category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Immune disease	hsa05330	Allograft rejection	9/148	39/9376	14.6195426195426	HLA-DRB5/HLA-DRA/HLA-DQA2/HLA-DPB1/HLA-DQA1/HLA-DRB1/HLA-C/HLA-DMA/GZMB	10.7932901009622
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	11/148	70/9376	9.95521235521236	HLA-DRB5/ITGB2/HLA-DRA/HLA-DQA2/HLA-DPB1/HLA-DQA1/LAMA2/HLA-DRB1/HLA-C/HLA-DMA/FYN	9.52370835744566
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	9/148	44/9376	12.958230958231	HLA-DRB5/HLA-DRA/HLA-DQA2/HLA-DPB1/HLA-DQA1/HLA-DRB1/HLA-C/HLA-DMA/GZMB	10.068588996847
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	9/148	45/9376	12.6702702702703	HLA-DRB5/HLA-DRA/HLA-DQA2/HLA-DPB1/HLA-DQA1/HLA-DRB1/HLA-C/HLA-DMA/GZMB	9.93769764272894
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	9/148	50/9376	11.4032432432432	HLA-DRB5/HLA-DRA/HLA-DQA2/CXCR4/HLA-DPB1/HLA-DQA1/HLA-DRB1/HLA-DMA/CCR9	9.34047048901687
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	9/148	54/9376	10.5585585585586	HLA-DRB5/HLA-DRA/HLA-DQA2/HLA-DPB1/HLA-DQA1/HLA-DRB1/HLA-C/HLA-DMA/GZMB	8.92066927647318
Human Diseases	Immune disease	hsa05310	Asthma	7/148	32/9376	13.8581081081081	HLA-DRB5/HLA-DRA/HLA-DQA2/HLA-DPB1/HLA-DQA1/HLA-DRB1/HLA-DMA	9.2267414303827
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	10/148	82/9376	7.72577455504285	HLA-DRB5/HLA-DRA/HLA-DQA2/CD74/HLA-DPB1/HLA-DQA1/PSME2/HLA-DRB1/HLA-C/HLA-DMA	7.74659053648335
NA	NA	hsa04518	Integrin signaling	13/148	154/9376	5.34784134784135	COL1A1/IGF1/ITGB2/PDGFRA/COL6A1/PIK3R1/FN1/COL6A3/LAMA2/LAMA4/COL4A1/FLNA/COL4A2	6.88944429229662
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	13/148	155/9376	5.31333914559721	HLA-DRB5/ITGB2/HLA-DRA/HLA-DQA2/HLA-DPB1/SEC61B/HLA-DQA1/C1R/HLA-DRB1/SEC61G/HLA-C/TUBA4A/HLA-DMA	6.85729996916008
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	14/148	203/9376	4.3690587138863	COL1A1/IGF1/PDGFRA/COL6A1/PPP1CB/PIK3R1/FN1/COL6A3/LAMA2/LAMA4/COL4A1/FYN/FLNA/COL4A2	6.14559030700305
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	13/148	180/9376	4.57537537537537	HLA-DRB5/BAX/HLA-DRA/HLA-DQA2/BST2/CD74/PPP1CB/HLA-DPB1/PIK3R1/HLA-DQA1/HLA-DRB1/HLA-C/HLA-DMA	6.1336800601609
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	8/148	66/9376	7.67895167895168	HLA-DRB5/HLA-DRA/HLA-DQA2/HLA-DPB1/HLA-DQA1/HLA-DRB1/HLA-DMA/IL21R	6.89553761191315
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	9/148	89/9376	6.40631642878834	COL1A1/CD44/COL6A1/FN1/COL6A3/LAMA2/LAMA4/COL4A1/COL4A2	6.48965253434549
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	9/148	95/9376	6.00170697012802	HLA-DRB5/ITGB2/HLA-DRA/HLA-DQA2/HLA-DPB1/CCL3/HLA-DQA1/HLA-DRB1/HLA-DMA	6.20505112133521
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	14/148	233/9376	3.80651896531725	COL3A1/COL1A1/EMD/ATP1B3/COL6A1/FN1/COL6A3/DCN/LAMA2/ELN/NID1/COL4A1/FBLN1/COL4A2	5.49369171668318
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	9/148	99/9376	5.75921375921376	HLA-DRB5/ITGB2/HLA-DRA/HLA-DQA2/HLA-DPB1/HLA-DQA1/C1R/HLA-DRB1/HLA-DMA	6.0285342617772
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	9/148	100/9376	5.70162162162162	HLA-DRB5/HLA-DRA/CD44/HLA-DQA2/HLA-DPB1/MME/HLA-DQA1/HLA-DRB1/HLA-DMA	5.98590758953719
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	8/148	78/9376	6.4975744975745	HLA-DRB5/ITGB2/HLA-DRA/HLA-DQA2/HLA-DPB1/HLA-DQA1/HLA-DRB1/HLA-DMA	6.17428051170373
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	9/148	103/9376	5.53555497244818	COL3A1/COL1A1/ATP1B3/COL6A1/MME/COL6A3/ELN/COL4A1/COL4A2	5.86140351652627
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	9/148	103/9376	5.53555497244818	COL3A1/COL1A1/ITGB2/PIK3R1/FN1/LAMA2/LAMA4/COL4A1/COL4A2	5.86140351652627
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	13/148	224/9376	3.67664092664093	HLA-DRB5/ITGB2/BAX/HLA-DRA/HLA-DQA2/HLA-DPB1/PIK3R1/HLA-DQA1/HLA-DRB1/ZFP36/HLA-C/NRP1/HLA-DMA	5.13474428946798
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	9/148	109/9376	5.23084552442351	HLA-DRB5/HLA-DRA/HLA-DQA2/IRF4/HLA-DPB1/HLA-DQA1/HLA-DRB1/HLA-DMA/IL21R	5.62643802119034
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	9/148	112/9376	5.09073359073359	HLA-DRB5/HLA-DRA/HLA-DQA2/HLA-DPB1/HLA-DQA1/LAMA2/LAMA4/HLA-DRB1/HLA-DMA	5.51535711718211
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	11/148	173/9376	4.02812060615529	HLA-DRB5/BAX/HLA-DRA/HLA-DQA2/HLA-DPB1/PIK3R1/HLA-DQA1/HLA-DRB1/MX1/HLA-DMA/PABPN1	5.09089584759575
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	12/148	205/9376	3.70837178642057	HLA-DRB5/BAX/ISG15/HLA-DRA/CD44/HLA-DQA2/HLA-DPB1/PIK3R1/HLA-DQA1/HLA-DRB1/HLA-C/HLA-DMA	4.96523225302358
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	11/148	181/9376	3.85008212632522	HLA-DRB5/ITGB2/BAX/HLA-DRA/HLA-DQA2/CD74/HLA-DPB1/HLA-DQA1/HLA-DRB1/HLA-DMA/CTSD	4.90324391668174
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	15/148	333/9376	2.8536644752861	COL1A1/BAX/ISG15/PPP2R2B/COL6A1/PIK3R1/FN1/COL6A3/LAMA2/LAMA4/BCAP31/MX1/HLA-C/COL4A1/COL4A2	4.36173906792546
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	11/148	204/9376	3.41600423953365	COL1A1/IGF1/CD44/CD63/PPP1CB/HPSE2/PIK3R1/TIMP3/FN1/DCN/FLNA	4.41818051183418
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	15/148	362/9376	2.62505599522174	COL1A1/IGF1/PPP2R2B/PDGFRA/COL6A1/PIK3R1/HSP90B1/FN1/COL6A3/GNG2/LAMA2/LAMA4/COL4A1/MCL1/COL4A2	3.99325037951935
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	7/148	93/9376	4.76838128451032	HLA-DRB5/HLA-DRA/HLA-DQA2/HLA-DPB1/HLA-DQA1/HLA-DRB1/HLA-DMA	4.62503304721483
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	7/148	93/9376	4.76838128451032	BAX/PIK3R1/FN1/LAMA2/LAMA4/COL4A1/COL4A2	4.62503304721483
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	9/148	160/9376	3.56351351351351	HLA-DRB5/ITGB2/HLA-DRA/HLA-DQA2/HLA-DPB1/HLA-DQA1/HLA-DRB1/HLA-C/HLA-DMA	4.14178043660624
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	7/148	101/9376	4.39068771742039	COL3A1/COL1A1/BAX/PIK3R1/FN1/COL4A1/COL4A2	4.33864607280967
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	4/148	31/9376	8.1743679163034	SPCS2/SEC61B/SEC61G/SRP14	5.06684409554543
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	10/148	205/9376	3.09030982201714	COL3A1/COL1A1/PPP1CB/UQCRB/PIK3R1/NDUFB2/COX6C/RYR2/NDUFS6/CTSD	3.83214512834975
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	8/148	143/9376	3.54413154413154	HLA-DRB5/HLA-DRA/HLA-DQA2/HLA-DPB1/HLA-DQA1/C1R/HLA-DRB1/HLA-DMA	3.88238738039296
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	11/148	250/9376	2.78745945945946	BIN1/ARF5/PDGFRA/ARPC3/CXCR4/CBLB/WIPF3/CYTH1/VPS37B/DAB2/HLA-C	3.62767753554349
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	10/148	227/9376	2.79080842957495	BAX/CCL4/PDGFRA/CXCR4/PIK3R1/GNA13/CCL3/GNG2/HLA-C/AKAP13	3.45889953352432
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	4/148	46/9376	5.50881316098707	PSMA7/PSME2/PSME4/PSMB9	3.88206708505345
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	7/148	137/9376	3.23693036101795	BAX/CTSW/PIK3R1/TUBA4A/CTSD/MCL1/GZMB	3.34012689984599
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	7/148	149/9376	2.97623798294939	PDGFRA/PIK3R1/GNA13/PLPP3/CYTH1/DGKB/FYN	3.07939087825593
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	9/148	232/9376	2.45759552656104	ITGB2/PDGFRA/ARPC3/CXCR4/PPP1CB/PIK3R1/GNA13/FN1/TMSB4X	2.8469222948404
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	10/148	275/9376	2.3036855036855	BAX/UQCRB/PIK3R1/PSMA7/NDUFB2/COX6C/TUBA4A/RYR2/FYN/NDUFS6	2.77880024904608
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	8/148	200/9376	2.53405405405405	BAX/ARPC3/WIPF3/GNA13/MYO5B/CYTH1/TUBA4A/FYN	2.77710091203432
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	6/148	125/9376	3.04086486486487	BAX/PPP2R2B/PIK3R1/GNA13/FYN/CTSD	2.90895911948594
Organismal Systems	Immune system	hsa04611	Platelet activation	6/148	126/9376	3.01673101673102	COL3A1/COL1A1/PPP1CB/PIK3R1/GNA13/FYN	2.88619112450295
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	6/148	130/9376	2.92390852390852	COL3A1/COL1A1/PIK3R1/GNG2/COL4A1/COL4A2	2.79731808664801
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	5/148	99/9376	3.1995631995632	PDGFRA/PIK3R1/PLPP3/DGKB/SLC22A3	2.78620435651574
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	5/148	100/9376	3.16756756756757	CCL4/XCL2/CXCR4/CCL3/CCR9	2.75965617774708
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	3/148	38/9376	5.00142247510669	IGF1/ATP1B3/PIK3R1	3.12998296307896
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	9/148	268/9376	2.12747075433643	BAX/UBC/UQCRB/PSMA7/NDUFB2/COX6C/SNCAIP/TUBA4A/NDUFS6	2.37150407077019
Human Diseases	Cancer: specific types	hsa05218	Melanoma	4/148	73/9376	3.47130692336172	IGF1/BAX/PDGFRA/PIK3R1	2.68435103569761
Human Diseases	Cancer: specific types	hsa05214	Glioma	4/148	76/9376	3.33428165007112	IGF1/BAX/PDGFRA/PIK3R1	2.58750549563582
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	7/148	193/9376	2.2977174065257	CCL4/XCL2/CXCR4/PIK3R1/CCL3/GNG2/CCR9	2.3069022640456
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	4/148	80/9376	3.16756756756757	IGF1/BAX/PDGFRA/PIK3R1	2.46565485303567
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	6/148	157/9376	2.42107075228094	BAX/UQCRB/PIK3R1/NDUFB2/COX6C/NDUFS6	2.27397833562049
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	3/148	50/9376	3.80108108108108	ITGB2/GYPC/CD81	2.51492871630913
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	4/148	87/9376	2.91270580925753	ATP1B3/UQCRB/COX6C/RYR2	2.26979181061172
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	7/148	214/9376	2.07224046476383	BAX/BST2/AP1S1/CXCR4/PIK3R1/GNG2/HLA-C	2.00940111428367
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	6/148	174/9376	2.18452935694315	BAX/HSP90B1/SEC61B/PDIA6/BCAP31/SEC61G	1.99729420179432
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	5/148	133/9376	2.3816297500508	ITGB2/PIK3R1/HLA-C/FYN/GZMB	2.03223404720285
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	5/148	138/9376	2.29533881707795	UQCRB/NDUFB2/COX6C/ATP5MG/NDUFS6	1.94131784786812
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	4/148	98/9376	2.5857694429123	BIN1/ARPC3/PIK3R1/PLPP3	1.99842844027491
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	6/148	184/9376	2.06580493537015	CXCR4/PIK3R1/SLIT3/NRP1/SEMA5A/FYN	1.84903160121751
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	4/148	99/9376	2.55965055965056	IGF1/PPP1CB/PIK3R1/PRKCH	1.97562188020038
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	4/148	99/9376	2.55965055965056	IGF1/EMD/LAMA2/RYR2	1.97562188020038
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	12/148	480/9376	1.58378378378378	BAX/UBC/UQCRB/PSMA7/ATXN1/NDUFB2/COX6C/SNCAIP/TUBA4A/RYR2/NDUFS6/DKK1	1.66279213499102
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	4/148	105/9376	2.41338481338481	IGF1/EMD/LAMA2/RYR2	1.844397320193
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	4/148	106/9376	2.39061703212647	IGF1/PDGFRA/PIK3R1/HSP90B1	1.82340571985286
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	10/148	388/9376	1.63276678740596	MME/UQCRB/PIK3R1/PSMA7/NDUFB2/COX6C/TUBA4A/APOE/NDUFS6/DKK1	1.61209529246805
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	6/148	196/9376	1.93932708218423	BAX/UBC/PIK3R1/GNG2/ZFP36/HLA-C	1.68300823857731
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	3/148	68/9376	2.79491255961844	PIK3R1/ZBTB16/RUNX1T1	1.88118829782857
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	3/148	69/9376	2.75440658049354	PIK3R1/ALOX5AP/FYN	1.85230559706556
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	6/148	201/9376	1.89108511496571	IGF1/BAX/ZBTB16/RUNX1T1/WT1/GZMB	1.61724897412312
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	5/148	156/9376	2.03049203049203	BAX/PPP2R2B/PIK3R1/CD81/MX1	1.64363045234927
NA	NA	hsa04517	IgSF CAM signaling	8/148	299/9376	1.69501943414987	ITGB2/ARPC3/PIK3R1/SLIT3/NRP1/TUBA4A/FYN/PPFIA2	1.54676407959552
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	7/148	253/9376	1.7528041875868	BAX/CD44/UBC/ARPC3/FNBP1/PIK3R1/CYTH1	1.53722044657505
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	3/148	73/9376	2.60348019252129	BST2/CXCR4/MX1	1.74171151095226
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	3/148	73/9376	2.60348019252129	BAX/EML4/PIK3R1	1.74171151095226
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	4/148	115/9376	2.20352526439483	JUND/GNA13/PDE4D/AKAP13	1.64451520192551
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	2/148	36/9376	3.51951951951952	B4GALT5/GALNT11	1.91804257296949
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	8/148	308/9376	1.64548964548965	BAX/UQCRB/PSMA7/NDUFB2/COX6C/POLR2J3/TUBA4A/NDUFS6	1.458718817824
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	3/148	75/9376	2.53405405405405	BAX/PIK3R1/REV3L	1.68915372478268
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	3/148	76/9376	2.50071123755334	UBC/DBI/FABP5	1.66350901760865
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	3/148	78/9376	2.43659043659044	ARPC3/PIK3R1/FN1	1.61342285399746
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	3/148	78/9376	2.43659043659044	ITGB2/C1R/SERPING1	1.61342285399746
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	4/148	122/9376	2.07709348692955	IGF1/PPP2R2B/PIK3R1/PFKFB3	1.516461086563
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	4/148	122/9376	2.07709348692955	PPP2R2B/CBLB/PIK3R1/FYN	1.516461086563
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	5/148	169/9376	1.8743003358388	UBC/GABARAPL1/PIK3R1/HMGB1/CTSD	1.45247153136023
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	3/148	86/9376	2.20993086109365	EMD/LAMA2/RYR2	1.4274622298681
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	4/148	134/9376	1.89108511496571	PPP1CB/GNA13/PRKCH/CALCRL	1.31568313929434
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	3/148	88/9376	2.15970515970516	ITGB2/C1R/SERPING1	1.38417348302679
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	3/148	89/9376	2.13543880959611	GABARAPL1/GNG2/PLCL1	1.36296190675267
Human Diseases	Infectious disease: viral	hsa05162	Measles	4/148	136/9376	1.86327503974563	BAX/CBLB/PIK3R1/MX1	1.28423752494979
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	3/148	90/9376	2.11171171171171	IGF1/BAX/PIK3R1	1.34202868574339
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	3/148	91/9376	2.08850608850609	IFITM1/PIK3R1/CD81	1.32136654728703
Human Diseases	Substance dependence	hsa05032	Morphine addiction	3/148	91/9376	2.08850608850609	PDE4D/PDE7A/GNG2	1.32136654728703
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	4/148	138/9376	1.83627105366236	ARPC3/PIK3R1/WIPF3/FN1	1.25331527220999
NA	NA	hsa03272	Virion - Hepatitis viruses	2/148	48/9376	2.63963963963964	CD63/CD81	1.44223975346015
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	2/148	48/9376	2.63963963963964	ATP1B3/PIK3R1	1.44223975346015
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	4/148	142/9376	1.78454510848877	FOSL2/JUND/PIK3R1/FYN	1.19297092457125
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	2/148	51/9376	2.48436671966084	PLAAT2/PLPP3	1.34606049790794
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	2/148	51/9376	2.48436671966084	SEC61B/SEC61G	1.34606049790794
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	6/148	248/9376	1.53269398430689	BAX/ARPC3/HSP90B1/CYTH1/TUBA4A/FLNA	1.07665985509393
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	3/148	99/9376	1.91973791973792	IGF1/BAX/PIK3R1	1.16503940388501
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	2/148	55/9376	2.3036855036855	B4GALT5/PLPP3	1.22796398669737
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	3/148	103/9376	1.84518499081606	PPP2R2B/PPP1CB/PABPN1	1.09225228387221
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/148	103/9376	1.84518499081606	PPP2R2B/PIK3R1/CCL3	1.09225228387221
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	4/148	154/9376	1.64548964548965	PPP2R2B/ATP1B3/PPP1CB/RYR2	1.02282134928017
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	3/148	104/9376	1.82744282744283	PLAAT2/PLPP3/DGKB	1.07455996714761
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	4/148	157/9376	1.6140471681873	PPP1CB/PIK3R1/ZFP36L2/HLA-C	0.982590033090042
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	4/148	157/9376	1.6140471681873	ITGB2/PPP2R2B/PPP1CB/SNAI2	0.982590033090042
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/148	59/9376	2.14750343563903	PLAAT2/PIK3R1	1.1197076762049
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	2/148	59/9376	2.14750343563903	BAX/PIK3R1	1.1197076762049
Organismal Systems	Nervous system	hsa04730	Long-term depression	2/148	60/9376	2.11171171171171	IGF1/GNA13	1.09399608832536
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	3/148	109/9376	1.74361517480784	CCL4/PIK3R1/CCL3	0.988905094388433
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	3/148	110/9376	1.72776412776413	IGF1/PIK3R1/PFKFB3	0.972307291421795
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	5/148	216/9376	1.46646646646647	BAX/ABCG1/PIK3R1/HSP90B1/CCL3	0.87833920923998
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	2/148	62/9376	2.04359197907585	IGF1/PIK3R1	1.04404967718041
NA	NA	hsa04382	Cornified envelope formation	5/148	217/9376	1.45970855648275	PPP2R2B/KRT86/COL4A1/KRT81/COL4A2	0.867663099023262
Metabolism	Glycan biosynthesis and metabolism	hsa00531	Glycosaminoglycan degradation	1/148	19/9376	3.33428165007112	HPSE2	1.28980615401819
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	2/148	63/9376	2.01115401115401	PLAAT2/PTGDS	1.01977763995832
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	3/148	115/9376	1.65264394829612	PIK3R1/GNG2/FYN	0.891782604129493
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	2/148	65/9376	1.94927234927235	PLPP3/DGKB	0.972550247589345
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	4/148	168/9376	1.50836550836551	PDGFRA/PIK3R1/IL21R/MCL1	0.841997428896803
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	3/148	116/9376	1.63839701770736	ITGB2/CXCR4/PIK3R1	0.876147152382942
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/148	21/9376	3.01673101673102	CHSY3	1.17165144395202
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	5/148	226/9376	1.40157856972016	ATP1B3/PPP1CB/PIK3R1/PDE4D/RYR2	0.773885846723195
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	5/148	227/9376	1.39540421478747	UQCRB/PIK3R1/NDUFB2/COX6C/NDUFS6	0.763712874864322
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	1/148	23/9376	2.75440658049354	MME	1.06679605609243
Organismal Systems	Excretory system	hsa04964	Proximal tubule bicarbonate reclamation	1/148	23/9376	2.75440658049354	ATP1B3	1.06679605609243
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	2/148	71/9376	1.78454510848877	PDGFRA/PIK3R1	0.840333365521688
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	4/148	178/9376	1.42362587306408	APCDD1/PRICKLE1/SFRP4/DKK1	0.722617505846193
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	5/148	235/9376	1.34790109258194	UQCRB/NDUFB2/COX6C/ATP5MG/NDUFS6	0.683999166160634
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	5/148	238/9376	1.33091074267545	IGF1/PLAAT2/PDGFRA/PIK3R1/GNG2	0.654841916630503
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	5/148	238/9376	1.33091074267545	ISG15/PIK3R1/C1R/MX1/NRP1	0.654841916630503
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	3/148	128/9376	1.4847972972973	PDE4D/PDE7A/PDE9A	0.699365117865982
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	6/148	298/9376	1.27553056412117	CCL4/XCL2/CXCR4/CCL3/CCR9/IL21R	0.612132625511914
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/148	75/9376	1.68936936936937	IGF1/BAX	0.759067671014626
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	2/148	75/9376	1.68936936936937	ATP1B3/HSP90B1	0.759067671014626
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	6/148	300/9376	1.26702702702703	IGF1/PDGFRA/JUND/DUSP4/DUSP2/FLNA	0.595293728530343
Metabolism	Lipid metabolism	hsa00592	alpha-Linolenic acid metabolism	1/148	26/9376	2.43659043659044	PLAAT2	0.928916212023692
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	2/148	77/9376	1.64548964548965	BAX/PIK3R1	0.720243291238273
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	2/148	77/9376	1.64548964548965	BAX/PIK3R1	0.720243291238273
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	3/148	133/9376	1.42897785003048	IGF1/GABARAPL1/PIK3R1	0.630981919936052
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	3/148	133/9376	1.42897785003048	PPP2R2B/PPP1CB/GNG2	0.630981919936052
Metabolism	Glycan biosynthesis and metabolism	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/148	28/9376	2.26254826254826	B3GNT5	0.847286633853201
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	5/148	250/9376	1.26702702702703	CTSW/CD63/AP1S1/LITAF/CTSD	0.541935618289126
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	7/148	368/9376	1.20505287896592	BAX/UQCRB/PSMA7/NDUFB2/COX6C/TUBA4A/NDUFS6	0.508204252490276
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	3/148	138/9376	1.37720329024677	PPP1CB/CBLB/PIK3R1	0.56531269655186
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/148	139/9376	1.36729535290686	PIK3R1/HSP90B1/CTSD	0.552484457421444
Metabolism	Lipid metabolism	hsa00591	Linoleic acid metabolism	1/148	30/9376	2.11171171171171	PLAAT2	0.772329498887232
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	3/148	140/9376	1.35752895752896	GNA13/GNG2/RYR2	0.539754138960185
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	2/148	86/9376	1.4732872407291	CBLB/PIK3R1	0.558378731995157
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	2/148	86/9376	1.4732872407291	ATP1B3/RYR2	0.558378731995157
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	3/148	144/9376	1.31981981981982	PIK3R1/PSMA7/ATXN1	0.489780426857392
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	1/148	32/9376	1.97972972972973	GABARAPL1	0.703035999687594
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/148	32/9376	1.97972972972973	BAX	0.703035999687594
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/148	87/9376	1.45635290462877	BAX/PIK3R1	0.541550133147412
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	6/148	323/9376	1.1768052882604	CD44/PDGFRA/ZEB2/PIK3R1/TIMP3/MCL1	0.409508532007597
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	2/148	89/9376	1.42362587306408	PDGFRA/TUBA4A	0.508513468820534
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	3/148	148/9376	1.28414901387874	IGF1/BAX/PIK3R1	0.441251221802823
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/148	90/9376	1.40780780780781	EML4/PIK3R1	0.492294693473669
Genetic Information Processing	Transcription	hsa03020	RNA polymerase	1/148	34/9376	1.86327503974563	POLR2J3	0.638603676026256
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	3/148	149/9376	1.27553056412117	NDUFB2/GNG2/NDUFS6	0.429334074719666
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	1/148	35/9376	1.81003861003861	PFKFB3	0.60800305140246
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	4/148	212/9376	1.19530851606323	IGF1/ITGB2/PDGFRA/PIK3R1	0.364258146576944
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	2/148	93/9376	1.36239465271723	FYN/SNAI2	0.444776448667917
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/148	94/9376	1.34790109258194	JUND/HSP90B1	0.429300743255102
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/148	37/9376	1.71219868517166	LAMA4	0.549685833999454
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/148	37/9376	1.71219868517166	BAX	0.549685833999454
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/148	38/9376	1.66714082503556	NAMPT	0.521849274683268
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/148	97/9376	1.30621342992477	GNG2/RYR2	0.383903628433041
NA	NA	hsa04519	Cadherin signaling	7/148	404/9376	1.0976719293551	PDGFRA/ARPC3/PPP1CB/LHFPL3/KRT86/KRT81/PRICKLE1	0.25414321504835
NA	NA	hsa04081	Hormone signaling	4/148	219/9376	1.15710230778724	IGF1/PIK3R1/GNA13/GNG2	0.297913866485893
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	2/148	98/9376	1.29288472145615	PIK3R1/DGKB	0.36910104409947
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	2/148	102/9376	1.24218335983042	ATP1B3/RYR2	0.311439392077987
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/148	42/9376	1.50836550836551	PCBP2	0.418147521310079
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	3/148	166/9376	1.14490394008466	ATP1B3/PPP1CB/GNA13	0.238543246972562
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	2/148	105/9376	1.20669240669241	UBC/GABARAPL1	0.26972337426971
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	2/148	105/9376	1.20669240669241	CBLB/PIK3R1	0.26972337426971
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/148	43/9376	1.4732872407291	PLPP3	0.393922778393187
Genetic Information Processing	Replication and repair	hsa03410	Base excision repair	1/148	44/9376	1.43980343980344	HMGB1	0.370305615458313
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/148	170/9376	1.11796502384738	PPP2R2B/ARPC3/TUBA4A	0.196564433113505
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/148	45/9376	1.40780780780781	ABCG1	0.347264510288351
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	2/148	109/9376	1.16241011653856	PPP1CB/PIK3R1	0.215982939921448
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	2/148	110/9376	1.15184275184275	IGF1/PIK3R1	0.202864924408734
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/148	47/9376	1.34790109258194	PIK3R1	0.302795821729324
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	1/148	49/9376	1.29288472145615	GALNT11	0.260307374355334
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/148	52/9376	1.21829521829522	IGF1	0.199897547121105
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/148	52/9376	1.21829521829522	APOE	0.199897547121105
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	2/148	120/9376	1.05585585585586	BAX/PIK3R1	0.0779848720131403
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/148	53/9376	1.19530851606323	ATP1B3	0.180569325576084
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/148	122/9376	1.03854674346478	ATP1B3/PIK3R1	0.0542707176186677
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/148	122/9376	1.03854674346478	IGF1/PIK3R1	0.0542707176186677
Genetic Information Processing	Replication and repair	hsa03460	Fanconi anemia pathway	1/148	54/9376	1.17317317317317	REV3L	0.161616481812741
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/148	56/9376	1.13127413127413	ITGB2	0.124775096167297
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	3/148	195/9376	0.974636174636175	ITGB2/PIK3R1/HMGB1	-0.0453262478524654
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/148	60/9376	1.05585585585586	PIK3R1	0.0549657678088917
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/148	61/9376	1.03854674346478	ATP1B3	0.0382493345999899
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/148	62/9376	1.02179598953792	ATXN1	0.0218055488132918
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/148	205/9376	0.927092946605142	BAX/PIK3R1/HLA-C	-0.133659808008667
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/148	63/9376	1.00557700557701	POLR2J3	0.00562456907910825
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/148	63/9376	1.00557700557701	BAX	0.00562456907910825
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	2/148	138/9376	0.918135526831179	IGF1/PPP1CB	-0.122689879106271
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/148	65/9376	0.974636174636175	PIK3R1	-0.0259857928615638
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/148	67/9376	0.945542557482856	PPP1CB	-0.0566507717880401
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/148	142/9376	0.892272554244385	UBC/CBLB	-0.163809205072132
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/148	142/9376	0.892272554244385	PIK3R1/HSP90B1	-0.163809205072132
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/148	68/9376	0.931637519872814	ALDH1A3	-0.0716484471272175
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	2/148	144/9376	0.87987987987988	IGF1/PIK3R1	-0.18395508989949
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/148	69/9376	0.918135526831179	PPP1CB	-0.0864326567954237
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/148	70/9376	0.905019305019305	PIK3R1	-0.101010272308857
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/148	71/9376	0.892272554244385	PIK3R1	-0.115387842039126
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/148	72/9376	0.87987987987988	ISG15	-0.129571610893992
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	2/148	150/9376	0.844684684684685	BAX/PIK3R1	-0.242837576538564
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/148	76/9376	0.833570412517781	ATP1B3	-0.184483938445699
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/148	154/9376	0.822744822744823	PPP1CB/RYR2	-0.280872638056817
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/148	78/9376	0.812196812196812	CNOT6L	-0.210920209085051
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	2/148	157/9376	0.807023584093648	DUSP4/DUSP2	-0.308798269440408
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	2/148	158/9376	0.801915839890523	IGF1/PIK3R1	-0.317996721815796
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	2/148	163/9376	0.777317194495109	BAX/PIK3R1	-0.363197335513086
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/148	83/9376	0.763269293389775	CCL4	-0.274333203529816
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	2/148	168/9376	0.754182754182754	BAX/HMGB1	-0.407143060555163
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	2/148	170/9376	0.745310015898251	BAX/PIK3R1	-0.424388439148027
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/148	90/9376	0.703903903903904	ATP1B3	-0.357439298796052
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	3/148	254/9376	0.748244307299425	PDGFRA/CXCR4/RYR2	-0.515126422636438
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/148	93/9376	0.681197326358617	ATP1B3	-0.391274871041464
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/148	98/9376	0.646442360728075	ATP1B3	-0.44556265398825
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/148	187/9376	0.677554559907501	GABARAPL1/NAMPT	-0.564034436493806
Human Diseases	Substance dependence	hsa05034	Alcoholism	2/148	191/9376	0.663364935616245	PPP1CB/GNG2	-0.595249661350771
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/148	105/9376	0.603346203346203	CCL4	-0.517613598691934
Cellular Processes	Cell motility	hsa04814	Motor proteins	2/148	194/9376	0.653106714962385	MYO5B/TUBA4A	-0.618287998882826
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/148	110/9376	0.575921375921376	DCN	-0.566577442604328
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/148	115/9376	0.550881316098707	GNG2	-0.613682591462536
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/148	116/9376	0.546132339235788	GNG2	-0.62289585870145
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/148	119/9376	0.532364297070179	PIK3R1	-0.650142733595925
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	2/148	217/9376	0.5838834225931	PIK3R1/HSP90B1	-0.785386728213687
NA	NA	hsa04082	Neuroactive ligand signaling	1/148	199/9376	0.318348499253022	GNG2	-1.23083906181511
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	2/148	370/9376	0.342439737034332	GPR35/CALCRL	-1.63430516847608