ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0005518	collagen binding	22/1215	72/18639	0.305555555555556	4.68744855967078	5.20257438120497e-10	5.79046528628113e-07
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	18/1215	68/18639	0.264705882352941	4.06078431372549	2.2344093993373e-07	9.35953320254748e-05
GO:0003712	transcription coregulator activity	63/1215	495/18639	0.127272727272727	1.95245791245791	2.52278522979716e-07	9.35953320254748e-05
GO:0005201	extracellular matrix structural constituent	30/1215	168/18639	0.178571428571429	2.73941798941799	4.10594638460404e-07	9.82136160007551e-05
GO:0022853	active monoatomic ion transmembrane transporter activity	24/1215	118/18639	0.203389830508475	3.12015065913371	5.12355948144682e-07	9.82136160007551e-05
GO:0046332	SMAD binding	19/1215	79/18639	0.240506329113924	3.68954524144398	5.29453455529677e-07	9.82136160007551e-05
GO:0005158	insulin receptor binding	10/1215	23/18639	0.434782608695652	6.66988727858293	6.97890098293677e-07	0.000110964525628695
GO:0015399	primary active transmembrane transporter activity	29/1215	166/18639	0.174698795180723	2.68000892458724	1.01961339115265e-06	0.000141853713044112
GO:0009055	electron transfer activity	23/1215	116/18639	0.198275862068966	3.04169859514687	1.40485909228134e-06	0.000173734241078793
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	15/1215	58/18639	0.258620689655172	3.96743295019157	3.11007835032585e-06	0.000346151720391268
GO:0008137	NADH dehydrogenase (ubiquinone) activity	12/1215	41/18639	0.292682926829268	4.489972899729	7.50085853540741e-06	0.000758950504537132
GO:0003714	transcription corepressor activity	31/1215	204/18639	0.151960784313725	2.33119099491649	9.02151106925264e-06	0.000836745151673182
GO:0043394	proteoglycan binding	11/1215	37/18639	0.297297297297297	4.56076076076076	1.52521212020608e-05	0.00123850896913493
GO:0003954	NADH dehydrogenase activity	12/1215	44/18639	0.272727272727273	4.18383838383838	1.6691495540902e-05	0.00123850896913493
GO:0030020	extracellular matrix structural constituent conferring tensile strength	12/1215	44/18639	0.272727272727273	4.18383838383838	1.6691495540902e-05	0.00123850896913493
GO:0048407	platelet-derived growth factor binding	6/1215	11/18639	0.545454545454545	8.36767676767677	2.63386247829856e-05	0.00183218058646644
GO:0044389	ubiquitin-like protein ligase binding	41/1215	322/18639	0.127329192546584	1.953324131585	3.04540966806931e-05	0.0019938476238595
GO:0005178	integrin binding	25/1215	161/18639	0.15527950310559	2.3821025994939	4.47349180020769e-05	0.00276610909646176
GO:0035497	cAMP response element binding	6/1215	12/18639	0.5	7.67037037037037	4.97652629765959e-05	0.00291519672068164
GO:0031625	ubiquitin protein ligase binding	38/1215	302/18639	0.125827814569536	1.93029188128526	7.5712699905019e-05	0.00421341174971431
GO:0001221	transcription coregulator binding	19/1215	115/18639	0.165217391304348	2.53455716586151	0.000154948989833069	0.00815893388797108
GO:0016651	oxidoreductase activity, acting on NAD(P)H	16/1215	88/18639	0.181818181818182	2.78922558922559	0.00016127272734534	0.00815893388797108
GO:0071889	14-3-3 protein binding	9/1215	33/18639	0.272727272727273	4.18383838383838	0.000190759110397691	0.00888730422458522
GO:0019838	growth factor binding	21/1215	136/18639	0.154411764705882	2.3687908496732	0.000191639983279466	0.00888730422458522
GO:0050840	extracellular matrix binding	13/1215	67/18639	0.194029850746269	2.97656163626313	0.000335654334210298	0.0149433309590425
GO:0042393	histone binding	31/1215	247/18639	0.125506072874494	1.92535612535613	0.000349844519123903	0.0149760365301886
GO:0003713	transcription coactivator activity	31/1215	256/18639	0.12109375	1.85766782407407	0.000647988456474092	0.0267115241502098
GO:0008201	heparin binding	23/1215	172/18639	0.133720930232558	2.05137812230835	0.000812344047892768	0.0322906759037375
GO:0051117	ATPase binding	14/1215	84/18639	0.166666666666667	2.55679012345679	0.00100394311454884	0.037738023260834
GO:0140297	DNA-binding transcription factor binding	50/1215	488/18639	0.102459016393443	1.57179720704311	0.00101719739247531	0.037738023260834
GO:0004674	protein serine/threonine kinase activity	45/1215	433/18639	0.103926096997691	1.59430331023865	0.00133489415748102	0.0479270063637542
GO:0042277	peptide binding	29/1215	249/18639	0.116465863453815	1.78667261639149	0.00174403927389321	0.0583791223013092
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	6/1215	21/18639	0.285714285714286	4.38306878306878	0.00175782853744363	0.0583791223013092
GO:0001046	core promoter sequence-specific DNA binding	9/1215	44/18639	0.204545454545455	3.13787878787879	0.00183582145601601	0.0583791223013092
GO:0001223	transcription coactivator binding	9/1215	44/18639	0.204545454545455	3.13787878787879	0.00183582145601601	0.0583791223013092
GO:0042605	peptide antigen binding	9/1215	45/18639	0.2	3.06814814814815	0.00216430223776939	0.0662248986879176
GO:0000287	magnesium ion binding	27/1215	230/18639	0.117391304347826	1.80086956521739	0.00220154649726231	0.0662248986879176
GO:0001968	fibronectin binding	7/1215	30/18639	0.233333333333333	3.57950617283951	0.00265390497572778	0.0777314799469741
GO:0005522	profilin binding	4/1215	10/18639	0.4	6.1362962962963	0.00274487590601262	0.0783345354715908
GO:0003725	double-stranded RNA binding	12/1215	75/18639	0.16	2.45451851851852	0.00319476816911545	0.0848689458679057
GO:0019003	GDP binding	12/1215	75/18639	0.16	2.45451851851852	0.00319476816911545	0.0848689458679057
GO:0044325	transmembrane transporter binding	18/1215	136/18639	0.132352941176471	2.03039215686274	0.00320260173086437	0.0848689458679057
GO:0045296	cadherin binding	35/1215	334/18639	0.104790419161677	1.60756265247283	0.00379097793196609	0.0959445504836513
GO:1901681	sulfur compound binding	30/1215	275/18639	0.109090909090909	1.67353535353535	0.00394994334678243	0.0959445504836513
GO:0001222	transcription corepressor binding	9/1215	49/18639	0.183673469387755	2.81768707482993	0.0039722222111757	0.0959445504836513
GO:0034056	estrogen response element binding	4/1215	11/18639	0.363636363636364	5.57845117845118	0.00409223774498182	0.0959445504836513
GO:0050786	RAGE receptor binding	4/1215	11/18639	0.363636363636364	5.57845117845118	0.00409223774498182	0.0959445504836513
GO:0005543	phospholipid binding	48/1215	497/18639	0.096579476861167	1.48160071540353	0.00413777037126259	0.0959445504836513
GO:1990841	promoter-specific chromatin binding	11/1215	68/18639	0.161764705882353	2.48159041394336	0.0042793373711469	0.097202091716051
GO:0005539	glycosaminoglycan binding	27/1215	242/18639	0.111570247933884	1.71157024793388	0.00447103723162018	0.0995252887758652
GO:0015078	proton transmembrane transporter activity	22/1215	185/18639	0.118918918918919	1.8243043043043	0.00460596868672551	0.100518493104421
GO:0003697	single-stranded DNA binding	16/1215	121/18639	0.132231404958678	2.02852770125497	0.00531662366407464	0.113796194963751
GO:0070412	R-SMAD binding	6/1215	26/18639	0.230769230769231	3.54017094017094	0.00563876850528234	0.116221284192208
GO:0097602	cullin family protein binding	6/1215	26/18639	0.230769230769231	3.54017094017094	0.00563876850528234	0.116221284192208
GO:0008179	adenylate cyclase binding	4/1215	12/18639	0.333333333333333	5.11358024691358	0.0058244219075502	0.117865119692789
GO:0019902	phosphatase binding	22/1215	190/18639	0.115789473684211	1.7762962962963	0.00630745852435285	0.125360738171513
GO:0008266	poly(U) RNA binding	6/1215	27/18639	0.222222222222222	3.40905349794239	0.00685725977456718	0.133897019808654
GO:0005507	copper ion binding	10/1215	63/18639	0.158730158730159	2.43503821281599	0.00722826575768669	0.138707927384574
GO:0106310	protein serine kinase activity	36/1215	361/18639	0.0997229916897507	1.52982456140351	0.00736150963007595	0.138870512174145
GO:0016004	phospholipase activator activity	5/1215	20/18639	0.25	3.83518518518519	0.00793998903381715	0.147286796577308
GO:0097718	disordered domain specific binding	6/1215	28/18639	0.214285714285714	3.28730158730159	0.00825554117684633	0.150629792292294
GO:0140030	modification-dependent protein binding	20/1215	173/18639	0.115606936416185	1.77349603939199	0.00907245442509306	0.162865189921429
GO:0051010	microtubule plus-end binding	5/1215	21/18639	0.238095238095238	3.65255731922399	0.00987191418893388	0.171678757691928
GO:0072542	protein phosphatase activator activity	5/1215	21/18639	0.238095238095238	3.65255731922399	0.00987191418893388	0.171678757691928
GO:0140996	histone H3 kinase activity	35/1215	357/18639	0.0980392156862745	1.5039941902687	0.0104569915332676	0.178899289730337
GO:0008191	metalloendopeptidase inhibitor activity	4/1215	14/18639	0.285714285714286	4.38306878306878	0.0106085832185106	0.178899289730337
GO:0008187	poly-pyrimidine tract binding	6/1215	30/18639	0.2	3.06814814814815	0.0116455432300629	0.187543193782911
GO:0035925	mRNA 3'-UTR AU-rich region binding	6/1215	30/18639	0.2	3.06814814814815	0.0116455432300629	0.187543193782911
GO:0032266	phosphatidylinositol-3-phosphate binding	8/1215	48/18639	0.166666666666667	2.55679012345679	0.0116750365292716	0.187543193782911
GO:0035173	histone kinase activity	35/1215	360/18639	0.0972222222222222	1.49146090534979	0.0117951694203088	0.187543193782911
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	34/1215	349/18639	0.0974212034383954	1.49451342459938	0.0125600005622284	0.191045770007332
GO:0016763	pentosyltransferase activity	8/1215	49/18639	0.163265306122449	2.50461073318216	0.0131780246889001	0.191045770007332
GO:0016247	channel regulator activity	19/1215	168/18639	0.113095238095238	1.73496472663139	0.0134433234377754	0.191045770007332
GO:0070325	lipoprotein particle receptor binding	6/1215	31/18639	0.193548387096774	2.96917562724014	0.0136633346938763	0.191045770007332
GO:0004129	cytochrome-c oxidase activity	4/1215	15/18639	0.266666666666667	4.09086419753086	0.0137319511236178	0.191045770007332
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/1215	15/18639	0.266666666666667	4.09086419753086	0.0137319511236178	0.191045770007332
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/1215	15/18639	0.266666666666667	4.09086419753086	0.0137319511236178	0.191045770007332
GO:0031386	protein tag activity	4/1215	15/18639	0.266666666666667	4.09086419753086	0.0137319511236178	0.191045770007332
GO:0050780	dopamine receptor binding	4/1215	15/18639	0.266666666666667	4.09086419753086	0.0137319511236178	0.191045770007332
GO:0141047	molecular tag activity	4/1215	15/18639	0.266666666666667	4.09086419753086	0.0137319511236178	0.191045770007332
GO:0031681	G-protein beta-subunit binding	5/1215	23/18639	0.217391304347826	3.33494363929147	0.0146533139296847	0.198891931752915
GO:0070577	lysine-acetylated histone binding	5/1215	23/18639	0.217391304347826	3.33494363929147	0.0146533139296847	0.198891931752915
GO:0141108	transporter regulator activity	19/1215	170/18639	0.111764705882353	1.71455337690632	0.015099017434652	0.200088963387311
GO:0098531	ligand-modulated transcription factor activity	9/1215	60/18639	0.15	2.30111111111111	0.0151010538405517	0.200088963387311
GO:0141003	histone H2AX kinase activity	34/1215	354/18639	0.096045197740113	1.47340447792425	0.0152844276766529	0.200136094166055
GO:0002020	protease binding	16/1215	136/18639	0.117647058823529	1.80479302832244	0.0156973705776246	0.200504066586965
GO:0099106	ion channel regulator activity	18/1215	160/18639	0.1125	1.72583333333333	0.0166377169660192	0.200504066586965
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	4/1215	16/18639	0.25	3.83518518518519	0.0173822951240763	0.200504066586965
GO:0005024	transforming growth factor beta receptor activity	4/1215	16/18639	0.25	3.83518518518519	0.0173822951240763	0.200504066586965
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/1215	16/18639	0.25	3.83518518518519	0.0173822951240763	0.200504066586965
GO:0030275	LRR domain binding	4/1215	16/18639	0.25	3.83518518518519	0.0173822951240763	0.200504066586965
GO:0070411	I-SMAD binding	4/1215	16/18639	0.25	3.83518518518519	0.0173822951240763	0.200504066586965
GO:0017124	SH3 domain binding	14/1215	115/18639	0.121739130434783	1.86756843800322	0.0174430463544827	0.200504066586965
GO:0035035	histone acetyltransferase binding	5/1215	24/18639	0.208333333333333	3.19598765432099	0.0175395229059305	0.200504066586965
GO:0050431	transforming growth factor beta binding	5/1215	24/18639	0.208333333333333	3.19598765432099	0.0175395229059305	0.200504066586965
GO:0060229	lipase activator activity	5/1215	24/18639	0.208333333333333	3.19598765432099	0.0175395229059305	0.200504066586965
GO:0140033	acetylation-dependent protein binding	5/1215	24/18639	0.208333333333333	3.19598765432099	0.0175395229059305	0.200504066586965
GO:0035198	miRNA binding	7/1215	42/18639	0.166666666666667	2.55679012345679	0.017834593523908	0.200504066586965
GO:0048487	beta-tubulin binding	7/1215	42/18639	0.166666666666667	2.55679012345679	0.017834593523908	0.200504066586965
GO:0042826	histone deacetylase binding	15/1215	127/18639	0.118110236220472	1.81189851268591	0.018313164877269	0.203825525084004
GO:0042562	hormone binding	12/1215	94/18639	0.127659574468085	1.95839243498818	0.0189105369264802	0.208390372269034
GO:0035403	histone H3T6 kinase activity	25/1215	247/18639	0.101214574898785	1.55270655270655	0.019253992610648	0.210095037016189
GO:0017046	peptide hormone binding	8/1215	53/18639	0.150943396226415	2.31558350803634	0.020620399804556	0.218421818139458
GO:0019211	phosphatase activator activity	5/1215	25/18639	0.2	3.06814814814815	0.0207778447258536	0.218421818139458
GO:0031491	nucleosome binding	10/1215	74/18639	0.135135135135135	2.07307307307307	0.021393430583869	0.218421818139458
GO:0004029	aldehyde dehydrogenase (NAD+) activity	4/1215	17/18639	0.235294117647059	3.60958605664488	0.021582876852112	0.218421818139458
GO:0048038	quinone binding	4/1215	17/18639	0.235294117647059	3.60958605664488	0.021582876852112	0.218421818139458
GO:0003925	G protein activity	8/1215	54/18639	0.148148148148148	2.27270233196159	0.0228696654134038	0.218421818139458
GO:0140463	chromatin-protein adaptor activity	8/1215	54/18639	0.148148148148148	2.27270233196159	0.0228696654134038	0.218421818139458
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	3/1215	10/18639	0.3	4.60222222222222	0.0234544499143932	0.218421818139458
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	3/1215	10/18639	0.3	4.60222222222222	0.0234544499143932	0.218421818139458
GO:0047429	nucleoside triphosphate diphosphatase activity	3/1215	10/18639	0.3	4.60222222222222	0.0234544499143932	0.218421818139458
GO:0050815	phosphoserine residue binding	3/1215	10/18639	0.3	4.60222222222222	0.0234544499143932	0.218421818139458
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	3/1215	10/18639	0.3	4.60222222222222	0.0234544499143932	0.218421818139458
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	3/1215	10/18639	0.3	4.60222222222222	0.0234544499143932	0.218421818139458
GO:1905394	retromer complex binding	3/1215	10/18639	0.3	4.60222222222222	0.0234544499143932	0.218421818139458
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	3/1215	10/18639	0.3	4.60222222222222	0.0234544499143932	0.218421818139458
GO:0051020	GTPase binding	30/1215	315/18639	0.0952380952380952	1.46102292768959	0.0239958741064707	0.218421818139458
GO:0005154	epidermal growth factor receptor binding	6/1215	35/18639	0.171428571428571	2.62984126984127	0.0241642762630807	0.218421818139458
GO:0050750	low-density lipoprotein particle receptor binding	5/1215	26/18639	0.192307692307692	2.95014245014245	0.0243823866831325	0.218421818139458
GO:0070006	metalloaminopeptidase activity	5/1215	26/18639	0.192307692307692	2.95014245014245	0.0243823866831325	0.218421818139458
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/1215	18/18639	0.222222222222222	3.40905349794239	0.0263518811938896	0.218421818139458
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	4/1215	18/18639	0.222222222222222	3.40905349794239	0.0263518811938896	0.218421818139458
GO:1901611	phosphatidylglycerol binding	4/1215	18/18639	0.222222222222222	3.40905349794239	0.0263518811938896	0.218421818139458
GO:0003924	GTPase activity	31/1215	331/18639	0.0936555891238671	1.43674611167058	0.0270458664453401	0.218421818139458
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	24/1215	243/18639	0.0987654320987654	1.51513488797439	0.0278201581034881	0.218421818139458
GO:0005044	scavenger receptor activity	5/1215	27/18639	0.185185185185185	2.84087791495199	0.0283653700714428	0.218421818139458
GO:0005516	calmodulin binding	21/1215	207/18639	0.101449275362319	1.55630703166935	0.0293660174358294	0.218421818139458
GO:0003727	single-stranded RNA binding	11/1215	89/18639	0.123595505617978	1.89604660840616	0.029670518137875	0.218421818139458
GO:0019199	transmembrane receptor protein kinase activity	10/1215	78/18639	0.128205128205128	1.9667616334283	0.0297230972178174	0.218421818139458
GO:0004676	3-phosphoinositide-dependent protein kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0004711	ribosomal protein S6 kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0035175	histone H3S10 kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0035979	histone H2AXS139 kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0044022	histone H3S28 kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0044023	histone H4S1 kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0044024	histone H2AS1 kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0044025	histone H2BS14 kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0072354	histone H3T3 kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0072371	histone H2AS121 kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0072518	Rho-dependent protein serine/threonine kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0140823	histone H2BS36 kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0140855	histone H3S57 kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0140995	histone H2A kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0140997	histone H4 kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0140998	histone H2B kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:1990244	histone H2AT120 kinase activity	24/1215	245/18639	0.0979591836734694	1.5027664399093	0.0302661015873463	0.218421818139458
GO:0016504	peptidase activator activity	8/1215	57/18639	0.140350877192982	2.15308641975309	0.0306417535865691	0.218421818139458
GO:0010854	adenylate cyclase regulator activity	3/1215	11/18639	0.272727272727273	4.18383838383838	0.0307152794779224	0.218421818139458
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	3/1215	11/18639	0.272727272727273	4.18383838383838	0.0307152794779224	0.218421818139458
GO:0035252	UDP-xylosyltransferase activity	3/1215	11/18639	0.272727272727273	4.18383838383838	0.0307152794779224	0.218421818139458
GO:0042285	xylosyltransferase activity	3/1215	11/18639	0.272727272727273	4.18383838383838	0.0307152794779224	0.218421818139458
GO:0042608	T cell receptor binding	3/1215	11/18639	0.272727272727273	4.18383838383838	0.0307152794779224	0.218421818139458
GO:0097493	structural molecule activity conferring elasticity	3/1215	11/18639	0.272727272727273	4.18383838383838	0.0307152794779224	0.218421818139458
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/1215	11/18639	0.272727272727273	4.18383838383838	0.0307152794779224	0.218421818139458
GO:0042805	actinin binding	6/1215	37/18639	0.162162162162162	2.48768768768769	0.0310162822238204	0.218421818139458
GO:0004677	DNA-dependent protein kinase activity	24/1215	246/18639	0.0975609756097561	1.496657633243	0.0315486250263194	0.218421818139458
GO:0140857	histone H3T45 kinase activity	24/1215	246/18639	0.0975609756097561	1.496657633243	0.0315486250263194	0.218421818139458
GO:0035091	phosphatidylinositol binding	27/1215	284/18639	0.0950704225352113	1.45845070422535	0.0315780613070733	0.218421818139458
GO:0005520	insulin-like growth factor binding	4/1215	19/18639	0.210526315789474	3.22962962962963	0.031702508910361	0.218421818139458
GO:0043395	heparan sulfate proteoglycan binding	4/1215	19/18639	0.210526315789474	3.22962962962963	0.031702508910361	0.218421818139458
GO:0005548	phospholipid transporter activity	9/1215	68/18639	0.132352941176471	2.03039215686274	0.0317918549313497	0.218421818139458
GO:0033218	amide binding	24/1215	247/18639	0.097165991902834	1.49059829059829	0.0328718141652258	0.223087372962782
GO:0035402	histone H3T11 kinase activity	24/1215	247/18639	0.097165991902834	1.49059829059829	0.0328718141652258	0.223087372962782
GO:0004679	AMP-activated protein kinase activity	24/1215	248/18639	0.0967741935483871	1.48458781362007	0.0342363834765739	0.23093996854198
GO:0140693	molecular condensate scaffold activity	7/1215	48/18639	0.145833333333333	2.23719135802469	0.0348058750024944	0.233367101673351
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	42/1215	484/18639	0.0867768595041322	1.33122130394858	0.0357331459620179	0.238149649435485
GO:0004879	nuclear receptor activity	8/1215	59/18639	0.135593220338983	2.08010043942247	0.0367269319859319	0.243315924406799
GO:0097110	scaffold protein binding	9/1215	70/18639	0.128571428571429	1.97238095238095	0.0374243903442849	0.246451844546353
GO:0042288	MHC class I protein binding	4/1215	20/18639	0.2	3.06814814814815	0.0376431388794969	0.246451844546353
GO:0004300	enoyl-CoA hydratase activity	3/1215	12/18639	0.25	3.83518518518519	0.0390122320013798	0.249847236578937
GO:0141221	histone deacetylase activity, hydrolytic mechanism	3/1215	12/18639	0.25	3.83518518518519	0.0390122320013798	0.249847236578937
GO:1990459	transferrin receptor binding	3/1215	12/18639	0.25	3.83518518518519	0.0390122320013798	0.249847236578937
GO:0061134	peptidase regulator activity	22/1215	226/18639	0.0973451327433628	1.49334644378892	0.0390596757994025	0.249847236578937
GO:0001965	G-protein alpha-subunit binding	5/1215	30/18639	0.166666666666667	2.55679012345679	0.042677841866512	0.26944356425996
GO:0030165	PDZ domain binding	10/1215	83/18639	0.120481927710843	1.84828201695672	0.0430650831537005	0.26944356425996
GO:0008013	beta-catenin binding	12/1215	106/18639	0.113207547169811	1.73668763102725	0.0430980136634545	0.26944356425996
GO:0001216	DNA-binding transcription activator activity	42/1215	491/18639	0.0855397148676171	1.312242588821	0.0433565360970782	0.26944356425996
GO:0030331	nuclear estrogen receptor binding	6/1215	40/18639	0.15	2.30111111111111	0.0434773655996495	0.26944356425996
GO:0019905	syntaxin binding	8/1215	61/18639	0.131147540983607	2.01190042501518	0.0435757785865164	0.26944356425996
GO:0009931	calcium-dependent protein serine/threonine kinase activity	4/1215	21/18639	0.19047619047619	2.92204585537919	0.0441775446890412	0.270162677136829
GO:0010314	phosphatidylinositol-5-phosphate binding	4/1215	21/18639	0.19047619047619	2.92204585537919	0.0441775446890412	0.270162677136829
GO:0042287	MHC protein binding	6/1215	41/18639	0.146341463414634	2.2449864498645	0.0482356150544493	0.287170851227246
GO:0070273	phosphatidylinositol-4-phosphate binding	5/1215	31/18639	0.161290322580645	2.47431302270012	0.0482575547843266	0.287170851227246
GO:0031994	insulin-like growth factor I binding	3/1215	13/18639	0.230769230769231	3.54017094017094	0.0483207472660608	0.287170851227246
GO:0046975	histone H3K36 methyltransferase activity	3/1215	13/18639	0.230769230769231	3.54017094017094	0.0483207472660608	0.287170851227246
GO:0070123	transforming growth factor beta receptor activity, type III	3/1215	13/18639	0.230769230769231	3.54017094017094	0.0483207472660608	0.287170851227246
GO:0019903	protein phosphatase binding	15/1215	144/18639	0.104166666666667	1.59799382716049	0.0486378655964412	0.287170851227246
GO:0031267	small GTPase binding	26/1215	283/18639	0.0918727915194346	1.40939667582777	0.0487648615291549	0.287170851227246
GO:0030159	signaling receptor complex adaptor activity	7/1215	52/18639	0.134615384615385	2.06509971509972	0.0506563726878195	0.29673969895549
GO:0022804	active transmembrane transporter activity	39/1215	457/18639	0.0853391684901532	1.30916605883783	0.051509359807182	0.300156635944469
GO:0031492	nucleosomal DNA binding	6/1215	42/18639	0.142857142857143	2.19153439153439	0.0533024519762062	0.307386679013044
GO:0042056	chemoattractant activity	6/1215	42/18639	0.142857142857143	2.19153439153439	0.0533024519762062	0.307386679013044
GO:0042626	ATPase-coupled transmembrane transporter activity	11/1215	98/18639	0.112244897959184	1.72191987906274	0.0539954696712159	0.309778132701357
GO:0051087	protein-folding chaperone binding	14/1215	134/18639	0.104477611940299	1.60276395798784	0.0543012793919843	0.30993499468348
GO:0140296	general transcription initiation factor binding	7/1215	53/18639	0.132075471698113	2.0261355695318	0.0552270642135336	0.313610828926851
GO:1902936	phosphatidylinositol bisphosphate binding	12/1215	111/18639	0.108108108108108	1.65845845845846	0.0577089507675092	0.320442630363224
GO:1901981	phosphatidylinositol phosphate binding	18/1215	185/18639	0.0972972972972973	1.49261261261261	0.0578843824293383	0.320442630363224
GO:0004705	JUN kinase activity	3/1215	14/18639	0.214285714285714	3.28730158730159	0.0586058829153928	0.320442630363224
GO:0005161	platelet-derived growth factor receptor binding	3/1215	14/18639	0.214285714285714	3.28730158730159	0.0586058829153928	0.320442630363224
GO:1901612	cardiolipin binding	3/1215	14/18639	0.214285714285714	3.28730158730159	0.0586058829153928	0.320442630363224
GO:0008200	ion channel inhibitor activity	6/1215	43/18639	0.13953488372093	2.1405684754522	0.0586800858820111	0.320442630363224
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	4/1215	23/18639	0.173913043478261	2.66795491143317	0.0590213290426424	0.320442630363224
GO:0017134	fibroblast growth factor binding	4/1215	23/18639	0.173913043478261	2.66795491143317	0.0590213290426424	0.320442630363224
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	4/1215	23/18639	0.173913043478261	2.66795491143317	0.0590213290426424	0.320442630363224
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	7/1215	54/18639	0.12962962962963	1.98861454046639	0.060046251268872	0.324424648845896
GO:0016248	channel inhibitor activity	6/1215	44/18639	0.136363636363636	2.09191919191919	0.0643696789905599	0.346103636311561
GO:0140313	molecular sequestering activity	7/1215	55/18639	0.127272727272727	1.95245791245791	0.0651154409456648	0.348430220060216
GO:0001091	RNA polymerase II general transcription initiation factor binding	4/1215	24/18639	0.166666666666667	2.55679012345679	0.0673176902699847	0.358490857753555
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	3/1215	15/18639	0.2	3.06814814814815	0.0698243658633364	0.362607970181221
GO:0051371	muscle alpha-actinin binding	3/1215	15/18639	0.2	3.06814814814815	0.0698243658633364	0.362607970181221
GO:0141050	histone H3K deacetylase activity	3/1215	15/18639	0.2	3.06814814814815	0.0698243658633364	0.362607970181221
GO:0141051	histone H4K deacetylase activity	3/1215	15/18639	0.2	3.06814814814815	0.0698243658633364	0.362607970181221
GO:0004715	non-membrane spanning protein tyrosine kinase activity	6/1215	45/18639	0.133333333333333	2.04543209876543	0.0703713580944689	0.362607970181221
GO:0140303	intramembrane lipid transporter activity	6/1215	45/18639	0.133333333333333	2.04543209876543	0.0703713580944689	0.362607970181221
GO:0141110	transporter inhibitor activity	6/1215	45/18639	0.133333333333333	2.04543209876543	0.0703713580944689	0.362607970181221
GO:0004713	protein tyrosine kinase activity	14/1215	140/18639	0.1	1.53407407407407	0.0727069167142317	0.372916121211705
GO:0140566	histone reader activity	5/1215	35/18639	0.142857142857143	2.19153439153439	0.0746725065158343	0.381240824551025
GO:0008483	transaminase activity	4/1215	25/18639	0.16	2.45451851851852	0.0761824227545812	0.385861907897082
GO:0043178	alcohol binding	10/1215	92/18639	0.108695652173913	1.66747181964573	0.0762709970686055	0.385861907897082
GO:0051219	phosphoprotein binding	10/1215	93/18639	0.10752688172043	1.64954201513341	0.0807315923877046	0.401691909140971
GO:0061980	regulatory RNA binding	7/1215	58/18639	0.120689655172414	1.8514687100894	0.0818283817492235	0.401691909140971
GO:0004707	MAP kinase activity	3/1215	16/18639	0.1875	2.87638888888889	0.0819263821877812	0.401691909140971
GO:0004708	MAP kinase kinase activity	3/1215	16/18639	0.1875	2.87638888888889	0.0819263821877812	0.401691909140971
GO:0034450	ubiquitin-ubiquitin ligase activity	3/1215	16/18639	0.1875	2.87638888888889	0.0819263821877812	0.401691909140971
GO:0140327	flippase activity	3/1215	16/18639	0.1875	2.87638888888889	0.0819263821877812	0.401691909140971
GO:0140328	floppase activity	3/1215	16/18639	0.1875	2.87638888888889	0.0819263821877812	0.401691909140971
GO:0008236	serine-type peptidase activity	18/1215	194/18639	0.0927835051546392	1.4233676975945	0.0828806337928242	0.404588357067602
GO:0000149	SNARE binding	11/1215	106/18639	0.10377358490566	1.59196366177498	0.084529295122859	0.410834521710664
GO:0005160	transforming growth factor beta receptor binding	4/1215	26/18639	0.153846153846154	2.36011396011396	0.0856006111312082	0.41423252256102
GO:0001786	phosphatidylserine binding	7/1215	59/18639	0.11864406779661	1.82008788449466	0.0878997307558204	0.418087180902684
GO:0015459	potassium channel regulator activity	7/1215	59/18639	0.11864406779661	1.82008788449466	0.0878997307558204	0.418087180902684
GO:0070063	RNA polymerase binding	7/1215	59/18639	0.11864406779661	1.82008788449466	0.0878997307558204	0.418087180902684
GO:0070888	E-box binding	7/1215	59/18639	0.11864406779661	1.82008788449466	0.0878997307558204	0.418087180902684
GO:0019888	protein phosphatase regulator activity	11/1215	107/18639	0.102803738317757	1.57708549671166	0.0889682179454988	0.421368623716341
GO:0001540	amyloid-beta binding	9/1215	83/18639	0.108433734939759	1.66345381526104	0.0905915618516367	0.427239018393524
GO:0008237	metallopeptidase activity	17/1215	184/18639	0.0923913043478261	1.41735104669887	0.092599397058104	0.428839645432306
GO:0005496	steroid binding	11/1215	108/18639	0.101851851851852	1.56248285322359	0.0935466395832815	0.428839645432306
GO:0015631	tubulin binding	32/1215	385/18639	0.0831168831168831	1.27507455507456	0.0939394071011081	0.428839645432306
GO:0001098	basal transcription machinery binding	7/1215	60/18639	0.116666666666667	1.78975308641975	0.0942189795134759	0.428839645432306
GO:0001099	basal RNA polymerase II transcription machinery binding	7/1215	60/18639	0.116666666666667	1.78975308641975	0.0942189795134759	0.428839645432306
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	3/1215	17/18639	0.176470588235294	2.70718954248366	0.0948571333311387	0.428839645432306
GO:0005092	GDP-dissociation inhibitor activity	3/1215	17/18639	0.176470588235294	2.70718954248366	0.0948571333311387	0.428839645432306
GO:0008429	phosphatidylethanolamine binding	3/1215	17/18639	0.176470588235294	2.70718954248366	0.0948571333311387	0.428839645432306
GO:0070402	NADPH binding	3/1215	17/18639	0.176470588235294	2.70718954248366	0.0948571333311387	0.428839645432306
GO:0070403	NAD+ binding	3/1215	17/18639	0.176470588235294	2.70718954248366	0.0948571333311387	0.428839645432306
GO:0008320	protein transmembrane transporter activity	4/1215	27/18639	0.148148148148148	2.27270233196159	0.0955545660981239	0.428839645432306
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	4/1215	27/18639	0.148148148148148	2.27270233196159	0.0955545660981239	0.428839645432306
GO:0017171	serine hydrolase activity	18/1215	198/18639	0.0909090909090909	1.39461279461279	0.0959632922552948	0.428944354538728
GO:0005501	retinoid binding	5/1215	38/18639	0.131578947368421	2.01851851851852	0.0986987173345738	0.435919334894368
GO:0019840	isoprenoid binding	5/1215	38/18639	0.131578947368421	2.01851851851852	0.0986987173345738	0.435919334894368
GO:0043531	ADP binding	5/1215	38/18639	0.131578947368421	2.01851851851852	0.0986987173345738	0.435919334894368
GO:0003779	actin binding	36/1215	443/18639	0.0812641083521445	1.24665161775771	0.101142936859427	0.444948967290679
GO:0004222	metalloendopeptidase activity	11/1215	110/18639	0.1	1.53407407407407	0.103121244742703	0.451865926766252
GO:0051393	alpha-actinin binding	4/1215	28/18639	0.142857142857143	2.19153439153439	0.106024148446969	0.452529058139735
GO:0051959	dynein light intermediate chain binding	4/1215	28/18639	0.142857142857143	2.19153439153439	0.106024148446969	0.452529058139735
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	4/1215	28/18639	0.142857142857143	2.19153439153439	0.106024148446969	0.452529058139735
GO:0016779	nucleotidyltransferase activity	13/1215	136/18639	0.0955882352941176	1.46639433551198	0.106472160228959	0.452529058139735
GO:0000217	DNA secondary structure binding	5/1215	39/18639	0.128205128205128	1.9667616334283	0.107474346102619	0.452529058139735
GO:0016776	phosphotransferase activity, phosphate group as acceptor	5/1215	39/18639	0.128205128205128	1.9667616334283	0.107474346102619	0.452529058139735
GO:0000400	four-way junction DNA binding	3/1215	18/18639	0.166666666666667	2.55679012345679	0.108558183758589	0.452529058139735
GO:0008525	phosphatidylcholine transporter activity	3/1215	18/18639	0.166666666666667	2.55679012345679	0.108558183758589	0.452529058139735
GO:0031690	adrenergic receptor binding	3/1215	18/18639	0.166666666666667	2.55679012345679	0.108558183758589	0.452529058139735
GO:0034185	apolipoprotein binding	3/1215	18/18639	0.166666666666667	2.55679012345679	0.108558183758589	0.452529058139735
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	3/1215	18/18639	0.166666666666667	2.55679012345679	0.108558183758589	0.452529058139735
GO:0070064	proline-rich region binding	3/1215	18/18639	0.166666666666667	2.55679012345679	0.108558183758589	0.452529058139735
GO:1990381	ubiquitin-specific protease binding	3/1215	18/18639	0.166666666666667	2.55679012345679	0.108558183758589	0.452529058139735
GO:0004175	endopeptidase activity	33/1215	405/18639	0.0814814814814815	1.24998628257888	0.109562159384809	0.455010012669002
GO:0004252	serine-type endopeptidase activity	16/1215	176/18639	0.0909090909090909	1.39461279461279	0.111482421869516	0.46126370089506
GO:0005010	insulin-like growth factor receptor activity	6/1215	51/18639	0.117647058823529	1.80479302832244	0.11281757386916	0.465059110060649
GO:0004177	aminopeptidase activity	5/1215	40/18639	0.125	1.91759259259259	0.116616771888758	0.476947348428039
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	5/1215	40/18639	0.125	1.91759259259259	0.116616771888758	0.476947348428039
GO:0043236	laminin binding	4/1215	29/18639	0.137931034482759	2.11596424010217	0.116987085463481	0.476947348428039
GO:0005096	GTPase activator activity	23/1215	271/18639	0.0848708487084871	1.30198168648353	0.117652544054516	0.477909786615607
GO:0070851	growth factor receptor binding	13/1215	139/18639	0.0935251798561151	1.43474553690381	0.120465706727952	0.483618647237451
GO:0017022	myosin binding	8/1215	76/18639	0.105263157894737	1.61481481481481	0.121031325629909	0.483618647237451
GO:0140034	methylation-dependent protein binding	8/1215	76/18639	0.105263157894737	1.61481481481481	0.121031325629909	0.483618647237451
GO:0005229	intracellularly calcium-gated chloride channel activity	3/1215	19/18639	0.157894736842105	2.42222222222222	0.122968622792631	0.483618647237451
GO:0030506	ankyrin binding	3/1215	19/18639	0.157894736842105	2.42222222222222	0.122968622792631	0.483618647237451
GO:0050145	nucleoside monophosphate kinase activity	3/1215	19/18639	0.157894736842105	2.42222222222222	0.122968622792631	0.483618647237451
GO:0070003	threonine-type peptidase activity	3/1215	19/18639	0.157894736842105	2.42222222222222	0.122968622792631	0.483618647237451
GO:0140036	ubiquitin-modified protein reader activity	3/1215	19/18639	0.157894736842105	2.42222222222222	0.122968622792631	0.483618647237451
GO:0141147	intracellularly calcium-gated channel activity	3/1215	19/18639	0.157894736842105	2.42222222222222	0.122968622792631	0.483618647237451
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	5/1215	41/18639	0.121951219512195	1.87082204155375	0.126114154782412	0.48517330403628
GO:0017080	sodium channel regulator activity	5/1215	41/18639	0.121951219512195	1.87082204155375	0.126114154782412	0.48517330403628
GO:0042169	SH2 domain binding	5/1215	41/18639	0.121951219512195	1.87082204155375	0.126114154782412	0.48517330403628
GO:0140318	protein transporter activity	5/1215	41/18639	0.121951219512195	1.87082204155375	0.126114154782412	0.48517330403628
GO:0016769	transferase activity, transferring nitrogenous groups	4/1215	30/18639	0.133333333333333	2.04543209876543	0.128419276786092	0.48517330403628
GO:0031210	phosphatidylcholine binding	4/1215	30/18639	0.133333333333333	2.04543209876543	0.128419276786092	0.48517330403628
GO:0031624	ubiquitin conjugating enzyme binding	4/1215	30/18639	0.133333333333333	2.04543209876543	0.128419276786092	0.48517330403628
GO:0070566	adenylyltransferase activity	4/1215	30/18639	0.133333333333333	2.04543209876543	0.128419276786092	0.48517330403628
GO:0005246	calcium channel regulator activity	6/1215	53/18639	0.113207547169811	1.73668763102725	0.129312598217273	0.48517330403628
GO:0016860	intramolecular oxidoreductase activity	6/1215	53/18639	0.113207547169811	1.73668763102725	0.129312598217273	0.48517330403628
GO:0038024	cargo receptor activity	7/1215	65/18639	0.107692307692308	1.65207977207977	0.129433350623839	0.48517330403628
GO:0120013	lipid transfer activity	7/1215	65/18639	0.107692307692308	1.65207977207977	0.129433350623839	0.48517330403628
GO:0035401	histone H3Y41 kinase activity	11/1215	115/18639	0.0956521739130435	1.46737520128824	0.129466730726662	0.48517330403628
GO:0140801	histone H2AXY142 kinase activity	11/1215	115/18639	0.0956521739130435	1.46737520128824	0.129466730726662	0.48517330403628
GO:0019001	guanyl nucleotide binding	32/1215	400/18639	0.08	1.22725925925926	0.134339355336956	0.494130811481882
GO:0032561	guanyl ribonucleotide binding	32/1215	400/18639	0.08	1.22725925925926	0.134339355336956	0.494130811481882
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/1215	10/18639	0.2	3.06814814814815	0.134964749946534	0.494130811481882
GO:0004090	carbonyl reductase (NADPH) activity	2/1215	10/18639	0.2	3.06814814814815	0.134964749946534	0.494130811481882
GO:0008140	cAMP response element binding protein binding	2/1215	10/18639	0.2	3.06814814814815	0.134964749946534	0.494130811481882
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/1215	10/18639	0.2	3.06814814814815	0.134964749946534	0.494130811481882
GO:0035374	chondroitin sulfate binding	2/1215	10/18639	0.2	3.06814814814815	0.134964749946534	0.494130811481882
GO:0008235	metalloexopeptidase activity	7/1215	66/18639	0.106060606060606	1.62704826038159	0.137171966578734	0.497161831838061
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	6/1215	54/18639	0.111111111111111	1.70452674897119	0.137970891585823	0.497161831838061
GO:0051287	NAD binding	6/1215	54/18639	0.111111111111111	1.70452674897119	0.137970891585823	0.497161831838061
GO:0010851	cyclase regulator activity	3/1215	20/18639	0.15	2.30111111111111	0.138026061130243	0.497161831838061
GO:0052745	inositol phosphate phosphatase activity	3/1215	20/18639	0.15	2.30111111111111	0.138026061130243	0.497161831838061
GO:0008327	methyl-CpG binding	4/1215	31/18639	0.129032258064516	1.9794504181601	0.14029508745302	0.503704620436166
GO:0019208	phosphatase regulator activity	11/1215	117/18639	0.094017094017094	1.44229186451409	0.140946392658276	0.504415868259362
GO:0019955	cytokine binding	13/1215	144/18639	0.0902777777777778	1.38492798353909	0.146008434925582	0.519593696316424
GO:0004712	protein serine/threonine/tyrosine kinase activity	5/1215	43/18639	0.116279069767442	1.78380706287683	0.146121138317197	0.519593696316424
GO:0051213	dioxygenase activity	9/1215	93/18639	0.0967741935483871	1.48458781362007	0.151742214464326	0.533333744605238
GO:0022884	macromolecule transmembrane transporter activity	4/1215	32/18639	0.125	1.91759259259259	0.152587626421185	0.533333744605238
GO:0120015	sterol transfer activity	4/1215	32/18639	0.125	1.91759259259259	0.152587626421185	0.533333744605238
GO:0005525	GTP binding	30/1215	378/18639	0.0793650793650794	1.217519106408	0.153148772061339	0.533333744605238
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	3/1215	21/18639	0.142857142857143	2.19153439153439	0.15366748053711	0.533333744605238
GO:0061891	calcium ion sensor activity	3/1215	21/18639	0.142857142857143	2.19153439153439	0.15366748053711	0.533333744605238
GO:0019205	nucleobase-containing compound kinase activity	5/1215	44/18639	0.113636363636364	1.74326599326599	0.156602094641125	0.533333744605238
GO:0030547	signaling receptor inhibitor activity	5/1215	44/18639	0.113636363636364	1.74326599326599	0.156602094641125	0.533333744605238
GO:0004016	adenylate cyclase activity	2/1215	11/18639	0.181818181818182	2.78922558922559	0.158131298939559	0.533333744605238
GO:0008046	axon guidance receptor activity	2/1215	11/18639	0.181818181818182	2.78922558922559	0.158131298939559	0.533333744605238
GO:0008432	JUN kinase binding	2/1215	11/18639	0.181818181818182	2.78922558922559	0.158131298939559	0.533333744605238
GO:0015217	ADP transmembrane transporter activity	2/1215	11/18639	0.181818181818182	2.78922558922559	0.158131298939559	0.533333744605238
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/1215	11/18639	0.181818181818182	2.78922558922559	0.158131298939559	0.533333744605238
GO:0019107	myristoyltransferase activity	2/1215	11/18639	0.181818181818182	2.78922558922559	0.158131298939559	0.533333744605238
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/1215	11/18639	0.181818181818182	2.78922558922559	0.158131298939559	0.533333744605238
GO:0043522	leucine zipper domain binding	2/1215	11/18639	0.181818181818182	2.78922558922559	0.158131298939559	0.533333744605238
GO:0048185	activin binding	2/1215	11/18639	0.181818181818182	2.78922558922559	0.158131298939559	0.533333744605238
GO:0019956	chemokine binding	4/1215	33/18639	0.121212121212121	1.85948372615039	0.165269009312841	0.551080869146844
GO:0140311	protein sequestering activity	4/1215	33/18639	0.121212121212121	1.85948372615039	0.165269009312841	0.551080869146844
GO:0051082	unfolded protein binding	11/1215	121/18639	0.0909090909090909	1.39461279461279	0.165448348685442	0.551080869146844
GO:0008276	protein methyltransferase activity	9/1215	95/18639	0.0947368421052632	1.45333333333333	0.165956158975805	0.551080869146844
GO:0003735	structural constituent of ribosome	15/1215	175/18639	0.0857142857142857	1.31492063492063	0.169066749006038	0.551080869146844
GO:0004407	histone deacetylase activity	3/1215	22/18639	0.136363636363636	2.09191919191919	0.169829953384877	0.551080869146844
GO:0008970	phospholipase A1 activity	3/1215	22/18639	0.136363636363636	2.09191919191919	0.169829953384877	0.551080869146844
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/1215	22/18639	0.136363636363636	2.09191919191919	0.169829953384877	0.551080869146844
GO:0031683	G-protein beta/gamma-subunit complex binding	3/1215	22/18639	0.136363636363636	2.09191919191919	0.169829953384877	0.551080869146844
GO:0033558	protein lysine deacetylase activity	3/1215	22/18639	0.136363636363636	2.09191919191919	0.169829953384877	0.551080869146844
GO:0050321	tau-protein kinase activity	3/1215	22/18639	0.136363636363636	2.09191919191919	0.169829953384877	0.551080869146844
GO:0140035	ubiquitin-like protein reader activity	3/1215	22/18639	0.136363636363636	2.09191919191919	0.169829953384877	0.551080869146844
GO:0140784	metal ion sensor activity	3/1215	22/18639	0.136363636363636	2.09191919191919	0.169829953384877	0.551080869146844
GO:0052866	phosphatidylinositol phosphate phosphatase activity	4/1215	34/18639	0.117647058823529	1.80479302832244	0.178310604547732	0.551814822943234
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	5/1215	46/18639	0.108695652173913	1.66747181964573	0.178441510371056	0.551814822943234
GO:0043021	ribonucleoprotein complex binding	15/1215	177/18639	0.0847457627118644	1.30006277463905	0.179881558079986	0.551814822943234
GO:0005025	transforming growth factor beta receptor activity, type I	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0005026	transforming growth factor beta receptor activity, type II	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0005049	nuclear export signal receptor activity	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0005165	neurotrophin receptor binding	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0005247	voltage-gated chloride channel activity	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0010853	cyclase activator activity	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0015368	calcium:monoatomic cation antiporter activity	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0016273	arginine N-methyltransferase activity	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0016274	protein-arginine N-methyltransferase activity	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0016361	activin receptor activity, type I	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0016362	activin receptor activity, type II	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0017002	activin receptor activity	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0035259	nuclear glucocorticoid receptor binding	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0070410	co-SMAD binding	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0070679	inositol 1,4,5 trisphosphate binding	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:1990817	poly(A) RNA polymerase activity	2/1215	12/18639	0.166666666666667	2.55679012345679	0.181955112327194	0.551814822943234
GO:0016922	nuclear receptor binding	12/1215	137/18639	0.0875912408759124	1.34371451743715	0.182766468401823	0.552769237313123
GO:0031593	polyubiquitin modification-dependent protein binding	6/1215	59/18639	0.101694915254237	1.56007532956686	0.18501440562533	0.553387301203476
GO:0036002	pre-mRNA binding	6/1215	59/18639	0.101694915254237	1.56007532956686	0.18501440562533	0.553387301203476
GO:0045309	protein phosphorylated amino acid binding	6/1215	59/18639	0.101694915254237	1.56007532956686	0.18501440562533	0.553387301203476
GO:0042171	lysophosphatidic acid acyltransferase activity	3/1215	23/18639	0.130434782608696	2.00096618357488	0.186451247036212	0.553387301203476
GO:0043274	phospholipase binding	3/1215	23/18639	0.130434782608696	2.00096618357488	0.186451247036212	0.553387301203476
GO:0044013	histone H2B acetyltransferase activity	3/1215	23/18639	0.130434782608696	2.00096618357488	0.186451247036212	0.553387301203476
GO:0071617	lysophospholipid acyltransferase activity	3/1215	23/18639	0.130434782608696	2.00096618357488	0.186451247036212	0.553387301203476
GO:0008170	N-methyltransferase activity	9/1215	98/18639	0.0918367346938776	1.40884353741497	0.188394656460768	0.557668225108604
GO:0140359	ABC-type transporter activity	5/1215	47/18639	0.106382978723404	1.63199369582348	0.189767116513333	0.558758731955925
GO:0140938	histone H3 methyltransferase activity	5/1215	47/18639	0.106382978723404	1.63199369582348	0.189767116513333	0.558758731955925
GO:0010485	histone H4 acetyltransferase activity	4/1215	35/18639	0.114285714285714	1.75322751322751	0.191683262358299	0.561430186854703
GO:0061631	ubiquitin conjugating enzyme activity	4/1215	35/18639	0.114285714285714	1.75322751322751	0.191683262358299	0.561430186854703
GO:0004714	transmembrane receptor protein tyrosine kinase activity	6/1215	60/18639	0.1	1.53407407407407	0.195102786304424	0.568453929729906
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	6/1215	60/18639	0.1	1.53407407407407	0.195102786304424	0.568453929729906
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	8/1215	86/18639	0.0930232558139535	1.42704565030146	0.197253309622847	0.573219147807386
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	3/1215	24/18639	0.125	1.91759259259259	0.203470326574244	0.574406359103344
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	3/1215	24/18639	0.125	1.91759259259259	0.203470326574244	0.574406359103344
GO:0042625	ATPase-coupled ion transmembrane transporter activity	3/1215	24/18639	0.125	1.91759259259259	0.203470326574244	0.574406359103344
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	3/1215	24/18639	0.125	1.91759259259259	0.203470326574244	0.574406359103344
GO:0046961	proton-transporting ATPase activity, rotational mechanism	3/1215	24/18639	0.125	1.91759259259259	0.203470326574244	0.574406359103344
GO:0044390	ubiquitin-like protein conjugating enzyme binding	4/1215	36/18639	0.111111111111111	1.70452674897119	0.205357526470641	0.574406359103344
GO:0045505	dynein intermediate chain binding	4/1215	36/18639	0.111111111111111	1.70452674897119	0.205357526470641	0.574406359103344
GO:0015026	coreceptor activity	6/1215	61/18639	0.0983606557377049	1.50892531876138	0.205392126022046	0.574406359103344
GO:0019855	calcium channel inhibitor activity	2/1215	13/18639	0.153846153846154	2.36011396011396	0.206252269611037	0.574406359103344
GO:0031432	titin binding	2/1215	13/18639	0.153846153846154	2.36011396011396	0.206252269611037	0.574406359103344
GO:0046974	histone H3K9 methyltransferase activity	2/1215	13/18639	0.153846153846154	2.36011396011396	0.206252269611037	0.574406359103344
GO:0071837	HMG box domain binding	2/1215	13/18639	0.153846153846154	2.36011396011396	0.206252269611037	0.574406359103344
GO:0097157	pre-mRNA intronic binding	2/1215	13/18639	0.153846153846154	2.36011396011396	0.206252269611037	0.574406359103344
GO:0140333	glycerophospholipid flippase activity	2/1215	13/18639	0.153846153846154	2.36011396011396	0.206252269611037	0.574406359103344
GO:0140666	annealing activity	2/1215	13/18639	0.153846153846154	2.36011396011396	0.206252269611037	0.574406359103344
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/1215	13/18639	0.153846153846154	2.36011396011396	0.206252269611037	0.574406359103344
GO:0035064	methylated histone binding	7/1215	74/18639	0.0945945945945946	1.45115115115115	0.206457563604459	0.574406359103344
GO:0008094	ATP-dependent activity, acting on DNA	17/1215	210/18639	0.080952380952381	1.24186948853616	0.210129963947465	0.574406359103344
GO:0031490	chromatin DNA binding	11/1215	128/18639	0.0859375	1.31834490740741	0.212886146616543	0.574406359103344
GO:0030414	peptidase inhibitor activity	14/1215	169/18639	0.0828402366863905	1.27083059390752	0.213026333333039	0.574406359103344
GO:0005004	GPI-linked ephrin receptor activity	5/1215	49/18639	0.102040816326531	1.56538170823885	0.213144498032058	0.574406359103344
GO:0005008	hepatocyte growth factor receptor activity	5/1215	49/18639	0.102040816326531	1.56538170823885	0.213144498032058	0.574406359103344
GO:0005009	insulin receptor activity	5/1215	49/18639	0.102040816326531	1.56538170823885	0.213144498032058	0.574406359103344
GO:0005011	macrophage colony-stimulating factor receptor activity	5/1215	49/18639	0.102040816326531	1.56538170823885	0.213144498032058	0.574406359103344
GO:0005018	platelet-derived growth factor alpha-receptor activity	5/1215	49/18639	0.102040816326531	1.56538170823885	0.213144498032058	0.574406359103344
GO:0005020	stem cell factor receptor activity	5/1215	49/18639	0.102040816326531	1.56538170823885	0.213144498032058	0.574406359103344
GO:0008288	boss receptor activity	5/1215	49/18639	0.102040816326531	1.56538170823885	0.213144498032058	0.574406359103344
GO:0036332	placental growth factor receptor activity	5/1215	49/18639	0.102040816326531	1.56538170823885	0.213144498032058	0.574406359103344
GO:0038062	protein tyrosine kinase collagen receptor activity	5/1215	49/18639	0.102040816326531	1.56538170823885	0.213144498032058	0.574406359103344
GO:0060175	brain-derived neurotrophic factor receptor activity	5/1215	49/18639	0.102040816326531	1.56538170823885	0.213144498032058	0.574406359103344
GO:0044183	protein folding chaperone	7/1215	75/18639	0.0933333333333333	1.4318024691358	0.215931384662427	0.580511186302613
GO:0016755	aminoacyltransferase activity	37/1215	496/18639	0.0745967741935484	1.14436977299881	0.217994604441904	0.584645770467083
GO:0023023	MHC protein complex binding	4/1215	37/18639	0.108108108108108	1.65845845845846	0.219303828471306	0.586743175693662
GO:0003707	nuclear steroid receptor activity	3/1215	25/18639	0.12	1.84088888888889	0.220827768004198	0.587993554518355
GO:0017025	TBP-class protein binding	3/1215	25/18639	0.12	1.84088888888889	0.220827768004198	0.587993554518355
GO:0005006	epidermal growth factor receptor activity	5/1215	50/18639	0.1	1.53407407407407	0.225161026232676	0.593848867765329
GO:0005007	fibroblast growth factor receptor activity	5/1215	50/18639	0.1	1.53407407407407	0.225161026232676	0.593848867765329
GO:0005017	platelet-derived growth factor receptor activity	5/1215	50/18639	0.1	1.53407407407407	0.225161026232676	0.593848867765329
GO:0005019	platelet-derived growth factor beta-receptor activity	5/1215	50/18639	0.1	1.53407407407407	0.225161026232676	0.593848867765329
GO:0019887	protein kinase regulator activity	20/1215	255/18639	0.0784313725490196	1.20319535221496	0.226031303513733	0.594734848252445
GO:0005347	ATP transmembrane transporter activity	2/1215	14/18639	0.142857142857143	2.19153439153439	0.230860000726978	0.597934852778847
GO:0008195	phosphatidate phosphatase activity	2/1215	14/18639	0.142857142857143	2.19153439153439	0.230860000726978	0.597934852778847
GO:0046030	inositol trisphosphate phosphatase activity	2/1215	14/18639	0.142857142857143	2.19153439153439	0.230860000726978	0.597934852778847
GO:0061665	SUMO ligase activity	2/1215	14/18639	0.142857142857143	2.19153439153439	0.230860000726978	0.597934852778847
GO:0098821	BMP receptor activity	2/1215	14/18639	0.142857142857143	2.19153439153439	0.230860000726978	0.597934852778847
GO:1990825	sequence-specific mRNA binding	2/1215	14/18639	0.142857142857143	2.19153439153439	0.230860000726978	0.597934852778847
GO:0140658	ATP-dependent chromatin remodeler activity	13/1215	158/18639	0.0822784810126582	1.26221284575715	0.231008074299105	0.597934852778847
GO:0042162	telomeric DNA binding	4/1215	38/18639	0.105263157894737	1.61481481481481	0.233492665075627	0.602963657144254
GO:0003743	translation initiation factor activity	5/1215	51/18639	0.0980392156862745	1.5039941902687	0.237372271054798	0.604584877680338
GO:0005021	vascular endothelial growth factor receptor activity	5/1215	51/18639	0.0980392156862745	1.5039941902687	0.237372271054798	0.604584877680338
GO:0005030	neurotrophin receptor activity	5/1215	51/18639	0.0980392156862745	1.5039941902687	0.237372271054798	0.604584877680338
GO:0005048	signal sequence binding	5/1215	51/18639	0.0980392156862745	1.5039941902687	0.237372271054798	0.604584877680338
GO:0004112	cyclic-nucleotide phosphodiesterase activity	3/1215	26/18639	0.115384615384615	1.77008547008547	0.238466092813718	0.604584877680338
GO:0005227	calcium-activated cation channel activity	3/1215	26/18639	0.115384615384615	1.77008547008547	0.238466092813718	0.604584877680338
GO:0043548	phosphatidylinositol 3-kinase binding	3/1215	26/18639	0.115384615384615	1.77008547008547	0.238466092813718	0.604584877680338
GO:0052742	phosphatidylinositol kinase activity	3/1215	26/18639	0.115384615384615	1.77008547008547	0.238466092813718	0.604584877680338
GO:0072341	modified amino acid binding	8/1215	91/18639	0.0879120879120879	1.34863654863655	0.24128436031975	0.610339756899731
GO:0019207	kinase regulator activity	22/1215	287/18639	0.0766550522648084	1.17594528326236	0.244648967214692	0.617447393446604
GO:0016887	ATP hydrolysis activity	31/1215	417/18639	0.0743405275779376	1.14043876010303	0.247891293713099	0.624214954530948
GO:0005080	protein kinase C binding	5/1215	52/18639	0.0961538461538462	1.47507122507123	0.249760219397654	0.627501409005845
GO:0033293	monocarboxylic acid binding	7/1215	79/18639	0.0886075949367089	1.35930614158462	0.255275872352691	0.633678032161231
GO:0005523	tropomyosin binding	2/1215	15/18639	0.133333333333333	2.04543209876543	0.255634713782922	0.633678032161231
GO:0030553	cGMP binding	2/1215	15/18639	0.133333333333333	2.04543209876543	0.255634713782922	0.633678032161231
GO:0033130	acetylcholine receptor binding	2/1215	15/18639	0.133333333333333	2.04543209876543	0.255634713782922	0.633678032161231
GO:0120283	protein serine/threonine kinase binding	2/1215	15/18639	0.133333333333333	2.04543209876543	0.255634713782922	0.633678032161231
GO:0140776	protein-containing complex destabilizing activity	2/1215	15/18639	0.133333333333333	2.04543209876543	0.255634713782922	0.633678032161231
GO:0023026	MHC class II protein complex binding	3/1215	27/18639	0.111111111111111	1.70452674897119	0.256330033653168	0.633989616568834
GO:0005003	ephrin receptor activity	5/1215	53/18639	0.0943396226415094	1.44723969252271	0.262306846603944	0.642069400955607
GO:0005005	transmembrane-ephrin receptor activity	5/1215	53/18639	0.0943396226415094	1.44723969252271	0.262306846603944	0.642069400955607
GO:0038064	collagen receptor activity	5/1215	53/18639	0.0943396226415094	1.44723969252271	0.262306846603944	0.642069400955607
GO:0015036	disulfide oxidoreductase activity	4/1215	40/18639	0.1	1.53407407407407	0.262481201648519	0.642069400955607
GO:0050997	quaternary ammonium group binding	4/1215	40/18639	0.1	1.53407407407407	0.262481201648519	0.642069400955607
GO:0019787	ubiquitin-like protein transferase activity	35/1215	479/18639	0.0730688935281837	1.12093095182866	0.264235824372478	0.643281621866162
GO:0048306	calcium-dependent protein binding	7/1215	80/18639	0.0875	1.34231481481481	0.265429605356592	0.643281621866162
GO:0016410	N-acyltransferase activity	8/1215	94/18639	0.0851063829787234	1.30559495665879	0.269152447589288	0.643281621866162
GO:0016500	protein-hormone receptor activity	6/1215	67/18639	0.0895522388059701	1.37379767827529	0.270680912932784	0.643281621866162
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	6/1215	67/18639	0.0895522388059701	1.37379767827529	0.270680912932784	0.643281621866162
GO:0042054	histone methyltransferase activity	6/1215	67/18639	0.0895522388059701	1.37379767827529	0.270680912932784	0.643281621866162
GO:0001217	DNA-binding transcription repressor activity	21/1215	278/18639	0.0755395683453237	1.15883293365308	0.272616167518692	0.643281621866162
GO:0140789	histone phosphatase activity	11/1215	136/18639	0.0808823529411765	1.24079520697168	0.273054795447934	0.643281621866162
GO:0019789	SUMO transferase activity	3/1215	28/18639	0.107142857142857	1.64365079365079	0.274366739877911	0.643281621866162
GO:0045499	chemorepellent activity	3/1215	28/18639	0.107142857142857	1.64365079365079	0.274366739877911	0.643281621866162
GO:0051019	mitogen-activated protein kinase binding	3/1215	28/18639	0.107142857142857	1.64365079365079	0.274366739877911	0.643281621866162
GO:0051537	2 iron, 2 sulfur cluster binding	3/1215	28/18639	0.107142857142857	1.64365079365079	0.274366739877911	0.643281621866162
GO:0015485	cholesterol binding	5/1215	54/18639	0.0925925925925926	1.42043895747599	0.274994188952732	0.643281621866162
GO:0050661	NADP binding	5/1215	54/18639	0.0925925925925926	1.42043895747599	0.274994188952732	0.643281621866162
GO:0033192	calmodulin-dependent protein phosphatase activity	7/1215	81/18639	0.0864197530864197	1.32574302697759	0.275692123656927	0.643281621866162
GO:0140791	histone H2AXS140 phosphatase activity	7/1215	81/18639	0.0864197530864197	1.32574302697759	0.275692123656927	0.643281621866162
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	7/1215	81/18639	0.0864197530864197	1.32574302697759	0.275692123656927	0.643281621866162
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	7/1215	81/18639	0.0864197530864197	1.32574302697759	0.275692123656927	0.643281621866162
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	7/1215	81/18639	0.0864197530864197	1.32574302697759	0.275692123656927	0.643281621866162
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	7/1215	81/18639	0.0864197530864197	1.32574302697759	0.275692123656927	0.643281621866162
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	7/1215	81/18639	0.0864197530864197	1.32574302697759	0.275692123656927	0.643281621866162
GO:1990439	MAP kinase serine/threonine phosphatase activity	7/1215	81/18639	0.0864197530864197	1.32574302697759	0.275692123656927	0.643281621866162
GO:0001727	lipid kinase activity	4/1215	41/18639	0.0975609756097561	1.496657633243	0.277223585093503	0.644154175801814
GO:0061650	ubiquitin-like protein conjugating enzyme activity	4/1215	41/18639	0.0975609756097561	1.496657633243	0.277223585093503	0.644154175801814
GO:0000062	fatty-acyl-CoA binding	2/1215	16/18639	0.125	1.91759259259259	0.280450189725085	0.646254785018674
GO:0005159	insulin-like growth factor receptor binding	2/1215	16/18639	0.125	1.91759259259259	0.280450189725085	0.646254785018674
GO:0016722	oxidoreductase activity, acting on metal ions	2/1215	16/18639	0.125	1.91759259259259	0.280450189725085	0.646254785018674
GO:0022858	alanine transmembrane transporter activity	2/1215	16/18639	0.125	1.91759259259259	0.280450189725085	0.646254785018674
GO:0032934	sterol binding	6/1215	68/18639	0.0882352941176471	1.35359477124183	0.282039983658346	0.648575416966403
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	7/1215	82/18639	0.0853658536585366	1.30957542908762	0.286054181417012	0.655099390775997
GO:0033549	MAP kinase phosphatase activity	7/1215	82/18639	0.0853658536585366	1.30957542908762	0.286054181417012	0.655099390775997
GO:0004402	histone acetyltransferase activity	4/1215	42/18639	0.0952380952380952	1.46102292768959	0.292094112568551	0.663098494804698
GO:0019894	kinesin binding	4/1215	42/18639	0.0952380952380952	1.46102292768959	0.292094112568551	0.663098494804698
GO:0003785	actin monomer binding	3/1215	29/18639	0.103448275862069	1.58697318007663	0.292525930771884	0.663098494804698
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	3/1215	29/18639	0.103448275862069	1.58697318007663	0.292525930771884	0.663098494804698
GO:0099604	ligand-gated calcium channel activity	3/1215	29/18639	0.103448275862069	1.58697318007663	0.292525930771884	0.663098494804698
GO:0016279	protein-lysine N-methyltransferase activity	6/1215	69/18639	0.0869565217391304	1.33397745571659	0.293502385477644	0.663959664708574
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	7/1215	83/18639	0.0843373493975904	1.2937974118697	0.296506507455517	0.669395015817424
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	20/1215	268/18639	0.0746268656716418	1.14483139856274	0.297363777948081	0.669971426834442
GO:0016278	lysine N-methyltransferase activity	6/1215	70/18639	0.0857142857142857	1.31492063492063	0.305055726132055	0.670910899790534
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/1215	17/18639	0.117647058823529	1.80479302832244	0.305195930577612	0.670910899790534
GO:0008484	sulfuric ester hydrolase activity	2/1215	17/18639	0.117647058823529	1.80479302832244	0.305195930577612	0.670910899790534
GO:0008569	minus-end-directed microtubule motor activity	2/1215	17/18639	0.117647058823529	1.80479302832244	0.305195930577612	0.670910899790534
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/1215	17/18639	0.117647058823529	1.80479302832244	0.305195930577612	0.670910899790534
GO:0015278	intracellularly gated calcium channel activity	2/1215	17/18639	0.117647058823529	1.80479302832244	0.305195930577612	0.670910899790534
GO:0019198	transmembrane receptor protein phosphatase activity	2/1215	17/18639	0.117647058823529	1.80479302832244	0.305195930577612	0.670910899790534
GO:0030548	acetylcholine receptor regulator activity	2/1215	17/18639	0.117647058823529	1.80479302832244	0.305195930577612	0.670910899790534
GO:0032183	SUMO binding	2/1215	17/18639	0.117647058823529	1.80479302832244	0.305195930577612	0.670910899790534
GO:0046965	nuclear retinoid X receptor binding	2/1215	17/18639	0.117647058823529	1.80479302832244	0.305195930577612	0.670910899790534
GO:0051787	misfolded protein binding	2/1215	17/18639	0.117647058823529	1.80479302832244	0.305195930577612	0.670910899790534
GO:1901567	fatty acid derivative binding	2/1215	17/18639	0.117647058823529	1.80479302832244	0.305195930577612	0.670910899790534
GO:0030695	GTPase regulator activity	35/1215	489/18639	0.0715746421267894	1.09800802847838	0.30626087822522	0.670910899790534
GO:0017018	myosin phosphatase activity	7/1215	84/18639	0.0833333333333333	1.2783950617284	0.307039829562012	0.670910899790534
GO:0048156	tau protein binding	4/1215	43/18639	0.0930232558139535	1.42704565030146	0.307065699671254	0.670910899790534
GO:0004857	enzyme inhibitor activity	30/1215	416/18639	0.0721153846153846	1.10630341880342	0.308564903422641	0.670910899790534
GO:0060589	nucleoside-triphosphatase regulator activity	35/1215	490/18639	0.0714285714285714	1.0957671957672	0.310587513787657	0.670910899790534
GO:0022839	monoatomic ion-gated channel activity	3/1215	30/18639	0.1	1.53407407407407	0.310760003436972	0.670910899790534
GO:0048019	receptor antagonist activity	3/1215	30/18639	0.1	1.53407407407407	0.310760003436972	0.670910899790534
GO:0051721	protein phosphatase 2A binding	3/1215	30/18639	0.1	1.53407407407407	0.310760003436972	0.670910899790534
GO:0098918	structural constituent of synapse	3/1215	30/18639	0.1	1.53407407407407	0.310760003436972	0.670910899790534
GO:0004386	helicase activity	12/1215	155/18639	0.0774193548387097	1.18767025089606	0.31104225003766	0.670910899790534
GO:0043014	alpha-tubulin binding	4/1215	44/18639	0.0909090909090909	1.39461279461279	0.322112060174267	0.693444338440927
GO:0004842	ubiquitin-protein transferase activity	32/1215	449/18639	0.0712694877505568	1.09332673430669	0.325117416834338	0.693837991037956
GO:0016791	phosphatase activity	20/1215	273/18639	0.0732600732600733	1.12386379053046	0.326588211546955	0.693837991037956
GO:0008408	3'-5' exonuclease activity	5/1215	58/18639	0.0862068965517241	1.32247765006386	0.326797205778705	0.693837991037956
GO:0016411	acylglycerol O-acyltransferase activity	3/1215	31/18639	0.0967741935483871	1.48458781362007	0.32902410157811	0.693837991037956
GO:0017147	Wnt-protein binding	3/1215	31/18639	0.0967741935483871	1.48458781362007	0.32902410157811	0.693837991037956
GO:0008308	voltage-gated monoatomic anion channel activity	2/1215	18/18639	0.111111111111111	1.70452674897119	0.32977564892999	0.693837991037956
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/1215	18/18639	0.111111111111111	1.70452674897119	0.32977564892999	0.693837991037956
GO:0017128	phospholipid scramblase activity	2/1215	18/18639	0.111111111111111	1.70452674897119	0.32977564892999	0.693837991037956
GO:0035615	clathrin adaptor activity	2/1215	18/18639	0.111111111111111	1.70452674897119	0.32977564892999	0.693837991037956
GO:0050811	GABA receptor binding	2/1215	18/18639	0.111111111111111	1.70452674897119	0.32977564892999	0.693837991037956
GO:0098641	cadherin binding involved in cell-cell adhesion	2/1215	18/18639	0.111111111111111	1.70452674897119	0.32977564892999	0.693837991037956
GO:0099602	neurotransmitter receptor regulator activity	2/1215	18/18639	0.111111111111111	1.70452674897119	0.32977564892999	0.693837991037956
GO:0035591	signaling adaptor activity	10/1215	129/18639	0.0775193798449612	1.18920470858455	0.332268204038862	0.69776322848161
GO:0031406	carboxylic acid binding	14/1215	187/18639	0.0748663101604278	1.14850465438701	0.335141675367417	0.702472099216449
GO:0043539	protein serine/threonine kinase activator activity	6/1215	73/18639	0.0821917808219178	1.26088280060883	0.340138975313942	0.711606540459432
GO:0008017	microtubule binding	20/1215	276/18639	0.072463768115942	1.11164787976382	0.344479998519995	0.716581550116159
GO:0008238	exopeptidase activity	8/1215	102/18639	0.0784313725490196	1.20319535221496	0.347127365192301	0.716581550116159
GO:0070717	poly-purine tract binding	3/1215	32/18639	0.09375	1.43819444444444	0.347276150732274	0.716581550116159
GO:0140142	nucleocytoplasmic carrier activity	3/1215	32/18639	0.09375	1.43819444444444	0.347276150732274	0.716581550116159
GO:0043177	organic acid binding	14/1215	189/18639	0.0740740740740741	1.1363511659808	0.349681574317128	0.716581550116159
GO:0031072	heat shock protein binding	10/1215	131/18639	0.0763358778625954	1.17104891150693	0.349785970880236	0.716581550116159
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	5/1215	60/18639	0.0833333333333333	1.2783950617284	0.353090920695899	0.716581550116159
GO:0004721	phosphoprotein phosphatase activity	13/1215	175/18639	0.0742857142857143	1.13959788359788	0.353918553462933	0.716581550116159
GO:0003756	protein disulfide isomerase activity	2/1215	19/18639	0.105263157894737	1.61481481481481	0.35410588729909	0.716581550116159
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/1215	19/18639	0.105263157894737	1.61481481481481	0.35410588729909	0.716581550116159
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/1215	19/18639	0.105263157894737	1.61481481481481	0.35410588729909	0.716581550116159
GO:0008301	DNA binding, bending	2/1215	19/18639	0.105263157894737	1.61481481481481	0.35410588729909	0.716581550116159
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/1215	19/18639	0.105263157894737	1.61481481481481	0.35410588729909	0.716581550116159
GO:0016918	retinal binding	2/1215	19/18639	0.105263157894737	1.61481481481481	0.35410588729909	0.716581550116159
GO:0042577	lipid phosphatase activity	2/1215	19/18639	0.105263157894737	1.61481481481481	0.35410588729909	0.716581550116159
GO:0042800	histone H3K4 methyltransferase activity	2/1215	19/18639	0.105263157894737	1.61481481481481	0.35410588729909	0.716581550116159
GO:0120227	acyl-CoA binding	2/1215	19/18639	0.105263157894737	1.61481481481481	0.35410588729909	0.716581550116159
GO:1990380	K48-linked deubiquitinase activity	2/1215	19/18639	0.105263157894737	1.61481481481481	0.35410588729909	0.716581550116159
GO:0004866	endopeptidase inhibitor activity	12/1215	161/18639	0.0745341614906832	1.14340924775707	0.358285532431262	0.723723770591642
GO:0015085	calcium ion transmembrane transporter activity	11/1215	147/18639	0.0748299319727891	1.14794658604182	0.36279014075558	0.731495338153914
GO:0061733	protein-lysine-acetyltransferase activity	4/1215	47/18639	0.0851063829787234	1.30559495665879	0.367450354282569	0.739551978872513
GO:0019209	kinase activator activity	11/1215	148/18639	0.0743243243243243	1.14019019019019	0.371187799757271	0.745725669909464
GO:0001972	retinoic acid binding	2/1215	20/18639	0.1	1.53407407407407	0.378114756873406	0.750163501604459
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	2/1215	20/18639	0.1	1.53407407407407	0.378114756873406	0.750163501604459
GO:0015095	magnesium ion transmembrane transporter activity	2/1215	20/18639	0.1	1.53407407407407	0.378114756873406	0.750163501604459
GO:0016505	peptidase activator activity involved in apoptotic process	2/1215	20/18639	0.1	1.53407407407407	0.378114756873406	0.750163501604459
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	2/1215	20/18639	0.1	1.53407407407407	0.378114756873406	0.750163501604459
GO:0043024	ribosomal small subunit binding	2/1215	20/18639	0.1	1.53407407407407	0.378114756873406	0.750163501604459
GO:0140939	histone H4 methyltransferase activity	2/1215	20/18639	0.1	1.53407407407407	0.378114756873406	0.750163501604459
GO:0140713	histone chaperone activity	12/1215	164/18639	0.0731707317073171	1.12249322493225	0.3823268752071	0.754302770545154
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	4/1215	48/18639	0.0833333333333333	1.2783950617284	0.382551240077374	0.754302770545154
GO:0008376	acetylgalactosaminyltransferase activity	3/1215	34/18639	0.0882352941176471	1.35359477124183	0.383589728776781	0.754302770545154
GO:0015035	protein-disulfide reductase activity	3/1215	34/18639	0.0882352941176471	1.35359477124183	0.383589728776781	0.754302770545154
GO:0030332	cyclin binding	3/1215	34/18639	0.0882352941176471	1.35359477124183	0.383589728776781	0.754302770545154
GO:0035254	glutamate receptor binding	4/1215	49/18639	0.0816326530612245	1.25230536659108	0.397609617148068	0.777630425695792
GO:0000175	3'-5'-RNA exonuclease activity	3/1215	35/18639	0.0857142857142857	1.31492063492063	0.401580960003514	0.777630425695792
GO:0043015	gamma-tubulin binding	3/1215	35/18639	0.0857142857142857	1.31492063492063	0.401580960003514	0.777630425695792
GO:0008373	sialyltransferase activity	2/1215	21/18639	0.0952380952380952	1.46102292768959	0.401740785961438	0.777630425695792
GO:0009975	cyclase activity	2/1215	21/18639	0.0952380952380952	1.46102292768959	0.401740785961438	0.777630425695792
GO:0036122	BMP binding	2/1215	21/18639	0.0952380952380952	1.46102292768959	0.401740785961438	0.777630425695792
GO:0051428	peptide hormone receptor binding	2/1215	21/18639	0.0952380952380952	1.46102292768959	0.401740785961438	0.777630425695792
GO:0070182	DNA polymerase binding	2/1215	21/18639	0.0952380952380952	1.46102292768959	0.401740785961438	0.777630425695792
GO:0140312	cargo adaptor activity	2/1215	21/18639	0.0952380952380952	1.46102292768959	0.401740785961438	0.777630425695792
GO:0004843	cysteine-type deubiquitinase activity	8/1215	108/18639	0.0740740740740741	1.1363511659808	0.40739450472727	0.787205006530298
GO:0042578	phosphoric ester hydrolase activity	25/1215	363/18639	0.068870523415978	1.05652484440363	0.417327375526675	0.789564558331972
GO:0000993	RNA polymerase II complex binding	3/1215	36/18639	0.0833333333333333	1.2783950617284	0.419419453961047	0.789564558331972
GO:0005484	SNAP receptor activity	3/1215	36/18639	0.0833333333333333	1.2783950617284	0.419419453961047	0.789564558331972
GO:0030295	protein kinase activator activity	10/1215	139/18639	0.0719424460431655	1.10365041300293	0.420829643917448	0.789564558331972
GO:0140767	enzyme-substrate adaptor activity	10/1215	139/18639	0.0719424460431655	1.10365041300293	0.420829643917448	0.789564558331972
GO:0061135	endopeptidase regulator activity	13/1215	184/18639	0.0706521739130435	1.08385668276973	0.42326343004712	0.789564558331972
GO:0032931	histone H3K56 acetyltransferase activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0034062	5'-3' RNA polymerase activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0043992	histone H3K9 acetyltransferase activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0043993	histone H3K18 acetyltransferase activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0043994	histone H3K23 acetyltransferase activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0043999	histone H2AK5 acetyltransferase activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0044012	histone H2AK9 acetyltransferase activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0044014	histone H2BK5 acetyltransferase activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0044015	histone H2BK12 acetyltransferase activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0044016	histone H3K4 acetyltransferase activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0044017	histone H3K27 acetyltransferase activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0044018	histone H3K36 acetyltransferase activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0046972	histone H4K16 acetyltransferase activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0070034	telomerase RNA binding	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0097747	RNA polymerase activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0140517	protein-RNA adaptor activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0140908	histone H3K122 acetyltransferase activity	2/1215	22/18639	0.0909090909090909	1.39461279461279	0.424931869219094	0.789564558331972
GO:0004867	serine-type endopeptidase inhibitor activity	7/1215	95/18639	0.0736842105263158	1.13037037037037	0.425663908587288	0.78960655042942
GO:0030544	Hsp70 protein binding	4/1215	51/18639	0.0784313725490196	1.20319535221496	0.427518583025914	0.791727425803398
GO:0140097	catalytic activity, acting on DNA	23/1215	336/18639	0.068452380952381	1.0501102292769	0.434912897384612	0.804083147490155
GO:0019213	deacetylase activity	3/1215	37/18639	0.0810810810810811	1.24384384384384	0.437076715033672	0.806743588445235
GO:0043022	ribosome binding	8/1215	112/18639	0.0714285714285714	1.0957671957672	0.447596027892754	0.811361445765965
GO:0000295	adenine nucleotide transmembrane transporter activity	2/1215	23/18639	0.0869565217391304	1.33397745571659	0.447644309426988	0.811361445765965
GO:0003887	DNA-directed DNA polymerase activity	2/1215	23/18639	0.0869565217391304	1.33397745571659	0.447644309426988	0.811361445765965
GO:0008171	O-methyltransferase activity	2/1215	23/18639	0.0869565217391304	1.33397745571659	0.447644309426988	0.811361445765965
GO:0016849	phosphorus-oxygen lyase activity	2/1215	23/18639	0.0869565217391304	1.33397745571659	0.447644309426988	0.811361445765965
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	2/1215	23/18639	0.0869565217391304	1.33397745571659	0.447644309426988	0.811361445765965
GO:0019783	ubiquitin-like protein peptidase activity	9/1215	127/18639	0.0708661417322835	1.08713910761155	0.447661200213324	0.811361445765965
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	3/1215	38/18639	0.0789473684210526	1.21111111111111	0.454526776458647	0.811361445765965
GO:0004864	protein phosphatase inhibitor activity	4/1215	53/18639	0.0754716981132075	1.15779175401817	0.457027692924813	0.811361445765965
GO:0034212	protein N-acetyltransferase activity	4/1215	53/18639	0.0754716981132075	1.15779175401817	0.457027692924813	0.811361445765965
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	9/1215	128/18639	0.0703125	1.07864583333333	0.45704607279187	0.811361445765965
GO:0061659	ubiquitin-like protein ligase activity	25/1215	372/18639	0.0672043010752688	1.03096375945838	0.46702498971559	0.811361445765965
GO:0004527	exonuclease activity	6/1215	84/18639	0.0714285714285714	1.0957671957672	0.469799996269359	0.811361445765965
GO:0005315	phosphate transmembrane transporter activity	2/1215	24/18639	0.0833333333333333	1.2783950617284	0.469841944231782	0.811361445765965
GO:0015149	hexose transmembrane transporter activity	2/1215	24/18639	0.0833333333333333	1.2783950617284	0.469841944231782	0.811361445765965
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/1215	24/18639	0.0833333333333333	1.2783950617284	0.469841944231782	0.811361445765965
GO:0030215	semaphorin receptor binding	2/1215	24/18639	0.0833333333333333	1.2783950617284	0.469841944231782	0.811361445765965
GO:0043998	histone H2A acetyltransferase activity	2/1215	24/18639	0.0833333333333333	1.2783950617284	0.469841944231782	0.811361445765965
GO:0050699	WW domain binding	2/1215	24/18639	0.0833333333333333	1.2783950617284	0.469841944231782	0.811361445765965
GO:0055056	D-glucose transmembrane transporter activity	2/1215	24/18639	0.0833333333333333	1.2783950617284	0.469841944231782	0.811361445765965
GO:0002039	p53 binding	5/1215	69/18639	0.072463768115942	1.11164787976382	0.470812745768889	0.811361445765965
GO:0008080	N-acetyltransferase activity	5/1215	69/18639	0.072463768115942	1.11164787976382	0.470812745768889	0.811361445765965
GO:0017069	snRNA binding	4/1215	54/18639	0.0740740740740741	1.1363511659808	0.471590373242578	0.811361445765965
GO:0001664	G protein-coupled receptor binding	20/1215	297/18639	0.0673400673400673	1.033046514528	0.473488509551573	0.811361445765965
GO:0101005	deubiquitinase activity	8/1215	115/18639	0.0695652173913043	1.06718196457327	0.477472252593165	0.811361445765965
GO:0004532	RNA exonuclease activity	3/1215	40/18639	0.075	1.15055555555556	0.488713536378937	0.811361445765965
GO:0015144	carbohydrate transmembrane transporter activity	3/1215	40/18639	0.075	1.15055555555556	0.488713536378937	0.811361445765965
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	3/1215	40/18639	0.075	1.15055555555556	0.488713536378937	0.811361445765965
GO:0001094	TFIID-class transcription factor complex binding	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0005031	tumor necrosis factor receptor activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0005528	FK506 binding	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0008519	ammonium channel activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0015187	glycine transmembrane transporter activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0015203	polyamine transmembrane transporter activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0015279	store-operated calcium channel activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0016868	intramolecular phosphotransferase activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0031434	mitogen-activated protein kinase kinase binding	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0035256	G protein-coupled glutamate receptor binding	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0043121	neurotrophin binding	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0043208	glycosphingolipid binding	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0043422	protein kinase B binding	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0051880	G-quadruplex DNA binding	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0099122	RNA polymerase II C-terminal domain binding	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0140940	histone H2A methyltransferase activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0141109	transporter activator activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:1990259	histone H2AQ104 methyltransferase activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:1990757	ubiquitin ligase activator activity	1/1215	10/18639	0.1	1.53407407407407	0.490458688324671	0.811361445765965
GO:0004709	MAP kinase kinase kinase activity	2/1215	25/18639	0.08	1.22725925925926	0.491495350860268	0.811361445765965
GO:0005537	D-mannose binding	2/1215	25/18639	0.08	1.22725925925926	0.491495350860268	0.811361445765965
GO:0008139	nuclear localization sequence binding	2/1215	25/18639	0.08	1.22725925925926	0.491495350860268	0.811361445765965
GO:0015662	P-type ion transporter activity	2/1215	25/18639	0.08	1.22725925925926	0.491495350860268	0.811361445765965
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/1215	25/18639	0.08	1.22725925925926	0.491495350860268	0.811361445765965
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/1215	25/18639	0.08	1.22725925925926	0.491495350860268	0.811361445765965
GO:0019707	protein-cysteine S-acyltransferase activity	2/1215	25/18639	0.08	1.22725925925926	0.491495350860268	0.811361445765965
GO:0042974	nuclear retinoic acid receptor binding	2/1215	25/18639	0.08	1.22725925925926	0.491495350860268	0.811361445765965
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/1215	25/18639	0.08	1.22725925925926	0.491495350860268	0.811361445765965
GO:0120020	cholesterol transfer activity	2/1215	25/18639	0.08	1.22725925925926	0.491495350860268	0.811361445765965
GO:0140358	P-type transmembrane transporter activity	2/1215	25/18639	0.08	1.22725925925926	0.491495350860268	0.811361445765965
GO:0005319	lipid transporter activity	12/1215	178/18639	0.0674157303370786	1.03420724094881	0.495043086176836	0.811361445765965
GO:0140299	molecular sensor activity	5/1215	71/18639	0.0704225352112676	1.08033385498174	0.496205375470377	0.811361445765965
GO:0019212	phosphatase inhibitor activity	4/1215	56/18639	0.0714285714285714	1.0957671957672	0.50025765772461	0.811361445765965
GO:0008081	phosphoric diester hydrolase activity	6/1215	87/18639	0.0689655172413793	1.05798212005109	0.504227001757493	0.811361445765965
GO:0016853	isomerase activity	12/1215	180/18639	0.0666666666666667	1.02271604938272	0.510885220249361	0.811361445765965
GO:0004722	protein serine/threonine phosphatase activity	7/1215	103/18639	0.0679611650485437	1.0425746134484	0.510897530193594	0.811361445765965
GO:0004435	phosphatidylinositol phospholipase C activity	2/1215	26/18639	0.0769230769230769	1.18005698005698	0.512581122364147	0.811361445765965
GO:0005112	Notch binding	2/1215	26/18639	0.0769230769230769	1.18005698005698	0.512581122364147	0.811361445765965
GO:0008143	poly(A) binding	2/1215	26/18639	0.0769230769230769	1.18005698005698	0.512581122364147	0.811361445765965
GO:0008157	protein phosphatase 1 binding	2/1215	26/18639	0.0769230769230769	1.18005698005698	0.512581122364147	0.811361445765965
GO:0008198	ferrous iron binding	2/1215	26/18639	0.0769230769230769	1.18005698005698	0.512581122364147	0.811361445765965
GO:0015145	monosaccharide transmembrane transporter activity	2/1215	26/18639	0.0769230769230769	1.18005698005698	0.512581122364147	0.811361445765965
GO:0015216	purine nucleotide transmembrane transporter activity	2/1215	26/18639	0.0769230769230769	1.18005698005698	0.512581122364147	0.811361445765965
GO:0019865	immunoglobulin binding	2/1215	26/18639	0.0769230769230769	1.18005698005698	0.512581122364147	0.811361445765965
GO:0030247	polysaccharide binding	2/1215	26/18639	0.0769230769230769	1.18005698005698	0.512581122364147	0.811361445765965
GO:0120014	phospholipid transfer activity	2/1215	26/18639	0.0769230769230769	1.18005698005698	0.512581122364147	0.811361445765965
GO:0004197	cysteine-type endopeptidase activity	6/1215	88/18639	0.0681818181818182	1.0459595959596	0.515526620763896	0.811361445765965
GO:0043175	RNA polymerase core enzyme binding	3/1215	42/18639	0.0714285714285714	1.0957671957672	0.521819034473639	0.811361445765965
GO:0051879	Hsp90 protein binding	3/1215	42/18639	0.0714285714285714	1.0957671957672	0.521819034473639	0.811361445765965
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0002162	dystroglycan binding	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0003953	NAD+ nucleosidase activity	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0005114	type II transforming growth factor beta receptor binding	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0005536	D-glucose binding	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0008526	phosphatidylinositol transfer activity	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0019206	nucleoside kinase activity	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0019215	intermediate filament binding	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0019864	IgG binding	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0032050	clathrin heavy chain binding	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0032404	mismatch repair complex binding	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0034713	type I transforming growth factor beta receptor binding	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0045294	alpha-catenin binding	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0050998	nitric-oxide synthase binding	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0070697	activin receptor binding	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0070990	snRNP binding	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0140537	transcription regulator activator activity	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0180030	inositol phosphate kinase activity	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:1990948	ubiquitin ligase inhibitor activity	1/1215	11/18639	0.0909090909090909	1.39461279461279	0.523691427263182	0.811361445765965
GO:0000510	H3-H4 histone complex chaperone activity	10/1215	151/18639	0.0662251655629139	1.01594309541329	0.526323662559274	0.811361445765965
GO:0140584	chromatin extrusion motor activity	10/1215	151/18639	0.0662251655629139	1.01594309541329	0.526323662559274	0.811361445765965
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	10/1215	151/18639	0.0662251655629139	1.01594309541329	0.526323662559274	0.811361445765965
GO:0140849	ATP-dependent H2AZ histone chaperone activity	10/1215	151/18639	0.0662251655629139	1.01594309541329	0.526323662559274	0.811361445765965
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	11/1215	167/18639	0.0658682634730539	1.01046795298292	0.530513854096924	0.811361445765965
GO:0061630	ubiquitin protein ligase activity	23/1215	353/18639	0.0651558073654391	0.999538348546847	0.532227617114692	0.811361445765965
GO:0005104	fibroblast growth factor receptor binding	2/1215	27/18639	0.0740740740740741	1.1363511659808	0.533081209461025	0.811361445765965
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	2/1215	27/18639	0.0740740740740741	1.1363511659808	0.533081209461025	0.811361445765965
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	2/1215	27/18639	0.0740740740740741	1.1363511659808	0.533081209461025	0.811361445765965
GO:0035255	ionotropic glutamate receptor binding	2/1215	27/18639	0.0740740740740741	1.1363511659808	0.533081209461025	0.811361445765965
GO:0003684	damaged DNA binding	5/1215	74/18639	0.0675675675675676	1.03653653653654	0.533385767924784	0.811361445765965
GO:0015616	DNA translocase activity	10/1215	152/18639	0.0657894736842105	1.00925925925926	0.534870476443823	0.811361445765965
GO:0140674	ATP-dependent histone chaperone activity	10/1215	152/18639	0.0657894736842105	1.00925925925926	0.534870476443823	0.811361445765965
GO:0046982	protein heterodimerization activity	24/1215	369/18639	0.0650406504065041	0.997771755495333	0.535215673467743	0.811361445765965
GO:0005245	voltage-gated calcium channel activity	3/1215	43/18639	0.0697674418604651	1.0702842377261	0.537925534583818	0.811361445765965
GO:0008375	acetylglucosaminyltransferase activity	3/1215	43/18639	0.0697674418604651	1.0702842377261	0.537925534583818	0.811361445765965
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	4/1215	59/18639	0.0677966101694915	1.04005021971124	0.541922183168066	0.811361445765965
GO:0061775	cohesin loader activity	10/1215	153/18639	0.065359477124183	1.00266279351247	0.543363050778999	0.811361445765965
GO:0003730	mRNA 3'-UTR binding	17/1215	262/18639	0.0648854961832061	0.995391574780888	0.544037581981345	0.811361445765965
GO:0005506	iron ion binding	10/1215	154/18639	0.0649350649350649	0.996151996151996	0.551798228110713	0.811361445765965
GO:0005242	inward rectifier potassium channel activity	2/1215	28/18639	0.0714285714285714	1.0957671957672	0.55298232250588	0.811361445765965
GO:0016866	intramolecular transferase activity	2/1215	28/18639	0.0714285714285714	1.0957671957672	0.55298232250588	0.811361445765965
GO:0036408	histone H3K14 acetyltransferase activity	2/1215	28/18639	0.0714285714285714	1.0957671957672	0.55298232250588	0.811361445765965
GO:0046875	ephrin receptor binding	2/1215	28/18639	0.0714285714285714	1.0957671957672	0.55298232250588	0.811361445765965
GO:0051119	sugar transmembrane transporter activity	2/1215	28/18639	0.0714285714285714	1.0957671957672	0.55298232250588	0.811361445765965
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0003995	acyl-CoA dehydrogenase activity	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0004000	adenosine deaminase activity	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0004859	phospholipase inhibitor activity	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0005078	MAP-kinase scaffold activity	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0005527	macrolide binding	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0008504	monoamine transmembrane transporter activity	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0008603	cAMP-dependent protein kinase regulator activity	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0031543	peptidyl-proline dioxygenase activity	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0034452	dynactin binding	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0035251	UDP-glucosyltransferase activity	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0036009	protein-glutamine N-methyltransferase activity	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0042301	phosphate ion binding	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0045295	gamma-catenin binding	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0070008	serine-type exopeptidase activity	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0097371	MDM2/MDM4 family protein binding	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0097677	STAT family protein binding	1/1215	12/18639	0.0833333333333333	1.2783950617284	0.554758364984635	0.811361445765965
GO:0051536	iron-sulfur cluster binding	5/1215	76/18639	0.0657894736842105	1.00925925925926	0.557466293878801	0.81425194893321
GO:0140104	molecular carrier activity	16/1215	249/18639	0.0642570281124498	0.985750409043582	0.560897398967149	0.818189783814465
GO:0008234	cysteine-type peptidase activity	12/1215	187/18639	0.0641711229946524	0.984432560903149	0.565119380500525	0.819065661441991
GO:0016836	hydro-lyase activity	4/1215	61/18639	0.0655737704918033	1.00595021250759	0.568682538726806	0.819065661441991
GO:0051539	4 iron, 4 sulfur cluster binding	3/1215	45/18639	0.0666666666666667	1.02271604938272	0.569181691910233	0.819065661441991
GO:0003724	RNA helicase activity	5/1215	77/18639	0.0649350649350649	0.996151996151996	0.569272227464002	0.819065661441991
GO:0051540	metal cluster binding	5/1215	77/18639	0.0649350649350649	0.996151996151996	0.569272227464002	0.819065661441991
GO:0004620	phospholipase activity	7/1215	109/18639	0.0642201834862385	0.985185185185185	0.571804539793645	0.819065661441991
GO:0004629	phospholipase C activity	2/1215	29/18639	0.0689655172413793	1.05798212005109	0.57227538856025	0.819065661441991
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	2/1215	29/18639	0.0689655172413793	1.05798212005109	0.57227538856025	0.819065661441991
GO:0010484	histone H3 acetyltransferase activity	2/1215	29/18639	0.0689655172413793	1.05798212005109	0.57227538856025	0.819065661441991
GO:0016417	S-acyltransferase activity	2/1215	29/18639	0.0689655172413793	1.05798212005109	0.57227538856025	0.819065661441991
GO:0097472	cyclin-dependent protein kinase activity	2/1215	29/18639	0.0689655172413793	1.05798212005109	0.57227538856025	0.819065661441991
GO:0106222	lncRNA binding	2/1215	29/18639	0.0689655172413793	1.05798212005109	0.57227538856025	0.819065661441991
GO:0140597	protein carrier chaperone	12/1215	188/18639	0.0638297872340425	0.97919621749409	0.572679744029682	0.819065661441991
GO:0016757	glycosyltransferase activity	17/1215	267/18639	0.0636704119850187	0.976751283118324	0.576104188261131	0.819065661441991
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0004465	lipoprotein lipase activity	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0004535	poly(A)-specific ribonuclease activity	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0005035	death receptor activity	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0005172	vascular endothelial growth factor receptor binding	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0005542	folic acid binding	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0008035	high-density lipoprotein particle binding	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0017154	semaphorin receptor activity	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0019104	DNA N-glycosylase activity	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0035673	oligopeptide transmembrane transporter activity	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0039706	co-receptor binding	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0043560	insulin receptor substrate binding	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0045159	myosin II binding	1/1215	13/18639	0.0769230769230769	1.18005698005698	0.583800539599102	0.819065661441991
GO:0030291	protein serine/threonine kinase inhibitor activity	3/1215	46/18639	0.0652173913043478	1.00048309178744	0.584310992978383	0.819065661441991
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/1215	30/18639	0.0666666666666667	1.02271604938272	0.590955058926199	0.822098591073357
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/1215	30/18639	0.0666666666666667	1.02271604938272	0.590955058926199	0.822098591073357
GO:0015215	nucleotide transmembrane transporter activity	2/1215	30/18639	0.0666666666666667	1.02271604938272	0.590955058926199	0.822098591073357
GO:0043995	histone H4K5 acetyltransferase activity	2/1215	30/18639	0.0666666666666667	1.02271604938272	0.590955058926199	0.822098591073357
GO:0043996	histone H4K8 acetyltransferase activity	2/1215	30/18639	0.0666666666666667	1.02271604938272	0.590955058926199	0.822098591073357
GO:0043997	histone H4K12 acetyltransferase activity	2/1215	30/18639	0.0666666666666667	1.02271604938272	0.590955058926199	0.822098591073357
GO:0008186	ATP-dependent activity, acting on RNA	5/1215	79/18639	0.0632911392405063	0.97093295827473	0.59238371072851	0.822098591073357
GO:0016835	carbon-oxygen lyase activity	5/1215	79/18639	0.0632911392405063	0.97093295827473	0.59238371072851	0.822098591073357
GO:0001784	phosphotyrosine residue binding	3/1215	47/18639	0.0638297872340425	0.97919621749409	0.599096945616734	0.82422683703721
GO:0005504	fatty acid binding	3/1215	47/18639	0.0638297872340425	0.97919621749409	0.599096945616734	0.82422683703721
GO:0061749	forked DNA-dependent helicase activity	3/1215	47/18639	0.0638297872340425	0.97919621749409	0.599096945616734	0.82422683703721
GO:0099095	ligand-gated monoatomic anion channel activity	3/1215	47/18639	0.0638297872340425	0.97919621749409	0.599096945616734	0.82422683703721
GO:1990518	single-stranded 3'-5' DNA helicase activity	3/1215	47/18639	0.0638297872340425	0.97919621749409	0.599096945616734	0.82422683703721
GO:0003689	DNA clamp loader activity	10/1215	160/18639	0.0625	0.958796296296296	0.601041729839182	0.82422683703721
GO:0016407	acetyltransferase activity	6/1215	96/18639	0.0625	0.958796296296296	0.601808312682871	0.82422683703721
GO:0008194	UDP-glycosyltransferase activity	9/1215	145/18639	0.0620689655172414	0.952183908045977	0.609038055911841	0.82422683703721
GO:0051015	actin filament binding	13/1215	209/18639	0.062200956937799	0.954208754208754	0.610201787388015	0.82422683703721
GO:0004065	arylsulfatase activity	1/1215	14/18639	0.0714285714285714	1.0957671957672	0.610949811820034	0.82422683703721
GO:0008331	high voltage-gated calcium channel activity	1/1215	14/18639	0.0714285714285714	1.0957671957672	0.610949811820034	0.82422683703721
GO:0008474	palmitoyl-(protein) hydrolase activity	1/1215	14/18639	0.0714285714285714	1.0957671957672	0.610949811820034	0.82422683703721
GO:0008494	translation activator activity	1/1215	14/18639	0.0714285714285714	1.0957671957672	0.610949811820034	0.82422683703721
GO:0016530	metallochaperone activity	1/1215	14/18639	0.0714285714285714	1.0957671957672	0.610949811820034	0.82422683703721
GO:0019992	diacylglycerol binding	1/1215	14/18639	0.0714285714285714	1.0957671957672	0.610949811820034	0.82422683703721
GO:0032036	myosin heavy chain binding	1/1215	14/18639	0.0714285714285714	1.0957671957672	0.610949811820034	0.82422683703721
GO:0032454	histone H3K9 demethylase activity	1/1215	14/18639	0.0714285714285714	1.0957671957672	0.610949811820034	0.82422683703721
GO:0034236	protein kinase A catalytic subunit binding	1/1215	14/18639	0.0714285714285714	1.0957671957672	0.610949811820034	0.82422683703721
GO:0042043	neurexin family protein binding	1/1215	14/18639	0.0714285714285714	1.0957671957672	0.610949811820034	0.82422683703721
GO:0042813	Wnt receptor activity	1/1215	14/18639	0.0714285714285714	1.0957671957672	0.610949811820034	0.82422683703721
GO:0044548	S100 protein binding	1/1215	14/18639	0.0714285714285714	1.0957671957672	0.610949811820034	0.82422683703721
GO:0098599	palmitoyl hydrolase activity	1/1215	14/18639	0.0714285714285714	1.0957671957672	0.610949811820034	0.82422683703721
GO:0098847	sequence-specific single stranded DNA binding	1/1215	14/18639	0.0714285714285714	1.0957671957672	0.610949811820034	0.82422683703721
GO:0009378	four-way junction helicase activity	3/1215	48/18639	0.0625	0.958796296296296	0.613533325986025	0.824713275147882
GO:0036121	double-stranded DNA helicase activity	3/1215	48/18639	0.0625	0.958796296296296	0.613533325986025	0.824713275147882
GO:0043138	3'-5' DNA helicase activity	3/1215	48/18639	0.0625	0.958796296296296	0.613533325986025	0.824713275147882
GO:0001618	virus receptor activity	5/1215	81/18639	0.0617283950617284	0.946959304983996	0.614791993564333	0.825408309815564
GO:0008083	growth factor activity	10/1215	162/18639	0.0617283950617284	0.946959304983996	0.616872758878584	0.827000707981557
GO:0016298	lipase activity	8/1215	130/18639	0.0615384615384615	0.944045584045584	0.618207177934102	0.827000707981557
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	8/1215	130/18639	0.0615384615384615	0.944045584045584	0.618207177934102	0.827000707981557
GO:0160215	deacylase activity	4/1215	65/18639	0.0615384615384615	0.944045584045584	0.61947252679017	0.827698586215437
GO:0004725	protein tyrosine phosphatase activity	6/1215	98/18639	0.0612244897959184	0.939229024943311	0.622042377815473	0.829614578345045
GO:0140272	exogenous protein binding	5/1215	82/18639	0.0609756097560976	0.935411020776874	0.625720860428091	0.829614578345045
GO:0042910	xenobiotic transmembrane transporter activity	2/1215	32/18639	0.0625	0.958796296296296	0.62646880369117	0.829614578345045
GO:0043425	bHLH transcription factor binding	2/1215	32/18639	0.0625	0.958796296296296	0.62646880369117	0.829614578345045
GO:0051059	NF-kappaB binding	2/1215	32/18639	0.0625	0.958796296296296	0.62646880369117	0.829614578345045
GO:0071813	lipoprotein particle binding	2/1215	32/18639	0.0625	0.958796296296296	0.62646880369117	0.829614578345045
GO:0071814	protein-lipid complex binding	2/1215	32/18639	0.0625	0.958796296296296	0.62646880369117	0.829614578345045
GO:0005262	calcium channel activity	8/1215	131/18639	0.0610687022900763	0.936839129205541	0.626869596036103	0.829614578345045
GO:0004559	alpha-mannosidase activity	1/1215	15/18639	0.0666666666666667	1.02271604938272	0.636329461679828	0.833389555844855
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/1215	15/18639	0.0666666666666667	1.02271604938272	0.636329461679828	0.833389555844855
GO:0005041	low-density lipoprotein particle receptor activity	1/1215	15/18639	0.0666666666666667	1.02271604938272	0.636329461679828	0.833389555844855
GO:0017081	chloride channel regulator activity	1/1215	15/18639	0.0666666666666667	1.02271604938272	0.636329461679828	0.833389555844855
GO:0031005	filamin binding	1/1215	15/18639	0.0666666666666667	1.02271604938272	0.636329461679828	0.833389555844855
GO:0045504	dynein heavy chain binding	1/1215	15/18639	0.0666666666666667	1.02271604938272	0.636329461679828	0.833389555844855
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/1215	15/18639	0.0666666666666667	1.02271604938272	0.636329461679828	0.833389555844855
GO:0061578	K63-linked deubiquitinase activity	1/1215	15/18639	0.0666666666666667	1.02271604938272	0.636329461679828	0.833389555844855
GO:0008135	translation factor activity, RNA binding	5/1215	83/18639	0.0602409638554217	0.924141008478358	0.636461026476304	0.833389555844855
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	14/1215	229/18639	0.0611353711790393	0.937861879346595	0.637284002492481	0.833486597854444
GO:0140416	transcription regulator inhibitor activity	2/1215	33/18639	0.0606060606060606	0.929741863075196	0.643306993292264	0.840376389124753
GO:1990782	protein tyrosine kinase binding	7/1215	117/18639	0.0598290598290598	0.917822095599873	0.646960244355953	0.840550266394383
GO:0004860	protein kinase inhibitor activity	5/1215	84/18639	0.0595238095238095	0.913139329805996	0.647009192945098	0.840550266394383
GO:0180051	translation factor activity	5/1215	84/18639	0.0595238095238095	0.913139329805996	0.647009192945098	0.840550266394383
GO:0016741	transferase activity, transferring one-carbon groups	13/1215	215/18639	0.0604651162790698	0.927579672695952	0.650869771573003	0.840550266394383
GO:0016597	amino acid binding	3/1215	51/18639	0.0588235294117647	0.90239651416122	0.654703158323087	0.840550266394383
GO:0015020	glucuronosyltransferase activity	2/1215	34/18639	0.0588235294117647	0.90239651416122	0.659539322324482	0.840550266394383
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/1215	34/18639	0.0588235294117647	0.90239651416122	0.659539322324482	0.840550266394383
GO:0016831	carboxy-lyase activity	2/1215	34/18639	0.0588235294117647	0.90239651416122	0.659539322324482	0.840550266394383
GO:0051427	hormone receptor binding	2/1215	34/18639	0.0588235294117647	0.90239651416122	0.659539322324482	0.840550266394383
GO:0005521	lamin binding	1/1215	16/18639	0.0625	0.958796296296296	0.660054746476811	0.840550266394383
GO:0008142	oxysterol binding	1/1215	16/18639	0.0625	0.958796296296296	0.660054746476811	0.840550266394383
GO:0015378	sodium:chloride symporter activity	1/1215	16/18639	0.0625	0.958796296296296	0.660054746476811	0.840550266394383
GO:0015562	efflux transmembrane transporter activity	1/1215	16/18639	0.0625	0.958796296296296	0.660054746476811	0.840550266394383
GO:0015923	mannosidase activity	1/1215	16/18639	0.0625	0.958796296296296	0.660054746476811	0.840550266394383
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/1215	16/18639	0.0625	0.958796296296296	0.660054746476811	0.840550266394383
GO:0017070	U6 snRNA binding	1/1215	16/18639	0.0625	0.958796296296296	0.660054746476811	0.840550266394383
GO:0019841	retinol binding	1/1215	16/18639	0.0625	0.958796296296296	0.660054746476811	0.840550266394383
GO:0043023	ribosomal large subunit binding	1/1215	16/18639	0.0625	0.958796296296296	0.660054746476811	0.840550266394383
GO:0055102	lipase inhibitor activity	1/1215	16/18639	0.0625	0.958796296296296	0.660054746476811	0.840550266394383
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/1215	16/18639	0.0625	0.958796296296296	0.660054746476811	0.840550266394383
GO:0097027	ubiquitin-protein transferase activator activity	1/1215	16/18639	0.0625	0.958796296296296	0.660054746476811	0.840550266394383
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/1215	16/18639	0.0625	0.958796296296296	0.660054746476811	0.840550266394383
GO:0016209	antioxidant activity	5/1215	86/18639	0.0581395348837209	0.891903531438415	0.667518572082922	0.848351835283382
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	3/1215	52/18639	0.0576923076923077	0.885042735042735	0.667705487608484	0.848351835283382
GO:0099094	ligand-gated monoatomic cation channel activity	8/1215	136/18639	0.0588235294117647	0.90239651416122	0.668521273236576	0.848419814267171
GO:0034061	DNA polymerase activity	2/1215	35/18639	0.0571428571428571	0.876613756613757	0.675173162465146	0.85413475726623
GO:0051018	protein kinase A binding	3/1215	53/18639	0.0566037735849057	0.868343815513627	0.680346155289504	0.85413475726623
GO:0004550	nucleoside diphosphate kinase activity	1/1215	17/18639	0.0588235294117647	0.90239651416122	0.682233422470511	0.85413475726623
GO:0004659	prenyltransferase activity	1/1215	17/18639	0.0588235294117647	0.90239651416122	0.682233422470511	0.85413475726623
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/1215	17/18639	0.0588235294117647	0.90239651416122	0.682233422470511	0.85413475726623
GO:0016018	cyclosporin A binding	1/1215	17/18639	0.0588235294117647	0.90239651416122	0.682233422470511	0.85413475726623
GO:0016805	dipeptidase activity	1/1215	17/18639	0.0588235294117647	0.90239651416122	0.682233422470511	0.85413475726623
GO:0031489	myosin V binding	1/1215	17/18639	0.0588235294117647	0.90239651416122	0.682233422470511	0.85413475726623
GO:0038191	neuropilin binding	1/1215	17/18639	0.0588235294117647	0.90239651416122	0.682233422470511	0.85413475726623
GO:0045236	CXCR chemokine receptor binding	1/1215	17/18639	0.0588235294117647	0.90239651416122	0.682233422470511	0.85413475726623
GO:0070492	oligosaccharide binding	1/1215	17/18639	0.0588235294117647	0.90239651416122	0.682233422470511	0.85413475726623
GO:1990226	histone methyltransferase binding	1/1215	17/18639	0.0588235294117647	0.90239651416122	0.682233422470511	0.85413475726623
GO:0008168	methyltransferase activity	12/1215	204/18639	0.0588235294117647	0.90239651416122	0.685103294211109	0.855470017330544
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	7/1215	122/18639	0.0573770491803279	0.880206435944141	0.689755304736319	0.855470017330544
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	7/1215	122/18639	0.0573770491803279	0.880206435944141	0.689755304736319	0.855470017330544
GO:0004033	aldo-keto reductase (NADPH) activity	2/1215	36/18639	0.0555555555555556	0.852263374485597	0.690217498259505	0.855470017330544
GO:0016409	palmitoyltransferase activity	2/1215	36/18639	0.0555555555555556	0.852263374485597	0.690217498259505	0.855470017330544
GO:0055106	ubiquitin-protein transferase regulator activity	2/1215	36/18639	0.0555555555555556	0.852263374485597	0.690217498259505	0.855470017330544
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	2/1215	36/18639	0.0555555555555556	0.852263374485597	0.690217498259505	0.855470017330544
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	2/1215	36/18639	0.0555555555555556	0.852263374485597	0.690217498259505	0.855470017330544
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	2/1215	36/18639	0.0555555555555556	0.852263374485597	0.690217498259505	0.855470017330544
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	5/1215	89/18639	0.0561797752808989	0.861839367457345	0.696785202908627	0.861691034263668
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	5/1215	89/18639	0.0561797752808989	0.861839367457345	0.696785202908627	0.861691034263668
GO:0000900	mRNA regulatory element binding translation repressor activity	1/1215	18/18639	0.0555555555555556	0.852263374485597	0.702966232678777	0.862710805856532
GO:0004970	glutamate-gated receptor activity	1/1215	18/18639	0.0555555555555556	0.852263374485597	0.702966232678777	0.862710805856532
GO:0015373	monoatomic anion:sodium symporter activity	1/1215	18/18639	0.0555555555555556	0.852263374485597	0.702966232678777	0.862710805856532
GO:0016854	racemase and epimerase activity	1/1215	18/18639	0.0555555555555556	0.852263374485597	0.702966232678777	0.862710805856532
GO:0017075	syntaxin-1 binding	1/1215	18/18639	0.0555555555555556	0.852263374485597	0.702966232678777	0.862710805856532
GO:0030228	lipoprotein particle receptor activity	1/1215	18/18639	0.0555555555555556	0.852263374485597	0.702966232678777	0.862710805856532
GO:0008374	O-acyltransferase activity	3/1215	55/18639	0.0545454545454545	0.836767676767677	0.704546346520869	0.862710805856532
GO:0098632	cell-cell adhesion mediator activity	3/1215	55/18639	0.0545454545454545	0.836767676767677	0.704546346520869	0.862710805856532
GO:0030551	cyclic nucleotide binding	2/1215	37/18639	0.0540540540540541	0.829229229229229	0.70468268587241	0.862710805856532
GO:0019210	kinase inhibitor activity	5/1215	90/18639	0.0555555555555556	0.852263374485597	0.706136158252741	0.862710805856532
GO:0140793	histone H2AXY142 phosphatase activity	5/1215	90/18639	0.0555555555555556	0.852263374485597	0.706136158252741	0.862710805856532
GO:0030170	pyridoxal phosphate binding	3/1215	56/18639	0.0535714285714286	0.821825396825397	0.71610985720745	0.873936700736723
GO:0042887	amide transmembrane transporter activity	2/1215	38/18639	0.0526315789473684	0.807407407407407	0.718580236395397	0.874834183889144
GO:0048029	monosaccharide binding	4/1215	74/18639	0.0540540540540541	0.829229229229229	0.719128872476243	0.874834183889144
GO:0022821	solute:potassium antiporter activity	1/1215	19/18639	0.0526315789473684	0.807407407407407	0.722347362977649	0.874834183889144
GO:0034987	immunoglobulin receptor binding	1/1215	19/18639	0.0526315789473684	0.807407407407407	0.722347362977649	0.874834183889144
GO:0046527	glucosyltransferase activity	1/1215	19/18639	0.0526315789473684	0.807407407407407	0.722347362977649	0.874834183889144
GO:0046624	sphingolipid transporter activity	1/1215	19/18639	0.0526315789473684	0.807407407407407	0.722347362977649	0.874834183889144
GO:0097001	ceramide binding	1/1215	19/18639	0.0526315789473684	0.807407407407407	0.722347362977649	0.874834183889144
GO:0070279	vitamin B6 binding	3/1215	57/18639	0.0526315789473684	0.807407407407407	0.727319530795665	0.879898519321277
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	2/1215	39/18639	0.0512820512820513	0.78670465337132	0.731922621537085	0.883546505174377
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	2/1215	39/18639	0.0512820512820513	0.78670465337132	0.731922621537085	0.883546505174377
GO:0017116	single-stranded DNA helicase activity	3/1215	58/18639	0.0517241379310345	0.793486590038314	0.738179097456417	0.884267595181972
GO:0098631	cell adhesion mediator activity	4/1215	76/18639	0.0526315789473684	0.807407407407407	0.738435365011808	0.884267595181972
GO:0001614	purinergic nucleotide receptor activity	1/1215	20/18639	0.05	0.767037037037037	0.740464868562082	0.884267595181972
GO:0005326	neurotransmitter transmembrane transporter activity	1/1215	20/18639	0.05	0.767037037037037	0.740464868562082	0.884267595181972
GO:0016408	C-acyltransferase activity	1/1215	20/18639	0.05	0.767037037037037	0.740464868562082	0.884267595181972
GO:0016502	nucleotide receptor activity	1/1215	20/18639	0.05	0.767037037037037	0.740464868562082	0.884267595181972
GO:0030742	GTP-dependent protein binding	1/1215	20/18639	0.05	0.767037037037037	0.740464868562082	0.884267595181972
GO:0031418	L-ascorbic acid binding	1/1215	20/18639	0.05	0.767037037037037	0.740464868562082	0.884267595181972
GO:0061608	nuclear import signal receptor activity	1/1215	20/18639	0.05	0.767037037037037	0.740464868562082	0.884267595181972
GO:0140664	ATP-dependent DNA damage sensor activity	1/1215	20/18639	0.05	0.767037037037037	0.740464868562082	0.884267595181972
GO:0005085	guanyl-nucleotide exchange factor activity	13/1215	230/18639	0.0565217391304348	0.867085346215781	0.741718524524657	0.88481534597636
GO:0032451	demethylase activity	2/1215	40/18639	0.05	0.767037037037037	0.744723099703304	0.885552147403608
GO:0061791	GTPase motor activity	2/1215	40/18639	0.05	0.767037037037037	0.744723099703304	0.885552147403608
GO:1990606	membrane scission GTPase motor activity	2/1215	40/18639	0.05	0.767037037037037	0.744723099703304	0.885552147403608
GO:0001530	lipopolysaccharide binding	2/1215	41/18639	0.0487804878048781	0.7483288166215	0.756995560637811	0.892050152281824
GO:0015175	neutral L-amino acid transmembrane transporter activity	2/1215	41/18639	0.0487804878048781	0.7483288166215	0.756995560637811	0.892050152281824
GO:0140828	metal cation:monoatomic cation antiporter activity	2/1215	41/18639	0.0487804878048781	0.7483288166215	0.756995560637811	0.892050152281824
GO:0001846	opsonin binding	1/1215	21/18639	0.0476190476190476	0.730511463844797	0.757401072692115	0.892050152281824
GO:0005123	death receptor binding	1/1215	21/18639	0.0476190476190476	0.730511463844797	0.757401072692115	0.892050152281824
GO:0005248	voltage-gated sodium channel activity	1/1215	21/18639	0.0476190476190476	0.730511463844797	0.757401072692115	0.892050152281824
GO:0019200	carbohydrate kinase activity	1/1215	21/18639	0.0476190476190476	0.730511463844797	0.757401072692115	0.892050152281824
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/1215	21/18639	0.0476190476190476	0.730511463844797	0.757401072692115	0.892050152281824
GO:1904047	S-adenosyl-L-methionine binding	1/1215	21/18639	0.0476190476190476	0.730511463844797	0.757401072692115	0.892050152281824
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3/1215	60/18639	0.05	0.767037037037037	0.758865635997357	0.892830288440865
GO:0016829	lyase activity	11/1215	200/18639	0.055	0.843740740740741	0.761605407414646	0.895107516845302
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	7/1215	132/18639	0.053030303030303	0.813524130190797	0.764797182845352	0.897910616568436
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	3/1215	61/18639	0.0491803278688525	0.754462659380692	0.768702692752731	0.898296376999708
GO:0004520	DNA endonuclease activity	2/1215	42/18639	0.0476190476190476	0.730511463844797	0.768754386946019	0.898296376999708
GO:0008307	structural constituent of muscle	2/1215	42/18639	0.0476190476190476	0.730511463844797	0.768754386946019	0.898296376999708
GO:0016859	cis-trans isomerase activity	2/1215	42/18639	0.0476190476190476	0.730511463844797	0.768754386946019	0.898296376999708
GO:0019842	vitamin binding	8/1215	150/18639	0.0533333333333333	0.818172839506173	0.76916122846426	0.898296376999708
GO:0005243	gap junction channel activity	1/1215	22/18639	0.0454545454545455	0.697306397306397	0.773232939524163	0.899277180449732
GO:0008093	cytoskeletal anchor activity	1/1215	22/18639	0.0454545454545455	0.697306397306397	0.773232939524163	0.899277180449732
GO:0015377	chloride:monoatomic cation symporter activity	1/1215	22/18639	0.0454545454545455	0.697306397306397	0.773232939524163	0.899277180449732
GO:0061133	endopeptidase activator activity	1/1215	22/18639	0.0454545454545455	0.697306397306397	0.773232939524163	0.899277180449732
GO:0015101	organic cation transmembrane transporter activity	4/1215	81/18639	0.0493827160493827	0.757567443987197	0.782271689070222	0.908839655464674
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/1215	23/18639	0.0434782608695652	0.666988727858293	0.788032422710398	0.911725661618164
GO:0004602	glutathione peroxidase activity	1/1215	23/18639	0.0434782608695652	0.666988727858293	0.788032422710398	0.911725661618164
GO:0005212	structural constituent of eye lens	1/1215	23/18639	0.0434782608695652	0.666988727858293	0.788032422710398	0.911725661618164
GO:0099186	structural constituent of postsynapse	1/1215	23/18639	0.0434782608695652	0.666988727858293	0.788032422710398	0.911725661618164
GO:0016790	thiolester hydrolase activity	2/1215	44/18639	0.0454545454545455	0.697306397306397	0.790790405561069	0.913966481193635
GO:0005254	chloride channel activity	4/1215	83/18639	0.0481927710843374	0.739312806782686	0.798089248602597	0.917480096139285
GO:0004622	lysophospholipase activity	1/1215	24/18639	0.0416666666666667	0.639197530864198	0.801866791339903	0.917480096139285
GO:0004806	triacylglycerol lipase activity	1/1215	24/18639	0.0416666666666667	0.639197530864198	0.801866791339903	0.917480096139285
GO:0019957	C-C chemokine binding	1/1215	24/18639	0.0416666666666667	0.639197530864198	0.801866791339903	0.917480096139285
GO:0048027	mRNA 5'-UTR binding	1/1215	24/18639	0.0416666666666667	0.639197530864198	0.801866791339903	0.917480096139285
GO:0070300	phosphatidic acid binding	1/1215	24/18639	0.0416666666666667	0.639197530864198	0.801866791339903	0.917480096139285
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/1215	24/18639	0.0416666666666667	0.639197530864198	0.801866791339903	0.917480096139285
GO:0070840	dynein complex binding	1/1215	24/18639	0.0416666666666667	0.639197530864198	0.801866791339903	0.917480096139285
GO:0140612	DNA damage sensor activity	1/1215	24/18639	0.0416666666666667	0.639197530864198	0.801866791339903	0.917480096139285
GO:0032182	ubiquitin-like protein binding	6/1215	120/18639	0.05	0.767037037037037	0.802073794738117	0.917480096139285
GO:0019843	rRNA binding	3/1215	65/18639	0.0461538461538462	0.708034188034188	0.804812076134236	0.918815819973207
GO:0003823	antigen binding	9/1215	174/18639	0.0517241379310345	0.793486590038314	0.807290629735009	0.918815819973207
GO:0004540	RNA nuclease activity	6/1215	121/18639	0.0495867768595041	0.760697887970615	0.808366136966535	0.918815819973207
GO:0004180	carboxypeptidase activity	2/1215	46/18639	0.0434782608695652	0.666988727858293	0.810951732801021	0.918815819973207
GO:0030276	clathrin binding	2/1215	46/18639	0.0434782608695652	0.666988727858293	0.810951732801021	0.918815819973207
GO:0008528	G protein-coupled peptide receptor activity	6/1215	122/18639	0.0491803278688525	0.754462659380692	0.814501180012926	0.918815819973207
GO:0001848	complement binding	1/1215	25/18639	0.04	0.61362962962963	0.814798934693222	0.918815819973207
GO:0005251	delayed rectifier potassium channel activity	1/1215	25/18639	0.04	0.61362962962963	0.814798934693222	0.918815819973207
GO:0015271	outward rectifier potassium channel activity	1/1215	25/18639	0.04	0.61362962962963	0.814798934693222	0.918815819973207
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/1215	25/18639	0.04	0.61362962962963	0.814798934693222	0.918815819973207
GO:0015645	fatty acid ligase activity	1/1215	25/18639	0.04	0.61362962962963	0.814798934693222	0.918815819973207
GO:0017056	structural constituent of nuclear pore	1/1215	25/18639	0.04	0.61362962962963	0.814798934693222	0.918815819973207
GO:0047617	fatty acyl-CoA hydrolase activity	1/1215	25/18639	0.04	0.61362962962963	0.814798934693222	0.918815819973207
GO:0120515	fatty acid-CoA ligase activity	1/1215	25/18639	0.04	0.61362962962963	0.814798934693222	0.918815819973207
GO:0030246	carbohydrate binding	15/1215	280/18639	0.0535714285714286	0.821825396825397	0.818768116229861	0.922291948229211
GO:0050660	flavin adenine dinucleotide binding	4/1215	86/18639	0.0465116279069767	0.713522825150732	0.820060741638807	0.922291948229211
GO:0043495	protein-membrane adaptor activity	2/1215	47/18639	0.0425531914893617	0.652797478329393	0.820367501120322	0.922291948229211
GO:0008066	glutamate receptor activity	1/1215	26/18639	0.0384615384615385	0.59002849002849	0.826887647186385	0.924927859985345
GO:0016289	acyl-CoA hydrolase activity	1/1215	26/18639	0.0384615384615385	0.59002849002849	0.826887647186385	0.924927859985345
GO:0030507	spectrin binding	1/1215	26/18639	0.0384615384615385	0.59002849002849	0.826887647186385	0.924927859985345
GO:0034237	protein kinase A regulatory subunit binding	1/1215	26/18639	0.0384615384615385	0.59002849002849	0.826887647186385	0.924927859985345
GO:0050681	nuclear androgen receptor binding	1/1215	26/18639	0.0384615384615385	0.59002849002849	0.826887647186385	0.924927859985345
GO:0003777	microtubule motor activity	3/1215	68/18639	0.0441176470588235	0.676797385620915	0.828676476881811	0.924927859985345
GO:0030145	manganese ion binding	3/1215	68/18639	0.0441176470588235	0.676797385620915	0.828676476881811	0.924927859985345
GO:0016879	ligase activity, forming carbon-nitrogen bonds	2/1215	48/18639	0.0416666666666667	0.639197530864198	0.829360291343553	0.924927859985345
GO:0060590	ATPase regulator activity	2/1215	49/18639	0.0408163265306122	0.62615268329554	0.837945184294462	0.931971155746866
GO:0001671	ATPase activator activity	1/1215	27/18639	0.037037037037037	0.568175582990398	0.838187894791206	0.931971155746866
GO:0016405	CoA-ligase activity	1/1215	27/18639	0.037037037037037	0.568175582990398	0.838187894791206	0.931971155746866
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	9/1215	181/18639	0.0497237569060773	0.76279926335175	0.841498485319499	0.934718377405791
GO:0016782	transferase activity, transferring sulphur-containing groups	3/1215	70/18639	0.0428571428571429	0.657460317460317	0.843159071895422	0.935306865725123
GO:0015605	organophosphate ester transmembrane transporter activity	2/1215	50/18639	0.04	0.61362962962963	0.846137093649389	0.935306865725123
GO:0032813	tumor necrosis factor receptor superfamily binding	2/1215	50/18639	0.04	0.61362962962963	0.846137093649389	0.935306865725123
GO:0048020	CCR chemokine receptor binding	2/1215	50/18639	0.04	0.61362962962963	0.846137093649389	0.935306865725123
GO:0001653	peptide receptor activity	6/1215	128/18639	0.046875	0.719097222222222	0.848115227497009	0.935306865725123
GO:0046625	sphingolipid binding	1/1215	28/18639	0.0357142857142857	0.547883597883598	0.848751064135107	0.935306865725123
GO:0046966	nuclear thyroid hormone receptor binding	1/1215	28/18639	0.0357142857142857	0.547883597883598	0.848751064135107	0.935306865725123
GO:0141052	histone H3 demethylase activity	1/1215	28/18639	0.0357142857142857	0.547883597883598	0.848751064135107	0.935306865725123
GO:0015103	inorganic anion transmembrane transporter activity	8/1215	165/18639	0.0484848484848485	0.743793490460157	0.850306817691106	0.936094449149556
GO:0016830	carbon-carbon lyase activity	2/1215	51/18639	0.0392156862745098	0.60159767610748	0.853950723662708	0.939177031063828
GO:0004181	metallocarboxypeptidase activity	1/1215	29/18639	0.0344827586206897	0.528991060025543	0.858625195405638	0.942455465962993
GO:0051861	glycolipid binding	1/1215	29/18639	0.0344827586206897	0.528991060025543	0.858625195405638	0.942455465962993
GO:0005200	structural constituent of cytoskeleton	5/1215	112/18639	0.0446428571428571	0.684854497354497	0.862276189065404	0.945270936224967
GO:0004521	RNA endonuclease activity	3/1215	73/18639	0.0410958904109589	0.630441400304414	0.862888833067894	0.945270936224967
GO:0032452	histone demethylase activity	1/1215	30/18639	0.0333333333333333	0.511358024691358	0.867855200111825	0.94633663300267
GO:0033612	receptor serine/threonine kinase binding	1/1215	30/18639	0.0333333333333333	0.511358024691358	0.867855200111825	0.94633663300267
GO:0005544	calcium-dependent phospholipid binding	2/1215	53/18639	0.0377358490566038	0.578895877009085	0.868500704783911	0.94633663300267
GO:0008146	sulfotransferase activity	2/1215	53/18639	0.0377358490566038	0.578895877009085	0.868500704783911	0.94633663300267
GO:1901505	carbohydrate derivative transmembrane transporter activity	2/1215	53/18639	0.0377358490566038	0.578895877009085	0.868500704783911	0.94633663300267
GO:0003678	DNA helicase activity	3/1215	74/18639	0.0405405405405405	0.621921921921922	0.868963197599936	0.94633663300267
GO:0005164	tumor necrosis factor receptor binding	1/1215	31/18639	0.032258064516129	0.494862604540024	0.876483064686178	0.948954913419957
GO:0005452	solute:inorganic anion antiporter activity	1/1215	31/18639	0.032258064516129	0.494862604540024	0.876483064686178	0.948954913419957
GO:0016878	acid-thiol ligase activity	1/1215	31/18639	0.032258064516129	0.494862604540024	0.876483064686178	0.948954913419957
GO:0047499	calcium-independent phospholipase A2 activity	1/1215	31/18639	0.032258064516129	0.494862604540024	0.876483064686178	0.948954913419957
GO:0072349	modified amino acid transmembrane transporter activity	1/1215	31/18639	0.032258064516129	0.494862604540024	0.876483064686178	0.948954913419957
GO:0140457	protein demethylase activity	1/1215	31/18639	0.032258064516129	0.494862604540024	0.876483064686178	0.948954913419957
GO:0015297	antiporter activity	6/1215	135/18639	0.0444444444444444	0.681810699588477	0.880871611083115	0.951209632331452
GO:0004518	nuclease activity	10/1215	209/18639	0.0478468899521531	0.734006734006734	0.881232130761243	0.951209632331452
GO:0005244	voltage-gated monoatomic ion channel activity	8/1215	173/18639	0.046242774566474	0.709398415756797	0.883229379862187	0.951209632331452
GO:0030515	snoRNA binding	1/1215	32/18639	0.03125	0.479398148148148	0.884548040847307	0.951209632331452
GO:0031369	translation initiation factor binding	1/1215	32/18639	0.03125	0.479398148148148	0.884548040847307	0.951209632331452
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/1215	32/18639	0.03125	0.479398148148148	0.884548040847307	0.951209632331452
GO:0047498	calcium-dependent phospholipase A2 activity	1/1215	32/18639	0.03125	0.479398148148148	0.884548040847307	0.951209632331452
GO:0005249	voltage-gated potassium channel activity	4/1215	98/18639	0.0408163265306122	0.62615268329554	0.889046060797289	0.95512380855925
GO:0022832	voltage-gated channel activity	8/1215	175/18639	0.0457142857142857	0.701291005291005	0.890452927489926	0.955488268827108
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/1215	33/18639	0.0303030303030303	0.464870931537598	0.892086823583402	0.955488268827108
GO:0019239	deaminase activity	1/1215	33/18639	0.0303030303030303	0.464870931537598	0.892086823583402	0.955488268827108
GO:0004601	peroxidase activity	2/1215	57/18639	0.0350877192982456	0.538271604938272	0.893677706962281	0.955488268827108
GO:0015932	nucleobase-containing compound transmembrane transporter activity	2/1215	57/18639	0.0350877192982456	0.538271604938272	0.893677706962281	0.955488268827108
GO:0043130	ubiquitin binding	4/1215	100/18639	0.04	0.61362962962963	0.89796553819873	0.95915128984183
GO:0090482	vitamin transmembrane transporter activity	1/1215	34/18639	0.0294117647058824	0.45119825708061	0.899133717560946	0.959478262363693
GO:0000049	tRNA binding	3/1215	80/18639	0.0375	0.575277777777778	0.900646389715647	0.960171869495705
GO:0015108	chloride transmembrane transporter activity	5/1215	121/18639	0.0413223140495868	0.633914906642179	0.902257646993857	0.960969149381974
GO:0015079	potassium ion transmembrane transporter activity	7/1215	160/18639	0.04375	0.671157407407407	0.903422007137345	0.960979258615009
GO:0030971	receptor tyrosine kinase binding	3/1215	81/18639	0.037037037037037	0.568175582990398	0.905199262817395	0.960979258615009
GO:0004623	phospholipase A2 activity	1/1215	35/18639	0.0285714285714286	0.438306878306878	0.905720792710822	0.960979258615009
GO:0016229	steroid dehydrogenase activity	1/1215	35/18639	0.0285714285714286	0.438306878306878	0.905720792710822	0.960979258615009
GO:0005253	monoatomic anion channel activity	4/1215	103/18639	0.0388349514563107	0.595756921970514	0.91016041643465	0.963836891786037
GO:0022843	voltage-gated monoatomic cation channel activity	6/1215	143/18639	0.041958041958042	0.643667443667444	0.910811548529474	0.963836891786037
GO:0004190	aspartic-type endopeptidase activity	1/1215	36/18639	0.0277777777777778	0.426131687242798	0.911878029695145	0.963836891786037
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/1215	36/18639	0.0277777777777778	0.426131687242798	0.911878029695145	0.963836891786037
GO:0005267	potassium channel activity	5/1215	124/18639	0.0403225806451613	0.61857825567503	0.913133020483094	0.964247677227404
GO:0022829	wide pore channel activity	1/1215	37/18639	0.027027027027027	0.414614614614615	0.917633455912443	0.96624979794754
GO:0030280	structural constituent of skin epidermis	1/1215	37/18639	0.027027027027027	0.414614614614615	0.917633455912443	0.96624979794754
GO:0070001	aspartic-type peptidase activity	1/1215	37/18639	0.027027027027027	0.414614614614615	0.917633455912443	0.96624979794754
GO:0015179	L-amino acid transmembrane transporter activity	2/1215	62/18639	0.032258064516129	0.494862604540024	0.918846269871014	0.966612380308543
GO:0000146	microfilament motor activity	1/1215	38/18639	0.0263157894736842	0.403703703703704	0.923013272656147	0.968174105729352
GO:0005109	frizzled binding	1/1215	38/18639	0.0263157894736842	0.403703703703704	0.923013272656147	0.968174105729352
GO:1901682	sulfur compound transmembrane transporter activity	2/1215	63/18639	0.0317460317460317	0.487007642563198	0.923156223734402	0.968174105729352
GO:0015276	ligand-gated monoatomic ion channel activity	8/1215	186/18639	0.043010752688172	0.659816806053365	0.923810332690541	0.968174105729352
GO:0004536	DNA nuclease activity	2/1215	64/18639	0.03125	0.479398148148148	0.927249716658493	0.970864472851272
GO:0022834	ligand-gated channel activity	8/1215	188/18639	0.0425531914893617	0.652797478329393	0.928826449448492	0.971601351725725
GO:0140662	ATP-dependent protein folding chaperone	1/1215	40/18639	0.025	0.383518518518519	0.932742457957747	0.974781554654434
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/1215	41/18639	0.024390243902439	0.37416440831075	0.937136130390745	0.978454515126547
GO:0003774	cytoskeletal motor activity	6/1215	153/18639	0.0392156862745098	0.60159767610748	0.938889265196545	0.97936621571111
GO:0140223	general transcription initiation factor activity	2/1215	68/18639	0.0294117647058824	0.45119825708061	0.941651159491051	0.981327472390955
GO:0016758	hexosyltransferase activity	8/1215	197/18639	0.0406091370558376	0.622974243278812	0.948003669764784	0.987023465339761
GO:0005126	cytokine receptor binding	12/1215	275/18639	0.0436363636363636	0.669414141414141	0.950200068169127	0.98838567838527
GO:0008009	chemokine activity	1/1215	45/18639	0.0222222222222222	0.340905349794239	0.952023864386059	0.98935813357767
GO:0042379	chemokine receptor binding	2/1215	72/18639	0.0277777777777778	0.426131687242798	0.953314950641597	0.98973943179898
GO:0004896	cytokine receptor activity	3/1215	96/18639	0.03125	0.479398148148148	0.954169281509708	0.98973943179898
GO:0020037	heme binding	5/1215	142/18639	0.0352112676056338	0.540166927490871	0.95862575602459	0.99343618850593
GO:0008188	neuropeptide receptor activity	1/1215	48/18639	0.0208333333333333	0.319598765432099	0.960827955964925	0.993867578986024
GO:0038187	pattern recognition receptor activity	1/1215	48/18639	0.0208333333333333	0.319598765432099	0.960827955964925	0.993867578986024
GO:0005261	monoatomic cation channel activity	15/1215	341/18639	0.0439882697947214	0.674812642554578	0.962843429991845	0.995027611495751
GO:0015171	amino acid transmembrane transporter activity	3/1215	102/18639	0.0294117647058824	0.45119825708061	0.966096301490233	0.996731556320427
GO:0005272	sodium channel activity	1/1215	51/18639	0.0196078431372549	0.30079883805374	0.968017492946923	0.996731556320427
GO:0004519	endonuclease activity	4/1215	127/18639	0.031496062992126	0.483172936716244	0.96942126561408	0.996731556320427
GO:0008509	monoatomic anion transmembrane transporter activity	5/1215	149/18639	0.0335570469798658	0.514789957742978	0.969427585418891	0.996731556320427
GO:0140098	catalytic activity, acting on RNA	17/1215	387/18639	0.0439276485788114	0.673882668197914	0.971114094782324	0.996731556320427
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/1215	53/18639	0.0188679245283019	0.289447938504542	0.972062008432572	0.996731556320427
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/1215	53/18639	0.0188679245283019	0.289447938504542	0.972062008432572	0.996731556320427
GO:0004497	monooxygenase activity	3/1215	106/18639	0.0283018867924528	0.434171907756813	0.972350049343704	0.996731556320427
GO:0046906	tetrapyrrole binding	5/1215	152/18639	0.0328947368421053	0.50462962962963	0.973203971915775	0.996731556320427
GO:0016798	hydrolase activity, acting on glycosyl bonds	4/1215	130/18639	0.0307692307692308	0.472022792022792	0.973447620593265	0.996731556320427
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/1215	56/18639	0.0178571428571429	0.273941798941799	0.977190963467902	0.999644799944646
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	2/1215	91/18639	0.021978021978022	0.337159137159137	0.984249632196109	0.999999995355621
GO:0022824	transmitter-gated monoatomic ion channel activity	1/1215	63/18639	0.0158730158730159	0.243503821281599	0.985792734902368	0.999999995355621
GO:0022835	transmitter-gated channel activity	1/1215	63/18639	0.0158730158730159	0.243503821281599	0.985792734902368	0.999999995355621
GO:0098960	postsynaptic neurotransmitter receptor activity	1/1215	69/18639	0.0144927536231884	0.222329575952764	0.990532808882948	0.999999995355621
GO:0046873	metal ion transmembrane transporter activity	18/1215	450/18639	0.04	0.61362962962963	0.992429663537025	0.999999995355621
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/1215	73/18639	0.0136986301369863	0.210147133434805	0.99277792196778	0.999999995355621
GO:0022836	gated channel activity	11/1215	318/18639	0.0345911949685535	0.530654553924994	0.994387339123743	0.999999995355621
GO:0005125	cytokine activity	7/1215	234/18639	0.0299145299145299	0.458911047799937	0.994905877648541	0.999999995355621
GO:0015081	sodium ion transmembrane transporter activity	4/1215	164/18639	0.024390243902439	0.37416440831075	0.995042019491916	0.999999995355621
GO:0015370	solute:sodium symporter activity	1/1215	79/18639	0.0126582278481013	0.194186591654946	0.995188565440552	0.999999995355621
GO:0140101	catalytic activity, acting on a tRNA	3/1215	139/18639	0.0215827338129496	0.331095123900879	0.9952201806356	0.999999995355621
GO:0015291	secondary active transmembrane transporter activity	9/1215	287/18639	0.0313588850174216	0.481068524970964	0.996490290129386	0.999999995355621
GO:0015293	symporter activity	3/1215	146/18639	0.0205479452054795	0.315220700152207	0.996750939293634	0.999999995355621
GO:0008514	organic anion transmembrane transporter activity	8/1215	269/18639	0.0297397769516729	0.45623020790307	0.997060493450979	0.999999995355621
GO:0005216	monoatomic ion channel activity	16/1215	448/18639	0.0357142857142857	0.547883597883598	0.997915023951345	0.999999995355621
GO:0052689	carboxylic ester hydrolase activity	1/1215	92/18639	0.0108695652173913	0.166747181964573	0.998005201683345	0.999999995355621
GO:0140375	immune receptor activity	3/1215	156/18639	0.0192307692307692	0.295014245014245	0.998140795149984	0.999999995355621
GO:0030594	neurotransmitter receptor activity	1/1215	97/18639	0.0103092783505155	0.158151966399389	0.998578464802465	0.999999995355621
GO:0005179	hormone activity	2/1215	132/18639	0.0151515151515152	0.232435465768799	0.998640534546154	0.999999995355621
GO:0016874	ligase activity	3/1215	167/18639	0.0179640718562874	0.275582168995343	0.999002136243362	0.999999995355621
GO:0015294	solute:monoatomic cation symporter activity	1/1215	116/18639	0.00862068965517241	0.132247765006386	0.999608036391857	0.999999995355621
GO:0046943	carboxylic acid transmembrane transporter activity	3/1215	188/18639	0.0159574468085106	0.244799054373522	0.999702076555608	0.999999995355621
GO:0005342	organic acid transmembrane transporter activity	3/1215	189/18639	0.0158730158730159	0.243503821281599	0.999718912778301	0.999999995355621
GO:0045182	translation regulator activity	3/1215	356/18639	0.00842696629213483	0.129275905118602	0.999999989683868	0.999999995355621
GO:0030371	translation repressor activity	2/1215	329/18639	0.0060790273556231	0.0932567826184847	0.999999995355621	0.999999995355621