category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	2/6	50/9376	62.5066666666667	HLA-DRB5/CXCR4	11.0344567245687
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	2/6	73/9376	42.8127853881278	CD4/CXCR4	9.07508051600172
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	2/6	82/9376	38.1138211382114	HLA-DRB5/CD4	8.54147217592492
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/6	93/9376	33.6057347670251	HLA-DRB5/CD4	7.99618361950408
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/6	100/9376	31.2533333333333	HLA-DRB5/CD4	7.69634151067806
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/6	109/9376	28.6727828746177	HLA-DRB5/CD4	7.35339627839314
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/6	160/9376	19.5333333333333	HLA-DRB5/CD4	5.98320334616108
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/6	214/9376	14.6043613707165	CD4/CXCR4	5.09426309407997
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/6	224/9376	13.952380952381	HLA-DRB5/CD4	4.96486084596005
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/6	298/9376	10.4876957494407	CD4/CXCR4	4.21177594757006
Organismal Systems	Excretory system	hsa04964	Proximal tubule bicarbonate reclamation	1/6	23/9376	67.9420289855072	ATP1B3	8.13352470776726
Human Diseases	Immune disease	hsa05310	Asthma	1/6	32/9376	48.8333333333333	HLA-DRB5	6.85852440860957
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/6	38/9376	41.1228070175439	ATP1B3	6.27115652073403
Human Diseases	Immune disease	hsa05340	Primary immunodeficiency	1/6	38/9376	41.1228070175439	CD4	6.27115652073403
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/6	39/9376	40.0683760683761	HLA-DRB5	6.18650618713445
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/6	44/9376	35.5151515151515	HLA-DRB5	5.80684488778931
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/6	45/9376	34.7259259259259	HLA-DRB5	5.73848845095336
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/6	48/9376	32.5555555555556	ATP1B3	5.54617601734487
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/6	53/9376	29.4842767295597	ATP1B3	5.26207164663106
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/6	54/9376	28.9382716049383	HLA-DRB5	5.20994733981975
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	2/6	480/9376	6.51111111111111	UBC/ATXN1	3.13656192755094
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/6	61/9376	25.6174863387978	ATP1B3	4.88099835647932
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/6	62/9376	25.2043010752688	ATXN1	4.83851110719158
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/6	66/9376	23.6767676767677	HLA-DRB5	4.6781026372624
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/6	70/9376	22.3238095238095	HLA-DRB5	4.53130983129127
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/6	75/9376	20.8355555555556	ATP1B3	4.36416986553862
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/6	76/9376	20.5614035087719	UBC	4.33268186675042
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/6	76/9376	20.5614035087719	ATP1B3	4.33268186675042
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/6	78/9376	20.034188034188	HLA-DRB5	4.27147976803138
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/6	86/9376	18.1705426356589	ATP1B3	4.0477795955268
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	1/6	87/9376	17.9616858237548	ATP1B3	4.02194037071091
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/6	90/9376	17.362962962963	ATP1B3	3.94693823622191
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/6	90/9376	17.362962962963	CD4	3.94693823622191
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/6	93/9376	16.8028673835125	ATP1B3	3.87547252703018
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/6	95/9376	16.4491228070175	HLA-DRB5	3.82965551164386
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/6	98/9376	15.9455782312925	ATP1B3	3.76348373874183
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/6	99/9376	15.7845117845118	HLA-DRB5	3.74207316641307
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/6	100/9376	15.6266666666667	CXCR4	3.72097251529917
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/6	102/9376	15.3202614379085	ATP1B3	3.67967070112333
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/6	103/9376	15.1715210355987	ATP1B3	3.65945504323196
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/6	105/9376	14.8825396825397	UBC	3.61985980171489
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/6	112/9376	13.952380952381	HLA-DRB5	3.48940047130341
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/6	116/9376	13.4712643678161	CXCR4	3.41999487135691
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/6	122/9376	12.8087431693989	CD4	3.32208173059216
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/6	122/9376	12.8087431693989	ATP1B3	3.32208173059216
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/6	138/9376	11.3236714975845	CD4	3.09154953098064
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/6	142/9376	11.0046948356808	UBC	3.03979678478466
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/6	143/9376	10.9277389277389	HLA-DRB5	3.02718119442758
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/6	144/9376	10.8518518518519	ATXN1	3.01469019581253
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/6	154/9376	10.1471861471861	ATP1B3	2.89618824557166
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	1/6	155/9376	10.0817204301075	HLA-DRB5	2.88493767023008
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/6	166/9376	9.4136546184739	ATP1B3	2.76758123357608
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/6	169/9376	9.2465483234714	UBC	2.73746110274869
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/6	173/9376	9.03275529865125	HLA-DRB5	2.69844981615156
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/6	180/9376	8.68148148148148	HLA-DRB5	2.63313561404458
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/6	181/9376	8.63351749539595	HLA-DRB5	2.62409524265397
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/6	184/9376	8.4927536231884	CXCR4	2.59738796542852
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/6	193/9376	8.09671848013817	CXCR4	2.52078268950468
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/6	196/9376	7.97278911564626	UBC	2.49634550653216
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/6	205/9376	7.62276422764228	HLA-DRB5	2.42604775877127
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/6	226/9376	6.91445427728614	ATP1B3	2.27745507704411
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/6	227/9376	6.88399412628488	CXCR4	2.27085713856627
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	1/6	232/9376	6.73563218390805	CXCR4	2.23845642558385
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	1/6	233/9376	6.70672389127325	ATP1B3	2.23209116850513
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/6	250/9376	6.25066666666667	CXCR4	2.12929428510072
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	1/6	253/9376	6.17654808959157	UBC	2.11214215278943
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/6	254/9376	6.15223097112861	CXCR4	2.10648618983837
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	1/6	268/9376	5.83084577114428	UBC	2.03034820786711