ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0015078 proton transmembrane transporter activity 31/727 185/18639 0.167567567567568 4.29613740287743 6.21397137528616e-12 5.49936466712825e-09 GO:0023023 MHC protein complex binding 14/727 37/18639 0.378378378378378 9.70095542585226 4.42466640041198e-11 1.9579148821823e-08 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 18/727 68/18639 0.264705882352941 6.78659276640505 7.24279683198751e-11 2.13662506543632e-08 GO:0023026 MHC class II protein complex binding 12/727 27/18639 0.444444444444444 11.39477303989 1.14992596678529e-10 2.54421120151246e-08 GO:0022853 active monoatomic ion transmembrane transporter activity 23/727 118/18639 0.194915254237288 4.99728393910428 1.48358930417186e-10 2.62595306838419e-08 GO:0008137 NADH dehydrogenase (ubiquinone) activity 13/727 41/18639 0.317073170731707 8.12919783943369 2.78974284231956e-09 4.11487069242135e-07 GO:0009055 electron transfer activity 21/727 116/18639 0.181034482758621 4.6414053977138 3.81245876501541e-09 4.82003715291234e-07 GO:0003954 NADH dehydrogenase activity 13/727 44/18639 0.295454545454545 7.57493435038139 7.37637967864227e-09 8.16012001949802e-07 GO:0015399 primary active transmembrane transporter activity 23/727 166/18639 0.13855421686747 3.55228617358015 1.30698866535792e-07 1.28520552093529e-05 GO:0003725 double-stranded RNA binding 15/727 75/18639 0.2 5.12764786795048 1.64407080371363e-07 1.45500266128656e-05 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 13/727 58/18639 0.224137931034483 5.74650192097899 2.70750631847737e-07 2.17831190168407e-05 GO:0031625 ubiquitin protein ligase binding 32/727 302/18639 0.105960264900662 2.71663463202675 3.13287237376915e-07 2.31049337565475e-05 GO:0044389 ubiquitin-like protein ligase binding 33/727 322/18639 0.102484472049689 2.6275214230181 4.43013177902565e-07 3.01589740341361e-05 GO:0042277 peptide binding 28/727 249/18639 0.112449799196787 2.88301486551433 5.14914401161895e-07 3.25499460734484e-05 GO:0031386 protein tag activity 7/727 15/18639 0.466666666666667 11.9645116918845 6.53051485913656e-07 3.61219103145991e-05 GO:0141047 molecular tag activity 7/727 15/18639 0.466666666666667 11.9645116918845 6.53051485913656e-07 3.61219103145991e-05 GO:0042605 peptide antigen binding 11/727 45/18639 0.244444444444444 6.26712517193948 8.89814912676861e-07 4.63227175128836e-05 GO:0016651 oxidoreductase activity, acting on NAD(P)H 14/727 88/18639 0.159090909090909 4.07881080405152 7.37672966711562e-06 0.000362689208633185 GO:0032395 MHC class II receptor activity 5/727 10/18639 0.5 12.8191196698762 1.90575937210427e-05 0.000887682654901199 GO:0140375 immune receptor activity 18/727 156/18639 0.115384615384615 2.95825838535605 3.87212565692766e-05 0.00171341560319049 GO:0044325 transmembrane transporter binding 16/727 136/18639 0.117647058823529 3.01626345173558 8.13623553238036e-05 0.00342884211721744 GO:0045296 cadherin binding 28/727 334/18639 0.0838323353293413 2.14931347758403 0.000127117556365585 0.00511359260834286 GO:0005178 integrin binding 17/727 161/18639 0.105590062111801 2.70714328432168 0.000189057542076179 0.00705488800470479 GO:0030515 snoRNA binding 7/727 32/18639 0.21875 5.60836485557084 0.000191318996737757 0.00705488800470479 GO:0140313 molecular sequestering activity 9/727 55/18639 0.163636363636364 4.19534825559585 0.000252899153560828 0.00864861285143558 GO:0050699 WW domain binding 6/727 24/18639 0.25 6.4095598349381 0.000254083541398107 0.00864861285143558 GO:0140297 DNA-binding transcription factor binding 35/727 488/18639 0.0717213114754098 1.83880814936749 0.000413942267512759 0.0135681076573627 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 5/727 18/18639 0.277777777777778 7.12173314993122 0.000499383712817672 0.0157840923515586 GO:0051015 actin filament binding 19/727 209/18639 0.0909090909090909 2.33074903088658 0.000559338643049582 0.0168202240567394 GO:0043021 ribonucleoprotein complex binding 17/727 177/18639 0.096045197740113 2.46242976709486 0.000576760070456825 0.0168202240567394 GO:0034511 U3 snoRNA binding 4/727 11/18639 0.363636363636364 9.32299612354633 0.000608188892447074 0.0168202240567394 GO:0048407 platelet-derived growth factor binding 4/727 11/18639 0.363636363636364 9.32299612354633 0.000608188892447074 0.0168202240567394 GO:0048487 beta-tubulin binding 7/727 42/18639 0.166666666666667 4.27303988995873 0.00109346281290138 0.0285165939368679 GO:0003925 G protein activity 8/727 54/18639 0.148148148148148 3.79825767996332 0.00109555276141639 0.0285165939368679 GO:0003779 actin binding 31/727 443/18639 0.0699774266365688 1.79409801248832 0.00128665939416296 0.0325341018238347 GO:0003735 structural constituent of ribosome 16/727 175/18639 0.0914285714285714 2.34406759677736 0.00139680519011178 0.0337909047260571 GO:0005200 structural constituent of cytoskeleton 12/727 112/18639 0.107142857142857 2.74695421497347 0.00141272709024193 0.0337909047260571 GO:0019956 chemokine binding 6/727 33/18639 0.181818181818182 4.66149806177317 0.00155096346910751 0.0361211228989513 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 5/727 23/18639 0.217391304347826 5.57353029125052 0.00166837555600073 0.0371709392993528 GO:0016530 metallochaperone activity 4/727 14/18639 0.285714285714286 7.32521123992926 0.00168004245420804 0.0371709392993528 GO:0015035 protein-disulfide reductase activity 6/727 34/18639 0.176470588235294 4.52439517760337 0.00182208369523632 0.0384232666727536 GO:0001786 phosphatidylserine binding 8/727 59/18639 0.135593220338983 3.47637143589863 0.00196871499424486 0.0384232666727536 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 5/727 24/18639 0.208333333333333 5.34129986244842 0.00204055766510669 0.0384232666727536 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 5/727 24/18639 0.208333333333333 5.34129986244842 0.00204055766510669 0.0384232666727536 GO:0042625 ATPase-coupled ion transmembrane transporter activity 5/727 24/18639 0.208333333333333 5.34129986244842 0.00204055766510669 0.0384232666727536 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 5/727 24/18639 0.208333333333333 5.34129986244842 0.00204055766510669 0.0384232666727536 GO:0046961 proton-transporting ATPase activity, rotational mechanism 5/727 24/18639 0.208333333333333 5.34129986244842 0.00204055766510669 0.0384232666727536 GO:0004129 cytochrome-c oxidase activity 4/727 15/18639 0.266666666666667 6.83686382393397 0.00222080689451833 0.0409461271176818 GO:0002020 protease binding 13/727 136/18639 0.0955882352941176 2.45071405453516 0.00256820716218853 0.0463849660925888 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 25/727 349/18639 0.0716332378223496 1.8365500959708 0.00267675365863961 0.047378539757921 GO:0016675 oxidoreductase activity, acting on a heme group of donors 4/727 16/18639 0.25 6.4095598349381 0.00287052125810796 0.0498119865377558 GO:0004112 cyclic-nucleotide phosphodiesterase activity 5/727 26/18639 0.192307692307692 4.93043064226008 0.00296109711175433 0.0503955950750496 GO:0015252 proton channel activity 5/727 27/18639 0.185185185185185 4.74782209995415 0.0035191375350168 0.058762956952639 GO:0015036 disulfide oxidoreductase activity 6/727 40/18639 0.15 3.84573590096286 0.00426731504155748 0.0698400186622288 GO:0043022 ribosome binding 11/727 112/18639 0.0982142857142857 2.51804136372568 0.00434034014285038 0.0698400186622288 GO:1990381 ubiquitin-specific protease binding 4/727 18/18639 0.222222222222222 5.69738651994498 0.00453619392020257 0.0716880646317727 GO:0017069 snRNA binding 7/727 54/18639 0.12962962962963 3.3234754699679 0.00479784999593073 0.0740797150985416 GO:0035250 UDP-galactosyltransferase activity 5/727 29/18639 0.172413793103448 4.42038609306076 0.00485494178046939 0.0740797150985416 GO:0001540 amyloid-beta binding 9/727 83/18639 0.108433734939759 2.78005004888882 0.00497801969108527 0.0746702953662791 GO:0001221 transcription coregulator binding 11/727 115/18639 0.0956521739130435 2.45235332815023 0.0053013199747559 0.0781944696276495 GO:0003924 GTPase activity 23/727 331/18639 0.0694864048338369 1.78150907798884 0.00559174406899302 0.0811040167219735 GO:0005031 tumor necrosis factor receptor activity 3/727 10/18639 0.3 7.69147180192572 0.00577350627512354 0.0811040167219735 GO:0031996 thioesterase binding 3/727 10/18639 0.3 7.69147180192572 0.00577350627512354 0.0811040167219735 GO:0019208 phosphatase regulator activity 11/727 117/18639 0.094017094017094 2.41043275843826 0.00603017319853496 0.0833859887609912 GO:0016209 antioxidant activity 9/727 86/18639 0.104651162790698 2.6830715588113 0.00628496871946041 0.0855722664111148 GO:0016504 peptidase activator activity 7/727 57/18639 0.12280701754386 3.14855570839065 0.00647971470530657 0.086887083548429 GO:0043014 alpha-tubulin binding 6/727 44/18639 0.136363636363636 3.49612354632987 0.00688263433782513 0.0909124087906752 GO:0008378 galactosyltransferase activity 5/727 32/18639 0.15625 4.00597489683631 0.00747914956689447 0.0973389318632589 GO:0042608 T cell receptor binding 3/727 11/18639 0.272727272727273 6.99224709265975 0.0077105002936272 0.0974827537122867 GO:0070990 snRNP binding 3/727 11/18639 0.272727272727273 6.99224709265975 0.0077105002936272 0.0974827537122867 GO:0001846 opsonin binding 4/727 21/18639 0.19047619047619 4.88347415995284 0.00808729757162909 0.100806455646363 GO:0140311 protein sequestering activity 5/727 33/18639 0.151515151515152 3.8845817181443 0.00853775422721357 0.104943229042833 GO:0044183 protein folding chaperone 8/727 75/18639 0.106666666666667 2.73474552957359 0.00870690784768901 0.105556348564449 GO:0140104 molecular carrier activity 18/727 249/18639 0.072289156626506 1.85336669925921 0.009063658645177 0.108396458121374 GO:0010853 cyclase activator activity 3/727 12/18639 0.25 6.4095598349381 0.00998592408803579 0.117833904238822 GO:0001222 transcription corepressor binding 6/727 49/18639 0.122448979591837 3.13937624568397 0.0115791045753718 0.134835625647422 GO:0035591 signaling adaptor activity 11/727 129/18639 0.0852713178294574 2.18620645532772 0.0121964668543298 0.140180170988076 GO:0004896 cytokine receptor activity 9/727 96/18639 0.09375 2.40358493810179 0.0126001566604791 0.141267311583497 GO:0005035 death receptor activity 3/727 13/18639 0.230769230769231 5.91651677071209 0.0126103023899393 0.141267311583497 GO:0019843 rRNA binding 7/727 65/18639 0.107692307692308 2.76104115966564 0.0130766861337233 0.143059639716034 GO:0019957 C-C chemokine binding 4/727 24/18639 0.166666666666667 4.27303988995873 0.0130935941435014 0.143059639716034 GO:0001848 complement binding 4/727 25/18639 0.16 4.10211829436039 0.0151171637550174 0.163154755160858 GO:0005246 calcium channel regulator activity 6/727 53/18639 0.113207547169811 2.90244218940593 0.0166895328608352 0.17795465761252 GO:0001637 G protein-coupled chemoattractant receptor activity 4/727 26/18639 0.153846153846154 3.94434451380806 0.0173273576901561 0.178310599485909 GO:0004950 chemokine receptor activity 4/727 26/18639 0.153846153846154 3.94434451380806 0.0173273576901561 0.178310599485909 GO:0097602 cullin family protein binding 4/727 26/18639 0.153846153846154 3.94434451380806 0.0173273576901561 0.178310599485909 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 6/727 54/18639 0.111111111111111 2.84869325997249 0.0181759932189483 0.184893724123784 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 3/727 15/18639 0.2 5.12764786795048 0.0189339012418847 0.184914303741897 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 3/727 15/18639 0.2 5.12764786795048 0.0189339012418847 0.184914303741897 GO:0016846 carbon-sulfur lyase activity 3/727 15/18639 0.2 5.12764786795048 0.0189339012418847 0.184914303741897 GO:0003823 antigen binding 13/727 174/18639 0.0747126436781609 1.91550064032633 0.0190137871644211 0.184914303741897 GO:0008320 protein transmembrane transporter activity 4/727 27/18639 0.148148148148148 3.79825767996332 0.0197287872823543 0.189782355922647 GO:0051082 unfolded protein binding 10/727 121/18639 0.0826446280991736 2.11886275535144 0.0200133467215055 0.190449589769166 GO:0042287 MHC protein binding 5/727 41/18639 0.121951219512195 3.12661455362834 0.0209101577428623 0.196866910664182 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 3/727 16/18639 0.1875 4.80716987620358 0.0226408350842947 0.208720198433342 GO:0017070 U6 snRNA binding 3/727 16/18639 0.1875 4.80716987620358 0.0226408350842947 0.208720198433342 GO:0004601 peroxidase activity 6/727 57/18639 0.105263157894737 2.69876203576341 0.0231725749341319 0.211419884708317 GO:0019888 protein phosphatase regulator activity 9/727 107/18639 0.0841121495327103 2.15648742110067 0.0239998307460284 0.214917168350396 GO:0005525 GTP binding 23/727 378/18639 0.0608465608465608 1.55999868998493 0.0240415815442816 0.214917168350396 GO:0019001 guanyl nucleotide binding 24/727 400/18639 0.06 1.53829436038514 0.0248920988678773 0.218113935624469 GO:0032561 guanyl ribonucleotide binding 24/727 400/18639 0.06 1.53829436038514 0.0248920988678773 0.218113935624469 GO:0072341 modified amino acid binding 8/727 91/18639 0.0879120879120879 2.25391115074746 0.0256371540586623 0.221015192275556 GO:0004550 nucleoside diphosphate kinase activity 3/727 17/18639 0.176470588235294 4.52439517760337 0.0267126301055233 0.221015192275556 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 3/727 17/18639 0.176470588235294 4.52439517760337 0.0267126301055233 0.221015192275556 GO:0005092 GDP-dissociation inhibitor activity 3/727 17/18639 0.176470588235294 4.52439517760337 0.0267126301055233 0.221015192275556 GO:0008429 phosphatidylethanolamine binding 3/727 17/18639 0.176470588235294 4.52439517760337 0.0267126301055233 0.221015192275556 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 6/727 59/18639 0.101694915254237 2.60727857692397 0.0269713454980339 0.221015192275556 GO:0045309 protein phosphorylated amino acid binding 6/727 59/18639 0.101694915254237 2.60727857692397 0.0269713454980339 0.221015192275556 GO:0017022 myosin binding 7/727 76/18639 0.0921052631578947 2.36141678129298 0.0285603844232219 0.231889359766527 GO:0003714 transcription corepressor activity 14/727 204/18639 0.0686274509803922 1.75948701351242 0.0293246922294598 0.235930478391563 GO:0016757 glycosyltransferase activity 17/727 267/18639 0.0636704119850187 1.63239726133255 0.0331446808025678 0.264261644236689 GO:0046332 SMAD binding 7/727 79/18639 0.0886075949367089 2.27174272630717 0.0343186276178005 0.266546176108864 GO:0022884 macromolecule transmembrane transporter activity 4/727 32/18639 0.125 3.20477991746905 0.0347232116893806 0.266546176108864 GO:0051059 NF-kappaB binding 4/727 32/18639 0.125 3.20477991746905 0.0347232116893806 0.266546176108864 GO:0140142 nucleocytoplasmic carrier activity 4/727 32/18639 0.125 3.20477991746905 0.0347232116893806 0.266546176108864 GO:0022804 active transmembrane transporter activity 26/727 457/18639 0.0568927789934354 1.45863068453734 0.0356453152851075 0.266546176108864 GO:0003756 protein disulfide isomerase activity 3/727 19/18639 0.157894736842105 4.04814305364512 0.0359436118617837 0.266546176108864 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 3/727 19/18639 0.157894736842105 4.04814305364512 0.0359436118617837 0.266546176108864 GO:0070003 threonine-type peptidase activity 3/727 19/18639 0.157894736842105 4.04814305364512 0.0359436118617837 0.266546176108864 GO:0048306 calcium-dependent protein binding 7/727 80/18639 0.0875 2.24334594222834 0.0363972869213468 0.266546176108864 GO:0000287 magnesium ion binding 15/727 230/18639 0.0652173913043478 1.67205908737516 0.0364430365075395 0.266546176108864 GO:0001618 virus receptor activity 7/727 81/18639 0.0864197530864197 2.21565031331194 0.0385573056383365 0.279698487622359 GO:0140272 exogenous protein binding 7/727 82/18639 0.0853658536585366 2.18863018753984 0.0407996187638647 0.293299687109638 GO:0010851 cyclase regulator activity 3/727 20/18639 0.15 3.84573590096286 0.0410950974029324 0.293299687109638 GO:0016922 nuclear receptor binding 10/727 137/18639 0.072992700729927 1.87140433136879 0.0420882870949182 0.296078728288954 GO:0008376 acetylgalactosaminyltransferase activity 4/727 34/18639 0.117647058823529 3.01626345173558 0.0421535816546985 0.296078728288954 GO:0016758 hexosyltransferase activity 13/727 197/18639 0.065989847715736 1.69186350972985 0.0454068777427728 0.314828376153435 GO:0051117 ATPase binding 7/727 84/18639 0.0833333333333333 2.13651994497937 0.0455344996018527 0.314828376153435 GO:0009931 calcium-dependent protein serine/threonine kinase activity 3/727 21/18639 0.142857142857143 3.66260561996463 0.0465963973748163 0.319672958734205 GO:0032934 sterol binding 6/727 68/18639 0.0882352941176471 2.26219758880168 0.049062442927461 0.334002015313869 GO:0030159 signaling receptor complex adaptor activity 5/727 52/18639 0.0961538461538462 2.46521532113004 0.0513446550675641 0.34174464160596 GO:0061133 endopeptidase activator activity 3/727 22/18639 0.136363636363636 3.49612354632987 0.0524403330557212 0.34174464160596 GO:0070034 telomerase RNA binding 3/727 22/18639 0.136363636363636 3.49612354632987 0.0524403330557212 0.34174464160596 GO:0008081 phosphoric diester hydrolase activity 7/727 87/18639 0.0804597701149425 2.06284684342835 0.0532731179732031 0.34174464160596 GO:0016860 intramolecular oxidoreductase activity 5/727 53/18639 0.0943396226415094 2.41870182450494 0.0549545636307651 0.34174464160596 GO:0030957 Tat protein binding 2/727 10/18639 0.2 5.12764786795048 0.0555449015450614 0.34174464160596 GO:0035256 G protein-coupled glutamate receptor binding 2/727 10/18639 0.2 5.12764786795048 0.0555449015450614 0.34174464160596 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/727 10/18639 0.2 5.12764786795048 0.0555449015450614 0.34174464160596 GO:0043208 glycosphingolipid binding 2/727 10/18639 0.2 5.12764786795048 0.0555449015450614 0.34174464160596 GO:0047429 nucleoside triphosphate diphosphatase activity 2/727 10/18639 0.2 5.12764786795048 0.0555449015450614 0.34174464160596 GO:0050815 phosphoserine residue binding 2/727 10/18639 0.2 5.12764786795048 0.0555449015450614 0.34174464160596 GO:0070513 death domain binding 2/727 10/18639 0.2 5.12764786795048 0.0555449015450614 0.34174464160596 GO:0097177 mitochondrial ribosome binding 2/727 10/18639 0.2 5.12764786795048 0.0555449015450614 0.34174464160596 GO:0019955 cytokine binding 10/727 144/18639 0.0694444444444444 1.78043328748281 0.0556059077867325 0.34174464160596 GO:0008194 UDP-glycosyltransferase activity 10/727 145/18639 0.0689655172413793 1.7681544372243 0.0577452063399362 0.342172249576374 GO:0019207 kinase regulator activity 17/727 287/18639 0.0592334494773519 1.51864135461948 0.0581221692824675 0.342172249576374 GO:0004602 glutathione peroxidase activity 3/727 23/18639 0.130434782608696 3.34411817475031 0.0586186698045141 0.342172249576374 GO:0016493 C-C chemokine receptor activity 3/727 23/18639 0.130434782608696 3.34411817475031 0.0586186698045141 0.342172249576374 GO:0031681 G-protein beta-subunit binding 3/727 23/18639 0.130434782608696 3.34411817475031 0.0586186698045141 0.342172249576374 GO:0099186 structural constituent of postsynapse 3/727 23/18639 0.130434782608696 3.34411817475031 0.0586186698045141 0.342172249576374 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 5/727 54/18639 0.0925925925925926 2.37391104997707 0.0587074789789097 0.342172249576374 GO:0000146 microfilament motor activity 4/727 38/18639 0.105263157894737 2.69876203576341 0.0594882847941742 0.342172249576374 GO:0043531 ADP binding 4/727 38/18639 0.105263157894737 2.69876203576341 0.0594882847941742 0.342172249576374 GO:0004857 enzyme inhibitor activity 23/727 416/18639 0.0552884615384615 1.41749880964977 0.0595687992535151 0.342172249576374 GO:0061134 peptidase regulator activity 14/727 226/18639 0.0619469026548673 1.58820951662183 0.0599284730896474 0.342172249576374 GO:0005496 steroid binding 8/727 108/18639 0.0740740740740741 1.89912883998166 0.0604261244501016 0.342802052168846 GO:0005518 collagen binding 6/727 72/18639 0.0833333333333333 2.13651994497937 0.0616403960331331 0.347463378912884 GO:0016776 phosphotransferase activity, phosphate group as acceptor 4/727 39/18639 0.102564102564103 2.62956300920537 0.0643309790965964 0.354937394627241 GO:0005540 hyaluronic acid binding 3/727 24/18639 0.125 3.20477991746905 0.0651222520418016 0.354937394627241 GO:0001851 complement component C3b binding 2/727 11/18639 0.181818181818182 4.66149806177317 0.0661747684898245 0.354937394627241 GO:0010854 adenylate cyclase regulator activity 2/727 11/18639 0.181818181818182 4.66149806177317 0.0661747684898245 0.354937394627241 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/727 11/18639 0.181818181818182 4.66149806177317 0.0661747684898245 0.354937394627241 GO:0019864 IgG binding 2/727 11/18639 0.181818181818182 4.66149806177317 0.0661747684898245 0.354937394627241 GO:0050786 RAGE receptor binding 2/727 11/18639 0.181818181818182 4.66149806177317 0.0661747684898245 0.354937394627241 GO:0050998 nitric-oxide synthase binding 2/727 11/18639 0.181818181818182 4.66149806177317 0.0661747684898245 0.354937394627241 GO:0019212 phosphatase inhibitor activity 5/727 56/18639 0.0892857142857143 2.28912851247789 0.0666411820994693 0.355285820229098 GO:0140662 ATP-dependent protein folding chaperone 4/727 40/18639 0.1 2.56382393397524 0.0693733043590392 0.367636972202094 GO:0031072 heat shock protein binding 9/727 131/18639 0.0687022900763359 1.7614057561662 0.0707838377811417 0.372267627435268 GO:0051219 phosphoprotein binding 7/727 93/18639 0.0752688172043011 1.92975995030394 0.0710883943915935 0.372267627435268 GO:0120020 cholesterol transfer activity 3/727 25/18639 0.12 3.07658872077029 0.0719411277172722 0.373743419959602 GO:0019003 GDP binding 6/727 75/18639 0.08 2.05105914718019 0.072214830297279 0.373743419959602 GO:0042562 hormone binding 7/727 94/18639 0.074468085106383 1.9092305891305 0.0743635260083312 0.37437210695416 GO:0061650 ubiquitin-like protein conjugating enzyme activity 4/727 41/18639 0.0975609756097561 2.50129164290267 0.07461256345268 0.37437210695416 GO:0140318 protein transporter activity 4/727 41/18639 0.0975609756097561 2.50129164290267 0.07461256345268 0.37437210695416 GO:0004000 adenosine deaminase activity 2/727 12/18639 0.166666666666667 4.27303988995873 0.0774125373701823 0.37437210695416 GO:0005049 nuclear export signal receptor activity 2/727 12/18639 0.166666666666667 4.27303988995873 0.0774125373701823 0.37437210695416 GO:0005078 MAP-kinase scaffold activity 2/727 12/18639 0.166666666666667 4.27303988995873 0.0774125373701823 0.37437210695416 GO:0015368 calcium:monoatomic cation antiporter activity 2/727 12/18639 0.166666666666667 4.27303988995873 0.0774125373701823 0.37437210695416 GO:0016801 hydrolase activity, acting on ether bonds 2/727 12/18639 0.166666666666667 4.27303988995873 0.0774125373701823 0.37437210695416 GO:0016803 ether hydrolase activity 2/727 12/18639 0.166666666666667 4.27303988995873 0.0774125373701823 0.37437210695416 GO:0017166 vinculin binding 2/727 12/18639 0.166666666666667 4.27303988995873 0.0774125373701823 0.37437210695416 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/727 12/18639 0.166666666666667 4.27303988995873 0.0774125373701823 0.37437210695416 GO:0035259 nuclear glucocorticoid receptor binding 2/727 12/18639 0.166666666666667 4.27303988995873 0.0774125373701823 0.37437210695416 GO:0008198 ferrous iron binding 3/727 26/18639 0.115384615384615 2.95825838535605 0.0790646629382004 0.376194767205954 GO:0050681 nuclear androgen receptor binding 3/727 26/18639 0.115384615384615 2.95825838535605 0.0790646629382004 0.376194767205954 GO:0070412 R-SMAD binding 3/727 26/18639 0.115384615384615 2.95825838535605 0.0790646629382004 0.376194767205954 GO:0070063 RNA polymerase binding 5/727 59/18639 0.0847457627118644 2.17273214743664 0.0796015024537402 0.376723688083209 GO:0030246 carbohydrate binding 16/727 280/18639 0.0571428571428571 1.46504224798585 0.0826795494029888 0.389209580966197 GO:0004364 glutathione transferase activity 3/727 27/18639 0.111111111111111 2.84869325997249 0.0864816473951811 0.40495374573934 GO:0019855 calcium channel inhibitor activity 2/727 13/18639 0.153846153846154 3.94434451380806 0.0891947619120447 0.411132105688331 GO:0031432 titin binding 2/727 13/18639 0.153846153846154 3.94434451380806 0.0891947619120447 0.411132105688331 GO:0043560 insulin receptor substrate binding 2/727 13/18639 0.153846153846154 3.94434451380806 0.0891947619120447 0.411132105688331 GO:0019205 nucleobase-containing compound kinase activity 4/727 44/18639 0.0909090909090909 2.33074903088658 0.0914795970313086 0.417316718416021 GO:0030020 extracellular matrix structural constituent conferring tensile strength 4/727 44/18639 0.0909090909090909 2.33074903088658 0.0914795970313086 0.417316718416021 GO:0046875 ephrin receptor binding 3/727 28/18639 0.107142857142857 2.74695421497347 0.0941803911843382 0.425253296929282 GO:0046966 nuclear thyroid hormone receptor binding 3/727 28/18639 0.107142857142857 2.74695421497347 0.0941803911843382 0.425253296929282 GO:0043130 ubiquitin binding 7/727 100/18639 0.07 1.79467675378267 0.0958435825136389 0.430310090843825 GO:0030971 receptor tyrosine kinase binding 6/727 81/18639 0.0740740740740741 1.89912883998166 0.096272766087093 0.430310090843825 GO:0032182 ubiquitin-like protein binding 8/727 120/18639 0.0666666666666667 1.70921595598349 0.0973188200804366 0.430484285845314 GO:0008009 chemokine activity 4/727 45/18639 0.0888888888888889 2.27895460797799 0.0974726161601965 0.430484285845314 GO:0005507 copper ion binding 5/727 63/18639 0.0793650793650794 2.03478089998035 0.0988113514787783 0.430484285845314 GO:0005161 platelet-derived growth factor receptor binding 2/727 14/18639 0.142857142857143 3.66260561996463 0.101462008501984 0.430484285845314 GO:0008191 metalloendopeptidase inhibitor activity 2/727 14/18639 0.142857142857143 3.66260561996463 0.101462008501984 0.430484285845314 GO:0008195 phosphatidate phosphatase activity 2/727 14/18639 0.142857142857143 3.66260561996463 0.101462008501984 0.430484285845314 GO:0019763 immunoglobulin receptor activity 2/727 14/18639 0.142857142857143 3.66260561996463 0.101462008501984 0.430484285845314 GO:0032036 myosin heavy chain binding 2/727 14/18639 0.142857142857143 3.66260561996463 0.101462008501984 0.430484285845314 GO:0042043 neurexin family protein binding 2/727 14/18639 0.142857142857143 3.66260561996463 0.101462008501984 0.430484285845314 GO:0044548 S100 protein binding 2/727 14/18639 0.142857142857143 3.66260561996463 0.101462008501984 0.430484285845314 GO:0003785 actin monomer binding 3/727 29/18639 0.103448275862069 2.65223165583646 0.102148813590413 0.430484285845314 GO:0051861 glycolipid binding 3/727 29/18639 0.103448275862069 2.65223165583646 0.102148813590413 0.430484285845314 GO:0001784 phosphotyrosine residue binding 4/727 47/18639 0.0851063829787234 2.18197781614914 0.109989292793906 0.456455392806272 GO:0005504 fatty acid binding 4/727 47/18639 0.0851063829787234 2.18197781614914 0.109989292793906 0.456455392806272 GO:0043495 protein-membrane adaptor activity 4/727 47/18639 0.0851063829787234 2.18197781614914 0.109989292793906 0.456455392806272 GO:0098918 structural constituent of synapse 3/727 30/18639 0.1 2.56382393397524 0.110374524362195 0.456455392806272 GO:0051020 GTPase binding 17/727 315/18639 0.053968253968254 1.38365101198664 0.111291657816964 0.458107521711688 GO:0000774 adenyl-nucleotide exchange factor activity 2/727 15/18639 0.133333333333333 3.41843191196699 0.114158640388153 0.463442186896858 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/727 15/18639 0.133333333333333 3.41843191196699 0.114158640388153 0.463442186896858 GO:0120283 protein serine/threonine kinase binding 2/727 15/18639 0.133333333333333 3.41843191196699 0.114158640388153 0.463442186896858 GO:0008327 methyl-CpG binding 3/727 31/18639 0.0967741935483871 2.48111993610507 0.118844897980565 0.47841397559871 GO:0015631 tubulin binding 20/727 385/18639 0.051948051948052 1.33185658907805 0.118927767945442 0.47841397559871 GO:0042578 phosphoric ester hydrolase activity 19/727 363/18639 0.0523415977961433 1.34194641172258 0.119708646396773 0.479376253670336 GO:0016247 channel regulator activity 10/727 168/18639 0.0595238095238095 1.52608567498526 0.121918860168236 0.484933384992885 GO:0019902 phosphatase binding 11/727 190/18639 0.0578947368421053 1.48431911966988 0.124793555895956 0.484933384992885 GO:0005159 insulin-like growth factor receptor binding 2/727 16/18639 0.125 3.20477991746905 0.127232612574418 0.484933384992885 GO:0005521 lamin binding 2/727 16/18639 0.125 3.20477991746905 0.127232612574418 0.484933384992885 GO:0008142 oxysterol binding 2/727 16/18639 0.125 3.20477991746905 0.127232612574418 0.484933384992885 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/727 16/18639 0.125 3.20477991746905 0.127232612574418 0.484933384992885 GO:0034450 ubiquitin-ubiquitin ligase activity 2/727 16/18639 0.125 3.20477991746905 0.127232612574418 0.484933384992885 GO:0043023 ribosomal large subunit binding 2/727 16/18639 0.125 3.20477991746905 0.127232612574418 0.484933384992885 GO:0055102 lipase inhibitor activity 2/727 16/18639 0.125 3.20477991746905 0.127232612574418 0.484933384992885 GO:0070411 I-SMAD binding 2/727 16/18639 0.125 3.20477991746905 0.127232612574418 0.484933384992885 GO:0120015 sterol transfer activity 3/727 32/18639 0.09375 2.40358493810179 0.127547141389998 0.484933384992885 GO:0031490 chromatin DNA binding 8/727 128/18639 0.0625 1.60238995873453 0.127671727348409 0.484933384992885 GO:0141108 transporter regulator activity 10/727 170/18639 0.0588235294117647 1.50813172586779 0.128850301652117 0.487318448556082 GO:0019239 deaminase activity 3/727 33/18639 0.0909090909090909 2.33074903088658 0.136468355636444 0.51091479262535 GO:0003743 translation initiation factor activity 4/727 51/18639 0.0784313725490196 2.01084230115705 0.137009986014536 0.51091479262535 GO:0005048 signal sequence binding 4/727 51/18639 0.0784313725490196 2.01084230115705 0.137009986014536 0.51091479262535 GO:0097110 scaffold protein binding 5/727 70/18639 0.0714285714285714 1.83130280998231 0.137398554400942 0.51091479262535 GO:0017110 nucleoside diphosphate phosphatase activity 2/727 17/18639 0.117647058823529 3.01626345173558 0.140635276903604 0.512190206006952 GO:0032977 membrane insertase activity 2/727 17/18639 0.117647058823529 3.01626345173558 0.140635276903604 0.512190206006952 GO:0051787 misfolded protein binding 2/727 17/18639 0.117647058823529 3.01626345173558 0.140635276903604 0.512190206006952 GO:0070492 oligosaccharide binding 2/727 17/18639 0.117647058823529 3.01626345173558 0.140635276903604 0.512190206006952 GO:1990226 histone methyltransferase binding 2/727 17/18639 0.117647058823529 3.01626345173558 0.140635276903604 0.512190206006952 GO:0005080 protein kinase C binding 4/727 52/18639 0.0769230769230769 1.97217225690403 0.14414876359345 0.5228346548369 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 3/727 34/18639 0.0882352941176471 2.26219758880168 0.145595591828226 0.525926933746856 GO:0004864 protein phosphatase inhibitor activity 4/727 53/18639 0.0754716981132075 1.93496145960396 0.151429922774078 0.544049893267146 GO:0051087 protein-folding chaperone binding 8/727 134/18639 0.0597014925373134 1.53064115461208 0.153291299296562 0.544049893267146 GO:0000400 four-way junction DNA binding 2/727 18/18639 0.111111111111111 2.84869325997249 0.154321196848731 0.544049893267146 GO:0031690 adrenergic receptor binding 2/727 18/18639 0.111111111111111 2.84869325997249 0.154321196848731 0.544049893267146 GO:0050811 GABA receptor binding 2/727 18/18639 0.111111111111111 2.84869325997249 0.154321196848731 0.544049893267146 GO:0070064 proline-rich region binding 2/727 18/18639 0.111111111111111 2.84869325997249 0.154321196848731 0.544049893267146 GO:0043015 gamma-tubulin binding 3/727 35/18639 0.0857142857142857 2.19756337197878 0.154915901811662 0.544049893267146 GO:0015485 cholesterol binding 4/727 54/18639 0.0740740740740741 1.89912883998166 0.158847718277691 0.555653085674928 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/727 19/18639 0.105263157894737 2.69876203576341 0.168247971553078 0.577129669862301 GO:0042577 lipid phosphatase activity 2/727 19/18639 0.105263157894737 2.69876203576341 0.168247971553078 0.577129669862301 GO:0050145 nucleoside monophosphate kinase activity 2/727 19/18639 0.105263157894737 2.69876203576341 0.168247971553078 0.577129669862301 GO:0140036 ubiquitin-modified protein reader activity 2/727 19/18639 0.105263157894737 2.69876203576341 0.168247971553078 0.577129669862301 GO:1990380 K48-linked deubiquitinase activity 2/727 19/18639 0.105263157894737 2.69876203576341 0.168247971553078 0.577129669862301 GO:0033218 amide binding 13/727 247/18639 0.0526315789473684 1.34938101788171 0.169530733525801 0.579284552781212 GO:1990782 protein tyrosine kinase binding 7/727 117/18639 0.0598290598290598 1.5339117553698 0.172774282188917 0.588032589407868 GO:0099106 ion channel regulator activity 9/727 160/18639 0.05625 1.44215096286107 0.173782963590184 0.588032589407868 GO:0030280 structural constituent of skin epidermis 3/727 37/18639 0.0810810810810811 2.07877616268263 0.174084224208883 0.588032589407868 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/727 20/18639 0.1 2.56382393397524 0.182376068680872 0.602249331278252 GO:0016004 phospholipase activator activity 2/727 20/18639 0.1 2.56382393397524 0.182376068680872 0.602249331278252 GO:0016505 peptidase activator activity involved in apoptotic process 2/727 20/18639 0.1 2.56382393397524 0.182376068680872 0.602249331278252 GO:0042288 MHC class I protein binding 2/727 20/18639 0.1 2.56382393397524 0.182376068680872 0.602249331278252 GO:0043024 ribosomal small subunit binding 2/727 20/18639 0.1 2.56382393397524 0.182376068680872 0.602249331278252 GO:0061608 nuclear import signal receptor activity 2/727 20/18639 0.1 2.56382393397524 0.182376068680872 0.602249331278252 GO:0005126 cytokine receptor binding 14/727 275/18639 0.0509090909090909 1.30521945729649 0.188479971285748 0.62009209883973 GO:0008234 cysteine-type peptidase activity 10/727 187/18639 0.053475935828877 1.37102884169799 0.195770720938345 0.631135055895348 GO:0008373 sialyltransferase activity 2/727 21/18639 0.0952380952380952 2.44173707997642 0.196668665660456 0.631135055895348 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/727 21/18639 0.0952380952380952 2.44173707997642 0.196668665660456 0.631135055895348 GO:0051010 microtubule plus-end binding 2/727 21/18639 0.0952380952380952 2.44173707997642 0.196668665660456 0.631135055895348 GO:0070182 DNA polymerase binding 2/727 21/18639 0.0952380952380952 2.44173707997642 0.196668665660456 0.631135055895348 GO:0072542 protein phosphatase activator activity 2/727 21/18639 0.0952380952380952 2.44173707997642 0.196668665660456 0.631135055895348 GO:0070888 E-box binding 4/727 59/18639 0.0677966101694915 1.73818571794932 0.197779465853087 0.631135055895348 GO:0019887 protein kinase regulator activity 13/727 255/18639 0.0509803921568627 1.30704749575208 0.198125695557919 0.631135055895348 GO:0001217 DNA-binding transcription repressor activity 14/727 278/18639 0.0503597122302158 1.29113435523933 0.199006368515437 0.631135055895348 GO:0019903 protein phosphatase binding 8/727 144/18639 0.0555555555555556 1.42434662998624 0.20087648267393 0.631135055895348 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/727 40/18639 0.075 1.92286795048143 0.203965818009073 0.631135055895348 GO:0061791 GTPase motor activity 3/727 40/18639 0.075 1.92286795048143 0.203965818009073 0.631135055895348 GO:1990606 membrane scission GTPase motor activity 3/727 40/18639 0.075 1.92286795048143 0.203965818009073 0.631135055895348 GO:0033192 calmodulin-dependent protein phosphatase activity 5/727 81/18639 0.0617283950617284 1.58260736665138 0.208840633271574 0.631135055895348 GO:0140791 histone H2AXS140 phosphatase activity 5/727 81/18639 0.0617283950617284 1.58260736665138 0.208840633271574 0.631135055895348 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 5/727 81/18639 0.0617283950617284 1.58260736665138 0.208840633271574 0.631135055895348 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 5/727 81/18639 0.0617283950617284 1.58260736665138 0.208840633271574 0.631135055895348 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 5/727 81/18639 0.0617283950617284 1.58260736665138 0.208840633271574 0.631135055895348 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 5/727 81/18639 0.0617283950617284 1.58260736665138 0.208840633271574 0.631135055895348 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 5/727 81/18639 0.0617283950617284 1.58260736665138 0.208840633271574 0.631135055895348 GO:1990439 MAP kinase serine/threonine phosphatase activity 5/727 81/18639 0.0617283950617284 1.58260736665138 0.208840633271574 0.631135055895348 GO:0005201 extracellular matrix structural constituent 9/727 168/18639 0.0535714285714286 1.37347710748674 0.210402159916819 0.631135055895348 GO:0008970 phospholipase A1 activity 2/727 22/18639 0.0909090909090909 2.33074903088658 0.21109149892093 0.631135055895348 GO:0034062 5'-3' RNA polymerase activity 2/727 22/18639 0.0909090909090909 2.33074903088658 0.21109149892093 0.631135055895348 GO:0097747 RNA polymerase activity 2/727 22/18639 0.0909090909090909 2.33074903088658 0.21109149892093 0.631135055895348 GO:0140035 ubiquitin-like protein reader activity 2/727 22/18639 0.0909090909090909 2.33074903088658 0.21109149892093 0.631135055895348 GO:0140517 protein-RNA adaptor activity 2/727 22/18639 0.0909090909090909 2.33074903088658 0.21109149892093 0.631135055895348 GO:0004722 protein serine/threonine phosphatase activity 6/727 103/18639 0.058252427184466 1.49348967027684 0.21403140797394 0.637770357094063 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 5/727 82/18639 0.0609756097560976 1.56330727681417 0.215865854582306 0.63893405118843 GO:0033549 MAP kinase phosphatase activity 5/727 82/18639 0.0609756097560976 1.56330727681417 0.215865854582306 0.63893405118843 GO:0003712 transcription coregulator activity 23/727 495/18639 0.0464646464646465 1.19127172689759 0.221653035541839 0.653387867064127 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 5/727 83/18639 0.0602409638554217 1.54447224938268 0.222963995314538 0.653387867064127 GO:0008135 translation factor activity, RNA binding 5/727 83/18639 0.0602409638554217 1.54447224938268 0.222963995314538 0.653387867064127 GO:0031492 nucleosomal DNA binding 3/727 42/18639 0.0714285714285714 1.83130280998231 0.224495780554666 0.653548571680523 GO:0051879 Hsp90 protein binding 3/727 42/18639 0.0714285714285714 1.83130280998231 0.224495780554666 0.653548571680523 GO:0005158 insulin receptor binding 2/727 23/18639 0.0869565217391304 2.22941211650021 0.225612720741541 0.654646747069718 GO:0004860 protein kinase inhibitor activity 5/727 84/18639 0.0595238095238095 1.52608567498526 0.230131368296321 0.661254093968324 GO:0017018 myosin phosphatase activity 5/727 84/18639 0.0595238095238095 1.52608567498526 0.230131368296321 0.661254093968324 GO:0180051 translation factor activity 5/727 84/18639 0.0595238095238095 1.52608567498526 0.230131368296321 0.661254093968324 GO:0008200 ion channel inhibitor activity 3/727 43/18639 0.0697674418604651 1.78871437254087 0.234907768137801 0.672794093210207 GO:0030552 cAMP binding 2/727 24/18639 0.0833333333333333 2.13651994497937 0.240202763350608 0.681344376811821 GO:0048027 mRNA 5'-UTR binding 2/727 24/18639 0.0833333333333333 2.13651994497937 0.240202763350608 0.681344376811821 GO:0060229 lipase activator activity 2/727 24/18639 0.0833333333333333 2.13651994497937 0.240202763350608 0.681344376811821 GO:0001046 core promoter sequence-specific DNA binding 3/727 44/18639 0.0681818181818182 1.74806177316494 0.245402512365105 0.687282352668095 GO:0001223 transcription coactivator binding 3/727 44/18639 0.0681818181818182 1.74806177316494 0.245402512365105 0.687282352668095 GO:0016248 channel inhibitor activity 3/727 44/18639 0.0681818181818182 1.74806177316494 0.245402512365105 0.687282352668095 GO:0030547 signaling receptor inhibitor activity 3/727 44/18639 0.0681818181818182 1.74806177316494 0.245402512365105 0.687282352668095 GO:0120013 lipid transfer activity 4/727 65/18639 0.0615384615384615 1.57773780552322 0.247755216946613 0.690484661946147 GO:0003774 cytoskeletal motor activity 8/727 153/18639 0.0522875816993464 1.3405615341047 0.248106353106073 0.690484661946147 GO:0003707 nuclear steroid receptor activity 2/727 25/18639 0.08 2.05105914718019 0.25483420992742 0.696074925264712 GO:0005537 D-mannose binding 2/727 25/18639 0.08 2.05105914718019 0.25483420992742 0.696074925264712 GO:0008139 nuclear localization sequence binding 2/727 25/18639 0.08 2.05105914718019 0.25483420992742 0.696074925264712 GO:0017025 TBP-class protein binding 2/727 25/18639 0.08 2.05105914718019 0.25483420992742 0.696074925264712 GO:0019211 phosphatase activator activity 2/727 25/18639 0.08 2.05105914718019 0.25483420992742 0.696074925264712 GO:0042974 nuclear retinoic acid receptor binding 2/727 25/18639 0.08 2.05105914718019 0.25483420992742 0.696074925264712 GO:0141110 transporter inhibitor activity 3/727 45/18639 0.0666666666666667 1.70921595598349 0.255968933522599 0.697023095899999 GO:0004197 cysteine-type endopeptidase activity 5/727 88/18639 0.0568181818181818 1.45671814430411 0.259419097143091 0.704251229974343 GO:0050840 extracellular matrix binding 4/727 67/18639 0.0597014925373134 1.53064115461208 0.264994508691326 0.711914268287229 GO:0030291 protein serine/threonine kinase inhibitor activity 3/727 46/18639 0.0652173913043478 1.67205908737516 0.266596252129749 0.711914268287229 GO:0003727 single-stranded RNA binding 5/727 89/18639 0.0561797752808989 1.44035052470519 0.266877058572318 0.711914268287229 GO:0005112 Notch binding 2/727 26/18639 0.0769230769230769 1.97217225690403 0.269481672176522 0.711914268287229 GO:0005160 transforming growth factor beta receptor binding 2/727 26/18639 0.0769230769230769 1.97217225690403 0.269481672176522 0.711914268287229 GO:0008143 poly(A) binding 2/727 26/18639 0.0769230769230769 1.97217225690403 0.269481672176522 0.711914268287229 GO:0019865 immunoglobulin binding 2/727 26/18639 0.0769230769230769 1.97217225690403 0.269481672176522 0.711914268287229 GO:0030247 polysaccharide binding 2/727 26/18639 0.0769230769230769 1.97217225690403 0.269481672176522 0.711914268287229 GO:0043548 phosphatidylinositol 3-kinase binding 2/727 26/18639 0.0769230769230769 1.97217225690403 0.269481672176522 0.711914268287229 GO:0001664 G protein-coupled receptor binding 14/727 297/18639 0.0471380471380471 1.20853653453378 0.271345353752568 0.714704279973281 GO:1990841 promoter-specific chromatin binding 4/727 68/18639 0.0588235294117647 1.50813172586779 0.273696461422496 0.718426361070345 GO:0019210 kinase inhibitor activity 5/727 90/18639 0.0555555555555556 1.42434662998624 0.274382045244945 0.718426361070345 GO:0140693 molecular condensate scaffold activity 3/727 48/18639 0.0625 1.60238995873453 0.287992025522113 0.744999682152294 GO:0061135 endopeptidase regulator activity 9/727 184/18639 0.0489130434782609 1.25404431553137 0.291424294368157 0.744999682152294 GO:0017124 SH3 domain binding 6/727 115/18639 0.0521739130434783 1.33764726990013 0.292506733299837 0.744999682152294 GO:0035401 histone H3Y41 kinase activity 6/727 115/18639 0.0521739130434783 1.33764726990013 0.292506733299837 0.744999682152294 GO:0140801 histone H2AXY142 kinase activity 6/727 115/18639 0.0521739130434783 1.33764726990013 0.292506733299837 0.744999682152294 GO:0008083 growth factor activity 8/727 162/18639 0.0493827160493827 1.26608589332111 0.298485916416363 0.744999682152294 GO:0045499 chemorepellent activity 2/727 28/18639 0.0714285714285714 1.83130280998231 0.298732542080159 0.744999682152294 GO:0046625 sphingolipid binding 2/727 28/18639 0.0714285714285714 1.83130280998231 0.298732542080159 0.744999682152294 GO:0050698 proteoglycan sulfotransferase activity 2/727 28/18639 0.0714285714285714 1.83130280998231 0.298732542080159 0.744999682152294 GO:0051537 2 iron, 2 sulfur cluster binding 2/727 28/18639 0.0714285714285714 1.83130280998231 0.298732542080159 0.744999682152294 GO:0035254 glutamate receptor binding 3/727 49/18639 0.0612244897959184 1.56968812284198 0.298740506820279 0.744999682152294 GO:0060590 ATPase regulator activity 3/727 49/18639 0.0612244897959184 1.56968812284198 0.298740506820279 0.744999682152294 GO:0070851 growth factor receptor binding 7/727 139/18639 0.0503597122302158 1.29113435523933 0.299488846925787 0.744999682152294 GO:0005125 cytokine activity 11/727 234/18639 0.047008547008547 1.20521637921913 0.30634120227355 0.744999682152294 GO:0042379 chemokine receptor binding 4/727 72/18639 0.0555555555555556 1.42434662998624 0.308920405409685 0.744999682152294 GO:0048020 CCR chemokine receptor binding 3/727 50/18639 0.06 1.53829436038514 0.309509950443342 0.744999682152294 GO:0140597 protein carrier chaperone 9/727 188/18639 0.0478723404255319 1.22736252158389 0.31288228539245 0.744999682152294 GO:0004629 phospholipase C activity 2/727 29/18639 0.0689655172413793 1.7681544372243 0.313294299746065 0.744999682152294 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/727 29/18639 0.0689655172413793 1.7681544372243 0.313294299746065 0.744999682152294 GO:0016417 S-acyltransferase activity 2/727 29/18639 0.0689655172413793 1.7681544372243 0.313294299746065 0.744999682152294 GO:0043236 laminin binding 2/727 29/18639 0.0689655172413793 1.7681544372243 0.313294299746065 0.744999682152294 GO:0097472 cyclin-dependent protein kinase activity 2/727 29/18639 0.0689655172413793 1.7681544372243 0.313294299746065 0.744999682152294 GO:0043539 protein serine/threonine kinase activator activity 4/727 73/18639 0.0547945205479452 1.4048350323152 0.3178029085924 0.744999682152294 GO:0004175 endopeptidase activity 18/727 405/18639 0.0444444444444444 1.139477303989 0.318277186432344 0.744999682152294 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/727 30/18639 0.0666666666666667 1.70921595598349 0.327788569416342 0.744999682152294 GO:0048019 receptor antagonist activity 2/727 30/18639 0.0666666666666667 1.70921595598349 0.327788569416342 0.744999682152294 GO:0070566 adenylyltransferase activity 2/727 30/18639 0.0666666666666667 1.70921595598349 0.327788569416342 0.744999682152294 GO:0000182 rDNA binding 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0003796 lysozyme activity 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0004090 carbonyl reductase (NADPH) activity 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0004382 GDP phosphatase activity 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0005381 iron ion transmembrane transporter activity 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0008140 cAMP response element binding protein binding 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0008239 dipeptidyl-peptidase activity 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0015643 toxic substance binding 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0035374 chondroitin sulfate binding 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0042975 peroxisome proliferator activated receptor binding 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0043422 protein kinase B binding 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0045322 unmethylated CpG binding 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0051880 G-quadruplex DNA binding 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0070097 delta-catenin binding 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0140135 mechanosensitive monoatomic cation channel activity 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0140940 histone H2A methyltransferase activity 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:1990259 histone H2AQ104 methyltransferase activity 1/727 10/18639 0.1 2.56382393397524 0.328304944677282 0.744999682152294 GO:0042626 ATPase-coupled transmembrane transporter activity 5/727 98/18639 0.0510204081632653 1.30807343570165 0.335680544698758 0.756618900942218 GO:0005544 calcium-dependent phospholipid binding 3/727 53/18639 0.0566037735849057 1.45122109470297 0.341854159279822 0.756618900942218 GO:0008146 sulfotransferase activity 3/727 53/18639 0.0566037735849057 1.45122109470297 0.341854159279822 0.756618900942218 GO:0140296 general transcription initiation factor binding 3/727 53/18639 0.0566037735849057 1.45122109470297 0.341854159279822 0.756618900942218 GO:0005164 tumor necrosis factor receptor binding 2/727 31/18639 0.0645161290322581 1.65407995740338 0.342198477791223 0.756618900942218 GO:0047499 calcium-independent phospholipase A2 activity 2/727 31/18639 0.0645161290322581 1.65407995740338 0.342198477791223 0.756618900942218 GO:0003724 RNA helicase activity 4/727 77/18639 0.051948051948052 1.33185658907805 0.353481613174563 0.756618900942218 GO:0051540 metal cluster binding 4/727 77/18639 0.051948051948052 1.33185658907805 0.353481613174563 0.756618900942218 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 12/727 268/18639 0.0447761194029851 1.14798086595906 0.353929809466926 0.756618900942218 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/727 11/18639 0.0909090909090909 2.33074903088658 0.354517962296028 0.756618900942218 GO:0008199 ferric iron binding 1/727 11/18639 0.0909090909090909 2.33074903088658 0.354517962296028 0.756618900942218 GO:0008432 JUN kinase binding 1/727 11/18639 0.0909090909090909 2.33074903088658 0.354517962296028 0.756618900942218 GO:0008503 benzodiazepine receptor activity 1/727 11/18639 0.0909090909090909 2.33074903088658 0.354517962296028 0.756618900942218 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/727 11/18639 0.0909090909090909 2.33074903088658 0.354517962296028 0.756618900942218 GO:0019107 myristoyltransferase activity 1/727 11/18639 0.0909090909090909 2.33074903088658 0.354517962296028 0.756618900942218 GO:0019215 intermediate filament binding 1/727 11/18639 0.0909090909090909 2.33074903088658 0.354517962296028 0.756618900942218 GO:0032794 GTPase activating protein binding 1/727 11/18639 0.0909090909090909 2.33074903088658 0.354517962296028 0.756618900942218 GO:0034056 estrogen response element binding 1/727 11/18639 0.0909090909090909 2.33074903088658 0.354517962296028 0.756618900942218 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/727 11/18639 0.0909090909090909 2.33074903088658 0.354517962296028 0.756618900942218 GO:0045294 alpha-catenin binding 1/727 11/18639 0.0909090909090909 2.33074903088658 0.354517962296028 0.756618900942218 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/727 11/18639 0.0909090909090909 2.33074903088658 0.354517962296028 0.756618900942218 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/727 11/18639 0.0909090909090909 2.33074903088658 0.354517962296028 0.756618900942218 GO:0140031 phosphorylation-dependent protein binding 1/727 11/18639 0.0909090909090909 2.33074903088658 0.354517962296028 0.756618900942218 GO:0140537 transcription regulator activator activity 1/727 11/18639 0.0909090909090909 2.33074903088658 0.354517962296028 0.756618900942218 GO:0043425 bHLH transcription factor binding 2/727 32/18639 0.0625 1.60238995873453 0.356508566884638 0.756618900942218 GO:0047498 calcium-dependent phospholipase A2 activity 2/727 32/18639 0.0625 1.60238995873453 0.356508566884638 0.756618900942218 GO:0070717 poly-purine tract binding 2/727 32/18639 0.0625 1.60238995873453 0.356508566884638 0.756618900942218 GO:0046982 protein heterodimerization activity 16/727 369/18639 0.043360433604336 1.11168517462341 0.368025848306276 0.765473320358502 GO:0071889 14-3-3 protein binding 2/727 33/18639 0.0606060606060606 1.55383268725772 0.370704709545812 0.765473320358502 GO:0008186 ATP-dependent activity, acting on RNA 4/727 79/18639 0.0506329113924051 1.29813870074696 0.371341113672898 0.765473320358502 GO:0033293 monocarboxylic acid binding 4/727 79/18639 0.0506329113924051 1.29813870074696 0.371341113672898 0.765473320358502 GO:0004721 phosphoprotein phosphatase activity 8/727 175/18639 0.0457142857142857 1.17203379838868 0.374645639072242 0.765473320358502 GO:0019783 ubiquitin-like protein peptidase activity 6/727 127/18639 0.047244094488189 1.21125540187807 0.375647279314699 0.765473320358502 GO:0016791 phosphatase activity 12/727 273/18639 0.043956043956044 1.12695557537373 0.37760342534998 0.765473320358502 GO:0016829 lyase activity 9/727 200/18639 0.045 1.15372077028886 0.378916795841781 0.765473320358502 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/727 12/18639 0.0833333333333333 2.13651994497937 0.379709364562014 0.765473320358502 GO:0004126 cytidine deaminase activity 1/727 12/18639 0.0833333333333333 2.13651994497937 0.379709364562014 0.765473320358502 GO:0004859 phospholipase inhibitor activity 1/727 12/18639 0.0833333333333333 2.13651994497937 0.379709364562014 0.765473320358502 GO:0005165 neurotrophin receptor binding 1/727 12/18639 0.0833333333333333 2.13651994497937 0.379709364562014 0.765473320358502 GO:0008179 adenylate cyclase binding 1/727 12/18639 0.0833333333333333 2.13651994497937 0.379709364562014 0.765473320358502 GO:0008603 cAMP-dependent protein kinase regulator activity 1/727 12/18639 0.0833333333333333 2.13651994497937 0.379709364562014 0.765473320358502 GO:0016208 AMP binding 1/727 12/18639 0.0833333333333333 2.13651994497937 0.379709364562014 0.765473320358502 GO:0016273 arginine N-methyltransferase activity 1/727 12/18639 0.0833333333333333 2.13651994497937 0.379709364562014 0.765473320358502 GO:0016274 protein-arginine N-methyltransferase activity 1/727 12/18639 0.0833333333333333 2.13651994497937 0.379709364562014 0.765473320358502 GO:0035197 siRNA binding 1/727 12/18639 0.0833333333333333 2.13651994497937 0.379709364562014 0.765473320358502 GO:0036009 protein-glutamine N-methyltransferase activity 1/727 12/18639 0.0833333333333333 2.13651994497937 0.379709364562014 0.765473320358502 GO:0070008 serine-type exopeptidase activity 1/727 12/18639 0.0833333333333333 2.13651994497937 0.379709364562014 0.765473320358502 GO:0070410 co-SMAD binding 1/727 12/18639 0.0833333333333333 2.13651994497937 0.379709364562014 0.765473320358502 GO:1990459 transferrin receptor binding 1/727 12/18639 0.0833333333333333 2.13651994497937 0.379709364562014 0.765473320358502 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 6/727 128/18639 0.046875 1.20179246905089 0.382651975928889 0.769652269766062 GO:0015020 glucuronosyltransferase activity 2/727 34/18639 0.0588235294117647 1.50813172586779 0.384774029403162 0.770418588284611 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/727 34/18639 0.0588235294117647 1.50813172586779 0.384774029403162 0.770418588284611 GO:0005506 iron ion binding 7/727 154/18639 0.0454545454545455 1.16537451544329 0.394743202470154 0.782768714567605 GO:0008408 3'-5' exonuclease activity 3/727 58/18639 0.0517241379310345 1.32611582791823 0.395391966314003 0.782768714567605 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 6/727 130/18639 0.0461538461538462 1.18330335414242 0.396661611041402 0.782768714567605 GO:0000175 3'-5'-RNA exonuclease activity 2/727 35/18639 0.0571428571428571 1.46504224798585 0.398704825014767 0.782768714567605 GO:0004623 phospholipase A2 activity 2/727 35/18639 0.0571428571428571 1.46504224798585 0.398704825014767 0.782768714567605 GO:0061631 ubiquitin conjugating enzyme activity 2/727 35/18639 0.0571428571428571 1.46504224798585 0.398704825014767 0.782768714567605 GO:0140566 histone reader activity 2/727 35/18639 0.0571428571428571 1.46504224798585 0.398704825014767 0.782768714567605 GO:0005262 calcium channel activity 6/727 131/18639 0.0458015267175573 1.1742705041108 0.403662140727574 0.782768714567605 GO:0005172 vascular endothelial growth factor receptor binding 1/727 13/18639 0.0769230769230769 1.97217225690403 0.403918914782845 0.782768714567605 GO:0019104 DNA N-glycosylase activity 1/727 13/18639 0.0769230769230769 1.97217225690403 0.403918914782845 0.782768714567605 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/727 13/18639 0.0769230769230769 1.97217225690403 0.403918914782845 0.782768714567605 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/727 13/18639 0.0769230769230769 1.97217225690403 0.403918914782845 0.782768714567605 GO:0071837 HMG box domain binding 1/727 13/18639 0.0769230769230769 1.97217225690403 0.403918914782845 0.782768714567605 GO:0140333 glycerophospholipid flippase activity 1/727 13/18639 0.0769230769230769 1.97217225690403 0.403918914782845 0.782768714567605 GO:0004879 nuclear receptor activity 3/727 59/18639 0.0508474576271186 1.30363928846199 0.405978350267266 0.782768714567605 GO:0031593 polyubiquitin modification-dependent protein binding 3/727 59/18639 0.0508474576271186 1.30363928846199 0.405978350267266 0.782768714567605 GO:0036002 pre-mRNA binding 3/727 59/18639 0.0508474576271186 1.30363928846199 0.405978350267266 0.782768714567605 GO:0005085 guanyl-nucleotide exchange factor activity 10/727 230/18639 0.0434782608695652 1.1147060582501 0.408614787954263 0.784353890302457 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/727 36/18639 0.0555555555555556 1.42434662998624 0.412486498019777 0.784353890302457 GO:0055106 ubiquitin-protein transferase regulator activity 2/727 36/18639 0.0555555555555556 1.42434662998624 0.412486498019777 0.784353890302457 GO:0004843 cysteine-type deubiquitinase activity 5/727 108/18639 0.0462962962962963 1.18695552498854 0.41349883203687 0.784353890302457 GO:0098531 ligand-modulated transcription factor activity 3/727 60/18639 0.05 1.28191196698762 0.416509196338592 0.784353890302457 GO:0031267 small GTPase binding 12/727 283/18639 0.0424028268551237 1.08713382359374 0.425366305110475 0.784353890302457 GO:0030551 cyclic nucleotide binding 2/727 37/18639 0.0540540540540541 1.38585077512175 0.426109485094685 0.784353890302457 GO:0043394 proteoglycan binding 2/727 37/18639 0.0540540540540541 1.38585077512175 0.426109485094685 0.784353890302457 GO:0015026 coreceptor activity 3/727 61/18639 0.0491803278688525 1.26089701670913 0.426978650539026 0.784353890302457 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 3/727 61/18639 0.0491803278688525 1.26089701670913 0.426978650539026 0.784353890302457 GO:0019905 syntaxin binding 3/727 61/18639 0.0491803278688525 1.26089701670913 0.426978650539026 0.784353890302457 GO:0005545 1-phosphatidylinositol binding 1/727 14/18639 0.0714285714285714 1.83130280998231 0.427184830650604 0.784353890302457 GO:0008474 palmitoyl-(protein) hydrolase activity 1/727 14/18639 0.0714285714285714 1.83130280998231 0.427184830650604 0.784353890302457 GO:0008494 translation activator activity 1/727 14/18639 0.0714285714285714 1.83130280998231 0.427184830650604 0.784353890302457 GO:0019992 diacylglycerol binding 1/727 14/18639 0.0714285714285714 1.83130280998231 0.427184830650604 0.784353890302457 GO:0031404 chloride ion binding 1/727 14/18639 0.0714285714285714 1.83130280998231 0.427184830650604 0.784353890302457 GO:0034236 protein kinase A catalytic subunit binding 1/727 14/18639 0.0714285714285714 1.83130280998231 0.427184830650604 0.784353890302457 GO:0046030 inositol trisphosphate phosphatase activity 1/727 14/18639 0.0714285714285714 1.83130280998231 0.427184830650604 0.784353890302457 GO:0061783 peptidoglycan muralytic activity 1/727 14/18639 0.0714285714285714 1.83130280998231 0.427184830650604 0.784353890302457 GO:0071933 Arp2/3 complex binding 1/727 14/18639 0.0714285714285714 1.83130280998231 0.427184830650604 0.784353890302457 GO:0098599 palmitoyl hydrolase activity 1/727 14/18639 0.0714285714285714 1.83130280998231 0.427184830650604 0.784353890302457 GO:1901612 cardiolipin binding 1/727 14/18639 0.0714285714285714 1.83130280998231 0.427184830650604 0.784353890302457 GO:1990825 sequence-specific mRNA binding 1/727 14/18639 0.0714285714285714 1.83130280998231 0.427184830650604 0.784353890302457 GO:0140789 histone phosphatase activity 6/727 136/18639 0.0441176470588235 1.13109879440084 0.438537112203967 0.802093188189604 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 2/727 38/18639 0.0526315789473684 1.34938101788171 0.439565193527636 0.802093188189604 GO:0042162 telomeric DNA binding 2/727 38/18639 0.0526315789473684 1.34938101788171 0.439565193527636 0.802093188189604 GO:0004559 alpha-mannosidase activity 1/727 15/18639 0.0666666666666667 1.70921595598349 0.449543844240779 0.803729903339574 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/727 15/18639 0.0666666666666667 1.70921595598349 0.449543844240779 0.803729903339574 GO:0005523 tropomyosin binding 1/727 15/18639 0.0666666666666667 1.70921595598349 0.449543844240779 0.803729903339574 GO:0017081 chloride channel regulator activity 1/727 15/18639 0.0666666666666667 1.70921595598349 0.449543844240779 0.803729903339574 GO:0033130 acetylcholine receptor binding 1/727 15/18639 0.0666666666666667 1.70921595598349 0.449543844240779 0.803729903339574 GO:0050700 CARD domain binding 1/727 15/18639 0.0666666666666667 1.70921595598349 0.449543844240779 0.803729903339574 GO:0050780 dopamine receptor binding 1/727 15/18639 0.0666666666666667 1.70921595598349 0.449543844240779 0.803729903339574 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/727 15/18639 0.0666666666666667 1.70921595598349 0.449543844240779 0.803729903339574 GO:0061578 K63-linked deubiquitinase activity 1/727 15/18639 0.0666666666666667 1.70921595598349 0.449543844240779 0.803729903339574 GO:0140776 protein-containing complex destabilizing activity 1/727 15/18639 0.0666666666666667 1.70921595598349 0.449543844240779 0.803729903339574 GO:0000217 DNA secondary structure binding 2/727 39/18639 0.0512820512820513 1.31478150460269 0.452845940232626 0.808001324810229 GO:0016887 ATP hydrolysis activity 17/727 417/18639 0.0407673860911271 1.04520400186041 0.461057446710615 0.813341481530863 GO:0004532 RNA exonuclease activity 2/727 40/18639 0.05 1.28191196698762 0.465944894033866 0.813341481530863 GO:0030331 nuclear estrogen receptor binding 2/727 40/18639 0.05 1.28191196698762 0.465944894033866 0.813341481530863 GO:0004713 protein tyrosine kinase activity 6/727 140/18639 0.0428571428571429 1.09878168598939 0.466163898217022 0.813341481530863 GO:0101005 deubiquitinase activity 5/727 115/18639 0.0434782608695652 1.1147060582501 0.467238161163721 0.813341481530863 GO:0038024 cargo receptor activity 3/727 65/18639 0.0461538461538462 1.18330335414242 0.468136143084024 0.813341481530863 GO:0000062 fatty-acyl-CoA binding 1/727 16/18639 0.0625 1.60238995873453 0.471031259685203 0.813341481530863 GO:0004708 MAP kinase kinase activity 1/727 16/18639 0.0625 1.60238995873453 0.471031259685203 0.813341481530863 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/727 16/18639 0.0625 1.60238995873453 0.471031259685203 0.813341481530863 GO:0008296 3'-5'-DNA exonuclease activity 1/727 16/18639 0.0625 1.60238995873453 0.471031259685203 0.813341481530863 GO:0015923 mannosidase activity 1/727 16/18639 0.0625 1.60238995873453 0.471031259685203 0.813341481530863 GO:0016722 oxidoreductase activity, acting on metal ions 1/727 16/18639 0.0625 1.60238995873453 0.471031259685203 0.813341481530863 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/727 16/18639 0.0625 1.60238995873453 0.471031259685203 0.813341481530863 GO:0097027 ubiquitin-protein transferase activator activity 1/727 16/18639 0.0625 1.60238995873453 0.471031259685203 0.813341481530863 GO:0140327 flippase activity 1/727 16/18639 0.0625 1.60238995873453 0.471031259685203 0.813341481530863 GO:0140328 floppase activity 1/727 16/18639 0.0625 1.60238995873453 0.471031259685203 0.813341481530863 GO:0005539 glycosaminoglycan binding 10/727 242/18639 0.0413223140495868 1.05943137767572 0.471715620893859 0.813341481530863 GO:0005543 phospholipid binding 20/727 497/18639 0.0402414486921529 1.03171989294778 0.475561077345603 0.813341481530863 GO:0016874 ligase activity 7/727 167/18639 0.0419161676646707 1.07465673879202 0.477580370393257 0.813341481530863 GO:0001530 lipopolysaccharide binding 2/727 41/18639 0.0487804878048781 1.25064582145134 0.478856021058525 0.813341481530863 GO:0140828 metal cation:monoatomic cation antiporter activity 2/727 41/18639 0.0487804878048781 1.25064582145134 0.478856021058525 0.813341481530863 GO:0043178 alcohol binding 4/727 92/18639 0.0434782608695652 1.1147060582501 0.485099645538473 0.813341481530863 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3/727 67/18639 0.0447761194029851 1.14798086595906 0.488216423226255 0.813341481530863 GO:0030414 peptidase inhibitor activity 7/727 169/18639 0.0414201183431953 1.06193890756371 0.49010567578122 0.813341481530863 GO:0008307 structural constituent of muscle 2/727 42/18639 0.0476190476190476 1.22086853998821 0.491574033083719 0.813341481530863 GO:0042056 chemoattractant activity 2/727 42/18639 0.0476190476190476 1.22086853998821 0.491574033083719 0.813341481530863 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/727 17/18639 0.0588235294117647 1.50813172586779 0.491681008609053 0.813341481530863 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/727 17/18639 0.0588235294117647 1.50813172586779 0.491681008609053 0.813341481530863 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/727 17/18639 0.0588235294117647 1.50813172586779 0.491681008609053 0.813341481530863 GO:0015278 intracellularly gated calcium channel activity 1/727 17/18639 0.0588235294117647 1.50813172586779 0.491681008609053 0.813341481530863 GO:0016018 cyclosporin A binding 1/727 17/18639 0.0588235294117647 1.50813172586779 0.491681008609053 0.813341481530863 GO:0030548 acetylcholine receptor regulator activity 1/727 17/18639 0.0588235294117647 1.50813172586779 0.491681008609053 0.813341481530863 GO:0031489 myosin V binding 1/727 17/18639 0.0588235294117647 1.50813172586779 0.491681008609053 0.813341481530863 GO:0032183 SUMO binding 1/727 17/18639 0.0588235294117647 1.50813172586779 0.491681008609053 0.813341481530863 GO:0036041 long-chain fatty acid binding 1/727 17/18639 0.0588235294117647 1.50813172586779 0.491681008609053 0.813341481530863 GO:0038191 neuropilin binding 1/727 17/18639 0.0588235294117647 1.50813172586779 0.491681008609053 0.813341481530863 GO:0046965 nuclear retinoid X receptor binding 1/727 17/18639 0.0588235294117647 1.50813172586779 0.491681008609053 0.813341481530863 GO:0070403 NAD+ binding 1/727 17/18639 0.0588235294117647 1.50813172586779 0.491681008609053 0.813341481530863 GO:1901567 fatty acid derivative binding 1/727 17/18639 0.0588235294117647 1.50813172586779 0.491681008609053 0.813341481530863 GO:0005548 phospholipid transporter activity 3/727 68/18639 0.0441176470588235 1.13109879440084 0.498117344540275 0.820919646030063 GO:0030145 manganese ion binding 3/727 68/18639 0.0441176470588235 1.13109879440084 0.498117344540275 0.820919646030063 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/727 43/18639 0.0465116279069767 1.19247624836058 0.504094338690836 0.824590614800288 GO:0048156 tau protein binding 2/727 43/18639 0.0465116279069767 1.19247624836058 0.504094338690836 0.824590614800288 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/727 18/18639 0.0555555555555556 1.42434662998624 0.511525703418483 0.824590614800288 GO:0004706 JUN kinase kinase kinase activity 1/727 18/18639 0.0555555555555556 1.42434662998624 0.511525703418483 0.824590614800288 GO:0017128 phospholipid scramblase activity 1/727 18/18639 0.0555555555555556 1.42434662998624 0.511525703418483 0.824590614800288 GO:0032393 MHC class I receptor activity 1/727 18/18639 0.0555555555555556 1.42434662998624 0.511525703418483 0.824590614800288 GO:0035615 clathrin adaptor activity 1/727 18/18639 0.0555555555555556 1.42434662998624 0.511525703418483 0.824590614800288 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/727 18/18639 0.0555555555555556 1.42434662998624 0.511525703418483 0.824590614800288 GO:0070628 proteasome binding 1/727 18/18639 0.0555555555555556 1.42434662998624 0.511525703418483 0.824590614800288 GO:0098641 cadherin binding involved in cell-cell adhesion 1/727 18/18639 0.0555555555555556 1.42434662998624 0.511525703418483 0.824590614800288 GO:0099602 neurotransmitter receptor regulator activity 1/727 18/18639 0.0555555555555556 1.42434662998624 0.511525703418483 0.824590614800288 GO:1901611 phosphatidylglycerol binding 1/727 18/18639 0.0555555555555556 1.42434662998624 0.511525703418483 0.824590614800288 GO:0015085 calcium ion transmembrane transporter activity 6/727 147/18639 0.0408163265306122 1.04645874856132 0.513553289202358 0.826353928989249 GO:0016782 transferase activity, transferring sulphur-containing groups 3/727 70/18639 0.0428571428571429 1.09878168598939 0.517622884265944 0.831390658031508 GO:0019209 kinase activator activity 6/727 148/18639 0.0405405405405405 1.03938808134131 0.520197685540867 0.834012593666063 GO:0140299 molecular sensor activity 3/727 71/18639 0.0422535211267606 1.08330588759517 0.527221109924544 0.835548166089099 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/727 45/18639 0.0444444444444444 1.139477303989 0.528526674462402 0.835548166089099 GO:0140303 intramembrane lipid transporter activity 2/727 45/18639 0.0444444444444444 1.139477303989 0.528526674462402 0.835548166089099 GO:0008301 DNA binding, bending 1/727 19/18639 0.0526315789473684 1.34938101788171 0.530596688522117 0.835548166089099 GO:0008381 mechanosensitive monoatomic ion channel activity 1/727 19/18639 0.0526315789473684 1.34938101788171 0.530596688522117 0.835548166089099 GO:0015245 fatty acid transmembrane transporter activity 1/727 19/18639 0.0526315789473684 1.34938101788171 0.530596688522117 0.835548166089099 GO:0022821 solute:potassium antiporter activity 1/727 19/18639 0.0526315789473684 1.34938101788171 0.530596688522117 0.835548166089099 GO:0034987 immunoglobulin receptor binding 1/727 19/18639 0.0526315789473684 1.34938101788171 0.530596688522117 0.835548166089099 GO:0043395 heparan sulfate proteoglycan binding 1/727 19/18639 0.0526315789473684 1.34938101788171 0.530596688522117 0.835548166089099 GO:0120227 acyl-CoA binding 1/727 19/18639 0.0526315789473684 1.34938101788171 0.530596688522117 0.835548166089099 GO:0000510 H3-H4 histone complex chaperone activity 6/727 151/18639 0.0397350993377483 1.01873798701003 0.539910576575921 0.841937295088835 GO:0140584 chromatin extrusion motor activity 6/727 151/18639 0.0397350993377483 1.01873798701003 0.539910576575921 0.841937295088835 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 6/727 151/18639 0.0397350993377483 1.01873798701003 0.539910576575921 0.841937295088835 GO:0140849 ATP-dependent H2AZ histone chaperone activity 6/727 151/18639 0.0397350993377483 1.01873798701003 0.539910576575921 0.841937295088835 GO:0003713 transcription coactivator activity 10/727 256/18639 0.0390625 1.00149372420908 0.543501653493031 0.841937295088835 GO:0005319 lipid transporter activity 7/727 178/18639 0.0393258426966292 1.00824536729363 0.545212562348898 0.841937295088835 GO:0015616 DNA translocase activity 6/727 152/18639 0.0394736842105263 1.01203576341128 0.546403716042067 0.841937295088835 GO:0140674 ATP-dependent histone chaperone activity 6/727 152/18639 0.0394736842105263 1.01203576341128 0.546403716042067 0.841937295088835 GO:0000339 RNA cap binding 1/727 20/18639 0.05 1.28191196698762 0.548924089566393 0.841937295088835 GO:0001614 purinergic nucleotide receptor activity 1/727 20/18639 0.05 1.28191196698762 0.548924089566393 0.841937295088835 GO:0001972 retinoic acid binding 1/727 20/18639 0.05 1.28191196698762 0.548924089566393 0.841937295088835 GO:0016502 nucleotide receptor activity 1/727 20/18639 0.05 1.28191196698762 0.548924089566393 0.841937295088835 GO:0030742 GTP-dependent protein binding 1/727 20/18639 0.05 1.28191196698762 0.548924089566393 0.841937295088835 GO:0052745 inositol phosphate phosphatase activity 1/727 20/18639 0.05 1.28191196698762 0.548924089566393 0.841937295088835 GO:0140939 histone H4 methyltransferase activity 1/727 20/18639 0.05 1.28191196698762 0.548924089566393 0.841937295088835 GO:0061775 cohesin loader activity 6/727 153/18639 0.0392156862745098 1.00542115057853 0.552855862262427 0.845950687324325 GO:0003684 damaged DNA binding 3/727 74/18639 0.0405405405405405 1.03938808134131 0.555364236537212 0.845950687324325 GO:0031491 nucleosome binding 3/727 74/18639 0.0405405405405405 1.03938808134131 0.555364236537212 0.845950687324325 GO:0048029 monosaccharide binding 3/727 74/18639 0.0405405405405405 1.03938808134131 0.555364236537212 0.845950687324325 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/727 21/18639 0.0476190476190476 1.22086853998821 0.56653686076169 0.849369361790897 GO:0010314 phosphatidylinositol-5-phosphate binding 1/727 21/18639 0.0476190476190476 1.22086853998821 0.56653686076169 0.849369361790897 GO:0051428 peptide hormone receptor binding 1/727 21/18639 0.0476190476190476 1.22086853998821 0.56653686076169 0.849369361790897 GO:0140312 cargo adaptor activity 1/727 21/18639 0.0476190476190476 1.22086853998821 0.56653686076169 0.849369361790897 GO:1904047 S-adenosyl-L-methionine binding 1/727 21/18639 0.0476190476190476 1.22086853998821 0.56653686076169 0.849369361790897 GO:0008238 exopeptidase activity 4/727 102/18639 0.0392156862745098 1.00542115057853 0.566650842043815 0.849369361790897 GO:0051536 iron-sulfur cluster binding 3/727 76/18639 0.0394736842105263 1.01203576341128 0.573560018737687 0.849369361790897 GO:0005004 GPI-linked ephrin receptor activity 2/727 49/18639 0.0408163265306122 1.04645874856132 0.574883895720618 0.849369361790897 GO:0005008 hepatocyte growth factor receptor activity 2/727 49/18639 0.0408163265306122 1.04645874856132 0.574883895720618 0.849369361790897 GO:0005009 insulin receptor activity 2/727 49/18639 0.0408163265306122 1.04645874856132 0.574883895720618 0.849369361790897 GO:0005011 macrophage colony-stimulating factor receptor activity 2/727 49/18639 0.0408163265306122 1.04645874856132 0.574883895720618 0.849369361790897 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/727 49/18639 0.0408163265306122 1.04645874856132 0.574883895720618 0.849369361790897 GO:0005020 stem cell factor receptor activity 2/727 49/18639 0.0408163265306122 1.04645874856132 0.574883895720618 0.849369361790897 GO:0008288 boss receptor activity 2/727 49/18639 0.0408163265306122 1.04645874856132 0.574883895720618 0.849369361790897 GO:0016763 pentosyltransferase activity 2/727 49/18639 0.0408163265306122 1.04645874856132 0.574883895720618 0.849369361790897 GO:0036332 placental growth factor receptor activity 2/727 49/18639 0.0408163265306122 1.04645874856132 0.574883895720618 0.849369361790897 GO:0038062 protein tyrosine kinase collagen receptor activity 2/727 49/18639 0.0408163265306122 1.04645874856132 0.574883895720618 0.849369361790897 GO:0060175 brain-derived neurotrophic factor receptor activity 2/727 49/18639 0.0408163265306122 1.04645874856132 0.574883895720618 0.849369361790897 GO:0008093 cytoskeletal anchor activity 1/727 22/18639 0.0454545454545455 1.16537451544329 0.583462830373155 0.851490824211571 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/727 22/18639 0.0454545454545455 1.16537451544329 0.583462830373155 0.851490824211571 GO:0031683 G-protein beta/gamma-subunit complex binding 1/727 22/18639 0.0454545454545455 1.16537451544329 0.583462830373155 0.851490824211571 GO:0033691 sialic acid binding 1/727 22/18639 0.0454545454545455 1.16537451544329 0.583462830373155 0.851490824211571 GO:0140658 ATP-dependent chromatin remodeler activity 6/727 158/18639 0.0379746835443038 0.973604025560218 0.58446196303628 0.851490824211571 GO:0005006 epidermal growth factor receptor activity 2/727 50/18639 0.04 1.0255295735901 0.585941143440505 0.851490824211571 GO:0005007 fibroblast growth factor receptor activity 2/727 50/18639 0.04 1.0255295735901 0.585941143440505 0.851490824211571 GO:0005017 platelet-derived growth factor receptor activity 2/727 50/18639 0.04 1.0255295735901 0.585941143440505 0.851490824211571 GO:0005019 platelet-derived growth factor beta-receptor activity 2/727 50/18639 0.04 1.0255295735901 0.585941143440505 0.851490824211571 GO:0032813 tumor necrosis factor receptor superfamily binding 2/727 50/18639 0.04 1.0255295735901 0.585941143440505 0.851490824211571 GO:0003689 DNA clamp loader activity 6/727 160/18639 0.0375 0.961433975240715 0.596779596080805 0.855025213786402 GO:0005010 insulin-like growth factor receptor activity 2/727 51/18639 0.0392156862745098 1.00542115057853 0.596783998347458 0.855025213786402 GO:0005021 vascular endothelial growth factor receptor activity 2/727 51/18639 0.0392156862745098 1.00542115057853 0.596783998347458 0.855025213786402 GO:0005030 neurotrophin receptor activity 2/727 51/18639 0.0392156862745098 1.00542115057853 0.596783998347458 0.855025213786402 GO:0000149 SNARE binding 4/727 106/18639 0.0377358490566038 0.967480729801978 0.597210111585052 0.855025213786402 GO:0003887 DNA-directed DNA polymerase activity 1/727 23/18639 0.0434782608695652 1.1147060582501 0.599728744447319 0.855025213786402 GO:0005212 structural constituent of eye lens 1/727 23/18639 0.0434782608695652 1.1147060582501 0.599728744447319 0.855025213786402 GO:0042171 lysophosphatidic acid acyltransferase activity 1/727 23/18639 0.0434782608695652 1.1147060582501 0.599728744447319 0.855025213786402 GO:0043274 phospholipase binding 1/727 23/18639 0.0434782608695652 1.1147060582501 0.599728744447319 0.855025213786402 GO:0070577 lysine-acetylated histone binding 1/727 23/18639 0.0434782608695652 1.1147060582501 0.599728744447319 0.855025213786402 GO:0071617 lysophospholipid acyltransferase activity 1/727 23/18639 0.0434782608695652 1.1147060582501 0.599728744447319 0.855025213786402 GO:0016835 carbon-oxygen lyase activity 3/727 79/18639 0.0379746835443038 0.973604025560218 0.599966844928085 0.855025213786402 GO:0004866 endopeptidase inhibitor activity 6/727 161/18639 0.0372670807453416 0.955462335642947 0.602865068069631 0.857774252800038 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/727 24/18639 0.0416666666666667 1.06825997248968 0.615360308842828 0.858361621526698 GO:0005315 phosphate transmembrane transporter activity 1/727 24/18639 0.0416666666666667 1.06825997248968 0.615360308842828 0.858361621526698 GO:0015295 solute:proton symporter activity 1/727 24/18639 0.0416666666666667 1.06825997248968 0.615360308842828 0.858361621526698 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/727 24/18639 0.0416666666666667 1.06825997248968 0.615360308842828 0.858361621526698 GO:0030215 semaphorin receptor binding 1/727 24/18639 0.0416666666666667 1.06825997248968 0.615360308842828 0.858361621526698 GO:0035035 histone acetyltransferase binding 1/727 24/18639 0.0416666666666667 1.06825997248968 0.615360308842828 0.858361621526698 GO:0070300 phosphatidic acid binding 1/727 24/18639 0.0416666666666667 1.06825997248968 0.615360308842828 0.858361621526698 GO:0140033 acetylation-dependent protein binding 1/727 24/18639 0.0416666666666667 1.06825997248968 0.615360308842828 0.858361621526698 GO:0016779 nucleotidyltransferase activity 5/727 136/18639 0.0367647058823529 0.942582328667368 0.616269516926458 0.858361621526698 GO:0019838 growth factor binding 5/727 136/18639 0.0367647058823529 0.942582328667368 0.616269516926458 0.858361621526698 GO:0005003 ephrin receptor activity 2/727 53/18639 0.0377358490566038 0.967480729801978 0.617826387471759 0.858361621526698 GO:0005005 transmembrane-ephrin receptor activity 2/727 53/18639 0.0377358490566038 0.967480729801978 0.617826387471759 0.858361621526698 GO:0017046 peptide hormone binding 2/727 53/18639 0.0377358490566038 0.967480729801978 0.617826387471759 0.858361621526698 GO:0038064 collagen receptor activity 2/727 53/18639 0.0377358490566038 0.967480729801978 0.617826387471759 0.858361621526698 GO:0051018 protein kinase A binding 2/727 53/18639 0.0377358490566038 0.967480729801978 0.617826387471759 0.858361621526698 GO:0004620 phospholipase activity 4/727 109/18639 0.036697247706422 0.940852819807428 0.619264533078224 0.859011146981548 GO:0140713 histone chaperone activity 6/727 164/18639 0.0365853658536585 0.937984366088503 0.620818292434682 0.859433965297133 GO:0140463 chromatin-protein adaptor activity 2/727 54/18639 0.037037037037037 0.94956441999083 0.628026662218956 0.859433965297133 GO:0004709 MAP kinase kinase kinase activity 1/727 25/18639 0.04 1.0255295735901 0.63038222963097 0.859433965297133 GO:0008483 transaminase activity 1/727 25/18639 0.04 1.0255295735901 0.63038222963097 0.859433965297133 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/727 25/18639 0.04 1.0255295735901 0.63038222963097 0.859433965297133 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/727 25/18639 0.04 1.0255295735901 0.63038222963097 0.859433965297133 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/727 25/18639 0.04 1.0255295735901 0.63038222963097 0.859433965297133 GO:0019707 protein-cysteine S-acyltransferase activity 1/727 25/18639 0.04 1.0255295735901 0.63038222963097 0.859433965297133 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/727 25/18639 0.04 1.0255295735901 0.63038222963097 0.859433965297133 GO:0030695 GTPase regulator activity 18/727 489/18639 0.0368098159509202 0.943738871401929 0.633835074928 0.859433965297133 GO:1901681 sulfur compound binding 10/727 275/18639 0.0363636363636364 0.932299612354633 0.634420597435017 0.859433965297133 GO:0030295 protein kinase activator activity 5/727 139/18639 0.0359712230215827 0.92223882517095 0.635481112128096 0.859433965297133 GO:0008236 serine-type peptidase activity 7/727 194/18639 0.0360824742268041 0.925091110197252 0.636232448411914 0.859433965297133 GO:0060589 nucleoside-triphosphatase regulator activity 18/727 490/18639 0.036734693877551 0.941812873705191 0.637259788515718 0.859433965297133 GO:0008017 microtubule binding 10/727 276/18639 0.036231884057971 0.928921715208421 0.638935459698252 0.859433965297133 GO:0004527 exonuclease activity 3/727 84/18639 0.0357142857142857 0.915651404991157 0.641528854245462 0.859433965297133 GO:0004435 phosphatidylinositol phospholipase C activity 1/727 26/18639 0.0384615384615385 0.986086128452016 0.644818251929148 0.859433965297133 GO:0004529 DNA exonuclease activity 1/727 26/18639 0.0384615384615385 0.986086128452016 0.644818251929148 0.859433965297133 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/727 26/18639 0.0384615384615385 0.986086128452016 0.644818251929148 0.859433965297133 GO:0008157 protein phosphatase 1 binding 1/727 26/18639 0.0384615384615385 0.986086128452016 0.644818251929148 0.859433965297133 GO:0030507 spectrin binding 1/727 26/18639 0.0384615384615385 0.986086128452016 0.644818251929148 0.859433965297133 GO:0050750 low-density lipoprotein particle receptor binding 1/727 26/18639 0.0384615384615385 0.986086128452016 0.644818251929148 0.859433965297133 GO:0051139 metal cation:proton antiporter activity 1/727 26/18639 0.0384615384615385 0.986086128452016 0.644818251929148 0.859433965297133 GO:0052742 phosphatidylinositol kinase activity 1/727 26/18639 0.0384615384615385 0.986086128452016 0.644818251929148 0.859433965297133 GO:0070006 metalloaminopeptidase activity 1/727 26/18639 0.0384615384615385 0.986086128452016 0.644818251929148 0.859433965297133 GO:0120014 phospholipid transfer activity 1/727 26/18639 0.0384615384615385 0.986086128452016 0.644818251929148 0.859433965297133 GO:0017171 serine hydrolase activity 7/727 198/18639 0.0353535353535354 0.906402400900338 0.657290457389508 0.872667229860448 GO:0005104 fibroblast growth factor receptor binding 1/727 27/18639 0.037037037037037 0.94956441999083 0.658691197227999 0.872667229860448 GO:0008266 poly(U) RNA binding 1/727 27/18639 0.037037037037037 0.94956441999083 0.658691197227999 0.872667229860448 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/727 27/18639 0.037037037037037 0.94956441999083 0.658691197227999 0.872667229860448 GO:0061980 regulatory RNA binding 2/727 58/18639 0.0344827586206897 0.884077218612152 0.666710035604468 0.881970674902772 GO:0019789 SUMO transferase activity 1/727 28/18639 0.0357142857142857 0.915651404991157 0.672022999270512 0.882404086579233 GO:0051019 mitogen-activated protein kinase binding 1/727 28/18639 0.0357142857142857 0.915651404991157 0.672022999270512 0.882404086579233 GO:0051393 alpha-actinin binding 1/727 28/18639 0.0357142857142857 0.915651404991157 0.672022999270512 0.882404086579233 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/727 28/18639 0.0357142857142857 0.915651404991157 0.672022999270512 0.882404086579233 GO:0097718 disordered domain specific binding 1/727 28/18639 0.0357142857142857 0.915651404991157 0.672022999270512 0.882404086579233 GO:0015459 potassium channel regulator activity 2/727 59/18639 0.0338983050847458 0.869092858974658 0.675858515791738 0.884786487017853 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/727 89/18639 0.0337078651685393 0.864210314823115 0.679956854097853 0.884786487017853 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/727 89/18639 0.0337078651685393 0.864210314823115 0.679956854097853 0.884786487017853 GO:0005261 monoatomic cation channel activity 12/727 341/18639 0.0351906158357771 0.902225431310935 0.683088876682445 0.884786487017853 GO:0001098 basal transcription machinery binding 2/727 60/18639 0.0333333333333333 0.854607977991747 0.684801595772881 0.884786487017853 GO:0001099 basal RNA polymerase II transcription machinery binding 2/727 60/18639 0.0333333333333333 0.854607977991747 0.684801595772881 0.884786487017853 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/727 60/18639 0.0333333333333333 0.854607977991747 0.684801595772881 0.884786487017853 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/727 60/18639 0.0333333333333333 0.854607977991747 0.684801595772881 0.884786487017853 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/727 29/18639 0.0344827586206897 0.884077218612152 0.684834738539242 0.884786487017853 GO:0099604 ligand-gated calcium channel activity 1/727 29/18639 0.0344827586206897 0.884077218612152 0.684834738539242 0.884786487017853 GO:0106222 lncRNA binding 1/727 29/18639 0.0344827586206897 0.884077218612152 0.684834738539242 0.884786487017853 GO:0140793 histone H2AXY142 phosphatase activity 3/727 90/18639 0.0333333333333333 0.854607977991747 0.687264353200925 0.886002263666922 GO:0004252 serine-type endopeptidase activity 6/727 176/18639 0.0340909090909091 0.874030886582468 0.687778028405848 0.886002263666922 GO:0016836 hydro-lyase activity 2/727 61/18639 0.0327868852459016 0.840598011139423 0.693541356628266 0.886458057088952 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/727 91/18639 0.032967032967033 0.845216681530299 0.694446224948547 0.886458057088952 GO:0001965 G-protein alpha-subunit binding 1/727 30/18639 0.0333333333333333 0.854607977991747 0.697146675405549 0.886458057088952 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/727 30/18639 0.0333333333333333 0.854607977991747 0.697146675405549 0.886458057088952 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/727 30/18639 0.0333333333333333 0.854607977991747 0.697146675405549 0.886458057088952 GO:0008187 poly-pyrimidine tract binding 1/727 30/18639 0.0333333333333333 0.854607977991747 0.697146675405549 0.886458057088952 GO:0016769 transferase activity, transferring nitrogenous groups 1/727 30/18639 0.0333333333333333 0.854607977991747 0.697146675405549 0.886458057088952 GO:0031624 ubiquitin conjugating enzyme binding 1/727 30/18639 0.0333333333333333 0.854607977991747 0.697146675405549 0.886458057088952 GO:0051721 protein phosphatase 2A binding 1/727 30/18639 0.0333333333333333 0.854607977991747 0.697146675405549 0.886458057088952 GO:0003697 single-stranded DNA binding 4/727 121/18639 0.0330578512396694 0.847545102140575 0.699589858867208 0.887015795268595 GO:0004540 RNA nuclease activity 4/727 121/18639 0.0330578512396694 0.847545102140575 0.699589858867208 0.887015795268595 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 17/727 484/18639 0.0351239669421488 0.900516671024362 0.705964939965228 0.892526002224087 GO:0016853 isomerase activity 6/727 180/18639 0.0333333333333333 0.854607977991747 0.708281593135771 0.892526002224087 GO:0016411 acylglycerol O-acyltransferase activity 1/727 31/18639 0.032258064516129 0.827039978701691 0.708978281992693 0.892526002224087 GO:0070273 phosphatidylinositol-4-phosphate binding 1/727 31/18639 0.032258064516129 0.827039978701691 0.708978281992693 0.892526002224087 GO:0070325 lipoprotein particle receptor binding 1/727 31/18639 0.032258064516129 0.827039978701691 0.708978281992693 0.892526002224087 GO:0016410 N-acyltransferase activity 3/727 94/18639 0.0319148936170213 0.818241681055928 0.715242359255194 0.898668851398368 GO:0008094 ATP-dependent activity, acting on DNA 7/727 210/18639 0.0333333333333333 0.854607977991747 0.715888746029208 0.898668851398368 GO:0004674 protein serine/threonine kinase activity 15/727 433/18639 0.0346420323325635 0.888160716157705 0.717659292413779 0.899475069349893 GO:0004536 DNA nuclease activity 2/727 64/18639 0.03125 0.801194979367263 0.718563699469349 0.899475069349893 GO:0008276 protein methyltransferase activity 3/727 95/18639 0.0315789473684211 0.809628610729023 0.721926453568505 0.902408066960631 GO:0001216 DNA-binding transcription activator activity 17/727 491/18639 0.0346232179226069 0.887678347812201 0.727408979968101 0.906800296869526 GO:0004386 helicase activity 5/727 155/18639 0.032258064516129 0.827039978701691 0.727489503703236 0.906800296869526 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/727 33/18639 0.0303030303030303 0.776916343628861 0.731274634154406 0.90895793711608 GO:0140416 transcription regulator inhibitor activity 1/727 33/18639 0.0303030303030303 0.776916343628861 0.731274634154406 0.90895793711608 GO:0005096 GTPase activator activity 9/727 271/18639 0.033210332103321 0.851454443017608 0.734545274077766 0.910891803785373 GO:0042826 histone deacetylase binding 4/727 127/18639 0.031496062992126 0.807503601252044 0.73488898068108 0.910891803785373 GO:0004725 protein tyrosine phosphatase activity 3/727 98/18639 0.0306122448979592 0.784844061420992 0.7412450258242 0.91092315902887 GO:0030332 cyclin binding 1/727 34/18639 0.0294117647058824 0.754065862933894 0.741774652480201 0.91092315902887 GO:0051427 hormone receptor binding 1/727 34/18639 0.0294117647058824 0.754065862933894 0.741774652480201 0.91092315902887 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/727 34/18639 0.0294117647058824 0.754065862933894 0.741774652480201 0.91092315902887 GO:0016500 protein-hormone receptor activity 2/727 67/18639 0.0298507462686567 0.765320577306042 0.741843886183461 0.91092315902887 GO:0042054 histone methyltransferase activity 2/727 67/18639 0.0298507462686567 0.765320577306042 0.741843886183461 0.91092315902887 GO:0016755 aminoacyltransferase activity 17/727 496/18639 0.0342741935483871 0.878729977370546 0.742119319389622 0.91092315902887 GO:0140223 general transcription initiation factor activity 2/727 68/18639 0.0294117647058824 0.754065862933894 0.749229538960527 0.914493757944753 GO:0016298 lipase activity 4/727 130/18639 0.0307692307692308 0.788868902761612 0.751327920228357 0.914493757944753 GO:0016798 hydrolase activity, acting on glycosyl bonds 4/727 130/18639 0.0307692307692308 0.788868902761612 0.751327920228357 0.914493757944753 GO:0005154 epidermal growth factor receptor binding 1/727 35/18639 0.0285714285714286 0.732521123992926 0.751864941523302 0.914493757944753 GO:0034061 DNA polymerase activity 1/727 35/18639 0.0285714285714286 0.732521123992926 0.751864941523302 0.914493757944753 GO:0106310 protein serine kinase activity 12/727 361/18639 0.0332409972299169 0.852240642872656 0.75427204014933 0.914493757944753 GO:0002039 p53 binding 2/727 69/18639 0.0289855072463768 0.743137372166736 0.756432790735079 0.914493757944753 GO:0016279 protein-lysine N-methyltransferase activity 2/727 69/18639 0.0289855072463768 0.743137372166736 0.756432790735079 0.914493757944753 GO:0000993 RNA polymerase II complex binding 1/727 36/18639 0.0277777777777778 0.712173314993122 0.761561468480546 0.914493757944753 GO:0004033 aldo-keto reductase (NADPH) activity 1/727 36/18639 0.0277777777777778 0.712173314993122 0.761561468480546 0.914493757944753 GO:0004190 aspartic-type endopeptidase activity 1/727 36/18639 0.0277777777777778 0.712173314993122 0.761561468480546 0.914493757944753 GO:0005484 SNAP receptor activity 1/727 36/18639 0.0277777777777778 0.712173314993122 0.761561468480546 0.914493757944753 GO:0016409 palmitoyltransferase activity 1/727 36/18639 0.0277777777777778 0.712173314993122 0.761561468480546 0.914493757944753 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/727 36/18639 0.0277777777777778 0.712173314993122 0.761561468480546 0.914493757944753 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/727 36/18639 0.0277777777777778 0.712173314993122 0.761561468480546 0.914493757944753 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/727 36/18639 0.0277777777777778 0.712173314993122 0.761561468480546 0.914493757944753 GO:0016278 lysine N-methyltransferase activity 2/727 70/18639 0.0285714285714286 0.732521123992926 0.763456611513582 0.915527237384174 GO:0140097 catalytic activity, acting on DNA 11/727 336/18639 0.0327380952380952 0.839347121241894 0.764796587766679 0.91589307195333 GO:0042805 actinin binding 1/727 37/18639 0.027027027027027 0.692925387560876 0.770879579130153 0.920686137017794 GO:0070001 aspartic-type peptidase activity 1/727 37/18639 0.027027027027027 0.692925387560876 0.770879579130153 0.920686137017794 GO:0019787 ubiquitin-like protein transferase activity 16/727 479/18639 0.0334029227557411 0.856392128258953 0.772310154294421 0.921151599124748 GO:0005501 retinoid binding 1/727 38/18639 0.0263157894736842 0.674690508940853 0.779834021984275 0.927625147118391 GO:0019840 isoprenoid binding 1/727 38/18639 0.0263157894736842 0.674690508940853 0.779834021984275 0.927625147118391 GO:0004497 monooxygenase activity 3/727 106/18639 0.0283018867924528 0.725610547351483 0.787551728764038 0.932845574573648 GO:0008013 beta-catenin binding 3/727 106/18639 0.0283018867924528 0.725610547351483 0.787551728764038 0.932845574573648 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/727 39/18639 0.0256410256410256 0.657390752301344 0.788438971504055 0.932845574573648 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/727 39/18639 0.0256410256410256 0.657390752301344 0.788438971504055 0.932845574573648 GO:0140767 enzyme-substrate adaptor activity 4/727 139/18639 0.0287769784172662 0.73779106013676 0.79594258732685 0.936370019410344 GO:0004177 aminopeptidase activity 1/727 40/18639 0.025 0.64095598349381 0.796708050413547 0.936370019410344 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/727 40/18639 0.025 0.64095598349381 0.796708050413547 0.936370019410344 GO:0032451 demethylase activity 1/727 40/18639 0.025 0.64095598349381 0.796708050413547 0.936370019410344 GO:0071949 FAD binding 1/727 40/18639 0.025 0.64095598349381 0.796708050413547 0.936370019410344 GO:0001727 lipid kinase activity 1/727 41/18639 0.024390243902439 0.625322910725668 0.804654351147423 0.939943675708305 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/727 41/18639 0.024390243902439 0.625322910725668 0.804654351147423 0.939943675708305 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/727 41/18639 0.024390243902439 0.625322910725668 0.804654351147423 0.939943675708305 GO:0042169 SH2 domain binding 1/727 41/18639 0.024390243902439 0.625322910725668 0.804654351147423 0.939943675708305 GO:0008201 heparin binding 5/727 172/18639 0.0290697674418605 0.745297655225361 0.805550691885703 0.939943675708305 GO:0020037 heme binding 4/727 142/18639 0.028169014084507 0.722203925063448 0.809302964471029 0.939943675708305 GO:0140030 modification-dependent protein binding 5/727 173/18639 0.0289017341040462 0.740989576293422 0.809531556316579 0.939943675708305 GO:0016859 cis-trans isomerase activity 1/727 42/18639 0.0238095238095238 0.610434269994105 0.81229045646605 0.939943675708305 GO:0019894 kinesin binding 1/727 42/18639 0.0238095238095238 0.610434269994105 0.81229045646605 0.939943675708305 GO:0035198 miRNA binding 1/727 42/18639 0.0238095238095238 0.610434269994105 0.81229045646605 0.939943675708305 GO:0043175 RNA polymerase core enzyme binding 1/727 42/18639 0.0238095238095238 0.610434269994105 0.81229045646605 0.939943675708305 GO:1902936 phosphatidylinositol bisphosphate binding 3/727 111/18639 0.027027027027027 0.692925387560876 0.812850679362199 0.939943675708305 GO:0019199 transmembrane receptor protein kinase activity 2/727 78/18639 0.0256410256410256 0.657390752301344 0.813555769031143 0.939943675708305 GO:0005245 voltage-gated calcium channel activity 1/727 43/18639 0.0232558139534884 0.596238124180289 0.819628459270221 0.944493732362169 GO:0008375 acetylglucosaminyltransferase activity 1/727 43/18639 0.0232558139534884 0.596238124180289 0.819628459270221 0.944493732362169 GO:0005516 calmodulin binding 6/727 207/18639 0.0289855072463768 0.743137372166736 0.822374954990936 0.946426313611155 GO:0000049 tRNA binding 2/727 80/18639 0.025 0.64095598349381 0.824502934869872 0.947642983584204 GO:0016790 thiolester hydrolase activity 1/727 44/18639 0.0227272727272727 0.582687257721646 0.826679981646568 0.948912819399757 GO:0004518 nuclease activity 6/727 209/18639 0.0287081339712919 0.736026009753658 0.829198803920862 0.950571167707206 GO:0046915 transition metal ion transmembrane transporter activity 1/727 45/18639 0.0222222222222222 0.569738651994498 0.833456193173481 0.95060297728498 GO:0051539 4 iron, 4 sulfur cluster binding 1/727 45/18639 0.0222222222222222 0.569738651994498 0.833456193173481 0.95060297728498 GO:0005216 monoatomic ion channel activity 14/727 448/18639 0.03125 0.801194979367263 0.836966660700406 0.95060297728498 GO:0004842 ubiquitin-protein transferase activity 14/727 449/18639 0.0311804008908686 0.799410580749518 0.83923523806654 0.95060297728498 GO:0005254 chloride channel activity 2/727 83/18639 0.0240963855421687 0.61778889975307 0.839842016800331 0.95060297728498 GO:0030165 PDZ domain binding 2/727 83/18639 0.0240963855421687 0.61778889975307 0.839842016800331 0.95060297728498 GO:0004180 carboxypeptidase activity 1/727 46/18639 0.0217391304347826 0.557353029125052 0.83996782851622 0.95060297728498 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/727 46/18639 0.0217391304347826 0.557353029125052 0.83996782851622 0.95060297728498 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/727 46/18639 0.0217391304347826 0.557353029125052 0.83996782851622 0.95060297728498 GO:0030276 clathrin binding 1/727 46/18639 0.0217391304347826 0.557353029125052 0.83996782851622 0.95060297728498 GO:0140938 histone H3 methyltransferase activity 1/727 47/18639 0.0212765957446809 0.545494454037285 0.846225204338772 0.956461437854167 GO:0046906 tetrapyrrole binding 4/727 152/18639 0.0263157894736842 0.674690508940853 0.848754039873525 0.957145734098576 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/727 48/18639 0.0208333333333333 0.534129986244842 0.852238235558958 0.957145734098576 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/727 48/18639 0.0208333333333333 0.534129986244842 0.852238235558958 0.957145734098576 GO:0032266 phosphatidylinositol-3-phosphate binding 1/727 48/18639 0.0208333333333333 0.534129986244842 0.852238235558958 0.957145734098576 GO:0038187 pattern recognition receptor activity 1/727 48/18639 0.0208333333333333 0.534129986244842 0.852238235558958 0.957145734098576 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/727 86/18639 0.0232558139534884 0.596238124180289 0.853956753576078 0.957860236900924 GO:0031406 carboxylic acid binding 5/727 187/18639 0.0267379679144385 0.685514420848995 0.858687254467143 0.961782511857562 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/727 122/18639 0.0245901639344262 0.630448508354567 0.859627081219583 0.961782511857562 GO:0061659 ubiquitin-like protein ligase activity 11/727 372/18639 0.0295698924731183 0.75811998047655 0.86331277024012 0.96468661826074 GO:0043177 organic acid binding 5/727 189/18639 0.0264550264550265 0.67826029999345 0.864762891350101 0.965088472692105 GO:0035091 phosphatidylinositol binding 8/727 284/18639 0.028169014084507 0.722203925063448 0.868713609739239 0.967271279237128 GO:0030544 Hsp70 protein binding 1/727 51/18639 0.0196078431372549 0.502710575289263 0.868904708467251 0.967271279237128 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/727 52/18639 0.0192307692307692 0.493043064226008 0.874032009787689 0.971756694299127 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/727 53/18639 0.0188679245283019 0.483740364900989 0.878959040986072 0.976008470856555 GO:0050661 NADP binding 1/727 54/18639 0.0185185185185185 0.474782209995415 0.883693614170358 0.97838233397425 GO:0051287 NAD binding 1/727 54/18639 0.0185185185185185 0.474782209995415 0.883693614170358 0.97838233397425 GO:0061630 ubiquitin protein ligase activity 10/727 353/18639 0.028328611898017 0.726295732004318 0.886306468701193 0.97838233397425 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 6/727 229/18639 0.0262008733624454 0.671744262176919 0.886454530050363 0.97838233397425 GO:0008374 O-acyltransferase activity 1/727 55/18639 0.0181818181818182 0.466149806177316 0.888243237118873 0.97838233397425 GO:0098632 cell-cell adhesion mediator activity 1/727 55/18639 0.0181818181818182 0.466149806177316 0.888243237118873 0.97838233397425 GO:0004867 serine-type endopeptidase inhibitor activity 2/727 95/18639 0.0210526315789474 0.539752407152682 0.88975000956411 0.97838233397425 GO:0030170 pyridoxal phosphate binding 1/727 56/18639 0.0178571428571429 0.457825702495579 0.892615125120088 0.97838233397425 GO:0170055 lipid transmembrane transporter activity 1/727 56/18639 0.0178571428571429 0.457825702495579 0.892615125120088 0.97838233397425 GO:0005179 hormone activity 3/727 132/18639 0.0227272727272727 0.582687257721646 0.892921409452691 0.97838233397425 GO:0140098 catalytic activity, acting on RNA 11/727 387/18639 0.0284237726098191 0.728735485109242 0.893257543334683 0.97838233397425 GO:0070279 vitamin B6 binding 1/727 57/18639 0.0175438596491228 0.449793672627235 0.89681621235238 0.981065943055447 GO:0008170 N-methyltransferase activity 2/727 98/18639 0.0204081632653061 0.523229374280661 0.899747533974199 0.983057490823662 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/727 60/18639 0.0166666666666667 0.427303988995873 0.908460021299322 0.991352797595438 GO:0005253 monoatomic anion channel activity 2/727 103/18639 0.0194174757281553 0.49782989009228 0.914552594313441 0.996772224097778 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/727 181/18639 0.0220994475138122 0.566590924635412 0.926269981253549 0.999210896311264 GO:0008235 metalloexopeptidase activity 1/727 66/18639 0.0151515151515152 0.38845817181443 0.927958327670129 0.999210896311264 GO:0008237 metallopeptidase activity 4/727 184/18639 0.0217391304347826 0.557353029125052 0.93178819874288 0.999210896311264 GO:0004222 metalloendopeptidase activity 2/727 110/18639 0.0181818181818182 0.466149806177316 0.931861042607039 0.999210896311264 GO:0003777 microtubule motor activity 1/727 68/18639 0.0147058823529412 0.377032931466947 0.933487925606793 0.999210896311264 GO:1901981 phosphatidylinositol phosphate binding 4/727 185/18639 0.0216216216216216 0.554340310048701 0.93354296027928 0.999210896311264 GO:0141003 histone H2AX kinase activity 9/727 354/18639 0.0254237288135593 0.651819644230993 0.93736598561489 0.999210896311264 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/727 70/18639 0.0142857142857143 0.366260561996463 0.938593635069571 0.999210896311264 GO:0140996 histone H3 kinase activity 9/727 357/18639 0.0252100840336134 0.646342168229052 0.940984568681138 0.999210896311264 GO:0035173 histone kinase activity 9/727 360/18639 0.025 0.64095598349381 0.944419099403204 0.999210896311264 GO:0003730 mRNA 3'-UTR binding 6/727 262/18639 0.0229007633587786 0.587135252055399 0.945416947008098 0.999210896311264 GO:0004521 RNA endonuclease activity 1/727 73/18639 0.0136986301369863 0.3512087580788 0.945527715874294 0.999210896311264 GO:0003678 DNA helicase activity 1/727 74/18639 0.0135135135135135 0.346462693780438 0.94766071978248 0.999210896311264 GO:0098631 cell adhesion mediator activity 1/727 76/18639 0.0131578947368421 0.337345254470426 0.95167974645755 0.999210896311264 GO:0015108 chloride transmembrane transporter activity 2/727 121/18639 0.0165289256198347 0.423772551070288 0.952521760789894 0.999210896311264 GO:0008528 G protein-coupled peptide receptor activity 2/727 122/18639 0.0163934426229508 0.420299005569712 0.954070005449399 0.999210896311264 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/727 122/18639 0.0163934426229508 0.420299005569712 0.954070005449399 0.999210896311264 GO:0015103 inorganic anion transmembrane transporter activity 3/727 165/18639 0.0181818181818182 0.466149806177316 0.958365772411155 0.999210896311264 GO:0001653 peptide receptor activity 2/727 128/18639 0.015625 0.400597489683631 0.96239267584814 0.999210896311264 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 5/727 243/18639 0.0205761316872428 0.527535788883794 0.962794193399271 0.999210896311264 GO:0004676 3-phosphoinositide-dependent protein kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0004711 ribosomal protein S6 kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0035175 histone H3S10 kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0035979 histone H2AXS139 kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0044022 histone H3S28 kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0044023 histone H4S1 kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0044024 histone H2AS1 kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0044025 histone H2BS14 kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0072354 histone H3T3 kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0072371 histone H2AS121 kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0072518 Rho-dependent protein serine/threonine kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0140823 histone H2BS36 kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0140855 histone H3S57 kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0140995 histone H2A kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0140997 histone H4 kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0140998 histone H2B kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:1990244 histone H2AT120 kinase activity 5/727 245/18639 0.0204081632653061 0.523229374280661 0.964649966767389 0.999210896311264 GO:0004677 DNA-dependent protein kinase activity 5/727 246/18639 0.0203252032520325 0.521102425604724 0.965545574905258 0.999210896311264 GO:0140857 histone H3T45 kinase activity 5/727 246/18639 0.0203252032520325 0.521102425604724 0.965545574905258 0.999210896311264 GO:0035402 histone H3T11 kinase activity 5/727 247/18639 0.0202429149797571 0.518992699185271 0.966420249129024 0.999210896311264 GO:0035403 histone H3T6 kinase activity 5/727 247/18639 0.0202429149797571 0.518992699185271 0.966420249129024 0.999210896311264 GO:0042393 histone binding 5/727 247/18639 0.0202429149797571 0.518992699185271 0.966420249129024 0.999210896311264 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/727 132/18639 0.0151515151515152 0.38845817181443 0.967115251785019 0.999210896311264 GO:0004679 AMP-activated protein kinase activity 5/727 248/18639 0.0201612903225806 0.516899986688557 0.967274419689602 0.999210896311264 GO:0050660 flavin adenine dinucleotide binding 1/727 86/18639 0.0116279069767442 0.298119062090144 0.96759744422458 0.999210896311264 GO:0015297 antiporter activity 2/727 135/18639 0.0148148148148148 0.379825767996332 0.970277220882132 0.999998164652667 GO:0051213 dioxygenase activity 1/727 93/18639 0.010752688172043 0.275679992900564 0.975507251817732 0.999998164652667 GO:0030594 neurotransmitter receptor activity 1/727 97/18639 0.0103092783505155 0.264311745770643 0.979127999628902 0.999998164652667 GO:0015293 symporter activity 2/727 146/18639 0.0136986301369863 0.3512087580788 0.979546858545992 0.999998164652667 GO:0008509 monoatomic anion transmembrane transporter activity 2/727 149/18639 0.0134228187919463 0.344137440802046 0.981543693217685 0.999998164652667 GO:0008168 methyltransferase activity 3/727 204/18639 0.0147058823529412 0.377032931466947 0.987379420680563 0.999998164652667 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/727 167/18639 0.0119760479041916 0.307044782512005 0.990098620659717 0.999998164652667 GO:0015294 solute:monoatomic cation symporter activity 1/727 116/18639 0.00862068965517241 0.221019304653038 0.990242102170892 0.999998164652667 GO:0016741 transferase activity, transferring one-carbon groups 3/727 215/18639 0.013953488372093 0.357742874508173 0.991091983259124 0.999998164652667 GO:0004519 endonuclease activity 1/727 127/18639 0.0078740157480315 0.201875900313011 0.993719049948131 0.999998164652667 GO:0099094 ligand-gated monoatomic cation channel activity 1/727 136/18639 0.00735294117647059 0.188516465733474 0.995620792168091 0.999998164652667 GO:0140101 catalytic activity, acting on a tRNA 1/727 139/18639 0.00719424460431655 0.18444776503419 0.996116991376766 0.999998164652667 GO:0022843 voltage-gated monoatomic cation channel activity 1/727 143/18639 0.00699300699300699 0.179288386991276 0.996692356897356 0.999998164652667 GO:0019842 vitamin binding 1/727 150/18639 0.00666666666666667 0.170921595598349 0.99750198720829 0.999998164652667 GO:0015079 potassium ion transmembrane transporter activity 1/727 160/18639 0.00625 0.160238995873453 0.998327616740406 0.999998164652667 GO:0015081 sodium ion transmembrane transporter activity 1/727 164/18639 0.00609756097560976 0.156330727681417 0.998575687351423 0.999998164652667 GO:0005244 voltage-gated monoatomic ion channel activity 1/727 173/18639 0.00578034682080925 0.148197915258684 0.999007671619534 0.999998164652667 GO:0022832 voltage-gated channel activity 1/727 175/18639 0.00571428571428571 0.146504224798585 0.999084270819935 0.999998164652667 GO:0015291 secondary active transmembrane transporter activity 3/727 287/18639 0.0104529616724739 0.267995533168144 0.999170920918315 0.999998164652667 GO:0015276 ligand-gated monoatomic ion channel activity 1/727 186/18639 0.00537634408602151 0.137839996450282 0.999411411017476 0.999998164652667 GO:0022834 ligand-gated channel activity 1/727 188/18639 0.00531914893617021 0.136373613509321 0.999456876380814 0.999998164652667 GO:0046943 carboxylic acid transmembrane transporter activity 1/727 188/18639 0.00531914893617021 0.136373613509321 0.999456876380814 0.999998164652667 GO:0005342 organic acid transmembrane transporter activity 1/727 189/18639 0.00529100529100529 0.13565205999869 0.999478276352152 0.999998164652667 GO:0046873 metal ion transmembrane transporter activity 6/727 450/18639 0.0133333333333333 0.341843191196699 0.999666873030098 0.999998164652667 GO:0022836 gated channel activity 3/727 318/18639 0.00943396226415094 0.241870182450494 0.999713261652723 0.999998164652667 GO:0045182 translation regulator activity 3/727 356/18639 0.00842696629213483 0.216052578705779 0.999923882310522 0.999998164652667 GO:0008514 organic anion transmembrane transporter activity 1/727 269/18639 0.00371747211895911 0.0953094399247301 0.999979219801297 0.999998164652667 GO:0030371 translation repressor activity 1/727 329/18639 0.00303951367781155 0.0779277791481836 0.999998164652667 0.999998164652667