ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	90/1458	175/18639	0.514285714285714	6.57460317460317	8.00795272226343e-53	8.79273208904525e-50
GO:0015078	proton transmembrane transporter activity	50/1458	185/18639	0.27027027027027	3.45512178845512	3.15716634932343e-15	1.73328432577857e-12
GO:0009055	electron transfer activity	36/1458	116/18639	0.310344827586207	3.96743295019157	2.55428435640573e-13	8.40701474220979e-11
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	27/1458	68/18639	0.397058823529412	5.07598039215686	3.0626647512604e-13	8.40701474220979e-11
GO:0044389	ubiquitin-like protein ligase binding	64/1458	322/18639	0.198757763975155	2.54090943946016	2.87039315479017e-12	6.30338336791921e-10
GO:0022853	active monoatomic ion transmembrane transporter activity	34/1458	118/18639	0.288135593220339	3.68351119481063	1.20891123985939e-11	2.20730453371378e-09
GO:0031625	ubiquitin protein ligase binding	60/1458	302/18639	0.198675496688742	2.53985773853324	1.40720689763173e-11	2.20730453371378e-09
GO:0023023	MHC protein complex binding	18/1458	37/18639	0.486486486486487	6.21921921921922	4.55373788424986e-11	6.25000524613293e-09
GO:0003697	single-stranded DNA binding	32/1458	121/18639	0.264462809917355	3.38087950209162	5.48960485811022e-10	6.57146631202502e-08
GO:0031386	protein tag activity	11/1458	15/18639	0.733333333333333	9.37489711934156	6.58343619601778e-10	6.57146631202502e-08
GO:0141047	molecular tag activity	11/1458	15/18639	0.733333333333333	9.37489711934156	6.58343619601778e-10	6.57146631202502e-08
GO:0003954	NADH dehydrogenase activity	18/1458	44/18639	0.409090909090909	5.22979797979798	1.56096847831768e-09	1.42828615766068e-07
GO:0023026	MHC class II protein complex binding	14/1458	27/18639	0.518518518518518	6.62871513488797	2.29432845024899e-09	1.89166549084649e-07
GO:0042605	peptide antigen binding	18/1458	45/18639	0.4	5.11358024691358	2.41195964224506e-09	1.89166549084649e-07
GO:0008137	NADH dehydrogenase (ubiquinone) activity	17/1458	41/18639	0.414634146341463	5.30066245106895	3.4737904772727e-09	2.54281462936362e-07
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	20/1458	58/18639	0.344827586206897	4.40825883354619	6.65994663694263e-09	4.57038837960188e-07
GO:0019843	rRNA binding	21/1458	65/18639	0.323076923076923	4.13019943019943	1.06489217468791e-08	6.87795063416071e-07
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	11/1458	18/18639	0.611111111111111	7.81241426611797	1.2305023468846e-08	7.50606431599603e-07
GO:0015399	primary active transmembrane transporter activity	35/1458	166/18639	0.210843373493976	2.69541127472854	5.30897534345339e-08	3.06802890900622e-06
GO:0042277	peptide binding	45/1458	249/18639	0.180722891566265	2.31035252119589	9.78486738228242e-08	5.37189219287305e-06
GO:0042608	T cell receptor binding	8/1458	11/18639	0.727272727272727	9.29741863075196	1.83292266348444e-07	9.58356706907578e-06
GO:0045296	cadherin binding	53/1458	334/18639	0.158682634730539	2.02859096621572	5.88179216923709e-07	2.93554900082833e-05
GO:0016651	oxidoreductase activity, acting on NAD(P)H	22/1458	88/18639	0.25	3.19598765432099	7.64761061812861e-07	3.6509028081327e-05
GO:0015252	proton channel activity	11/1458	27/18639	0.407407407407407	5.20827617741198	2.60324775096155e-06	0.000119098584606491
GO:0140375	immune receptor activity	30/1458	156/18639	0.192307692307692	2.45845204178538	3.5189467594301e-06	0.00015455214167417
GO:0070990	snRNP binding	7/1458	11/18639	0.636363636363636	8.13524130190797	4.40246360887778e-06	0.000185919424713377
GO:0055105	ubiquitin-protein transferase inhibitor activity	8/1458	15/18639	0.533333333333333	6.81810699588477	5.37274411319569e-06	0.000218491593936625
GO:0051082	unfolded protein binding	25/1458	121/18639	0.206611570247934	2.64131211100908	6.02439733508205e-06	0.000236242438354289
GO:0042287	MHC protein binding	13/1458	41/18639	0.317073170731707	4.05344775669979	8.58206232450316e-06	0.000324934635596706
GO:0016504	peptidase activator activity	15/1458	57/18639	0.263157894736842	3.3641975308642	2.22721479240743e-05	0.000815160614021121
GO:0032395	MHC class II receptor activity	6/1458	10/18639	0.6	7.67037037037037	3.61648567377523e-05	0.00128093589348555
GO:0051087	protein-folding chaperone binding	25/1458	134/18639	0.186567164179104	2.38506541367238	3.79363724332774e-05	0.00130169177911683
GO:0016860	intramolecular oxidoreductase activity	14/1458	53/18639	0.264150943396226	3.37689261588633	3.97054095418821e-05	0.00132110726293899
GO:0048027	mRNA 5'-UTR binding	9/1458	24/18639	0.375	4.79398148148148	4.74648303650186e-05	0.0015328348159056
GO:0055106	ubiquitin-protein transferase regulator activity	11/1458	36/18639	0.305555555555556	3.90620713305899	6.21692602723752e-05	0.00195033850797337
GO:0042288	MHC class I protein binding	8/1458	20/18639	0.4	5.11358024691358	7.37210768310981e-05	0.00224849284334849
GO:0004857	enzyme inhibitor activity	55/1458	416/18639	0.132211538461538	1.69018577872745	8.62043553587777e-05	0.00255817249145778
GO:0003924	GTPase activity	46/1458	331/18639	0.138972809667674	1.77662153593674	9.88984897787941e-05	0.00285764583623989
GO:0003688	DNA replication origin binding	7/1458	16/18639	0.4375	5.59297839506173	0.000107511452168607	0.00302686088413156
GO:0043021	ribonucleoprotein complex binding	29/1458	177/18639	0.163841807909605	2.09454558136291	0.000112887787778792	0.00309876977452784
GO:0016853	isomerase activity	29/1458	180/18639	0.161111111111111	2.05963648834019	0.000152689179704402	0.00402140326005447
GO:0003678	DNA helicase activity	16/1458	74/18639	0.216216216216216	2.7640974307641	0.000157486648617798	0.00402140326005447
GO:0003684	damaged DNA binding	16/1458	74/18639	0.216216216216216	2.7640974307641	0.000157486648617798	0.00402140326005447
GO:0061134	peptidase regulator activity	34/1458	226/18639	0.150442477876106	1.92324920790998	0.000171721487150316	0.0042852316566147
GO:0015036	disulfide oxidoreductase activity	11/1458	40/18639	0.275	3.51558641975309	0.00017883808122021	0.00436364918177313
GO:0044183	protein folding chaperone	16/1458	75/18639	0.213333333333333	2.72724279835391	0.000185858235513437	0.00443635527377725
GO:0015035	protein-disulfide reductase activity	10/1458	34/18639	0.294117647058824	3.75998547567175	0.000190827368651841	0.00445805214424938
GO:0008135	translation factor activity, RNA binding	17/1458	83/18639	0.204819277108434	2.61839952402201	0.000199864001750545	0.00457188904004372
GO:0180051	translation factor activity	17/1458	84/18639	0.202380952380952	2.58722810111699	0.000232589152421329	0.0052118957011963
GO:0019207	kinase regulator activity	40/1458	287/18639	0.139372822299652	1.78173527767024	0.000257037136068746	0.00564453550806966
GO:0017116	single-stranded DNA helicase activity	13/1458	58/18639	0.224137931034483	2.86536824180502	0.000439947623565415	0.00947181354264364
GO:0003743	translation initiation factor activity	12/1458	51/18639	0.235294117647059	3.0079883805374	0.000451727937440578	0.0095384091405722
GO:0031072	heat shock protein binding	22/1458	131/18639	0.16793893129771	2.14692300442937	0.000510828611951108	0.0105828267155154
GO:0004715	non-membrane spanning protein tyrosine kinase activity	11/1458	45/18639	0.244444444444444	3.12496570644719	0.000546495479702689	0.0110068460675312
GO:0016505	peptidase activator activity involved in apoptotic process	7/1458	20/18639	0.35	4.47438271604938	0.000551344748373604	0.0110068460675312
GO:0004129	cytochrome-c oxidase activity	6/1458	15/18639	0.4	5.11358024691358	0.000612006958807861	0.0117891866801935
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	6/1458	15/18639	0.4	5.11358024691358	0.000612006958807861	0.0117891866801935
GO:0140311	protein sequestering activity	9/1458	33/18639	0.272727272727273	3.48653198653199	0.000736114397322056	0.0138945732511756
GO:0003779	actin binding	54/1458	443/18639	0.121896162528217	1.55831452219714	0.000753772828182046	0.0138945732511756
GO:0070182	DNA polymerase binding	7/1458	21/18639	0.333333333333333	4.26131687242798	0.00077154570419942	0.0138945732511756
GO:0003925	G protein activity	12/1458	54/18639	0.222222222222222	2.84087791495199	0.000784575174474398	0.0138945732511756
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	12/1458	54/18639	0.222222222222222	2.84087791495199	0.000784575174474398	0.0138945732511756
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	10/1458	40/18639	0.25	3.19598765432099	0.000801278350231415	0.0139651369611761
GO:0051015	actin filament binding	30/1458	209/18639	0.143540669856459	1.83501683501683	0.000888914618582323	0.0149902280678355
GO:1990948	ubiquitin ligase inhibitor activity	5/1458	11/18639	0.454545454545455	5.81088664421998	0.000900303060659922	0.0149902280678355
GO:0016675	oxidoreductase activity, acting on a heme group of donors	6/1458	16/18639	0.375	4.79398148148148	0.000914704262791417	0.0149902280678355
GO:0017070	U6 snRNA binding	6/1458	16/18639	0.375	4.79398148148148	0.000914704262791417	0.0149902280678355
GO:0140313	molecular sequestering activity	12/1458	55/18639	0.218181818181818	2.78922558922559	0.000933177015787595	0.0150680641666879
GO:0005092	GDP-dissociation inhibitor activity	6/1458	17/18639	0.352941176470588	4.5119825708061	0.00132066290878256	0.0207155410549037
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	6/1458	17/18639	0.352941176470588	4.5119825708061	0.00132066290878256	0.0207155410549037
GO:0043539	protein serine/threonine kinase activator activity	14/1458	73/18639	0.191780821917808	2.45171655673939	0.00139982508085809	0.0216479991377772
GO:0019887	protein kinase regulator activity	34/1458	255/18639	0.133333333333333	1.70452674897119	0.00155979158697239	0.0237868217013289
GO:0016887	ATP hydrolysis activity	50/1458	417/18639	0.119904076738609	1.5328477958374	0.00165220077546753	0.0248509102940185
GO:0045309	protein phosphorylated amino acid binding	12/1458	59/18639	0.203389830508475	2.60012554927809	0.00178133902444119	0.0262954766125713
GO:0001540	amyloid-beta binding	15/1458	83/18639	0.180722891566265	2.31035252119589	0.00179613911288055	0.0262954766125713
GO:0002020	protease binding	21/1458	136/18639	0.154411764705882	1.97399237472767	0.00202551688705316	0.0288833447010958
GO:0044325	transmembrane transporter binding	21/1458	136/18639	0.154411764705882	1.97399237472767	0.00202551688705316	0.0288833447010958
GO:0043022	ribosome binding	18/1458	112/18639	0.160714285714286	2.05456349206349	0.00262599365330586	0.0369659106580747
GO:0017069	snRNA binding	11/1458	54/18639	0.203703703703704	2.60413808870599	0.00269318970163801	0.0374319277518801
GO:0001784	phosphotyrosine residue binding	10/1458	47/18639	0.212765957446809	2.71998949303914	0.00296722504188615	0.0407251636998874
GO:0098847	sequence-specific single stranded DNA binding	5/1458	14/18639	0.357142857142857	4.56569664902998	0.00319857937880772	0.0433585204682824
GO:0043024	ribosomal small subunit binding	6/1458	20/18639	0.3	3.83518518518519	0.00337498221154225	0.0451918349789438
GO:0061650	ubiquitin-like protein conjugating enzyme activity	9/1458	41/18639	0.219512195121951	2.80623306233062	0.00379422891597462	0.0501935343342185
GO:0140297	DNA-binding transcription factor binding	55/1458	488/18639	0.112704918032787	1.44081410645618	0.00391049867577777	0.0511158041190951
GO:0019208	phosphatase regulator activity	18/1458	117/18639	0.153846153846154	1.9667616334283	0.00424932826930433	0.0548913228199548
GO:0003823	antigen binding	24/1458	174/18639	0.137931034482759	1.76330353341848	0.00464492063833104	0.0593037541963661
GO:0048156	tau protein binding	9/1458	43/18639	0.209302325581395	2.67571059431525	0.00530461002597944	0.0643764436943281
GO:0005126	cytokine receptor binding	34/1458	275/18639	0.123636363636364	1.58056116722783	0.00530615281270343	0.0643764436943281
GO:0005522	profilin binding	4/1458	10/18639	0.4	5.11358024691358	0.00533538832075032	0.0643764436943281
GO:0031996	thioesterase binding	4/1458	10/18639	0.4	5.11358024691358	0.00533538832075032	0.0643764436943281
GO:0098505	G-rich strand telomeric DNA binding	4/1458	10/18639	0.4	5.11358024691358	0.00533538832075032	0.0643764436943281
GO:0061133	endopeptidase activator activity	6/1458	22/18639	0.272727272727273	3.48653198653199	0.0056765652321209	0.067748572009443
GO:0019205	nucleobase-containing compound kinase activity	9/1458	44/18639	0.204545454545455	2.61489898989899	0.00621573208825857	0.0733857401387947
GO:0008009	chemokine activity	9/1458	45/18639	0.2	2.55679012345679	0.00724254985694319	0.0842160379128791
GO:0005178	integrin binding	22/1458	161/18639	0.136645962732919	1.74687523962886	0.0072864513676899	0.0842160379128791
GO:0010854	adenylate cyclase regulator activity	4/1458	11/18639	0.363636363636364	4.64870931537598	0.0078697227550877	0.0881730161743499
GO:0032794	GTPase activating protein binding	4/1458	11/18639	0.363636363636364	4.64870931537598	0.0078697227550877	0.0881730161743499
GO:0048407	platelet-derived growth factor binding	4/1458	11/18639	0.363636363636364	4.64870931537598	0.0078697227550877	0.0881730161743499
GO:0042162	telomeric DNA binding	8/1458	38/18639	0.210526315789474	2.69135802469136	0.00809547066311346	0.0897861291727129
GO:0005525	GTP binding	43/1458	378/18639	0.113756613756614	1.45425893265399	0.00846837607366081	0.0906822023375321
GO:0019001	guanyl nucleotide binding	45/1458	400/18639	0.1125	1.43819444444444	0.00873272933709989	0.0906822023375321
GO:0032561	guanyl ribonucleotide binding	45/1458	400/18639	0.1125	1.43819444444444	0.00873272933709989	0.0906822023375321
GO:0005164	tumor necrosis factor receptor binding	7/1458	31/18639	0.225806451612903	2.88669852648347	0.00876207304310626	0.0906822023375321
GO:0042625	ATPase-coupled ion transmembrane transporter activity	6/1458	24/18639	0.25	3.19598765432099	0.00895171324738096	0.0906822023375321
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	6/1458	24/18639	0.25	3.19598765432099	0.00895171324738096	0.0906822023375321
GO:0046961	proton-transporting ATPase activity, rotational mechanism	6/1458	24/18639	0.25	3.19598765432099	0.00895171324738096	0.0906822023375321
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	14/1458	89/18639	0.157303370786517	2.01095852406714	0.00900162212702311	0.0906822023375321
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	14/1458	89/18639	0.157303370786517	2.01095852406714	0.00900162212702311	0.0906822023375321
GO:0004725	protein tyrosine phosphatase activity	15/1458	98/18639	0.153061224489796	1.95672713529856	0.00900214941237796	0.0906822023375321
GO:0061135	endopeptidase regulator activity	24/1458	184/18639	0.130434782608696	1.66747181964573	0.00924603564425109	0.0922922467035245
GO:0004386	helicase activity	21/1458	155/18639	0.135483870967742	1.73201911589008	0.00946121022686362	0.0924169079065032
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	8/1458	39/18639	0.205128205128205	2.62234884457107	0.00950252182594669	0.0924169079065032
GO:0140789	histone phosphatase activity	19/1458	136/18639	0.139705882352941	1.78599310094408	0.00960366613151214	0.0924169079065032
GO:0061749	forked DNA-dependent helicase activity	9/1458	47/18639	0.191489361702128	2.44799054373522	0.00967936649293977	0.0924169079065032
GO:1990518	single-stranded 3'-5' DNA helicase activity	9/1458	47/18639	0.191489361702128	2.44799054373522	0.00967936649293977	0.0924169079065032
GO:0001618	virus receptor activity	13/1458	81/18639	0.160493827160494	2.05174516079866	0.00983158561367231	0.0930429239655058
GO:0140793	histone H2AXY142 phosphatase activity	14/1458	90/18639	0.155555555555556	1.98861454046639	0.00991440993075062	0.0930429239655058
GO:0031369	translation initiation factor binding	7/1458	32/18639	0.21875	2.79648919753086	0.0104750271828871	0.0960326504202019
GO:0003746	translation elongation factor activity	5/1458	18/18639	0.277777777777778	3.55109739368999	0.0105265776886289	0.0960326504202019
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	18/1458	128/18639	0.140625	1.79774305555556	0.0107806691173774	0.0960326504202019
GO:0140272	exogenous protein binding	13/1458	82/18639	0.158536585365854	2.02672387834989	0.0108713082852939	0.0960326504202019
GO:0043047	single-stranded telomeric DNA binding	4/1458	12/18639	0.333333333333333	4.26131687242798	0.0110824351727413	0.0960326504202019
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	4/1458	12/18639	0.333333333333333	4.26131687242798	0.0110824351727413	0.0960326504202019
GO:0140662	ATP-dependent protein folding chaperone	8/1458	40/18639	0.2	2.55679012345679	0.011083681386197	0.0960326504202019
GO:0009378	four-way junction helicase activity	9/1458	48/18639	0.1875	2.39699074074074	0.0111076016424095	0.0960326504202019
GO:0036121	double-stranded DNA helicase activity	9/1458	48/18639	0.1875	2.39699074074074	0.0111076016424095	0.0960326504202019
GO:0043138	3'-5' DNA helicase activity	9/1458	48/18639	0.1875	2.39699074074074	0.0111076016424095	0.0960326504202019
GO:0019209	kinase activator activity	20/1458	148/18639	0.135135135135135	1.72756089422756	0.0114450646333638	0.0981771950580743
GO:0019956	chemokine binding	7/1458	33/18639	0.212121212121212	2.71174710063599	0.0124188740376823	0.105704834832366
GO:0003725	double-stranded RNA binding	12/1458	75/18639	0.16	2.04543209876543	0.0131342944378662	0.1109342714829
GO:0003756	protein disulfide isomerase activity	5/1458	19/18639	0.263157894736842	3.3641975308642	0.0133832515157851	0.111324319426758
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	5/1458	19/18639	0.263157894736842	3.3641975308642	0.0133832515157851	0.111324319426758
GO:0005200	structural constituent of cytoskeleton	16/1458	112/18639	0.142857142857143	1.82627865961199	0.0135640450150989	0.111979860350215
GO:0140097	catalytic activity, acting on DNA	38/1458	336/18639	0.113095238095238	1.44580393885949	0.01388654295786	0.113786747520375
GO:0032813	tumor necrosis factor receptor superfamily binding	9/1458	50/18639	0.18	2.30111111111111	0.0144293429395191	0.117358655908089
GO:0016859	cis-trans isomerase activity	8/1458	42/18639	0.19047619047619	2.43503821281599	0.0148156429923786	0.118739442462071
GO:0048487	beta-tubulin binding	8/1458	42/18639	0.19047619047619	2.43503821281599	0.0148156429923786	0.118739442462071
GO:0019104	DNA N-glycosylase activity	4/1458	13/18639	0.307692307692308	3.9335232668566	0.0150316780530309	0.118739442462071
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	4/1458	13/18639	0.307692307692308	3.9335232668566	0.0150316780530309	0.118739442462071
GO:0016209	antioxidant activity	13/1458	86/18639	0.151162790697674	1.9324576514499	0.0159060953407703	0.124749233458327
GO:0016004	phospholipase activator activity	5/1458	20/18639	0.25	3.19598765432099	0.0167193412838661	0.129061521249018
GO:0004896	cytokine receptor activity	14/1458	96/18639	0.145833333333333	1.86432613168724	0.0170088206769271	0.129061521249018
GO:0001221	transcription coregulator binding	16/1458	115/18639	0.139130434782609	1.77863660762211	0.0171611858855706	0.129061521249018
GO:0017124	SH3 domain binding	16/1458	115/18639	0.139130434782609	1.77863660762211	0.0171611858855706	0.129061521249018
GO:0035401	histone H3Y41 kinase activity	16/1458	115/18639	0.139130434782609	1.77863660762211	0.0171611858855706	0.129061521249018
GO:0140801	histone H2AXY142 kinase activity	16/1458	115/18639	0.139130434782609	1.77863660762211	0.0171611858855706	0.129061521249018
GO:0004721	phosphoprotein phosphatase activity	22/1458	175/18639	0.125714285714286	1.60712522045855	0.0183053080245388	0.135391481436993
GO:0033218	amide binding	29/1458	247/18639	0.117408906882591	1.50094966761633	0.0183727966613041	0.135391481436993
GO:0042393	histone binding	29/1458	247/18639	0.117408906882591	1.50094966761633	0.0183727966613041	0.135391481436993
GO:0001046	core promoter sequence-specific DNA binding	8/1458	44/18639	0.181818181818182	2.32435465768799	0.0193837847839073	0.140196440732327
GO:0032036	myosin heavy chain binding	4/1458	14/18639	0.285714285714286	3.65255731922399	0.0197649175227201	0.140196440732327
GO:0004033	aldo-keto reductase (NADPH) activity	7/1458	36/18639	0.194444444444444	2.48576817558299	0.0197909365332519	0.140196440732327
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	7/1458	36/18639	0.194444444444444	2.48576817558299	0.0197909365332519	0.140196440732327
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	7/1458	36/18639	0.194444444444444	2.48576817558299	0.0197909365332519	0.140196440732327
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	7/1458	36/18639	0.194444444444444	2.48576817558299	0.0197909365332519	0.140196440732327
GO:0001846	opsonin binding	5/1458	21/18639	0.238095238095238	3.04379776601999	0.0205640239305494	0.142906951112299
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/1458	21/18639	0.238095238095238	3.04379776601999	0.0205640239305494	0.142906951112299
GO:0051010	microtubule plus-end binding	5/1458	21/18639	0.238095238095238	3.04379776601999	0.0205640239305494	0.142906951112299
GO:0000287	magnesium ion binding	27/1458	230/18639	0.117391304347826	1.50072463768116	0.0223139606344486	0.152994660434545
GO:0051020	GTPase binding	35/1458	315/18639	0.111111111111111	1.42043895747599	0.0224336384240692	0.152994660434545
GO:0022804	active transmembrane transporter activity	48/1458	457/18639	0.105032822757112	1.34273441932085	0.0224336432877612	0.152994660434545
GO:0043394	proteoglycan binding	7/1458	37/18639	0.189189189189189	2.41858525191859	0.0228103554807654	0.154603520480743
GO:0008094	ATP-dependent activity, acting on DNA	25/1458	210/18639	0.119047619047619	1.52189888300999	0.0232757990089699	0.156543614311909
GO:0035591	signaling adaptor activity	17/1458	129/18639	0.131782945736434	1.68470667049478	0.0233817420283726	0.156543614311909
GO:0030295	protein kinase activator activity	18/1458	139/18639	0.129496402877698	1.6554756195044	0.0235547708602324	0.156746293360819
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/1458	15/18639	0.266666666666667	3.40905349794239	0.0253187545895974	0.163529367878694
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/1458	15/18639	0.266666666666667	3.40905349794239	0.0253187545895974	0.163529367878694
GO:0004953	icosanoid receptor activity	4/1458	15/18639	0.266666666666667	3.40905349794239	0.0253187545895974	0.163529367878694
GO:0015556	C4-dicarboxylate transmembrane transporter activity	4/1458	15/18639	0.266666666666667	3.40905349794239	0.0253187545895974	0.163529367878694
GO:0050700	CARD domain binding	4/1458	15/18639	0.266666666666667	3.40905349794239	0.0253187545895974	0.163529367878694
GO:0008106	alcohol dehydrogenase (NADP+) activity	6/1458	30/18639	0.2	2.55679012345679	0.0264654913721305	0.169936313021049
GO:0005125	cytokine activity	27/1458	234/18639	0.115384615384615	1.47507122507123	0.0271386048552977	0.173245279832075
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	16/1458	122/18639	0.131147540983607	1.67658368751265	0.0283769426459685	0.180103370088285
GO:0051219	phosphoprotein binding	13/1458	93/18639	0.139784946236559	1.78700384972786	0.0287321463584979	0.181309751158797
GO:0000217	DNA secondary structure binding	7/1458	39/18639	0.179487179487179	2.29455523899968	0.0297710041282601	0.185596497555659
GO:0031681	G-protein beta-subunit binding	5/1458	23/18639	0.217391304347826	2.77911969940955	0.0298767051846914	0.185596497555659
GO:0051117	ATPase binding	12/1458	84/18639	0.142857142857143	1.82627865961199	0.0299185610813767	0.185596497555659
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	4/1458	16/18639	0.25	3.19598765432099	0.0317190567828885	0.194567175126321
GO:0008142	oxysterol binding	4/1458	16/18639	0.25	3.19598765432099	0.0317190567828885	0.194567175126321
GO:0019955	cytokine binding	18/1458	144/18639	0.125	1.59799382716049	0.0322123289221661	0.196495206425213
GO:0140104	molecular carrier activity	28/1458	249/18639	0.112449799196787	1.43755267985522	0.0332254582106625	0.201555542073521
GO:0019957	C-C chemokine binding	5/1458	24/18639	0.208333333333333	2.66332304526749	0.0353832820102994	0.212299692061796
GO:0060229	lipase activator activity	5/1458	24/18639	0.208333333333333	2.66332304526749	0.0353832820102994	0.212299692061796
GO:0140597	protein carrier chaperone	22/1458	188/18639	0.117021276595745	1.49599422117153	0.0374819590855045	0.215644145775873
GO:0005031	tumor necrosis factor receptor activity	3/1458	10/18639	0.3	3.83518518518519	0.0377835781333076	0.215644145775873
GO:0030957	Tat protein binding	3/1458	10/18639	0.3	3.83518518518519	0.0377835781333076	0.215644145775873
GO:0032356	oxidized DNA binding	3/1458	10/18639	0.3	3.83518518518519	0.0377835781333076	0.215644145775873
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/1458	10/18639	0.3	3.83518518518519	0.0377835781333076	0.215644145775873
GO:0051880	G-quadruplex DNA binding	3/1458	10/18639	0.3	3.83518518518519	0.0377835781333076	0.215644145775873
GO:0070513	death domain binding	3/1458	10/18639	0.3	3.83518518518519	0.0377835781333076	0.215644145775873
GO:0140940	histone H2A methyltransferase activity	3/1458	10/18639	0.3	3.83518518518519	0.0377835781333076	0.215644145775873
GO:1990259	histone H2AQ104 methyltransferase activity	3/1458	10/18639	0.3	3.83518518518519	0.0377835781333076	0.215644145775873
GO:0032934	sterol binding	10/1458	68/18639	0.147058823529412	1.87999273783588	0.0379046631463965	0.215644145775873
GO:0016018	cyclosporin A binding	4/1458	17/18639	0.235294117647059	3.0079883805374	0.038981328059126	0.220626279427425
GO:0019888	protein phosphatase regulator activity	14/1458	107/18639	0.130841121495327	1.67266643590631	0.0392230744744939	0.22085608088715
GO:0015631	tubulin binding	40/1458	385/18639	0.103896103896104	1.32820266153599	0.0400529378779415	0.22437819280602
GO:0001848	complement binding	5/1458	25/18639	0.2	2.55679012345679	0.0414753929841002	0.231167418764173
GO:0008017	microtubule binding	30/1458	276/18639	0.108695652173913	1.38955984970478	0.041815280850012	0.231884739259157
GO:0042056	chemoattractant activity	7/1458	42/18639	0.166666666666667	2.13065843621399	0.0426784654913252	0.235482186479774
GO:0030544	Hsp70 protein binding	8/1458	51/18639	0.156862745098039	2.00532558702493	0.0431389487948656	0.236832828883812
GO:0003689	DNA clamp loader activity	19/1458	160/18639	0.11875	1.51809413580247	0.0445468905540212	0.243345700638384
GO:0097110	scaffold protein binding	10/1458	70/18639	0.142857142857143	1.82627865961199	0.0449984468879318	0.244560903374335
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	6/1458	34/18639	0.176470588235294	2.25599128540305	0.0460339964278263	0.244560903374335
GO:0030332	cyclin binding	6/1458	34/18639	0.176470588235294	2.25599128540305	0.0460339964278263	0.244560903374335
GO:0000400	four-way junction DNA binding	4/1458	18/18639	0.222222222222222	2.84087791495199	0.047111256736411	0.244560903374335
GO:0050811	GABA receptor binding	4/1458	18/18639	0.222222222222222	2.84087791495199	0.047111256736411	0.244560903374335
GO:0019210	kinase inhibitor activity	12/1458	90/18639	0.133333333333333	1.70452674897119	0.0474410959841328	0.244560903374335
GO:0005080	protein kinase C binding	8/1458	52/18639	0.153846153846154	1.9667616334283	0.0476312428642233	0.244560903374335
GO:0030159	signaling receptor complex adaptor activity	8/1458	52/18639	0.153846153846154	1.9667616334283	0.0476312428642233	0.244560903374335
GO:0008200	ion channel inhibitor activity	7/1458	43/18639	0.162790697674419	2.08110824002297	0.0476735239565027	0.244560903374335
GO:0043548	phosphatidylinositol 3-kinase binding	5/1458	26/18639	0.192307692307692	2.45845204178538	0.04816177832267	0.244560903374335
GO:0070412	R-SMAD binding	5/1458	26/18639	0.192307692307692	2.45845204178538	0.04816177832267	0.244560903374335
GO:0001851	complement component C3b binding	3/1458	11/18639	0.272727272727273	3.48653198653199	0.0490012739001401	0.244560903374335
GO:0004523	RNA-DNA hybrid ribonuclease activity	3/1458	11/18639	0.272727272727273	3.48653198653199	0.0490012739001401	0.244560903374335
GO:0008199	ferric iron binding	3/1458	11/18639	0.272727272727273	3.48653198653199	0.0490012739001401	0.244560903374335
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	3/1458	11/18639	0.272727272727273	3.48653198653199	0.0490012739001401	0.244560903374335
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	3/1458	11/18639	0.272727272727273	3.48653198653199	0.0490012739001401	0.244560903374335
GO:0019206	nucleoside kinase activity	3/1458	11/18639	0.272727272727273	3.48653198653199	0.0490012739001401	0.244560903374335
GO:0019864	IgG binding	3/1458	11/18639	0.272727272727273	3.48653198653199	0.0490012739001401	0.244560903374335
GO:0050786	RAGE receptor binding	3/1458	11/18639	0.272727272727273	3.48653198653199	0.0490012739001401	0.244560903374335
GO:0061631	ubiquitin conjugating enzyme activity	6/1458	35/18639	0.171428571428571	2.19153439153439	0.0520282245730781	0.258493170050859
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	16/1458	132/18639	0.121212121212121	1.54956977179199	0.052752454611932	0.258765107451946
GO:0005518	collagen binding	10/1458	72/18639	0.138888888888889	1.77554869684499	0.0529396027956705	0.258765107451946
GO:0042379	chemokine receptor binding	10/1458	72/18639	0.138888888888889	1.77554869684499	0.0529396027956705	0.258765107451946
GO:0016248	channel inhibitor activity	7/1458	44/18639	0.159090909090909	2.03381032547699	0.0530256367729397	0.258765107451946
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	36/1458	349/18639	0.103151862464183	1.31868831582299	0.0536903222596474	0.260849441774747
GO:0140713	histone chaperone activity	19/1458	164/18639	0.115853658536585	1.48106744956338	0.0547634263836041	0.264890934666068
GO:0008301	DNA binding, bending	4/1458	19/18639	0.210526315789474	2.69135802469136	0.0561053914619111	0.269011876965845
GO:0070003	threonine-type peptidase activity	4/1458	19/18639	0.210526315789474	2.69135802469136	0.0561053914619111	0.269011876965845
GO:0015485	cholesterol binding	8/1458	54/18639	0.148148148148148	1.89391860996799	0.0575016132723688	0.273319356593338
GO:0051287	NAD binding	8/1458	54/18639	0.148148148148148	1.89391860996799	0.0575016132723688	0.273319356593338
GO:0004869	cysteine-type endopeptidase inhibitor activity	6/1458	36/18639	0.166666666666667	2.13065843621399	0.0584756821810433	0.276751288943041
GO:0141110	transporter inhibitor activity	7/1458	45/18639	0.155555555555556	1.98861454046639	0.0587392431095324	0.276805531906724
GO:0030695	GTPase regulator activity	48/1458	489/18639	0.098159509202454	1.254866318261	0.0607198906042966	0.28318700299825
GO:0004032	aldose reductase (NADPH) activity	3/1458	12/18639	0.25	3.19598765432099	0.0616408868092731	0.28318700299825
GO:0004126	cytidine deaminase activity	3/1458	12/18639	0.25	3.19598765432099	0.0616408868092731	0.28318700299825
GO:0008179	adenylate cyclase binding	3/1458	12/18639	0.25	3.19598765432099	0.0616408868092731	0.28318700299825
GO:0010853	cyclase activator activity	3/1458	12/18639	0.25	3.19598765432099	0.0616408868092731	0.28318700299825
GO:0036009	protein-glutamine N-methyltransferase activity	3/1458	12/18639	0.25	3.19598765432099	0.0616408868092731	0.28318700299825
GO:0004860	protein kinase inhibitor activity	11/1458	84/18639	0.130952380952381	1.67408877131099	0.062403352958245	0.284362050040425
GO:0060589	nucleoside-triphosphatase regulator activity	48/1458	490/18639	0.0979591836734694	1.25230536659108	0.0624146211837363	0.284362050040425
GO:0051019	mitogen-activated protein kinase binding	5/1458	28/18639	0.178571428571429	2.28284832451499	0.0633315701503129	0.284992065676408
GO:0051537	2 iron, 2 sulfur cluster binding	5/1458	28/18639	0.178571428571429	2.28284832451499	0.0633315701503129	0.284992065676408
GO:0097718	disordered domain specific binding	5/1458	28/18639	0.178571428571429	2.28284832451499	0.0633315701503129	0.284992065676408
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	4/1458	20/18639	0.2	2.55679012345679	0.0659519040064224	0.294370693492081
GO:0010851	cyclase regulator activity	4/1458	20/18639	0.2	2.55679012345679	0.0659519040064224	0.294370693492081
GO:0019003	GDP binding	10/1458	75/18639	0.133333333333333	1.70452674897119	0.0665009053486391	0.295619409201643
GO:0019212	phosphatase inhibitor activity	8/1458	56/18639	0.142857142857143	1.82627865961199	0.0685769666070653	0.303618989252249
GO:0030414	peptidase inhibitor activity	19/1458	169/18639	0.112426035502959	1.43724888596683	0.0697120909290048	0.307405123855611
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	5/1458	29/18639	0.172413793103448	2.2041294167731	0.0718120724712101	0.314142054077246
GO:0097472	cyclin-dependent protein kinase activity	5/1458	29/18639	0.172413793103448	2.2041294167731	0.0718120724712101	0.314142054077246
GO:0004601	peroxidase activity	8/1458	57/18639	0.140350877192982	1.79423868312757	0.0745720338976802	0.324354558909719
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	3/1458	13/18639	0.230769230769231	2.95014245014245	0.0756236494361457	0.324354558909719
GO:0005035	death receptor activity	3/1458	13/18639	0.230769230769231	2.95014245014245	0.0756236494361457	0.324354558909719
GO:0019855	calcium channel inhibitor activity	3/1458	13/18639	0.230769230769231	2.95014245014245	0.0756236494361457	0.324354558909719
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	3/1458	13/18639	0.230769230769231	2.95014245014245	0.0756236494361457	0.324354558909719
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	4/1458	21/18639	0.19047619047619	2.43503821281599	0.0766314052007454	0.326292441285839
GO:0051540	metal cluster binding	10/1458	77/18639	0.12987012987013	1.66025332691999	0.0766698086081479	0.326292441285839
GO:0140693	molecular condensate scaffold activity	7/1458	48/18639	0.145833333333333	1.86432613168724	0.0780727238016592	0.330980118664949
GO:0004866	endopeptidase inhibitor activity	18/1458	161/18639	0.111801242236025	1.42926155969634	0.0791251718390491	0.334151687227984
GO:0005096	GTPase activator activity	28/1458	271/18639	0.103321033210332	1.32085098628764	0.0794944394426181	0.334424883172394
GO:0016776	phosphotransferase activity, phosphate group as acceptor	6/1458	39/18639	0.153846153846154	1.9667616334283	0.0805492289595606	0.336393048419495
GO:0004713	protein tyrosine kinase activity	16/1458	140/18639	0.114285714285714	1.46102292768959	0.0806357317733482	0.336393048419495
GO:0001965	G-protein alpha-subunit binding	5/1458	30/18639	0.166666666666667	2.13065843621399	0.080881388691026	0.336393048419495
GO:0035254	glutamate receptor binding	7/1458	49/18639	0.142857142857143	1.82627865961199	0.0852491155920393	0.35322086384928
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	8/1458	59/18639	0.135593220338983	1.73341703285206	0.0874798281623315	0.357023357363535
GO:0036002	pre-mRNA binding	8/1458	59/18639	0.135593220338983	1.73341703285206	0.0874798281623315	0.357023357363535
GO:0034062	5'-3' RNA polymerase activity	4/1458	22/18639	0.181818181818182	2.32435465768799	0.0881177867445519	0.357023357363535
GO:0070034	telomerase RNA binding	4/1458	22/18639	0.181818181818182	2.32435465768799	0.0881177867445519	0.357023357363535
GO:0097747	RNA polymerase activity	4/1458	22/18639	0.181818181818182	2.32435465768799	0.0881177867445519	0.357023357363535
GO:0140517	protein-RNA adaptor activity	4/1458	22/18639	0.181818181818182	2.32435465768799	0.0881177867445519	0.357023357363535
GO:0008191	metalloendopeptidase inhibitor activity	3/1458	14/18639	0.214285714285714	2.73941798941799	0.0908578490488981	0.364094592174052
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/1458	14/18639	0.214285714285714	2.73941798941799	0.0908578490488981	0.364094592174052
GO:0019763	immunoglobulin receptor activity	3/1458	14/18639	0.214285714285714	2.73941798941799	0.0908578490488981	0.364094592174052
GO:0048020	CCR chemokine receptor binding	7/1458	50/18639	0.14	1.78975308641975	0.0927885688688336	0.370479449519925
GO:0001530	lipopolysaccharide binding	6/1458	41/18639	0.146341463414634	1.87082204155375	0.0975150075674201	0.380114593924068
GO:0019903	protein phosphatase binding	16/1458	144/18639	0.111111111111111	1.42043895747599	0.0976211726077815	0.380114593924068
GO:0033192	calmodulin-dependent protein phosphatase activity	10/1458	81/18639	0.123456790123457	1.57826550830666	0.0997536194166976	0.380114593924068
GO:0140791	histone H2AXS140 phosphatase activity	10/1458	81/18639	0.123456790123457	1.57826550830666	0.0997536194166976	0.380114593924068
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	10/1458	81/18639	0.123456790123457	1.57826550830666	0.0997536194166976	0.380114593924068
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	10/1458	81/18639	0.123456790123457	1.57826550830666	0.0997536194166976	0.380114593924068
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	10/1458	81/18639	0.123456790123457	1.57826550830666	0.0997536194166976	0.380114593924068
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	10/1458	81/18639	0.123456790123457	1.57826550830666	0.0997536194166976	0.380114593924068
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	10/1458	81/18639	0.123456790123457	1.57826550830666	0.0997536194166976	0.380114593924068
GO:1990439	MAP kinase serine/threonine phosphatase activity	10/1458	81/18639	0.123456790123457	1.57826550830666	0.0997536194166976	0.380114593924068
GO:0004602	glutathione peroxidase activity	4/1458	23/18639	0.173913043478261	2.22329575952764	0.100379067072944	0.380114593924068
GO:0016493	C-C chemokine receptor activity	4/1458	23/18639	0.173913043478261	2.22329575952764	0.100379067072944	0.380114593924068
GO:0043274	phospholipase binding	4/1458	23/18639	0.173913043478261	2.22329575952764	0.100379067072944	0.380114593924068
GO:0030515	snoRNA binding	5/1458	32/18639	0.15625	1.99749228395062	0.100740753034521	0.380114593924068
GO:0051059	NF-kappaB binding	5/1458	32/18639	0.15625	1.99749228395062	0.100740753034521	0.380114593924068
GO:0120015	sterol transfer activity	5/1458	32/18639	0.15625	1.99749228395062	0.100740753034521	0.380114593924068
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	10/1458	82/18639	0.121951219512195	1.55901836796146	0.106095577197716	0.396971408504925
GO:0033549	MAP kinase phosphatase activity	10/1458	82/18639	0.121951219512195	1.55901836796146	0.106095577197716	0.396971408504925
GO:0004722	protein serine/threonine phosphatase activity	12/1458	103/18639	0.116504854368932	1.48939230492629	0.106582590542504	0.396971408504925
GO:0031492	nucleosomal DNA binding	6/1458	42/18639	0.142857142857143	1.82627865961199	0.106654431246769	0.396971408504925
GO:0000774	adenyl-nucleotide exchange factor activity	3/1458	15/18639	0.2	2.55679012345679	0.107242622663723	0.39781216109719
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	7/1458	52/18639	0.134615384615385	1.72091642924976	0.108940547715472	0.402749903675381
GO:0019239	deaminase activity	5/1458	33/18639	0.151515151515152	1.93696221473999	0.111500087368069	0.410829180973624
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	10/1458	83/18639	0.120481927710843	1.5402350141306	0.112663547756687	0.412216192204797
GO:0001091	RNA polymerase II general transcription initiation factor binding	4/1458	24/18639	0.166666666666667	2.13065843621399	0.113378224085472	0.412216192204797
GO:0035035	histone acetyltransferase binding	4/1458	24/18639	0.166666666666667	2.13065843621399	0.113378224085472	0.412216192204797
GO:0050699	WW domain binding	4/1458	24/18639	0.166666666666667	2.13065843621399	0.113378224085472	0.412216192204797
GO:0004712	protein serine/threonine/tyrosine kinase activity	6/1458	43/18639	0.13953488372093	1.78380706287683	0.116218902699245	0.421149687009145
GO:0017018	myosin phosphatase activity	10/1458	84/18639	0.119047619047619	1.52189888300999	0.119455465972693	0.431454281704002
GO:0031491	nucleosome binding	9/1458	74/18639	0.121621621621622	1.5548048048048	0.122539486514137	0.441142151450892
GO:0004708	MAP kinase kinase activity	3/1458	16/18639	0.1875	2.39699074074074	0.124671137866993	0.441577127025672
GO:0005159	insulin-like growth factor receptor binding	3/1458	16/18639	0.1875	2.39699074074074	0.124671137866993	0.441577127025672
GO:0034450	ubiquitin-ubiquitin ligase activity	3/1458	16/18639	0.1875	2.39699074074074	0.124671137866993	0.441577127025672
GO:0043023	ribosomal large subunit binding	3/1458	16/18639	0.1875	2.39699074074074	0.124671137866993	0.441577127025672
GO:0097027	ubiquitin-protein transferase activator activity	3/1458	16/18639	0.1875	2.39699074074074	0.124671137866993	0.441577127025672
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	7/1458	54/18639	0.12962962962963	1.65717878372199	0.126484070806521	0.445773973096006
GO:0019211	phosphatase activator activity	4/1458	25/18639	0.16	2.04543209876543	0.127074001438115	0.445773973096006
GO:0120020	cholesterol transfer activity	4/1458	25/18639	0.16	2.04543209876543	0.127074001438115	0.445773973096006
GO:0000510	H3-H4 histone complex chaperone activity	16/1458	151/18639	0.105960264900662	1.35459079388439	0.132330947047078	0.458357665166219
GO:0140584	chromatin extrusion motor activity	16/1458	151/18639	0.105960264900662	1.35459079388439	0.132330947047078	0.458357665166219
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	16/1458	151/18639	0.105960264900662	1.35459079388439	0.132330947047078	0.458357665166219
GO:0140849	ATP-dependent H2AZ histone chaperone activity	16/1458	151/18639	0.105960264900662	1.35459079388439	0.132330947047078	0.458357665166219
GO:0120013	lipid transfer activity	8/1458	65/18639	0.123076923076923	1.57340930674264	0.133404240342283	0.460622188351656
GO:0005085	guanyl-nucleotide exchange factor activity	23/1458	230/18639	0.1	1.2783950617284	0.133830343828718	0.460644882520164
GO:0015616	DNA translocase activity	16/1458	152/18639	0.105263157894737	1.34567901234568	0.137801911901687	0.470801557656038
GO:0140674	ATP-dependent histone chaperone activity	16/1458	152/18639	0.105263157894737	1.34567901234568	0.137801911901687	0.470801557656038
GO:0051536	iron-sulfur cluster binding	9/1458	76/18639	0.118421052631579	1.51388888888889	0.138067487764339	0.470801557656038
GO:0001637	G protein-coupled chemoattractant receptor activity	4/1458	26/18639	0.153846153846154	1.9667616334283	0.141421678368196	0.477125668013754
GO:0004950	chemokine receptor activity	4/1458	26/18639	0.153846153846154	1.9667616334283	0.141421678368196	0.477125668013754
GO:0050750	low-density lipoprotein particle receptor binding	4/1458	26/18639	0.153846153846154	1.9667616334283	0.141421678368196	0.477125668013754
GO:0004550	nucleoside diphosphate kinase activity	3/1458	17/18639	0.176470588235294	2.25599128540305	0.143033239968679	0.477125668013754
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	3/1458	17/18639	0.176470588235294	2.25599128540305	0.143033239968679	0.477125668013754
GO:0051787	misfolded protein binding	3/1458	17/18639	0.176470588235294	2.25599128540305	0.143033239968679	0.477125668013754
GO:1990226	histone methyltransferase binding	3/1458	17/18639	0.176470588235294	2.25599128540305	0.143033239968679	0.477125668013754
GO:0061775	cohesin loader activity	16/1458	153/18639	0.104575163398693	1.33688372468329	0.143398424812877	0.477125668013754
GO:0003713	transcription coactivator activity	25/1458	256/18639	0.09765625	1.24843267746914	0.147454820736692	0.489140160631082
GO:0004197	cysteine-type endopeptidase activity	10/1458	88/18639	0.113636363636364	1.45272166105499	0.148804553623007	0.492130722524282
GO:0008320	protein transmembrane transporter activity	4/1458	27/18639	0.148148148148148	1.89391860996799	0.156373795751148	0.51503643649149
GO:0003727	single-stranded RNA binding	10/1458	89/18639	0.112359550561798	1.43639894576224	0.156668642794315	0.51503643649149
GO:0043130	ubiquitin binding	11/1458	100/18639	0.11	1.40623456790123	0.157752446010148	0.517051300654157
GO:0005504	fatty acid binding	6/1458	47/18639	0.127659574468085	1.63199369582348	0.158471664781747	0.517862761697496
GO:1990841	promoter-specific chromatin binding	8/1458	68/18639	0.117647058823529	1.5039941902687	0.160192351928617	0.521932351387601
GO:0019902	phosphatase binding	19/1458	190/18639	0.1	1.2783950617284	0.160922811184872	0.522331275669839
GO:0008409	5'-3' exonuclease activity	3/1458	18/18639	0.166666666666667	2.13065843621399	0.162217636615132	0.522331275669839
GO:0031690	adrenergic receptor binding	3/1458	18/18639	0.166666666666667	2.13065843621399	0.162217636615132	0.522331275669839
GO:1990381	ubiquitin-specific protease binding	3/1458	18/18639	0.166666666666667	2.13065843621399	0.162217636615132	0.522331275669839
GO:0003712	transcription coregulator activity	45/1458	495/18639	0.0909090909090909	1.162177328844	0.163028787054962	0.523408211071195
GO:0031267	small GTPase binding	27/1458	283/18639	0.0954063604240283	1.21967020023557	0.164518883588606	0.526652286239911
GO:0016247	channel regulator activity	17/1458	168/18639	0.101190476190476	1.29361405055849	0.165084651718255	0.526927173216989
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	6/1458	48/18639	0.125	1.59799382716049	0.169957227778903	0.537529095361114
GO:0016791	phosphatase activity	26/1458	273/18639	0.0952380952380952	1.217519106408	0.17212393984399	0.537529095361114
GO:0043531	ADP binding	5/1458	38/18639	0.131578947368421	1.6820987654321	0.172745215979217	0.537529095361114
GO:0140658	ATP-dependent chromatin remodeler activity	16/1458	158/18639	0.10126582278481	1.29457727769964	0.173215599720948	0.537529095361114
GO:0141108	transporter regulator activity	17/1458	170/18639	0.1	1.2783950617284	0.17708256062108	0.537529095361114
GO:0019838	growth factor binding	14/1458	136/18639	0.102941176470588	1.31599491648511	0.17716907818467	0.537529095361114
GO:0001094	TFIID-class transcription factor complex binding	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:0004090	carbonyl reductase (NADPH) activity	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:0004955	prostaglandin receptor activity	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:0005345	purine nucleobase transmembrane transporter activity	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:0035256	G protein-coupled glutamate receptor binding	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:0047429	nucleoside triphosphate diphosphatase activity	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:0050815	phosphoserine residue binding	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:0097177	mitochondrial ribosome binding	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:1905394	retromer complex binding	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/1458	10/18639	0.2	2.55679012345679	0.181309989150012	0.537529095361114
GO:0043178	alcohol binding	10/1458	92/18639	0.108695652173913	1.38955984970478	0.181450486406727	0.537529095361114
GO:0001222	transcription corepressor binding	6/1458	49/18639	0.122448979591837	1.56538170823885	0.181776964363116	0.537529095361114
GO:0060590	ATPase regulator activity	6/1458	49/18639	0.122448979591837	1.56538170823885	0.181776964363116	0.537529095361114
GO:0008574	plus-end-directed microtubule motor activity	3/1458	19/18639	0.157894736842105	2.01851851851852	0.182113682581361	0.537529095361114
GO:0034987	immunoglobulin receptor binding	3/1458	19/18639	0.157894736842105	2.01851851851852	0.182113682581361	0.537529095361114
GO:0050145	nucleoside monophosphate kinase activity	3/1458	19/18639	0.157894736842105	2.01851851851852	0.182113682581361	0.537529095361114
GO:0016922	nuclear receptor binding	14/1458	137/18639	0.102189781021898	1.306389114175	0.184097047525867	0.541926429446117
GO:0099106	ion channel regulator activity	16/1458	160/18639	0.1	1.2783950617284	0.185966529359354	0.54549649973914
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	5/1458	39/18639	0.128205128205128	1.63896802785692	0.186303449364461	0.54549649973914
GO:0003785	actin monomer binding	4/1458	29/18639	0.137931034482759	1.76330353341848	0.1878918350921	0.54722873987036
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	4/1458	29/18639	0.137931034482759	1.76330353341848	0.1878918350921	0.54722873987036
GO:0035173	histone kinase activity	33/1458	360/18639	0.0916666666666667	1.1718621399177	0.192803936271333	0.560049529169111
GO:0015026	coreceptor activity	7/1458	61/18639	0.114754098360656	1.46701072657357	0.197789018931541	0.57301409706288
GO:0061791	GTPase motor activity	5/1458	40/18639	0.125	1.59799382716049	0.200231004028691	0.574098497785813
GO:1990606	membrane scission GTPase motor activity	5/1458	40/18639	0.125	1.59799382716049	0.200231004028691	0.574098497785813
GO:0031490	chromatin DNA binding	13/1458	128/18639	0.1015625	1.2983699845679	0.201089041140294	0.574098497785813
GO:0001614	purinergic nucleotide receptor activity	3/1458	20/18639	0.15	1.91759259259259	0.202612819976939	0.574098497785813
GO:0016502	nucleotide receptor activity	3/1458	20/18639	0.15	1.91759259259259	0.202612819976939	0.574098497785813
GO:0042578	phosphoric ester hydrolase activity	33/1458	363/18639	0.0909090909090909	1.162177328844	0.20615586580914	0.574098497785813
GO:0005048	signal sequence binding	6/1458	51/18639	0.117647058823529	1.5039941902687	0.206341662034144	0.574098497785813
GO:0004954	prostanoid receptor activity	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0005536	D-glucose binding	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0008432	JUN kinase binding	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0015205	nucleobase transmembrane transporter activity	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0015217	ADP transmembrane transporter activity	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0032050	clathrin heavy chain binding	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0032404	mismatch repair complex binding	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0034511	U3 snoRNA binding	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0034713	type I transforming growth factor beta receptor binding	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0050998	nitric-oxide synthase binding	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0140537	transcription regulator activator activity	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/1458	11/18639	0.181818181818182	2.32435465768799	0.210711925872206	0.574098497785813
GO:0042169	SH2 domain binding	5/1458	41/18639	0.121951219512195	1.55901836796146	0.214497114648312	0.58296493040556
GO:0003774	cytoskeletal motor activity	15/1458	153/18639	0.0980392156862745	1.25332849189058	0.216686792479488	0.587461970722168
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/1458	31/18639	0.129032258064516	1.64954201513341	0.221218103241739	0.595336954312327
GO:0008327	methyl-CpG binding	4/1458	31/18639	0.129032258064516	1.64954201513341	0.221218103241739	0.595336954312327
GO:0070325	lipoprotein particle receptor binding	4/1458	31/18639	0.129032258064516	1.64954201513341	0.221218103241739	0.595336954312327
GO:0005496	steroid binding	11/1458	108/18639	0.101851851851852	1.30206904435299	0.223312041529179	0.597380718342389
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	3/1458	21/18639	0.142857142857143	1.82627865961199	0.223609722439637	0.597380718342389
GO:0072542	protein phosphatase activator activity	3/1458	21/18639	0.142857142857143	1.82627865961199	0.223609722439637	0.597380718342389
GO:0051879	Hsp90 protein binding	5/1458	42/18639	0.119047619047619	1.52189888300999	0.229070450243115	0.610483869822671
GO:0004864	protein phosphatase inhibitor activity	6/1458	53/18639	0.113207547169811	1.44723969252271	0.232004145183257	0.613832654002932
GO:0005246	calcium channel regulator activity	6/1458	53/18639	0.113207547169811	1.44723969252271	0.232004145183257	0.613832654002932
GO:0140296	general transcription initiation factor binding	6/1458	53/18639	0.113207547169811	1.44723969252271	0.232004145183257	0.613832654002932
GO:0022884	macromolecule transmembrane transporter activity	4/1458	32/18639	0.125	1.59799382716049	0.238429153271341	0.619947640342495
GO:0004859	phospholipase inhibitor activity	2/1458	12/18639	0.166666666666667	2.13065843621399	0.240526133684793	0.619947640342495
GO:0005049	nuclear export signal receptor activity	2/1458	12/18639	0.166666666666667	2.13065843621399	0.240526133684793	0.619947640342495
GO:0016273	arginine N-methyltransferase activity	2/1458	12/18639	0.166666666666667	2.13065843621399	0.240526133684793	0.619947640342495
GO:0016274	protein-arginine N-methyltransferase activity	2/1458	12/18639	0.166666666666667	2.13065843621399	0.240526133684793	0.619947640342495
GO:0016801	hydrolase activity, acting on ether bonds	2/1458	12/18639	0.166666666666667	2.13065843621399	0.240526133684793	0.619947640342495
GO:0016803	ether hydrolase activity	2/1458	12/18639	0.166666666666667	2.13065843621399	0.240526133684793	0.619947640342495
GO:0035259	nuclear glucocorticoid receptor binding	2/1458	12/18639	0.166666666666667	2.13065843621399	0.240526133684793	0.619947640342495
GO:0070679	inositol 1,4,5 trisphosphate binding	2/1458	12/18639	0.166666666666667	2.13065843621399	0.240526133684793	0.619947640342495
GO:0097371	MDM2/MDM4 family protein binding	2/1458	12/18639	0.166666666666667	2.13065843621399	0.240526133684793	0.619947640342495
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/1458	12/18639	0.166666666666667	2.13065843621399	0.240526133684793	0.619947640342495
GO:0017022	myosin binding	8/1458	76/18639	0.105263157894737	1.34567901234568	0.242099192263196	0.622540780105362
GO:0031683	G-protein beta/gamma-subunit complex binding	3/1458	22/18639	0.136363636363636	1.74326599326599	0.245003185970441	0.628536210737252
GO:0004674	protein serine/threonine kinase activity	38/1458	433/18639	0.0877598152424942	1.12191714424201	0.251097798025457	0.642669888652568
GO:0071889	14-3-3 protein binding	4/1458	33/18639	0.121212121212121	1.54956977179199	0.25593661063731	0.65353115925527
GO:0030547	signaling receptor inhibitor activity	5/1458	44/18639	0.113636363636364	1.45272166105499	0.259011972857958	0.65984952714162
GO:0008171	O-methyltransferase activity	3/1458	23/18639	0.130434782608696	1.66747181964573	0.266696803805065	0.675041425217966
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	3/1458	23/18639	0.130434782608696	1.66747181964573	0.266696803805065	0.675041425217966
GO:0005542	folic acid binding	2/1458	13/18639	0.153846153846154	1.9667616334283	0.270508403548183	0.675041425217966
GO:0030955	potassium ion binding	2/1458	13/18639	0.153846153846154	1.9667616334283	0.270508403548183	0.675041425217966
GO:0031432	titin binding	2/1458	13/18639	0.153846153846154	1.9667616334283	0.270508403548183	0.675041425217966
GO:0031994	insulin-like growth factor I binding	2/1458	13/18639	0.153846153846154	1.9667616334283	0.270508403548183	0.675041425217966
GO:0043560	insulin receptor substrate binding	2/1458	13/18639	0.153846153846154	1.9667616334283	0.270508403548183	0.675041425217966
GO:0071837	HMG box domain binding	2/1458	13/18639	0.153846153846154	1.9667616334283	0.270508403548183	0.675041425217966
GO:0140666	annealing activity	2/1458	13/18639	0.153846153846154	1.9667616334283	0.270508403548183	0.675041425217966
GO:0016835	carbon-oxygen lyase activity	8/1458	79/18639	0.10126582278481	1.29457727769964	0.275914562083814	0.683869501507964
GO:0033293	monocarboxylic acid binding	8/1458	79/18639	0.10126582278481	1.29457727769964	0.275914562083814	0.683869501507964
GO:0046332	SMAD binding	8/1458	79/18639	0.10126582278481	1.29457727769964	0.275914562083814	0.683869501507964
GO:0030145	manganese ion binding	7/1458	68/18639	0.102941176470588	1.31599491648511	0.281142943874813	0.695258901744469
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	3/1458	24/18639	0.125	1.59799382716049	0.288599458050721	0.707326350311812
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	3/1458	24/18639	0.125	1.59799382716049	0.288599458050721	0.707326350311812
GO:0070840	dynein complex binding	3/1458	24/18639	0.125	1.59799382716049	0.288599458050721	0.707326350311812
GO:0140612	DNA damage sensor activity	3/1458	24/18639	0.125	1.59799382716049	0.288599458050721	0.707326350311812
GO:0140996	histone H3 kinase activity	31/1458	357/18639	0.0868347338935574	1.11009094996023	0.297340106315067	0.721869318532329
GO:0030971	receptor tyrosine kinase binding	8/1458	81/18639	0.0987654320987654	1.26261240664533	0.299135750628742	0.721869318532329
GO:0005347	ATP transmembrane transporter activity	2/1458	14/18639	0.142857142857143	1.82627865961199	0.300450162631397	0.721869318532329
GO:0008494	translation activator activity	2/1458	14/18639	0.142857142857143	1.82627865961199	0.300450162631397	0.721869318532329
GO:0016530	metallochaperone activity	2/1458	14/18639	0.142857142857143	1.82627865961199	0.300450162631397	0.721869318532329
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/1458	14/18639	0.142857142857143	1.82627865961199	0.300450162631397	0.721869318532329
GO:0030983	mismatched DNA binding	2/1458	14/18639	0.142857142857143	1.82627865961199	0.300450162631397	0.721869318532329
GO:0042043	neurexin family protein binding	2/1458	14/18639	0.142857142857143	1.82627865961199	0.300450162631397	0.721869318532329
GO:1990825	sequence-specific mRNA binding	2/1458	14/18639	0.142857142857143	1.82627865961199	0.300450162631397	0.721869318532329
GO:0001664	G protein-coupled receptor binding	26/1458	297/18639	0.0875420875420875	1.119133724072	0.302831345640303	0.726001784962996
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	3/1458	25/18639	0.12	1.53407407407407	0.310625656679713	0.739841585757755
GO:0017025	TBP-class protein binding	3/1458	25/18639	0.12	1.53407407407407	0.310625656679713	0.739841585757755
GO:0042974	nuclear retinoic acid receptor binding	3/1458	25/18639	0.12	1.53407407407407	0.310625656679713	0.739841585757755
GO:0070063	RNA polymerase binding	6/1458	59/18639	0.101694915254237	1.30006277463905	0.313859475953402	0.745925767525617
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	12/1458	130/18639	0.0923076923076923	1.18005698005698	0.318162029872631	0.753195718363749
GO:0106310	protein serine kinase activity	31/1458	361/18639	0.0858725761772853	1.09779077322937	0.319583266625546	0.753195718363749
GO:0038187	pattern recognition receptor activity	5/1458	48/18639	0.104166666666667	1.33166152263374	0.32118965918779	0.753195718363749
GO:0004559	alpha-mannosidase activity	2/1458	15/18639	0.133333333333333	1.70452674897119	0.330174399549501	0.753195718363749
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/1458	15/18639	0.133333333333333	1.70452674897119	0.330174399549501	0.753195718363749
GO:0005523	tropomyosin binding	2/1458	15/18639	0.133333333333333	1.70452674897119	0.330174399549501	0.753195718363749
GO:0016846	carbon-sulfur lyase activity	2/1458	15/18639	0.133333333333333	1.70452674897119	0.330174399549501	0.753195718363749
GO:0031005	filamin binding	2/1458	15/18639	0.133333333333333	1.70452674897119	0.330174399549501	0.753195718363749
GO:0033130	acetylcholine receptor binding	2/1458	15/18639	0.133333333333333	1.70452674897119	0.330174399549501	0.753195718363749
GO:0050780	dopamine receptor binding	2/1458	15/18639	0.133333333333333	1.70452674897119	0.330174399549501	0.753195718363749
GO:0120283	protein serine/threonine kinase binding	2/1458	15/18639	0.133333333333333	1.70452674897119	0.330174399549501	0.753195718363749
GO:0141050	histone H3K deacetylase activity	2/1458	15/18639	0.133333333333333	1.70452674897119	0.330174399549501	0.753195718363749
GO:0141051	histone H4K deacetylase activity	2/1458	15/18639	0.133333333333333	1.70452674897119	0.330174399549501	0.753195718363749
GO:0003714	transcription corepressor activity	18/1458	204/18639	0.0882352941176471	1.12799564270153	0.33201017056326	0.753195718363749
GO:0004112	cyclic-nucleotide phosphodiesterase activity	3/1458	26/18639	0.115384615384615	1.47507122507123	0.332695740807303	0.753195718363749
GO:0004529	DNA exonuclease activity	3/1458	26/18639	0.115384615384615	1.47507122507123	0.332695740807303	0.753195718363749
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/1458	26/18639	0.115384615384615	1.47507122507123	0.332695740807303	0.753195718363749
GO:0008198	ferrous iron binding	3/1458	26/18639	0.115384615384615	1.47507122507123	0.332695740807303	0.753195718363749
GO:0019865	immunoglobulin binding	3/1458	26/18639	0.115384615384615	1.47507122507123	0.332695740807303	0.753195718363749
GO:0050681	nuclear androgen receptor binding	3/1458	26/18639	0.115384615384615	1.47507122507123	0.332695740807303	0.753195718363749
GO:0052742	phosphatidylinositol kinase activity	3/1458	26/18639	0.115384615384615	1.47507122507123	0.332695740807303	0.753195718363749
GO:0097602	cullin family protein binding	3/1458	26/18639	0.115384615384615	1.47507122507123	0.332695740807303	0.753195718363749
GO:0120014	phospholipid transfer activity	3/1458	26/18639	0.115384615384615	1.47507122507123	0.332695740807303	0.753195718363749
GO:0032182	ubiquitin-like protein binding	11/1458	120/18639	0.0916666666666667	1.1718621399177	0.337249067047019	0.761933077402524
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	6/1458	61/18639	0.0983606557377049	1.25743776563449	0.342185529486391	0.771498380648988
GO:0141003	histone H2AX kinase activity	30/1458	354/18639	0.0847457627118644	1.08338564553254	0.350166821472591	0.787875348313329
GO:0004364	glutathione transferase activity	3/1458	27/18639	0.111111111111111	1.42043895747599	0.354735983939321	0.794898184419132
GO:0035255	ionotropic glutamate receptor binding	3/1458	27/18639	0.111111111111111	1.42043895747599	0.354735983939321	0.794898184419132
GO:0000062	fatty-acyl-CoA binding	2/1458	16/18639	0.125	1.59799382716049	0.359532008361288	0.797507364001403
GO:0015923	mannosidase activity	2/1458	16/18639	0.125	1.59799382716049	0.359532008361288	0.797507364001403
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/1458	16/18639	0.125	1.59799382716049	0.359532008361288	0.797507364001403
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/1458	16/18639	0.125	1.59799382716049	0.359532008361288	0.797507364001403
GO:0055102	lipase inhibitor activity	2/1458	16/18639	0.125	1.59799382716049	0.359532008361288	0.797507364001403
GO:0005507	copper ion binding	6/1458	63/18639	0.0952380952380952	1.217519106408	0.370747831709228	0.820728062936961
GO:0016779	nucleotidyltransferase activity	12/1458	136/18639	0.0882352941176471	1.12799564270153	0.375594569559303	0.827186210013707
GO:0019789	SUMO transferase activity	3/1458	28/18639	0.107142857142857	1.36970899470899	0.376678602009885	0.827186210013707
GO:0046625	sphingolipid binding	3/1458	28/18639	0.107142857142857	1.36970899470899	0.376678602009885	0.827186210013707
GO:0046875	ephrin receptor binding	3/1458	28/18639	0.107142857142857	1.36970899470899	0.376678602009885	0.827186210013707
GO:0030331	nuclear estrogen receptor binding	4/1458	40/18639	0.1	1.2783950617284	0.382717518068807	0.83877012942026
GO:0008429	phosphatidylethanolamine binding	2/1458	17/18639	0.117647058823529	1.5039941902687	0.388398510813636	0.842809416745795
GO:0030169	low-density lipoprotein particle binding	2/1458	17/18639	0.117647058823529	1.5039941902687	0.388398510813636	0.842809416745795
GO:0045125	bioactive lipid receptor activity	2/1458	17/18639	0.117647058823529	1.5039941902687	0.388398510813636	0.842809416745795
GO:0046965	nuclear retinoid X receptor binding	2/1458	17/18639	0.117647058823529	1.5039941902687	0.388398510813636	0.842809416745795
GO:1901567	fatty acid derivative binding	2/1458	17/18639	0.117647058823529	1.5039941902687	0.388398510813636	0.842809416745795
GO:0008234	cysteine-type peptidase activity	16/1458	187/18639	0.0855614973262032	1.09381395655905	0.39195682051466	0.848853232593879
GO:0016829	lyase activity	17/1458	200/18639	0.085	1.08663580246914	0.397066497939598	0.856185785067393
GO:0004629	phospholipase C activity	3/1458	29/18639	0.103448275862069	1.32247765006386	0.398461690500399	0.856185785067393
GO:0043236	laminin binding	3/1458	29/18639	0.103448275862069	1.32247765006386	0.398461690500399	0.856185785067393
GO:0106222	lncRNA binding	3/1458	29/18639	0.103448275862069	1.32247765006386	0.398461690500399	0.856185785067393
GO:0038024	cargo receptor activity	6/1458	65/18639	0.0923076923076923	1.18005698005698	0.399385246005586	0.856404769212651
GO:0034212	protein N-acetyltransferase activity	5/1458	53/18639	0.0943396226415094	1.20603307710226	0.400723699757072	0.856404769212651
GO:0140318	protein transporter activity	4/1458	41/18639	0.0975609756097561	1.24721469436917	0.40090350762778	0.856404769212651
GO:0000900	mRNA regulatory element binding translation repressor activity	2/1458	18/18639	0.111111111111111	1.42043895747599	0.416671120088449	0.876790788528575
GO:0008308	voltage-gated monoatomic anion channel activity	2/1458	18/18639	0.111111111111111	1.42043895747599	0.416671120088449	0.876790788528575
GO:0015172	acidic amino acid transmembrane transporter activity	2/1458	18/18639	0.111111111111111	1.42043895747599	0.416671120088449	0.876790788528575
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/1458	18/18639	0.111111111111111	1.42043895747599	0.416671120088449	0.876790788528575
GO:0035615	clathrin adaptor activity	2/1458	18/18639	0.111111111111111	1.42043895747599	0.416671120088449	0.876790788528575
GO:0070064	proline-rich region binding	2/1458	18/18639	0.111111111111111	1.42043895747599	0.416671120088449	0.876790788528575
GO:1901611	phosphatidylglycerol binding	2/1458	18/18639	0.111111111111111	1.42043895747599	0.416671120088449	0.876790788528575
GO:0004520	DNA endonuclease activity	4/1458	42/18639	0.0952380952380952	1.217519106408	0.418991197878797	0.876790788528575
GO:0008187	poly-pyrimidine tract binding	3/1458	30/18639	0.1	1.2783950617284	0.420029102701303	0.876790788528575
GO:0031210	phosphatidylcholine binding	3/1458	30/18639	0.1	1.2783950617284	0.420029102701303	0.876790788528575
GO:0035925	mRNA 3'-UTR AU-rich region binding	3/1458	30/18639	0.1	1.2783950617284	0.420029102701303	0.876790788528575
GO:0070566	adenylyltransferase activity	3/1458	30/18639	0.1	1.2783950617284	0.420029102701303	0.876790788528575
GO:1990782	protein tyrosine kinase binding	10/1458	117/18639	0.0854700854700855	1.09264535190461	0.433415209937395	0.90279186176999
GO:0016874	ligase activity	14/1458	167/18639	0.0838323353293413	1.07170843498189	0.434129419867536	0.90279186176999
GO:0048306	calcium-dependent protein binding	7/1458	80/18639	0.0875	1.11859567901235	0.436729657451711	0.903341095897228
GO:0003777	microtubule motor activity	6/1458	68/18639	0.0882352941176471	1.12799564270153	0.442152440662692	0.903341095897228
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/1458	19/18639	0.105263157894737	1.34567901234568	0.444266112736342	0.903341095897228
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/1458	19/18639	0.105263157894737	1.34567901234568	0.444266112736342	0.903341095897228
GO:0005520	insulin-like growth factor binding	2/1458	19/18639	0.105263157894737	1.34567901234568	0.444266112736342	0.903341095897228
GO:0008381	mechanosensitive monoatomic ion channel activity	2/1458	19/18639	0.105263157894737	1.34567901234568	0.444266112736342	0.903341095897228
GO:0015245	fatty acid transmembrane transporter activity	2/1458	19/18639	0.105263157894737	1.34567901234568	0.444266112736342	0.903341095897228
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	2/1458	19/18639	0.105263157894737	1.34567901234568	0.444266112736342	0.903341095897228
GO:0031420	alkali metal ion binding	2/1458	19/18639	0.105263157894737	1.34567901234568	0.444266112736342	0.903341095897228
GO:0043395	heparan sulfate proteoglycan binding	2/1458	19/18639	0.105263157894737	1.34567901234568	0.444266112736342	0.903341095897228
GO:0097001	ceramide binding	2/1458	19/18639	0.105263157894737	1.34567901234568	0.444266112736342	0.903341095897228
GO:0120227	acyl-CoA binding	2/1458	19/18639	0.105263157894737	1.34567901234568	0.444266112736342	0.903341095897228
GO:0001223	transcription coactivator binding	4/1458	44/18639	0.0909090909090909	1.162177328844	0.454740817384067	0.921227707541891
GO:0030020	extracellular matrix structural constituent conferring tensile strength	4/1458	44/18639	0.0909090909090909	1.162177328844	0.454740817384067	0.921227707541891
GO:0043425	bHLH transcription factor binding	3/1458	32/18639	0.09375	1.19849537037037	0.46232005307105	0.929720546285739
GO:0071813	lipoprotein particle binding	3/1458	32/18639	0.09375	1.19849537037037	0.46232005307105	0.929720546285739
GO:0071814	protein-lipid complex binding	3/1458	32/18639	0.09375	1.19849537037037	0.46232005307105	0.929720546285739
GO:0140142	nucleocytoplasmic carrier activity	3/1458	32/18639	0.09375	1.19849537037037	0.46232005307105	0.929720546285739
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/1458	20/18639	0.1	1.2783950617284	0.471116478598497	0.940519806365728
GO:0030742	GTP-dependent protein binding	2/1458	20/18639	0.1	1.2783950617284	0.471116478598497	0.940519806365728
GO:0140664	ATP-dependent DNA damage sensor activity	2/1458	20/18639	0.1	1.2783950617284	0.471116478598497	0.940519806365728
GO:0140939	histone H4 methyltransferase activity	2/1458	20/18639	0.1	1.2783950617284	0.471116478598497	0.940519806365728
GO:0140416	transcription regulator inhibitor activity	3/1458	33/18639	0.0909090909090909	1.162177328844	0.482958397314424	0.962410744557601
GO:0030291	protein serine/threonine kinase inhibitor activity	4/1458	46/18639	0.0869565217391304	1.11164787976382	0.489728077275705	0.974133023276675
GO:0070888	E-box binding	5/1458	59/18639	0.0847457627118644	1.08338564553254	0.494456539762191	0.980058283383419
GO:0005123	death receptor binding	2/1458	21/18639	0.0952380952380952	1.217519106408	0.497169821352062	0.980058283383419
GO:0008373	sialyltransferase activity	2/1458	21/18639	0.0952380952380952	1.217519106408	0.497169821352062	0.980058283383419
GO:0051428	peptide hormone receptor binding	2/1458	21/18639	0.0952380952380952	1.217519106408	0.497169821352062	0.980058283383419
GO:0140312	cargo adaptor activity	2/1458	21/18639	0.0952380952380952	1.217519106408	0.497169821352062	0.980058283383419
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	3/1458	34/18639	0.0882352941176471	1.12799564270153	0.503210192590138	0.98754667964987
GO:0051427	hormone receptor binding	3/1458	34/18639	0.0882352941176471	1.12799564270153	0.503210192590138	0.98754667964987
GO:0042626	ATPase-coupled transmembrane transporter activity	8/1458	98/18639	0.0816326530612245	1.04358780549257	0.503666794721245	0.98754667964987
GO:0043495	protein-membrane adaptor activity	4/1458	47/18639	0.0851063829787234	1.08799579721566	0.506871500192885	0.990293429202468
GO:0061733	protein-lysine-acetyltransferase activity	4/1458	47/18639	0.0851063829787234	1.08799579721566	0.506871500192885	0.990293429202468
GO:0001098	basal transcription machinery binding	5/1458	60/18639	0.0833333333333333	1.065329218107	0.509590534829482	0.992075190146758
GO:0001099	basal RNA polymerase II transcription machinery binding	5/1458	60/18639	0.0833333333333333	1.065329218107	0.509590534829482	0.992075190146758
GO:0004407	histone deacetylase activity	2/1458	22/18639	0.0909090909090909	1.162177328844	0.522386484890224	0.999999999223096
GO:0033558	protein lysine deacetylase activity	2/1458	22/18639	0.0909090909090909	1.162177328844	0.522386484890224	0.999999999223096
GO:0048029	monosaccharide binding	6/1458	74/18639	0.0810810810810811	1.03653653653654	0.52536527458372	0.999999999223096
GO:0008081	phosphoric diester hydrolase activity	7/1458	87/18639	0.0804597701149425	1.02859372782744	0.526210148650336	0.999999999223096
GO:0005319	lipid transporter activity	14/1458	178/18639	0.0786516853932584	1.00547926203357	0.53192439876707	0.999999999223096
GO:0016763	pentosyltransferase activity	4/1458	49/18639	0.0816326530612245	1.04358780549257	0.54034897037339	0.999999999223096
GO:0005484	SNAP receptor activity	3/1458	36/18639	0.0833333333333333	1.065329218107	0.542436544267688	0.999999999223096
GO:0044390	ubiquitin-like protein conjugating enzyme binding	3/1458	36/18639	0.0833333333333333	1.065329218107	0.542436544267688	0.999999999223096
GO:0000295	adenine nucleotide transmembrane transporter activity	2/1458	23/18639	0.0869565217391304	1.11164787976382	0.546737883088811	0.999999999223096
GO:0003887	DNA-directed DNA polymerase activity	2/1458	23/18639	0.0869565217391304	1.11164787976382	0.546737883088811	0.999999999223096
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/1458	23/18639	0.0869565217391304	1.11164787976382	0.546737883088811	0.999999999223096
GO:0017134	fibroblast growth factor binding	2/1458	23/18639	0.0869565217391304	1.11164787976382	0.546737883088811	0.999999999223096
GO:0099186	structural constituent of postsynapse	2/1458	23/18639	0.0869565217391304	1.11164787976382	0.546737883088811	0.999999999223096
GO:0098631	cell adhesion mediator activity	6/1458	76/18639	0.0789473684210526	1.00925925925926	0.552001909369243	0.999999999223096
GO:0000182	rDNA binding	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0003796	lysozyme activity	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0005131	growth hormone receptor binding	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0005528	FK506 binding	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0008190	eukaryotic initiation factor 4E binding	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0008239	dipeptidyl-peptidase activity	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0015187	glycine transmembrane transporter activity	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0015279	store-operated calcium channel activity	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0016868	intramolecular phosphotransferase activity	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0031419	cobalamin binding	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0031434	mitogen-activated protein kinase kinase binding	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0032052	bile acid binding	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0042975	peroxisome proliferator activated receptor binding	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0043208	glycosphingolipid binding	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0043422	protein kinase B binding	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0070097	delta-catenin binding	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:1990757	ubiquitin ligase activator activity	1/1458	10/18639	0.1	1.2783950617284	0.557239075764802	0.999999999223096
GO:0022829	wide pore channel activity	3/1458	37/18639	0.0810810810810811	1.03653653653654	0.561362924624158	0.999999999223096
GO:0030280	structural constituent of skin epidermis	3/1458	37/18639	0.0810810810810811	1.03653653653654	0.561362924624158	0.999999999223096
GO:0004536	DNA nuclease activity	5/1458	64/18639	0.078125	0.998746141975309	0.568111313067569	0.999999999223096
GO:0005315	phosphate transmembrane transporter activity	2/1458	24/18639	0.0833333333333333	1.065329218107	0.570205012637728	0.999999999223096
GO:0005540	hyaluronic acid binding	2/1458	24/18639	0.0833333333333333	1.065329218107	0.570205012637728	0.999999999223096
GO:0015295	solute:proton symporter activity	2/1458	24/18639	0.0833333333333333	1.065329218107	0.570205012637728	0.999999999223096
GO:0030215	semaphorin receptor binding	2/1458	24/18639	0.0833333333333333	1.065329218107	0.570205012637728	0.999999999223096
GO:0030552	cAMP binding	2/1458	24/18639	0.0833333333333333	1.065329218107	0.570205012637728	0.999999999223096
GO:0070300	phosphatidic acid binding	2/1458	24/18639	0.0833333333333333	1.065329218107	0.570205012637728	0.999999999223096
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/1458	24/18639	0.0833333333333333	1.065329218107	0.570205012637728	0.999999999223096
GO:0000146	microfilament motor activity	3/1458	38/18639	0.0789473684210526	1.00925925925926	0.579805847546392	0.999999999223096
GO:0004016	adenylate cyclase activity	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0005114	type II transforming growth factor beta receptor binding	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0008271	secondary active sulfate transmembrane transporter activity	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0008503	benzodiazepine receptor activity	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0008526	phosphatidylinositol transfer activity	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0015173	aromatic amino acid transmembrane transporter activity	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0019215	intermediate filament binding	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0034056	estrogen response element binding	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0035252	UDP-xylosyltransferase activity	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0042285	xylosyltransferase activity	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0070697	activin receptor binding	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0097493	structural molecule activity conferring elasticity	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/1458	11/18639	0.0909090909090909	1.162177328844	0.591891790754062	0.999999999223096
GO:0008139	nuclear localization sequence binding	2/1458	25/18639	0.08	1.02271604938272	0.592777130547121	0.999999999223096
GO:0047617	fatty acyl-CoA hydrolase activity	2/1458	25/18639	0.08	1.02271604938272	0.592777130547121	0.999999999223096
GO:0008201	heparin binding	13/1458	172/18639	0.0755813953488372	0.96622882572495	0.592863444724218	0.999999999223096
GO:0000049	tRNA binding	6/1458	80/18639	0.075	0.958796296296296	0.603091406549808	0.999999999223096
GO:0050840	extracellular matrix binding	5/1458	67/18639	0.0746268656716418	0.954026165468951	0.60953361402683	0.999999999223096
GO:0030246	carbohydrate binding	21/1458	280/18639	0.075	0.958796296296296	0.612723905177805	0.999999999223096
GO:0004435	phosphatidylinositol phospholipase C activity	2/1458	26/18639	0.0769230769230769	0.98338081671415	0.614450579692105	0.999999999223096
GO:0005160	transforming growth factor beta receptor binding	2/1458	26/18639	0.0769230769230769	0.98338081671415	0.614450579692105	0.999999999223096
GO:0008143	poly(A) binding	2/1458	26/18639	0.0769230769230769	0.98338081671415	0.614450579692105	0.999999999223096
GO:0008157	protein phosphatase 1 binding	2/1458	26/18639	0.0769230769230769	0.98338081671415	0.614450579692105	0.999999999223096
GO:0015216	purine nucleotide transmembrane transporter activity	2/1458	26/18639	0.0769230769230769	0.98338081671415	0.614450579692105	0.999999999223096
GO:0016289	acyl-CoA hydrolase activity	2/1458	26/18639	0.0769230769230769	0.98338081671415	0.614450579692105	0.999999999223096
GO:0030247	polysaccharide binding	2/1458	26/18639	0.0769230769230769	0.98338081671415	0.614450579692105	0.999999999223096
GO:0070006	metalloaminopeptidase activity	2/1458	26/18639	0.0769230769230769	0.98338081671415	0.614450579692105	0.999999999223096
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	3/1458	40/18639	0.075	0.958796296296296	0.61518571037625	0.999999999223096
GO:0050997	quaternary ammonium group binding	3/1458	40/18639	0.075	0.958796296296296	0.61518571037625	0.999999999223096
GO:0071949	FAD binding	3/1458	40/18639	0.075	0.958796296296296	0.61518571037625	0.999999999223096
GO:0005548	phospholipid transporter activity	5/1458	68/18639	0.0735294117647059	0.939996368917938	0.622817834135095	0.999999999223096
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0004000	adenosine deaminase activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0004300	enoyl-CoA hydratase activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0005078	MAP-kinase scaffold activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0005095	GTPase inhibitor activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0005165	neurotrophin receptor binding	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0005527	macrolide binding	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0015368	calcium:monoatomic cation antiporter activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0016208	AMP binding	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0031543	peptidyl-proline dioxygenase activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0034452	dynactin binding	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0035251	UDP-glucosyltransferase activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0035497	cAMP response element binding	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0042301	phosphate ion binding	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0070008	serine-type exopeptidase activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:1990817	poly(A) RNA polymerase activity	1/1458	12/18639	0.0833333333333333	1.065329218107	0.623834123214905	0.999999999223096
GO:0001727	lipid kinase activity	3/1458	41/18639	0.0731707317073171	0.935411020776874	0.632102726382709	0.999999999223096
GO:0015175	neutral L-amino acid transmembrane transporter activity	3/1458	41/18639	0.0731707317073171	0.935411020776874	0.632102726382709	0.999999999223096
GO:0001671	ATPase activator activity	2/1458	27/18639	0.0740740740740741	0.946959304983996	0.635227747352328	0.999999999223096
GO:0004683	calcium/calmodulin-dependent protein kinase activity	2/1458	27/18639	0.0740740740740741	0.946959304983996	0.635227747352328	0.999999999223096
GO:0008266	poly(U) RNA binding	2/1458	27/18639	0.0740740740740741	0.946959304983996	0.635227747352328	0.999999999223096
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	2/1458	27/18639	0.0740740740740741	0.946959304983996	0.635227747352328	0.999999999223096
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	2/1458	27/18639	0.0740740740740741	0.946959304983996	0.635227747352328	0.999999999223096
GO:0008080	N-acetyltransferase activity	5/1458	69/18639	0.072463768115942	0.926373233136518	0.635827997012786	0.999999999223096
GO:0019894	kinesin binding	3/1458	42/18639	0.0714285714285714	0.913139329805997	0.64849592088301	0.999999999223096
GO:0035198	miRNA binding	3/1458	42/18639	0.0714285714285714	0.913139329805997	0.64849592088301	0.999999999223096
GO:0008028	monocarboxylic acid transmembrane transporter activity	5/1458	70/18639	0.0714285714285714	0.913139329805997	0.648558167345783	0.999999999223096
GO:0004527	exonuclease activity	6/1458	84/18639	0.0714285714285714	0.913139329805997	0.650844462706667	0.999999999223096
GO:0004535	poly(A)-specific ribonuclease activity	1/1458	13/18639	0.0769230769230769	0.98338081671415	0.653277933187132	0.999999999223096
GO:0008253	5'-nucleotidase activity	1/1458	13/18639	0.0769230769230769	0.98338081671415	0.653277933187132	0.999999999223096
GO:0017154	semaphorin receptor activity	1/1458	13/18639	0.0769230769230769	0.98338081671415	0.653277933187132	0.999999999223096
GO:0070700	BMP receptor binding	1/1458	13/18639	0.0769230769230769	0.98338081671415	0.653277933187132	0.999999999223096
GO:0089720	caspase binding	1/1458	13/18639	0.0769230769230769	0.98338081671415	0.653277933187132	0.999999999223096
GO:0097157	pre-mRNA intronic binding	1/1458	13/18639	0.0769230769230769	0.98338081671415	0.653277933187132	0.999999999223096
GO:0140333	glycerophospholipid flippase activity	1/1458	13/18639	0.0769230769230769	0.98338081671415	0.653277933187132	0.999999999223096
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/1458	13/18639	0.0769230769230769	0.98338081671415	0.653277933187132	0.999999999223096
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/1458	13/18639	0.0769230769230769	0.98338081671415	0.653277933187132	0.999999999223096
GO:0140852	histone ubiquitin ligase activity	1/1458	13/18639	0.0769230769230769	0.98338081671415	0.653277933187132	0.999999999223096
GO:0046966	nuclear thyroid hormone receptor binding	2/1458	28/18639	0.0714285714285714	0.913139329805997	0.655116143147901	0.999999999223096
GO:0050698	proteoglycan sulfotransferase activity	2/1458	28/18639	0.0714285714285714	0.913139329805997	0.655116143147901	0.999999999223096
GO:0141052	histone H3 demethylase activity	2/1458	28/18639	0.0714285714285714	0.913139329805997	0.655116143147901	0.999999999223096
GO:0005516	calmodulin binding	15/1458	207/18639	0.072463768115942	0.926373233136518	0.659402931193732	0.999999999223096
GO:0140299	molecular sensor activity	5/1458	71/18639	0.0704225352112676	0.900278212484785	0.661003373088957	0.999999999223096
GO:0008375	acetylglucosaminyltransferase activity	3/1458	43/18639	0.0697674418604651	0.891903531438415	0.664362068494472	0.999999999223096
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3/1458	43/18639	0.0697674418604651	0.891903531438415	0.664362068494472	0.999999999223096
GO:0046982	protein heterodimerization activity	27/1458	369/18639	0.0731707317073171	0.935411020776874	0.670688683809263	0.999999999223096
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	6/1458	86/18639	0.0697674418604651	0.891903531438415	0.673354334933989	0.999999999223096
GO:0035250	UDP-galactosyltransferase activity	2/1458	29/18639	0.0689655172413793	0.881651766709238	0.674127584084752	0.999999999223096
GO:0051861	glycolipid binding	2/1458	29/18639	0.0689655172413793	0.881651766709238	0.674127584084752	0.999999999223096
GO:0008408	3'-5' exonuclease activity	4/1458	58/18639	0.0689655172413793	0.881651766709238	0.674735717708075	0.999999999223096
GO:0016790	thiolester hydrolase activity	3/1458	44/18639	0.0681818181818182	0.871632996632997	0.679700208819623	0.999999999223096
GO:0043014	alpha-tubulin binding	3/1458	44/18639	0.0681818181818182	0.871632996632997	0.679700208819623	0.999999999223096
GO:0004705	JUN kinase activity	1/1458	14/18639	0.0714285714285714	0.913139329805997	0.680418530922188	0.999999999223096
GO:0005161	platelet-derived growth factor receptor binding	1/1458	14/18639	0.0714285714285714	0.913139329805997	0.680418530922188	0.999999999223096
GO:0005545	1-phosphatidylinositol binding	1/1458	14/18639	0.0714285714285714	0.913139329805997	0.680418530922188	0.999999999223096
GO:0008474	palmitoyl-(protein) hydrolase activity	1/1458	14/18639	0.0714285714285714	0.913139329805997	0.680418530922188	0.999999999223096
GO:0031404	chloride ion binding	1/1458	14/18639	0.0714285714285714	0.913139329805997	0.680418530922188	0.999999999223096
GO:0034236	protein kinase A catalytic subunit binding	1/1458	14/18639	0.0714285714285714	0.913139329805997	0.680418530922188	0.999999999223096
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/1458	14/18639	0.0714285714285714	0.913139329805997	0.680418530922188	0.999999999223096
GO:0044548	S100 protein binding	1/1458	14/18639	0.0714285714285714	0.913139329805997	0.680418530922188	0.999999999223096
GO:0046030	inositol trisphosphate phosphatase activity	1/1458	14/18639	0.0714285714285714	0.913139329805997	0.680418530922188	0.999999999223096
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/1458	14/18639	0.0714285714285714	0.913139329805997	0.680418530922188	0.999999999223096
GO:0061665	SUMO ligase activity	1/1458	14/18639	0.0714285714285714	0.913139329805997	0.680418530922188	0.999999999223096
GO:0061783	peptidoglycan muralytic activity	1/1458	14/18639	0.0714285714285714	0.913139329805997	0.680418530922188	0.999999999223096
GO:0071933	Arp2/3 complex binding	1/1458	14/18639	0.0714285714285714	0.913139329805997	0.680418530922188	0.999999999223096
GO:0098599	palmitoyl hydrolase activity	1/1458	14/18639	0.0714285714285714	0.913139329805997	0.680418530922188	0.999999999223096
GO:1901612	cardiolipin binding	1/1458	14/18639	0.0714285714285714	0.913139329805997	0.680418530922188	0.999999999223096
GO:0004521	RNA endonuclease activity	5/1458	73/18639	0.0684931506849315	0.875613055978353	0.685023551073469	0.999999999223096
GO:0001786	phosphatidylserine binding	4/1458	59/18639	0.0677966101694915	0.866708516426031	0.687846930649594	0.999999999223096
GO:0004879	nuclear receptor activity	4/1458	59/18639	0.0677966101694915	0.866708516426031	0.687846930649594	0.999999999223096
GO:0015459	potassium channel regulator activity	4/1458	59/18639	0.0677966101694915	0.866708516426031	0.687846930649594	0.999999999223096
GO:0031593	polyubiquitin modification-dependent protein binding	4/1458	59/18639	0.0677966101694915	0.866708516426031	0.687846930649594	0.999999999223096
GO:0001968	fibronectin binding	2/1458	30/18639	0.0666666666666667	0.852263374485597	0.692277475612142	0.999999999223096
GO:0015215	nucleotide transmembrane transporter activity	2/1458	30/18639	0.0666666666666667	0.852263374485597	0.692277475612142	0.999999999223096
GO:0032452	histone demethylase activity	2/1458	30/18639	0.0666666666666667	0.852263374485597	0.692277475612142	0.999999999223096
GO:0033612	receptor serine/threonine kinase binding	2/1458	30/18639	0.0666666666666667	0.852263374485597	0.692277475612142	0.999999999223096
GO:0048019	receptor antagonist activity	2/1458	30/18639	0.0666666666666667	0.852263374485597	0.692277475612142	0.999999999223096
GO:0051721	protein phosphatase 2A binding	2/1458	30/18639	0.0666666666666667	0.852263374485597	0.692277475612142	0.999999999223096
GO:0098918	structural constituent of synapse	2/1458	30/18639	0.0666666666666667	0.852263374485597	0.692277475612142	0.999999999223096
GO:0051539	4 iron, 4 sulfur cluster binding	3/1458	45/18639	0.0666666666666667	0.852263374485597	0.694511425234195	0.999999999223096
GO:0140303	intramembrane lipid transporter activity	3/1458	45/18639	0.0666666666666667	0.852263374485597	0.694511425234195	0.999999999223096
GO:0035064	methylated histone binding	5/1458	74/18639	0.0675675675675676	0.86378044711378	0.696592991398813	0.999999999223096
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	4/1458	60/18639	0.0666666666666667	0.852263374485597	0.70057953035103	0.999999999223096
GO:0098531	ligand-modulated transcription factor activity	4/1458	60/18639	0.0666666666666667	0.852263374485597	0.70057953035103	0.999999999223096
GO:0005041	low-density lipoprotein particle receptor activity	1/1458	15/18639	0.0666666666666667	0.852263374485597	0.70543596887738	0.999999999223096
GO:0008242	omega peptidase activity	1/1458	15/18639	0.0666666666666667	0.852263374485597	0.70543596887738	0.999999999223096
GO:0008252	nucleotidase activity	1/1458	15/18639	0.0666666666666667	0.852263374485597	0.70543596887738	0.999999999223096
GO:0010181	FMN binding	1/1458	15/18639	0.0666666666666667	0.852263374485597	0.70543596887738	0.999999999223096
GO:0015116	sulfate transmembrane transporter activity	1/1458	15/18639	0.0666666666666667	0.852263374485597	0.70543596887738	0.999999999223096
GO:0017081	chloride channel regulator activity	1/1458	15/18639	0.0666666666666667	0.852263374485597	0.70543596887738	0.999999999223096
GO:0042809	nuclear vitamin D receptor binding	1/1458	15/18639	0.0666666666666667	0.852263374485597	0.70543596887738	0.999999999223096
GO:0048531	beta-1,3-galactosyltransferase activity	1/1458	15/18639	0.0666666666666667	0.852263374485597	0.70543596887738	0.999999999223096
GO:0051371	muscle alpha-actinin binding	1/1458	15/18639	0.0666666666666667	0.852263374485597	0.70543596887738	0.999999999223096
GO:0061578	K63-linked deubiquitinase activity	1/1458	15/18639	0.0666666666666667	0.852263374485597	0.70543596887738	0.999999999223096
GO:0140776	protein-containing complex destabilizing activity	1/1458	15/18639	0.0666666666666667	0.852263374485597	0.70543596887738	0.999999999223096
GO:0004180	carboxypeptidase activity	3/1458	46/18639	0.0652173913043478	0.833735909822866	0.70879863555688	0.999999999223096
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3/1458	46/18639	0.0652173913043478	0.833735909822866	0.70879863555688	0.999999999223096
GO:0030276	clathrin binding	3/1458	46/18639	0.0652173913043478	0.833735909822866	0.70879863555688	0.999999999223096
GO:0047499	calcium-independent phospholipase A2 activity	2/1458	31/18639	0.0645161290322581	0.824771007566707	0.709584178674026	0.999999999223096
GO:0140457	protein demethylase activity	2/1458	31/18639	0.0645161290322581	0.824771007566707	0.709584178674026	0.999999999223096
GO:0019905	syntaxin binding	4/1458	61/18639	0.0655737704918033	0.838291843756325	0.712933363336608	0.999999999223096
GO:0005539	glycosaminoglycan binding	17/1458	242/18639	0.0702479338842975	0.898046117743088	0.713400983418318	0.999999999223096
GO:0140034	methylation-dependent protein binding	5/1458	76/18639	0.0657894736842105	0.841049382716049	0.718842678105216	0.999999999223096
GO:0015179	L-amino acid transmembrane transporter activity	4/1458	62/18639	0.0645161290322581	0.824771007566707	0.724909309300454	0.999999999223096
GO:0072341	modified amino acid binding	6/1458	91/18639	0.0659340659340659	0.842897842897843	0.72543046955658	0.999999999223096
GO:0008378	galactosyltransferase activity	2/1458	32/18639	0.0625	0.798996913580247	0.726068453714224	0.999999999223096
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/1458	32/18639	0.0625	0.798996913580247	0.726068453714224	0.999999999223096
GO:0047498	calcium-dependent phospholipase A2 activity	2/1458	32/18639	0.0625	0.798996913580247	0.726068453714224	0.999999999223096
GO:0070717	poly-purine tract binding	2/1458	32/18639	0.0625	0.798996913580247	0.726068453714224	0.999999999223096
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/1458	16/18639	0.0625	0.798996913580247	0.728496232911786	0.999999999223096
GO:0004707	MAP kinase activity	1/1458	16/18639	0.0625	0.798996913580247	0.728496232911786	0.999999999223096
GO:0005149	interleukin-1 receptor binding	1/1458	16/18639	0.0625	0.798996913580247	0.728496232911786	0.999999999223096
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/1458	16/18639	0.0625	0.798996913580247	0.728496232911786	0.999999999223096
GO:0005521	lamin binding	1/1458	16/18639	0.0625	0.798996913580247	0.728496232911786	0.999999999223096
GO:0008296	3'-5'-DNA exonuclease activity	1/1458	16/18639	0.0625	0.798996913580247	0.728496232911786	0.999999999223096
GO:0016722	oxidoreductase activity, acting on metal ions	1/1458	16/18639	0.0625	0.798996913580247	0.728496232911786	0.999999999223096
GO:0022858	alanine transmembrane transporter activity	1/1458	16/18639	0.0625	0.798996913580247	0.728496232911786	0.999999999223096
GO:0030275	LRR domain binding	1/1458	16/18639	0.0625	0.798996913580247	0.728496232911786	0.999999999223096
GO:0070411	I-SMAD binding	1/1458	16/18639	0.0625	0.798996913580247	0.728496232911786	0.999999999223096
GO:0140327	flippase activity	1/1458	16/18639	0.0625	0.798996913580247	0.728496232911786	0.999999999223096
GO:0140328	floppase activity	1/1458	16/18639	0.0625	0.798996913580247	0.728496232911786	0.999999999223096
GO:0015297	antiporter activity	9/1458	135/18639	0.0666666666666667	0.852263374485597	0.737917953619117	0.999999999223096
GO:1901681	sulfur compound binding	19/1458	275/18639	0.0690909090909091	0.883254769921437	0.746827637671899	0.999999999223096
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/1458	17/18639	0.0588235294117647	0.75199709513435	0.749752340542921	0.999999999223096
GO:0015278	intracellularly gated calcium channel activity	1/1458	17/18639	0.0588235294117647	0.75199709513435	0.749752340542921	0.999999999223096
GO:0017110	nucleoside diphosphate phosphatase activity	1/1458	17/18639	0.0588235294117647	0.75199709513435	0.749752340542921	0.999999999223096
GO:0019198	transmembrane receptor protein phosphatase activity	1/1458	17/18639	0.0588235294117647	0.75199709513435	0.749752340542921	0.999999999223096
GO:0030548	acetylcholine receptor regulator activity	1/1458	17/18639	0.0588235294117647	0.75199709513435	0.749752340542921	0.999999999223096
GO:0031489	myosin V binding	1/1458	17/18639	0.0588235294117647	0.75199709513435	0.749752340542921	0.999999999223096
GO:0032977	membrane insertase activity	1/1458	17/18639	0.0588235294117647	0.75199709513435	0.749752340542921	0.999999999223096
GO:0036041	long-chain fatty acid binding	1/1458	17/18639	0.0588235294117647	0.75199709513435	0.749752340542921	0.999999999223096
GO:0038191	neuropilin binding	1/1458	17/18639	0.0588235294117647	0.75199709513435	0.749752340542921	0.999999999223096
GO:0045236	CXCR chemokine receptor binding	1/1458	17/18639	0.0588235294117647	0.75199709513435	0.749752340542921	0.999999999223096
GO:0048038	quinone binding	1/1458	17/18639	0.0588235294117647	0.75199709513435	0.749752340542921	0.999999999223096
GO:0070402	NADPH binding	1/1458	17/18639	0.0588235294117647	0.75199709513435	0.749752340542921	0.999999999223096
GO:0070403	NAD+ binding	1/1458	17/18639	0.0588235294117647	0.75199709513435	0.749752340542921	0.999999999223096
GO:0070492	oligosaccharide binding	1/1458	17/18639	0.0588235294117647	0.75199709513435	0.749752340542921	0.999999999223096
GO:0008186	ATP-dependent activity, acting on RNA	5/1458	79/18639	0.0632911392405063	0.809110798562275	0.749991807882628	0.999999999223096
GO:0016410	N-acyltransferase activity	6/1458	94/18639	0.0638297872340425	0.815996847911742	0.753744143011839	0.999999999223096
GO:0042562	hormone binding	6/1458	94/18639	0.0638297872340425	0.815996847911742	0.753744143011839	0.999999999223096
GO:0016831	carboxy-lyase activity	2/1458	34/18639	0.0588235294117647	0.75199709513435	0.756661897287692	0.999999999223096
GO:0160215	deacylase activity	4/1458	65/18639	0.0615384615384615	0.78670465337132	0.758592371926236	0.999999999223096
GO:0070851	growth factor receptor binding	9/1458	139/18639	0.0647482014388489	0.827737809752198	0.76826632465161	0.999999999223096
GO:0008525	phosphatidylcholine transporter activity	1/1458	18/18639	0.0555555555555556	0.710219478737997	0.769345353510831	0.999999999223096
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/1458	18/18639	0.0555555555555556	0.710219478737997	0.769345353510831	0.999999999223096
GO:0017075	syntaxin-1 binding	1/1458	18/18639	0.0555555555555556	0.710219478737997	0.769345353510831	0.999999999223096
GO:0017128	phospholipid scramblase activity	1/1458	18/18639	0.0555555555555556	0.710219478737997	0.769345353510831	0.999999999223096
GO:0030228	lipoprotein particle receptor activity	1/1458	18/18639	0.0555555555555556	0.710219478737997	0.769345353510831	0.999999999223096
GO:0032393	MHC class I receptor activity	1/1458	18/18639	0.0555555555555556	0.710219478737997	0.769345353510831	0.999999999223096
GO:0098641	cadherin binding involved in cell-cell adhesion	1/1458	18/18639	0.0555555555555556	0.710219478737997	0.769345353510831	0.999999999223096
GO:0099602	neurotransmitter receptor regulator activity	1/1458	18/18639	0.0555555555555556	0.710219478737997	0.769345353510831	0.999999999223096
GO:0004623	phospholipase A2 activity	2/1458	35/18639	0.0571428571428571	0.730511463844797	0.770820500087064	0.999999999223096
GO:0016229	steroid dehydrogenase activity	2/1458	35/18639	0.0571428571428571	0.730511463844797	0.770820500087064	0.999999999223096
GO:0034061	DNA polymerase activity	2/1458	35/18639	0.0571428571428571	0.730511463844797	0.770820500087064	0.999999999223096
GO:0043015	gamma-tubulin binding	2/1458	35/18639	0.0571428571428571	0.730511463844797	0.770820500087064	0.999999999223096
GO:0016407	acetyltransferase activity	6/1458	96/18639	0.0625	0.798996913580247	0.771400326089953	0.999999999223096
GO:0016830	carbon-carbon lyase activity	3/1458	51/18639	0.0588235294117647	0.75199709513435	0.772581287028346	0.999999999223096
GO:1902936	phosphatidylinositol bisphosphate binding	7/1458	111/18639	0.0630630630630631	0.806195083972862	0.774571263438056	0.999999999223096
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	4/1458	67/18639	0.0597014925373134	0.763220932375161	0.779213487376689	0.999999999223096
GO:0045505	dynein intermediate chain binding	2/1458	36/18639	0.0555555555555556	0.710219478737997	0.78425485042938	0.999999999223096
GO:0042826	histone deacetylase binding	8/1458	127/18639	0.062992125984252	0.805288227860406	0.785663026467453	0.999999999223096
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/1458	19/18639	0.0526315789473684	0.672839506172839	0.787405311331636	0.999999999223096
GO:0030506	ankyrin binding	1/1458	19/18639	0.0526315789473684	0.672839506172839	0.787405311331636	0.999999999223096
GO:0046527	glucosyltransferase activity	1/1458	19/18639	0.0526315789473684	0.672839506172839	0.787405311331636	0.999999999223096
GO:0046624	sphingolipid transporter activity	1/1458	19/18639	0.0526315789473684	0.672839506172839	0.787405311331636	0.999999999223096
GO:0140036	ubiquitin-modified protein reader activity	1/1458	19/18639	0.0526315789473684	0.672839506172839	0.787405311331636	0.999999999223096
GO:0030165	PDZ domain binding	5/1458	83/18639	0.0602409638554217	0.770117507065298	0.787426443063787	0.999999999223096
GO:0140223	general transcription initiation factor activity	4/1458	68/18639	0.0588235294117647	0.75199709513435	0.788988215704289	0.999999999223096
GO:0005544	calcium-dependent phospholipid binding	3/1458	53/18639	0.0566037735849057	0.723619846261356	0.794681671977308	0.999999999223096
GO:0016251	RNA polymerase II general transcription initiation factor activity	3/1458	53/18639	0.0566037735849057	0.723619846261356	0.794681671977308	0.999999999223096
GO:0051018	protein kinase A binding	3/1458	53/18639	0.0566037735849057	0.723619846261356	0.794681671977308	0.999999999223096
GO:0019213	deacetylase activity	2/1458	37/18639	0.0540540540540541	0.691024357691024	0.796991531903964	0.999999999223096
GO:0030551	cyclic nucleotide binding	2/1458	37/18639	0.0540540540540541	0.691024357691024	0.796991531903964	0.999999999223096
GO:0042805	actinin binding	2/1458	37/18639	0.0540540540540541	0.691024357691024	0.796991531903964	0.999999999223096
GO:0002039	p53 binding	4/1458	69/18639	0.0579710144927536	0.741098586509215	0.798413459931458	0.999999999223096
GO:0031406	carboxylic acid binding	12/1458	187/18639	0.0641711229946524	0.820360467419291	0.801404783978811	0.999999999223096
GO:0140030	modification-dependent protein binding	11/1458	173/18639	0.0635838150289017	0.812852351387997	0.803266716809094	0.999999999223096
GO:0000339	RNA cap binding	1/1458	20/18639	0.05	0.639197530864198	0.804052092001801	0.999999999223096
GO:0001972	retinoic acid binding	1/1458	20/18639	0.05	0.639197530864198	0.804052092001801	0.999999999223096
GO:0016408	C-acyltransferase activity	1/1458	20/18639	0.05	0.639197530864198	0.804052092001801	0.999999999223096
GO:0030627	pre-mRNA 5'-splice site binding	1/1458	20/18639	0.05	0.639197530864198	0.804052092001801	0.999999999223096
GO:0052745	inositol phosphate phosphatase activity	1/1458	20/18639	0.05	0.639197530864198	0.804052092001801	0.999999999223096
GO:0061608	nuclear import signal receptor activity	1/1458	20/18639	0.05	0.639197530864198	0.804052092001801	0.999999999223096
GO:0005501	retinoid binding	2/1458	38/18639	0.0526315789473684	0.672839506172839	0.809057403257163	0.999999999223096
GO:0019840	isoprenoid binding	2/1458	38/18639	0.0526315789473684	0.672839506172839	0.809057403257163	0.999999999223096
GO:0043177	organic acid binding	12/1458	189/18639	0.0634920634920635	0.811679404271997	0.81262840699904	0.999999999223096
GO:0098632	cell-cell adhesion mediator activity	3/1458	55/18639	0.0545454545454545	0.697306397306397	0.814959336479133	0.999999999223096
GO:0035402	histone H3T11 kinase activity	16/1458	247/18639	0.0647773279352227	0.828110161443495	0.817755850935974	0.999999999223096
GO:0035403	histone H3T6 kinase activity	16/1458	247/18639	0.0647773279352227	0.828110161443495	0.817755850935974	0.999999999223096
GO:0008238	exopeptidase activity	6/1458	102/18639	0.0588235294117647	0.75199709513435	0.818662679705849	0.999999999223096
GO:0005248	voltage-gated sodium channel activity	1/1458	21/18639	0.0476190476190476	0.608759553203998	0.819396205534288	0.999999999223096
GO:0009975	cyclase activity	1/1458	21/18639	0.0476190476190476	0.608759553203998	0.819396205534288	0.999999999223096
GO:0010314	phosphatidylinositol-5-phosphate binding	1/1458	21/18639	0.0476190476190476	0.608759553203998	0.819396205534288	0.999999999223096
GO:0019200	carbohydrate kinase activity	1/1458	21/18639	0.0476190476190476	0.608759553203998	0.819396205534288	0.999999999223096
GO:1904047	S-adenosyl-L-methionine binding	1/1458	21/18639	0.0476190476190476	0.608759553203998	0.819396205534288	0.999999999223096
GO:0004177	aminopeptidase activity	2/1458	40/18639	0.05	0.639197530864198	0.831284323497209	0.999999999223096
GO:0032451	demethylase activity	2/1458	40/18639	0.05	0.639197530864198	0.831284323497209	0.999999999223096
GO:0071855	neuropeptide receptor binding	2/1458	40/18639	0.05	0.639197530864198	0.831284323497209	0.999999999223096
GO:0008093	cytoskeletal anchor activity	1/1458	22/18639	0.0454545454545455	0.581088664421998	0.833539525564957	0.999999999223096
GO:0008649	rRNA methyltransferase activity	1/1458	22/18639	0.0454545454545455	0.581088664421998	0.833539525564957	0.999999999223096
GO:0008970	phospholipase A1 activity	1/1458	22/18639	0.0454545454545455	0.581088664421998	0.833539525564957	0.999999999223096
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/1458	22/18639	0.0454545454545455	0.581088664421998	0.833539525564957	0.999999999223096
GO:0016881	acid-amino acid ligase activity	1/1458	22/18639	0.0454545454545455	0.581088664421998	0.833539525564957	0.999999999223096
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/1458	22/18639	0.0454545454545455	0.581088664421998	0.833539525564957	0.999999999223096
GO:0033691	sialic acid binding	1/1458	22/18639	0.0454545454545455	0.581088664421998	0.833539525564957	0.999999999223096
GO:0050321	tau-protein kinase activity	1/1458	22/18639	0.0454545454545455	0.581088664421998	0.833539525564957	0.999999999223096
GO:0140035	ubiquitin-like protein reader activity	1/1458	22/18639	0.0454545454545455	0.581088664421998	0.833539525564957	0.999999999223096
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	2/1458	41/18639	0.0487804878048781	0.623607347184583	0.841498764374876	0.999999999223096
GO:0017080	sodium channel regulator activity	2/1458	41/18639	0.0487804878048781	0.623607347184583	0.841498764374876	0.999999999223096
GO:0061980	regulatory RNA binding	3/1458	58/18639	0.0517241379310345	0.661238825031929	0.842171764214165	0.999999999223096
GO:0000149	SNARE binding	6/1458	106/18639	0.0566037735849057	0.723619846261356	0.845637409287493	0.999999999223096
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/1458	23/18639	0.0434782608695652	0.555823939881911	0.846575963859328	0.999999999223096
GO:0005158	insulin receptor binding	1/1458	23/18639	0.0434782608695652	0.555823939881911	0.846575963859328	0.999999999223096
GO:0005212	structural constituent of eye lens	1/1458	23/18639	0.0434782608695652	0.555823939881911	0.846575963859328	0.999999999223096
GO:0005283	amino acid:sodium symporter activity	1/1458	23/18639	0.0434782608695652	0.555823939881911	0.846575963859328	0.999999999223096
GO:0016849	phosphorus-oxygen lyase activity	1/1458	23/18639	0.0434782608695652	0.555823939881911	0.846575963859328	0.999999999223096
GO:0070577	lysine-acetylated histone binding	1/1458	23/18639	0.0434782608695652	0.555823939881911	0.846575963859328	0.999999999223096
GO:0140102	catalytic activity, acting on a rRNA	1/1458	23/18639	0.0434782608695652	0.555823939881911	0.846575963859328	0.999999999223096
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/1458	23/18639	0.0434782608695652	0.555823939881911	0.846575963859328	0.999999999223096
GO:0004402	histone acetyltransferase activity	2/1458	42/18639	0.0476190476190476	0.608759553203998	0.851148906549469	0.999999999223096
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	3/1458	60/18639	0.05	0.639197530864198	0.858326515257596	0.999999999223096
GO:0015149	hexose transmembrane transporter activity	1/1458	24/18639	0.0416666666666667	0.532664609053498	0.85859209217331	0.999999999223096
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/1458	24/18639	0.0416666666666667	0.532664609053498	0.85859209217331	0.999999999223096
GO:0055056	D-glucose transmembrane transporter activity	1/1458	24/18639	0.0416666666666667	0.532664609053498	0.85859209217331	0.999999999223096
GO:0140033	acetylation-dependent protein binding	1/1458	24/18639	0.0416666666666667	0.532664609053498	0.85859209217331	0.999999999223096
GO:0005543	phospholipid binding	33/1458	497/18639	0.0663983903420523	0.848833743199941	0.860949558435993	0.999999999223096
GO:0003724	RNA helicase activity	4/1458	77/18639	0.051948051948052	0.664101330767997	0.862068861031648	0.999999999223096
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	15/1458	243/18639	0.0617283950617284	0.78913275415333	0.862657920309463	0.999999999223096
GO:1901981	phosphatidylinositol phosphate binding	11/1458	185/18639	0.0594594594594595	0.760126793460127	0.865106308969068	0.999999999223096
GO:0016836	hydro-lyase activity	3/1458	61/18639	0.0491803278688525	0.628718882817244	0.865846850701785	0.999999999223096
GO:0003707	nuclear steroid receptor activity	1/1458	25/18639	0.04	0.511358024691358	0.869667715574402	0.999999999223096
GO:0005537	D-mannose binding	1/1458	25/18639	0.04	0.511358024691358	0.869667715574402	0.999999999223096
GO:0015662	P-type ion transporter activity	1/1458	25/18639	0.04	0.511358024691358	0.869667715574402	0.999999999223096
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/1458	25/18639	0.04	0.511358024691358	0.869667715574402	0.999999999223096
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	1/1458	25/18639	0.04	0.511358024691358	0.869667715574402	0.999999999223096
GO:0140358	P-type transmembrane transporter activity	1/1458	25/18639	0.04	0.511358024691358	0.869667715574402	0.999999999223096
GO:0004676	3-phosphoinositide-dependent protein kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0004711	ribosomal protein S6 kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0035175	histone H3S10 kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0035979	histone H2AXS139 kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0044022	histone H3S28 kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0044023	histone H4S1 kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0044024	histone H2AS1 kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0044025	histone H2BS14 kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0072354	histone H3T3 kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0072371	histone H2AS121 kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0072518	Rho-dependent protein serine/threonine kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0140823	histone H2BS36 kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0140855	histone H3S57 kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0140995	histone H2A kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0140997	histone H4 kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0140998	histone H2B kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:1990244	histone H2AT120 kinase activity	15/1458	245/18639	0.0612244897959184	0.782690854119426	0.87037402935071	0.999999999223096
GO:0004867	serine-type endopeptidase inhibitor activity	5/1458	95/18639	0.0526315789473684	0.672839506172839	0.873815193963763	0.999999999223096
GO:0008276	protein methyltransferase activity	5/1458	95/18639	0.0526315789473684	0.672839506172839	0.873815193963763	0.999999999223096
GO:0004677	DNA-dependent protein kinase activity	15/1458	246/18639	0.0609756097560976	0.779509183980729	0.874102282905711	0.999999999223096
GO:0140857	histone H3T45 kinase activity	15/1458	246/18639	0.0609756097560976	0.779509183980729	0.874102282905711	0.999999999223096
GO:0004519	endonuclease activity	7/1458	127/18639	0.0551181102362205	0.704627199377855	0.876707185815507	0.999999999223096
GO:0005227	calcium-activated cation channel activity	1/1458	26/18639	0.0384615384615385	0.491690408357075	0.879876401009693	0.999999999223096
GO:0015145	monosaccharide transmembrane transporter activity	1/1458	26/18639	0.0384615384615385	0.491690408357075	0.879876401009693	0.999999999223096
GO:0030507	spectrin binding	1/1458	26/18639	0.0384615384615385	0.491690408357075	0.879876401009693	0.999999999223096
GO:0034237	protein kinase A regulatory subunit binding	1/1458	26/18639	0.0384615384615385	0.491690408357075	0.879876401009693	0.999999999223096
GO:0051139	metal cation:proton antiporter activity	1/1458	26/18639	0.0384615384615385	0.491690408357075	0.879876401009693	0.999999999223096
GO:0004679	AMP-activated protein kinase activity	15/1458	248/18639	0.0604838709677419	0.773222819593787	0.881304353644269	0.999999999223096
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	1/1458	27/18639	0.037037037037037	0.473479652491998	0.8892859646119	0.999999999223096
GO:0016798	hydrolase activity, acting on glycosyl bonds	7/1458	130/18639	0.0538461538461538	0.688366571699905	0.890791836368593	0.999999999223096
GO:0140938	histone H3 methyltransferase activity	2/1458	47/18639	0.0425531914893617	0.543997898607828	0.89181380360705	0.999999999223096
GO:0008083	growth factor activity	9/1458	162/18639	0.0555555555555556	0.710219478737997	0.894948631716797	0.999999999223096
GO:0016866	intramolecular transferase activity	1/1458	28/18639	0.0357142857142857	0.456569664902998	0.897958920962418	0.999999999223096
GO:0045499	chemorepellent activity	1/1458	28/18639	0.0357142857142857	0.456569664902998	0.897958920962418	0.999999999223096
GO:0051119	sugar transmembrane transporter activity	1/1458	28/18639	0.0357142857142857	0.456569664902998	0.897958920962418	0.999999999223096
GO:0051393	alpha-actinin binding	1/1458	28/18639	0.0357142857142857	0.456569664902998	0.897958920962418	0.999999999223096
GO:0051959	dynein light intermediate chain binding	1/1458	28/18639	0.0357142857142857	0.456569664902998	0.897958920962418	0.999999999223096
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	1/1458	28/18639	0.0357142857142857	0.456569664902998	0.897958920962418	0.999999999223096
GO:0016879	ligase activity, forming carbon-nitrogen bonds	2/1458	48/18639	0.0416666666666667	0.532664609053498	0.898596112027579	0.999999999223096
GO:0032266	phosphatidylinositol-3-phosphate binding	2/1458	48/18639	0.0416666666666667	0.532664609053498	0.898596112027579	0.999999999223096
GO:0005261	monoatomic cation channel activity	21/1458	341/18639	0.06158357771261	0.787281416313674	0.899019623928468	0.999999999223096
GO:0042054	histone methyltransferase activity	3/1458	67/18639	0.0447761194029851	0.572415699281371	0.903980672600181	0.999999999223096
GO:0005416	amino acid:monoatomic cation symporter activity	1/1458	29/18639	0.0344827586206897	0.440825883354619	0.905952897279478	0.999999999223096
GO:0010484	histone H3 acetyltransferase activity	1/1458	29/18639	0.0344827586206897	0.440825883354619	0.905952897279478	0.999999999223096
GO:0099604	ligand-gated calcium channel activity	1/1458	29/18639	0.0344827586206897	0.440825883354619	0.905952897279478	0.999999999223096
GO:0015605	organophosphate ester transmembrane transporter activity	2/1458	50/18639	0.04	0.511358024691358	0.910986957670183	0.999999999223096
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/1458	30/18639	0.0333333333333333	0.426131687242798	0.913321015268007	0.999999999223096
GO:0016769	transferase activity, transferring nitrogenous groups	1/1458	30/18639	0.0333333333333333	0.426131687242798	0.913321015268007	0.999999999223096
GO:0022839	monoatomic ion-gated channel activity	1/1458	30/18639	0.0333333333333333	0.426131687242798	0.913321015268007	0.999999999223096
GO:0031624	ubiquitin conjugating enzyme binding	1/1458	30/18639	0.0333333333333333	0.426131687242798	0.913321015268007	0.999999999223096
GO:0005216	monoatomic ion channel activity	28/1458	448/18639	0.0625	0.798996913580247	0.914032217728349	0.999999999223096
GO:0004175	endopeptidase activity	25/1458	405/18639	0.0617283950617284	0.78913275415333	0.914231771287022	0.999999999223096
GO:0016782	transferase activity, transferring sulphur-containing groups	3/1458	70/18639	0.0428571428571429	0.547883597883598	0.919111299369061	0.999999999223096
GO:0004540	RNA nuclease activity	6/1458	121/18639	0.0495867768595041	0.633914906642179	0.919124625484616	0.999999999223096
GO:0005452	solute:inorganic anion antiporter activity	1/1458	31/18639	0.032258064516129	0.412385503783353	0.920112243154473	0.999999999223096
GO:0070273	phosphatidylinositol-4-phosphate binding	1/1458	31/18639	0.032258064516129	0.412385503783353	0.920112243154473	0.999999999223096
GO:0005506	iron ion binding	8/1458	154/18639	0.051948051948052	0.664101330767997	0.921918595578032	0.999999999223096
GO:0003730	mRNA 3'-UTR binding	15/1458	262/18639	0.0572519083969466	0.731905569691829	0.922937962522684	0.999999999223096
GO:0015106	bicarbonate transmembrane transporter activity	1/1458	32/18639	0.03125	0.399498456790123	0.92637172023319	0.999999999223096
GO:0042910	xenobiotic transmembrane transporter activity	1/1458	32/18639	0.03125	0.399498456790123	0.92637172023319	0.999999999223096
GO:0008146	sulfotransferase activity	2/1458	53/18639	0.0377358490566038	0.482413230840904	0.926937808215316	0.999999999223096
GO:0017046	peptide hormone binding	2/1458	53/18639	0.0377358490566038	0.482413230840904	0.926937808215316	0.999999999223096
GO:1901505	carbohydrate derivative transmembrane transporter activity	2/1458	53/18639	0.0377358490566038	0.482413230840904	0.926937808215316	0.999999999223096
GO:0046943	carboxylic acid transmembrane transporter activity	10/1458	188/18639	0.0531914893617021	0.679997373259785	0.929246513231061	0.999999999223096
GO:0050661	NADP binding	2/1458	54/18639	0.037037037037037	0.473479652491998	0.931626092229249	0.999999999223096
GO:0140463	chromatin-protein adaptor activity	2/1458	54/18639	0.037037037037037	0.473479652491998	0.931626092229249	0.999999999223096
GO:0005342	organic acid transmembrane transporter activity	10/1458	189/18639	0.0529100529100529	0.676399503559997	0.93189140721009	0.999999999223096
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/1458	33/18639	0.0303030303030303	0.387392442947999	0.932141056069167	0.999999999223096
GO:0030296	protein tyrosine kinase activator activity	1/1458	33/18639	0.0303030303030303	0.387392442947999	0.932141056069167	0.999999999223096
GO:0042923	neuropeptide binding	1/1458	33/18639	0.0303030303030303	0.387392442947999	0.932141056069167	0.999999999223096
GO:0004620	phospholipase activity	5/1458	109/18639	0.0458715596330275	0.58641975308642	0.93511325719543	0.999999999223096
GO:0008376	acetylgalactosaminyltransferase activity	1/1458	34/18639	0.0294117647058824	0.375998547567175	0.937458606335272	0.999999999223096
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/1458	34/18639	0.0294117647058824	0.375998547567175	0.937458606335272	0.999999999223096
GO:0052866	phosphatidylinositol phosphate phosphatase activity	1/1458	34/18639	0.0294117647058824	0.375998547567175	0.937458606335272	0.999999999223096
GO:0090482	vitamin transmembrane transporter activity	1/1458	34/18639	0.0294117647058824	0.375998547567175	0.937458606335272	0.999999999223096
GO:0051213	dioxygenase activity	4/1458	93/18639	0.043010752688172	0.549847338377804	0.939387108936485	0.999999999223096
GO:0001216	DNA-binding transcription activator activity	30/1458	491/18639	0.0610997963340122	0.781096779060119	0.939593712391066	0.999999999223096
GO:0030170	pyridoxal phosphate binding	2/1458	56/18639	0.0357142857142857	0.456569664902998	0.940161347039383	0.999999999223096
GO:0170055	lipid transmembrane transporter activity	2/1458	56/18639	0.0357142857142857	0.456569664902998	0.940161347039383	0.999999999223096
GO:0000175	3'-5'-RNA exonuclease activity	1/1458	35/18639	0.0285714285714286	0.365255731922399	0.942359727107278	0.999999999223096
GO:0005154	epidermal growth factor receptor binding	1/1458	35/18639	0.0285714285714286	0.365255731922399	0.942359727107278	0.999999999223096
GO:0005343	organic acid:sodium symporter activity	1/1458	35/18639	0.0285714285714286	0.365255731922399	0.942359727107278	0.999999999223096
GO:0010485	histone H4 acetyltransferase activity	1/1458	35/18639	0.0285714285714286	0.365255731922399	0.942359727107278	0.999999999223096
GO:0140566	histone reader activity	1/1458	35/18639	0.0285714285714286	0.365255731922399	0.942359727107278	0.999999999223096
GO:0008194	UDP-glycosyltransferase activity	7/1458	145/18639	0.0482758620689655	0.617156236696467	0.942448671469417	0.999999999223096
GO:0019787	ubiquitin-like protein transferase activity	29/1458	479/18639	0.0605427974947808	0.7739761334055	0.943317065362497	0.999999999223096
GO:0015932	nucleobase-containing compound transmembrane transporter activity	2/1458	57/18639	0.0350877192982456	0.448559670781893	0.944039531329904	0.999999999223096
GO:0070279	vitamin B6 binding	2/1458	57/18639	0.0350877192982456	0.448559670781893	0.944039531329904	0.999999999223096
GO:0000993	RNA polymerase II complex binding	1/1458	36/18639	0.0277777777777778	0.355109739368999	0.946877009298075	0.999999999223096
GO:0004190	aspartic-type endopeptidase activity	1/1458	36/18639	0.0277777777777778	0.355109739368999	0.946877009298075	0.999999999223096
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	29/1458	484/18639	0.0599173553719008	0.765980512192633	0.950254513107331	0.999999999223096
GO:0070001	aspartic-type peptidase activity	1/1458	37/18639	0.027027027027027	0.345512178845512	0.951040494781245	0.999999999223096
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	2/1458	60/18639	0.0333333333333333	0.426131687242798	0.95428826815429	0.999999999223096
GO:0005109	frizzled binding	1/1458	38/18639	0.0263157894736842	0.33641975308642	0.954877875633247	0.999999999223096
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/1458	38/18639	0.0263157894736842	0.33641975308642	0.954877875633247	0.999999999223096
GO:0005201	extracellular matrix structural constituent	8/1458	168/18639	0.0476190476190476	0.608759553203998	0.956815251745231	0.999999999223096
GO:0015101	organic cation transmembrane transporter activity	3/1458	81/18639	0.037037037037037	0.473479652491998	0.957757828076199	0.999999999223096
GO:0004532	RNA exonuclease activity	1/1458	40/18639	0.025	0.319598765432099	0.961674430486724	0.999999999223096
GO:0015144	carbohydrate transmembrane transporter activity	1/1458	40/18639	0.025	0.319598765432099	0.961674430486724	0.999999999223096
GO:0015171	amino acid transmembrane transporter activity	4/1458	102/18639	0.0392156862745098	0.501331396756233	0.962974338649605	0.999999999223096
GO:0016755	aminoacyltransferase activity	29/1458	496/18639	0.0584677419354839	0.747448725607328	0.964020912979456	0.999999999223096
GO:0008514	organic anion transmembrane transporter activity	14/1458	269/18639	0.0520446096654275	0.665335719858644	0.964198449690968	0.999999999223096
GO:0140828	metal cation:monoatomic cation antiporter activity	1/1458	41/18639	0.024390243902439	0.311803673592291	0.96467882213952	0.999999999223096
GO:0005253	monoatomic anion channel activity	4/1458	103/18639	0.0388349514563107	0.496464101642095	0.964988263596995	0.999999999223096
GO:0008307	structural constituent of muscle	1/1458	42/18639	0.0238095238095238	0.304379776601999	0.967447844470985	0.999999999223096
GO:0043175	RNA polymerase core enzyme binding	1/1458	42/18639	0.0238095238095238	0.304379776601999	0.967447844470985	0.999999999223096
GO:0050660	flavin adenine dinucleotide binding	3/1458	86/18639	0.0348837209302326	0.445951765719208	0.968856066902902	0.999999999223096
GO:0004518	nuclease activity	10/1458	209/18639	0.0478468899521531	0.611672278338945	0.969462333378242	0.999999999223096
GO:0008235	metalloexopeptidase activity	2/1458	66/18639	0.0303030303030303	0.387392442947999	0.969657642097593	0.999999999223096
GO:0004252	serine-type endopeptidase activity	8/1458	176/18639	0.0454545454545455	0.581088664421998	0.969762481108939	0.999999999223096
GO:0008013	beta-catenin binding	4/1458	106/18639	0.0377358490566038	0.482413230840904	0.970434737642055	0.999999999223096
GO:0008236	serine-type peptidase activity	9/1458	194/18639	0.0463917525773196	0.593069873997709	0.971392704876656	0.999999999223096
GO:0004843	cysteine-type deubiquitinase activity	4/1458	108/18639	0.037037037037037	0.473479652491998	0.973614141258083	0.999999999223096
GO:0019783	ubiquitin-like protein peptidase activity	5/1458	127/18639	0.0393700787401575	0.503305142412754	0.97433076625711	0.999999999223096
GO:0004842	ubiquitin-protein transferase activity	25/1458	449/18639	0.0556792873051225	0.711801259314251	0.975145911518186	0.999999999223096
GO:0016279	protein-lysine N-methyltransferase activity	2/1458	69/18639	0.0289855072463768	0.370549293254607	0.975337489466318	0.999999999223096
GO:0015293	symporter activity	6/1458	146/18639	0.0410958904109589	0.525367833587012	0.975677243187804	0.999999999223096
GO:0017171	serine hydrolase activity	9/1458	198/18639	0.0454545454545455	0.581088664421998	0.976019106760794	0.999999999223096
GO:0016741	transferase activity, transferring one-carbon groups	10/1458	215/18639	0.0465116279069767	0.594602354292277	0.976325903808307	0.999999999223096
GO:0015085	calcium ion transmembrane transporter activity	6/1458	147/18639	0.0408163265306122	0.521793902746284	0.976881792963255	0.999999999223096
GO:0016278	lysine N-methyltransferase activity	2/1458	70/18639	0.0285714285714286	0.365255731922399	0.976991200939767	0.999999999223096
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	3/1458	91/18639	0.032967032967033	0.421448921448921	0.977156583081842	0.999999999223096
GO:0016298	lipase activity	5/1458	130/18639	0.0384615384615385	0.491690408357075	0.978153791020906	0.999999999223096
GO:0140359	ABC-type transporter activity	1/1458	47/18639	0.0212765957446809	0.271998949303914	0.978359224440607	0.999999999223096
GO:0052689	carboxylic ester hydrolase activity	3/1458	92/18639	0.0326086956521739	0.416867954911433	0.978542065310765	0.999999999223096
GO:0016757	glycosyltransferase activity	13/1458	267/18639	0.048689138576779	0.622439543163638	0.978941969074266	0.999999999223096
GO:0008509	monoatomic anion transmembrane transporter activity	6/1458	149/18639	0.0402684563758389	0.514789957742978	0.979126688579061	0.999999999223096
GO:0005262	calcium channel activity	5/1458	131/18639	0.0381679389312977	0.487937046461219	0.979305126956514	0.999999999223096
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	7/1458	167/18639	0.0419161676646707	0.535854217490944	0.979427038015462	0.999999999223096
GO:0035091	phosphatidylinositol binding	14/1458	284/18639	0.0492957746478873	0.63019474873935	0.979640380828055	0.999999999223096
GO:0008188	neuropeptide receptor activity	1/1458	48/18639	0.0208333333333333	0.266332304526749	0.980056311938756	0.999999999223096
GO:0005004	GPI-linked ephrin receptor activity	1/1458	49/18639	0.0204081632653061	0.260896951373142	0.981620396559986	0.999999999223096
GO:0005008	hepatocyte growth factor receptor activity	1/1458	49/18639	0.0204081632653061	0.260896951373142	0.981620396559986	0.999999999223096
GO:0005009	insulin receptor activity	1/1458	49/18639	0.0204081632653061	0.260896951373142	0.981620396559986	0.999999999223096
GO:0005011	macrophage colony-stimulating factor receptor activity	1/1458	49/18639	0.0204081632653061	0.260896951373142	0.981620396559986	0.999999999223096
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/1458	49/18639	0.0204081632653061	0.260896951373142	0.981620396559986	0.999999999223096
GO:0005020	stem cell factor receptor activity	1/1458	49/18639	0.0204081632653061	0.260896951373142	0.981620396559986	0.999999999223096
GO:0008288	boss receptor activity	1/1458	49/18639	0.0204081632653061	0.260896951373142	0.981620396559986	0.999999999223096
GO:0036332	placental growth factor receptor activity	1/1458	49/18639	0.0204081632653061	0.260896951373142	0.981620396559986	0.999999999223096
GO:0038062	protein tyrosine kinase collagen receptor activity	1/1458	49/18639	0.0204081632653061	0.260896951373142	0.981620396559986	0.999999999223096
GO:0060175	brain-derived neurotrophic factor receptor activity	1/1458	49/18639	0.0204081632653061	0.260896951373142	0.981620396559986	0.999999999223096
GO:0008168	methyltransferase activity	9/1458	204/18639	0.0441176470588235	0.563997821350763	0.981688377973992	0.999999999223096
GO:0046906	tetrapyrrole binding	6/1458	152/18639	0.0394736842105263	0.50462962962963	0.982116737596055	0.999999999223096
GO:0101005	deubiquitinase activity	4/1458	115/18639	0.0347826086956522	0.444659151905529	0.982391138248275	0.999999999223096
GO:0005006	epidermal growth factor receptor activity	1/1458	50/18639	0.02	0.255679012345679	0.983061895312839	0.999999999223096
GO:0005007	fibroblast growth factor receptor activity	1/1458	50/18639	0.02	0.255679012345679	0.983061895312839	0.999999999223096
GO:0005017	platelet-derived growth factor receptor activity	1/1458	50/18639	0.02	0.255679012345679	0.983061895312839	0.999999999223096
GO:0005019	platelet-derived growth factor beta-receptor activity	1/1458	50/18639	0.02	0.255679012345679	0.983061895312839	0.999999999223096
GO:0015294	solute:monoatomic cation symporter activity	4/1458	116/18639	0.0344827586206897	0.440825883354619	0.98339215719929	0.999999999223096
GO:0005010	insulin-like growth factor receptor activity	1/1458	51/18639	0.0196078431372549	0.250665698378117	0.984390409844761	0.999999999223096
GO:0005021	vascular endothelial growth factor receptor activity	1/1458	51/18639	0.0196078431372549	0.250665698378117	0.984390409844761	0.999999999223096
GO:0005030	neurotrophin receptor activity	1/1458	51/18639	0.0196078431372549	0.250665698378117	0.984390409844761	0.999999999223096
GO:0005272	sodium channel activity	1/1458	51/18639	0.0196078431372549	0.250665698378117	0.984390409844761	0.999999999223096
GO:0016597	amino acid binding	1/1458	51/18639	0.0196078431372549	0.250665698378117	0.984390409844761	0.999999999223096
GO:0008170	N-methyltransferase activity	3/1458	98/18639	0.0306122448979592	0.391345427059713	0.985313545781665	0.999999999223096
GO:0022832	voltage-gated channel activity	7/1458	175/18639	0.04	0.511358024691358	0.986162511278061	0.999999999223096
GO:0005003	ephrin receptor activity	1/1458	53/18639	0.0188679245283019	0.241206615420452	0.986743193721811	0.999999999223096
GO:0005005	transmembrane-ephrin receptor activity	1/1458	53/18639	0.0188679245283019	0.241206615420452	0.986743193721811	0.999999999223096
GO:0038064	collagen receptor activity	1/1458	53/18639	0.0188679245283019	0.241206615420452	0.986743193721811	0.999999999223096
GO:0015370	solute:sodium symporter activity	2/1458	79/18639	0.0253164556962025	0.32364431942491	0.987760352494891	0.999999999223096
GO:0020037	heme binding	5/1458	142/18639	0.0352112676056338	0.450139106242393	0.988727671784086	0.999999999223096
GO:0008374	O-acyltransferase activity	1/1458	55/18639	0.0181818181818182	0.232435465768799	0.98874155621297	0.999999999223096
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	12/1458	268/18639	0.0447761194029851	0.572415699281371	0.989801894172201	0.999999999223096
GO:0015291	secondary active transmembrane transporter activity	13/1458	287/18639	0.0452961672473868	0.579063965242827	0.990728655960358	0.999999999223096
GO:0005254	chloride channel activity	2/1458	83/18639	0.0240963855421687	0.308047002826119	0.990785787981038	0.999999999223096
GO:0004714	transmembrane receptor protein tyrosine kinase activity	1/1458	60/18639	0.0166666666666667	0.213065843621399	0.992517578319131	0.999999999223096
GO:0019842	vitamin binding	5/1458	150/18639	0.0333333333333333	0.426131687242798	0.992845287645015	0.999999999223096
GO:0001217	DNA-binding transcription repressor activity	12/1458	278/18639	0.0431654676258993	0.551825206501465	0.993423673101139	0.999999999223096
GO:1901682	sulfur compound transmembrane transporter activity	1/1458	63/18639	0.0158730158730159	0.202919851067999	0.994144599777184	0.999999999223096
GO:0005244	voltage-gated monoatomic ion channel activity	6/1458	173/18639	0.0346820809248555	0.443374009847998	0.994192187928774	0.999999999223096
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	9/1458	229/18639	0.0393013100436681	0.502426006792819	0.994396801822015	0.999999999223096
GO:0016758	hexosyltransferase activity	7/1458	197/18639	0.0355329949238579	0.4542520523908	0.995588145237532	0.999999999223096
GO:0008173	RNA methyltransferase activity	1/1458	67/18639	0.0149253731343284	0.19080523309379	0.995777711405411	0.999999999223096
GO:0016500	protein-hormone receptor activity	1/1458	67/18639	0.0149253731343284	0.19080523309379	0.995777711405411	0.999999999223096
GO:0140767	enzyme-substrate adaptor activity	4/1458	139/18639	0.0287769784172662	0.367883471000977	0.995868051416496	0.999999999223096
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	6/1458	181/18639	0.0331491712707182	0.42377736852875	0.996281773848891	0.999999999223096
GO:0015108	chloride transmembrane transporter activity	3/1458	121/18639	0.0247933884297521	0.31695745332109	0.996736674857487	0.999999999223096
GO:0005249	voltage-gated potassium channel activity	2/1458	98/18639	0.0204081632653061	0.260896951373142	0.996871454540665	0.999999999223096
GO:0008528	G protein-coupled peptide receptor activity	3/1458	122/18639	0.0245901639344262	0.314359441408622	0.99694801985769	0.999999999223096
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	3/1458	122/18639	0.0245901639344262	0.314359441408622	0.99694801985769	0.999999999223096
GO:0015103	inorganic anion transmembrane transporter activity	5/1458	165/18639	0.0303030303030303	0.387392442947999	0.997025597463608	0.999999999223096
GO:0022836	gated channel activity	13/1458	318/18639	0.0408805031446541	0.522614333410979	0.99764983828647	0.999999999223096
GO:0140098	catalytic activity, acting on RNA	17/1458	387/18639	0.0439276485788114	0.561568890164928	0.997688182080877	0.999999999223096
GO:0061630	ubiquitin protein ligase activity	15/1458	353/18639	0.0424929178470255	0.543227363340678	0.997689710981627	0.999999999223096
GO:0061659	ubiquitin-like protein ligase activity	16/1458	372/18639	0.043010752688172	0.549847338377804	0.997874347484322	0.999999999223096
GO:0001653	peptide receptor activity	3/1458	128/18639	0.0234375	0.299623842592593	0.99796253322019	0.999999999223096
GO:0019199	transmembrane receptor protein kinase activity	1/1458	78/18639	0.0128205128205128	0.163896802785692	0.998282646578657	0.999999999223096
GO:0005179	hormone activity	3/1458	132/18639	0.0227272727272727	0.290544332210999	0.998446994992874	0.999999999223096
GO:0004222	metalloendopeptidase activity	2/1458	110/18639	0.0181818181818182	0.232435465768799	0.998700622754544	0.999999999223096
GO:0008237	metallopeptidase activity	5/1458	184/18639	0.0271739130434783	0.347389962426194	0.999060816587572	0.999999999223096
GO:0022843	voltage-gated monoatomic cation channel activity	3/1458	143/18639	0.020979020979021	0.268194768194768	0.999269833866416	0.999999999223096
GO:0005267	potassium channel activity	2/1458	124/18639	0.0161290322580645	0.206192751891677	0.999539889462879	0.999999999223096
GO:0030594	neurotransmitter receptor activity	1/1458	97/18639	0.0103092783505155	0.131793305332824	0.999637368161714	0.999999999223096
GO:0030527	structural constituent of chromatin	1/1458	98/18639	0.0102040816326531	0.130448475686571	0.999665882735127	0.999999999223096
GO:0099094	ligand-gated monoatomic cation channel activity	2/1458	136/18639	0.0147058823529412	0.187999273783588	0.999812777013845	0.999999999223096
GO:0004497	monooxygenase activity	1/1458	106/18639	0.00943396226415094	0.120603307710226	0.999826503458648	0.999999999223096
GO:0022834	ligand-gated channel activity	4/1458	188/18639	0.0212765957446809	0.271998949303914	0.999828062866903	0.999999999223096
GO:0015081	sodium ion transmembrane transporter activity	3/1458	164/18639	0.0182926829268293	0.233852755194219	0.99983194637018	0.999999999223096
GO:0015276	ligand-gated monoatomic ion channel activity	3/1458	186/18639	0.0161290322580645	0.206192751891677	0.999965092286384	0.999999999223096
GO:0015079	potassium ion transmembrane transporter activity	2/1458	160/18639	0.0125	0.159799382716049	0.999969641191717	0.999999999223096
GO:0045182	translation regulator activity	10/1458	356/18639	0.0280898876404494	0.35909973644056	0.999983611218441	0.999999999223096
GO:0140101	catalytic activity, acting on a tRNA	1/1458	139/18639	0.00719424460431655	0.0919708677502443	0.999988414158293	0.999999999223096
GO:0046873	metal ion transmembrane transporter activity	11/1458	450/18639	0.0244444444444444	0.312496570644719	0.99999979039471	0.999999999223096
GO:0030371	translation repressor activity	3/1458	329/18639	0.00911854103343465	0.116570978273106	0.999999999223096	0.999999999223096