ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 46/425 175/18639 0.262857142857143 11.5279865546218 7.49065753451215e-36 5.58803052074607e-33 GO:0031386 protein tag activity 6/425 15/18639 0.4 17.5425882352941 5.70422309731472e-07 0.000141845014353226 GO:0141047 molecular tag activity 6/425 15/18639 0.4 17.5425882352941 5.70422309731472e-07 0.000141845014353226 GO:0044389 ubiquitin-like protein ligase binding 23/425 322/18639 0.0714285714285714 3.13260504201681 1.50045418062234e-06 0.000279834704686067 GO:0019843 rRNA binding 10/425 65/18639 0.153846153846154 6.74714932126697 1.99680190007547e-06 0.00029792284349126 GO:0004857 enzyme inhibitor activity 25/425 416/18639 0.0600961538461538 2.63560520361991 1.13949173514182e-05 0.00141676805735967 GO:0042277 peptide binding 18/425 249/18639 0.072289156626506 3.1703472714387 1.76125470682234e-05 0.0018769943018421 GO:0031625 ubiquitin protein ligase binding 20/425 302/18639 0.0662251655629139 2.90440202571095 2.18882691862724e-05 0.0020410811016199 GO:0045296 cadherin binding 21/425 334/18639 0.062874251497006 2.75744276153575 2.96286951758151e-05 0.0024558896223509 GO:0003725 double-stranded RNA binding 9/425 75/18639 0.12 5.26277647058823 5.08032417824125e-05 0.00378992183696797 GO:0019838 growth factor binding 12/425 136/18639 0.0882352941176471 3.86968858131488 6.71238180352683e-05 0.00455221529584638 GO:1990948 ubiquitin ligase inhibitor activity 4/425 11/18639 0.363636363636364 15.947807486631 7.74543636749032e-05 0.00481507960845648 GO:0048020 CCR chemokine receptor binding 7/425 50/18639 0.14 6.13990588235294 0.000130677357366925 0.00749886989197894 GO:0055105 ubiquitin-protein transferase inhibitor activity 4/425 15/18639 0.266666666666667 11.6950588235294 0.000297975216559301 0.0158778222538027 GO:0042056 chemoattractant activity 6/425 42/18639 0.142857142857143 6.26521008403361 0.000355075426481251 0.0176590845436676 GO:0005201 extracellular matrix structural constituent 12/425 168/18639 0.0714285714285714 3.13260504201681 0.000486665246086837 0.0204363626827483 GO:0004029 aldehyde dehydrogenase (NAD+) activity 4/425 17/18639 0.235294117647059 10.319169550173 0.000501092961046644 0.0204363626827483 GO:0008009 chemokine activity 6/425 45/18639 0.133333333333333 5.84752941176471 0.000520497172885011 0.0204363626827483 GO:0042605 peptide antigen binding 6/425 45/18639 0.133333333333333 5.84752941176471 0.000520497172885011 0.0204363626827483 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 4/425 18/18639 0.222222222222222 9.74588235294118 0.000632730557239472 0.0236008497850323 GO:0097110 scaffold protein binding 7/425 70/18639 0.1 4.38564705882353 0.00106170069911805 0.0377156534067652 GO:0042379 chemokine receptor binding 7/425 72/18639 0.0972222222222222 4.26382352941176 0.00125493533011743 0.0425537161939821 GO:0048407 platelet-derived growth factor binding 3/425 11/18639 0.272727272727273 11.9608556149733 0.00169474137549209 0.0549685680920479 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 5/425 40/18639 0.125 5.48205882352941 0.00205315672047089 0.06381895472797 GO:0003714 transcription corepressor activity 12/425 204/18639 0.0588235294117647 2.57979238754325 0.0025913148033298 0.0768023434274259 GO:0004435 phosphatidylinositol phospholipase C activity 4/425 26/18639 0.153846153846154 6.74714932126697 0.00267675727763147 0.0768023434274259 GO:0023026 MHC class II protein complex binding 4/425 27/18639 0.148148148148148 6.49725490196078 0.00308643320106627 0.0852770062220532 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 5/425 46/18639 0.108695652173913 4.76700767263427 0.00382610596712669 0.10193839469559 GO:0004629 phospholipase C activity 4/425 29/18639 0.137931034482759 6.04916835699797 0.00402999631492837 0.103668181066778 GO:0003727 single-stranded RNA binding 7/425 89/18639 0.0786516853932584 3.44938532716457 0.0042234251900772 0.105022506393253 GO:0033218 amide binding 13/425 247/18639 0.0526315789473684 2.30823529411765 0.00455051911765277 0.109506040702225 GO:0042562 hormone binding 7/425 94/18639 0.074468085106383 3.26590738423029 0.00569751730767634 0.132823372235205 GO:0019209 kinase activator activity 9/425 148/18639 0.0608108108108108 2.66694753577107 0.00694058527181187 0.156899291296111 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 3/425 18/18639 0.166666666666667 7.30941176470588 0.00744544406636595 0.163361802162029 GO:0140313 molecular sequestering activity 5/425 55/18639 0.0909090909090909 3.98695187165775 0.00822180604189841 0.175241923064463 GO:0055106 ubiquitin-protein transferase regulator activity 4/425 36/18639 0.111111111111111 4.87294117647059 0.00882121383475783 0.182795153353593 GO:0003924 GTPase activity 15/425 331/18639 0.0453172205438066 1.98745334992003 0.00932190943397431 0.185396669081789 GO:0023023 MHC protein complex binding 4/425 37/18639 0.108108108108108 4.741240063593 0.00971611751777566 0.185396669081789 GO:0043394 proteoglycan binding 4/425 37/18639 0.108108108108108 4.741240063593 0.00971611751777566 0.185396669081789 GO:0016298 lipase activity 8/425 130/18639 0.0615384615384615 2.69885972850679 0.00994084016524336 0.185396669081789 GO:0005501 retinoid binding 4/425 38/18639 0.105263157894737 4.61647058823529 0.0106679427845956 0.189482983745436 GO:0019840 isoprenoid binding 4/425 38/18639 0.105263157894737 4.61647058823529 0.0106679427845956 0.189482983745436 GO:0001540 amyloid-beta binding 6/425 83/18639 0.072289156626506 3.1703472714387 0.0117185530629916 0.203303269418412 GO:0004620 phospholipase activity 7/425 109/18639 0.0642201834862385 2.81647058823529 0.0124348203700573 0.210826727183243 GO:0005525 GTP binding 16/425 378/18639 0.0423280423280423 1.85635854341737 0.0135443674159039 0.220419925135247 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/425 23/18639 0.130434782608696 5.72040920716112 0.0148578033307812 0.220419925135247 GO:0017134 fibroblast growth factor binding 3/425 23/18639 0.130434782608696 5.72040920716112 0.0148578033307812 0.220419925135247 GO:0031681 G-protein beta-subunit binding 3/425 23/18639 0.130434782608696 5.72040920716112 0.0148578033307812 0.220419925135247 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 3/425 23/18639 0.130434782608696 5.72040920716112 0.0148578033307812 0.220419925135247 GO:0019207 kinase regulator activity 13/425 287/18639 0.0452961672473868 1.9865300266448 0.014944682002571 0.220419925135247 GO:0048487 beta-tubulin binding 4/425 42/18639 0.0952380952380952 4.17680672268908 0.0150689224958413 0.220419925135247 GO:0035035 histone acetyltransferase binding 3/425 24/18639 0.125 5.48205882352941 0.0166986157012215 0.235040892700212 GO:0048027 mRNA 5'-UTR binding 3/425 24/18639 0.125 5.48205882352941 0.0166986157012215 0.235040892700212 GO:0008201 heparin binding 9/425 172/18639 0.0523255813953488 2.29481532147743 0.017360285688047 0.239273765055719 GO:0030020 extracellular matrix structural constituent conferring tensile strength 4/425 44/18639 0.0909090909090909 3.98695187165775 0.0176408271823922 0.239273765055719 GO:0019001 guanyl nucleotide binding 16/425 400/18639 0.04 1.75425882352941 0.0217946591910633 0.285242381693566 GO:0032561 guanyl ribonucleotide binding 16/425 400/18639 0.04 1.75425882352941 0.0217946591910633 0.285242381693566 GO:0008266 poly(U) RNA binding 3/425 27/18639 0.111111111111111 4.87294117647059 0.0229536525460964 0.290211729097861 GO:0015252 proton channel activity 3/425 27/18639 0.111111111111111 4.87294117647059 0.0229536525460964 0.290211729097861 GO:0008199 ferric iron binding 2/425 11/18639 0.181818181818182 7.97390374331551 0.0248975209949907 0.290211729097861 GO:0010854 adenylate cyclase regulator activity 2/425 11/18639 0.181818181818182 7.97390374331551 0.0248975209949907 0.290211729097861 GO:0050786 RAGE receptor binding 2/425 11/18639 0.181818181818182 7.97390374331551 0.0248975209949907 0.290211729097861 GO:0050998 nitric-oxide synthase binding 2/425 11/18639 0.181818181818182 7.97390374331551 0.0248975209949907 0.290211729097861 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/425 11/18639 0.181818181818182 7.97390374331551 0.0248975209949907 0.290211729097861 GO:0003785 actin monomer binding 3/425 29/18639 0.103448275862069 4.53687626774848 0.0277360098642185 0.293655467151594 GO:0003743 translation initiation factor activity 4/425 51/18639 0.0784313725490196 3.439723183391 0.0287077194728157 0.293655467151594 GO:0008179 adenylate cyclase binding 2/425 12/18639 0.166666666666667 7.30941176470588 0.0294327003268887 0.293655467151594 GO:0010853 cyclase activator activity 2/425 12/18639 0.166666666666667 7.30941176470588 0.0294327003268887 0.293655467151594 GO:0097371 MDM2/MDM4 family protein binding 2/425 12/18639 0.166666666666667 7.30941176470588 0.0294327003268887 0.293655467151594 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 2/425 12/18639 0.166666666666667 7.30941176470588 0.0294327003268887 0.293655467151594 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 2/425 12/18639 0.166666666666667 7.30941176470588 0.0294327003268887 0.293655467151594 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 2/425 12/18639 0.166666666666667 7.30941176470588 0.0294327003268887 0.293655467151594 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 2/425 12/18639 0.166666666666667 7.30941176470588 0.0294327003268887 0.293655467151594 GO:0001968 fibronectin binding 3/425 30/18639 0.1 4.38564705882353 0.0303102828025104 0.293655467151594 GO:0008187 poly-pyrimidine tract binding 3/425 30/18639 0.1 4.38564705882353 0.0303102828025104 0.293655467151594 GO:0031210 phosphatidylcholine binding 3/425 30/18639 0.1 4.38564705882353 0.0303102828025104 0.293655467151594 GO:0070566 adenylyltransferase activity 3/425 30/18639 0.1 4.38564705882353 0.0303102828025104 0.293655467151594 GO:0017046 peptide hormone binding 4/425 53/18639 0.0754716981132075 3.30992230854606 0.0324791768485432 0.310634178577092 GO:0019855 calcium channel inhibitor activity 2/425 13/18639 0.153846153846154 6.74714932126697 0.0342678167741497 0.313578675129821 GO:0031994 insulin-like growth factor I binding 2/425 13/18639 0.153846153846154 6.74714932126697 0.0342678167741497 0.313578675129821 GO:0033293 monocarboxylic acid binding 5/425 79/18639 0.0632911392405063 2.77572598659717 0.0343435694905791 0.313578675129821 GO:0051287 NAD binding 4/425 54/18639 0.0740740740740741 3.24862745098039 0.0344684334593101 0.313578675129821 GO:0061134 peptidase regulator activity 10/425 226/18639 0.0442477876106195 1.94055179593961 0.0350021028982078 0.314597214000759 GO:0019888 protein phosphatase regulator activity 6/425 107/18639 0.0560747663551402 2.45924134139637 0.0358217977006726 0.315733646456148 GO:0000049 tRNA binding 5/425 80/18639 0.0625 2.74102941176471 0.0359750133361563 0.315733646456148 GO:0002020 protease binding 7/425 136/18639 0.0514705882352941 2.25731833910035 0.0364382143709006 0.316080324659208 GO:0071889 14-3-3 protein binding 3/425 33/18639 0.0909090909090909 3.98695187165775 0.038757817916752 0.33233715133215 GO:0008494 translation activator activity 2/425 14/18639 0.142857142857143 6.26521008403361 0.0393869026440958 0.333629164904308 GO:0030414 peptidase inhibitor activity 8/425 169/18639 0.0473372781065089 2.07604594500522 0.0402256084373684 0.333629164904308 GO:0030295 protein kinase activator activity 7/425 139/18639 0.0503597122302158 2.20859923825645 0.0402501673477047 0.333629164904308 GO:0008135 translation factor activity, RNA binding 5/425 83/18639 0.0602409638554217 2.64195605953225 0.0411522516049005 0.337358018651162 GO:0180051 translation factor activity 5/425 84/18639 0.0595238095238095 2.61050420168067 0.0429729788620982 0.348454806860057 GO:0004129 cytochrome-c oxidase activity 2/425 15/18639 0.133333333333333 5.84752941176471 0.0447745594910411 0.35694979372985 GO:0005154 epidermal growth factor receptor binding 3/425 35/18639 0.0857142857142857 3.75912605042017 0.0449836990968016 0.35694979372985 GO:0045309 protein phosphorylated amino acid binding 4/425 59/18639 0.0677966101694915 2.97332003988036 0.045456072928064 0.35694979372985 GO:0008081 phosphoric diester hydrolase activity 5/425 87/18639 0.0574712643678161 2.52048681541582 0.0487222041625832 0.365991076951006 GO:0005159 insulin-like growth factor receptor binding 2/425 16/18639 0.125 5.48205882352941 0.0504159405587447 0.365991076951006 GO:0005521 lamin binding 2/425 16/18639 0.125 5.48205882352941 0.0504159405587447 0.365991076951006 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/425 16/18639 0.125 5.48205882352941 0.0504159405587447 0.365991076951006 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/425 16/18639 0.125 5.48205882352941 0.0504159405587447 0.365991076951006 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 2/425 16/18639 0.125 5.48205882352941 0.0504159405587447 0.365991076951006 GO:0005126 cytokine receptor binding 11/425 275/18639 0.04 1.75425882352941 0.0513895746500601 0.365991076951006 GO:0005539 glycosaminoglycan binding 10/425 242/18639 0.0413223140495868 1.81225085075352 0.0514455406289103 0.365991076951006 GO:0019208 phosphatase regulator activity 6/425 117/18639 0.0512820512820513 2.24904977375566 0.0515134893831846 0.365991076951006 GO:1990782 protein tyrosine kinase binding 6/425 117/18639 0.0512820512820513 2.24904977375566 0.0515134893831846 0.365991076951006 GO:0022853 active monoatomic ion transmembrane transporter activity 6/425 118/18639 0.0508474576271186 2.22999002991027 0.0532806483752215 0.374975129131276 GO:0140297 DNA-binding transcription factor binding 17/425 488/18639 0.0348360655737705 1.5277868852459 0.0560946028001157 0.378354624851803 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/425 17/18639 0.117647058823529 5.15958477508651 0.056296733724598 0.378354624851803 GO:0019198 transmembrane receptor protein phosphatase activity 2/425 17/18639 0.117647058823529 5.15958477508651 0.056296733724598 0.378354624851803 GO:0031489 myosin V binding 2/425 17/18639 0.117647058823529 5.15958477508651 0.056296733724598 0.378354624851803 GO:0070403 NAD+ binding 2/425 17/18639 0.117647058823529 5.15958477508651 0.056296733724598 0.378354624851803 GO:0051082 unfolded protein binding 6/425 121/18639 0.0495867768595041 2.17470102090423 0.0588010448117233 0.38247036780495 GO:0061135 endopeptidase regulator activity 8/425 184/18639 0.0434782608695652 1.90680306905371 0.060486219993425 0.38247036780495 GO:0015078 proton transmembrane transporter activity 8/425 185/18639 0.0432432432432432 1.8964960254372 0.062029025610621 0.38247036780495 GO:0003712 transcription coregulator activity 17/425 495/18639 0.0343434343434343 1.50618181818182 0.0622963882013845 0.38247036780495 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/425 18/18639 0.111111111111111 4.87294117647059 0.062403144931877 0.38247036780495 GO:0022851 GABA-gated chloride ion channel activity 2/425 18/18639 0.111111111111111 4.87294117647059 0.062403144931877 0.38247036780495 GO:0031690 adrenergic receptor binding 2/425 18/18639 0.111111111111111 4.87294117647059 0.062403144931877 0.38247036780495 GO:0050811 GABA receptor binding 2/425 18/18639 0.111111111111111 4.87294117647059 0.062403144931877 0.38247036780495 GO:0070064 proline-rich region binding 2/425 18/18639 0.111111111111111 4.87294117647059 0.062403144931877 0.38247036780495 GO:0098641 cadherin binding involved in cell-cell adhesion 2/425 18/18639 0.111111111111111 4.87294117647059 0.062403144931877 0.38247036780495 GO:0050997 quaternary ammonium group binding 3/425 40/18639 0.075 3.28923529411765 0.0625487732871365 0.38247036780495 GO:0004867 serine-type endopeptidase inhibitor activity 5/425 95/18639 0.0526315789473684 2.30823529411765 0.0661675269944153 0.394357877262897 GO:0001727 lipid kinase activity 3/425 41/18639 0.0731707317073171 3.20901004304161 0.0663912540827153 0.394357877262897 GO:0050840 extracellular matrix binding 4/425 67/18639 0.0597014925373134 2.61829675153644 0.066627095544234 0.394357877262897 GO:0019887 protein kinase regulator activity 10/425 255/18639 0.0392156862745098 1.7198615916955 0.0680920726152378 0.394357877262897 GO:0004890 GABA-A receptor activity 2/425 19/18639 0.105263157894737 4.61647058823529 0.0687218820967514 0.394357877262897 GO:0005520 insulin-like growth factor binding 2/425 19/18639 0.105263157894737 4.61647058823529 0.0687218820967514 0.394357877262897 GO:0016918 retinal binding 2/425 19/18639 0.105263157894737 4.61647058823529 0.0687218820967514 0.394357877262897 GO:0043395 heparan sulfate proteoglycan binding 2/425 19/18639 0.105263157894737 4.61647058823529 0.0687218820967514 0.394357877262897 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 4/425 68/18639 0.0588235294117647 2.57979238754325 0.0695783672444804 0.396224900491469 GO:0042578 phosphoric ester hydrolase activity 13/425 363/18639 0.0358126721763085 1.57061740398639 0.0737164420540302 0.412714294484641 GO:0048156 tau protein binding 3/425 43/18639 0.0697674418604651 3.0597537619699 0.0743903273242311 0.412714294484641 GO:0001972 retinoic acid binding 2/425 20/18639 0.1 4.38564705882353 0.0752401394770927 0.412714294484641 GO:0010851 cyclase regulator activity 2/425 20/18639 0.1 4.38564705882353 0.0752401394770927 0.412714294484641 GO:0016004 phospholipase activator activity 2/425 20/18639 0.1 4.38564705882353 0.0752401394770927 0.412714294484641 GO:0004866 endopeptidase inhibitor activity 7/425 161/18639 0.0434782608695652 1.90680306905371 0.0760856480369099 0.414305791500254 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/425 21/18639 0.0952380952380952 4.17680672268908 0.0819455824904655 0.434053765260614 GO:0051428 peptide hormone receptor binding 2/425 21/18639 0.0952380952380952 4.17680672268908 0.0819455824904655 0.434053765260614 GO:0072542 protein phosphatase activator activity 2/425 21/18639 0.0952380952380952 4.17680672268908 0.0819455824904655 0.434053765260614 GO:0005518 collagen binding 4/425 72/18639 0.0555555555555556 2.43647058823529 0.0820396526833064 0.434053765260614 GO:0140303 intramembrane lipid transporter activity 3/425 45/18639 0.0666666666666667 2.92376470588235 0.0827941425028263 0.434960776810622 GO:0015399 primary active transmembrane transporter activity 7/425 166/18639 0.0421686746987952 1.84936924167257 0.08620902390993 0.449733789068586 GO:0005125 cytokine activity 9/425 234/18639 0.0384615384615385 1.68678733031674 0.0884804464214289 0.453866057499241 GO:0008970 phospholipase A1 activity 2/425 22/18639 0.0909090909090909 3.98695187165775 0.0888263329690203 0.453866057499241 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/425 22/18639 0.0909090909090909 3.98695187165775 0.0888263329690203 0.453866057499241 GO:0016779 nucleotidyltransferase activity 6/425 136/18639 0.0441176470588235 1.93484429065744 0.0913302017819644 0.454794290282698 GO:0044325 transmembrane transporter binding 6/425 136/18639 0.0441176470588235 1.93484429065744 0.0913302017819644 0.454794290282698 GO:0140789 histone phosphatase activity 6/425 136/18639 0.0441176470588235 1.93484429065744 0.0913302017819644 0.454794290282698 GO:0001784 phosphotyrosine residue binding 3/425 47/18639 0.0638297872340425 2.7993491864831 0.0915849659830743 0.454794290282698 GO:0044183 protein folding chaperone 4/425 75/18639 0.0533333333333333 2.33901176470588 0.0920562169338972 0.454794290282698 GO:0008013 beta-catenin binding 5/425 106/18639 0.0471698113207547 2.06870144284129 0.0951059223106471 0.455539696242925 GO:0004022 alcohol dehydrogenase (NAD+) activity 2/425 23/18639 0.0869565217391304 3.81360613810742 0.0958709548393288 0.455539696242925 GO:0005158 insulin receptor binding 2/425 23/18639 0.0869565217391304 3.81360613810742 0.0958709548393288 0.455539696242925 GO:0016917 GABA receptor activity 2/425 23/18639 0.0869565217391304 3.81360613810742 0.0958709548393288 0.455539696242925 GO:0070577 lysine-acetylated histone binding 2/425 23/18639 0.0869565217391304 3.81360613810742 0.0958709548393288 0.455539696242925 GO:0099186 structural constituent of postsynapse 2/425 23/18639 0.0869565217391304 3.81360613810742 0.0958709548393288 0.455539696242925 GO:0070851 growth factor receptor binding 6/425 139/18639 0.0431654676258993 1.89308506136267 0.0988075906206409 0.460413511381905 GO:0003724 RNA helicase activity 4/425 77/18639 0.051948051948052 2.27825821237586 0.0990420569362033 0.460413511381905 GO:1901681 sulfur compound binding 10/425 275/18639 0.0363636363636364 1.5947807486631 0.0997477611424051 0.460413511381905 GO:0001222 transcription corepressor binding 3/425 49/18639 0.0612244897959184 2.68509003601441 0.100744272456518 0.460413511381905 GO:0016763 pentosyltransferase activity 3/425 49/18639 0.0612244897959184 2.68509003601441 0.100744272456518 0.460413511381905 GO:0004806 triacylglycerol lipase activity 2/425 24/18639 0.0833333333333333 3.65470588235294 0.10306844021552 0.460413511381905 GO:0050431 transforming growth factor beta binding 2/425 24/18639 0.0833333333333333 3.65470588235294 0.10306844021552 0.460413511381905 GO:0050699 WW domain binding 2/425 24/18639 0.0833333333333333 3.65470588235294 0.10306844021552 0.460413511381905 GO:0060229 lipase activator activity 2/425 24/18639 0.0833333333333333 3.65470588235294 0.10306844021552 0.460413511381905 GO:0140033 acetylation-dependent protein binding 2/425 24/18639 0.0833333333333333 3.65470588235294 0.10306844021552 0.460413511381905 GO:0003823 antigen binding 7/425 174/18639 0.0402298850574713 1.76434077079107 0.10392032388189 0.461455723904107 GO:0004721 phosphoprotein phosphatase activity 7/425 175/18639 0.04 1.75425882352941 0.106263264629573 0.46359583052003 GO:0008186 ATP-dependent activity, acting on RNA 4/425 79/18639 0.0506329113924051 2.22058078927774 0.10626660458301 0.46359583052003 GO:0046332 SMAD binding 4/425 79/18639 0.0506329113924051 2.22058078927774 0.10626660458301 0.46359583052003 GO:0008483 transaminase activity 2/425 25/18639 0.08 3.50851764705882 0.110408195894387 0.473359276650646 GO:0019211 phosphatase activator activity 2/425 25/18639 0.08 3.50851764705882 0.110408195894387 0.473359276650646 GO:0120020 cholesterol transfer activity 2/425 25/18639 0.08 3.50851764705882 0.110408195894387 0.473359276650646 GO:0008143 poly(A) binding 2/425 26/18639 0.0769230769230769 3.37357466063348 0.11788003024142 0.491276550615082 GO:0008198 ferrous iron binding 2/425 26/18639 0.0769230769230769 3.37357466063348 0.11788003024142 0.491276550615082 GO:0043548 phosphatidylinositol 3-kinase binding 2/425 26/18639 0.0769230769230769 3.37357466063348 0.11788003024142 0.491276550615082 GO:0052742 phosphatidylinositol kinase activity 2/425 26/18639 0.0769230769230769 3.37357466063348 0.11788003024142 0.491276550615082 GO:0097602 cullin family protein binding 2/425 26/18639 0.0769230769230769 3.37357466063348 0.11788003024142 0.491276550615082 GO:0005246 calcium channel regulator activity 3/425 53/18639 0.0566037735849057 2.48244173140955 0.120091317530329 0.497711793764587 GO:0001221 transcription coregulator binding 5/425 115/18639 0.0434782608695652 1.90680306905371 0.122824609638621 0.50043420365842 GO:0003925 G protein activity 3/425 54/18639 0.0555555555555556 2.43647058823529 0.125127957769801 0.50043420365842 GO:0051117 ATPase binding 4/425 84/18639 0.0476190476190476 2.08840336134454 0.125324126723724 0.50043420365842 GO:0005104 fibroblast growth factor receptor binding 2/425 27/18639 0.0740740740740741 3.24862745098039 0.125474140457046 0.50043420365842 GO:0008320 protein transmembrane transporter activity 2/425 27/18639 0.0740740740740741 3.24862745098039 0.125474140457046 0.50043420365842 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/425 27/18639 0.0740740740740741 3.24862745098039 0.125474140457046 0.50043420365842 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/425 27/18639 0.0740740740740741 3.24862745098039 0.125474140457046 0.50043420365842 GO:0009055 electron transfer activity 5/425 116/18639 0.0431034482758621 1.89036511156187 0.126114785908556 0.50043420365842 GO:0019789 SUMO transferase activity 2/425 28/18639 0.0714285714285714 3.13260504201681 0.13318110021259 0.522911056624168 GO:0097718 disordered domain specific binding 2/425 28/18639 0.0714285714285714 3.13260504201681 0.13318110021259 0.522911056624168 GO:0043236 laminin binding 2/425 29/18639 0.0689655172413793 3.02458417849899 0.140991847645802 0.550680200752715 GO:0001664 G protein-coupled receptor binding 10/425 297/18639 0.0336700336700337 1.47664884135472 0.143012378853919 0.553347395419356 GO:0003697 single-stranded DNA binding 5/425 121/18639 0.0413223140495868 1.81225085075352 0.143158240369887 0.553347395419356 GO:0061659 ubiquitin-like protein ligase activity 12/425 372/18639 0.032258064516129 1.41472485768501 0.145172725528894 0.558241511569869 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 3/425 58/18639 0.0517241379310345 2.26843813387424 0.145998877755201 0.558539296437845 GO:0001965 G-protein alpha-subunit binding 2/425 30/18639 0.0666666666666667 2.92376470588235 0.148897673706038 0.560998305983354 GO:0016769 transferase activity, transferring nitrogenous groups 2/425 30/18639 0.0666666666666667 2.92376470588235 0.148897673706038 0.560998305983354 GO:0098918 structural constituent of synapse 2/425 30/18639 0.0666666666666667 2.92376470588235 0.148897673706038 0.560998305983354 GO:0019210 kinase inhibitor activity 4/425 90/18639 0.0444444444444444 1.94917647058824 0.149928258474585 0.562042617196183 GO:0070888 E-box binding 3/425 59/18639 0.0508474576271186 2.22999002991027 0.151385099442369 0.564666420920035 GO:0047499 calcium-independent phospholipase A2 activity 2/425 31/18639 0.0645161290322581 2.82944971537002 0.156890210839429 0.582289041224946 GO:0099106 ion channel regulator activity 6/425 160/18639 0.0375 1.64461764705882 0.159551762967417 0.586005813407118 GO:0005178 integrin binding 6/425 161/18639 0.0372670807453416 1.63440263061746 0.162782709351824 0.586005813407118 GO:0051219 phosphoprotein binding 4/425 93/18639 0.043010752688172 1.88629981024668 0.162872492025995 0.586005813407118 GO:0022884 macromolecule transmembrane transporter activity 2/425 32/18639 0.0625 2.74102941176471 0.164961422004685 0.586005813407118 GO:0047498 calcium-dependent phospholipase A2 activity 2/425 32/18639 0.0625 2.74102941176471 0.164961422004685 0.586005813407118 GO:0070717 poly-purine tract binding 2/425 32/18639 0.0625 2.74102941176471 0.164961422004685 0.586005813407118 GO:0071813 lipoprotein particle binding 2/425 32/18639 0.0625 2.74102941176471 0.164961422004685 0.586005813407118 GO:0071814 protein-lipid complex binding 2/425 32/18639 0.0625 2.74102941176471 0.164961422004685 0.586005813407118 GO:0120015 sterol transfer activity 2/425 32/18639 0.0625 2.74102941176471 0.164961422004685 0.586005813407118 GO:0031490 chromatin DNA binding 5/425 128/18639 0.0390625 1.71314338235294 0.168572223329852 0.595994685327346 GO:0140311 protein sequestering activity 2/425 33/18639 0.0606060606060606 2.6579679144385 0.173103590010358 0.604917478471664 GO:0022824 transmitter-gated monoatomic ion channel activity 3/425 63/18639 0.0476190476190476 2.08840336134454 0.173528606424847 0.604917478471664 GO:0022835 transmitter-gated channel activity 3/425 63/18639 0.0476190476190476 2.08840336134454 0.173528606424847 0.604917478471664 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/425 34/18639 0.0588235294117647 2.57979238754325 0.181309307164697 0.626188625670665 GO:0051427 hormone receptor binding 2/425 34/18639 0.0588235294117647 2.57979238754325 0.181309307164697 0.626188625670665 GO:0061630 ubiquitin protein ligase activity 11/425 353/18639 0.0311614730878187 1.36663222796201 0.184821280724316 0.635376384425529 GO:0016247 channel regulator activity 6/425 168/18639 0.0357142857142857 1.5663025210084 0.186158230937068 0.637036882014005 GO:0004623 phospholipase A2 activity 2/425 35/18639 0.0571428571428571 2.50608403361345 0.189571465229418 0.641504178034813 GO:0141108 transporter regulator activity 6/425 170/18639 0.0352941176470588 1.54787543252595 0.193067926025944 0.641504178034813 GO:0005516 calmodulin binding 7/425 207/18639 0.0338164251207729 1.48306905370844 0.195076184864551 0.641504178034813 GO:0042393 histone binding 8/425 247/18639 0.0323886639676113 1.42045248868778 0.203870387463128 0.641504178034813 GO:0005522 profilin binding 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.641504178034813 GO:0005528 FK506 binding 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.641504178034813 GO:0008190 eukaryotic initiation factor 4E binding 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.641504178034813 GO:0008401 retinoic acid 4-hydroxylase activity 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.641504178034813 GO:0008519 ammonium channel activity 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.641504178034813 GO:0030957 Tat protein binding 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.641504178034813 GO:0031996 thioesterase binding 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.641504178034813 GO:0035374 chondroitin sulfate binding 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.641504178034813 GO:0043208 glycosphingolipid binding 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.641504178034813 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.641504178034813 GO:0047429 nucleoside triphosphate diphosphatase activity 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.641504178034813 GO:0050815 phosphoserine residue binding 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.641504178034813 GO:0141109 transporter activator activity 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.641504178034813 GO:0004722 protein serine/threonine phosphatase activity 4/425 103/18639 0.0388349514563107 1.70316390633923 0.208641112659181 0.641504178034813 GO:0004252 serine-type endopeptidase activity 6/425 176/18639 0.0340909090909091 1.49510695187166 0.214358665857316 0.641504178034813 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 14/425 484/18639 0.0289256198347107 1.26857559552747 0.217462555083312 0.641504178034813 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.641504178034813 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.641504178034813 GO:0008503 benzodiazepine receptor activity 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.641504178034813 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.641504178034813 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.641504178034813 GO:0032794 GTPase activating protein binding 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.641504178034813 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.641504178034813 GO:0042608 T cell receptor binding 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.641504178034813 GO:0045294 alpha-catenin binding 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.641504178034813 GO:0070990 snRNP binding 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.641504178034813 GO:0097493 structural molecule activity conferring elasticity 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.641504178034813 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/425 40/18639 0.05 2.19282352941176 0.231499837866262 0.641504178034813 GO:0061791 GTPase motor activity 2/425 40/18639 0.05 2.19282352941176 0.231499837866262 0.641504178034813 GO:1990606 membrane scission GTPase motor activity 2/425 40/18639 0.05 2.19282352941176 0.231499837866262 0.641504178034813 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/425 73/18639 0.0410958904109589 1.80232070910556 0.232220835477229 0.641504178034813 GO:0043539 protein serine/threonine kinase activator activity 3/425 73/18639 0.0410958904109589 1.80232070910556 0.232220835477229 0.641504178034813 GO:0019955 cytokine binding 5/425 144/18639 0.0347222222222222 1.52279411764706 0.232351569767294 0.641504178034813 GO:0001216 DNA-binding transcription activator activity 14/425 491/18639 0.0285132382892057 1.25048999640589 0.232760451081695 0.641504178034813 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/425 41/18639 0.0487804878048781 2.1393400286944 0.239966944726957 0.641504178034813 GO:0042287 MHC protein binding 2/425 41/18639 0.0487804878048781 2.1393400286944 0.239966944726957 0.641504178034813 GO:0140318 protein transporter activity 2/425 41/18639 0.0487804878048781 2.1393400286944 0.239966944726957 0.641504178034813 GO:0004000 adenosine deaminase activity 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.641504178034813 GO:0004032 aldose reductase (NADPH) activity 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.641504178034813 GO:0004300 enoyl-CoA hydratase activity 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.641504178034813 GO:0004859 phospholipase inhibitor activity 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.641504178034813 GO:0005095 GTPase inhibitor activity 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.641504178034813 GO:0005165 neurotrophin receptor binding 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.641504178034813 GO:0005527 macrolide binding 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.641504178034813 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.641504178034813 GO:0035497 cAMP response element binding 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.641504178034813 GO:0042301 phosphate ion binding 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.641504178034813 GO:0097677 STAT family protein binding 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.641504178034813 GO:0016755 aminoacyltransferase activity 14/425 496/18639 0.0282258064516129 1.23788425047438 0.243950329951122 0.641504178034813 GO:0016887 ATP hydrolysis activity 12/425 417/18639 0.0287769784172662 1.26205670757512 0.245187448837331 0.641504178034813 GO:1902936 phosphatidylinositol bisphosphate binding 4/425 111/18639 0.036036036036036 1.580413354531 0.247566284644023 0.641504178034813 GO:0031492 nucleosomal DNA binding 2/425 42/18639 0.0476190476190476 2.08840336134454 0.248448335676142 0.641504178034813 GO:0017022 myosin binding 3/425 76/18639 0.0394736842105263 1.73117647058824 0.250497528204222 0.641504178034813 GO:0005200 structural constituent of cytoskeleton 4/425 112/18639 0.0357142857142857 1.5663025210084 0.252542787175632 0.641504178034813 GO:0031406 carboxylic acid binding 6/425 187/18639 0.0320855614973262 1.4071594841145 0.255297203807211 0.641504178034813 GO:0008200 ion channel inhibitor activity 2/425 43/18639 0.0465116279069767 2.03983584131327 0.256938970229894 0.641504178034813 GO:0004465 lipoprotein lipase activity 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.641504178034813 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.641504178034813 GO:0008035 high-density lipoprotein particle binding 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.641504178034813 GO:0017154 semaphorin receptor activity 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.641504178034813 GO:0031432 titin binding 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.641504178034813 GO:0035673 oligopeptide transmembrane transporter activity 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.641504178034813 GO:0043560 insulin receptor substrate binding 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.641504178034813 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.641504178034813 GO:0061459 L-arginine transmembrane transporter activity 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.641504178034813 GO:0071837 HMG box domain binding 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.641504178034813 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.641504178034813 GO:0000510 H3-H4 histone complex chaperone activity 5/425 151/18639 0.033112582781457 1.45220101285547 0.262181780048188 0.641504178034813 GO:0140584 chromatin extrusion motor activity 5/425 151/18639 0.033112582781457 1.45220101285547 0.262181780048188 0.641504178034813 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/425 151/18639 0.033112582781457 1.45220101285547 0.262181780048188 0.641504178034813 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/425 151/18639 0.033112582781457 1.45220101285547 0.262181780048188 0.641504178034813 GO:0019199 transmembrane receptor protein kinase activity 3/425 78/18639 0.0384615384615385 1.68678733031674 0.262798122195535 0.641504178034813 GO:0043177 organic acid binding 6/425 189/18639 0.0317460317460317 1.39226890756303 0.262965113512894 0.641504178034813 GO:0001046 core promoter sequence-specific DNA binding 2/425 44/18639 0.0454545454545455 1.99347593582888 0.26543402929924 0.641504178034813 GO:0001223 transcription coactivator binding 2/425 44/18639 0.0454545454545455 1.99347593582888 0.26543402929924 0.641504178034813 GO:0003954 NADH dehydrogenase activity 2/425 44/18639 0.0454545454545455 1.99347593582888 0.26543402929924 0.641504178034813 GO:0016248 channel inhibitor activity 2/425 44/18639 0.0454545454545455 1.99347593582888 0.26543402929924 0.641504178034813 GO:0030547 signaling receptor inhibitor activity 2/425 44/18639 0.0454545454545455 1.99347593582888 0.26543402929924 0.641504178034813 GO:0015616 DNA translocase activity 5/425 152/18639 0.0328947368421053 1.44264705882353 0.266515942093871 0.641504178034813 GO:0140674 ATP-dependent histone chaperone activity 5/425 152/18639 0.0328947368421053 1.44264705882353 0.266515942093871 0.641504178034813 GO:0017124 SH3 domain binding 4/425 115/18639 0.0347826086956522 1.52544245524297 0.267592365515758 0.641504178034813 GO:0061775 cohesin loader activity 5/425 153/18639 0.0326797385620915 1.43321799307958 0.270866116015671 0.641504178034813 GO:0141110 transporter inhibitor activity 2/425 45/18639 0.0444444444444444 1.94917647058824 0.273928907754887 0.641504178034813 GO:0048306 calcium-dependent protein binding 3/425 80/18639 0.0375 1.64461764705882 0.275172225262469 0.641504178034813 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 10/425 349/18639 0.0286532951289398 1.25663239507838 0.275391585808316 0.641504178034813 GO:0008191 metalloendopeptidase inhibitor activity 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.641504178034813 GO:0008195 phosphatidate phosphatase activity 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.641504178034813 GO:0032036 myosin heavy chain binding 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.641504178034813 GO:0044548 S100 protein binding 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.641504178034813 GO:0061665 SUMO ligase activity 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.641504178034813 GO:0098847 sequence-specific single stranded DNA binding 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.641504178034813 GO:0033192 calmodulin-dependent protein phosphatase activity 3/425 81/18639 0.037037037037037 1.6243137254902 0.281381823693009 0.641504178034813 GO:0140791 histone H2AXS140 phosphatase activity 3/425 81/18639 0.037037037037037 1.6243137254902 0.281381823693009 0.641504178034813 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 3/425 81/18639 0.037037037037037 1.6243137254902 0.281381823693009 0.641504178034813 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 3/425 81/18639 0.037037037037037 1.6243137254902 0.281381823693009 0.641504178034813 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 3/425 81/18639 0.037037037037037 1.6243137254902 0.281381823693009 0.641504178034813 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 3/425 81/18639 0.037037037037037 1.6243137254902 0.281381823693009 0.641504178034813 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 3/425 81/18639 0.037037037037037 1.6243137254902 0.281381823693009 0.641504178034813 GO:1990439 MAP kinase serine/threonine phosphatase activity 3/425 81/18639 0.037037037037037 1.6243137254902 0.281381823693009 0.641504178034813 GO:0008236 serine-type peptidase activity 6/425 194/18639 0.0309278350515464 1.35638568829594 0.282384718628322 0.641504178034813 GO:0030291 protein serine/threonine kinase inhibitor activity 2/425 46/18639 0.0434782608695652 1.90680306905371 0.282419207214623 0.641504178034813 GO:0016791 phosphatase activity 8/425 273/18639 0.0293040293040293 1.28517129928895 0.285376939638571 0.641504178034813 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 3/425 82/18639 0.0365853658536585 1.6045050215208 0.287603849096798 0.641504178034813 GO:0033549 MAP kinase phosphatase activity 3/425 82/18639 0.0365853658536585 1.6045050215208 0.287603849096798 0.641504178034813 GO:0005504 fatty acid binding 2/425 47/18639 0.0425531914893617 1.86623279098874 0.290900729047136 0.641504178034813 GO:0099095 ligand-gated monoatomic anion channel activity 2/425 47/18639 0.0425531914893617 1.86623279098874 0.290900729047136 0.641504178034813 GO:0140359 ABC-type transporter activity 2/425 47/18639 0.0425531914893617 1.86623279098874 0.290900729047136 0.641504178034813 GO:0000774 adenyl-nucleotide exchange factor activity 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.641504178034813 GO:0005523 tropomyosin binding 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.641504178034813 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.641504178034813 GO:0033130 acetylcholine receptor binding 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.641504178034813 GO:0047372 monoacylglycerol lipase activity 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.641504178034813 GO:0050780 dopamine receptor binding 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.641504178034813 GO:0120283 protein serine/threonine kinase binding 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.641504178034813 GO:0140658 ATP-dependent chromatin remodeler activity 5/425 158/18639 0.0316455696202532 1.38786299329859 0.292832135066032 0.641504178034813 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 3/425 83/18639 0.036144578313253 1.58517363571935 0.29383639430697 0.641504178034813 GO:0017171 serine hydrolase activity 6/425 198/18639 0.0303030303030303 1.32898395721925 0.298144293856693 0.641504178034813 GO:0019787 ubiquitin-like protein transferase activity 13/425 479/18639 0.0271398747390397 1.19025911826108 0.299848243878939 0.641504178034813 GO:0004860 protein kinase inhibitor activity 3/425 84/18639 0.0357142857142857 1.5663025210084 0.300077589402646 0.641504178034813 GO:0017018 myosin phosphatase activity 3/425 84/18639 0.0357142857142857 1.5663025210084 0.300077589402646 0.641504178034813 GO:0003689 DNA clamp loader activity 5/425 160/18639 0.03125 1.37051470588235 0.301705711151827 0.641504178034813 GO:0008528 G protein-coupled peptide receptor activity 4/425 122/18639 0.0327868852459016 1.43791706846673 0.303264659480935 0.641504178034813 GO:0035254 glutamate receptor binding 2/425 49/18639 0.0408163265306122 1.7900600240096 0.307821603549142 0.641504178034813 GO:0060590 ATPase regulator activity 2/425 49/18639 0.0408163265306122 1.7900600240096 0.307821603549142 0.641504178034813 GO:0000062 fatty-acyl-CoA binding 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.641504178034813 GO:0004708 MAP kinase kinase activity 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.641504178034813 GO:0005024 transforming growth factor beta receptor activity 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.641504178034813 GO:0005149 interleukin-1 receptor binding 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.641504178034813 GO:0015378 sodium:chloride symporter activity 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.641504178034813 GO:0015562 efflux transmembrane transporter activity 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.641504178034813 GO:0016722 oxidoreductase activity, acting on metal ions 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.641504178034813 GO:0019841 retinol binding 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.641504178034813 GO:0022858 alanine transmembrane transporter activity 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.641504178034813 GO:0034450 ubiquitin-ubiquitin ligase activity 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.641504178034813 GO:0055102 lipase inhibitor activity 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.641504178034813 GO:0070411 I-SMAD binding 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.641504178034813 GO:0140328 floppase activity 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.641504178034813 GO:0016209 antioxidant activity 3/425 86/18639 0.0348837209302326 1.52987688098495 0.312578637368637 0.646395570756311 GO:0140713 histone chaperone activity 5/425 164/18639 0.0304878048780488 1.337087517934 0.31957154892717 0.646395570756311 GO:0004175 endopeptidase activity 11/425 405/18639 0.0271604938271605 1.19116339869281 0.320019347971299 0.646395570756311 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.646395570756311 GO:0008429 phosphatidylethanolamine binding 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.646395570756311 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.646395570756311 GO:0030548 acetylcholine receptor regulator activity 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.646395570756311 GO:0045236 CXCR chemokine receptor binding 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.646395570756311 GO:0070492 oligosaccharide binding 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.646395570756311 GO:1901567 fatty acid derivative binding 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.646395570756311 GO:1990226 histone methyltransferase binding 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.646395570756311 GO:0005021 vascular endothelial growth factor receptor activity 2/425 51/18639 0.0392156862745098 1.7198615916955 0.324661684431124 0.646395570756311 GO:0005048 signal sequence binding 2/425 51/18639 0.0392156862745098 1.7198615916955 0.324661684431124 0.646395570756311 GO:0016651 oxidoreductase activity, acting on NAD(P)H 3/425 88/18639 0.0340909090909091 1.49510695187166 0.325092787524918 0.646395570756311 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/425 89/18639 0.0337078651685393 1.47830799735625 0.331350502885775 0.646395570756311 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/425 89/18639 0.0337078651685393 1.47830799735625 0.331350502885775 0.646395570756311 GO:0005080 protein kinase C binding 2/425 52/18639 0.0384615384615385 1.68678733031674 0.333042866218134 0.646395570756311 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 2/425 52/18639 0.0384615384615385 1.68678733031674 0.333042866218134 0.646395570756311 GO:0030159 signaling receptor complex adaptor activity 2/425 52/18639 0.0384615384615385 1.68678733031674 0.333042866218134 0.646395570756311 GO:0046982 protein heterodimerization activity 10/425 369/18639 0.02710027100271 1.18852223816356 0.334176009070266 0.646395570756311 GO:0001653 peptide receptor activity 4/425 128/18639 0.03125 1.37051470588235 0.334236746146982 0.646395570756311 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 4/425 128/18639 0.03125 1.37051470588235 0.334236746146982 0.646395570756311 GO:0140793 histone H2AXY142 phosphatase activity 3/425 90/18639 0.0333333333333333 1.46188235294118 0.337606442348229 0.646395570756311 GO:0000400 four-way junction DNA binding 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.646395570756311 GO:0003746 translation elongation factor activity 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.646395570756311 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.646395570756311 GO:0004706 JUN kinase kinase kinase activity 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.646395570756311 GO:0004970 glutamate-gated receptor activity 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.646395570756311 GO:0008525 phosphatidylcholine transporter activity 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.646395570756311 GO:0015373 monoatomic anion:sodium symporter activity 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.646395570756311 GO:0017128 phospholipid scramblase activity 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.646395570756311 GO:0034185 apolipoprotein binding 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.646395570756311 GO:0099602 neurotransmitter receptor regulator activity 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.646395570756311 GO:0051018 protein kinase A binding 2/425 53/18639 0.0377358490566038 1.65496115427303 0.341393907343145 0.646395570756311 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/425 53/18639 0.0377358490566038 1.65496115427303 0.341393907343145 0.646395570756311 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/425 54/18639 0.037037037037037 1.6243137254902 0.349711828480582 0.657094144748749 GO:0043178 alcohol binding 3/425 92/18639 0.0326086956521739 1.43010230179028 0.350106613950199 0.657094144748749 GO:0008301 DNA binding, bending 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.657094144748749 GO:0030506 ankyrin binding 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.657094144748749 GO:0042577 lipid phosphatase activity 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.657094144748749 GO:0046624 sphingolipid transporter activity 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.657094144748749 GO:0070003 threonine-type peptidase activity 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.657094144748749 GO:0097001 ceramide binding 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.657094144748749 GO:0120227 acyl-CoA binding 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.657094144748749 GO:0098632 cell-cell adhesion mediator activity 2/425 55/18639 0.0363636363636364 1.5947807486631 0.357993801180922 0.661047959606356 GO:0051087 protein-folding chaperone binding 4/425 134/18639 0.0298507462686567 1.30914837576822 0.365342721861708 0.662961748813893 GO:0030170 pyridoxal phosphate binding 2/425 56/18639 0.0357142857142857 1.5663025210084 0.366237142567377 0.662961748813893 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/425 56/18639 0.0357142857142857 1.5663025210084 0.366237142567377 0.662961748813893 GO:0003713 transcription coactivator activity 7/425 256/18639 0.02734375 1.19920036764706 0.367049835264894 0.662961748813893 GO:0000339 RNA cap binding 1/425 20/18639 0.05 2.19282352941176 0.369694487274235 0.662961748813893 GO:0001614 purinergic nucleotide receptor activity 1/425 20/18639 0.05 2.19282352941176 0.369694487274235 0.662961748813893 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/425 20/18639 0.05 2.19282352941176 0.369694487274235 0.662961748813893 GO:0016502 nucleotide receptor activity 1/425 20/18639 0.05 2.19282352941176 0.369694487274235 0.662961748813893 GO:0016505 peptidase activator activity involved in apoptotic process 1/425 20/18639 0.05 2.19282352941176 0.369694487274235 0.662961748813893 GO:0030742 GTP-dependent protein binding 1/425 20/18639 0.05 2.19282352941176 0.369694487274235 0.662961748813893 GO:0042288 MHC class I protein binding 1/425 20/18639 0.05 2.19282352941176 0.369694487274235 0.662961748813893 GO:0140939 histone H4 methyltransferase activity 1/425 20/18639 0.05 2.19282352941176 0.369694487274235 0.662961748813893 GO:0016504 peptidase activator activity 2/425 57/18639 0.0350877192982456 1.53882352941176 0.374439310195043 0.668257716281106 GO:0070279 vitamin B6 binding 2/425 57/18639 0.0350877192982456 1.53882352941176 0.374439310195043 0.668257716281106 GO:0043021 ribonucleoprotein complex binding 5/425 177/18639 0.0282485875706215 1.23888334995015 0.378258584964157 0.673462778957664 GO:0030594 neurotransmitter receptor activity 3/425 97/18639 0.0309278350515464 1.35638568829594 0.381218304304968 0.674176756835327 GO:0008373 sialyltransferase activity 1/425 21/18639 0.0476190476190476 2.08840336134454 0.384081932513423 0.674176756835327 GO:0010314 phosphatidylinositol-5-phosphate binding 1/425 21/18639 0.0476190476190476 2.08840336134454 0.384081932513423 0.674176756835327 GO:0015174 basic amino acid transmembrane transporter activity 1/425 21/18639 0.0476190476190476 2.08840336134454 0.384081932513423 0.674176756835327 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/425 21/18639 0.0476190476190476 2.08840336134454 0.384081932513423 0.674176756835327 GO:0070182 DNA polymerase binding 1/425 21/18639 0.0476190476190476 2.08840336134454 0.384081932513423 0.674176756835327 GO:0004725 protein tyrosine phosphatase activity 3/425 98/18639 0.0306122448979592 1.3425450180072 0.387405459762666 0.676825463660302 GO:0042626 ATPase-coupled transmembrane transporter activity 3/425 98/18639 0.0306122448979592 1.3425450180072 0.387405459762666 0.676825463660302 GO:0004879 nuclear receptor activity 2/425 59/18639 0.0338983050847458 1.48666001994018 0.390710626809141 0.679417546852259 GO:0015459 potassium channel regulator activity 2/425 59/18639 0.0338983050847458 1.48666001994018 0.390710626809141 0.679417546852259 GO:0005243 gap junction channel activity 1/425 22/18639 0.0454545454545455 1.99347593582888 0.398141722967919 0.680746934415309 GO:0008093 cytoskeletal anchor activity 1/425 22/18639 0.0454545454545455 1.99347593582888 0.398141722967919 0.680746934415309 GO:0015377 chloride:monoatomic cation symporter activity 1/425 22/18639 0.0454545454545455 1.99347593582888 0.398141722967919 0.680746934415309 GO:0031683 G-protein beta/gamma-subunit complex binding 1/425 22/18639 0.0454545454545455 1.99347593582888 0.398141722967919 0.680746934415309 GO:0061133 endopeptidase activator activity 1/425 22/18639 0.0454545454545455 1.99347593582888 0.398141722967919 0.680746934415309 GO:0070034 telomerase RNA binding 1/425 22/18639 0.0454545454545455 1.99347593582888 0.398141722967919 0.680746934415309 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/425 60/18639 0.0333333333333333 1.46188235294118 0.39877534898055 0.680746934415309 GO:0098531 ligand-modulated transcription factor activity 2/425 60/18639 0.0333333333333333 1.46188235294118 0.39877534898055 0.680746934415309 GO:0019905 syntaxin binding 2/425 61/18639 0.0327868852459016 1.43791706846673 0.406790034546489 0.692843300848587 GO:0005212 structural constituent of eye lens 1/425 23/18639 0.0434782608695652 1.90680306905371 0.4118813033374 0.698326027931138 GO:0005283 amino acid:sodium symporter activity 1/425 23/18639 0.0434782608695652 1.90680306905371 0.4118813033374 0.698326027931138 GO:0019903 protein phosphatase binding 4/425 144/18639 0.0277777777777778 1.21823529411765 0.416944332872492 0.705307193475916 GO:0005096 GTPase activator activity 7/425 271/18639 0.025830258302583 1.13282396353375 0.422973135919957 0.708213683865687 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/425 24/18639 0.0416666666666667 1.82735294117647 0.425307949560091 0.708213683865687 GO:0015149 hexose transmembrane transporter activity 1/425 24/18639 0.0416666666666667 1.82735294117647 0.425307949560091 0.708213683865687 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/425 24/18639 0.0416666666666667 1.82735294117647 0.425307949560091 0.708213683865687 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/425 24/18639 0.0416666666666667 1.82735294117647 0.425307949560091 0.708213683865687 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/425 24/18639 0.0416666666666667 1.82735294117647 0.425307949560091 0.708213683865687 GO:0055056 D-glucose transmembrane transporter activity 1/425 24/18639 0.0416666666666667 1.82735294117647 0.425307949560091 0.708213683865687 GO:0000287 magnesium ion binding 6/425 230/18639 0.0260869565217391 1.14408184143223 0.427565495967472 0.709343912006595 GO:0140597 protein carrier chaperone 5/425 188/18639 0.0265957446808511 1.16639549436796 0.427888418770734 0.709343912006595 GO:0120013 lipid transfer activity 2/425 65/18639 0.0307692307692308 1.34942986425339 0.438311836784725 0.714121974632322 GO:0003707 nuclear steroid receptor activity 1/425 25/18639 0.04 1.75425882352941 0.438428772629495 0.714121974632322 GO:0004709 MAP kinase kinase kinase activity 1/425 25/18639 0.04 1.75425882352941 0.438428772629495 0.714121974632322 GO:0005251 delayed rectifier potassium channel activity 1/425 25/18639 0.04 1.75425882352941 0.438428772629495 0.714121974632322 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/425 25/18639 0.04 1.75425882352941 0.438428772629495 0.714121974632322 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/425 25/18639 0.04 1.75425882352941 0.438428772629495 0.714121974632322 GO:0019707 protein-cysteine S-acyltransferase activity 1/425 25/18639 0.04 1.75425882352941 0.438428772629495 0.714121974632322 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/425 25/18639 0.04 1.75425882352941 0.438428772629495 0.714121974632322 GO:0004842 ubiquitin-protein transferase activity 11/425 449/18639 0.0244988864142539 1.07443469147124 0.447367637662848 0.71930136507364 GO:0019842 vitamin binding 4/425 150/18639 0.0266666666666667 1.16950588235294 0.447472372006571 0.71930136507364 GO:0001217 DNA-binding transcription repressor activity 7/425 278/18639 0.0251798561151079 1.10429961912823 0.448957353290719 0.71930136507364 GO:0008066 glutamate receptor activity 1/425 26/18639 0.0384615384615385 1.68678733031674 0.451250722325018 0.71930136507364 GO:0015145 monosaccharide transmembrane transporter activity 1/425 26/18639 0.0384615384615385 1.68678733031674 0.451250722325018 0.71930136507364 GO:0019865 immunoglobulin binding 1/425 26/18639 0.0384615384615385 1.68678733031674 0.451250722325018 0.71930136507364 GO:0030507 spectrin binding 1/425 26/18639 0.0384615384615385 1.68678733031674 0.451250722325018 0.71930136507364 GO:0034237 protein kinase A regulatory subunit binding 1/425 26/18639 0.0384615384615385 1.68678733031674 0.451250722325018 0.71930136507364 GO:0050750 low-density lipoprotein particle receptor binding 1/425 26/18639 0.0384615384615385 1.68678733031674 0.451250722325018 0.71930136507364 GO:0070006 metalloaminopeptidase activity 1/425 26/18639 0.0384615384615385 1.68678733031674 0.451250722325018 0.71930136507364 GO:0016500 protein-hormone receptor activity 2/425 67/18639 0.0298507462686567 1.30914837576822 0.453727970533226 0.721708029888671 GO:0004222 metalloendopeptidase activity 3/425 110/18639 0.0272727272727273 1.19608556149733 0.460155435444789 0.729159516647553 GO:0005543 phospholipid binding 12/425 497/18639 0.0241448692152917 1.05890874659723 0.461304040195942 0.729159516647553 GO:0005548 phospholipid transporter activity 2/425 68/18639 0.0294117647058824 1.28989619377163 0.461344895251535 0.729159516647553 GO:0004364 glutathione transferase activity 1/425 27/18639 0.037037037037037 1.6243137254902 0.463780590858402 0.729916288566176 GO:0035255 ionotropic glutamate receptor binding 1/425 27/18639 0.037037037037037 1.6243137254902 0.463780590858402 0.729916288566176 GO:0005506 iron ion binding 4/425 154/18639 0.025974025974026 1.13912910618793 0.467547918460606 0.732195179923001 GO:0002039 p53 binding 2/425 69/18639 0.0289855072463768 1.27120204603581 0.468899421836939 0.732195179923001 GO:0098960 postsynaptic neurotransmitter receptor activity 2/425 69/18639 0.0289855072463768 1.27120204603581 0.468899421836939 0.732195179923001 GO:0004386 helicase activity 4/425 155/18639 0.0258064516129032 1.13177988614801 0.472526363141567 0.732195179923001 GO:0005242 inward rectifier potassium channel activity 1/425 28/18639 0.0357142857142857 1.5663025210084 0.476025016437876 0.732195179923001 GO:0045499 chemorepellent activity 1/425 28/18639 0.0357142857142857 1.5663025210084 0.476025016437876 0.732195179923001 GO:0046625 sphingolipid binding 1/425 28/18639 0.0357142857142857 1.5663025210084 0.476025016437876 0.732195179923001 GO:0051119 sugar transmembrane transporter activity 1/425 28/18639 0.0357142857142857 1.5663025210084 0.476025016437876 0.732195179923001 GO:0051537 2 iron, 2 sulfur cluster binding 1/425 28/18639 0.0357142857142857 1.5663025210084 0.476025016437876 0.732195179923001 GO:0051959 dynein light intermediate chain binding 1/425 28/18639 0.0357142857142857 1.5663025210084 0.476025016437876 0.732195179923001 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/425 28/18639 0.0357142857142857 1.5663025210084 0.476025016437876 0.732195179923001 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/425 29/18639 0.0344827586206897 1.51229208924949 0.487990486751879 0.73992053479045 GO:0005416 amino acid:monoatomic cation symporter activity 1/425 29/18639 0.0344827586206897 1.51229208924949 0.487990486751879 0.73992053479045 GO:0016417 S-acyltransferase activity 1/425 29/18639 0.0344827586206897 1.51229208924949 0.487990486751879 0.73992053479045 GO:0051861 glycolipid binding 1/425 29/18639 0.0344827586206897 1.51229208924949 0.487990486751879 0.73992053479045 GO:0097472 cyclin-dependent protein kinase activity 1/425 29/18639 0.0344827586206897 1.51229208924949 0.487990486751879 0.73992053479045 GO:0099604 ligand-gated calcium channel activity 1/425 29/18639 0.0344827586206897 1.51229208924949 0.487990486751879 0.73992053479045 GO:0106222 lncRNA binding 1/425 29/18639 0.0344827586206897 1.51229208924949 0.487990486751879 0.73992053479045 GO:0015079 potassium ion transmembrane transporter activity 4/425 160/18639 0.025 1.09641176470588 0.497146827409078 0.750027713100836 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/425 30/18639 0.0333333333333333 1.46188235294118 0.499683342374149 0.750027713100836 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/425 30/18639 0.0333333333333333 1.46188235294118 0.499683342374149 0.750027713100836 GO:0048019 receptor antagonist activity 1/425 30/18639 0.0333333333333333 1.46188235294118 0.499683342374149 0.750027713100836 GO:0051721 protein phosphatase 2A binding 1/425 30/18639 0.0333333333333333 1.46188235294118 0.499683342374149 0.750027713100836 GO:0031491 nucleosome binding 2/425 74/18639 0.027027027027027 1.18531001589825 0.505699774952383 0.756523603072643 GO:0008083 growth factor activity 4/425 162/18639 0.0246913580246914 1.08287581699346 0.506858144604537 0.756523603072643 GO:0005164 tumor necrosis factor receptor binding 1/425 31/18639 0.032258064516129 1.41472485768501 0.511109780091973 0.756523603072643 GO:0017147 Wnt-protein binding 1/425 31/18639 0.032258064516129 1.41472485768501 0.511109780091973 0.756523603072643 GO:0070273 phosphatidylinositol-4-phosphate binding 1/425 31/18639 0.032258064516129 1.41472485768501 0.511109780091973 0.756523603072643 GO:0070325 lipoprotein particle receptor binding 1/425 31/18639 0.032258064516129 1.41472485768501 0.511109780091973 0.756523603072643 GO:0072349 modified amino acid transmembrane transporter activity 1/425 31/18639 0.032258064516129 1.41472485768501 0.511109780091973 0.756523603072643 GO:0015631 tubulin binding 9/425 385/18639 0.0233766233766234 1.02521619556914 0.517130437199571 0.759149925528847 GO:0005261 monoatomic cation channel activity 8/425 341/18639 0.0234604105571848 1.0288908055891 0.517556485203038 0.759149925528847 GO:0051015 actin filament binding 5/425 209/18639 0.0239234449760766 1.04919786096257 0.519844834354161 0.759149925528847 GO:0051536 iron-sulfur cluster binding 2/425 76/18639 0.0263157894736842 1.15411764705882 0.519950078822223 0.759149925528847 GO:0098631 cell adhesion mediator activity 2/425 76/18639 0.0263157894736842 1.15411764705882 0.519950078822223 0.759149925528847 GO:0015103 inorganic anion transmembrane transporter activity 4/425 165/18639 0.0242424242424242 1.0631871657754 0.521266005738509 0.759149925528847 GO:0030515 snoRNA binding 1/425 32/18639 0.03125 1.37051470588235 0.522275856159305 0.759149925528847 GO:0031369 translation initiation factor binding 1/425 32/18639 0.03125 1.37051470588235 0.522275856159305 0.759149925528847 GO:0043425 bHLH transcription factor binding 1/425 32/18639 0.03125 1.37051470588235 0.522275856159305 0.759149925528847 GO:0015108 chloride transmembrane transporter activity 3/425 121/18639 0.0247933884297521 1.08735051045211 0.523412987361829 0.759149925528847 GO:0008094 ATP-dependent activity, acting on DNA 5/425 210/18639 0.0238095238095238 1.04420168067227 0.524078031698869 0.759149925528847 GO:0051540 metal cluster binding 2/425 77/18639 0.025974025974026 1.13912910618793 0.526971744527422 0.761862250809024 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/425 122/18639 0.0245901639344262 1.07843780135005 0.528962945207566 0.763261812620588 GO:0016874 ligase activity 4/425 167/18639 0.0239520958083832 1.05045438534695 0.530759843348467 0.763450800670708 GO:0019239 deaminase activity 1/425 33/18639 0.0303030303030303 1.32898395721925 0.533187489476459 0.763450800670708 GO:0030296 protein tyrosine kinase activator activity 1/425 33/18639 0.0303030303030303 1.32898395721925 0.533187489476459 0.763450800670708 GO:0140416 transcription regulator inhibitor activity 1/425 33/18639 0.0303030303030303 1.32898395721925 0.533187489476459 0.763450800670708 GO:0005267 potassium channel activity 3/425 124/18639 0.0241935483870968 1.06104364326376 0.539954071846569 0.768394785349865 GO:0015370 solute:sodium symporter activity 2/425 79/18639 0.0253164556962025 1.11029039463887 0.540805414010882 0.768394785349865 GO:0015020 glucuronosyltransferase activity 1/425 34/18639 0.0294117647058824 1.28989619377163 0.543850464698028 0.768394785349865 GO:0015035 protein-disulfide reductase activity 1/425 34/18639 0.0294117647058824 1.28989619377163 0.543850464698028 0.768394785349865 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/425 34/18639 0.0294117647058824 1.28989619377163 0.543850464698028 0.768394785349865 GO:0019825 oxygen binding 1/425 34/18639 0.0294117647058824 1.28989619377163 0.543850464698028 0.768394785349865 GO:0030332 cyclin binding 1/425 34/18639 0.0294117647058824 1.28989619377163 0.543850464698028 0.768394785349865 GO:0005343 organic acid:sodium symporter activity 1/425 35/18639 0.0285714285714286 1.25304201680672 0.554270435270634 0.776903843350506 GO:0140566 histone reader activity 1/425 35/18639 0.0285714285714286 1.25304201680672 0.554270435270634 0.776903843350506 GO:0030971 receptor tyrosine kinase binding 2/425 81/18639 0.0246913580246914 1.08287581699346 0.55435664034435 0.776903843350506 GO:0042826 histone deacetylase binding 3/425 127/18639 0.0236220472440945 1.03597962019453 0.556161451253757 0.776903843350506 GO:0140030 modification-dependent protein binding 4/425 173/18639 0.023121387283237 1.01402244134648 0.558670341173884 0.776903843350506 GO:0030695 GTPase regulator activity 11/425 489/18639 0.0224948875255624 0.986546373150487 0.561242408049213 0.776903843350506 GO:0060589 nucleoside-triphosphatase regulator activity 11/425 490/18639 0.0224489795918367 0.984533013205282 0.563984808458309 0.776903843350506 GO:0004033 aldo-keto reductase (NADPH) activity 1/425 36/18639 0.0277777777777778 1.21823529411765 0.56445292640211 0.776903843350506 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/425 36/18639 0.0277777777777778 1.21823529411765 0.56445292640211 0.776903843350506 GO:0016409 palmitoyltransferase activity 1/425 36/18639 0.0277777777777778 1.21823529411765 0.56445292640211 0.776903843350506 GO:0045505 dynein intermediate chain binding 1/425 36/18639 0.0277777777777778 1.21823529411765 0.56445292640211 0.776903843350506 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/425 36/18639 0.0277777777777778 1.21823529411765 0.56445292640211 0.776903843350506 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/425 36/18639 0.0277777777777778 1.21823529411765 0.56445292640211 0.776903843350506 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/425 36/18639 0.0277777777777778 1.21823529411765 0.56445292640211 0.776903843350506 GO:0035591 signaling adaptor activity 3/425 129/18639 0.0232558139534884 1.01991792065663 0.566775029919228 0.776966146556736 GO:0005254 chloride channel activity 2/425 83/18639 0.0240963855421687 1.0567824238129 0.567622721009948 0.776966146556736 GO:0030165 PDZ domain binding 2/425 83/18639 0.0240963855421687 1.0567824238129 0.567622721009948 0.776966146556736 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/425 130/18639 0.0230769230769231 1.01207239819005 0.572023238845658 0.780357982282938 GO:0005216 monoatomic ion channel activity 10/425 448/18639 0.0223214285714286 0.978939075630252 0.57219278325572 0.780357982282938 GO:0022829 wide pore channel activity 1/425 37/18639 0.027027027027027 1.18531001589825 0.574403337963638 0.781647379072838 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 6/425 268/18639 0.0223880597014925 0.981861281826163 0.575233795054944 0.781647379072838 GO:0031072 heat shock protein binding 3/425 131/18639 0.0229007633587786 1.00434665469241 0.577231923696105 0.782936391049626 GO:0051020 GTPase binding 7/425 315/18639 0.0222222222222222 0.974588235294118 0.580544417105734 0.785505476765444 GO:0005319 lipid transporter activity 4/425 178/18639 0.0224719101123595 0.985538664904164 0.581231934550302 0.785505476765444 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 3/425 132/18639 0.0227272727272727 0.996737967914438 0.582400759096376 0.7856617835188 GO:0042887 amide transmembrane transporter activity 1/425 38/18639 0.0263157894736842 1.15411764705882 0.584126947326365 0.786568055425034 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/425 86/18639 0.0232558139534884 1.01991792065663 0.586983272024854 0.788990127802776 GO:0000217 DNA secondary structure binding 1/425 39/18639 0.0256410256410256 1.12452488687783 0.593628912133972 0.795057753055553 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/425 39/18639 0.0256410256410256 1.12452488687783 0.593628912133972 0.795057753055553 GO:0022804 active transmembrane transporter activity 10/425 457/18639 0.0218818380743982 0.959660187926374 0.597485013444616 0.795996907610775 GO:0004177 aminopeptidase activity 1/425 40/18639 0.025 1.09641176470588 0.602914273012632 0.795996907610775 GO:0015036 disulfide oxidoreductase activity 1/425 40/18639 0.025 1.09641176470588 0.602914273012632 0.795996907610775 GO:0015144 carbohydrate transmembrane transporter activity 1/425 40/18639 0.025 1.09641176470588 0.602914273012632 0.795996907610775 GO:0030331 nuclear estrogen receptor binding 1/425 40/18639 0.025 1.09641176470588 0.602914273012632 0.795996907610775 GO:0071855 neuropeptide receptor binding 1/425 40/18639 0.025 1.09641176470588 0.602914273012632 0.795996907610775 GO:0071949 FAD binding 1/425 40/18639 0.025 1.09641176470588 0.602914273012632 0.795996907610775 GO:0140662 ATP-dependent protein folding chaperone 1/425 40/18639 0.025 1.09641176470588 0.602914273012632 0.795996907610775 GO:0008017 microtubule binding 6/425 276/18639 0.0217391304347826 0.953401534526854 0.603933310600132 0.795996907610775 GO:0008237 metallopeptidase activity 4/425 184/18639 0.0217391304347826 0.953401534526854 0.607413079428397 0.798058817941509 GO:0016922 nuclear receptor binding 3/425 137/18639 0.0218978102189781 0.960360669815371 0.607637276931337 0.798058817941509 GO:1901981 phosphatidylinositol phosphate binding 4/425 185/18639 0.0216216216216216 0.948248012718601 0.611678456569431 0.798152124720194 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/425 41/18639 0.024390243902439 1.0696700143472 0.611987956219773 0.798152124720194 GO:0017080 sodium channel regulator activity 1/425 41/18639 0.024390243902439 1.0696700143472 0.611987956219773 0.798152124720194 GO:0042169 SH2 domain binding 1/425 41/18639 0.024390243902439 1.0696700143472 0.611987956219773 0.798152124720194 GO:0015276 ligand-gated monoatomic ion channel activity 4/425 186/18639 0.021505376344086 0.94314990512334 0.615915230039755 0.801310835760973 GO:0140767 enzyme-substrate adaptor activity 3/425 139/18639 0.0215827338129496 0.946542530681337 0.617443862635098 0.801310835760973 GO:0016859 cis-trans isomerase activity 1/425 42/18639 0.0238095238095238 1.04420168067227 0.620854776233033 0.801310835760973 GO:0019894 kinesin binding 1/425 42/18639 0.0238095238095238 1.04420168067227 0.620854776233033 0.801310835760973 GO:0035198 miRNA binding 1/425 42/18639 0.0238095238095238 1.04420168067227 0.620854776233033 0.801310835760973 GO:0051879 Hsp90 protein binding 1/425 42/18639 0.0238095238095238 1.04420168067227 0.620854776233033 0.801310835760973 GO:0004713 protein tyrosine kinase activity 3/425 140/18639 0.0214285714285714 0.939781512605042 0.622284655613253 0.801769176316903 GO:0022834 ligand-gated channel activity 4/425 188/18639 0.0212765957446809 0.933116395494368 0.62430223069062 0.8029818346469 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/425 43/18639 0.0232558139534884 1.01991792065663 0.629519438280726 0.80829862471157 GO:0019902 phosphatase binding 4/425 190/18639 0.0210526315789474 0.923294117647059 0.632572713970233 0.810823444367343 GO:0016410 N-acyltransferase activity 2/425 94/18639 0.0212765957446809 0.933116395494368 0.635440277549447 0.813101967498949 GO:0043014 alpha-tubulin binding 1/425 44/18639 0.0227272727272727 0.996737967914438 0.637986540815179 0.814962259328979 GO:0008276 protein methyltransferase activity 2/425 95/18639 0.0210526315789474 0.923294117647059 0.641174376495379 0.817634333103509 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/425 45/18639 0.0222222222222222 0.974588235294118 0.646260577930186 0.820647305931671 GO:0051539 4 iron, 4 sulfur cluster binding 1/425 45/18639 0.0222222222222222 0.974588235294118 0.646260577930186 0.820647305931671 GO:0004896 cytokine receptor activity 2/425 96/18639 0.0208333333333333 0.913676470588235 0.646837286712899 0.820647305931671 GO:0015293 symporter activity 3/425 146/18639 0.0205479452054795 0.90116035455278 0.650446023880415 0.823824675407113 GO:0005249 voltage-gated potassium channel activity 2/425 98/18639 0.0204081632653061 0.895030012004802 0.657950594571725 0.828078213134856 GO:0008170 N-methyltransferase activity 2/425 98/18639 0.0204081632653061 0.895030012004802 0.657950594571725 0.828078213134856 GO:0008509 monoatomic anion transmembrane transporter activity 3/425 149/18639 0.0201342281879195 0.883016186340308 0.663955010535389 0.828078213134856 GO:0008188 neuropeptide receptor activity 1/425 48/18639 0.0208333333333333 0.913676470588235 0.669967721566056 0.828078213134856 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/425 48/18639 0.0208333333333333 0.913676470588235 0.669967721566056 0.828078213134856 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/425 48/18639 0.0208333333333333 0.913676470588235 0.669967721566056 0.828078213134856 GO:0032266 phosphatidylinositol-3-phosphate binding 1/425 48/18639 0.0208333333333333 0.913676470588235 0.669967721566056 0.828078213134856 GO:0038187 pattern recognition receptor activity 1/425 48/18639 0.0208333333333333 0.913676470588235 0.669967721566056 0.828078213134856 GO:0140693 molecular condensate scaffold activity 1/425 48/18639 0.0208333333333333 0.913676470588235 0.669967721566056 0.828078213134856 GO:0140104 molecular carrier activity 5/425 249/18639 0.0200803212851406 0.880652019844082 0.67401227185512 0.828078213134856 GO:0005004 GPI-linked ephrin receptor activity 1/425 49/18639 0.0204081632653061 0.895030012004802 0.677512432358075 0.828078213134856 GO:0005008 hepatocyte growth factor receptor activity 1/425 49/18639 0.0204081632653061 0.895030012004802 0.677512432358075 0.828078213134856 GO:0005009 insulin receptor activity 1/425 49/18639 0.0204081632653061 0.895030012004802 0.677512432358075 0.828078213134856 GO:0005011 macrophage colony-stimulating factor receptor activity 1/425 49/18639 0.0204081632653061 0.895030012004802 0.677512432358075 0.828078213134856 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/425 49/18639 0.0204081632653061 0.895030012004802 0.677512432358075 0.828078213134856 GO:0005020 stem cell factor receptor activity 1/425 49/18639 0.0204081632653061 0.895030012004802 0.677512432358075 0.828078213134856 GO:0008288 boss receptor activity 1/425 49/18639 0.0204081632653061 0.895030012004802 0.677512432358075 0.828078213134856 GO:0036332 placental growth factor receptor activity 1/425 49/18639 0.0204081632653061 0.895030012004802 0.677512432358075 0.828078213134856 GO:0038062 protein tyrosine kinase collagen receptor activity 1/425 49/18639 0.0204081632653061 0.895030012004802 0.677512432358075 0.828078213134856 GO:0060175 brain-derived neurotrophic factor receptor activity 1/425 49/18639 0.0204081632653061 0.895030012004802 0.677512432358075 0.828078213134856 GO:0015171 amino acid transmembrane transporter activity 2/425 102/18639 0.0196078431372549 0.859930795847751 0.679335879239319 0.828078213134856 GO:0003779 actin binding 9/425 443/18639 0.0203160270880361 0.890989244456247 0.683914059067892 0.828078213134856 GO:0005253 monoatomic anion channel activity 2/425 103/18639 0.0194174757281553 0.851581953169617 0.684508994125226 0.828078213134856 GO:0005006 epidermal growth factor receptor activity 1/425 50/18639 0.02 0.877129411764706 0.68488506367856 0.828078213134856 GO:0005007 fibroblast growth factor receptor activity 1/425 50/18639 0.02 0.877129411764706 0.68488506367856 0.828078213134856 GO:0005017 platelet-derived growth factor receptor activity 1/425 50/18639 0.02 0.877129411764706 0.68488506367856 0.828078213134856 GO:0005019 platelet-derived growth factor beta-receptor activity 1/425 50/18639 0.02 0.877129411764706 0.68488506367856 0.828078213134856 GO:0032813 tumor necrosis factor receptor superfamily binding 1/425 50/18639 0.02 0.877129411764706 0.68488506367856 0.828078213134856 GO:0005010 insulin-like growth factor receptor activity 1/425 51/18639 0.0196078431372549 0.859930795847751 0.692089531263509 0.831399018232814 GO:0005030 neurotrophin receptor activity 1/425 51/18639 0.0196078431372549 0.859930795847751 0.692089531263509 0.831399018232814 GO:0016597 amino acid binding 1/425 51/18639 0.0196078431372549 0.859930795847751 0.692089531263509 0.831399018232814 GO:0030544 Hsp70 protein binding 1/425 51/18639 0.0196078431372549 0.859930795847751 0.692089531263509 0.831399018232814 GO:0000149 SNARE binding 2/425 106/18639 0.0188679245283019 0.827480577136515 0.699619097432498 0.838666974501707 GO:0004864 protein phosphatase inhibitor activity 1/425 53/18639 0.0188679245283019 0.827480577136515 0.706009195693126 0.838666974501707 GO:0005003 ephrin receptor activity 1/425 53/18639 0.0188679245283019 0.827480577136515 0.706009195693126 0.838666974501707 GO:0005005 transmembrane-ephrin receptor activity 1/425 53/18639 0.0188679245283019 0.827480577136515 0.706009195693126 0.838666974501707 GO:0016860 intramolecular oxidoreductase activity 1/425 53/18639 0.0188679245283019 0.827480577136515 0.706009195693126 0.838666974501707 GO:0038064 collagen receptor activity 1/425 53/18639 0.0188679245283019 0.827480577136515 0.706009195693126 0.838666974501707 GO:0140296 general transcription initiation factor binding 1/425 53/18639 0.0188679245283019 0.827480577136515 0.706009195693126 0.838666974501707 GO:0015485 cholesterol binding 1/425 54/18639 0.0185185185185185 0.812156862745098 0.712731787527325 0.839965108207558 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/425 54/18639 0.0185185185185185 0.812156862745098 0.712731787527325 0.839965108207558 GO:0017069 snRNA binding 1/425 54/18639 0.0185185185185185 0.812156862745098 0.712731787527325 0.839965108207558 GO:0050661 NADP binding 1/425 54/18639 0.0185185185185185 0.812156862745098 0.712731787527325 0.839965108207558 GO:0140463 chromatin-protein adaptor activity 1/425 54/18639 0.0185185185185185 0.812156862745098 0.712731787527325 0.839965108207558 GO:0019212 phosphatase inhibitor activity 1/425 56/18639 0.0178571428571429 0.783151260504202 0.725720352531781 0.853923317016891 GO:0043022 ribosome binding 2/425 112/18639 0.0178571428571429 0.783151260504202 0.728039081727433 0.855302606249866 GO:0016757 glycosyltransferase activity 5/425 267/18639 0.0187265917602996 0.82128222075347 0.731632589656435 0.857247956519144 GO:0004601 peroxidase activity 1/425 57/18639 0.0175438596491228 0.769411764705882 0.731993228287794 0.857247956519144 GO:0061980 regulatory RNA binding 1/425 58/18639 0.0172413793103448 0.756146044624746 0.738122970940775 0.863071687024794 GO:0035401 histone H3Y41 kinase activity 2/425 115/18639 0.0173913043478261 0.762721227621483 0.74137605995973 0.86416646989056 GO:0140801 histone H2AXY142 kinase activity 2/425 115/18639 0.0173913043478261 0.762721227621483 0.74137605995973 0.86416646989056 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/425 59/18639 0.0169491525423729 0.74333000997009 0.744112838943045 0.864654482634753 GO:0031593 polyubiquitin modification-dependent protein binding 1/425 59/18639 0.0169491525423729 0.74333000997009 0.744112838943045 0.864654482634753 GO:0015294 solute:monoatomic cation symporter activity 2/425 116/18639 0.0172413793103448 0.756146044624746 0.745695961576586 0.865146481082634 GO:0001098 basal transcription machinery binding 1/425 60/18639 0.0166666666666667 0.730941176470588 0.749966016739019 0.867402555794276 GO:0001099 basal RNA polymerase II transcription machinery binding 1/425 60/18639 0.0166666666666667 0.730941176470588 0.749966016739019 0.867402555794276 GO:0015026 coreceptor activity 1/425 61/18639 0.0163934426229508 0.718958534233366 0.755685616442228 0.869971404114046 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/425 61/18639 0.0163934426229508 0.718958534233366 0.755685616442228 0.869971404114046 GO:0016836 hydro-lyase activity 1/425 61/18639 0.0163934426229508 0.718958534233366 0.755685616442228 0.869971404114046 GO:0015179 L-amino acid transmembrane transporter activity 1/425 62/18639 0.0161290322580645 0.707362428842505 0.761274679474419 0.875055332647021 GO:1901682 sulfur compound transmembrane transporter activity 1/425 63/18639 0.0158730158730159 0.696134453781513 0.766736178167609 0.879977213712363 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 4/425 229/18639 0.0174672489082969 0.76605188800411 0.769737648579301 0.881395250547416 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/425 122/18639 0.0163934426229508 0.718958534233366 0.770334722998546 0.881395250547416 GO:0031267 small GTPase binding 5/425 283/18639 0.0176678445229682 0.774849303679069 0.776351842973954 0.885608593014282 GO:0038024 cargo receptor activity 1/425 65/18639 0.0153846153846154 0.674714932126697 0.77728803577592 0.885608593014282 GO:0035091 phosphatidylinositol binding 5/425 284/18639 0.0176056338028169 0.772120961060481 0.77894681116448 0.885608593014282 GO:0008235 metalloexopeptidase activity 1/425 66/18639 0.0151515151515152 0.664491978609626 0.782384007822611 0.885608593014282 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/425 67/18639 0.0149253731343284 0.654574187884109 0.787363644751238 0.885608593014282 GO:0042054 histone methyltransferase activity 1/425 67/18639 0.0149253731343284 0.654574187884109 0.787363644751238 0.885608593014282 GO:0030145 manganese ion binding 1/425 68/18639 0.0147058823529412 0.644948096885813 0.792229596236309 0.885608593014282 GO:0032934 sterol binding 1/425 68/18639 0.0147058823529412 0.644948096885813 0.792229596236309 0.885608593014282 GO:1990841 promoter-specific chromatin binding 1/425 68/18639 0.0147058823529412 0.644948096885813 0.792229596236309 0.885608593014282 GO:0016279 protein-lysine N-methyltransferase activity 1/425 69/18639 0.0144927536231884 0.635601023017903 0.796984451742182 0.885608593014282 GO:0016278 lysine N-methyltransferase activity 1/425 70/18639 0.0142857142857143 0.626521008403361 0.801630741888093 0.885608593014282 GO:0005262 calcium channel activity 2/425 131/18639 0.0152671755725191 0.669564436461608 0.803389856528749 0.885608593014282 GO:0140299 molecular sensor activity 1/425 71/18639 0.0140845070422535 0.617696768848384 0.806170939782302 0.885608593014282 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 4/425 243/18639 0.0164609053497942 0.721917211328976 0.807973440726541 0.885608593014282 GO:0004676 3-phosphoinositide-dependent protein kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0004711 ribosomal protein S6 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0035175 histone H3S10 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0035979 histone H2AXS139 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0044022 histone H3S28 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0044023 histone H4S1 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0044024 histone H2AS1 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0044025 histone H2BS14 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0072354 histone H3T3 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0072371 histone H2AS121 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0072518 Rho-dependent protein serine/threonine kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0140823 histone H2BS36 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0140855 histone H3S57 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0140995 histone H2A kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0140997 histone H4 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0140998 histone H2B kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:1990244 histone H2AT120 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.885608593014282 GO:0004677 DNA-dependent protein kinase activity 4/425 246/18639 0.016260162601626 0.713113342898135 0.815459144024228 0.885608593014282 GO:0140857 histone H3T45 kinase activity 4/425 246/18639 0.016260162601626 0.713113342898135 0.815459144024228 0.885608593014282 GO:0035402 histone H3T11 kinase activity 4/425 247/18639 0.0161943319838057 0.710226244343891 0.817900717336463 0.885608593014282 GO:0035403 histone H3T6 kinase activity 4/425 247/18639 0.0161943319838057 0.710226244343891 0.817900717336463 0.885608593014282 GO:0003684 damaged DNA binding 1/425 74/18639 0.0135135135135135 0.592655007949126 0.819178875550225 0.885608593014282 GO:0035064 methylated histone binding 1/425 74/18639 0.0135135135135135 0.592655007949126 0.819178875550225 0.885608593014282 GO:0099094 ligand-gated monoatomic cation channel activity 2/425 136/18639 0.0147058823529412 0.644948096885813 0.819871665337063 0.885608593014282 GO:0004679 AMP-activated protein kinase activity 4/425 248/18639 0.0161290322580645 0.707362428842505 0.820315734279985 0.885608593014282 GO:0019003 GDP binding 1/425 75/18639 0.0133333333333333 0.584752941176471 0.823318330324862 0.887565714483161 GO:0140034 methylation-dependent protein binding 1/425 76/18639 0.0131578947368421 0.577058823529412 0.827363240344898 0.890639216879212 GO:0106310 protein serine kinase activity 6/425 361/18639 0.0166204986149584 0.728916408668731 0.834794067497444 0.897343478894947 GO:0020037 heme binding 2/425 142/18639 0.0140845070422535 0.617696768848384 0.838009642504098 0.899221542644665 GO:0016835 carbon-oxygen lyase activity 1/425 79/18639 0.0126582278481013 0.555145197319434 0.838952002252932 0.899221542644665 GO:0022843 voltage-gated monoatomic cation channel activity 2/425 143/18639 0.013986013986014 0.61337721102427 0.840867151106572 0.899981197597565 GO:0001618 virus receptor activity 1/425 81/18639 0.0123456790123457 0.541437908496732 0.846243332559684 0.903084022165834 GO:0015101 organic cation transmembrane transporter activity 1/425 81/18639 0.0123456790123457 0.541437908496732 0.846243332559684 0.903084022165834 GO:0008168 methyltransferase activity 3/425 204/18639 0.0147058823529412 0.644948096885813 0.847397876026922 0.903084022165834 GO:0140272 exogenous protein binding 1/425 82/18639 0.0121951219512195 0.534835007173601 0.84976454086134 0.904314333070699 GO:0015085 calcium ion transmembrane transporter activity 2/425 147/18639 0.0136054421768707 0.596686674669868 0.851846210363808 0.905238280529061 GO:0022836 gated channel activity 5/425 318/18639 0.0157232704402516 0.689567147613763 0.85400687636854 0.906243427839162 GO:0004527 exonuclease activity 1/425 84/18639 0.0119047619047619 0.522100840336134 0.856567428288921 0.907669462362976 GO:0050660 flavin adenine dinucleotide binding 1/425 86/18639 0.0116279069767442 0.509958960328317 0.863062962719482 0.913255276863452 GO:0046906 tetrapyrrole binding 2/425 152/18639 0.0131578947368421 0.577058823529412 0.864599085063895 0.913584868920207 GO:0003774 cytoskeletal motor activity 2/425 153/18639 0.0130718954248366 0.573287197231834 0.867025931910435 0.914148636586956 GO:0004674 protein serine/threonine kinase activity 7/425 433/18639 0.0161662817551963 0.708996060317892 0.86758342453561 0.914148636586956 GO:0004197 cysteine-type endopeptidase activity 1/425 88/18639 0.0113636363636364 0.498368983957219 0.869264999025776 0.914628616746444 GO:0016741 transferase activity, transferring one-carbon groups 3/425 215/18639 0.013953488372093 0.611950752393981 0.871334477621802 0.915514817332203 GO:0140375 immune receptor activity 2/425 156/18639 0.0128205128205128 0.562262443438914 0.874069098284199 0.917096409732788 GO:0052689 carboxylic ester hydrolase activity 1/425 92/18639 0.0108695652173913 0.476700767263427 0.880840909016118 0.922903536693854 GO:0140097 catalytic activity, acting on DNA 5/425 336/18639 0.0148809523809524 0.652626050420168 0.88432296584432 0.924284358784736 GO:0030246 carbohydrate binding 4/425 280/18639 0.0142857142857143 0.626521008403361 0.88463677234893 0.924284358784736 GO:0046873 metal ion transmembrane transporter activity 7/425 450/18639 0.0155555555555556 0.682211764705882 0.891136584940898 0.928546395471324 GO:0015081 sodium ion transmembrane transporter activity 2/425 164/18639 0.0121951219512195 0.534835007173601 0.891205387610547 0.928546395471324 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/425 167/18639 0.0119760479041916 0.525227192673477 0.897054743214351 0.933337292103076 GO:0005085 guanyl-nucleotide exchange factor activity 3/425 230/18639 0.0130434782608696 0.572040920716113 0.898612430622157 0.933655812317728 GO:0043130 ubiquitin binding 1/425 100/18639 0.01 0.438564705882353 0.901014533576483 0.934849571694098 GO:0008238 exopeptidase activity 1/425 102/18639 0.00980392156862745 0.429965397923875 0.905501045843219 0.938199694720891 GO:0005244 voltage-gated monoatomic ion channel activity 2/425 173/18639 0.0115606936416185 0.50701122067324 0.907885968768959 0.939050149823287 GO:0141003 histone H2AX kinase activity 5/425 354/18639 0.0141242937853107 0.619441674975075 0.909094527365728 0.939050149823287 GO:0022832 voltage-gated channel activity 2/425 175/18639 0.0114285714285714 0.501216806722689 0.911253259149818 0.939050149823287 GO:0045182 translation regulator activity 5/425 356/18639 0.0140449438202247 0.615961665565102 0.911538902805539 0.939050149823287 GO:0140996 histone H3 kinase activity 5/425 357/18639 0.0140056022408964 0.614236282748394 0.912739393669552 0.939050149823287 GO:0004497 monooxygenase activity 1/425 106/18639 0.00943396226415094 0.413740288568258 0.913874542589419 0.939050149823287 GO:0035173 histone kinase activity 5/425 360/18639 0.0138888888888889 0.609117647058824 0.916255660102886 0.939181688305094 GO:0004843 cysteine-type deubiquitinase activity 1/425 108/18639 0.00925925925925926 0.406078431372549 0.917779424630581 0.939181688305094 GO:0005496 steroid binding 1/425 108/18639 0.00925925925925926 0.406078431372549 0.917779424630581 0.939181688305094 GO:0016853 isomerase activity 2/425 180/18639 0.0111111111111111 0.487294117647059 0.919174062052749 0.939320342864864 GO:0008234 cysteine-type peptidase activity 2/425 187/18639 0.0106951871657754 0.4690531613715 0.929153186367247 0.946982514869801 GO:0101005 deubiquitinase activity 1/425 115/18639 0.00869565217391304 0.381360613810742 0.930106856069744 0.946982514869801 GO:0046943 carboxylic acid transmembrane transporter activity 2/425 188/18639 0.0106382978723404 0.466558197747184 0.930480138605314 0.946982514869801 GO:0005342 organic acid transmembrane transporter activity 2/425 189/18639 0.0105820105820106 0.464089635854342 0.931783603006096 0.947017122401291 GO:0032182 ubiquitin-like protein binding 1/425 120/18639 0.00833333333333333 0.365470588235294 0.937765943664629 0.951800536018794 GO:0003730 mRNA 3'-UTR binding 3/425 262/18639 0.0114503816793893 0.502173327346206 0.940166566204007 0.952940568462214 GO:0016829 lyase activity 2/425 200/18639 0.01 0.438564705882353 0.944676078165637 0.956073606122283 GO:0008514 organic anion transmembrane transporter activity 3/425 269/18639 0.0111524163568773 0.489105619943145 0.946850981529998 0.956073606122283 GO:0019783 ubiquitin-like protein peptidase activity 1/425 127/18639 0.0078740157480315 0.345326540064845 0.947102406064835 0.956073606122283 GO:0004518 nuclease activity 2/425 209/18639 0.00956937799043062 0.419679144385027 0.953466904640724 0.961197717381054 GO:0015291 secondary active transmembrane transporter activity 3/425 287/18639 0.0104529616724739 0.458430006148801 0.960986656292847 0.967471046686186 GO:0008194 UDP-glycosyltransferase activity 1/425 145/18639 0.00689655172413793 0.302458417849899 0.965183182740157 0.970386326582422 GO:0140098 catalytic activity, acting on RNA 4/425 387/18639 0.0103359173126615 0.453296853625171 0.978072840402547 0.982021990498385 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/425 181/18639 0.00552486187845304 0.242300942476438 0.984935380501899 0.987583056255936 GO:0016758 hexosyltransferase activity 1/425 197/18639 0.0050761421319797 0.222621678112869 0.989624117554951 0.990952472075159 GO:0030371 translation repressor activity 1/425 329/18639 0.00303951367781155 0.133302342213481 0.999527254055639 0.999527254055639