ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0048407	platelet-derived growth factor binding	5/465	11/18639	0.454545454545455	18.2199413489736	3.85983695158052e-06	0.00200463433092854
GO:0005201	extracellular matrix structural constituent	16/465	168/18639	0.0952380952380952	3.81751152073733	4.96196616566469e-06	0.00200463433092854
GO:0030020	extracellular matrix structural constituent conferring tensile strength	7/465	44/18639	0.159090909090909	6.37697947214076	9.90967468747965e-05	0.0177125812054235
GO:0003725	double-stranded RNA binding	9/465	75/18639	0.12	4.81006451612903	0.00010113775865793	0.0177125812054235
GO:0042605	peptide antigen binding	7/465	45/18639	0.155555555555556	6.2352688172043	0.000114857942169071	0.0177125812054235
GO:0003712	transcription coregulator activity	27/465	495/18639	0.0545454545454545	2.18639296187683	0.000131529068357105	0.0177125812054235
GO:0003714	transcription corepressor activity	15/465	204/18639	0.0735294117647059	2.94734345351044	0.000193817726545124	0.0223721032926372
GO:0048020	CCR chemokine receptor binding	7/465	50/18639	0.14	5.61174193548387	0.000227097754072299	0.0229368731613022
GO:0097110	scaffold protein binding	8/465	70/18639	0.114285714285714	4.58101382488479	0.000344061182745324	0.0308890484064691
GO:0042277	peptide binding	16/465	249/18639	0.0642570281124498	2.57567042363	0.00054634175645647	0.0441444139216828
GO:0008009	chemokine activity	6/465	45/18639	0.133333333333333	5.34451612903226	0.000833422642664206	0.0612186813884253
GO:0016763	pentosyltransferase activity	6/465	49/18639	0.122448979591837	4.90822909809085	0.0013158148573269	0.0885982003933444
GO:0017046	peptide hormone binding	6/465	53/18639	0.113207547169811	4.53779671332928	0.00198684795147629	0.104293044003498
GO:0042379	chemokine receptor binding	7/465	72/18639	0.0972222222222222	3.89704301075269	0.00209429733831049	0.104293044003498
GO:0043394	proteoglycan binding	5/465	37/18639	0.135135135135135	5.41673931996513	0.00213380042484544	0.104293044003498
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	4/465	23/18639	0.173913043478261	6.9711079943899	0.00232335989116704	0.104293044003498
GO:0005158	insulin receptor binding	4/465	23/18639	0.173913043478261	6.9711079943899	0.00232335989116704	0.104293044003498
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	4/465	23/18639	0.173913043478261	6.9711079943899	0.00232335989116704	0.104293044003498
GO:0019955	cytokine binding	10/465	144/18639	0.0694444444444444	2.78360215053763	0.00333051598334275	0.135816550159265
GO:0001664	G protein-coupled receptor binding	16/465	297/18639	0.0538720538720539	2.15940045617465	0.0033664211375753	0.135816550159265
GO:0046332	SMAD binding	7/465	79/18639	0.0886075949367089	3.55173540220498	0.00355234672924121	0.135816550159265
GO:0004435	phosphatidylinositol phospholipase C activity	4/465	26/18639	0.153846153846154	6.16674937965261	0.00369797537562355	0.135816550159265
GO:0023026	MHC class II protein complex binding	4/465	27/18639	0.148148148148148	5.93835125448029	0.00425677081388093	0.149542209461556
GO:0004629	phospholipase C activity	4/465	29/18639	0.137931034482759	5.52880978865406	0.00553947931331752	0.186076273029977
GO:0140297	DNA-binding transcription factor binding	22/465	488/18639	0.0450819672131148	1.80705975674246	0.00575731042790771	0.186076273029977
GO:0016500	protein-hormone receptor activity	6/465	67/18639	0.0895522388059701	3.58960038517092	0.00645354367873414	0.188974838205965
GO:0003727	single-stranded RNA binding	7/465	89/18639	0.0786516853932584	3.1526640086988	0.00683497743237484	0.188974838205965
GO:0002020	protease binding	9/465	136/18639	0.0661764705882353	2.65260910815939	0.00713432661372702	0.188974838205965
GO:0005178	integrin binding	10/465	161/18639	0.062111801242236	2.48968142656782	0.0072604390439732	0.188974838205965
GO:0070717	poly-purine tract binding	4/465	32/18639	0.125	5.01048387096774	0.00790935775965248	0.188974838205965
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/465	17/18639	0.176470588235294	7.07362428842505	0.00808501726147067	0.188974838205965
GO:0019198	transmembrane receptor protein phosphatase activity	3/465	17/18639	0.176470588235294	7.07362428842505	0.00808501726147067	0.188974838205965
GO:0035401	histone H3Y41 kinase activity	8/465	115/18639	0.0695652173913043	2.78844319775596	0.00818546869182703	0.188974838205965
GO:0140801	histone H2AXY142 kinase activity	8/465	115/18639	0.0695652173913043	2.78844319775596	0.00818546869182703	0.188974838205965
GO:0004857	enzyme inhibitor activity	19/465	416/18639	0.0456730769230769	1.83075372208437	0.00867175520445157	0.188974838205965
GO:0042562	hormone binding	7/465	94/18639	0.074468085106383	2.98496911461908	0.00913857213389964	0.188974838205965
GO:0033218	amide binding	13/465	247/18639	0.0526315789473684	2.10967741935484	0.00938471732684455	0.188974838205965
GO:0042393	histone binding	13/465	247/18639	0.0526315789473684	2.10967741935484	0.00938471732684455	0.188974838205965
GO:0031690	adrenergic receptor binding	3/465	18/18639	0.166666666666667	6.68064516129032	0.0095248034565378	0.188974838205965
GO:0098641	cadherin binding involved in cell-cell adhesion	3/465	18/18639	0.166666666666667	6.68064516129032	0.0095248034565378	0.188974838205965
GO:0004867	serine-type endopeptidase inhibitor activity	7/465	95/18639	0.0736842105263158	2.95354838709677	0.00966011856539428	0.188974838205965
GO:0030414	peptidase inhibitor activity	10/465	169/18639	0.0591715976331361	2.37182668448177	0.0100457138531833	0.188974838205965
GO:0045296	cadherin binding	16/465	334/18639	0.0479041916167665	1.92018543558045	0.010056829260961	0.188974838205965
GO:0043395	heparan sulfate proteoglycan binding	3/465	19/18639	0.157894736842105	6.32903225806452	0.0111043755636079	0.203916714895345
GO:0098632	cell-cell adhesion mediator activity	5/465	55/18639	0.0909090909090909	3.64398826979472	0.0118238180663906	0.212303222169859
GO:0016004	phospholipase activator activity	3/465	20/18639	0.15	6.01258064516129	0.0128259764231624	0.225291064128593
GO:0023023	MHC protein complex binding	4/465	37/18639	0.108108108108108	4.3333914559721	0.0131788558568549	0.226564160262526
GO:0044389	ubiquitin-like protein ligase binding	15/465	322/18639	0.046583850931677	1.86726106992587	0.0156961838546101	0.264219094885937
GO:0031683	G-protein beta/gamma-subunit complex binding	3/465	22/18639	0.136363636363636	5.46598240469208	0.0167020235684536	0.26982693556277
GO:0008013	beta-catenin binding	7/465	106/18639	0.0660377358490566	2.64704808277541	0.0169142752003204	0.26982693556277
GO:0031072	heat shock protein binding	8/465	131/18639	0.0610687022900763	2.44786998276287	0.0170311555862639	0.26982693556277
GO:0015026	coreceptor activity	5/465	61/18639	0.0819672131147541	3.28556319407721	0.0179235441251308	0.278504301021263
GO:0042169	SH2 domain binding	4/465	41/18639	0.0975609756097561	3.91062155782848	0.0186998006289794	0.280315179554477
GO:0031681	G-protein beta-subunit binding	3/465	23/18639	0.130434782608696	5.22833099579243	0.0188588231200466	0.280315179554477
GO:0004866	endopeptidase inhibitor activity	9/465	161/18639	0.0559006211180124	2.24071328391104	0.0198631457786412	0.280315179554477
GO:0035198	miRNA binding	4/465	42/18639	0.0952380952380952	3.81751152073733	0.0202722879144416	0.280315179554477
GO:0042578	phosphoric ester hydrolase activity	16/465	363/18639	0.0440771349862259	1.76678219141562	0.0205389871220721	0.280315179554477
GO:0019838	growth factor binding	8/465	136/18639	0.0588235294117647	2.35787476280835	0.0208412736293895	0.280315179554477
GO:0140789	histone phosphatase activity	8/465	136/18639	0.0588235294117647	2.35787476280835	0.0208412736293895	0.280315179554477
GO:0035035	histone acetyltransferase binding	3/465	24/18639	0.125	5.01048387096774	0.0211624083574543	0.280315179554477
GO:0060229	lipase activator activity	3/465	24/18639	0.125	5.01048387096774	0.0211624083574543	0.280315179554477
GO:0008081	phosphoric diester hydrolase activity	6/465	87/18639	0.0689655172413793	2.76440489432703	0.0216208901068993	0.281769019457655
GO:0038024	cargo receptor activity	5/465	65/18639	0.0769230769230769	3.0833746898263	0.0229701486147023	0.282153011708341
GO:0008483	transaminase activity	3/465	25/18639	0.12	4.81006451612903	0.0236130410035411	0.282153011708341
GO:0004713	protein tyrosine kinase activity	8/465	140/18639	0.0571428571428571	2.2905069124424	0.0242970216257011	0.282153011708341
GO:0047429	nucleoside triphosphate diphosphatase activity	2/465	10/18639	0.2	8.01677419354839	0.0244772808298789	0.282153011708341
GO:0001221	transcription coregulator binding	7/465	115/18639	0.0608695652173913	2.43988779803647	0.025200514198353	0.282153011708341
GO:0008143	poly(A) binding	3/465	26/18639	0.115384615384615	4.62506203473945	0.0262106582593564	0.282153011708341
GO:0050750	low-density lipoprotein particle receptor binding	3/465	26/18639	0.115384615384615	4.62506203473945	0.0262106582593564	0.282153011708341
GO:0003713	transcription coactivator activity	12/465	256/18639	0.046875	1.8789314516129	0.0276040841289344	0.282153011708341
GO:0008201	heparin binding	9/465	172/18639	0.0523255813953488	2.09741185296324	0.0288893645371531	0.282153011708341
GO:0008266	poly(U) RNA binding	3/465	27/18639	0.111111111111111	4.45376344086022	0.0289548941900409	0.282153011708341
GO:0010854	adenylate cyclase regulator activity	2/465	11/18639	0.181818181818182	7.28797653958944	0.0294294823127115	0.282153011708341
GO:0035252	UDP-xylosyltransferase activity	2/465	11/18639	0.181818181818182	7.28797653958944	0.0294294823127115	0.282153011708341
GO:0042285	xylosyltransferase activity	2/465	11/18639	0.181818181818182	7.28797653958944	0.0294294823127115	0.282153011708341
GO:0050998	nitric-oxide synthase binding	2/465	11/18639	0.181818181818182	7.28797653958944	0.0294294823127115	0.282153011708341
GO:0004721	phosphoprotein phosphatase activity	9/465	175/18639	0.0514285714285714	2.06145622119816	0.031781430940349	0.282153011708341
GO:0004896	cytokine receptor activity	6/465	96/18639	0.0625	2.50524193548387	0.0330222664787643	0.282153011708341
GO:0001222	transcription corepressor binding	4/465	49/18639	0.0816326530612245	3.27215273206057	0.033532988377684	0.282153011708341
GO:0005004	GPI-linked ephrin receptor activity	4/465	49/18639	0.0816326530612245	3.27215273206057	0.033532988377684	0.282153011708341
GO:0005008	hepatocyte growth factor receptor activity	4/465	49/18639	0.0816326530612245	3.27215273206057	0.033532988377684	0.282153011708341
GO:0005009	insulin receptor activity	4/465	49/18639	0.0816326530612245	3.27215273206057	0.033532988377684	0.282153011708341
GO:0005011	macrophage colony-stimulating factor receptor activity	4/465	49/18639	0.0816326530612245	3.27215273206057	0.033532988377684	0.282153011708341
GO:0005018	platelet-derived growth factor alpha-receptor activity	4/465	49/18639	0.0816326530612245	3.27215273206057	0.033532988377684	0.282153011708341
GO:0005020	stem cell factor receptor activity	4/465	49/18639	0.0816326530612245	3.27215273206057	0.033532988377684	0.282153011708341
GO:0008288	boss receptor activity	4/465	49/18639	0.0816326530612245	3.27215273206057	0.033532988377684	0.282153011708341
GO:0036332	placental growth factor receptor activity	4/465	49/18639	0.0816326530612245	3.27215273206057	0.033532988377684	0.282153011708341
GO:0038062	protein tyrosine kinase collagen receptor activity	4/465	49/18639	0.0816326530612245	3.27215273206057	0.033532988377684	0.282153011708341
GO:0060175	brain-derived neurotrophic factor receptor activity	4/465	49/18639	0.0816326530612245	3.27215273206057	0.033532988377684	0.282153011708341
GO:0035497	cAMP response element binding	2/465	12/18639	0.166666666666667	6.68064516129032	0.0347415079692081	0.282153011708341
GO:0097677	STAT family protein binding	2/465	12/18639	0.166666666666667	6.68064516129032	0.0347415079692081	0.282153011708341
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	2/465	12/18639	0.166666666666667	6.68064516129032	0.0347415079692081	0.282153011708341
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	2/465	12/18639	0.166666666666667	6.68064516129032	0.0347415079692081	0.282153011708341
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	2/465	12/18639	0.166666666666667	6.68064516129032	0.0347415079692081	0.282153011708341
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	2/465	12/18639	0.166666666666667	6.68064516129032	0.0347415079692081	0.282153011708341
GO:0099604	ligand-gated calcium channel activity	3/465	29/18639	0.103448275862069	4.14660734149055	0.0348803640559292	0.282153011708341
GO:0005516	calmodulin binding	10/465	207/18639	0.0483091787439614	1.93641888733053	0.0353479188341339	0.282153011708341
GO:0005006	epidermal growth factor receptor activity	4/465	50/18639	0.08	3.20670967741936	0.0357562274463972	0.282153011708341
GO:0005007	fibroblast growth factor receptor activity	4/465	50/18639	0.08	3.20670967741936	0.0357562274463972	0.282153011708341
GO:0005017	platelet-derived growth factor receptor activity	4/465	50/18639	0.08	3.20670967741936	0.0357562274463972	0.282153011708341
GO:0005019	platelet-derived growth factor beta-receptor activity	4/465	50/18639	0.08	3.20670967741936	0.0357562274463972	0.282153011708341
GO:0001965	G-protein alpha-subunit binding	3/465	30/18639	0.1	4.00838709677419	0.0380595292377843	0.282153011708341
GO:0008187	poly-pyrimidine tract binding	3/465	30/18639	0.1	4.00838709677419	0.0380595292377843	0.282153011708341
GO:0016769	transferase activity, transferring nitrogenous groups	3/465	30/18639	0.1	4.00838709677419	0.0380595292377843	0.282153011708341
GO:0048019	receptor antagonist activity	3/465	30/18639	0.1	4.00838709677419	0.0380595292377843	0.282153011708341
GO:0070566	adenylyltransferase activity	3/465	30/18639	0.1	4.00838709677419	0.0380595292377843	0.282153011708341
GO:0005010	insulin-like growth factor receptor activity	4/465	51/18639	0.0784313725490196	3.1438330170778	0.0380627206388727	0.282153011708341
GO:0005021	vascular endothelial growth factor receptor activity	4/465	51/18639	0.0784313725490196	3.1438330170778	0.0380627206388727	0.282153011708341
GO:0005030	neurotrophin receptor activity	4/465	51/18639	0.0784313725490196	3.1438330170778	0.0380627206388727	0.282153011708341
GO:0044183	protein folding chaperone	5/465	75/18639	0.0666666666666667	2.67225806451613	0.0393308910297465	0.288903272291229
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/465	13/18639	0.153846153846154	6.16674937965261	0.0403924038256397	0.292635350771439
GO:0098631	cell adhesion mediator activity	5/465	76/18639	0.0657894736842105	2.63709677419355	0.0412741779831024	0.292635350771439
GO:0017147	Wnt-protein binding	3/465	31/18639	0.0967741935483871	3.87908428720083	0.0413812117505733	0.292635350771439
GO:0070325	lipoprotein particle receptor binding	3/465	31/18639	0.0967741935483871	3.87908428720083	0.0413812117505733	0.292635350771439
GO:0061135	endopeptidase regulator activity	9/465	184/18639	0.0489130434782609	1.96062412342216	0.0416498333399944	0.292635350771439
GO:0005003	ephrin receptor activity	4/465	53/18639	0.0754716981132075	3.02519780888618	0.0429258771712296	0.293933125036894
GO:0005005	transmembrane-ephrin receptor activity	4/465	53/18639	0.0754716981132075	3.02519780888618	0.0429258771712296	0.293933125036894
GO:0038064	collagen receptor activity	4/465	53/18639	0.0754716981132075	3.02519780888618	0.0429258771712296	0.293933125036894
GO:0019199	transmembrane receptor protein kinase activity	5/465	78/18639	0.0641025641025641	2.56947890818859	0.0453323324209366	0.306249055795191
GO:0003925	G protein activity	4/465	54/18639	0.0740740740740741	2.96917562724014	0.0454825330388898	0.306249055795191
GO:0019956	chemokine binding	3/465	33/18639	0.0909090909090909	3.64398826979472	0.0484455573745895	0.320852543923511
GO:0071889	14-3-3 protein binding	3/465	33/18639	0.0909090909090909	3.64398826979472	0.0484455573745895	0.320852543923511
GO:0019902	phosphatase binding	9/465	190/18639	0.0473684210526316	1.89870967741935	0.0492691574173049	0.323654302383597
GO:0001618	virus receptor activity	5/465	81/18639	0.0617283950617284	2.47431302270012	0.0518508229247733	0.334849520276227
GO:0050780	dopamine receptor binding	2/465	15/18639	0.133333333333333	5.34451612903226	0.052631050835496	0.334849520276227
GO:0120283	protein serine/threonine kinase binding	2/465	15/18639	0.133333333333333	5.34451612903226	0.052631050835496	0.334849520276227
GO:0140776	protein-containing complex destabilizing activity	2/465	15/18639	0.133333333333333	5.34451612903226	0.052631050835496	0.334849520276227
GO:0140272	exogenous protein binding	5/465	82/18639	0.0609756097560976	2.4441384736428	0.0541390056180684	0.34032747988745
GO:0016779	nucleotidyltransferase activity	7/465	136/18639	0.0514705882352941	2.06314041745731	0.0543344615166845	0.34032747988745
GO:0004620	phospholipase activity	6/465	109/18639	0.055045871559633	2.20645161290323	0.0554041542214296	0.343485978029664
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	14/465	349/18639	0.0401146131805158	1.60794897864867	0.0559131942919395	0.343485978029664
GO:0030165	PDZ domain binding	5/465	83/18639	0.0602409638554217	2.41469102215313	0.0564849016725299	0.343485978029664
GO:0061980	regulatory RNA binding	4/465	58/18639	0.0689655172413793	2.76440489432703	0.0565391523241898	0.343485978029664
GO:0061134	peptidase regulator activity	10/465	226/18639	0.0442477876106195	1.77362260919212	0.0577305343860161	0.346508297912882
GO:0051117	ATPase binding	5/465	84/18639	0.0595238095238095	2.38594470046083	0.0588884783962397	0.346508297912882
GO:0005521	lamin binding	2/465	16/18639	0.125	5.01048387096774	0.0591808726633387	0.346508297912882
GO:0015562	efflux transmembrane transporter activity	2/465	16/18639	0.125	5.01048387096774	0.0591808726633387	0.346508297912882
GO:0022858	alanine transmembrane transporter activity	2/465	16/18639	0.125	5.01048387096774	0.0591808726633387	0.346508297912882
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	18/465	484/18639	0.0371900826446281	1.49072247400693	0.0609113613965609	0.354074676319577
GO:0004714	transmembrane receptor protein tyrosine kinase activity	4/465	60/18639	0.0666666666666667	2.67225806451613	0.0625607433559004	0.361064861654053
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/465	17/18639	0.117647058823529	4.7157495256167	0.0659936533835878	0.367743944371993
GO:0015278	intracellularly gated calcium channel activity	2/465	17/18639	0.117647058823529	4.7157495256167	0.0659936533835878	0.367743944371993
GO:0031489	myosin V binding	2/465	17/18639	0.117647058823529	4.7157495256167	0.0659936533835878	0.367743944371993
GO:0046965	nuclear retinoid X receptor binding	2/465	17/18639	0.117647058823529	4.7157495256167	0.0659936533835878	0.367743944371993
GO:0070403	NAD+ binding	2/465	17/18639	0.117647058823529	4.7157495256167	0.0659936533835878	0.367743944371993
GO:0001216	DNA-binding transcription activator activity	18/465	491/18639	0.0366598778004073	1.46946981144471	0.0678421448526631	0.371283711361323
GO:0017124	SH3 domain binding	6/465	115/18639	0.0521739130434783	2.09133239831697	0.0682089826448418	0.371283711361323
GO:0005501	retinoid binding	3/465	38/18639	0.0789473684210526	3.16451612903226	0.068466922020838	0.371283711361323
GO:0019840	isoprenoid binding	3/465	38/18639	0.0789473684210526	3.16451612903226	0.068466922020838	0.371283711361323
GO:0019903	protein phosphatase binding	7/465	144/18639	0.0486111111111111	1.94852150537634	0.0693898939474642	0.371536152932252
GO:0005125	cytokine activity	10/465	234/18639	0.0427350427350427	1.71298593879239	0.0694331176890718	0.371536152932252
GO:0003823	antigen binding	8/465	174/18639	0.0459770114942529	1.84293659621802	0.0706131763160367	0.375364779364195
GO:0003924	GTPase activity	13/465	331/18639	0.0392749244712991	1.57429100477536	0.0726320105066307	0.378373242157506
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/465	18/18639	0.111111111111111	4.45376344086022	0.073052259624469	0.378373242157506
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/465	18/18639	0.111111111111111	4.45376344086022	0.073052259624469	0.378373242157506
GO:0034185	apolipoprotein binding	2/465	18/18639	0.111111111111111	4.45376344086022	0.073052259624469	0.378373242157506
GO:0031625	ubiquitin protein ligase binding	12/465	302/18639	0.0397350993377483	1.59273659474471	0.0769886121381908	0.39565987287605
GO:0140662	ATP-dependent protein folding chaperone	3/465	40/18639	0.075	3.00629032258065	0.0773691335574455	0.39565987287605
GO:0005096	GTPase activator activity	11/465	271/18639	0.040590405904059	1.62702059278657	0.0783104833012732	0.39795516042408
GO:0030506	ankyrin binding	2/465	19/18639	0.105263157894737	4.21935483870968	0.0803402459845703	0.400709375034153
GO:0046624	sphingolipid transporter activity	2/465	19/18639	0.105263157894737	4.21935483870968	0.0803402459845703	0.400709375034153
GO:0070003	threonine-type peptidase activity	2/465	19/18639	0.105263157894737	4.21935483870968	0.0803402459845703	0.400709375034153
GO:0016791	phosphatase activity	11/465	273/18639	0.0402930402930403	1.61510102800425	0.0814786045410013	0.403893941528399
GO:0005539	glycosaminoglycan binding	10/465	242/18639	0.0413223140495868	1.65635830445215	0.0825418308862661	0.404445467825494
GO:0051082	unfolded protein binding	6/465	121/18639	0.0495867768595041	1.98762996534258	0.0825909680584238	0.404445467825494
GO:0004175	endopeptidase activity	15/465	405/18639	0.037037037037037	1.48458781362007	0.0840036652621868	0.407060061750486
GO:0005126	cytokine receptor binding	11/465	275/18639	0.04	1.60335483870968	0.0847255458748663	0.407060061750486
GO:1901681	sulfur compound binding	11/465	275/18639	0.04	1.60335483870968	0.0847255458748663	0.407060061750486
GO:0008528	G protein-coupled peptide receptor activity	6/465	122/18639	0.0491803278688525	1.97133791644632	0.085140037668109	0.407060061750486
GO:0042056	chemoattractant activity	3/465	42/18639	0.0714285714285714	2.863133640553	0.0867492795441453	0.407909194511758
GO:0051879	Hsp90 protein binding	3/465	42/18639	0.0714285714285714	2.863133640553	0.0867492795441453	0.407909194511758
GO:0001972	retinoic acid binding	2/465	20/18639	0.1	4.00838709677419	0.0878418314913934	0.407909194511758
GO:0010851	cyclase regulator activity	2/465	20/18639	0.1	4.00838709677419	0.0878418314913934	0.407909194511758
GO:0015095	magnesium ion transmembrane transporter activity	2/465	20/18639	0.1	4.00838709677419	0.0878418314913934	0.407909194511758
GO:1990841	promoter-specific chromatin binding	4/465	68/18639	0.0588235294117647	2.35787476280835	0.0898249148099116	0.414734463808049
GO:0048156	tau protein binding	3/465	43/18639	0.0697674418604651	2.79654913728432	0.0916111937367759	0.420578662155199
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2/465	21/18639	0.0952380952380952	3.81751152073733	0.0955418768023169	0.428876869201512
GO:0001846	opsonin binding	2/465	21/18639	0.0952380952380952	3.81751152073733	0.0955418768023169	0.428876869201512
GO:0010314	phosphatidylinositol-5-phosphate binding	2/465	21/18639	0.0952380952380952	3.81751152073733	0.0955418768023169	0.428876869201512
GO:0051428	peptide hormone receptor binding	2/465	21/18639	0.0952380952380952	3.81751152073733	0.0955418768023169	0.428876869201512
GO:0030547	signaling receptor inhibitor activity	3/465	44/18639	0.0681818181818182	2.73299120234604	0.0965835926458961	0.431157695347426
GO:0004725	protein tyrosine phosphatase activity	5/465	98/18639	0.0510204081632653	2.04509545753785	0.098494633386677	0.4372728778925
GO:0001653	peptide receptor activity	6/465	128/18639	0.046875	1.8789314516129	0.101331112899644	0.444021543103441
GO:0004715	non-membrane spanning protein tyrosine kinase activity	3/465	45/18639	0.0666666666666667	2.67225806451613	0.10166334835908	0.444021543103441
GO:0140303	intramembrane lipid transporter activity	3/465	45/18639	0.0666666666666667	2.67225806451613	0.10166334835908	0.444021543103441
GO:0008093	cytoskeletal anchor activity	2/465	22/18639	0.0909090909090909	3.64398826979472	0.103425862125703	0.44929084192241
GO:0005518	collagen binding	4/465	72/18639	0.0555555555555556	2.22688172043011	0.105267360890564	0.454845067377412
GO:0019887	protein kinase regulator activity	10/465	255/18639	0.0392156862745098	1.5719165085389	0.106869266953277	0.457026036077481
GO:0016298	lipase activity	6/465	130/18639	0.0461538461538462	1.85002481389578	0.107063949141635	0.457026036077481
GO:0141003	histone H2AX kinase activity	13/465	354/18639	0.0367231638418079	1.47200656096227	0.107468993632081	0.457026036077481
GO:0070577	lysine-acetylated histone binding	2/465	23/18639	0.0869565217391304	3.48555399719495	0.111479865840528	0.471600689000766
GO:0140996	histone H3 kinase activity	13/465	357/18639	0.0364145658263305	1.45963675792898	0.112641034035847	0.474031018234188
GO:0035064	methylated histone binding	4/465	74/18639	0.0540540540540541	2.16669572798605	0.11341151891547	0.474800555874093
GO:0032266	phosphatidylinositol-3-phosphate binding	3/465	48/18639	0.0625	2.50524193548387	0.117514817921785	0.488765906977506
GO:0035173	histone kinase activity	13/465	360/18639	0.0361111111111111	1.44747311827957	0.117957118639373	0.488765906977506
GO:0019957	C-C chemokine binding	2/465	24/18639	0.0833333333333333	3.34032258064516	0.119690543793534	0.490913499417136
GO:0140033	acetylation-dependent protein binding	2/465	24/18639	0.0833333333333333	3.34032258064516	0.119690543793534	0.490913499417136
GO:0017022	myosin binding	4/465	76/18639	0.0526315789473684	2.10967741935484	0.121824569717906	0.494644484080744
GO:0140034	methylation-dependent protein binding	4/465	76/18639	0.0526315789473684	2.10967741935484	0.121824569717906	0.494644484080744
GO:0035254	glutamate receptor binding	3/465	49/18639	0.0612244897959184	2.45411454904542	0.122991893761618	0.496887250796936
GO:0001848	complement binding	2/465	25/18639	0.08	3.20670967741936	0.128045109253534	0.509657380674164
GO:0042974	nuclear retinoic acid receptor binding	2/465	25/18639	0.08	3.20670967741936	0.128045109253534	0.509657380674164
GO:0120020	cholesterol transfer activity	2/465	25/18639	0.08	3.20670967741936	0.128045109253534	0.509657380674164
GO:0016757	glycosyltransferase activity	10/465	267/18639	0.0374531835205993	1.50126857557086	0.132604357958064	0.525217260931941
GO:0070851	growth factor receptor binding	6/465	139/18639	0.0431654676258993	1.73023903457879	0.13485129254903	0.528202658137055
GO:0034237	protein kinase A regulatory subunit binding	2/465	26/18639	0.0769230769230769	3.0833746898263	0.136531313503049	0.528202658137055
GO:0070006	metalloaminopeptidase activity	2/465	26/18639	0.0769230769230769	3.0833746898263	0.136531313503049	0.528202658137055
GO:0070412	R-SMAD binding	2/465	26/18639	0.0769230769230769	3.0833746898263	0.136531313503049	0.528202658137055
GO:0004222	metalloendopeptidase activity	5/465	110/18639	0.0454545454545455	1.82199413489736	0.140738790706246	0.528202658137055
GO:0140030	modification-dependent protein binding	7/465	173/18639	0.0404624277456647	1.62189073279881	0.142593116923583	0.528202658137055
GO:0033192	calmodulin-dependent protein phosphatase activity	4/465	81/18639	0.0493827160493827	1.9794504181601	0.143963826009744	0.528202658137055
GO:0140791	histone H2AXS140 phosphatase activity	4/465	81/18639	0.0493827160493827	1.9794504181601	0.143963826009744	0.528202658137055
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	4/465	81/18639	0.0493827160493827	1.9794504181601	0.143963826009744	0.528202658137055
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	4/465	81/18639	0.0493827160493827	1.9794504181601	0.143963826009744	0.528202658137055
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	4/465	81/18639	0.0493827160493827	1.9794504181601	0.143963826009744	0.528202658137055
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	4/465	81/18639	0.0493827160493827	1.9794504181601	0.143963826009744	0.528202658137055
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	4/465	81/18639	0.0493827160493827	1.9794504181601	0.143963826009744	0.528202658137055
GO:1990439	MAP kinase serine/threonine phosphatase activity	4/465	81/18639	0.0493827160493827	1.9794504181601	0.143963826009744	0.528202658137055
GO:0005044	scavenger receptor activity	2/465	27/18639	0.0740740740740741	2.96917562724014	0.145137427048089	0.528202658137055
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	2/465	27/18639	0.0740740740740741	2.96917562724014	0.145137427048089	0.528202658137055
GO:0035255	ionotropic glutamate receptor binding	2/465	27/18639	0.0740740740740741	2.96917562724014	0.145137427048089	0.528202658137055
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	2/465	27/18639	0.0740740740740741	2.96917562724014	0.145137427048089	0.528202658137055
GO:0051018	protein kinase A binding	3/465	53/18639	0.0566037735849057	2.26889835666464	0.145778703916539	0.528202658137055
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	4/465	82/18639	0.0487804878048781	1.95531077891424	0.148570227055471	0.533532193159202
GO:0033549	MAP kinase phosphatase activity	4/465	82/18639	0.0487804878048781	1.95531077891424	0.148570227055471	0.533532193159202
GO:0004252	serine-type endopeptidase activity	7/465	176/18639	0.0397727272727273	1.59424486803519	0.151734895436117	0.535830150488534
GO:0005525	GTP binding	13/465	378/18639	0.0343915343915344	1.37854582693292	0.152819890360535	0.535830150488534
GO:0001540	amyloid-beta binding	4/465	83/18639	0.0481927710843374	1.9317528177225	0.153232775176126	0.535830150488534
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	4/465	83/18639	0.0481927710843374	1.9317528177225	0.153232775176126	0.535830150488534
GO:0046875	ephrin receptor binding	2/465	28/18639	0.0714285714285714	2.863133640553	0.153852221427401	0.535830150488534
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	2/465	28/18639	0.0714285714285714	2.863133640553	0.153852221427401	0.535830150488534
GO:0097718	disordered domain specific binding	2/465	28/18639	0.0714285714285714	2.863133640553	0.153852221427401	0.535830150488534
GO:0140313	molecular sequestering activity	3/465	55/18639	0.0545454545454545	2.18639296187683	0.157652865967603	0.545399965522296
GO:0017018	myosin phosphatase activity	4/465	84/18639	0.0476190476190476	1.90875576036866	0.15794999001512	0.545399965522296
GO:0015085	calcium ion transmembrane transporter activity	6/465	147/18639	0.0408163265306122	1.63607636603028	0.162109278680043	0.557379987972232
GO:0030170	pyridoxal phosphate binding	3/465	56/18639	0.0535714285714286	2.14735023041475	0.163698573331373	0.560459522253175
GO:1990782	protein tyrosine kinase binding	5/465	117/18639	0.0427350427350427	1.71298593879239	0.168471376299473	0.570472402646979
GO:0070279	vitamin B6 binding	3/465	57/18639	0.0526315789473684	2.10967741935484	0.169812323987365	0.570472402646979
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/465	30/18639	0.0666666666666667	2.67225806451613	0.171565338914871	0.570472402646979
GO:0031210	phosphatidylcholine binding	2/465	30/18639	0.0666666666666667	2.67225806451613	0.171565338914871	0.570472402646979
GO:0035925	mRNA 3'-UTR AU-rich region binding	2/465	30/18639	0.0666666666666667	2.67225806451613	0.171565338914871	0.570472402646979
GO:0051721	protein phosphatase 2A binding	2/465	30/18639	0.0666666666666667	2.67225806451613	0.171565338914871	0.570472402646979
GO:0098918	structural constituent of synapse	2/465	30/18639	0.0666666666666667	2.67225806451613	0.171565338914871	0.570472402646979
GO:0019207	kinase regulator activity	10/465	287/18639	0.0348432055749129	1.39665055636731	0.182069555159131	0.593955932701676
GO:0004879	nuclear receptor activity	3/465	59/18639	0.0508474576271186	2.03816293056315	0.182230948912678	0.593955932701676
GO:0070888	E-box binding	3/465	59/18639	0.0508474576271186	2.03816293056315	0.182230948912678	0.593955932701676
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	4/465	89/18639	0.0449438202247191	1.80152229068503	0.182303306076752	0.593955932701676
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	4/465	89/18639	0.0449438202247191	1.80152229068503	0.182303306076752	0.593955932701676
GO:0140793	histone H2AXY142 phosphatase activity	4/465	90/18639	0.0444444444444444	1.78150537634409	0.187316718591289	0.605489662508735
GO:0098531	ligand-modulated transcription factor activity	3/465	60/18639	0.05	2.0041935483871	0.188529380784087	0.605489662508735
GO:0071813	lipoprotein particle binding	2/465	32/18639	0.0625	2.50524193548387	0.189590203731077	0.605489662508735
GO:0071814	protein-lipid complex binding	2/465	32/18639	0.0625	2.50524193548387	0.189590203731077	0.605489662508735
GO:0120015	sterol transfer activity	2/465	32/18639	0.0625	2.50524193548387	0.189590203731077	0.605489662508735
GO:0140375	immune receptor activity	6/465	156/18639	0.0384615384615385	1.54168734491315	0.195326394968776	0.621353256436105
GO:0019001	guanyl nucleotide binding	13/465	400/18639	0.0325	1.30272580645161	0.201923086516333	0.637319741817175
GO:0032561	guanyl ribonucleotide binding	13/465	400/18639	0.0325	1.30272580645161	0.201923086516333	0.637319741817175
GO:0016410	N-acyltransferase activity	4/465	94/18639	0.0425531914893617	1.70569663692519	0.207794631316215	0.645944102512439
GO:0015020	glucuronosyltransferase activity	2/465	34/18639	0.0588235294117647	2.35787476280835	0.207853300313409	0.645944102512439
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/465	34/18639	0.0588235294117647	2.35787476280835	0.207853300313409	0.645944102512439
GO:0051427	hormone receptor binding	2/465	34/18639	0.0588235294117647	2.35787476280835	0.207853300313409	0.645944102512439
GO:0008236	serine-type peptidase activity	7/465	194/18639	0.0360824742268041	1.44632524110409	0.211821694602565	0.650737604154956
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	5/465	128/18639	0.0390625	1.56577620967742	0.215847823344286	0.650737604154956
GO:0005154	epidermal growth factor receptor binding	2/465	35/18639	0.0571428571428571	2.2905069124424	0.217052990936402	0.650737604154956
GO:0061659	ubiquitin-like protein ligase activity	12/465	372/18639	0.032258064516129	1.29302809573361	0.22095005254746	0.650737604154956
GO:0005522	profilin binding	1/465	10/18639	0.1	4.00838709677419	0.223301766656794	0.650737604154956
GO:0005528	FK506 binding	1/465	10/18639	0.1	4.00838709677419	0.223301766656794	0.650737604154956
GO:0008401	retinoic acid 4-hydroxylase activity	1/465	10/18639	0.1	4.00838709677419	0.223301766656794	0.650737604154956
GO:0008519	ammonium channel activity	1/465	10/18639	0.1	4.00838709677419	0.223301766656794	0.650737604154956
GO:0015187	glycine transmembrane transporter activity	1/465	10/18639	0.1	4.00838709677419	0.223301766656794	0.650737604154956
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/465	10/18639	0.1	4.00838709677419	0.223301766656794	0.650737604154956
GO:0030957	Tat protein binding	1/465	10/18639	0.1	4.00838709677419	0.223301766656794	0.650737604154956
GO:0033204	ribonuclease P RNA binding	1/465	10/18639	0.1	4.00838709677419	0.223301766656794	0.650737604154956
GO:0043208	glycosphingolipid binding	1/465	10/18639	0.1	4.00838709677419	0.223301766656794	0.650737604154956
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/465	10/18639	0.1	4.00838709677419	0.223301766656794	0.650737604154956
GO:0050815	phosphoserine residue binding	1/465	10/18639	0.1	4.00838709677419	0.223301766656794	0.650737604154956
GO:0140135	mechanosensitive monoatomic cation channel activity	1/465	10/18639	0.1	4.00838709677419	0.223301766656794	0.650737604154956
GO:0017171	serine hydrolase activity	7/465	198/18639	0.0353535353535354	1.41710654936461	0.226245211280192	0.650737604154956
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/465	36/18639	0.0555555555555556	2.22688172043011	0.226287572945505	0.650737604154956
GO:0005262	calcium channel activity	5/465	131/18639	0.0381679389312977	1.52991873922679	0.229441284833507	0.650737604154956
GO:0050840	extracellular matrix binding	3/465	67/18639	0.0447761194029851	1.79480019258546	0.233989362512832	0.650737604154956
GO:0043130	ubiquitin binding	4/465	100/18639	0.04	1.60335483870968	0.239613262087279	0.650737604154956
GO:0030695	GTPase regulator activity	15/465	489/18639	0.0306748466257669	1.22956659410251	0.241872324592002	0.650737604154956
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0001851	complement component C3b binding	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0008046	axon guidance receptor activity	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0008432	JUN kinase binding	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0032794	GTPase activating protein binding	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0042608	T cell receptor binding	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0043522	leucine zipper domain binding	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0045294	alpha-catenin binding	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0050786	RAGE receptor binding	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0070697	activin receptor binding	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0097493	structural molecule activity conferring elasticity	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0180030	inositol phosphate kinase activity	1/465	11/18639	0.0909090909090909	3.64398826979472	0.242688995091202	0.650737604154956
GO:0051087	protein-folding chaperone binding	5/465	134/18639	0.0373134328358209	1.49566682715455	0.243275151018989	0.650737604154956
GO:0016887	ATP hydrolysis activity	13/465	417/18639	0.0311750599520384	1.24961708052913	0.244147751902646	0.650737604154956
GO:0060589	nucleoside-triphosphatase regulator activity	15/465	490/18639	0.0306122448979592	1.22705727452271	0.244245574588138	0.650737604154956
GO:0042887	amide transmembrane transporter activity	2/465	38/18639	0.0526315789473684	2.10967741935484	0.244831969880082	0.650737604154956
GO:0008080	N-acetyltransferase activity	3/465	69/18639	0.0434782608695652	1.74277699859748	0.247327934085321	0.652921047160042
GO:0004722	protein serine/threonine phosphatase activity	4/465	103/18639	0.0388349514563107	1.55665518321328	0.255928004989819	0.652921047160042
GO:0016922	nuclear receptor binding	5/465	137/18639	0.0364963503649635	1.4629149988227	0.25732375892363	0.652921047160042
GO:0005543	phospholipid binding	15/465	497/18639	0.0301810865191147	1.20977477769845	0.261110402708031	0.652921047160042
GO:0003995	acyl-CoA dehydrogenase activity	1/465	12/18639	0.0833333333333333	3.34032258064516	0.261593312102292	0.652921047160042
GO:0004000	adenosine deaminase activity	1/465	12/18639	0.0833333333333333	3.34032258064516	0.261593312102292	0.652921047160042
GO:0004526	ribonuclease P activity	1/465	12/18639	0.0833333333333333	3.34032258064516	0.261593312102292	0.652921047160042
GO:0005095	GTPase inhibitor activity	1/465	12/18639	0.0833333333333333	3.34032258064516	0.261593312102292	0.652921047160042
GO:0005527	macrolide binding	1/465	12/18639	0.0833333333333333	3.34032258064516	0.261593312102292	0.652921047160042
GO:0008179	adenylate cyclase binding	1/465	12/18639	0.0833333333333333	3.34032258064516	0.261593312102292	0.652921047160042
GO:0010853	cyclase activator activity	1/465	12/18639	0.0833333333333333	3.34032258064516	0.261593312102292	0.652921047160042
GO:0015368	calcium:monoatomic cation antiporter activity	1/465	12/18639	0.0833333333333333	3.34032258064516	0.261593312102292	0.652921047160042
GO:0016273	arginine N-methyltransferase activity	1/465	12/18639	0.0833333333333333	3.34032258064516	0.261593312102292	0.652921047160042
GO:0016274	protein-arginine N-methyltransferase activity	1/465	12/18639	0.0833333333333333	3.34032258064516	0.261593312102292	0.652921047160042
GO:0035259	nuclear glucocorticoid receptor binding	1/465	12/18639	0.0833333333333333	3.34032258064516	0.261593312102292	0.652921047160042
GO:0042301	phosphate ion binding	1/465	12/18639	0.0833333333333333	3.34032258064516	0.261593312102292	0.652921047160042
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/465	12/18639	0.0833333333333333	3.34032258064516	0.261593312102292	0.652921047160042
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/465	12/18639	0.0833333333333333	3.34032258064516	0.261593312102292	0.652921047160042
GO:0070679	inositol 1,4,5 trisphosphate binding	1/465	12/18639	0.0833333333333333	3.34032258064516	0.261593312102292	0.652921047160042
GO:0004177	aminopeptidase activity	2/465	40/18639	0.05	2.0041935483871	0.263431016552195	0.652921047160042
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	2/465	40/18639	0.05	2.0041935483871	0.263431016552195	0.652921047160042
GO:0050997	quaternary ammonium group binding	2/465	40/18639	0.05	2.0041935483871	0.263431016552195	0.652921047160042
GO:0061630	ubiquitin protein ligase activity	11/465	353/18639	0.0311614730878187	1.24907246641689	0.268200424070392	0.653935233148209
GO:0001727	lipid kinase activity	2/465	41/18639	0.0487804878048781	1.95531077891424	0.272735123913889	0.653935233148209
GO:0015175	neutral L-amino acid transmembrane transporter activity	2/465	41/18639	0.0487804878048781	1.95531077891424	0.272735123913889	0.653935233148209
GO:0042287	MHC protein binding	2/465	41/18639	0.0487804878048781	1.95531077891424	0.272735123913889	0.653935233148209
GO:0140828	metal cation:monoatomic cation antiporter activity	2/465	41/18639	0.0487804878048781	1.95531077891424	0.272735123913889	0.653935233148209
GO:0035091	phosphatidylinositol binding	9/465	284/18639	0.0316901408450704	1.27026351658337	0.279567246423132	0.653935233148209
GO:0004465	lipoprotein lipase activity	1/465	13/18639	0.0769230769230769	3.0833746898263	0.280026721125347	0.653935233148209
GO:0004535	poly(A)-specific ribonuclease activity	1/465	13/18639	0.0769230769230769	3.0833746898263	0.280026721125347	0.653935233148209
GO:0008035	high-density lipoprotein particle binding	1/465	13/18639	0.0769230769230769	3.0833746898263	0.280026721125347	0.653935233148209
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/465	13/18639	0.0769230769230769	3.0833746898263	0.280026721125347	0.653935233148209
GO:0019855	calcium channel inhibitor activity	1/465	13/18639	0.0769230769230769	3.0833746898263	0.280026721125347	0.653935233148209
GO:0035673	oligopeptide transmembrane transporter activity	1/465	13/18639	0.0769230769230769	3.0833746898263	0.280026721125347	0.653935233148209
GO:0039706	co-receptor binding	1/465	13/18639	0.0769230769230769	3.0833746898263	0.280026721125347	0.653935233148209
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/465	13/18639	0.0769230769230769	3.0833746898263	0.280026721125347	0.653935233148209
GO:0046974	histone H3K9 methyltransferase activity	1/465	13/18639	0.0769230769230769	3.0833746898263	0.280026721125347	0.653935233148209
GO:0046975	histone H3K36 methyltransferase activity	1/465	13/18639	0.0769230769230769	3.0833746898263	0.280026721125347	0.653935233148209
GO:0051011	microtubule minus-end binding	1/465	13/18639	0.0769230769230769	3.0833746898263	0.280026721125347	0.653935233148209
GO:0061459	L-arginine transmembrane transporter activity	1/465	13/18639	0.0769230769230769	3.0833746898263	0.280026721125347	0.653935233148209
GO:0071837	HMG box domain binding	1/465	13/18639	0.0769230769230769	3.0833746898263	0.280026721125347	0.653935233148209
GO:0140852	histone ubiquitin ligase activity	1/465	13/18639	0.0769230769230769	3.0833746898263	0.280026721125347	0.653935233148209
GO:0048487	beta-tubulin binding	2/465	42/18639	0.0476190476190476	1.90875576036866	0.282034416132376	0.656725672146859
GO:0004712	protein serine/threonine/tyrosine kinase activity	2/465	43/18639	0.0465116279069767	1.86436609152288	0.29132335381021	0.661496565144198
GO:0106310	protein serine kinase activity	11/465	361/18639	0.0304709141274238	1.2213921901528	0.292028400806201	0.661496565144198
GO:0051536	iron-sulfur cluster binding	3/465	76/18639	0.0394736842105263	1.58225806451613	0.294762147987896	0.661496565144198
GO:0004705	JUN kinase activity	1/465	14/18639	0.0714285714285714	2.863133640553	0.29800092786199	0.661496565144198
GO:0005161	platelet-derived growth factor receptor binding	1/465	14/18639	0.0714285714285714	2.863133640553	0.29800092786199	0.661496565144198
GO:0008191	metalloendopeptidase inhibitor activity	1/465	14/18639	0.0714285714285714	2.863133640553	0.29800092786199	0.661496565144198
GO:0008195	phosphatidate phosphatase activity	1/465	14/18639	0.0714285714285714	2.863133640553	0.29800092786199	0.661496565144198
GO:0008559	ABC-type xenobiotic transporter activity	1/465	14/18639	0.0714285714285714	2.863133640553	0.29800092786199	0.661496565144198
GO:0031404	chloride ion binding	1/465	14/18639	0.0714285714285714	2.863133640553	0.29800092786199	0.661496565144198
GO:0034236	protein kinase A catalytic subunit binding	1/465	14/18639	0.0714285714285714	2.863133640553	0.29800092786199	0.661496565144198
GO:0042813	Wnt receptor activity	1/465	14/18639	0.0714285714285714	2.863133640553	0.29800092786199	0.661496565144198
GO:0043176	amine binding	1/465	14/18639	0.0714285714285714	2.863133640553	0.29800092786199	0.661496565144198
GO:0044548	S100 protein binding	1/465	14/18639	0.0714285714285714	2.863133640553	0.29800092786199	0.661496565144198
GO:0061665	SUMO ligase activity	1/465	14/18639	0.0714285714285714	2.863133640553	0.29800092786199	0.661496565144198
GO:0071933	Arp2/3 complex binding	1/465	14/18639	0.0714285714285714	2.863133640553	0.29800092786199	0.661496565144198
GO:0098847	sequence-specific single stranded DNA binding	1/465	14/18639	0.0714285714285714	2.863133640553	0.29800092786199	0.661496565144198
GO:1901612	cardiolipin binding	1/465	14/18639	0.0714285714285714	2.863133640553	0.29800092786199	0.661496565144198
GO:1902936	phosphatidylinositol bisphosphate binding	4/465	111/18639	0.036036036036036	1.44446381865737	0.300380139295044	0.662205709601124
GO:0001046	core promoter sequence-specific DNA binding	2/465	44/18639	0.0454545454545455	1.82199413489736	0.300596675770416	0.662205709601124
GO:0003724	RNA helicase activity	3/465	77/18639	0.038961038961039	1.56170925848345	0.301598640016353	0.662205709601124
GO:0051540	metal cluster binding	3/465	77/18639	0.038961038961039	1.56170925848345	0.301598640016353	0.662205709601124
GO:0005200	structural constituent of cytoskeleton	4/465	112/18639	0.0357142857142857	1.4315668202765	0.30600726709159	0.662358122428805
GO:0051539	4 iron, 4 sulfur cluster binding	2/465	45/18639	0.0444444444444444	1.78150537634409	0.309849388673269	0.662358122428805
GO:0008237	metallopeptidase activity	6/465	184/18639	0.0326086956521739	1.30708274894811	0.31129497112988	0.662358122428805
GO:0008186	ATP-dependent activity, acting on RNA	3/465	79/18639	0.0379746835443038	1.52217231523071	0.315292116418508	0.662358122428805
GO:0033293	monocarboxylic acid binding	3/465	79/18639	0.0379746835443038	1.52217231523071	0.315292116418508	0.662358122428805
GO:0004129	cytochrome-c oxidase activity	1/465	15/18639	0.0666666666666667	2.67225806451613	0.315527347649596	0.662358122428805
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	1/465	15/18639	0.0666666666666667	2.67225806451613	0.315527347649596	0.662358122428805
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	1/465	15/18639	0.0666666666666667	2.67225806451613	0.315527347649596	0.662358122428805
GO:0005523	tropomyosin binding	1/465	15/18639	0.0666666666666667	2.67225806451613	0.315527347649596	0.662358122428805
GO:0008242	omega peptidase activity	1/465	15/18639	0.0666666666666667	2.67225806451613	0.315527347649596	0.662358122428805
GO:0031386	protein tag activity	1/465	15/18639	0.0666666666666667	2.67225806451613	0.315527347649596	0.662358122428805
GO:0033130	acetylcholine receptor binding	1/465	15/18639	0.0666666666666667	2.67225806451613	0.315527347649596	0.662358122428805
GO:0047372	monoacylglycerol lipase activity	1/465	15/18639	0.0666666666666667	2.67225806451613	0.315527347649596	0.662358122428805
GO:0051371	muscle alpha-actinin binding	1/465	15/18639	0.0666666666666667	2.67225806451613	0.315527347649596	0.662358122428805
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/465	15/18639	0.0666666666666667	2.67225806451613	0.315527347649596	0.662358122428805
GO:0141047	molecular tag activity	1/465	15/18639	0.0666666666666667	2.67225806451613	0.315527347649596	0.662358122428805
GO:1901981	phosphatidylinositol phosphate binding	6/465	185/18639	0.0324324324324324	1.30001743679163	0.315671835395184	0.662358122428805
GO:0046982	protein heterodimerization activity	11/465	369/18639	0.029810298102981	1.19491214266981	0.316423558487028	0.662358122428805
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	2/465	46/18639	0.0434782608695652	1.74277699859748	0.319076756976183	0.664469122775144
GO:0030291	protein serine/threonine kinase inhibitor activity	2/465	46/18639	0.0434782608695652	1.74277699859748	0.319076756976183	0.664469122775144
GO:0048306	calcium-dependent protein binding	3/465	80/18639	0.0375	1.50314516129032	0.322144470211413	0.668193565481428
GO:0140359	ABC-type transporter activity	2/465	47/18639	0.0425531914893617	1.70569663692519	0.328274293226103	0.668193565481428
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	1/465	16/18639	0.0625	2.50524193548387	0.33261711264868	0.668193565481428
GO:0004707	MAP kinase activity	1/465	16/18639	0.0625	2.50524193548387	0.33261711264868	0.668193565481428
GO:0004708	MAP kinase kinase activity	1/465	16/18639	0.0625	2.50524193548387	0.33261711264868	0.668193565481428
GO:0005024	transforming growth factor beta receptor activity	1/465	16/18639	0.0625	2.50524193548387	0.33261711264868	0.668193565481428
GO:0005149	interleukin-1 receptor binding	1/465	16/18639	0.0625	2.50524193548387	0.33261711264868	0.668193565481428
GO:0005159	insulin-like growth factor receptor binding	1/465	16/18639	0.0625	2.50524193548387	0.33261711264868	0.668193565481428
GO:0015378	sodium:chloride symporter activity	1/465	16/18639	0.0625	2.50524193548387	0.33261711264868	0.668193565481428
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/465	16/18639	0.0625	2.50524193548387	0.33261711264868	0.668193565481428
GO:0017070	U6 snRNA binding	1/465	16/18639	0.0625	2.50524193548387	0.33261711264868	0.668193565481428
GO:0030275	LRR domain binding	1/465	16/18639	0.0625	2.50524193548387	0.33261711264868	0.668193565481428
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/465	16/18639	0.0625	2.50524193548387	0.33261711264868	0.668193565481428
GO:0140328	floppase activity	1/465	16/18639	0.0625	2.50524193548387	0.33261711264868	0.668193565481428
GO:0043177	organic acid binding	6/465	189/18639	0.0317460317460317	1.27250384024578	0.333269810506207	0.668193565481428
GO:0019208	phosphatase regulator activity	4/465	117/18639	0.0341880341880342	1.37038875103391	0.334280989891568	0.668561979783135
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	2/465	48/18639	0.0416666666666667	1.67016129032258	0.337437748674117	0.673209138095523
GO:0004549	tRNA-specific ribonuclease activity	1/465	17/18639	0.0588235294117647	2.35787476280835	0.349281078852748	0.687173244887849
GO:0030548	acetylcholine receptor regulator activity	1/465	17/18639	0.0588235294117647	2.35787476280835	0.349281078852748	0.687173244887849
GO:0051787	misfolded protein binding	1/465	17/18639	0.0588235294117647	2.35787476280835	0.349281078852748	0.687173244887849
GO:1990226	histone methyltransferase binding	1/465	17/18639	0.0588235294117647	2.35787476280835	0.349281078852748	0.687173244887849
GO:0004527	exonuclease activity	3/465	84/18639	0.0357142857142857	1.4315668202765	0.349539856001121	0.687173244887849
GO:0004860	protein kinase inhibitor activity	3/465	84/18639	0.0357142857142857	1.4315668202765	0.349539856001121	0.687173244887849
GO:0032182	ubiquitin-like protein binding	4/465	120/18639	0.0333333333333333	1.33612903225806	0.351308282249755	0.688973524412141
GO:0016755	aminoacyltransferase activity	14/465	496/18639	0.0282258064516129	1.13139958376691	0.356650267659287	0.696575719347642
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/465	18/18639	0.0555555555555556	2.22688172043011	0.365529832925	0.696575719347642
GO:0004706	JUN kinase kinase kinase activity	1/465	18/18639	0.0555555555555556	2.22688172043011	0.365529832925	0.696575719347642
GO:0004970	glutamate-gated receptor activity	1/465	18/18639	0.0555555555555556	2.22688172043011	0.365529832925	0.696575719347642
GO:0008525	phosphatidylcholine transporter activity	1/465	18/18639	0.0555555555555556	2.22688172043011	0.365529832925	0.696575719347642
GO:0015373	monoatomic anion:sodium symporter activity	1/465	18/18639	0.0555555555555556	2.22688172043011	0.365529832925	0.696575719347642
GO:0017128	phospholipid scramblase activity	1/465	18/18639	0.0555555555555556	2.22688172043011	0.365529832925	0.696575719347642
GO:0050811	GABA receptor binding	1/465	18/18639	0.0555555555555556	2.22688172043011	0.365529832925	0.696575719347642
GO:0070064	proline-rich region binding	1/465	18/18639	0.0555555555555556	2.22688172043011	0.365529832925	0.696575719347642
GO:0099602	neurotransmitter receptor regulator activity	1/465	18/18639	0.0555555555555556	2.22688172043011	0.365529832925	0.696575719347642
GO:1901611	phosphatidylglycerol binding	1/465	18/18639	0.0555555555555556	2.22688172043011	0.365529832925	0.696575719347642
GO:1990381	ubiquitin-specific protease binding	1/465	18/18639	0.0555555555555556	2.22688172043011	0.365529832925	0.696575719347642
GO:0005080	protein kinase C binding	2/465	52/18639	0.0384615384615385	1.54168734491315	0.373673642414276	0.710419536637023
GO:0008381	mechanosensitive monoatomic ion channel activity	1/465	19/18639	0.0526315789473684	2.10967741935484	0.381373698866135	0.717284094318721
GO:0016918	retinal binding	1/465	19/18639	0.0526315789473684	2.10967741935484	0.381373698866135	0.717284094318721
GO:0042577	lipid phosphatase activity	1/465	19/18639	0.0526315789473684	2.10967741935484	0.381373698866135	0.717284094318721
GO:0097001	ceramide binding	1/465	19/18639	0.0526315789473684	2.10967741935484	0.381373698866135	0.717284094318721
GO:0005246	calcium channel regulator activity	2/465	53/18639	0.0377358490566038	1.51259890444309	0.382610698825951	0.717284094318721
GO:0034212	protein N-acetyltransferase activity	2/465	53/18639	0.0377358490566038	1.51259890444309	0.382610698825951	0.717284094318721
GO:0019210	kinase inhibitor activity	3/465	90/18639	0.0333333333333333	1.33612903225806	0.390367783443366	0.72551859516746
GO:0042826	histone deacetylase binding	4/465	127/18639	0.031496062992126	1.26248412496825	0.391005525709749	0.72551859516746
GO:0001217	DNA-binding transcription repressor activity	8/465	278/18639	0.0287769784172662	1.15349268971919	0.391435434978686	0.72551859516746
GO:0051287	NAD binding	2/465	54/18639	0.037037037037037	1.48458781362007	0.391492707293332	0.72551859516746
GO:0140463	chromatin-protein adaptor activity	2/465	54/18639	0.037037037037037	1.48458781362007	0.391492707293332	0.72551859516746
GO:0004674	protein serine/threonine kinase activity	12/465	433/18639	0.0277136258660508	1.11086940326306	0.396523523615455	0.727058452539886
GO:0001614	purinergic nucleotide receptor activity	1/465	20/18639	0.05	2.0041935483871	0.396822744517438	0.727058452539886
GO:0016502	nucleotide receptor activity	1/465	20/18639	0.05	2.0041935483871	0.396822744517438	0.727058452539886
GO:0042288	MHC class I protein binding	1/465	20/18639	0.05	2.0041935483871	0.396822744517438	0.727058452539886
GO:0140939	histone H4 methyltransferase activity	1/465	20/18639	0.05	2.0041935483871	0.396822744517438	0.727058452539886
GO:0015399	primary active transmembrane transporter activity	5/465	166/18639	0.0301204819277108	1.20734551107656	0.399190932717884	0.728695403721897
GO:0043178	alcohol binding	3/465	92/18639	0.0326086956521739	1.30708274894811	0.403847128417421	0.728695403721897
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	4/465	130/18639	0.0307692307692308	1.23334987593052	0.407929771418877	0.728695403721897
GO:0008373	sialyltransferase activity	1/465	21/18639	0.0476190476190476	1.90875576036866	0.411886787903194	0.728695403721897
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/465	21/18639	0.0476190476190476	1.90875576036866	0.411886787903194	0.728695403721897
GO:0015174	basic amino acid transmembrane transporter activity	1/465	21/18639	0.0476190476190476	1.90875576036866	0.411886787903194	0.728695403721897
GO:0019200	carbohydrate kinase activity	1/465	21/18639	0.0476190476190476	1.90875576036866	0.411886787903194	0.728695403721897
GO:0036122	BMP binding	1/465	21/18639	0.0476190476190476	1.90875576036866	0.411886787903194	0.728695403721897
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/465	21/18639	0.0476190476190476	1.90875576036866	0.411886787903194	0.728695403721897
GO:0051010	microtubule plus-end binding	1/465	21/18639	0.0476190476190476	1.90875576036866	0.411886787903194	0.728695403721897
GO:0070182	DNA polymerase binding	1/465	21/18639	0.0476190476190476	1.90875576036866	0.411886787903194	0.728695403721897
GO:0019787	ubiquitin-like protein transferase activity	13/465	479/18639	0.0271398747390397	1.08787123712034	0.418111192551278	0.728695403721897
GO:0008276	protein methyltransferase activity	3/465	95/18639	0.0315789473684211	1.2658064516129	0.423898854694985	0.728695403721897
GO:0005243	gap junction channel activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0008970	phospholipase A1 activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0015377	chloride:monoatomic cation symporter activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0032931	histone H3K56 acetyltransferase activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0043992	histone H3K9 acetyltransferase activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0043993	histone H3K18 acetyltransferase activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0043994	histone H3K23 acetyltransferase activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0043999	histone H2AK5 acetyltransferase activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0044012	histone H2AK9 acetyltransferase activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0044014	histone H2BK5 acetyltransferase activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0044015	histone H2BK12 acetyltransferase activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0044016	histone H3K4 acetyltransferase activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0044017	histone H3K27 acetyltransferase activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0044018	histone H3K36 acetyltransferase activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0046972	histone H4K16 acetyltransferase activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0140517	protein-RNA adaptor activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0140908	histone H3K122 acetyltransferase activity	1/465	22/18639	0.0454545454545455	1.82199413489736	0.426575403416408	0.728695403721897
GO:0016407	acetyltransferase activity	3/465	96/18639	0.03125	1.25262096774194	0.430532160943077	0.733902924139254
GO:0045309	protein phosphorylated amino acid binding	2/465	59/18639	0.0338983050847458	1.3587752870421	0.434984435242668	0.735059361523
GO:0004602	glutathione peroxidase activity	1/465	23/18639	0.0434782608695652	1.74277699859748	0.440897927851675	0.735059361523
GO:0005283	amino acid:sodium symporter activity	1/465	23/18639	0.0434782608695652	1.74277699859748	0.440897927851675	0.735059361523
GO:0016493	C-C chemokine receptor activity	1/465	23/18639	0.0434782608695652	1.74277699859748	0.440897927851675	0.735059361523
GO:0044013	histone H2B acetyltransferase activity	1/465	23/18639	0.0434782608695652	1.74277699859748	0.440897927851675	0.735059361523
GO:0099186	structural constituent of postsynapse	1/465	23/18639	0.0434782608695652	1.74277699859748	0.440897927851675	0.735059361523
GO:0044325	transmembrane transporter binding	4/465	136/18639	0.0294117647058824	1.17893738140417	0.441467406815156	0.735059361523
GO:0099094	ligand-gated monoatomic cation channel activity	4/465	136/18639	0.0294117647058824	1.17893738140417	0.441467406815156	0.735059361523
GO:0008170	N-methyltransferase activity	3/465	98/18639	0.0306122448979592	1.22705727452271	0.443714482784594	0.735059361523
GO:0042626	ATPase-coupled transmembrane transporter activity	3/465	98/18639	0.0306122448979592	1.22705727452271	0.443714482784594	0.735059361523
GO:0004842	ubiquitin-protein transferase activity	12/465	449/18639	0.0267260579064588	1.07128385659889	0.445329630732791	0.735059361523
GO:0046873	metal ion transmembrane transporter activity	12/465	450/18639	0.0266666666666667	1.06890322580645	0.448376816060103	0.735059361523
GO:0019905	syntaxin binding	2/465	61/18639	0.0327868852459016	1.31422527763088	0.451910000919692	0.735059361523
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/465	24/18639	0.0416666666666667	1.67016129032258	0.454863466288985	0.735059361523
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/465	24/18639	0.0416666666666667	1.67016129032258	0.454863466288985	0.735059361523
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/465	24/18639	0.0416666666666667	1.67016129032258	0.454863466288985	0.735059361523
GO:0004806	triacylglycerol lipase activity	1/465	24/18639	0.0416666666666667	1.67016129032258	0.454863466288985	0.735059361523
GO:0015149	hexose transmembrane transporter activity	1/465	24/18639	0.0416666666666667	1.67016129032258	0.454863466288985	0.735059361523
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/465	24/18639	0.0416666666666667	1.67016129032258	0.454863466288985	0.735059361523
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/465	24/18639	0.0416666666666667	1.67016129032258	0.454863466288985	0.735059361523
GO:0043998	histone H2A acetyltransferase activity	1/465	24/18639	0.0416666666666667	1.67016129032258	0.454863466288985	0.735059361523
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/465	24/18639	0.0416666666666667	1.67016129032258	0.454863466288985	0.735059361523
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/465	24/18639	0.0416666666666667	1.67016129032258	0.454863466288985	0.735059361523
GO:0050431	transforming growth factor beta binding	1/465	24/18639	0.0416666666666667	1.67016129032258	0.454863466288985	0.735059361523
GO:0055056	D-glucose transmembrane transporter activity	1/465	24/18639	0.0416666666666667	1.67016129032258	0.454863466288985	0.735059361523
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/465	24/18639	0.0416666666666667	1.67016129032258	0.454863466288985	0.735059361523
GO:0030295	protein kinase activator activity	4/465	139/18639	0.0287769784172662	1.15349268971919	0.45802975154521	0.735792196117579
GO:0140767	enzyme-substrate adaptor activity	4/465	139/18639	0.0287769784172662	1.15349268971919	0.45802975154521	0.735792196117579
GO:0005319	lipid transporter activity	5/465	178/18639	0.0280898876404494	1.12595143167814	0.458048854761314	0.735792196117579
GO:0015179	L-amino acid transmembrane transporter activity	2/465	62/18639	0.032258064516129	1.29302809573361	0.460264047874834	0.73584343291848
GO:0000030	mannosyltransferase activity	1/465	25/18639	0.04	1.60335483870968	0.468480897832129	0.73584343291848
GO:0004709	MAP kinase kinase kinase activity	1/465	25/18639	0.04	1.60335483870968	0.468480897832129	0.73584343291848
GO:0005251	delayed rectifier potassium channel activity	1/465	25/18639	0.04	1.60335483870968	0.468480897832129	0.73584343291848
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/465	25/18639	0.04	1.60335483870968	0.468480897832129	0.73584343291848
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/465	25/18639	0.04	1.60335483870968	0.468480897832129	0.73584343291848
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/465	25/18639	0.04	1.60335483870968	0.468480897832129	0.73584343291848
GO:0019707	protein-cysteine S-acyltransferase activity	1/465	25/18639	0.04	1.60335483870968	0.468480897832129	0.73584343291848
GO:1901682	sulfur compound transmembrane transporter activity	2/465	63/18639	0.0317460317460317	1.27250384024578	0.468543422781241	0.73584343291848
GO:0008238	exopeptidase activity	3/465	102/18639	0.0294117647058824	1.17893738140417	0.469706219323342	0.73584343291848
GO:0015171	amino acid transmembrane transporter activity	3/465	102/18639	0.0294117647058824	1.17893738140417	0.469706219323342	0.73584343291848
GO:0005261	monoatomic cation channel activity	9/465	341/18639	0.0263929618768328	1.0579320783275	0.479377750626154	0.73584343291848
GO:0003730	mRNA 3'-UTR binding	7/465	262/18639	0.0267175572519084	1.07094311745875	0.480821879837434	0.73584343291848
GO:0001637	G protein-coupled chemoattractant receptor activity	1/465	26/18639	0.0384615384615385	1.54168734491315	0.481758881205292	0.73584343291848
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/465	26/18639	0.0384615384615385	1.54168734491315	0.481758881205292	0.73584343291848
GO:0004950	chemokine receptor activity	1/465	26/18639	0.0384615384615385	1.54168734491315	0.481758881205292	0.73584343291848
GO:0005112	Notch binding	1/465	26/18639	0.0384615384615385	1.54168734491315	0.481758881205292	0.73584343291848
GO:0005227	calcium-activated cation channel activity	1/465	26/18639	0.0384615384615385	1.54168734491315	0.481758881205292	0.73584343291848
GO:0008066	glutamate receptor activity	1/465	26/18639	0.0384615384615385	1.54168734491315	0.481758881205292	0.73584343291848
GO:0015145	monosaccharide transmembrane transporter activity	1/465	26/18639	0.0384615384615385	1.54168734491315	0.481758881205292	0.73584343291848
GO:0019865	immunoglobulin binding	1/465	26/18639	0.0384615384615385	1.54168734491315	0.481758881205292	0.73584343291848
GO:0030247	polysaccharide binding	1/465	26/18639	0.0384615384615385	1.54168734491315	0.481758881205292	0.73584343291848
GO:0030507	spectrin binding	1/465	26/18639	0.0384615384615385	1.54168734491315	0.481758881205292	0.73584343291848
GO:0043548	phosphatidylinositol 3-kinase binding	1/465	26/18639	0.0384615384615385	1.54168734491315	0.481758881205292	0.73584343291848
GO:0050681	nuclear androgen receptor binding	1/465	26/18639	0.0384615384615385	1.54168734491315	0.481758881205292	0.73584343291848
GO:0052742	phosphatidylinositol kinase activity	1/465	26/18639	0.0384615384615385	1.54168734491315	0.481758881205292	0.73584343291848
GO:0120013	lipid transfer activity	2/465	65/18639	0.0307692307692308	1.23334987593052	0.484872362568763	0.739201639538794
GO:0008194	UDP-glycosyltransferase activity	4/465	145/18639	0.0275862068965517	1.10576195773081	0.490627037416405	0.739647573490104
GO:0008235	metalloexopeptidase activity	2/465	66/18639	0.0303030303030303	1.21466275659824	0.492919325061297	0.739647573490104
GO:0004364	glutathione transferase activity	1/465	27/18639	0.037037037037037	1.48458781362007	0.494705860211338	0.739647573490104
GO:0005104	fibroblast growth factor receptor binding	1/465	27/18639	0.037037037037037	1.48458781362007	0.494705860211338	0.739647573490104
GO:0005385	zinc ion transmembrane transporter activity	1/465	27/18639	0.037037037037037	1.48458781362007	0.494705860211338	0.739647573490104
GO:0008320	protein transmembrane transporter activity	1/465	27/18639	0.037037037037037	1.48458781362007	0.494705860211338	0.739647573490104
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	2/465	67/18639	0.0298507462686567	1.19653346172364	0.500886400832018	0.739647573490104
GO:0042054	histone methyltransferase activity	2/465	67/18639	0.0298507462686567	1.19653346172364	0.500886400832018	0.739647573490104
GO:0031406	carboxylic acid binding	5/465	187/18639	0.0267379679144385	1.07176125582198	0.501112565379631	0.739647573490104
GO:0019888	protein phosphatase regulator activity	3/465	107/18639	0.0280373831775701	1.12384684956286	0.501402853039788	0.739647573490104
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	7/465	268/18639	0.0261194029850746	1.04696677900818	0.504626762081949	0.739647573490104
GO:0019209	kinase activator activity	4/465	148/18639	0.027027027027027	1.08334786399303	0.506621389985214	0.739647573490104
GO:0016866	intramolecular transferase activity	1/465	28/18639	0.0357142857142857	1.4315668202765	0.507330069055188	0.739647573490104
GO:0019789	SUMO transferase activity	1/465	28/18639	0.0357142857142857	1.4315668202765	0.507330069055188	0.739647573490104
GO:0036408	histone H3K14 acetyltransferase activity	1/465	28/18639	0.0357142857142857	1.4315668202765	0.507330069055188	0.739647573490104
GO:0045499	chemorepellent activity	1/465	28/18639	0.0357142857142857	1.4315668202765	0.507330069055188	0.739647573490104
GO:0046625	sphingolipid binding	1/465	28/18639	0.0357142857142857	1.4315668202765	0.507330069055188	0.739647573490104
GO:0051119	sugar transmembrane transporter activity	1/465	28/18639	0.0357142857142857	1.4315668202765	0.507330069055188	0.739647573490104
GO:0051393	alpha-actinin binding	1/465	28/18639	0.0357142857142857	1.4315668202765	0.507330069055188	0.739647573490104
GO:0051537	2 iron, 2 sulfur cluster binding	1/465	28/18639	0.0357142857142857	1.4315668202765	0.507330069055188	0.739647573490104
GO:0051959	dynein light intermediate chain binding	1/465	28/18639	0.0357142857142857	1.4315668202765	0.507330069055188	0.739647573490104
GO:0004843	cysteine-type deubiquitinase activity	3/465	108/18639	0.0277777777777778	1.11344086021505	0.507626401750752	0.739647573490104
GO:0005548	phospholipid transporter activity	2/465	68/18639	0.0294117647058824	1.17893738140417	0.508772561273808	0.739647573490104
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	2/465	68/18639	0.0294117647058824	1.17893738140417	0.508772561273808	0.739647573490104
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	6/465	229/18639	0.0262008733624454	1.05023242710241	0.509429015409096	0.739647573490104
GO:0016279	protein-lysine N-methyltransferase activity	2/465	69/18639	0.0289855072463768	1.16185133239832	0.516576878503315	0.739647573490104
GO:0019842	vitamin binding	4/465	150/18639	0.0266666666666667	1.06890322580645	0.517159153609193	0.739647573490104
GO:0003785	actin monomer binding	1/465	29/18639	0.0344827586206897	1.38220244716351	0.519639537535621	0.739647573490104
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/465	29/18639	0.0344827586206897	1.38220244716351	0.519639537535621	0.739647573490104
GO:0005416	amino acid:monoatomic cation symporter activity	1/465	29/18639	0.0344827586206897	1.38220244716351	0.519639537535621	0.739647573490104
GO:0010484	histone H3 acetyltransferase activity	1/465	29/18639	0.0344827586206897	1.38220244716351	0.519639537535621	0.739647573490104
GO:0016417	S-acyltransferase activity	1/465	29/18639	0.0344827586206897	1.38220244716351	0.519639537535621	0.739647573490104
GO:0043236	laminin binding	1/465	29/18639	0.0344827586206897	1.38220244716351	0.519639537535621	0.739647573490104
GO:0051861	glycolipid binding	1/465	29/18639	0.0344827586206897	1.38220244716351	0.519639537535621	0.739647573490104
GO:0097472	cyclin-dependent protein kinase activity	1/465	29/18639	0.0344827586206897	1.38220244716351	0.519639537535621	0.739647573490104
GO:0106222	lncRNA binding	1/465	29/18639	0.0344827586206897	1.38220244716351	0.519639537535621	0.739647573490104
GO:0000510	H3-H4 histone complex chaperone activity	4/465	151/18639	0.0264900662251656	1.06182439649648	0.522388642805652	0.739647573490104
GO:0140584	chromatin extrusion motor activity	4/465	151/18639	0.0264900662251656	1.06182439649648	0.522388642805652	0.739647573490104
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	4/465	151/18639	0.0264900662251656	1.06182439649648	0.522388642805652	0.739647573490104
GO:0140849	ATP-dependent H2AZ histone chaperone activity	4/465	151/18639	0.0264900662251656	1.06182439649648	0.522388642805652	0.739647573490104
GO:0016278	lysine N-methyltransferase activity	2/465	70/18639	0.0285714285714286	1.1452534562212	0.524298520995279	0.739647573490104
GO:0015616	DNA translocase activity	4/465	152/18639	0.0263157894736842	1.05483870967742	0.527591094163226	0.739647573490104
GO:0140674	ATP-dependent histone chaperone activity	4/465	152/18639	0.0263157894736842	1.05483870967742	0.527591094163226	0.739647573490104
GO:0001968	fibronectin binding	1/465	30/18639	0.0333333333333333	1.33612903225806	0.53164209610875	0.739647573490104
GO:0022839	monoatomic ion-gated channel activity	1/465	30/18639	0.0333333333333333	1.33612903225806	0.53164209610875	0.739647573490104
GO:0031624	ubiquitin conjugating enzyme binding	1/465	30/18639	0.0333333333333333	1.33612903225806	0.53164209610875	0.739647573490104
GO:0033612	receptor serine/threonine kinase binding	1/465	30/18639	0.0333333333333333	1.33612903225806	0.53164209610875	0.739647573490104
GO:0043995	histone H4K5 acetyltransferase activity	1/465	30/18639	0.0333333333333333	1.33612903225806	0.53164209610875	0.739647573490104
GO:0043996	histone H4K8 acetyltransferase activity	1/465	30/18639	0.0333333333333333	1.33612903225806	0.53164209610875	0.739647573490104
GO:0043997	histone H4K12 acetyltransferase activity	1/465	30/18639	0.0333333333333333	1.33612903225806	0.53164209610875	0.739647573490104
GO:0140299	molecular sensor activity	2/465	71/18639	0.028169014084507	1.12912312585189	0.531936749371204	0.739647573490104
GO:0061775	cohesin loader activity	4/465	153/18639	0.0261437908496732	1.04794433902593	0.532765950211931	0.739647573490104
GO:0008017	microtubule binding	7/465	276/18639	0.0253623188405797	1.01661991584853	0.535781684772859	0.742558492789828
GO:0004386	helicase activity	4/465	155/18639	0.0258064516129032	1.03442247658689	0.543030743453086	0.744332192103222
GO:0005164	tumor necrosis factor receptor binding	1/465	31/18639	0.032258064516129	1.29302809573361	0.543345380826329	0.744332192103222
GO:0070273	phosphatidylinositol-4-phosphate binding	1/465	31/18639	0.032258064516129	1.29302809573361	0.543345380826329	0.744332192103222
GO:0072349	modified amino acid transmembrane transporter activity	1/465	31/18639	0.032258064516129	1.29302809573361	0.543345380826329	0.744332192103222
GO:0101005	deubiquitinase activity	3/465	115/18639	0.0260869565217391	1.04566619915849	0.550010259082385	0.744332192103222
GO:0031491	nucleosome binding	2/465	74/18639	0.027027027027027	1.08334786399303	0.554344853926139	0.744332192103222
GO:0022884	macromolecule transmembrane transporter activity	1/465	32/18639	0.03125	1.25262096774194	0.554756838151983	0.744332192103222
GO:0042910	xenobiotic transmembrane transporter activity	1/465	32/18639	0.03125	1.25262096774194	0.554756838151983	0.744332192103222
GO:0043425	bHLH transcription factor binding	1/465	32/18639	0.03125	1.25262096774194	0.554756838151983	0.744332192103222
GO:0140658	ATP-dependent chromatin remodeler activity	4/465	158/18639	0.0253164556962025	1.01478154348714	0.558208137512415	0.744332192103222
GO:0019239	deaminase activity	1/465	33/18639	0.0303030303030303	1.21466275659824	0.565883729658369	0.744332192103222
GO:0030296	protein tyrosine kinase activator activity	1/465	33/18639	0.0303030303030303	1.21466275659824	0.565883729658369	0.744332192103222
GO:0140311	protein sequestering activity	1/465	33/18639	0.0303030303030303	1.21466275659824	0.565883729658369	0.744332192103222
GO:0140416	transcription regulator inhibitor activity	1/465	33/18639	0.0303030303030303	1.21466275659824	0.565883729658369	0.744332192103222
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	6/465	243/18639	0.0246913580246914	0.989725209080048	0.56750472068077	0.744332192103222
GO:0022853	active monoatomic ion transmembrane transporter activity	3/465	118/18639	0.0254237288135593	1.01908146528157	0.567505041200009	0.744332192103222
GO:0003689	DNA clamp loader activity	4/465	160/18639	0.025	1.00209677419355	0.568174472130812	0.744332192103222
GO:0015079	potassium ion transmembrane transporter activity	4/465	160/18639	0.025	1.00209677419355	0.568174472130812	0.744332192103222
GO:0004676	3-phosphoinositide-dependent protein kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0004711	ribosomal protein S6 kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0035175	histone H3S10 kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0035979	histone H2AXS139 kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0044022	histone H3S28 kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0044023	histone H4S1 kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0044024	histone H2AS1 kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0044025	histone H2BS14 kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0072354	histone H3T3 kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0072371	histone H2AS121 kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0072518	Rho-dependent protein serine/threonine kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0140823	histone H2BS36 kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0140855	histone H3S57 kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0140995	histone H2A kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0140997	histone H4 kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0140998	histone H2B kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:1990244	histone H2AT120 kinase activity	6/465	245/18639	0.0244897959183673	0.98164581961817	0.575531641467628	0.744332192103222
GO:0008376	acetylgalactosaminyltransferase activity	1/465	34/18639	0.0294117647058824	1.17893738140417	0.576733136608216	0.744332192103222
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/465	34/18639	0.0294117647058824	1.17893738140417	0.576733136608216	0.744332192103222
GO:0016831	carboxy-lyase activity	1/465	34/18639	0.0294117647058824	1.17893738140417	0.576733136608216	0.744332192103222
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	1/465	34/18639	0.0294117647058824	1.17893738140417	0.576733136608216	0.744332192103222
GO:0019825	oxygen binding	1/465	34/18639	0.0294117647058824	1.17893738140417	0.576733136608216	0.744332192103222
GO:0030332	cyclin binding	1/465	34/18639	0.0294117647058824	1.17893738140417	0.576733136608216	0.744332192103222
GO:0090482	vitamin transmembrane transporter activity	1/465	34/18639	0.0294117647058824	1.17893738140417	0.576733136608216	0.744332192103222
GO:0008083	growth factor activity	4/465	162/18639	0.0246913580246914	0.989725209080048	0.57801532758134	0.744332192103222
GO:0004677	DNA-dependent protein kinase activity	6/465	246/18639	0.024390243902439	0.97765538945712	0.579517361196029	0.744332192103222
GO:0140857	histone H3T45 kinase activity	6/465	246/18639	0.024390243902439	0.97765538945712	0.579517361196029	0.744332192103222
GO:0035402	histone H3T11 kinase activity	6/465	247/18639	0.0242914979757085	0.973697270471464	0.583484244414467	0.744332192103222
GO:0035403	histone H3T6 kinase activity	6/465	247/18639	0.0242914979757085	0.973697270471464	0.583484244414467	0.744332192103222
GO:0003697	single-stranded DNA binding	3/465	121/18639	0.0247933884297521	0.993814982671288	0.58457653823904	0.744332192103222
GO:0000175	3'-5'-RNA exonuclease activity	1/465	35/18639	0.0285714285714286	1.1452534562212	0.587311964422093	0.744332192103222
GO:0005343	organic acid:sodium symporter activity	1/465	35/18639	0.0285714285714286	1.1452534562212	0.587311964422093	0.744332192103222
GO:0010485	histone H4 acetyltransferase activity	1/465	35/18639	0.0285714285714286	1.1452534562212	0.587311964422093	0.744332192103222
GO:0140566	histone reader activity	1/465	35/18639	0.0285714285714286	1.1452534562212	0.587311964422093	0.744332192103222
GO:0004679	AMP-activated protein kinase activity	6/465	248/18639	0.0241935483870968	0.969771071800208	0.587432043052841	0.744332192103222
GO:0015081	sodium ion transmembrane transporter activity	4/465	164/18639	0.024390243902439	0.97765538945712	0.58772764673497	0.744332192103222
GO:0140713	histone chaperone activity	4/465	164/18639	0.024390243902439	0.97765538945712	0.58772764673497	0.744332192103222
GO:0015370	solute:sodium symporter activity	2/465	79/18639	0.0253164556962025	1.01478154348714	0.58997826414274	0.7450238051649
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	3/465	122/18639	0.0245901639344262	0.985668958223162	0.590170946743121	0.7450238051649
GO:0022804	active transmembrane transporter activity	11/465	457/18639	0.0240700218818381	0.964819651302322	0.591039924641956	0.7450238051649
GO:0004190	aspartic-type endopeptidase activity	1/465	36/18639	0.0277777777777778	1.11344086021505	0.59762694703571	0.74518915618033
GO:0016409	palmitoyltransferase activity	1/465	36/18639	0.0277777777777778	1.11344086021505	0.59762694703571	0.74518915618033
GO:0044390	ubiquitin-like protein conjugating enzyme binding	1/465	36/18639	0.0277777777777778	1.11344086021505	0.59762694703571	0.74518915618033
GO:0055106	ubiquitin-protein transferase regulator activity	1/465	36/18639	0.0277777777777778	1.11344086021505	0.59762694703571	0.74518915618033
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	1/465	36/18639	0.0277777777777778	1.11344086021505	0.59762694703571	0.74518915618033
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	1/465	36/18639	0.0277777777777778	1.11344086021505	0.59762694703571	0.74518915618033
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	1/465	36/18639	0.0277777777777778	1.11344086021505	0.59762694703571	0.74518915618033
GO:0004518	nuclease activity	5/465	209/18639	0.0239234449760766	0.958944281524927	0.599942338598432	0.746923589503133
GO:0005267	potassium channel activity	3/465	124/18639	0.0241935483870968	0.969771071800208	0.601213433842478	0.747354545453418
GO:0015101	organic cation transmembrane transporter activity	2/465	81/18639	0.0246913580246914	0.989725209080048	0.603626765052339	0.749201883505822
GO:0022829	wide pore channel activity	1/465	37/18639	0.027027027027027	1.08334786399303	0.607684651149476	0.750778590410974
GO:0042805	actinin binding	1/465	37/18639	0.027027027027027	1.08334786399303	0.607684651149476	0.750778590410974
GO:0070001	aspartic-type peptidase activity	1/465	37/18639	0.027027027027027	1.08334786399303	0.607684651149476	0.750778590410974
GO:0019783	ubiquitin-like protein peptidase activity	3/465	127/18639	0.0236220472440945	0.946863093726187	0.617406823446758	0.758257015412405
GO:0005109	frizzled binding	1/465	38/18639	0.0263157894736842	1.05483870967742	0.617491480372973	0.758257015412405
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/465	38/18639	0.0263157894736842	1.05483870967742	0.617491480372973	0.758257015412405
GO:0042162	telomeric DNA binding	1/465	38/18639	0.0263157894736842	1.05483870967742	0.617491480372973	0.758257015412405
GO:0015631	tubulin binding	9/465	385/18639	0.0233766233766234	0.937025555090071	0.625465269817379	0.766504346214346
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	1/465	39/18639	0.0256410256410256	1.02779156327543	0.627053679266934	0.766504346214346
GO:0016776	phosphotransferase activity, phosphate group as acceptor	1/465	39/18639	0.0256410256410256	1.02779156327543	0.627053679266934	0.766504346214346
GO:0016209	antioxidant activity	2/465	86/18639	0.0232558139534884	0.93218304576144	0.636236139150623	0.768599235465607
GO:0050660	flavin adenine dinucleotide binding	2/465	86/18639	0.0232558139534884	0.93218304576144	0.636236139150623	0.768599235465607
GO:0004532	RNA exonuclease activity	1/465	40/18639	0.025	1.00209677419355	0.636377337285261	0.768599235465607
GO:0015144	carbohydrate transmembrane transporter activity	1/465	40/18639	0.025	1.00209677419355	0.636377337285261	0.768599235465607
GO:0030331	nuclear estrogen receptor binding	1/465	40/18639	0.025	1.00209677419355	0.636377337285261	0.768599235465607
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	1/465	40/18639	0.025	1.00209677419355	0.636377337285261	0.768599235465607
GO:0071855	neuropeptide receptor binding	1/465	40/18639	0.025	1.00209677419355	0.636377337285261	0.768599235465607
GO:0071949	FAD binding	1/465	40/18639	0.025	1.00209677419355	0.636377337285261	0.768599235465607
GO:0001530	lipopolysaccharide binding	1/465	41/18639	0.024390243902439	0.97765538945712	0.645468392619545	0.774945707632381
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	1/465	41/18639	0.024390243902439	0.97765538945712	0.645468392619545	0.774945707632381
GO:0008137	NADH dehydrogenase (ubiquinone) activity	1/465	41/18639	0.024390243902439	0.97765538945712	0.645468392619545	0.774945707632381
GO:0140318	protein transporter activity	1/465	41/18639	0.024390243902439	0.97765538945712	0.645468392619545	0.774945707632381
GO:0004402	histone acetyltransferase activity	1/465	42/18639	0.0238095238095238	0.954377880184332	0.6543326359485	0.779794645791133
GO:0008307	structural constituent of muscle	1/465	42/18639	0.0238095238095238	0.954377880184332	0.6543326359485	0.779794645791133
GO:0016859	cis-trans isomerase activity	1/465	42/18639	0.0238095238095238	0.954377880184332	0.6543326359485	0.779794645791133
GO:0019894	kinesin binding	1/465	42/18639	0.0238095238095238	0.954377880184332	0.6543326359485	0.779794645791133
GO:0031492	nucleosomal DNA binding	1/465	42/18639	0.0238095238095238	0.954377880184332	0.6543326359485	0.779794645791133
GO:0015297	antiporter activity	3/465	135/18639	0.0222222222222222	0.890752688172043	0.658376619759954	0.783458481246013
GO:0008200	ion channel inhibitor activity	1/465	43/18639	0.0232558139534884	0.93218304576144	0.66297571409465	0.786614356811274
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/465	43/18639	0.0232558139534884	0.93218304576144	0.66297571409465	0.786614356811274
GO:0003779	actin binding	10/465	443/18639	0.0225733634311512	0.904827787082211	0.670530614271538	0.790807189418622
GO:0001223	transcription coactivator binding	1/465	44/18639	0.0227272727272727	0.91099706744868	0.671403133590563	0.790807189418622
GO:0003954	NADH dehydrogenase activity	1/465	44/18639	0.0227272727272727	0.91099706744868	0.671403133590563	0.790807189418622
GO:0016248	channel inhibitor activity	1/465	44/18639	0.0227272727272727	0.91099706744868	0.671403133590563	0.790807189418622
GO:0043014	alpha-tubulin binding	1/465	44/18639	0.0227272727272727	0.91099706744868	0.671403133590563	0.790807189418622
GO:0051020	GTPase binding	7/465	315/18639	0.0222222222222222	0.890752688172043	0.674011152113643	0.792723451103091
GO:0140101	catalytic activity, acting on a tRNA	3/465	139/18639	0.0215827338129496	0.865119517289394	0.677641623671736	0.794693449260126
GO:0051219	phosphoprotein binding	2/465	93/18639	0.021505376344086	0.862018730489074	0.678306394790638	0.794693449260126
GO:0046915	transition metal ion transmembrane transporter activity	1/465	45/18639	0.0222222222222222	0.890752688172043	0.679620264156865	0.794693449260126
GO:0141110	transporter inhibitor activity	1/465	45/18639	0.0222222222222222	0.890752688172043	0.679620264156865	0.794693449260126
GO:0000287	magnesium ion binding	5/465	230/18639	0.0217391304347826	0.871388499298738	0.683100679418371	0.796457935021708
GO:0005085	guanyl-nucleotide exchange factor activity	5/465	230/18639	0.0217391304347826	0.871388499298738	0.683100679418371	0.796457935021708
GO:0015276	ligand-gated monoatomic ion channel activity	4/465	186/18639	0.021505376344086	0.862018730489074	0.685461920179891	0.798059411390997
GO:0008234	cysteine-type peptidase activity	4/465	187/18639	0.0213903743315508	0.857409004657582	0.689491414273886	0.800454607780353
GO:0022834	ligand-gated channel activity	4/465	188/18639	0.0212765957446809	0.852848318462594	0.693484293413246	0.800454607780353
GO:0046943	carboxylic acid transmembrane transporter activity	4/465	188/18639	0.0212765957446809	0.852848318462594	0.693484293413246	0.800454607780353
GO:0140597	protein carrier chaperone	4/465	188/18639	0.0212765957446809	0.852848318462594	0.693484293413246	0.800454607780353
GO:0001784	phosphotyrosine residue binding	1/465	47/18639	0.0212765957446809	0.852848318462594	0.695444473591346	0.800454607780353
GO:0043495	protein-membrane adaptor activity	1/465	47/18639	0.0212765957446809	0.852848318462594	0.695444473591346	0.800454607780353
GO:0061733	protein-lysine-acetyltransferase activity	1/465	47/18639	0.0212765957446809	0.852848318462594	0.695444473591346	0.800454607780353
GO:0140938	histone H3 methyltransferase activity	1/465	47/18639	0.0212765957446809	0.852848318462594	0.695444473591346	0.800454607780353
GO:0005342	organic acid transmembrane transporter activity	4/465	189/18639	0.0211640211640212	0.848335893497184	0.697440541707066	0.801610181649089
GO:0008188	neuropeptide receptor activity	1/465	48/18639	0.0208333333333333	0.83508064516129	0.703061637951287	0.805778444630695
GO:0038187	pattern recognition receptor activity	1/465	48/18639	0.0208333333333333	0.83508064516129	0.703061637951287	0.805778444630695
GO:0005249	voltage-gated potassium channel activity	2/465	98/18639	0.0204081632653061	0.818038183015141	0.705867047236391	0.807847838763462
GO:0015293	symporter activity	3/465	146/18639	0.0205479452054795	0.82364118426867	0.709399487196628	0.81074227108186
GO:0031267	small GTPase binding	6/465	283/18639	0.0212014134275618	0.84983472016414	0.712153335768746	0.812739965114614
GO:0032813	tumor necrosis factor receptor superfamily binding	1/465	50/18639	0.02	0.801677419354839	0.717730366843532	0.817949416656662
GO:0015291	secondary active transmembrane transporter activity	6/465	287/18639	0.0209059233449477	0.837990333820389	0.72461703392805	0.820211984670244
GO:0003743	translation initiation factor activity	1/465	51/18639	0.0196078431372549	0.78595825426945	0.724791283483359	0.820211984670244
GO:0016597	amino acid binding	1/465	51/18639	0.0196078431372549	0.78595825426945	0.724791283483359	0.820211984670244
GO:0016830	carbon-carbon lyase activity	1/465	51/18639	0.0196078431372549	0.78595825426945	0.724791283483359	0.820211984670244
GO:0030544	Hsp70 protein binding	1/465	51/18639	0.0196078431372549	0.78595825426945	0.724791283483359	0.820211984670244
GO:0030159	signaling receptor complex adaptor activity	1/465	52/18639	0.0192307692307692	0.770843672456576	0.731675943112165	0.826844981866614
GO:0005544	calcium-dependent phospholipid binding	1/465	53/18639	0.0188679245283019	0.756299452221546	0.738388736271515	0.829788732833636
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/465	53/18639	0.0188679245283019	0.756299452221546	0.738388736271515	0.829788732833636
GO:0140296	general transcription initiation factor binding	1/465	53/18639	0.0188679245283019	0.756299452221546	0.738388736271515	0.829788732833636
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/465	53/18639	0.0188679245283019	0.756299452221546	0.738388736271515	0.829788732833636
GO:0015485	cholesterol binding	1/465	54/18639	0.0185185185185185	0.742293906810036	0.744933944365443	0.832385046540115
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	1/465	54/18639	0.0185185185185185	0.742293906810036	0.744933944365443	0.832385046540115
GO:0017069	snRNA binding	1/465	54/18639	0.0185185185185185	0.742293906810036	0.744933944365443	0.832385046540115
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	1/465	54/18639	0.0185185185185185	0.742293906810036	0.744933944365443	0.832385046540115
GO:0000149	SNARE binding	2/465	106/18639	0.0188679245283019	0.756299452221546	0.745849967444361	0.832385046540115
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/465	56/18639	0.0178571428571429	0.715783410138249	0.757538201461393	0.844263264525249
GO:0004601	peroxidase activity	1/465	57/18639	0.0175438596491228	0.703225806451613	0.763605291614783	0.849852721246205
GO:0099106	ion channel regulator activity	3/465	160/18639	0.01875	0.751572580645161	0.765616194977683	0.849977358413083
GO:0051015	actin filament binding	4/465	209/18639	0.0191387559808612	0.767155425219941	0.768930649980434	0.849977358413083
GO:0008408	3'-5' exonuclease activity	1/465	58/18639	0.0172413793103448	0.691101223581757	0.769520884091327	0.849977358413083
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	1/465	58/18639	0.0172413793103448	0.691101223581757	0.769520884091327	0.849977358413083
GO:0008094	ATP-dependent activity, acting on DNA	4/465	210/18639	0.019047619047619	0.763502304147466	0.772129898743503	0.849977358413083
GO:0001786	phosphatidylserine binding	1/465	59/18639	0.0169491525423729	0.67938764352105	0.775288753899062	0.849977358413083
GO:0015459	potassium channel regulator activity	1/465	59/18639	0.0169491525423729	0.67938764352105	0.775288753899062	0.849977358413083
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	1/465	59/18639	0.0169491525423729	0.67938764352105	0.775288753899062	0.849977358413083
GO:0031593	polyubiquitin modification-dependent protein binding	1/465	59/18639	0.0169491525423729	0.67938764352105	0.775288753899062	0.849977358413083
GO:0036002	pre-mRNA binding	1/465	59/18639	0.0169491525423729	0.67938764352105	0.775288753899062	0.849977358413083
GO:0070063	RNA polymerase binding	1/465	59/18639	0.0169491525423729	0.67938764352105	0.775288753899062	0.849977358413083
GO:0001098	basal transcription machinery binding	1/465	60/18639	0.0166666666666667	0.668064516129032	0.780912582178768	0.851521412146349
GO:0001099	basal RNA polymerase II transcription machinery binding	1/465	60/18639	0.0166666666666667	0.668064516129032	0.780912582178768	0.851521412146349
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/465	60/18639	0.0166666666666667	0.668064516129032	0.780912582178768	0.851521412146349
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/465	60/18639	0.0166666666666667	0.668064516129032	0.780912582178768	0.851521412146349
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	1/465	61/18639	0.0163934426229508	0.657112638815442	0.786395958533086	0.855912117981163
GO:0009055	electron transfer activity	2/465	116/18639	0.0172413793103448	0.691101223581757	0.789196490856498	0.855912117981163
GO:0015294	solute:monoatomic cation symporter activity	2/465	116/18639	0.0172413793103448	0.691101223581757	0.789196490856498	0.855912117981163
GO:0005216	monoatomic ion channel activity	9/465	448/18639	0.0200892857142857	0.80525633640553	0.789957945525204	0.855912117981163
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	3/465	167/18639	0.0179640718562874	0.72006953834267	0.790235693086569	0.855912117981163
GO:0016247	channel regulator activity	3/465	168/18639	0.0178571428571429	0.715783410138249	0.793571691057035	0.858374734101853
GO:0005507	copper ion binding	1/465	63/18639	0.0158730158730159	0.636251920122888	0.796955269757923	0.858586477285869
GO:0022824	transmitter-gated monoatomic ion channel activity	1/465	63/18639	0.0158730158730159	0.636251920122888	0.796955269757923	0.858586477285869
GO:0022835	transmitter-gated channel activity	1/465	63/18639	0.0158730158730159	0.636251920122888	0.796955269757923	0.858586477285869
GO:0141108	transporter regulator activity	3/465	170/18639	0.0176470588235294	0.707362428842505	0.800111278534769	0.860838765720497
GO:0008514	organic anion transmembrane transporter activity	5/465	269/18639	0.0185873605947955	0.745053363712675	0.804496882463894	0.864406224775035
GO:0019843	rRNA binding	1/465	65/18639	0.0153846153846154	0.616674937965261	0.806993658552194	0.865159014060439
GO:0004540	RNA nuclease activity	2/465	121/18639	0.0165289256198347	0.662543321780858	0.808328712490824	0.865159014060439
GO:0022836	gated channel activity	6/465	318/18639	0.0188679245283019	0.756299452221546	0.808409722296574	0.865159014060439
GO:0030145	manganese ion binding	1/465	68/18639	0.0147058823529412	0.589468690702087	0.821130266595307	0.874691662818994
GO:0032934	sterol binding	1/465	68/18639	0.0147058823529412	0.589468690702087	0.821130266595307	0.874691662818994
GO:0140223	general transcription initiation factor activity	1/465	68/18639	0.0147058823529412	0.589468690702087	0.821130266595307	0.874691662818994
GO:0043021	ribonucleoprotein complex binding	3/465	177/18639	0.0169491525423729	0.67938764352105	0.821647242672793	0.874691662818994
GO:0002039	p53 binding	1/465	69/18639	0.0144927536231884	0.580925666199158	0.825608992890778	0.87659929862779
GO:0098960	postsynaptic neurotransmitter receptor activity	1/465	69/18639	0.0144927536231884	0.580925666199158	0.825608992890778	0.87659929862779
GO:0008028	monocarboxylic acid transmembrane transporter activity	1/465	70/18639	0.0142857142857143	0.572626728110599	0.829975811324046	0.878925891939487
GO:0016782	transferase activity, transferring sulphur-containing groups	1/465	70/18639	0.0142857142857143	0.572626728110599	0.829975811324046	0.878925891939487
GO:0030246	carbohydrate binding	5/465	280/18639	0.0178571428571429	0.715783410138249	0.831173962688266	0.879042620225286
GO:0031490	chromatin DNA binding	2/465	128/18639	0.015625	0.626310483870968	0.832514565016214	0.879309501350459
GO:0035591	signaling adaptor activity	2/465	129/18639	0.0155038759689922	0.62145536384096	0.83573601262651	0.881559658227441
GO:0004521	RNA endonuclease activity	1/465	73/18639	0.0136986301369863	0.54909412284578	0.842432377177976	0.885156515942529
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/465	73/18639	0.0136986301369863	0.54909412284578	0.842432377177976	0.885156515942529
GO:0043539	protein serine/threonine kinase activator activity	1/465	73/18639	0.0136986301369863	0.54909412284578	0.842432377177976	0.885156515942529
GO:0015078	proton transmembrane transporter activity	3/465	185/18639	0.0162162162162162	0.650008718395815	0.843810318640496	0.885452905794183
GO:0048029	monosaccharide binding	1/465	74/18639	0.0135135135135135	0.541673931996513	0.846378781606083	0.88699618098277
GO:0019003	GDP binding	1/465	75/18639	0.0133333333333333	0.534451612903226	0.850226552495023	0.889874422818625
GO:0140098	catalytic activity, acting on RNA	7/465	387/18639	0.0180878552971576	0.725031257814454	0.852597129173778	0.891201138903509
GO:0000049	tRNA binding	1/465	80/18639	0.0125	0.501048387096774	0.868069892440796	0.906202161617782
GO:0030971	receptor tyrosine kinase binding	1/465	81/18639	0.0123456790123457	0.494862604540024	0.871375431533152	0.907386131740741
GO:0140104	molecular carrier activity	4/465	249/18639	0.0160642570281124	0.643917605907501	0.871672521738292	0.907386131740741
GO:0016758	hexosyltransferase activity	3/465	197/18639	0.0152284263959391	0.610414278696578	0.872573049953658	0.907386131740741
GO:0022843	voltage-gated monoatomic cation channel activity	2/465	143/18639	0.013986013986014	0.560613579968419	0.87530208313389	0.909054091480955
GO:0008135	translation factor activity, RNA binding	1/465	83/18639	0.0120481927710843	0.482938204430626	0.877740629632938	0.910416468220044
GO:0180051	translation factor activity	1/465	84/18639	0.0119047619047619	0.477188940092166	0.880804361429699	0.912422979532303
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	1/465	86/18639	0.0116279069767442	0.46609152288072	0.88670389505838	0.916595135482561
GO:0008168	methyltransferase activity	3/465	204/18639	0.0147058823529412	0.589468690702087	0.887100737558617	0.916595135482561
GO:0004197	cysteine-type endopeptidase activity	1/465	88/18639	0.0113636363636364	0.45549853372434	0.892312030800824	0.919627705213094
GO:0016651	oxidoreductase activity, acting on NAD(P)H	1/465	88/18639	0.0113636363636364	0.45549853372434	0.892312030800824	0.919627705213094
GO:0005506	iron ion binding	2/465	154/18639	0.012987012987013	0.520569752827817	0.900019422105035	0.925405781756369
GO:0072341	modified amino acid binding	1/465	91/18639	0.010989010989011	0.440482098546615	0.900209089678844	0.925405781756369
GO:0052689	carboxylic ester hydrolase activity	1/465	92/18639	0.0108695652173913	0.435694249649369	0.902710856624031	0.926798439837633
GO:0051213	dioxygenase activity	1/465	93/18639	0.010752688172043	0.431009365244537	0.905150035557003	0.928123386713272
GO:0016741	transferase activity, transferring one-carbon groups	3/465	215/18639	0.013953488372093	0.559309827456864	0.906956560343685	0.928797085877943
GO:0030594	neurotransmitter receptor activity	1/465	97/18639	0.0103092783505155	0.413235783172597	0.914311543196964	0.935143958105249
GO:0004497	monooxygenase activity	1/465	106/18639	0.00943396226415094	0.378149726110773	0.931824449023177	0.95049534463891
GO:0005244	voltage-gated monoatomic ion channel activity	2/465	173/18639	0.0115606936416185	0.46339735222823	0.932269297850184	0.95049534463891
GO:0003735	structural constituent of ribosome	2/465	175/18639	0.0114285714285714	0.458101382488479	0.935023624899778	0.95049534463891
GO:0022832	voltage-gated channel activity	2/465	175/18639	0.0114285714285714	0.458101382488479	0.935023624899778	0.95049534463891
GO:0005496	steroid binding	1/465	108/18639	0.00925925925925926	0.371146953405018	0.935202721519719	0.95049534463891
GO:0016853	isomerase activity	2/465	180/18639	0.0111111111111111	0.445376344086022	0.941452892714036	0.954460220426903
GO:0043022	ribosome binding	1/465	112/18639	0.00892857142857143	0.357891705069124	0.941466331287428	0.954460220426903
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	2/465	181/18639	0.0110497237569061	0.442915701301016	0.942664163130311	0.954476997254751
GO:0015108	chloride transmembrane transporter activity	1/465	121/18639	0.00826446280991736	0.331271660890429	0.953438105670277	0.964177708863059
GO:0004519	endonuclease activity	1/465	127/18639	0.0078740157480315	0.315621031242062	0.960028228854799	0.969628511143347
GO:0016829	lyase activity	2/465	200/18639	0.01	0.400838709677419	0.961612549275233	0.970016154574767
GO:0140097	catalytic activity, acting on DNA	4/465	336/18639	0.0119047619047619	0.477188940092166	0.969904628679888	0.977160773034102
GO:0020037	heme binding	1/465	142/18639	0.00704225352112676	0.282280781462971	0.972712418892514	0.978769158736179
GO:0008509	monoatomic anion transmembrane transporter activity	1/465	149/18639	0.00671140939597315	0.269019268239879	0.977167654020385	0.982029184637402
GO:0046906	tetrapyrrole binding	1/465	152/18639	0.00657894736842105	0.263709677419355	0.978847397634932	0.982495276135435
GO:0015103	inorganic anion transmembrane transporter activity	1/465	165/18639	0.00606060606060606	0.242932551319648	0.984812315065934	0.987256018080986
GO:0045182	translation regulator activity	2/465	356/18639	0.00561797752808989	0.225190286335629	0.998829980641571	0.999772160153199
GO:0030371	translation repressor activity	1/465	329/18639	0.00303951367781155	0.121835474066085	0.999772160153199	0.999772160153199