ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 67/844 175/18639 0.382857142857143 8.45506431956669 1.64872299923401e-44 1.51847388229453e-41 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 17/844 68/18639 0.25 5.5210308056872 6.15720913887687e-09 2.8353948084528e-06 GO:0004866 endopeptidase inhibitor activity 26/844 161/18639 0.161490683229814 3.5663801477731 1.60473996713108e-08 4.92655169909241e-06 GO:0004857 enzyme inhibitor activity 46/844 416/18639 0.110576923076923 2.44199439482319 2.18254777075651e-08 5.02531624216687e-06 GO:0030414 peptidase inhibitor activity 26/844 169/18639 0.153846153846154 3.39755741888443 4.46303801818928e-08 8.22091602950465e-06 GO:0009055 electron transfer activity 20/844 116/18639 0.172413793103448 3.80760745219807 2.41258927220109e-07 3.34144328289406e-05 GO:0061135 endopeptidase regulator activity 26/844 184/18639 0.141304347826087 3.12058262930146 2.53964201740048e-07 3.34144328289406e-05 GO:0022853 active monoatomic ion transmembrane transporter activity 20/844 118/18639 0.169491525423729 3.74307173266929 3.21670397792925e-07 3.70323045459105e-05 GO:0098641 cadherin binding involved in cell-cell adhesion 8/844 18/18639 0.444444444444444 9.81516587677725 4.99157364626105e-07 5.10804369800714e-05 GO:0061134 peptidase regulator activity 28/844 226/18639 0.123893805309735 2.73608606299543 1.36937289586913e-06 0.000126119243709547 GO:0005201 extracellular matrix structural constituent 23/844 168/18639 0.136904761904762 3.02342163168585 2.15621991419984e-06 0.000180534412816187 GO:0048306 calcium-dependent protein binding 15/844 80/18639 0.1875 4.1407731042654 2.57618696591131e-06 0.000197722349633693 GO:0045296 cadherin binding 35/844 334/18639 0.104790419161677 2.31420452932997 3.63357670153652e-06 0.000257424934008856 GO:0070492 oligosaccharide binding 7/844 17/18639 0.411764705882353 9.0934625034848 4.96941740244753e-06 0.00032691667340387 GO:0008137 NADH dehydrogenase (ubiquinone) activity 10/844 41/18639 0.24390243902439 5.38637151774361 1.07163565397789e-05 0.000640007278576569 GO:0015078 proton transmembrane transporter activity 23/844 185/18639 0.124324324324324 2.74559369796337 1.11184760664768e-05 0.000640007278576569 GO:0015399 primary active transmembrane transporter activity 21/844 166/18639 0.126506024096386 2.79377462456461 2.03108112295833e-05 0.00107282490481508 GO:0003954 NADH dehydrogenase activity 10/844 44/18639 0.227272727272727 5.01911891426109 2.09672619833565e-05 0.00107282490481508 GO:0004129 cytochrome-c oxidase activity 6/844 15/18639 0.4 8.83364928909953 2.98115790803467e-05 0.00139184804548127 GO:0019843 rRNA binding 12/844 65/18639 0.184615384615385 4.07706890266132 3.02247132569223e-05 0.00139184804548127 GO:0001968 fibronectin binding 8/844 30/18639 0.266666666666667 5.88909952606635 4.11247619082563e-05 0.00173374494163856 GO:0050840 extracellular matrix binding 12/844 67/18639 0.17910447761194 3.95536535332815 4.14141028404434e-05 0.00173374494163856 GO:0016675 oxidoreductase activity, acting on a heme group of donors 6/844 16/18639 0.375 8.28154620853081 4.58732694991887e-05 0.00183692526994577 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 11/844 58/18639 0.189655172413793 4.18836819741788 4.97235015932418e-05 0.00190813937364066 GO:1990948 ubiquitin ligase inhibitor activity 5/844 11/18639 0.454545454545455 10.0382378285222 6.91737209887594e-05 0.0025483598812259 GO:0019956 chemokine binding 8/844 33/18639 0.242424242424242 5.3537268418785 8.64681959462042e-05 0.00306296955640208 GO:0004867 serine-type endopeptidase inhibitor activity 14/844 95/18639 0.147368421052632 3.25450236966825 9.21477684767802e-05 0.00314326276915239 GO:0016209 antioxidant activity 13/844 86/18639 0.151162790697674 3.33829769646203 0.0001249483347053 0.00405844614196082 GO:0005178 integrin binding 19/844 161/18639 0.118012422360248 2.6062008772188 0.000127790377977051 0.00405844614196082 GO:0005520 insulin-like growth factor binding 6/844 19/18639 0.315789473684211 6.9739336492891 0.000138283582712176 0.00424530598926381 GO:0098631 cell adhesion mediator activity 12/844 76/18639 0.157894736842105 3.48696682464455 0.000147511147195048 0.00438250859892386 GO:0004869 cysteine-type endopeptidase inhibitor activity 8/844 36/18639 0.222222222222222 4.90758293838863 0.000167073942170904 0.00480859689810633 GO:0043236 laminin binding 7/844 29/18639 0.241379310344828 5.3306504330773 0.000247683917662826 0.0069126329747716 GO:0019207 kinase regulator activity 27/844 287/18639 0.0940766550522648 2.07760044255825 0.000278844783368908 0.00755341310243425 GO:0031386 protein tag activity 5/844 15/18639 0.333333333333333 7.36137440758294 0.000386346647448061 0.009616898981072 GO:0055105 ubiquitin-protein transferase inhibitor activity 5/844 15/18639 0.333333333333333 7.36137440758294 0.000386346647448061 0.009616898981072 GO:0141047 molecular tag activity 5/844 15/18639 0.333333333333333 7.36137440758294 0.000386346647448061 0.009616898981072 GO:0048027 mRNA 5'-UTR binding 6/844 24/18639 0.25 5.5210308056872 0.000564997753104442 0.0136937613318208 GO:0016651 oxidoreductase activity, acting on NAD(P)H 12/844 88/18639 0.136363636363636 3.01147134855666 0.000594783567741191 0.0140460427151189 GO:0031625 ubiquitin protein ligase binding 27/844 302/18639 0.0894039735099338 1.97440836759675 0.000619653841661164 0.0142675297042483 GO:0098632 cell-cell adhesion mediator activity 9/844 55/18639 0.163636363636364 3.61376561826799 0.000748586587968206 0.0168158109150907 GO:0043548 phosphatidylinositol 3-kinase binding 6/844 26/18639 0.230769230769231 5.09633612832665 0.000894490912785338 0.0196149078732213 GO:0003779 actin binding 35/844 443/18639 0.0790067720090293 1.74479528847903 0.00103690889343392 0.0222091416477358 GO:0050786 RAGE receptor binding 4/844 11/18639 0.363636363636364 8.03059026281775 0.00106687030360147 0.0223315352185671 GO:0051087 protein-folding chaperone binding 15/844 134/18639 0.111940298507463 2.47210334583009 0.0011009983020873 0.0225337652493867 GO:0019838 growth factor binding 15/844 136/18639 0.110294117647059 2.435748884862 0.00128083554074461 0.025644555065778 GO:0045295 gamma-catenin binding 4/844 12/18639 0.333333333333333 7.36137440758294 0.00154322382549096 0.0302406200697271 GO:0044389 ubiquitin-like protein ligase binding 27/844 322/18639 0.0838509316770186 1.85177430749757 0.00160852959977584 0.0308636616956989 GO:0005507 copper ion binding 9/844 63/18639 0.142857142857143 3.15487474610697 0.00201955003515731 0.0379592975995894 GO:0031994 insulin-like growth factor I binding 4/844 13/18639 0.307692307692308 6.79511483776887 0.00214971977895266 0.039597838328308 GO:0032036 myosin heavy chain binding 4/844 14/18639 0.285714285714286 6.30974949221395 0.00290260704067019 0.050439643102967 GO:0042043 neurexin family protein binding 4/844 14/18639 0.285714285714286 6.30974949221395 0.00290260704067019 0.050439643102967 GO:0044548 S100 protein binding 4/844 14/18639 0.285714285714286 6.30974949221395 0.00290260704067019 0.050439643102967 GO:0140313 molecular sequestering activity 8/844 55/18639 0.145454545454545 3.2122361051271 0.00315169361839563 0.0537538856026366 GO:0002020 protease binding 14/844 136/18639 0.102941176470588 2.2733656258712 0.00348318727257819 0.0583275541462639 GO:0019957 C-C chemokine binding 5/844 24/18639 0.208333333333333 4.60085900473934 0.00389746022893093 0.0640993012650962 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 8/844 59/18639 0.135593220338983 2.99445738613543 0.00489982495510308 0.0791708558535076 GO:0055106 ubiquitin-protein transferase regulator activity 6/844 36/18639 0.166666666666667 3.68068720379147 0.0051514798492163 0.0818019472608312 GO:0005080 protein kinase C binding 7/844 52/18639 0.134615384615385 2.97286274152388 0.00862312637422262 0.134165611276487 GO:0031720 haptoglobin binding 3/844 10/18639 0.3 6.62523696682464 0.0087404307020513 0.134165611276487 GO:0008201 heparin binding 15/844 172/18639 0.0872093023255814 1.92594097872809 0.011599039343948 0.172583751600062 GO:0042608 T cell receptor binding 3/844 11/18639 0.272727272727273 6.02294269711331 0.01161801585147 0.172583751600062 GO:0019887 protein kinase regulator activity 20/844 255/18639 0.0784313725490196 1.73208809590187 0.0122960902894881 0.179757129470136 GO:0005200 structural constituent of cytoskeleton 11/844 112/18639 0.0982142857142857 2.16897638794854 0.0126421577561617 0.181928551459764 GO:0019955 cytokine binding 13/844 144/18639 0.0902777777777778 1.99370556872038 0.0138267142980973 0.192916857409326 GO:0004601 peroxidase activity 7/844 57/18639 0.12280701754386 2.71208530805687 0.0140421796680463 0.192916857409326 GO:0051015 actin filament binding 17/844 209/18639 0.0813397129186603 1.79631624299871 0.0144132703924539 0.192916857409326 GO:0004126 cytidine deaminase activity 3/844 12/18639 0.25 5.5210308056872 0.0149762798601297 0.192916857409326 GO:0015269 calcium-activated potassium channel activity 3/844 12/18639 0.25 5.5210308056872 0.0149762798601297 0.192916857409326 GO:0035014 phosphatidylinositol 3-kinase regulator activity 3/844 12/18639 0.25 5.5210308056872 0.0149762798601297 0.192916857409326 GO:0097371 MDM2/MDM4 family protein binding 3/844 12/18639 0.25 5.5210308056872 0.0149762798601297 0.192916857409326 GO:0001221 transcription coregulator binding 11/844 115/18639 0.0956521739130435 2.11239439521945 0.0151896703563355 0.192916857409326 GO:0008009 chemokine activity 6/844 45/18639 0.133333333333333 2.94454976303318 0.0152909126936816 0.192916857409326 GO:0042379 chemokine receptor binding 8/844 72/18639 0.111111111111111 2.45379146919431 0.0158636951453091 0.195418133334291 GO:0033691 sialic acid binding 4/844 22/18639 0.181818181818182 4.01529513140888 0.0159135287731507 0.195418133334291 GO:0001664 G protein-coupled receptor binding 22/844 297/18639 0.0740740740740741 1.63586097946288 0.0165164313660381 0.200153069580541 GO:0019825 oxygen binding 5/844 34/18639 0.147058823529412 3.247665179816 0.0175945436758997 0.210449022409138 GO:0016493 C-C chemokine receptor activity 4/844 23/18639 0.173913043478261 3.84071708221718 0.0185893880489437 0.21403867039023 GO:0005504 fatty acid binding 6/844 47/18639 0.127659574468085 2.81924977311687 0.0186881851795877 0.21403867039023 GO:0039706 co-receptor binding 3/844 13/18639 0.230769230769231 5.09633612832665 0.0188242478844828 0.21403867039023 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 3/844 13/18639 0.230769230769231 5.09633612832665 0.0188242478844828 0.21403867039023 GO:0005125 cytokine activity 18/844 234/18639 0.0769230769230769 1.69877870944222 0.0202052392253219 0.226939333250262 GO:0019210 kinase inhibitor activity 9/844 90/18639 0.1 2.20841232227488 0.0205699703921489 0.228252322062279 GO:0017022 myosin binding 8/844 76/18639 0.105263157894737 2.32464454976303 0.0213768092659962 0.234381444452173 GO:0005344 oxygen carrier activity 3/844 14/18639 0.214285714285714 4.73231211916046 0.0231665135691589 0.248097197641807 GO:0008191 metalloendopeptidase inhibitor activity 3/844 14/18639 0.214285714285714 4.73231211916046 0.0231665135691589 0.248097197641807 GO:0043394 proteoglycan binding 5/844 37/18639 0.135135135135135 2.98434097604714 0.0246788468323918 0.258867899558821 GO:0019211 phosphatase activator activity 4/844 25/18639 0.16 3.53345971563981 0.0247343921402565 0.258867899558821 GO:1901681 sulfur compound binding 20/844 275/18639 0.0727272727272727 1.60611805256355 0.0255898153602055 0.264811460075835 GO:0005539 glycosaminoglycan binding 18/844 242/18639 0.0743801652892562 1.64262073557636 0.027182043599708 0.278162912837012 GO:0001637 G protein-coupled chemoattractant receptor activity 4/844 26/18639 0.153846153846154 3.39755741888443 0.0282138380671012 0.279408009245164 GO:0004950 chemokine receptor activity 4/844 26/18639 0.153846153846154 3.39755741888443 0.0282138380671012 0.279408009245164 GO:0005227 calcium-activated cation channel activity 4/844 26/18639 0.153846153846154 3.39755741888443 0.0282138380671012 0.279408009245164 GO:0004896 cytokine receptor activity 9/844 96/18639 0.09375 2.0703865521327 0.0298175600172336 0.292148646551831 GO:0030246 carbohydrate binding 20/844 280/18639 0.0714285714285714 1.57743737305349 0.0301940526098723 0.292723394249393 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 3/844 16/18639 0.1875 4.1407731042654 0.0333331147766752 0.316866059757437 GO:0015036 disulfide oxidoreductase activity 5/844 40/18639 0.125 2.7605154028436 0.0333724297464401 0.316866059757437 GO:0004860 protein kinase inhibitor activity 8/844 84/18639 0.0952380952380952 2.10324983073798 0.0362167571015713 0.340363605005584 GO:0019209 kinase activator activity 12/844 148/18639 0.0810810810810811 1.79060458562828 0.036688680112889 0.341315902868391 GO:0008429 phosphatidylethanolamine binding 3/844 17/18639 0.176470588235294 3.8971982157792 0.0391487777740915 0.350058488640177 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 3/844 17/18639 0.176470588235294 3.8971982157792 0.0391487777740915 0.350058488640177 GO:0036041 long-chain fatty acid binding 3/844 17/18639 0.176470588235294 3.8971982157792 0.0391487777740915 0.350058488640177 GO:0051787 misfolded protein binding 3/844 17/18639 0.176470588235294 3.8971982157792 0.0391487777740915 0.350058488640177 GO:0035198 miRNA binding 5/844 42/18639 0.119047619047619 2.62906228842248 0.040103153001989 0.355144268411844 GO:0005518 collagen binding 7/844 72/18639 0.0972222222222222 2.14706753554502 0.0440181639089174 0.380475133289915 GO:0044325 transmembrane transporter binding 11/844 136/18639 0.0808823529411765 1.7862158488988 0.0448620621281445 0.380475133289915 GO:0022839 monoatomic ion-gated channel activity 4/844 30/18639 0.133333333333333 2.94454976303318 0.0449143076400035 0.380475133289915 GO:0031406 carboxylic acid binding 14/844 187/18639 0.0748663101604278 1.65335681881542 0.0452636804732203 0.380475133289915 GO:0003746 translation elongation factor activity 3/844 18/18639 0.166666666666667 3.68068720379147 0.0454421983299573 0.380475133289915 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 3/844 18/18639 0.166666666666667 3.68068720379147 0.0454421983299573 0.380475133289915 GO:0030547 signaling receptor inhibitor activity 5/844 44/18639 0.113636363636364 2.50955945713055 0.047600253282372 0.394670547184833 GO:0051082 unfolded protein binding 10/844 121/18639 0.0826446280991736 1.8251341506404 0.0479946810908808 0.394670547184833 GO:0043177 organic acid binding 14/844 189/18639 0.0740740740740741 1.63586097946288 0.0487112262174808 0.397018047312388 GO:0001786 phosphatidylserine binding 6/844 59/18639 0.101694915254237 2.24584303960157 0.049977532779136 0.398499235212187 GO:0004879 nuclear receptor activity 6/844 59/18639 0.101694915254237 2.24584303960157 0.049977532779136 0.398499235212187 GO:0051020 GTPase binding 21/844 315/18639 0.0666666666666667 1.47227488151659 0.0501910003090268 0.398499235212187 GO:0030295 protein kinase activator activity 11/844 139/18639 0.079136690647482 1.74766442769955 0.0510919568139234 0.402185403637807 GO:0098531 ligand-modulated transcription factor activity 6/844 60/18639 0.1 2.20841232227488 0.053500471311995 0.417575712528368 GO:0043425 bHLH transcription factor binding 4/844 32/18639 0.125 2.7605154028436 0.0549440105175056 0.421695280721855 GO:0120015 sterol transfer activity 4/844 32/18639 0.125 2.7605154028436 0.0549440105175056 0.421695280721855 GO:0030291 protein serine/threonine kinase inhibitor activity 5/844 46/18639 0.108695652173913 2.40044817638574 0.0558715928490298 0.425270553834351 GO:0043021 ribonucleoprotein complex binding 13/844 177/18639 0.0734463276836158 1.62199775082336 0.0591695377793515 0.444840452559595 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 3/844 20/18639 0.15 3.31261848341232 0.0594169329257309 0.444840452559595 GO:0019239 deaminase activity 4/844 33/18639 0.121212121212121 2.67686342093925 0.0603746542561882 0.444840452559595 GO:0140311 protein sequestering activity 4/844 33/18639 0.121212121212121 2.67686342093925 0.0603746542561882 0.444840452559595 GO:0042562 hormone binding 8/844 94/18639 0.0851063829787234 1.87949984874458 0.0628895348686745 0.459692552492454 GO:0015035 protein-disulfide reductase activity 4/844 34/18639 0.117647058823529 2.5981321438528 0.0660786690002267 0.471543995926322 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 4/844 34/18639 0.117647058823529 2.5981321438528 0.0660786690002267 0.471543995926322 GO:0046332 SMAD binding 7/844 79/18639 0.0886075949367089 1.95682104505369 0.0664268432323428 0.471543995926322 GO:0009931 calcium-dependent protein serine/threonine kinase activity 3/844 21/18639 0.142857142857143 3.15487474610697 0.0670708615269796 0.471543995926322 GO:0072542 protein phosphatase activator activity 3/844 21/18639 0.142857142857143 3.15487474610697 0.0670708615269796 0.471543995926322 GO:0043022 ribosome binding 9/844 112/18639 0.0803571428571429 1.77461704468517 0.0676610898132095 0.472089876651257 GO:0001222 transcription corepressor binding 5/844 49/18639 0.102040816326531 2.25348196150498 0.0697308015403969 0.482651542336837 GO:0005154 epidermal growth factor receptor binding 4/844 35/18639 0.114285714285714 2.52389979688558 0.0720522313370018 0.482651542336837 GO:0004090 carbonyl reductase (NADPH) activity 2/844 10/18639 0.2 4.41682464454976 0.0724061477430498 0.482651542336837 GO:0019911 structural constituent of myelin sheath 2/844 10/18639 0.2 4.41682464454976 0.0724061477430498 0.482651542336837 GO:0043208 glycosphingolipid binding 2/844 10/18639 0.2 4.41682464454976 0.0724061477430498 0.482651542336837 GO:0050815 phosphoserine residue binding 2/844 10/18639 0.2 4.41682464454976 0.0724061477430498 0.482651542336837 GO:0031072 heat shock protein binding 10/844 131/18639 0.0763358778625954 1.68581093303426 0.0738829853918198 0.482651542336837 GO:0001618 virus receptor activity 7/844 81/18639 0.0864197530864197 1.90850447604002 0.073891278468506 0.482651542336837 GO:0030971 receptor tyrosine kinase binding 7/844 81/18639 0.0864197530864197 1.90850447604002 0.073891278468506 0.482651542336837 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/844 22/18639 0.136363636363636 3.01147134855666 0.0751483351196894 0.487405751022774 GO:0140272 exogenous protein binding 7/844 82/18639 0.0853658536585366 1.88523003121026 0.077801497110486 0.501085166704598 GO:0001540 amyloid-beta binding 7/844 83/18639 0.0843373493975904 1.86251641637641 0.0818301258982767 0.510499138054788 GO:0031681 G-protein beta-subunit binding 3/844 23/18639 0.130434782608696 2.88053781166289 0.0836321771803012 0.510499138054788 GO:0030280 structural constituent of skin epidermis 4/844 37/18639 0.108108108108108 2.38747278083771 0.0847892337121784 0.510499138054788 GO:0030159 signaling receptor complex adaptor activity 5/844 52/18639 0.0961538461538462 2.12347338680277 0.0853092784799629 0.510499138054788 GO:0002162 dystroglycan binding 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.510499138054788 GO:0008199 ferric iron binding 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.510499138054788 GO:0008503 benzodiazepine receptor activity 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.510499138054788 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.510499138054788 GO:0019215 intermediate filament binding 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.510499138054788 GO:0043522 leucine zipper domain binding 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.510499138054788 GO:0045294 alpha-catenin binding 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.510499138054788 GO:0140537 transcription regulator activator activity 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.510499138054788 GO:0032934 sterol binding 6/844 68/18639 0.0882352941176471 1.9485991078896 0.0869802263335166 0.5135178746998 GO:0005506 iron ion binding 11/844 154/18639 0.0714285714285714 1.57743737305349 0.0908335216193371 0.526393148482839 GO:0005544 calcium-dependent phospholipid binding 5/844 53/18639 0.0943396226415094 2.08340785120272 0.0908756901289592 0.526393148482839 GO:0016860 intramolecular oxidoreductase activity 5/844 53/18639 0.0943396226415094 2.08340785120272 0.0908756901289592 0.526393148482839 GO:0031267 small GTPase binding 18/844 283/18639 0.0636042402826855 1.40464387989215 0.0929661659193214 0.535136492573094 GO:0015485 cholesterol binding 5/844 54/18639 0.0925925925925926 2.04482622432859 0.0966247141906746 0.545527863479022 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 5/844 54/18639 0.0925925925925926 2.04482622432859 0.0966247141906746 0.545527863479022 GO:0140375 immune receptor activity 11/844 156/18639 0.0705128205128205 1.5572138169887 0.0972460191179378 0.545527863479022 GO:0004859 phospholipase inhibitor activity 2/844 12/18639 0.166666666666667 3.68068720379147 0.100102289824055 0.545527863479022 GO:0005095 GTPase inhibitor activity 2/844 12/18639 0.166666666666667 3.68068720379147 0.100102289824055 0.545527863479022 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 2/844 12/18639 0.166666666666667 3.68068720379147 0.100102289824055 0.545527863479022 GO:0031543 peptidyl-proline dioxygenase activity 2/844 12/18639 0.166666666666667 3.68068720379147 0.100102289824055 0.545527863479022 GO:0035497 cAMP response element binding 2/844 12/18639 0.166666666666667 3.68068720379147 0.100102289824055 0.545527863479022 GO:1990817 poly(A) RNA polymerase activity 2/844 12/18639 0.166666666666667 3.68068720379147 0.100102289824055 0.545527863479022 GO:0003707 nuclear steroid receptor activity 3/844 25/18639 0.12 2.65009478672986 0.101745577018125 0.551221626080546 GO:0061791 GTPase motor activity 4/844 40/18639 0.1 2.20841232227488 0.105782942097224 0.56643075390432 GO:1990606 membrane scission GTPase motor activity 4/844 40/18639 0.1 2.20841232227488 0.105782942097224 0.56643075390432 GO:0020037 heme binding 10/844 142/18639 0.0704225352112676 1.555219945264 0.11086346417265 0.581343881848249 GO:0008198 ferrous iron binding 3/844 26/18639 0.115384615384615 2.54816806416332 0.111336673403041 0.581343881848249 GO:0030507 spectrin binding 3/844 26/18639 0.115384615384615 2.54816806416332 0.111336673403041 0.581343881848249 GO:0070412 R-SMAD binding 3/844 26/18639 0.115384615384615 2.54816806416332 0.111336673403041 0.581343881848249 GO:0042169 SH2 domain binding 4/844 41/18639 0.0975609756097561 2.15454860709745 0.113257556622199 0.581343881848249 GO:0061650 ubiquitin-like protein conjugating enzyme activity 4/844 41/18639 0.0975609756097561 2.15454860709745 0.113257556622199 0.581343881848249 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 2/844 13/18639 0.153846153846154 3.39755741888443 0.11488011563125 0.581343881848249 GO:0019855 calcium channel inhibitor activity 2/844 13/18639 0.153846153846154 3.39755741888443 0.11488011563125 0.581343881848249 GO:0035325 Toll-like receptor binding 2/844 13/18639 0.153846153846154 3.39755741888443 0.11488011563125 0.581343881848249 GO:0140333 glycerophospholipid flippase activity 2/844 13/18639 0.153846153846154 3.39755741888443 0.11488011563125 0.581343881848249 GO:0003924 GTPase activity 20/844 331/18639 0.0604229607250755 1.33438811013588 0.11694039286249 0.588536075553843 GO:0140297 DNA-binding transcription factor binding 28/844 488/18639 0.0573770491803279 1.26712182425608 0.118696236743391 0.591500562739529 GO:0019894 kinesin binding 4/844 42/18639 0.0952380952380952 2.10324983073798 0.120958020161168 0.591500562739529 GO:0051879 Hsp90 protein binding 4/844 42/18639 0.0952380952380952 2.10324983073798 0.120958020161168 0.591500562739529 GO:0004364 glutathione transferase activity 3/844 27/18639 0.111111111111111 2.45379146919431 0.121257555512254 0.591500562739529 GO:0015252 proton channel activity 3/844 27/18639 0.111111111111111 2.45379146919431 0.121257555512254 0.591500562739529 GO:0061980 regulatory RNA binding 5/844 58/18639 0.0862068965517241 1.90380372609904 0.121382851637102 0.591500562739529 GO:0043178 alcohol binding 7/844 92/18639 0.0760869565217391 1.68031372347002 0.123310619439405 0.597732002651012 GO:0051213 dioxygenase activity 7/844 93/18639 0.0752688172043011 1.66224583397034 0.128480949995191 0.616307057008184 GO:0051219 phosphoprotein binding 7/844 93/18639 0.0752688172043011 1.66224583397034 0.128480949995191 0.616307057008184 GO:0005161 platelet-derived growth factor receptor binding 2/844 14/18639 0.142857142857143 3.15487474610697 0.130165715974932 0.617859247508205 GO:0070742 C2H2 zinc finger domain binding 2/844 14/18639 0.142857142857143 3.15487474610697 0.130165715974932 0.617859247508205 GO:0035591 signaling adaptor activity 9/844 129/18639 0.0697674418604651 1.54075278298248 0.131145654460789 0.617859247508205 GO:0046625 sphingolipid binding 3/844 28/18639 0.107142857142857 2.36615605958023 0.131487961467544 0.617859247508205 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 9/844 130/18639 0.0692307692307692 1.52890083849799 0.135621814998526 0.634049196008335 GO:0022804 active transmembrane transporter activity 26/844 457/18639 0.0568927789934354 1.25642714177564 0.137728298153163 0.636768676078497 GO:0003785 actin monomer binding 3/844 29/18639 0.103448275862069 2.28456447131884 0.142007465621651 0.636768676078497 GO:0004181 metallocarboxypeptidase activity 3/844 29/18639 0.103448275862069 2.28456447131884 0.142007465621651 0.636768676078497 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 3/844 29/18639 0.103448275862069 2.28456447131884 0.142007465621651 0.636768676078497 GO:0051861 glycolipid binding 3/844 29/18639 0.103448275862069 2.28456447131884 0.142007465621651 0.636768676078497 GO:0140303 intramembrane lipid transporter activity 4/844 45/18639 0.0888888888888889 1.96303317535545 0.145332138759736 0.636768676078497 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.636768676078497 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.636768676078497 GO:0005523 tropomyosin binding 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.636768676078497 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.636768676078497 GO:0031005 filamin binding 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.636768676078497 GO:0048531 beta-1,3-galactosyltransferase activity 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.636768676078497 GO:0050700 CARD domain binding 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.636768676078497 GO:0051371 muscle alpha-actinin binding 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.636768676078497 GO:0033293 monocarboxylic acid binding 6/844 79/18639 0.0759493670886076 1.67727518147459 0.147773134374734 0.641976682826085 GO:0046906 tetrapyrrole binding 10/844 152/18639 0.0657894736842105 1.4529028436019 0.152097925184277 0.654533685291454 GO:0008106 alcohol dehydrogenase (NADP+) activity 3/844 30/18639 0.1 2.20841232227488 0.152795594286279 0.654533685291454 GO:0048019 receptor antagonist activity 3/844 30/18639 0.1 2.20841232227488 0.152795594286279 0.654533685291454 GO:0042277 peptide binding 15/844 249/18639 0.0602409638554217 1.33036886884029 0.160276519954732 0.662962366038848 GO:1990782 protein tyrosine kinase binding 8/844 117/18639 0.0683760683760684 1.51002551950419 0.160997789440723 0.662962366038848 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/844 16/18639 0.125 2.7605154028436 0.161961490074637 0.662962366038848 GO:0005521 lamin binding 2/844 16/18639 0.125 2.7605154028436 0.161961490074637 0.662962366038848 GO:0019841 retinol binding 2/844 16/18639 0.125 2.7605154028436 0.161961490074637 0.662962366038848 GO:0030275 LRR domain binding 2/844 16/18639 0.125 2.7605154028436 0.161961490074637 0.662962366038848 GO:0034450 ubiquitin-ubiquitin ligase activity 2/844 16/18639 0.125 2.7605154028436 0.161961490074637 0.662962366038848 GO:0055102 lipase inhibitor activity 2/844 16/18639 0.125 2.7605154028436 0.161961490074637 0.662962366038848 GO:0140327 flippase activity 2/844 16/18639 0.125 2.7605154028436 0.161961490074637 0.662962366038848 GO:0140328 floppase activity 2/844 16/18639 0.125 2.7605154028436 0.161961490074637 0.662962366038848 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 20/844 349/18639 0.0573065902578797 1.26556580073059 0.167159377387513 0.681211445017254 GO:0004252 serine-type endopeptidase activity 11/844 176/18639 0.0625 1.3802577014218 0.175438167241416 0.704926752915226 GO:0004550 nucleoside diphosphate kinase activity 2/844 17/18639 0.117647058823529 2.5981321438528 0.178336518381376 0.704926752915226 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/844 17/18639 0.117647058823529 2.5981321438528 0.178336518381376 0.704926752915226 GO:0016805 dipeptidase activity 2/844 17/18639 0.117647058823529 2.5981321438528 0.178336518381376 0.704926752915226 GO:0030548 acetylcholine receptor regulator activity 2/844 17/18639 0.117647058823529 2.5981321438528 0.178336518381376 0.704926752915226 GO:0031489 myosin V binding 2/844 17/18639 0.117647058823529 2.5981321438528 0.178336518381376 0.704926752915226 GO:0045236 CXCR chemokine receptor binding 2/844 17/18639 0.117647058823529 2.5981321438528 0.178336518381376 0.704926752915226 GO:0008238 exopeptidase activity 7/844 102/18639 0.0686274509803922 1.51557708391413 0.17960531956145 0.70690811673545 GO:0005319 lipid transporter activity 11/844 178/18639 0.0617977528089888 1.36474918792268 0.1845735281375 0.721972481414824 GO:0030296 protein tyrosine kinase activator activity 3/844 33/18639 0.0909090909090909 2.00764756570444 0.186568350246176 0.721972481414824 GO:0071889 14-3-3 protein binding 3/844 33/18639 0.0909090909090909 2.00764756570444 0.186568350246176 0.721972481414824 GO:0140416 transcription regulator inhibitor activity 3/844 33/18639 0.0909090909090909 2.00764756570444 0.186568350246176 0.721972481414824 GO:0005548 phospholipid transporter activity 5/844 68/18639 0.0735294117647059 1.623832589908 0.194145946754659 0.73584996731626 GO:0008525 phosphatidylcholine transporter activity 2/844 18/18639 0.111111111111111 2.45379146919431 0.194948308387804 0.73584996731626 GO:0017128 phospholipid scramblase activity 2/844 18/18639 0.111111111111111 2.45379146919431 0.194948308387804 0.73584996731626 GO:0031690 adrenergic receptor binding 2/844 18/18639 0.111111111111111 2.45379146919431 0.194948308387804 0.73584996731626 GO:0035615 clathrin adaptor activity 2/844 18/18639 0.111111111111111 2.45379146919431 0.194948308387804 0.73584996731626 GO:0099602 neurotransmitter receptor regulator activity 2/844 18/18639 0.111111111111111 2.45379146919431 0.194948308387804 0.73584996731626 GO:0030544 Hsp70 protein binding 4/844 51/18639 0.0784313725490196 1.73208809590187 0.199004765644682 0.748095465954089 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 4/844 52/18639 0.0769230769230769 1.69877870944222 0.208479389575075 0.780526495116439 GO:0061631 ubiquitin conjugating enzyme activity 3/844 35/18639 0.0857142857142857 1.89292484766418 0.210057680477404 0.783190027725825 GO:0008301 DNA binding, bending 2/844 19/18639 0.105263157894737 2.32464454976303 0.211741929320011 0.783190027725825 GO:0016918 retinal binding 2/844 19/18639 0.105263157894737 2.32464454976303 0.211741929320011 0.783190027725825 GO:0005496 steroid binding 7/844 108/18639 0.0648148148148148 1.43137835703002 0.217746420253781 0.802177812214928 GO:0004033 aldo-keto reductase (NADPH) activity 3/844 36/18639 0.0833333333333333 1.84034360189573 0.222036486565444 0.81140150673532 GO:0045505 dynein intermediate chain binding 3/844 36/18639 0.0833333333333333 1.84034360189573 0.222036486565444 0.81140150673532 GO:0140793 histone H2AXY142 phosphatase activity 6/844 90/18639 0.0666666666666667 1.47227488151659 0.222893139200908 0.81140150673532 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/844 20/18639 0.1 2.20841232227488 0.228666928919376 0.815721835515571 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 2/844 20/18639 0.1 2.20841232227488 0.228666928919376 0.815721835515571 GO:0016004 phospholipase activator activity 2/844 20/18639 0.1 2.20841232227488 0.228666928919376 0.815721835515571 GO:0016505 peptidase activator activity involved in apoptotic process 2/844 20/18639 0.1 2.20841232227488 0.228666928919376 0.815721835515571 GO:0031418 L-ascorbic acid binding 2/844 20/18639 0.1 2.20841232227488 0.228666928919376 0.815721835515571 GO:0005516 calmodulin binding 12/844 207/18639 0.0579710144927536 1.28023902740573 0.229645478008227 0.815721835515571 GO:0072341 modified amino acid binding 6/844 91/18639 0.0659340659340659 1.45609603666476 0.230279779841529 0.815721835515571 GO:0022829 wide pore channel activity 3/844 37/18639 0.0810810810810811 1.79060458562828 0.234146538287791 0.823087640317007 GO:0023023 MHC protein complex binding 3/844 37/18639 0.0810810810810811 1.79060458562828 0.234146538287791 0.823087640317007 GO:0043539 protein serine/threonine kinase activator activity 5/844 73/18639 0.0684931506849315 1.51261117964033 0.23514393571604 0.823450816709022 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/844 21/18639 0.0952380952380952 2.10324983073798 0.245677041276471 0.849837433148847 GO:0140312 cargo adaptor activity 2/844 21/18639 0.0952380952380952 2.10324983073798 0.245677041276471 0.849837433148847 GO:0005501 retinoid binding 3/844 38/18639 0.0789473684210526 1.74348341232227 0.246369809609926 0.849837433148847 GO:0019840 isoprenoid binding 3/844 38/18639 0.0789473684210526 1.74348341232227 0.246369809609926 0.849837433148847 GO:0019003 GDP binding 5/844 75/18639 0.0666666666666667 1.47227488151659 0.252180974095722 0.863415156662304 GO:0044183 protein folding chaperone 5/844 75/18639 0.0666666666666667 1.47227488151659 0.252180974095722 0.863415156662304 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/844 39/18639 0.0769230769230769 1.69877870944222 0.258688802838908 0.87990635946425 GO:0005243 gap junction channel activity 2/844 22/18639 0.0909090909090909 2.00764756570444 0.262729911892149 0.87990635946425 GO:0008970 phospholipase A1 activity 2/844 22/18639 0.0909090909090909 2.00764756570444 0.262729911892149 0.87990635946425 GO:0031683 G-protein beta/gamma-subunit complex binding 2/844 22/18639 0.0909090909090909 2.00764756570444 0.262729911892149 0.87990635946425 GO:0034062 5'-3' RNA polymerase activity 2/844 22/18639 0.0909090909090909 2.00764756570444 0.262729911892149 0.87990635946425 GO:0097747 RNA polymerase activity 2/844 22/18639 0.0909090909090909 2.00764756570444 0.262729911892149 0.87990635946425 GO:0008236 serine-type peptidase activity 11/844 194/18639 0.0567010309278351 1.2521925538672 0.264712132494102 0.883320191855998 GO:0005126 cytokine receptor binding 15/844 275/18639 0.0545454545454545 1.20458853942266 0.265667419266136 0.883320191855998 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/844 40/18639 0.075 1.65630924170616 0.271086575331477 0.891639026733441 GO:0045309 protein phosphorylated amino acid binding 4/844 59/18639 0.0677966101694915 1.49722869306772 0.277788635028415 0.891639026733441 GO:0019208 phosphatase regulator activity 7/844 117/18639 0.0598290598290598 1.32127232956617 0.279620443889605 0.891639026733441 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/844 23/18639 0.0869565217391304 1.92035854110859 0.279786839007562 0.891639026733441 GO:0004022 alcohol dehydrogenase (NAD+) activity 2/844 23/18639 0.0869565217391304 1.92035854110859 0.279786839007562 0.891639026733441 GO:0004602 glutathione peroxidase activity 2/844 23/18639 0.0869565217391304 1.92035854110859 0.279786839007562 0.891639026733441 GO:0005212 structural constituent of eye lens 2/844 23/18639 0.0869565217391304 1.92035854110859 0.279786839007562 0.891639026733441 GO:0016849 phosphorus-oxygen lyase activity 2/844 23/18639 0.0869565217391304 1.92035854110859 0.279786839007562 0.891639026733441 GO:0017134 fibroblast growth factor binding 2/844 23/18639 0.0869565217391304 1.92035854110859 0.279786839007562 0.891639026733441 GO:0043274 phospholipase binding 2/844 23/18639 0.0869565217391304 1.92035854110859 0.279786839007562 0.891639026733441 GO:0099186 structural constituent of postsynapse 2/844 23/18639 0.0869565217391304 1.92035854110859 0.279786839007562 0.891639026733441 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/844 23/18639 0.0869565217391304 1.92035854110859 0.279786839007562 0.891639026733441 GO:0016922 nuclear receptor binding 8/844 137/18639 0.0583941605839416 1.28958383782475 0.281362448590305 0.891910255472556 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/844 41/18639 0.0731707317073171 1.61591145532308 0.283546761019052 0.891910255472556 GO:0017080 sodium channel regulator activity 3/844 41/18639 0.0731707317073171 1.61591145532308 0.283546761019052 0.891910255472556 GO:0017171 serine hydrolase activity 11/844 198/18639 0.0555555555555556 1.22689573459716 0.286373914748678 0.891910255472556 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 4/844 60/18639 0.0666666666666667 1.47227488151659 0.288004492131037 0.891910255472556 GO:0070851 growth factor receptor binding 8/844 139/18639 0.0575539568345324 1.27102867469058 0.294594615637719 0.891910255472556 GO:0008307 structural constituent of muscle 3/844 42/18639 0.0714285714285714 1.57743737305349 0.296053587238889 0.891910255472556 GO:0031492 nucleosomal DNA binding 3/844 42/18639 0.0714285714285714 1.57743737305349 0.296053587238889 0.891910255472556 GO:0042056 chemoattractant activity 3/844 42/18639 0.0714285714285714 1.57743737305349 0.296053587238889 0.891910255472556 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/844 24/18639 0.0833333333333333 1.84034360189573 0.296812530296179 0.891910255472556 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/844 24/18639 0.0833333333333333 1.84034360189573 0.296812530296179 0.891910255472556 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/844 24/18639 0.0833333333333333 1.84034360189573 0.296812530296179 0.891910255472556 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/844 24/18639 0.0833333333333333 1.84034360189573 0.296812530296179 0.891910255472556 GO:0050431 transforming growth factor beta binding 2/844 24/18639 0.0833333333333333 1.84034360189573 0.296812530296179 0.891910255472556 GO:0050699 WW domain binding 2/844 24/18639 0.0833333333333333 1.84034360189573 0.296812530296179 0.891910255472556 GO:0060229 lipase activator activity 2/844 24/18639 0.0833333333333333 1.84034360189573 0.296812530296179 0.891910255472556 GO:0070840 dynein complex binding 2/844 24/18639 0.0833333333333333 1.84034360189573 0.296812530296179 0.891910255472556 GO:0015026 coreceptor activity 4/844 61/18639 0.0655737704918033 1.44813922772123 0.298271833534796 0.891910255472556 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 4/844 61/18639 0.0655737704918033 1.44813922772123 0.298271833534796 0.891910255472556 GO:0008200 ion channel inhibitor activity 3/844 43/18639 0.0697674418604651 1.54075278298248 0.308591887323709 0.897241305768472 GO:0008375 acetylglucosaminyltransferase activity 3/844 43/18639 0.0697674418604651 1.54075278298248 0.308591887323709 0.897241305768472 GO:0048156 tau protein binding 3/844 43/18639 0.0697674418604651 1.54075278298248 0.308591887323709 0.897241305768472 GO:0008083 growth factor activity 9/844 162/18639 0.0555555555555556 1.22689573459716 0.31302501148527 0.897241305768472 GO:0001848 complement binding 2/844 25/18639 0.08 1.76672985781991 0.313774874059488 0.897241305768472 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/844 25/18639 0.08 1.76672985781991 0.313774874059488 0.897241305768472 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/844 25/18639 0.08 1.76672985781991 0.313774874059488 0.897241305768472 GO:0120020 cholesterol transfer activity 2/844 25/18639 0.08 1.76672985781991 0.313774874059488 0.897241305768472 GO:0016248 channel inhibitor activity 3/844 44/18639 0.0681818181818182 1.50573567427833 0.321147109367602 0.897241305768472 GO:0019205 nucleobase-containing compound kinase activity 3/844 44/18639 0.0681818181818182 1.50573567427833 0.321147109367602 0.897241305768472 GO:0030020 extracellular matrix structural constituent conferring tensile strength 3/844 44/18639 0.0681818181818182 1.50573567427833 0.321147109367602 0.897241305768472 GO:0043014 alpha-tubulin binding 3/844 44/18639 0.0681818181818182 1.50573567427833 0.321147109367602 0.897241305768472 GO:0005543 phospholipid binding 25/844 497/18639 0.0503018108651912 1.11087138947429 0.322205662039492 0.897241305768472 GO:0033218 amide binding 13/844 247/18639 0.0526315789473684 1.16232227488152 0.328854148737988 0.897241305768472 GO:0019865 immunoglobulin binding 2/844 26/18639 0.0769230769230769 1.69877870944222 0.330644724114192 0.897241305768472 GO:0050681 nuclear androgen receptor binding 2/844 26/18639 0.0769230769230769 1.69877870944222 0.330644724114192 0.897241305768472 GO:0097602 cullin family protein binding 2/844 26/18639 0.0769230769230769 1.69877870944222 0.330644724114192 0.897241305768472 GO:0051117 ATPase binding 5/844 84/18639 0.0595238095238095 1.31453114421124 0.331823158496025 0.897241305768472 GO:0004715 non-membrane spanning protein tyrosine kinase activity 3/844 45/18639 0.0666666666666667 1.47227488151659 0.333705321553878 0.897241305768472 GO:0141110 transporter inhibitor activity 3/844 45/18639 0.0666666666666667 1.47227488151659 0.333705321553878 0.897241305768472 GO:0120013 lipid transfer activity 4/844 65/18639 0.0615384615384615 1.35902296755377 0.33968562609455 0.897241305768472 GO:0004180 carboxypeptidase activity 3/844 46/18639 0.0652173913043478 1.44026890583144 0.346253214400574 0.897241305768472 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 3/844 46/18639 0.0652173913043478 1.44026890583144 0.346253214400574 0.897241305768472 GO:0001671 ATPase activator activity 2/844 27/18639 0.0740740740740741 1.63586097946288 0.347395697602347 0.897241305768472 GO:0008320 protein transmembrane transporter activity 2/844 27/18639 0.0740740740740741 1.63586097946288 0.347395697602347 0.897241305768472 GO:0023026 MHC class II protein complex binding 2/844 27/18639 0.0740740740740741 1.63586097946288 0.347395697602347 0.897241305768472 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/844 27/18639 0.0740740740740741 1.63586097946288 0.347395697602347 0.897241305768472 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 5/844 86/18639 0.0581395348837209 1.2839606524854 0.349913255357971 0.897241305768472 GO:0008235 metalloexopeptidase activity 4/844 66/18639 0.0606060606060606 1.33843171046963 0.350084301349033 0.897241305768472 GO:0005525 GTP binding 19/844 378/18639 0.0502645502645503 1.11004852177838 0.352849489777225 0.897241305768472 GO:0019888 protein phosphatase regulator activity 6/844 107/18639 0.0560747663551402 1.23836204987377 0.356111594308382 0.897241305768472 GO:0019001 guanyl nucleotide binding 20/844 400/18639 0.05 1.10420616113744 0.356293426177085 0.897241305768472 GO:0032561 guanyl ribonucleotide binding 20/844 400/18639 0.05 1.10420616113744 0.356293426177085 0.897241305768472 GO:0043495 protein-membrane adaptor activity 3/844 47/18639 0.0638297872340425 1.40962488655843 0.358778100251394 0.897241305768472 GO:0045499 chemorepellent activity 2/844 28/18639 0.0714285714285714 1.57743737305349 0.364003984997332 0.897241305768472 GO:0051393 alpha-actinin binding 2/844 28/18639 0.0714285714285714 1.57743737305349 0.364003984997332 0.897241305768472 GO:0008017 microtubule binding 14/844 276/18639 0.0507246376811594 1.12020914898001 0.370150759645709 0.897241305768472 GO:1990841 promoter-specific chromatin binding 4/844 68/18639 0.0588235294117647 1.2990660719264 0.370881675410509 0.897241305768472 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0003796 lysozyme activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0004955 prostaglandin receptor activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0005131 growth hormone receptor binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0005345 purine nucleobase transmembrane transporter activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0005381 iron ion transmembrane transporter activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0005522 profilin binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0008140 cAMP response element binding protein binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0008239 dipeptidyl-peptidase activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0015187 glycine transmembrane transporter activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0015643 toxic substance binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0016783 sulfurtransferase activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0016868 intramolecular phosphotransferase activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0030957 Tat protein binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0031434 mitogen-activated protein kinase kinase binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0031996 thioesterase binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0032356 oxidized DNA binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0035374 chondroitin sulfate binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0051880 G-quadruplex DNA binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0070513 death domain binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0098505 G-rich strand telomeric DNA binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.897241305768472 GO:0140693 molecular condensate scaffold activity 3/844 48/18639 0.0625 1.3802577014218 0.371267910313884 0.897241305768472 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 5/844 89/18639 0.0561797752808989 1.24068107992971 0.377127780515238 0.897241305768472 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 5/844 89/18639 0.0561797752808989 1.24068107992971 0.377127780515238 0.897241305768472 GO:0004175 endopeptidase activity 20/844 405/18639 0.0493827160493827 1.09057398630858 0.377258075334609 0.897241305768472 GO:0001217 DNA-binding transcription repressor activity 14/844 278/18639 0.0503597122302158 1.11215009035426 0.380324163786212 0.897241305768472 GO:0035250 UDP-galactosyltransferase activity 2/844 29/18639 0.0689655172413793 1.52304298087923 0.380448171617752 0.897241305768472 GO:0002039 p53 binding 4/844 69/18639 0.0579710144927536 1.28023902740573 0.381265777024016 0.897241305768472 GO:0015631 tubulin binding 19/844 385/18639 0.0493506493506494 1.08986582138241 0.383016055253004 0.897241305768472 GO:0016763 pentosyltransferase activity 3/844 49/18639 0.0612244897959184 1.35208917690299 0.383711189522433 0.897241305768472 GO:1902936 phosphatidylinositol bisphosphate binding 6/844 111/18639 0.0540540540540541 1.19373639041885 0.388708632869431 0.897241305768472 GO:0003712 transcription coregulator activity 24/844 495/18639 0.0484848484848485 1.0707453683757 0.39455800426706 0.897241305768472 GO:0004721 phosphoprotein phosphatase activity 9/844 175/18639 0.0514285714285714 1.13575490859851 0.39652387063121 0.897241305768472 GO:0001965 G-protein alpha-subunit binding 2/844 30/18639 0.0666666666666667 1.47227488151659 0.396709069998572 0.897241305768472 GO:0016769 transferase activity, transferring nitrogenous groups 2/844 30/18639 0.0666666666666667 1.47227488151659 0.396709069998572 0.897241305768472 GO:0070566 adenylyltransferase activity 2/844 30/18639 0.0666666666666667 1.47227488151659 0.396709069998572 0.897241305768472 GO:0098918 structural constituent of synapse 2/844 30/18639 0.0666666666666667 1.47227488151659 0.396709069998572 0.897241305768472 GO:0003953 NAD+ nucleosidase activity 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0004954 prostanoid receptor activity 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0005114 type II transforming growth factor beta receptor binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0008172 S-methyltransferase activity 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0008432 JUN kinase binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0008526 phosphatidylinositol transfer activity 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0015173 aromatic amino acid transmembrane transporter activity 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0015205 nucleobase transmembrane transporter activity 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0019107 myristoyltransferase activity 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0019864 IgG binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0032050 clathrin heavy chain binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0032794 GTPase activating protein binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0034056 estrogen response element binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0048407 platelet-derived growth factor binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0050998 nitric-oxide synthase binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0140031 phosphorylation-dependent protein binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:1900750 oligopeptide binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.897241305768472 GO:0016597 amino acid binding 3/844 51/18639 0.0588235294117647 1.2990660719264 0.408415359720959 0.903327029211675 GO:0047499 calcium-independent phospholipase A2 activity 2/844 31/18639 0.0645161290322581 1.42478214340315 0.41276956250398 0.903327029211675 GO:0016779 nucleotidyltransferase activity 7/844 136/18639 0.0514705882352941 1.1366828129356 0.419735663573414 0.903327029211675 GO:0140789 histone phosphatase activity 7/844 136/18639 0.0514705882352941 1.1366828129356 0.419735663573414 0.903327029211675 GO:0004300 enoyl-CoA hydratase activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0005049 nuclear export signal receptor activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0005165 neurotrophin receptor binding 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0005247 voltage-gated chloride channel activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0008603 cAMP-dependent protein kinase regulator activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0015132 prostaglandin transmembrane transporter activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0015166 polyol transmembrane transporter activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0016801 hydrolase activity, acting on ether bonds 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0016803 ether hydrolase activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0016840 carbon-nitrogen lyase activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0017166 vinculin binding 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0043047 single-stranded telomeric DNA binding 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0070410 co-SMAD binding 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.903327029211675 GO:0008378 galactosyltransferase activity 2/844 32/18639 0.0625 1.3802577014218 0.428614453599893 0.903327029211675 GO:0022884 macromolecule transmembrane transporter activity 2/844 32/18639 0.0625 1.3802577014218 0.428614453599893 0.903327029211675 GO:0031369 translation initiation factor binding 2/844 32/18639 0.0625 1.3802577014218 0.428614453599893 0.903327029211675 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/844 32/18639 0.0625 1.3802577014218 0.428614453599893 0.903327029211675 GO:0047498 calcium-dependent phospholipase A2 activity 2/844 32/18639 0.0625 1.3802577014218 0.428614453599893 0.903327029211675 GO:0051059 NF-kappaB binding 2/844 32/18639 0.0625 1.3802577014218 0.428614453599893 0.903327029211675 GO:0048029 monosaccharide binding 4/844 74/18639 0.0540540540540541 1.19373639041885 0.432769885335669 0.9080156543893 GO:0004864 protein phosphatase inhibitor activity 3/844 53/18639 0.0566037735849057 1.25004471072163 0.432810936239851 0.9080156543893 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 9/844 181/18639 0.0497237569060773 1.09810557461182 0.435499916271615 0.910169027878588 GO:0099106 ion channel regulator activity 8/844 160/18639 0.05 1.10420616113744 0.438700813527982 0.910169027878588 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/844 33/18639 0.0606060606060606 1.33843171046963 0.444230331235618 0.910169027878588 GO:0003714 transcription corepressor activity 10/844 204/18639 0.0490196078431373 1.08255505993867 0.444688350561177 0.910169027878588 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/844 54/18639 0.0555555555555556 1.22689573459716 0.444870633091544 0.910169027878588 GO:0050661 NADP binding 3/844 54/18639 0.0555555555555556 1.22689573459716 0.444870633091544 0.910169027878588 GO:0051287 NAD binding 3/844 54/18639 0.0555555555555556 1.22689573459716 0.444870633091544 0.910169027878588 GO:0140463 chromatin-protein adaptor activity 3/844 54/18639 0.0555555555555556 1.22689573459716 0.444870633091544 0.910169027878588 GO:0008253 5'-nucleotidase activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.910169027878588 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.910169027878588 GO:0017154 semaphorin receptor activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.910169027878588 GO:0030955 potassium ion binding 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.910169027878588 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.910169027878588 GO:0045159 myosin II binding 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.910169027878588 GO:0070700 BMP receptor binding 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.910169027878588 GO:0071714 icosanoid transmembrane transporter activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.910169027878588 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.910169027878588 GO:0089720 caspase binding 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.910169027878588 GO:1901338 catecholamine binding 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.910169027878588 GO:0008237 metallopeptidase activity 9/844 184/18639 0.0489130434782609 1.08020167937358 0.454915895248981 0.912582175904597 GO:0004725 protein tyrosine phosphatase activity 5/844 98/18639 0.0510204081632653 1.12674098075249 0.458137868829139 0.912582175904597 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/844 34/18639 0.0588235294117647 1.2990660719264 0.459605436814115 0.912582175904597 GO:1901981 phosphatidylinositol phosphate binding 9/844 185/18639 0.0486486486486487 1.07436275137697 0.46136615913954 0.912582175904597 GO:0019212 phosphatase inhibitor activity 3/844 56/18639 0.0535714285714286 1.18307802979012 0.468673965837958 0.912582175904597 GO:0000287 magnesium ion binding 11/844 230/18639 0.0478260869565217 1.05619719760973 0.470175931652622 0.912582175904597 GO:0004623 phospholipase A2 activity 2/844 35/18639 0.0571428571428571 1.26194989844279 0.474729543258764 0.912582175904597 GO:0016229 steroid dehydrogenase activity 2/844 35/18639 0.0571428571428571 1.26194989844279 0.474729543258764 0.912582175904597 GO:0004065 arylsulfatase activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.912582175904597 GO:0005545 1-phosphatidylinositol binding 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.912582175904597 GO:0008494 translation activator activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.912582175904597 GO:0016530 metallochaperone activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.912582175904597 GO:0019763 immunoglobulin receptor activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.912582175904597 GO:0019992 diacylglycerol binding 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.912582175904597 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.912582175904597 GO:0034236 protein kinase A catalytic subunit binding 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.912582175904597 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.912582175904597 GO:0046030 inositol trisphosphate phosphatase activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.912582175904597 GO:0061783 peptidoglycan muralytic activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.912582175904597 GO:0071933 Arp2/3 complex binding 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.912582175904597 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.912582175904597 GO:0098847 sequence-specific single stranded DNA binding 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.912582175904597 GO:1901612 cardiolipin binding 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.912582175904597 GO:0008528 G protein-coupled peptide receptor activity 6/844 122/18639 0.0491803278688525 1.08610442079093 0.477594580657997 0.912582175904597 GO:0016835 carbon-oxygen lyase activity 4/844 79/18639 0.0506329113924051 1.1181834543164 0.483032588915174 0.921062141596015 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/844 36/18639 0.0555555555555556 1.22689573459716 0.489593840711313 0.931644477882477 GO:0016247 channel regulator activity 8/844 168/18639 0.0476190476190476 1.05162491536899 0.493437509098227 0.932449305013958 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.932449305013958 GO:0004953 icosanoid receptor activity 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.932449305013958 GO:0008242 omega peptidase activity 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.932449305013958 GO:0008252 nucleotidase activity 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.932449305013958 GO:0015250 water channel activity 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.932449305013958 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.932449305013958 GO:0033130 acetylcholine receptor binding 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.932449305013958 GO:0061578 K63-linked deubiquitinase activity 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.932449305013958 GO:0140776 protein-containing complex destabilizing activity 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.932449305013958 GO:0015101 organic cation transmembrane transporter activity 4/844 81/18639 0.0493827160493827 1.09057398630858 0.502645108354949 0.932449305013958 GO:0015459 potassium channel regulator activity 3/844 59/18639 0.0508474576271186 1.12292151980079 0.503484978627368 0.932449305013958 GO:0036002 pre-mRNA binding 3/844 59/18639 0.0508474576271186 1.12292151980079 0.503484978627368 0.932449305013958 GO:0042805 actinin binding 2/844 37/18639 0.0540540540540541 1.19373639041885 0.504190829421228 0.932449305013958 GO:0141108 transporter regulator activity 8/844 170/18639 0.0470588235294118 1.03925285754112 0.506902885427642 0.935586287532782 GO:0000146 microfilament motor activity 2/844 38/18639 0.0526315789473684 1.16232227488152 0.518514219410745 0.936216672561873 GO:0005109 frizzled binding 2/844 38/18639 0.0526315789473684 1.16232227488152 0.518514219410745 0.936216672561873 GO:0005254 chloride channel activity 4/844 83/18639 0.0481927710843374 1.06429509507223 0.521924119636608 0.936216672561873 GO:0008135 translation factor activity, RNA binding 4/844 83/18639 0.0481927710843374 1.06429509507223 0.521924119636608 0.936216672561873 GO:0000062 fatty-acyl-CoA binding 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.936216672561873 GO:0005149 interleukin-1 receptor binding 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.936216672561873 GO:0005159 insulin-like growth factor receptor binding 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.936216672561873 GO:0008142 oxysterol binding 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.936216672561873 GO:0008296 3'-5'-DNA exonuclease activity 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.936216672561873 GO:0016722 oxidoreductase activity, acting on metal ions 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.936216672561873 GO:0017070 U6 snRNA binding 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.936216672561873 GO:0022858 alanine transmembrane transporter activity 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.936216672561873 GO:0043023 ribosomal large subunit binding 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.936216672561873 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.936216672561873 GO:0070411 I-SMAD binding 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.936216672561873 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.936216672561873 GO:0001653 peptide receptor activity 6/844 128/18639 0.046875 1.03519327606635 0.524525301891342 0.936216672561873 GO:0008013 beta-catenin binding 5/844 106/18639 0.0471698113207547 1.04170392560136 0.527489407609476 0.936985497683868 GO:0180051 translation factor activity 4/844 84/18639 0.0476190476190476 1.05162491536899 0.531429167693637 0.936985497683868 GO:0015179 L-amino acid transmembrane transporter activity 3/844 62/18639 0.0483870967741935 1.06858660755236 0.537083669960097 0.936985497683868 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.936985497683868 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.936985497683868 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.936985497683868 GO:0005092 GDP-dissociation inhibitor activity 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.936985497683868 GO:0008484 sulfuric ester hydrolase activity 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.936985497683868 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.936985497683868 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.936985497683868 GO:0019198 transmembrane receptor protein phosphatase activity 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.936985497683868 GO:0030169 low-density lipoprotein particle binding 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.936985497683868 GO:0032977 membrane insertase activity 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.936985497683868 GO:0038191 neuropilin binding 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.936985497683868 GO:0070402 NADPH binding 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.936985497683868 GO:1901567 fatty acid derivative binding 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.936985497683868 GO:1990226 histone methyltransferase binding 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.936985497683868 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/844 40/18639 0.05 1.10420616113744 0.54632053448017 0.936985497683868 GO:0032451 demethylase activity 2/844 40/18639 0.05 1.10420616113744 0.54632053448017 0.936985497683868 GO:0071855 neuropeptide receptor binding 2/844 40/18639 0.05 1.10420616113744 0.54632053448017 0.936985497683868 GO:0140662 ATP-dependent protein folding chaperone 2/844 40/18639 0.05 1.10420616113744 0.54632053448017 0.936985497683868 GO:0016829 lyase activity 9/844 200/18639 0.045 0.993785545023697 0.5556847161888 0.942487884784481 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 12/844 268/18639 0.0447761194029851 0.988841338332036 0.55769747365334 0.942487884784481 GO:0001530 lipopolysaccharide binding 2/844 41/18639 0.0487804878048781 1.07727430354872 0.559796112606382 0.942487884784481 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/844 41/18639 0.0487804878048781 1.07727430354872 0.559796112606382 0.942487884784481 GO:0140318 protein transporter activity 2/844 41/18639 0.0487804878048781 1.07727430354872 0.559796112606382 0.942487884784481 GO:0004222 metalloendopeptidase activity 5/844 110/18639 0.0454545454545455 1.00382378285222 0.560670184029382 0.942487884784481 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.942487884784481 GO:0005372 water transmembrane transporter activity 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.942487884784481 GO:0008308 voltage-gated monoatomic anion channel activity 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.942487884784481 GO:0016854 racemase and epimerase activity 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.942487884784481 GO:0022851 GABA-gated chloride ion channel activity 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.942487884784481 GO:0050811 GABA receptor binding 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.942487884784481 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.942487884784481 GO:0070064 proline-rich region binding 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.942487884784481 GO:1901611 phosphatidylglycerol binding 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.942487884784481 GO:1990381 ubiquitin-specific protease binding 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.942487884784481 GO:0004197 cysteine-type endopeptidase activity 4/844 88/18639 0.0454545454545455 1.00382378285222 0.568476937576555 0.942861877285044 GO:0016853 isomerase activity 8/844 180/18639 0.0444444444444444 0.981516587677725 0.572274099596933 0.942861877285044 GO:0048487 beta-tubulin binding 2/844 42/18639 0.0476190476190476 1.05162491536899 0.572983238874757 0.942861877285044 GO:0003756 protein disulfide isomerase activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0004890 GABA-A receptor activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0005229 intracellularly calcium-gated chloride channel activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0030506 ankyrin binding 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0031420 alkali metal ion binding 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0034987 immunoglobulin receptor binding 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0043395 heparan sulfate proteoglycan binding 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0046624 sphingolipid transporter activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0050145 nucleoside monophosphate kinase activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0097001 ceramide binding 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0120227 acyl-CoA binding 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0140036 ubiquitin-modified protein reader activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0141147 intracellularly calcium-gated channel activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.942861877285044 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3/844 67/18639 0.0447761194029851 0.988841338332036 0.590067602863602 0.948433267429979 GO:0005085 guanyl-nucleotide exchange factor activity 10/844 230/18639 0.0434782608695652 0.960179270554296 0.597725450850485 0.951483367935777 GO:0017124 SH3 domain binding 5/844 115/18639 0.0434782608695652 0.960179270554296 0.600430380879598 0.951483367935777 GO:0035401 histone H3Y41 kinase activity 5/844 115/18639 0.0434782608695652 0.960179270554296 0.600430380879598 0.951483367935777 GO:0140801 histone H2AXY142 kinase activity 5/844 115/18639 0.0434782608695652 0.960179270554296 0.600430380879598 0.951483367935777 GO:0001614 purinergic nucleotide receptor activity 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.951483367935777 GO:0001972 retinoic acid binding 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.951483367935777 GO:0005326 neurotransmitter transmembrane transporter activity 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.951483367935777 GO:0015095 magnesium ion transmembrane transporter activity 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.951483367935777 GO:0016408 C-acyltransferase activity 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.951483367935777 GO:0016502 nucleotide receptor activity 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.951483367935777 GO:0043024 ribosomal small subunit binding 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.951483367935777 GO:0052745 inositol phosphate phosphatase activity 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.951483367935777 GO:0042605 peptide antigen binding 2/844 45/18639 0.0444444444444444 0.981516587677725 0.610802138170825 0.959980834906706 GO:0004713 protein tyrosine kinase activity 6/844 140/18639 0.0428571428571429 0.946462423832092 0.612626089356745 0.961207203232645 GO:0003713 transcription coactivator activity 11/844 256/18639 0.04296875 0.948927169727488 0.613954617296264 0.961653405663026 GO:0016782 transferase activity, transferring sulphur-containing groups 3/844 70/18639 0.0428571428571429 0.946462423832092 0.619918455125261 0.962455955034294 GO:0001846 opsonin binding 1/844 21/18639 0.0476190476190476 1.05162491536899 0.622296667756536 0.962455955034294 GO:0008373 sialyltransferase activity 1/844 21/18639 0.0476190476190476 1.05162491536899 0.622296667756536 0.962455955034294 GO:0009975 cyclase activity 1/844 21/18639 0.0476190476190476 1.05162491536899 0.622296667756536 0.962455955034294 GO:0010314 phosphatidylinositol-5-phosphate binding 1/844 21/18639 0.0476190476190476 1.05162491536899 0.622296667756536 0.962455955034294 GO:0019200 carbohydrate kinase activity 1/844 21/18639 0.0476190476190476 1.05162491536899 0.622296667756536 0.962455955034294 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/844 46/18639 0.0434782608695652 0.960179270554296 0.622827089251291 0.962455955034294 GO:0030276 clathrin binding 2/844 46/18639 0.0434782608695652 0.960179270554296 0.622827089251291 0.962455955034294 GO:0001784 phosphotyrosine residue binding 2/844 47/18639 0.0425531914893617 0.93974992437229 0.634562599873509 0.977311295122912 GO:0099095 ligand-gated monoatomic anion channel activity 2/844 47/18639 0.0425531914893617 0.93974992437229 0.634562599873509 0.977311295122912 GO:0008093 cytoskeletal anchor activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.9773460954813 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.9773460954813 GO:0070034 telomerase RNA binding 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.9773460954813 GO:0140035 ubiquitin-like protein reader activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.9773460954813 GO:0019903 protein phosphatase binding 6/844 144/18639 0.0416666666666667 0.920171800947867 0.639891091829776 0.9773460954813 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 5/844 122/18639 0.040983606557377 0.905087017325771 0.652504788554994 0.983941864008738 GO:0042626 ATPase-coupled transmembrane transporter activity 4/844 98/18639 0.0408163265306122 0.901392784601992 0.65345113209297 0.983941864008738 GO:0003887 DNA-directed DNA polymerase activity 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.983941864008738 GO:0005158 insulin receptor binding 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.983941864008738 GO:0005283 amino acid:sodium symporter activity 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.983941864008738 GO:0016917 GABA receptor activity 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.983941864008738 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.983941864008738 GO:0140103 catalytic activity, acting on a glycoprotein 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.983941864008738 GO:0035254 glutamate receptor binding 2/844 49/18639 0.0408163265306122 0.901392784601992 0.657171854882362 0.983941864008738 GO:0060590 ATPase regulator activity 2/844 49/18639 0.0408163265306122 0.901392784601992 0.657171854882362 0.983941864008738 GO:0031491 nucleosome binding 3/844 74/18639 0.0405405405405405 0.895302292814141 0.657360539464365 0.983941864008738 GO:0005006 epidermal growth factor receptor activity 2/844 50/18639 0.04 0.883364928909953 0.668049970107412 0.983941864008738 GO:0048020 CCR chemokine receptor binding 2/844 50/18639 0.04 0.883364928909953 0.668049970107412 0.983941864008738 GO:0043130 ubiquitin binding 4/844 100/18639 0.04 0.883364928909953 0.669031930789202 0.983941864008738 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.983941864008738 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.983941864008738 GO:0005540 hyaluronic acid binding 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.983941864008738 GO:0030215 semaphorin receptor binding 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.983941864008738 GO:0030552 cAMP binding 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.983941864008738 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.983941864008738 GO:0003823 antigen binding 7/844 174/18639 0.0402298850574713 0.888441738846217 0.678211767913508 0.983941864008738 GO:0016830 carbon-carbon lyase activity 2/844 51/18639 0.0392156862745098 0.866044047950934 0.678647301143593 0.983941864008738 GO:0051540 metal cluster binding 3/844 77/18639 0.038961038961039 0.860420385301902 0.683649604221864 0.983941864008738 GO:0015171 amino acid transmembrane transporter activity 4/844 102/18639 0.0392156862745098 0.866044047950934 0.6841248601285 0.983941864008738 GO:0004709 MAP kinase kinase kinase activity 1/844 25/18639 0.04 0.883364928909953 0.686272369810686 0.983941864008738 GO:0005251 delayed rectifier potassium channel activity 1/844 25/18639 0.04 0.883364928909953 0.686272369810686 0.983941864008738 GO:0008483 transaminase activity 1/844 25/18639 0.04 0.883364928909953 0.686272369810686 0.983941864008738 GO:0015662 P-type ion transporter activity 1/844 25/18639 0.04 0.883364928909953 0.686272369810686 0.983941864008738 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/844 25/18639 0.04 0.883364928909953 0.686272369810686 0.983941864008738 GO:0017025 TBP-class protein binding 1/844 25/18639 0.04 0.883364928909953 0.686272369810686 0.983941864008738 GO:0042974 nuclear retinoic acid receptor binding 1/844 25/18639 0.04 0.883364928909953 0.686272369810686 0.983941864008738 GO:0140358 P-type transmembrane transporter activity 1/844 25/18639 0.04 0.883364928909953 0.686272369810686 0.983941864008738 GO:0004722 protein serine/threonine phosphatase activity 4/844 103/18639 0.0388349514563107 0.857635853310634 0.691487486265584 0.983941864008738 GO:0005253 monoatomic anion channel activity 4/844 103/18639 0.0388349514563107 0.857635853310634 0.691487486265584 0.983941864008738 GO:0031490 chromatin DNA binding 5/844 128/18639 0.0390625 0.862661063388626 0.69354370411857 0.983941864008738 GO:0016791 phosphatase activity 11/844 273/18639 0.0402930402930403 0.889836466850685 0.696630654157049 0.983941864008738 GO:0003774 cytoskeletal motor activity 6/844 153/18639 0.0392156862745098 0.866044047950934 0.696867942488246 0.983941864008738 GO:0005246 calcium channel regulator activity 2/844 53/18639 0.0377358490566038 0.833363140481087 0.699012273158569 0.983941864008738 GO:0008146 sulfotransferase activity 2/844 53/18639 0.0377358490566038 0.833363140481087 0.699012273158569 0.983941864008738 GO:0017046 peptide hormone binding 2/844 53/18639 0.0377358490566038 0.833363140481087 0.699012273158569 0.983941864008738 GO:0051018 protein kinase A binding 2/844 53/18639 0.0377358490566038 0.833363140481087 0.699012273158569 0.983941864008738 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.983941864008738 GO:0004529 DNA exonuclease activity 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.983941864008738 GO:0005112 Notch binding 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.983941864008738 GO:0005160 transforming growth factor beta receptor binding 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.983941864008738 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.983941864008738 GO:0050750 low-density lipoprotein particle receptor binding 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.983941864008738 GO:0070006 metalloaminopeptidase activity 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.983941864008738 GO:0120014 phospholipid transfer activity 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.983941864008738 GO:0030695 GTPase regulator activity 20/844 489/18639 0.0408997955010225 0.903236123629808 0.712646171186945 0.983941864008738 GO:0004497 monooxygenase activity 4/844 106/18639 0.0377358490566038 0.833363140481087 0.712838673127054 0.983941864008738 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/844 27/18639 0.037037037037037 0.817930489731438 0.714078313255322 0.983941864008738 GO:0008395 steroid hydroxylase activity 1/844 27/18639 0.037037037037037 0.817930489731438 0.714078313255322 0.983941864008738 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/844 27/18639 0.037037037037037 0.817930489731438 0.714078313255322 0.983941864008738 GO:0035255 ionotropic glutamate receptor binding 1/844 27/18639 0.037037037037037 0.817930489731438 0.714078313255322 0.983941864008738 GO:0060589 nucleoside-triphosphatase regulator activity 20/844 490/18639 0.0408163265306122 0.901392784601992 0.715970386601502 0.983941864008738 GO:0033192 calmodulin-dependent protein phosphatase activity 3/844 81/18639 0.037037037037037 0.817930489731438 0.71631872448086 0.983941864008738 GO:0140791 histone H2AXS140 phosphatase activity 3/844 81/18639 0.037037037037037 0.817930489731438 0.71631872448086 0.983941864008738 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 3/844 81/18639 0.037037037037037 0.817930489731438 0.71631872448086 0.983941864008738 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 3/844 81/18639 0.037037037037037 0.817930489731438 0.71631872448086 0.983941864008738 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 3/844 81/18639 0.037037037037037 0.817930489731438 0.71631872448086 0.983941864008738 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 3/844 81/18639 0.037037037037037 0.817930489731438 0.71631872448086 0.983941864008738 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 3/844 81/18639 0.037037037037037 0.817930489731438 0.71631872448086 0.983941864008738 GO:1990439 MAP kinase serine/threonine phosphatase activity 3/844 81/18639 0.037037037037037 0.817930489731438 0.71631872448086 0.983941864008738 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 5/844 132/18639 0.0378787878787879 0.836519819043516 0.71899174278035 0.983941864008738 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 3/844 82/18639 0.0365853658536585 0.807955727661542 0.724065198669008 0.983941864008738 GO:0033549 MAP kinase phosphatase activity 3/844 82/18639 0.0365853658536585 0.807955727661542 0.724065198669008 0.983941864008738 GO:0005242 inward rectifier potassium channel activity 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.983941864008738 GO:0016866 intramolecular transferase activity 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.983941864008738 GO:0019789 SUMO transferase activity 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.983941864008738 GO:0046875 ephrin receptor binding 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.983941864008738 GO:0046966 nuclear thyroid hormone receptor binding 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.983941864008738 GO:0051019 mitogen-activated protein kinase binding 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.983941864008738 GO:0051959 dynein light intermediate chain binding 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.983941864008738 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.983941864008738 GO:0097718 disordered domain specific binding 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.983941864008738 GO:0141052 histone H3 demethylase activity 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.983941864008738 GO:0170055 lipid transmembrane transporter activity 2/844 56/18639 0.0357142857142857 0.788718686526743 0.727540075341966 0.983941864008738 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 3/844 83/18639 0.036144578313253 0.798221321304174 0.731645489132723 0.986596625902252 GO:0030165 PDZ domain binding 3/844 83/18639 0.036144578313253 0.798221321304174 0.731645489132723 0.986596625902252 GO:0016504 peptidase activator activity 2/844 57/18639 0.0350877192982456 0.774881516587678 0.736526869036517 0.99172696839566 GO:0017018 myosin phosphatase activity 3/844 84/18639 0.0357142857142857 0.788718686526743 0.739060908445282 0.992723147002227 GO:0005416 amino acid:monoatomic cation symporter activity 1/844 29/18639 0.0344827586206897 0.761521490439614 0.739422452598836 0.992723147002227 GO:0035091 phosphatidylinositol binding 11/844 284/18639 0.0387323943661972 0.8553709698952 0.743917292807418 0.997303968960163 GO:0008234 cysteine-type peptidase activity 7/844 187/18639 0.0374331550802139 0.82667840940771 0.747836627226892 0.998845008246091 GO:0031624 ubiquitin conjugating enzyme binding 1/844 30/18639 0.0333333333333333 0.736137440758294 0.751240155447121 0.998845008246091 GO:0032452 histone demethylase activity 1/844 30/18639 0.0333333333333333 0.736137440758294 0.751240155447121 0.998845008246091 GO:0033612 receptor serine/threonine kinase binding 1/844 30/18639 0.0333333333333333 0.736137440758294 0.751240155447121 0.998845008246091 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/844 30/18639 0.0333333333333333 0.736137440758294 0.751240155447121 0.998845008246091 GO:0050660 flavin adenine dinucleotide binding 3/844 86/18639 0.0348837209302326 0.770376391491238 0.753402990220669 0.998845008246091 GO:0031593 polyubiquitin modification-dependent protein binding 2/844 59/18639 0.0338983050847458 0.748614346533858 0.753742975820883 0.998845008246091 GO:0070888 E-box binding 2/844 59/18639 0.0338983050847458 0.748614346533858 0.753742975820883 0.998845008246091 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/844 60/18639 0.0333333333333333 0.736137440758294 0.761981490267671 0.999990337535948 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/844 60/18639 0.0333333333333333 0.736137440758294 0.761981490267671 0.999990337535948 GO:0005164 tumor necrosis factor receptor binding 1/844 31/18639 0.032258064516129 0.712391071701575 0.762522508545225 0.999990337535948 GO:0005184 neuropeptide hormone activity 1/844 31/18639 0.032258064516129 0.712391071701575 0.762522508545225 0.999990337535948 GO:0070325 lipoprotein particle receptor binding 1/844 31/18639 0.032258064516129 0.712391071701575 0.762522508545225 0.999990337535948 GO:0072349 modified amino acid transmembrane transporter activity 1/844 31/18639 0.032258064516129 0.712391071701575 0.762522508545225 0.999990337535948 GO:0140457 protein demethylase activity 1/844 31/18639 0.032258064516129 0.712391071701575 0.762522508545225 0.999990337535948 GO:0016836 hydro-lyase activity 2/844 61/18639 0.0327868852459016 0.724069613860617 0.769979942907896 0.999990337535948 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 19/844 484/18639 0.0392561983471074 0.866938721554189 0.771316184707979 0.999990337535948 GO:0030515 snoRNA binding 1/844 32/18639 0.03125 0.6901288507109 0.773293736124107 0.999990337535948 GO:0071813 lipoprotein particle binding 1/844 32/18639 0.03125 0.6901288507109 0.773293736124107 0.999990337535948 GO:0071814 protein-lipid complex binding 1/844 32/18639 0.03125 0.6901288507109 0.773293736124107 0.999990337535948 GO:0140142 nucleocytoplasmic carrier activity 1/844 32/18639 0.03125 0.6901288507109 0.773293736124107 0.999990337535948 GO:0160041 neuropeptide activity 1/844 32/18639 0.03125 0.6901288507109 0.773293736124107 0.999990337535948 GO:0003727 single-stranded RNA binding 3/844 89/18639 0.0337078651685393 0.744408647957825 0.773718985104559 0.999990337535948 GO:0042923 neuropeptide binding 1/844 33/18639 0.0303030303030303 0.669215855234813 0.783576967526872 0.999990337535948 GO:0001216 DNA-binding transcription activator activity 19/844 491/18639 0.0386965376782077 0.854579106379282 0.791385521154021 0.999990337535948 GO:0004536 DNA nuclease activity 2/844 64/18639 0.03125 0.6901288507109 0.792583379187136 0.999990337535948 GO:0008376 acetylgalactosaminyltransferase activity 1/844 34/18639 0.0294117647058824 0.6495330359632 0.79339428663938 0.999990337535948 GO:0016831 carboxy-lyase activity 1/844 34/18639 0.0294117647058824 0.6495330359632 0.79339428663938 0.999990337535948 GO:0030332 cyclin binding 1/844 34/18639 0.0294117647058824 0.6495330359632 0.79339428663938 0.999990337535948 GO:0051427 hormone receptor binding 1/844 34/18639 0.0294117647058824 0.6495330359632 0.79339428663938 0.999990337535948 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/844 34/18639 0.0294117647058824 0.6495330359632 0.79339428663938 0.999990337535948 GO:0090482 vitamin transmembrane transporter activity 1/844 34/18639 0.0294117647058824 0.6495330359632 0.79339428663938 0.999990337535948 GO:0032182 ubiquitin-like protein binding 4/844 120/18639 0.0333333333333333 0.736137440758294 0.79814241039301 0.999990337535948 GO:0140104 molecular carrier activity 9/844 249/18639 0.036144578313253 0.798221321304174 0.799544322505983 0.999990337535948 GO:0005244 voltage-gated monoatomic ion channel activity 6/844 173/18639 0.0346820809248555 0.765923348765855 0.800695655833393 0.999990337535948 GO:0000175 3'-5'-RNA exonuclease activity 1/844 35/18639 0.0285714285714286 0.630974949221395 0.802766779091751 0.999990337535948 GO:0005343 organic acid:sodium symporter activity 1/844 35/18639 0.0285714285714286 0.630974949221395 0.802766779091751 0.999990337535948 GO:0034061 DNA polymerase activity 1/844 35/18639 0.0285714285714286 0.630974949221395 0.802766779091751 0.999990337535948 GO:0015108 chloride transmembrane transporter activity 4/844 121/18639 0.0330578512396694 0.730053660256159 0.803366549640236 0.999990337535948 GO:0016410 N-acyltransferase activity 3/844 94/18639 0.0319148936170213 0.704812443279217 0.804512636509569 0.999990337535948 GO:0022832 voltage-gated channel activity 6/844 175/18639 0.0342857142857143 0.757169939065674 0.809369527090772 0.999990337535948 GO:0004190 aspartic-type endopeptidase activity 1/844 36/18639 0.0277777777777778 0.613447867298578 0.811714577331192 0.999990337535948 GO:0005484 SNAP receptor activity 1/844 36/18639 0.0277777777777778 0.613447867298578 0.811714577331192 0.999990337535948 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/844 36/18639 0.0277777777777778 0.613447867298578 0.811714577331192 0.999990337535948 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/844 36/18639 0.0277777777777778 0.613447867298578 0.811714577331192 0.999990337535948 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/844 36/18639 0.0277777777777778 0.613447867298578 0.811714577331192 0.999990337535948 GO:0019842 vitamin binding 5/844 150/18639 0.0333333333333333 0.736137440758294 0.814712375796507 0.999990337535948 GO:0005267 potassium channel activity 4/844 124/18639 0.032258064516129 0.712391071701575 0.818382986989675 0.999990337535948 GO:0030551 cyclic nucleotide binding 1/844 37/18639 0.027027027027027 0.596868195209427 0.820256903662024 0.999990337535948 GO:0070001 aspartic-type peptidase activity 1/844 37/18639 0.027027027027027 0.596868195209427 0.820256903662024 0.999990337535948 GO:0005249 voltage-gated potassium channel activity 3/844 98/18639 0.0306122448979592 0.676044588451494 0.826540315297578 0.999990337535948 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/844 38/18639 0.0263157894736842 0.581161137440758 0.828412111344491 0.999990337535948 GO:0042162 telomeric DNA binding 1/844 38/18639 0.0263157894736842 0.581161137440758 0.828412111344491 0.999990337535948 GO:0042887 amide transmembrane transporter activity 1/844 38/18639 0.0263157894736842 0.581161137440758 0.828412111344491 0.999990337535948 GO:0043531 ADP binding 1/844 38/18639 0.0263157894736842 0.581161137440758 0.828412111344491 0.999990337535948 GO:0097110 scaffold protein binding 2/844 70/18639 0.0285714285714286 0.630974949221395 0.831970464149552 0.999990337535948 GO:0000217 DNA secondary structure binding 1/844 39/18639 0.0256410256410256 0.566259569814072 0.836197723839801 0.999990337535948 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/844 39/18639 0.0256410256410256 0.566259569814072 0.836197723839801 0.999990337535948 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/844 39/18639 0.0256410256410256 0.566259569814072 0.836197723839801 0.999990337535948 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 4/844 128/18639 0.03125 0.6901288507109 0.836923754241438 0.999990337535948 GO:0004177 aminopeptidase activity 1/844 40/18639 0.025 0.55210308056872 0.843630472284919 0.999990337535948 GO:0004532 RNA exonuclease activity 1/844 40/18639 0.025 0.55210308056872 0.843630472284919 0.999990337535948 GO:0015144 carbohydrate transmembrane transporter activity 1/844 40/18639 0.025 0.55210308056872 0.843630472284919 0.999990337535948 GO:0030331 nuclear estrogen receptor binding 1/844 40/18639 0.025 0.55210308056872 0.843630472284919 0.999990337535948 GO:0050997 quaternary ammonium group binding 1/844 40/18639 0.025 0.55210308056872 0.843630472284919 0.999990337535948 GO:0071949 FAD binding 1/844 40/18639 0.025 0.55210308056872 0.843630472284919 0.999990337535948 GO:0004520 DNA endonuclease activity 1/844 42/18639 0.0238095238095238 0.525812457684496 0.857500553042788 0.999990337535948 GO:0016859 cis-trans isomerase activity 1/844 42/18639 0.0238095238095238 0.525812457684496 0.857500553042788 0.999990337535948 GO:0016757 glycosyltransferase activity 9/844 267/18639 0.0337078651685393 0.744408647957825 0.858618868361455 0.999990337535948 GO:0005245 voltage-gated calcium channel activity 1/844 43/18639 0.0232558139534884 0.513584260994159 0.863967700068217 0.999990337535948 GO:0000149 SNARE binding 3/844 106/18639 0.0283018867924528 0.625022355360816 0.864271182035888 0.999990337535948 GO:0051536 iron-sulfur cluster binding 2/844 76/18639 0.0263157894736842 0.581161137440758 0.864481019496273 0.999990337535948 GO:0019902 phosphatase binding 6/844 190/18639 0.0315789473684211 0.69739336492891 0.865293560506892 0.999990337535948 GO:0099094 ligand-gated monoatomic cation channel activity 4/844 136/18639 0.0294117647058824 0.6495330359632 0.869268622281261 0.999990337535948 GO:0003724 RNA helicase activity 2/844 77/18639 0.025974025974026 0.573613590201268 0.869303190570257 0.999990337535948 GO:0001223 transcription coactivator binding 1/844 44/18639 0.0227272727272727 0.501911891426109 0.870141676253548 0.999990337535948 GO:0019199 transmembrane receptor protein kinase activity 2/844 78/18639 0.0256410256410256 0.566259569814072 0.873967192223456 0.999990337535948 GO:0046915 transition metal ion transmembrane transporter activity 1/844 45/18639 0.0222222222222222 0.490758293838863 0.876035756664519 0.999990337535948 GO:0051539 4 iron, 4 sulfur cluster binding 1/844 45/18639 0.0222222222222222 0.490758293838863 0.876035756664519 0.999990337535948 GO:0008186 ATP-dependent activity, acting on RNA 2/844 79/18639 0.0253164556962025 0.559091727158198 0.87847744009891 0.999990337535948 GO:0000049 tRNA binding 2/844 80/18639 0.025 0.55210308056872 0.882838274797688 0.999990337535948 GO:0140359 ABC-type transporter activity 1/844 47/18639 0.0212765957446809 0.469874962186145 0.887034355420083 0.999990337535948 GO:0008188 neuropeptide receptor activity 1/844 48/18639 0.0208333333333333 0.460085900473934 0.892162529044516 0.999990337535948 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/844 48/18639 0.0208333333333333 0.460085900473934 0.892162529044516 0.999990337535948 GO:0032266 phosphatidylinositol-3-phosphate binding 1/844 48/18639 0.0208333333333333 0.460085900473934 0.892162529044516 0.999990337535948 GO:0038187 pattern recognition receptor activity 1/844 48/18639 0.0208333333333333 0.460085900473934 0.892162529044516 0.999990337535948 GO:0022843 voltage-gated monoatomic cation channel activity 4/844 143/18639 0.027972027972028 0.617737712524442 0.892887541440709 0.999990337535948 GO:0005004 GPI-linked ephrin receptor activity 1/844 49/18639 0.0204081632653061 0.450696392300996 0.89705816808956 0.999990337535948 GO:0005008 hepatocyte growth factor receptor activity 1/844 49/18639 0.0204081632653061 0.450696392300996 0.89705816808956 0.999990337535948 GO:0005009 insulin receptor activity 1/844 49/18639 0.0204081632653061 0.450696392300996 0.89705816808956 0.999990337535948 GO:0005011 macrophage colony-stimulating factor receptor activity 1/844 49/18639 0.0204081632653061 0.450696392300996 0.89705816808956 0.999990337535948 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/844 49/18639 0.0204081632653061 0.450696392300996 0.89705816808956 0.999990337535948 GO:0005020 stem cell factor receptor activity 1/844 49/18639 0.0204081632653061 0.450696392300996 0.89705816808956 0.999990337535948 GO:0008288 boss receptor activity 1/844 49/18639 0.0204081632653061 0.450696392300996 0.89705816808956 0.999990337535948 GO:0036332 placental growth factor receptor activity 1/844 49/18639 0.0204081632653061 0.450696392300996 0.89705816808956 0.999990337535948 GO:0038062 protein tyrosine kinase collagen receptor activity 1/844 49/18639 0.0204081632653061 0.450696392300996 0.89705816808956 0.999990337535948 GO:0060175 brain-derived neurotrophic factor receptor activity 1/844 49/18639 0.0204081632653061 0.450696392300996 0.89705816808956 0.999990337535948 GO:0008194 UDP-glycosyltransferase activity 4/844 145/18639 0.0275862068965517 0.609217192351691 0.898910466699651 0.999990337535948 GO:0042578 phosphoric ester hydrolase activity 12/844 363/18639 0.0330578512396694 0.730053660256159 0.900858367172389 0.999990337535948 GO:0005007 fibroblast growth factor receptor activity 1/844 50/18639 0.02 0.441682464454976 0.901731804783074 0.999990337535948 GO:0005017 platelet-derived growth factor receptor activity 1/844 50/18639 0.02 0.441682464454976 0.901731804783074 0.999990337535948 GO:0005019 platelet-derived growth factor beta-receptor activity 1/844 50/18639 0.02 0.441682464454976 0.901731804783074 0.999990337535948 GO:0032813 tumor necrosis factor receptor superfamily binding 1/844 50/18639 0.02 0.441682464454976 0.901731804783074 0.999990337535948 GO:0003743 translation initiation factor activity 1/844 51/18639 0.0196078431372549 0.433022023975467 0.906193494855863 0.999990337535948 GO:0005010 insulin-like growth factor receptor activity 1/844 51/18639 0.0196078431372549 0.433022023975467 0.906193494855863 0.999990337535948 GO:0005021 vascular endothelial growth factor receptor activity 1/844 51/18639 0.0196078431372549 0.433022023975467 0.906193494855863 0.999990337535948 GO:0005030 neurotrophin receptor activity 1/844 51/18639 0.0196078431372549 0.433022023975467 0.906193494855863 0.999990337535948 GO:0005261 monoatomic cation channel activity 11/844 341/18639 0.032258064516129 0.712391071701575 0.908684044871763 0.999990337535948 GO:0008509 monoatomic anion transmembrane transporter activity 4/844 149/18639 0.0268456375838926 0.592862368395941 0.910067105534707 0.999990337535948 GO:0005216 monoatomic ion channel activity 15/844 448/18639 0.0334821428571429 0.739423768618822 0.913486589984962 0.999990337535948 GO:0005003 ephrin receptor activity 1/844 53/18639 0.0188679245283019 0.416681570240544 0.914519003803961 0.999990337535948 GO:0005005 transmembrane-ephrin receptor activity 1/844 53/18639 0.0188679245283019 0.416681570240544 0.914519003803961 0.999990337535948 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/844 53/18639 0.0188679245283019 0.416681570240544 0.914519003803961 0.999990337535948 GO:0038064 collagen receptor activity 1/844 53/18639 0.0188679245283019 0.416681570240544 0.914519003803961 0.999990337535948 GO:0140296 general transcription initiation factor binding 1/844 53/18639 0.0188679245283019 0.416681570240544 0.914519003803961 0.999990337535948 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/844 53/18639 0.0188679245283019 0.416681570240544 0.914519003803961 0.999990337535948 GO:0003697 single-stranded DNA binding 3/844 121/18639 0.0247933884297521 0.547540245192119 0.91597091860279 0.999990337535948 GO:0003925 G protein activity 1/844 54/18639 0.0185185185185185 0.408965244865719 0.91840074063757 0.999990337535948 GO:0017069 snRNA binding 1/844 54/18639 0.0185185185185185 0.408965244865719 0.91840074063757 0.999990337535948 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/844 122/18639 0.0245901639344262 0.543052210395463 0.918680760895891 0.999990337535948 GO:0008374 O-acyltransferase activity 1/844 55/18639 0.0181818181818182 0.401529513140888 0.922106405146685 0.999990337535948 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/844 56/18639 0.0178571428571429 0.394359343263372 0.925643974779498 0.999990337535948 GO:0015276 ligand-gated monoatomic ion channel activity 5/844 186/18639 0.0268817204301075 0.593659226417979 0.927754387698984 0.999990337535948 GO:0005096 GTPase activator activity 8/844 271/18639 0.029520295202952 0.651929836833913 0.927820194418047 0.999990337535948 GO:0019783 ubiquitin-like protein peptidase activity 3/844 127/18639 0.0236220472440945 0.521672202112177 0.931070189501589 0.999990337535948 GO:0042826 histone deacetylase binding 3/844 127/18639 0.0236220472440945 0.521672202112177 0.931070189501589 0.999990337535948 GO:0022834 ligand-gated channel activity 5/844 188/18639 0.0265957446808511 0.587343702732681 0.931684266027924 0.999990337535948 GO:0008408 3'-5' exonuclease activity 1/844 58/18639 0.0172413793103448 0.380760745219807 0.932244950375784 0.999990337535948 GO:0140996 histone H3 kinase activity 11/844 357/18639 0.030812324929972 0.680463180532877 0.934403703738158 0.999990337535948 GO:0015079 potassium ion transmembrane transporter activity 4/844 160/18639 0.025 0.55210308056872 0.935304210498956 0.999990337535948 GO:0070063 RNA polymerase binding 1/844 59/18639 0.0169491525423729 0.374307173266929 0.935322570626731 0.999990337535948 GO:0030594 neurotransmitter receptor activity 2/844 97/18639 0.0206185567010309 0.4553427468608 0.937925205842015 0.999990337535948 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/844 60/18639 0.0166666666666667 0.368068720379147 0.938260555039596 0.999990337535948 GO:0035173 histone kinase activity 11/844 360/18639 0.0305555555555556 0.674792654028436 0.938460988644162 0.999990337535948 GO:0019905 syntaxin binding 1/844 61/18639 0.0163934426229508 0.362034806930308 0.941065231908458 0.999990337535948 GO:0005179 hormone activity 3/844 132/18639 0.0227272727272727 0.501911891426109 0.941701444337266 0.999990337535948 GO:0015103 inorganic anion transmembrane transporter activity 4/844 165/18639 0.0242424242424242 0.53537268418785 0.944496019391149 0.999990337535948 GO:0022824 transmitter-gated monoatomic ion channel activity 1/844 63/18639 0.0158730158730159 0.35054163845633 0.946298556779008 0.999990337535948 GO:0022835 transmitter-gated channel activity 1/844 63/18639 0.0158730158730159 0.35054163845633 0.946298556779008 0.999990337535948 GO:0016758 hexosyltransferase activity 5/844 197/18639 0.0253807106598985 0.560510741694132 0.947103671007807 0.999990337535948 GO:0140767 enzyme-substrate adaptor activity 3/844 139/18639 0.0215827338129496 0.476635753008967 0.954048702063471 0.999990337535948 GO:0003730 mRNA 3'-UTR binding 7/844 262/18639 0.0267175572519084 0.590033826561991 0.955275980186516 0.999990337535948 GO:0016500 protein-hormone receptor activity 1/844 67/18639 0.0149253731343284 0.329613779444012 0.955413707505267 0.999990337535948 GO:0030145 manganese ion binding 1/844 68/18639 0.0147058823529412 0.3247665179816 0.957439920668392 0.999990337535948 GO:0140223 general transcription initiation factor activity 1/844 68/18639 0.0147058823529412 0.3247665179816 0.957439920668392 0.999990337535948 GO:0004843 cysteine-type deubiquitinase activity 2/844 108/18639 0.0185185185185185 0.408965244865719 0.959333134852261 0.999990337535948 GO:0098960 postsynaptic neurotransmitter receptor activity 1/844 69/18639 0.0144927536231884 0.320059756851432 0.959374157217629 0.999990337535948 GO:0004620 phospholipase activity 2/844 109/18639 0.018348623853211 0.40521327014218 0.960882476100096 0.999990337535948 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/844 70/18639 0.0142857142857143 0.315487474610697 0.961220587551949 0.999990337535948 GO:0141003 histone H2AX kinase activity 10/844 354/18639 0.0282485875706215 0.623845288778215 0.962003788150716 0.999990337535948 GO:0140299 molecular sensor activity 1/844 71/18639 0.0140845070422535 0.3110439890528 0.96298319319071 0.999990337535948 GO:0015293 symporter activity 3/844 146/18639 0.0205479452054795 0.453783353892099 0.963917203894743 0.999990337535948 GO:0015085 calcium ion transmembrane transporter activity 3/844 147/18639 0.0204081632653061 0.450696392300996 0.965152290305535 0.999990337535948 GO:0004521 RNA endonuclease activity 1/844 73/18639 0.0136986301369863 0.302522235928066 0.966271962943291 0.999990337535948 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/844 73/18639 0.0136986301369863 0.302522235928066 0.966271962943291 0.999990337535948 GO:0003684 damaged DNA binding 1/844 74/18639 0.0135135135135135 0.298434097604714 0.967805220687332 0.999990337535948 GO:0101005 deubiquitinase activity 2/844 115/18639 0.0173913043478261 0.384071708221718 0.969053862842927 0.999990337535948 GO:0003725 double-stranded RNA binding 1/844 75/18639 0.0133333333333333 0.294454976303318 0.969268856224089 0.999990337535948 GO:0000510 H3-H4 histone complex chaperone activity 3/844 151/18639 0.0198675496688742 0.4387574150215 0.969705180096709 0.999990337535948 GO:0140584 chromatin extrusion motor activity 3/844 151/18639 0.0198675496688742 0.4387574150215 0.969705180096709 0.999990337535948 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/844 151/18639 0.0198675496688742 0.4387574150215 0.969705180096709 0.999990337535948 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/844 151/18639 0.0198675496688742 0.4387574150215 0.969705180096709 0.999990337535948 GO:0035402 histone H3T11 kinase activity 6/844 247/18639 0.0242914979757085 0.5364564345607 0.970013834743293 0.999990337535948 GO:0035403 histone H3T6 kinase activity 6/844 247/18639 0.0242914979757085 0.5364564345607 0.970013834743293 0.999990337535948 GO:0015616 DNA translocase activity 3/844 152/18639 0.0197368421052632 0.435870853080569 0.970752213774119 0.999990337535948 GO:0140674 ATP-dependent histone chaperone activity 3/844 152/18639 0.0197368421052632 0.435870853080569 0.970752213774119 0.999990337535948 GO:0061775 cohesin loader activity 3/844 153/18639 0.0196078431372549 0.433022023975467 0.971764941764339 0.999990337535948 GO:0046943 carboxylic acid transmembrane transporter activity 4/844 188/18639 0.0212765957446809 0.469874962186145 0.973253788553473 0.999990337535948 GO:0140597 protein carrier chaperone 4/844 188/18639 0.0212765957446809 0.469874962186145 0.973253788553473 0.999990337535948 GO:0005342 organic acid transmembrane transporter activity 4/844 189/18639 0.0211640211640212 0.467388851275107 0.974111670260548 0.999990337535948 GO:0015370 solute:sodium symporter activity 1/844 79/18639 0.0126582278481013 0.279545863579099 0.974488225400595 0.999990337535948 GO:0004540 RNA nuclease activity 2/844 121/18639 0.0165289256198347 0.36502683012808 0.975568139010914 0.999990337535948 GO:0140658 ATP-dependent chromatin remodeler activity 3/844 158/18639 0.0189873417721519 0.419318795368648 0.976349323411711 0.999990337535948 GO:0003689 DNA clamp loader activity 3/844 160/18639 0.01875 0.41407731042654 0.977977163283196 0.999990337535948 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 5/844 229/18639 0.0218340611353712 0.482186096566568 0.979714284026714 0.999990337535948 GO:0004527 exonuclease activity 1/844 84/18639 0.0119047619047619 0.262906228842248 0.979785266586379 0.999990337535948 GO:0004519 endonuclease activity 2/844 127/18639 0.015748031496063 0.347781468074784 0.980747305212826 0.999990337535948 GO:0140713 histone chaperone activity 3/844 164/18639 0.0182926829268293 0.403977863830771 0.980918382890787 0.999990337535948 GO:0008081 phosphoric diester hydrolase activity 1/844 87/18639 0.0114942528735632 0.253840496813205 0.982420316778136 0.999990337535948 GO:0016874 ligase activity 3/844 167/18639 0.0179640718562874 0.396720776456566 0.982874152952708 0.999990337535948 GO:0016298 lipase activity 2/844 130/18639 0.0153846153846154 0.339755741888443 0.98292059015402 0.999990337535948 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/844 130/18639 0.0153846153846154 0.339755741888443 0.98292059015402 0.999990337535948 GO:0016887 ATP hydrolysis activity 11/844 417/18639 0.026378896882494 0.582554809233182 0.983432478301006 0.999990337535948 GO:0005262 calcium channel activity 2/844 131/18639 0.0152671755725191 0.337162186606852 0.983590600605995 0.999990337535948 GO:0106310 protein serine kinase activity 9/844 361/18639 0.0249307479224377 0.550573709154403 0.984445542207115 0.999990337535948 GO:0019787 ubiquitin-like protein transferase activity 13/844 479/18639 0.0271398747390397 0.59936033798692 0.985231820576254 0.999990337535948 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/844 91/18639 0.010989010989011 0.24268267277746 0.985407844119138 0.999990337535948 GO:0052689 carboxylic ester hydrolase activity 1/844 92/18639 0.0108695652173913 0.240044817638574 0.986071839135498 0.999990337535948 GO:0140030 modification-dependent protein binding 3/844 173/18639 0.0173410404624277 0.382961674382927 0.986225953892593 0.999990337535948 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 5/844 243/18639 0.0205761316872428 0.454405827628576 0.986938754003757 0.999990337535948 GO:0004676 3-phosphoinositide-dependent protein kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0004711 ribosomal protein S6 kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0035175 histone H3S10 kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0035979 histone H2AXS139 kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0044022 histone H3S28 kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0044023 histone H4S1 kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0044024 histone H2AS1 kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0044025 histone H2BS14 kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0072354 histone H3T3 kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0072371 histone H2AS121 kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0072518 Rho-dependent protein serine/threonine kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0140823 histone H2BS36 kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0140855 histone H3S57 kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0140995 histone H2A kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0140997 histone H4 kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0140998 histone H2B kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:1990244 histone H2AT120 kinase activity 5/844 245/18639 0.0204081632653061 0.450696392300996 0.987746330447933 0.999990337535948 GO:0004677 DNA-dependent protein kinase activity 5/844 246/18639 0.0203252032520325 0.448864293145301 0.988132190807143 0.999990337535948 GO:0140857 histone H3T45 kinase activity 5/844 246/18639 0.0203252032520325 0.448864293145301 0.988132190807143 0.999990337535948 GO:0042393 histone binding 5/844 247/18639 0.0202429149797571 0.447047028800583 0.98850653700681 0.999990337535948 GO:0004679 AMP-activated protein kinase activity 5/844 248/18639 0.0201612903225806 0.445244419813484 0.988869687386684 0.999990337535948 GO:0004674 protein serine/threonine kinase activity 11/844 433/18639 0.0254041570438799 0.561028534527106 0.988884264368809 0.999990337535948 GO:0008170 N-methyltransferase activity 1/844 98/18639 0.0102040816326531 0.225348196150498 0.989467870036283 0.999990337535948 GO:0016755 aminoacyltransferase activity 13/844 496/18639 0.0262096774193548 0.578817745757529 0.990149731157784 0.999990337535948 GO:0022836 gated channel activity 7/844 318/18639 0.0220125786163522 0.486128498613968 0.990606866016292 0.999990337535948 GO:0004842 ubiquitin-protein transferase activity 11/844 449/18639 0.0244988864142539 0.54103642639251 0.992631398924066 0.999990337535948 GO:0004386 helicase activity 2/844 155/18639 0.0129032258064516 0.28495642868063 0.993798323580213 0.999990337535948 GO:0008514 organic anion transmembrane transporter activity 5/844 269/18639 0.0185873605947955 0.41048556176113 0.99439675392689 0.999990337535948 GO:0140097 catalytic activity, acting on DNA 7/844 336/18639 0.0208333333333333 0.460085900473934 0.994516351619893 0.999990337535948 GO:0046982 protein heterodimerization activity 8/844 369/18639 0.021680216802168 0.478788579354988 0.994688531574221 0.999990337535948 GO:0015294 solute:monoatomic cation symporter activity 1/844 116/18639 0.00862068965517241 0.190380372609904 0.99544863015269 0.999990337535948 GO:0008168 methyltransferase activity 3/844 204/18639 0.0147058823529412 0.3247665179816 0.995656450138932 0.999990337535948 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/844 167/18639 0.0119760479041916 0.26448051763771 0.996217406556862 0.999990337535948 GO:0004518 nuclease activity 3/844 209/18639 0.0143540669856459 0.316996984058595 0.996408557777253 0.999990337535948 GO:0008094 ATP-dependent activity, acting on DNA 3/844 210/18639 0.0142857142857143 0.315487474610697 0.996542982070302 0.999990337535948 GO:0061630 ubiquitin protein ligase activity 7/844 353/18639 0.0198300283286119 0.437928789119665 0.996747281891594 0.999990337535948 GO:0046873 metal ion transmembrane transporter activity 10/844 450/18639 0.0222222222222222 0.490758293838863 0.9968584013317 0.999990337535948 GO:0015291 secondary active transmembrane transporter activity 5/844 287/18639 0.0174216027874564 0.384740822695972 0.996940824798069 0.999990337535948 GO:0016741 transferase activity, transferring one-carbon groups 3/844 215/18639 0.013953488372093 0.308150556596495 0.997144958216977 0.999990337535948 GO:0015297 antiporter activity 1/844 135/18639 0.00740740740740741 0.163586097946288 0.998124437223763 0.999990337535948 GO:0061659 ubiquitin-like protein ligase activity 7/844 372/18639 0.0188172043010753 0.415561458492585 0.998212134498777 0.999990337535948 GO:0015081 sodium ion transmembrane transporter activity 1/844 164/18639 0.00609756097560976 0.13465928794359 0.999516158599292 0.999990337535948 GO:0140098 catalytic activity, acting on RNA 6/844 387/18639 0.0155038759689922 0.342389507329439 0.999664634518844 0.999990337535948 GO:0045182 translation regulator activity 3/844 356/18639 0.00842696629213483 0.186102161989456 0.999990337535948 0.999990337535948