binding 5/3692 14/18639 0.357142857142857 1.80302971676211 0.12566478681719 0.632266513954733 GO:1901612 cardiolipin binding 5/3692 14/18639 0.357142857142857 1.80302971676211 0.12566478681719 0.632266513954733 GO:0050750 low-density lipoprotein particle receptor binding 8/3692 26/18639 0.307692307692308 1.55337944828736 0.125667878550009 0.632266513954733 GO:0008649 rRNA methyltransferase activity 7/3692 22/18639 0.318181818181818 1.60633556584261 0.127713522892057 0.637295810865541 GO:0016881 acid-amino acid ligase activity 7/3692 22/18639 0.318181818181818 1.60633556584261 0.127713522892057 0.637295810865541 GO:1901611 phosphatidylglycerol binding 6/3692 18/18639 0.333333333333333 1.68282773564464 0.128151875011006 0.637295810865541 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 21/3692 83/18639 0.253012048192771 1.27732707645316 0.13233583485686 0.655571366521674 GO:0005154 epidermal growth factor receptor binding 10/3692 35/18639 0.285714285714286 1.44242377340969 0.138787620133034 0.682284178363924 GO:0043015 gamma-tubulin binding 10/3692 35/18639 0.285714285714286 1.44242377340969 0.138787620133034 0.682284178363924 GO:0016504 peptidase activator activity 15/3692 57/18639 0.263157894736842 1.32854821235103 0.143249959443403 0.701543527616364 GO:0017018 myosin phosphatase activity 21/3692 84/18639 0.25 1.26212080173348 0.145112481950793 0.707767372160535 GO:0016790 thiolester hydrolase activity 12/3692 44/18639 0.272727272727273 1.37685905643652 0.146169348598371 0.707767372160535 GO:0043014 alpha-tubulin binding 12/3692 44/18639 0.272727272727273 1.37685905643652 0.146169348598371 0.707767372160535 GO:0005543 phospholipid binding 108/3692 497/18639 0.217303822937626 1.09705470090314 0.150936628119738 0.722147630028563 GO:0002162 dystroglycan binding 4/3692 11/18639 0.363636363636364 1.8358120752487 0.156851433750458 0.722147630028563 GO:0019107 myristoyltransferase activity 4/3692 11/18639 0.363636363636364 1.8358120752487 0.156851433750458 0.722147630028563 GO:0019215 intermediate filament binding 4/3692 11/18639 0.363636363636364 1.8358120752487 0.156851433750458 0.722147630028563 GO:0032794 GTPase activating protein binding 4/3692 11/18639 0.363636363636364 1.8358120752487 0.156851433750458 0.722147630028563 GO:0034511 U3 snoRNA binding 4/3692 11/18639 0.363636363636364 1.8358120752487 0.156851433750458 0.722147630028563 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 4/3692 11/18639 0.363636363636364 1.8358120752487 0.156851433750458 0.722147630028563 GO:0050786 RAGE receptor binding 4/3692 11/18639 0.363636363636364 1.8358120752487 0.156851433750458 0.722147630028563 GO:1900750 oligopeptide binding 4/3692 11/18639 0.363636363636364 1.8358120752487 0.156851433750458 0.722147630028563 GO:0005346 purine ribonucleotide transmembrane transporter activity 6/3692 19/18639 0.315789473684211 1.59425785482124 0.157499695774466 0.722147630028563 GO:0046624 sphingolipid transporter activity 6/3692 19/18639 0.315789473684211 1.59425785482124 0.157499695774466 0.722147630028563 GO:0070003 threonine-type peptidase activity 6/3692 19/18639 0.315789473684211 1.59425785482124 0.157499695774466 0.722147630028563 GO:0140036 ubiquitin-modified protein reader activity 6/3692 19/18639 0.315789473684211 1.59425785482124 0.157499695774466 0.722147630028563 GO:0140030 modification-dependent protein binding 40/3692 173/18639 0.23121387283237 1.16727935420437 0.157875245767265 0.722147630028563 GO:0004467 long-chain fatty acid-CoA ligase activity 5/3692 15/18639 0.333333333333333 1.68282773564464 0.159231309726795 0.722147630028563 GO:0016846 carbon-sulfur lyase activity 5/3692 15/18639 0.333333333333333 1.68282773564464 0.159231309726795 0.722147630028563 GO:0017081 chloride channel regulator activity 5/3692 15/18639 0.333333333333333 1.68282773564464 0.159231309726795 0.722147630028563 GO:0061578 K63-linked deubiquitinase activity 5/3692 15/18639 0.333333333333333 1.68282773564464 0.159231309726795 0.722147630028563 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 29/3692 122/18639 0.237704918032787 1.20004928689413 0.161307069646024 0.728994756856416 GO:0031267 small GTPase binding 63/3692 283/18639 0.222614840989399 1.12386728634925 0.166119297659535 0.745306874579381 GO:0031369 translation initiation factor binding 9/3692 32/18639 0.28125 1.41988590195016 0.167170967473207 0.745306874579381 GO:0051059 NF-kappaB binding 9/3692 32/18639 0.28125 1.41988590195016 0.167170967473207 0.745306874579381 GO:0015485 cholesterol binding 14/3692 54/18639 0.259259259259259 1.3088660166125 0.167809777661507 0.745306874579381 GO:0017069 snRNA binding 14/3692 54/18639 0.259259259259259 1.3088660166125 0.167809777661507 0.745306874579381 GO:0008276 protein methyltransferase activity 23/3692 95/18639 0.242105263157895 1.22226435536295 0.170136951015424 0.753046023738372 GO:0017080 sodium channel regulator activity 11/3692 41/18639 0.268292682926829 1.35447110429934 0.173660496865802 0.765047558002992 GO:0046625 sphingolipid binding 8/3692 28/18639 0.285714285714286 1.44242377340969 0.174630420848509 0.765047558002992 GO:0046875 ephrin receptor binding 8/3692 28/18639 0.285714285714286 1.44242377340969 0.174630420848509 0.765047558002992 GO:0042625 ATPase-coupled ion transmembrane transporter activity 7/3692 24/18639 0.291666666666667 1.47247426868906 0.182146443630914 0.786087780108486 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 7/3692 24/18639 0.291666666666667 1.47247426868906 0.182146443630914 0.786087780108486 GO:0046961 proton-transporting ATPase activity, rotational mechanism 7/3692 24/18639 0.291666666666667 1.47247426868906 0.182146443630914 0.786087780108486 GO:0070300 phosphatidic acid binding 7/3692 24/18639 0.291666666666667 1.47247426868906 0.182146443630914 0.786087780108486 GO:0030280 structural constituent of skin epidermis 10/3692 37/18639 0.27027027027027 1.36445492079295 0.18248466323947 0.786087780108486 GO:0016407 acetyltransferase activity 23/3692 96/18639 0.239583333333333 1.20953243499458 0.184005632677561 0.789997516295661 GO:0016505 peptidase activator activity involved in apoptotic process 6/3692 20/18639 0.3 1.51454496208017 0.189444328083614 0.810645496915932 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 15/3692 60/18639 0.25 1.26212080173348 0.19540648919835 0.816130185416441 GO:0008307 structural constituent of muscle 11/3692 42/18639 0.261904761904762 1.32222179229222 0.195691222717959 0.816130185416441 GO:0003688 DNA replication origin binding 5/3692 16/18639 0.3125 1.57765100216685 0.195942236441647 0.816130185416441 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 5/3692 16/18639 0.3125 1.57765100216685 0.195942236441647 0.816130185416441 GO:0005324 long-chain fatty acid transmembrane transporter activity 5/3692 16/18639 0.3125 1.57765100216685 0.195942236441647 0.816130185416441 GO:0008142 oxysterol binding 5/3692 16/18639 0.3125 1.57765100216685 0.195942236441647 0.816130185416441 GO:0034450 ubiquitin-ubiquitin ligase activity 5/3692 16/18639 0.3125 1.57765100216685 0.195942236441647 0.816130185416441 GO:0097027 ubiquitin-protein transferase activator activity 5/3692 16/18639 0.3125 1.57765100216685 0.195942236441647 0.816130185416441 GO:0005048 signal sequence binding 13/3692 51/18639 0.254901960784314 1.28686826843413 0.196428848974454 0.816130185416441 GO:0004859 phospholipase inhibitor activity 4/3692 12/18639 0.333333333333333 1.68282773564464 0.200293464878613 0.818977723059217 GO:0010853 cyclase activator activity 4/3692 12/18639 0.333333333333333 1.68282773564464 0.200293464878613 0.818977723059217 GO:0043047 single-stranded telomeric DNA binding 4/3692 12/18639 0.333333333333333 1.68282773564464 0.200293464878613 0.818977723059217 GO:0045295 gamma-catenin binding 4/3692 12/18639 0.333333333333333 1.68282773564464 0.200293464878613 0.818977723059217 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 4/3692 12/18639 0.333333333333333 1.68282773564464 0.200293464878613 0.818977723059217 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 8/3692 29/18639 0.275862068965517 1.39268502260246 0.201851376455939 0.820679267240582 GO:0016791 phosphatase activity 60/3692 273/18639 0.21978021978022 1.10955674877668 0.201983950089491 0.820679267240582 GO:0120013 lipid transfer activity 16/3692 65/18639 0.246153846153846 1.24270355862989 0.203558202200727 0.824474730926215 GO:0003697 single-stranded DNA binding 28/3692 121/18639 0.231404958677686 1.16824404788553 0.207137098945186 0.836340386963635 GO:0019706 protein-cysteine S-palmitoyltransferase activity 7/3692 25/18639 0.28 1.4135752979415 0.212439676054283 0.852405927594757 GO:0019707 protein-cysteine S-acyltransferase activity 7/3692 25/18639 0.28 1.4135752979415 0.212439676054283 0.852405927594757 GO:0019887 protein kinase regulator activity 56/3692 255/18639 0.219607843137255 1.10868650818941 0.213216358520994 0.852865434083977 GO:0035091 phosphatidylinositol binding 62/3692 284/18639 0.21830985915493 1.10213365785177 0.21400447739731 0.853367699342834 GO:0044183 protein folding chaperone 18/3692 75/18639 0.24 1.21163596966414 0.217804574569213 0.859998280052876 GO:0030332 cyclin binding 9/3692 34/18639 0.264705882352941 1.33636320183545 0.218021430905391 0.859998280052876 GO:0004722 protein serine/threonine phosphatase activity 24/3692 103/18639 0.233009708737864 1.17634560161567 0.218226569925483 0.859998280052876 GO:0016779 nucleotidyltransferase activity 31/3692 136/18639 0.227941176470588 1.15075720158052 0.218338072653176 0.859998280052876 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 6/3692 21/18639 0.285714285714286 1.44242377340969 0.223605073864628 0.87010071038562 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 6/3692 21/18639 0.285714285714286 1.44242377340969 0.223605073864628 0.87010071038562 GO:0051010 microtubule plus-end binding 6/3692 21/18639 0.285714285714286 1.44242377340969 0.223605073864628 0.87010071038562 GO:0140312 cargo adaptor activity 6/3692 21/18639 0.285714285714286 1.44242377340969 0.223605073864628 0.87010071038562 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 12/3692 48/18639 0.25 1.26212080173348 0.229703440837203 0.891138649994931 GO:0016769 transferase activity, transferring nitrogenous groups 8/3692 30/18639 0.266666666666667 1.34626218851571 0.230630379725195 0.892047835093245 GO:0004518 nuclease activity 46/3692 209/18639 0.220095693779904 1.11114941396632 0.23447304774597 0.898601191167105 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 5/3692 17/18639 0.294117647058824 1.48484800203939 0.235199384513961 0.898601191167105 GO:0051787 misfolded protein binding 5/3692 17/18639 0.294117647058824 1.48484800203939 0.235199384513961 0.898601191167105 GO:0070403 NAD+ binding 5/3692 17/18639 0.294117647058824 1.48484800203939 0.235199384513961 0.898601191167105 GO:0017022 myosin binding 18/3692 76/18639 0.236842105263158 1.19569339111593 0.235813045508138 0.898601191167105 GO:0001046 core promoter sequence-specific DNA binding 11/3692 44/18639 0.25 1.26212080173348 0.243121138004627 0.923716890117875 GO:0005112 Notch binding 7/3692 26/18639 0.269230769230769 1.35920701725144 0.244408233029543 0.925875894535443 GO:0004535 poly(A)-specific ribonuclease activity 4/3692 13/18639 0.307692307692308 1.55337944828736 0.246747930834735 0.929272909108591 GO:0005338 nucleotide-sugar transmembrane transporter activity 4/3692 13/18639 0.307692307692308 1.55337944828736 0.246747930834735 0.929272909108591 GO:0140104 molecular carrier activity 54/3692 249/18639 0.216867469879518 1.09485177981699 0.249059283805583 0.935243024902598 GO:0001222 transcription corepressor binding 12/3692 49/18639 0.244897959183673 1.23636323435116 0.253104439012452 0.947670108860575 GO:0005507 copper ion binding 15/3692 63/18639 0.238095238095238 1.20201981117474 0.25512712145311 0.952474586758277 GO:0004407 histone deacetylase activity 6/3692 22/18639 0.272727272727273 1.37685905643652 0.259564405479341 0.954059997291088 GO:0033558 protein lysine deacetylase activity 6/3692 22/18639 0.272727272727273 1.37685905643652 0.259564405479341 0.954059997291088 GO:0070034 telomerase RNA binding 6/3692 22/18639 0.272727272727273 1.37685905643652 0.259564405479341 0.954059997291088 GO:0140517 protein-RNA adaptor activity 6/3692 22/18639 0.272727272727273 1.37685905643652 0.259564405479341 0.954059997291088 GO:0016878 acid-thiol ligase activity 8/3692 31/18639 0.258064516129032 1.30283437598294 0.260736893669614 0.954059997291088 GO:0047499 calcium-independent phospholipase A2 activity 8/3692 31/18639 0.258064516129032 1.30283437598294 0.260736893669614 0.954059997291088 GO:0070325 lipoprotein particle receptor binding 8/3692 31/18639 0.258064516129032 1.30283437598294 0.260736893669614 0.954059997291088 GO:0005548 phospholipid transporter activity 16/3692 68/18639 0.235294117647059 1.18787840163151 0.261886084511287 0.955550359349964 GO:0051539 4 iron, 4 sulfur cluster binding 11/3692 45/18639 0.244444444444444 1.23407367280607 0.268278642171233 0.976109861911155 GO:0016409 palmitoyltransferase activity 9/3692 36/18639 0.25 1.26212080173348 0.273963664303051 0.993986477809378 GO:0016854 racemase and epimerase activity 5/3692 18/18639 0.277777777777778 1.40235644637053 0.276371503553559 0.997105032428528 GO:0035615 clathrin adaptor activity 5/3692 18/18639 0.277777777777778 1.40235644637053 0.276371503553559 0.997105032428528 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 10/3692 41/18639 0.24390243902439 1.23133736754486 0.28493899751719 1 GO:0016877 ligase activity, forming carbon-sulfur bonds 10/3692 41/18639 0.24390243902439 1.23133736754486 0.28493899751719 1 GO:0002020 protease binding 30/3692 136/18639 0.220588235294118 1.11363600152954 0.285103939003371 1 GO:0031491 nucleosome binding 17/3692 74/18639 0.22972972972973 1.15978668267401 0.288153551482015 1 GO:0019207 kinase regulator activity 61/3692 287/18639 0.212543554006969 1.07302256314623 0.289408639495041 1 GO:0047498 calcium-dependent phospholipase A2 activity 8/3692 32/18639 0.25 1.26212080173348 0.291925535735083 1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 14/3692 60/18639 0.233333333333333 1.17797941495125 0.292112716222456 1 GO:0030276 clathrin binding 11/3692 46/18639 0.239130434782609 1.20724598426681 0.294220687506361 1 GO:0030291 protein serine/threonine kinase inhibitor activity 11/3692 46/18639 0.239130434782609 1.20724598426681 0.294220687506361 1 GO:0008474 palmitoyl-(protein) hydrolase activity 4/3692 14/18639 0.285714285714286 1.44242377340969 0.295181188441752 1 GO:0008494 translation activator activity 4/3692 14/18639 0.285714285714286 1.44242377340969 0.295181188441752 1 GO:0098599 palmitoyl hydrolase activity 4/3692 14/18639 0.285714285714286 1.44242377340969 0.295181188441752 1 GO:0000295 adenine nucleotide transmembrane transporter activity 6/3692 23/18639 0.260869565217391 1.31699561920015 0.296886376124339 1 GO:0005158 insulin receptor binding 6/3692 23/18639 0.260869565217391 1.31699561920015 0.296886376124339 1 GO:0017134 fibroblast growth factor binding 6/3692 23/18639 0.260869565217391 1.31699561920015 0.296886376124339 1 GO:0042171 lysophosphatidic acid acyltransferase activity 6/3692 23/18639 0.260869565217391 1.31699561920015 0.296886376124339 1 GO:0071617 lysophospholipid acyltransferase activity 6/3692 23/18639 0.260869565217391 1.31699561920015 0.296886376124339 1 GO:0140103 catalytic activity, acting on a glycoprotein 6/3692 23/18639 0.260869565217391 1.31699561920015 0.296886376124339 1 GO:0016830 carbon-carbon lyase activity 12/3692 51/18639 0.235294117647059 1.18787840163151 0.302191404124197 1 GO:0016278 lysine N-methyltransferase activity 16/3692 70/18639 0.228571428571429 1.15393901872775 0.3037966458872 1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 7/3692 28/18639 0.25 1.26212080173348 0.312109173849833 1 GO:0003680 minor groove of adenine-thymine-rich DNA binding 3/3692 10/18639 0.3 1.51454496208017 0.31638974782528 1 GO:0005522 profilin binding 3/3692 10/18639 0.3 1.51454496208017 0.31638974782528 1 GO:0015643 toxic substance binding 3/3692 10/18639 0.3 1.51454496208017 0.31638974782528 1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 3/3692 10/18639 0.3 1.51454496208017 0.31638974782528 1 GO:0030957 Tat protein binding 3/3692 10/18639 0.3 1.51454496208017 0.31638974782528 1 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 3/3692 10/18639 0.3 1.51454496208017 0.31638974782528 1 GO:0031434 mitogen-activated protein kinase kinase binding 3/3692 10/18639 0.3 1.51454496208017 0.31638974782528 1 GO:0031957 very long-chain fatty acid-CoA ligase activity 3/3692 10/18639 0.3 1.51454496208017 0.31638974782528 1 GO:0031996 thioesterase binding 3/3692 10/18639 0.3 1.51454496208017 0.31638974782528 1 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 3/3692 10/18639 0.3 1.51454496208017 0.31638974782528 1 GO:0098505 G-rich strand telomeric DNA binding 3/3692 10/18639 0.3 1.51454496208017 0.31638974782528 1 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 3/3692 10/18639 0.3 1.51454496208017 0.31638974782528 1 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 3/3692 10/18639 0.3 1.51454496208017 0.31638974782528 1 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 3/3692 10/18639 0.3 1.51454496208017 0.31638974782528 1 GO:1990757 ubiquitin ligase activator activity 3/3692 10/18639 0.3 1.51454496208017 0.31638974782528 1 GO:0003756 protein disulfide isomerase activity 5/3692 19/18639 0.263157894736842 1.32854821235103 0.318825720617521 1 GO:0015245 fatty acid transmembrane transporter activity 5/3692 19/18639 0.263157894736842 1.32854821235103 0.318825720617521 1 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 5/3692 19/18639 0.263157894736842 1.32854821235103 0.318825720617521 1 GO:0042577 lipid phosphatase activity 5/3692 19/18639 0.263157894736842 1.32854821235103 0.318825720617521 1 GO:0046527 glucosyltransferase activity 5/3692 19/18639 0.263157894736842 1.32854821235103 0.318825720617521 1 GO:0050145 nucleoside monophosphate kinase activity 5/3692 19/18639 0.263157894736842 1.32854821235103 0.318825720617521 1 GO:0030296 protein tyrosine kinase activator activity 8/3692 33/18639 0.242424242424242 1.22387471683246 0.323942947198243 1 GO:0000146 microfilament motor activity 9/3692 38/18639 0.236842105263158 1.19569339111593 0.333455377534447 1 GO:0005109 frizzled binding 9/3692 38/18639 0.236842105263158 1.19569339111593 0.333455377534447 1 GO:0042162 telomeric DNA binding 9/3692 38/18639 0.236842105263158 1.19569339111593 0.333455377534447 1 GO:0043531 ADP binding 9/3692 38/18639 0.236842105263158 1.19569339111593 0.333455377534447 1 GO:0070840 dynein complex binding 6/3692 24/18639 0.25 1.26212080173348 0.335133020288813 1 GO:0004865 protein serine/threonine phosphatase inhibitor activity 4/3692 15/18639 0.266666666666667 1.34626218851571 0.344617507974464 1 GO:0005523 tropomyosin binding 4/3692 15/18639 0.266666666666667 1.34626218851571 0.344617507974464 1 GO:0015556 C4-dicarboxylate transmembrane transporter activity 4/3692 15/18639 0.266666666666667 1.34626218851571 0.344617507974464 1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 4/3692 15/18639 0.266666666666667 1.34626218851571 0.344617507974464 1 GO:0042809 nuclear vitamin D receptor binding 4/3692 15/18639 0.266666666666667 1.34626218851571 0.344617507974464 1 GO:0140776 protein-containing complex destabilizing activity 4/3692 15/18639 0.266666666666667 1.34626218851571 0.344617507974464 1 GO:0141050 histone H3K deacetylase activity 4/3692 15/18639 0.266666666666667 1.34626218851571 0.344617507974464 1 GO:0141051 histone H4K deacetylase activity 4/3692 15/18639 0.266666666666667 1.34626218851571 0.344617507974464 1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 7/3692 29/18639 0.241379310344828 1.21859939477715 0.347191200293345 1 GO:0051861 glycolipid binding 7/3692 29/18639 0.241379310344828 1.21859939477715 0.347191200293345 1 GO:0097472 cyclin-dependent protein kinase activity 7/3692 29/18639 0.241379310344828 1.21859939477715 0.347191200293345 1 GO:0032266 phosphatidylinositol-3-phosphate binding 11/3692 48/18639 0.229166666666667 1.15694406825569 0.347890878239012 1 GO:0019842 vitamin binding 32/3692 150/18639 0.213333333333333 1.07700975081257 0.350032111513413 1 GO:0061659 ubiquitin-like protein ligase activity 77/3692 372/18639 0.206989247311828 1.04498173906965 0.35170503607152 1 GO:0005544 calcium-dependent phospholipid binding 12/3692 53/18639 0.226415094339623 1.14305280156994 0.353523132531356 1 GO:0141108 transporter regulator activity 36/3692 170/18639 0.211764705882353 1.06909056146836 0.35581670802952 1 GO:0061630 ubiquitin protein ligase activity 73/3692 353/18639 0.206798866855524 1.04402060653308 0.359805779498922 1 GO:0044325 transmembrane transporter binding 29/3692 136/18639 0.213235294117647 1.07651480147855 0.360947412064616 1 GO:0140789 histone phosphatase activity 29/3692 136/18639 0.213235294117647 1.07651480147855 0.360947412064616 1 GO:0042288 MHC class I protein binding 5/3692 20/18639 0.25 1.26212080173348 0.361952851462157 1 GO:0032934 sterol binding 15/3692 68/18639 0.220588235294118 1.11363600152954 0.366424299489037 1 GO:0004521 RNA endonuclease activity 16/3692 73/18639 0.219178082191781 1.10651686727319 0.369773147027133 1 GO:0017056 structural constituent of nuclear pore 6/3692 25/18639 0.24 1.21163596966414 0.373878286889191 1 GO:0047617 fatty acyl-CoA hydrolase activity 6/3692 25/18639 0.24 1.21163596966414 0.373878286889191 1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0008526 phosphatidylinositol transfer activity 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0010854 adenylate cyclase regulator activity 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0015217 ADP transmembrane transporter activity 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0032050 clathrin heavy chain binding 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0045294 alpha-catenin binding 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0047676 arachidonate-CoA ligase activity 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0050998 nitric-oxide synthase binding 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0140031 phosphorylation-dependent protein binding 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 3/3692 11/18639 0.272727272727273 1.37685905643652 0.376216615603337 1 GO:0004197 cysteine-type endopeptidase activity 19/3692 88/18639 0.215909090909091 1.09001341967891 0.377925278226494 1 GO:0061134 peptidase regulator activity 47/3692 226/18639 0.207964601769911 1.0499057996721 0.379736039257751 1 GO:0001968 fibronectin binding 7/3692 30/18639 0.233333333333333 1.17797941495125 0.382666232640174 1 GO:0045309 protein phosphorylated amino acid binding 13/3692 59/18639 0.220338983050847 1.1123776557651 0.383506540832436 1 GO:0004623 phospholipase A2 activity 8/3692 35/18639 0.228571428571429 1.15393901872775 0.389448453715768 1 GO:0002039 p53 binding 15/3692 69/18639 0.217391304347826 1.09749634933346 0.389713181405863 1 GO:0016279 protein-lysine N-methyltransferase activity 15/3692 69/18639 0.217391304347826 1.09749634933346 0.389713181405863 1 GO:0031490 chromatin DNA binding 27/3692 128/18639 0.2109375 1.06491442646262 0.391462477460848 1 GO:0005149 interleukin-1 receptor binding 4/3692 16/18639 0.25 1.26212080173348 0.394175931818736 1 GO:0005159 insulin-like growth factor receptor binding 4/3692 16/18639 0.25 1.26212080173348 0.394175931818736 1 GO:0017070 U6 snRNA binding 4/3692 16/18639 0.25 1.26212080173348 0.394175931818736 1 GO:0055102 lipase inhibitor activity 4/3692 16/18639 0.25 1.26212080173348 0.394175931818736 1 GO:0070411 I-SMAD binding 4/3692 16/18639 0.25 1.26212080173348 0.394175931818736 1 GO:0140662 ATP-dependent protein folding chaperone 9/3692 40/18639 0.225 1.13590872156013 0.394859337888977 1 GO:0016247 channel regulator activity 35/3692 168/18639 0.208333333333333 1.0517673347779 0.399058573480149 1 GO:0005123 death receptor binding 5/3692 21/18639 0.238095238095238 1.20201981117474 0.405186531961384 1 GO:0070182 DNA polymerase binding 5/3692 21/18639 0.238095238095238 1.20201981117474 0.405186531961384 1 GO:0140313 molecular sequestering activity 12/3692 55/18639 0.218181818181818 1.10148724514922 0.406103331362763 1 GO:0005227 calcium-activated cation channel activity 6/3692 26/18639 0.230769230769231 1.16503458621552 0.412719303047085 1 GO:0015216 purine nucleotide transmembrane transporter activity 6/3692 26/18639 0.230769230769231 1.16503458621552 0.412719303047085 1 GO:0016289 acyl-CoA hydrolase activity 6/3692 26/18639 0.230769230769231 1.16503458621552 0.412719303047085 1 GO:0005310 dicarboxylic acid transmembrane transporter activity 7/3692 31/18639 0.225806451612903 1.13998007898508 0.418228956506587 1 GO:0008327 methyl-CpG binding 7/3692 31/18639 0.225806451612903 1.13998007898508 0.418228956506587 1 GO:0016411 acylglycerol O-acyltransferase activity 7/3692 31/18639 0.225806451612903 1.13998007898508 0.418228956506587 1 GO:0045505 dynein intermediate chain binding 8/3692 36/18639 0.222222222222222 1.12188515709642 0.422444107833686 1 GO:0099106 ion channel regulator activity 33/3692 160/18639 0.20625 1.04124966143012 0.428587044579087 1 GO:0030544 Hsp70 protein binding 11/3692 51/18639 0.215686274509804 1.08888853482888 0.430692477650877 1 GO:0000995 RNA polymerase III general transcription initiation factor activity 3/3692 12/18639 0.25 1.26212080173348 0.434857665844912 1 GO:0005049 nuclear export signal receptor activity 3/3692 12/18639 0.25 1.26212080173348 0.434857665844912 1 GO:0005078 MAP-kinase scaffold activity 3/3692 12/18639 0.25 1.26212080173348 0.434857665844912 1 GO:0015269 calcium-activated potassium channel activity 3/3692 12/18639 0.25 1.26212080173348 0.434857665844912 1 GO:0016840 carbon-nitrogen lyase activity 3/3692 12/18639 0.25 1.26212080173348 0.434857665844912 1 GO:0035197 siRNA binding 3/3692 12/18639 0.25 1.26212080173348 0.434857665844912 1 GO:0035251 UDP-glucosyltransferase activity 3/3692 12/18639 0.25 1.26212080173348 0.434857665844912 1 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 3/3692 12/18639 0.25 1.26212080173348 0.434857665844912 1 GO:0141221 histone deacetylase activity, hydrolytic mechanism 3/3692 12/18639 0.25 1.26212080173348 0.434857665844912 1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 18/3692 86/18639 0.209302325581395 1.05665927586989 0.439289599979486 1 GO:0008429 phosphatidylethanolamine binding 4/3692 17/18639 0.235294117647059 1.18787840163151 0.443091792527898 1 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 4/3692 17/18639 0.235294117647059 1.18787840163151 0.443091792527898 1 GO:0017110 nucleoside diphosphate phosphatase activity 4/3692 17/18639 0.235294117647059 1.18787840163151 0.443091792527898 1 GO:0032183 SUMO binding 4/3692 17/18639 0.235294117647059 1.18787840163151 0.443091792527898 1 GO:0008093 cytoskeletal anchor activity 5/3692 22/18639 0.227272727272727 1.14738254703043 0.448016569161985 1 GO:0031683 G-protein beta/gamma-subunit complex binding 5/3692 22/18639 0.227272727272727 1.14738254703043 0.448016569161985 1 GO:0061133 endopeptidase activator activity 5/3692 22/18639 0.227272727272727 1.14738254703043 0.448016569161985 1 GO:0008378 galactosyltransferase activity 7/3692 32/18639 0.21875 1.10435570151679 0.453593914322608 1 GO:0042393 histone binding 50/3692 247/18639 0.202429149797571 1.02196016334695 0.457028621432636 1 GO:0005516 calmodulin binding 42/3692 207/18639 0.202898550724638 1.02432992604456 0.458431356738797 1 GO:0019783 ubiquitin-like protein peptidase activity 26/3692 127/18639 0.204724409448819 1.03354774315182 0.460601305544707 1 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 25/3692 122/18639 0.204918032786885 1.03452524732252 0.460671653350978 1 GO:0043178 alcohol binding 19/3692 92/18639 0.206521739130435 1.04262153186679 0.460711549994125 1 GO:0051213 dioxygenase activity 19/3692 93/18639 0.204301075268817 1.03141054765316 0.481395280178833 1 GO:0051219 phosphoprotein binding 19/3692 93/18639 0.204301075268817 1.03141054765316 0.481395280178833 1 GO:0001540 amyloid-beta binding 17/3692 83/18639 0.204819277108434 1.03402668093827 0.482399509600574 1 GO:0043539 protein serine/threonine kinase activator activity 15/3692 73/18639 0.205479452054795 1.03735956306861 0.483460235331176 1 GO:0016251 RNA polymerase II general transcription initiation factor activity 11/3692 53/18639 0.207547169811321 1.04779840143911 0.485793398738275 1 GO:0034212 protein N-acetyltransferase activity 11/3692 53/18639 0.207547169811321 1.04779840143911 0.485793398738275 1 GO:1901505 carbohydrate derivative transmembrane transporter activity 11/3692 53/18639 0.207547169811321 1.04779840143911 0.485793398738275 1 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 9/3692 43/18639 0.209302325581395 1.05665927586989 0.487093159238853 1 GO:0048156 tau protein binding 9/3692 43/18639 0.209302325581395 1.05665927586989 0.487093159238853 1 GO:0140311 protein sequestering activity 7/3692 33/18639 0.212121212121212 1.07089037722841 0.488499943933014 1 GO:0061135 endopeptidase regulator activity 37/3692 184/18639 0.201086956521739 1.01518412313345 0.488699681157276 1 GO:0003887 DNA-directed DNA polymerase activity 5/3692 23/18639 0.217391304347826 1.09749634933346 0.489997178339109 1 GO:0043274 phospholipase binding 5/3692 23/18639 0.217391304347826 1.09749634933346 0.489997178339109 1 GO:0003746 translation elongation factor activity 4/3692 18/18639 0.222222222222222 1.12188515709642 0.49072616080628 1 GO:0008308 voltage-gated monoatomic anion channel activity 4/3692 18/18639 0.222222222222222 1.12188515709642 0.49072616080628 1 GO:0015172 acidic amino acid transmembrane transporter activity 4/3692 18/18639 0.222222222222222 1.12188515709642 0.49072616080628 1 GO:0017075 syntaxin-1 binding 4/3692 18/18639 0.222222222222222 1.12188515709642 0.49072616080628 1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 3/3692 13/18639 0.230769230769231 1.16503458621552 0.491290586347965 1 GO:0005172 vascular endothelial growth factor receptor binding 3/3692 13/18639 0.230769230769231 1.16503458621552 0.491290586347965 1 GO:0005542 folic acid binding 3/3692 13/18639 0.230769230769231 1.16503458621552 0.491290586347965 1 GO:0039706 co-receptor binding 3/3692 13/18639 0.230769230769231 1.16503458621552 0.491290586347965 1 GO:0045159 myosin II binding 3/3692 13/18639 0.230769230769231 1.16503458621552 0.491290586347965 1 GO:0046975 histone H3K36 methyltransferase activity 3/3692 13/18639 0.230769230769231 1.16503458621552 0.491290586347965 1 GO:0089720 caspase binding 3/3692 13/18639 0.230769230769231 1.16503458621552 0.491290586347965 1 GO:0030295 protein kinase activator activity 28/3692 139/18639 0.201438848920863 1.01696064600108 0.494319264161366 1 GO:0016410 N-acyltransferase activity 19/3692 94/18639 0.202127659574468 1.02043809501856 0.501963602599091 1 GO:0004721 phosphoprotein phosphatase activity 35/3692 175/18639 0.2 1.00969664138678 0.504916813538691 1 GO:0070063 RNA polymerase binding 12/3692 59/18639 0.203389830508475 1.02681014378317 0.511138735538115 1 GO:0008376 acetylgalactosaminyltransferase activity 7/3692 34/18639 0.205882352941176 1.03939360142757 0.522713289365106 1 GO:0016831 carboxy-lyase activity 7/3692 34/18639 0.205882352941176 1.03939360142757 0.522713289365106 1 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 7/3692 34/18639 0.205882352941176 1.03939360142757 0.522713289365106 1 GO:0003785 actin monomer binding 6/3692 29/18639 0.206896551724138 1.04451376695184 0.526298729315179 1 GO:0035250 UDP-galactosyltransferase activity 6/3692 29/18639 0.206896551724138 1.04451376695184 0.526298729315179 1 GO:0004622 lysophospholipase activity 5/3692 24/18639 0.208333333333333 1.0517673347779 0.530750904141819 1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 4/3692 19/18639 0.210526315789474 1.06283856988082 0.536566278189949 1 GO:0008574 plus-end-directed microtubule motor activity 4/3692 19/18639 0.210526315789474 1.06283856988082 0.536566278189949 1 GO:0042800 histone H3K4 methyltransferase activity 4/3692 19/18639 0.210526315789474 1.06283856988082 0.536566278189949 1 GO:1990380 K48-linked deubiquitinase activity 4/3692 19/18639 0.210526315789474 1.06283856988082 0.536566278189949 1 GO:0000149 SNARE binding 21/3692 106/18639 0.19811320754717 1.0001712013737 0.538647559613729 1 GO:0008374 O-acyltransferase activity 11/3692 55/18639 0.2 1.00969664138678 0.5396348748012 1 GO:0015605 organophosphate ester transmembrane transporter activity 10/3692 50/18639 0.2 1.00969664138678 0.542903555036806 1 GO:0022804 active transmembrane transporter activity 90/3692 457/18639 0.196936542669584 0.99423082849902 0.543881456737889 1 GO:0004065 arylsulfatase activity 3/3692 14/18639 0.214285714285714 1.08181783005727 0.544774967595114 1 GO:0005313 L-glutamate transmembrane transporter activity 3/3692 14/18639 0.214285714285714 1.08181783005727 0.544774967595114 1 GO:0008174 mRNA methyltransferase activity 3/3692 14/18639 0.214285714285714 1.08181783005727 0.544774967595114 1 GO:0008195 phosphatidate phosphatase activity 3/3692 14/18639 0.214285714285714 1.08181783005727 0.544774967595114 1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 3/3692 14/18639 0.214285714285714 1.08181783005727 0.544774967595114 1 GO:0032036 myosin heavy chain binding 3/3692 14/18639 0.214285714285714 1.08181783005727 0.544774967595114 1 GO:0034236 protein kinase A catalytic subunit binding 3/3692 14/18639 0.214285714285714 1.08181783005727 0.544774967595114 1 GO:0046030 inositol trisphosphate phosphatase activity 3/3692 14/18639 0.214285714285714 1.08181783005727 0.544774967595114 1 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 3/3692 14/18639 0.214285714285714 1.08181783005727 0.544774967595114 1 GO:1990825 sequence-specific mRNA binding 3/3692 14/18639 0.214285714285714 1.08181783005727 0.544774967595114 1 GO:0030971 receptor tyrosine kinase binding 16/3692 81/18639 0.197530864197531 0.997231250752377 0.549482106409773 1 GO:0004519 endonuclease activity 25/3692 127/18639 0.196850393700787 0.993795906876754 0.549570082775384 1 GO:0050997 quaternary ammonium group binding 8/3692 40/18639 0.2 1.00969664138678 0.55093693438034 1 GO:0140034 methylation-dependent protein binding 15/3692 76/18639 0.197368421052632 0.996411159263272 0.552168985441526 1 GO:1901681 sulfur compound binding 54/3692 275/18639 0.196363636363636 0.991338520634295 0.553083966213358 1 GO:0016229 steroid dehydrogenase activity 7/3692 35/18639 0.2 1.00969664138678 0.55602949827744 1 GO:0034061 DNA polymerase activity 7/3692 35/18639 0.2 1.00969664138678 0.55602949827744 1 GO:0019209 kinase activator activity 29/3692 148/18639 0.195945945945946 0.989229817574888 0.559114968314172 1 GO:0015215 nucleotide transmembrane transporter activity 6/3692 30/18639 0.2 1.00969664138678 0.56220685348393 1 GO:0022839 monoatomic ion-gated channel activity 6/3692 30/18639 0.2 1.00969664138678 0.56220685348393 1 GO:0031210 phosphatidylcholine binding 6/3692 30/18639 0.2 1.00969664138678 0.56220685348393 1 GO:0051721 protein phosphatase 2A binding 6/3692 30/18639 0.2 1.00969664138678 0.56220685348393 1 GO:0003707 nuclear steroid receptor activity 5/3692 25/18639 0.2 1.00969664138678 0.569969058454977 1 GO:0008139 nuclear localization sequence binding 5/3692 25/18639 0.2 1.00969664138678 0.569969058454977 1 GO:0015645 fatty acid ligase activity 5/3692 25/18639 0.2 1.00969664138678 0.569969058454977 1 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 5/3692 25/18639 0.2 1.00969664138678 0.569969058454977 1 GO:0120515 fatty acid-CoA ligase activity 5/3692 25/18639 0.2 1.00969664138678 0.569969058454977 1 GO:0005496 steroid binding 21/3692 108/18639 0.194444444444444 0.981649512459372 0.576410217194712 1 GO:1901981 phosphatidylinositol phosphate binding 36/3692 185/18639 0.194594594594595 0.982407542970923 0.577115306312081 1 GO:0000339 RNA cap binding 4/3692 20/18639 0.2 1.00969664138678 0.580219634871897 1 GO:0001972 retinoic acid binding 4/3692 20/18639 0.2 1.00969664138678 0.580219634871897 1 GO:0010851 cyclase regulator activity 4/3692 20/18639 0.2 1.00969664138678 0.580219634871897 1 GO:0015095 magnesium ion transmembrane transporter activity 4/3692 20/18639 0.2 1.00969664138678 0.580219634871897 1 GO:0016004 phospholipase activator activity 4/3692 20/18639 0.2 1.00969664138678 0.580219634871897 1 GO:0140939 histone H4 methyltransferase activity 4/3692 20/18639 0.2 1.00969664138678 0.580219634871897 1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 13/3692 67/18639 0.194029850746269 0.979556443136431 0.582018774055756 1 GO:0004725 protein tyrosine phosphatase activity 19/3692 98/18639 0.193877551020408 0.978787560528003 0.582087290585129 1 GO:0000993 RNA polymerase II complex binding 7/3692 36/18639 0.194444444444444 0.981649512459372 0.588274247694899 1 GO:0031005 filamin binding 3/3692 15/18639 0.2 1.00969664138678 0.594814332500277 1 GO:0033130 acetylcholine receptor binding 3/3692 15/18639 0.2 1.00969664138678 0.594814332500277 1 GO:0048531 beta-1,3-galactosyltransferase activity 3/3692 15/18639 0.2 1.00969664138678 0.594814332500277 1 GO:0050780 dopamine receptor binding 3/3692 15/18639 0.2 1.00969664138678 0.594814332500277 1 GO:0051371 muscle alpha-actinin binding 3/3692 15/18639 0.2 1.00969664138678 0.594814332500277 1 GO:0120283 protein serine/threonine kinase binding 3/3692 15/18639 0.2 1.00969664138678 0.594814332500277 1 GO:0005080 protein kinase C binding 10/3692 52/18639 0.192307692307692 0.970862155179598 0.596922356011063 1 GO:0004866 endopeptidase inhibitor activity 31/3692 161/18639 0.192546583850932 0.972068195123921 0.601700281441541 1 GO:0003777 microtubule motor activity 13/3692 68/18639 0.191176470588235 0.965151201325601 0.60518335197818 1 GO:0140223 general transcription initiation factor activity 13/3692 68/18639 0.191176470588235 0.965151201325601 0.60518335197818 1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 5/3692 26/18639 0.192307692307692 0.970862155179598 0.607409476409236 1 GO:0030507 spectrin binding 5/3692 26/18639 0.192307692307692 0.970862155179598 0.607409476409236 1 GO:0034237 protein kinase A regulatory subunit binding 5/3692 26/18639 0.192307692307692 0.970862155179598 0.607409476409236 1 GO:0043548 phosphatidylinositol 3-kinase binding 5/3692 26/18639 0.192307692307692 0.970862155179598 0.607409476409236 1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 17/3692 89/18639 0.191011235955056 0.964317017054792 0.608792346830318 1 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 17/3692 89/18639 0.191011235955056 0.964317017054792 0.608792346830318 1 GO:0042056 chemoattractant activity 8/3692 42/18639 0.19047619047619 0.961615848939793 0.610620912981734 1 GO:0043175 RNA polymerase core enzyme binding 8/3692 42/18639 0.19047619047619 0.961615848939793 0.610620912981734 1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 2/3692 10/18639 0.2 1.00969664138678 0.618426257266321 1 GO:0008140 cAMP response element binding protein binding 2/3692 10/18639 0.2 1.00969664138678 0.618426257266321 1 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/3692 10/18639 0.2 1.00969664138678 0.618426257266321 1 GO:0015187 glycine transmembrane transporter activity 2/3692 10/18639 0.2 1.00969664138678 0.618426257266321 1 GO:0019531 oxalate transmembrane transporter activity 2/3692 10/18639 0.2 1.00969664138678 0.618426257266321 1 GO:0031956 medium-chain fatty acid-CoA ligase activity 2/3692 10/18639 0.2 1.00969664138678 0.618426257266321 1 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 2/3692 10/18639 0.2 1.00969664138678 0.618426257266321 1 GO:0035374 chondroitin sulfate binding 2/3692 10/18639 0.2 1.00969664138678 0.618426257266321 1 GO:0043121 neurotrophin binding 2/3692 10/18639 0.2 1.00969664138678 0.618426257266321 1 GO:0070097 delta-catenin binding 2/3692 10/18639 0.2 1.00969664138678 0.618426257266321 1 GO:0099122 RNA polymerase II C-terminal domain binding 2/3692 10/18639 0.2 1.00969664138678 0.618426257266321 1 GO:0140999 histone H3K4 trimethyltransferase activity 2/3692 10/18639 0.2 1.00969664138678 0.618426257266321 1 GO:0141109 transporter activator activity 2/3692 10/18639 0.2 1.00969664138678 0.618426257266321 1 GO:1905394 retromer complex binding 2/3692 10/18639 0.2 1.00969664138678 0.618426257266321 1 GO:0022829 wide pore channel activity 7/3692 37/18639 0.189189189189189 0.955118444555064 0.619303254100939 1 GO:0009931 calcium-dependent protein serine/threonine kinase activity 4/3692 21/18639 0.19047619047619 0.961615848939793 0.621403894380253 1 GO:0051428 peptide hormone receptor binding 4/3692 21/18639 0.19047619047619 0.961615848939793 0.621403894380253 1 GO:0035064 methylated histone binding 14/3692 74/18639 0.189189189189189 0.955118444555064 0.6223578581039 1 GO:0004867 serine-type endopeptidase inhibitor activity 18/3692 95/18639 0.189473684210526 0.956554712892741 0.624244950176615 1 GO:0008080 N-acetyltransferase activity 13/3692 69/18639 0.188405797101449 0.951163502755664 0.627739400214494 1 GO:0140793 histone H2AXY142 phosphatase activity 17/3692 90/18639 0.188888888888889 0.953602383531961 0.62854280927539 1 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 6/3692 32/18639 0.1875 0.946590601300108 0.629800233628312 1 GO:0120015 sterol transfer activity 6/3692 32/18639 0.1875 0.946590601300108 0.629800233628312 1 GO:1902936 phosphatidylinositol bisphosphate binding 21/3692 111/18639 0.189189189189189 0.955118444555064 0.630748476077326 1 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 25/3692 132/18639 0.189393939393939 0.956152122525362 0.633630329391664 1 GO:0004712 protein serine/threonine/tyrosine kinase activity 8/3692 43/18639 0.186046511627907 0.939252689662123 0.638855828122964 1 GO:0008375 acetylglucosaminyltransferase activity 8/3692 43/18639 0.186046511627907 0.939252689662123 0.638855828122964 1 GO:0005024 transforming growth factor beta receptor activity 3/3692 16/18639 0.1875 0.946590601300108 0.641115501888326 1 GO:0005521 lamin binding 3/3692 16/18639 0.1875 0.946590601300108 0.641115501888326 1 GO:0008296 3'-5'-DNA exonuclease activity 3/3692 16/18639 0.1875 0.946590601300108 0.641115501888326 1 GO:0031435 mitogen-activated protein kinase kinase kinase binding 3/3692 16/18639 0.1875 0.946590601300108 0.641115501888326 1 GO:0140327 flippase activity 3/3692 16/18639 0.1875 0.946590601300108 0.641115501888326 1 GO:0140328 floppase activity 3/3692 16/18639 0.1875 0.946590601300108 0.641115501888326 1 GO:0004683 calcium/calmodulin-dependent protein kinase activity 5/3692 27/18639 0.185185185185185 0.934904297580354 0.642892319871569 1 GO:0016405 CoA-ligase activity 5/3692 27/18639 0.185185185185185 0.934904297580354 0.642892319871569 1 GO:0035255 ionotropic glutamate receptor binding 5/3692 27/18639 0.185185185185185 0.934904297580354 0.642892319871569 1 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 5/3692 27/18639 0.185185185185185 0.934904297580354 0.642892319871569 1 GO:0030414 peptidase inhibitor activity 32/3692 169/18639 0.189349112426035 0.955925814330681 0.642933643450824 1 GO:0016887 ATP hydrolysis activity 80/3692 417/18639 0.191846522781775 0.968533948572453 0.646101506034296 1 GO:0035254 glutamate receptor binding 9/3692 49/18639 0.183673469387755 0.927272425763372 0.656174894571264 1 GO:0005243 gap junction channel activity 4/3692 22/18639 0.181818181818182 0.917906037624348 0.659934411095424 1 GO:0019239 deaminase activity 6/3692 33/18639 0.181818181818182 0.917906037624348 0.661200298005044 1 GO:0071889 14-3-3 protein binding 6/3692 33/18639 0.181818181818182 0.917906037624348 0.661200298005044 1 GO:0070851 growth factor receptor binding 26/3692 139/18639 0.18705035971223 0.944320599858142 0.661535260834691 1 GO:0003953 NAD+ nucleosidase activity 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0004143 ATP-dependent diacylglycerol kinase activity 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0005225 volume-sensitive anion channel activity 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0008172 S-methyltransferase activity 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0008271 secondary active sulfate transmembrane transporter activity 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0008432 JUN kinase binding 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0015173 aromatic amino acid transmembrane transporter activity 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0034056 estrogen response element binding 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0034713 type I transforming growth factor beta receptor binding 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0035252 UDP-xylosyltransferase activity 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0042285 xylosyltransferase activity 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0042608 T cell receptor binding 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0070697 activin receptor binding 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0097493 structural molecule activity conferring elasticity 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/3692 11/18639 0.181818181818182 0.917906037624348 0.672250622080318 1 GO:0008234 cysteine-type peptidase activity 35/3692 187/18639 0.18716577540107 0.944903274025064 0.675101092569938 1 GO:0019789 SUMO transferase activity 5/3692 28/18639 0.178571428571429 0.901514858381056 0.676294563501753 1 GO:0036408 histone H3K14 acetyltransferase activity 5/3692 28/18639 0.178571428571429 0.901514858381056 0.676294563501753 1 GO:0046966 nuclear thyroid hormone receptor binding 5/3692 28/18639 0.178571428571429 0.901514858381056 0.676294563501753 1 GO:0051019 mitogen-activated protein kinase binding 5/3692 28/18639 0.178571428571429 0.901514858381056 0.676294563501753 1 GO:0051959 dynein light intermediate chain binding 5/3692 28/18639 0.178571428571429 0.901514858381056 0.676294563501753 1 GO:0032813 tumor necrosis factor receptor superfamily binding 9/3692 50/18639 0.18 0.908726977248104 0.681039334956876 1 GO:0004659 prenyltransferase activity 3/3692 17/18639 0.176470588235294 0.890908801223631 0.683549153894132 1 GO:0008484 sulfuric ester hydrolase activity 3/3692 17/18639 0.176470588235294 0.890908801223631 0.683549153894132 1 GO:0030548 acetylcholine receptor regulator activity 3/3692 17/18639 0.176470588235294 0.890908801223631 0.683549153894132 1 GO:0045236 CXCR chemokine receptor binding 3/3692 17/18639 0.176470588235294 0.890908801223631 0.683549153894132 1 GO:0046965 nuclear retinoid X receptor binding 3/3692 17/18639 0.176470588235294 0.890908801223631 0.683549153894132 1 GO:0140597 protein carrier chaperone 35/3692 188/18639 0.186170212765957 0.939877192780249 0.687899399912805 1 GO:0140303 intramembrane lipid transporter activity 8/3692 45/18639 0.177777777777778 0.89750812567714 0.691688448392889 1 GO:0019838 growth factor binding 25/3692 136/18639 0.183823529411765 0.928030001274616 0.69522405420567 1 GO:0070577 lysine-acetylated histone binding 4/3692 23/18639 0.173913043478261 0.877997079466767 0.695710670623069 1 GO:0030165 PDZ domain binding 15/3692 83/18639 0.180722891566265 0.912376483180827 0.696798472095721 1 GO:0001221 transcription coregulator binding 21/3692 115/18639 0.182608695652174 0.921896933440105 0.697670614436213 1 GO:0042054 histone methyltransferase activity 12/3692 67/18639 0.17910447761194 0.904205947510551 0.698924355896857 1 GO:0050840 extracellular matrix binding 12/3692 67/18639 0.17910447761194 0.904205947510551 0.698924355896857 1 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 7/3692 40/18639 0.175 0.883484561213434 0.704081778863293 1 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 7/3692 40/18639 0.175 0.883484561213434 0.704081778863293 1 GO:0071949 FAD binding 7/3692 40/18639 0.175 0.883484561213434 0.704081778863293 1 GO:0010484 histone H3 acetyltransferase activity 5/3692 29/18639 0.172413793103448 0.870428139126536 0.707543695623955 1 GO:0010485 histone H4 acetyltransferase activity 6/3692 35/18639 0.171428571428571 0.865454264045813 0.718775379493498 1 GO:0000340 RNA 7-methylguanosine cap binding 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0003720 telomerase activity 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0004000 adenosine deaminase activity 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0005025 transforming growth factor beta receptor activity, type I 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0005026 transforming growth factor beta receptor activity, type II 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0005165 neurotrophin receptor binding 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0005247 voltage-gated chloride channel activity 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0016208 AMP binding 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0016273 arginine N-methyltransferase activity 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0016274 protein-arginine N-methyltransferase activity 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0016361 activin receptor activity, type I 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0016362 activin receptor activity, type II 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0016801 hydrolase activity, acting on ether bonds 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0016803 ether hydrolase activity 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0017002 activin receptor activity 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0034452 dynactin binding 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0070410 co-SMAD binding 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/3692 12/18639 0.166666666666667 0.841413867822319 0.719729213327399 1 GO:0000900 mRNA regulatory element binding translation repressor activity 3/3692 18/18639 0.166666666666667 0.841413867822319 0.722113752511702 1 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 3/3692 18/18639 0.166666666666667 0.841413867822319 0.722113752511702 1 GO:0008525 phosphatidylcholine transporter activity 3/3692 18/18639 0.166666666666667 0.841413867822319 0.722113752511702 1 GO:0017128 phospholipid scramblase activity 3/3692 18/18639 0.166666666666667 0.841413867822319 0.722113752511702 1 GO:0031690 adrenergic receptor binding 3/3692 18/18639 0.166666666666667 0.841413867822319 0.722113752511702 1 GO:0099602 neurotransmitter receptor regulator activity 3/3692 18/18639 0.166666666666667 0.841413867822319 0.722113752511702 1 GO:0050431 transforming growth factor beta binding 4/3692 24/18639 0.166666666666667 0.841413867822319 0.728702623919319 1 GO:0060229 lipase activator activity 4/3692 24/18639 0.166666666666667 0.841413867822319 0.728702623919319 1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 4/3692 24/18639 0.166666666666667 0.841413867822319 0.728702623919319 1 GO:0140033 acetylation-dependent protein binding 4/3692 24/18639 0.166666666666667 0.841413867822319 0.728702623919319 1 GO:0042287 MHC protein binding 7/3692 41/18639 0.170731707317073 0.861936157281399 0.729364630051262 1 GO:0048029 monosaccharide binding 13/3692 74/18639 0.175675675675676 0.886895698515417 0.729825638868109 1 GO:0008106 alcohol dehydrogenase (NADP+) activity 5/3692 30/18639 0.166666666666667 0.841413867822319 0.736611064051961 1 GO:0033612 receptor serine/threonine kinase binding 5/3692 30/18639 0.166666666666667 0.841413867822319 0.736611064051961 1 GO:0043995 histone H4K5 acetyltransferase activity 5/3692 30/18639 0.166666666666667 0.841413867822319 0.736611064051961 1 GO:0043996 histone H4K8 acetyltransferase activity 5/3692 30/18639 0.166666666666667 0.841413867822319 0.736611064051961 1 GO:0043997 histone H4K12 acetyltransferase activity 5/3692 30/18639 0.166666666666667 0.841413867822319 0.736611064051961 1 GO:0070566 adenylyltransferase activity 5/3692 30/18639 0.166666666666667 0.841413867822319 0.736611064051961 1 GO:0098918 structural constituent of synapse 5/3692 30/18639 0.166666666666667 0.841413867822319 0.736611064051961 1 GO:0005504 fatty acid binding 8/3692 47/18639 0.170212765957447 0.859316290541942 0.739338003532371 1 GO:0061733 protein-lysine-acetyltransferase activity 8/3692 47/18639 0.170212765957447 0.859316290541942 0.739338003532371 1 GO:0004033 aldo-keto reductase (NADPH) activity 6/3692 36/18639 0.166666666666667 0.841413867822319 0.744875605853218 1 GO:0004869 cysteine-type endopeptidase inhibitor activity 6/3692 36/18639 0.166666666666667 0.841413867822319 0.744875605853218 1 GO:0003725 double-stranded RNA binding 13/3692 75/18639 0.173333333333333 0.875070422535211 0.747893760461749 1 GO:0005246 calcium channel regulator activity 9/3692 53/18639 0.169811320754717 0.857289601177457 0.748740932019729 1 GO:0051018 protein kinase A binding 9/3692 53/18639 0.169811320754717 0.857289601177457 0.748740932019729 1 GO:0004520 DNA endonuclease activity 7/3692 42/18639 0.166666666666667 0.841413867822319 0.753113373465167 1 GO:0019894 kinesin binding 7/3692 42/18639 0.166666666666667 0.841413867822319 0.753113373465167 1 GO:0051879 Hsp90 protein binding 7/3692 42/18639 0.166666666666667 0.841413867822319 0.753113373465167 1 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 3/3692 19/18639 0.157894736842105 0.797128927410618 0.756903903947031 1 GO:0008301 DNA binding, bending 3/3692 19/18639 0.157894736842105 0.797128927410618 0.756903903947031 1 GO:0022840 leak channel activity 3/3692 19/18639 0.157894736842105 0.797128927410618 0.756903903947031 1 GO:0022842 narrow pore channel activity 3/3692 19/18639 0.157894736842105 0.797128927410618 0.756903903947031 1 GO:0030506 ankyrin binding 3/3692 19/18639 0.157894736842105 0.797128927410618 0.756903903947031 1 GO:0031420 alkali metal ion binding 3/3692 19/18639 0.157894736842105 0.797128927410618 0.756903903947031 1 GO:0043395 heparan sulfate proteoglycan binding 3/3692 19/18639 0.157894736842105 0.797128927410618 0.756903903947031 1 GO:0001618 virus receptor activity 14/3692 81/18639 0.172839506172839 0.87257734440833 0.756972353091197 1 GO:0015459 potassium channel regulator activity 10/3692 59/18639 0.169491525423729 0.855675119819307 0.757621573071824 1 GO:0008483 transaminase activity 4/3692 25/18639 0.16 0.807757313109426 0.75893758876967 1 GO:0042974 nuclear retinoic acid receptor binding 4/3692 25/18639 0.16 0.807757313109426 0.75893758876967 1 GO:0120020 cholesterol transfer activity 4/3692 25/18639 0.16 0.807757313109426 0.75893758876967 1 GO:0003964 RNA-directed DNA polymerase activity 2/3692 13/18639 0.153846153846154 0.776689724143679 0.761263509141841 1 GO:0008417 fucosyltransferase activity 2/3692 13/18639 0.153846153846154 0.776689724143679 0.761263509141841 1 GO:0017154 semaphorin receptor activity 2/3692 13/18639 0.153846153846154 0.776689724143679 0.761263509141841 1 GO:0030955 potassium ion binding 2/3692 13/18639 0.153846153846154 0.776689724143679 0.761263509141841 1 GO:0031432 titin binding 2/3692 13/18639 0.153846153846154 0.776689724143679 0.761263509141841 1 GO:0035673 oligopeptide transmembrane transporter activity 2/3692 13/18639 0.153846153846154 0.776689724143679 0.761263509141841 1 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 2/3692 13/18639 0.153846153846154 0.776689724143679 0.761263509141841 1 GO:0061459 L-arginine transmembrane transporter activity 2/3692 13/18639 0.153846153846154 0.776689724143679 0.761263509141841 1 GO:0070123 transforming growth factor beta receptor activity, type III 2/3692 13/18639 0.153846153846154 0.776689724143679 0.761263509141841 1 GO:0070700 BMP receptor binding 2/3692 13/18639 0.153846153846154 0.776689724143679 0.761263509141841 1 GO:0140333 glycerophospholipid flippase activity 2/3692 13/18639 0.153846153846154 0.776689724143679 0.761263509141841 1 GO:0140410 monoatomic cation:bicarbonate symporter activity 2/3692 13/18639 0.153846153846154 0.776689724143679 0.761263509141841 1 GO:0140666 annealing activity 2/3692 13/18639 0.153846153846154 0.776689724143679 0.761263509141841 1 GO:1901338 catecholamine binding 2/3692 13/18639 0.153846153846154 0.776689724143679 0.761263509141841 1 GO:0042578 phosphoric ester hydrolase activity 67/3692 363/18639 0.184573002754821 0.93181370486108 0.761842902249087 1 GO:0005164 tumor necrosis factor receptor binding 5/3692 31/18639 0.161290322580645 0.81427148498934 0.763505201608397 1 GO:0017147 Wnt-protein binding 5/3692 31/18639 0.161290322580645 0.81427148498934 0.763505201608397 1 GO:0030527 structural constituent of chromatin 17/3692 98/18639 0.173469387755102 0.87575729099874 0.766747894064306 1 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 9/3692 54/18639 0.166666666666667 0.841413867822319 0.768943234263402 1 GO:0140272 exogenous protein binding 14/3692 82/18639 0.170731707317073 0.861936157281399 0.773252036032487 1 GO:0101005 deubiquitinase activity 20/3692 115/18639 0.173913043478261 0.877997079466767 0.776344956789569 1 GO:0005160 transforming growth factor beta receptor binding 4/3692 26/18639 0.153846153846154 0.776689724143679 0.786488154653385 1 GO:0030247 polysaccharide binding 4/3692 26/18639 0.153846153846154 0.776689724143679 0.786488154653385 1 GO:0070412 R-SMAD binding 4/3692 26/18639 0.153846153846154 0.776689724143679 0.786488154653385 1 GO:0030742 GTP-dependent protein binding 3/3692 20/18639 0.15 0.757272481040087 0.788083480842643 1 GO:0052745 inositol phosphate phosphatase activity 3/3692 20/18639 0.15 0.757272481040087 0.788083480842643 1 GO:0016758 hexosyltransferase activity 35/3692 197/18639 0.177664974619289 0.896938640825822 0.790047219402942 1 GO:0140297 DNA-binding transcription factor binding 90/3692 488/18639 0.184426229508197 0.931072722590271 0.794148821959372 1 GO:0030547 signaling receptor inhibitor activity 7/3692 44/18639 0.159090909090909 0.803167782921304 0.7960331713532 1 GO:0031406 carboxylic acid binding 33/3692 187/18639 0.176470588235294 0.890908801223631 0.797287439195152 1 GO:0005161 platelet-derived growth factor receptor binding 2/3692 14/18639 0.142857142857143 0.721211886704844 0.797344932732963 1 GO:0008191 metalloendopeptidase inhibitor activity 2/3692 14/18639 0.142857142857143 0.721211886704844 0.797344932732963 1 GO:0030983 mismatched DNA binding 2/3692 14/18639 0.142857142857143 0.721211886704844 0.797344932732963 1 GO:0031404 chloride ion binding 2/3692 14/18639 0.142857142857143 0.721211886704844 0.797344932732963 1 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 2/3692 14/18639 0.142857142857143 0.721211886704844 0.797344932732963 1 GO:0042813 Wnt receptor activity 2/3692 14/18639 0.142857142857143 0.721211886704844 0.797344932732963 1 GO:0061665 SUMO ligase activity 2/3692 14/18639 0.142857142857143 0.721211886704844 0.797344932732963 1 GO:0070742 C2H2 zinc finger domain binding 2/3692 14/18639 0.142857142857143 0.721211886704844 0.797344932732963 1 GO:0071933 Arp2/3 complex binding 2/3692 14/18639 0.142857142857143 0.721211886704844 0.797344932732963 1 GO:0098821 BMP receptor activity 2/3692 14/18639 0.142857142857143 0.721211886704844 0.797344932732963 1 GO:1990782 protein tyrosine kinase binding 20/3692 117/18639 0.170940170940171 0.862988582381865 0.802086431317693 1 GO:0030170 pyridoxal phosphate binding 9/3692 56/18639 0.160714285714286 0.81136337254295 0.805801887185628 1 GO:0005178 integrin binding 28/3692 161/18639 0.173913043478261 0.877997079466767 0.807148130647093 1 GO:0015179 L-amino acid transmembrane transporter activity 10/3692 62/18639 0.161290322580645 0.81427148498934 0.810878860169882 1 GO:0140416 transcription regulator inhibitor activity 5/3692 33/18639 0.151515151515152 0.76492169802029 0.810955574231633 1 GO:0005385 zinc ion transmembrane transporter activity 4/3692 27/18639 0.148148148148148 0.747923438064283 0.811461343311092 1 GO:0008266 poly(U) RNA binding 4/3692 27/18639 0.148148148148148 0.747923438064283 0.811461343311092 1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 4/3692 27/18639 0.148148148148148 0.747923438064283 0.811461343311092 1 GO:0046332 SMAD binding 13/3692 79/18639 0.164556962025316 0.830763059368871 0.811939775757209 1 GO:0000217 DNA secondary structure binding 6/3692 39/18639 0.153846153846154 0.776689724143679 0.812519214256208 1 GO:0005319 lipid transporter activity 31/3692 178/18639 0.174157303370787 0.87923022143231 0.814804443510351 1 GO:0001846 opsonin binding 3/3692 21/18639 0.142857142857143 0.721211886704844 0.815863411919708 1 GO:0019200 carbohydrate kinase activity 3/3692 21/18639 0.142857142857143 0.721211886704844 0.815863411919708 1 GO:0035613 RNA stem-loop binding 3/3692 21/18639 0.142857142857143 0.721211886704844 0.815863411919708 1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 3/3692 21/18639 0.142857142857143 0.721211886704844 0.815863411919708 1 GO:0043177 organic acid binding 33/3692 189/18639 0.174603174603175 0.881481194861476 0.816626850945408 1 GO:0016597 amino acid binding 8/3692 51/18639 0.156862745098039 0.791918934421006 0.818673817559153 1 GO:0003678 DNA helicase activity 12/3692 74/18639 0.162162162162162 0.818672952475769 0.820976366418635 1 GO:0015932 nucleobase-containing compound transmembrane transporter activity 9/3692 57/18639 0.157894736842105 0.797128927410618 0.822492683859906 1 GO:0070279 vitamin B6 binding 9/3692 57/18639 0.157894736842105 0.797128927410618 0.822492683859906 1 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 22/3692 130/18639 0.169230769230769 0.854358696558047 0.825464058933537 1 GO:0004089 carbonate dehydratase activity 2/3692 15/18639 0.133333333333333 0.673131094257855 0.828503486614914 1 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/3692 15/18639 0.133333333333333 0.673131094257855 0.828503486614914 1 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/3692 15/18639 0.133333333333333 0.673131094257855 0.828503486614914 1 GO:0008242 omega peptidase activity 2/3692 15/18639 0.133333333333333 0.673131094257855 0.828503486614914 1 GO:0010181 FMN binding 2/3692 15/18639 0.133333333333333 0.673131094257855 0.828503486614914 1 GO:0015116 sulfate transmembrane transporter activity 2/3692 15/18639 0.133333333333333 0.673131094257855 0.828503486614914 1 GO:0015929 hexosaminidase activity 2/3692 15/18639 0.133333333333333 0.673131094257855 0.828503486614914 1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 2/3692 15/18639 0.133333333333333 0.673131094257855 0.828503486614914 1 GO:0030553 cGMP binding 2/3692 15/18639 0.133333333333333 0.673131094257855 0.828503486614914 1 GO:0050660 flavin adenine dinucleotide binding 14/3692 86/18639 0.162790697674419 0.821846103454358 0.830742182201504 1 GO:0032451 demethylase activity 6/3692 40/18639 0.15 0.757272481040087 0.831655232266722 1 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 5/3692 34/18639 0.147058823529412 0.742424001019693 0.83165893434558 1 GO:0052866 phosphatidylinositol phosphate phosphatase activity 5/3692 34/18639 0.147058823529412 0.742424001019693 0.83165893434558 1 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 7/3692 46/18639 0.152173913043478 0.768247444533421 0.833037711006896 1 GO:0017116 single-stranded DNA helicase activity 9/3692 58/18639 0.155172413793103 0.783385325213883 0.838060242370615 1 GO:0015101 organic cation transmembrane transporter activity 13/3692 81/18639 0.160493827160494 0.810250391236307 0.839092047580045 1 GO:0008970 phospholipase A1 activity 3/3692 22/18639 0.136363636363636 0.688429528218261 0.84048378047091 1 GO:0032931 histone H3K56 acetyltransferase activity 3/3692 22/18639 0.136363636363636 0.688429528218261 0.84048378047091 1 GO:0043992 histone H3K9 acetyltransferase activity 3/3692 22/18639 0.136363636363636 0.688429528218261 0.84048378047091 1 GO:0043993 histone H3K18 acetyltransferase activity 3/3692 22/18639 0.136363636363636 0.688429528218261 0.84048378047091 1 GO:0043994 histone H3K23 acetyltransferase activity 3/3692 22/18639 0.136363636363636 0.688429528218261 0.84048378047091 1 GO:0043999 histone H2AK5 acetyltransferase activity 3/3692 22/18639 0.136363636363636 0.688429528218261 0.84048378047091 1 GO:0044012 histone H2AK9 acetyltransferase activity 3/3692 22/18639 0.136363636363636 0.688429528218261 0.84048378047091 1 GO:0044014 histone H2BK5 acetyltransferase activity 3/3692 22/18639 0.136363636363636 0.688429528218261 0.84048378047091 1 GO:0044015 histone H2BK12 acetyltransferase activity 3/3692 22/18639 0.136363636363636 0.688429528218261 0.84048378047091 1 GO:0044016 histone H3K4 acetyltransferase activity 3/3692 22/18639 0.136363636363636 0.688429528218261 0.84048378047091 1 GO:0044017 histone H3K27 acetyltransferase activity 3/3692 22/18639 0.136363636363636 0.688429528218261 0.84048378047091 1 GO:0044018 histone H3K36 acetyltransferase activity 3/3692 22/18639 0.136363636363636 0.688429528218261 0.84048378047091 1 GO:0050321 tau-protein kinase activity 3/3692 22/18639 0.136363636363636 0.688429528218261 0.84048378047091 1 GO:0140908 histone H3K122 acetyltransferase activity 3/3692 22/18639 0.136363636363636 0.688429528218261 0.84048378047091 1 GO:0016922 nuclear receptor binding 23/3692 137/18639 0.167883211678832 0.847555574886715 0.840905651839919 1 GO:0004536 DNA nuclease activity 10/3692 64/18639 0.15625 0.788825501083424 0.841183789343744 1 GO:0015175 neutral L-amino acid transmembrane transporter activity 6/3692 41/18639 0.146341463414634 0.738802420526914 0.849190764075086 1 GO:0004879 nuclear receptor activity 9/3692 59/18639 0.152542372881356 0.770107607837376 0.852539202844398 1 GO:0005416 amino acid:monoatomic cation symporter activity 4/3692 29/18639 0.137931034482759 0.696342511301229 0.854220411037507 1 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/3692 16/18639 0.125 0.631060400866739 0.855273198718712 1 GO:0015385 sodium:proton antiporter activity 2/3692 16/18639 0.125 0.631060400866739 0.855273198718712 1 GO:0015562 efflux transmembrane transporter activity 2/3692 16/18639 0.125 0.631060400866739 0.855273198718712 1 GO:0019841 retinol binding 2/3692 16/18639 0.125 0.631060400866739 0.855273198718712 1 GO:0022841 potassium ion leak channel activity 2/3692 16/18639 0.125 0.631060400866739 0.855273198718712 1 GO:0022858 alanine transmembrane transporter activity 2/3692 16/18639 0.125 0.631060400866739 0.855273198718712 1 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/3692 16/18639 0.125 0.631060400866739 0.855273198718712 1 GO:0005212 structural constituent of eye lens 3/3692 23/18639 0.130434782608696 0.658497809600075 0.862199746948087 1 GO:0005283 amino acid:sodium symporter activity 3/3692 23/18639 0.130434782608696 0.658497809600075 0.862199746948087 1 GO:0044013 histone H2B acetyltransferase activity 3/3692 23/18639 0.130434782608696 0.658497809600075 0.862199746948087 1 GO:0099186 structural constituent of postsynapse 3/3692 23/18639 0.130434782608696 0.658497809600075 0.862199746948087 1 GO:0008194 UDP-glycosyltransferase activity 24/3692 145/18639 0.16551724137931 0.835611013561475 0.863749111519646 1 GO:0004402 histone acetyltransferase activity 6/3692 42/18639 0.142857142857143 0.721211886704844 0.865203662510073 1 GO:0098531 ligand-modulated transcription factor activity 9/3692 60/18639 0.15 0.757272481040087 0.86596908884505 1 GO:0003727 single-stranded RNA binding 14/3692 89/18639 0.157303370786517 0.794143425809829 0.866127568731645 1 GO:0140097 catalytic activity, acting on DNA 59/3692 336/18639 0.175595238095238 0.886489610741371 0.867850740856227 1 GO:0035591 signaling adaptor activity 21/3692 129/18639 0.162790697674419 0.821846103454358 0.870121685925553 1 GO:0008187 poly-pyrimidine tract binding 4/3692 30/18639 0.133333333333333 0.673131094257855 0.872314156727591 1 GO:0048019 receptor antagonist activity 4/3692 30/18639 0.133333333333333 0.673131094257855 0.872314156727591 1 GO:0015297 antiporter activity 22/3692 135/18639 0.162962962962963 0.822715781870711 0.873585094078507 1 GO:0046906 tetrapyrrole binding 25/3692 152/18639 0.164473684210526 0.830342632719393 0.875679995564579 1 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/3692 17/18639 0.117647058823529 0.593939200815754 0.878169738028656 1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/3692 17/18639 0.117647058823529 0.593939200815754 0.878169738028656 1 GO:0008569 minus-end-directed microtubule motor activity 2/3692 17/18639 0.117647058823529 0.593939200815754 0.878169738028656 1 GO:0015278 intracellularly gated calcium channel activity 2/3692 17/18639 0.117647058823529 0.593939200815754 0.878169738028656 1 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/3692 17/18639 0.117647058823529 0.593939200815754 0.878169738028656 1 GO:0016805 dipeptidase activity 2/3692 17/18639 0.117647058823529 0.593939200815754 0.878169738028656 1 GO:0036041 long-chain fatty acid binding 2/3692 17/18639 0.117647058823529 0.593939200815754 0.878169738028656 1 GO:0070492 oligosaccharide binding 2/3692 17/18639 0.117647058823529 0.593939200815754 0.878169738028656 1 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 61/3692 349/18639 0.174785100286533 0.882399643618821 0.880102806125963 1 GO:0005315 phosphate transmembrane transporter activity 3/3692 24/18639 0.125 0.631060400866739 0.881270764523625 1 GO:0030552 cAMP binding 3/3692 24/18639 0.125 0.631060400866739 0.881270764523625 1 GO:0035035 histone acetyltransferase binding 3/3692 24/18639 0.125 0.631060400866739 0.881270764523625 1 GO:0043998 histone H2A acetyltransferase activity 3/3692 24/18639 0.125 0.631060400866739 0.881270764523625 1 GO:0050699 WW domain binding 3/3692 24/18639 0.125 0.631060400866739 0.881270764523625 1 GO:0043394 proteoglycan binding 5/3692 37/18639 0.135135135135135 0.682227460396474 0.882867916514931 1 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 30/3692 181/18639 0.165745856353591 0.836765172419985 0.88484366089603 1 GO:0031072 heat shock protein binding 21/3692 131/18639 0.16030534351145 0.809298834699329 0.886876836012484 1 GO:0005452 solute:inorganic anion antiporter activity 4/3692 31/18639 0.129032258064516 0.651417187991472 0.888434001930434 1 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0004382 GDP phosphatase activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0004935 adrenergic receptor activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0005345 purine nucleobase transmembrane transporter activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0005381 iron ion transmembrane transporter activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0008239 dipeptidyl-peptidase activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0008401 retinoic acid 4-hydroxylase activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0015279 store-operated calcium channel activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0032356 oxidized DNA binding 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0035256 G protein-coupled glutamate receptor binding 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0042166 acetylcholine binding 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0042975 peroxisome proliferator activated receptor binding 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0043208 glycosphingolipid binding 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0050308 sugar-phosphatase activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0051864 histone H3K36 demethylase activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0051880 G-quadruplex DNA binding 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0140135 mechanosensitive monoatomic cation channel activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0140940 histone H2A methyltransferase activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:1990259 histone H2AQ104 methyltransferase activity 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:1990763 arrestin family protein binding 1/3692 10/18639 0.1 0.504848320693391 0.890085453180692 1 GO:0030020 extracellular matrix structural constituent conferring tensile strength 6/3692 44/18639 0.136363636363636 0.688429528218261 0.893000579070372 1 GO:0005501 retinoid binding 5/3692 38/18639 0.131578947368421 0.664274106175515 0.896679206674818 1 GO:0019840 isoprenoid binding 5/3692 38/18639 0.131578947368421 0.664274106175515 0.896679206674818 1 GO:0000400 four-way junction DNA binding 2/3692 18/18639 0.111111111111111 0.560942578548212 0.897676736218276 1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/3692 18/18639 0.111111111111111 0.560942578548212 0.897676736218276 1 GO:0008409 5'-3' exonuclease activity 2/3692 18/18639 0.111111111111111 0.560942578548212 0.897676736218276 1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/3692 18/18639 0.111111111111111 0.560942578548212 0.897676736218276 1 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/3692 18/18639 0.111111111111111 0.560942578548212 0.897676736218276 1 GO:0034185 apolipoprotein binding 2/3692 18/18639 0.111111111111111 0.560942578548212 0.897676736218276 1 GO:0050811 GABA receptor binding 2/3692 18/18639 0.111111111111111 0.560942578548212 0.897676736218276 1 GO:0001848 complement binding 3/3692 25/18639 0.12 0.605817984832069 0.897952561217346 1 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 3/3692 25/18639 0.12 0.605817984832069 0.897952561217346 1 GO:0004222 metalloendopeptidase activity 17/3692 110/18639 0.154545454545455 0.780220131980695 0.900883657361496 1 GO:0015106 bicarbonate transmembrane transporter activity 4/3692 32/18639 0.125 0.631060400866739 0.902743804939929 1 GO:0043425 bHLH transcription factor binding 4/3692 32/18639 0.125 0.631060400866739 0.902743804939929 1 GO:0070717 poly-purine tract binding 4/3692 32/18639 0.125 0.631060400866739 0.902743804939929 1 GO:0016757 glycosyltransferase activity 45/3692 267/18639 0.168539325842697 0.850867956224816 0.90470565969618 1 GO:0004715 non-membrane spanning protein tyrosine kinase activity 6/3692 45/18639 0.133333333333333 0.673131094257855 0.90496150389843 1 GO:0000099 sulfur amino acid transmembrane transporter activity 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0001851 complement component C3b binding 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0005114 type II transforming growth factor beta receptor binding 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0005536 D-glucose binding 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0008199 ferric iron binding 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0008503 benzodiazepine receptor activity 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0015205 nucleobase transmembrane transporter activity 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0016594 glycine binding 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0019203 carbohydrate phosphatase activity 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0043855 cyclic nucleotide-activated monoatomic ion channel activity 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0048185 activin binding 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0048407 platelet-derived growth factor binding 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0140537 transcription regulator activator activity 1/3692 11/18639 0.0909090909090909 0.458953018812174 0.911868936290729 1 GO:0004529 DNA exonuclease activity 3/3692 26/18639 0.115384615384615 0.582517293107759 0.912491396856123 1 GO:0008143 poly(A) binding 3/3692 26/18639 0.115384615384615 0.582517293107759 0.912491396856123 1 GO:0050681 nuclear androgen receptor binding 3/3692 26/18639 0.115384615384615 0.582517293107759 0.912491396856123 1 GO:0051139 metal cation:proton antiporter activity 3/3692 26/18639 0.115384615384615 0.582517293107759 0.912491396856123 1 GO:0070006 metalloaminopeptidase activity 3/3692 26/18639 0.115384615384615 0.582517293107759 0.912491396856123 1 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 7/3692 52/18639 0.134615384615385 0.679603508625719 0.91287678692733 1 GO:0030159 signaling receptor complex adaptor activity 7/3692 52/18639 0.134615384615385 0.679603508625719 0.91287678692733 1 GO:0008013 beta-catenin binding 16/3692 106/18639 0.150943396226415 0.762035201046628 0.914186159805 1 GO:0005229 intracellularly calcium-gated chloride channel activity 2/3692 19/18639 0.105263157894737 0.531419284940412 0.914238245897246 1 GO:0016918 retinal binding 2/3692 19/18639 0.105263157894737 0.531419284940412 0.914238245897246 1 GO:0141147 intracellularly calcium-gated channel activity 2/3692 19/18639 0.105263157894737 0.531419284940412 0.914238245897246 1 GO:0030331 nuclear estrogen receptor binding 5/3692 40/18639 0.125 0.631060400866739 0.920112882416917 1 GO:0070888 E-box binding 8/3692 59/18639 0.135593220338983 0.684540095855446 0.920271906941065 1 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/3692 27/18639 0.111111111111111 0.560942578548212 0.925120153549252 1 GO:0023026 MHC class II protein complex binding 3/3692 27/18639 0.111111111111111 0.560942578548212 0.925120153549252 1 GO:0001784 phosphotyrosine residue binding 6/3692 47/18639 0.127659574468085 0.644487217906457 0.925454694249315 1 GO:0061749 forked DNA-dependent helicase activity 6/3692 47/18639 0.127659574468085 0.644487217906457 0.925454694249315 1 GO:0140938 histone H3 methyltransferase activity 6/3692 47/18639 0.127659574468085 0.644487217906457 0.925454694249315 1 GO:1990518 single-stranded 3'-5' DNA helicase activity 6/3692 47/18639 0.127659574468085 0.644487217906457 0.925454694249315 1 GO:0005506 iron ion binding 24/3692 154/18639 0.155844155844156 0.786776603678012 0.925924368157379 1 GO:0051427 hormone receptor binding 4/3692 34/18639 0.117647058823529 0.593939200815754 0.926570292716105 1 GO:0004843 cysteine-type deubiquitinase activity 16/3692 108/18639 0.148148148148148 0.747923438064283 0.927439112316136 1 GO:0001614 purinergic nucleotide receptor activity 2/3692 20/18639 0.1 0.504848320693391 0.928255442014424 1 GO:0016502 nucleotide receptor activity 2/3692 20/18639 0.1 0.504848320693391 0.928255442014424 1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/3692 20/18639 0.1 0.504848320693391 0.928255442014424 1 GO:0003995 acyl-CoA dehydrogenase activity 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0004032 aldose reductase (NADPH) activity 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0004126 cytidine deaminase activity 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0008179 adenylate cyclase binding 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0008504 monoamine transmembrane transporter activity 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0008603 cAMP-dependent protein kinase regulator activity 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0015132 prostaglandin transmembrane transporter activity 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0015368 calcium:monoatomic cation antiporter activity 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0017166 vinculin binding 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0035259 nuclear glucocorticoid receptor binding 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0036009 protein-glutamine N-methyltransferase activity 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0042301 phosphate ion binding 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0070008 serine-type exopeptidase activity 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0070679 inositol 1,4,5 trisphosphate binding 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0140900 chloride:bicarbonate antiporter activity 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:1990459 transferrin receptor binding 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:1990817 poly(A) RNA polymerase activity 1/3692 12/18639 0.0833333333333333 0.420706933911159 0.92933618383285 1 GO:0033293 monocarboxylic acid binding 11/3692 79/18639 0.139240506329114 0.702953357927507 0.932680920840784 1 GO:0004620 phospholipase activity 16/3692 109/18639 0.146788990825688 0.741061755146262 0.933391876242015 1 GO:0009378 four-way junction helicase activity 6/3692 48/18639 0.125 0.631060400866739 0.93416156648529 1 GO:0036121 double-stranded DNA helicase activity 6/3692 48/18639 0.125 0.631060400866739 0.93416156648529 1 GO:0043138 3'-5' DNA helicase activity 6/3692 48/18639 0.125 0.631060400866739 0.93416156648529 1 GO:0045499 chemorepellent activity 3/3692 28/18639 0.107142857142857 0.540908915028633 0.936055875181645 1 GO:0051119 sugar transmembrane transporter activity 3/3692 28/18639 0.107142857142857 0.540908915028633 0.936055875181645 1 GO:0051393 alpha-actinin binding 3/3692 28/18639 0.107142857142857 0.540908915028633 0.936055875181645 1 GO:0005085 guanyl-nucleotide exchange factor activity 37/3692 230/18639 0.160869565217391 0.81214729850676 0.937195765576369 1 GO:0046982 protein heterodimerization activity 62/3692 369/18639 0.168021680216802 0.848254630975345 0.939203265183846 1 GO:0008373 sialyltransferase activity 2/3692 21/18639 0.0952380952380952 0.480807924469896 0.940086182024394 1 GO:0009975 cyclase activity 2/3692 21/18639 0.0952380952380952 0.480807924469896 0.940086182024394 1 GO:0015174 basic amino acid transmembrane transporter activity 2/3692 21/18639 0.0952380952380952 0.480807924469896 0.940086182024394 1 GO:0036122 BMP binding 2/3692 21/18639 0.0952380952380952 0.480807924469896 0.940086182024394 1 GO:0030145 manganese ion binding 9/3692 68/18639 0.132352941176471 0.668181600917723 0.941251096744123 1 GO:0035325 Toll-like receptor binding 1/3692 13/18639 0.0769230769230769 0.388344862071839 0.943342240057101 1 GO:0043560 insulin receptor substrate binding 1/3692 13/18639 0.0769230769230769 0.388344862071839 0.943342240057101 1 GO:0046974 histone H3K9 methyltransferase activity 1/3692 13/18639 0.0769230769230769 0.388344862071839 0.943342240057101 1 GO:0051011 microtubule minus-end binding 1/3692 13/18639 0.0769230769230769 0.388344862071839 0.943342240057101 1 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/3692 13/18639 0.0769230769230769 0.388344862071839 0.943342240057101 1 GO:0071714 icosanoid transmembrane transporter activity 1/3692 13/18639 0.0769230769230769 0.388344862071839 0.943342240057101 1 GO:0097157 pre-mRNA intronic binding 1/3692 13/18639 0.0769230769230769 0.388344862071839 0.943342240057101 1 GO:0140852 histone ubiquitin ligase activity 1/3692 13/18639 0.0769230769230769 0.388344862071839 0.943342240057101 1 GO:0106222 lncRNA binding 3/3692 29/18639 0.103448275862069 0.522256883475922 0.945498428736738 1 GO:0005006 epidermal growth factor receptor activity 6/3692 50/18639 0.12 0.605817984832069 0.948910984645225 1 GO:1901682 sulfur compound transmembrane transporter activity 8/3692 63/18639 0.126984126984127 0.641077232626528 0.949280902259009 1 GO:0046972 histone H4K16 acetyltransferase activity 2/3692 22/18639 0.0909090909090909 0.458953018812174 0.950046422179742 1 GO:0020037 heme binding 21/3692 142/18639 0.147887323943662 0.746606671447973 0.950724742710113 1 GO:0023023 MHC protein complex binding 4/3692 37/18639 0.108108108108108 0.54578196831718 0.952531045461301 1 GO:0030551 cyclic nucleotide binding 4/3692 37/18639 0.108108108108108 0.54578196831718 0.952531045461301 1 GO:0042805 actinin binding 4/3692 37/18639 0.108108108108108 0.54578196831718 0.952531045461301 1 GO:0003689 DNA clamp loader activity 24/3692 160/18639 0.15 0.757272481040087 0.952609712849233 1 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 3/3692 30/18639 0.1 0.504848320693391 0.953630014515532 1 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/3692 30/18639 0.1 0.504848320693391 0.953630014515532 1 GO:0005344 oxygen carrier activity 1/3692 14/18639 0.0714285714285714 0.360605943352422 0.954572802158957 1 GO:0005545 1-phosphatidylinositol binding 1/3692 14/18639 0.0714285714285714 0.360605943352422 0.954572802158957 1 GO:0008559 ABC-type xenobiotic transporter activity 1/3692 14/18639 0.0714285714285714 0.360605943352422 0.954572802158957 1 GO:0015386 potassium:proton antiporter activity 1/3692 14/18639 0.0714285714285714 0.360605943352422 0.954572802158957 1 GO:0019992 diacylglycerol binding 1/3692 14/18639 0.0714285714285714 0.360605943352422 0.954572802158957 1 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/3692 14/18639 0.0714285714285714 0.360605943352422 0.954572802158957 1 GO:0042043 neurexin family protein binding 1/3692 14/18639 0.0714285714285714 0.360605943352422 0.954572802158957 1 GO:1901474 azole transmembrane transporter activity 1/3692 14/18639 0.0714285714285714 0.360605943352422 0.954572802158957 1 GO:0005030 neurotrophin receptor activity 6/3692 51/18639 0.117647058823529 0.593939200815754 0.955108337203818 1 GO:0035402 histone H3T11 kinase activity 39/3692 247/18639 0.157894736842105 0.797128927410618 0.956182840506058 1 GO:0003724 RNA helicase activity 10/3692 77/18639 0.12987012987013 0.655647169731677 0.956443100029125 1 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/3692 23/18639 0.0869565217391304 0.438998539733384 0.958412772201805 1 GO:0046915 transition metal ion transmembrane transporter activity 5/3692 45/18639 0.111111111111111 0.560942578548212 0.959369600115891 1 GO:0072349 modified amino acid transmembrane transporter activity 3/3692 31/18639 0.0967741935483871 0.488562890993604 0.960615301578221 1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 38/3692 243/18639 0.156378600823045 0.789474740178966 0.96066974939386 1 GO:0019199 transmembrane receptor protein kinase activity 10/3692 78/18639 0.128205128205128 0.647241436786399 0.96096691051328 1 GO:0017124 SH3 domain binding 16/3692 115/18639 0.139130434782609 0.702397663573414 0.961057767654571 1 GO:0035401 histone H3Y41 kinase activity 16/3692 115/18639 0.139130434782609 0.702397663573414 0.961057767654571 1 GO:0140801 histone H2AXY142 kinase activity 16/3692 115/18639 0.139130434782609 0.702397663573414 0.961057767654571 1 GO:0005253 monoatomic anion channel activity 14/3692 103/18639 0.135922330097087 0.686201600942473 0.961638719968039 1 GO:0005518 collagen binding 9/3692 72/18639 0.125 0.631060400866739 0.962503402130743 1 GO:0004559 alpha-mannosidase activity 1/3692 15/18639 0.0666666666666667 0.336565547128927 0.963577753269246 1 GO:0005041 low-density lipoprotein particle receptor activity 1/3692 15/18639 0.0666666666666667 0.336565547128927 0.963577753269246 1 GO:0047372 monoacylglycerol lipase activity 1/3692 15/18639 0.0666666666666667 0.336565547128927 0.963577753269246 1 GO:0008186 ATP-dependent activity, acting on RNA 10/3692 79/18639 0.126582278481013 0.639048507206824 0.965066329306395 1 GO:0060589 nucleoside-triphosphatase regulator activity 82/3692 490/18639 0.16734693877551 0.844848210139961 0.965132825710118 1 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/3692 24/18639 0.0833333333333333 0.420706933911159 0.96542568199073 1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/3692 24/18639 0.0833333333333333 0.420706933911159 0.96542568199073 1 GO:0004806 triacylglycerol lipase activity 2/3692 24/18639 0.0833333333333333 0.420706933911159 0.96542568199073 1 GO:0005540 hyaluronic acid binding 2/3692 24/18639 0.0833333333333333 0.420706933911159 0.96542568199073 1 GO:0015149 hexose transmembrane transporter activity 2/3692 24/18639 0.0833333333333333 0.420706933911159 0.96542568199073 1 GO:0015295 solute:proton symporter activity 2/3692 24/18639 0.0833333333333333 0.420706933911159 0.96542568199073 1 GO:0030215 semaphorin receptor binding 2/3692 24/18639 0.0833333333333333 0.420706933911159 0.96542568199073 1 GO:0055056 D-glucose transmembrane transporter activity 2/3692 24/18639 0.0833333333333333 0.420706933911159 0.96542568199073 1 GO:0140612 DNA damage sensor activity 2/3692 24/18639 0.0833333333333333 0.420706933911159 0.96542568199073 1 GO:0005003 ephrin receptor activity 6/3692 53/18639 0.113207547169811 0.571526400784971 0.965502671824908 1 GO:0005005 transmembrane-ephrin receptor activity 6/3692 53/18639 0.113207547169811 0.571526400784971 0.965502671824908 1 GO:0038064 collagen receptor activity 6/3692 53/18639 0.113207547169811 0.571526400784971 0.965502671824908 1 GO:0004676 3-phosphoinositide-dependent protein kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0004711 ribosomal protein S6 kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0035175 histone H3S10 kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0035979 histone H2AXS139 kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0044022 histone H3S28 kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0044023 histone H4S1 kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0044024 histone H2AS1 kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0044025 histone H2BS14 kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0072354 histone H3T3 kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0072371 histone H2AS121 kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0072518 Rho-dependent protein serine/threonine kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0140823 histone H2BS36 kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0140855 histone H3S57 kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0140995 histone H2A kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0140997 histone H4 kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0140998 histone H2B kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:1990244 histone H2AT120 kinase activity 38/3692 245/18639 0.155102040816327 0.783030048422403 0.965546693217684 1 GO:0042626 ATPase-coupled transmembrane transporter activity 13/3692 98/18639 0.13265306122449 0.669696751940213 0.96580637939304 1 GO:0042910 xenobiotic transmembrane transporter activity 3/3692 32/18639 0.09375 0.473295300650054 0.966602008127009 1 GO:0004714 transmembrane receptor protein tyrosine kinase activity 7/3692 60/18639 0.116666666666667 0.588989707475623 0.966854699867042 1 GO:0004677 DNA-dependent protein kinase activity 38/3692 246/18639 0.154471544715447 0.779846999445076 0.967782780707741 1 GO:0140857 histone H3T45 kinase activity 38/3692 246/18639 0.154471544715447 0.779846999445076 0.967782780707741 1 GO:0016500 protein-hormone receptor activity 8/3692 67/18639 0.119402985074627 0.602803965007034 0.968500228101123 1 GO:0071855 neuropeptide receptor binding 4/3692 40/18639 0.1 0.504848320693391 0.969789027234935 1 GO:0035403 histone H3T6 kinase activity 38/3692 247/18639 0.153846153846154 0.776689724143679 0.96989186074441 1 GO:0016798 hydrolase activity, acting on glycosyl bonds 18/3692 130/18639 0.138461538461538 0.699020751729311 0.970204161482473 1 GO:0015923 mannosidase activity 1/3692 16/18639 0.0625 0.315530200433369 0.970798056905948 1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/3692 16/18639 0.0625 0.315530200433369 0.970798056905948 1 GO:0016722 oxidoreductase activity, acting on metal ions 1/3692 16/18639 0.0625 0.315530200433369 0.970798056905948 1 GO:0030275 LRR domain binding 1/3692 16/18639 0.0625 0.315530200433369 0.970798056905948 1 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/3692 16/18639 0.0625 0.315530200433369 0.970798056905948 1 GO:0015662 P-type ion transporter activity 2/3692 25/18639 0.08 0.403878656554713 0.971292909884068 1 GO:0140358 P-type transmembrane transporter activity 2/3692 25/18639 0.08 0.403878656554713 0.971292909884068 1 GO:0008237 metallopeptidase activity 27/3692 184/18639 0.146739130434783 0.740810035800085 0.971365468858713 1 GO:0019956 chemokine binding 3/3692 33/18639 0.0909090909090909 0.458953018812174 0.971721783884224 1 GO:0004679 AMP-activated protein kinase activity 38/3692 248/18639 0.153225806451613 0.773557910739874 0.971879695654612 1 GO:0030695 GTPase regulator activity 81/3692 489/18639 0.165644171779141 0.83625181955347 0.972055946766013 1 GO:0004386 helicase activity 22/3692 155/18639 0.141935483870968 0.71655890679062 0.972671881456664 1 GO:0042562 hormone binding 12/3692 94/18639 0.127659574468085 0.644487217906457 0.972963636502338 1 GO:0140693 molecular condensate scaffold activity 5/3692 48/18639 0.104166666666667 0.525883667388949 0.973452631083763 1 GO:0001727 lipid kinase activity 4/3692 41/18639 0.0975609756097561 0.492534947017943 0.974094524597516 1 GO:0042169 SH2 domain binding 4/3692 41/18639 0.0975609756097561 0.492534947017943 0.974094524597516 1 GO:0008083 growth factor activity 23/3692 162/18639 0.141975308641975 0.716759961478271 0.974976736415734 1 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/3692 26/18639 0.0769230769230769 0.388344862071839 0.97619303596973 1 GO:0015145 monosaccharide transmembrane transporter activity 2/3692 26/18639 0.0769230769230769 0.388344862071839 0.97619303596973 1 GO:0052742 phosphatidylinositol kinase activity 2/3692 26/18639 0.0769230769230769 0.388344862071839 0.97619303596973 1 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/3692 17/18639 0.0588235294117647 0.296969600407877 0.976587326835779 1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/3692 17/18639 0.0588235294117647 0.296969600407877 0.976587326835779 1 GO:0019198 transmembrane receptor protein phosphatase activity 1/3692 17/18639 0.0588235294117647 0.296969600407877 0.976587326835779 1 GO:0030169 low-density lipoprotein particle binding 1/3692 17/18639 0.0588235294117647 0.296969600407877 0.976587326835779 1 GO:0038191 neuropilin binding 1/3692 17/18639 0.0588235294117647 0.296969600407877 0.976587326835779 1 GO:0170055 lipid transmembrane transporter activity 6/3692 56/18639 0.107142857142857 0.540908915028633 0.977017898179653 1 GO:0005004 GPI-linked ephrin receptor activity 5/3692 49/18639 0.102040816326531 0.515151347646317 0.977032039172083 1 GO:0005008 hepatocyte growth factor receptor activity 5/3692 49/18639 0.102040816326531 0.515151347646317 0.977032039172083 1 GO:0005009 insulin receptor activity 5/3692 49/18639 0.102040816326531 0.515151347646317 0.977032039172083 1 GO:0005011 macrophage colony-stimulating factor receptor activity 5/3692 49/18639 0.102040816326531 0.515151347646317 0.977032039172083 1 GO:0005018 platelet-derived growth factor alpha-receptor activity 5/3692 49/18639 0.102040816326531 0.515151347646317 0.977032039172083 1 GO:0005020 stem cell factor receptor activity 5/3692 49/18639 0.102040816326531 0.515151347646317 0.977032039172083 1 GO:0008288 boss receptor activity 5/3692 49/18639 0.102040816326531 0.515151347646317 0.977032039172083 1 GO:0016763 pentosyltransferase activity 5/3692 49/18639 0.102040816326531 0.515151347646317 0.977032039172083 1 GO:0036332 placental growth factor receptor activity 5/3692 49/18639 0.102040816326531 0.515151347646317 0.977032039172083 1 GO:0038062 protein tyrosine kinase collagen receptor activity 5/3692 49/18639 0.102040816326531 0.515151347646317 0.977032039172083 1 GO:0060175 brain-derived neurotrophic factor receptor activity 5/3692 49/18639 0.102040816326531 0.515151347646317 0.977032039172083 1 GO:0008028 monocarboxylic acid transmembrane transporter activity 8/3692 70/18639 0.114285714285714 0.576969509363875 0.978276596225263 1 GO:0004252 serine-type endopeptidase activity 25/3692 176/18639 0.142045454545455 0.717114091894022 0.978998445959564 1 GO:0004713 protein tyrosine kinase activity 19/3692 140/18639 0.135714285714286 0.685151292369602 0.979258663239928 1 GO:0005343 organic acid:sodium symporter activity 3/3692 35/18639 0.0857142857142857 0.432727132022907 0.979813342412999 1 GO:0005007 fibroblast growth factor receptor activity 5/3692 50/18639 0.1 0.504848320693391 0.980156600786178 1 GO:0005017 platelet-derived growth factor receptor activity 5/3692 50/18639 0.1 0.504848320693391 0.980156600786178 1 GO:0005019 platelet-derived growth factor beta-receptor activity 5/3692 50/18639 0.1 0.504848320693391 0.980156600786178 1 GO:0005104 fibroblast growth factor receptor binding 2/3692 27/18639 0.0740740740740741 0.373961719032142 0.980278866563368 1 GO:0008395 steroid hydroxylase activity 2/3692 27/18639 0.0740740740740741 0.373961719032142 0.980278866563368 1 GO:0015280 ligand-gated sodium channel activity 1/3692 18/18639 0.0555555555555556 0.280471289274106 0.981229126283868 1 GO:0022851 GABA-gated chloride ion channel activity 1/3692 18/18639 0.0555555555555556 0.280471289274106 0.981229126283868 1 GO:0030228 lipoprotein particle receptor activity 1/3692 18/18639 0.0555555555555556 0.280471289274106 0.981229126283868 1 GO:0032393 MHC class I receptor activity 1/3692 18/18639 0.0555555555555556 0.280471289274106 0.981229126283868 1 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/3692 18/18639 0.0555555555555556 0.280471289274106 0.981229126283868 1 GO:0008201 heparin binding 24/3692 172/18639 0.13953488372093 0.704439517246592 0.982262259001251 1 GO:0005010 insulin-like growth factor receptor activity 5/3692 51/18639 0.0980392156862745 0.494949334013129 0.982879238132087 1 GO:0005021 vascular endothelial growth factor receptor activity 5/3692 51/18639 0.0980392156862745 0.494949334013129 0.982879238132087 1 GO:0005272 sodium channel activity 5/3692 51/18639 0.0980392156862745 0.494949334013129 0.982879238132087 1 GO:0004190 aspartic-type endopeptidase activity 3/3692 36/18639 0.0833333333333333 0.420706933911159 0.982978201142725 1 GO:0016298 lipase activity 17/3692 130/18639 0.130769230769231 0.660186265522127 0.983377064823101 1 GO:0005242 inward rectifier potassium channel activity 2/3692 28/18639 0.0714285714285714 0.360605943352422 0.983680635131193 1 GO:0001223 transcription coactivator binding 4/3692 44/18639 0.0909090909090909 0.458953018812174 0.983805051137634 1 GO:0004175 endopeptidase activity 64/3692 405/18639 0.158024691358025 0.797785000601902 0.984416130019654 1 GO:0036002 pre-mRNA binding 6/3692 59/18639 0.101694915254237 0.513405071891584 0.984876169984494 1 GO:0004890 GABA-A receptor activity 1/3692 19/18639 0.0526315789473684 0.265709642470206 0.984950841860902 1 GO:0008381 mechanosensitive monoatomic ion channel activity 1/3692 19/18639 0.0526315789473684 0.265709642470206 0.984950841860902 1 GO:0022821 solute:potassium antiporter activity 1/3692 19/18639 0.0526315789473684 0.265709642470206 0.984950841860902 1 GO:0005201 extracellular matrix structural constituent 23/3692 168/18639 0.136904761904762 0.691161391425476 0.985173055160326 1 GO:0008094 ATP-dependent activity, acting on DNA 30/3692 210/18639 0.142857142857143 0.721211886704844 0.985226401089445 1 GO:0070001 aspartic-type peptidase activity 3/3692 37/18639 0.0810810810810811 0.409336476237885 0.985664714879321 1 GO:0004181 metallocarboxypeptidase activity 2/3692 29/18639 0.0689655172413793 0.348171255650615 0.986508946715968 1 GO:0004629 phospholipase C activity 2/3692 29/18639 0.0689655172413793 0.348171255650615 0.986508946715968 1 GO:0099604 ligand-gated calcium channel activity 2/3692 29/18639 0.0689655172413793 0.348171255650615 0.986508946715968 1 GO:0000510 H3-H4 histone complex chaperone activity 20/3692 151/18639 0.132450331125828 0.668673272441578 0.986891239886866 1 GO:0140584 chromatin extrusion motor activity 20/3692 151/18639 0.132450331125828 0.668673272441578 0.986891239886866 1 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 20/3692 151/18639 0.132450331125828 0.668673272441578 0.986891239886866 1 GO:0140849 ATP-dependent H2AZ histone chaperone activity 20/3692 151/18639 0.132450331125828 0.668673272441578 0.986891239886866 1 GO:0140713 histone chaperone activity 22/3692 164/18639 0.134146341463415 0.677235552149671 0.987745282816254 1 GO:0005326 neurotransmitter transmembrane transporter activity 1/3692 20/18639 0.05 0.252424160346696 0.987934810273875 1 GO:0030627 pre-mRNA 5'-splice site binding 1/3692 20/18639 0.05 0.252424160346696 0.987934810273875 1 GO:0140664 ATP-dependent DNA damage sensor activity 1/3692 20/18639 0.05 0.252424160346696 0.987934810273875 1 GO:0042887 amide transmembrane transporter activity 3/3692 38/18639 0.0789473684210526 0.398564463705309 0.987941531866885 1 GO:0042826 histone deacetylase binding 16/3692 127/18639 0.125984251968504 0.636029380401123 0.988067473346512 1 GO:0015616 DNA translocase activity 20/3692 152/18639 0.131578947368421 0.664274106175515 0.988088379393345 1 GO:0140674 ATP-dependent histone chaperone activity 20/3692 152/18639 0.131578947368421 0.664274106175515 0.988088379393345 1 GO:0004180 carboxypeptidase activity 4/3692 46/18639 0.0869565217391304 0.438998539733384 0.988236611189836 1 GO:0042277 peptide binding 36/3692 249/18639 0.144578313253012 0.729901186544662 0.988824422329763 1 GO:0001965 G-protein alpha-subunit binding 2/3692 30/18639 0.0666666666666667 0.336565547128927 0.988857441873142 1 GO:0061775 cohesin loader activity 20/3692 153/18639 0.130718954248366 0.659932445350838 0.989184786708973 1 GO:0005254 chloride channel activity 9/3692 83/18639 0.108433734939759 0.547425889908496 0.990185996420698 1 GO:0140457 protein demethylase activity 2/3692 31/18639 0.0645161290322581 0.325708593995736 0.990805175686584 1 GO:0017171 serine hydrolase activity 27/3692 198/18639 0.136363636363636 0.688429528218261 0.991100437493357 1 GO:0016782 transferase activity, transferring sulphur-containing groups 7/3692 70/18639 0.1 0.504848320693391 0.991276337970951 1 GO:0004177 aminopeptidase activity 3/3692 40/18639 0.075 0.378636240520043 0.991496250180624 1 GO:0015144 carbohydrate transmembrane transporter activity 3/3692 40/18639 0.075 0.378636240520043 0.991496250180624 1 GO:0004674 protein serine/threonine kinase activity 67/3692 433/18639 0.15473441108545 0.781174075899705 0.992043291683094 1 GO:0015377 chloride:monoatomic cation symporter activity 1/3692 22/18639 0.0454545454545455 0.229476509406087 0.992245375948568 1 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/3692 22/18639 0.0454545454545455 0.229476509406087 0.992245375948568 1 GO:0033038 bitter taste receptor activity 1/3692 22/18639 0.0454545454545455 0.229476509406087 0.992245375948568 1 GO:0033691 sialic acid binding 1/3692 22/18639 0.0454545454545455 0.229476509406087 0.992245375948568 1 GO:0071813 lipoprotein particle binding 2/3692 32/18639 0.0625 0.315530200433369 0.992418720190556 1 GO:0071814 protein-lipid complex binding 2/3692 32/18639 0.0625 0.315530200433369 0.992418720190556 1 GO:0008236 serine-type peptidase activity 26/3692 194/18639 0.134020618556701 0.6766008421664 0.992619622965968 1 GO:0141003 histone H2AX kinase activity 53/3692 354/18639 0.149717514124294 0.755846355840388 0.99269435906496 1 GO:0001530 lipopolysaccharide binding 3/3692 41/18639 0.0731707317073171 0.369401210263457 0.992870070621395 1 GO:0140828 metal cation:monoatomic cation antiporter activity 3/3692 41/18639 0.0731707317073171 0.369401210263457 0.992870070621395 1 GO:0106310 protein serine kinase activity 54/3692 361/18639 0.149584487534626 0.755174773336375 0.993283772480938 1 GO:0140658 ATP-dependent chromatin remodeler activity 20/3692 158/18639 0.126582278481013 0.639048507206824 0.993403536685897 1 GO:0042379 chemokine receptor binding 7/3692 72/18639 0.0972222222222222 0.490824756229686 0.993413845391785 1 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/3692 23/18639 0.0434782608695652 0.219499269866692 0.993783221573421 1 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/3692 23/18639 0.0434782608695652 0.219499269866692 0.993783221573421 1 GO:0016849 phosphorus-oxygen lyase activity 1/3692 23/18639 0.0434782608695652 0.219499269866692 0.993783221573421 1 GO:0016917 GABA receptor activity 1/3692 23/18639 0.0434782608695652 0.219499269866692 0.993783221573421 1 GO:0031681 G-protein beta-subunit binding 1/3692 23/18639 0.0434782608695652 0.219499269866692 0.993783221573421 1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/3692 23/18639 0.0434782608695652 0.219499269866692 0.993783221573421 1 GO:0048020 CCR chemokine receptor binding 4/3692 50/18639 0.08 0.403878656554713 0.993879785608059 1 GO:0140996 histone H3 kinase activity 53/3692 357/18639 0.148459383753501 0.749494705791309 0.994077226328131 1 GO:0061980 regulatory RNA binding 5/3692 58/18639 0.0862068965517241 0.435214069563268 0.99411170431121 1 GO:0008514 organic anion transmembrane transporter activity 38/3692 269/18639 0.141263940520446 0.713168631462783 0.994128914478089 1 GO:0015020 glucuronosyltransferase activity 2/3692 34/18639 0.0588235294117647 0.296969600407877 0.994857926614764 1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/3692 34/18639 0.0588235294117647 0.296969600407877 0.994857926614764 1 GO:0019825 oxygen binding 2/3692 34/18639 0.0588235294117647 0.296969600407877 0.994857926614764 1 GO:0090482 vitamin transmembrane transporter activity 2/3692 34/18639 0.0588235294117647 0.296969600407877 0.994857926614764 1 GO:0005245 voltage-gated calcium channel activity 3/3692 43/18639 0.0697674418604651 0.352219758623296 0.995002399809343 1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/3692 24/18639 0.0416666666666667 0.21035346695558 0.995016158077016 1 GO:0008238 exopeptidase activity 11/3692 102/18639 0.107843137254902 0.544444267414441 0.995043132061577 1 GO:0015171 amino acid transmembrane transporter activity 11/3692 102/18639 0.107843137254902 0.544444267414441 0.995043132061577 1 GO:0035173 histone kinase activity 53/3692 360/18639 0.147222222222222 0.743248916576381 0.995216779851652 1 GO:0008509 monoatomic anion transmembrane transporter activity 18/3692 149/18639 0.120805369127517 0.609883877347721 0.995516557481952 1 GO:1990841 promoter-specific chromatin binding 6/3692 68/18639 0.0882352941176471 0.445454400611816 0.995956110061411 1 GO:0004709 MAP kinase kinase kinase activity 1/3692 25/18639 0.04 0.201939328277356 0.996004626751723 1 GO:0005251 delayed rectifier potassium channel activity 1/3692 25/18639 0.04 0.201939328277356 0.996004626751723 1 GO:0005537 D-mannose binding 1/3692 25/18639 0.04 0.201939328277356 0.996004626751723 1 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/3692 25/18639 0.04 0.201939328277356 0.996004626751723 1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/3692 25/18639 0.04 0.201939328277356 0.996004626751723 1 GO:0019955 cytokine binding 17/3692 144/18639 0.118055555555556 0.596001489707476 0.996176399030156 1 GO:0005262 calcium channel activity 15/3692 131/18639 0.114503816793893 0.578070596213807 0.996214106724528 1 GO:0015026 coreceptor activity 5/3692 61/18639 0.0819672131147541 0.413810098929009 0.996333623202356 1 GO:0004435 phosphatidylinositol phospholipase C activity 1/3692 26/18639 0.0384615384615385 0.19417243103592 0.996797090383002 1 GO:0019865 immunoglobulin binding 1/3692 26/18639 0.0384615384615385 0.19417243103592 0.996797090383002 1 GO:0005096 GTPase activator activity 37/3692 271/18639 0.136531365313653 0.689276305005737 0.996973199203846 1 GO:0004497 monooxygenase activity 11/3692 106/18639 0.10377358490566 0.523899200719557 0.99701932836894 1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 3/3692 46/18639 0.0652173913043478 0.329248904800038 0.997086966552722 1 GO:0005044 scavenger receptor activity 1/3692 27/18639 0.037037037037037 0.186980859516071 0.997432406683757 1 GO:0140299 molecular sensor activity 6/3692 71/18639 0.0845070422535211 0.426632383684556 0.997442502005838 1 GO:0015108 chloride transmembrane transporter activity 13/3692 121/18639 0.107438016528926 0.542399022232569 0.997470310266771 1 GO:0099095 ligand-gated monoatomic anion channel activity 3/3692 47/18639 0.0638297872340425 0.322243608953228 0.997570673872908 1 GO:0008527 taste receptor activity 1/3692 28/18639 0.0357142857142857 0.180302971676211 0.997941731556075 1 GO:0141052 histone H3 demethylase activity 1/3692 28/18639 0.0357142857142857 0.180302971676211 0.997941731556075 1 GO:0038024 cargo receptor activity 5/3692 65/18639 0.0769230769230769 0.388344862071839 0.99807621204195 1 GO:0004896 cytokine receptor activity 9/3692 96/18639 0.09375 0.473295300650054 0.998291167968571 1 GO:0008235 metalloexopeptidase activity 5/3692 66/18639 0.0757575757575758 0.382460849010145 0.998366242816207 1 GO:0015103 inorganic anion transmembrane transporter activity 19/3692 165/18639 0.115151515151515 0.58134049049542 0.998420542339032 1 GO:0005539 glycosaminoglycan binding 31/3692 242/18639 0.128099173553719 0.646706526508063 0.998501359840477 1 GO:0030246 carbohydrate binding 37/3692 280/18639 0.132142857142857 0.667120995201981 0.998623176630455 1 GO:0032452 histone demethylase activity 1/3692 30/18639 0.0333333333333333 0.168282773564464 0.998677376453027 1 GO:0015085 calcium ion transmembrane transporter activity 16/3692 147/18639 0.108843537414966 0.549494770822739 0.998736611291059 1 GO:0046943 carboxylic acid transmembrane transporter activity 22/3692 188/18639 0.117021276595745 0.590779949747585 0.998916126205327 1 GO:0035198 miRNA binding 2/3692 42/18639 0.0476190476190476 0.240403962234948 0.99893936135026 1 GO:0005184 neuropeptide hormone activity 1/3692 31/18639 0.032258064516129 0.162854296997868 0.998939783145242 1 GO:0005342 organic acid transmembrane transporter activity 22/3692 189/18639 0.116402116402116 0.587654129907651 0.999028195783641 1 GO:0160041 neuropeptide activity 1/3692 32/18639 0.03125 0.157765100216685 0.999150140014748 1 GO:0017046 peptide hormone binding 3/3692 53/18639 0.0566037735849057 0.285763200392486 0.999195275023919 1 GO:0008081 phosphoric diester hydrolase activity 7/3692 87/18639 0.0804597701149425 0.40619979825905 0.999290646585991 1 GO:0042923 neuropeptide binding 1/3692 33/18639 0.0303030303030303 0.152984339604058 0.999318769190088 1 GO:0008009 chemokine activity 2/3692 45/18639 0.0444444444444444 0.224377031419285 0.999418279672702 1 GO:0001664 G protein-coupled receptor binding 38/3692 297/18639 0.127946127946128 0.645933878328245 0.999490155338929 1 GO:0140359 ABC-type transporter activity 2/3692 47/18639 0.0425531914893617 0.214829072635486 0.999611073987682 1 GO:0099094 ligand-gated monoatomic cation channel activity 13/3692 136/18639 0.0955882352941176 0.4825756006628 0.999634359420395 1 GO:0008188 neuropeptide receptor activity 2/3692 48/18639 0.0416666666666667 0.21035346695558 0.999682179939073 1 GO:0015291 secondary active transmembrane transporter activity 35/3692 287/18639 0.121951219512195 0.615668683772428 0.999784561162208 1 GO:0008227 G protein-coupled amine receptor activity 1/3692 41/18639 0.024390243902439 0.123133736754486 0.999883945651539 1 GO:0005126 cytokine receptor binding 32/3692 275/18639 0.116363636363636 0.587459864079582 0.999898610076478 1 GO:0005267 potassium channel activity 10/3692 124/18639 0.0806451612903226 0.40713574249467 0.999913905558488 1 GO:0005261 monoatomic cation channel activity 41/3692 341/18639 0.120234604105572 0.607002379719327 0.999956074950183 1 GO:0015294 solute:monoatomic cation symporter activity 8/3692 116/18639 0.0689655172413793 0.348171255650615 0.999974858774517 1 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 29/3692 268/18639 0.108208955223881 0.546291093287625 0.999975548633852 1 GO:0015079 potassium ion transmembrane transporter activity 13/3692 160/18639 0.08125 0.41018926056338 0.999987600868659 1 GO:0015293 symporter activity 11/3692 146/18639 0.0753424657534247 0.380365173125158 0.999990104657626 1 GO:0008146 sulfotransferase activity 1/3692 53/18639 0.0188679245283019 0.0952544001308285 0.99999185261972 1 GO:0001217 DNA-binding transcription repressor activity 29/3692 278/18639 0.10431654676259 0.526640334536271 0.999992457309978 1 GO:0005249 voltage-gated potassium channel activity 5/3692 98/18639 0.0510204081632653 0.257575673823159 0.999993791501252 1 GO:0005244 voltage-gated monoatomic ion channel activity 14/3692 173/18639 0.0809248554913295 0.40854777397153 0.999994374772218 1 GO:0015370 solute:sodium symporter activity 3/3692 79/18639 0.0379746835443038 0.191714552162047 0.999994606621352 1 GO:0022832 voltage-gated channel activity 14/3692 175/18639 0.08 0.403878656554713 0.999995811386286 1 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 4/3692 91/18639 0.043956043956044 0.221911349755337 0.999996176349033 1 GO:0005216 monoatomic ion channel activity 53/3692 448/18639 0.118303571428571 0.597253593677449 0.999997968960295 1 GO:0022834 ligand-gated channel activity 15/3692 188/18639 0.0797872340425532 0.402804511191535 0.999998095646834 1 GO:0022843 voltage-gated monoatomic cation channel activity 9/3692 143/18639 0.0629370629370629 0.317736705331505 0.999998837068997 1 GO:0022824 transmitter-gated monoatomic ion channel activity 1/3692 63/18639 0.0158730158730159 0.080134654078316 0.999999110775536 1 GO:0022835 transmitter-gated channel activity 1/3692 63/18639 0.0158730158730159 0.080134654078316 0.999999110775536 1 GO:0015276 ligand-gated monoatomic ion channel activity 14/3692 186/18639 0.0752688172043011 0.379993359661692 0.999999197069638 1 GO:0015081 sodium ion transmembrane transporter activity 11/3692 164/18639 0.0670731707317073 0.338617776074836 0.999999423909219 1 GO:0140375 immune receptor activity 10/3692 156/18639 0.0641025641025641 0.323620718393199 0.999999453751579 1 GO:0005179 hormone activity 7/3692 132/18639 0.053030303030303 0.267722594307101 0.999999623232871 1 GO:0005125 cytokine activity 19/3692 234/18639 0.0811965811965812 0.409919576631386 0.999999802649192 1 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/3692 73/18639 0.0136986301369863 0.0691573042045741 0.999999903077429 1 GO:0030594 neurotransmitter receptor activity 2/3692 97/18639 0.0206185567010309 0.104092437256369 0.999999988148557 1 GO:0003730 mRNA 3'-UTR binding 20/3692 262/18639 0.0763358778625954 0.385380397475871 0.999999990116118 1 GO:0008528 G protein-coupled peptide receptor activity 4/3692 122/18639 0.0327868852459016 0.165524039571604 0.99999999079385 1 GO:0001653 peptide receptor activity 4/3692 128/18639 0.03125 0.157765100216685 0.999999997207666 1 GO:0022836 gated channel activity 25/3692 318/18639 0.0786163522012579 0.396893333878452 0.999999999253552 1 GO:0046873 metal ion transmembrane transporter activity 42/3692 450/18639 0.0933333333333333 0.471191765980498 0.999999999720488 1 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 45/3692 484/18639 0.0929752066115702 0.469383769239723 0.999999999946502 1 GO:0001216 DNA-binding transcription activator activity 45/3692 491/18639 0.0916496945010183 0.462691943609014 0.99999999997866 1 GO:0003823 antigen binding 4/3692 174/18639 0.0229885057471264 0.116057085216872 0.999999999999754 1 GO:0045182 translation regulator activity 18/3692 356/18639 0.050561797752809 0.255260386867445 1 1 GO:0004984 olfactory receptor activity 1/3692 419/18639 0.00238663484486874 0.0120488859354031 1 1 GO:0030371 translation repressor activity 8/3692 329/18639 0.0243161094224924 0.12275947007742 1 1