ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003712 transcription coregulator activity 52/809 495/18639 0.105050505050505 2.42031688953815 3.60411018160578e-09 3.52842386779206e-06 GO:0106310 protein serine kinase activity 39/809 361/18639 0.10803324099723 2.48903779845163 1.60659513410777e-07 7.86428318145756e-05 GO:0004674 protein serine/threonine kinase activity 43/809 433/18639 0.0993071593533487 2.28799276042901 3.98341396134838e-07 0.000129992075605335 GO:0035173 histone kinase activity 37/809 360/18639 0.102777777777778 2.3679542645241 1.13226216132145e-06 0.000277121163983425 GO:0140996 histone H3 kinase activity 36/809 357/18639 0.100840336134454 2.32331647121148 2.45804634738144e-06 0.000481285474817287 GO:0003725 double-stranded RNA binding 14/809 75/18639 0.186666666666667 4.30071693448702 3.59027523357516e-06 0.000585813242278348 GO:0141003 histone H2AX kinase activity 35/809 354/18639 0.0988700564971751 2.27792210513084 5.25728887886093e-06 0.000735269401772121 GO:0001222 transcription corepressor binding 11/809 49/18639 0.224489795918367 5.17214500138745 6.17895624756023e-06 0.000756149770795183 GO:0140297 DNA-binding transcription factor binding 43/809 488/18639 0.0881147540983607 2.03012472390525 8.98709795714452e-06 0.000977596544449387 GO:0140857 histone H3T45 kinase activity 26/809 246/18639 0.105691056910569 2.43507491935241 2.69074885236323e-05 0.00208459379000262 GO:0003714 transcription corepressor activity 23/809 204/18639 0.112745098039216 2.59759688795172 2.7955565192971e-05 0.00208459379000262 GO:0035403 histone H3T6 kinase activity 26/809 247/18639 0.105263157894737 2.42521631644005 2.88637367627326e-05 0.00208459379000262 GO:0001221 transcription coregulator binding 16/809 115/18639 0.139130434782609 3.20550330520772 3.6785346359334e-05 0.00208459379000262 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 25/809 243/18639 0.102880658436214 2.37032458911322 5.96047740677298e-05 0.00208459379000262 GO:0032182 ubiquitin-like protein binding 16/809 120/18639 0.133333333333333 3.07194066749073 6.23068775339863e-05 0.00208459379000262 GO:0004676 3-phosphoinositide-dependent protein kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0004711 ribosomal protein S6 kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0035175 histone H3S10 kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0035979 histone H2AXS139 kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0044022 histone H3S28 kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0044023 histone H4S1 kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0044024 histone H2AS1 kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0044025 histone H2BS14 kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0072354 histone H3T3 kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0072371 histone H2AS121 kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0072518 Rho-dependent protein serine/threonine kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0140823 histone H2BS36 kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0140855 histone H3S57 kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0140995 histone H2A kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0140997 histone H4 kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0140998 histone H2B kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:1990244 histone H2AT120 kinase activity 25/809 245/18639 0.102040816326531 2.35097500063066 6.81378971195953e-05 0.00208459379000262 GO:0004677 DNA-dependent protein kinase activity 25/809 246/18639 0.101626016260163 2.34141819168501 7.2801970490179e-05 0.00215979179120864 GO:0035402 histone H3T11 kinase activity 25/809 247/18639 0.101214574898785 2.33193876580774 7.77499697838103e-05 0.0022387417770103 GO:0019902 phosphatase binding 21/809 190/18639 0.110526315789474 2.54647713226205 8.21399869069594e-05 0.00225705376549584 GO:0004679 AMP-activated protein kinase activity 25/809 248/18639 0.100806451612903 2.32253578691335 8.29968698241575e-05 0.00225705376549584 GO:0061659 ubiquitin-like protein ligase activity 33/809 372/18639 0.0887096774193548 2.04383149248375 8.55273471249487e-05 0.00226271492807388 GO:0042277 peptide binding 25/809 249/18639 0.100401606425703 2.31320833395386 8.85582997924681e-05 0.00226271492807388 GO:0052742 phosphatidylinositol kinase activity 7/809 26/18639 0.269230769230769 6.20295711704859 9.01387969304202e-05 0.00226271492807388 GO:0030695 GTPase regulator activity 40/809 489/18639 0.081799591002045 1.88462617637468 9.63279933927847e-05 0.00235762763828841 GO:0060589 nucleoside-triphosphatase regulator activity 40/809 490/18639 0.0816326530612245 1.88078000050453 0.000100645398627166 0.0024032157379511 GO:0005096 GTPase activator activity 26/809 271/18639 0.0959409594095941 2.21043701166307 0.00013622010669734 0.00317522582039753 GO:0046875 ephrin receptor binding 7/809 28/18639 0.25 5.75988875154512 0.000150399282253868 0.00325905696958428 GO:0140375 immune receptor activity 18/809 156/18639 0.115384615384615 2.65841019302082 0.000150425998317384 0.00325905696958428 GO:0023023 MHC protein complex binding 8/809 37/18639 0.216216216216216 4.98152540674172 0.000153132401022346 0.00325905696958428 GO:0043394 proteoglycan binding 8/809 37/18639 0.216216216216216 4.98152540674172 0.000153132401022346 0.00325905696958428 GO:0019903 protein phosphatase binding 17/809 144/18639 0.118055555555556 2.71994746600742 0.000172230160733666 0.00358751760336722 GO:0140693 molecular condensate scaffold activity 9/809 48/18639 0.1875 4.31991656365884 0.000191080670758691 0.0038972495140158 GO:0042043 neurexin family protein binding 5/809 14/18639 0.357142857142857 8.22841250220731 0.000219496116897565 0.00438544282536156 GO:0070566 adenylyltransferase activity 7/809 30/18639 0.233333333333333 5.37589616810878 0.000239729369307492 0.0046939010510407 GO:0019787 ubiquitin-like protein transferase activity 38/809 479/18639 0.0793319415448852 1.82777263097048 0.000264605112628819 0.00507938049536498 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 30/809 349/18639 0.0859598853868195 1.9804775076946 0.000304044234024177 0.00572421740595519 GO:0001727 lipid kinase activity 8/809 41/18639 0.195121951219512 4.49552292803521 0.000325068622269426 0.00600456945663714 GO:0005201 extracellular matrix structural constituent 18/809 168/18639 0.107142857142857 2.46852375066219 0.000379159066825534 0.00680977275065105 GO:0043130 ubiquitin binding 13/809 100/18639 0.13 2.99514215080346 0.000382571502845564 0.00680977275065105 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 15/809 128/18639 0.1171875 2.69994785228677 0.000441222234671337 0.00771351013827212 GO:0140463 chromatin-protein adaptor activity 9/809 54/18639 0.166666666666667 3.83992583436341 0.00048027783735394 0.0082489825047282 GO:0016755 aminoacyltransferase activity 38/809 496/18639 0.0766129032258065 1.76512719805415 0.000520866249734667 0.00879186307741792 GO:0050840 extracellular matrix binding 10/809 67/18639 0.149253731343284 3.43873955316126 0.000590489818698075 0.00962468406725493 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 4/809 10/18639 0.4 9.21582200247219 0.000599699415835088 0.00962468406725493 GO:0032395 MHC class II receptor activity 4/809 10/18639 0.4 9.21582200247219 0.000599699415835088 0.00962468406725493 GO:0051020 GTPase binding 27/809 315/18639 0.0857142857142857 1.97481900052975 0.000623155803325834 0.00977839476723622 GO:0004715 non-membrane spanning protein tyrosine kinase activity 8/809 45/18639 0.177777777777778 4.09592088998764 0.000629253187268521 0.00977839476723622 GO:0005178 integrin binding 17/809 161/18639 0.105590062111801 2.43274804413086 0.000644599276350403 0.00986035455542257 GO:0016779 nucleotidyltransferase activity 15/809 136/18639 0.110294117647059 2.54112739038755 0.000838161935940936 0.0126240082351719 GO:0044389 ubiquitin-like protein ligase binding 27/809 322/18639 0.0838509316770186 1.93188815269215 0.000869280541291237 0.0128943280291533 GO:0023026 MHC class II protein complex binding 6/809 27/18639 0.222222222222222 5.11990111248455 0.000887634869079133 0.0129129499874718 GO:0016922 nuclear receptor binding 15/809 137/18639 0.109489051094891 2.52257901527523 0.000904370254782871 0.0129129499874718 GO:0048407 platelet-derived growth factor binding 4/809 11/18639 0.363636363636364 8.37802000224744 0.000910105770312109 0.0129129499874718 GO:0045309 protein phosphorylated amino acid binding 9/809 59/18639 0.152542372881356 3.51450839077329 0.000935575856033045 0.0130846966150907 GO:0005543 phospholipid binding 37/809 497/18639 0.0744466800804829 1.71521838074181 0.00103583873777776 0.0142829031589356 GO:0043395 heparan sulfate proteoglycan binding 5/809 19/18639 0.263157894736842 6.06304079110012 0.00106389454616016 0.01446601056515 GO:0035259 nuclear glucocorticoid receptor binding 4/809 12/18639 0.333333333333333 7.67985166872682 0.0013184701747992 0.017443004069303 GO:1990817 poly(A) RNA polymerase activity 4/809 12/18639 0.333333333333333 7.67985166872682 0.0013184701747992 0.017443004069303 GO:0016757 glycosyltransferase activity 23/809 267/18639 0.0861423220973783 1.98468076832266 0.0014292618810292 0.0186566317537012 GO:0051721 protein phosphatase 2A binding 6/809 30/18639 0.2 4.60791100123609 0.00159370746832068 0.0205294685721835 GO:0061630 ubiquitin protein ligase activity 28/809 353/18639 0.0793201133144476 1.82750011380468 0.00163004836185109 0.0207249006006781 GO:0019208 phosphatase regulator activity 13/809 117/18639 0.111111111111111 2.55995055624227 0.0016983860726088 0.0210862800145188 GO:0019207 kinase regulator activity 24/809 287/18639 0.0836236933797909 1.92665268344366 0.00170154864264247 0.0210862800145188 GO:0003713 transcription coactivator activity 22/809 256/18639 0.0859375 1.97996175834363 0.00184908270178272 0.0226281495630661 GO:0120013 lipid transfer activity 9/809 65/18639 0.138461538461538 3.19009223162499 0.00188910016793201 0.0228324575852523 GO:0035198 miRNA binding 7/809 42/18639 0.166666666666667 3.83992583436341 0.00202129594616013 0.0241323016011069 GO:0050321 tau-protein kinase activity 5/809 22/18639 0.227272727272727 5.23626250140465 0.00216265467264349 0.0255089027050359 GO:0004842 ubiquitin-protein transferase activity 33/809 449/18639 0.0734966592427617 1.69333032339411 0.00231886477987782 0.0262061601633297 GO:0048156 tau protein binding 7/809 43/18639 0.162790697674419 3.75062523356426 0.0023254709068654 0.0262061601633297 GO:0140789 histone phosphatase activity 14/809 136/18639 0.102941176470588 2.37171889769505 0.00237910850642183 0.0262061601633297 GO:0042578 phosphoric ester hydrolase activity 28/809 363/18639 0.0771349862258953 1.77715575805249 0.00244371285298251 0.0262061601633297 GO:0005161 platelet-derived growth factor receptor binding 4/809 14/18639 0.285714285714286 6.58273000176585 0.00248739668051217 0.0262061601633297 GO:0061665 SUMO ligase activity 4/809 14/18639 0.285714285714286 6.58273000176585 0.00248739668051217 0.0262061601633297 GO:0033192 calmodulin-dependent protein phosphatase activity 10/809 81/18639 0.123456790123457 2.84438950693586 0.00259652455142286 0.0262061601633297 GO:0140791 histone H2AXS140 phosphatase activity 10/809 81/18639 0.123456790123457 2.84438950693586 0.00259652455142286 0.0262061601633297 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 10/809 81/18639 0.123456790123457 2.84438950693586 0.00259652455142286 0.0262061601633297 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 10/809 81/18639 0.123456790123457 2.84438950693586 0.00259652455142286 0.0262061601633297 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 10/809 81/18639 0.123456790123457 2.84438950693586 0.00259652455142286 0.0262061601633297 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 10/809 81/18639 0.123456790123457 2.84438950693586 0.00259652455142286 0.0262061601633297 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 10/809 81/18639 0.123456790123457 2.84438950693586 0.00259652455142286 0.0262061601633297 GO:1990439 MAP kinase serine/threonine phosphatase activity 10/809 81/18639 0.123456790123457 2.84438950693586 0.00259652455142286 0.0262061601633297 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 5/809 23/18639 0.217391304347826 5.00859891438706 0.00266586817726173 0.026362474197366 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 5/809 23/18639 0.217391304347826 5.00859891438706 0.00266586817726173 0.026362474197366 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 10/809 82/18639 0.121951219512195 2.80970183002201 0.00284488453603344 0.0275756629779875 GO:0033549 MAP kinase phosphatase activity 10/809 82/18639 0.121951219512195 2.80970183002201 0.00284488453603344 0.0275756629779875 GO:0042605 peptide antigen binding 7/809 45/18639 0.155555555555556 3.58393077873918 0.00303849721198808 0.029163615397415 GO:0004713 protein tyrosine kinase activity 14/809 140/18639 0.1 2.30395550061805 0.00310995676347006 0.0292933023817086 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 10/809 83/18639 0.120481927710843 2.77585000074463 0.00311185234698436 0.0292933023817086 GO:0031625 ubiquitin protein ligase binding 24/809 302/18639 0.0794701986754967 1.8309580137362 0.00330507436664389 0.030815883856613 GO:0017018 myosin phosphatase activity 10/809 84/18639 0.119047619047619 2.74280416740244 0.00339839580912791 0.0312113974338686 GO:0061980 regulatory RNA binding 8/809 58/18639 0.137931034482759 3.17786965602489 0.00341125589930944 0.0312113974338686 GO:0140566 histone reader activity 6/809 35/18639 0.171428571428571 3.94963800105951 0.00362420405617157 0.032852738620296 GO:0031490 chromatin DNA binding 13/809 128/18639 0.1015625 2.3399548053152 0.00376422861845771 0.0338089891511019 GO:0004879 nuclear receptor activity 8/809 59/18639 0.135593220338983 3.12400745846515 0.00379959786688221 0.0338164210152517 GO:0001784 phosphotyrosine residue binding 7/809 47/18639 0.148936170212766 3.43142308602688 0.00390759212255755 0.0344642584503049 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 4/809 16/18639 0.25 5.75988875154512 0.00422011986423898 0.0357394329916092 GO:0098531 ligand-modulated transcription factor activity 8/809 60/18639 0.133333333333333 3.07194066749073 0.00422122117839074 0.0357394329916092 GO:0017124 SH3 domain binding 12/809 115/18639 0.104347826086957 2.40412747890579 0.00423470298981273 0.0357394329916092 GO:0035401 histone H3Y41 kinase activity 12/809 115/18639 0.104347826086957 2.40412747890579 0.00423470298981273 0.0357394329916092 GO:0140801 histone H2AXY142 kinase activity 12/809 115/18639 0.104347826086957 2.40412747890579 0.00423470298981273 0.0357394329916092 GO:0016763 pentosyltransferase activity 7/809 49/18639 0.142857142857143 3.29136500088292 0.00495318631761344 0.041445892349945 GO:0000287 magnesium ion binding 19/809 230/18639 0.0826086956521739 1.90326758746708 0.00559222395935887 0.046396502171291 GO:0045296 cadherin binding 25/809 334/18639 0.0748502994011976 1.72451759028297 0.00592217450728397 0.0487210827111849 GO:0031267 small GTPase binding 22/809 283/18639 0.0777385159010601 1.79106081320131 0.00617148155210083 0.0503490036625559 GO:0003779 actin binding 31/809 443/18639 0.0699774266365688 1.61224877018419 0.00629625627750845 0.0509424371543865 GO:0003697 single-stranded DNA binding 12/809 121/18639 0.0991735537190083 2.28491454606748 0.00635714673398048 0.0509883382242699 GO:0035091 phosphatidylinositol binding 22/809 284/18639 0.0774647887323944 1.78475426104215 0.00642524304278358 0.0509883382242699 GO:0019789 SUMO transferase activity 5/809 28/18639 0.178571428571429 4.11420625110366 0.00651025768951352 0.0509883382242699 GO:0141052 histone H3 demethylase activity 5/809 28/18639 0.178571428571429 4.11420625110366 0.00651025768951352 0.0509883382242699 GO:0051219 phosphoprotein binding 10/809 93/18639 0.10752688172043 2.47737150604091 0.00702802870474296 0.0546066674757409 GO:0046332 SMAD binding 9/809 79/18639 0.113924050632911 2.62475943108385 0.00711562095816859 0.0548519127405279 GO:0045322 unmethylated CpG binding 3/809 10/18639 0.3 6.91186650185414 0.00777409144753793 0.0589987250165863 GO:0051880 G-quadruplex DNA binding 3/809 10/18639 0.3 6.91186650185414 0.00777409144753793 0.0589987250165863 GO:0016791 phosphatase activity 21/809 273/18639 0.0769230769230769 1.77227346201388 0.00824262211673974 0.0620732850176016 GO:0032452 histone demethylase activity 5/809 30/18639 0.166666666666667 3.83992583436341 0.00879040419400095 0.0656931733276865 GO:0048487 beta-tubulin binding 6/809 42/18639 0.142857142857143 3.29136500088292 0.00906580621295455 0.0672380627460796 GO:0042826 histone deacetylase binding 12/809 127/18639 0.094488188976378 2.17696582735563 0.00924345772150816 0.068040188792154 GO:0001540 amyloid-beta binding 9/809 83/18639 0.108433734939759 2.49826500067017 0.00975822795140365 0.0712933221225684 GO:0004725 protein tyrosine phosphatase activity 10/809 98/18639 0.102040816326531 2.35097500063066 0.0100534116501567 0.072810170787171 GO:0140457 protein demethylase activity 5/809 31/18639 0.161290322580645 3.71605725906137 0.0101145896088409 0.072810170787171 GO:0097493 structural molecule activity conferring elasticity 3/809 11/18639 0.272727272727273 6.28351500168558 0.0103480860764976 0.0739472720357018 GO:0008194 UDP-glycosyltransferase activity 13/809 145/18639 0.0896551724137931 2.06561527641618 0.0105465356494255 0.0748192637738233 GO:0016504 peptidase activator activity 7/809 57/18639 0.12280701754386 2.82941903584672 0.0113226173034059 0.0781977739762852 GO:0001223 transcription coactivator binding 6/809 44/18639 0.136363636363636 3.14175750084279 0.0113422716084091 0.0781977739762852 GO:0030020 extracellular matrix structural constituent conferring tensile strength 6/809 44/18639 0.136363636363636 3.14175750084279 0.0113422716084091 0.0781977739762852 GO:0043014 alpha-tubulin binding 6/809 44/18639 0.136363636363636 3.14175750084279 0.0113422716084091 0.0781977739762852 GO:0120015 sterol transfer activity 5/809 32/18639 0.15625 3.5999304697157 0.0115692600630067 0.0782301067693414 GO:0033218 amide binding 19/809 247/18639 0.0769230769230769 1.77227346201388 0.0115866858851425 0.0782301067693414 GO:0042393 histone binding 19/809 247/18639 0.0769230769230769 1.77227346201388 0.0115866858851425 0.0782301067693414 GO:0009931 calcium-dependent protein serine/threonine kinase activity 4/809 21/18639 0.19047619047619 4.3884866678439 0.0116843861621183 0.0783494113199577 GO:0005518 collagen binding 8/809 72/18639 0.111111111111111 2.55995055624227 0.0125606915384659 0.0836524967085584 GO:0070063 RNA polymerase binding 7/809 59/18639 0.11864406779661 2.733506526157 0.013567379821781 0.0897463840913754 GO:0004722 protein serine/threonine phosphatase activity 10/809 103/18639 0.0970873786407767 2.23685000060005 0.0139813895485897 0.0918642977722776 GO:0003727 single-stranded RNA binding 9/809 89/18639 0.101123595505618 2.32984264107443 0.0150262066452731 0.0967806335902787 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 9/809 89/18639 0.101123595505618 2.32984264107443 0.0150262066452731 0.0967806335902787 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 9/809 89/18639 0.101123595505618 2.32984264107443 0.0150262066452731 0.0967806335902787 GO:0140793 histone H2AXY142 phosphatase activity 9/809 90/18639 0.1 2.30395550061805 0.0160751618973599 0.10243980056871 GO:0015026 coreceptor activity 7/809 61/18639 0.114754098360656 2.64388336136497 0.0161141259321567 0.10243980056871 GO:0010485 histone H4 acetyltransferase activity 5/809 35/18639 0.142857142857143 3.29136500088292 0.0167696568332974 0.104843529000357 GO:0004535 poly(A)-specific ribonuclease activity 3/809 13/18639 0.230769230769231 5.31682038604165 0.0168135179295771 0.104843529000357 GO:0046975 histone H3K36 methyltransferase activity 3/809 13/18639 0.230769230769231 5.31682038604165 0.0168135179295771 0.104843529000357 GO:0019888 protein phosphatase regulator activity 10/809 107/18639 0.0934579439252336 2.15322943982995 0.0178718185098793 0.110737407096024 GO:0030552 cAMP binding 4/809 24/18639 0.166666666666667 3.83992583436341 0.0187235650047614 0.113949752177875 GO:0035035 histone acetyltransferase binding 4/809 24/18639 0.166666666666667 3.83992583436341 0.0187235650047614 0.113949752177875 GO:0140030 modification-dependent protein binding 14/809 173/18639 0.0809248554913295 1.86447265945969 0.0187394383050438 0.113949752177875 GO:0004843 cysteine-type deubiquitinase activity 10/809 108/18639 0.0925925925925926 2.1332921302019 0.0189579235893517 0.114566711073922 GO:0004721 phosphoprotein phosphatase activity 14/809 175/18639 0.08 1.84316440049444 0.0204847715229288 0.12260556681188 GO:0048020 CCR chemokine receptor binding 6/809 50/18639 0.12 2.76474660074166 0.02053862406246 0.12260556681188 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 3/809 14/18639 0.214285714285714 4.93704750132439 0.0207206419065948 0.122942475312463 GO:0030551 cyclic nucleotide binding 5/809 37/18639 0.135135135135135 3.11345337921358 0.0209818096546437 0.123742118384917 GO:0003707 nuclear steroid receptor activity 4/809 25/18639 0.16 3.68632880098888 0.0215436882202476 0.124066298633073 GO:0008139 nuclear localization sequence binding 4/809 25/18639 0.16 3.68632880098888 0.0215436882202476 0.124066298633073 GO:0019211 phosphatase activator activity 4/809 25/18639 0.16 3.68632880098888 0.0215436882202476 0.124066298633073 GO:0120020 cholesterol transfer activity 4/809 25/18639 0.16 3.68632880098888 0.0215436882202476 0.124066298633073 GO:0019783 ubiquitin-like protein peptidase activity 11/809 127/18639 0.0866141732283465 1.99555200840933 0.0223924710940347 0.128200170766433 GO:0005085 guanyl-nucleotide exchange factor activity 17/809 230/18639 0.0739130434782609 1.7029236308916 0.02313250902364 0.131257509745532 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 5/809 38/18639 0.131578947368421 3.03152039555006 0.0233242148216645 0.131257509745532 GO:0005319 lipid transporter activity 14/809 178/18639 0.0786516853932584 1.81209983194678 0.0233287095972651 0.131257509745532 GO:0005080 protein kinase C binding 6/809 52/18639 0.115384615384615 2.65841019302082 0.0244795309461373 0.136945490264391 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 3/809 15/18639 0.2 4.60791100123609 0.0250816915265085 0.137949303395797 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 3/809 15/18639 0.2 4.60791100123609 0.0250816915265085 0.137949303395797 GO:0061578 K63-linked deubiquitinase activity 3/809 15/18639 0.2 4.60791100123609 0.0250816915265085 0.137949303395797 GO:0019209 kinase activator activity 12/809 148/18639 0.0810810810810811 1.86807202752815 0.0277890793378057 0.15198608196487 GO:0101005 deubiquitinase activity 10/809 115/18639 0.0869565217391304 2.00343956575482 0.0279553045072047 0.152045795069741 GO:0004532 RNA exonuclease activity 5/809 40/18639 0.125 2.87994437577256 0.0284994811894299 0.153302154310175 GO:0032451 demethylase activity 5/809 40/18639 0.125 2.87994437577256 0.0284994811894299 0.153302154310175 GO:0003925 G protein activity 6/809 54/18639 0.111111111111111 2.55995055624227 0.0288956432044187 0.154583796159158 GO:0019887 protein kinase regulator activity 18/809 255/18639 0.0705882352941176 1.62632152984803 0.029714240829659 0.156513831357449 GO:0015631 tubulin binding 25/809 385/18639 0.0649350649350649 1.49607500040133 0.0298722578336634 0.156513831357449 GO:0034450 ubiquitin-ubiquitin ligase activity 3/809 16/18639 0.1875 4.31991656365884 0.0298959003716476 0.156513831357449 GO:0140328 floppase activity 3/809 16/18639 0.1875 4.31991656365884 0.0298959003716476 0.156513831357449 GO:0140313 molecular sequestering activity 6/809 55/18639 0.109090909090909 2.51340600067423 0.0312877961442557 0.160592549342633 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/809 41/18639 0.121951219512195 2.80970183002201 0.0313383747430434 0.160592549342633 GO:0036408 histone H3K14 acetyltransferase activity 4/809 28/18639 0.142857142857143 3.29136500088292 0.0314951680018238 0.160592549342633 GO:0046966 nuclear thyroid hormone receptor binding 4/809 28/18639 0.142857142857143 3.29136500088292 0.0314951680018238 0.160592549342633 GO:0051019 mitogen-activated protein kinase binding 4/809 28/18639 0.142857142857143 3.29136500088292 0.0314951680018238 0.160592549342633 GO:0097110 scaffold protein binding 7/809 70/18639 0.1 2.30395550061805 0.0318022593706805 0.161318196496871 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 30/809 484/18639 0.0619834710743802 1.42807159129218 0.0323819361061873 0.163411935298749 GO:0004402 histone acetyltransferase activity 5/809 42/18639 0.119047619047619 2.74280416740244 0.0343481813011635 0.168673782630055 GO:0061775 cohesin loader activity 12/809 153/18639 0.0784313725490196 1.80702392205337 0.0346805417310642 0.168673782630055 GO:0015278 intracellularly gated calcium channel activity 3/809 17/18639 0.176470588235294 4.06580382462008 0.0351597298294666 0.168673782630055 GO:0031489 myosin V binding 3/809 17/18639 0.176470588235294 4.06580382462008 0.0351597298294666 0.168673782630055 GO:0032183 SUMO binding 3/809 17/18639 0.176470588235294 4.06580382462008 0.0351597298294666 0.168673782630055 GO:1990226 histone methyltransferase binding 3/809 17/18639 0.176470588235294 4.06580382462008 0.0351597298294666 0.168673782630055 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 4/809 29/18639 0.137931034482759 3.17786965602489 0.0353198421237602 0.168673782630055 GO:0010484 histone H3 acetyltransferase activity 4/809 29/18639 0.137931034482759 3.17786965602489 0.0353198421237602 0.168673782630055 GO:0035250 UDP-galactosyltransferase activity 4/809 29/18639 0.137931034482759 3.17786965602489 0.0353198421237602 0.168673782630055 GO:0043236 laminin binding 4/809 29/18639 0.137931034482759 3.17786965602489 0.0353198421237602 0.168673782630055 GO:0097472 cyclin-dependent protein kinase activity 4/809 29/18639 0.137931034482759 3.17786965602489 0.0353198421237602 0.168673782630055 GO:0042379 chemokine receptor binding 7/809 72/18639 0.0972222222222222 2.23995673671199 0.0363229431098628 0.172622142255125 GO:0030246 carbohydrate binding 19/809 280/18639 0.0678571428571429 1.56339837541939 0.0368080703378147 0.174082612853723 GO:0004386 helicase activity 12/809 155/18639 0.0774193548387097 1.78370748434946 0.0377509179747149 0.177683407198298 GO:0001216 DNA-binding transcription activator activity 30/809 491/18639 0.0610997963340122 1.4077121185039 0.0380424097536645 0.178198656214534 GO:0031624 ubiquitin conjugating enzyme binding 4/809 30/18639 0.133333333333333 3.07194066749073 0.0394012941129539 0.180251714656925 GO:0035925 mRNA 3'-UTR AU-rich region binding 4/809 30/18639 0.133333333333333 3.07194066749073 0.0394012941129539 0.180251714656925 GO:0043995 histone H4K5 acetyltransferase activity 4/809 30/18639 0.133333333333333 3.07194066749073 0.0394012941129539 0.180251714656925 GO:0043996 histone H4K8 acetyltransferase activity 4/809 30/18639 0.133333333333333 3.07194066749073 0.0394012941129539 0.180251714656925 GO:0043997 histone H4K12 acetyltransferase activity 4/809 30/18639 0.133333333333333 3.07194066749073 0.0394012941129539 0.180251714656925 GO:0070851 growth factor receptor binding 11/809 139/18639 0.079136690647482 1.82327413717975 0.0397355374113486 0.180935307561443 GO:0000400 four-way junction DNA binding 3/809 18/18639 0.166666666666667 3.83992583436341 0.0408671961078778 0.184373202717107 GO:1901611 phosphatidylglycerol binding 3/809 18/18639 0.166666666666667 3.83992583436341 0.0408671961078778 0.184373202717107 GO:0019210 kinase inhibitor activity 8/809 90/18639 0.0888888888888889 2.04796044499382 0.0415861330802717 0.186756074704523 GO:0070888 E-box binding 6/809 59/18639 0.101694915254237 2.34300559384886 0.0421291738761368 0.188330873172319 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 6/809 60/18639 0.1 2.30395550061805 0.0451655511809107 0.200986702755052 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 3/809 19/18639 0.157894736842105 3.63782447466007 0.0470101704765277 0.206380972630137 GO:0008301 DNA binding, bending 3/809 19/18639 0.157894736842105 3.63782447466007 0.0470101704765277 0.206380972630137 GO:1990380 K48-linked deubiquitinase activity 3/809 19/18639 0.157894736842105 3.63782447466007 0.0470101704765277 0.206380972630137 GO:0008378 galactosyltransferase activity 4/809 32/18639 0.125 2.87994437577256 0.048335894448828 0.210314847401789 GO:0070717 poly-purine tract binding 4/809 32/18639 0.125 2.87994437577256 0.048335894448828 0.210314847401789 GO:0051213 dioxygenase activity 8/809 93/18639 0.0860215053763441 1.98189720483273 0.0489030719946056 0.211841183551853 GO:0016410 N-acyltransferase activity 8/809 94/18639 0.0851063829787234 1.96081319201536 0.0515162183034518 0.219519814314226 GO:0042562 hormone binding 8/809 94/18639 0.0851063829787234 1.96081319201536 0.0515162183034518 0.219519814314226 GO:0061733 protein-lysine-acetyltransferase activity 5/809 47/18639 0.106382978723404 2.4510164900192 0.0520210387343213 0.219519814314226 GO:0061749 forked DNA-dependent helicase activity 5/809 47/18639 0.106382978723404 2.4510164900192 0.0520210387343213 0.219519814314226 GO:0140938 histone H3 methyltransferase activity 5/809 47/18639 0.106382978723404 2.4510164900192 0.0520210387343213 0.219519814314226 GO:1990518 single-stranded 3'-5' DNA helicase activity 5/809 47/18639 0.106382978723404 2.4510164900192 0.0520210387343213 0.219519814314226 GO:0019956 chemokine binding 4/809 33/18639 0.121212121212121 2.79267333408248 0.0531877549858257 0.223206395097366 GO:0016004 phospholipase activator activity 3/809 20/18639 0.15 3.45593325092707 0.0535786545943626 0.223206395097366 GO:0061608 nuclear import signal receptor activity 3/809 20/18639 0.15 3.45593325092707 0.0535786545943626 0.223206395097366 GO:0140713 histone chaperone activity 12/809 164/18639 0.0731707317073171 1.68582109801321 0.0539434025138822 0.223773690936825 GO:0035591 signaling adaptor activity 10/809 129/18639 0.0775193798449612 1.78601201598298 0.0543097429071753 0.224342777662973 GO:0009378 four-way junction helicase activity 5/809 48/18639 0.104166666666667 2.39995364647713 0.0560872440778657 0.228789216467627 GO:0036121 double-stranded DNA helicase activity 5/809 48/18639 0.104166666666667 2.39995364647713 0.0560872440778657 0.228789216467627 GO:0043138 3'-5' DNA helicase activity 5/809 48/18639 0.104166666666667 2.39995364647713 0.0560872440778657 0.228789216467627 GO:0004896 cytokine receptor activity 8/809 96/18639 0.0833333333333333 1.91996291718171 0.0570080374905456 0.231580368063254 GO:0008376 acetylgalactosaminyltransferase activity 4/809 34/18639 0.117647058823529 2.71053588308006 0.0582938909828699 0.234854811819875 GO:0052866 phosphatidylinositol phosphate phosphatase activity 4/809 34/18639 0.117647058823529 2.71053588308006 0.0582938909828699 0.234854811819875 GO:0008373 sialyltransferase activity 3/809 21/18639 0.142857142857143 3.29136500088292 0.0605610326664033 0.240135276963466 GO:0051010 microtubule plus-end binding 3/809 21/18639 0.142857142857143 3.29136500088292 0.0605610326664033 0.240135276963466 GO:0072542 protein phosphatase activator activity 3/809 21/18639 0.142857142857143 3.29136500088292 0.0605610326664033 0.240135276963466 GO:0004857 enzyme inhibitor activity 25/809 416/18639 0.0600961538461538 1.38458864219835 0.0635523371314602 0.240135276963466 GO:0000175 3'-5'-RNA exonuclease activity 4/809 35/18639 0.114285714285714 2.63309200070634 0.063651856679589 0.240135276963466 GO:0000510 H3-H4 histone complex chaperone activity 11/809 151/18639 0.0728476821192053 1.67837817925818 0.0647324448630323 0.240135276963466 GO:0140584 chromatin extrusion motor activity 11/809 151/18639 0.0728476821192053 1.67837817925818 0.0647324448630323 0.240135276963466 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 11/809 151/18639 0.0728476821192053 1.67837817925818 0.0647324448630323 0.240135276963466 GO:0140849 ATP-dependent H2AZ histone chaperone activity 11/809 151/18639 0.0728476821192053 1.67837817925818 0.0647324448630323 0.240135276963466 GO:0015616 DNA translocase activity 11/809 152/18639 0.0723684210526316 1.66733621755253 0.0671913392756602 0.240135276963466 GO:0140674 ATP-dependent histone chaperone activity 11/809 152/18639 0.0723684210526316 1.66733621755253 0.0671913392756602 0.240135276963466 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 2/809 10/18639 0.2 4.60791100123609 0.0671928596543407 0.240135276963466 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/809 10/18639 0.2 4.60791100123609 0.0671928596543407 0.240135276963466 GO:0031996 thioesterase binding 2/809 10/18639 0.2 4.60791100123609 0.0671928596543407 0.240135276963466 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 2/809 10/18639 0.2 4.60791100123609 0.0671928596543407 0.240135276963466 GO:0042975 peroxisome proliferator activated receptor binding 2/809 10/18639 0.2 4.60791100123609 0.0671928596543407 0.240135276963466 GO:0051864 histone H3K36 demethylase activity 2/809 10/18639 0.2 4.60791100123609 0.0671928596543407 0.240135276963466 GO:0070097 delta-catenin binding 2/809 10/18639 0.2 4.60791100123609 0.0671928596543407 0.240135276963466 GO:0070513 death domain binding 2/809 10/18639 0.2 4.60791100123609 0.0671928596543407 0.240135276963466 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 3/809 22/18639 0.136363636363636 3.14175750084279 0.067944302062186 0.240135276963466 GO:0032931 histone H3K56 acetyltransferase activity 3/809 22/18639 0.136363636363636 3.14175750084279 0.067944302062186 0.240135276963466 GO:0043992 histone H3K9 acetyltransferase activity 3/809 22/18639 0.136363636363636 3.14175750084279 0.067944302062186 0.240135276963466 GO:0043993 histone H3K18 acetyltransferase activity 3/809 22/18639 0.136363636363636 3.14175750084279 0.067944302062186 0.240135276963466 GO:0043994 histone H3K23 acetyltransferase activity 3/809 22/18639 0.136363636363636 3.14175750084279 0.067944302062186 0.240135276963466 GO:0043999 histone H2AK5 acetyltransferase activity 3/809 22/18639 0.136363636363636 3.14175750084279 0.067944302062186 0.240135276963466 GO:0044012 histone H2AK9 acetyltransferase activity 3/809 22/18639 0.136363636363636 3.14175750084279 0.067944302062186 0.240135276963466 GO:0044014 histone H2BK5 acetyltransferase activity 3/809 22/18639 0.136363636363636 3.14175750084279 0.067944302062186 0.240135276963466 GO:0044015 histone H2BK12 acetyltransferase activity 3/809 22/18639 0.136363636363636 3.14175750084279 0.067944302062186 0.240135276963466 GO:0044016 histone H3K4 acetyltransferase activity 3/809 22/18639 0.136363636363636 3.14175750084279 0.067944302062186 0.240135276963466 GO:0044017 histone H3K27 acetyltransferase activity 3/809 22/18639 0.136363636363636 3.14175750084279 0.067944302062186 0.240135276963466 GO:0044018 histone H3K36 acetyltransferase activity 3/809 22/18639 0.136363636363636 3.14175750084279 0.067944302062186 0.240135276963466 GO:0046972 histone H4K16 acetyltransferase activity 3/809 22/18639 0.136363636363636 3.14175750084279 0.067944302062186 0.240135276963466 GO:0070034 telomerase RNA binding 3/809 22/18639 0.136363636363636 3.14175750084279 0.067944302062186 0.240135276963466 GO:0140908 histone H3K122 acetyltransferase activity 3/809 22/18639 0.136363636363636 3.14175750084279 0.067944302062186 0.240135276963466 GO:0061134 peptidase regulator activity 15/809 226/18639 0.0663716814159292 1.52917400483499 0.0682425750260162 0.240321873922553 GO:0030165 PDZ domain binding 7/809 83/18639 0.0843373493975904 1.94309500052124 0.0686384865935527 0.240760009095257 GO:0000993 RNA polymerase II complex binding 4/809 36/18639 0.111111111111111 2.55995055624227 0.0692585560121528 0.240760009095257 GO:0044390 ubiquitin-like protein conjugating enzyme binding 4/809 36/18639 0.111111111111111 2.55995055624227 0.0692585560121528 0.240760009095257 GO:0005048 signal sequence binding 5/809 51/18639 0.0980392156862745 2.25877990256671 0.0693506869916879 0.240760009095257 GO:0051015 actin filament binding 14/809 209/18639 0.0669856459330144 1.54331947409821 0.0718572775712259 0.248580476120955 GO:0019838 growth factor binding 10/809 136/18639 0.0735294117647059 1.69408492692503 0.0721758141130396 0.248803246537556 GO:0005548 phospholipid transporter activity 6/809 68/18639 0.0882352941176471 2.03290191231004 0.0742893080509712 0.254298016020632 GO:1990841 promoter-specific chromatin binding 6/809 68/18639 0.0882352941176471 2.03290191231004 0.0742893080509712 0.254298016020632 GO:0005158 insulin receptor binding 3/809 23/18639 0.130434782608696 3.00515934863223 0.0757142839244149 0.255600979179318 GO:0044013 histone H2B acetyltransferase activity 3/809 23/18639 0.130434782608696 3.00515934863223 0.0757142839244149 0.255600979179318 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 3/809 23/18639 0.130434782608696 3.00515934863223 0.0757142839244149 0.255600979179318 GO:0070577 lysine-acetylated histone binding 3/809 23/18639 0.130434782608696 3.00515934863223 0.0757142839244149 0.255600979179318 GO:0008080 N-acetyltransferase activity 6/809 69/18639 0.0869565217391304 2.00343956575482 0.0785368578233433 0.256225265238547 GO:0005246 calcium channel regulator activity 5/809 53/18639 0.0943396226415094 2.17354292511137 0.079071844534727 0.256225265238547 GO:0017046 peptide hormone binding 5/809 53/18639 0.0943396226415094 2.17354292511137 0.079071844534727 0.256225265238547 GO:0034212 protein N-acetyltransferase activity 5/809 53/18639 0.0943396226415094 2.17354292511137 0.079071844534727 0.256225265238547 GO:0001851 complement component C3b binding 2/809 11/18639 0.181818181818182 4.18901000112372 0.079825031560528 0.256225265238547 GO:0002162 dystroglycan binding 2/809 11/18639 0.181818181818182 4.18901000112372 0.079825031560528 0.256225265238547 GO:0008526 phosphatidylinositol transfer activity 2/809 11/18639 0.181818181818182 4.18901000112372 0.079825031560528 0.256225265238547 GO:0032050 clathrin heavy chain binding 2/809 11/18639 0.181818181818182 4.18901000112372 0.079825031560528 0.256225265238547 GO:0034056 estrogen response element binding 2/809 11/18639 0.181818181818182 4.18901000112372 0.079825031560528 0.256225265238547 GO:0034713 type I transforming growth factor beta receptor binding 2/809 11/18639 0.181818181818182 4.18901000112372 0.079825031560528 0.256225265238547 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 2/809 11/18639 0.181818181818182 4.18901000112372 0.079825031560528 0.256225265238547 GO:0042608 T cell receptor binding 2/809 11/18639 0.181818181818182 4.18901000112372 0.079825031560528 0.256225265238547 GO:0140031 phosphorylation-dependent protein binding 2/809 11/18639 0.181818181818182 4.18901000112372 0.079825031560528 0.256225265238547 GO:0140537 transcription regulator activator activity 2/809 11/18639 0.181818181818182 4.18901000112372 0.079825031560528 0.256225265238547 GO:0180030 inositol phosphate kinase activity 2/809 11/18639 0.181818181818182 4.18901000112372 0.079825031560528 0.256225265238547 GO:0030295 protein kinase activator activity 10/809 139/18639 0.0719424460431655 1.65752194289068 0.0808439785042179 0.258647892011861 GO:0043531 ADP binding 4/809 38/18639 0.105263157894737 2.42521631644005 0.0812027614341545 0.258949522619014 GO:0016278 lysine N-methyltransferase activity 6/809 70/18639 0.0857142857142857 1.97481900052975 0.0829182264282805 0.258974268389525 GO:0140658 ATP-dependent chromatin remodeler activity 11/809 158/18639 0.069620253164557 1.60401965232902 0.0832027371674353 0.258974268389525 GO:0008081 phosphoric diester hydrolase activity 7/809 87/18639 0.0804597701149425 1.85375729934785 0.0836253537068272 0.258974268389525 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/809 24/18639 0.125 2.87994437577256 0.0838558151986512 0.258974268389525 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/809 24/18639 0.125 2.87994437577256 0.0838558151986512 0.258974268389525 GO:0043998 histone H2A acetyltransferase activity 3/809 24/18639 0.125 2.87994437577256 0.0838558151986512 0.258974268389525 GO:0050699 WW domain binding 3/809 24/18639 0.125 2.87994437577256 0.0838558151986512 0.258974268389525 GO:0060229 lipase activator activity 3/809 24/18639 0.125 2.87994437577256 0.0838558151986512 0.258974268389525 GO:0070300 phosphatidic acid binding 3/809 24/18639 0.125 2.87994437577256 0.0838558151986512 0.258974268389525 GO:0140033 acetylation-dependent protein binding 3/809 24/18639 0.125 2.87994437577256 0.0838558151986512 0.258974268389525 GO:0016758 hexosyltransferase activity 13/809 197/18639 0.065989847715736 1.52037672629617 0.0881583012107966 0.271405587689842 GO:0003689 DNA clamp loader activity 11/809 160/18639 0.06875 1.58396940667491 0.0890228466373991 0.273208046576845 GO:0008013 beta-catenin binding 8/809 106/18639 0.0754716981132075 1.73883434008909 0.0898791225783173 0.273762639316354 GO:0004709 MAP kinase kinase kinase activity 3/809 25/18639 0.12 2.76474660074166 0.092352923422979 0.273762639316354 GO:0017025 TBP-class protein binding 3/809 25/18639 0.12 2.76474660074166 0.092352923422979 0.273762639316354 GO:0042974 nuclear retinoic acid receptor binding 3/809 25/18639 0.12 2.76474660074166 0.092352923422979 0.273762639316354 GO:0005078 MAP-kinase scaffold activity 2/809 12/18639 0.166666666666667 3.83992583436341 0.0931184462638876 0.273762639316354 GO:0005095 GTPase inhibitor activity 2/809 12/18639 0.166666666666667 3.83992583436341 0.0931184462638876 0.273762639316354 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/809 12/18639 0.166666666666667 3.83992583436341 0.0931184462638876 0.273762639316354 GO:0035197 siRNA binding 2/809 12/18639 0.166666666666667 3.83992583436341 0.0931184462638876 0.273762639316354 GO:0070008 serine-type exopeptidase activity 2/809 12/18639 0.166666666666667 3.83992583436341 0.0931184462638876 0.273762639316354 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 2/809 12/18639 0.166666666666667 3.83992583436341 0.0931184462638876 0.273762639316354 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 2/809 12/18639 0.166666666666667 3.83992583436341 0.0931184462638876 0.273762639316354 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 2/809 12/18639 0.166666666666667 3.83992583436341 0.0931184462638876 0.273762639316354 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 2/809 12/18639 0.166666666666667 3.83992583436341 0.0931184462638876 0.273762639316354 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 2/809 12/18639 0.166666666666667 3.83992583436341 0.0931184462638876 0.273762639316354 GO:0030331 nuclear estrogen receptor binding 4/809 40/18639 0.1 2.30395550061805 0.0940902652933529 0.275791526114349 GO:0043539 protein serine/threonine kinase activator activity 6/809 73/18639 0.0821917808219178 1.8936620553025 0.096856038678316 0.283050930943497 GO:0061650 ubiquitin-like protein conjugating enzyme activity 4/809 41/18639 0.0975609756097561 2.24776146401761 0.100874253460954 0.290510313296401 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/809 26/18639 0.115384615384615 2.65841019302082 0.101188985530207 0.290510313296401 GO:0005160 transforming growth factor beta receptor binding 3/809 26/18639 0.115384615384615 2.65841019302082 0.101188985530207 0.290510313296401 GO:0008143 poly(A) binding 3/809 26/18639 0.115384615384615 2.65841019302082 0.101188985530207 0.290510313296401 GO:0015145 monosaccharide transmembrane transporter activity 3/809 26/18639 0.115384615384615 2.65841019302082 0.101188985530207 0.290510313296401 GO:0030247 polysaccharide binding 3/809 26/18639 0.115384615384615 2.65841019302082 0.101188985530207 0.290510313296401 GO:0017116 single-stranded DNA helicase activity 5/809 58/18639 0.0862068965517241 1.98616853501556 0.106351664757023 0.303609380103922 GO:0140333 glycerophospholipid flippase activity 2/809 13/18639 0.153846153846154 3.54454692402776 0.106992069597399 0.303609380103922 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 2/809 13/18639 0.153846153846154 3.54454692402776 0.106992069597399 0.303609380103922 GO:0140852 histone ubiquitin ligase activity 2/809 13/18639 0.153846153846154 3.54454692402776 0.106992069597399 0.303609380103922 GO:0043175 RNA polymerase core enzyme binding 4/809 42/18639 0.0952380952380952 2.19424333392195 0.107876997898826 0.304356141045968 GO:0051879 Hsp90 protein binding 4/809 42/18639 0.0952380952380952 2.19424333392195 0.107876997898826 0.304356141045968 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 3/809 27/18639 0.111111111111111 2.55995055624227 0.110346871833975 0.309540365402468 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/809 27/18639 0.111111111111111 2.55995055624227 0.110346871833975 0.309540365402468 GO:0008234 cysteine-type peptidase activity 12/809 187/18639 0.0641711229946524 1.47847411804367 0.114573572987327 0.320478651298836 GO:0008375 acetylglucosaminyltransferase activity 4/809 43/18639 0.0930232558139535 2.14321441917958 0.115091973045938 0.321011514564026 GO:0031072 heat shock protein binding 9/809 131/18639 0.0687022900763359 1.58287019126431 0.116569667236961 0.324209387002798 GO:0005516 calmodulin binding 13/809 207/18639 0.0628019323671498 1.44692857526737 0.117014984059777 0.324525975621874 GO:0140597 protein carrier chaperone 12/809 188/18639 0.0638297872340425 1.47060989401152 0.117858210079846 0.324691133530215 GO:0001098 basal transcription machinery binding 5/809 60/18639 0.0833333333333333 1.91996291718171 0.118401159009486 0.324691133530215 GO:0001099 basal RNA polymerase II transcription machinery binding 5/809 60/18639 0.0833333333333333 1.91996291718171 0.118401159009486 0.324691133530215 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 5/809 60/18639 0.0833333333333333 1.91996291718171 0.118401159009486 0.324691133530215 GO:0051119 sugar transmembrane transporter activity 3/809 28/18639 0.107142857142857 2.46852375066219 0.119809076293833 0.326433674232791 GO:0004705 JUN kinase activity 2/809 14/18639 0.142857142857143 3.29136500088292 0.121370640879199 0.326433674232791 GO:0005545 1-phosphatidylinositol binding 2/809 14/18639 0.142857142857143 3.29136500088292 0.121370640879199 0.326433674232791 GO:0019992 diacylglycerol binding 2/809 14/18639 0.142857142857143 3.29136500088292 0.121370640879199 0.326433674232791 GO:0034236 protein kinase A catalytic subunit binding 2/809 14/18639 0.142857142857143 3.29136500088292 0.121370640879199 0.326433674232791 GO:0046030 inositol trisphosphate phosphatase activity 2/809 14/18639 0.142857142857143 3.29136500088292 0.121370640879199 0.326433674232791 GO:1901612 cardiolipin binding 2/809 14/18639 0.142857142857143 3.29136500088292 0.121370640879199 0.326433674232791 GO:0016407 acetyltransferase activity 7/809 96/18639 0.0729166666666667 1.67996755253399 0.12359221180069 0.331498014665413 GO:0046982 protein heterodimerization activity 21/809 369/18639 0.0569105691056911 1.3111941873436 0.125497413854028 0.335688437604081 GO:0008094 ATP-dependent activity, acting on DNA 13/809 210/18639 0.0619047619047619 1.42625816704927 0.126628192099416 0.3377901909137 GO:0008186 ATP-dependent activity, acting on RNA 6/809 79/18639 0.0759493670886076 1.74983962072257 0.128179201934261 0.340998474710984 GO:0099604 ligand-gated calcium channel activity 3/809 29/18639 0.103448275862069 2.38340224201867 0.129557834082687 0.342468083242301 GO:0106222 lncRNA binding 3/809 29/18639 0.103448275862069 2.38340224201867 0.129557834082687 0.342468083242301 GO:0008009 chemokine activity 4/809 45/18639 0.0888888888888889 2.04796044499382 0.130130875348454 0.342468083242301 GO:0140303 intramembrane lipid transporter activity 4/809 45/18639 0.0888888888888889 2.04796044499382 0.130130875348454 0.342468083242301 GO:0008170 N-methyltransferase activity 7/809 98/18639 0.0714285714285714 1.64568250044146 0.133600026644491 0.350655297814897 GO:0015929 hexosaminidase activity 2/809 15/18639 0.133333333333333 3.07194066749073 0.136184325394998 0.352710197253182 GO:0031386 protein tag activity 2/809 15/18639 0.133333333333333 3.07194066749073 0.136184325394998 0.352710197253182 GO:0050780 dopamine receptor binding 2/809 15/18639 0.133333333333333 3.07194066749073 0.136184325394998 0.352710197253182 GO:0120283 protein serine/threonine kinase binding 2/809 15/18639 0.133333333333333 3.07194066749073 0.136184325394998 0.352710197253182 GO:0141047 molecular tag activity 2/809 15/18639 0.133333333333333 3.07194066749073 0.136184325394998 0.352710197253182 GO:0044325 transmembrane transporter binding 9/809 136/18639 0.0661764705882353 1.52467643423253 0.137430705300004 0.35499910419183 GO:0030276 clathrin binding 4/809 46/18639 0.0869565217391304 2.00343956575482 0.13794022094996 0.355377569236871 GO:0001968 fibronectin binding 3/809 30/18639 0.1 2.30395550061805 0.139575227412658 0.356773231428178 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 3/809 30/18639 0.1 2.30395550061805 0.139575227412658 0.356773231428178 GO:0031210 phosphatidylcholine binding 3/809 30/18639 0.1 2.30395550061805 0.139575227412658 0.356773231428178 GO:0016887 ATP hydrolysis activity 23/809 417/18639 0.0551558752997602 1.27076682288286 0.14300334711312 0.364584054228501 GO:0140097 catalytic activity, acting on DNA 19/809 336/18639 0.056547619047619 1.30283197951616 0.145433050020042 0.369815470050964 GO:0005164 tumor necrosis factor receptor binding 3/809 31/18639 0.0967741935483871 2.22963435543682 0.149843280512164 0.378034821439424 GO:0070325 lipoprotein particle receptor binding 3/809 31/18639 0.0967741935483871 2.22963435543682 0.149843280512164 0.378034821439424 GO:0140767 enzyme-substrate adaptor activity 9/809 139/18639 0.0647482014388489 1.49176974860161 0.150811335791226 0.378034821439424 GO:0004707 MAP kinase activity 2/809 16/18639 0.125 2.87994437577256 0.151368386112619 0.378034821439424 GO:0005159 insulin-like growth factor receptor binding 2/809 16/18639 0.125 2.87994437577256 0.151368386112619 0.378034821439424 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/809 16/18639 0.125 2.87994437577256 0.151368386112619 0.378034821439424 GO:0140327 flippase activity 2/809 16/18639 0.125 2.87994437577256 0.151368386112619 0.378034821439424 GO:0001217 DNA-binding transcription repressor activity 16/809 278/18639 0.0575539568345324 1.32601755431255 0.153942923972288 0.38290447233179 GO:0038187 pattern recognition receptor activity 4/809 48/18639 0.0833333333333333 1.91996291718171 0.154100472010955 0.38290447233179 GO:0004860 protein kinase inhibitor activity 6/809 84/18639 0.0714285714285714 1.64568250044146 0.157544190043512 0.390470283677464 GO:0140142 nucleocytoplasmic carrier activity 3/809 32/18639 0.09375 2.15995828182942 0.160344044587682 0.396406110230658 GO:0042054 histone methyltransferase activity 5/809 67/18639 0.0746268656716418 1.71936977658063 0.165186267186022 0.407348502708099 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 2/809 17/18639 0.117647058823529 2.71053588308006 0.16686287361704 0.407378437084992 GO:0008429 phosphatidylethanolamine binding 2/809 17/18639 0.117647058823529 2.71053588308006 0.16686287361704 0.407378437084992 GO:0046965 nuclear retinoid X receptor binding 2/809 17/18639 0.117647058823529 2.71053588308006 0.16686287361704 0.407378437084992 GO:0070403 NAD+ binding 2/809 17/18639 0.117647058823529 2.71053588308006 0.16686287361704 0.407378437084992 GO:0003730 mRNA 3'-UTR binding 15/809 262/18639 0.0572519083969466 1.31905849272026 0.168126379493647 0.40944210329423 GO:0032813 tumor necrosis factor receptor superfamily binding 4/809 50/18639 0.08 1.84316440049444 0.17092967232535 0.413499803465091 GO:0071889 14-3-3 protein binding 3/809 33/18639 0.0909090909090909 2.09450500056186 0.171059673547867 0.413499803465091 GO:0140311 protein sequestering activity 3/809 33/18639 0.0909090909090909 2.09450500056186 0.171059673547867 0.413499803465091 GO:0030145 manganese ion binding 5/809 68/18639 0.0735294117647059 1.69408492692503 0.172400311561819 0.414692641324376 GO:0032934 sterol binding 5/809 68/18639 0.0735294117647059 1.69408492692503 0.172400311561819 0.414692641324376 GO:0019955 cytokine binding 9/809 144/18639 0.0625 1.43997218788628 0.174473784559928 0.418651556578847 GO:0016279 protein-lysine N-methyltransferase activity 5/809 69/18639 0.072463768115942 1.66953297146235 0.179733393885138 0.428722959967063 GO:1901981 phosphatidylinositol phosphate binding 11/809 185/18639 0.0594594594594595 1.36991948685397 0.181637421748747 0.428722959967063 GO:0030332 cyclin binding 3/809 34/18639 0.0882352941176471 2.03290191231004 0.181972491215447 0.428722959967063 GO:0004706 JUN kinase kinase kinase activity 2/809 18/18639 0.111111111111111 2.55995055624227 0.182612333305685 0.428722959967063 GO:0008525 phosphatidylcholine transporter activity 2/809 18/18639 0.111111111111111 2.55995055624227 0.182612333305685 0.428722959967063 GO:0031690 adrenergic receptor binding 2/809 18/18639 0.111111111111111 2.55995055624227 0.182612333305685 0.428722959967063 GO:0050811 GABA receptor binding 2/809 18/18639 0.111111111111111 2.55995055624227 0.182612333305685 0.428722959967063 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 2/809 18/18639 0.111111111111111 2.55995055624227 0.182612333305685 0.428722959967063 GO:0070628 proteasome binding 2/809 18/18639 0.111111111111111 2.55995055624227 0.182612333305685 0.428722959967063 GO:0016782 transferase activity, transferring sulphur-containing groups 5/809 70/18639 0.0714285714285714 1.64568250044146 0.187180714458742 0.438396936495475 GO:0005496 steroid binding 7/809 108/18639 0.0648148148148148 1.49330449114133 0.189157018424479 0.441327589699782 GO:0015085 calcium ion transmembrane transporter activity 9/809 147/18639 0.0612244897959184 1.4105850003784 0.189440227597626 0.441327589699782 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 15/809 268/18639 0.0559701492537313 1.28952733243547 0.189784387398987 0.441327589699782 GO:0005154 epidermal growth factor receptor binding 3/809 35/18639 0.0857142857142857 1.97481900052975 0.193065050703184 0.445779916600041 GO:0043015 gamma-tubulin binding 3/809 35/18639 0.0857142857142857 1.97481900052975 0.193065050703184 0.445779916600041 GO:0061631 ubiquitin conjugating enzyme activity 3/809 35/18639 0.0857142857142857 1.97481900052975 0.193065050703184 0.445779916600041 GO:0140104 molecular carrier activity 14/809 249/18639 0.0562248995983936 1.29539666701416 0.19546070051837 0.449989937095044 GO:0005544 calcium-dependent phospholipid binding 4/809 53/18639 0.0754716981132075 1.73883434008909 0.197283896496333 0.449989937095044 GO:0008146 sulfotransferase activity 4/809 53/18639 0.0754716981132075 1.73883434008909 0.197283896496333 0.449989937095044 GO:0140296 general transcription initiation factor binding 4/809 53/18639 0.0754716981132075 1.73883434008909 0.197283896496333 0.449989937095044 GO:0022821 solute:potassium antiporter activity 2/809 19/18639 0.105263157894737 2.42521631644005 0.198565528932644 0.449989937095044 GO:0030506 ankyrin binding 2/809 19/18639 0.105263157894737 2.42521631644005 0.198565528932644 0.449989937095044 GO:0042800 histone H3K4 methyltransferase activity 2/809 19/18639 0.105263157894737 2.42521631644005 0.198565528932644 0.449989937095044 GO:0140036 ubiquitin-modified protein reader activity 2/809 19/18639 0.105263157894737 2.42521631644005 0.198565528932644 0.449989937095044 GO:0015485 cholesterol binding 4/809 54/18639 0.0740740740740741 1.70663370416152 0.206331259009749 0.466508781918116 GO:0015095 magnesium ion transmembrane transporter activity 2/809 20/18639 0.1 2.30395550061805 0.214675181636898 0.482034410143402 GO:0042288 MHC class I protein binding 2/809 20/18639 0.1 2.30395550061805 0.214675181636898 0.482034410143402 GO:0052745 inositol phosphate phosphatase activity 2/809 20/18639 0.1 2.30395550061805 0.214675181636898 0.482034410143402 GO:0005126 cytokine receptor binding 15/809 275/18639 0.0545454545454545 1.25670300033712 0.216645351274121 0.48534507756834 GO:0003678 DNA helicase activity 5/809 74/18639 0.0675675675675676 1.55672668960679 0.218013751268199 0.487295576464765 GO:0001664 G protein-coupled receptor binding 16/809 297/18639 0.0538720538720539 1.2411881484811 0.221177368807487 0.493240647067267 GO:0019212 phosphatase inhibitor activity 4/809 56/18639 0.0714285714285714 1.64568250044146 0.224769354904649 0.500111814662845 GO:0000146 microfilament motor activity 3/809 38/18639 0.0789473684210526 1.81891223733004 0.227251200358773 0.504487358619588 GO:0008276 protein methyltransferase activity 6/809 95/18639 0.0631578947368421 1.45512978986403 0.230857789517766 0.507974991994343 GO:0001846 opsonin binding 2/809 21/18639 0.0952380952380952 2.19424333392195 0.230897723633792 0.507974991994343 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/809 21/18639 0.0952380952380952 2.19424333392195 0.230897723633792 0.507974991994343 GO:0140312 cargo adaptor activity 2/809 21/18639 0.0952380952380952 2.19424333392195 0.230897723633792 0.507974991994343 GO:0017022 myosin binding 5/809 76/18639 0.0657894736842105 1.51576019777503 0.233985953474742 0.512465880205307 GO:0051536 iron-sulfur cluster binding 5/809 76/18639 0.0657894736842105 1.51576019777503 0.233985953474742 0.512465880205307 GO:0002020 protease binding 8/809 136/18639 0.0588235294117647 1.35526794154003 0.238835843878201 0.520885856534462 GO:0000217 DNA secondary structure binding 3/809 39/18639 0.0769230769230769 1.77227346201388 0.23889453481509 0.520885856534462 GO:0003724 RNA helicase activity 5/809 77/18639 0.0649350649350649 1.49607500040133 0.242093087974062 0.525519142187598 GO:0051540 metal cluster binding 5/809 77/18639 0.0649350649350649 1.49607500040133 0.242093087974062 0.525519142187598 GO:0008408 3'-5' exonuclease activity 4/809 58/18639 0.0689655172413793 1.58893482801245 0.243609325564217 0.527640552494177 GO:1990782 protein tyrosine kinase binding 7/809 117/18639 0.0598290598290598 1.37843491489969 0.245788600816462 0.529544882733792 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/809 22/18639 0.0909090909090909 2.09450500056186 0.247193065790953 0.529544882733792 GO:0031683 G-protein beta/gamma-subunit complex binding 2/809 22/18639 0.0909090909090909 2.09450500056186 0.247193065790953 0.529544882733792 GO:0061133 endopeptidase activator activity 2/809 22/18639 0.0909090909090909 2.09450500056186 0.247193065790953 0.529544882733792 GO:0140035 ubiquitin-like protein reader activity 2/809 22/18639 0.0909090909090909 2.09450500056186 0.247193065790953 0.529544882733792 GO:0004177 aminopeptidase activity 3/809 40/18639 0.075 1.72796662546354 0.250635421533069 0.532260472192787 GO:0015144 carbohydrate transmembrane transporter activity 3/809 40/18639 0.075 1.72796662546354 0.250635421533069 0.532260472192787 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/809 40/18639 0.075 1.72796662546354 0.250635421533069 0.532260472192787 GO:0050997 quaternary ammonium group binding 3/809 40/18639 0.075 1.72796662546354 0.250635421533069 0.532260472192787 GO:0001786 phosphatidylserine binding 4/809 59/18639 0.0677966101694915 1.56200372923257 0.253159226209582 0.535297802287648 GO:0031593 polyubiquitin modification-dependent protein binding 4/809 59/18639 0.0677966101694915 1.56200372923257 0.253159226209582 0.535297802287648 GO:0042287 MHC protein binding 3/809 41/18639 0.0731707317073171 1.68582109801321 0.262458671644026 0.552441898082072 GO:0016849 phosphorus-oxygen lyase activity 2/809 23/18639 0.0869565217391304 2.00343956575482 0.263524378349671 0.552441898082072 GO:0031681 G-protein beta-subunit binding 2/809 23/18639 0.0869565217391304 2.00343956575482 0.263524378349671 0.552441898082072 GO:0043274 phospholipase binding 2/809 23/18639 0.0869565217391304 2.00343956575482 0.263524378349671 0.552441898082072 GO:0019905 syntaxin binding 4/809 61/18639 0.0655737704918033 1.51079049220856 0.272477975652216 0.568820552503556 GO:0004540 RNA nuclease activity 7/809 121/18639 0.0578512396694215 1.33286681853937 0.272499324948078 0.568820552503556 GO:0001618 virus receptor activity 5/809 81/18639 0.0617283950617284 1.42219475346793 0.275208563702394 0.573253582690732 GO:0061135 endopeptidase regulator activity 10/809 184/18639 0.0543478260869565 1.25214972859676 0.278173147700009 0.578018709967865 GO:0015149 hexose transmembrane transporter activity 2/809 24/18639 0.0833333333333333 1.91996291718171 0.279857884090672 0.578018709967865 GO:0019957 C-C chemokine binding 2/809 24/18639 0.0833333333333333 1.91996291718171 0.279857884090672 0.578018709967865 GO:0055056 D-glucose transmembrane transporter activity 2/809 24/18639 0.0833333333333333 1.91996291718171 0.279857884090672 0.578018709967865 GO:0140272 exogenous protein binding 5/809 82/18639 0.0609756097560976 1.404850915011 0.283633574462799 0.584583725050695 GO:0004712 protein serine/threonine/tyrosine kinase activity 3/809 43/18639 0.0697674418604651 1.60741081438468 0.286293889367812 0.588827138006487 GO:0001848 complement binding 2/809 25/18639 0.08 1.84316440049444 0.296162663279168 0.604048431979802 GO:0008483 transaminase activity 2/809 25/18639 0.08 1.84316440049444 0.296162663279168 0.604048431979802 GO:0017056 structural constituent of nuclear pore 2/809 25/18639 0.08 1.84316440049444 0.296162663279168 0.604048431979802 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/809 25/18639 0.08 1.84316440049444 0.296162663279168 0.604048431979802 GO:0001046 core promoter sequence-specific DNA binding 3/809 44/18639 0.0681818181818182 1.5708787504214 0.298277906746449 0.607097860093085 GO:0004527 exonuclease activity 5/809 84/18639 0.0595238095238095 1.37140208370122 0.300623523215412 0.610602550265328 GO:0046915 transition metal ion transmembrane transporter activity 3/809 45/18639 0.0666666666666667 1.53597033374536 0.310288408989163 0.620715405005358 GO:0051539 4 iron, 4 sulfur cluster binding 3/809 45/18639 0.0666666666666667 1.53597033374536 0.310288408989163 0.620715405005358 GO:0038024 cargo receptor activity 4/809 65/18639 0.0615384615384615 1.41781876961111 0.311769336925665 0.620715405005358 GO:0001637 G protein-coupled chemoattractant receptor activity 2/809 26/18639 0.0769230769230769 1.77227346201388 0.312410469758247 0.620715405005358 GO:0004435 phosphatidylinositol phospholipase C activity 2/809 26/18639 0.0769230769230769 1.77227346201388 0.312410469758247 0.620715405005358 GO:0004950 chemokine receptor activity 2/809 26/18639 0.0769230769230769 1.77227346201388 0.312410469758247 0.620715405005358 GO:0043548 phosphatidylinositol 3-kinase binding 2/809 26/18639 0.0769230769230769 1.77227346201388 0.312410469758247 0.620715405005358 GO:0050750 low-density lipoprotein particle receptor binding 2/809 26/18639 0.0769230769230769 1.77227346201388 0.312410469758247 0.620715405005358 GO:0070006 metalloaminopeptidase activity 2/809 26/18639 0.0769230769230769 1.77227346201388 0.312410469758247 0.620715405005358 GO:0120014 phospholipid transfer activity 2/809 26/18639 0.0769230769230769 1.77227346201388 0.312410469758247 0.620715405005358 GO:0000149 SNARE binding 6/809 106/18639 0.0566037735849057 1.30412575506682 0.312576807627826 0.620715405005358 GO:0030291 protein serine/threonine kinase inhibitor activity 3/809 46/18639 0.0652173913043478 1.50257967431612 0.322312701177945 0.638753308609733 GO:0001671 ATPase activator activity 2/809 27/18639 0.0740740740740741 1.70663370416152 0.328575557592189 0.647234347852623 GO:0008266 poly(U) RNA binding 2/809 27/18639 0.0740740740740741 1.70663370416152 0.328575557592189 0.647234347852623 GO:0035255 ionotropic glutamate receptor binding 2/809 27/18639 0.0740740740740741 1.70663370416152 0.328575557592189 0.647234347852623 GO:0005504 fatty acid binding 3/809 47/18639 0.0638297872340425 1.47060989401152 0.334338610143495 0.648554103321461 GO:0043495 protein-membrane adaptor activity 3/809 47/18639 0.0638297872340425 1.47060989401152 0.334338610143495 0.648554103321461 GO:0004197 cysteine-type endopeptidase activity 5/809 88/18639 0.0568181818181818 1.30906562535116 0.335024832743155 0.648554103321461 GO:0005262 calcium channel activity 7/809 131/18639 0.0534351145038168 1.23112125987224 0.342026990079026 0.648554103321461 GO:0003823 antigen binding 9/809 174/18639 0.0517241379310345 1.19170112100933 0.343483930444144 0.648554103321461 GO:0045499 chemorepellent activity 2/809 28/18639 0.0714285714285714 1.64568250044146 0.344634517692063 0.648554103321461 GO:0046625 sphingolipid binding 2/809 28/18639 0.0714285714285714 1.64568250044146 0.344634517692063 0.648554103321461 GO:0050698 proteoglycan sulfotransferase activity 2/809 28/18639 0.0714285714285714 1.64568250044146 0.344634517692063 0.648554103321461 GO:0051537 2 iron, 2 sulfur cluster binding 2/809 28/18639 0.0714285714285714 1.64568250044146 0.344634517692063 0.648554103321461 GO:0097718 disordered domain specific binding 2/809 28/18639 0.0714285714285714 1.64568250044146 0.344634517692063 0.648554103321461 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/809 48/18639 0.0625 1.43997218788628 0.346354486018998 0.648554103321461 GO:0002039 p53 binding 4/809 69/18639 0.0579710144927536 1.33562637716988 0.351530590222819 0.648554103321461 GO:0035254 glutamate receptor binding 3/809 49/18639 0.0612244897959184 1.4105850003784 0.358349201691845 0.648554103321461 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0004955 prostaglandin receptor activity 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0005031 tumor necrosis factor receptor activity 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0005131 growth hormone receptor binding 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0005381 iron ion transmembrane transporter activity 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0005522 profilin binding 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0008140 cAMP response element binding protein binding 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0015187 glycine transmembrane transporter activity 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0015643 toxic substance binding 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0030957 Tat protein binding 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0031434 mitogen-activated protein kinase kinase binding 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0035256 G protein-coupled glutamate receptor binding 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0035374 chondroitin sulfate binding 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0043121 neurotrophin binding 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0043208 glycosphingolipid binding 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0050308 sugar-phosphatase activity 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0050815 phosphoserine residue binding 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0098505 G-rich strand telomeric DNA binding 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0099122 RNA polymerase II C-terminal domain binding 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0140999 histone H3K4 trimethyltransferase activity 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:1990763 arrestin family protein binding 1/809 10/18639 0.1 2.30395550061805 0.358436337922118 0.648554103321461 GO:0005539 glycosaminoglycan binding 12/809 242/18639 0.0495867768595041 1.14245727303374 0.359946403876403 0.648554103321461 GO:0003785 actin monomer binding 2/809 29/18639 0.0689655172413793 1.58893482801245 0.36056612388535 0.648554103321461 GO:0004629 phospholipase C activity 2/809 29/18639 0.0689655172413793 1.58893482801245 0.36056612388535 0.648554103321461 GO:0072341 modified amino acid binding 5/809 91/18639 0.0549450549450549 1.2659096157242 0.361043908386309 0.648554103321461 GO:0003924 GTPase activity 16/809 331/18639 0.0483383685800604 1.11369450180933 0.365237944239843 0.654886350569243 GO:0043178 alcohol binding 5/809 92/18639 0.0543478260869565 1.25214972859676 0.369733962612698 0.655433659824182 GO:0052689 carboxylic ester hydrolase activity 5/809 92/18639 0.0543478260869565 1.25214972859676 0.369733962612698 0.655433659824182 GO:0008187 poly-pyrimidine tract binding 2/809 30/18639 0.0666666666666667 1.53597033374536 0.376351187919114 0.655433659824182 GO:0016769 transferase activity, transferring nitrogenous groups 2/809 30/18639 0.0666666666666667 1.53597033374536 0.376351187919114 0.655433659824182 GO:0005010 insulin-like growth factor receptor activity 3/809 51/18639 0.0588235294117647 1.35526794154003 0.382233241501129 0.655433659824182 GO:0030544 Hsp70 protein binding 3/809 51/18639 0.0588235294117647 1.35526794154003 0.382233241501129 0.655433659824182 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0003953 NAD+ nucleosidase activity 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0004016 adenylate cyclase activity 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0004954 prostanoid receptor activity 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0005114 type II transforming growth factor beta receptor binding 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0005536 D-glucose binding 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0008432 JUN kinase binding 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0019203 carbohydrate phosphatase activity 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0019864 IgG binding 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0032794 GTPase activating protein binding 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0034511 U3 snoRNA binding 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0035252 UDP-xylosyltransferase activity 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0042285 xylosyltransferase activity 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0043522 leucine zipper domain binding 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0045294 alpha-catenin binding 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0048185 activin binding 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0050786 RAGE receptor binding 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0050998 nitric-oxide synthase binding 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0070990 snRNP binding 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/809 11/18639 0.0909090909090909 2.09450500056186 0.386297468558277 0.655433659824182 GO:0008327 methyl-CpG binding 2/809 31/18639 0.0645161290322581 1.48642290362455 0.391972422912697 0.658433476714582 GO:0017147 Wnt-protein binding 2/809 31/18639 0.0645161290322581 1.48642290362455 0.391972422912697 0.658433476714582 GO:0030159 signaling receptor complex adaptor activity 3/809 52/18639 0.0576923076923077 1.32920509651041 0.394102895131973 0.658433476714582 GO:0004867 serine-type endopeptidase inhibitor activity 5/809 95/18639 0.0526315789473684 1.21260815822002 0.395794180329163 0.658433476714582 GO:0004866 endopeptidase inhibitor activity 8/809 161/18639 0.0496894409937888 1.14482260900276 0.399393242753429 0.658433476714582 GO:0003684 damaged DNA binding 4/809 74/18639 0.0540540540540541 1.24538135168543 0.40122017472852 0.658433476714582 GO:0035064 methylated histone binding 4/809 74/18639 0.0540540540540541 1.24538135168543 0.40122017472852 0.658433476714582 GO:0004864 protein phosphatase inhibitor activity 3/809 53/18639 0.0566037735849057 1.30412575506682 0.405912035050112 0.658433476714582 GO:0051018 protein kinase A binding 3/809 53/18639 0.0566037735849057 1.30412575506682 0.405912035050112 0.658433476714582 GO:0043425 bHLH transcription factor binding 2/809 32/18639 0.0625 1.43997218788628 0.407414314801031 0.658433476714582 GO:0019003 GDP binding 4/809 75/18639 0.0533333333333333 1.22877626699629 0.411094111617654 0.658433476714582 GO:0000340 RNA 7-methylguanosine cap binding 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0004000 adenosine deaminase activity 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0004859 phospholipase inhibitor activity 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0005025 transforming growth factor beta receptor activity, type I 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0005026 transforming growth factor beta receptor activity, type II 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0005165 neurotrophin receptor binding 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0008603 cAMP-dependent protein kinase regulator activity 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0015368 calcium:monoatomic cation antiporter activity 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0016273 arginine N-methyltransferase activity 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0016274 protein-arginine N-methyltransferase activity 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0016361 activin receptor activity, type I 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0016362 activin receptor activity, type II 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0017002 activin receptor activity 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0017166 vinculin binding 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0034452 dynactin binding 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0035251 UDP-glucosyltransferase activity 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0035497 cAMP response element binding 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0043047 single-stranded telomeric DNA binding 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0045295 gamma-catenin binding 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0070410 co-SMAD binding 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0070679 inositol 1,4,5 trisphosphate binding 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0097677 STAT family protein binding 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/809 12/18639 0.0833333333333333 1.91996291718171 0.412950106948676 0.658433476714582 GO:0140034 methylation-dependent protein binding 4/809 76/18639 0.0526315789473684 1.21260815822002 0.420933453736705 0.669911778372809 GO:0008017 microtubule binding 13/809 276/18639 0.0471014492753623 1.08519643145053 0.421548886569887 0.669911778372809 GO:0004518 nuclease activity 10/809 209/18639 0.0478468899521531 1.1023710529273 0.422201805164477 0.669911778372809 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 6/809 122/18639 0.0491803278688525 1.13309286915642 0.436970745270049 0.679175998813284 GO:0015020 glucuronosyltransferase activity 2/809 34/18639 0.0588235294117647 1.35526794154003 0.437706158215871 0.679175998813284 GO:0090482 vitamin transmembrane transporter activity 2/809 34/18639 0.0588235294117647 1.35526794154003 0.437706158215871 0.679175998813284 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/809 13/18639 0.0769230769230769 1.77227346201388 0.438446610061283 0.679175998813284 GO:0005035 death receptor activity 1/809 13/18639 0.0769230769230769 1.77227346201388 0.438446610061283 0.679175998813284 GO:0008253 5'-nucleotidase activity 1/809 13/18639 0.0769230769230769 1.77227346201388 0.438446610061283 0.679175998813284 GO:0009982 pseudouridine synthase activity 1/809 13/18639 0.0769230769230769 1.77227346201388 0.438446610061283 0.679175998813284 GO:0017154 semaphorin receptor activity 1/809 13/18639 0.0769230769230769 1.77227346201388 0.438446610061283 0.679175998813284 GO:0019855 calcium channel inhibitor activity 1/809 13/18639 0.0769230769230769 1.77227346201388 0.438446610061283 0.679175998813284 GO:0031994 insulin-like growth factor I binding 1/809 13/18639 0.0769230769230769 1.77227346201388 0.438446610061283 0.679175998813284 GO:0043560 insulin receptor substrate binding 1/809 13/18639 0.0769230769230769 1.77227346201388 0.438446610061283 0.679175998813284 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/809 13/18639 0.0769230769230769 1.77227346201388 0.438446610061283 0.679175998813284 GO:0046974 histone H3K9 methyltransferase activity 1/809 13/18639 0.0769230769230769 1.77227346201388 0.438446610061283 0.679175998813284 GO:0070123 transforming growth factor beta receptor activity, type III 1/809 13/18639 0.0769230769230769 1.77227346201388 0.438446610061283 0.679175998813284 GO:0071837 HMG box domain binding 1/809 13/18639 0.0769230769230769 1.77227346201388 0.438446610061283 0.679175998813284 GO:0019199 transmembrane receptor protein kinase activity 4/809 78/18639 0.0512820512820513 1.18151564134259 0.440487459509664 0.681259435797726 GO:0033293 monocarboxylic acid binding 4/809 79/18639 0.0506329113924051 1.16655974714838 0.450192193088459 0.695170594690223 GO:0030414 peptidase inhibitor activity 8/809 169/18639 0.0473372781065089 1.09062982277777 0.452392266115647 0.696587580617018 GO:0005343 organic acid:sodium symporter activity 2/809 35/18639 0.0571428571428571 1.31654600035317 0.452532892004519 0.696587580617018 GO:0008238 exopeptidase activity 5/809 102/18639 0.0490196078431373 1.12938995128336 0.456027904158684 0.700336152666652 GO:0008191 metalloendopeptidase inhibitor activity 1/809 14/18639 0.0714285714285714 1.64568250044146 0.462837069229135 0.700336152666652 GO:0008195 phosphatidate phosphatase activity 1/809 14/18639 0.0714285714285714 1.64568250044146 0.462837069229135 0.700336152666652 GO:0008494 translation activator activity 1/809 14/18639 0.0714285714285714 1.64568250044146 0.462837069229135 0.700336152666652 GO:0015386 potassium:proton antiporter activity 1/809 14/18639 0.0714285714285714 1.64568250044146 0.462837069229135 0.700336152666652 GO:0019763 immunoglobulin receptor activity 1/809 14/18639 0.0714285714285714 1.64568250044146 0.462837069229135 0.700336152666652 GO:0032454 histone H3K9 demethylase activity 1/809 14/18639 0.0714285714285714 1.64568250044146 0.462837069229135 0.700336152666652 GO:0070742 C2H2 zinc finger domain binding 1/809 14/18639 0.0714285714285714 1.64568250044146 0.462837069229135 0.700336152666652 GO:0071933 Arp2/3 complex binding 1/809 14/18639 0.0714285714285714 1.64568250044146 0.462837069229135 0.700336152666652 GO:0098821 BMP receptor activity 1/809 14/18639 0.0714285714285714 1.64568250044146 0.462837069229135 0.700336152666652 GO:0098847 sequence-specific single stranded DNA binding 1/809 14/18639 0.0714285714285714 1.64568250044146 0.462837069229135 0.700336152666652 GO:0055106 ubiquitin-protein transferase regulator activity 2/809 36/18639 0.0555555555555556 1.27997527812114 0.467133639382185 0.705746655794999 GO:0030280 structural constituent of skin epidermis 2/809 37/18639 0.0540540540540541 1.24538135168543 0.481500072464386 0.71580485004387 GO:0004953 icosanoid receptor activity 1/809 15/18639 0.0666666666666667 1.53597033374536 0.486169408074431 0.71580485004387 GO:0005041 low-density lipoprotein particle receptor activity 1/809 15/18639 0.0666666666666667 1.53597033374536 0.486169408074431 0.71580485004387 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/809 15/18639 0.0666666666666667 1.53597033374536 0.486169408074431 0.71580485004387 GO:0008252 nucleotidase activity 1/809 15/18639 0.0666666666666667 1.53597033374536 0.486169408074431 0.71580485004387 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/809 15/18639 0.0666666666666667 1.53597033374536 0.486169408074431 0.71580485004387 GO:0016846 carbon-sulfur lyase activity 1/809 15/18639 0.0666666666666667 1.53597033374536 0.486169408074431 0.71580485004387 GO:0030553 cGMP binding 1/809 15/18639 0.0666666666666667 1.53597033374536 0.486169408074431 0.71580485004387 GO:0033130 acetylcholine receptor binding 1/809 15/18639 0.0666666666666667 1.53597033374536 0.486169408074431 0.71580485004387 GO:0042809 nuclear vitamin D receptor binding 1/809 15/18639 0.0666666666666667 1.53597033374536 0.486169408074431 0.71580485004387 GO:0047372 monoacylglycerol lipase activity 1/809 15/18639 0.0666666666666667 1.53597033374536 0.486169408074431 0.71580485004387 GO:0048531 beta-1,3-galactosyltransferase activity 1/809 15/18639 0.0666666666666667 1.53597033374536 0.486169408074431 0.71580485004387 GO:0050700 CARD domain binding 1/809 15/18639 0.0666666666666667 1.53597033374536 0.486169408074431 0.71580485004387 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/809 15/18639 0.0666666666666667 1.53597033374536 0.486169408074431 0.71580485004387 GO:0141050 histone H3K deacetylase activity 1/809 15/18639 0.0666666666666667 1.53597033374536 0.486169408074431 0.71580485004387 GO:0141051 histone H4K deacetylase activity 1/809 15/18639 0.0666666666666667 1.53597033374536 0.486169408074431 0.71580485004387 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/809 60/18639 0.05 1.15197775030902 0.4862208634108 0.71580485004387 GO:0005501 retinoid binding 2/809 38/18639 0.0526315789473684 1.21260815822002 0.495625009803587 0.726372581733101 GO:0019840 isoprenoid binding 2/809 38/18639 0.0526315789473684 1.21260815822002 0.495625009803587 0.726372581733101 GO:0042162 telomeric DNA binding 2/809 38/18639 0.0526315789473684 1.21260815822002 0.495625009803587 0.726372581733101 GO:0043021 ribonucleoprotein complex binding 8/809 177/18639 0.0451977401129944 1.04133581948838 0.504543891328429 0.728859732364434 GO:0003688 DNA replication origin binding 1/809 16/18639 0.0625 1.43997218788628 0.508489476205218 0.728859732364434 GO:0004708 MAP kinase kinase activity 1/809 16/18639 0.0625 1.43997218788628 0.508489476205218 0.728859732364434 GO:0005024 transforming growth factor beta receptor activity 1/809 16/18639 0.0625 1.43997218788628 0.508489476205218 0.728859732364434 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/809 16/18639 0.0625 1.43997218788628 0.508489476205218 0.728859732364434 GO:0005521 lamin binding 1/809 16/18639 0.0625 1.43997218788628 0.508489476205218 0.728859732364434 GO:0008142 oxysterol binding 1/809 16/18639 0.0625 1.43997218788628 0.508489476205218 0.728859732364434 GO:0008296 3'-5'-DNA exonuclease activity 1/809 16/18639 0.0625 1.43997218788628 0.508489476205218 0.728859732364434 GO:0015385 sodium:proton antiporter activity 1/809 16/18639 0.0625 1.43997218788628 0.508489476205218 0.728859732364434 GO:0022858 alanine transmembrane transporter activity 1/809 16/18639 0.0625 1.43997218788628 0.508489476205218 0.728859732364434 GO:0030275 LRR domain binding 1/809 16/18639 0.0625 1.43997218788628 0.508489476205218 0.728859732364434 GO:0055102 lipase inhibitor activity 1/809 16/18639 0.0625 1.43997218788628 0.508489476205218 0.728859732364434 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/809 16/18639 0.0625 1.43997218788628 0.508489476205218 0.728859732364434 GO:0070411 I-SMAD binding 1/809 16/18639 0.0625 1.43997218788628 0.508489476205218 0.728859732364434 GO:0097027 ubiquitin-protein transferase activator activity 1/809 16/18639 0.0625 1.43997218788628 0.508489476205218 0.728859732364434 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/809 39/18639 0.0512820512820513 1.18151564134259 0.509502332775938 0.729243835946847 GO:0140098 catalytic activity, acting on RNA 17/809 387/18639 0.0439276485788114 1.01207347572369 0.515138036414932 0.73623377759156 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/809 86/18639 0.0465116279069767 1.07160720958979 0.516365490358956 0.736912266853379 GO:0051087 protein-folding chaperone binding 6/809 134/18639 0.0447761194029851 1.03162186594838 0.527813574601891 0.739963587661588 GO:0004536 DNA nuclease activity 3/809 64/18639 0.046875 1.07997914091471 0.529698651080577 0.739963587661588 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/809 17/18639 0.0588235294117647 1.35526794154003 0.52984113886698 0.739963587661588 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/809 17/18639 0.0588235294117647 1.35526794154003 0.52984113886698 0.739963587661588 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/809 17/18639 0.0588235294117647 1.35526794154003 0.52984113886698 0.739963587661588 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/809 17/18639 0.0588235294117647 1.35526794154003 0.52984113886698 0.739963587661588 GO:0016018 cyclosporin A binding 1/809 17/18639 0.0588235294117647 1.35526794154003 0.52984113886698 0.739963587661588 GO:0019198 transmembrane receptor protein phosphatase activity 1/809 17/18639 0.0588235294117647 1.35526794154003 0.52984113886698 0.739963587661588 GO:0030548 acetylcholine receptor regulator activity 1/809 17/18639 0.0588235294117647 1.35526794154003 0.52984113886698 0.739963587661588 GO:0036041 long-chain fatty acid binding 1/809 17/18639 0.0588235294117647 1.35526794154003 0.52984113886698 0.739963587661588 GO:0038191 neuropilin binding 1/809 17/18639 0.0588235294117647 1.35526794154003 0.52984113886698 0.739963587661588 GO:0045125 bioactive lipid receptor activity 1/809 17/18639 0.0588235294117647 1.35526794154003 0.52984113886698 0.739963587661588 GO:0045236 CXCR chemokine receptor binding 1/809 17/18639 0.0588235294117647 1.35526794154003 0.52984113886698 0.739963587661588 GO:0051787 misfolded protein binding 1/809 17/18639 0.0588235294117647 1.35526794154003 0.52984113886698 0.739963587661588 GO:0070492 oligosaccharide binding 1/809 17/18639 0.0588235294117647 1.35526794154003 0.52984113886698 0.739963587661588 GO:1902936 phosphatidylinositol bisphosphate binding 5/809 111/18639 0.045045045045045 1.03781779307119 0.530704139418835 0.740113037736523 GO:1901681 sulfur compound binding 12/809 275/18639 0.0436363636363636 1.00536240026969 0.53423792652375 0.743569041245598 GO:0001530 lipopolysaccharide binding 2/809 41/18639 0.0487804878048781 1.1238807320088 0.536494508867666 0.743569041245598 GO:0042169 SH2 domain binding 2/809 41/18639 0.0487804878048781 1.1238807320088 0.536494508867666 0.743569041245598 GO:0140828 metal cation:monoatomic cation antiporter activity 2/809 41/18639 0.0487804878048781 1.1238807320088 0.536494508867666 0.743569041245598 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 10/809 229/18639 0.0436681222707424 1.00609410507338 0.537813014562466 0.743569041245598 GO:0099106 ion channel regulator activity 7/809 160/18639 0.04375 1.0079805315204 0.545750203686923 0.743569041245598 GO:0008237 metallopeptidase activity 8/809 184/18639 0.0434782608695652 1.00171978287741 0.548857633311069 0.743569041245598 GO:0004520 DNA endonuclease activity 2/809 42/18639 0.0476190476190476 1.09712166696097 0.549601755829828 0.743569041245598 GO:0019894 kinesin binding 2/809 42/18639 0.0476190476190476 1.09712166696097 0.549601755829828 0.743569041245598 GO:0042056 chemoattractant activity 2/809 42/18639 0.0476190476190476 1.09712166696097 0.549601755829828 0.743569041245598 GO:0000900 mRNA regulatory element binding translation repressor activity 1/809 18/18639 0.0555555555555556 1.27997527812114 0.550266362723526 0.743569041245598 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/809 18/18639 0.0555555555555556 1.27997527812114 0.550266362723526 0.743569041245598 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/809 18/18639 0.0555555555555556 1.27997527812114 0.550266362723526 0.743569041245598 GO:0008409 5'-3' exonuclease activity 1/809 18/18639 0.0555555555555556 1.27997527812114 0.550266362723526 0.743569041245598 GO:0017128 phospholipid scramblase activity 1/809 18/18639 0.0555555555555556 1.27997527812114 0.550266362723526 0.743569041245598 GO:0030228 lipoprotein particle receptor activity 1/809 18/18639 0.0555555555555556 1.27997527812114 0.550266362723526 0.743569041245598 GO:0032393 MHC class I receptor activity 1/809 18/18639 0.0555555555555556 1.27997527812114 0.550266362723526 0.743569041245598 GO:0034185 apolipoprotein binding 1/809 18/18639 0.0555555555555556 1.27997527812114 0.550266362723526 0.743569041245598 GO:0035615 clathrin adaptor activity 1/809 18/18639 0.0555555555555556 1.27997527812114 0.550266362723526 0.743569041245598 GO:0070064 proline-rich region binding 1/809 18/18639 0.0555555555555556 1.27997527812114 0.550266362723526 0.743569041245598 GO:0099602 neurotransmitter receptor regulator activity 1/809 18/18639 0.0555555555555556 1.27997527812114 0.550266362723526 0.743569041245598 GO:1990381 ubiquitin-specific protease binding 1/809 18/18639 0.0555555555555556 1.27997527812114 0.550266362723526 0.743569041245598 GO:0008235 metalloexopeptidase activity 3/809 66/18639 0.0454545454545455 1.04725250028093 0.550651230748783 0.743569041245598 GO:0008200 ion channel inhibitor activity 2/809 43/18639 0.0465116279069767 1.07160720958979 0.562446041998707 0.757933949290101 GO:0005520 insulin-like growth factor binding 1/809 19/18639 0.0526315789473684 1.21260815822002 0.569805297934131 0.757933949290101 GO:0015245 fatty acid transmembrane transporter activity 1/809 19/18639 0.0526315789473684 1.21260815822002 0.569805297934131 0.757933949290101 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/809 19/18639 0.0526315789473684 1.21260815822002 0.569805297934131 0.757933949290101 GO:0034987 immunoglobulin receptor binding 1/809 19/18639 0.0526315789473684 1.21260815822002 0.569805297934131 0.757933949290101 GO:0042577 lipid phosphatase activity 1/809 19/18639 0.0526315789473684 1.21260815822002 0.569805297934131 0.757933949290101 GO:0042834 peptidoglycan binding 1/809 19/18639 0.0526315789473684 1.21260815822002 0.569805297934131 0.757933949290101 GO:0046527 glucosyltransferase activity 1/809 19/18639 0.0526315789473684 1.21260815822002 0.569805297934131 0.757933949290101 GO:0046624 sphingolipid transporter activity 1/809 19/18639 0.0526315789473684 1.21260815822002 0.569805297934131 0.757933949290101 GO:0050145 nucleoside monophosphate kinase activity 1/809 19/18639 0.0526315789473684 1.21260815822002 0.569805297934131 0.757933949290101 GO:0097001 ceramide binding 1/809 19/18639 0.0526315789473684 1.21260815822002 0.569805297934131 0.757933949290101 GO:0016248 channel inhibitor activity 2/809 44/18639 0.0454545454545455 1.04725250028093 0.575025477010719 0.761772587271304 GO:0019205 nucleobase-containing compound kinase activity 2/809 44/18639 0.0454545454545455 1.04725250028093 0.575025477010719 0.761772587271304 GO:0030547 signaling receptor inhibitor activity 2/809 44/18639 0.0454545454545455 1.04725250028093 0.575025477010719 0.761772587271304 GO:0141110 transporter inhibitor activity 2/809 45/18639 0.0444444444444444 1.02398022249691 0.587338829011721 0.773339507645903 GO:0000339 RNA cap binding 1/809 20/18639 0.05 1.15197775030902 0.588496356686617 0.773339507645903 GO:0001614 purinergic nucleotide receptor activity 1/809 20/18639 0.05 1.15197775030902 0.588496356686617 0.773339507645903 GO:0001972 retinoic acid binding 1/809 20/18639 0.05 1.15197775030902 0.588496356686617 0.773339507645903 GO:0016502 nucleotide receptor activity 1/809 20/18639 0.05 1.15197775030902 0.588496356686617 0.773339507645903 GO:0016505 peptidase activator activity involved in apoptotic process 1/809 20/18639 0.05 1.15197775030902 0.588496356686617 0.773339507645903 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 7/809 167/18639 0.0419161676646707 0.965729850558463 0.591383630204849 0.776091922212529 GO:0016247 channel regulator activity 7/809 168/18639 0.0416666666666667 0.959981458590853 0.597713522794791 0.783348780208969 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/809 21/18639 0.0476190476190476 1.09712166696097 0.606376288339258 0.789418066867199 GO:0005123 death receptor binding 1/809 21/18639 0.0476190476190476 1.09712166696097 0.606376288339258 0.789418066867199 GO:0009975 cyclase activity 1/809 21/18639 0.0476190476190476 1.09712166696097 0.606376288339258 0.789418066867199 GO:0019200 carbohydrate kinase activity 1/809 21/18639 0.0476190476190476 1.09712166696097 0.606376288339258 0.789418066867199 GO:0035613 RNA stem-loop binding 1/809 21/18639 0.0476190476190476 1.09712166696097 0.606376288339258 0.789418066867199 GO:0141108 transporter regulator activity 7/809 170/18639 0.0411764705882353 0.948687559078019 0.61022059489062 0.793367811949425 GO:0008201 heparin binding 7/809 172/18639 0.0406976744186047 0.937656308391066 0.622517777301705 0.802085632115737 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/809 48/18639 0.0416666666666667 0.959981458590853 0.62267884670536 0.802085632115737 GO:0032266 phosphatidylinositol-3-phosphate binding 2/809 48/18639 0.0416666666666667 0.959981458590853 0.62267884670536 0.802085632115737 GO:0004407 histone deacetylase activity 1/809 22/18639 0.0454545454545455 1.04725250028093 0.623480251317749 0.802085632115737 GO:0008093 cytoskeletal anchor activity 1/809 22/18639 0.0454545454545455 1.04725250028093 0.623480251317749 0.802085632115737 GO:0008970 phospholipase A1 activity 1/809 22/18639 0.0454545454545455 1.04725250028093 0.623480251317749 0.802085632115737 GO:0033558 protein lysine deacetylase activity 1/809 22/18639 0.0454545454545455 1.04725250028093 0.623480251317749 0.802085632115737 GO:0140517 protein-RNA adaptor activity 1/809 22/18639 0.0454545454545455 1.04725250028093 0.623480251317749 0.802085632115737 GO:0005004 GPI-linked ephrin receptor activity 2/809 49/18639 0.0408163265306122 0.940390000252264 0.633926916705935 0.803904729864133 GO:0005008 hepatocyte growth factor receptor activity 2/809 49/18639 0.0408163265306122 0.940390000252264 0.633926916705935 0.803904729864133 GO:0005009 insulin receptor activity 2/809 49/18639 0.0408163265306122 0.940390000252264 0.633926916705935 0.803904729864133 GO:0005011 macrophage colony-stimulating factor receptor activity 2/809 49/18639 0.0408163265306122 0.940390000252264 0.633926916705935 0.803904729864133 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/809 49/18639 0.0408163265306122 0.940390000252264 0.633926916705935 0.803904729864133 GO:0005020 stem cell factor receptor activity 2/809 49/18639 0.0408163265306122 0.940390000252264 0.633926916705935 0.803904729864133 GO:0008288 boss receptor activity 2/809 49/18639 0.0408163265306122 0.940390000252264 0.633926916705935 0.803904729864133 GO:0036332 placental growth factor receptor activity 2/809 49/18639 0.0408163265306122 0.940390000252264 0.633926916705935 0.803904729864133 GO:0038062 protein tyrosine kinase collagen receptor activity 2/809 49/18639 0.0408163265306122 0.940390000252264 0.633926916705935 0.803904729864133 GO:0060175 brain-derived neurotrophic factor receptor activity 2/809 49/18639 0.0408163265306122 0.940390000252264 0.633926916705935 0.803904729864133 GO:0060590 ATPase regulator activity 2/809 49/18639 0.0408163265306122 0.940390000252264 0.633926916705935 0.803904729864133 GO:0003887 DNA-directed DNA polymerase activity 1/809 23/18639 0.0434782608695652 1.00171978287741 0.639841881907206 0.80618430165657 GO:0004602 glutathione peroxidase activity 1/809 23/18639 0.0434782608695652 1.00171978287741 0.639841881907206 0.80618430165657 GO:0005283 amino acid:sodium symporter activity 1/809 23/18639 0.0434782608695652 1.00171978287741 0.639841881907206 0.80618430165657 GO:0016493 C-C chemokine receptor activity 1/809 23/18639 0.0434782608695652 1.00171978287741 0.639841881907206 0.80618430165657 GO:0017134 fibroblast growth factor binding 1/809 23/18639 0.0434782608695652 1.00171978287741 0.639841881907206 0.80618430165657 GO:0005006 epidermal growth factor receptor activity 2/809 50/18639 0.04 0.921582200247219 0.644910865303065 0.808393098927094 GO:0005007 fibroblast growth factor receptor activity 2/809 50/18639 0.04 0.921582200247219 0.644910865303065 0.808393098927094 GO:0005017 platelet-derived growth factor receptor activity 2/809 50/18639 0.04 0.921582200247219 0.644910865303065 0.808393098927094 GO:0005019 platelet-derived growth factor beta-receptor activity 2/809 50/18639 0.04 0.921582200247219 0.644910865303065 0.808393098927094 GO:0098631 cell adhesion mediator activity 3/809 76/18639 0.0394736842105263 0.909456118665019 0.646625265807269 0.808393098927094 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/809 24/18639 0.0416666666666667 0.959981458590853 0.655493360073143 0.808393098927094 GO:0004806 triacylglycerol lipase activity 1/809 24/18639 0.0416666666666667 0.959981458590853 0.655493360073143 0.808393098927094 GO:0005540 hyaluronic acid binding 1/809 24/18639 0.0416666666666667 0.959981458590853 0.655493360073143 0.808393098927094 GO:0015295 solute:proton symporter activity 1/809 24/18639 0.0416666666666667 0.959981458590853 0.655493360073143 0.808393098927094 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/809 24/18639 0.0416666666666667 0.959981458590853 0.655493360073143 0.808393098927094 GO:0030215 semaphorin receptor binding 1/809 24/18639 0.0416666666666667 0.959981458590853 0.655493360073143 0.808393098927094 GO:0048027 mRNA 5'-UTR binding 1/809 24/18639 0.0416666666666667 0.959981458590853 0.655493360073143 0.808393098927094 GO:0050431 transforming growth factor beta binding 1/809 24/18639 0.0416666666666667 0.959981458590853 0.655493360073143 0.808393098927094 GO:0070840 dynein complex binding 1/809 24/18639 0.0416666666666667 0.959981458590853 0.655493360073143 0.808393098927094 GO:0003743 translation initiation factor activity 2/809 51/18639 0.0392156862745098 0.903511961026685 0.65563240096845 0.808393098927094 GO:0005021 vascular endothelial growth factor receptor activity 2/809 51/18639 0.0392156862745098 0.903511961026685 0.65563240096845 0.808393098927094 GO:0005030 neurotrophin receptor activity 2/809 51/18639 0.0392156862745098 0.903511961026685 0.65563240096845 0.808393098927094 GO:0003774 cytoskeletal motor activity 6/809 153/18639 0.0392156862745098 0.903511961026685 0.657155623216042 0.809252019029566 GO:0019001 guanyl nucleotide binding 16/809 400/18639 0.04 0.921582200247219 0.667354209941273 0.817363573975226 GO:0032561 guanyl ribonucleotide binding 16/809 400/18639 0.04 0.921582200247219 0.667354209941273 0.817363573975226 GO:0000030 mannosyltransferase activity 1/809 25/18639 0.04 0.921582200247219 0.670465472439558 0.817363573975226 GO:0015662 P-type ion transporter activity 1/809 25/18639 0.04 0.921582200247219 0.670465472439558 0.817363573975226 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/809 25/18639 0.04 0.921582200247219 0.670465472439558 0.817363573975226 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/809 25/18639 0.04 0.921582200247219 0.670465472439558 0.817363573975226 GO:0140358 P-type transmembrane transporter activity 1/809 25/18639 0.04 0.921582200247219 0.670465472439558 0.817363573975226 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 5/809 130/18639 0.0384615384615385 0.886136731006941 0.670562065460195 0.817363573975226 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 7/809 181/18639 0.0386740331491713 0.891032514051178 0.675090142221335 0.817363573975226 GO:0005525 GTP binding 15/809 378/18639 0.0396825396825397 0.914268055800812 0.676181913488014 0.817363573975226 GO:0005003 ephrin receptor activity 2/809 53/18639 0.0377358490566038 0.869417170044546 0.676296779090215 0.817363573975226 GO:0005005 transmembrane-ephrin receptor activity 2/809 53/18639 0.0377358490566038 0.869417170044546 0.676296779090215 0.817363573975226 GO:0038064 collagen receptor activity 2/809 53/18639 0.0377358490566038 0.869417170044546 0.676296779090215 0.817363573975226 GO:0004529 DNA exonuclease activity 1/809 26/18639 0.0384615384615385 0.886136731006941 0.684787672546811 0.817363573975226 GO:0005112 Notch binding 1/809 26/18639 0.0384615384615385 0.886136731006941 0.684787672546811 0.817363573975226 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/809 26/18639 0.0384615384615385 0.886136731006941 0.684787672546811 0.817363573975226 GO:0008157 protein phosphatase 1 binding 1/809 26/18639 0.0384615384615385 0.886136731006941 0.684787672546811 0.817363573975226 GO:0008198 ferrous iron binding 1/809 26/18639 0.0384615384615385 0.886136731006941 0.684787672546811 0.817363573975226 GO:0019865 immunoglobulin binding 1/809 26/18639 0.0384615384615385 0.886136731006941 0.684787672546811 0.817363573975226 GO:0030507 spectrin binding 1/809 26/18639 0.0384615384615385 0.886136731006941 0.684787672546811 0.817363573975226 GO:0034237 protein kinase A regulatory subunit binding 1/809 26/18639 0.0384615384615385 0.886136731006941 0.684787672546811 0.817363573975226 GO:0050681 nuclear androgen receptor binding 1/809 26/18639 0.0384615384615385 0.886136731006941 0.684787672546811 0.817363573975226 GO:0051139 metal cation:proton antiporter activity 1/809 26/18639 0.0384615384615385 0.886136731006941 0.684787672546811 0.817363573975226 GO:0070412 R-SMAD binding 1/809 26/18639 0.0384615384615385 0.886136731006941 0.684787672546811 0.817363573975226 GO:0097602 cullin family protein binding 1/809 26/18639 0.0384615384615385 0.886136731006941 0.684787672546811 0.817363573975226 GO:0051287 NAD binding 2/809 54/18639 0.037037037037037 0.853316852080758 0.686244652105241 0.817363573975226 GO:0004175 endopeptidase activity 16/809 405/18639 0.0395061728395062 0.910204642219475 0.686284839435787 0.817363573975226 GO:0030971 receptor tyrosine kinase binding 3/809 81/18639 0.037037037037037 0.853316852080758 0.688819309528311 0.819385302585925 GO:0004364 glutathione transferase activity 1/809 27/18639 0.037037037037037 0.853316852080758 0.698488138506604 0.824873205787655 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/809 27/18639 0.037037037037037 0.853316852080758 0.698488138506604 0.824873205787655 GO:0005044 scavenger receptor activity 1/809 27/18639 0.037037037037037 0.853316852080758 0.698488138506604 0.824873205787655 GO:0005104 fibroblast growth factor receptor binding 1/809 27/18639 0.037037037037037 0.853316852080758 0.698488138506604 0.824873205787655 GO:0005385 zinc ion transmembrane transporter activity 1/809 27/18639 0.037037037037037 0.853316852080758 0.698488138506604 0.824873205787655 GO:0008320 protein transmembrane transporter activity 1/809 27/18639 0.037037037037037 0.853316852080758 0.698488138506604 0.824873205787655 GO:0008135 translation factor activity, RNA binding 3/809 83/18639 0.036144578313253 0.83275500022339 0.704602277954382 0.830015853838734 GO:0030170 pyridoxal phosphate binding 2/809 56/18639 0.0357142857142857 0.822841250220731 0.705386302751611 0.830015853838734 GO:0170055 lipid transmembrane transporter activity 2/809 56/18639 0.0357142857142857 0.822841250220731 0.705386302751611 0.830015853838734 GO:0004222 metalloendopeptidase activity 4/809 110/18639 0.0363636363636364 0.837802000224744 0.70869231423671 0.831112817588616 GO:0008083 growth factor activity 6/809 162/18639 0.037037037037037 0.853316852080758 0.710107324920172 0.831112817588616 GO:0016866 intramolecular transferase activity 1/809 28/18639 0.0357142857142857 0.822841250220731 0.711593828166402 0.831112817588616 GO:0051959 dynein light intermediate chain binding 1/809 28/18639 0.0357142857142857 0.822841250220731 0.711593828166402 0.831112817588616 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/809 28/18639 0.0357142857142857 0.822841250220731 0.711593828166402 0.831112817588616 GO:0051117 ATPase binding 3/809 84/18639 0.0357142857142857 0.822841250220731 0.712261137851735 0.831112817588616 GO:0180051 translation factor activity 3/809 84/18639 0.0357142857142857 0.822841250220731 0.712261137851735 0.831112817588616 GO:0070279 vitamin B6 binding 2/809 57/18639 0.0350877192982456 0.80840543881335 0.714586565215359 0.832833627792662 GO:0005200 structural constituent of cytoskeleton 4/809 112/18639 0.0357142857142857 0.822841250220731 0.721887546696415 0.837971383830993 GO:0004181 metallocarboxypeptidase activity 1/809 29/18639 0.0344827586206897 0.794467414006223 0.724130531890725 0.837971383830993 GO:0005416 amino acid:monoatomic cation symporter activity 1/809 29/18639 0.0344827586206897 0.794467414006223 0.724130531890725 0.837971383830993 GO:0016417 S-acyltransferase activity 1/809 29/18639 0.0344827586206897 0.794467414006223 0.724130531890725 0.837971383830993 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/809 29/18639 0.0344827586206897 0.794467414006223 0.724130531890725 0.837971383830993 GO:0051861 glycolipid binding 1/809 29/18639 0.0344827586206897 0.794467414006223 0.724130531890725 0.837971383830993 GO:0016209 antioxidant activity 3/809 86/18639 0.0348837209302326 0.803705407192342 0.727117821533398 0.840434884629511 GO:0015459 potassium channel regulator activity 2/809 59/18639 0.0338983050847458 0.781001864616287 0.732263559300932 0.844388721502489 GO:0036002 pre-mRNA binding 2/809 59/18639 0.0338983050847458 0.781001864616287 0.732263559300932 0.844388721502489 GO:0015215 nucleotide transmembrane transporter activity 1/809 30/18639 0.0333333333333333 0.767985166872682 0.73612292306216 0.847840401973947 GO:0008236 serine-type peptidase activity 7/809 194/18639 0.0360824742268041 0.831324149707543 0.74246017214822 0.854134557618223 GO:0047499 calcium-independent phospholipase A2 activity 1/809 31/18639 0.032258064516129 0.743211451812273 0.747594606400476 0.858024759280265 GO:0070273 phosphatidylinositol-4-phosphate binding 1/809 31/18639 0.032258064516129 0.743211451812273 0.747594606400476 0.858024759280265 GO:0015179 L-amino acid transmembrane transporter activity 2/809 62/18639 0.032258064516129 0.743211451812273 0.7570273863727 0.864538105641365 GO:0022884 macromolecule transmembrane transporter activity 1/809 32/18639 0.03125 0.71998609394314 0.758568164194006 0.864538105641365 GO:0030515 snoRNA binding 1/809 32/18639 0.03125 0.71998609394314 0.758568164194006 0.864538105641365 GO:0047498 calcium-dependent phospholipase A2 activity 1/809 32/18639 0.03125 0.71998609394314 0.758568164194006 0.864538105641365 GO:0071813 lipoprotein particle binding 1/809 32/18639 0.03125 0.71998609394314 0.758568164194006 0.864538105641365 GO:0071814 protein-lipid complex binding 1/809 32/18639 0.03125 0.71998609394314 0.758568164194006 0.864538105641365 GO:0017171 serine hydrolase activity 7/809 198/18639 0.0353535353535354 0.814529722440724 0.761080750631563 0.866003490135825 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/809 91/18639 0.032967032967033 0.759545769434521 0.761623089894735 0.866003490135825 GO:0015293 symporter activity 5/809 146/18639 0.0342465753424658 0.789025856376043 0.764754566603279 0.868555360446184 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/809 33/18639 0.0303030303030303 0.69816833352062 0.769065200533397 0.870421770314677 GO:0019239 deaminase activity 1/809 33/18639 0.0303030303030303 0.69816833352062 0.769065200533397 0.870421770314677 GO:0140416 transcription regulator inhibitor activity 1/809 33/18639 0.0303030303030303 0.69816833352062 0.769065200533397 0.870421770314677 GO:0016829 lyase activity 7/809 200/18639 0.035 0.806384425216316 0.770018468279213 0.870494319220958 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/809 34/18639 0.0294117647058824 0.677633970770014 0.779106383633928 0.876718562732892 GO:0016831 carboxy-lyase activity 1/809 34/18639 0.0294117647058824 0.677633970770014 0.779106383633928 0.876718562732892 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/809 34/18639 0.0294117647058824 0.677633970770014 0.779106383633928 0.876718562732892 GO:0051427 hormone receptor binding 1/809 34/18639 0.0294117647058824 0.677633970770014 0.779106383633928 0.876718562732892 GO:0008528 G protein-coupled peptide receptor activity 4/809 122/18639 0.0327868852459016 0.755395246104278 0.781224752477203 0.878093034070243 GO:0008168 methyltransferase activity 7/809 204/18639 0.0343137254901961 0.790572965898349 0.787154652257787 0.88346515459497 GO:0004623 phospholipase A2 activity 1/809 35/18639 0.0285714285714286 0.658273000176585 0.788711486328911 0.88346515459497 GO:0034061 DNA polymerase activity 1/809 35/18639 0.0285714285714286 0.658273000176585 0.788711486328911 0.88346515459497 GO:0016500 protein-hormone receptor activity 2/809 67/18639 0.0298507462686567 0.687747910632253 0.79390156730842 0.886233285335044 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/809 67/18639 0.0298507462686567 0.687747910632253 0.79390156730842 0.886233285335044 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/809 36/18639 0.0277777777777778 0.639987639060569 0.797899424813103 0.886233285335044 GO:0005484 SNAP receptor activity 1/809 36/18639 0.0277777777777778 0.639987639060569 0.797899424813103 0.886233285335044 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/809 36/18639 0.0277777777777778 0.639987639060569 0.797899424813103 0.886233285335044 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/809 36/18639 0.0277777777777778 0.639987639060569 0.797899424813103 0.886233285335044 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/809 36/18639 0.0277777777777778 0.639987639060569 0.797899424813103 0.886233285335044 GO:0016853 isomerase activity 6/809 180/18639 0.0333333333333333 0.767985166872682 0.798424675858538 0.886233285335044 GO:0019213 deacetylase activity 1/809 37/18639 0.027027027027027 0.622690675842715 0.806688295711679 0.89237044237484 GO:0022829 wide pore channel activity 1/809 37/18639 0.027027027027027 0.622690675842715 0.806688295711679 0.89237044237484 GO:0042805 actinin binding 1/809 37/18639 0.027027027027027 0.622690675842715 0.806688295711679 0.89237044237484 GO:0001653 peptide receptor activity 4/809 128/18639 0.03125 0.71998609394314 0.811721325584446 0.896924579850082 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/809 70/18639 0.0285714285714286 0.658273000176585 0.813574737187053 0.897959039127536 GO:0005109 frizzled binding 1/809 38/18639 0.0263157894736842 0.606304079110012 0.815095411547032 0.898624333225839 GO:0016298 lipase activity 4/809 130/18639 0.0307692307692308 0.708909384805553 0.821082068160098 0.903190274976108 GO:0016798 hydrolase activity, acting on glycosyl bonds 4/809 130/18639 0.0307692307692308 0.708909384805553 0.821082068160098 0.903190274976108 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/809 39/18639 0.0256410256410256 0.590757820671294 0.823137334672588 0.903420908794241 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/809 39/18639 0.0256410256410256 0.590757820671294 0.823137334672588 0.903420908794241 GO:0016741 transferase activity, transferring one-carbon groups 7/809 215/18639 0.0325581395348837 0.750125046712853 0.829320058941311 0.906780915981326 GO:0005179 hormone activity 4/809 132/18639 0.0303030303030303 0.69816833352062 0.830055693113632 0.906780915981326 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/809 40/18639 0.025 0.575988875154512 0.830829909739785 0.906780915981326 GO:0061791 GTPase motor activity 1/809 40/18639 0.025 0.575988875154512 0.830829909739785 0.906780915981326 GO:1990606 membrane scission GTPase motor activity 1/809 40/18639 0.025 0.575988875154512 0.830829909739785 0.906780915981326 GO:0043177 organic acid binding 6/809 189/18639 0.0317460317460317 0.73141444464065 0.834038836059833 0.909269510581934 GO:0031491 nucleosome binding 2/809 74/18639 0.027027027027027 0.622690675842715 0.837188904639669 0.909740954070504 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/809 41/18639 0.024390243902439 0.561940366004402 0.838188294761588 0.909740954070504 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/809 41/18639 0.024390243902439 0.561940366004402 0.838188294761588 0.909740954070504 GO:0140318 protein transporter activity 1/809 41/18639 0.024390243902439 0.561940366004402 0.838188294761588 0.909740954070504 GO:0044183 protein folding chaperone 2/809 75/18639 0.0266666666666667 0.614388133498146 0.842653905356133 0.912735281111098 GO:0015297 antiporter activity 4/809 135/18639 0.0296296296296296 0.682653481664606 0.842811740678685 0.912735281111098 GO:0016859 cis-trans isomerase activity 1/809 42/18639 0.0238095238095238 0.548560833480487 0.845226990833094 0.913330269343929 GO:0031492 nucleosomal DNA binding 1/809 42/18639 0.0238095238095238 0.548560833480487 0.845226990833094 0.913330269343929 GO:0005245 voltage-gated calcium channel activity 1/809 43/18639 0.0232558139534884 0.535803604794895 0.851959870567247 0.918577878067549 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/809 43/18639 0.0232558139534884 0.535803604794895 0.851959870567247 0.918577878067549 GO:0004620 phospholipase activity 3/809 109/18639 0.0275229357798165 0.634116192830655 0.857482880047692 0.92264402834122 GO:0016790 thiolester hydrolase activity 1/809 44/18639 0.0227272727272727 0.523626250140465 0.858400205301119 0.92264402834122 GO:0140101 catalytic activity, acting on a tRNA 4/809 139/18639 0.0287769784172662 0.663008777156273 0.858558436995762 0.92264402834122 GO:0015370 solute:sodium symporter activity 2/809 79/18639 0.0253164556962025 0.583279873574189 0.862886106216952 0.926277958318417 GO:0048306 calcium-dependent protein binding 2/809 80/18639 0.025 0.575988875154512 0.867557700687322 0.930272715194839 GO:0004180 carboxypeptidase activity 1/809 46/18639 0.0217391304347826 0.500859891438706 0.87045347379121 0.931337651192999 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/809 46/18639 0.0217391304347826 0.500859891438706 0.87045347379121 0.931337651192999 GO:0015101 organic cation transmembrane transporter activity 2/809 81/18639 0.0246913580246914 0.568877901387172 0.872082723248309 0.932062211855998 GO:0140359 ABC-type transporter activity 1/809 47/18639 0.0212765957446809 0.49020329800384 0.876090172532828 0.935324186379104 GO:0004252 serine-type endopeptidase activity 5/809 176/18639 0.0284090909090909 0.654532812675581 0.884359428566665 0.942246539136922 GO:0015294 solute:monoatomic cation symporter activity 3/809 116/18639 0.0258620689655172 0.595850560504667 0.884499049506467 0.942246539136922 GO:0015605 organophosphate ester transmembrane transporter activity 1/809 50/18639 0.02 0.460791100123609 0.891572531743467 0.948749465844406 GO:0016597 amino acid binding 1/809 51/18639 0.0196078431372549 0.451755980513342 0.896291334358967 0.951701969997211 GO:0016830 carbon-carbon lyase activity 1/809 51/18639 0.0196078431372549 0.451755980513342 0.896291334358967 0.951701969997211 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/809 53/18639 0.0188679245283019 0.434708585022273 0.905122481883865 0.958998820091238 GO:0016860 intramolecular oxidoreductase activity 1/809 53/18639 0.0188679245283019 0.434708585022273 0.905122481883865 0.958998820091238 GO:0017069 snRNA binding 1/809 54/18639 0.0185185185185185 0.426658426040379 0.909252252257047 0.961293687861392 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/809 54/18639 0.0185185185185185 0.426658426040379 0.909252252257047 0.961293687861392 GO:0031406 carboxylic acid binding 5/809 187/18639 0.0267379679144385 0.616030882518194 0.912792391744269 0.96338925112036 GO:0098632 cell-cell adhesion mediator activity 1/809 55/18639 0.0181818181818182 0.418901000112372 0.91320247705791 0.96338925112036 GO:0046943 carboxylic acid transmembrane transporter activity 5/809 188/18639 0.0265957446808511 0.6127541225048 0.915044965712947 0.964293887441308 GO:0005342 organic acid transmembrane transporter activity 5/809 189/18639 0.0264550264550265 0.609512037200541 0.917246219236129 0.965111473605248 GO:0004519 endonuclease activity 3/809 127/18639 0.0236220472440945 0.544241456838909 0.917792422805399 0.965111473605248 GO:0004601 peroxidase activity 1/809 57/18639 0.0175438596491228 0.404202719406675 0.920595138449728 0.965983537558718 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/809 57/18639 0.0175438596491228 0.404202719406675 0.920595138449728 0.965983537558718 GO:0046873 metal ion transmembrane transporter activity 14/809 450/18639 0.0311111111111111 0.716786155747837 0.927084515746386 0.970999286041638 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/809 59/18639 0.0169491525423729 0.390500932308144 0.927358868691452 0.970999286041638 GO:0015081 sodium ion transmembrane transporter activity 4/809 164/18639 0.024390243902439 0.561940366004402 0.929418167865638 0.97119489466113 GO:0042626 ATPase-coupled transmembrane transporter activity 2/809 98/18639 0.0204081632653061 0.470195000126132 0.930107624130358 0.97119489466113 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/809 60/18639 0.0166666666666667 0.383992583436341 0.930521768327007 0.97119489466113 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/809 61/18639 0.0163934426229508 0.377697623052139 0.933547113578283 0.972042832855536 GO:0016836 hydro-lyase activity 1/809 61/18639 0.0163934426229508 0.377697623052139 0.933547113578283 0.972042832855536 GO:0015291 secondary active transmembrane transporter activity 8/809 287/18639 0.0278745644599303 0.642217561147888 0.934377857317997 0.972042832855536 GO:0016874 ligase activity 4/809 167/18639 0.0239520958083832 0.55184562889055 0.935305769713907 0.972042832855536 GO:0099094 ligand-gated monoatomic cation channel activity 3/809 136/18639 0.0220588235294118 0.50822547807751 0.938247841238854 0.974066422664727 GO:0015171 amino acid transmembrane transporter activity 2/809 102/18639 0.0196078431372549 0.451755980513342 0.939570063670362 0.974405818149666 GO:0005125 cytokine activity 6/809 234/18639 0.0256410256410256 0.590757820671294 0.943618655419185 0.976300391536785 GO:0019843 rRNA binding 1/809 65/18639 0.0153846153846154 0.354454692402776 0.944388632058565 0.976300391536785 GO:0160215 deacylase activity 1/809 65/18639 0.0153846153846154 0.354454692402776 0.944388632058565 0.976300391536785 GO:0003777 microtubule motor activity 1/809 68/18639 0.0147058823529412 0.338816985385007 0.951343631127502 0.981417718518256 GO:0140223 general transcription initiation factor activity 1/809 68/18639 0.0147058823529412 0.338816985385007 0.951343631127502 0.981417718518256 GO:0043022 ribosome binding 2/809 112/18639 0.0178571428571429 0.411420625110366 0.958186424786355 0.98743632617457 GO:0019842 vitamin binding 3/809 150/18639 0.02 0.460791100123609 0.96091754310838 0.988315480898813 GO:0004521 RNA endonuclease activity 1/809 73/18639 0.0136986301369863 0.315610342550417 0.961058567738171 0.988315480898813 GO:0048029 monosaccharide binding 1/809 74/18639 0.0135135135135135 0.311345337921358 0.962755412438151 0.989021562200367 GO:0005506 iron ion binding 3/809 154/18639 0.0194805194805195 0.448822500120399 0.965791656029387 0.991100661690534 GO:0016835 carbon-oxygen lyase activity 1/809 79/18639 0.0126582278481013 0.291639936787095 0.970194018803661 0.994386474450701 GO:0000049 tRNA binding 1/809 80/18639 0.0125 0.287994437577256 0.971493212703867 0.994386474450701 GO:0015079 potassium ion transmembrane transporter activity 3/809 160/18639 0.01875 0.431991656365884 0.972040710979899 0.994386474450701 GO:0008514 organic anion transmembrane transporter activity 6/809 269/18639 0.0223048327137546 0.513893420212204 0.978007206593121 0.999445777927626 GO:0005261 monoatomic cation channel activity 8/809 341/18639 0.0234604105571848 0.540517419499835 0.982505249449028 0.999999993218631 GO:0022843 voltage-gated monoatomic cation channel activity 2/809 143/18639 0.013986013986014 0.322231538547979 0.987093314985836 0.999999993218631 GO:0005249 voltage-gated potassium channel activity 1/809 98/18639 0.0102040816326531 0.235097500063066 0.987224640506145 0.999999993218631 GO:0015276 ligand-gated monoatomic ion channel activity 3/809 186/18639 0.0161290322580645 0.371605725906137 0.988606672008092 0.999999993218631 GO:0022834 ligand-gated channel activity 3/809 188/18639 0.0159574468085106 0.36765247350288 0.989382049268113 0.999999993218631 GO:0015399 primary active transmembrane transporter activity 2/809 166/18639 0.0120481927710843 0.277585000074464 0.99473963224547 0.999999993218631 GO:0022853 active monoatomic ion transmembrane transporter activity 1/809 118/18639 0.00847457627118644 0.195250466154072 0.994768077381521 0.999999993218631 GO:0051082 unfolded protein binding 1/809 121/18639 0.00826446280991736 0.190409545505624 0.995424193888248 0.999999993218631 GO:0022804 active transmembrane transporter activity 10/809 457/18639 0.0218818380743982 0.504147811951433 0.995600163445526 0.999999993218631 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/809 122/18639 0.00819672131147541 0.188848811526069 0.995624098151365 0.999999993218631 GO:0005267 potassium channel activity 1/809 124/18639 0.00806451612903226 0.185802862953068 0.995998118043232 0.999999993218631 GO:0005244 voltage-gated monoatomic ion channel activity 2/809 173/18639 0.0115606936416185 0.26635323706567 0.996010686932429 0.999999993218631 GO:0022832 voltage-gated channel activity 2/809 175/18639 0.0114285714285714 0.263309200070634 0.996314770982735 0.999999993218631 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/809 132/18639 0.00757575757575758 0.174542083380155 0.997200965798472 0.999999993218631 GO:0015078 proton transmembrane transporter activity 2/809 185/18639 0.0108108108108108 0.249076270337086 0.997524983002537 0.999999993218631 GO:0022836 gated channel activity 5/809 318/18639 0.0157232704402516 0.362257154185228 0.998334497571661 0.999999993218631 GO:0005216 monoatomic ion channel activity 8/809 448/18639 0.0178571428571429 0.411420625110366 0.999156371710228 0.999999993218631 GO:0003735 structural constituent of ribosome 1/809 175/18639 0.00571428571428571 0.131654600035317 0.999591371004837 0.999999993218631 GO:0045182 translation regulator activity 4/809 356/18639 0.0112359550561798 0.258871404563826 0.99989505082798 0.999999993218631 GO:0030371 translation repressor activity 2/809 329/18639 0.0060790273556231 0.140058085143954 0.999993517665567 0.999999993218631 GO:0004984 olfactory receptor activity 1/809 419/18639 0.00238663484486874 0.0549870047880202 0.999999993218631 0.999999993218631