ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0044389 ubiquitin-like protein ligase binding 41/799 322/18639 0.127329192546584 2.97032392975692 4.5034126874402e-10 4.56646046506436e-07 GO:0031625 ubiquitin protein ligase binding 38/799 302/18639 0.125827814569536 2.93529991960149 2.74951606142974e-09 1.39400464314488e-06 GO:0003725 double-stranded RNA binding 16/799 75/18639 0.213333333333333 4.97662077596996 8.94862050954847e-08 3.02463373222738e-05 GO:0046332 SMAD binding 16/799 79/18639 0.20253164556962 4.72463997718667 1.92272948872183e-07 4.87411925390984e-05 GO:0045296 cadherin binding 35/799 334/18639 0.104790419161677 2.44454145526219 1.06129470150879e-06 0.000184444107362323 GO:0023026 MHC class II protein complex binding 9/799 27/18639 0.333333333333333 7.77596996245307 1.09138525066464e-06 0.000184444107362323 GO:0042605 peptide antigen binding 11/799 45/18639 0.244444444444444 5.70237797246558 2.23663542207939e-06 0.000304864046762882 GO:0023023 MHC protein complex binding 10/799 37/18639 0.27027027027027 6.30484051009708 2.40523902771504e-06 0.000304864046762882 GO:0042277 peptide binding 28/799 249/18639 0.112449799196787 2.62321878251429 3.24781207459466e-06 0.000365920160404331 GO:0045309 protein phosphorylated amino acid binding 12/799 59/18639 0.203389830508475 4.74465963810696 6.19484876302743e-06 0.000628157664570982 GO:0003779 actin binding 40/799 443/18639 0.090293453724605 2.10635755190602 7.77340892076856e-06 0.000716566967787211 GO:0140313 molecular sequestering activity 11/799 55/18639 0.2 4.66558197747184 1.78260475672706e-05 0.00150630101943437 GO:0003712 transcription coregulator activity 42/799 495/18639 0.0848484848484849 1.97933780862442 2.09673685313715e-05 0.00163545474544698 GO:0032395 MHC class II receptor activity 5/799 10/18639 0.5 11.6639549436796 3.00928085670683e-05 0.00217957913478623 GO:0051015 actin filament binding 23/799 209/18639 0.110047846889952 2.56718625554671 3.38952371109227e-05 0.00220330411510277 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 7/799 23/18639 0.304347826086957 7.09979866137019 3.47661398832785e-05 0.00220330411510277 GO:0051219 phosphoprotein binding 14/799 93/18639 0.150537634408602 3.51172837014009 4.02747501750927e-05 0.00240227039279671 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 7/799 24/18639 0.291666666666667 6.80397371714643 4.72735372974987e-05 0.0025229140431402 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 7/799 24/18639 0.291666666666667 6.80397371714643 4.72735372974987e-05 0.0025229140431402 GO:0032182 ubiquitin-like protein binding 16/799 120/18639 0.133333333333333 3.11038798498123 5.37854007711297e-05 0.00272691981909627 GO:0140297 DNA-binding transcription factor binding 40/799 488/18639 0.0819672131147541 1.91212376125895 7.05622621783598e-05 0.00340714923089794 GO:0008081 phosphoric diester hydrolase activity 13/799 87/18639 0.149425287356322 3.48577963834103 8.14885464748962e-05 0.00367490553651796 GO:0004112 cyclic-nucleotide phosphodiesterase activity 7/799 26/18639 0.269230769230769 6.28059112351978 8.33558455028729e-05 0.00367490553651796 GO:0043015 gamma-tubulin binding 8/799 35/18639 0.228571428571429 5.33209368853924 9.24328443629449e-05 0.00390528767433442 GO:0003713 transcription coactivator activity 25/799 256/18639 0.09765625 2.27811619993742 0.000113535439574166 0.00441781680756998 GO:0001221 transcription coregulator binding 15/799 115/18639 0.130434782608696 3.04277085487294 0.000117500806162371 0.00441781680756998 GO:0031490 chromatin DNA binding 16/799 128/18639 0.125 2.9159887359199 0.000117634175349497 0.00441781680756998 GO:0140375 immune receptor activity 18/799 156/18639 0.115384615384615 2.69168191007991 0.00012889049627867 0.00466767725809182 GO:0001784 phosphotyrosine residue binding 9/799 47/18639 0.191489361702128 4.46704657417517 0.000146954286169179 0.00513833262674303 GO:0050321 tau-protein kinase activity 6/799 22/18639 0.272727272727273 6.36215724200705 0.000251786868786899 0.00851039616499719 GO:0005200 structural constituent of cytoskeleton 14/799 112/18639 0.125 2.9159887359199 0.000308063968202546 0.0100766730244317 GO:0043130 ubiquitin binding 13/799 100/18639 0.13 3.0326282853567 0.000339744347661612 0.0107656490165273 GO:0019956 chemokine binding 7/799 33/18639 0.212121212121212 4.94834452156104 0.000416707335308871 0.0124276834706822 GO:0140311 protein sequestering activity 7/799 33/18639 0.212121212121212 4.94834452156104 0.000416707335308871 0.0124276834706822 GO:0042578 phosphoric ester hydrolase activity 30/799 363/18639 0.0826446280991736 1.92792643697183 0.000478579371808071 0.0138651280860967 GO:0004674 protein serine/threonine kinase activity 34/799 433/18639 0.0785219399538106 1.83175273942312 0.000526819275045037 0.0144350762075048 GO:0019902 phosphatase binding 19/799 190/18639 0.1 2.33279098873592 0.000540786470860566 0.0144350762075048 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 29/799 349/18639 0.0830945558739255 1.93842231155707 0.000540959463397616 0.0144350762075048 GO:0004715 non-membrane spanning protein tyrosine kinase activity 8/799 45/18639 0.177777777777778 4.14718397997497 0.000579740315083138 0.0150732481921616 GO:0016504 peptidase activator activity 9/799 57/18639 0.157894736842105 3.68335419274093 0.000662017026601635 0.0165954576692702 GO:0070412 R-SMAD binding 6/799 26/18639 0.230769230769231 5.38336382015981 0.000671019491558261 0.0165954576692702 GO:0044325 transmembrane transporter binding 15/799 136/18639 0.110294117647059 2.57293123757638 0.000738710464594078 0.0178345812166285 GO:0004896 cytokine receptor activity 12/799 96/18639 0.125 2.9159887359199 0.000812042330309675 0.0191490912310235 GO:0048407 platelet-derived growth factor binding 4/799 11/18639 0.363636363636364 8.48287632267607 0.000868527325472817 0.020015607000669 GO:0106310 protein serine kinase activity 29/799 361/18639 0.0803324099722992 1.87398722086819 0.000924527728221727 0.0208326914759296 GO:0046875 ephrin receptor binding 6/799 28/18639 0.214285714285714 4.99883783300554 0.00102064881796532 0.0220199553492944 GO:0141052 histone H3 demethylase activity 6/799 28/18639 0.214285714285714 4.99883783300554 0.00102064881796532 0.0220199553492944 GO:0015631 tubulin binding 30/799 385/18639 0.0779220779220779 1.81775921200202 0.001233998500723 0.0260682183277734 GO:0019903 protein phosphatase binding 15/799 144/18639 0.104166666666667 2.42999061326658 0.0013303020344692 0.0269785252590354 GO:0019955 cytokine binding 15/799 144/18639 0.104166666666667 2.42999061326658 0.0013303020344692 0.0269785252590354 GO:0032451 demethylase activity 7/799 40/18639 0.175 4.08238423028786 0.00140163584564846 0.0278678185781871 GO:0032452 histone demethylase activity 6/799 30/18639 0.2 4.66558197747184 0.00149546087035189 0.0291614869718619 GO:0140996 histone H3 kinase activity 28/799 357/18639 0.0784313725490196 1.82963999116543 0.00160515313562902 0.0305827174896564 GO:0008137 NADH dehydrogenase (ubiquinone) activity 7/799 41/18639 0.170731707317073 3.98281388320767 0.00162866542844324 0.0305827174896564 GO:0019209 kinase activator activity 15/799 148/18639 0.101351351351351 2.36431519128641 0.00175091264363701 0.0322802043241324 GO:0140457 protein demethylase activity 6/799 31/18639 0.193548387096774 4.51507933303726 0.00178804198401811 0.0322802043241324 GO:0035173 histone kinase activity 28/799 360/18639 0.0777777777777778 1.81439299123905 0.00181456769869383 0.0322802043241324 GO:0003925 G protein activity 8/799 54/18639 0.148148148148148 3.45598664997914 0.00199416114241093 0.034863437903529 GO:0048156 tau protein binding 7/799 43/18639 0.162790697674419 3.79756672584917 0.00216769848230326 0.037255021373822 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 9/799 68/18639 0.132352941176471 3.08751748509166 0.00238693048695816 0.0403391252295929 GO:0003954 NADH dehydrogenase activity 7/799 44/18639 0.159090909090909 3.71125839117078 0.00248415135704464 0.0412939258367749 GO:0141003 histone H2AX kinase activity 27/799 354/18639 0.076271186440678 1.77924736429011 0.00284992966865701 0.0465168355070018 GO:0097110 scaffold protein binding 9/799 70/18639 0.128571428571429 2.99930269980333 0.002920099508714 0.0465168355070018 GO:0050699 WW domain binding 5/799 24/18639 0.208333333333333 4.85998122653317 0.00307881215320485 0.0465168355070018 GO:0019207 kinase regulator activity 23/799 287/18639 0.0801393728222996 1.86948406762809 0.00308031268716595 0.0465168355070018 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 4/799 15/18639 0.266666666666667 6.22077596996245 0.0031321737988875 0.0465168355070018 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 4/799 15/18639 0.266666666666667 6.22077596996245 0.0031321737988875 0.0465168355070018 GO:0061578 K63-linked deubiquitinase activity 4/799 15/18639 0.266666666666667 6.22077596996245 0.0031321737988875 0.0465168355070018 GO:0019783 ubiquitin-like protein peptidase activity 13/799 127/18639 0.102362204724409 2.38789628768244 0.00316534679485515 0.0465168355070018 GO:0035591 signaling adaptor activity 13/799 129/18639 0.10077519379845 2.35087463981139 0.00362488990197202 0.0518042159101635 GO:0008139 nuclear localization sequence binding 5/799 25/18639 0.2 4.66558197747184 0.00371466399050431 0.0518042159101635 GO:0008194 UDP-glycosyltransferase activity 14/799 145/18639 0.096551724137931 2.25234992015882 0.00382957015924962 0.0518042159101635 GO:0035401 histone H3Y41 kinase activity 12/799 115/18639 0.104347826086957 2.43421668389835 0.00383618180459414 0.0518042159101635 GO:0101005 deubiquitinase activity 12/799 115/18639 0.104347826086957 2.43421668389835 0.00383618180459414 0.0518042159101635 GO:0140801 histone H2AXY142 kinase activity 12/799 115/18639 0.104347826086957 2.43421668389835 0.00383618180459414 0.0518042159101635 GO:0043539 protein serine/threonine kinase activator activity 9/799 73/18639 0.123287671232877 2.87604368474291 0.00389139975303311 0.0518042159101635 GO:0044390 ubiquitin-like protein conjugating enzyme binding 6/799 36/18639 0.166666666666667 3.88798498122653 0.00394459943110097 0.0518042159101635 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 4/799 16/18639 0.25 5.8319774718398 0.0040360286557228 0.0518042159101635 GO:0070411 I-SMAD binding 4/799 16/18639 0.25 5.8319774718398 0.0040360286557228 0.0518042159101635 GO:1990782 protein tyrosine kinase binding 12/799 117/18639 0.102564102564103 2.39260614229325 0.00441327839696662 0.054896244264492 GO:0001637 G protein-coupled chemoattractant receptor activity 5/799 26/18639 0.192307692307692 4.48613651679985 0.00443934125215813 0.054896244264492 GO:0004950 chemokine receptor activity 5/799 26/18639 0.192307692307692 4.48613651679985 0.00443934125215813 0.054896244264492 GO:0001222 transcription corepressor binding 7/799 49/18639 0.142857142857143 3.33255855533703 0.00462988514062283 0.0565626931637536 GO:0003727 single-stranded RNA binding 10/799 89/18639 0.112359550561798 2.6211134704898 0.00473358746161107 0.0571411629294479 GO:0016757 glycosyltransferase activity 21/799 267/18639 0.0786516853932584 1.83477942934286 0.00563339826033379 0.0672031274820995 GO:0003697 single-stranded DNA binding 12/799 121/18639 0.0991735537190083 2.3135117243662 0.00577535531833483 0.0675659732967257 GO:0005048 signal sequence binding 7/799 51/18639 0.137254901960784 3.2018699845395 0.00579708054912735 0.0675659732967257 GO:0016922 nuclear receptor binding 13/799 137/18639 0.0948905109489051 2.21359728858153 0.0060328375102639 0.06951474131145 GO:0051019 mitogen-activated protein kinase binding 5/799 28/18639 0.178571428571429 4.16569819417129 0.00618067752907257 0.0704180563424673 GO:0070628 proteasome binding 4/799 18/18639 0.222222222222222 5.18397997496871 0.00633892081678879 0.0714185078691537 GO:0005080 protein kinase C binding 7/799 52/18639 0.134615384615385 3.14029556175989 0.00645698249338853 0.0719492334977579 GO:0004843 cysteine-type deubiquitinase activity 11/799 108/18639 0.101851851851852 2.37599082186066 0.00660759621186187 0.0728272017263906 GO:0030295 protein kinase activator activity 13/799 139/18639 0.0935251798561151 2.18174696788251 0.00679962720905494 0.0741378708600184 GO:0035250 UDP-galactosyltransferase activity 5/799 29/18639 0.172413793103448 4.02205342885503 0.00720982059349905 0.0769553482295583 GO:0106222 lncRNA binding 5/799 29/18639 0.172413793103448 4.02205342885503 0.00720982059349905 0.0769553482295583 GO:0031996 thioesterase binding 3/799 10/18639 0.3 6.99837296620776 0.00751053511958261 0.0785121918686264 GO:0045322 unmethylated CpG binding 3/799 10/18639 0.3 6.99837296620776 0.00751053511958261 0.0785121918686264 GO:0003823 antigen binding 15/799 174/18639 0.0862068965517241 2.01102671442752 0.00802070183439006 0.0829897108170563 GO:0005543 phospholipid binding 33/799 497/18639 0.0663983903420523 1.5489356665651 0.00880418819903785 0.0901762306446908 GO:0004725 protein tyrosine phosphatase activity 10/799 98/18639 0.102040816326531 2.38039896809788 0.00926125573619604 0.0934716877124548 GO:0051020 GTPase binding 23/799 315/18639 0.073015873015873 1.70330770606115 0.0093102963106094 0.0934716877124548 GO:0005178 integrin binding 14/799 161/18639 0.0869565217391304 2.02851390324863 0.00950275352147708 0.0943962946525973 GO:0008375 acetylglucosaminyltransferase activity 6/799 43/18639 0.13953488372093 3.255057193585 0.0095885782536662 0.0943962946525973 GO:0042608 T cell receptor binding 3/799 11/18639 0.272727272727273 6.36215724200705 0.0100012880423738 0.0965838673806383 GO:0070990 snRNP binding 3/799 11/18639 0.272727272727273 6.36215724200705 0.0100012880423738 0.0965838673806383 GO:0001223 transcription coactivator binding 6/799 44/18639 0.136363636363636 3.18107862100353 0.0107103298689222 0.101385682783579 GO:0016758 hexosyltransferase activity 16/799 197/18639 0.0812182741116751 1.894652579684 0.0108991933154165 0.101385682783579 GO:0008378 galactosyltransferase activity 5/799 32/18639 0.15625 3.64498591989987 0.0110027370258149 0.101385682783579 GO:0070717 poly-purine tract binding 5/799 32/18639 0.15625 3.64498591989987 0.0110027370258149 0.101385682783579 GO:0009055 electron transfer activity 11/799 116/18639 0.0948275862068965 2.21212938587027 0.0110899265799151 0.101385682783579 GO:0009931 calcium-dependent protein serine/threonine kinase activity 4/799 21/18639 0.19047619047619 4.44341140711604 0.011198418611204 0.101385682783579 GO:0051010 microtubule plus-end binding 4/799 21/18639 0.19047619047619 4.44341140711604 0.011198418611204 0.101385682783579 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 7/799 58/18639 0.120689655172414 2.81543740019852 0.0116459219942068 0.103893437436276 GO:0005518 collagen binding 8/799 72/18639 0.111111111111111 2.59198998748436 0.0117184254909884 0.103893437436276 GO:0019208 phosphatase regulator activity 11/799 117/18639 0.094017094017094 2.19322229710215 0.0117827862970135 0.103893437436276 GO:0001786 phosphatidylserine binding 7/799 59/18639 0.11864406779661 2.76771812222906 0.0127392951972987 0.107337211898595 GO:0070063 RNA polymerase binding 7/799 59/18639 0.11864406779661 2.76771812222906 0.0127392951972987 0.107337211898595 GO:0004722 protein serine/threonine phosphatase activity 10/799 103/18639 0.0970873786407767 2.26484562013196 0.012909522298369 0.107337211898595 GO:0010853 cyclase activator activity 3/799 12/18639 0.25 5.8319774718398 0.0129154564824242 0.107337211898595 GO:0035014 phosphatidylinositol 3-kinase regulator activity 3/799 12/18639 0.25 5.8319774718398 0.0129154564824242 0.107337211898595 GO:0035197 siRNA binding 3/799 12/18639 0.25 5.8319774718398 0.0129154564824242 0.107337211898595 GO:0070410 co-SMAD binding 3/799 12/18639 0.25 5.8319774718398 0.0129154564824242 0.107337211898595 GO:0016651 oxidoreductase activity, acting on NAD(P)H 9/799 88/18639 0.102272727272727 2.38580896575265 0.0130227290135256 0.107337211898595 GO:0061133 endopeptidase activator activity 4/799 22/18639 0.181818181818182 4.24143816133804 0.0132319048198465 0.107337211898595 GO:0070034 telomerase RNA binding 4/799 22/18639 0.181818181818182 4.24143816133804 0.0132319048198465 0.107337211898595 GO:0140789 histone phosphatase activity 12/799 136/18639 0.0882352941176471 2.05834499006111 0.0140612493136051 0.113159577809489 GO:0015026 coreceptor activity 7/799 61/18639 0.114754098360656 2.67697326576253 0.0151441130242146 0.120914414224832 GO:0016493 C-C chemokine receptor activity 4/799 23/18639 0.173913043478261 4.05702780649725 0.0154859211168625 0.122677531347645 GO:0140333 glycerophospholipid flippase activity 3/799 13/18639 0.230769230769231 5.38336382015981 0.0162630188889012 0.127834892661595 GO:0019888 protein phosphatase regulator activity 10/799 107/18639 0.0934579439252336 2.18017849414572 0.0165320029479126 0.128949622993718 GO:0004713 protein tyrosine kinase activity 12/799 140/18639 0.0857142857142857 1.99953513320222 0.0173370722542873 0.134196879891964 GO:0019957 C-C chemokine binding 4/799 24/18639 0.166666666666667 3.88798498122653 0.0179673429095941 0.138021861441882 GO:0004721 phosphoprotein phosphatase activity 14/799 175/18639 0.08 1.86623279098874 0.0186261375305311 0.142006792901944 GO:0140857 histone H3T45 kinase activity 18/799 246/18639 0.0731707317073171 1.70692023566043 0.0194517643849836 0.146768938176167 GO:0005161 platelet-derived growth factor receptor binding 3/799 14/18639 0.214285714285714 4.99883783300554 0.0200501565664258 0.146768938176167 GO:0042043 neurexin family protein binding 3/799 14/18639 0.214285714285714 4.99883783300554 0.0200501565664258 0.146768938176167 GO:0044548 S100 protein binding 3/799 14/18639 0.214285714285714 4.99883783300554 0.0200501565664258 0.146768938176167 GO:0071933 Arp2/3 complex binding 3/799 14/18639 0.214285714285714 4.99883783300554 0.0200501565664258 0.146768938176167 GO:0035403 histone H3T6 kinase activity 18/799 247/18639 0.0728744939271255 1.70000962741889 0.0201746228939216 0.146768938176167 GO:0043021 ribonucleoprotein complex binding 14/799 177/18639 0.0790960451977401 1.84514541481937 0.0203409003440079 0.146768938176167 GO:0035091 phosphatidylinositol binding 20/799 284/18639 0.0704225352112676 1.64281055544783 0.0207842717316476 0.146768938176167 GO:0000287 magnesium ion binding 17/799 230/18639 0.0739130434782609 1.72423681776133 0.0208115287435869 0.146768938176167 GO:0120013 lipid transfer activity 7/799 65/18639 0.107692307692308 2.51223644940791 0.0208909230435153 0.146768938176167 GO:0048306 calcium-dependent protein binding 8/799 80/18639 0.1 2.33279098873592 0.0211135539834436 0.146768938176167 GO:0005319 lipid transporter activity 14/799 178/18639 0.0786516853932584 1.83477942934286 0.0212416437918451 0.146768938176167 GO:0003743 translation initiation factor activity 6/799 51/18639 0.117647058823529 2.74445998674814 0.021265248695315 0.146768938176167 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 11/799 128/18639 0.0859375 2.00474225594493 0.0217526410158465 0.146768938176167 GO:0001618 virus receptor activity 8/799 81/18639 0.0987654320987654 2.30399109998609 0.0225798366424872 0.146768938176167 GO:0033192 calmodulin-dependent protein phosphatase activity 8/799 81/18639 0.0987654320987654 2.30399109998609 0.0225798366424872 0.146768938176167 GO:0140791 histone H2AXS140 phosphatase activity 8/799 81/18639 0.0987654320987654 2.30399109998609 0.0225798366424872 0.146768938176167 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 8/799 81/18639 0.0987654320987654 2.30399109998609 0.0225798366424872 0.146768938176167 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 8/799 81/18639 0.0987654320987654 2.30399109998609 0.0225798366424872 0.146768938176167 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 8/799 81/18639 0.0987654320987654 2.30399109998609 0.0225798366424872 0.146768938176167 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 8/799 81/18639 0.0987654320987654 2.30399109998609 0.0225798366424872 0.146768938176167 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 8/799 81/18639 0.0987654320987654 2.30399109998609 0.0225798366424872 0.146768938176167 GO:1990439 MAP kinase serine/threonine phosphatase activity 8/799 81/18639 0.0987654320987654 2.30399109998609 0.0225798366424872 0.146768938176167 GO:0005160 transforming growth factor beta receptor binding 4/799 26/18639 0.153846153846154 3.58890921343988 0.0236353748290961 0.149209499332889 GO:0008143 poly(A) binding 4/799 26/18639 0.153846153846154 3.58890921343988 0.0236353748290961 0.149209499332889 GO:0050681 nuclear androgen receptor binding 4/799 26/18639 0.153846153846154 3.58890921343988 0.0236353748290961 0.149209499332889 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 8/799 82/18639 0.0975609756097561 2.27589364754724 0.0241164122318457 0.149209499332889 GO:0033549 MAP kinase phosphatase activity 8/799 82/18639 0.0975609756097561 2.27589364754724 0.0241164122318457 0.149209499332889 GO:0140272 exogenous protein binding 8/799 82/18639 0.0975609756097561 2.27589364754724 0.0241164122318457 0.149209499332889 GO:0031386 protein tag activity 3/799 15/18639 0.2 4.66558197747184 0.0242796522583104 0.149209499332889 GO:0120283 protein serine/threonine kinase binding 3/799 15/18639 0.2 4.66558197747184 0.0242796522583104 0.149209499332889 GO:0141047 molecular tag activity 3/799 15/18639 0.2 4.66558197747184 0.0242796522583104 0.149209499332889 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 8/799 83/18639 0.0963855421686747 2.2484732421551 0.025724791285561 0.155613580811321 GO:0017124 SH3 domain binding 10/799 115/18639 0.0869565217391304 2.02851390324863 0.0259536464481496 0.155613580811321 GO:0005548 phospholipid transporter activity 7/799 68/18639 0.102941176470588 2.40140248840462 0.0260890618717204 0.155613580811321 GO:0032934 sterol binding 7/799 68/18639 0.102941176470588 2.40140248840462 0.0260890618717204 0.155613580811321 GO:1990841 promoter-specific chromatin binding 7/799 68/18639 0.102941176470588 2.40140248840462 0.0260890618717204 0.155613580811321 GO:0019887 protein kinase regulator activity 18/799 255/18639 0.0705882352941176 1.64667599204888 0.0267234426934312 0.158465326848768 GO:0017069 snRNA binding 6/799 54/18639 0.111111111111111 2.59198998748436 0.027405127250374 0.159713357357447 GO:0017018 myosin phosphatase activity 8/799 84/18639 0.0952380952380952 2.22170570355802 0.0274064341027572 0.159713357357447 GO:0051117 ATPase binding 8/799 84/18639 0.0952380952380952 2.22170570355802 0.0274064341027572 0.159713357357447 GO:0140327 flippase activity 3/799 16/18639 0.1875 4.37398310387985 0.0289512577050613 0.166798723368933 GO:0140328 floppase activity 3/799 16/18639 0.1875 4.37398310387985 0.0289512577050613 0.166798723368933 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/799 41/18639 0.121951219512195 2.84486705943405 0.0299186042893907 0.171398105929052 GO:0022853 active monoatomic ion transmembrane transporter activity 10/799 118/18639 0.0847457627118644 1.9769415158779 0.0303208644820554 0.17272672238654 GO:0008234 cysteine-type peptidase activity 14/799 187/18639 0.0748663101604278 1.74647453702154 0.0307475984845897 0.174151139872643 GO:0061630 ubiquitin protein ligase activity 23/799 353/18639 0.0651558073654391 1.5199488028591 0.0309933630198646 0.174151139872643 GO:0001217 DNA-binding transcription repressor activity 19/799 278/18639 0.0683453237410072 1.59435355345261 0.031086150213953 0.174151139872643 GO:0048487 beta-tubulin binding 5/799 42/18639 0.119047619047619 2.77713212944752 0.0328058336990837 0.17450097516829 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 17/799 243/18639 0.0699588477366255 1.63199369582348 0.0330124944707302 0.17450097516829 GO:0004629 phospholipase C activity 4/799 29/18639 0.137931034482759 3.21764274308403 0.0339630871212396 0.17450097516829 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 3/799 17/18639 0.176470588235294 4.11668998012221 0.0340620322648901 0.17450097516829 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 3/799 17/18639 0.176470588235294 4.11668998012221 0.0340620322648901 0.17450097516829 GO:0008429 phosphatidylethanolamine binding 3/799 17/18639 0.176470588235294 4.11668998012221 0.0340620322648901 0.17450097516829 GO:0032183 SUMO binding 3/799 17/18639 0.176470588235294 4.11668998012221 0.0340620322648901 0.17450097516829 GO:0004676 3-phosphoinositide-dependent protein kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0004711 ribosomal protein S6 kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0035175 histone H3S10 kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0035979 histone H2AXS139 kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0044022 histone H3S28 kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0044023 histone H4S1 kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0044024 histone H2AS1 kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0044025 histone H2BS14 kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0072354 histone H3T3 kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0072371 histone H2AS121 kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0072518 Rho-dependent protein serine/threonine kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0140823 histone H2BS36 kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0140855 histone H3S57 kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0140995 histone H2A kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0140997 histone H4 kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0140998 histone H2B kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:1990244 histone H2AT120 kinase activity 17/799 245/18639 0.0693877551020408 1.61867129830656 0.0352787967549304 0.17450097516829 GO:0031267 small GTPase binding 19/799 283/18639 0.0671378091872792 1.56618476275556 0.0362791997733589 0.178570442024102 GO:0004677 DNA-dependent protein kinase activity 17/799 246/18639 0.0691056910569106 1.61209133367929 0.036453729288944 0.178570442024102 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 8/799 89/18639 0.0898876404494382 2.09689077639184 0.036960856368124 0.179322049556353 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 8/799 89/18639 0.0898876404494382 2.09689077639184 0.036960856368124 0.179322049556353 GO:0061980 regulatory RNA binding 6/799 58/18639 0.103448275862069 2.41323205731302 0.0372650487112932 0.179936949491673 GO:0035402 histone H3T11 kinase activity 17/799 247/18639 0.0688259109311741 1.60556464811784 0.0376569675877064 0.180967607269831 GO:0031624 ubiquitin conjugating enzyme binding 4/799 30/18639 0.133333333333333 3.11038798498123 0.0379031478263336 0.181291471207086 GO:0004679 AMP-activated protein kinase activity 17/799 248/18639 0.0685483870967742 1.59909059711736 0.0388888436553592 0.182550671446698 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/799 44/18639 0.113636363636364 2.65089885083627 0.0390851467393823 0.182550671446698 GO:0043014 alpha-tubulin binding 5/799 44/18639 0.113636363636364 2.65089885083627 0.0390851467393823 0.182550671446698 GO:0140793 histone H2AXY142 phosphatase activity 8/799 90/18639 0.0888888888888889 2.07359198998748 0.0391095983648265 0.182550671446698 GO:0000400 four-way junction DNA binding 3/799 18/18639 0.166666666666667 3.88798498122653 0.0396066545545103 0.182550671446698 GO:0000900 mRNA regulatory element binding translation repressor activity 3/799 18/18639 0.166666666666667 3.88798498122653 0.0396066545545103 0.182550671446698 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 3/799 18/18639 0.166666666666667 3.88798498122653 0.0396066545545103 0.182550671446698 GO:1990381 ubiquitin-specific protease binding 3/799 18/18639 0.166666666666667 3.88798498122653 0.0396066545545103 0.182550671446698 GO:0140104 molecular carrier activity 17/799 249/18639 0.0682730923694779 1.59266854652653 0.0401496839013084 0.18421619672365 GO:0072341 modified amino acid binding 8/799 91/18639 0.0879120879120879 2.05080526482279 0.0413402011472774 0.188606377445958 GO:0019003 GDP binding 7/799 75/18639 0.0933333333333333 2.17727158948686 0.041478522850541 0.188606377445958 GO:0005496 steroid binding 9/799 108/18639 0.0833333333333333 1.94399249061327 0.0423555978173193 0.191445676426711 GO:0140303 intramembrane lipid transporter activity 5/799 45/18639 0.111111111111111 2.59198998748436 0.0424805495029684 0.191445676426711 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 6/799 60/18639 0.1 2.33279098873592 0.0429456586075448 0.192685388619692 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 3/799 19/18639 0.157894736842105 3.68335419274093 0.0455777089474829 0.201815706867894 GO:0070003 threonine-type peptidase activity 3/799 19/18639 0.157894736842105 3.68335419274093 0.0455777089474829 0.201815706867894 GO:1990380 K48-linked deubiquitinase activity 3/799 19/18639 0.157894736842105 3.68335419274093 0.0455777089474829 0.201815706867894 GO:0051213 dioxygenase activity 8/799 93/18639 0.0860215053763441 2.00670192579434 0.0460507948464427 0.203023939018665 GO:0120015 sterol transfer activity 4/799 32/18639 0.125 2.9159887359199 0.0465355701082004 0.203392534869462 GO:0140142 nucleocytoplasmic carrier activity 4/799 32/18639 0.125 2.9159887359199 0.0465355701082004 0.203392534869462 GO:0004842 ubiquitin-protein transferase activity 27/799 449/18639 0.0601336302895323 1.40279190859398 0.0488698519490815 0.212678239812741 GO:0061659 ubiquitin-like protein ligase activity 23/799 372/18639 0.0618279569892473 1.44231700916468 0.0508362632354836 0.220290474020429 GO:0010851 cyclase regulator activity 3/799 20/18639 0.15 3.49918648310388 0.0519659486533858 0.222335324618284 GO:0016004 phospholipase activator activity 3/799 20/18639 0.15 3.49918648310388 0.0519659486533858 0.222335324618284 GO:0061608 nuclear import signal receptor activity 3/799 20/18639 0.15 3.49918648310388 0.0519659486533858 0.222335324618284 GO:0008376 acetylgalactosaminyltransferase activity 4/799 34/18639 0.117647058823529 2.74445998674814 0.0561675796192062 0.238300944493201 GO:0030332 cyclin binding 4/799 34/18639 0.117647058823529 2.74445998674814 0.0561675796192062 0.238300944493201 GO:0001846 opsonin binding 3/799 21/18639 0.142857142857143 3.33255855533703 0.0587605369937493 0.246211506246536 GO:0035613 RNA stem-loop binding 3/799 21/18639 0.142857142857143 3.33255855533703 0.0587605369937493 0.246211506246536 GO:0072542 protein phosphatase activator activity 3/799 21/18639 0.142857142857143 3.33255855533703 0.0587605369937493 0.246211506246536 GO:0010485 histone H4 acetyltransferase activity 4/799 35/18639 0.114285714285714 2.66604684426962 0.0613544763152912 0.256022382648993 GO:0061775 cohesin loader activity 11/799 153/18639 0.0718954248366013 1.67716999190164 0.0650419447016087 0.260204506408886 GO:0008135 translation factor activity, RNA binding 7/799 83/18639 0.0843373493975904 1.96741408688572 0.0651244934520931 0.260204506408886 GO:0005031 tumor necrosis factor receptor activity 2/799 10/18639 0.2 4.66558197747184 0.065729150174384 0.260204506408886 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/799 10/18639 0.2 4.66558197747184 0.065729150174384 0.260204506408886 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/799 10/18639 0.2 4.66558197747184 0.065729150174384 0.260204506408886 GO:0030957 Tat protein binding 2/799 10/18639 0.2 4.66558197747184 0.065729150174384 0.260204506408886 GO:0035256 G protein-coupled glutamate receptor binding 2/799 10/18639 0.2 4.66558197747184 0.065729150174384 0.260204506408886 GO:0042975 peroxisome proliferator activated receptor binding 2/799 10/18639 0.2 4.66558197747184 0.065729150174384 0.260204506408886 GO:0050815 phosphoserine residue binding 2/799 10/18639 0.2 4.66558197747184 0.065729150174384 0.260204506408886 GO:0051864 histone H3K36 demethylase activity 2/799 10/18639 0.2 4.66558197747184 0.065729150174384 0.260204506408886 GO:0051880 G-quadruplex DNA binding 2/799 10/18639 0.2 4.66558197747184 0.065729150174384 0.260204506408886 GO:0070097 delta-catenin binding 2/799 10/18639 0.2 4.66558197747184 0.065729150174384 0.260204506408886 GO:0070513 death domain binding 2/799 10/18639 0.2 4.66558197747184 0.065729150174384 0.260204506408886 GO:0140517 protein-RNA adaptor activity 3/799 22/18639 0.136363636363636 3.18107862100353 0.0659492683896288 0.260204506408886 GO:0019838 growth factor binding 10/799 136/18639 0.0735294117647059 1.71528749171759 0.0676320982139116 0.265809874375606 GO:0180051 translation factor activity 7/799 84/18639 0.0833333333333333 1.94399249061327 0.0685534079383963 0.268390562353412 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 17/799 268/18639 0.0634328358208955 1.4797554779295 0.0699941583562607 0.272977217589417 GO:0030145 manganese ion binding 6/799 68/18639 0.0882352941176471 2.05834499006111 0.0708744277432307 0.275351225025425 GO:0005158 insulin receptor binding 3/799 23/18639 0.130434782608696 3.04277085487294 0.0735187704805438 0.283452597974416 GO:0031681 G-protein beta-subunit binding 3/799 23/18639 0.130434782608696 3.04277085487294 0.0735187704805438 0.283452597974416 GO:0140658 ATP-dependent chromatin remodeler activity 11/799 158/18639 0.069620253164557 1.62409499215792 0.0777998119335437 0.285944776933472 GO:0002162 dystroglycan binding 2/799 11/18639 0.181818181818182 4.24143816133804 0.0781131195370529 0.285944776933472 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 2/799 11/18639 0.181818181818182 4.24143816133804 0.0781131195370529 0.285944776933472 GO:0008526 phosphatidylinositol transfer activity 2/799 11/18639 0.181818181818182 4.24143816133804 0.0781131195370529 0.285944776933472 GO:0010854 adenylate cyclase regulator activity 2/799 11/18639 0.181818181818182 4.24143816133804 0.0781131195370529 0.285944776933472 GO:0019107 myristoyltransferase activity 2/799 11/18639 0.181818181818182 4.24143816133804 0.0781131195370529 0.285944776933472 GO:0034511 U3 snoRNA binding 2/799 11/18639 0.181818181818182 4.24143816133804 0.0781131195370529 0.285944776933472 GO:0034713 type I transforming growth factor beta receptor binding 2/799 11/18639 0.181818181818182 4.24143816133804 0.0781131195370529 0.285944776933472 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 2/799 11/18639 0.181818181818182 4.24143816133804 0.0781131195370529 0.285944776933472 GO:0048185 activin binding 2/799 11/18639 0.181818181818182 4.24143816133804 0.0781131195370529 0.285944776933472 GO:0050786 RAGE receptor binding 2/799 11/18639 0.181818181818182 4.24143816133804 0.0781131195370529 0.285944776933472 GO:0050998 nitric-oxide synthase binding 2/799 11/18639 0.181818181818182 4.24143816133804 0.0781131195370529 0.285944776933472 GO:0140031 phosphorylation-dependent protein binding 2/799 11/18639 0.181818181818182 4.24143816133804 0.0781131195370529 0.285944776933472 GO:0140537 transcription regulator activator activity 2/799 11/18639 0.181818181818182 4.24143816133804 0.0781131195370529 0.285944776933472 GO:0016791 phosphatase activity 17/799 273/18639 0.0622710622710623 1.45265372924947 0.0798268729637879 0.291167083400291 GO:0015485 cholesterol binding 5/799 54/18639 0.0925925925925926 2.15999165623696 0.0808083209403576 0.292641562262581 GO:0140463 chromatin-protein adaptor activity 5/799 54/18639 0.0925925925925926 2.15999165623696 0.0808083209403576 0.292641562262581 GO:0030552 cAMP binding 3/799 24/18639 0.125 2.9159887359199 0.0814546887049651 0.292890263641257 GO:0060229 lipase activator activity 3/799 24/18639 0.125 2.9159887359199 0.0814546887049651 0.292890263641257 GO:0016755 aminoacyltransferase activity 28/799 496/18639 0.0564516129032258 1.31689813880254 0.0844683469352481 0.30265337029096 GO:0004709 MAP kinase kinase kinase activity 3/799 25/18639 0.12 2.7993491864831 0.0897418545882537 0.307072389628074 GO:0019211 phosphatase activator activity 3/799 25/18639 0.12 2.7993491864831 0.0897418545882537 0.307072389628074 GO:0120020 cholesterol transfer activity 3/799 25/18639 0.12 2.7993491864831 0.0897418545882537 0.307072389628074 GO:0019787 ubiquitin-like protein transferase activity 27/799 479/18639 0.0563674321503132 1.31493437778434 0.0900909280907612 0.307072389628074 GO:0061791 GTPase motor activity 4/799 40/18639 0.1 2.33279098873592 0.0908720518971357 0.307072389628074 GO:1990606 membrane scission GTPase motor activity 4/799 40/18639 0.1 2.33279098873592 0.0908720518971357 0.307072389628074 GO:0000340 RNA 7-methylguanosine cap binding 2/799 12/18639 0.166666666666667 3.88798498122653 0.0911526521479787 0.307072389628074 GO:0005025 transforming growth factor beta receptor activity, type I 2/799 12/18639 0.166666666666667 3.88798498122653 0.0911526521479787 0.307072389628074 GO:0005026 transforming growth factor beta receptor activity, type II 2/799 12/18639 0.166666666666667 3.88798498122653 0.0911526521479787 0.307072389628074 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 2/799 12/18639 0.166666666666667 3.88798498122653 0.0911526521479787 0.307072389628074 GO:0015368 calcium:monoatomic cation antiporter activity 2/799 12/18639 0.166666666666667 3.88798498122653 0.0911526521479787 0.307072389628074 GO:0016361 activin receptor activity, type I 2/799 12/18639 0.166666666666667 3.88798498122653 0.0911526521479787 0.307072389628074 GO:0016362 activin receptor activity, type II 2/799 12/18639 0.166666666666667 3.88798498122653 0.0911526521479787 0.307072389628074 GO:0017002 activin receptor activity 2/799 12/18639 0.166666666666667 3.88798498122653 0.0911526521479787 0.307072389628074 GO:0035259 nuclear glucocorticoid receptor binding 2/799 12/18639 0.166666666666667 3.88798498122653 0.0911526521479787 0.307072389628074 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 2/799 12/18639 0.166666666666667 3.88798498122653 0.0911526521479787 0.307072389628074 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/799 12/18639 0.166666666666667 3.88798498122653 0.0911526521479787 0.307072389628074 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/799 12/18639 0.166666666666667 3.88798498122653 0.0911526521479787 0.307072389628074 GO:0042287 MHC protein binding 4/799 41/18639 0.0975609756097561 2.27589364754724 0.0974616138006757 0.323836172238087 GO:0140318 protein transporter activity 4/799 41/18639 0.0975609756097561 2.27589364754724 0.0974616138006757 0.323836172238087 GO:0004435 phosphatidylinositol phospholipase C activity 3/799 26/18639 0.115384615384615 2.69168191007991 0.0983644389046655 0.323836172238087 GO:0005112 Notch binding 3/799 26/18639 0.115384615384615 2.69168191007991 0.0983644389046655 0.323836172238087 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/799 26/18639 0.115384615384615 2.69168191007991 0.0983644389046655 0.323836172238087 GO:0030247 polysaccharide binding 3/799 26/18639 0.115384615384615 2.69168191007991 0.0983644389046655 0.323836172238087 GO:0097602 cullin family protein binding 3/799 26/18639 0.115384615384615 2.69168191007991 0.0983644389046655 0.323836172238087 GO:0015399 primary active transmembrane transporter activity 11/799 166/18639 0.0662650602409639 1.54582535398163 0.101271497404249 0.332327826433361 GO:0044183 protein folding chaperone 6/799 75/18639 0.08 1.86623279098874 0.102178803067267 0.334074573558594 GO:0004402 histone acetyltransferase activity 4/799 42/18639 0.0952380952380952 2.22170570355802 0.104267485390317 0.334074573558594 GO:0035198 miRNA binding 4/799 42/18639 0.0952380952380952 2.22170570355802 0.104267485390317 0.334074573558594 GO:0051879 Hsp90 protein binding 4/799 42/18639 0.0952380952380952 2.22170570355802 0.104267485390317 0.334074573558594 GO:0005035 death receptor activity 2/799 13/18639 0.153846153846154 3.58890921343988 0.104768949104175 0.334074573558594 GO:0019855 calcium channel inhibitor activity 2/799 13/18639 0.153846153846154 3.58890921343988 0.104768949104175 0.334074573558594 GO:0031432 titin binding 2/799 13/18639 0.153846153846154 3.58890921343988 0.104768949104175 0.334074573558594 GO:0070123 transforming growth factor beta receptor activity, type III 2/799 13/18639 0.153846153846154 3.58890921343988 0.104768949104175 0.334074573558594 GO:0140852 histone ubiquitin ligase activity 2/799 13/18639 0.153846153846154 3.58890921343988 0.104768949104175 0.334074573558594 GO:0008266 poly(U) RNA binding 3/799 27/18639 0.111111111111111 2.59198998748436 0.10730609080545 0.336957424128234 GO:0008320 protein transmembrane transporter activity 3/799 27/18639 0.111111111111111 2.59198998748436 0.10730609080545 0.336957424128234 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/799 27/18639 0.111111111111111 2.59198998748436 0.10730609080545 0.336957424128234 GO:0061134 peptidase regulator activity 14/799 226/18639 0.0619469026548673 1.44509176293376 0.107730145345374 0.336957424128234 GO:0004879 nuclear receptor activity 5/799 59/18639 0.0847457627118644 1.9769415158779 0.107999174400075 0.336957424128234 GO:0031593 polyubiquitin modification-dependent protein binding 5/799 59/18639 0.0847457627118644 1.9769415158779 0.107999174400075 0.336957424128234 GO:0070888 E-box binding 5/799 59/18639 0.0847457627118644 1.9769415158779 0.107999174400075 0.336957424128234 GO:0016410 N-acyltransferase activity 7/799 94/18639 0.074468085106383 1.7371847788459 0.108640441285926 0.337918427803463 GO:0140597 protein carrier chaperone 12/799 188/18639 0.0638297872340425 1.48901552472506 0.110355326888503 0.342202756773522 GO:0098531 ligand-modulated transcription factor activity 5/799 60/18639 0.0833333333333333 1.94399249061327 0.113913130381214 0.349429537189892 GO:0000510 H3-H4 histone complex chaperone activity 10/799 151/18639 0.0662251655629139 1.5448946945271 0.114699086983461 0.349429537189892 GO:0140584 chromatin extrusion motor activity 10/799 151/18639 0.0662251655629139 1.5448946945271 0.114699086983461 0.349429537189892 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 10/799 151/18639 0.0662251655629139 1.5448946945271 0.114699086983461 0.349429537189892 GO:0140849 ATP-dependent H2AZ histone chaperone activity 10/799 151/18639 0.0662251655629139 1.5448946945271 0.114699086983461 0.349429537189892 GO:0036408 histone H3K14 acetyltransferase activity 3/799 28/18639 0.107142857142857 2.49941891650277 0.116550063934911 0.349429537189892 GO:0046966 nuclear thyroid hormone receptor binding 3/799 28/18639 0.107142857142857 2.49941891650277 0.116550063934911 0.349429537189892 GO:0051537 2 iron, 2 sulfur cluster binding 3/799 28/18639 0.107142857142857 2.49941891650277 0.116550063934911 0.349429537189892 GO:0097718 disordered domain specific binding 3/799 28/18639 0.107142857142857 2.49941891650277 0.116550063934911 0.349429537189892 GO:0015616 DNA translocase activity 10/799 152/18639 0.0657894736842105 1.53473091364205 0.118363473307748 0.349429537189892 GO:0140674 ATP-dependent histone chaperone activity 10/799 152/18639 0.0657894736842105 1.53473091364205 0.118363473307748 0.349429537189892 GO:0005545 1-phosphatidylinositol binding 2/799 14/18639 0.142857142857143 3.33255855533703 0.118888747860466 0.349429537189892 GO:0008191 metalloendopeptidase inhibitor activity 2/799 14/18639 0.142857142857143 3.33255855533703 0.118888747860466 0.349429537189892 GO:0019992 diacylglycerol binding 2/799 14/18639 0.142857142857143 3.33255855533703 0.118888747860466 0.349429537189892 GO:0032454 histone H3K9 demethylase activity 2/799 14/18639 0.142857142857143 3.33255855533703 0.118888747860466 0.349429537189892 GO:0034236 protein kinase A catalytic subunit binding 2/799 14/18639 0.142857142857143 3.33255855533703 0.118888747860466 0.349429537189892 GO:0098821 BMP receptor activity 2/799 14/18639 0.142857142857143 3.33255855533703 0.118888747860466 0.349429537189892 GO:1990825 sequence-specific mRNA binding 2/799 14/18639 0.142857142857143 3.33255855533703 0.118888747860466 0.349429537189892 GO:0005085 guanyl-nucleotide exchange factor activity 14/799 230/18639 0.0608695652173913 1.41995973227404 0.11931260472688 0.349661795355655 GO:0003924 GTPase activity 19/799 331/18639 0.0574018126888218 1.33906431377591 0.121222299023869 0.354234614438626 GO:0140030 modification-dependent protein binding 11/799 173/18639 0.0635838150289017 1.48327750728873 0.124888585886763 0.363194434992044 GO:0003785 actin monomer binding 3/799 29/18639 0.103448275862069 2.41323205731302 0.126079330490335 0.363194434992044 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 3/799 29/18639 0.103448275862069 2.41323205731302 0.126079330490335 0.363194434992044 GO:0010484 histone H3 acetyltransferase activity 3/799 29/18639 0.103448275862069 2.41323205731302 0.126079330490335 0.363194434992044 GO:0097472 cyclin-dependent protein kinase activity 3/799 29/18639 0.103448275862069 2.41323205731302 0.126079330490335 0.363194434992044 GO:0004386 helicase activity 10/799 155/18639 0.0645161290322581 1.50502644434575 0.129741192905517 0.372684333162022 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/799 15/18639 0.133333333333333 3.11038798498123 0.133443993337721 0.373384709206893 GO:0005523 tropomyosin binding 2/799 15/18639 0.133333333333333 3.11038798498123 0.133443993337721 0.373384709206893 GO:0015929 hexosaminidase activity 2/799 15/18639 0.133333333333333 3.11038798498123 0.133443993337721 0.373384709206893 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/799 15/18639 0.133333333333333 3.11038798498123 0.133443993337721 0.373384709206893 GO:0042809 nuclear vitamin D receptor binding 2/799 15/18639 0.133333333333333 3.11038798498123 0.133443993337721 0.373384709206893 GO:0048531 beta-1,3-galactosyltransferase activity 2/799 15/18639 0.133333333333333 3.11038798498123 0.133443993337721 0.373384709206893 GO:0050780 dopamine receptor binding 2/799 15/18639 0.133333333333333 3.11038798498123 0.133443993337721 0.373384709206893 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/799 15/18639 0.133333333333333 3.11038798498123 0.133443993337721 0.373384709206893 GO:0030971 receptor tyrosine kinase binding 6/799 81/18639 0.0740740740740741 1.72799332498957 0.133870413074965 0.373384709206893 GO:0001968 fibronectin binding 3/799 30/18639 0.1 2.33279098873592 0.135876684119668 0.373384709206893 GO:0008187 poly-pyrimidine tract binding 3/799 30/18639 0.1 2.33279098873592 0.135876684119668 0.373384709206893 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/799 30/18639 0.1 2.33279098873592 0.135876684119668 0.373384709206893 GO:0043995 histone H4K5 acetyltransferase activity 3/799 30/18639 0.1 2.33279098873592 0.135876684119668 0.373384709206893 GO:0043996 histone H4K8 acetyltransferase activity 3/799 30/18639 0.1 2.33279098873592 0.135876684119668 0.373384709206893 GO:0043997 histone H4K12 acetyltransferase activity 3/799 30/18639 0.1 2.33279098873592 0.135876684119668 0.373384709206893 GO:0051721 protein phosphatase 2A binding 3/799 30/18639 0.1 2.33279098873592 0.135876684119668 0.373384709206893 GO:0061733 protein-lysine-acetyltransferase activity 4/799 47/18639 0.0851063829787234 1.98535403296674 0.141316783628716 0.386240481400317 GO:1990518 single-stranded 3'-5' DNA helicase activity 4/799 47/18639 0.0851063829787234 1.98535403296674 0.141316783628716 0.386240481400317 GO:0070851 growth factor receptor binding 9/799 139/18639 0.0647482014388489 1.51044020853405 0.143120213480585 0.390118001261594 GO:0001540 amyloid-beta binding 6/799 83/18639 0.072289156626506 1.68635493161633 0.145360227636006 0.391793563483132 GO:0047499 calcium-independent phospholipase A2 activity 3/799 31/18639 0.0967741935483871 2.25753966651863 0.145924832492536 0.391793563483132 GO:0004708 MAP kinase kinase activity 2/799 16/18639 0.125 2.9159887359199 0.148371526999529 0.391793563483132 GO:0005024 transforming growth factor beta receptor activity 2/799 16/18639 0.125 2.9159887359199 0.148371526999529 0.391793563483132 GO:0005159 insulin-like growth factor receptor binding 2/799 16/18639 0.125 2.9159887359199 0.148371526999529 0.391793563483132 GO:0005521 lamin binding 2/799 16/18639 0.125 2.9159887359199 0.148371526999529 0.391793563483132 GO:0008142 oxysterol binding 2/799 16/18639 0.125 2.9159887359199 0.148371526999529 0.391793563483132 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/799 16/18639 0.125 2.9159887359199 0.148371526999529 0.391793563483132 GO:0034450 ubiquitin-ubiquitin ligase activity 2/799 16/18639 0.125 2.9159887359199 0.148371526999529 0.391793563483132 GO:0043023 ribosomal large subunit binding 2/799 16/18639 0.125 2.9159887359199 0.148371526999529 0.391793563483132 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/799 16/18639 0.125 2.9159887359199 0.148371526999529 0.391793563483132 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/799 16/18639 0.125 2.9159887359199 0.148371526999529 0.391793563483132 GO:0043138 3'-5' DNA helicase activity 4/799 48/18639 0.0833333333333333 1.94399249061327 0.149281737891542 0.392154617155502 GO:0140693 molecular condensate scaffold activity 4/799 48/18639 0.0833333333333333 1.94399249061327 0.149281737891542 0.392154617155502 GO:0003689 DNA clamp loader activity 10/799 160/18639 0.0625 1.45799436795995 0.14995497732839 0.392905289434077 GO:0022884 macromolecule transmembrane transporter activity 3/799 32/18639 0.09375 2.18699155193992 0.156206480325398 0.40509813567763 GO:0030515 snoRNA binding 3/799 32/18639 0.09375 2.18699155193992 0.156206480325398 0.40509813567763 GO:0031369 translation initiation factor binding 3/799 32/18639 0.09375 2.18699155193992 0.156206480325398 0.40509813567763 GO:0047498 calcium-dependent phospholipase A2 activity 3/799 32/18639 0.09375 2.18699155193992 0.156206480325398 0.40509813567763 GO:0016763 pentosyltransferase activity 4/799 49/18639 0.0816326530612245 1.9043191744783 0.157414379911804 0.406153132902212 GO:0035254 glutamate receptor binding 4/799 49/18639 0.0816326530612245 1.9043191744783 0.157414379911804 0.406153132902212 GO:0050840 extracellular matrix binding 5/799 67/18639 0.0746268656716418 1.74088879756412 0.159353561814616 0.410112973807159 GO:0015278 intracellularly gated calcium channel activity 2/799 17/18639 0.117647058823529 2.74445998674814 0.163612792964148 0.417892624850494 GO:0036041 long-chain fatty acid binding 2/799 17/18639 0.117647058823529 2.74445998674814 0.163612792964148 0.417892624850494 GO:0051787 misfolded protein binding 2/799 17/18639 0.117647058823529 2.74445998674814 0.163612792964148 0.417892624850494 GO:0140713 histone chaperone activity 10/799 164/18639 0.0609756097560976 1.42243352971702 0.167205907458888 0.425996960209327 GO:0015078 proton transmembrane transporter activity 11/799 185/18639 0.0594594594594595 1.38706491222136 0.171767330732833 0.435430183407731 GO:1901981 phosphatidylinositol phosphate binding 11/799 185/18639 0.0594594594594595 1.38706491222136 0.171767330732833 0.435430183407731 GO:0002039 p53 binding 5/799 69/18639 0.072463768115942 1.69042825270719 0.173517757967544 0.437679120843507 GO:0008080 N-acetyltransferase activity 5/799 69/18639 0.072463768115942 1.69042825270719 0.173517757967544 0.437679120843507 GO:0015035 protein-disulfide reductase activity 3/799 34/18639 0.0882352941176471 2.05834499006111 0.177401515587374 0.44082803424531 GO:0052866 phosphatidylinositol phosphate phosphatase activity 3/799 34/18639 0.0882352941176471 2.05834499006111 0.177401515587374 0.44082803424531 GO:0042826 histone deacetylase binding 8/799 127/18639 0.062992125984252 1.46947463857381 0.178803863528911 0.44082803424531 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/799 18/18639 0.111111111111111 2.59198998748436 0.179113560265353 0.44082803424531 GO:0008525 phosphatidylcholine transporter activity 2/799 18/18639 0.111111111111111 2.59198998748436 0.179113560265353 0.44082803424531 GO:0017128 phospholipid scramblase activity 2/799 18/18639 0.111111111111111 2.59198998748436 0.179113560265353 0.44082803424531 GO:0031690 adrenergic receptor binding 2/799 18/18639 0.111111111111111 2.59198998748436 0.179113560265353 0.44082803424531 GO:0050811 GABA receptor binding 2/799 18/18639 0.111111111111111 2.59198998748436 0.179113560265353 0.44082803424531 GO:0070064 proline-rich region binding 2/799 18/18639 0.111111111111111 2.59198998748436 0.179113560265353 0.44082803424531 GO:1901611 phosphatidylglycerol binding 2/799 18/18639 0.111111111111111 2.59198998748436 0.179113560265353 0.44082803424531 GO:0030159 signaling receptor complex adaptor activity 4/799 52/18639 0.0769230769230769 1.79445460671994 0.182740146272628 0.448664669056767 GO:0004620 phospholipase activity 7/799 109/18639 0.0642201834862385 1.49812265331665 0.187130842582695 0.458334962267761 GO:0004623 phospholipase A2 activity 3/799 35/18639 0.0857142857142857 1.99953513320222 0.188280925519132 0.458934755952884 GO:0140566 histone reader activity 3/799 35/18639 0.0857142857142857 1.99953513320222 0.188280925519132 0.458934755952884 GO:0004864 protein phosphatase inhibitor activity 4/799 53/18639 0.0754716981132075 1.76059697263088 0.191464763863547 0.460781831074629 GO:0005246 calcium channel regulator activity 4/799 53/18639 0.0754716981132075 1.76059697263088 0.191464763863547 0.460781831074629 GO:0016860 intramolecular oxidoreductase activity 4/799 53/18639 0.0754716981132075 1.76059697263088 0.191464763863547 0.460781831074629 GO:0034212 protein N-acetyltransferase activity 4/799 53/18639 0.0754716981132075 1.76059697263088 0.191464763863547 0.460781831074629 GO:0140296 general transcription initiation factor binding 4/799 53/18639 0.0754716981132075 1.76059697263088 0.191464763863547 0.460781831074629 GO:0008094 ATP-dependent activity, acting on DNA 12/799 210/18639 0.0571428571428571 1.33302342213481 0.191765219638554 0.460781831074629 GO:0003756 protein disulfide isomerase activity 2/799 19/18639 0.105263157894737 2.45556946182728 0.194823660420396 0.461568204827761 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/799 19/18639 0.105263157894737 2.45556946182728 0.194823660420396 0.461568204827761 GO:0022821 solute:potassium antiporter activity 2/799 19/18639 0.105263157894737 2.45556946182728 0.194823660420396 0.461568204827761 GO:0030506 ankyrin binding 2/799 19/18639 0.105263157894737 2.45556946182728 0.194823660420396 0.461568204827761 GO:0046624 sphingolipid transporter activity 2/799 19/18639 0.105263157894737 2.45556946182728 0.194823660420396 0.461568204827761 GO:0140036 ubiquitin-modified protein reader activity 2/799 19/18639 0.105263157894737 2.45556946182728 0.194823660420396 0.461568204827761 GO:0005525 GTP binding 20/799 378/18639 0.0529100529100529 1.23428094642112 0.1956470873313 0.462438570055799 GO:0000993 RNA polymerase II complex binding 3/799 36/18639 0.0833333333333333 1.94399249061327 0.199325990155388 0.46894792115444 GO:0055106 ubiquitin-protein transferase regulator activity 3/799 36/18639 0.0833333333333333 1.94399249061327 0.199325990155388 0.46894792115444 GO:0005262 calcium channel activity 8/799 131/18639 0.0610687022900763 1.42460518396087 0.200442362182428 0.470482766789309 GO:0043178 alcohol binding 6/799 92/18639 0.0652173913043478 1.52138542743647 0.202094223422216 0.47326453244833 GO:0043022 ribosome binding 7/799 112/18639 0.0625 1.45799436795995 0.205089956646128 0.479173308846023 GO:0008017 microtubule binding 15/799 276/18639 0.0543478260869565 1.26782118953039 0.207243273570876 0.482033512660771 GO:0030695 GTPase regulator activity 25/799 489/18639 0.0511247443762781 1.19263342982409 0.208190887591461 0.482033512660771 GO:0030551 cyclic nucleotide binding 3/799 37/18639 0.0810810810810811 1.89145215302912 0.210520359145844 0.482033512660771 GO:0000339 RNA cap binding 2/799 20/18639 0.1 2.33279098873592 0.21069673950562 0.482033512660771 GO:0001614 purinergic nucleotide receptor activity 2/799 20/18639 0.1 2.33279098873592 0.21069673950562 0.482033512660771 GO:0016502 nucleotide receptor activity 2/799 20/18639 0.1 2.33279098873592 0.21069673950562 0.482033512660771 GO:0042288 MHC class I protein binding 2/799 20/18639 0.1 2.33279098873592 0.21069673950562 0.482033512660771 GO:0003678 DNA helicase activity 5/799 74/18639 0.0675675675675676 1.57621012752427 0.210864413115775 0.482033512660771 GO:0003684 damaged DNA binding 5/799 74/18639 0.0675675675675676 1.57621012752427 0.210864413115775 0.482033512660771 GO:0060589 nucleoside-triphosphatase regulator activity 25/799 490/18639 0.0510204081632653 1.19019948404894 0.211067928620693 0.482033512660771 GO:0042562 hormone binding 6/799 94/18639 0.0638297872340425 1.48901552472506 0.215680344172574 0.491460379755034 GO:0019212 phosphatase inhibitor activity 4/799 56/18639 0.0714285714285714 1.66627927766851 0.218373539384768 0.496481544699898 GO:0000146 microfilament motor activity 3/799 38/18639 0.0789473684210526 1.84167709637046 0.221848014493241 0.502129211375328 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 3/799 38/18639 0.0789473684210526 1.84167709637046 0.221848014493241 0.502129211375328 GO:0017022 myosin binding 5/799 76/18639 0.0657894736842105 1.53473091364205 0.226477546939343 0.510808187369513 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/799 21/18639 0.0952380952380952 2.22170570355802 0.226690023980553 0.510808187369513 GO:0002020 protease binding 8/799 136/18639 0.0588235294117647 1.37222999337407 0.228876704099549 0.514591968862402 GO:0000217 DNA secondary structure binding 3/799 39/18639 0.0769230769230769 1.79445460671994 0.233293304668046 0.522638634677708 GO:0003724 RNA helicase activity 5/799 77/18639 0.0649350649350649 1.51479934333501 0.23440910874907 0.522638634677708 GO:0017116 single-stranded DNA helicase activity 4/799 58/18639 0.0689655172413793 1.60882137154201 0.23684410814117 0.522638634677708 GO:0008093 cytoskeletal anchor activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0008970 phospholipase A1 activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0031683 G-protein beta/gamma-subunit complex binding 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0032931 histone H3K56 acetyltransferase activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0043992 histone H3K9 acetyltransferase activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0043993 histone H3K18 acetyltransferase activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0043994 histone H3K23 acetyltransferase activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0043999 histone H2AK5 acetyltransferase activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0044012 histone H2AK9 acetyltransferase activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0044014 histone H2BK5 acetyltransferase activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0044015 histone H2BK12 acetyltransferase activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0044016 histone H3K4 acetyltransferase activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0044017 histone H3K27 acetyltransferase activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0044018 histone H3K36 acetyltransferase activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0046972 histone H4K16 acetyltransferase activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0140035 ubiquitin-like protein reader activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0140908 histone H3K122 acetyltransferase activity 2/799 22/18639 0.0909090909090909 2.12071908066902 0.242764099539646 0.522638634677708 GO:0004532 RNA exonuclease activity 3/799 40/18639 0.075 1.74959324155194 0.244840973811634 0.524881072822403 GO:0015036 disulfide oxidoreductase activity 3/799 40/18639 0.075 1.74959324155194 0.244840973811634 0.524881072822403 GO:0015459 potassium channel regulator activity 4/799 59/18639 0.0677966101694915 1.58155321270232 0.246214648776886 0.525603481810027 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/799 59/18639 0.0677966101694915 1.58155321270232 0.246214648776886 0.525603481810027 GO:0004857 enzyme inhibitor activity 21/799 416/18639 0.0504807692307692 1.17761083565996 0.250305360046135 0.532504108640299 GO:0008186 ATP-dependent activity, acting on RNA 5/799 79/18639 0.0632911392405063 1.47644999287084 0.250497494892922 0.532504108640299 GO:0001098 basal transcription machinery binding 4/799 60/18639 0.0666666666666667 1.55519399249061 0.25566475723372 0.541219339947791 GO:0001099 basal RNA polymerase II transcription machinery binding 4/799 60/18639 0.0666666666666667 1.55519399249061 0.25566475723372 0.541219339947791 GO:0004602 glutathione peroxidase activity 2/799 23/18639 0.0869565217391304 2.02851390324863 0.258882702307179 0.542369958965867 GO:0043274 phospholipase binding 2/799 23/18639 0.0869565217391304 2.02851390324863 0.258882702307179 0.542369958965867 GO:0044013 histone H2B acetyltransferase activity 2/799 23/18639 0.0869565217391304 2.02851390324863 0.258882702307179 0.542369958965867 GO:0070577 lysine-acetylated histone binding 2/799 23/18639 0.0869565217391304 2.02851390324863 0.258882702307179 0.542369958965867 GO:0099186 structural constituent of postsynapse 2/799 23/18639 0.0869565217391304 2.02851390324863 0.258882702307179 0.542369958965867 GO:0003714 transcription corepressor activity 11/799 204/18639 0.053921568627451 1.25787749392623 0.26018305104213 0.54397033764272 GO:0051082 unfolded protein binding 7/799 121/18639 0.0578512396694215 1.34954850588028 0.262450043840178 0.547580955666544 GO:0043175 RNA polymerase core enzyme binding 3/799 42/18639 0.0714285714285714 1.66627927766851 0.268184548063597 0.558396574407572 GO:0019001 guanyl nucleotide binding 20/799 400/18639 0.05 1.16639549436796 0.270585200741709 0.561090784360108 GO:0032561 guanyl ribonucleotide binding 20/799 400/18639 0.05 1.16639549436796 0.270585200741709 0.561090784360108 GO:0005315 phosphate transmembrane transporter activity 2/799 24/18639 0.0833333333333333 1.94399249061327 0.275012521725562 0.564499386699839 GO:0043998 histone H2A acetyltransferase activity 2/799 24/18639 0.0833333333333333 1.94399249061327 0.275012521725562 0.564499386699839 GO:0050431 transforming growth factor beta binding 2/799 24/18639 0.0833333333333333 1.94399249061327 0.275012521725562 0.564499386699839 GO:0070300 phosphatidic acid binding 2/799 24/18639 0.0833333333333333 1.94399249061327 0.275012521725562 0.564499386699839 GO:0140033 acetylation-dependent protein binding 2/799 24/18639 0.0833333333333333 1.94399249061327 0.275012521725562 0.564499386699839 GO:0004712 protein serine/threonine/tyrosine kinase activity 3/799 43/18639 0.0697674418604651 1.6275285967925 0.279952121997486 0.572321475212603 GO:0008200 ion channel inhibitor activity 3/799 43/18639 0.0697674418604651 1.6275285967925 0.279952121997486 0.572321475212603 GO:0001848 complement binding 2/799 25/18639 0.08 1.86623279098874 0.291123014520111 0.584684108771905 GO:0003707 nuclear steroid receptor activity 2/799 25/18639 0.08 1.86623279098874 0.291123014520111 0.584684108771905 GO:0017025 TBP-class protein binding 2/799 25/18639 0.08 1.86623279098874 0.291123014520111 0.584684108771905 GO:0017056 structural constituent of nuclear pore 2/799 25/18639 0.08 1.86623279098874 0.291123014520111 0.584684108771905 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/799 25/18639 0.08 1.86623279098874 0.291123014520111 0.584684108771905 GO:0019707 protein-cysteine S-acyltransferase activity 2/799 25/18639 0.08 1.86623279098874 0.291123014520111 0.584684108771905 GO:0042974 nuclear retinoic acid receptor binding 2/799 25/18639 0.08 1.86623279098874 0.291123014520111 0.584684108771905 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/799 25/18639 0.08 1.86623279098874 0.291123014520111 0.584684108771905 GO:0001046 core promoter sequence-specific DNA binding 3/799 44/18639 0.0681818181818182 1.59053931050176 0.29176544283884 0.584684108771905 GO:0016248 channel inhibitor activity 3/799 44/18639 0.0681818181818182 1.59053931050176 0.29176544283884 0.584684108771905 GO:0016247 channel regulator activity 9/799 168/18639 0.0535714285714286 1.24970945825139 0.294647910494805 0.589295820989609 GO:0015085 calcium ion transmembrane transporter activity 8/799 147/18639 0.054421768707483 1.26954611631887 0.295786180227796 0.590407847935009 GO:0008013 beta-catenin binding 6/799 106/18639 0.0566037735849057 1.32044772947316 0.30257562677133 0.602773449010075 GO:0141110 transporter inhibitor activity 3/799 45/18639 0.0666666666666667 1.55519399249061 0.30361152677952 0.602918925234845 GO:0038024 cargo receptor activity 4/799 65/18639 0.0615384615384615 1.43556368537595 0.303837841020716 0.602918925234845 GO:0141108 transporter regulator activity 9/799 170/18639 0.0529411764705882 1.23500699403666 0.306444847702924 0.604828808471646 GO:0015145 monosaccharide transmembrane transporter activity 2/799 26/18639 0.0769230769230769 1.79445460671994 0.307186229154732 0.604828808471646 GO:0043548 phosphatidylinositol 3-kinase binding 2/799 26/18639 0.0769230769230769 1.79445460671994 0.307186229154732 0.604828808471646 GO:0120014 phospholipid transfer activity 2/799 26/18639 0.0769230769230769 1.79445460671994 0.307186229154732 0.604828808471646 GO:0016209 antioxidant activity 5/799 86/18639 0.0581395348837209 1.35627383066042 0.308654596391154 0.606542171977965 GO:0001671 ATPase activator activity 2/799 27/18639 0.0740740740740741 1.72799332498957 0.323176640222674 0.632307511082508 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/799 27/18639 0.0740740740740741 1.72799332498957 0.323176640222674 0.632307511082508 GO:0016298 lipase activity 7/799 130/18639 0.0538461538461538 1.25611822470396 0.323636684666491 0.632307511082508 GO:0004197 cysteine-type endopeptidase activity 5/799 88/18639 0.0568181818181818 1.32544942541814 0.325638893305809 0.633464569207804 GO:0005504 fatty acid binding 3/799 47/18639 0.0638297872340425 1.48901552472506 0.327352499275039 0.633464569207804 GO:0043495 protein-membrane adaptor activity 3/799 47/18639 0.0638297872340425 1.48901552472506 0.327352499275039 0.633464569207804 GO:0061749 forked DNA-dependent helicase activity 3/799 47/18639 0.0638297872340425 1.48901552472506 0.327352499275039 0.633464569207804 GO:0140938 histone H3 methyltransferase activity 3/799 47/18639 0.0638297872340425 1.48901552472506 0.327352499275039 0.633464569207804 GO:0031072 heat shock protein binding 7/799 131/18639 0.0534351145038168 1.24652953596576 0.330591202871236 0.633478919908481 GO:0003730 mRNA 3'-UTR binding 13/799 262/18639 0.049618320610687 1.1574917119682 0.334273573887921 0.633478919908481 GO:0016887 ATP hydrolysis activity 20/799 417/18639 0.0479616306954436 1.11884459891411 0.334691053054104 0.633478919908481 GO:0046625 sphingolipid binding 2/799 28/18639 0.0714285714285714 1.66627927766851 0.339070992244809 0.633478919908481 GO:0050698 proteoglycan sulfotransferase activity 2/799 28/18639 0.0714285714285714 1.66627927766851 0.339070992244809 0.633478919908481 GO:0051119 sugar transmembrane transporter activity 2/799 28/18639 0.0714285714285714 1.66627927766851 0.339070992244809 0.633478919908481 GO:0009378 four-way junction helicase activity 3/799 48/18639 0.0625 1.45799436795995 0.339223883367272 0.633478919908481 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/799 48/18639 0.0625 1.45799436795995 0.339223883367272 0.633478919908481 GO:0036121 double-stranded DNA helicase activity 3/799 48/18639 0.0625 1.45799436795995 0.339223883367272 0.633478919908481 GO:0060590 ATPase regulator activity 3/799 49/18639 0.0612244897959184 1.42823938085873 0.351081024896977 0.633478919908481 GO:0051087 protein-folding chaperone binding 7/799 134/18639 0.0522388059701493 1.21862215829488 0.351576401996174 0.633478919908481 GO:0016782 transferase activity, transferring sulphur-containing groups 4/799 70/18639 0.0571428571428571 1.33302342213481 0.352873570859854 0.633478919908481 GO:0001094 TFIID-class transcription factor complex binding 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0004935 adrenergic receptor activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0004955 prostaglandin receptor activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0005131 growth hormone receptor binding 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0005381 iron ion transmembrane transporter activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0008140 cAMP response element binding protein binding 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0016868 intramolecular phosphotransferase activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0031419 cobalamin binding 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0031434 mitogen-activated protein kinase kinase binding 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0043208 glycosphingolipid binding 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0043422 protein kinase B binding 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0047429 nucleoside triphosphate diphosphatase activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0050308 sugar-phosphatase activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0098505 G-rich strand telomeric DNA binding 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0140940 histone H2A methyltransferase activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0140999 histone H3K4 trimethyltransferase activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:1990259 histone H2AQ104 methyltransferase activity 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:1990763 arrestin family protein binding 1/799 10/18639 0.1 2.33279098873592 0.354828104130725 0.633478919908481 GO:0016417 S-acyltransferase activity 2/799 29/18639 0.0689655172413793 1.60882137154201 0.35484815237477 0.633478919908481 GO:0043236 laminin binding 2/799 29/18639 0.0689655172413793 1.60882137154201 0.35484815237477 0.633478919908481 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/799 29/18639 0.0689655172413793 1.60882137154201 0.35484815237477 0.633478919908481 GO:0051861 glycolipid binding 2/799 29/18639 0.0689655172413793 1.60882137154201 0.35484815237477 0.633478919908481 GO:0099604 ligand-gated calcium channel activity 2/799 29/18639 0.0689655172413793 1.60882137154201 0.35484815237477 0.633478919908481 GO:0140097 catalytic activity, acting on DNA 16/799 336/18639 0.0476190476190476 1.11085285177901 0.369077486896217 0.64750350087872 GO:0033218 amide binding 12/799 247/18639 0.048582995951417 1.13333975161259 0.37022928372016 0.64750350087872 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/799 30/18639 0.0666666666666667 1.55519399249061 0.370488971535849 0.64750350087872 GO:0031210 phosphatidylcholine binding 2/799 30/18639 0.0666666666666667 1.55519399249061 0.370488971535849 0.64750350087872 GO:0048019 receptor antagonist activity 2/799 30/18639 0.0666666666666667 1.55519399249061 0.370488971535849 0.64750350087872 GO:0070566 adenylyltransferase activity 2/799 30/18639 0.0666666666666667 1.55519399249061 0.370488971535849 0.64750350087872 GO:0098918 structural constituent of synapse 2/799 30/18639 0.0666666666666667 1.55519399249061 0.370488971535849 0.64750350087872 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 9/799 181/18639 0.0497237569060773 1.15995132036593 0.372882376797439 0.64750350087872 GO:0099106 ion channel regulator activity 8/799 160/18639 0.05 1.16639549436796 0.379636072901566 0.64750350087872 GO:0001851 complement component C3b binding 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0004016 adenylate cyclase activity 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0004954 prostanoid receptor activity 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0005114 type II transforming growth factor beta receptor binding 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0008172 S-methyltransferase activity 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0008432 JUN kinase binding 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0008503 benzodiazepine receptor activity 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0015173 aromatic amino acid transmembrane transporter activity 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0019203 carbohydrate phosphatase activity 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0019215 intermediate filament binding 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0032050 clathrin heavy chain binding 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0032794 GTPase activating protein binding 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0034056 estrogen response element binding 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0035252 UDP-xylosyltransferase activity 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0042285 xylosyltransferase activity 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0045294 alpha-catenin binding 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0180030 inositol phosphate kinase activity 1/799 11/18639 0.0909090909090909 2.12071908066902 0.382499602590092 0.64750350087872 GO:0008327 methyl-CpG binding 2/799 31/18639 0.0645161290322581 1.50502644434575 0.385976153538837 0.651038443704608 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 11/799 229/18639 0.0480349344978166 1.12055462341027 0.39331563317313 0.651038443704608 GO:0016407 acetyltransferase activity 5/799 96/18639 0.0520833333333333 1.21499530663329 0.394169691419929 0.651038443704608 GO:0005516 calmodulin binding 10/799 207/18639 0.0483091787439614 1.12695216847146 0.395409385505845 0.651038443704608 GO:0005544 calcium-dependent phospholipid binding 3/799 53/18639 0.0566037735849057 1.32044772947316 0.398164326493736 0.651038443704608 GO:0051018 protein kinase A binding 3/799 53/18639 0.0566037735849057 1.32044772947316 0.398164326493736 0.651038443704608 GO:0043425 bHLH transcription factor binding 2/799 32/18639 0.0625 1.45799436795995 0.401294131753066 0.651038443704608 GO:0051059 NF-kappaB binding 2/799 32/18639 0.0625 1.45799436795995 0.401294131753066 0.651038443704608 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0004000 adenosine deaminase activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0004126 cytidine deaminase activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0004859 phospholipase inhibitor activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0005049 nuclear export signal receptor activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0005078 MAP-kinase scaffold activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0005095 GTPase inhibitor activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0005165 neurotrophin receptor binding 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0008179 adenylate cyclase binding 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0008603 cAMP-dependent protein kinase regulator activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0015132 prostaglandin transmembrane transporter activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0015166 polyol transmembrane transporter activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0016208 AMP binding 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0016273 arginine N-methyltransferase activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0016274 protein-arginine N-methyltransferase activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0016423 tRNA (guanine) methyltransferase activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0016801 hydrolase activity, acting on ether bonds 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0016803 ether hydrolase activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0017166 vinculin binding 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0034452 dynactin binding 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0036009 protein-glutamine N-methyltransferase activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0043047 single-stranded telomeric DNA binding 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0045295 gamma-catenin binding 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0070008 serine-type exopeptidase activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0070679 inositol 1,4,5 trisphosphate binding 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:1990817 poly(A) RNA polymerase activity 1/799 12/18639 0.0833333333333333 1.94399249061327 0.408985688993921 0.651038443704608 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/799 54/18639 0.0555555555555556 1.29599499374218 0.409802388093521 0.651316021201928 GO:0051536 iron-sulfur cluster binding 4/799 76/18639 0.0526315789473684 1.22778473091364 0.411677020994635 0.653271516883505 GO:0046982 protein heterodimerization activity 17/799 369/18639 0.046070460704607 1.0747275557862 0.415334870152212 0.658046184897411 GO:0019239 deaminase activity 2/799 33/18639 0.0606060606060606 1.41381272044601 0.416428952924865 0.658750324907664 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 22/799 484/18639 0.0454545454545455 1.06035954033451 0.419597670053133 0.662729030270836 GO:0051540 metal cluster binding 4/799 77/18639 0.051948051948052 1.21183947466801 0.421390331254665 0.664525343533795 GO:0019199 transmembrane receptor protein kinase activity 4/799 78/18639 0.0512820512820513 1.19630307114663 0.43106454326076 0.67136860237884 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/799 34/18639 0.0588235294117647 1.37222999337407 0.431368167758458 0.67136860237884 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/799 34/18639 0.0588235294117647 1.37222999337407 0.431368167758458 0.67136860237884 GO:0004535 poly(A)-specific ribonuclease activity 1/799 13/18639 0.0769230769230769 1.79445460671994 0.434337083984733 0.67136860237884 GO:0005542 folic acid binding 1/799 13/18639 0.0769230769230769 1.79445460671994 0.434337083984733 0.67136860237884 GO:0008253 5'-nucleotidase activity 1/799 13/18639 0.0769230769230769 1.79445460671994 0.434337083984733 0.67136860237884 GO:0031994 insulin-like growth factor I binding 1/799 13/18639 0.0769230769230769 1.79445460671994 0.434337083984733 0.67136860237884 GO:0039706 co-receptor binding 1/799 13/18639 0.0769230769230769 1.79445460671994 0.434337083984733 0.67136860237884 GO:0043560 insulin receptor substrate binding 1/799 13/18639 0.0769230769230769 1.79445460671994 0.434337083984733 0.67136860237884 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/799 13/18639 0.0769230769230769 1.79445460671994 0.434337083984733 0.67136860237884 GO:0046975 histone H3K36 methyltransferase activity 1/799 13/18639 0.0769230769230769 1.79445460671994 0.434337083984733 0.67136860237884 GO:0071714 icosanoid transmembrane transporter activity 1/799 13/18639 0.0769230769230769 1.79445460671994 0.434337083984733 0.67136860237884 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/799 13/18639 0.0769230769230769 1.79445460671994 0.434337083984733 0.67136860237884 GO:0004601 peroxidase activity 3/799 57/18639 0.0526315789473684 1.22778473091364 0.444266367181483 0.685671379485577 GO:0000175 3'-5'-RNA exonuclease activity 2/799 35/18639 0.0571428571428571 1.33302342213481 0.446100727894174 0.686037467784725 GO:0005154 epidermal growth factor receptor binding 2/799 35/18639 0.0571428571428571 1.33302342213481 0.446100727894174 0.686037467784725 GO:0001216 DNA-binding transcription activator activity 22/799 491/18639 0.044806517311609 1.04524239821161 0.446533263055147 0.686037467784725 GO:0004705 JUN kinase activity 1/799 14/18639 0.0714285714285714 1.66627927766851 0.458602340609676 0.696073808320058 GO:0008559 ABC-type xenobiotic transporter activity 1/799 14/18639 0.0714285714285714 1.66627927766851 0.458602340609676 0.696073808320058 GO:0016530 metallochaperone activity 1/799 14/18639 0.0714285714285714 1.66627927766851 0.458602340609676 0.696073808320058 GO:0032036 myosin heavy chain binding 1/799 14/18639 0.0714285714285714 1.66627927766851 0.458602340609676 0.696073808320058 GO:0070742 C2H2 zinc finger domain binding 1/799 14/18639 0.0714285714285714 1.66627927766851 0.458602340609676 0.696073808320058 GO:0098847 sequence-specific single stranded DNA binding 1/799 14/18639 0.0714285714285714 1.66627927766851 0.458602340609676 0.696073808320058 GO:1901612 cardiolipin binding 1/799 14/18639 0.0714285714285714 1.66627927766851 0.458602340609676 0.696073808320058 GO:0016409 palmitoyltransferase activity 2/799 36/18639 0.0555555555555556 1.29599499374218 0.460616888937632 0.696073808320058 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/799 36/18639 0.0555555555555556 1.29599499374218 0.460616888937632 0.696073808320058 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/799 36/18639 0.0555555555555556 1.29599499374218 0.460616888937632 0.696073808320058 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/799 36/18639 0.0555555555555556 1.29599499374218 0.460616888937632 0.696073808320058 GO:0036002 pre-mRNA binding 3/799 59/18639 0.0508474576271186 1.18616490952674 0.466796326073332 0.704362313449938 GO:0030280 structural constituent of skin epidermis 2/799 37/18639 0.0540540540540541 1.26096810201942 0.474908119211449 0.713246026217802 GO:0042805 actinin binding 2/799 37/18639 0.0540540540540541 1.26096810201942 0.474908119211449 0.713246026217802 GO:0043394 proteoglycan binding 2/799 37/18639 0.0540540540540541 1.26096810201942 0.474908119211449 0.713246026217802 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/799 60/18639 0.05 1.16639549436796 0.477908513906996 0.713246026217802 GO:0000774 adenyl-nucleotide exchange factor activity 1/799 15/18639 0.0666666666666667 1.55519399249061 0.481827936843387 0.713246026217802 GO:0004129 cytochrome-c oxidase activity 1/799 15/18639 0.0666666666666667 1.55519399249061 0.481827936843387 0.713246026217802 GO:0004559 alpha-mannosidase activity 1/799 15/18639 0.0666666666666667 1.55519399249061 0.481827936843387 0.713246026217802 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/799 15/18639 0.0666666666666667 1.55519399249061 0.481827936843387 0.713246026217802 GO:0004953 icosanoid receptor activity 1/799 15/18639 0.0666666666666667 1.55519399249061 0.481827936843387 0.713246026217802 GO:0005041 low-density lipoprotein particle receptor activity 1/799 15/18639 0.0666666666666667 1.55519399249061 0.481827936843387 0.713246026217802 GO:0008252 nucleotidase activity 1/799 15/18639 0.0666666666666667 1.55519399249061 0.481827936843387 0.713246026217802 GO:0016846 carbon-sulfur lyase activity 1/799 15/18639 0.0666666666666667 1.55519399249061 0.481827936843387 0.713246026217802 GO:0031005 filamin binding 1/799 15/18639 0.0666666666666667 1.55519399249061 0.481827936843387 0.713246026217802 GO:0003774 cytoskeletal motor activity 7/799 153/18639 0.0457516339869281 1.0672899948465 0.484949489398957 0.71682038228942 GO:0004860 protein kinase inhibitor activity 4/799 84/18639 0.0476190476190476 1.11085285177901 0.488029675443393 0.719611831803872 GO:0042162 telomeric DNA binding 2/799 38/18639 0.0526315789473684 1.22778473091364 0.488967013918016 0.719611831803872 GO:0043531 ADP binding 2/799 38/18639 0.0526315789473684 1.22778473091364 0.488967013918016 0.719611831803872 GO:0005506 iron ion binding 7/799 154/18639 0.0454545454545455 1.06035954033451 0.491825989938912 0.722770367823271 GO:0022804 active transmembrane transporter activity 20/799 457/18639 0.0437636761487965 1.0209150935387 0.494811416708845 0.723959180261529 GO:0005096 GTPase activator activity 12/799 271/18639 0.044280442804428 1.03297017951406 0.496066915979813 0.723959180261529 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/799 39/18639 0.0512820512820513 1.19630307114663 0.502787214418014 0.723959180261529 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/799 39/18639 0.0512820512820513 1.19630307114663 0.502787214418014 0.723959180261529 GO:0000062 fatty-acyl-CoA binding 1/799 16/18639 0.0625 1.45799436795995 0.504058364166311 0.723959180261529 GO:0003688 DNA replication origin binding 1/799 16/18639 0.0625 1.45799436795995 0.504058364166311 0.723959180261529 GO:0004707 MAP kinase activity 1/799 16/18639 0.0625 1.45799436795995 0.504058364166311 0.723959180261529 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/799 16/18639 0.0625 1.45799436795995 0.504058364166311 0.723959180261529 GO:0008296 3'-5'-DNA exonuclease activity 1/799 16/18639 0.0625 1.45799436795995 0.504058364166311 0.723959180261529 GO:0015562 efflux transmembrane transporter activity 1/799 16/18639 0.0625 1.45799436795995 0.504058364166311 0.723959180261529 GO:0015923 mannosidase activity 1/799 16/18639 0.0625 1.45799436795995 0.504058364166311 0.723959180261529 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/799 16/18639 0.0625 1.45799436795995 0.504058364166311 0.723959180261529 GO:0017070 U6 snRNA binding 1/799 16/18639 0.0625 1.45799436795995 0.504058364166311 0.723959180261529 GO:0030275 LRR domain binding 1/799 16/18639 0.0625 1.45799436795995 0.504058364166311 0.723959180261529 GO:0055102 lipase inhibitor activity 1/799 16/18639 0.0625 1.45799436795995 0.504058364166311 0.723959180261529 GO:0097027 ubiquitin-protein transferase activator activity 1/799 16/18639 0.0625 1.45799436795995 0.504058364166311 0.723959180261529 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/799 86/18639 0.0465116279069767 1.08501906452833 0.506507193324993 0.726447374867812 GO:0016853 isomerase activity 8/799 180/18639 0.0444444444444444 1.03679599499374 0.509498071839869 0.729704865601169 GO:0015144 carbohydrate transmembrane transporter activity 2/799 40/18639 0.05 1.16639549436796 0.516363332344666 0.729713588136406 GO:0030331 nuclear estrogen receptor binding 2/799 40/18639 0.05 1.16639549436796 0.516363332344666 0.729713588136406 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/799 40/18639 0.05 1.16639549436796 0.516363332344666 0.729713588136406 GO:0050997 quaternary ammonium group binding 2/799 40/18639 0.05 1.16639549436796 0.516363332344666 0.729713588136406 GO:0071949 FAD binding 2/799 40/18639 0.05 1.16639549436796 0.516363332344666 0.729713588136406 GO:0140662 ATP-dependent protein folding chaperone 2/799 40/18639 0.05 1.16639549436796 0.516363332344666 0.729713588136406 GO:1902936 phosphatidylinositol bisphosphate binding 5/799 111/18639 0.045045045045045 1.05080675168285 0.51956321891419 0.729713588136406 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/799 17/18639 0.0588235294117647 1.37222999337407 0.525336212366446 0.729713588136406 GO:0005092 GDP-dissociation inhibitor activity 1/799 17/18639 0.0588235294117647 1.37222999337407 0.525336212366446 0.729713588136406 GO:0009881 photoreceptor activity 1/799 17/18639 0.0588235294117647 1.37222999337407 0.525336212366446 0.729713588136406 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/799 17/18639 0.0588235294117647 1.37222999337407 0.525336212366446 0.729713588136406 GO:0016018 cyclosporin A binding 1/799 17/18639 0.0588235294117647 1.37222999337407 0.525336212366446 0.729713588136406 GO:0019198 transmembrane receptor protein phosphatase activity 1/799 17/18639 0.0588235294117647 1.37222999337407 0.525336212366446 0.729713588136406 GO:0031489 myosin V binding 1/799 17/18639 0.0588235294117647 1.37222999337407 0.525336212366446 0.729713588136406 GO:0032977 membrane insertase activity 1/799 17/18639 0.0588235294117647 1.37222999337407 0.525336212366446 0.729713588136406 GO:0038191 neuropilin binding 1/799 17/18639 0.0588235294117647 1.37222999337407 0.525336212366446 0.729713588136406 GO:0045236 CXCR chemokine receptor binding 1/799 17/18639 0.0588235294117647 1.37222999337407 0.525336212366446 0.729713588136406 GO:0046965 nuclear retinoid X receptor binding 1/799 17/18639 0.0588235294117647 1.37222999337407 0.525336212366446 0.729713588136406 GO:0070402 NADPH binding 1/799 17/18639 0.0588235294117647 1.37222999337407 0.525336212366446 0.729713588136406 GO:0070492 oligosaccharide binding 1/799 17/18639 0.0588235294117647 1.37222999337407 0.525336212366446 0.729713588136406 GO:1901567 fatty acid derivative binding 1/799 17/18639 0.0588235294117647 1.37222999337407 0.525336212366446 0.729713588136406 GO:1990226 histone methyltransferase binding 1/799 17/18639 0.0588235294117647 1.37222999337407 0.525336212366446 0.729713588136406 GO:0001530 lipopolysaccharide binding 2/799 41/18639 0.0487804878048781 1.13794682377362 0.529690878288286 0.730757211679349 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/799 41/18639 0.0487804878048781 1.13794682377362 0.529690878288286 0.730757211679349 GO:0042169 SH2 domain binding 2/799 41/18639 0.0487804878048781 1.13794682377362 0.529690878288286 0.730757211679349 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/799 41/18639 0.0487804878048781 1.13794682377362 0.529690878288286 0.730757211679349 GO:0140828 metal cation:monoatomic cation antiporter activity 2/799 41/18639 0.0487804878048781 1.13794682377362 0.529690878288286 0.730757211679349 GO:0061135 endopeptidase regulator activity 8/799 184/18639 0.0434782608695652 1.01425695162431 0.534598124667948 0.736525133713722 GO:0019210 kinase inhibitor activity 4/799 90/18639 0.0444444444444444 1.03679599499374 0.542526725747588 0.738774475614805 GO:0016859 cis-trans isomerase activity 2/799 42/18639 0.0476190476190476 1.11085285177901 0.54276619479952 0.738774475614805 GO:0019894 kinesin binding 2/799 42/18639 0.0476190476190476 1.11085285177901 0.54276619479952 0.738774475614805 GO:0031492 nucleosomal DNA binding 2/799 42/18639 0.0476190476190476 1.11085285177901 0.54276619479952 0.738774475614805 GO:0042056 chemoattractant activity 2/799 42/18639 0.0476190476190476 1.11085285177901 0.54276619479952 0.738774475614805 GO:0004706 JUN kinase kinase kinase activity 1/799 18/18639 0.0555555555555556 1.29599499374218 0.545702250725334 0.738774475614805 GO:0008409 5'-3' exonuclease activity 1/799 18/18639 0.0555555555555556 1.29599499374218 0.545702250725334 0.738774475614805 GO:0030228 lipoprotein particle receptor activity 1/799 18/18639 0.0555555555555556 1.29599499374218 0.545702250725334 0.738774475614805 GO:0032393 MHC class I receptor activity 1/799 18/18639 0.0555555555555556 1.29599499374218 0.545702250725334 0.738774475614805 GO:0035615 clathrin adaptor activity 1/799 18/18639 0.0555555555555556 1.29599499374218 0.545702250725334 0.738774475614805 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/799 18/18639 0.0555555555555556 1.29599499374218 0.545702250725334 0.738774475614805 GO:0098641 cadherin binding involved in cell-cell adhesion 1/799 18/18639 0.0555555555555556 1.29599499374218 0.545702250725334 0.738774475614805 GO:0099602 neurotransmitter receptor regulator activity 1/799 18/18639 0.0555555555555556 1.29599499374218 0.545702250725334 0.738774475614805 GO:0140767 enzyme-substrate adaptor activity 6/799 139/18639 0.0431654676258993 1.0069601390227 0.551606669195654 0.745772216752524 GO:0042054 histone methyltransferase activity 3/799 67/18639 0.0447761194029851 1.04453327853847 0.552372722162987 0.74581350236121 GO:0005245 voltage-gated calcium channel activity 2/799 43/18639 0.0465116279069767 1.08501906452833 0.55558639347279 0.749155057156129 GO:0005520 insulin-like growth factor binding 1/799 19/18639 0.0526315789473684 1.22778473091364 0.565195505742275 0.753098873617171 GO:0008301 DNA binding, bending 1/799 19/18639 0.0526315789473684 1.22778473091364 0.565195505742275 0.753098873617171 GO:0015245 fatty acid transmembrane transporter activity 1/799 19/18639 0.0526315789473684 1.22778473091364 0.565195505742275 0.753098873617171 GO:0034987 immunoglobulin receptor binding 1/799 19/18639 0.0526315789473684 1.22778473091364 0.565195505742275 0.753098873617171 GO:0042800 histone H3K4 methyltransferase activity 1/799 19/18639 0.0526315789473684 1.22778473091364 0.565195505742275 0.753098873617171 GO:0043395 heparan sulfate proteoglycan binding 1/799 19/18639 0.0526315789473684 1.22778473091364 0.565195505742275 0.753098873617171 GO:0050145 nucleoside monophosphate kinase activity 1/799 19/18639 0.0526315789473684 1.22778473091364 0.565195505742275 0.753098873617171 GO:0097001 ceramide binding 1/799 19/18639 0.0526315789473684 1.22778473091364 0.565195505742275 0.753098873617171 GO:0120227 acyl-CoA binding 1/799 19/18639 0.0526315789473684 1.22778473091364 0.565195505742275 0.753098873617171 GO:0030547 signaling receptor inhibitor activity 2/799 44/18639 0.0454545454545455 1.06035954033451 0.568149295883931 0.7560411890109 GO:0016279 protein-lysine N-methyltransferase activity 3/799 69/18639 0.0434782608695652 1.01425695162431 0.572462760604983 0.760782751315141 GO:0016278 lysine N-methyltransferase activity 3/799 70/18639 0.0428571428571429 0.999767566601109 0.582295112384615 0.770868857085707 GO:0001972 retinoic acid binding 1/799 20/18639 0.05 1.16639549436796 0.583853335544204 0.770868857085707 GO:0015095 magnesium ion transmembrane transporter activity 1/799 20/18639 0.05 1.16639549436796 0.583853335544204 0.770868857085707 GO:0030742 GTP-dependent protein binding 1/799 20/18639 0.05 1.16639549436796 0.583853335544204 0.770868857085707 GO:0140939 histone H4 methyltransferase activity 1/799 20/18639 0.05 1.16639549436796 0.583853335544204 0.770868857085707 GO:0008276 protein methyltransferase activity 4/799 95/18639 0.0421052631578947 0.982227784730914 0.585569337622388 0.772129139595711 GO:0140299 molecular sensor activity 3/799 71/18639 0.0422535211267606 0.985686333268698 0.5919827695271 0.778228869300257 GO:0030276 clathrin binding 2/799 46/18639 0.0434782608695652 1.01425695162431 0.592497719033332 0.778228869300257 GO:0030291 protein serine/threonine kinase inhibitor activity 2/799 46/18639 0.0434782608695652 1.01425695162431 0.592497719033332 0.778228869300257 GO:0004540 RNA nuclease activity 5/799 121/18639 0.0413223140495868 0.963963218485917 0.596705583927804 0.780224376135678 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/799 21/18639 0.0476190476190476 1.11085285177901 0.601711501122387 0.780224376135678 GO:0008373 sialyltransferase activity 1/799 21/18639 0.0476190476190476 1.11085285177901 0.601711501122387 0.780224376135678 GO:0009975 cyclase activity 1/799 21/18639 0.0476190476190476 1.11085285177901 0.601711501122387 0.780224376135678 GO:0010314 phosphatidylinositol-5-phosphate binding 1/799 21/18639 0.0476190476190476 1.11085285177901 0.601711501122387 0.780224376135678 GO:0019200 carbohydrate kinase activity 1/799 21/18639 0.0476190476190476 1.11085285177901 0.601711501122387 0.780224376135678 GO:0036122 BMP binding 1/799 21/18639 0.0476190476190476 1.11085285177901 0.601711501122387 0.780224376135678 GO:0061891 calcium ion sensor activity 1/799 21/18639 0.0476190476190476 1.11085285177901 0.601711501122387 0.780224376135678 GO:0140312 cargo adaptor activity 1/799 21/18639 0.0476190476190476 1.11085285177901 0.601711501122387 0.780224376135678 GO:1904047 S-adenosyl-L-methionine binding 1/799 21/18639 0.0476190476190476 1.11085285177901 0.601711501122387 0.780224376135678 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 5/799 122/18639 0.040983606557377 0.956061880629475 0.604032277963852 0.782233371462766 GO:0032266 phosphatidylinositol-3-phosphate binding 2/799 48/18639 0.0416666666666667 0.971996245306633 0.61580621483369 0.795807399455055 GO:0042393 histone binding 10/799 247/18639 0.0404858299595142 0.944449793010494 0.618463539414034 0.795807399455055 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/799 22/18639 0.0454545454545455 1.06035954033451 0.618804234531089 0.795807399455055 GO:0140784 metal ion sensor activity 1/799 22/18639 0.0454545454545455 1.06035954033451 0.618804234531089 0.795807399455055 GO:0031491 nucleosome binding 3/799 74/18639 0.0405405405405405 0.945726076514562 0.620160394014993 0.795807399455055 GO:0001664 G protein-coupled receptor binding 12/799 297/18639 0.0404040404040404 0.942541813630675 0.624522757687546 0.795807399455055 GO:0005004 GPI-linked ephrin receptor activity 2/799 49/18639 0.0408163265306122 0.952159587239151 0.627071116533125 0.795807399455055 GO:0005008 hepatocyte growth factor receptor activity 2/799 49/18639 0.0408163265306122 0.952159587239151 0.627071116533125 0.795807399455055 GO:0005009 insulin receptor activity 2/799 49/18639 0.0408163265306122 0.952159587239151 0.627071116533125 0.795807399455055 GO:0005011 macrophage colony-stimulating factor receptor activity 2/799 49/18639 0.0408163265306122 0.952159587239151 0.627071116533125 0.795807399455055 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/799 49/18639 0.0408163265306122 0.952159587239151 0.627071116533125 0.795807399455055 GO:0005020 stem cell factor receptor activity 2/799 49/18639 0.0408163265306122 0.952159587239151 0.627071116533125 0.795807399455055 GO:0008288 boss receptor activity 2/799 49/18639 0.0408163265306122 0.952159587239151 0.627071116533125 0.795807399455055 GO:0036332 placental growth factor receptor activity 2/799 49/18639 0.0408163265306122 0.952159587239151 0.627071116533125 0.795807399455055 GO:0038062 protein tyrosine kinase collagen receptor activity 2/799 49/18639 0.0408163265306122 0.952159587239151 0.627071116533125 0.795807399455055 GO:0060175 brain-derived neurotrophic factor receptor activity 2/799 49/18639 0.0408163265306122 0.952159587239151 0.627071116533125 0.795807399455055 GO:0003887 DNA-directed DNA polymerase activity 1/799 23/18639 0.0434782608695652 1.01425695162431 0.63516430417763 0.796957587023238 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/799 23/18639 0.0434782608695652 1.01425695162431 0.63516430417763 0.796957587023238 GO:0005212 structural constituent of eye lens 1/799 23/18639 0.0434782608695652 1.01425695162431 0.63516430417763 0.796957587023238 GO:0016849 phosphorus-oxygen lyase activity 1/799 23/18639 0.0434782608695652 1.01425695162431 0.63516430417763 0.796957587023238 GO:0017134 fibroblast growth factor binding 1/799 23/18639 0.0434782608695652 1.01425695162431 0.63516430417763 0.796957587023238 GO:0042171 lysophosphatidic acid acyltransferase activity 1/799 23/18639 0.0434782608695652 1.01425695162431 0.63516430417763 0.796957587023238 GO:0071617 lysophospholipid acyltransferase activity 1/799 23/18639 0.0434782608695652 1.01425695162431 0.63516430417763 0.796957587023238 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/799 23/18639 0.0434782608695652 1.01425695162431 0.63516430417763 0.796957587023238 GO:0005006 epidermal growth factor receptor activity 2/799 50/18639 0.04 0.933116395494368 0.638077687495295 0.796957587023238 GO:0005007 fibroblast growth factor receptor activity 2/799 50/18639 0.04 0.933116395494368 0.638077687495295 0.796957587023238 GO:0005017 platelet-derived growth factor receptor activity 2/799 50/18639 0.04 0.933116395494368 0.638077687495295 0.796957587023238 GO:0005019 platelet-derived growth factor beta-receptor activity 2/799 50/18639 0.04 0.933116395494368 0.638077687495295 0.796957587023238 GO:0098631 cell adhesion mediator activity 3/799 76/18639 0.0394736842105263 0.920838548185232 0.638194833000857 0.796957587023238 GO:0005010 insulin-like growth factor receptor activity 2/799 51/18639 0.0392156862745098 0.914819995582714 0.648827346914182 0.798952300738872 GO:0005021 vascular endothelial growth factor receptor activity 2/799 51/18639 0.0392156862745098 0.914819995582714 0.648827346914182 0.798952300738872 GO:0005030 neurotrophin receptor activity 2/799 51/18639 0.0392156862745098 0.914819995582714 0.648827346914182 0.798952300738872 GO:0030544 Hsp70 protein binding 2/799 51/18639 0.0392156862745098 0.914819995582714 0.648827346914182 0.798952300738872 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/799 24/18639 0.0416666666666667 0.971996245306633 0.65082307732772 0.798952300738872 GO:0005540 hyaluronic acid binding 1/799 24/18639 0.0416666666666667 0.971996245306633 0.65082307732772 0.798952300738872 GO:0015149 hexose transmembrane transporter activity 1/799 24/18639 0.0416666666666667 0.971996245306633 0.65082307732772 0.798952300738872 GO:0015295 solute:proton symporter activity 1/799 24/18639 0.0416666666666667 0.971996245306633 0.65082307732772 0.798952300738872 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/799 24/18639 0.0416666666666667 0.971996245306633 0.65082307732772 0.798952300738872 GO:0035035 histone acetyltransferase binding 1/799 24/18639 0.0416666666666667 0.971996245306633 0.65082307732772 0.798952300738872 GO:0048027 mRNA 5'-UTR binding 1/799 24/18639 0.0416666666666667 0.971996245306633 0.65082307732772 0.798952300738872 GO:0055056 D-glucose transmembrane transporter activity 1/799 24/18639 0.0416666666666667 0.971996245306633 0.65082307732772 0.798952300738872 GO:0070840 dynein complex binding 1/799 24/18639 0.0416666666666667 0.971996245306633 0.65082307732772 0.798952300738872 GO:0140612 DNA damage sensor activity 1/799 24/18639 0.0416666666666667 0.971996245306633 0.65082307732772 0.798952300738872 GO:0030246 carbohydrate binding 11/799 280/18639 0.0392857142857143 0.916453602717683 0.659262140392297 0.808333507083179 GO:0016835 carbon-oxygen lyase activity 3/799 79/18639 0.0379746835443038 0.885869995722501 0.664104920307552 0.810187620109761 GO:0033293 monocarboxylic acid binding 3/799 79/18639 0.0379746835443038 0.885869995722501 0.664104920307552 0.810187620109761 GO:0000030 mannosyltransferase activity 1/799 25/18639 0.04 0.933116395494368 0.665810579944704 0.810187620109761 GO:0008483 transaminase activity 1/799 25/18639 0.04 0.933116395494368 0.665810579944704 0.810187620109761 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/799 25/18639 0.04 0.933116395494368 0.665810579944704 0.810187620109761 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/799 25/18639 0.04 0.933116395494368 0.665810579944704 0.810187620109761 GO:0005003 ephrin receptor activity 2/799 53/18639 0.0377358490566038 0.880298486315441 0.669563338907278 0.810187620109761 GO:0005005 transmembrane-ephrin receptor activity 2/799 53/18639 0.0377358490566038 0.880298486315441 0.669563338907278 0.810187620109761 GO:0008146 sulfotransferase activity 2/799 53/18639 0.0377358490566038 0.880298486315441 0.669563338907278 0.810187620109761 GO:0017046 peptide hormone binding 2/799 53/18639 0.0377358490566038 0.880298486315441 0.669563338907278 0.810187620109761 GO:0038064 collagen receptor activity 2/799 53/18639 0.0377358490566038 0.880298486315441 0.669563338907278 0.810187620109761 GO:0000149 SNARE binding 4/799 106/18639 0.0377358490566038 0.880298486315441 0.671410346428213 0.81145422083219 GO:0000049 tRNA binding 3/799 80/18639 0.0375 0.87479662077597 0.672435902230711 0.811726196264215 GO:0004529 DNA exonuclease activity 1/799 26/18639 0.0384615384615385 0.897227303359969 0.680155553976303 0.813299211948079 GO:0008157 protein phosphatase 1 binding 1/799 26/18639 0.0384615384615385 0.897227303359969 0.680155553976303 0.813299211948079 GO:0008198 ferrous iron binding 1/799 26/18639 0.0384615384615385 0.897227303359969 0.680155553976303 0.813299211948079 GO:0030507 spectrin binding 1/799 26/18639 0.0384615384615385 0.897227303359969 0.680155553976303 0.813299211948079 GO:0034237 protein kinase A regulatory subunit binding 1/799 26/18639 0.0384615384615385 0.897227303359969 0.680155553976303 0.813299211948079 GO:0050750 low-density lipoprotein particle receptor binding 1/799 26/18639 0.0384615384615385 0.897227303359969 0.680155553976303 0.813299211948079 GO:0052742 phosphatidylinositol kinase activity 1/799 26/18639 0.0384615384615385 0.897227303359969 0.680155553976303 0.813299211948079 GO:0070006 metalloaminopeptidase activity 1/799 26/18639 0.0384615384615385 0.897227303359969 0.680155553976303 0.813299211948079 GO:0008374 O-acyltransferase activity 2/799 55/18639 0.0363636363636364 0.848287632267607 0.689296926209738 0.820046514415341 GO:0098632 cell-cell adhesion mediator activity 2/799 55/18639 0.0363636363636364 0.848287632267607 0.689296926209738 0.820046514415341 GO:0015297 antiporter activity 5/799 135/18639 0.037037037037037 0.863996662494785 0.691970704955801 0.820046514415341 GO:0140098 catalytic activity, acting on RNA 15/799 387/18639 0.0387596899224806 0.904182553773612 0.692382162244003 0.820046514415341 GO:0004364 glutathione transferase activity 1/799 27/18639 0.037037037037037 0.863996662494785 0.693885512197596 0.820046514415341 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/799 27/18639 0.037037037037037 0.863996662494785 0.693885512197596 0.820046514415341 GO:0005044 scavenger receptor activity 1/799 27/18639 0.037037037037037 0.863996662494785 0.693885512197596 0.820046514415341 GO:0005104 fibroblast growth factor receptor binding 1/799 27/18639 0.037037037037037 0.863996662494785 0.693885512197596 0.820046514415341 GO:0015252 proton channel activity 1/799 27/18639 0.037037037037037 0.863996662494785 0.693885512197596 0.820046514415341 GO:0035255 ionotropic glutamate receptor binding 1/799 27/18639 0.037037037037037 0.863996662494785 0.693885512197596 0.820046514415341 GO:0030165 PDZ domain binding 3/799 83/18639 0.036144578313253 0.843177465808164 0.696512791996341 0.822193214300686 GO:0016779 nucleotidyltransferase activity 5/799 136/18639 0.0367647058823529 0.857643745858794 0.698148215526155 0.822970596299507 GO:0170055 lipid transmembrane transporter activity 2/799 56/18639 0.0357142857142857 0.833139638834257 0.698794559579758 0.822970596299507 GO:0004527 exonuclease activity 3/799 84/18639 0.0357142857142857 0.833139638834257 0.704234388905709 0.82785815910435 GO:0016866 intramolecular transferase activity 1/799 28/18639 0.0357142857142857 0.833139638834257 0.707026790714366 0.82785815910435 GO:0045499 chemorepellent activity 1/799 28/18639 0.0357142857142857 0.833139638834257 0.707026790714366 0.82785815910435 GO:0051393 alpha-actinin binding 1/799 28/18639 0.0357142857142857 0.833139638834257 0.707026790714366 0.82785815910435 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/799 28/18639 0.0357142857142857 0.833139638834257 0.707026790714366 0.82785815910435 GO:0008408 3'-5' exonuclease activity 2/799 58/18639 0.0344827586206897 0.804410685771007 0.717066909556307 0.838645728131598 GO:0004181 metallocarboxypeptidase activity 1/799 29/18639 0.0344827586206897 0.804410685771007 0.719604599226494 0.840644082506527 GO:0005201 extracellular matrix structural constituent 6/799 168/18639 0.0357142857142857 0.833139638834257 0.731299938740452 0.851763573036645 GO:0001965 G-protein alpha-subunit binding 1/799 30/18639 0.0333333333333333 0.777596996245307 0.731643069146861 0.851763573036645 GO:0016769 transferase activity, transferring nitrogenous groups 1/799 30/18639 0.0333333333333333 0.777596996245307 0.731643069146861 0.851763573036645 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/799 60/18639 0.0333333333333333 0.777596996245307 0.734397982490965 0.853990314502108 GO:0016836 hydro-lyase activity 2/799 61/18639 0.0327868852459016 0.76484950450358 0.742719562496749 0.857303314974367 GO:0005164 tumor necrosis factor receptor binding 1/799 31/18639 0.032258064516129 0.752513222172877 0.743165299667129 0.857303314974367 GO:0005452 solute:inorganic anion antiporter activity 1/799 31/18639 0.032258064516129 0.752513222172877 0.743165299667129 0.857303314974367 GO:0016411 acylglycerol O-acyltransferase activity 1/799 31/18639 0.032258064516129 0.752513222172877 0.743165299667129 0.857303314974367 GO:0017147 Wnt-protein binding 1/799 31/18639 0.032258064516129 0.752513222172877 0.743165299667129 0.857303314974367 GO:0070273 phosphatidylinositol-4-phosphate binding 1/799 31/18639 0.032258064516129 0.752513222172877 0.743165299667129 0.857303314974367 GO:0070325 lipoprotein particle receptor binding 1/799 31/18639 0.032258064516129 0.752513222172877 0.743165299667129 0.857303314974367 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/799 91/18639 0.032967032967033 0.769051974308545 0.754110589747294 0.868050067518633 GO:0042910 xenobiotic transmembrane transporter activity 1/799 32/18639 0.03125 0.728997183979975 0.754193401857905 0.868050067518633 GO:0015293 symporter activity 5/799 146/18639 0.0342465753424658 0.798901023539699 0.755191794970469 0.868213696258566 GO:0005507 copper ion binding 2/799 63/18639 0.0317460317460317 0.740568567852673 0.758693866033225 0.871252072658765 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/799 33/18639 0.0303030303030303 0.706906360223006 0.764748540887063 0.876220362101109 GO:0030296 protein tyrosine kinase activator activity 1/799 33/18639 0.0303030303030303 0.706906360223006 0.764748540887063 0.876220362101109 GO:0019843 rRNA binding 2/799 65/18639 0.0307692307692308 0.717781842687975 0.773802780060397 0.881816936146492 GO:0008175 tRNA methyltransferase activity 1/799 34/18639 0.0294117647058824 0.686114996687035 0.774850976436414 0.881816936146492 GO:0015020 glucuronosyltransferase activity 1/799 34/18639 0.0294117647058824 0.686114996687035 0.774850976436414 0.881816936146492 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/799 34/18639 0.0294117647058824 0.686114996687035 0.774850976436414 0.881816936146492 GO:0051427 hormone receptor binding 1/799 34/18639 0.0294117647058824 0.686114996687035 0.774850976436414 0.881816936146492 GO:0090482 vitamin transmembrane transporter activity 1/799 34/18639 0.0294117647058824 0.686114996687035 0.774850976436414 0.881816936146492 GO:0008235 metalloexopeptidase activity 2/799 66/18639 0.0303030303030303 0.706906360223006 0.781042862916786 0.88786711098388 GO:0005343 organic acid:sodium symporter activity 1/799 35/18639 0.0285714285714286 0.666511711067406 0.784520101393539 0.88875682764694 GO:0034061 DNA polymerase activity 1/799 35/18639 0.0285714285714286 0.666511711067406 0.784520101393539 0.88875682764694 GO:0061631 ubiquitin conjugating enzyme activity 1/799 35/18639 0.0285714285714286 0.666511711067406 0.784520101393539 0.88875682764694 GO:0046906 tetrapyrrole binding 5/799 152/18639 0.0328947368421053 0.767365456821026 0.785331476895127 0.88875682764694 GO:0016500 protein-hormone receptor activity 2/799 67/18639 0.0298507462686567 0.696355519025648 0.788078867247672 0.889879700878774 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/799 67/18639 0.0298507462686567 0.696355519025648 0.788078867247672 0.889879700878774 GO:0004190 aspartic-type endopeptidase activity 1/799 36/18639 0.0277777777777778 0.647997496871089 0.793774478892279 0.893326661039701 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/799 36/18639 0.0277777777777778 0.647997496871089 0.793774478892279 0.893326661039701 GO:0045505 dynein intermediate chain binding 1/799 36/18639 0.0277777777777778 0.647997496871089 0.793774478892279 0.893326661039701 GO:0140223 general transcription initiation factor activity 2/799 68/18639 0.0294117647058824 0.686114996687035 0.794914959261195 0.893618368836865 GO:0008170 N-methyltransferase activity 3/799 98/18639 0.0306122448979592 0.714119690429363 0.79698883314956 0.894957560148011 GO:0070001 aspartic-type peptidase activity 1/799 37/18639 0.027027027027027 0.630484051009708 0.802631877772302 0.900297261129551 GO:0005109 frizzled binding 1/799 38/18639 0.0263157894736842 0.613892365456821 0.811109306525121 0.906796953491149 GO:0005501 retinoid binding 1/799 38/18639 0.0263157894736842 0.613892365456821 0.811109306525121 0.906796953491149 GO:0019840 isoprenoid binding 1/799 38/18639 0.0263157894736842 0.613892365456821 0.811109306525121 0.906796953491149 GO:0016798 hydrolase activity, acting on glycosyl bonds 4/799 130/18639 0.0307692307692308 0.717781842687975 0.813526121976244 0.907497786230926 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4/799 130/18639 0.0307692307692308 0.717781842687975 0.813526121976244 0.907497786230926 GO:0008238 exopeptidase activity 3/799 102/18639 0.0294117647058824 0.686114996687035 0.818561108218424 0.91184650760941 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/799 39/18639 0.0256410256410256 0.598151535573313 0.819223045791097 0.91184650760941 GO:0042379 chemokine receptor binding 2/799 72/18639 0.0277777777777778 0.647997496871089 0.820343978417739 0.912092976003934 GO:0005253 monoatomic anion channel activity 3/799 103/18639 0.029126213592233 0.679453686039588 0.823639785665323 0.914754373126657 GO:0004177 aminopeptidase activity 1/799 40/18639 0.025 0.58319774718398 0.826988679469211 0.917468841336739 GO:0004175 endopeptidase activity 14/799 405/18639 0.0345679012345679 0.806396884995133 0.830512781254172 0.920371541193148 GO:0035064 methylated histone binding 2/799 74/18639 0.027027027027027 0.630484051009708 0.831967859560604 0.920677932798386 GO:0001727 lipid kinase activity 1/799 41/18639 0.024390243902439 0.56897341188681 0.834421124498734 0.920677932798386 GO:0008227 G protein-coupled amine receptor activity 1/799 41/18639 0.024390243902439 0.56897341188681 0.834421124498734 0.920677932798386 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/799 41/18639 0.024390243902439 0.56897341188681 0.834421124498734 0.920677932798386 GO:0005126 cytokine receptor binding 9/799 275/18639 0.0327272727272727 0.763458869040846 0.838370652386821 0.924030262521996 GO:0008307 structural constituent of muscle 1/799 42/18639 0.0238095238095238 0.555426425889505 0.841534659369446 0.926510471879065 GO:0140034 methylation-dependent protein binding 2/799 76/18639 0.0263157894736842 0.613892365456821 0.842908894137954 0.927016939973845 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 5/799 167/18639 0.029940119760479 0.698440415789198 0.848050016678826 0.929967300253415 GO:0016874 ligase activity 5/799 167/18639 0.029940119760479 0.698440415789198 0.848050016678826 0.929967300253415 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/799 43/18639 0.0232558139534884 0.542509532264167 0.848342951414605 0.929967300253415 GO:0140101 catalytic activity, acting on a tRNA 4/799 139/18639 0.0287769784172662 0.671306759348466 0.851904890934267 0.932863455083528 GO:0019205 nucleobase-containing compound kinase activity 1/799 44/18639 0.0227272727272727 0.530179770167254 0.854859082938574 0.934390341485861 GO:0030414 peptidase inhibitor activity 5/799 169/18639 0.029585798816568 0.690174848738438 0.855142245462406 0.934390341485861 GO:0015370 solute:sodium symporter activity 2/799 79/18639 0.0253164556962025 0.590579997148334 0.858111224565804 0.936625168686464 GO:0046915 transition metal ion transmembrane transporter activity 1/799 45/18639 0.0222222222222222 0.518397997496871 0.861095576228818 0.937863495484448 GO:0051539 4 iron, 4 sulfur cluster binding 1/799 45/18639 0.0222222222222222 0.518397997496871 0.861095576228818 0.937863495484448 GO:0016829 lyase activity 6/799 200/18639 0.03 0.699837296620776 0.862893705758548 0.938049084800342 GO:0020037 heme binding 4/799 142/18639 0.028169014084507 0.657124222179132 0.863116169742327 0.938049084800342 GO:0004180 carboxypeptidase activity 1/799 46/18639 0.0217391304347826 0.507128475812156 0.867064417499829 0.940324405716392 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/799 46/18639 0.0217391304347826 0.507128475812156 0.867064417499829 0.940324405716392 GO:0015291 secondary active transmembrane transporter activity 9/799 287/18639 0.0313588850174216 0.73153724385447 0.871296382956071 0.943492493530869 GO:0099095 ligand-gated monoatomic anion channel activity 1/799 47/18639 0.0212765957446809 0.496338508241685 0.872777079814551 0.943492493530869 GO:0140359 ABC-type transporter activity 1/799 47/18639 0.0212765957446809 0.496338508241685 0.872777079814551 0.943492493530869 GO:0008168 methyltransferase activity 6/799 204/18639 0.0294117647058824 0.686114996687035 0.874806134836933 0.944678829312726 GO:0005254 chloride channel activity 2/799 83/18639 0.0240963855421687 0.562118310538776 0.876289394568789 0.945273878822076 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/799 48/18639 0.0208333333333333 0.485998122653317 0.87824454502691 0.946376162228785 GO:0015294 solute:monoatomic cation symporter activity 3/799 116/18639 0.0258620689655172 0.603308014328255 0.879307939805315 0.946516189981517 GO:0004518 nuclease activity 6/799 209/18639 0.0287081339712919 0.669700762316532 0.888466678193089 0.951346972973947 GO:0015605 organophosphate ester transmembrane transporter activity 1/799 50/18639 0.02 0.466558197747184 0.888485480650297 0.951346972973947 GO:0032813 tumor necrosis factor receptor superfamily binding 1/799 50/18639 0.02 0.466558197747184 0.888485480650297 0.951346972973947 GO:0048020 CCR chemokine receptor binding 1/799 50/18639 0.02 0.466558197747184 0.888485480650297 0.951346972973947 GO:0050660 flavin adenine dinucleotide binding 2/799 86/18639 0.0232558139534884 0.542509532264167 0.888486768645294 0.951346972973947 GO:0016597 amino acid binding 1/799 51/18639 0.0196078431372549 0.457409997791357 0.893278643325019 0.955468928619799 GO:0005539 glycosaminoglycan binding 7/799 242/18639 0.0289256198347107 0.674774252940142 0.898354246696851 0.959885359484307 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/799 53/18639 0.0188679245283019 0.440149243157721 0.902256467489526 0.961990697719134 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/799 53/18639 0.0188679245283019 0.440149243157721 0.902256467489526 0.961990697719134 GO:0016741 transferase activity, transferring one-carbon groups 6/799 215/18639 0.027906976744186 0.651011438717001 0.903170753677136 0.961990697719134 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/799 54/18639 0.0185185185185185 0.431998331247393 0.906458398108049 0.963391449440664 GO:0050661 NADP binding 1/799 54/18639 0.0185185185185185 0.431998331247393 0.906458398108049 0.963391449440664 GO:0031406 carboxylic acid binding 5/799 187/18639 0.0267379679144385 0.623740906079123 0.907336128417982 0.963391449440664 GO:0052689 carboxylic ester hydrolase activity 2/799 92/18639 0.0217391304347826 0.507128475812156 0.909602679066721 0.964787778842736 GO:0043177 organic acid binding 5/799 189/18639 0.0264550264550265 0.617140473210561 0.911976679358887 0.966295039571486 GO:0030170 pyridoxal phosphate binding 1/799 56/18639 0.0178571428571429 0.416569819417129 0.914328731342673 0.966766771200699 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/799 56/18639 0.0178571428571429 0.416569819417129 0.914328731342673 0.966766771200699 GO:0070279 vitamin B6 binding 1/799 57/18639 0.0175438596491228 0.409261576971214 0.918012277791428 0.969157185604459 GO:0004866 endopeptidase inhibitor activity 4/799 161/18639 0.0248447204968944 0.579575400928179 0.918501040794758 0.969157185604459 GO:0008083 growth factor activity 4/799 162/18639 0.0246913580246914 0.575997774996523 0.920765413575642 0.970536517012163 GO:0005261 monoatomic cation channel activity 10/799 341/18639 0.0293255131964809 0.68410292924807 0.923227930180898 0.971243138942074 GO:0030594 neurotransmitter receptor activity 2/799 97/18639 0.0206185567010309 0.480987832729056 0.924276403044937 0.971243138942074 GO:0015081 sodium ion transmembrane transporter activity 4/799 164/18639 0.024390243902439 0.56897341188681 0.925125690006914 0.971243138942074 GO:0005179 hormone activity 3/799 132/18639 0.0227272727272727 0.530179770167254 0.926036235345016 0.971243138942074 GO:0042626 ATPase-coupled transmembrane transporter activity 2/799 98/18639 0.0204081632653061 0.476079793619575 0.926928227417758 0.971243138942074 GO:0015103 inorganic anion transmembrane transporter activity 4/799 165/18639 0.0242424242424242 0.565525088178405 0.927223895508143 0.971243138942074 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/799 60/18639 0.0166666666666667 0.388798498122653 0.928140632776005 0.971243138942074 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/799 61/18639 0.0163934426229508 0.38242475225179 0.931230983947326 0.972469843174654 GO:0019905 syntaxin binding 1/799 61/18639 0.0163934426229508 0.38242475225179 0.931230983947326 0.972469843174654 GO:0015179 L-amino acid transmembrane transporter activity 1/799 62/18639 0.0161290322580645 0.376256611086439 0.934188592076624 0.97417185040486 GO:0099094 ligand-gated monoatomic cation channel activity 3/799 136/18639 0.0220588235294118 0.514586247515276 0.934782258820442 0.97417185040486 GO:0004536 DNA nuclease activity 1/799 64/18639 0.015625 0.364498591989987 0.939728115213121 0.978320645612017 GO:0004497 monooxygenase activity 2/799 106/18639 0.0188679245283019 0.440149243157721 0.945195086322102 0.983002889774986 GO:0008173 RNA methyltransferase activity 1/799 67/18639 0.0149253731343284 0.348177759512824 0.947176487391983 0.984054260466671 GO:0098960 postsynaptic neurotransmitter receptor activity 1/799 69/18639 0.0144927536231884 0.338085650541438 0.951623955220884 0.987662938171931 GO:1901681 sulfur compound binding 7/799 275/18639 0.0254545454545455 0.593801342587325 0.953163716521326 0.987801100358226 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/799 70/18639 0.0142857142857143 0.333255855533703 0.953705401627912 0.987801100358226 GO:0008509 monoatomic anion transmembrane transporter activity 3/799 149/18639 0.0201342281879195 0.469689460819313 0.95703352991506 0.988679095913594 GO:0008237 metallopeptidase activity 4/799 184/18639 0.0217391304347826 0.507128475812156 0.958201216094148 0.988679095913594 GO:0019842 vitamin binding 3/799 150/18639 0.02 0.466558197747184 0.958411391575193 0.988679095913594 GO:0004521 RNA endonuclease activity 1/799 73/18639 0.0136986301369863 0.319560409415879 0.959428235087748 0.988679095913594 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/799 73/18639 0.0136986301369863 0.319560409415879 0.959428235087748 0.988679095913594 GO:0046943 carboxylic acid transmembrane transporter activity 4/799 188/18639 0.0212765957446809 0.496338508241685 0.962928044439579 0.991278210214957 GO:0005342 organic acid transmembrane transporter activity 4/799 189/18639 0.0211640211640212 0.493712378568449 0.964029695576459 0.991405792408245 GO:0015108 chloride transmembrane transporter activity 2/799 121/18639 0.0165289256198347 0.385585287394367 0.968377949557804 0.994868531764552 GO:0008528 G protein-coupled peptide receptor activity 2/799 122/18639 0.0163934426229508 0.38242475225179 0.969529568395216 0.995043504405616 GO:0015101 organic cation transmembrane transporter activity 1/799 81/18639 0.0123456790123457 0.287998887498262 0.971466142552088 0.996022920675245 GO:0005216 monoatomic ion channel activity 12/799 448/18639 0.0267857142857143 0.624854729125693 0.97254214256665 0.996118921780387 GO:0001653 peptide receptor activity 2/799 128/18639 0.015625 0.364498591989987 0.975635357990363 0.99749460288101 GO:0008514 organic anion transmembrane transporter activity 6/799 269/18639 0.0223048327137546 0.52032512759909 0.975852708143947 0.99749460288101 GO:0008201 heparin binding 3/799 172/18639 0.0174418604651163 0.406882149198126 0.980013637732863 0.999670156486176 GO:0005244 voltage-gated monoatomic ion channel activity 3/799 173/18639 0.0173410404624277 0.404530229260564 0.980681120210927 0.999670156486176 GO:0022832 voltage-gated channel activity 3/799 175/18639 0.0171428571428571 0.399907026640443 0.981952814322324 0.999670156486176 GO:0004867 serine-type endopeptidase inhibitor activity 1/799 95/18639 0.0105263157894737 0.245556946182728 0.984594090478449 0.999670156486176 GO:0022843 voltage-gated monoatomic cation channel activity 2/799 143/18639 0.013986013986014 0.32626447394908 0.986168110356683 0.999670156486176 GO:0046873 metal ion transmembrane transporter activity 11/799 450/18639 0.0244444444444444 0.570237797246558 0.986705328426528 0.999670156486176 GO:0015276 ligand-gated monoatomic ion channel activity 3/799 186/18639 0.0161290322580645 0.376256611086439 0.987635138738272 0.999670156486176 GO:0022834 ligand-gated channel activity 3/799 188/18639 0.0159574468085106 0.372253881181264 0.988463930276978 0.999670156486176 GO:0015171 amino acid transmembrane transporter activity 1/799 102/18639 0.00980392156862745 0.228704998895678 0.9886819062143 0.999670156486176 GO:0008236 serine-type peptidase activity 3/799 194/18639 0.0154639175257732 0.360740874546792 0.990641916709834 0.999670156486176 GO:0005125 cytokine activity 4/799 234/18639 0.0170940170940171 0.398767690382209 0.991284551362108 0.999670156486176 GO:0017171 serine hydrolase activity 3/799 198/18639 0.0151515151515152 0.353453180111503 0.991867534231547 0.999670156486176 GO:0004222 metalloendopeptidase activity 1/799 110/18639 0.00909090909090909 0.212071908066902 0.992044539274693 0.999670156486176 GO:0015079 potassium ion transmembrane transporter activity 2/799 160/18639 0.0125 0.29159887359199 0.992795138805935 0.999670156486176 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/799 122/18639 0.00819672131147541 0.191212376125895 0.995313197586698 0.999670156486176 GO:0003735 structural constituent of ribosome 2/799 175/18639 0.0114285714285714 0.266604684426962 0.995979596585381 0.999670156486176 GO:0004519 endonuclease activity 1/799 127/18639 0.0078740157480315 0.183684329821726 0.996240878002397 0.999670156486176 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/799 132/18639 0.00757575757575758 0.176726590055752 0.996985122009221 0.999670156486176 GO:0022836 gated channel activity 5/799 318/18639 0.0157232704402516 0.366791035964767 0.99809977463546 0.999670156486176 GO:0045182 translation regulator activity 5/799 356/18639 0.0140449438202247 0.327639183811225 0.999465386337792 0.999670156486176 GO:0004252 serine-type endopeptidase activity 1/799 176/18639 0.00568181818181818 0.132544942541814 0.999568540566436 0.999670156486176 GO:0030371 translation repressor activity 4/799 329/18639 0.0121580547112462 0.283622004709534 0.999670156486176 0.999670156486176