category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	49/99	238/9376	19.4985145573381	RPS21/RPS27/RPL37/RPS28/RPL39/RPL34/RPL8/RPL35A/RPL30/RPL37A/RPS27A/RPL36/FAU/RPS23/RPS13/RPL11/RPL21/RPS29/RPS4X/RPL41/RPS15/RPS15A/RPL36AL/UBA52/RPS8/RPL35/RPL10/RPL3/RPL38/RPS12/RPL15/RPL12/RPL13/RPL23/RPL22/RPS7/RPL28/RPL18/RPS3/RPL10A/RPL27A/RPL32/RPL19/RPL7/RPL5/RPL18A/C7/RPL14/STAT1	29.8606470727821
Genetic Information Processing	Translation	hsa03010	Ribosome	47/99	222/9376	20.0505960505961	RPS21/RPS27/RPL37/RPS28/RPL39/RPL34/RPL8/RPL35A/RPL30/RPL37A/RPS27A/RPL36/FAU/RPS23/RPS13/RPL11/RPL21/RPS29/RPS4X/RPL41/RPS15/RPS15A/RPL36AL/UBA52/RPS8/RPL35/RPL10/RPL3/RPL38/RPS12/RPL15/RPL12/RPL13/RPL23/RPL22/RPS7/RPL28/RPL18/RPS3/RPL10A/RPL27A/RPL32/RPL19/RPL7/RPL5/RPL18A/RPL14	29.674202682692
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	10/99	138/9376	6.8628312106573	COX4I1/COX7C/MT-ND3/ATP6V1G1/UQCRB/ATP5F1E/COX6B1/NDUFB1/COX7A2/NDUFA4	7.16733019413005
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	10/99	205/9376	4.61985710766199	COX4I1/COX7C/MT-ND3/UQCRB/ATP5F1E/COX6B1/NDUFB1/COX7A2/CYBA/NDUFA4	5.41326724733749
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	11/99	268/9376	3.88723051409619	RPS27A/COX4I1/COX7C/MT-ND3/UBA52/UQCRB/ATP5F1E/COX6B1/NDUFB1/COX7A2/NDUFA4	4.95378098997461
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	10/99	227/9376	4.17211765229386	COX4I1/COX7C/MT-ND3/UQCRB/ATP5F1E/COX6B1/NDUFB1/COX7A2/CYBA/NDUFA4	4.99775380768237
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	11/99	275/9376	3.78828282828283	COX4I1/COX7C/MT-ND3/UQCRB/ATP5F1E/COX6B1/NDUFB1/COX7A2/CYBA/C7/NDUFA4	4.84794931954134
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	14/99	480/9376	2.76228956228956	RPS27A/COX4I1/COX7C/MT-ND3/UBA52/UQCRB/ATP5F1E/COX6B1/NDUFB1/DKK1/RAB1A/COX7A2/NDUFA4/GPX1	4.09449134804809
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	9/99	235/9376	3.62707930367505	COX4I1/COX7C/MT-ND3/UQCRB/ATP5F1E/COX6B1/NDUFB1/COX7A2/NDUFA4	4.21317711857802
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	7/99	157/9376	4.22260824808595	COX4I1/COX7C/UQCRB/COX6B1/NDUFB1/COX7A2/NDUFA4	4.20644185618552
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	10/99	308/9376	3.07490489308671	COX4I1/COX7C/MT-ND3/UQCRB/ATP5F1E/COX6B1/NDUFB1/COX7A2/NDUFA4/GPX1	3.82487507000407
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	11/99	368/9376	2.83091787439613	COX4I1/COX7C/MT-ND3/UQCRB/ATP5F1E/COX6B1/NDUFB1/RAB1A/COX7A2/NDUFA4/GPX1	3.70150245953925
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	5/99	87/9376	5.44293509810751	COX4I1/COX7C/UQCRB/COX6B1/COX7A2	4.30075369594683
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	10/99	388/9376	2.44090388420285	COX4I1/COX7C/MT-ND3/UQCRB/ATP5F1E/COX6B1/NDUFB1/DKK1/COX7A2/NDUFA4	2.994461958497
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	3/99	78/9376	3.64257964257964	HLA-DQA2/CYBA/STAT1	2.42091796177318
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	4/99	143/9376	2.64914883096701	HLA-DQA2/H3-3A/H3-3B/C7	2.05284381915734
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	2/99	44/9376	4.3048668503214	RAB11A/ARHGDIB	2.2698251161787
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	4/99	155/9376	2.44405343760182	HLA-DQA2/ATP6V1G1/CTSS/CYBA	1.87266269899853
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	3/99	99/9376	2.8699112335476	HLA-DQA2/KRT24/KRT10	1.93212075987708
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	3/99	105/9376	2.70591630591631	RPS27A/TOMM7/UBA52	1.81588581706284
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	4/99	196/9376	1.93279736136879	RPS27A/UBA52/CLEC2B/STAT1	1.3633063613728
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	2/99	66/9376	2.8699112335476	HLA-DQA2/STAT1	1.57477160424803
NA	NA	hsa04382	Cornified envelope formation	4/99	217/9376	1.74575245542987	KRT6A/KRT24/SPRR3/KRT10	1.14815358604273
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	3/99	149/9376	1.90685377262558	MT-ND3/NDUFB1/NDUFA4	1.15265568119012
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	2/99	82/9376	2.30992855383099	HLA-DQA2/CTSS	1.23070129708331
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/99	232/9376	1.63288052943225	TMSB4X/CYRIB/SSH2/C7	1.00831696843414
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	1/99	28/9376	3.38239538239538	ATP6V1G1	1.30416625774561
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/99	93/9376	2.03671119800152	HLA-DQA2/STAT1	1.03789769111049
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	3/99	169/9376	1.68119060426753	RPS27A/UBA52/RAB1A	0.923107728467111
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/99	95/9376	1.99383306751728	HLA-DQA2/ATP6V1G1	1.00572053171758
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	3/99	173/9376	1.64231914520932	HLA-DQA2/RAB11A/STAT1	0.880863601490859
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	4/99	253/9376	1.49734499141614	RPS27A/H3-3A/UBA52/H3-3B	0.828416287610594
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/99	31/9376	3.05506679700228	SRP14	1.18390428876385
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/99	100/9376	1.89414141414141	HLA-DQA2/CD37	0.928592769865785
Human Diseases	Immune disease	hsa05310	Asthma	1/99	32/9376	2.95959595959596	HLA-DQA2	1.14702944536745
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	3/99	180/9376	1.57845117845118	HLA-DQA2/SRSF5/STAT1	0.809474064663192
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	3/99	181/9376	1.56973045370835	HLA-DQA2/CTSS/STAT1	0.799525486267905
Genetic Information Processing	Transcription	hsa03020	RNA polymerase	1/99	34/9376	2.78550207961973	POLR1F	1.07740588795454
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/99	109/9376	1.7377444166435	HLA-DQA2/STAT1	0.80029306968424
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	2/99	112/9376	1.69119769119769	HLA-DQA2/STAT1	0.760171309110373
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	3/99	195/9376	1.45703185703186	H3-3A/H3-3B/CYBA	0.66622088410932
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/99	39/9376	2.42838642838643	HLA-DQA2	0.923365824504619
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/99	42/9376	2.25493025493025	FTH1	0.841995545465761
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/99	44/9376	2.1524334251607	HLA-DQA2	0.791506118589682
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/99	45/9376	2.10460157126824	HLA-DQA2	0.767268336244616
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/99	46/9376	2.05884936319719	FTH1	0.743655391515344
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/99	133/9376	1.42416647679806	CD48/CD244	0.508926591062062
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/99	50/9376	1.89414141414141	HLA-DQA2	0.654851707814938
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/99	51/9376	1.85700138641315	CHPT1	0.633930503256485
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/99	51/9376	1.85700138641315	ATP6V1G1	0.633930503256485
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/99	53/9376	1.78692586239756	RAB11A	0.593462618641731
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	2/99	139/9376	1.36269166484994	KRT24/KRT10	0.445019417086017
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/99	54/9376	1.75383464272353	HLA-DQA2	0.573875758164194
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/99	142/9376	1.33390240432494	RPS27A/UBA52	0.414160084484812
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	2/99	142/9376	1.33390240432494	CYBA/STAT1	0.414160084484812
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/99	56/9376	1.69119769119769	RAB1A	0.535904980618831
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/99	59/9376	1.60520458825544	GPX1	0.481714397998855
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/99	61/9376	1.55257492962411	FTH1	0.44726418398293
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/99	160/9376	1.18383838383838	HLA-DQA2/SELL	0.242283818030134
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/99	70/9376	1.35295815295815	HLA-DQA2	0.306189413717311
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/99	71/9376	1.33390240432494	STAT1	0.291735976536855
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/99	71/9376	1.33390240432494	ATP6V1G1	0.291735976536855
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	2/99	168/9376	1.12746512746513	FTH1/STAT1	0.172211768770119
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/99	75/9376	1.26276094276094	GPX1	0.236007648698831
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/99	77/9376	1.22996195723468	STAT1	0.209306488779593
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/99	78/9376	1.21419321419321	INPP5A	0.196226517140686
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/99	78/9376	1.21419321419321	BTG1	0.196226517140686
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/99	79/9376	1.19882367983634	ATP6V1G1	0.18331993510812
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/99	83/9376	1.1410490446635	L3MBTL4	0.133330861053644
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/99	187/9376	1.01290984713445	CYBA/STAT1	0.0184207468620375
Human Diseases	Substance dependence	hsa05034	Alcoholism	2/99	191/9376	0.991697075466709	H3-3A/H3-3B	-0.0119758859398087
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	2/99	193/9376	0.98142042183493	CXCL14/STAT1	-0.0269414936149795
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/99	88/9376	1.07621671258035	C7	0.0742044418104362
NA	NA	hsa04517	IgSF CAM signaling	3/99	299/9376	0.950238167629472	CD48/CD244/CD96	-0.0903358733436334
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/99	90/9376	1.05230078563412	STAT1	0.0515008722890698
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	2/99	200/9376	0.947070707070707	RPS3/RAB1A	-0.0781598729881766
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/99	201/9376	0.942358912508166	H3-3A/H3-3B	-0.0853348865280129
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	2/99	204/9376	0.928500693206576	LUM/DCN	-0.106655768441964
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	2/99	205/9376	0.923971421532397	HLA-DQA2/STAT1	-0.113695928165
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/99	98/9376	0.966398680684395	INPP5A	-0.0345415355845974
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/99	99/9376	0.956637077849199	CHPT1	-0.0448055504418485
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/99	100/9376	0.947070707070707	CXCL14	-0.0549686637381012
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	2/99	212/9376	0.89346293119878	SIPA1L1/SIPA1L3	-0.162078568055366
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	1/99	101/9376	0.937693769376938	STAT1	-0.0650331309613323
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/99	102/9376	0.928500693206576	RAB11A	-0.0750011337645336
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/99	104/9376	0.910644910644911	CHPT1	-0.0946561222371131
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/99	105/9376	0.901972101972102	STAT1	-0.104347129509222
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/99	109/9376	0.86887220832175	STAT1	-0.142245282452355
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/99	110/9376	0.860973370064279	DCN	-0.151512214978555
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/99	115/9376	0.823539745278876	NACA	-0.19668277950375
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/99	116/9376	0.816440264716127	CYBA	-0.20549458450092
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/99	120/9376	0.789225589225589	ARHGDIB	-0.24004700465625
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/99	122/9376	0.776287464812055	STAT1	-0.256924159449763
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/99	122/9376	0.776287464812055	STAT1	-0.256924159449763
Genetic Information Processing	Transcription	hsa03040	Spliceosome	2/99	243/9376	0.779482063432681	SRSF5/SNRPB2	-0.359782292887024
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/99	250/9376	0.757656565656566	ATP6V1G1/CTSS	-0.401199596414623
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/99	136/9376	0.696375519904932	STAT1	-0.368442491062625
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/99	137/9376	0.691292486912925	CTSS	-0.376005724037204
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/99	138/9376	0.68628312106573	INPP5A	-0.383519903269013
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	1/99	142/9376	0.66695120216247	CYBA	-0.413101302845738
NA	NA	hsa04519	Cadherin signaling	3/99	404/9376	0.703270327032703	KRT6A/KRT24/KRT10	-0.629805552625113
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/99	156/9376	0.607096607096607	STAT1	-0.511189676937833
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/99	158/9376	0.599411839918169	ATP6V1G1	-0.524575203495891
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/99	163/9376	0.581024973663011	STAT1	-0.557417835743406
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/99	168/9376	0.563732563732564	STAT1	-0.589419148205652
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/99	174/9376	0.544293509810751	SSR4	-0.626784402800775
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/99	178/9376	0.532062194983543	DKK1	-0.651104788425494
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/99	184/9376	0.514712340799297	SSH2	-0.6867562306329
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	2/99	333/9376	0.568811235477902	ATP6V1G1/STAT1	-0.827623367914466
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/99	216/9376	0.438458660680883	CYBA	-0.86250243418468
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	1/99	224/9376	0.422799422799423	HLA-DQA2	-0.903217237594197
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	1/99	233/9376	0.406468114622621	DCN	-0.947713599403087
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/99	248/9376	0.381883349625285	RPS3	-1.01907916923236
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/99	250/9376	0.378828282828283	RAB11A	-1.02834988250724
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/99	298/9376	0.317808962104264	CXCL14	-1.23628474319648