ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	77/1602	495/18639	0.155555555555556	1.80986267166042	2.24041445638967e-07	0.000270866107777511
GO:0003713	transcription coactivator activity	44/1602	256/18639	0.171875	1.99973665730337	6.93645094568325e-06	0.00313895258890375
GO:0042054	histone methyltransferase activity	18/1602	67/18639	0.26865671641791	3.12577561630052	9.37463740158231e-06	0.00313895258890375
GO:0003714	transcription corepressor activity	37/1602	204/18639	0.181372549019608	2.110239039436	1.05899808069942e-05	0.00313895258890375
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	32/1602	167/18639	0.191616766467066	2.22942878288367	1.29816070674266e-05	0.00313895258890375
GO:0140996	histone H3 kinase activity	54/1602	357/18639	0.151260504201681	1.75989047304315	3.11739992830235e-05	0.00628156085552924
GO:0035173	histone kinase activity	54/1602	360/18639	0.15	1.74522471910112	3.93671902523577e-05	0.00679927614501435
GO:0042578	phosphoric ester hydrolase activity	54/1602	363/18639	0.148760330578512	1.73080137431516	4.94975904903607e-05	0.00746114500047888
GO:0016279	protein-lysine N-methyltransferase activity	17/1602	69/18639	0.246376811594203	2.86655267871682	5.55420223360711e-05	0.00746114500047888
GO:0016278	lysine N-methyltransferase activity	17/1602	70/18639	0.242857142857143	2.82560192616372	6.75497229903876e-05	0.00816676150953787
GO:0106310	protein serine kinase activity	53/1602	361/18639	0.146814404432133	1.70816085156712	8.22972645243204e-05	0.00858771361015047
GO:0140297	DNA-binding transcription factor binding	67/1602	488/18639	0.137295081967213	1.59740513906797	8.52378522099302e-05	0.00858771361015047
GO:0141003	histone H2AX kinase activity	52/1602	354/18639	0.146892655367232	1.70907128800863	9.43077568947467e-05	0.00877062139121144
GO:0048407	platelet-derived growth factor binding	6/1602	11/18639	0.545454545454545	6.34627170582227	0.000126281350409711	0.0109052966175243
GO:0008276	protein methyltransferase activity	20/1602	95/18639	0.210526315789474	2.44943820224719	0.000138951009993431	0.0110568766591492
GO:0004674	protein serine/threonine kinase activity	60/1602	433/18639	0.138568129330254	1.61221683057841	0.000151883068407119	0.0110568766591492
GO:0016791	phosphatase activity	42/1602	273/18639	0.153846153846154	1.78997407087295	0.000155473038217979	0.0110568766591492
GO:0016741	transferase activity, transferring one-carbon groups	35/1602	215/18639	0.162790697674419	1.89404233080742	0.000176943451494495	0.0118847018253803
GO:0008170	N-methyltransferase activity	20/1602	98/18639	0.204081632653061	2.37445540013758	0.000216636948898244	0.0137849511167356
GO:0008168	methyltransferase activity	33/1602	204/18639	0.161764705882353	1.8821050892267	0.000300716686717405	0.0181783237120671
GO:0051011	microtubule minus-end binding	6/1602	13/18639	0.461538461538462	5.36992221261884	0.00040328342773914	0.0232176030541248
GO:0140938	histone H3 methyltransferase activity	12/1602	47/18639	0.25531914893617	2.9705952665551	0.000474995855498565	0.0261031813317166
GO:0035402	histone H3T11 kinase activity	37/1602	247/18639	0.149797570850202	1.7428694900605	0.000625621720152552	0.0269846075319125
GO:0035403	histone H3T6 kinase activity	37/1602	247/18639	0.149797570850202	1.7428694900605	0.000625621720152552	0.0269846075319125
GO:0031267	small GTPase binding	41/1602	283/18639	0.144876325088339	1.68561162504467	0.000656423152648425	0.0269846075319125
GO:0004679	AMP-activated protein kinase activity	37/1602	248/18639	0.149193548387097	1.73584179050381	0.000675860192756995	0.0269846075319125
GO:0001222	transcription corepressor binding	12/1602	49/18639	0.244897959183673	2.8493464801651	0.000714223895989642	0.0269846075319125
GO:0001221	transcription coregulator binding	21/1602	115/18639	0.182608695652174	2.12462139716659	0.000737770861424236	0.0269846075319125
GO:0017056	structural constituent of nuclear pore	8/1602	25/18639	0.32	3.72314606741573	0.000835917285257362	0.0269846075319125
GO:0043394	proteoglycan binding	10/1602	37/18639	0.27027027027027	3.14454904342545	0.00085950741618999	0.0269846075319125
GO:0004676	3-phosphoinositide-dependent protein kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0004711	ribosomal protein S6 kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0035175	histone H3S10 kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0035979	histone H2AXS139 kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0044022	histone H3S28 kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0044023	histone H4S1 kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0044024	histone H2AS1 kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0044025	histone H2BS14 kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0072354	histone H3T3 kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0072371	histone H2AS121 kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0072518	Rho-dependent protein serine/threonine kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0140823	histone H2BS36 kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0140855	histone H3S57 kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0140995	histone H2A kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0140997	histone H4 kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0140998	histone H2B kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:1990244	histone H2AT120 kinase activity	36/1602	245/18639	0.146938775510204	1.70960788809906	0.00104902940777493	0.0269846075319125
GO:0004677	DNA-dependent protein kinase activity	36/1602	246/18639	0.146341463414634	1.70265826253768	0.00112965490379102	0.0278725056874151
GO:0140857	histone H3T45 kinase activity	36/1602	246/18639	0.146341463414634	1.70265826253768	0.00112965490379102	0.0278725056874151
GO:0042393	histone binding	36/1602	247/18639	0.145748987854251	1.69576490924806	0.00121565108678147	0.0293944432783759
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	47/1602	349/18639	0.134670487106017	1.5668684202054	0.00137998493633055	0.032713760549483
GO:0003725	double-stranded RNA binding	15/1602	75/18639	0.2	2.32696629213483	0.00158528305520707	0.0363864968655685
GO:0008013	beta-catenin binding	19/1602	106/18639	0.179245283018868	2.08548865804537	0.00161972348752479	0.0363864968655685
GO:0004177	aminopeptidase activity	10/1602	40/18639	0.25	2.90870786516854	0.00165008639449204	0.0363864968655685
GO:0051020	GTPase binding	43/1602	315/18639	0.136507936507936	1.58824683431425	0.00165529969198202	0.0363864968655685
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	35/1602	243/18639	0.1440329218107	1.67579877005595	0.00173304105355296	0.0374151184597417
GO:0043130	ubiquitin binding	18/1602	100/18639	0.18	2.09426966292135	0.00202043195378157	0.0428544251249458
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	5/1602	12/18639	0.416666666666667	4.84784644194757	0.00220663040529288	0.0437346911475261
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	5/1602	12/18639	0.416666666666667	4.84784644194757	0.00220663040529288	0.0437346911475261
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	5/1602	12/18639	0.416666666666667	4.84784644194757	0.00220663040529288	0.0437346911475261
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	5/1602	12/18639	0.416666666666667	4.84784644194757	0.00220663040529288	0.0437346911475261
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	33/1602	229/18639	0.14410480349345	1.67663510131986	0.00228758238015423	0.0446078564130076
GO:0005201	extracellular matrix structural constituent	26/1602	168/18639	0.154761904761905	1.80062867843767	0.00237800905129878	0.0456351260796861
GO:0061775	cohesin loader activity	24/1602	153/18639	0.156862745098039	1.82507160167438	0.00286006323804659	0.0540283821062238
GO:0035673	oligopeptide transmembrane transporter activity	5/1602	13/18639	0.384615384615385	4.47493517718237	0.00333372226626396	0.060156271939002
GO:0046974	histone H3K9 methyltransferase activity	5/1602	13/18639	0.384615384615385	4.47493517718237	0.00333372226626396	0.060156271939002
GO:0140852	histone ubiquitin ligase activity	5/1602	13/18639	0.384615384615385	4.47493517718237	0.00333372226626396	0.060156271939002
GO:0140098	catalytic activity, acting on RNA	49/1602	387/18639	0.126614987080103	1.47314403507244	0.00395499615195099	0.0703175051133639
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	7/1602	25/18639	0.28	3.25775280898876	0.00411999679571376	0.0721895090727237
GO:1990841	promoter-specific chromatin binding	13/1602	68/18639	0.191176470588235	2.22430601454065	0.00476191871671714	0.079671983744214
GO:0046030	inositol trisphosphate phosphatase activity	5/1602	14/18639	0.357142857142857	4.15529695024077	0.00482215668235018	0.079671983744214
GO:0043021	ribonucleoprotein complex binding	26/1602	177/18639	0.146892655367232	1.70907128800863	0.00488057848684852	0.079671983744214
GO:0000510	H3-H4 histone complex chaperone activity	23/1602	151/18639	0.152317880794702	1.77219287149341	0.00500832983007466	0.079671983744214
GO:0140584	chromatin extrusion motor activity	23/1602	151/18639	0.152317880794702	1.77219287149341	0.00500832983007466	0.079671983744214
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	23/1602	151/18639	0.152317880794702	1.77219287149341	0.00500832983007466	0.079671983744214
GO:0140849	ATP-dependent H2AZ histone chaperone activity	23/1602	151/18639	0.152317880794702	1.77219287149341	0.00500832983007466	0.079671983744214
GO:0003689	DNA clamp loader activity	24/1602	160/18639	0.15	1.74522471910112	0.00512096602718389	0.0799813892406023
GO:0015026	coreceptor activity	12/1602	61/18639	0.19672131147541	2.28881930373918	0.00516925134223668	0.0799813892406023
GO:0070006	metalloaminopeptidase activity	7/1602	26/18639	0.269230769230769	3.13245462402766	0.00522624462366219	0.0799813892406023
GO:0015616	DNA translocase activity	23/1602	152/18639	0.151315789473684	1.76053370786517	0.00543421509439673	0.0811106919645142
GO:0140674	ATP-dependent histone chaperone activity	23/1602	152/18639	0.151315789473684	1.76053370786517	0.00543421509439673	0.0811106919645142
GO:0015179	L-amino acid transmembrane transporter activity	12/1602	62/18639	0.193548387096774	2.25190286335629	0.00592017501212428	0.0872864828007105
GO:0050660	flavin adenine dinucleotide binding	15/1602	86/18639	0.174418604651163	2.02933106872224	0.00622190462471948	0.090629911943203
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	7/1602	27/18639	0.259259259259259	3.01643778610071	0.0065411300906387	0.0941455509474071
GO:0032182	ubiquitin-like protein binding	19/1602	120/18639	0.158333333333333	1.84218164794007	0.00671600980063354	0.0943222513322169
GO:0004559	alpha-mannosidase activity	5/1602	15/18639	0.333333333333333	3.87827715355805	0.00672728880218708	0.0943222513322169
GO:0140713	histone chaperone activity	24/1602	164/18639	0.146341463414634	1.70265826253768	0.00697555298474972	0.0943222513322169
GO:0052866	phosphatidylinositol phosphate phosphatase activity	8/1602	34/18639	0.235294117647059	2.73760740251157	0.00700828473056718	0.0943222513322169
GO:1904047	S-adenosyl-L-methionine binding	6/1602	21/18639	0.285714285714286	3.32423756019262	0.00700929438227368	0.0943222513322169
GO:0140030	modification-dependent protein binding	25/1602	173/18639	0.144508670520231	1.68133402610898	0.00702150754334121	0.0943222513322169
GO:0000182	rDNA binding	4/1602	10/18639	0.4	4.65393258426966	0.00748142141705552	0.0972584784217218
GO:0004445	inositol-polyphosphate 5-phosphatase activity	4/1602	10/18639	0.4	4.65393258426966	0.00748142141705552	0.0972584784217218
GO:0015924	mannosyl-oligosaccharide mannosidase activity	4/1602	10/18639	0.4	4.65393258426966	0.00748142141705552	0.0972584784217218
GO:0000049	tRNA binding	14/1602	80/18639	0.175	2.03609550561798	0.00782038403323263	0.100583449959343
GO:0008237	metallopeptidase activity	26/1602	184/18639	0.141304347826087	1.644052271617	0.00809581033484193	0.102130268076407
GO:0004721	phosphoprotein phosphatase activity	25/1602	175/18639	0.142857142857143	1.66211878009631	0.0081095994502358	0.102130268076407
GO:0000175	3'-5'-RNA exonuclease activity	8/1602	35/18639	0.228571428571429	2.65939004815409	0.00841495414973599	0.103813056806437
GO:0043015	gamma-tubulin binding	8/1602	35/18639	0.228571428571429	2.65939004815409	0.00841495414973599	0.103813056806437
GO:0140658	ATP-dependent chromatin remodeler activity	23/1602	158/18639	0.145569620253165	1.69367799743991	0.00866406300761263	0.105806587638421
GO:0140035	ubiquitin-like protein reader activity	6/1602	22/18639	0.272727272727273	3.17313585291113	0.00894912677843461	0.108194942751274
GO:0015923	mannosidase activity	5/1602	16/18639	0.3125	3.63588483146067	0.00910242679161885	0.108958752386804
GO:0004712	protein serine/threonine/tyrosine kinase activity	9/1602	43/18639	0.209302325581395	2.43519728246668	0.00969723308908152	0.114940733379407
GO:0016755	aminoacyltransferase activity	58/1602	496/18639	0.116935483870968	1.36052464661109	0.0100026144075136	0.116513140614849
GO:0016409	palmitoyltransferase activity	8/1602	36/18639	0.222222222222222	2.58551810237203	0.010022635751815	0.116513140614849
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	4/1602	11/18639	0.363636363636364	4.23084780388151	0.010965220348684	0.123896742070644
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4/1602	11/18639	0.363636363636364	4.23084780388151	0.010965220348684	0.123896742070644
GO:0097493	structural molecule activity conferring elasticity	4/1602	11/18639	0.363636363636364	4.23084780388151	0.010965220348684	0.123896742070644
GO:0004842	ubiquitin-protein transferase activity	53/1602	449/18639	0.11804008908686	1.37337654212858	0.0112409167648683	0.12402593666533
GO:0019787	ubiquitin-like protein transferase activity	56/1602	479/18639	0.116910229645094	1.36023081794938	0.0112690646273886	0.12402593666533
GO:0030020	extracellular matrix structural constituent conferring tensile strength	9/1602	44/18639	0.204545454545455	2.37985188968335	0.0112844111109895	0.12402593666533
GO:0004527	exonuclease activity	14/1602	84/18639	0.166666666666667	1.93913857677903	0.0119501676127066	0.129510959787362
GO:0004659	prenyltransferase activity	5/1602	17/18639	0.294117647058824	3.42200925313946	0.011997706779309	0.129510959787362
GO:0061659	ubiquitin-like protein ligase activity	45/1602	372/18639	0.120967741935484	1.40743928959768	0.0123184218880855	0.130804382875115
GO:0016779	nucleotidyltransferase activity	20/1602	136/18639	0.147058823529412	1.71100462656973	0.0123339120328893	0.130804382875115
GO:0061630	ubiquitin protein ligase activity	43/1602	353/18639	0.121813031161473	1.41727408727759	0.0126670442186263	0.133169186611471
GO:0051539	4 iron, 4 sulfur cluster binding	9/1602	45/18639	0.2	2.32696629213483	0.0130581089868419	0.13609701521631
GO:0016922	nuclear receptor binding	20/1602	137/18639	0.145985401459854	1.69851554170426	0.0133119088789389	0.136213074445485
GO:0004386	helicase activity	22/1602	155/18639	0.141935483870968	1.65139543312794	0.0133676450111639	0.136213074445485
GO:0016757	glycosyltransferase activity	34/1602	267/18639	0.127340823970037	1.48158902495476	0.0134072422324341	0.136213074445485
GO:0003724	RNA helicase activity	13/1602	77/18639	0.168831168831169	1.96432219465927	0.0136142880918279	0.137163952525166
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	8/1602	38/18639	0.210526315789474	2.44943820224719	0.0139050368057527	0.138935450397975
GO:0140097	catalytic activity, acting on DNA	41/1602	336/18639	0.12202380952381	1.41972645799893	0.0142566590382991	0.140840226433787
GO:0017147	Wnt-protein binding	7/1602	31/18639	0.225806451612903	2.627220007249	0.01432865827242	0.140840226433787
GO:0016273	arginine N-methyltransferase activity	4/1602	12/18639	0.333333333333333	3.87827715355805	0.0153445153203795	0.14723427795507
GO:0016274	protein-arginine N-methyltransferase activity	4/1602	12/18639	0.333333333333333	3.87827715355805	0.0153445153203795	0.14723427795507
GO:0045295	gamma-catenin binding	4/1602	12/18639	0.333333333333333	3.87827715355805	0.0153445153203795	0.14723427795507
GO:0097110	scaffold protein binding	12/1602	70/18639	0.171428571428571	1.99454253611557	0.0154797254814829	0.147362111079628
GO:0004713	protein tyrosine kinase activity	20/1602	140/18639	0.142857142857143	1.66211878009631	0.0166179877330876	0.156385840296615
GO:0008186	ATP-dependent activity, acting on RNA	13/1602	79/18639	0.164556962025316	1.91459251884511	0.0166863303542293	0.156385840296615
GO:0019706	protein-cysteine S-palmitoyltransferase activity	6/1602	25/18639	0.24	2.7923595505618	0.017022062628691	0.157096745939599
GO:0019707	protein-cysteine S-acyltransferase activity	6/1602	25/18639	0.24	2.7923595505618	0.017022062628691	0.157096745939599
GO:0004532	RNA exonuclease activity	8/1602	40/18639	0.2	2.32696629213483	0.0187809420690855	0.169238335679604
GO:0015036	disulfide oxidoreductase activity	8/1602	40/18639	0.2	2.32696629213483	0.0187809420690855	0.169238335679604
GO:0017124	SH3 domain binding	17/1602	115/18639	0.147826086956522	1.71993160723009	0.0190375629879455	0.169238335679604
GO:0035401	histone H3Y41 kinase activity	17/1602	115/18639	0.147826086956522	1.71993160723009	0.0190375629879455	0.169238335679604
GO:0140801	histone H2AXY142 kinase activity	17/1602	115/18639	0.147826086956522	1.71993160723009	0.0190375629879455	0.169238335679604
GO:0042800	histone H3K4 methyltransferase activity	5/1602	19/18639	0.263157894736842	3.06179775280899	0.0195278885216362	0.169850483616246
GO:0043395	heparan sulfate proteoglycan binding	5/1602	19/18639	0.263157894736842	3.06179775280899	0.0195278885216362	0.169850483616246
GO:0140036	ubiquitin-modified protein reader activity	5/1602	19/18639	0.263157894736842	3.06179775280899	0.0195278885216362	0.169850483616246
GO:0004535	poly(A)-specific ribonuclease activity	4/1602	13/18639	0.307692307692308	3.57994814174589	0.0206826455666531	0.174862367063521
GO:0043560	insulin receptor substrate binding	4/1602	13/18639	0.307692307692308	3.57994814174589	0.0206826455666531	0.174862367063521
GO:0046975	histone H3K36 methyltransferase activity	4/1602	13/18639	0.307692307692308	3.57994814174589	0.0206826455666531	0.174862367063521
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	4/1602	13/18639	0.307692307692308	3.57994814174589	0.0206826455666531	0.174862367063521
GO:0019902	phosphatase binding	25/1602	190/18639	0.131578947368421	1.53089887640449	0.0213914778325267	0.179599282635589
GO:0038024	cargo receptor activity	11/1602	65/18639	0.169230769230769	1.96897147796024	0.0218217517231611	0.181948260919322
GO:0016887	ATP hydrolysis activity	48/1602	417/18639	0.115107913669065	1.3392611753294	0.0230168518638853	0.190598451393406
GO:0015035	protein-disulfide reductase activity	7/1602	34/18639	0.205882352941176	2.39540647719762	0.023416488206201	0.192588668308143
GO:0016004	phospholipase activator activity	5/1602	20/18639	0.25	2.90870786516854	0.0242396009937054	0.195371184009266
GO:0052745	inositol phosphate phosphatase activity	5/1602	20/18639	0.25	2.90870786516854	0.0242396009937054	0.195371184009266
GO:0140939	histone H4 methyltransferase activity	5/1602	20/18639	0.25	2.90870786516854	0.0242396009937054	0.195371184009266
GO:0035198	miRNA binding	8/1602	42/18639	0.19047619047619	2.21615837346174	0.0247687321311149	0.197921413695977
GO:0008408	3'-5' exonuclease activity	10/1602	58/18639	0.172413793103448	2.00600542425417	0.0248834200841923	0.197921413695977
GO:0004222	metalloendopeptidase activity	16/1602	110/18639	0.145454545454545	1.6923391215526	0.0257518257064851	0.203489916857128
GO:0005161	platelet-derived growth factor receptor binding	4/1602	14/18639	0.285714285714286	3.32423756019262	0.0270268411203742	0.205505980594544
GO:0008174	mRNA methyltransferase activity	4/1602	14/18639	0.285714285714286	3.32423756019262	0.0270268411203742	0.205505980594544
GO:0008474	palmitoyl-(protein) hydrolase activity	4/1602	14/18639	0.285714285714286	3.32423756019262	0.0270268411203742	0.205505980594544
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	4/1602	14/18639	0.285714285714286	3.32423756019262	0.0270268411203742	0.205505980594544
GO:0098599	palmitoyl hydrolase activity	4/1602	14/18639	0.285714285714286	3.32423756019262	0.0270268411203742	0.205505980594544
GO:1990825	sequence-specific mRNA binding	4/1602	14/18639	0.285714285714286	3.32423756019262	0.0270268411203742	0.205505980594544
GO:0031593	polyubiquitin modification-dependent protein binding	10/1602	59/18639	0.169491525423729	1.97200533231765	0.0277340241088929	0.209565219672822
GO:0051010	microtubule plus-end binding	5/1602	21/18639	0.238095238095238	2.77019796682718	0.0296240718097778	0.222456539242369
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	10/1602	60/18639	0.166666666666667	1.93913857677903	0.0308095220735058	0.229930322141163
GO:0000993	RNA polymerase II complex binding	7/1602	36/18639	0.194444444444444	2.26232833957553	0.0313051355747833	0.232195760183516
GO:0002039	p53 binding	11/1602	69/18639	0.159420289855072	1.85482820387559	0.0325645639618239	0.235886721511036
GO:0140597	protein carrier chaperone	24/1602	188/18639	0.127659574468085	1.48529763327755	0.0326740280197865	0.235886721511036
GO:0016417	S-acyltransferase activity	6/1602	29/18639	0.206896551724138	2.407206509105	0.0340631489313948	0.235886721511036
GO:0008081	phosphoric diester hydrolase activity	13/1602	87/18639	0.149425287356322	1.73853803435361	0.0343992567519615	0.235886721511036
GO:0010181	FMN binding	4/1602	15/18639	0.266666666666667	3.10262172284644	0.034408496508806	0.235886721511036
GO:0016407	acetyltransferase activity	14/1602	96/18639	0.145833333333333	1.69674625468165	0.0347161662962908	0.235886721511036
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	5/1602	22/18639	0.227272727272727	2.64427987742594	0.035704937995467	0.235886721511036
GO:0032931	histone H3K56 acetyltransferase activity	5/1602	22/18639	0.227272727272727	2.64427987742594	0.035704937995467	0.235886721511036
GO:0043992	histone H3K9 acetyltransferase activity	5/1602	22/18639	0.227272727272727	2.64427987742594	0.035704937995467	0.235886721511036
GO:0043993	histone H3K18 acetyltransferase activity	5/1602	22/18639	0.227272727272727	2.64427987742594	0.035704937995467	0.235886721511036
GO:0043994	histone H3K23 acetyltransferase activity	5/1602	22/18639	0.227272727272727	2.64427987742594	0.035704937995467	0.235886721511036
GO:0043999	histone H2AK5 acetyltransferase activity	5/1602	22/18639	0.227272727272727	2.64427987742594	0.035704937995467	0.235886721511036
GO:0044012	histone H2AK9 acetyltransferase activity	5/1602	22/18639	0.227272727272727	2.64427987742594	0.035704937995467	0.235886721511036
GO:0044014	histone H2BK5 acetyltransferase activity	5/1602	22/18639	0.227272727272727	2.64427987742594	0.035704937995467	0.235886721511036
GO:0044015	histone H2BK12 acetyltransferase activity	5/1602	22/18639	0.227272727272727	2.64427987742594	0.035704937995467	0.235886721511036
GO:0044016	histone H3K4 acetyltransferase activity	5/1602	22/18639	0.227272727272727	2.64427987742594	0.035704937995467	0.235886721511036
GO:0044017	histone H3K27 acetyltransferase activity	5/1602	22/18639	0.227272727272727	2.64427987742594	0.035704937995467	0.235886721511036
GO:0044018	histone H3K36 acetyltransferase activity	5/1602	22/18639	0.227272727272727	2.64427987742594	0.035704937995467	0.235886721511036
GO:0046972	histone H4K16 acetyltransferase activity	5/1602	22/18639	0.227272727272727	2.64427987742594	0.035704937995467	0.235886721511036
GO:0140908	histone H3K122 acetyltransferase activity	5/1602	22/18639	0.227272727272727	2.64427987742594	0.035704937995467	0.235886721511036
GO:0140303	intramembrane lipid transporter activity	8/1602	45/18639	0.177777777777778	2.06841448189763	0.0360659880507558	0.236853767373016
GO:0001217	DNA-binding transcription repressor activity	33/1602	278/18639	0.118705035971223	1.38111308705844	0.0362431323110073	0.236853767373016
GO:0004197	cysteine-type endopeptidase activity	13/1602	88/18639	0.147727272727273	1.71878192032686	0.0373104469244897	0.241519731174564
GO:0140104	molecular carrier activity	30/1602	249/18639	0.120481927710843	1.40178692297279	0.0373566499004496	0.241519731174564
GO:0008094	ATP-dependent activity, acting on DNA	26/1602	210/18639	0.123809523809524	1.44050294275013	0.0376416558784642	0.242067882750336
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	9/1602	54/18639	0.166666666666667	1.93913857677903	0.0393236598388315	0.25154658595316
GO:0005096	GTPase activator activity	32/1602	271/18639	0.118081180811808	1.37385463742278	0.0411536396545152	0.261867107064784
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	5/1602	23/18639	0.217391304347826	2.52931118710308	0.042499562784547	0.262935118655699
GO:0044013	histone H2B acetyltransferase activity	5/1602	23/18639	0.217391304347826	2.52931118710308	0.042499562784547	0.262935118655699
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	5/1602	23/18639	0.217391304347826	2.52931118710308	0.042499562784547	0.262935118655699
GO:0004708	MAP kinase kinase activity	4/1602	16/18639	0.25	2.90870786516854	0.0428438530812016	0.262935118655699
GO:0005024	transforming growth factor beta receptor activity	4/1602	16/18639	0.25	2.90870786516854	0.0428438530812016	0.262935118655699
GO:0015562	efflux transmembrane transporter activity	4/1602	16/18639	0.25	2.90870786516854	0.0428438530812016	0.262935118655699
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	4/1602	16/18639	0.25	2.90870786516854	0.0428438530812016	0.262935118655699
GO:0015101	organic cation transmembrane transporter activity	12/1602	81/18639	0.148148148148148	1.72367873491469	0.0434416068012144	0.26525708395287
GO:0070325	lipoprotein particle receptor binding	6/1602	31/18639	0.193548387096774	2.25190286335629	0.0456517279035001	0.275964695176658
GO:0072349	modified amino acid transmembrane transporter activity	6/1602	31/18639	0.193548387096774	2.25190286335629	0.0456517279035001	0.275964695176658
GO:0035091	phosphatidylinositol binding	33/1602	284/18639	0.116197183098592	1.35193464155721	0.0466553121021367	0.279401615553298
GO:0004382	GDP phosphatase activity	3/1602	10/18639	0.3	3.49044943820225	0.0480690951489544	0.279401615553298
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	3/1602	10/18639	0.3	3.49044943820225	0.0480690951489544	0.279401615553298
GO:0032356	oxidized DNA binding	3/1602	10/18639	0.3	3.49044943820225	0.0480690951489544	0.279401615553298
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	3/1602	10/18639	0.3	3.49044943820225	0.0480690951489544	0.279401615553298
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	3/1602	10/18639	0.3	3.49044943820225	0.0480690951489544	0.279401615553298
GO:0051864	histone H3K36 demethylase activity	3/1602	10/18639	0.3	3.49044943820225	0.0480690951489544	0.279401615553298
GO:1990763	arrestin family protein binding	3/1602	10/18639	0.3	3.49044943820225	0.0480690951489544	0.279401615553298
GO:1901681	sulfur compound binding	32/1602	275/18639	0.116363636363636	1.35387129724208	0.0486800992970573	0.281599234689676
GO:0043998	histone H2A acetyltransferase activity	5/1602	24/18639	0.208333333333333	2.42392322097378	0.0500190354044867	0.286601961156514
GO:0060229	lipase activator activity	5/1602	24/18639	0.208333333333333	2.42392322097378	0.0500190354044867	0.286601961156514
GO:0032266	phosphatidylinositol-3-phosphate binding	8/1602	48/18639	0.166666666666667	1.93913857677903	0.0504003111190046	0.287424415768285
GO:0008017	microtubule binding	32/1602	276/18639	0.115942028985507	1.34896596645497	0.0507105965238381	0.28783620280432
GO:0008234	cysteine-type peptidase activity	23/1602	187/18639	0.122994652406417	1.43102205131286	0.0513325381168669	0.290004853192954
GO:0071949	FAD binding	7/1602	40/18639	0.175	2.03609550561798	0.0519897737954587	0.290243049538885
GO:0022884	macromolecule transmembrane transporter activity	6/1602	32/18639	0.1875	2.1815308988764	0.0522601518307267	0.290243049538885
GO:0046965	nuclear retinoid X receptor binding	4/1602	17/18639	0.235294117647059	2.73760740251157	0.0523349750202455	0.290243049538885
GO:0070403	NAD+ binding	4/1602	17/18639	0.235294117647059	2.73760740251157	0.0523349750202455	0.290243049538885
GO:0019207	kinase regulator activity	33/1602	287/18639	0.114982578397213	1.33780292056532	0.0526243341412747	0.290515159711421
GO:0008238	exopeptidase activity	14/1602	102/18639	0.137254901960784	1.59693765146508	0.0537497987964858	0.294043016945481
GO:0015171	amino acid transmembrane transporter activity	14/1602	102/18639	0.137254901960784	1.59693765146508	0.0537497987964858	0.294043016945481
GO:0008235	metalloexopeptidase activity	10/1602	66/18639	0.151515151515152	1.7628532516173	0.0543863024095558	0.295534042048348
GO:0051213	dioxygenase activity	13/1602	93/18639	0.139784946236559	1.62637429020176	0.0545112418335663	0.295534042048348
GO:0016763	pentosyltransferase activity	8/1602	49/18639	0.163265306122449	1.89956432011007	0.055891453254026	0.301664138321953
GO:0031072	heat shock protein binding	17/1602	131/18639	0.129770992366412	1.50986362466764	0.0567426832771444	0.304897351475856
GO:0061980	regulatory RNA binding	9/1602	58/18639	0.155172413793103	1.80540488182875	0.0581333092134847	0.308975214146968
GO:0042169	SH2 domain binding	7/1602	41/18639	0.170731707317073	1.9864346396273	0.0582405539176138	0.308975214146968
GO:0000030	mannosyltransferase activity	5/1602	25/18639	0.2	2.32696629213483	0.0582682785984356	0.308975214146968
GO:0008173	RNA methyltransferase activity	10/1602	67/18639	0.149253731343284	1.73654200905584	0.0592248137247165	0.312675981629617
GO:0000287	magnesium ion binding	27/1602	230/18639	0.117391304347826	1.36582804103566	0.0602537231832244	0.314094831062493
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	3/1602	11/18639	0.272727272727273	3.17313585291113	0.0619830481990557	0.314094831062493
GO:0000099	sulfur amino acid transmembrane transporter activity	3/1602	11/18639	0.272727272727273	3.17313585291113	0.0619830481990557	0.314094831062493
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	3/1602	11/18639	0.272727272727273	3.17313585291113	0.0619830481990557	0.314094831062493
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	3/1602	11/18639	0.272727272727273	3.17313585291113	0.0619830481990557	0.314094831062493
GO:0035252	UDP-xylosyltransferase activity	3/1602	11/18639	0.272727272727273	3.17313585291113	0.0619830481990557	0.314094831062493
GO:0042285	xylosyltransferase activity	3/1602	11/18639	0.272727272727273	3.17313585291113	0.0619830481990557	0.314094831062493
GO:0048185	activin binding	3/1602	11/18639	0.272727272727273	3.17313585291113	0.0619830481990557	0.314094831062493
GO:0050786	RAGE receptor binding	3/1602	11/18639	0.272727272727273	3.17313585291113	0.0619830481990557	0.314094831062493
GO:0044389	ubiquitin-like protein ligase binding	36/1602	322/18639	0.111801242236025	1.30078861051015	0.0622890893594666	0.314094831062493
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	4/1602	18/18639	0.222222222222222	2.58551810237203	0.0628709256551889	0.314094831062493
GO:0017128	phospholipid scramblase activity	4/1602	18/18639	0.222222222222222	2.58551810237203	0.0628709256551889	0.314094831062493
GO:0034185	apolipoprotein binding	4/1602	18/18639	0.222222222222222	2.58551810237203	0.0628709256551889	0.314094831062493
GO:0036002	pre-mRNA binding	9/1602	59/18639	0.152542372881356	1.77480479908589	0.0636051805323112	0.316455404376807
GO:0030695	GTPase regulator activity	52/1602	489/18639	0.106339468302658	1.23724179131913	0.0639833372785145	0.317032191679197
GO:0004402	histone acetyltransferase activity	7/1602	42/18639	0.166666666666667	1.93913857677903	0.0649349182749136	0.317839336819314
GO:0004520	DNA endonuclease activity	7/1602	42/18639	0.166666666666667	1.93913857677903	0.0649349182749136	0.317839336819314
GO:0043175	RNA polymerase core enzyme binding	7/1602	42/18639	0.166666666666667	1.93913857677903	0.0649349182749136	0.317839336819314
GO:0060589	nucleoside-triphosphatase regulator activity	52/1602	490/18639	0.106122448979592	1.23471680807154	0.0658381602851627	0.320961031390168
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	6/1602	34/18639	0.176470588235294	2.05320555188367	0.067135714572199	0.32262187923671
GO:0005112	Notch binding	5/1602	26/18639	0.192307692307692	2.23746758859118	0.0672462477813489	0.32262187923671
GO:0043548	phosphatidylinositol 3-kinase binding	5/1602	26/18639	0.192307692307692	2.23746758859118	0.0672462477813489	0.32262187923671
GO:0050750	low-density lipoprotein particle receptor binding	5/1602	26/18639	0.192307692307692	2.23746758859118	0.0672462477813489	0.32262187923671
GO:0019199	transmembrane receptor protein kinase activity	11/1602	78/18639	0.141025641025641	1.64080956496687	0.0693010425565373	0.327717630678005
GO:0001098	basal transcription machinery binding	9/1602	60/18639	0.15	1.74522471910112	0.0693926496721004	0.327717630678005
GO:0001099	basal RNA polymerase II transcription machinery binding	9/1602	60/18639	0.15	1.74522471910112	0.0693926496721004	0.327717630678005
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	9/1602	60/18639	0.15	1.74522471910112	0.0693926496721004	0.327717630678005
GO:0042577	lipid phosphatase activity	4/1602	19/18639	0.210526315789474	2.44943820224719	0.0744290688908029	0.346095170342233
GO:0046527	glucosyltransferase activity	4/1602	19/18639	0.210526315789474	2.44943820224719	0.0744290688908029	0.346095170342233
GO:0070003	threonine-type peptidase activity	4/1602	19/18639	0.210526315789474	2.44943820224719	0.0744290688908029	0.346095170342233
GO:1990380	K48-linked deubiquitinase activity	4/1602	19/18639	0.210526315789474	2.44943820224719	0.0744290688908029	0.346095170342233
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	9/1602	61/18639	0.147540983606557	1.71661447780438	0.0754979267720803	0.348449197110651
GO:0005044	scavenger receptor activity	5/1602	27/18639	0.185185185185185	2.15459841864336	0.0769462063001451	0.348449197110651
GO:0005385	zinc ion transmembrane transporter activity	5/1602	27/18639	0.185185185185185	2.15459841864336	0.0769462063001451	0.348449197110651
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	5/1602	27/18639	0.185185185185185	2.15459841864336	0.0769462063001451	0.348449197110651
GO:0000340	RNA 7-methylguanosine cap binding	3/1602	12/18639	0.25	2.90870786516854	0.0775292258252813	0.348449197110651
GO:0003995	acyl-CoA dehydrogenase activity	3/1602	12/18639	0.25	2.90870786516854	0.0775292258252813	0.348449197110651
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	3/1602	12/18639	0.25	2.90870786516854	0.0775292258252813	0.348449197110651
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	3/1602	12/18639	0.25	2.90870786516854	0.0775292258252813	0.348449197110651
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	3/1602	12/18639	0.25	2.90870786516854	0.0775292258252813	0.348449197110651
GO:0001223	transcription coactivator binding	7/1602	44/18639	0.159090909090909	1.85099591419816	0.0796615513066567	0.355390463209402
GO:0043014	alpha-tubulin binding	7/1602	44/18639	0.159090909090909	1.85099591419816	0.0796615513066567	0.355390463209402
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	30/1602	268/18639	0.111940298507463	1.30240650679188	0.0816150119179864	0.361611211332799
GO:0016758	hexosyltransferase activity	23/1602	197/18639	0.116751269035533	1.35838133804825	0.0816541444945031	0.361611211332799
GO:0019209	kinase activator activity	18/1602	148/18639	0.121621621621622	1.41504706954145	0.084364820134797	0.372252071324707
GO:0042277	peptide binding	28/1602	249/18639	0.112449799196787	1.30833446144127	0.0861836007196125	0.378542935887623
GO:0000339	RNA cap binding	4/1602	20/18639	0.2	2.32696629213483	0.0869764358650773	0.378542935887623
GO:0015095	magnesium ion transmembrane transporter activity	4/1602	20/18639	0.2	2.32696629213483	0.0869764358650773	0.378542935887623
GO:0019789	SUMO transferase activity	5/1602	28/18639	0.178571428571429	2.07764847512039	0.087356062127913	0.378542935887623
GO:0036408	histone H3K14 acetyltransferase activity	5/1602	28/18639	0.178571428571429	2.07764847512039	0.087356062127913	0.378542935887623
GO:0140767	enzyme-substrate adaptor activity	17/1602	139/18639	0.122302158273381	1.42296499878749	0.0879443328151969	0.379731065619904
GO:0004518	nuclease activity	24/1602	209/18639	0.114832535885167	1.33605720122574	0.0885362424554198	0.380926395475454
GO:0015631	tubulin binding	41/1602	385/18639	0.106493506493506	1.23903399970816	0.0895401903338471	0.383879752175962
GO:0061459	L-arginine transmembrane transporter activity	3/1602	13/18639	0.230769230769231	2.68496110630942	0.0945831999028697	0.404067451175157
GO:0008374	O-acyltransferase activity	8/1602	55/18639	0.145454545454545	1.6923391215526	0.0965991330347466	0.411226590982425
GO:0004629	phospholipase C activity	5/1602	29/18639	0.172413793103448	2.00600542425417	0.0984587523771875	0.416211998685384
GO:0010484	histone H3 acetyltransferase activity	5/1602	29/18639	0.172413793103448	2.00600542425417	0.0984587523771875	0.416211998685384
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	4/1602	21/18639	0.19047619047619	2.21615837346174	0.100471109760442	0.418848939610285
GO:0010314	phosphatidylinositol-5-phosphate binding	4/1602	21/18639	0.19047619047619	2.21615837346174	0.100471109760442	0.418848939610285
GO:0015174	basic amino acid transmembrane transporter activity	4/1602	21/18639	0.19047619047619	2.21615837346174	0.100471109760442	0.418848939610285
GO:0019200	carbohydrate kinase activity	4/1602	21/18639	0.19047619047619	2.21615837346174	0.100471109760442	0.418848939610285
GO:0035064	methylated histone binding	10/1602	74/18639	0.135135135135135	1.57227452171272	0.100814757176669	0.418848939610285
GO:0042887	amide transmembrane transporter activity	6/1602	38/18639	0.157894736842105	1.83707865168539	0.10348699149584	0.428478673693391
GO:0061733	protein-lysine-acetyltransferase activity	7/1602	47/18639	0.148936170212766	1.73284723882381	0.105070096394861	0.432073967827845
GO:0140359	ABC-type transporter activity	7/1602	47/18639	0.148936170212766	1.73284723882381	0.105070096394861	0.432073967827845
GO:0019887	protein kinase regulator activity	28/1602	255/18639	0.109803921568627	1.27755012117206	0.107150101411177	0.438445632543642
GO:0016410	N-acyltransferase activity	12/1602	94/18639	0.127659574468085	1.48529763327755	0.107344836420941	0.438445632543642
GO:0008187	poly-pyrimidine tract binding	5/1602	30/18639	0.166666666666667	1.93913857677903	0.110232663193128	0.43983924026565
GO:0032452	histone demethylase activity	5/1602	30/18639	0.166666666666667	1.93913857677903	0.110232663193128	0.43983924026565
GO:0043995	histone H4K5 acetyltransferase activity	5/1602	30/18639	0.166666666666667	1.93913857677903	0.110232663193128	0.43983924026565
GO:0043996	histone H4K8 acetyltransferase activity	5/1602	30/18639	0.166666666666667	1.93913857677903	0.110232663193128	0.43983924026565
GO:0043997	histone H4K12 acetyltransferase activity	5/1602	30/18639	0.166666666666667	1.93913857677903	0.110232663193128	0.43983924026565
GO:0051721	protein phosphatase 2A binding	5/1602	30/18639	0.166666666666667	1.93913857677903	0.110232663193128	0.43983924026565
GO:0070566	adenylyltransferase activity	5/1602	30/18639	0.166666666666667	1.93913857677903	0.110232663193128	0.43983924026565
GO:0005313	L-glutamate transmembrane transporter activity	3/1602	14/18639	0.214285714285714	2.49317817014446	0.113007661389005	0.445036686056374
GO:0008559	ABC-type xenobiotic transporter activity	3/1602	14/18639	0.214285714285714	2.49317817014446	0.113007661389005	0.445036686056374
GO:0032454	histone H3K9 demethylase activity	3/1602	14/18639	0.214285714285714	2.49317817014446	0.113007661389005	0.445036686056374
GO:0098847	sequence-specific single stranded DNA binding	3/1602	14/18639	0.214285714285714	2.49317817014446	0.113007661389005	0.445036686056374
GO:0004407	histone deacetylase activity	4/1602	22/18639	0.181818181818182	2.11542390194076	0.114863592374881	0.447816489853578
GO:0033558	protein lysine deacetylase activity	4/1602	22/18639	0.181818181818182	2.11542390194076	0.114863592374881	0.447816489853578
GO:0051536	iron-sulfur cluster binding	10/1602	76/18639	0.131578947368421	1.53089887640449	0.115195143378381	0.447816489853578
GO:0140034	methylation-dependent protein binding	10/1602	76/18639	0.131578947368421	1.53089887640449	0.115195143378381	0.447816489853578
GO:0004175	endopeptidase activity	42/1602	405/18639	0.103703703703704	1.20657511444028	0.116901062636327	0.452991617715767
GO:0008514	organic anion transmembrane transporter activity	29/1602	269/18639	0.107806691449814	1.25431268535149	0.121038228900054	0.461860494816212
GO:0140457	protein demethylase activity	5/1602	31/18639	0.161290322580645	1.87658571946357	0.122652073825749	0.461860494816212
GO:0051540	metal cluster binding	10/1602	77/18639	0.12987012987013	1.51101707281483	0.122794011419226	0.461860494816212
GO:0005004	GPI-linked ephrin receptor activity	7/1602	49/18639	0.142857142857143	1.66211878009631	0.124156046993605	0.461860494816212
GO:0005008	hepatocyte growth factor receptor activity	7/1602	49/18639	0.142857142857143	1.66211878009631	0.124156046993605	0.461860494816212
GO:0005009	insulin receptor activity	7/1602	49/18639	0.142857142857143	1.66211878009631	0.124156046993605	0.461860494816212
GO:0005011	macrophage colony-stimulating factor receptor activity	7/1602	49/18639	0.142857142857143	1.66211878009631	0.124156046993605	0.461860494816212
GO:0005018	platelet-derived growth factor alpha-receptor activity	7/1602	49/18639	0.142857142857143	1.66211878009631	0.124156046993605	0.461860494816212
GO:0005020	stem cell factor receptor activity	7/1602	49/18639	0.142857142857143	1.66211878009631	0.124156046993605	0.461860494816212
GO:0008288	boss receptor activity	7/1602	49/18639	0.142857142857143	1.66211878009631	0.124156046993605	0.461860494816212
GO:0036332	placental growth factor receptor activity	7/1602	49/18639	0.142857142857143	1.66211878009631	0.124156046993605	0.461860494816212
GO:0038062	protein tyrosine kinase collagen receptor activity	7/1602	49/18639	0.142857142857143	1.66211878009631	0.124156046993605	0.461860494816212
GO:0060175	brain-derived neurotrophic factor receptor activity	7/1602	49/18639	0.142857142857143	1.66211878009631	0.124156046993605	0.461860494816212
GO:0031625	ubiquitin protein ligase binding	32/1602	302/18639	0.105960264900662	1.23282982364759	0.127010781453945	0.471030781527053
GO:0019783	ubiquitin-like protein peptidase activity	15/1602	127/18639	0.118110236220472	1.37419269220561	0.129163292996449	0.47608460865823
GO:0005158	insulin receptor binding	4/1602	23/18639	0.173913043478261	2.02344894968246	0.130098124920214	0.47608460865823
GO:0008171	O-methyltransferase activity	4/1602	23/18639	0.173913043478261	2.02344894968246	0.130098124920214	0.47608460865823
GO:0005319	lipid transporter activity	20/1602	178/18639	0.112359550561798	1.30728443378361	0.130932271753223	0.47608460865823
GO:0070063	RNA polymerase binding	8/1602	59/18639	0.135593220338983	1.57760426585412	0.131065140769001	0.47608460865823
GO:0070888	E-box binding	8/1602	59/18639	0.135593220338983	1.57760426585412	0.131065140769001	0.47608460865823
GO:0004129	cytochrome-c oxidase activity	3/1602	15/18639	0.2	2.32696629213483	0.132657452609054	0.47608460865823
GO:0042809	nuclear vitamin D receptor binding	3/1602	15/18639	0.2	2.32696629213483	0.132657452609054	0.47608460865823
GO:0141050	histone H3K deacetylase activity	3/1602	15/18639	0.2	2.32696629213483	0.132657452609054	0.47608460865823
GO:0141051	histone H4K deacetylase activity	3/1602	15/18639	0.2	2.32696629213483	0.132657452609054	0.47608460865823
GO:0005006	epidermal growth factor receptor activity	7/1602	50/18639	0.14	1.62887640449438	0.134315419242037	0.47608460865823
GO:0005007	fibroblast growth factor receptor activity	7/1602	50/18639	0.14	1.62887640449438	0.134315419242037	0.47608460865823
GO:0005017	platelet-derived growth factor receptor activity	7/1602	50/18639	0.14	1.62887640449438	0.134315419242037	0.47608460865823
GO:0005019	platelet-derived growth factor beta-receptor activity	7/1602	50/18639	0.14	1.62887640449438	0.134315419242037	0.47608460865823
GO:0048020	CCR chemokine receptor binding	7/1602	50/18639	0.14	1.62887640449438	0.134315419242037	0.47608460865823
GO:0043425	bHLH transcription factor binding	5/1602	32/18639	0.15625	1.81794241573034	0.135687614935938	0.47608460865823
GO:0070717	poly-purine tract binding	5/1602	32/18639	0.15625	1.81794241573034	0.135687614935938	0.47608460865823
GO:0008080	N-acetyltransferase activity	9/1602	69/18639	0.130434782608696	1.51758671226185	0.13571921720889	0.47608460865823
GO:0015175	neutral L-amino acid transmembrane transporter activity	6/1602	41/18639	0.146341463414634	1.70265826253768	0.136249193214018	0.47608460865823
GO:0140318	protein transporter activity	6/1602	41/18639	0.146341463414634	1.70265826253768	0.136249193214018	0.47608460865823
GO:0046332	SMAD binding	10/1602	79/18639	0.126582278481013	1.4727634760347	0.138790580205411	0.483567180024039
GO:0003727	single-stranded RNA binding	11/1602	89/18639	0.123595505617978	1.43801287716197	0.140716827804968	0.487083534009316
GO:0030295	protein kinase activator activity	16/1602	139/18639	0.115107913669065	1.3392611753294	0.141008467248355	0.487083534009316
GO:0140101	catalytic activity, acting on a tRNA	16/1602	139/18639	0.115107913669065	1.3392611753294	0.141008467248355	0.487083534009316
GO:0016782	transferase activity, transferring sulphur-containing groups	9/1602	70/18639	0.128571428571429	1.49590690208668	0.144621504665018	0.493440661657659
GO:0005010	insulin-like growth factor receptor activity	7/1602	51/18639	0.137254901960784	1.59693765146508	0.144869582016078	0.493440661657659
GO:0005021	vascular endothelial growth factor receptor activity	7/1602	51/18639	0.137254901960784	1.59693765146508	0.144869582016078	0.493440661657659
GO:0005030	neurotrophin receptor activity	7/1602	51/18639	0.137254901960784	1.59693765146508	0.144869582016078	0.493440661657659
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/1602	24/18639	0.166666666666667	1.93913857677903	0.14611394282336	0.493440661657659
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/1602	24/18639	0.166666666666667	1.93913857677903	0.14611394282336	0.493440661657659
GO:0035035	histone acetyltransferase binding	4/1602	24/18639	0.166666666666667	1.93913857677903	0.14611394282336	0.493440661657659
GO:0070840	dynein complex binding	4/1602	24/18639	0.166666666666667	1.93913857677903	0.14611394282336	0.493440661657659
GO:0051879	Hsp90 protein binding	6/1602	42/18639	0.142857142857143	1.66211878009631	0.148134905703869	0.495831161691492
GO:0001664	G protein-coupled receptor binding	31/1602	297/18639	0.104377104377104	1.2144100177808	0.149855155591828	0.495831161691492
GO:0019905	syntaxin binding	8/1602	61/18639	0.131147540983607	1.52587953582612	0.150372882669583	0.495831161691492
GO:0005178	integrin binding	18/1602	161/18639	0.111801242236025	1.30078861051015	0.150567261331077	0.495831161691492
GO:0003688	DNA replication origin binding	3/1602	16/18639	0.1875	2.1815308988764	0.153383667884713	0.495831161691492
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	3/1602	16/18639	0.1875	2.1815308988764	0.153383667884713	0.495831161691492
GO:0004707	MAP kinase activity	3/1602	16/18639	0.1875	2.1815308988764	0.153383667884713	0.495831161691492
GO:0005159	insulin-like growth factor receptor binding	3/1602	16/18639	0.1875	2.1815308988764	0.153383667884713	0.495831161691492
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/1602	16/18639	0.1875	2.1815308988764	0.153383667884713	0.495831161691492
GO:0005521	lamin binding	3/1602	16/18639	0.1875	2.1815308988764	0.153383667884713	0.495831161691492
GO:0016675	oxidoreductase activity, acting on a heme group of donors	3/1602	16/18639	0.1875	2.1815308988764	0.153383667884713	0.495831161691492
GO:0016722	oxidoreductase activity, acting on metal ions	3/1602	16/18639	0.1875	2.1815308988764	0.153383667884713	0.495831161691492
GO:0030275	LRR domain binding	3/1602	16/18639	0.1875	2.1815308988764	0.153383667884713	0.495831161691492
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3/1602	16/18639	0.1875	2.1815308988764	0.153383667884713	0.495831161691492
GO:0034450	ubiquitin-ubiquitin ligase activity	3/1602	16/18639	0.1875	2.1815308988764	0.153383667884713	0.495831161691492
GO:0140328	floppase activity	3/1602	16/18639	0.1875	2.1815308988764	0.153383667884713	0.495831161691492
GO:0030159	signaling receptor complex adaptor activity	7/1602	52/18639	0.134615384615385	1.56622731201383	0.155804583437525	0.501667769682417
GO:0003697	single-stranded DNA binding	14/1602	121/18639	0.115702479338843	1.34617884668957	0.156019091315623	0.501667769682417
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	11/1602	91/18639	0.120879120879121	1.40640819854303	0.156810066008162	0.502873659957208
GO:0042974	nuclear retinoic acid receptor binding	4/1602	25/18639	0.16	1.86157303370787	0.162846450294774	0.518740804472126
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	14/1602	122/18639	0.114754098360656	1.33514459384785	0.163196881094569	0.518740804472126
GO:0005518	collagen binding	9/1602	72/18639	0.125	1.45435393258427	0.16327732700325	0.518740804472126
GO:0030332	cyclin binding	5/1602	34/18639	0.147058823529412	1.71100462656973	0.163474149300149	0.518740804472126
GO:0043022	ribosome binding	13/1602	112/18639	0.116071428571429	1.35047150882825	0.16428264260146	0.519941662055407
GO:0005003	ephrin receptor activity	7/1602	53/18639	0.132075471698113	1.53667585329659	0.167105132788249	0.520696148301528
GO:0005005	transmembrane-ephrin receptor activity	7/1602	53/18639	0.132075471698113	1.53667585329659	0.167105132788249	0.520696148301528
GO:0008146	sulfotransferase activity	7/1602	53/18639	0.132075471698113	1.53667585329659	0.167105132788249	0.520696148301528
GO:0017046	peptide hormone binding	7/1602	53/18639	0.132075471698113	1.53667585329659	0.167105132788249	0.520696148301528
GO:0034212	protein N-acetyltransferase activity	7/1602	53/18639	0.132075471698113	1.53667585329659	0.167105132788249	0.520696148301528
GO:0038064	collagen receptor activity	7/1602	53/18639	0.132075471698113	1.53667585329659	0.167105132788249	0.520696148301528
GO:1901682	sulfur compound transmembrane transporter activity	8/1602	63/18639	0.126984126984127	1.47743891564116	0.170964330716303	0.531351865902339
GO:0004722	protein serine/threonine phosphatase activity	12/1602	103/18639	0.116504854368932	1.35551434493291	0.173119979437218	0.53170774796053
GO:0001046	core promoter sequence-specific DNA binding	6/1602	44/18639	0.136363636363636	1.58656792645557	0.173227975446024	0.53170774796053
GO:0016790	thiolester hydrolase activity	6/1602	44/18639	0.136363636363636	1.58656792645557	0.173227975446024	0.53170774796053
GO:0019903	protein phosphatase binding	16/1602	144/18639	0.111111111111111	1.29275905118602	0.173788191497971	0.53170774796053
GO:0030165	PDZ domain binding	10/1602	83/18639	0.120481927710843	1.40178692297279	0.173832715807899	0.53170774796053
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	3/1602	17/18639	0.176470588235294	2.05320555188367	0.175036959212813	0.53170774796053
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/1602	17/18639	0.176470588235294	2.05320555188367	0.175036959212813	0.53170774796053
GO:0017110	nucleoside diphosphate phosphatase activity	3/1602	17/18639	0.176470588235294	2.05320555188367	0.175036959212813	0.53170774796053
GO:0019198	transmembrane receptor protein phosphatase activity	3/1602	17/18639	0.176470588235294	2.05320555188367	0.175036959212813	0.53170774796053
GO:0005516	calmodulin binding	22/1602	207/18639	0.106280193236715	1.23655213591706	0.175969670042344	0.533201331030561
GO:0010485	histone H4 acetyltransferase activity	5/1602	35/18639	0.142857142857143	1.66211878009631	0.178152319127731	0.537598153514758
GO:0017069	snRNA binding	7/1602	54/18639	0.12962962962963	1.50821889305035	0.178754721019796	0.537598153514758
GO:0140463	chromatin-protein adaptor activity	7/1602	54/18639	0.12962962962963	1.50821889305035	0.178754721019796	0.537598153514758
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/1602	26/18639	0.153846153846154	1.78997407087295	0.180228305297215	0.538014866924278
GO:0004435	phosphatidylinositol phospholipase C activity	4/1602	26/18639	0.153846153846154	1.78997407087295	0.180228305297215	0.538014866924278
GO:0050681	nuclear androgen receptor binding	4/1602	26/18639	0.153846153846154	1.78997407087295	0.180228305297215	0.538014866924278
GO:0004536	DNA nuclease activity	8/1602	64/18639	0.125	1.45435393258427	0.18171240883974	0.541109118934103
GO:0004715	non-membrane spanning protein tyrosine kinase activity	6/1602	45/18639	0.133333333333333	1.55131086142322	0.186387308136326	0.550959059992221
GO:0008009	chemokine activity	6/1602	45/18639	0.133333333333333	1.55131086142322	0.186387308136326	0.550959059992221
GO:0042605	peptide antigen binding	6/1602	45/18639	0.133333333333333	1.55131086142322	0.186387308136326	0.550959059992221
GO:0019838	growth factor binding	15/1602	136/18639	0.110294117647059	1.2832534699273	0.190766794090182	0.56116071546236
GO:0140789	histone phosphatase activity	15/1602	136/18639	0.110294117647059	1.2832534699273	0.190766794090182	0.56116071546236
GO:0160215	deacylase activity	8/1602	65/18639	0.123076923076923	1.43197925669836	0.192744818308515	0.565603119745132
GO:0004706	JUN kinase kinase kinase activity	3/1602	18/18639	0.166666666666667	1.93913857677903	0.197470165924338	0.570432105043465
GO:0015172	acidic amino acid transmembrane transporter activity	3/1602	18/18639	0.166666666666667	1.93913857677903	0.197470165924338	0.570432105043465
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/1602	18/18639	0.166666666666667	1.93913857677903	0.197470165924338	0.570432105043465
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	3/1602	18/18639	0.166666666666667	1.93913857677903	0.197470165924338	0.570432105043465
GO:0070064	proline-rich region binding	3/1602	18/18639	0.166666666666667	1.93913857677903	0.197470165924338	0.570432105043465
GO:0008266	poly(U) RNA binding	4/1602	27/18639	0.148148148148148	1.72367873491469	0.198190409470618	0.570432105043465
GO:0023026	MHC class II protein complex binding	4/1602	27/18639	0.148148148148148	1.72367873491469	0.198190409470618	0.570432105043465
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	4/1602	27/18639	0.148148148148148	1.72367873491469	0.198190409470618	0.570432105043465
GO:0000149	SNARE binding	12/1602	106/18639	0.113207547169811	1.31715073139707	0.198636820697517	0.570432105043465
GO:0019213	deacetylase activity	5/1602	37/18639	0.135135135135135	1.57227452171272	0.208882005692822	0.581180381268417
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	14/1602	128/18639	0.109375	1.27255969101124	0.209643208377425	0.581180381268417
GO:0005131	growth hormone receptor binding	2/1602	10/18639	0.2	2.32696629213483	0.210070989755416	0.581180381268417
GO:0008239	dipeptidyl-peptidase activity	2/1602	10/18639	0.2	2.32696629213483	0.210070989755416	0.581180381268417
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/1602	10/18639	0.2	2.32696629213483	0.210070989755416	0.581180381268417
GO:0016427	tRNA (cytidine) methyltransferase activity	2/1602	10/18639	0.2	2.32696629213483	0.210070989755416	0.581180381268417
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/1602	10/18639	0.2	2.32696629213483	0.210070989755416	0.581180381268417
GO:0042975	peroxisome proliferator activated receptor binding	2/1602	10/18639	0.2	2.32696629213483	0.210070989755416	0.581180381268417
GO:0043422	protein kinase B binding	2/1602	10/18639	0.2	2.32696629213483	0.210070989755416	0.581180381268417
GO:0047429	nucleoside triphosphate diphosphatase activity	2/1602	10/18639	0.2	2.32696629213483	0.210070989755416	0.581180381268417
GO:0050815	phosphoserine residue binding	2/1602	10/18639	0.2	2.32696629213483	0.210070989755416	0.581180381268417
GO:0070097	delta-catenin binding	2/1602	10/18639	0.2	2.32696629213483	0.210070989755416	0.581180381268417
GO:0099122	RNA polymerase II C-terminal domain binding	2/1602	10/18639	0.2	2.32696629213483	0.210070989755416	0.581180381268417
GO:0140940	histone H2A methyltransferase activity	2/1602	10/18639	0.2	2.32696629213483	0.210070989755416	0.581180381268417
GO:0140999	histone H3K4 trimethyltransferase activity	2/1602	10/18639	0.2	2.32696629213483	0.210070989755416	0.581180381268417
GO:1990259	histone H2AQ104 methyltransferase activity	2/1602	10/18639	0.2	2.32696629213483	0.210070989755416	0.581180381268417
GO:0061749	forked DNA-dependent helicase activity	6/1602	47/18639	0.127659574468085	1.48529763327755	0.213801445116375	0.586007440804323
GO:1990518	single-stranded 3'-5' DNA helicase activity	6/1602	47/18639	0.127659574468085	1.48529763327755	0.213801445116375	0.586007440804323
GO:0016500	protein-hormone receptor activity	8/1602	67/18639	0.119402985074627	1.38923360724468	0.215606394318311	0.586007440804323
GO:0050840	extracellular matrix binding	8/1602	67/18639	0.119402985074627	1.38923360724468	0.215606394318311	0.586007440804323
GO:0015932	nucleobase-containing compound transmembrane transporter activity	7/1602	57/18639	0.12280701754386	1.42883895131086	0.215616958210718	0.586007440804323
GO:0004843	cysteine-type deubiquitinase activity	12/1602	108/18639	0.111111111111111	1.29275905118602	0.2165290268808	0.586007440804323
GO:0046966	nuclear thyroid hormone receptor binding	4/1602	28/18639	0.142857142857143	1.66211878009631	0.216662800694402	0.586007440804323
GO:0051019	mitogen-activated protein kinase binding	4/1602	28/18639	0.142857142857143	1.66211878009631	0.216662800694402	0.586007440804323
GO:0097718	disordered domain specific binding	4/1602	28/18639	0.142857142857143	1.66211878009631	0.216662800694402	0.586007440804323
GO:0141052	histone H3 demethylase activity	4/1602	28/18639	0.142857142857143	1.66211878009631	0.216662800694402	0.586007440804323
GO:0004725	protein tyrosine phosphatase activity	11/1602	98/18639	0.112244897959184	1.30595047007567	0.219773026743786	0.591204676909787
GO:0042626	ATPase-coupled transmembrane transporter activity	11/1602	98/18639	0.112244897959184	1.30595047007567	0.219773026743786	0.591204676909787
GO:0015245	fatty acid transmembrane transporter activity	3/1602	19/18639	0.157894736842105	1.83707865168539	0.220540371618126	0.591204676909787
GO:0030506	ankyrin binding	3/1602	19/18639	0.157894736842105	1.83707865168539	0.220540371618126	0.591204676909787
GO:0008201	heparin binding	18/1602	172/18639	0.104651162790698	1.21759864123334	0.223765007409283	0.59852188928722
GO:0004620	phospholipase activity	12/1602	109/18639	0.110091743119266	1.28089887640449	0.225720485379416	0.59919612423033
GO:0016298	lipase activity	14/1602	130/18639	0.107692307692308	1.25298184961106	0.226313459612237	0.59919612423033
GO:0016798	hydrolase activity, acting on glycosyl bonds	14/1602	130/18639	0.107692307692308	1.25298184961106	0.226313459612237	0.59919612423033
GO:0005548	phospholipid transporter activity	8/1602	68/18639	0.117647058823529	1.36880370125578	0.22740583333893	0.59919612423033
GO:0030145	manganese ion binding	8/1602	68/18639	0.117647058823529	1.36880370125578	0.22740583333893	0.59919612423033
GO:0009378	four-way junction helicase activity	6/1602	48/18639	0.125	1.45435393258427	0.228001085536762	0.59919612423033
GO:0036121	double-stranded DNA helicase activity	6/1602	48/18639	0.125	1.45435393258427	0.228001085536762	0.59919612423033
GO:0043138	3'-5' DNA helicase activity	6/1602	48/18639	0.125	1.45435393258427	0.228001085536762	0.59919612423033
GO:0017116	single-stranded DNA helicase activity	7/1602	58/18639	0.120689655172414	1.40420379697792	0.228477595756974	0.59919612423033
GO:0099604	ligand-gated calcium channel activity	4/1602	29/18639	0.137931034482759	1.60480433940333	0.235575448425157	0.609771834327132
GO:0004016	adenylate cyclase activity	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0004143	ATP-dependent diacylglycerol kinase activity	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0005536	D-glucose binding	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0008432	JUN kinase binding	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0016176	superoxide-generating NADPH oxidase activator activity	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0019215	intermediate filament binding	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0034056	estrogen response element binding	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0050998	nitric-oxide synthase binding	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0070990	snRNP binding	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0140537	transcription regulator activator activity	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0180030	inositol phosphate kinase activity	2/1602	11/18639	0.181818181818182	2.11542390194076	0.242979421212385	0.609771834327132
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	3/1602	20/18639	0.15	1.74522471910112	0.244110477927487	0.609771834327132
GO:0030742	GTP-dependent protein binding	3/1602	20/18639	0.15	1.74522471910112	0.244110477927487	0.609771834327132
GO:0031418	L-ascorbic acid binding	3/1602	20/18639	0.15	1.74522471910112	0.244110477927487	0.609771834327132
GO:0061608	nuclear import signal receptor activity	3/1602	20/18639	0.15	1.74522471910112	0.244110477927487	0.609771834327132
GO:0005085	guanyl-nucleotide exchange factor activity	23/1602	230/18639	0.1	1.16348314606742	0.25294793267804	0.630544434242785
GO:0031624	ubiquitin conjugating enzyme binding	4/1602	30/18639	0.133333333333333	1.55131086142322	0.254858953845469	0.632888905870841
GO:0004714	transmembrane receptor protein tyrosine kinase activity	7/1602	60/18639	0.116666666666667	1.35739700374532	0.254935398808188	0.632888905870841
GO:0015605	organophosphate ester transmembrane transporter activity	6/1602	50/18639	0.12	1.3961797752809	0.257242318870264	0.63333582066485
GO:0030331	nuclear estrogen receptor binding	5/1602	40/18639	0.125	1.45435393258427	0.257785264077142	0.63333582066485
GO:0032451	demethylase activity	5/1602	40/18639	0.125	1.45435393258427	0.257785264077142	0.63333582066485
GO:0061791	GTPase motor activity	5/1602	40/18639	0.125	1.45435393258427	0.257785264077142	0.63333582066485
GO:1990606	membrane scission GTPase motor activity	5/1602	40/18639	0.125	1.45435393258427	0.257785264077142	0.63333582066485
GO:0005539	glycosaminoglycan binding	24/1602	242/18639	0.0991735537190083	1.15386758287678	0.260322784736897	0.63333582066485
GO:0046943	carboxylic acid transmembrane transporter activity	19/1602	188/18639	0.101063829787234	1.17586062634473	0.262876093654478	0.63333582066485
GO:0008194	UDP-glycosyltransferase activity	15/1602	145/18639	0.103448275862069	1.2036032545525	0.263819549834989	0.63333582066485
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	3/1602	21/18639	0.142857142857143	1.66211878009631	0.268050372621994	0.63333582066485
GO:0008373	sialyltransferase activity	3/1602	21/18639	0.142857142857143	1.66211878009631	0.268050372621994	0.63333582066485
GO:0009931	calcium-dependent protein serine/threonine kinase activity	3/1602	21/18639	0.142857142857143	1.66211878009631	0.268050372621994	0.63333582066485
GO:0035613	RNA stem-loop binding	3/1602	21/18639	0.142857142857143	1.66211878009631	0.268050372621994	0.63333582066485
GO:0072542	protein phosphatase activator activity	3/1602	21/18639	0.142857142857143	1.66211878009631	0.268050372621994	0.63333582066485
GO:0140312	cargo adaptor activity	3/1602	21/18639	0.142857142857143	1.66211878009631	0.268050372621994	0.63333582066485
GO:0005342	organic acid transmembrane transporter activity	19/1602	189/18639	0.100529100529101	1.16963914154925	0.270470851895053	0.63333582066485
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	9/1602	82/18639	0.109756097560976	1.27699369690326	0.271018430456173	0.63333582066485
GO:0005048	signal sequence binding	6/1602	51/18639	0.117647058823529	1.36880370125578	0.272225350450823	0.63333582066485
GO:0016411	acylglycerol O-acyltransferase activity	4/1602	31/18639	0.129032258064516	1.50126857557086	0.274445158292835	0.63333582066485
GO:0001727	lipid kinase activity	5/1602	41/18639	0.121951219512195	1.41888188544807	0.274665273919243	0.63333582066485
GO:0000995	RNA polymerase III general transcription initiation factor activity	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0004000	adenosine deaminase activity	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0004300	enoyl-CoA hydratase activity	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0005025	transforming growth factor beta receptor activity, type I	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0005026	transforming growth factor beta receptor activity, type II	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0005078	MAP-kinase scaffold activity	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0005165	neurotrophin receptor binding	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0005247	voltage-gated chloride channel activity	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0015368	calcium:monoatomic cation antiporter activity	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0016361	activin receptor activity, type I	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0016362	activin receptor activity, type II	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0017002	activin receptor activity	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0031543	peptidyl-proline dioxygenase activity	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0035251	UDP-glucosyltransferase activity	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0035259	nuclear glucocorticoid receptor binding	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0035497	cAMP response element binding	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0036009	protein-glutamine N-methyltransferase activity	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0042301	phosphate ion binding	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:1990459	transferrin receptor binding	2/1602	12/18639	0.166666666666667	1.93913857677903	0.276069460289806	0.63333582066485
GO:0042379	chemokine receptor binding	8/1602	72/18639	0.111111111111111	1.29275905118602	0.276691067059719	0.633559659233335
GO:0001540	amyloid-beta binding	9/1602	83/18639	0.108433734939759	1.26160823067551	0.282838314670153	0.645191551766443
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	9/1602	83/18639	0.108433734939759	1.26160823067551	0.282838314670153	0.645191551766443
GO:0101005	deubiquitinase activity	12/1602	115/18639	0.104347826086957	1.21406936980948	0.283855830125798	0.646293217744049
GO:0043539	protein serine/threonine kinase activator activity	8/1602	73/18639	0.10958904109589	1.27505002308758	0.289451316865891	0.654287871486952
GO:0019894	kinesin binding	5/1602	42/18639	0.119047619047619	1.38509898341359	0.291763972326726	0.654287871486952
GO:0042056	chemoattractant activity	5/1602	42/18639	0.119047619047619	1.38509898341359	0.291763972326726	0.654287871486952
GO:0048487	beta-tubulin binding	5/1602	42/18639	0.119047619047619	1.38509898341359	0.291763972326726	0.654287871486952
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/1602	22/18639	0.136363636363636	1.58656792645557	0.292237758976802	0.654287871486952
GO:0034062	5'-3' RNA polymerase activity	3/1602	22/18639	0.136363636363636	1.58656792645557	0.292237758976802	0.654287871486952
GO:0050321	tau-protein kinase activity	3/1602	22/18639	0.136363636363636	1.58656792645557	0.292237758976802	0.654287871486952
GO:0070034	telomerase RNA binding	3/1602	22/18639	0.136363636363636	1.58656792645557	0.292237758976802	0.654287871486952
GO:0097747	RNA polymerase activity	3/1602	22/18639	0.136363636363636	1.58656792645557	0.292237758976802	0.654287871486952
GO:0031369	translation initiation factor binding	4/1602	32/18639	0.125	1.45435393258427	0.294267664486677	0.655162509018988
GO:0120015	sterol transfer activity	4/1602	32/18639	0.125	1.45435393258427	0.294267664486677	0.655162509018988
GO:0140142	nucleocytoplasmic carrier activity	4/1602	32/18639	0.125	1.45435393258427	0.294267664486677	0.655162509018988
GO:0051117	ATPase binding	9/1602	84/18639	0.107142857142857	1.24658908507223	0.294796033834846	0.655162509018988
GO:0003678	DNA helicase activity	8/1602	74/18639	0.108108108108108	1.25781961737018	0.302353190328669	0.667253495131453
GO:0031491	nucleosome binding	8/1602	74/18639	0.108108108108108	1.25781961737018	0.302353190328669	0.667253495131453
GO:0005246	calcium channel regulator activity	6/1602	53/18639	0.113207547169811	1.31715073139707	0.302768821304245	0.667253495131453
GO:0051018	protein kinase A binding	6/1602	53/18639	0.113207547169811	1.31715073139707	0.302768821304245	0.667253495131453
GO:0031490	chromatin DNA binding	13/1602	128/18639	0.1015625	1.18166257022472	0.305940663731642	0.667253495131453
GO:0002161	aminoacyl-tRNA editing activity	2/1602	13/18639	0.153846153846154	1.78997407087295	0.309066962178341	0.667253495131453
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/1602	13/18639	0.153846153846154	1.78997407087295	0.309066962178341	0.667253495131453
GO:0004465	lipoprotein lipase activity	2/1602	13/18639	0.153846153846154	1.78997407087295	0.309066962178341	0.667253495131453
GO:0005338	nucleotide-sugar transmembrane transporter activity	2/1602	13/18639	0.153846153846154	1.78997407087295	0.309066962178341	0.667253495131453
GO:0008253	5'-nucleotidase activity	2/1602	13/18639	0.153846153846154	1.78997407087295	0.309066962178341	0.667253495131453
GO:0008417	fucosyltransferase activity	2/1602	13/18639	0.153846153846154	1.78997407087295	0.309066962178341	0.667253495131453
GO:0035325	Toll-like receptor binding	2/1602	13/18639	0.153846153846154	1.78997407087295	0.309066962178341	0.667253495131453
GO:0039706	co-receptor binding	2/1602	13/18639	0.153846153846154	1.78997407087295	0.309066962178341	0.667253495131453
GO:0070123	transforming growth factor beta receptor activity, type III	2/1602	13/18639	0.153846153846154	1.78997407087295	0.309066962178341	0.667253495131453
GO:0097157	pre-mRNA intronic binding	2/1602	13/18639	0.153846153846154	1.78997407087295	0.309066962178341	0.667253495131453
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/1602	13/18639	0.153846153846154	1.78997407087295	0.309066962178341	0.667253495131453
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	45/1602	484/18639	0.0929752066115702	1.08175085894698	0.310949677651751	0.670121497827037
GO:0019888	protein phosphatase regulator activity	11/1602	107/18639	0.102803738317757	1.19610416885435	0.312681638745407	0.672654984418499
GO:0003887	DNA-directed DNA polymerase activity	3/1602	23/18639	0.130434782608696	1.51758671226185	0.31655870408529	0.673801889505486
GO:0031681	G-protein beta-subunit binding	3/1602	23/18639	0.130434782608696	1.51758671226185	0.31655870408529	0.673801889505486
GO:0042171	lysophosphatidic acid acyltransferase activity	3/1602	23/18639	0.130434782608696	1.51758671226185	0.31655870408529	0.673801889505486
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	3/1602	23/18639	0.130434782608696	1.51758671226185	0.31655870408529	0.673801889505486
GO:0070577	lysine-acetylated histone binding	3/1602	23/18639	0.130434782608696	1.51758671226185	0.31655870408529	0.673801889505486
GO:0071617	lysophospholipid acyltransferase activity	3/1602	23/18639	0.130434782608696	1.51758671226185	0.31655870408529	0.673801889505486
GO:0050661	NADP binding	6/1602	54/18639	0.111111111111111	1.29275905118602	0.318270583839801	0.675068659407578
GO:0051287	NAD binding	6/1602	54/18639	0.111111111111111	1.29275905118602	0.318270583839801	0.675068659407578
GO:0005543	phospholipid binding	46/1602	497/18639	0.0925553319919517	1.0768656885131	0.319793954388231	0.677111892916587
GO:0120013	lipid transfer activity	7/1602	65/18639	0.107692307692308	1.25298184961106	0.324368105852419	0.685596223733523
GO:0008175	tRNA methyltransferase activity	4/1602	34/18639	0.117647058823529	1.36880370125578	0.334367359339049	0.699099672390295
GO:0008376	acetylgalactosaminyltransferase activity	4/1602	34/18639	0.117647058823529	1.36880370125578	0.334367359339049	0.699099672390295
GO:0042625	ATPase-coupled ion transmembrane transporter activity	3/1602	24/18639	0.125	1.45435393258427	0.340907955694137	0.699099672390295
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	3/1602	24/18639	0.125	1.45435393258427	0.340907955694137	0.699099672390295
GO:0046961	proton-transporting ATPase activity, rotational mechanism	3/1602	24/18639	0.125	1.45435393258427	0.340907955694137	0.699099672390295
GO:0048027	mRNA 5'-UTR binding	3/1602	24/18639	0.125	1.45435393258427	0.340907955694137	0.699099672390295
GO:0050431	transforming growth factor beta binding	3/1602	24/18639	0.125	1.45435393258427	0.340907955694137	0.699099672390295
GO:0140033	acetylation-dependent protein binding	3/1602	24/18639	0.125	1.45435393258427	0.340907955694137	0.699099672390295
GO:0004705	JUN kinase activity	2/1602	14/18639	0.142857142857143	1.66211878009631	0.341743512309896	0.699099672390295
GO:0008195	phosphatidate phosphatase activity	2/1602	14/18639	0.142857142857143	1.66211878009631	0.341743512309896	0.699099672390295
GO:0015926	glucosidase activity	2/1602	14/18639	0.142857142857143	1.66211878009631	0.341743512309896	0.699099672390295
GO:0016530	metallochaperone activity	2/1602	14/18639	0.142857142857143	1.66211878009631	0.341743512309896	0.699099672390295
GO:0030983	mismatched DNA binding	2/1602	14/18639	0.142857142857143	1.66211878009631	0.341743512309896	0.699099672390295
GO:0042813	Wnt receptor activity	2/1602	14/18639	0.142857142857143	1.66211878009631	0.341743512309896	0.699099672390295
GO:0044548	S100 protein binding	2/1602	14/18639	0.142857142857143	1.66211878009631	0.341743512309896	0.699099672390295
GO:0061665	SUMO ligase activity	2/1602	14/18639	0.142857142857143	1.66211878009631	0.341743512309896	0.699099672390295
GO:0071933	Arp2/3 complex binding	2/1602	14/18639	0.142857142857143	1.66211878009631	0.341743512309896	0.699099672390295
GO:0098821	BMP receptor activity	2/1602	14/18639	0.142857142857143	1.66211878009631	0.341743512309896	0.699099672390295
GO:1901612	cardiolipin binding	2/1602	14/18639	0.142857142857143	1.66211878009631	0.341743512309896	0.699099672390295
GO:0046915	transition metal ion transmembrane transporter activity	5/1602	45/18639	0.111111111111111	1.29275905118602	0.343959399058979	0.702444110578219
GO:0001216	DNA-binding transcription activator activity	45/1602	491/18639	0.0916496945010183	1.06632874894162	0.347019668646362	0.707498784811891
GO:0045296	cadherin binding	31/1602	334/18639	0.092814371257485	1.07987956670928	0.353447805105294	0.718273539402706
GO:0015399	primary active transmembrane transporter activity	16/1602	166/18639	0.0963855421686747	1.12142953837823	0.353492767530695	0.718273539402706
GO:0140566	histone reader activity	4/1602	35/18639	0.114285714285714	1.32969502407705	0.354524138721156	0.71916054314409
GO:0004180	carboxypeptidase activity	5/1602	46/18639	0.108695652173913	1.26465559355154	0.361525076089678	0.730909392963915
GO:0030276	clathrin binding	5/1602	46/18639	0.108695652173913	1.26465559355154	0.361525076089678	0.730909392963915
GO:0004709	MAP kinase kinase kinase activity	3/1602	25/18639	0.12	1.3961797752809	0.365189070066778	0.731307934484702
GO:0008483	transaminase activity	3/1602	25/18639	0.12	1.3961797752809	0.365189070066778	0.731307934484702
GO:0019211	phosphatase activator activity	3/1602	25/18639	0.12	1.3961797752809	0.365189070066778	0.731307934484702
GO:0047617	fatty acyl-CoA hydrolase activity	3/1602	25/18639	0.12	1.3961797752809	0.365189070066778	0.731307934484702
GO:0120020	cholesterol transfer activity	3/1602	25/18639	0.12	1.3961797752809	0.365189070066778	0.731307934484702
GO:0070279	vitamin B6 binding	6/1602	57/18639	0.105263157894737	1.2247191011236	0.365351523927841	0.731307934484702
GO:0019210	kinase inhibitor activity	9/1602	90/18639	0.1	1.16348314606742	0.368661523661177	0.731485296904564
GO:0000774	adenyl-nucleotide exchange factor activity	2/1602	15/18639	0.133333333333333	1.55131086142322	0.373910598417718	0.731485296904564
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/1602	15/18639	0.133333333333333	1.55131086142322	0.373910598417718	0.731485296904564
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/1602	15/18639	0.133333333333333	1.55131086142322	0.373910598417718	0.731485296904564
GO:0005041	low-density lipoprotein particle receptor activity	2/1602	15/18639	0.133333333333333	1.55131086142322	0.373910598417718	0.731485296904564
GO:0008242	omega peptidase activity	2/1602	15/18639	0.133333333333333	1.55131086142322	0.373910598417718	0.731485296904564
GO:0008252	nucleotidase activity	2/1602	15/18639	0.133333333333333	1.55131086142322	0.373910598417718	0.731485296904564
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/1602	15/18639	0.133333333333333	1.55131086142322	0.373910598417718	0.731485296904564
GO:0016846	carbon-sulfur lyase activity	2/1602	15/18639	0.133333333333333	1.55131086142322	0.373910598417718	0.731485296904564
GO:0033130	acetylcholine receptor binding	2/1602	15/18639	0.133333333333333	1.55131086142322	0.373910598417718	0.731485296904564
GO:0050780	dopamine receptor binding	2/1602	15/18639	0.133333333333333	1.55131086142322	0.373910598417718	0.731485296904564
GO:0061578	K63-linked deubiquitinase activity	2/1602	15/18639	0.133333333333333	1.55131086142322	0.373910598417718	0.731485296904564
GO:0120283	protein serine/threonine kinase binding	2/1602	15/18639	0.133333333333333	1.55131086142322	0.373910598417718	0.731485296904564
GO:0140776	protein-containing complex destabilizing activity	2/1602	15/18639	0.133333333333333	1.55131086142322	0.373910598417718	0.731485296904564
GO:0044390	ubiquitin-like protein conjugating enzyme binding	4/1602	36/18639	0.111111111111111	1.29275905118602	0.374676922826763	0.731800322613177
GO:0015297	antiporter activity	13/1602	135/18639	0.0962962962962963	1.12039117769455	0.376381561403566	0.733944044736953
GO:0048306	calcium-dependent protein binding	8/1602	80/18639	0.1	1.16348314606742	0.381781019046856	0.743274157854507
GO:0008143	poly(A) binding	3/1602	26/18639	0.115384615384615	1.34248055315471	0.389314387210635	0.749492188117289
GO:0008198	ferrous iron binding	3/1602	26/18639	0.115384615384615	1.34248055315471	0.389314387210635	0.749492188117289
GO:0015216	purine nucleotide transmembrane transporter activity	3/1602	26/18639	0.115384615384615	1.34248055315471	0.389314387210635	0.749492188117289
GO:0016289	acyl-CoA hydrolase activity	3/1602	26/18639	0.115384615384615	1.34248055315471	0.389314387210635	0.749492188117289
GO:0030247	polysaccharide binding	3/1602	26/18639	0.115384615384615	1.34248055315471	0.389314387210635	0.749492188117289
GO:0030507	spectrin binding	3/1602	26/18639	0.115384615384615	1.34248055315471	0.389314387210635	0.749492188117289
GO:0052742	phosphatidylinositol kinase activity	3/1602	26/18639	0.115384615384615	1.34248055315471	0.389314387210635	0.749492188117289
GO:0023023	MHC protein complex binding	4/1602	37/18639	0.108108108108108	1.25781961737018	0.394773276418756	0.750069885246856
GO:0033192	calmodulin-dependent protein phosphatase activity	8/1602	81/18639	0.0987654320987654	1.14911915660979	0.395198111581677	0.750069885246856
GO:0140791	histone H2AXS140 phosphatase activity	8/1602	81/18639	0.0987654320987654	1.14911915660979	0.395198111581677	0.750069885246856
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	8/1602	81/18639	0.0987654320987654	1.14911915660979	0.395198111581677	0.750069885246856
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	8/1602	81/18639	0.0987654320987654	1.14911915660979	0.395198111581677	0.750069885246856
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	8/1602	81/18639	0.0987654320987654	1.14911915660979	0.395198111581677	0.750069885246856
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	8/1602	81/18639	0.0987654320987654	1.14911915660979	0.395198111581677	0.750069885246856
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	8/1602	81/18639	0.0987654320987654	1.14911915660979	0.395198111581677	0.750069885246856
GO:1990439	MAP kinase serine/threonine phosphatase activity	8/1602	81/18639	0.0987654320987654	1.14911915660979	0.395198111581677	0.750069885246856
GO:0140693	molecular condensate scaffold activity	5/1602	48/18639	0.104166666666667	1.21196161048689	0.396682168808231	0.751706492302745
GO:0000062	fatty-acyl-CoA binding	2/1602	16/18639	0.125	1.45435393258427	0.405414445636719	0.761096373873902
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/1602	16/18639	0.125	1.45435393258427	0.405414445636719	0.761096373873902
GO:0005149	interleukin-1 receptor binding	2/1602	16/18639	0.125	1.45435393258427	0.405414445636719	0.761096373873902
GO:0008142	oxysterol binding	2/1602	16/18639	0.125	1.45435393258427	0.405414445636719	0.761096373873902
GO:0022858	alanine transmembrane transporter activity	2/1602	16/18639	0.125	1.45435393258427	0.405414445636719	0.761096373873902
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	2/1602	16/18639	0.125	1.45435393258427	0.405414445636719	0.761096373873902
GO:0003924	GTPase activity	30/1602	331/18639	0.0906344410876133	1.05451644658678	0.407850707694356	0.764482954422444
GO:0033549	MAP kinase phosphatase activity	8/1602	82/18639	0.0975609756097561	1.13510550835845	0.408622941973624	0.76474479387943
GO:0042826	histone deacetylase binding	12/1602	127/18639	0.094488188976378	1.09935415376449	0.410029166156725	0.766190512957466
GO:0004364	glutathione transferase activity	3/1602	27/18639	0.111111111111111	1.29275905118602	0.413204884428137	0.767917065326924
GO:0004683	calcium/calmodulin-dependent protein kinase activity	3/1602	27/18639	0.111111111111111	1.29275905118602	0.413204884428137	0.767917065326924
GO:0008320	protein transmembrane transporter activity	3/1602	27/18639	0.111111111111111	1.29275905118602	0.413204884428137	0.767917065326924
GO:0005109	frizzled binding	4/1602	38/18639	0.105263157894737	1.2247191011236	0.414764138675336	0.767917065326924
GO:0005501	retinoid binding	4/1602	38/18639	0.105263157894737	1.2247191011236	0.414764138675336	0.767917065326924
GO:0019840	isoprenoid binding	4/1602	38/18639	0.105263157894737	1.2247191011236	0.414764138675336	0.767917065326924
GO:0019208	phosphatase regulator activity	11/1602	117/18639	0.094017094017094	1.09387304331125	0.424193071452353	0.782976218909762
GO:1990782	protein tyrosine kinase binding	11/1602	117/18639	0.094017094017094	1.09387304331125	0.424193071452353	0.782976218909762
GO:0046982	protein heterodimerization activity	33/1602	369/18639	0.0894308943089431	1.04051338266192	0.431897692210853	0.784664235931214
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	4/1602	39/18639	0.102564102564103	1.19331604724863	0.434603895333655	0.784664235931214
GO:0004860	protein kinase inhibitor activity	8/1602	84/18639	0.0952380952380952	1.10807918673087	0.435434067312431	0.784664235931214
GO:0017018	myosin phosphatase activity	8/1602	84/18639	0.0952380952380952	1.10807918673087	0.435434067312431	0.784664235931214
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/1602	17/18639	0.117647058823529	1.36880370125578	0.436131443826573	0.784664235931214
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/1602	17/18639	0.117647058823529	1.36880370125578	0.436131443826573	0.784664235931214
GO:0008484	sulfuric ester hydrolase activity	2/1602	17/18639	0.117647058823529	1.36880370125578	0.436131443826573	0.784664235931214
GO:0008569	minus-end-directed microtubule motor activity	2/1602	17/18639	0.117647058823529	1.36880370125578	0.436131443826573	0.784664235931214
GO:0015278	intracellularly gated calcium channel activity	2/1602	17/18639	0.117647058823529	1.36880370125578	0.436131443826573	0.784664235931214
GO:0016805	dipeptidase activity	2/1602	17/18639	0.117647058823529	1.36880370125578	0.436131443826573	0.784664235931214
GO:0032183	SUMO binding	2/1602	17/18639	0.117647058823529	1.36880370125578	0.436131443826573	0.784664235931214
GO:0036041	long-chain fatty acid binding	2/1602	17/18639	0.117647058823529	1.36880370125578	0.436131443826573	0.784664235931214
GO:0038191	neuropilin binding	2/1602	17/18639	0.117647058823529	1.36880370125578	0.436131443826573	0.784664235931214
GO:1901567	fatty acid derivative binding	2/1602	17/18639	0.117647058823529	1.36880370125578	0.436131443826573	0.784664235931214
GO:0045499	chemorepellent activity	3/1602	28/18639	0.107142857142857	1.24658908507223	0.436789934476185	0.784664235931214
GO:0046875	ephrin receptor binding	3/1602	28/18639	0.107142857142857	1.24658908507223	0.436789934476185	0.784664235931214
GO:0051393	alpha-actinin binding	3/1602	28/18639	0.107142857142857	1.24658908507223	0.436789934476185	0.784664235931214
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	3/1602	28/18639	0.107142857142857	1.24658908507223	0.436789934476185	0.784664235931214
GO:0003743	translation initiation factor activity	5/1602	51/18639	0.0980392156862745	1.14066975104649	0.448972176067592	0.80296946873627
GO:0016830	carbon-carbon lyase activity	5/1602	51/18639	0.0980392156862745	1.14066975104649	0.448972176067592	0.80296946873627
GO:0030544	Hsp70 protein binding	5/1602	51/18639	0.0980392156862745	1.14066975104649	0.448972176067592	0.80296946873627
GO:0048029	monosaccharide binding	7/1602	74/18639	0.0945945945945946	1.10059216519891	0.453973172509209	0.808819949323289
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	4/1602	40/18639	0.1	1.16348314606742	0.454250409917712	0.808819949323289
GO:0050997	quaternary ammonium group binding	4/1602	40/18639	0.1	1.16348314606742	0.454250409917712	0.808819949323289
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	3/1602	29/18639	0.103448275862069	1.2036032545525	0.460006990558995	0.812084900289361
GO:0035250	UDP-galactosyltransferase activity	3/1602	29/18639	0.103448275862069	1.2036032545525	0.460006990558995	0.812084900289361
GO:0097472	cyclin-dependent protein kinase activity	3/1602	29/18639	0.103448275862069	1.2036032545525	0.460006990558995	0.812084900289361
GO:0016209	antioxidant activity	8/1602	86/18639	0.0930232558139535	1.08230990331853	0.46209526572321	0.812084900289361
GO:0000400	four-way junction DNA binding	2/1602	18/18639	0.111111111111111	1.29275905118602	0.465964103564352	0.812084900289361
GO:0000900	mRNA regulatory element binding translation repressor activity	2/1602	18/18639	0.111111111111111	1.29275905118602	0.465964103564352	0.812084900289361
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/1602	18/18639	0.111111111111111	1.29275905118602	0.465964103564352	0.812084900289361
GO:0008308	voltage-gated monoatomic anion channel activity	2/1602	18/18639	0.111111111111111	1.29275905118602	0.465964103564352	0.812084900289361
GO:0016854	racemase and epimerase activity	2/1602	18/18639	0.111111111111111	1.29275905118602	0.465964103564352	0.812084900289361
GO:0017075	syntaxin-1 binding	2/1602	18/18639	0.111111111111111	1.29275905118602	0.465964103564352	0.812084900289361
GO:0030228	lipoprotein particle receptor activity	2/1602	18/18639	0.111111111111111	1.29275905118602	0.465964103564352	0.812084900289361
GO:0031690	adrenergic receptor binding	2/1602	18/18639	0.111111111111111	1.29275905118602	0.465964103564352	0.812084900289361
GO:0035615	clathrin adaptor activity	2/1602	18/18639	0.111111111111111	1.29275905118602	0.465964103564352	0.812084900289361
GO:1901611	phosphatidylglycerol binding	2/1602	18/18639	0.111111111111111	1.29275905118602	0.465964103564352	0.812084900289361
GO:0005080	protein kinase C binding	5/1602	52/18639	0.0961538461538462	1.11873379429559	0.466159570554852	0.812084900289361
GO:0004540	RNA nuclease activity	11/1602	121/18639	0.0909090909090909	1.05771195097038	0.469181814402553	0.816173832536239
GO:0004812	aminoacyl-tRNA ligase activity	4/1602	41/18639	0.0975609756097561	1.13510550835845	0.473665019214843	0.821608333186149
GO:0016875	ligase activity, forming carbon-oxygen bonds	4/1602	41/18639	0.0975609756097561	1.13510550835845	0.473665019214843	0.821608333186149
GO:0001968	fibronectin binding	3/1602	30/18639	0.1	1.16348314606742	0.482801216860498	0.827427681706182
GO:0015215	nucleotide transmembrane transporter activity	3/1602	30/18639	0.1	1.16348314606742	0.482801216860498	0.827427681706182
GO:0016769	transferase activity, transferring nitrogenous groups	3/1602	30/18639	0.1	1.16348314606742	0.482801216860498	0.827427681706182
GO:0031210	phosphatidylcholine binding	3/1602	30/18639	0.1	1.16348314606742	0.482801216860498	0.827427681706182
GO:0033612	receptor serine/threonine kinase binding	3/1602	30/18639	0.1	1.16348314606742	0.482801216860498	0.827427681706182
GO:0035925	mRNA 3'-UTR AU-rich region binding	3/1602	30/18639	0.1	1.16348314606742	0.482801216860498	0.827427681706182
GO:0048019	receptor antagonist activity	3/1602	30/18639	0.1	1.16348314606742	0.482801216860498	0.827427681706182
GO:0140296	general transcription initiation factor binding	5/1602	53/18639	0.0943396226415094	1.09762560949756	0.483179440268457	0.827427681706182
GO:1901505	carbohydrate derivative transmembrane transporter activity	5/1602	53/18639	0.0943396226415094	1.09762560949756	0.483179440268457	0.827427681706182
GO:1902936	phosphatidylinositol bisphosphate binding	10/1602	111/18639	0.0900900900900901	1.04818301447515	0.486729490927108	0.832328082787657
GO:0005525	GTP binding	33/1602	378/18639	0.0873015873015873	1.0157392545033	0.489329964460958	0.834391238362794
GO:0016859	cis-trans isomerase activity	4/1602	42/18639	0.0952380952380952	1.10807918673087	0.492812497834646	0.834391238362794
GO:0003756	protein disulfide isomerase activity	2/1602	19/18639	0.105263157894737	1.2247191011236	0.49483748379332	0.834391238362794
GO:0005229	intracellularly calcium-gated chloride channel activity	2/1602	19/18639	0.105263157894737	1.2247191011236	0.49483748379332	0.834391238362794
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/1602	19/18639	0.105263157894737	1.2247191011236	0.49483748379332	0.834391238362794
GO:0016918	retinal binding	2/1602	19/18639	0.105263157894737	1.2247191011236	0.49483748379332	0.834391238362794
GO:0022821	solute:potassium antiporter activity	2/1602	19/18639	0.105263157894737	1.2247191011236	0.49483748379332	0.834391238362794
GO:0046624	sphingolipid transporter activity	2/1602	19/18639	0.105263157894737	1.2247191011236	0.49483748379332	0.834391238362794
GO:0120227	acyl-CoA binding	2/1602	19/18639	0.105263157894737	1.2247191011236	0.49483748379332	0.834391238362794
GO:0141147	intracellularly calcium-gated channel activity	2/1602	19/18639	0.105263157894737	1.2247191011236	0.49483748379332	0.834391238362794
GO:0015085	calcium ion transmembrane transporter activity	13/1602	147/18639	0.0884353741496599	1.02893067339295	0.499666812955449	0.841360970561473
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	8/1602	89/18639	0.0898876404494382	1.04582754702689	0.501564479239166	0.842210354722434
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	8/1602	89/18639	0.0898876404494382	1.04582754702689	0.501564479239166	0.842210354722434
GO:0005164	tumor necrosis factor receptor binding	3/1602	31/18639	0.0967741935483871	1.12595143167814	0.505125080278462	0.845839642737757
GO:0070273	phosphatidylinositol-4-phosphate binding	3/1602	31/18639	0.0967741935483871	1.12595143167814	0.505125080278462	0.845839642737757
GO:0002020	protease binding	12/1602	136/18639	0.0882352941176471	1.02660277594184	0.506313370649467	0.846656798222968
GO:0005245	voltage-gated calcium channel activity	4/1602	43/18639	0.0930232558139535	1.08230990331853	0.51166099633859	0.854417326758777
GO:0140793	histone H2AXY142 phosphatase activity	8/1602	90/18639	0.0888888888888889	1.03420724094881	0.514530621246775	0.858024167017036
GO:0140313	molecular sequestering activity	5/1602	55/18639	0.0909090909090909	1.05771195097038	0.516618852576921	0.860319824745863
GO:0001614	purinergic nucleotide receptor activity	2/1602	20/18639	0.1	1.16348314606742	0.522696040000634	0.866759103294392
GO:0001972	retinoic acid binding	2/1602	20/18639	0.1	1.16348314606742	0.522696040000634	0.866759103294392
GO:0016502	nucleotide receptor activity	2/1602	20/18639	0.1	1.16348314606742	0.522696040000634	0.866759103294392
GO:0016835	carbon-oxygen lyase activity	7/1602	79/18639	0.0886075949367089	1.03093443322429	0.524238471130109	0.866759103294392
GO:0033293	monocarboxylic acid binding	7/1602	79/18639	0.0886075949367089	1.03093443322429	0.524238471130109	0.866759103294392
GO:0008378	galactosyltransferase activity	3/1602	32/18639	0.09375	1.0907654494382	0.526937916394854	0.866759103294392
GO:0015106	bicarbonate transmembrane transporter activity	3/1602	32/18639	0.09375	1.0907654494382	0.526937916394854	0.866759103294392
GO:0042910	xenobiotic transmembrane transporter activity	3/1602	32/18639	0.09375	1.0907654494382	0.526937916394854	0.866759103294392
GO:0051059	NF-kappaB binding	3/1602	32/18639	0.09375	1.0907654494382	0.526937916394854	0.866759103294392
GO:1901981	phosphatidylinositol phosphate binding	16/1602	185/18639	0.0864864864864865	1.00625569389614	0.527841759557545	0.867066151229717
GO:0030170	pyridoxal phosphate binding	5/1602	56/18639	0.0892857142857143	1.03882423756019	0.532994231192848	0.873157216141129
GO:0170055	lipid transmembrane transporter activity	5/1602	56/18639	0.0892857142857143	1.03882423756019	0.532994231192848	0.873157216141129
GO:0032934	sterol binding	6/1602	68/18639	0.0882352941176471	1.02660277594184	0.535541586580547	0.874959159697137
GO:0140223	general transcription initiation factor activity	6/1602	68/18639	0.0882352941176471	1.02660277594184	0.535541586580547	0.874959159697137
GO:0070851	growth factor receptor binding	12/1602	139/18639	0.0863309352517986	1.00444588149705	0.537618288821503	0.877166681761399
GO:0019239	deaminase activity	3/1602	33/18639	0.0909090909090909	1.05771195097038	0.548205480453833	0.88697800285125
GO:0019956	chemokine binding	3/1602	33/18639	0.0909090909090909	1.05771195097038	0.548205480453833	0.88697800285125
GO:0071889	14-3-3 protein binding	3/1602	33/18639	0.0909090909090909	1.05771195097038	0.548205480453833	0.88697800285125
GO:0140311	protein sequestering activity	3/1602	33/18639	0.0909090909090909	1.05771195097038	0.548205480453833	0.88697800285125
GO:0140416	transcription regulator inhibitor activity	3/1602	33/18639	0.0909090909090909	1.05771195097038	0.548205480453833	0.88697800285125
GO:0009975	cyclase activity	2/1602	21/18639	0.0952380952380952	1.10807918673087	0.549500847093123	0.88697800285125
GO:0051428	peptide hormone receptor binding	2/1602	21/18639	0.0952380952380952	1.10807918673087	0.549500847093123	0.88697800285125
GO:0061891	calcium ion sensor activity	2/1602	21/18639	0.0952380952380952	1.10807918673087	0.549500847093123	0.88697800285125
GO:0051219	phosphoprotein binding	8/1602	93/18639	0.0860215053763441	1.00084571704724	0.552698182620959	0.890289833773852
GO:0019001	guanyl nucleotide binding	34/1602	400/18639	0.085	0.988960674157303	0.553761749377946	0.890289833773852
GO:0032561	guanyl ribonucleotide binding	34/1602	400/18639	0.085	0.988960674157303	0.553761749377946	0.890289833773852
GO:0035591	signaling adaptor activity	11/1602	129/18639	0.0852713178294574	0.992117411375316	0.5567594038837	0.893920477151917
GO:0042562	hormone binding	8/1602	94/18639	0.0851063829787234	0.990198422185035	0.565142946439903	0.895976788833131
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	4/1602	46/18639	0.0869565217391304	1.01172447484123	0.566142862510698	0.895976788833131
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	11/1602	130/18639	0.0846153846153846	0.984485738980121	0.56733727197666	0.895976788833131
GO:0015020	glucuronosyltransferase activity	3/1602	34/18639	0.0882352941176471	1.02660277594184	0.568899492174618	0.895976788833131
GO:0016831	carboxy-lyase activity	3/1602	34/18639	0.0882352941176471	1.02660277594184	0.568899492174618	0.895976788833131
GO:0051427	hormone receptor binding	3/1602	34/18639	0.0882352941176471	1.02660277594184	0.568899492174618	0.895976788833131
GO:0090482	vitamin transmembrane transporter activity	3/1602	34/18639	0.0882352941176471	1.02660277594184	0.568899492174618	0.895976788833131
GO:0008093	cytoskeletal anchor activity	2/1602	22/18639	0.0909090909090909	1.05771195097038	0.575227155904755	0.895976788833131
GO:0016881	acid-amino acid ligase activity	2/1602	22/18639	0.0909090909090909	1.05771195097038	0.575227155904755	0.895976788833131
GO:0140517	protein-RNA adaptor activity	2/1602	22/18639	0.0909090909090909	1.05771195097038	0.575227155904755	0.895976788833131
GO:0140784	metal ion sensor activity	2/1602	22/18639	0.0909090909090909	1.05771195097038	0.575227155904755	0.895976788833131
GO:0004867	serine-type endopeptidase inhibitor activity	8/1602	95/18639	0.0842105263157895	0.979775280898876	0.577433282156705	0.895976788833131
GO:0005262	calcium channel activity	11/1602	131/18639	0.083969465648855	0.976970580667296	0.577811603568304	0.895976788833131
GO:0008135	translation factor activity, RNA binding	7/1602	83/18639	0.0843373493975904	0.981250846080953	0.577864978541767	0.895976788833131
GO:0004879	nuclear receptor activity	5/1602	59/18639	0.0847457627118644	0.986002666158827	0.580516955610531	0.895976788833131
GO:0045309	protein phosphorylated amino acid binding	5/1602	59/18639	0.0847457627118644	0.986002666158827	0.580516955610531	0.895976788833131
GO:0043495	protein-membrane adaptor activity	4/1602	47/18639	0.0851063829787234	0.990198422185035	0.58354115459224	0.895976788833131
GO:0034061	DNA polymerase activity	3/1602	35/18639	0.0857142857142857	0.997271268057785	0.588997181560881	0.895976788833131
GO:0180051	translation factor activity	7/1602	84/18639	0.0833333333333333	0.969569288389513	0.590813243198979	0.895976788833131
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0005381	iron ion transmembrane transporter activity	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0005528	FK506 binding	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0008190	eukaryotic initiation factor 4E binding	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0008401	retinoic acid 4-hydroxylase activity	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0008519	ammonium channel activity	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0015187	glycine transmembrane transporter activity	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0015279	store-operated calcium channel activity	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0015643	toxic substance binding	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0032052	bile acid binding	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0032395	MHC class II receptor activity	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0043121	neurotrophin binding	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0043208	glycosphingolipid binding	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0045322	unmethylated CpG binding	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0050308	sugar-phosphatase activity	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0098505	G-rich strand telomeric DNA binding	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:1905394	retromer complex binding	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/1602	10/18639	0.1	1.16348314606742	0.592988647226919	0.895976788833131
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	5/1602	60/18639	0.0833333333333333	0.969569288389513	0.595771054641863	0.895976788833131
GO:0098531	ligand-modulated transcription factor activity	5/1602	60/18639	0.0833333333333333	0.969569288389513	0.595771054641863	0.895976788833131
GO:0003779	actin binding	37/1602	443/18639	0.0835214446952596	0.971757932381363	0.59836090474867	0.895976788833131
GO:0016493	C-C chemokine receptor activity	2/1602	23/18639	0.0869565217391304	1.01172447484123	0.599862246554228	0.895976788833131
GO:0016849	phosphorus-oxygen lyase activity	2/1602	23/18639	0.0869565217391304	1.01172447484123	0.599862246554228	0.895976788833131
GO:0140103	catalytic activity, acting on a glycoprotein	2/1602	23/18639	0.0869565217391304	1.01172447484123	0.599862246554228	0.895976788833131
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	4/1602	48/18639	0.0833333333333333	0.969569288389513	0.600528335118059	0.895976788833131
GO:0016879	ligase activity, forming carbon-nitrogen bonds	4/1602	48/18639	0.0833333333333333	0.969569288389513	0.600528335118059	0.895976788833131
GO:0004190	aspartic-type endopeptidase activity	3/1602	36/18639	0.0833333333333333	0.969569288389513	0.6084808414458	0.895976788833131
GO:0005484	SNAP receptor activity	3/1602	36/18639	0.0833333333333333	0.969569288389513	0.6084808414458	0.895976788833131
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	3/1602	36/18639	0.0833333333333333	0.969569288389513	0.6084808414458	0.895976788833131
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	3/1602	36/18639	0.0833333333333333	0.969569288389513	0.6084808414458	0.895976788833131
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	3/1602	36/18639	0.0833333333333333	0.969569288389513	0.6084808414458	0.895976788833131
GO:0016836	hydro-lyase activity	5/1602	61/18639	0.0819672131147541	0.953674709891324	0.610709874377859	0.895976788833131
GO:0003684	damaged DNA binding	6/1602	74/18639	0.0810810810810811	0.943364713027634	0.619929770651866	0.895976788833131
GO:0001091	RNA polymerase II general transcription initiation factor binding	2/1602	24/18639	0.0833333333333333	0.969569288389513	0.623403545723328	0.895976788833131
GO:0004622	lysophospholipase activity	2/1602	24/18639	0.0833333333333333	0.969569288389513	0.623403545723328	0.895976788833131
GO:0004806	triacylglycerol lipase activity	2/1602	24/18639	0.0833333333333333	0.969569288389513	0.623403545723328	0.895976788833131
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/1602	24/18639	0.0833333333333333	0.969569288389513	0.623403545723328	0.895976788833131
GO:0019957	C-C chemokine binding	2/1602	24/18639	0.0833333333333333	0.969569288389513	0.623403545723328	0.895976788833131
GO:0030215	semaphorin receptor binding	2/1602	24/18639	0.0833333333333333	0.969569288389513	0.623403545723328	0.895976788833131
GO:0070300	phosphatidic acid binding	2/1602	24/18639	0.0833333333333333	0.969569288389513	0.623403545723328	0.895976788833131
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/1602	24/18639	0.0833333333333333	0.969569288389513	0.623403545723328	0.895976788833131
GO:0042805	actinin binding	3/1602	37/18639	0.0810810810810811	0.943364713027634	0.627337391301128	0.895976788833131
GO:0070001	aspartic-type peptidase activity	3/1602	37/18639	0.0810810810810811	0.943364713027634	0.627337391301128	0.895976788833131
GO:0003953	NAD+ nucleosidase activity	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0005114	type II transforming growth factor beta receptor binding	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0005225	volume-sensitive anion channel activity	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0008046	axon guidance receptor activity	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0008172	S-methyltransferase activity	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0008503	benzodiazepine receptor activity	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0015173	aromatic amino acid transmembrane transporter activity	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0019107	myristoyltransferase activity	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0019203	carbohydrate phosphatase activity	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0019206	nucleoside kinase activity	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0032050	clathrin heavy chain binding	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0032404	mismatch repair complex binding	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0032794	GTPase activating protein binding	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0034713	type I transforming growth factor beta receptor binding	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0042608	T cell receptor binding	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0043522	leucine zipper domain binding	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0045294	alpha-catenin binding	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0047676	arachidonate-CoA ligase activity	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0070697	activin receptor binding	1/1602	11/18639	0.0909090909090909	1.05771195097038	0.627989569828373	0.895976788833131
GO:0044325	transmembrane transporter binding	11/1602	136/18639	0.0808823529411765	0.941052544613351	0.628443603747308	0.895976788833131
GO:0005200	structural constituent of cytoskeleton	9/1602	112/18639	0.0803571428571429	0.934941813804173	0.633034954855363	0.901327098249911
GO:0033218	amide binding	20/1602	247/18639	0.0809716599190283	0.94209161624892	0.643836941100925	0.901327098249911
GO:0019842	vitamin binding	12/1602	150/18639	0.08	0.930786516853933	0.645444901601533	0.901327098249911
GO:0000146	microfilament motor activity	3/1602	38/18639	0.0789473684210526	0.918539325842697	0.64555795581191	0.901327098249911
GO:0042162	telomeric DNA binding	3/1602	38/18639	0.0789473684210526	0.918539325842697	0.64555795581191	0.901327098249911
GO:0008139	nuclear localization sequence binding	2/1602	25/18639	0.08	0.930786516853933	0.645856978389114	0.901327098249911
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/1602	25/18639	0.08	0.930786516853933	0.645856978389114	0.901327098249911
GO:0017025	TBP-class protein binding	2/1602	25/18639	0.08	0.930786516853933	0.645856978389114	0.901327098249911
GO:0017022	myosin binding	6/1602	76/18639	0.0789473684210526	0.918539325842697	0.646037725460597	0.901327098249911
GO:0016829	lyase activity	16/1602	200/18639	0.08	0.930786516853933	0.65538463522036	0.901327098249911
GO:0004126	cytidine deaminase activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0004526	ribonuclease P activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0004859	phospholipase inhibitor activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0005049	nuclear export signal receptor activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0005095	GTPase inhibitor activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0005527	macrolide binding	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0008179	adenylate cyclase binding	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0008603	cAMP-dependent protein kinase regulator activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0010853	cyclase activator activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0015132	prostaglandin transmembrane transporter activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0016208	AMP binding	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0016423	tRNA (guanine) methyltransferase activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0016801	hydrolase activity, acting on ether bonds	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0016803	ether hydrolase activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0035197	siRNA binding	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0043047	single-stranded telomeric DNA binding	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0070008	serine-type exopeptidase activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0070410	co-SMAD binding	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0070679	inositol 1,4,5 trisphosphate binding	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0097677	STAT family protein binding	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0140900	chloride:bicarbonate antiporter activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:1990817	poly(A) RNA polymerase activity	1/1602	12/18639	0.0833333333333333	0.969569288389513	0.659982307059151	0.901327098249911
GO:0004519	endonuclease activity	10/1602	127/18639	0.078740157480315	0.916128461470406	0.660515533826104	0.901327098249911
GO:0000217	DNA secondary structure binding	3/1602	39/18639	0.0769230769230769	0.894987035436474	0.663137460851765	0.901327098249911
GO:0016776	phosphotransferase activity, phosphate group as acceptor	3/1602	39/18639	0.0769230769230769	0.894987035436474	0.663137460851765	0.901327098249911
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	3/1602	39/18639	0.0769230769230769	0.894987035436474	0.663137460851765	0.901327098249911
GO:0001637	G protein-coupled chemoattractant receptor activity	2/1602	26/18639	0.0769230769230769	0.894987035436474	0.667235527653987	0.901327098249911
GO:0004950	chemokine receptor activity	2/1602	26/18639	0.0769230769230769	0.894987035436474	0.667235527653987	0.901327098249911
GO:0005160	transforming growth factor beta receptor binding	2/1602	26/18639	0.0769230769230769	0.894987035436474	0.667235527653987	0.901327098249911
GO:0005227	calcium-activated cation channel activity	2/1602	26/18639	0.0769230769230769	0.894987035436474	0.667235527653987	0.901327098249911
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	2/1602	26/18639	0.0769230769230769	0.894987035436474	0.667235527653987	0.901327098249911
GO:0034237	protein kinase A regulatory subunit binding	2/1602	26/18639	0.0769230769230769	0.894987035436474	0.667235527653987	0.901327098249911
GO:0070412	R-SMAD binding	2/1602	26/18639	0.0769230769230769	0.894987035436474	0.667235527653987	0.901327098249911
GO:0120014	phospholipid transfer activity	2/1602	26/18639	0.0769230769230769	0.894987035436474	0.667235527653987	0.901327098249911
GO:0003774	cytoskeletal motor activity	12/1602	153/18639	0.0784313725490196	0.912535800837189	0.672416634808636	0.907312177995135
GO:0009055	electron transfer activity	9/1602	116/18639	0.0775862068965517	0.902702440914374	0.674578413023588	0.908695016609875
GO:0016251	RNA polymerase II general transcription initiation factor activity	4/1602	53/18639	0.0754716981132075	0.87810048759805	0.678895769709787	0.908695016609875
GO:0016874	ligase activity	13/1602	167/18639	0.0778443113772455	0.905705443046491	0.686336451620665	0.908695016609875
GO:0043178	alcohol binding	7/1602	92/18639	0.0760869565217391	0.885258915486077	0.686509155901767	0.908695016609875
GO:0052689	carboxylic ester hydrolase activity	7/1602	92/18639	0.0760869565217391	0.885258915486077	0.686509155901767	0.908695016609875
GO:0005104	fibroblast growth factor receptor binding	2/1602	27/18639	0.0740740740740741	0.861839367457345	0.687557979112055	0.908695016609875
GO:0015252	proton channel activity	2/1602	27/18639	0.0740740740740741	0.861839367457345	0.687557979112055	0.908695016609875
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/1602	13/18639	0.0769230769230769	0.894987035436474	0.689225252465886	0.908695016609875
GO:0008035	high-density lipoprotein particle binding	1/1602	13/18639	0.0769230769230769	0.894987035436474	0.689225252465886	0.908695016609875
GO:0009982	pseudouridine synthase activity	1/1602	13/18639	0.0769230769230769	0.894987035436474	0.689225252465886	0.908695016609875
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/1602	13/18639	0.0769230769230769	0.894987035436474	0.689225252465886	0.908695016609875
GO:0017154	semaphorin receptor activity	1/1602	13/18639	0.0769230769230769	0.894987035436474	0.689225252465886	0.908695016609875
GO:0019104	DNA N-glycosylase activity	1/1602	13/18639	0.0769230769230769	0.894987035436474	0.689225252465886	0.908695016609875
GO:0019855	calcium channel inhibitor activity	1/1602	13/18639	0.0769230769230769	0.894987035436474	0.689225252465886	0.908695016609875
GO:0031994	insulin-like growth factor I binding	1/1602	13/18639	0.0769230769230769	0.894987035436474	0.689225252465886	0.908695016609875
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/1602	13/18639	0.0769230769230769	0.894987035436474	0.689225252465886	0.908695016609875
GO:0070700	BMP receptor binding	1/1602	13/18639	0.0769230769230769	0.894987035436474	0.689225252465886	0.908695016609875
GO:0071714	icosanoid transmembrane transporter activity	1/1602	13/18639	0.0769230769230769	0.894987035436474	0.689225252465886	0.908695016609875
GO:0071837	HMG box domain binding	1/1602	13/18639	0.0769230769230769	0.894987035436474	0.689225252465886	0.908695016609875
GO:0140333	glycerophospholipid flippase activity	1/1602	13/18639	0.0769230769230769	0.894987035436474	0.689225252465886	0.908695016609875
GO:0140666	annealing activity	1/1602	13/18639	0.0769230769230769	0.894987035436474	0.689225252465886	0.908695016609875
GO:0016853	isomerase activity	14/1602	180/18639	0.0777777777777778	0.904931335830212	0.691365997206866	0.910004051236574
GO:0015485	cholesterol binding	4/1602	54/18639	0.0740740740740741	0.861839367457345	0.693206881318737	0.910004051236574
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	4/1602	54/18639	0.0740740740740741	0.861839367457345	0.693206881318737	0.910004051236574
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	5/1602	67/18639	0.0746268656716418	0.868271004527922	0.693228892629351	0.910004051236574
GO:0042287	MHC protein binding	3/1602	41/18639	0.0731707317073171	0.851329131268841	0.696369714256165	0.912146245434132
GO:0140828	metal cation:monoatomic cation antiporter activity	3/1602	41/18639	0.0731707317073171	0.851329131268841	0.696369714256165	0.912146245434132
GO:0019955	cytokine binding	11/1602	144/18639	0.0763888888888889	0.888771847690387	0.702402673579501	0.917910002190629
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	5/1602	68/18639	0.0735294117647059	0.855502313284864	0.705743758188779	0.917910002190629
GO:0001618	virus receptor activity	6/1602	81/18639	0.0740740740740741	0.861839367457345	0.706345438800113	0.917910002190629
GO:0050698	proteoglycan sulfotransferase activity	2/1602	28/18639	0.0714285714285714	0.831059390048154	0.70684782869943	0.917910002190629
GO:0051959	dynein light intermediate chain binding	2/1602	28/18639	0.0714285714285714	0.831059390048154	0.70684782869943	0.917910002190629
GO:0031492	nucleosomal DNA binding	3/1602	42/18639	0.0714285714285714	0.831059390048154	0.712027961673205	0.917910002190629
GO:0004857	enzyme inhibitor activity	33/1602	416/18639	0.0793269230769231	0.922955380293863	0.712244519990895	0.917910002190629
GO:0004065	arylsulfatase activity	1/1602	14/18639	0.0714285714285714	0.831059390048154	0.71595461709327	0.917910002190629
GO:0005347	ATP transmembrane transporter activity	1/1602	14/18639	0.0714285714285714	0.831059390048154	0.71595461709327	0.917910002190629
GO:0005545	1-phosphatidylinositol binding	1/1602	14/18639	0.0714285714285714	0.831059390048154	0.71595461709327	0.917910002190629
GO:0008191	metalloendopeptidase inhibitor activity	1/1602	14/18639	0.0714285714285714	0.831059390048154	0.71595461709327	0.917910002190629
GO:0008331	high voltage-gated calcium channel activity	1/1602	14/18639	0.0714285714285714	0.831059390048154	0.71595461709327	0.917910002190629
GO:0015386	potassium:proton antiporter activity	1/1602	14/18639	0.0714285714285714	0.831059390048154	0.71595461709327	0.917910002190629
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/1602	14/18639	0.0714285714285714	0.831059390048154	0.71595461709327	0.917910002190629
GO:0019992	diacylglycerol binding	1/1602	14/18639	0.0714285714285714	0.831059390048154	0.71595461709327	0.917910002190629
GO:0034236	protein kinase A catalytic subunit binding	1/1602	14/18639	0.0714285714285714	0.831059390048154	0.71595461709327	0.917910002190629
GO:0043176	amine binding	1/1602	14/18639	0.0714285714285714	0.831059390048154	0.71595461709327	0.917910002190629
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/1602	14/18639	0.0714285714285714	0.831059390048154	0.71595461709327	0.917910002190629
GO:0070742	C2H2 zinc finger domain binding	1/1602	14/18639	0.0714285714285714	0.831059390048154	0.71595461709327	0.917910002190629
GO:1901474	azole transmembrane transporter activity	1/1602	14/18639	0.0714285714285714	0.831059390048154	0.71595461709327	0.917910002190629
GO:0140272	exogenous protein binding	6/1602	82/18639	0.0731707317073171	0.851329131268841	0.717526148948211	0.918950332710155
GO:0003785	actin monomer binding	2/1602	29/18639	0.0689655172413793	0.802402169701666	0.725132335228351	0.922826308727449
GO:0004181	metallocarboxypeptidase activity	2/1602	29/18639	0.0689655172413793	0.802402169701666	0.725132335228351	0.922826308727449
GO:0043236	laminin binding	2/1602	29/18639	0.0689655172413793	0.802402169701666	0.725132335228351	0.922826308727449
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	2/1602	29/18639	0.0689655172413793	0.802402169701666	0.725132335228351	0.922826308727449
GO:0051861	glycolipid binding	2/1602	29/18639	0.0689655172413793	0.802402169701666	0.725132335228351	0.922826308727449
GO:0106222	lncRNA binding	2/1602	29/18639	0.0689655172413793	0.802402169701666	0.725132335228351	0.922826308727449
GO:0008375	acetylglucosaminyltransferase activity	3/1602	43/18639	0.0697674418604651	0.811732427488895	0.727055484073301	0.923329916223341
GO:0048156	tau protein binding	3/1602	43/18639	0.0697674418604651	0.811732427488895	0.727055484073301	0.923329916223341
GO:0004896	cytokine receptor activity	7/1602	96/18639	0.0729166666666667	0.848373127340824	0.728567424693204	0.924279135838493
GO:0015078	proton transmembrane transporter activity	14/1602	185/18639	0.0756756756756757	0.880473732159125	0.729372837970204	0.924330986484252
GO:0004467	long-chain fatty acid-CoA ligase activity	1/1602	15/18639	0.0666666666666667	0.77565543071161	0.740386332712952	0.924420202161381
GO:0005523	tropomyosin binding	1/1602	15/18639	0.0666666666666667	0.77565543071161	0.740386332712952	0.924420202161381
GO:0015929	hexosaminidase activity	1/1602	15/18639	0.0666666666666667	0.77565543071161	0.740386332712952	0.924420202161381
GO:0017081	chloride channel regulator activity	1/1602	15/18639	0.0666666666666667	0.77565543071161	0.740386332712952	0.924420202161381
GO:0030553	cGMP binding	1/1602	15/18639	0.0666666666666667	0.77565543071161	0.740386332712952	0.924420202161381
GO:0031386	protein tag activity	1/1602	15/18639	0.0666666666666667	0.77565543071161	0.740386332712952	0.924420202161381
GO:0045504	dynein heavy chain binding	1/1602	15/18639	0.0666666666666667	0.77565543071161	0.740386332712952	0.924420202161381
GO:0047372	monoacylglycerol lipase activity	1/1602	15/18639	0.0666666666666667	0.77565543071161	0.740386332712952	0.924420202161381
GO:0051371	muscle alpha-actinin binding	1/1602	15/18639	0.0666666666666667	0.77565543071161	0.740386332712952	0.924420202161381
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/1602	15/18639	0.0666666666666667	0.77565543071161	0.740386332712952	0.924420202161381
GO:0141047	molecular tag activity	1/1602	15/18639	0.0666666666666667	0.77565543071161	0.740386332712952	0.924420202161381
GO:0140299	molecular sensor activity	5/1602	71/18639	0.0704225352112676	0.81935432821649	0.741120328641732	0.924420202161381
GO:0019205	nucleobase-containing compound kinase activity	3/1602	44/18639	0.0681818181818182	0.793283963227783	0.741460864097435	0.924420202161381
GO:0030547	signaling receptor inhibitor activity	3/1602	44/18639	0.0681818181818182	0.793283963227783	0.741460864097435	0.924420202161381
GO:0001965	G-protein alpha-subunit binding	2/1602	30/18639	0.0666666666666667	0.77565543071161	0.742441700826055	0.924420202161381
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/1602	30/18639	0.0666666666666667	0.77565543071161	0.742441700826055	0.924420202161381
GO:0022839	monoatomic ion-gated channel activity	2/1602	30/18639	0.0666666666666667	0.77565543071161	0.742441700826055	0.924420202161381
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/1602	31/18639	0.0645161290322581	0.75063428778543	0.758808364312096	0.938073052236321
GO:0008327	methyl-CpG binding	2/1602	31/18639	0.0645161290322581	0.75063428778543	0.758808364312096	0.938073052236321
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	6/1602	86/18639	0.0697674418604651	0.811732427488895	0.759268182389327	0.938073052236321
GO:0015385	sodium:proton antiporter activity	1/1602	16/18639	0.0625	0.727176966292135	0.762717791851367	0.938073052236321
GO:0017070	U6 snRNA binding	1/1602	16/18639	0.0625	0.727176966292135	0.762717791851367	0.938073052236321
GO:0019841	retinol binding	1/1602	16/18639	0.0625	0.727176966292135	0.762717791851367	0.938073052236321
GO:0022841	potassium ion leak channel activity	1/1602	16/18639	0.0625	0.727176966292135	0.762717791851367	0.938073052236321
GO:0043023	ribosomal large subunit binding	1/1602	16/18639	0.0625	0.727176966292135	0.762717791851367	0.938073052236321
GO:0055102	lipase inhibitor activity	1/1602	16/18639	0.0625	0.727176966292135	0.762717791851367	0.938073052236321
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/1602	16/18639	0.0625	0.727176966292135	0.762717791851367	0.938073052236321
GO:0097027	ubiquitin-protein transferase activator activity	1/1602	16/18639	0.0625	0.727176966292135	0.762717791851367	0.938073052236321
GO:0140327	flippase activity	1/1602	16/18639	0.0625	0.727176966292135	0.762717791851367	0.938073052236321
GO:0030291	protein serine/threonine kinase inhibitor activity	3/1602	46/18639	0.0652173913043478	0.758793356130923	0.768448331348792	0.944150217453041
GO:0071813	lipoprotein particle binding	2/1602	32/18639	0.0625	0.727176966292135	0.774266394173245	0.944150217453041
GO:0071814	protein-lipid complex binding	2/1602	32/18639	0.0625	0.727176966292135	0.774266394173245	0.944150217453041
GO:0005506	iron ion binding	11/1602	154/18639	0.0714285714285714	0.831059390048154	0.78091509164426	0.944150217453041
GO:0001784	phosphotyrosine residue binding	3/1602	47/18639	0.0638297872340425	0.742648816638776	0.781055638854921	0.944150217453041
GO:0005504	fatty acid binding	3/1602	47/18639	0.0638297872340425	0.742648816638776	0.781055638854921	0.944150217453041
GO:0099095	ligand-gated monoatomic anion channel activity	3/1602	47/18639	0.0638297872340425	0.742648816638776	0.781055638854921	0.944150217453041
GO:0004549	tRNA-specific ribonuclease activity	1/1602	17/18639	0.0588235294117647	0.684401850627892	0.783129438602917	0.944150217453041
GO:0005092	GDP-dissociation inhibitor activity	1/1602	17/18639	0.0588235294117647	0.684401850627892	0.783129438602917	0.944150217453041
GO:0008429	phosphatidylethanolamine binding	1/1602	17/18639	0.0588235294117647	0.684401850627892	0.783129438602917	0.944150217453041
GO:0009881	photoreceptor activity	1/1602	17/18639	0.0588235294117647	0.684401850627892	0.783129438602917	0.944150217453041
GO:0016018	cyclosporin A binding	1/1602	17/18639	0.0588235294117647	0.684401850627892	0.783129438602917	0.944150217453041
GO:0030548	acetylcholine receptor regulator activity	1/1602	17/18639	0.0588235294117647	0.684401850627892	0.783129438602917	0.944150217453041
GO:0031489	myosin V binding	1/1602	17/18639	0.0588235294117647	0.684401850627892	0.783129438602917	0.944150217453041
GO:0045125	bioactive lipid receptor activity	1/1602	17/18639	0.0588235294117647	0.684401850627892	0.783129438602917	0.944150217453041
GO:0045236	CXCR chemokine receptor binding	1/1602	17/18639	0.0588235294117647	0.684401850627892	0.783129438602917	0.944150217453041
GO:0048038	quinone binding	1/1602	17/18639	0.0588235294117647	0.684401850627892	0.783129438602917	0.944150217453041
GO:0070402	NADPH binding	1/1602	17/18639	0.0588235294117647	0.684401850627892	0.783129438602917	0.944150217453041
GO:1990226	histone methyltransferase binding	1/1602	17/18639	0.0588235294117647	0.684401850627892	0.783129438602917	0.944150217453041
GO:0019003	GDP binding	5/1602	75/18639	0.0666666666666667	0.77565543071161	0.783277641112821	0.944150217453041
GO:0022804	active transmembrane transporter activity	35/1602	457/18639	0.0765864332603939	0.891070243158852	0.788111210695392	0.949030332401125
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	13/1602	181/18639	0.0718232044198895	0.835650878390962	0.788934993651808	0.949077022213966
GO:0003746	translation elongation factor activity	1/1602	18/18639	0.0555555555555556	0.646379525593009	0.80178622301695	0.955034033130535
GO:0004970	glutamate-gated receptor activity	1/1602	18/18639	0.0555555555555556	0.646379525593009	0.80178622301695	0.955034033130535
GO:0008409	5'-3' exonuclease activity	1/1602	18/18639	0.0555555555555556	0.646379525593009	0.80178622301695	0.955034033130535
GO:0008525	phosphatidylcholine transporter activity	1/1602	18/18639	0.0555555555555556	0.646379525593009	0.80178622301695	0.955034033130535
GO:0015280	ligand-gated sodium channel activity	1/1602	18/18639	0.0555555555555556	0.646379525593009	0.80178622301695	0.955034033130535
GO:0022851	GABA-gated chloride ion channel activity	1/1602	18/18639	0.0555555555555556	0.646379525593009	0.80178622301695	0.955034033130535
GO:0050811	GABA receptor binding	1/1602	18/18639	0.0555555555555556	0.646379525593009	0.80178622301695	0.955034033130535
GO:0070628	proteasome binding	1/1602	18/18639	0.0555555555555556	0.646379525593009	0.80178622301695	0.955034033130535
GO:0099602	neurotransmitter receptor regulator activity	1/1602	18/18639	0.0555555555555556	0.646379525593009	0.80178622301695	0.955034033130535
GO:1990381	ubiquitin-specific protease binding	1/1602	18/18639	0.0555555555555556	0.646379525593009	0.80178622301695	0.955034033130535
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/1602	34/18639	0.0588235294117647	0.684401850627892	0.802597936569248	0.955059946173446
GO:0060590	ATPase regulator activity	3/1602	49/18639	0.0612244897959184	0.712336620041275	0.804569071810883	0.956341025264265
GO:0022853	active monoatomic ion transmembrane transporter activity	8/1602	118/18639	0.0677966101694915	0.788802132927061	0.805256545673302	0.956341025264265
GO:0005126	cytokine receptor binding	20/1602	275/18639	0.0727272727272727	0.846169560776302	0.813632514309747	0.957423856168936
GO:0032813	tumor necrosis factor receptor superfamily binding	3/1602	50/18639	0.06	0.698089887640449	0.815506483593613	0.957423856168936
GO:0005154	epidermal growth factor receptor binding	2/1602	35/18639	0.0571428571428571	0.664847512038523	0.815543436872786	0.957423856168936
GO:0061631	ubiquitin conjugating enzyme activity	2/1602	35/18639	0.0571428571428571	0.664847512038523	0.815543436872786	0.957423856168936
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/1602	19/18639	0.0526315789473684	0.612359550561798	0.818838930751596	0.957423856168936
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/1602	19/18639	0.0526315789473684	0.612359550561798	0.818838930751596	0.957423856168936
GO:0004890	GABA-A receptor activity	1/1602	19/18639	0.0526315789473684	0.612359550561798	0.818838930751596	0.957423856168936
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/1602	19/18639	0.0526315789473684	0.612359550561798	0.818838930751596	0.957423856168936
GO:0005520	insulin-like growth factor binding	1/1602	19/18639	0.0526315789473684	0.612359550561798	0.818838930751596	0.957423856168936
GO:0008301	DNA binding, bending	1/1602	19/18639	0.0526315789473684	0.612359550561798	0.818838930751596	0.957423856168936
GO:0008381	mechanosensitive monoatomic ion channel activity	1/1602	19/18639	0.0526315789473684	0.612359550561798	0.818838930751596	0.957423856168936
GO:0008574	plus-end-directed microtubule motor activity	1/1602	19/18639	0.0526315789473684	0.612359550561798	0.818838930751596	0.957423856168936
GO:0022840	leak channel activity	1/1602	19/18639	0.0526315789473684	0.612359550561798	0.818838930751596	0.957423856168936
GO:0022842	narrow pore channel activity	1/1602	19/18639	0.0526315789473684	0.612359550561798	0.818838930751596	0.957423856168936
GO:0042834	peptidoglycan binding	1/1602	19/18639	0.0526315789473684	0.612359550561798	0.818838930751596	0.957423856168936
GO:0097001	ceramide binding	1/1602	19/18639	0.0526315789473684	0.612359550561798	0.818838930751596	0.957423856168936
GO:0019843	rRNA binding	4/1602	65/18639	0.0615384615384615	0.715989628349179	0.820924477630652	0.958934969522182
GO:0051087	protein-folding chaperone binding	9/1602	134/18639	0.0671641791044776	0.78144390407513	0.82367175832527	0.961215401366073
GO:0031406	carboxylic acid binding	13/1602	187/18639	0.0695187165775401	0.808838550742054	0.824752823238107	0.961548855636328
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/1602	36/18639	0.0555555555555556	0.646379525593009	0.827723589544962	0.962228672846018
GO:0045505	dynein intermediate chain binding	2/1602	36/18639	0.0555555555555556	0.646379525593009	0.827723589544962	0.962228672846018
GO:0055106	ubiquitin-protein transferase regulator activity	2/1602	36/18639	0.0555555555555556	0.646379525593009	0.827723589544962	0.962228672846018
GO:0005496	steroid binding	7/1602	108/18639	0.0648148148148148	0.754109446525177	0.83059953182477	0.964455360431359
GO:0010851	cyclase regulator activity	1/1602	20/18639	0.05	0.581741573033708	0.834425398685858	0.964455360431359
GO:0016408	C-acyltransferase activity	1/1602	20/18639	0.05	0.581741573033708	0.834425398685858	0.964455360431359
GO:0030627	pre-mRNA 5'-splice site binding	1/1602	20/18639	0.05	0.581741573033708	0.834425398685858	0.964455360431359
GO:0042288	MHC class I protein binding	1/1602	20/18639	0.05	0.581741573033708	0.834425398685858	0.964455360431359
GO:0140664	ATP-dependent DNA damage sensor activity	1/1602	20/18639	0.05	0.581741573033708	0.834425398685858	0.964455360431359
GO:0043177	organic acid binding	13/1602	189/18639	0.0687830687830688	0.800279412638963	0.835625677883139	0.964744289861739
GO:0030971	receptor tyrosine kinase binding	5/1602	81/18639	0.0617283950617284	0.718199472881121	0.836271311641938	0.964744289861739
GO:0016860	intramolecular oxidoreductase activity	3/1602	53/18639	0.0566037735849057	0.658575365698537	0.845241185822322	0.971632572116461
GO:0003777	microtubule motor activity	4/1602	68/18639	0.0588235294117647	0.684401850627892	0.846985332660685	0.971632572116461
GO:0001846	opsonin binding	1/1602	21/18639	0.0476190476190476	0.554039593365436	0.848671626265494	0.971632572116461
GO:0005123	death receptor binding	1/1602	21/18639	0.0476190476190476	0.554039593365436	0.848671626265494	0.971632572116461
GO:0015125	bile acid transmembrane transporter activity	1/1602	21/18639	0.0476190476190476	0.554039593365436	0.848671626265494	0.971632572116461
GO:0036122	BMP binding	1/1602	21/18639	0.0476190476190476	0.554039593365436	0.848671626265494	0.971632572116461
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/1602	21/18639	0.0476190476190476	0.554039593365436	0.848671626265494	0.971632572116461
GO:0070182	DNA polymerase binding	1/1602	21/18639	0.0476190476190476	0.554039593365436	0.848671626265494	0.971632572116461
GO:0043531	ADP binding	2/1602	38/18639	0.0526315789473684	0.612359550561798	0.84993068909087	0.972153456112452
GO:0003925	G protein activity	3/1602	54/18639	0.0555555555555556	0.646379525593009	0.854184380204886	0.976095383428835
GO:0008236	serine-type peptidase activity	13/1602	194/18639	0.0670103092783505	0.779653654581258	0.860560214527945	0.980043824034438
GO:0005243	gap junction channel activity	1/1602	22/18639	0.0454545454545455	0.528855975485189	0.861692791520768	0.980043824034438
GO:0008649	rRNA methyltransferase activity	1/1602	22/18639	0.0454545454545455	0.528855975485189	0.861692791520768	0.980043824034438
GO:0008970	phospholipase A1 activity	1/1602	22/18639	0.0454545454545455	0.528855975485189	0.861692791520768	0.980043824034438
GO:0031683	G-protein beta/gamma-subunit complex binding	1/1602	22/18639	0.0454545454545455	0.528855975485189	0.861692791520768	0.980043824034438
GO:0008028	monocarboxylic acid transmembrane transporter activity	4/1602	70/18639	0.0571428571428571	0.664847512038523	0.86251950675981	0.980062108714859
GO:0051015	actin filament binding	14/1602	209/18639	0.0669856459330144	0.779366700715015	0.868250020795097	0.984907790715113
GO:0030414	peptidase inhibitor activity	11/1602	169/18639	0.0650887573964497	0.757296722292401	0.869071475874861	0.984907790715113
GO:0140662	ATP-dependent protein folding chaperone	2/1602	40/18639	0.05	0.581741573033708	0.869498850430285	0.984907790715113
GO:0000295	adenine nucleotide transmembrane transporter activity	1/1602	23/18639	0.0434782608695652	0.505862237420616	0.873594179928338	0.984907790715113
GO:0004602	glutathione peroxidase activity	1/1602	23/18639	0.0434782608695652	0.505862237420616	0.873594179928338	0.984907790715113
GO:0016917	GABA receptor activity	1/1602	23/18639	0.0434782608695652	0.505862237420616	0.873594179928338	0.984907790715113
GO:0140102	catalytic activity, acting on a rRNA	1/1602	23/18639	0.0434782608695652	0.505862237420616	0.873594179928338	0.984907790715113
GO:0017171	serine hydrolase activity	13/1602	198/18639	0.0656565656565657	0.763903075700829	0.878292847440847	0.984907790715113
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	2/1602	41/18639	0.0487804878048781	0.567552754179227	0.878377267669984	0.984907790715113
GO:0016877	ligase activity, forming carbon-sulfur bonds	2/1602	41/18639	0.0487804878048781	0.567552754179227	0.878377267669984	0.984907790715113
GO:0017080	sodium channel regulator activity	2/1602	41/18639	0.0487804878048781	0.567552754179227	0.878377267669984	0.984907790715113
GO:0061650	ubiquitin-like protein conjugating enzyme activity	2/1602	41/18639	0.0487804878048781	0.567552754179227	0.878377267669984	0.984907790715113
GO:0016651	oxidoreductase activity, acting on NAD(P)H	5/1602	88/18639	0.0568181818181818	0.661069969356486	0.884164987096132	0.984907790715113
GO:0005315	phosphate transmembrane transporter activity	1/1602	24/18639	0.0416666666666667	0.484784644194757	0.884472033589425	0.984907790715113
GO:0005540	hyaluronic acid binding	1/1602	24/18639	0.0416666666666667	0.484784644194757	0.884472033589425	0.984907790715113
GO:0015149	hexose transmembrane transporter activity	1/1602	24/18639	0.0416666666666667	0.484784644194757	0.884472033589425	0.984907790715113
GO:0015295	solute:proton symporter activity	1/1602	24/18639	0.0416666666666667	0.484784644194757	0.884472033589425	0.984907790715113
GO:0055056	D-glucose transmembrane transporter activity	1/1602	24/18639	0.0416666666666667	0.484784644194757	0.884472033589425	0.984907790715113
GO:0140612	DNA damage sensor activity	1/1602	24/18639	0.0416666666666667	0.484784644194757	0.884472033589425	0.984907790715113
GO:0008307	structural constituent of muscle	2/1602	42/18639	0.0476190476190476	0.554039593365436	0.886694732969823	0.984907790715113
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	8/1602	132/18639	0.0606060606060606	0.705141300646919	0.889439681881472	0.984907790715113
GO:0001786	phosphatidylserine binding	3/1602	59/18639	0.0508474576271186	0.591601599695296	0.892421964265824	0.984907790715113
GO:0015459	potassium channel regulator activity	3/1602	59/18639	0.0508474576271186	0.591601599695296	0.892421964265824	0.984907790715113
GO:0004866	endopeptidase inhibitor activity	10/1602	161/18639	0.062111801242236	0.722660339172308	0.894380477913322	0.984907790715113
GO:0001848	complement binding	1/1602	25/18639	0.04	0.465393258426966	0.894414327556105	0.984907790715113
GO:0003707	nuclear steroid receptor activity	1/1602	25/18639	0.04	0.465393258426966	0.894414327556105	0.984907790715113
GO:0005251	delayed rectifier potassium channel activity	1/1602	25/18639	0.04	0.465393258426966	0.894414327556105	0.984907790715113
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/1602	25/18639	0.04	0.465393258426966	0.894414327556105	0.984907790715113
GO:0015645	fatty acid ligase activity	1/1602	25/18639	0.04	0.465393258426966	0.894414327556105	0.984907790715113
GO:0015662	P-type ion transporter activity	1/1602	25/18639	0.04	0.465393258426966	0.894414327556105	0.984907790715113
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/1602	25/18639	0.04	0.465393258426966	0.894414327556105	0.984907790715113
GO:0120515	fatty acid-CoA ligase activity	1/1602	25/18639	0.04	0.465393258426966	0.894414327556105	0.984907790715113
GO:0140358	P-type transmembrane transporter activity	1/1602	25/18639	0.04	0.465393258426966	0.894414327556105	0.984907790715113
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/1602	43/18639	0.0465116279069767	0.541154951659263	0.8944820134038	0.984907790715113
GO:0044183	protein folding chaperone	4/1602	75/18639	0.0533333333333333	0.620524344569288	0.895553628445926	0.985190479336783
GO:0004529	DNA exonuclease activity	1/1602	26/18639	0.0384615384615385	0.447493517718237	0.903501479552189	0.988536912921807
GO:0008066	glutamate receptor activity	1/1602	26/18639	0.0384615384615385	0.447493517718237	0.903501479552189	0.988536912921807
GO:0015145	monosaccharide transmembrane transporter activity	1/1602	26/18639	0.0384615384615385	0.447493517718237	0.903501479552189	0.988536912921807
GO:0019865	immunoglobulin binding	1/1602	26/18639	0.0384615384615385	0.447493517718237	0.903501479552189	0.988536912921807
GO:0051139	metal cation:proton antiporter activity	1/1602	26/18639	0.0384615384615385	0.447493517718237	0.903501479552189	0.988536912921807
GO:0097602	cullin family protein binding	1/1602	26/18639	0.0384615384615385	0.447493517718237	0.903501479552189	0.988536912921807
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	7/1602	122/18639	0.0573770491803279	0.667572296923927	0.908481964687537	0.992541671712336
GO:0015291	secondary active transmembrane transporter activity	19/1602	287/18639	0.0662020905923345	0.770250166386094	0.908803664669608	0.992541671712336
GO:0001671	ATPase activator activity	1/1602	27/18639	0.037037037037037	0.430919683728672	0.911806998799887	0.993130325719877
GO:0008395	steroid hydroxylase activity	1/1602	27/18639	0.037037037037037	0.430919683728672	0.911806998799887	0.993130325719877
GO:0016405	CoA-ligase activity	1/1602	27/18639	0.037037037037037	0.430919683728672	0.911806998799887	0.993130325719877
GO:0003730	mRNA 3'-UTR binding	17/1602	262/18639	0.0648854961832061	0.754931812333819	0.91379217928436	0.994396709950307
GO:0005507	copper ion binding	3/1602	63/18639	0.0476190476190476	0.554039593365436	0.916254752538277	0.996014585771809
GO:0016866	intramolecular transferase activity	1/1602	28/18639	0.0357142857142857	0.415529695024077	0.919398079173978	0.996014585771809
GO:0046625	sphingolipid binding	1/1602	28/18639	0.0357142857142857	0.415529695024077	0.919398079173978	0.996014585771809
GO:0051119	sugar transmembrane transporter activity	1/1602	28/18639	0.0357142857142857	0.415529695024077	0.919398079173978	0.996014585771809
GO:0051537	2 iron, 2 sulfur cluster binding	1/1602	28/18639	0.0357142857142857	0.415529695024077	0.919398079173978	0.996014585771809
GO:0030246	carbohydrate binding	18/1602	280/18639	0.0642857142857143	0.747953451043339	0.925751990110893	0.999999999933477
GO:0035254	glutamate receptor binding	2/1602	49/18639	0.0408163265306122	0.474891080027517	0.931648124961486	0.999999999933477
GO:0005254	chloride channel activity	4/1602	83/18639	0.0481927710843374	0.560714769189116	0.933995701684198	0.999999999933477
GO:0005184	neuropeptide hormone activity	1/1602	31/18639	0.032258064516129	0.375317143892715	0.938472961224194	0.999999999933477
GO:0005452	solute:inorganic anion antiporter activity	1/1602	31/18639	0.032258064516129	0.375317143892715	0.938472961224194	0.999999999933477
GO:0016878	acid-thiol ligase activity	1/1602	31/18639	0.032258064516129	0.375317143892715	0.938472961224194	0.999999999933477
GO:0047499	calcium-independent phospholipase A2 activity	1/1602	31/18639	0.032258064516129	0.375317143892715	0.938472961224194	0.999999999933477
GO:0099106	ion channel regulator activity	9/1602	160/18639	0.05625	0.654459269662921	0.939181513091659	0.999999999933477
GO:0016597	amino acid binding	2/1602	51/18639	0.0392156862745098	0.456267900418594	0.941000329855991	0.999999999933477
GO:0004252	serine-type endopeptidase activity	10/1602	176/18639	0.0568181818181818	0.661069969356486	0.943148107783441	0.999999999933477
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/1602	32/18639	0.03125	0.363588483146067	0.943769947258096	0.999999999933477
GO:0047498	calcium-dependent phospholipase A2 activity	1/1602	32/18639	0.03125	0.363588483146067	0.943769947258096	0.999999999933477
GO:0160041	neuropeptide activity	1/1602	32/18639	0.03125	0.363588483146067	0.943769947258096	0.999999999933477
GO:0008083	growth factor activity	9/1602	162/18639	0.0555555555555556	0.646379525593009	0.944384953747233	0.999999999933477
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/1602	33/18639	0.0303030303030303	0.352570650323459	0.948611165320789	0.999999999933477
GO:0030296	protein tyrosine kinase activator activity	1/1602	33/18639	0.0303030303030303	0.352570650323459	0.948611165320789	0.999999999933477
GO:0004864	protein phosphatase inhibitor activity	2/1602	53/18639	0.0377358490566038	0.439050243799025	0.949127567568779	0.999999999933477
GO:0005544	calcium-dependent phospholipid binding	2/1602	53/18639	0.0377358490566038	0.439050243799025	0.949127567568779	0.999999999933477
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/1602	53/18639	0.0377358490566038	0.439050243799025	0.949127567568779	0.999999999933477
GO:0015103	inorganic anion transmembrane transporter activity	9/1602	165/18639	0.0545454545454545	0.634627170582227	0.95145642559253	0.999999999933477
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	1/1602	34/18639	0.0294117647058824	0.342200925313946	0.95303580861629	0.999999999933477
GO:0019825	oxygen binding	1/1602	34/18639	0.0294117647058824	0.342200925313946	0.95303580861629	0.999999999933477
GO:0004521	RNA endonuclease activity	3/1602	73/18639	0.0410958904109589	0.478143758657842	0.956270628177244	0.999999999933477
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	3/1602	73/18639	0.0410958904109589	0.478143758657842	0.956270628177244	0.999999999933477
GO:0008528	G protein-coupled peptide receptor activity	6/1602	122/18639	0.0491803278688525	0.572204825934795	0.956621198062781	0.999999999933477
GO:0004623	phospholipase A2 activity	1/1602	35/18639	0.0285714285714286	0.332423756019262	0.957079701902864	0.999999999933477
GO:0016229	steroid dehydrogenase activity	1/1602	35/18639	0.0285714285714286	0.332423756019262	0.957079701902864	0.999999999933477
GO:0061134	peptidase regulator activity	13/1602	226/18639	0.0575221238938053	0.669260216764443	0.957547117990915	0.999999999933477
GO:0016247	channel regulator activity	9/1602	168/18639	0.0535714285714286	0.623294542536116	0.95771951701811	0.999999999933477
GO:0019212	phosphatase inhibitor activity	2/1602	56/18639	0.0357142857142857	0.415529695024077	0.959344535884504	0.999999999933477
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	2/1602	56/18639	0.0357142857142857	0.415529695024077	0.959344535884504	0.999999999933477
GO:0061135	endopeptidase regulator activity	10/1602	184/18639	0.0543478260869565	0.632327796775769	0.96003445715909	0.999999999933477
GO:0004033	aldo-keto reductase (NADPH) activity	1/1602	36/18639	0.0277777777777778	0.323189762796504	0.960775590827375	0.999999999933477
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/1602	36/18639	0.0277777777777778	0.323189762796504	0.960775590827375	0.999999999933477
GO:0141108	transporter regulator activity	9/1602	170/18639	0.0529411764705882	0.615961665565102	0.961484044777531	0.999999999933477
GO:0004601	peroxidase activity	2/1602	57/18639	0.0350877192982456	0.408239700374532	0.962289669276139	0.999999999933477
GO:0016504	peptidase activator activity	2/1602	57/18639	0.0350877192982456	0.408239700374532	0.962289669276139	0.999999999933477
GO:0140375	immune receptor activity	8/1602	156/18639	0.0512820512820513	0.596658023624316	0.963345728238163	0.999999999933477
GO:0022829	wide pore channel activity	1/1602	37/18639	0.027027027027027	0.314454904342545	0.964153406421341	0.999999999933477
GO:0030551	cyclic nucleotide binding	1/1602	37/18639	0.027027027027027	0.314454904342545	0.964153406421341	0.999999999933477
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	2/1602	58/18639	0.0344827586206897	0.401201084850833	0.965029275720964	0.999999999933477
GO:0020037	heme binding	7/1602	142/18639	0.0492957746478873	0.573548029751543	0.965698701961889	0.999999999933477
GO:0005244	voltage-gated monoatomic ion channel activity	9/1602	173/18639	0.0520231213872832	0.605280249399234	0.966568717990938	0.999999999933477
GO:0022843	voltage-gated monoatomic cation channel activity	7/1602	143/18639	0.048951048951049	0.569537204368665	0.967430219057185	0.999999999933477
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	2/1602	59/18639	0.0338983050847458	0.394401066463531	0.967576900684303	0.999999999933477
GO:0001653	peptide receptor activity	6/1602	128/18639	0.046875	0.545382724719101	0.968635679952118	0.999999999933477
GO:0022832	voltage-gated channel activity	9/1602	175/18639	0.0514285714285714	0.598362760834671	0.969613606430093	0.999999999933477
GO:0015144	carbohydrate transmembrane transporter activity	1/1602	40/18639	0.025	0.290870786516854	0.972640438338563	0.999999999933477
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	1/1602	40/18639	0.025	0.290870786516854	0.972640438338563	0.999999999933477
GO:0071855	neuropeptide receptor binding	1/1602	40/18639	0.025	0.290870786516854	0.972640438338563	0.999999999933477
GO:0001530	lipopolysaccharide binding	1/1602	41/18639	0.024390243902439	0.283776377089614	0.974997017605277	0.999999999933477
GO:0008137	NADH dehydrogenase (ubiquinone) activity	1/1602	41/18639	0.024390243902439	0.283776377089614	0.974997017605277	0.999999999933477
GO:0022824	transmitter-gated monoatomic ion channel activity	2/1602	63/18639	0.0317460317460317	0.369359728910291	0.976091011570612	0.999999999933477
GO:0022835	transmitter-gated channel activity	2/1602	63/18639	0.0317460317460317	0.369359728910291	0.976091011570612	0.999999999933477
GO:0008200	ion channel inhibitor activity	1/1602	43/18639	0.0232558139534884	0.270577475829632	0.979119034685176	0.999999999933477
GO:0046906	tetrapyrrole binding	7/1602	152/18639	0.0460526315789474	0.535814606741573	0.979778102127027	0.999999999933477
GO:0099094	ligand-gated monoatomic cation channel activity	6/1602	136/18639	0.0441176470588235	0.513301387970919	0.979922427531904	0.999999999933477
GO:0005253	monoatomic anion channel activity	4/1602	103/18639	0.0388349514563107	0.451838114977637	0.980741303827997	0.999999999933477
GO:0003954	NADH dehydrogenase activity	1/1602	44/18639	0.0227272727272727	0.264427987742595	0.980917878868567	0.999999999933477
GO:0016248	channel inhibitor activity	1/1602	44/18639	0.0227272727272727	0.264427987742595	0.980917878868567	0.999999999933477
GO:0015108	chloride transmembrane transporter activity	5/1602	121/18639	0.0413223140495868	0.48077815953199	0.981706059060631	0.999999999933477
GO:0051082	unfolded protein binding	5/1602	121/18639	0.0413223140495868	0.48077815953199	0.981706059060631	0.999999999933477
GO:0141110	transporter inhibitor activity	1/1602	45/18639	0.0222222222222222	0.258551810237203	0.982561845421541	0.999999999933477
GO:0005125	cytokine activity	12/1602	234/18639	0.0512820512820513	0.596658023624316	0.984084904190364	0.999999999933477
GO:0098960	postsynaptic neurotransmitter receptor activity	2/1602	69/18639	0.0289855072463768	0.337241491613744	0.984944674758898	0.999999999933477
GO:0008188	neuropeptide receptor activity	1/1602	48/18639	0.0208333333333333	0.242392322097378	0.986692118206237	0.999999999933477
GO:0038187	pattern recognition receptor activity	1/1602	48/18639	0.0208333333333333	0.242392322097378	0.986692118206237	0.999999999933477
GO:0072341	modified amino acid binding	3/1602	91/18639	0.032967032967033	0.383565872329917	0.987303830205712	0.999999999933477
GO:0015293	symporter activity	6/1602	146/18639	0.0410958904109589	0.478143758657842	0.988730456466732	0.999999999933477
GO:0005272	sodium channel activity	1/1602	51/18639	0.0196078431372549	0.228133950209297	0.989844588589039	0.999999999933477
GO:0008509	monoatomic anion transmembrane transporter activity	6/1602	149/18639	0.0402684563758389	0.468516703114396	0.990560674826421	0.999999999933477
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	1/1602	52/18639	0.0192307692307692	0.223746758859118	0.990719829017292	0.999999999933477
GO:0098631	cell adhesion mediator activity	2/1602	76/18639	0.0263157894736842	0.306179775280899	0.991287546304326	0.999999999933477
GO:0005261	monoatomic cation channel activity	18/1602	341/18639	0.0527859237536657	0.614155326369897	0.992705258412844	0.999999999933477
GO:0098632	cell-cell adhesion mediator activity	1/1602	55/18639	0.0181818181818182	0.211542390194076	0.992918616369033	0.999999999933477
GO:0003823	antigen binding	7/1602	174/18639	0.0402298850574713	0.468067932325972	0.994123101058963	0.999999999933477
GO:0015079	potassium ion transmembrane transporter activity	6/1602	160/18639	0.0375	0.436306179775281	0.995141316211435	0.999999999933477
GO:0005267	potassium channel activity	4/1602	124/18639	0.032258064516129	0.375317143892715	0.995211420184118	0.999999999933477
GO:0015276	ligand-gated monoatomic ion channel activity	7/1602	186/18639	0.0376344086021505	0.437870001208167	0.997112308329324	0.999999999933477
GO:0022834	ligand-gated channel activity	7/1602	188/18639	0.0372340425531915	0.433211809705953	0.997440527280959	0.999999999933477
GO:0015294	solute:monoatomic cation symporter activity	3/1602	116/18639	0.0258620689655172	0.300900813638125	0.997941547033044	0.999999999933477
GO:0046873	metal ion transmembrane transporter activity	23/1602	450/18639	0.0511111111111111	0.594669163545568	0.998355219739296	0.999999999933477
GO:0030594	neurotransmitter receptor activity	2/1602	97/18639	0.0206185567010309	0.239893432178849	0.998373191766914	0.999999999933477
GO:0005249	voltage-gated potassium channel activity	2/1602	98/18639	0.0204081632653061	0.237445540013758	0.998499849547704	0.999999999933477
GO:0022836	gated channel activity	14/1602	318/18639	0.0440251572327044	0.512225284432196	0.998796993249193	0.999999999933477
GO:0004497	monooxygenase activity	2/1602	106/18639	0.0188679245283019	0.219525121899512	0.999218062556554	0.999999999933477
GO:0015081	sodium ion transmembrane transporter activity	4/1602	164/18639	0.024390243902439	0.283776377089614	0.999720306469978	0.999999999933477
GO:0005216	monoatomic ion channel activity	20/1602	448/18639	0.0446428571428571	0.519412118780096	0.999787033267334	0.999999999933477
GO:0030527	structural constituent of chromatin	1/1602	98/18639	0.0102040816326531	0.118722770006879	0.999853897130773	0.999999999933477
GO:0005179	hormone activity	2/1602	132/18639	0.0151515151515152	0.17628532516173	0.999908868298761	0.999999999933477
GO:0003735	structural constituent of ribosome	1/1602	175/18639	0.00571428571428571	0.0664847512038523	0.99999986314413	0.999999999933477
GO:0030371	translation repressor activity	4/1602	329/18639	0.0121580547112462	0.141456917455005	0.99999999937548	0.999999999933477
GO:0045182	translation regulator activity	4/1602	356/18639	0.0112359550561798	0.130728443378361	0.999999999933477	0.999999999933477